[ { "cls_id": "homologset.agr.SGD:S000000852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2L5-1", "uniprot_id": "RT18C_MOUSE", "id": "Q8R2L5-1", "name": "Small ribosomal subunit protein bS18m", "aln": "-MAALVALCSGIGRKNLT---TAAGCFTDRGTQAVSVIWRRCFSQFEQVTSNEDL------------------PVPM------ENPYKEPL-----------------KK------------------------------------------------------------------------------------------------CVLCEK----RVDYKNVQLLSQ---------------FISPFTGC--IYGRHITGLCGKKQREITKA-----IKRAQKMGFMPVTYKDPAYLKDPR--------------------------------------------------------------------VCNIRYRE---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3D5-1", "uniprot_id": "RT18C_HUMAN", "id": "Q9Y3D5-1", "name": "Small ribosomal subunit protein bS18m", "aln": "-MAAVVAVCGGLGRKKLTHLVTAAVSLTHPGTH--TVLWRRGCSQ--QVSSNEDL------------------PISM------ENPYKEPL-----------------KK------------------------------------------------------------------------------------------------CILCGK----HVDYKNVQLLSQ---------------FVSPFTGC--IYGRHITGLCGKKQKEITKA-----IKRAQIMGFMPVTYKDPAYLKDPK--------------------------------------------------------------------VCNIRYRE---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LDD4-1", "uniprot_id": "A0ABK0LDD4_RAT", "id": "A0ABK0LDD4-1", "name": "", "aln": "-MAGLLALRSCIGRKNLT---TATGCFTDRATHAVSVPWRRCFSQYEQVTSNEDLWATLRIEKGAPKESVLKSPASMGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFHYISPKLTIVWVLGVLVRYCFLLPLRVTLAFIGISLLIIGTTLVGQLPDSSLKNWLSELVHLTCCRICVRSLSGTIHYHNKQYRPQKGGICVANHTSPIDVLILATDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEIKDRHLVTKRLKEHIADKKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIYPVAIKYNPQFGDAFWNSSKYNLVSYLLRIMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKTYSKMIVGNGSPSLALDSSTVDNHGSPEPAFRSESL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VA81-1", "uniprot_id": "Q9VA81_DROME", "id": "Q9VA81-1", "name": "", "aln": "--------------------MLKLGKFLAQNATLVNLVGRQQLGTVSRLYSAAPE------------------SSDLDLPIDIKNPYEKDP-----------QQ------------------------------------------------------------------------------------------------------CILCKHS--IEPHYKNVKLLSQ---------------FQSPYTGR--IYGRHITGLCKRRQEQVEQA-----ILRAQQCLLMPGYHKDLDFLQDPK--------------------------------------------------------------------LFDPERPVRPHKY----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6PDU2-1", "uniprot_id": "Q6PDU2_RAT", "id": "Q6PDU2-1", "name": "Large ribosomal subunit protein mL66", "aln": "-MAALRALVSGCGR-------QLQTLLAGPAATGWLWLPARGLREVVKIQEGKTTVIEG--------------RVTESPKATPDPPNPSGQ-------------------------------------------------------------------------------------------------------------------CPICRWNLKHKYNYEDVLLLSQ---------------FIRPHGGM---LPRRITGLCREEHRKMEEC-----VKMAHRAGLFPNHRPRLPEGCSPKDKPKLN--------------------------------------------------------------RYLTRWAPKSVKPIYKKGHPWN---KNAGIKCTPAWEDPHEDGARAVTRPVGYNP----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N85-1", "uniprot_id": "RT18A_MOUSE", "id": "Q99N85-1", "name": "Large ribosomal subunit protein mL66", "aln": "-MAALRRLVSGCGR-------QLQAFLAGPAATGWLWLPARGLREVVKIQEGKTTVIEG--------------RITETPKATPDPPNPSGQ-------------------------------------------------------------------------------------------------------------------CPICRWNLKHKYTYEDVLLLSQ---------------FIRPYGGM---LPRRVTGLCREEHRKIEEC-----VKMAHRAGLLPNHRPQLPEGCLPKDKPKLN--------------------------------------------------------------RYLTRWAPKSVKPIYKKGHRWN---KVGMAVGSPLLKD----NVCYSRRPLKMMH----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVS2-1", "uniprot_id": "RT18A_HUMAN", "id": "Q9NVS2-1", "name": "Large ribosomal subunit protein mL66", "aln": "-MAALKALVSGCGR-------LLRGLLAGPAATSWSRLPARGFREVVETQEGKTTIIEG--------------RITATPKESPNPPNPSGQ-------------------------------------------------------------------------------------------------------------------CPICRWNLKHKYNYDDVLLLSQ---------------FIRPHGGM---LPRKITGLCQEEHRKIEEC-----VKMAHRAGLLPNHRPRLPEGVVPKSKPQLN--------------------------------------------------------------RYLTRWAPGSVKPIYKKGPRWN---RVRMPVGSPLLRD----NVCYSRTPWKLYH----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHQ0-1", "uniprot_id": "Q9VHQ0_DROME", "id": "Q9VHQ0-1", "name": "Large ribosomal subunit protein mL66", "aln": "-MSFVLQLAT------------RTVRSTIAQVRGVATTMPRQIKEIHEKQENSVKIFEG------------VNVESPRAHLMLKSACQTKF-------------------------------------------------------------------------------------------------------------------CPECTLG--LDIKHTDVLILSQ---------------YVRSDGCM---LPRRITGLCHRQQKKMGTL-----VTMAQKAGLMPNLAPEWSKRDPKKRFGWR---------------------------------------------------------------KFNKYFLESTIKY----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40033-1", "uniprot_id": "RSM18_YEAST", "id": "P40033-1", "name": "Small ribosomal subunit protein bS18m", "aln": "MQPIIKGAVSSTFKRALYNFGIKEKKSVNIEMGRTQQTKKIDQSLSKKLPKGTIYDPFDFSMG----------RIHLDRKYQANKNSNRND---------------------------------------------------------------------------------------------------------------------IMKSGANPLEFYARPRILSR---------------YVTSTGRI---QHRDITGLSAKNQRRLSKA-----IRRCQAIGLM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .: . : ** :. : . .. ", "identical_positions": 2, "similar_positions": 14, "identity": "0.43%" }, { "cls_id": "homologset.agr.SGD:S000000853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PZC6-1", "uniprot_id": "A0A8M1PZC6_DANRE", "id": "A0A8M1PZC6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEAKSR------------YSKR--------------LRSGTRRRYQD-DGISD-DEIEGKRSFDLEEKLQSDRYNSN-LVKIMDGKDFTLEYIQR----------------EGLRDPIIFKKADGLGIKMPDP-----DFSVSDVKLFVGSRRMIDVMDAATQKGIEMSMGQWRRYYETPA-SQREKLYNVISLEFSHTKLEHLVKRPTSVDMIDWVDNMWPRHLKERQRDSTNAITDMQYPKVQKYCLMSVEGCFTDFHIDFGGTSVWYHIHKGGKVFWLIPPTPQNLELYENWVLSAKQGDIFLGDKASMCQRIELKQGYTFMIPSGWIHAVYTPMDTLVFGGNFLHSFNIPMQLNIFNIEDRTRVPSKFRYPFYFEMCWYVLERYLYCLTNTSHLTPEFQKHSLGIGLKKEDVIKPAKPDGDSESEDEEVV-------------------------------------KEEPEEEAVTPPARPGV--------------------------------------------------------------KVHLAPFELEGLWALLHKLEDLPAHKKCVPAGIRNAP-------ALLSDIRKLLEEHANDNPKLSYTGKPIVKWPKRPS-------------WYQPPPP---PPPSHLYRPRAPGSGPMLAPVPRPVKPSSS--------------ISALRRRRVRCKR--------------------CEACLRTECGNCNYCRDMRKFGGPGRLKKSCVLRQCLAPALPLTAVCVICKEGNQ----------ESDDTESVQMLMECSECAQITHPECIKVP---------GEGVINKDLPSCWECPKCVQGKKTESSSSSEEE-----------------------TDSSVSN-SSRLSGPPAKRAYREGIGVEGLRIARRGRSSISPSSLPITRSRRQPPPSQRLLLQHQQNRKRAGALELQLRKR--IKLERNKILQSTRSPVSLSPKLLRQRSLE-RRGLIRAGPGQSLSRGRGSSSFRGRGLRVRGGGRGGGLRERMEMAVEREDSAEEEQQERKENGQYNGKENRPQRLSGKAGEDENGDAHRNGESEESSE----------------GGEP------TLSDTS--------AALTDDVRGQESCVTVKLQ-PSRAKRDPSTIVPKLEANLSSRSLPPSHKALLRPPLRNGARCSDAPHSPADRLHVNKSHALSSSSHTLTRRASKNSNLRSNFEDSTHRLTRERIQKNARSERAKSSD-SCPSSTFHSGGGNEPGWEKEVWVSVFRYLTRAELCVCMAVCKSWYKWGCDKRLWTRISLSRSRSMSPQVLTGIIKRQPVTLDLSWANITKKQLSWLINRLPGLKDLVLSGCNWSSVSALSSPSCPLLRSLDLSWADGIKDAQIRELLNP-----PGSDN-------------------------RSQMKNMQCLWLCGLEVTEATLRLIIRHMPLLTRLELSRCP-ITDGALNLLSAVGSSTRNTLTHLNLAGCTQLTDRCLVYLRRLSCLSILDLRDCKGVSVQACQSFISELSVNTLYYLS-----------------DDKLIERIS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B724-1", "uniprot_id": "A0A8M2B724_DANRE", "id": "A0A8M2B724-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENGQEVLTLVDGGMLLMRRR------------GRKRKSQ---QGDEDVTLKRSGTRRRYQD-DGISD-DEIDGRRTFDLEEKLHSSFFSSD-RVKRMEGKDFSYEYVQR----------------HGLRDPIIFEKPEGLGIKMPDP-----DFTVNDVKLFVGSRRIVDVMDVATQKGTEMSMAQWRRYYETPP-SQREKLYNVISLEFSHTKLETLVKRPSTVDMIDWVDNMWPRHLKERQRDSTNSIMEMQYPKVQKYCLMSVQGCYTDFHIDFGGTSVWYHIHKGCKVFWLIPPTPQNLELYENWVLSGKQGDIFLGDRATDCQRIELKQGYTFIIPSGWIHAVYTPVDTLVFGGNFLHSFNVPMQLDISGIEDRTRVPVKFRYPFFFEMCWYVLERYLYSLTNKSHLIPEFQKHSLGIGLKRE----------NSEVLNGHAK-------------------------------------EERDEMDAPSPPSAPGL--------------------------------------------------------------KTHLTAFELEGLWRLVGKLESLPSNKKCVPSGIHNAA-------ALLLDIRALLKEHANDIPKLSYTGRPIVRWPKRPP-------------WYQPPPP---PPP--VMRPKLATT----PIVPRPVKPASN--------------MSVLRRRRVRCKR--------------------CEACLRTECGDCNFCRDMKKFGGPGKLKQTCVLRQCLAPGLPLSAVCELCGEGNQ----------ETS-----EELMECSNCAQIAHPSCLKTS---------GEGVVNKDLPSCWECPKCVLGKDTDSESSGSGDDITAQDGSGGRGGEGGAWHGVGRPPSSLSHGSLQKRAAAPEQRLRKRIKLDGGKSHKRKSSSLDPRVAKIYRRHGMEHDDDSGSDDDGDGGRMSSVRSSVSSSRRGYGASRRGVWRGSSQRGPRGGGSLSSSSLKMRRGLGARGERGGRVRLRGGSQMRRRRYETDDDDDDDDDDDDDDDDDDDEDEDDEDDSEEDRHVSRSEKEHRSRRRR-RRGDDYDDDEDEDDDDEEDSEEQDYEGEDDEMEDLDDGGDEDDEDGENQSDSDPDPPVLLVSDLNDDLLN-DSYLTVTLHRPPKAKRDPGSIVPKLEAAMSPRTGG-SSGFMQRKTLPK-ARPKTSSSTPAG------NGLSQAKSGRPTRRSSNQDGRERDTASPSSMSSRSSVSPPPPPPAVTSSSPSLLSHPSFRDAGNELGCEKDIWVSVFRYLDRTDLAVCMRVCKAWFKWCCDKRLWTRIDLSRCRALSPQAVTAIIKLQPVTLDLSWTPVSKKQLAWLIHHLPSLKDLIMSGCSSLCVSALSSPSCPSLRTLDLCWAVGVKDSQIKDLIVQ-----PGSES-------------------------RSRLRSLVSLRLSGLELSDAVIKTMVRHMPSLRQLDLSYCQGLTDQSINLLTATGCNTRNTLRQLNLSGCNKLSDGCLSYMKRLSALALLDLRGCKNVTRHGCENFISDLSYCTVFCLT-----------------EDKLIQRVS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P59997-1", "uniprot_id": "KDM2A_MOUSE", "id": "P59997-1", "name": "Lysine-specific demethylase 2A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPEEERIR------------YSQR--------------LRGTMRRRYED-DGISD-DEIEGKRTFDLEEKLQTNKYNAN-FVTFMEGKDFNVEYIQR----------------GGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQWPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLISVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMELN---ELESGNGDEEGVDREAR-------------------------------------RMNNKRSVLTSPVANGVNLDYDGLGKACRSL-------------PSLKKTLSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDED-------ALIADVKILLEELASSDPKLALTGVPIVQWPKRDK-------------LKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI--------------VSGARRRRVRCRK--------------------CKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQ----------NEETQDFEKKLMECCICNEIVHPGCLQMD---------GEGLLNEELPNCWECPKCYQEDSSDKAQKRKIE-----------------------------------------ESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRPNPRVLMQHCPARNPQHGDEEGLGGEEEEEEEEEE-DDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTD-KPGQDN-------------------------RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLS-----------------DEKLIQKIS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARD6-1", "uniprot_id": "A0A8I6ARD6_RAT", "id": "A0A8I6ARD6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VG------------REEG--------------KRGTMRRRYED-DGISD-DEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQR----------------GGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDMELN---ELESGNGDEEGADKEAR-------------------------------------RMNSKRSVLTSPVANGVNLDYDGLGKACRSL-------------PNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDED-------ALIADVKILLEELASSDPKLALTGVPIVQWPKRDK-------------LKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI--------------VSGARRRRVRCRK--------------------CKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQ----------NEETQDFEKKLMECCICNEIVHPGCLQMD---------GEGLLNEELPNCWECPKCYQEDSSEKAQKRKIE-----------------------------------------ESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEE-DDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTD-KPGQDN-------------------------RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLS-----------------DEKLIQKIS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K7-1", "uniprot_id": "KDM2A_HUMAN", "id": "Q9Y2K7-1", "name": "Lysine-specific demethylase 2A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPEEERIR------------YSQR--------------LRGTMRRRYED-DGISD-DEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQR----------------GGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDLELN---GLESGNGDEEAVDREPR-------------------------------------RLSSRRSVLTSPVANGVNLDYDGLGKTCRSL-------------PSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDED-------ALIADVKILLEELANSDPKLALTGVPIVQWPKRDK-------------LKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI--------------VSGARRRRVRCRK--------------------CKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQ----------NEETQDFEKKLMECCICNEIVHPGCLQMD---------GEGLLNEELPNCWECPKCYQEDSSEKAQKRKME-----------------------------------------ESDEEAVQAKVLRPLRSCDEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRHSPRVLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPAD-KPGQDN-------------------------RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLS-----------------DEKLIQKIS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P1G2-1", "uniprot_id": "KDM2B_MOUSE", "id": "Q6P1G2-1", "name": "Lysine-specific demethylase 2B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEKD-------------SGRR--------------LRAIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGD-FVHAMEGKDFNYEYVQR----------------EALRVPLVFRDKDGLGIKMPDP-----DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPE-AQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNALAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSYLTQEYQRELMLIDAPRKTSVDGFSSDSWLDMEEESCEQQPQEEEE-----------------------EEEDKEEEGDGADKTPKPPTDDPTSPTSTPPEDQDSTGKKPKAPAIRFLKRTLSNESEESVKSTSMPTDDPKTPTGSPATEVSTKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQ-------ALLEGVKNVLKEHVDDDPTLAITGVPVVSWPKKTA-------------KNRVVGR----PKGKLG---------PASAVK--LAANRT--------------TAGARRRRTRCRK--------------------CEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDT------VEEEEGKFNLMLMECSICNEIIHPGCLKIKE--------SEGVVNDELPNCWECPKCNHAGKTG---KQKRG------------------------------------PGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPADGILRR--KSDDVHLR----RKRK-YEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRLSLANKPLRRFKQEPEDDLPEAPPKTRESDQSRSSSPTAGPSTEGAEGP---------------------------------------EEKKKVKMRRKRRLVNKELSKELSKELNHEIQKTESTLAHESQQPIKSEPESENDEPKRPLSHCERPHRFSKG------LNGTPRELRHSLGPGLRSPPRVMSRPPPSASPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHRDLCVCMRVCRTWNRWCCDKRLWTRIDLNRCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDN------------------------RSKLRNIVELRLAGLDITDVSLRLIIRHMPLLSKLQLSYCNHINDQSINLLTAVGTTTRDSLTEVNLSDCNKVTDLCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQV-----------------EEKLLQKLS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIT9-1", "uniprot_id": "A0ABK0LIT9_RAT", "id": "A0ABK0LIT9-1", "name": "Lysine-specific demethylase 2B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEKD-------------SGRR--------------LRAIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGD-FVHAMEGKDFNYEYVQR----------------EALRVPLVFRDKDGLGIKMPDP-----DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPE-AQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNALAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSYLTQEYQRELMLIDAPRKNSVDGFSSDSWLEMEEESREQQLQEEE---------------------------DKEEEGDGADKTPKPPTEGPTSPTSTQSEDQDSTGKKPKAPAMRFLKRTLSNESEESVKSTAMPVDYPKTPTGSPATEVSTKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQ-------ALLEGVKNVLKEHVDDDPNLAITGVPVVSWPKKTP-------------KNRVVGR----PKGKLG---------PASAVK--LAANRT--------------TAGARRRRTRCRK--------------------CEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDT------VEEEEGKFNLMLMECSICNEIIHPGCLKIKE--------SEGVVNDELPNCWECPKCNHAGKTGKAYKQKRG------------------------------------PGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPTDGILRR--KSDDVHLR----RKRK-YEKPQELSARKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLLRKKRRSWKNAEDRLSLANKPLRRFKQEPEDDLPEAPPKTRESDQSRSSSPTAGPSTEGAEGP---------------------------------------EEKRKVKMRRKRRLPNKELSKELSKELNHEIQKTESTLAHENHQPIKSEPESENEEPKRPLSHCERPHRFSKG------LNGTPRELRHSLGPGLRSPPRVISRPPPSTSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDN------------------------RSKLRNIVELRLAGLDITDVSLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQV-----------------EEKLLQKLS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NHM5-1", "uniprot_id": "KDM2B_HUMAN", "id": "Q8NHM5-1", "name": "Lysine-specific demethylase 2B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESAT--------------QRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGD-FVHAMEGKDFNYEYVQR----------------EALRVPLIFREKDGLGIKMPDP-----DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPE-AQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEE---------------------------EKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQ-------ALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTP-------------KNRAVGR----PKGKLG---------PASAVK--LAANRT--------------TAGARRRRTRCRK--------------------CEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDT------VEEEEGKFNLMLMECSICNEIIHPGCLKIKE--------SEGVVNDELPNCWECPKCNHAGKTG---KQKRG------------------------------------PGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRR--KSDDVHLR----KKRK-YEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGP---------------------------------------EEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKG------LNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDN------------------------RSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQV-----------------EEKLLQKLS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVL5-1", "uniprot_id": "A0AB32TVL5_DANRE", "id": "A0AB32TVL5-1", "name": "Lysine-specific demethylase 2B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEACAE-------------SGRK--------------LRSICRRMYDENEDLSDVEEITNVRGFSLEDKLDSASYNSQ-LVQFMEGKDFTYEYVQR----------------EALRTPLVFKAKDGLGIRMPDP-----EFTVSEIKGLVGSRRPVDVMDVSTQKGSEMSMAQFVRYYETPE-DERDKLFNVISLEFSHTKLENLIKRPTVVDLVDWVDNMWPRHLKQKQTEATNVMSEMKYPKVQRYCLMSVKGCFTDFHIDFGGTSVWYHVFKGQKVFWLIPPNAHNLSLYEDWVLSGKQSDIFLGDRADGCQRVELKQGYTFFIPSGWIHAVYTPEDTLVFGGNILHSFNIPMQLTVYEIENRTKVHSKFRYPFFYEMCWYVLERYVSCLTKRSHLSLEFRN----HTAEPKPVTESLMSATRLDMEEDSCG-------------------------------------TEGTILSSFSIPP-----CQTFKPS----------------------ANDSEDSSKS--LPSECPKTPSGSPGMDHSGKWSHLTEFELNGLKALVEKLESLPENKKCVPEGIEDPQ-------ALLDDVKVVLKEHADDNPKLAISGSPIVCWPKKTF-------------KPRPLNR----PKPKMGSSPCAAPGSTAGGMK--LSSGRG--------------SSSARRRRTRCRK--------------------CEACTRKECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCVVCGEAGKEDT------VEGEDDKFSMMLMECSICSEIIHPACLKDKD--------AGGVVNDELPNCWECPKCNHAGKTGKATKQKRG------------------------------------PGFKYASNLPGSLLKEQRTIIKEEPDMSTETAAVSPITKRKTEDDDNPTCKSEDAIKKRSPKLEDNPLR----KKRKLFEKDSDSNSIIRKKKKRTNP---DDLSTSLILGHIKK--EREDDEEYEEQNQP---ERSFVPSEEEDGDDERDEEEEEKALSSRKENGK-----VSHKTLESDQSQGGLTQAGPSSTDAQS------------------------------------------KSQRKAKRKPRLPNKELSKELSKQLNQEIQKTEDRLAHQNGRTVKTEPSSDGED-RKPLNNGSSHLRDWLGP--KWELNGSLREQTP-VSLIRTTTPAPVFRPTPCRSPPKCVQMERHVIRPPPISPPPDRLPLDDGKNHVLRREVWMGVFSHLIHKDLCVCMSVCKTWNRWCCDKRLWTKIDLNRCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRVLLLAGCSWAAVSALCTSSCPLLRNLDVQWVEGLKDNQIRDLLSPPTDNRPGQLDC------------------------RSKLRNVEDLCLAGLDITDTSLKLIIKHMPLLSQLDLSYCNHITDHSVNILTAAGTTTRDSLTHINLSVCNRVTDLSLTYFKRCGNICQIDLRYCKQVTKEGCEQFIAEMSVSVQFRLM-----------------EEKLLSKLS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH9-1", "uniprot_id": "JHD1_DROME", "id": "Q9VHH9-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAVETGSSPAKSNSNNSSSGGNNNNGNGNLSPNAKGVQRRQ------------LRERKQRKLYLEEWSLGDEDGEGTRGFSVAEKLESSKFAQAGMVREMRGCDLTVAFLQQ----------------HGFNIPLLFRDKAGLGLRMPDPQ----EFTVNDVRLCVGSRRLLDVMDVNTQKNLQMTMKEWQQYYDSP---QKDRLLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLGGMMYPKVQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGKQADIFFGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDSTKVPQKFRYPFFTEMLWYVLARYVHTLLGHSHLEGEASLSEDEMAARPHTHLTHHELFGLKEIVMYLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSPPGSQPPFLLYDRTRVKQEIKQEIARKNAEVIREQQQLEAGRAREAESDTSQSTGVGSVIGMGAGVEYSNGVMKKEQLENGSGVTVGGHGSQPEATFALPTDTLKYRPPKKMHLATALVAAAASSSSGGGGPVAGVGGSAVVGSSHSPTGGGVGPVTGAGGAISVIATSSSYIEGGQVGGILNMDNCHSPEGGGAKLSPNLTG-------------TGQPRRRRTRCKN--------------------CAACQRSDCGTCPFCMDMVKFGGPGRAKQTCMMRQCLSPMLPVTAQCVYCHLDGWRQTPVSPQTKQLASADGPSALMECSVCYEIAHPDCALSQLDGTEDAADAKGIVNEDLPNSWECPSCCRSGKNYDYKPRHFR------------------------------------ARQKSSEVRRVSVSHGQGGAEGHADGNTLLPPPVGQYNDFVFTSESEMESG----------------------TVSGHMTHWKHGMKRHHQLEVKTERNNSCDTPSPGISPNAIGGDSKVGKRRKSDDGTSVSSSMHESNDAPCGSSAEGAGGAGNANVSTNQWSGS---------------------------------------------------------------------------GGGGGSRKKNSIRSQLAQQMLNSSTRVLKKPQYVVRPASG-------------------------------------TGSSSSSGNGGSASATNGISNGSNQSGANSCGAGNGERGTNNGGLSGSNGLGNQHYSSSQNLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHK-MSASLLTAIVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDS------------------------KTRLRDLKVMKLAGTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTS-TTATARLTELNLSACRLVSENALEHLAKCEGLIWLDLRHVPQVSTQSVIRFASNS--KHDLCVR-----------------DIKLVERRRRNSTTANRSWHHD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4AD31-1", "uniprot_id": "D4AD31_RAT", "id": "D4AD31-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVP-----VYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEV---LHGPSIMKKRRGSSKGHDN----HKGKPLKTGSSMFIRELRGRTFDSSDEVILKPTGSQLTVEFLEE----------------NSFSVPILVLKKDGLGMTLPSP-----SFTVRDVEHYVGSDKEIDVIDVARQADCKMKLGDFVKYYYSG---KREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEEC------------VFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVEKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFKFPNFETICWYVGKHILDIFRGLRENRRHPAS--------------------------------------------------------------------------------------------------------------------------------------------------YLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQ--------LIKDLAREIRLVEDIFQQNVGKTSNIFGL------------------QRIFPAGSIPLTRPAHSTSVSMSK----------------------------LSLPSKNGSKKKGLK--------------------PKDIFKKA---ERKGKQSSALGPAGQLSYN------LMDPYSHQALKTGPSQKAKLNI--------------GGACLNDSDDDS-ADMDVDGSEN------PLALLMANGSTKRMKSVSKSRRAKIAKKVDSARLV---------------------------------------AEQVMGDEFDLDSDD-ELQIDERLG-KEKANL-----------------------------------------------------LMR------SKFPRKLPRAKPCSDPNRIREPG---EVEFDIEEDYTTDEDMVEGVESKLGNGSGAGGILDLLKASRQVG-------------------------------------------------------------------------------------GPDYAALTEAPASPS-TQEAIQGMLCMAN-------------------------------------LQSSSSSPATSSLQAWWTGGQDRSSGSSSSG----LGTVSNSP--ISQRTPGKRPIKRPAYWKNESEEEE--NASMDEQDSLGACFKDAEYIYPSLESDDDD-------------PALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQK-AQKKKYIKKKPLLKEVEQPRPQDSNTTM------------------TMPAPTLATTPQPVTSSSPQPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSSQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNG----------------------KLLL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TJ7-1", "uniprot_id": "PHF8_MOUSE", "id": "Q80TJ7-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVP-----VYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEV---LHGPSIMKKRRGSSKGHDN----HKGKPLKTGSSMFIRELRGRTFDSSDEVILKPTGSQLTVEFLEE----------------NSFSVPILVLKKDGLGMTLPSP-----SFTVRDVEHYVGSDKEIDVIDVARQADCKMKLGDFVKYYYSG---KREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEEC------------VFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVEKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFKFPNFETICWYVGKHILDIFRGLRENRRHPAS--------------------------------------------------------------------------------------------------------------------------------------------------YLVHGGKALNLAFRAWTKKEALPDHEDEIPETVRTVQ--------LIKDLAREIRLVEDIFQQNVGKTSNIFGL------------------QRIFPAGSIPLTKPAHSTSVSMSK----------------------------LSLPSKNGSKKKGLK--------------------PKDIFKKA---ERKGKQSSALGPAGQLSYN------LMDPYSHQALKTGPSQKAKFNM--------------SGTSLNDSDDDS-ADMDLDGSEN------PLALLMANGSTKRMKSVSKSRRAKIAKKVDSARLV---------------------------------------AEQVMGDEFDLDSDD-ELQIDERLG-KEKANL-----------------------------------------------------LIR------SKFPRKLPRAKPCSDPNRIREPG---EVEFDIEEDYTTDEDMVEGVESKLGNGSGAGGILDLLKASRQVG-------------------------------------------------------------------------------------GPDYAALTEAPASPS-TQEAIQGMLCMAN-------------------------------------LQSSSSSPATSSLQAWWTGGQERSSGSSSSG----LGTVSSSP--ASQRTPGKRPIKRPAYWKNESEEEE--NASLDEQDSLGACFKDAEYIYPSLESDDDD-------------PALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQK-AQKKKYIKKKPLLKEVEQPRPQDSNPIM------------------TMPAPTVATTPQPDTSSSPQPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSSQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNG----------------------KLLL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPP1-1", "uniprot_id": "PHF8_HUMAN", "id": "Q9UPP1-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRSRAIVQRGRVLPPPAPLDTTNLAGRRTLQGRAKMASVP-----VYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEV---LHGPSIMKKRRGSSKGHDT----HKGKPVKTGSPTFVRELRSRTFDSSDEVILKPTGNQLTVEFLEE----------------NSFSVPILVLKKDGLGMTLPSP-----SFTVRDVEHYVGSDKEIDVIDVTRQADCKMKLGDFVKYYYSG---KREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEEC------------VFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYVGKHILDIFRGLRENRRHPAS--------------------------------------------------------------------------------------------------------------------------------------------------YLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQ--------LIKDLAREIRLVEDIFQQNVGKTSNIFGL------------------QRIFPAGSIPLTRPAHSTSVSMSR----------------------------LSLPSKNGSKKKGLK--------------------PKELFKKA---ERKGKESSALGPAGQLSYN------LMDTYSHQALKTGSFQKAKFNI--------------TGACLNDSDDDS-PDLDLDGNES------PLALLMSNGSTKRVKSLSKSRRTKIAKKVDKARLM---------------------------------------AEQVMEDEFDLDSDD-ELQIDERLG-KEKATL-----------------------------------------------------IIR------PKFPRKLPRAKPCSDPNRVREPG---EVEFDIEEDYTTDEDMVEGVEGKLGNGSGAGGILDLLKASRQVG-------------------------------------------------------------------------------------GPDYAALTEAPASPS-TQEAIQGMLCMAN-------------------------------------LQSSSSSPATSSLQAWWTGGQDRSSGSSSSG----LGTVSNSP--ASQRTPGKRPIKRPAYWRTESEEEE-ENASLDEQDSLGACFKDAEYIYPSLESDDDD-------------PALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQK-AQKKKYIKKKPLLKEVEQPRPQDSNLSL------------------TVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSNQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNG----------------------KLLL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZJ51-1", "uniprot_id": "D3ZJ51_RAT", "id": "D3ZJ51-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVP-----VYCLCRQPYNVNHFMIECDLCQDWFHGSCVGIEEEKAVDIDIYHCPDCEV---IYGPSIMKKWPASSKEHEA----LKREPVKTGSPIFIHQLQGKTFDSSDEVILKPTGSQLTVEFLEE----------------SSFSIPILVLKKNGLGMTLPPT-----SFTVRDVEQYVGSDREIDVIDVACQASSKMMLGDFVKYYYSR---RREKVFNVINLEFSNTRLSNTVEMPKIVRKLSWVENLWPEEC------------GFERPTVQKYCLMSVQNSYTDFHIEFGGTSIWYHVLKGEKIFYLIHPTDANLTLFKCWSNSSNQKEMFFGDQVDKCYKCSVKQGQTLFIPTGWIYAVLTPVDCLAFGGNFLHSLNIEMQLKAYETEKHLSTAHLFKFPSFETICWHVGKHMLDIFEGLRENGRYPAP--------------------------------------------------------------------------------------------------------------------------------------------------YLVRGGKALNLAFQAWTRKEVLPDHEDEIPKTVQTVQ--------LIEDLAREICLVEDTSQQSIPKTSTIFGL------------------QQHHTNPSS-LNRQTHSTSVSTST----------------------------LSLPSKSGSEKKSPK--------------------YKDIFKKE---EQTSKERPTLGPNDQHSCN------FMDLNNHQELKVGFSQNVECNI--------------TSTCLNDSDDDSKFDKVCDGNES------LVPLLMANGSTKRVKSLSNSWRAKITKKEDKSKLV---------------------------------------EEKKMGDKFDLDTND-ELQTEKRLG-KVKDSL-----------------------------------------------------VVR------SKIPPNLPHVKFCSHQNQSCEPG---ETEIDIVENYKIDEGMMEGVEGKLKNGGESDGILDLLKARKQVG-------------------------------------------------------------------------------------GPGYVVLTDAPDYSS-SKENTQDTVFMAE-------------------------------------LQSSSPSPAPSTLHTLWSGGQDQGYESSSSG----LGTVFNSP--VSQQTRRKWPIKRLTYWRTESEEEN---ACVDEQDGLGACFKQVKYIYLSLESDDDDDDDDD-----DDDSVLRSLSKKRKVSDNVPWIPRTGEIQTLLEQDHPVLEGTRVTSIEIGLATAATKLSQQVNN-----MKLTLISPGKKTASKQRQSDLN-------------------------------PCPQTSAFLLLDP-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CH95-1", "uniprot_id": "PHF8_DANRE", "id": "P0CH95-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVP-----VYCLCRLPYDVTRFMIECDVCQDWFHGSCVGVEEDKAAEIDLYHCPNCQV---THGPSVMRKRRGAVKHADVGLGRDSGRPVKTGSAQFVRELRCRTFPSADEVLLKPTGAQLTVEFLEE----------------RSFSVPVLVLRKDGLGMNLPPS-----SFSVTDVEHYIGTEKEIDVIDVSRQADLKMKLGEFVEYYNSP---NRDRVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEES------------IFERPNVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLRGEKIFYLIRPTAANLSLFERWSSSSNQNELFFGDQVDMCYKCSVKQGNTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIDMQLRAYEIEKRLSTADLFKFPNFETVCWYVGKHLLDTFRGLRENRRHPAT--------------------------------------------------------------------------------------------------------------------------------------------------YLVHGAKALNNAFRGWTRKESLGEHEQEIPDTIKTQQ--------LVKDLAKEIRLVEDIFQQNIGRSGTPFGG------------------SQGLP--------SPHPKAQLNTP----------------------------LTF-SQHLSKKRGPK--------------------PKEAFGGGGVGPPGAKKKSQKGKEIKTEAG------ELDLLEIHTKHTLKKFQPGCKV--------------KKSKLELP-DDCLDDFEEKINKS------KLKLVLTNG-----KLQGKKGRAGSANGAGSSLQQ---------------------------------------FQPHMATLSDFDSED-ELQIDETPPPRRRPSL-----------------------------------------------------PSKK---KLAGLPRKLPRAKPCSDPHRIREPG---EVDFDIEEDYTTDEEMLT----MQGVKGGAGGILDLLKASKQVA-------------------------------------------------------------------------------------GLDSALSEEAPASPS-TRDAIQGMLSMAN-------------------------------------PPSSSSSSSSSSPLSISGGGEMMGLMKEKGGREGWMSGVKKSERKAVFQRPGKRPIKRPARHLSDDES-------LDEQETLGTCFKDSDYVYPSLESDEED-------------HVSKSKMKRKRNWDDTPWSPKARVTPTLPKQERPVREGARVASVETGLAAAAAKLAQQEQQKTITKRKYTKKKTPQEKVHSTVAQLQHQ----------------------PDSAPVSPPLPSEPPVDCIVEERRVEVYSASLLDHEYTAGPGPFSPGGP-RGSGAMAPGVFLTSRRPSLSPQNSSSYSPSAPSPGGLVTPTSAGACQGKRPKKGLATAKQRLGKILKIHRNG----------------------KLLL----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WTU0-1", "uniprot_id": "PHF2_MOUSE", "id": "Q9WTU0-1", "name": "Lysine-specific demethylase PHF2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVP-----VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEK---THGKSTLKKKRTWHKHGPGP--TPDVKPVQNGSQLFIKELRSRTFPSAEDVVSRVPGSQLTVGYMEE----------------HGFTEPILVPKKDGLGLAVPAP-----TFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYST---NRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDA------------LLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASANISLYERWRSASNHSEMFFADQVDRCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPP--------------------------------------------------------------------------------------------------------------------------------------------------HLVQGAKILNGAFRSWTKKQALAEHEDELPEHFRPSQ--------LIKDLAKEIRLSENASKTVRPEVNAAASSDEVCDGDR---------EKEEPPSPVETTPPRSLLEKVSKKK--TSKTVKMPKPSKIPKPPKSPKPP---KTLKLKDGSKKKGKKCKESASP--TIPNLDLLEAHTKEALTKMEPPKKGKTPKSVLSVPNKDTVHTQNDMERLEIREQTKSKSEAKWKYKNSK--------------PDSLLKMEEEQRLEKSPLAGNKD------KFSFSFSNRKLLGSKALRPPSSPGVFGALQSFKED---------------------------------------KAKPVRDEYEYVSDDGELKIDEFPIRRKKSAP-----------------------------------------------------KRDLSFLLDKKEALLMPTSKPKLDSAVYKSDDSSDEGSLHIDTDTKP----GRNAKVKKESGSSAAGILDLLQASEEVG-------------------------------------------------------------------------------------ALEYNPNSQPPASPS-TQEAIQGMLSMAN-------------------------------------LQASD-----SCLQTTWGTGQAKGGSLAAHG-------ARK-----IGGGN-KGTGKRLLKRTAKN-SVD-LEDYEE-QDHLDACFKDSDYVYPSLESDEDN-------------PVFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQK-NRKKKNTKRKPAPNTASPSISTSASASTGTTSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAG-TFSGSQAGRASQPMAPGVFLTQRRPSASS--PNN-----------------TAAKGKRTKKGMATAKQRLGKILKIHRNG----------------------KLLL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVJ1-1", "uniprot_id": "A0A8I5ZVJ1_RAT", "id": "A0A8I5ZVJ1-1", "name": "Lysine-specific demethylase PHF2", "aln": "MGVRLSGPGRGGRSPCPSHFGVRRKLRPRSCFWLRQGCSGCVHVVRGRGLRGWSLLASRGHPLPRGSPRAQLLAPPGPRAAHLLPRPAFPAAGAGPRPAGGGGATRGADVAAARRPGVPSVGPRLPARHPRASIRFVSRARQGPPRTLSPAPRGPAGGSRRGPSSPRRHCVDAPGRERARGPCRAPPAPSAPAAAPAPAAPAALAARPPARPGPTRAAQRRGERRRGNMATVP-----VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEK---THGKSTLKKKRTWHKHGPGQ--TPDMKPVQNGSQLFIKELRSRTFPSAEDVVSRVPGSQLTVGYMEE----------------HGFTEPILVPKKDGLGLAVPAP-----TFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYST---NRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDA------------LLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASANLSLYECWRSASNHSEMFFADQVDKCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPP--------------------------------------------------------------------------------------------------------------------------------------------------HLVQGAKILNGAFRSWTKKQALAEHEDELPEHFRPSQ--------LIKDLAKEIRLSENASKTVRPEVNAVASSDEVCDGDR---------EKEEPPSPIESTPPRSLLEKVSKKK--TSKTVKMPKPSKTPKPPKPPKPP---KTLKLKDGSKKKGKKCKESASP--TIPNLDLLEAHTKEALTKMEPPKKGKTPKSVLSVPNKDTVHTQNDVERLEIREQTKSKSEAKWKYKNSK--------------PDSLLRMEEEQRLEKSPLAGNKD------KFSFSFSNRKLLGSKPLRPPSSPGVFGTLQSFKED---------------------------------------KAKPVRDEYEYVSDDGELKIDEFPIRRKKNPP-----------------------------------------------------KRDLSFLLDKKETLLIPTSKPKLDSTAYKSDDSSDEGSLHIDTDTKP----SRNAKVKKESGSSAAGILDLLQASEEVG-------------------------------------------------------------------------------------ALEYNPNSQPPASPS-TQEAIQGMLSMAN-------------------------------------LQASD-----SCLQTTWGTGQAKGGSLAAHG-------ARK-----NGGSS-KGTGKRLLKRTAKN-SVD-LEDYEE-QDHLDACFKDSDYVYPSLESDEDN-------------PVFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQK-NRKKKNTKRKPTPNTASPSVSTSASASTGTTSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSGLADHEYTAAG-TFAGAQAGRASQPMAPGVFLTQRRPSASS--PNN-----------------TAAKGKRTKKGMATAKQRLGKILKIHRNG----------------------KLLL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75151-1", "uniprot_id": "PHF2_HUMAN", "id": "O75151-1", "name": "Lysine-specific demethylase PHF2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVP-----VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEK---THGKSTLKKKRTWHKHGPGQ--APDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEE----------------HGFTEPILVPKKDGLGLAVPAP-----TFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYST---NRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDA------------LLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPP--------------------------------------------------------------------------------------------------------------------------------------------------HLVQGAKILNGAFRSWTKKQALAEHEDELPEHFKPSQ--------LIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDR---------EKEEPPSPIEATPPQSLLEKVSKKK--TPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASP--TIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEAKWKYKNSK--------------PDSLLKMEEEQKLEKSPLAGNKDN-----KFSFSFSNKKLLGSKALRPPTSPGVFGALQNFKED---------------------------------------KPKPVRDEYEYVSDDGELKIDEFPIRRKKNAP-----------------------------------------------------KRDLSFLLDKKAVLPTPVTKPKLDSAAYKSDDSSDEGSLHIDTDTKP----GRNARVKKESGSSAAGILDLLQASEEVG-------------------------------------------------------------------------------------ALEYNPSSQPPASPS-TQEAIQGMLSMAN-------------------------------------LQASD-----SCLQTTWGAGQAKGSSLAAHG-------ARK-----NGGGSGKSAGKRLLKRAAKN-SVD-LDDYEEEQDHLDACFKDSDYVYPSLESDEDN-------------PIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQK-SKKKKSAKRKLTPNTTSPSTSTSISAGT-------TSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAG-TFTGAQAGRTSQPMAPGVFLTQRRPSASS--PNNN----------------TAAKGKRTKKGMATAKQRLGKILKIHRNG----------------------KLLL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P949-1", "uniprot_id": "PHF2_DANRE", "id": "Q6P949-1", "name": "Lysine-specific demethylase phf2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVP-----VYCICRLPYDVTQFMIECDACKDWFHGSCVGVDEDEAPDIDIYHCPNCEK---THGKSTLKKKKSWNKHDTGQ--SGDVRPVQNGSQVFIKELRSRTFPSSEDVVVKLSGSQLTLEYLEE----------------NGFNEPILIQKKDGLGMAMPAP-----TFYVSDVENYVGPDVLVDVVDVTKQTDSKMKLKEFVDYYYST---NRKKVLNVINLEFSDARMANIVESPQIVRKLSWVENYWPDDA------------LLGKPKVSKYCLICVKDSYTDFHIECGGASVWYHVLKGEKIFFLIKPTSANLSLYERWRSSSNHSEMFFADQVDKCYKCTLKQGQTLFIPSGWINAILTPVDCLAFSGHFVHSLSVEMQMRAYEVEKRLKVASLTPFSNFETACWYVGKYYLEQFKGLHKANKQPPP--------------------------------------------------------------------------------------------------------------------------------------------------YLVHGAKIVNGAFRSWTKKQALLEHEDELPENMKPAQ--------LIKDLAKEIRIAEVKQVVSDSQNATKAIKSEPSNSKP---------PAEEPPSALSEPEEPMSPAHVSSPSGDKPARKKVPKPPKMPKAPKPPKEP------KIKEGGKKKAKKVKEGVIPEKKPSSLAALESHAKDILNKMDQPKK--LIKTGMSIMEKETNKPNDVKKFEMIREHNKNKTESKWKYKNSK--------------PDSLLKMEEEHKFDKSLLS-HKDN-----KFAFSLSNKKLLGSKMLKTQTNSSVFGSIQNIKEE---------------------------------------KPKPVRDEYEYVSDEGELKIEEFPIRRKKNAV-----------------------------------------------------KREFSFLSNIKEPIQ-PSKKPKLPPSDMKSPDTSDEESLHIDTEAKTDV-KGRNSKVSKKKGGSSAGILDLLQASKQVG-------------------------------------------------------------------------------------GIDYSNNSQPPASPS-TQEAIQGMLSMAN-------------------------------------LQSSD-----SCLQPFWSNSQAKNNSHSSAA-------SKKPSGAAGAGGNSKRPAKRLPKKTQKSSSVDSSDMFDDDQDHLEACFKDSDYVYPSLESEEDN-------------PIFKSRSKKRKNTDDTPYSPTARVGPTVPRQERPAREGARVASIETGLAAAAAKLSHQEEQK-IKKKKKSAKK-----------------------------------------KPIVAEESHKLSHDSSSPEPTPDSESN-MADHEYSTG----TGKSAG-GSQPMAPGVFLSHRRPSSSSSSQNAS----------------SVLPAKRLKKGMATAKQRLGKILKIHRNG----------------------KLLL----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UWM4-1", "uniprot_id": "KDM7A_MOUSE", "id": "Q3UWM4-1", "name": "Lysine-specific demethylase 7A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAAAAVAAGAAAGAAAAAGSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDCAA---LHGSSLMKKRRNWHRHDYTEV-DDGSKPVQAGTRAFVKELRSRVFPSADEIIVKMHGSQLTQRYLEK----------------HGFDVPIMVPKLDDLGLRLPSP-----AFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNP---DRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDS------------VFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKELKEDGFQPQS--------------------------------------------------------------------------------------------------------------------------------------------------YLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGH--------LIKELSKVIRAIEEENGKPVK--------------------------SQGIPSVCPVSRPSNE--------------------------------------ASPPYHSRRKMRK--------------------LRDHN---------VRTPSNLDILELHTRE------VLKRLEMCPWEED-LLSSKLN-----------------GKFNKHLQPSSTVPEWRAKDN------DLRLLLTNGRIIKDERQLFADRSLYTADSENEEDK---------------------------------------KPTQNANMKTEQSSGREEAESQG----SPKPL-----------------------------------------------------NRIF---TSVRSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRNLLQKSQKPS-------------------------------------------------------------------------------------RQEIPVKRECPTSTSTEEEAIQGMLSMAG-------------------------------------LHYSSCLQRQIQSTDCSGEKNSLQDPSSCHG---------------------SNPEFRQLYRCNKPVEFG-----------YHAKTEDQDLMTSSWNKQFDR----------------TSRFNAQDLSRSQKHIKKESSSEINQKAQSRHCVDSNSSSIQNGKYTLNPSLVS--CQI---------------------------------------------------------------SNGSLSPERPIGETS----------------------FSMPLHP----TKRPASNPPPISN------------------QATKGKRPKKGMATAKQRLGKILKLNRNG--------------------HARFFV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQU2-1", "uniprot_id": "A0A8I6AQU2_RAT", "id": "A0A8I6AQU2-1", "name": "Lysine-specific demethylase 7A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAAAAVAAGAAAGAAAAAVSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPNCAV---LHGSSLMKKRRNWHRHDYTEA-DDGSKPVQAGTRAFVKELRSRVFPSADEVIVKMHGSQLTQRYLEK----------------HGFDVPIMVPKLDDLGLRLPSP-----AFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNP---NRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDS------------VFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKELKEDGFQPQT--------------------------------------------------------------------------------------------------------------------------------------------------YLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGH--------LIKELSKVIRAIEEENGKPVK--------------------------SQGIPSVCPVSRPSND--------------------------------------ASPPGHSRRKMRR--------------------LRDHN---------VRTPSNLDILELHTRE------VLKRLEMCPWEED-ILSSKLN-----------------GKFNKHLQPSSTVPEWRAKDN------DLRLLLTNGRIIKDERQLFADRSLYTADSENEEDK---------------------------------------KPTKKANVKTEQSSGREAAESDG----SPKPL-----------------------------------------------------NRIF---PSVKSELRSRPSEYSDVSDSEDSGPDCTALKINFATEESESSGDEKKHEITSNFKEESDVVRNLLQKSQKPS-------------------------------------------------------------------------------------RNEIPVKRECPTSTSTEEEAIQGMLSMAG-------------------------------------LHYSTCLQ----STDCSGEKNSLQDPSSCHS---------------------SNPEFRQLYRYNKPVEFG-----------YHAKTEDQDLMTSSWNKQFDR----------------TSRFNAQDLSRSQKYIKKESSSEISQKAQSRHCVDSNNSSIQNGKYMLNHSLVS--CQI---------------------------------------------------------------NNGSLSPERPIGETS----------------------FSVPLHP----TKRPASNPPPISN------------------QATKGKRPKKGMATAKQRLGKILKLNRNG--------------------HARFFV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZMT4-1", "uniprot_id": "KDM7A_HUMAN", "id": "Q6ZMT4-1", "name": "Lysine-specific demethylase 7A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAAAAVAAGAAAGAAAAAVSVAAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNCAV---LHGSSLMKKRRNWHRHDYTEI-DDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEK----------------HGFDVPIMVPKLDDLGLRLPSP-----TFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNP---NRPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDDS------------VFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKELREDGFQPQT--------------------------------------------------------------------------------------------------------------------------------------------------YLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGH--------LIKELSKVIRAIEEENGKPVK--------------------------SQGIPIVCPVSRSSNE--------------------------------------ATSPYHSRRKMRK--------------------LRDHN---------VRTPSNLDILELHTRE------VLKRLEMCPWEED-ILSSKLN-----------------GKFNKHLQPSSTVPEWRAKDN------DLRLLLTNGRIIKDERQPFADQSLYTADSENEEDK---------------------------------------RRTKKAKMKIEESSGVEGVEHEE----SQKPL-----------------------------------------------------NGFF---TRVKSELRSRSSGYSDISESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRNFLQKSQKPS-------------------------------------------------------------------------------------RSEIPIKRECPTSTSTEEEAIQGMLSMAG-------------------------------------LHYSTCLQRQIQSTDCSGERNSLQDPSSCHG---------------------SNHEVRQLYRYDKPVECG-----------YHVKTEDPDLRTSSWIKQFD-----------------TSRFHPQDLSRSQKCIRKEGSSEISQRVQSRNYVDSSGSSLQNGKYMQNSNLTSGACQI---------------------------------------------------------------SNGSLSPERPVGETS----------------------FSVPLHP----TKRPASNPPPISN------------------QATKGKRPKKGMATAKQRLGKILKLNRNG--------------------HARFFV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHD1-1", "uniprot_id": "KDM7A_DANRE", "id": "Q5RHD1-1", "name": "Lysine-specific demethylase 7A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAP-----LYCVCRQPYDVNRFMIECDICKDWFHGSCVQVVEHHAADIDVYHCPNCEP---IHGPYMMKKHNNWHRHDYTEP-NDGTRPVQAGTAVFVKELQARSFASG-DILVQMQGNQVTKRFLEK----------------EGFNYPIVVHDLDGLGLKLPPP-----SFSVSDVEHYVGANKVIDVIDVAKQADSKMKLGEFVKYYYQP---ERPKVLNVISLEFSDTRMSNLVVVPDIAQKMSWVENYWPDDS------------FFPKPFVQKYCLMGMKNSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTKANLALYEAWSSSPNQSEVFFGEKVDKCYKCVVKQGTTILLPTGWIHAVLTSQDSMAFGGNFLHNLNIDMQLRCYEMERRLKTPDLFKFPYFEAICWYVAKNLLETLKELRENKCEAQG--------------------------------------------------------------------------------------------------------------------------------------------------FLVNGVKALISSLKMWLRRELTQPNS-EVPDNIRPGH--------LIKALSKEIRHLEDDSNKAVK--------------------------TQGS-AECSLSRSTLEKGDQAQQAA---------------------------RRLQDHHHHRRRHHH--------------------HHHHHHHHHHHHHSRKLPSNLDVLELHTLE------VLKRLEVGQLKEDSAFSSKVN-----------------GKF-KKVCPVPAAAVEASHDN------ALRLVMCNGKIIRERMPITNVAATVNAVEMYHKHR---------------------------------------IKLERIPMCPEEKVKKEKCEDEFGVQCTIKKP-----------------------------------------------------VSQG---ESVQTELRTESPHLAS-SDS-DSKAGDSAEKCSLESESSDGE-DGGSQRDSGTFVEH--------LNSHRHS-------------------------------------------------------------------------------------HHKQALKRERPTSPN-TDCAIQGMLSMAG-------------------------------------LLCP---------QASGGAADILQQR--------------------------------------------------------------------WWASQGNG----------------SSTSSSSDMWDS---------SEPCSAPRSPDAED-----------------------------------------------------------------------------------------GSLGEEYSYRESS----------------------LSPPLHP----SKRHAPNPTPVSN------------------QATKGKRPKKGQATAKQRLGKILKMSRHKGLFLMKPMVFLIPQQGGTPLDPQFLLQSSSICVFPPPLIVSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40034-1", "uniprot_id": "JHD1_YEAST", "id": "P40034-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQDPNICQHCQLKDNPGALIWVKCDSCPQWVHVKCVPLKRIHYSNLTSSEVLSYPNSAKQIKSYRCPNHKEGEYLTAYALITQKGKRQRNKENPEDSHINKRYNFRKKKLLDYIALNEGESKRDKMNHPHKESFMKSFEKWKNGSNIINAADFAEKFDNIDVPYKIIDPLNSGVYVPNVGTDNGCLTVNYITEMIGEDYHVDVMDVQSQMNENWNLGSWNEYFTNTEPDRRDRIRNVISLEVSNIEGLELER-PTAVRQNDLVDKIWSFNGHLEKVNGEKAEENDPKPKVTKYILMSVKDAYTDFHLDFAGTSVYYNVISGQKKFLLFPPTQSNIDKYIEWSLKEDQNSVFLGDILEDGIAMELDAGDLFMIPAGYIHAVYTPVDSLVFGGNFLTIRDLETHLKIVEIEKLTKVPRRFTFPKFDQVMGKLCEYLALDKNKITSDVS------------------------------------------------------------------------------------------------------------------------------------------------------DGDLLSRTTNCAIQSLHAYVIKPEVKYKPLNFTSKKH--------LAKALADLIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. : : : * . . *: :* : * : :* :** *. * . : : .: *: : :: ** .**.*. . * . . *: *. . * * :* *: :...:****:: .*:* :*:: * * * *: * *: : * : .:*:.: : * :.:*:*:* * *. : :.*.*::: .: :: * :. : : ", "identical_positions": 46, "similar_positions": 80, "identity": "2.46%" }, { "cls_id": "homologset.agr.SGD:S000000855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEM8-1", "uniprot_id": "S25A3_MOUSE", "id": "Q8VEM8-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNAPHLQLVHDGLSGPRS----PPAPPRRSRHLAAAAVEE----YSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQT-QPGYANTLREAVPKMYKEEG-LNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------TASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16036-1", "uniprot_id": "S25A3_RAT", "id": "P16036-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNAPHLQLVHD-VSGPRS----PPGPPRRSRHLAAAAVEG----YSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQT-QPGYANTLREAVPKMYKEEG-LNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------TASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00325-1", "uniprot_id": "S25A3_HUMAN", "id": "Q00325-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQ---YSCDYGSGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQT-QPGYANTLRDAAPKMYKEEG-LKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------SASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8E8-1", "uniprot_id": "Q0E8E8_DROME", "id": "Q0E8E8-1", "name": "Phosphate carrier protein, mitochondrial", "aln": "MFSSFFETARNSPFRTPMSMARCDAAAPVVE------PQPVEGRQIAAAATPVANQQDSCEFGSTKYFALCGIGGILSCGTTHTFVVPLDLVKCRLQVDQAKYKNLVHGFKVTVAEEGARGLAKGWFPTLLGYSAQGLCKFGLYELFKVKYAEIIGEENAYLYRTSLYLAASASAEFFADIALAPFEAAKVKIQT-IPGYANNFREAVPKMLKEEG-VNAFYKGLVPLWMRQIPYTMMKFACFERTVELLYKYVVPKPRADCTKGEQLIVTFAAGYIAGVFCAVVSHPADVVVSKLNQAKGA------SAISVAKSLGFSGMWNGLTPRIIMIGTLTALQWFIYDGVKVALGIPRPPPPEMPASLKAKQH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40035-1", "uniprot_id": "PIC2_YEAST", "id": "P40035-1", "name": "Mitochondrial phosphate carrier protein 2", "aln": "----------MESNKQPRK----------------------------------------IQLYTKEFYATCTLGGIIACGPTHSSITPLDLVKCRLQVNPKLYTSNLQGFRKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYEYFKHLYSSWLSPG------VTVYLMASATAEFLADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYS-VLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKINSERKANESMSVASKRIYQKIGFTGLWNGLMVRIVMIGTLTSFQWLIYDSFKAYVGLPTTG----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * : : .:: * :**:::** **: :.********:**: *.. .:** : ::* : : .*: .*::*** ** *:* ** ** *:. :. .::** :**:***:*** *.*:** **: ** * :.*.. :. ** *.* ::*****:.*:* ******* **:.**: *: :*. *:** : : . :*: *:*..**:**::** ****** :** :*. : : :: : : :** *:*:** **:******::**:***..*. . :* . ", "identical_positions": 122, "similar_positions": 97, "identity": "32.71%" }, { "cls_id": "homologset.agr.SGD:S000000856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R5-1", "uniprot_id": "PPR3C_RAT", "id": "Q5U2R5-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHS----------------PPLKSFLGPYNGLQRRHFVN-KPKPLKPCLSVKQEAK-SQKEWKSPHSQA------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSSLK-LHEEKNLVFDFPQPSSDYLSFRDRFQKN-----FVCLENCSLQDRT--VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKNVYGSSDSDTFSFAIDLPRVIPTE-EKIEFCISYHAN--GRVFWDNNEAQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQVPLKTELEPTVFG--SPRLASGLFPEWQSWGRVENLASYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMB3-1", "uniprot_id": "PPR3C_MOUSE", "id": "Q7TMB3-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHS----------------PPLKSFLGPYNGFQRRNFVN-KLKPLKPCLSVKQEAK-SQSEWKSPHNQA------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSSLK-LHEEKNLVFDFPQPSTDYLSFRDRFQKN-----FVCLENCSLQDRT--VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYMKNVYSSSDSDTFSFAIDLPRVIPTE-EKIEFCISYHAN--GRIFWDNNEGQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQGPPKTEIEPTVFG--SPRLASGLFPEWQSWGRVENLTSYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQK1-1", "uniprot_id": "PPR3C_HUMAN", "id": "Q9UQK1-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHS----------------PPVKSFLGPYDEFQRRHFVN-KLKPLKSCLNIKHKAK-SQNDWKCSHNQA------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSALK-HHEEKNLILDFPQPSTDYLSFRSHFQKN-----FVCLENCSLQERT--VTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTE-QKIEFCISYHAN--GQVFWDNNDGQNYRIVHVQWKPDGVQ--TQMAPQDCAFHQTSPKTELESTIFG--SPRLASGLFPEWQSWGRMENLASYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTC2-1", "uniprot_id": "F1QTC2_DANRE", "id": "F1QTC2-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSSTRVLHILSP-PMPGPVMPVDVAVQLYITHS----------------PPLRNFLSSYEDYRTRNLVSNCCKPLRPCLSSRAQLEHSCRSWQNPKSKT------KKKVVFADSKGMSLTAVHVFSTFDNKETATSELQFDLEDLEELKNTLH-INSVQSRILDFLQPAADYLDFRSHLLKN-----LVCLENCTLQERA--LTGTIKVRNLAYEKSVHVRITFDSWKSFEDIECTFMNNVYGCQDTDTFSFAIELPGYVPPQ-NKVEFCISFRTG--EQIYWDNNDGRNYGLISTSWQQNNKLNSSTQTKKSDEFRKKSSKKTQEKGVFKCKSSLQSNGIFPNWQSWGQIAATGPYW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P950-1", "uniprot_id": "PR3CB_DANRE", "id": "Q6P950-1", "name": "Protein phosphatase 1 regulatory subunit 3C-B", "aln": "--------------------------------------------------------MNCTRVLQILNPRPMPSPIMPVDVAMRICLAHS----------------PPLRSFLSSYEDCKSRNLVN-QYKPLRSCISSKTEDDTANITWKSPETKA------KKKVVFADSKGMSLTAVHVFKEFE--EDLMLDLQFELSDLEDAIVGLK-AEKEKNFSLGFPQPAADYLDFRNRLKKN-----LVCLENCIIQERS--VTGTVKVSNVSFEKVVHVRITFDSWKSHTDIPCTYMNNVYGCEDVDTFSFSIDLPSFVAPH-EQVEFCLSYKTH--DMTYWDNNDGKNYKLVHT---ENDSSQASVIQNATTDFKAQGKRPDMEFDQFG--SPRTSSGFFPEWQSWGHIENNTPYW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C767-1", "uniprot_id": "PPR3B_MOUSE", "id": "Q8C767-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MAVDIQYSYSSMAPSLRRERFTFKISPKLS----------------KPLRPCI---------------------QLGSKDEAS-GMVAPAVQEKKV------KKRVSFADNQGLALTMVKVFSEFD----DPLDIPFNITELLDNIVSLT-TAESESFVLDFPQPSADYLDFRNRLQTN-----HVCLENCVLKDKA--IAGTVKVQNLAFEKVVKIRMTFDTWKSFTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVCYECN--GQAYWDSNKGKNYRITRAELRSSP----GKIEPYN------GPDFGISFDQFG--SPRCSFGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IN01-1", "uniprot_id": "PPR3B_RAT", "id": "Q6IN01-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MAVDIEYSYSSMAPSLRRERFTFKISPKLN----------------KPLRPCI---------------------QLGSKDEAG-RMVAPTVQEKKV------KKRVSFADNQGLALTMVKVFSEFD----DPLDIPFNITELLDNIVSLT-TAESESFVLDFPQPSADYLDFRNRLQTN-----HVCLENCVLKEKA--IAGTVKVQNLAFEKVVKIRMTFDTWKSFTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVCYECN--GQSYWDSNKGKNYRITRAELRSTQ----GMTEPYN------GPDFGISFDQFG--SPRCSFGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XI6-1", "uniprot_id": "PPR3B_HUMAN", "id": "Q86XI6-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "----------------------------------------------------------MMAVDIEYRYNCMAPSLRQERFAFKISPKPS----------------KPLRPCI---------------------QLSSKNEAS-GMVAPAVQEKKV------KKRVSFADNQGLALTMVKVFSEFD----DPLDMPFNITELLDNIVSLT-TAESESFVLDFSQPSADYLDFRNRLQAD-----HVCLENCVLKDKA--IAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVYYECN--GQTYWDSNRGKNYRIIRAELKSTQ----GMTKPHS------GPDLGISFDQFG--SPRCSYGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803M0-1", "uniprot_id": "PPR3B_DANRE", "id": "Q803M0-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MPIELA-----MSLYLSSDEFLNPRASKYS----------------RPLQPCLNQCKSS----------KLSFSSLKEQSEFN-GVSRALMIPGRA------KKHVSFADHKGLALTVVKIFSEFD----DPIDIPDNIDNFFTSSLTVS-EGK-DKLTLDFDQPSADYLKFRQRIEND-----HVCLEHCMLKEKS--IMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSH-ERIEFAICYEVN--GDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYS------QSDWDIHFDRYG--SPRCSRGIFPHWPSYVGYEDIGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AJW4-1", "uniprot_id": "A2AJW4_MOUSE", "id": "A2AJW4-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "--------------------------------------------------------MSKGSGSAPLPSTPGSRKLVPRSLSCLSDMDR------RPCRPPG--------------CDPRLRPIIQRRSRSLPTSPERRAKAAGAPGAACGAGCNR------QVRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQD-LEFTLQCLVPDFSPPIETPGFGERLARQ-----LVCLERVTCSDLG--ISGTVRVRNVAFEKQVTVRYTFSGWRSAHEAVARWRGPAGAEGTEDIFAFGFPVPPFLLELGSQVHFALRYGVA--GAEYWDNNDGRDYSLTCRS-------------------------------------HALHMPRGECEESWIHFI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95685-1", "uniprot_id": "PPR3D_HUMAN", "id": "O95685-1", "name": "Protein phosphatase 1 regulatory subunit 3D", "aln": "--------------------------------------------------------MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQ------KLRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQD-LEFTLHCLVPDFPPPVEAADFGERLQRQ-----LVCLERVTCSDLG--ISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVA--GAEYWDNNDHRDYSLTCRN-------------------------------------HALHMPRGECEESWIHFI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MR9-1", "uniprot_id": "PPR3A_MOUSE", "id": "Q99MR9-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "-----------------------------------------------------------------MEPAEEPGQISKDNFLEVPNLSDS-------------------------VCEDEEVKATFKPG--FSPQPSRRGSGS-SEDMYLDTPTSA------SRRVSFADSLGFSLVSVKEFDCWELP----------SVSTDFDLSGDV-FHTDEYVLSPLFDLPSSKEKLMEQLQVQ-----KAVLESAEHLPGS-SMKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEY-VPNSCDGETDQFSFKISLVPPYQKEGGKVEFCIRYETS--AGTFWSNNNGTNYILVCQKKRKEPEPVKPLEEAPSRQIKGCLKVKSRSKEEPLLAPEENKFETLKFTESYIPTIICSHEDKDDLGANHPNVDDINKKHDEHNGKELDLMINQRLITS-----QDEKNTFATDTVNFTNKAEGSEKKQAYHEINTDLFMGPLSPSLSAESSLKRDFYHSRSSSPGNEYGHPHSEEIISDMGEKGPSLGDTSSDELMQLELCSKEDLDDNANPANGSGRV---CSSFDQRMACGLKNNEAG------IKKTGIQDYKYSHGDSTKLEESN---ASSRDDYAKVDNKKEKQTCLGVNENPSKNFQSVFQTQEGHMGYPKISTEGDKANNQDLTSLLSKDITANTWAVTVDPCPSTNAKRSWREVGS----------GSNLEPGTSDLSSPRNFSPLTDDHLFQADRENSDSSNPENQNMNTRHRKKWNVLETQSETSETESDIAKHTKEQAEYKDMWEKTDNSRNLKATPTEHLFTCRETECYGLSSLADHGITEKAQAVTAYIIKTTLESTPESASARGKAIIAKLPQETAGNDRPIEVKETAFDPHEGRKDDSHYSLCHGDTAGVIHDNDFERESHLDICNLRVDEMKKEKTTSTCFPQKTYDKEKHGIGSVTSIDEPSQVITGNQKATSKLDLHLGVLPTDRAIFQANADLELLQELSRRTDFNAVP-SAFNSDTASASRDSSQVYRHCSKKSVPS----YGEEKAVTNTTLQSIPTKSEYNWHPESEVLG-----HAMSKPEDVFKSSEIMKSGSGGERGGGPILQQKEGSLENSQGPMFFTNEPLENLDEASSENEGLMHSGQSQCYLGDKGLVSSASATVSTQELEAQGRESLLSISTNSKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16821-1", "uniprot_id": "PPR3A_HUMAN", "id": "Q16821-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "-----------------------------------------------------------------MEPSEVPSQISKDNFLEVPNLSDS-------------------------LCEDEEV--TFQPG--FSPQPSRRGSDS-SEDIYLDTPSSG------TRRVSFADSFGFNLVSVKEFDCWELP----------SASTTFDLGTDI-FHTEEYVLAPLFDLPSSKEDLMQQLQIQ-----KAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEY-VPNSCDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETS--VGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKS-SKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVE-EKSGGINSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKAT-TEELFTCQETVCCELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFLLFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUF3-1", "uniprot_id": "Q9VUF3_DROME", "id": "Q9VUF3-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MISHSPPIFSHSPPVSFLADFMSGHPRQSLNYNDEPNRASRYCRPQVITLASKAMVNNASAAVQGQGPSQQKAGATPLGVGSRSGRSYLER-----MASAPLLTNQPKSCLSRKSCLHKSQNTTASSADLSPTDTDVADSASHSCICSKDSDSNGEVSRGPKKHVIFADDEGLSLTEVRVMSEPS-----NVPPYWSMKFLEQITQGLVSPHPPDQWTVDFKQPASDYLSFRQKIERD-----FVSLENVIVKDEESIVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYARAYGPATCAHVVFDTFSFKITLPPSSKRLEFCICYRTN--ETEYWDNNDGKNYTISKRSPFYYN-----ALSPYD-------KGQNRNSSQQIRSTLTDALAKVQDQNGWHQEPHTPYW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B1R9-1", "uniprot_id": "A0A8M2B1R9_DANRE", "id": "A0A8M2B1R9-1", "name": "", "aln": "---------------------------------------------------------MSITKQYVLSSNPFPEHVMPVDLSMNAQITSFAS-------------------------RSSTDRHRFSPSSPTSSLSSSSSGGSLSSYSSGTSTLRK------KKQVVFADSKGLNLVSIRIFIADP----SEMETEEAAQSEELVKPRTPVQNLRFKVKLGFSQPVPD----IASLMKN-----FVQLESCRVKGRL--LSGTVRVFNLMLDKTVFVRITYDSWRSHRDIPCINVREPHLSFQTALFEFMEYLPSDLDPK-ELLEFFVVFCPGNVKKQYVDDNEGKQYQLHVENVAAESRLGSSESRLAPLEHRLVSSESRLSPSKHRLVTTEHRRAQSEAHRLAIESRTVTLRRRSFITPSPQCYSAWPAERVLDQQRMTNMTCRASPDHRVSKNFRSTSVTQVIC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40036-1", "uniprot_id": "GIP2_YEAST", "id": "P40036-1", "name": "GLC7-interacting protein 2", "aln": "--------------------------------------------------------MYIKAEQKPQQFERKNEKLDRNKNQQLPDLETDFKG----------------YRVNSDLYNKERDGSTEETLNSLKFLHKPQRVTQMRANRFPEEEVQRN---TDLNKRIFSAGNDENVDNESGWSKIAAAKNHTSVESLNGSTRPPFKIELPPLSPKSTVPKSFQAEYPEAKSPGNDMNFEYDEEILIPFAPPVYKKSGELLKSSLKRRSKSLPTTPGIRSGNGVQARDGSPMLIRSKSVHFDQAAPVKYFAEDESPINVNKTEQHDNCLSFKHKPVNLMVDPEEETKMLSSGLETTSIDDDLTTVAPKGFAHPAKISNPNNGKGTNNTKLRKSKRFQNLLKNRTDMPPSKSNKKFVNGGGAHEISDRNSKNYHVVGLYSKNFPILSNKNPKSLKLNIFINLSQNKKVFLQELSLYIHRDNNYFSNSSSFYNIPNSHNGNDCNGVAKGYNAGCTRLIAGRILVKNIFYDKRVVVRYTWDSWRTTHEVECVYISDGDGILPGTNMDIFHFIIDDVSKVDPRGKLEFCIHYSTRNDYEREEYWDNNNGNNYKVDVVMDGFNDPFAAAA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . : . : : : : . :: . . :* . . . : : .: ", "identical_positions": 2, "similar_positions": 22, "identity": "0.16%" }, { "cls_id": "homologset.agr.SGD:S000000859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52759-1", "uniprot_id": "RIDA_RAT", "id": "P52759-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "MSSIIRKVISTSKAPAAIGAYSQAVLVDRTIYVSGQIGMDPSSGQLVPGGVAEEAKQALKNLGEILKAAGCDFTNVVKTTVLLADINDFGTVNEIYKTYFQGNLPARAAYQVAALPKGSRIEIEAIAVQGPFTTAGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52760-1", "uniprot_id": "RIDA_MOUSE", "id": "P52760-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "MSSIIRKVISTTKAPAAIGPYSQAVQVDRTIYISGQVGLDPSSGQLVPGGVVEEAKQALKNLGEILKAAGCDFNNVVKTTVLLADMNDFGTVNEIYKTYFQGSLPARAAYQVAALPRGSRVEIEAIAVQGPFIKA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52758-1", "uniprot_id": "RIDA_HUMAN", "id": "P52758-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "MSSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3W0-1", "uniprot_id": "UK114_DROME", "id": "Q9V3W0-1", "name": "RutC family protein UK114", "aln": "MSTIVRKLISTANAAKPVAPYNQAVVADRTVYVSGCLGLDKDTMKLVPGGPTEQAQKALENLEAVLKAADSGVDKVIKNTVFLKDLNDFGAVNEVYKRVFNKDFPARSCFQVAKLPMDALVEIECIALTGSVETKTVQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40037-1", "uniprot_id": "HMF1_YEAST", "id": "P40037-1", "name": "Protein HMF1", "aln": "MVTTLTPVICES-APAAAASYSHAMKVNNLIFLSGQIPVTPDN-KLVEGSIADKAEQVIQNIKNVLEASNSSLDRVVKVNIFLADINHFAEFNSVYAKYFNTHKPARSCVAVAALPLGVDMEMEAIAAERD-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : :*. : *. . ..*.:*: .:. :::** : : .. :** *. .::*::.::*: :*:*:.... .*:* .::* *:*.* .*.:* *: ***:. ** ** . :*:*.:* ", "identical_positions": 33, "similar_positions": 58, "identity": "23.91%" }, { "cls_id": "homologset.agr.SGD:S000000860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UWS5-1", "uniprot_id": "PT117_HUMAN", "id": "Q6UWS5-1", "name": "Protein PET117 homolog, mitochondrial", "aln": "MSRSSKVVLGLSVLLTAATVAGVHVKQQWDQQRLRDGVIRDIERQIRKK----ENIRLLGEQIILTEQLEA-----------------------EREK-----------------MLLAKGSQKS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJF2-1", "uniprot_id": "PT117_MOUSE", "id": "P0DJF2-1", "name": "Protein PET117 homolog, mitochondrial", "aln": "MSRSSKAVLGLSVLLTAATVAGVHLKQRQDRQRLRDGVIRDIERQNQKK----ENIRLLGEQIILTKQLEA-----------------------EREK-----------------MLE-KGSQNT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VPN3-1", "uniprot_id": "Q9VPN3_DROME", "id": "Q9VPN3-1", "name": "Protein PET117 homolog, mitochondrial", "aln": "MSTASRVTLGLAVSISTAIIGYVHYKQSADRLRLHDGVLRDVEQQQRRKH---ENTYTLQQQIDMTKQLKAREASSNSSDTPVPPSTHRAQSNLQAEKPAVQNEGEAFRGVPQGGTTNHDGSPPTDIA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02771-1", "uniprot_id": "PT117_YEAST", "id": "Q02771-1", "name": "Protein PET117, mitochondrial", "aln": "MSRASKITFAASCLITAATVVGVHYVQEMERETLHQGPIKDAKRVEEKRLRKTNGVASLDPTKERKRYFNMS----------------------EHEEQKELRKKYETMQPLSGEVVTKDGEVVKESKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*: .:. : :::* : ** * :: *::* ::* :: .:: :. * .. :: : *: .*. . ", "identical_positions": 13, "similar_positions": 32, "identity": "10.08%" }, { "cls_id": "homologset.agr.SGD:S000000863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6R7-1", "uniprot_id": "G3V6R7_RAT", "id": "G3V6R7-1", "name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "aln": "MLSKCLQHFLKA---HLYPASYC-WLISKHKFSGSVPAAGSRRRVVITGIGLVTPLGVGTQLVWDRLLRGESGIVSVVG-----DEYKSIPCSVAAFVPRGSDKGQFNEQN------FVSKSDAKSMSSPTIMAVGAAELALKDSGWYPK-------LEADQVATGVAIGMGMVPLEVVSETALMFQTKGYSKVSPFFVPKILINMAAGQVSIRYKLKGPNHSVSTACTTGAHAVGDSFRLIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NPDPKLACRPFHPERDGFVMGEGAAVLVLEEHEHAVQRGARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAAVKDAGVSPDQISYVNAHATSTPLGDAAENRAIKRLFR---DHARALAISSTKGATGHLLGAAGAVEAAFTALACYHHKLPPTLNLD--CTEAEFDLNYVPLEAQEWKTEG-RCIGLTNSFGFGGTNATLCIAGI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D404-1", "uniprot_id": "OXSM_MOUSE", "id": "Q9D404-1", "name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "aln": "MLSKCLQHFLKATISHPYPASYS-WLISKHRFYGTVPAAMLRRRVVITGIGLVTPLGVGTQLVWDRLLRGESGIVSVVG-----DEYKNIPCSVAAYVPRGPHEGQFNEEN------FVSKSDAKSMSSSTIMAVGAAELALKDSGWHPK-------READQVATGVAIGMGMVPLEVISETALLFQTKGYNKVSPFFVPKILINMAAGQVSIRYKLKGPNHSVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSS--NPDPKLACRPFHPERDGFVMGEGAAVLVLEEHEHAVQRGARIYAEILGYGLSGDAGHITAPDPEGEGALRCMAAAVKDAGVSPEQISYVNAHATSTPLGDAAENRAIKRLFR---DHACALAISSTKGATGHLLGAAGAVEATFTALACYHQKLPPTLNLD--CTEPEFDLNYVPLESQEWKAEG-RCIGLTNSFGFGGTNATLCIAGM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWU1-1", "uniprot_id": "OXSM_HUMAN", "id": "Q9NWU1-1", "name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "aln": "-MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVG-----EEYKSIPCSVAAYVPRGSDEGQFNEQN------FVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQ-------SEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFK---DHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLD--CSEPEFDLNYVPLKAQEWKTEK-RFIGLTNSFGFGGTNATLCIAGL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNF5-1", "uniprot_id": "Q9VNF5_DROME", "id": "Q9VNF5-1", "name": "3-oxoacyl-[acyl-carrier-protein] synthase", "aln": "----------------MRVLGKCTVLVRQTR---SLSTPSGRRRVVVTGSGAVTPLGNNGPDSWRRILAGESAISRLS------AEFKGLPCQVAAQIPRE----NLQLDQ------HLTKSDIKLMSPATQLAVLAAEEALSTGKLCPKQ-----LSEEELERFGVCVGMGMFDLAEVYG-AWNQLQRGYNRVSPFFVPRLLPSMACGHISMRHGLRGPNHSVSTACATGAHALGDAMRFIRSGDADLMLAGSGEACIDPLSIAGFCRLRALSTAFNDNPAVASRPFDKSRDGFVMGEGAAVLLLEELEHARARGAPILAEILGYGLSGDAYHITSPSDDGAGATLAMKRAIQDAGIAPEDVTYVNAHATSTPTGDRIESHAIGRVFG---AHTPQVRVSSTKGAHGHLLGSSGNLEALFVVLACANNKLPPSINIE--HLD--VDVN-VVTKATDWSADQKRRVALKNSFGFGGTNASLCIASYI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39525-1", "uniprot_id": "CEM1_YEAST", "id": "P39525-1", "name": "3-oxoacyl-[acyl-carrier-protein] synthase homolog", "aln": "----------------------------------------MSRRVVITGLGCVTPLGRSLSESWGNLLSSKNGLTPITSLPNYNEDYKLREKSIPSTITVGKIPENFQNENSAINKLLFTSQDERRTSSFIKLALRTTYEALHNAGLLNPNDITINTSLCNLDHFGCLIGSGIGSIQDIYQTSLQFHND-NKRINPYFVPKILTNMAAGNVSIKFNLRGLSHSVSTACATGNNSIGDAFNFIRLGMQDICVAGASETSLHPLSLAGFIRAKSITT------NGISRPFDTQRSGFVLGEGCGMIVMESLEHAQKRNANIISELVGYGLSSDACHITSPPADGNGAKRAIEMALKMARLEPTDVDYVNAHATSTLLGDKAECLAVASALLPGRSKSKPLYISSNKGAIGHLLGAAGAVESIFTICSLKDDKMPHTLNLDNVLTLENNEADKLHFIRDKPIVGANPKYALCNSFGFGGVNTSLLFKKWEGS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:** * ***** . * .:: .:..: : ::* .:.: :. ::: :: .:..* : *. :*: :: *: . : * :* *: : : : .::.*:***::* .**.*::*::. *:* .*:*****:** :::**::.:* * *: :**. ::.: ***:*** * ::::: .***. .*.***:***..::::*. *** * * * :*::*****.** ***:* :* ** .: *:: * : * :: *:******* ** * *: : :: : :**.*** *****::* :*: *. : .*:* ::*:: : : : . . .* *******.*::* : ", "identical_positions": 127, "similar_positions": 135, "identity": "25.97%" }, { "cls_id": "homologset.agr.SGD:S000000868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VPX2-1", "uniprot_id": "F8VPX2_MOUSE", "id": "F8VPX2-1", "name": "F-box/WD repeat-containing protein 9", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLSSGRSGDPRSCEE-------------------------------ESDPEPDPDPDTQAEAYVARVLTPPKLGLTPRR---------------------------------------------------------------SSLQSMFSASLGVPERKAASKVPAVRLPG-------------------------------------------------LLSLPPELLLEICAYLDARVVLQVLPCVCQALHDLVRDRVTWRLRAQRRVRAPYPVVEEEN---------FDWPAACIELEQHLARWAEDGQRTEYFCLADGHFASIDAVLLLQGGALCLSGSRDRNVNLWDLR----------HLGKDPSRVLVKALGTQGNSTHKGWVWSLAA-------------------QDHRVCSGSWDSTVKLWDMAADGQQFGEIKGKAAVLCLSYQPDILVTGTYDKKVTIYDPRAGLALVKSRRLHSSAVLAVLADDRHVISGSEDHSLVVFDRRAN----------SVLQRLQLDSYLLCMSYQEP--QLWAGDNQGLLHVFANRDGCFQLVRSFDVGHQSQITGIKHSLGTLYTTSTDKTIRVHVPTDP--PRTICTRSHHNVLNGICAEGNVVVAASGGLSLEVWRLLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAM1-1", "uniprot_id": "F1MAM1_RAT", "id": "F1MAM1-1", "name": "F-box/WD repeat-containing protein 9", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELPSGQCGNPRSCED-------------------------------ESDPEPEPDPDAQAEAYVARVLTPPKPGMTPRR---------------------------------------------------------------SSLQSMFSASLGMPERKDASKVPAVSLPG-------------------------------------------------LLSLPPELLLEICAYLDARVVLHVLPCVCQALHNLVRDRVTWRLRAQRRVRSPYPVVEEEN---------FDWPAACIELEQHLARWAEDGQRTEYFCLADGHFASIDAVLLLQGGTLCLSGSRDRNVNLWDLR----------HLGKEPSRVLVKALGTQGNSTHKGWVWSLAA-------------------QDHRVCSGSWDSTVKLWDMAADGQQFGEIKGKAAVLCLSYQPDILVTGTYDKKVTIYDPRAGLTLVKSRRLHSSAVLAVLADDRHIISGSEDHSLVVFDRRAN----------SVLQRLQLDSYLLCMSYQEP--QLWAGDNQGLLHVFANQDGCFQLVRTFDVGHQSQITGIKHSLGTLYTTSTDKTIRVHVPTDP--PKTICTRRHHNVLNGICAEGNIVVAASGGLSLEVWRLLA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XUX1-3", "uniprot_id": "FBXW9_HUMAN", "id": "Q5XUX1-3", "name": "F-box/WD repeat-containing protein 9", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELPLGRCDDSRTWDD-------------------------------DSDPESETDPDAQAKAYVARVLSPPKSGLAFSR---------------------------------------------------------------PSQLSTPAASPSASEPRAASRVSAVSEPG-------------------------------------------------LLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRALRRVRAPYPVVEEKN---------FDWPAACIALEQHLSRWAEDGRWVEYFCLAEGHVASVDSVLLLQGGSLCLSGSRDRNVNLWDLR----------QLGTESNQVLIKTLGTKRNSTHEGWVWSLAA-------------------QDHRVCSGSWDSTVKLWDMAADGQQFGEIKASSAVLCLSYLPDILVTGTYDKKVTIYDPRAGPALLKHQQLHSRPVLTLLADDRHIISGSEDHTLVVVDRRAN----------SVLQRLQLDSYLLCMSYQEP--QLWAGDNQGLLHVFANRNGCFQLIRSFDVGHSFPITGIQYSVGALYTTSTDKTIRVHVPTDP--PRTICTRRHDNGLNRVCAEGNLVVAGSGDLSLEVWRLQA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZF4-1", "uniprot_id": "FBXW7_DROME", "id": "Q9VZF4-1", "name": "F-box/WD repeat-containing protein 7", "aln": "MERGCPAASSESVTSAGERTQSAVTSSTSTWVKSQASTSRKTEASEESGLGAVDAEVGAGREAFVSMSTLREDVEDVCVSSNSQHGFAVVLDDESSTFEISSSNSLPTSAGAASTVGVVAVDDSSSTDTLNGGHPDLGHPASSEHSRQGFFNEDNEDPPVVCLINDDDDDEEPEPEEDDEEELIEDEDEDAVDIVTGAISCPNTSQLALADGTIMAADGSKIFLETPVVEEAQPHPGQVVTTGSQSELTGKPKRLSDEFLLGEEDQAENLALGRCIKSEPVNPVDDNPSEGDDGATCFSLHDRLMSVRLKQMSLTANTVSNPSPAASANAAAPEEASTSNSSSTSSSALSRADIESMDLIERRDFETEQRLTGGIILRTSSMVSQNKLNLSLIKSMAGGSKAANGSGTANSDDWPSSSNGRTVSSDSKYTYKDLSTTPTSSRKYTNSRLSKSTAKLNLGSSLGASSCSQHRSGSSSTSKSMESSTSCTGAARTDVYTNTNSNDYPSLAPTTSGSSTSGGSCQQDQEENVSASVSYSSVGSQTSQESGCSRTTAINPTAACSTGSACLGDSQASTSASTSSGAGASNRCQYATTSTTKAARQVNASAQTQERFLTRSNPPAASGAGSVGANPTASVRQRRNGSSDVVHLEVVVEEGAGGGDGGVVEPGDFSAEEPWANCDEENNCSDLEEICTCQNGNGSSYGGSNASLSETFDMDAMDPDEPISLSLSSASAGFTEYSLTNPSSLMSHQRKRKFNEGRLLDGGDYSVTISSSGEVGGPGSGVSDNCRKRIAYDFASTPRSSQHLGPTAVLSVTPSSHLTSSTPGSALGRRTPRSVPSRDNPPPELQHWLAQFQRWSHVERLLALDRLIDHCDPSQVRHMMKVIEPQFQRDFISLLPRELALFVLSYLEPKDLLRAA-QTCRSWRFLCDDNLLWKEKCRKAQILAEPRSDRPKRGRDGNMPPIASPWKAAYMRQHIIEMNWRSRPVRKPKVLKGHDDHVITCLQFSG-NRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPER-QECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWRIRANDTKLICAVGSRNGTEETKLMVLDFDVEGACVKCS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40042-1", "uniprot_id": "RRT13_YEAST", "id": "P40042-1", "name": "Regulator of rDNA transcription protein 13", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLEN----------------------------------------------------------IRNNGECSYATNSASPCAKILG--AMYTLRGHRALVGLLGLSDKFLVSASVDGSIRCWDANTYFLKHFFDHTQLNTITALHVSDEVLVSGS-EGLLNIYDLNSG---------------LLVRSDTLSG--ADN---VWNVSFKDNTLVAAVERDKRNLLEILDFS-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .** : : : :*.* * .:.:*. :. * : ::: .: . : * : .::*:.: * : :... : : : :: .. ::*** : : : * .:. : : . * : :* . : . : ::.. ", "identical_positions": 16, "similar_positions": 63, "identity": "1.2%" }, { "cls_id": "homologset.agr.SGD:S000000870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95628-1", "uniprot_id": "CNOT4_HUMAN", "id": "O95628-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYK-LNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNHSAR--------------------------SPFEGAVTESQS-----LFSDNFRHPNPIPSGLPPFPSSPQTSSDWP----------------TAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVT--RKALADLIEKELSVQDQPSLSPTSLQ-----------NSSSHTTTAK---------------------------------GPGSG----FLHPAAATNANSLN----------STFSVLPQR-----FPQFQQHRAVYNSFSFPGQAARYP-----------------WMAFPRNSIM--------------HLNHTANP---------------------------------------------------------------TSNSNFLDLN--LPPQHNTGLGGIP--VAGEE----------------------EVKVST----------------------MPLSTSS---------------------------------------------------------------HSLQQGQQP---------------TSLHTTVA----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BT14-1", "uniprot_id": "CNOT4_MOUSE", "id": "Q8BT14-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYK-LNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNHSAR--------------------------SPFEGAVTESQS-----LFSDNFRHPNPIPSGLPPFPSSPQTPSDWP----------------TAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVT--RKALADLIEKELSVQDQPSLSPTSLQ-----------NASSHTTTAK---------------------------------GPGSG----FLHSAAPTNANSLN----------STFSVLPQR-----FPQFQQHRAVYNSFGFPGQAARYP-----------------WMAFPRNSIM--------------HLNHTANP---------------------------------------------------------------TSNSNFLDLN--LPPQHNTGLGGIP--IAGEE----------------------EVKVST----------------------MPLSASS---------------------------------------------------------------HSLQQGQQP---------------TSLHTTVA----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNF0-1", "uniprot_id": "A0ABZ3NNF0_RAT", "id": "A0ABZ3NNF0-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYK-LNPNFLQLSTGSVDKNKNKVTPLQRYDVPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNHSAR--------------------------SPFEGAVTESQS-----LFSDNFRHPNPIPSGLPPFPSSPQTPSDWP----------------TAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVT--RKALADLIEKELSVQDQPSLSSTSLQ-----------NSSSHTTSAK---------------------------------GPGSG----FLHPAAPANANSLN----------STFSVLPQR-----FPQFQQHRAVYNSFGFPGQAARYP-----------------WMAFPRNSIM--------------HLNHTANP---------------------------------------------------------------TSNSNFLDLN--LPPQHNTGLGGIP--IADNNSSVESLNMKEWQDGLRALLPNININFGG----------------------LPNSSSPSNANHSAPTSNTATTDSVSWDSPGSWTDPAIITGIPASSGNT--------------------LDSIQDDNPP---------------HWLKSLQALT-----EVDGPSAASPQPHHSAPFSTQIPLHRASWNPYPPPSNPSSFHSPPPGFQTA--------------FRPPSKTPTDLLQSSTLDRH--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PB92-1", "uniprot_id": "M9PB92_DROME", "id": "M9PB92-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "--------------------MNGLSSNDDAVECPLCMEPLEVDDLTFFPCTCGYQICRFCWHRIRTDE--NKLCPACRKEYPENPADFKPLSQE-------EMIAFKSQKRQRDQQRKQKITENRKHLANVRVVQKNLVFVVGLPPRLADADILKKHE---YFGKYGKIHKVVINPSTTYAGVQV-----RVGPSASAYVTYVNNSDALRAIQSVNNIMIDGRLIKTSLGTTKYCSHFMKNQQCPKGDCMYLHELGDPEASFTKEEMHQGKHLEYEKRLHDTLIASLGPNATGIVNGNGASKANVAIPSSSSASSSSSGSGTNGSSASGNAQQKEAWPSLSVSPINGKEAAATATSSSGKSKREKLRNEKRHEKNKAKNKNGSNTNANASNKENYVPETRSSTSTETFAEATADAPASTKAEPPQASSNRTRADRGKDRTTASAKEQKKSKEAAPAPAASKPAERVETSESTIRQKKAEVTES--CEDNLPQKRLAGTNVQRSVSSCSENSEGHVSESSLSEKSLTGDYVEEKCNSVNSESQQESVKFQEELEKSNEAIVEAETILPTAESSEDISPAAVAPGNGEVEGCLPVVDPVEPPSLADNGSRVTDALSKLNIFDDTPSFFTSPSFQQAPILKNKLDLEMRQSHLPDLVNDIDGIQKASNTNEWEEAFKNVMMGNTQHMEEQLLQQQHLQQHQNLRHQLVLQQEEFLRMQELQKRNNFATQINGPANDFLRAYELRAQANAIIQQQLLQQHAGENLFGGNMSKFFDFHKSQPQSHHQYLNGHPPQINGNGAVPEPQRVAASLESNRLNSPFVENGLINSQQQQQQQQQQQKQRMMGMYEFMPPNTQSQQNRFTQNSIVDDDLGFDPFVETQKGLAELMENEVVQKQSINNENPLPKLPPQPQVPPHPQLVDNLQRARMPPPGFNHVNTLGLGGASRLQLTSKIIPFMNMPVNGVGNSGAQGQHQMPMGVNWNAPMGMHQNPGQPVGDSQLQHPMAHNKVYNNSDWTSMDPAILSFRQYSSFPQNQIPPHPQQQQDLFLQHLAQQQNSQSGGFNNQAQQMLPMGMPNSLLNGQQTQPPQVNANVQGMLEFLKSRQFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34909-1", "uniprot_id": "NOT4_YEAST", "id": "P34909-1", "name": "General negative regulator of transcription subunit 4", "aln": "MMNPHVQENLQAIHNALSNFDTSFLSEDEEDYCPLCIEPMDITDKNFFPCPCGYQICQFCYNNIRQNPELNGRCPACRRKYDDENVRYVTLSPEELKMERAKLARKEKERKHREKERKENEYTNRKHLSGTRVIQKNLVYVVGINPPVPYEEVAPTLKSEKYFGQYGKINKIVVNRKTPHSNNTTSEHYHHHSPGYGVYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTKYCSSYLRGLPCPNPNCMFLHEPGEEADSFNKRELHNKQQAQQQSGGTAFTRSGIHNNISTSTAGSNTNLLSENFTGTPSPAAMRAQLHHDSHTNAG-TPVLTPAPVPAGSNPWGVTQSATPVTSINLSKN--------------------------SSSINLPTLNDS-----LGHHTTPTTENTITSTTTTTNTNATSHSHG------------------SKKKQSLAAEEYKDPYDALGNAVDFLDARLHSLSNYQKRPISIK------SNIIDEETYKKYPSLFSWDKIEA----------SKKSDNTLAN------------------------------------------KLVEILAIKPIDYT---------ASVVQFLQSVN-----VGVNDNITITDNTKTPTQPIRLQ-------------------TVSQQIQP--------------PLNVSTPP------------------------------------------------------------------PGIFGPQHKVPIQQQQ-MGDTS----------------------------------------------------------SRNS-----------------------------------------------------------------SDLLNQLIN---------------GRKIIAGN----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::: ****:**::: * .****.******:**::.** : * *****: * :: . : .** * :: :.::::::::**:: *****:..**:*****:***: :. :: : ***::***:*:*:* .*.::. .*. ..*:*: ..** *.* *:. :*** :*:: ******* :::. **: :**:*** *: **.*.*:: :: : :. : * *. . . . . . .. : : . . .. . :* . * . * . . . * . . .. .. ..: * . . .:* . .: : . .: : . :. ::. . :* .: . .*. .: * . :. . * ...: . .:: : :. : : :: *: . ::. : * .:: :.. . . .: .: ", "identical_positions": 103, "similar_positions": 184, "identity": "9.36%" }, { "cls_id": "homologset.agr.SGD:S000000871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A904-1", "uniprot_id": "D4A904_RAT", "id": "D4A904-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "MTCHTPNAPRSHSGPPIPPRPESDPAQLNGKLRTPSVVRSRPTVTCGWGRPVGLVVVMATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGARSASPGRRLSTARAH----VEDNEGTKGRVQSPAVEEPPWTP---LPTPLESPAPPAGKSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVVEVDEEVFGCPQAVSRLAFALAFLQRMDMKPLVVLGLPAPTAPSG-----------------CLSFWEAKAQLAQSCKVLVNELRHNAATAVPFFGGGSVLSAAEPAPHASYGG-IVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRDTSQ-KILSNVNLPADLDLVTNAEWLSTKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRSLDSLD-----QGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4H7-1", "uniprot_id": "NAGS_MOUSE", "id": "Q8R4H7-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGAKSASPGRRLSTARAH----AEDAEGAKGRVQSPAVEEPSWTP---LPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVMEVDEEVIRCPQAVSRLAFALAFLQRMDMKPLVVLGLPTPTAPSG-----------------CLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGG-IVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRNNSQ-KILSNVNLPADLDLVTNAEWLSIKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRNLDSLD-----QGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N159-1", "uniprot_id": "NAGS_HUMAN", "id": "Q8N159-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MATALMAVVLRAAAVAPRLRGRGGTGGARRLSCGARRRAARGTSPGRRLSTAWSQPQPPPEEYAGADDVSQSPVAEEPSWVPSPRPPVPHESPEPPSGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCHHSADKPFAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSG-----------------CLSFWEAKAQLAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGG-IVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLRDSSH-KVLSNVNLPADLDLVCNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGTLFKNAERMLRVRSLDKLD-----QGRLVDLVNASFGKKLRDDYLASLRPRLHSIYVSEGYNAAAILTMEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFHKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCP8-1", "uniprot_id": "NAGS_DANRE", "id": "E7FCP8-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MAKVNSGSSGCRAMVMAGQFWTKPFALSSQRSGPHRRSAAEVN---RRMSSSRTAG-------HGSKTPLWS---QQESYNH-----SSLGERSAWSNRTLIYRDVKAFLREIGGDPREARYWLTHFQRAGSTP--AFAVLEVDPSVFDSHEMVQSLAFGLSFLQRMDMKLVVVMGLPAEITEDDHTR-------------SATDSPLARTVMVKHCQALTEALQDNSANVMPFFSSEALLQLQDNPLDGSSSGPSVVVDSALLQWTLDCRVIPLVCPVGRDTTGRSSVLRSIQVTTAISQTLQPLKVIFLNSSGGIRNQNH-KVLGLVSLPGDLPALSCAEWLNEVEQKRIGSIAELLNLLPVESSAVLTSANTLLTELFSHKGSGTLFKNGDPIRRYSSLEDID-----VDRLLALINKSFEKNLREDYIASLEGRLHSVYLSEGYSAAAIITTEPVNSGTPYLDKFVVSSSKQGQGTGQILWECIRQDFSKLFWRSRTTNRINPWYFKHCDGSFVNGHWIVFWLGLSDIRESYELVEFAKSHPDSFCSLSTTETKPLQQHHGS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01217-1", "uniprot_id": "ARG56_YEAST", "id": "Q01217-1", "name": "Protein ARG5,6, mitochondrial", "aln": "---------------------------------------------------------MPSASLLVSTKRLNASKFQKFVSSLNKSTIAGFASVPLRAPPSVAFTRKKVGYSKR-----------------------------------YVSSTNGFSATRSTVIQLLNNIS-TKREVEQYLKYFTSVSQQQ---FAVIKVGGAIIS--DNLHELASCLAFLYHVGLYPIVLHGTGPQVNGRLEAQGIEPDYIDGIRITDEHTMAVVRKCFLEQNLKLVTALEQLGVRARPITSGVFTADYLDKDKYKLVGN-IKSVTKEPIEASIKAGALPILTSLAETASGQMLNVNADVAAGELARVFEPLKIVYLNEKGGIINGSTGEKISMINLDEEYDDLMKQSWVKYGTKLKIREIKELLDYLPRSSSVAIINVQDLQKELFTDSGAGTMIRRGYKLVKRSSIGEFPSADALRKALQRDAGISSGKESVASYLRYLENSDFVSYADEPLEAVAIVKKD---TNVPTLDKFVCSDAAWLNNVTDNVFNVLRRDFPALQWVVSENDANIAWHFDKSQGSYLKGGKVLFWYGIDDINTISELVENFVKSCDTASTLNSSASSGVFANKKSARSYSTRSTPRPEGVNTNPGRVALIGARGYTGKNLVSLINGHPYLEVAHVSSRELKGQKLQDYTKSEIIYESLQIQDIRKLEEQNAVDFWVMALPNKVCEPFVETIQSVHGKSKIIDLSADHRFVSESDWAYGLPELNDRAKIANAAKIANPGCYATGSQLTISPLTKYINGLPTVFGVSGYSGAGTKPSPKNDPKFLNNNLIPYALSDHIHEREISARIGHNVAFMPHVGQWFQGISLTVSIPIKKGSLSIDEIRKLYRNFYEDEKLVHVIDDIPLVKDIEGTHGVVIGGFKLNDAEDRVVVCATIDNLLKGAATQCLQNINLAMGYGEYAGIPENKIIGV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *... . : . * * . . : . . : : :*.: . *.. :*. * ***::*. :: : : ** *:** ::.: :*: * . .: : : *. *.. .. . *: .. : .. * . :: :.. :*:: .:.. :: : : : .: :::.:.* *:::**..**: : . : :. :.* : : .*:. : :: * ::*. ** **..: .. * .***:..*.**:::.. : : .: .: * . * *: .*: *. . * .* .*.**:. : ..* ***** *.: :. : ::: :*:*: * * .: .*:*.:.:**: : :.** *: **. ***: *: . : * ", "identical_positions": 79, "similar_positions": 166, "identity": "8.19%" }, { "cls_id": "homologset.agr.SGD:S000000872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Q5-1", "uniprot_id": "Q5U2Q5_RAT", "id": "Q5U2Q5-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLEIVMAHKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP-----EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPEDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK---------------------------------------------------------------------------------------LKDKEKAL--KEEEEKER---NTAAMVCSLENREECLMCGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07742-1", "uniprot_id": "RIR1_MOUSE", "id": "P07742-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP-----EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK---------------------------------------------------------------------------------------LKDKEKAL--KEEEEKER---NTAAMVCSLENREECLMCGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23921-1", "uniprot_id": "RIR1_HUMAN", "id": "P23921-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTS-----EHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK---------------------------------------------------------------------------------------LKDKEKVS--KEEEEKER---NTAAMVCSLENRDECLMCGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79732-1", "uniprot_id": "RIR1_DANRE", "id": "P79732-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGGQEGVMFDKITSRIQKLCYGLNSDFVDPTQITMKVIQGLYSGVTTVELDTLAAETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKETLDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMYLEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLDECWGEEFEKLYAKYEQEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNLGTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYVTS-----ERTFDFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFESTEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDWAALKEKIANDGVRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAYIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLNKEK---------------------------------------------------------------------------------------LKETQKTTSSEDEETKER---NKAAMVCSLENRHECLMCGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48591-1", "uniprot_id": "RIR1_DROME", "id": "P48591-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTP-----EKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSMN--------------------------------------------------------------------------------GQNGTAEGSPQKYEEDRER---KMADMVCSLENKDACMSCGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21524-1", "uniprot_id": "RIR1_YEAST", "id": "P21524-1", "name": "Ribonucleoside-diphosphate reductase large chain 1", "aln": "-----------MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRG-KTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYMPSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVEVPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* **** :* * *****:**.:***.*: ..:*.. :* ::*.*:* **** ***.**** .* * ***** ******:*****:*.* **.*.****.::* ..: *:::. ::* : :***:*:***** *.:************: **::******::***::*** .** **:*****:* ::********* *.* :**:*****::*. ******:.::::**:***:*****: : **:.* *.****.****:**:** **.********.*******:****** *:*:*::::** **** ****** ************* * *:*:.* ..*** : :*:*** ** **::** :.:***.**::*:*:*.***.*::::**:******::*:*.**.**** *****:: ** *******:** :: . *::*:** .::*::.:***::** ****: ** ** ****:.:*:**:**:::*:* *::* ** *** *******:.::*:**:** ***:*: *.*.*:****:***: * .:*** *::.* *:**** :********:**:* **.:** *:*:* *********:** :**:**.: .:*.: **: :*: .**** : :* .:::********* *: ::***:*..:****:*:*:.: *. *****:***.** ***********:..: .****:::: : : :* * : :.*:::* . * *..", "identical_positions": 440, "similar_positions": 227, "identity": "48.89%" }, { "cls_id": "homologset.agr.SGD:S000000873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63172-1", "uniprot_id": "DYLT1_HUMAN", "id": "P63172-1", "name": "Dynein light chain Tctex-type 1", "aln": "----MEDYQ-AAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKNGAG-------LHTASSCFWDSSTDGSCTVRWENKTMY--CIVSAFGLSI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z336-1", "uniprot_id": "DYLT1_RAT", "id": "Q9Z336-1", "name": "Dynein light chain Tctex-type 1", "aln": "----MEDFQ-ASEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKNGAG-------LHTASSCFWDSSTDGSCTVRWENKTMY--CIVSAFGLSI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51807-1", "uniprot_id": "DYLT1_MOUSE", "id": "P51807-1", "name": "Dynein light chain Tctex-type 1", "aln": "----MEDFQ-ASEETAFVVDEVSSIVKEAIESAIGGNAYQHSKVNQWTTNVLEQTLSQLTKLGRPFKYIVTCVIMQKNGAG-------LHSASSCFWDSSTDGSCTVRWENKTMY--CIVSTFGLSI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q94524-1", "uniprot_id": "DYLT_DROME", "id": "Q94524-1", "name": "Dynein light chain Tctex-type", "aln": "----MDD---SREESQFIVDDVSKTIKEAIETTIGGNAYQHDKVNNWTGQVVENCLTVLTKEQKPYKYIVTAMIMQKNGAG-------LHTASSCYWNNDTDGSCTVRWENKTMY--CIVSVFGLAV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P56387-1", "uniprot_id": "DYLT3_MOUSE", "id": "P56387-1", "name": "Dynein light chain Tctex-type 3", "aln": "----MEGYQRPCDEVGFNADEAHNIVKECVDGVLGGNDYNENNINQWTASIVEQSITHLVKLGKAYKYIVTCAVVQRSPYG-------FHTASSCFWDTTSDGTCTIRWENRTMN--CIVNVFAVAIVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FAB7-1", "uniprot_id": "F7FAB7_RAT", "id": "F7FAB7-1", "name": "Dynein light chain Tctex-type 3", "aln": "----MDGYQRPCDEIGFNAEEAHNIVKECVEGVLGGNDYNQNSINQWTASIVEQSIAHLVKLGKAYKYIVTCAVVQRSPYG-------FHVASSCFWDTTSDGTCTVRWENRTMN--CVVNVFAVAIVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51808-1", "uniprot_id": "DYLT3_HUMAN", "id": "P51808-1", "name": "Dynein light chain Tctex-type 3", "aln": "----MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGKAYKYIVTCAVVQKSAYG-------FHTASSCFWDTTSDGTCTVRWENRTMN--CIVNVFAIAIVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40045-1", "uniprot_id": "TDA2_YEAST", "id": "P40045-1", "name": "Topoisomerase I damage affected protein 2", "aln": "MSMQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLS-TESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNNNECYLITILWLHK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: : . . ::*. : ..: : . :. : ::: : * * :***.: :: . . :: .. *:. .** . : *::. ::. : : ", "identical_positions": 10, "similar_positions": 47, "identity": "7.75%" }, { "cls_id": "homologset.agr.SGD:S000000875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZS1-1", "uniprot_id": "AL1B1_MOUSE", "id": "Q9CZS1-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTARLLLPRLLCLQGRTTSYSTA-----AALPNPIPNPE-------------------ICYNKLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWHGKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCHEALFFNMGQCCCAGSRTFVEESIYREFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERILGYIRLGQKEGAKLLCGGER-LGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFKK--IEEVIQRANNTRYGLAAAVFTRDLDKAIYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLRAYTEVKTVTIKVPEKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLNARFLVPRLLCLQGRTTSYSTA-----AALPNPIPNPE-------------------IRYNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKWHGKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKKRKVGNPFELDTQQGPQVDKEQFEKILGYIRLGQKEGAKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKK--IEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ML--RFLAPRLLSLQGRTARYSSA-----AALPSPILNPD-------------------IPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQ----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKK--IEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ML--RAAARFGPRLGRRLLSAAAT-----QAVPAPNQQPE-------------------VFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKT--IEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLR-VLKTGALLRSQAKNFAAAVANY---SSLPQPQTTPD-------------------ILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDGD----FFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKK--LDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q62148-1", "uniprot_id": "AL1A2_MOUSE", "id": "Q62148-1", "name": "Retinal dehydrogenase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPAALMASLQLLPSPTPNLE-------------------IKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63639-1", "uniprot_id": "AL1A2_RAT", "id": "Q63639-1", "name": "Retinal dehydrogenase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPAALMASLQLLPSPTPNLE-------------------IKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94788-1", "uniprot_id": "AL1A2_HUMAN", "id": "O94788-1", "name": "Retinal dehydrogenase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLE-------------------IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATANGAVENGQPDRKPPA-------LPRPIRNLE-------------------VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDN----VVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKS--IEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24549-1", "uniprot_id": "AL1A1_MOUSE", "id": "P24549-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPAQPA------------VPAPLADLK-------------------IQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGD----IFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--VDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPAQPA------------VPAPLANLK-------------------IQHTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIHGQTIPSDGD----IFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYVLGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--IDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35945-1", "uniprot_id": "AL1A7_MOUSE", "id": "O35945-1", "name": "Aldehyde dehydrogenase, cytosolic 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPAQPA------------VPAPLANLK-------------------IQHTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMESMNAGKVFAHAYLLDVEISIKALQYFAGWADKIHGQTIPSDGN----IFTYTRREPIGVCGQIIPWNGPLIIFTWKLGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGGAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFVRRSVERAKKYILGNPLNSGINQGPQIDKEQHNKILGLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--MDDVIKRANNTTYGLAAGVFTKDLDKAITVSSALQAGMVWVNCYLAVPVQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMQISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSGTPD------------LPVLLTDLK-------------------IQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGN----FFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGP-WGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--LDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6I6-1", "uniprot_id": "A0A0B4K6I6_DROME", "id": "A0A0B4K6I6-1", "name": "Aldehyde dehydrogenase domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMNKLQKLLAHQLAVSRKWS----KFDHTYAQCE-------------------PNYCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAGG-----FVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKR-IGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSS--LEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKLL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGETSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGE-WGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQ-VQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75891-1", "uniprot_id": "AL1L1_HUMAN", "id": "O75891-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGR-WGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQ-VPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40047-1", "uniprot_id": "ALDH5_YEAST", "id": "P40047-1", "name": "Aldehyde dehydrogenase 5, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSRTRAAAPNSRIFTRSLLRLYSQAPLRVPITLPNG---------------FTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAF--ETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGK-SLFCARGDVALVSKYLRSCGGWADKIYGNVIDTGKN----HFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADT-VKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGAR-HGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFST--VDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIAIDKPIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **..:: : : . **: . : : . *:* ** **: ** * :.. * . : .*. *::..: **::*: : * . .: : .** ** * .* . . : :**:** . * *** *::: ** ...*. * .:::* *: *.*:** . * :**:* **:*:: * * .* :: * : *:.****. *: : .. : :*:*:******.* :: * ::: ** .:* : *: * *..* ::.: :: *.: : . :*.*: :*.* . ::: . :** * ** * *.:**** * : * :.:** ***: : :* :: :: ** :** :.: *.::::* . : :* *::* * **** ** *:: *: .: * . *:: . ", "identical_positions": 123, "similar_positions": 148, "identity": "13.21%" }, { "cls_id": "homologset.agr.SGD:S000000876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62847-1", "uniprot_id": "RS24_HUMAN", "id": "P62847-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62849-1", "uniprot_id": "RS24_MOUSE", "id": "P62849-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62850-1", "uniprot_id": "RS24_RAT", "id": "P62850-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W229-1", "uniprot_id": "Q9W229_DROME", "id": "Q9W229-1", "name": "40S ribosomal protein S24", "aln": "MSGTTATIRTRKFMTNRLLARKQMVCDVLHPGLSSVNKTEIREKLAAMYKVTPDVVFAFGFRTNFGGGRSTGFALIYDTLDFAKKFEPKYRLARHGLFEQ-KKQTRKQRKERRNRMKKVRGTAK--AKIGTGKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX31-1", "uniprot_id": "RS24A_YEAST", "id": "P0CX31-1", "name": "Small ribosomal subunit protein eS24A", "aln": "MS-DAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :.******.::* ** ***:* *****. :.* * *:***** :**. *.: .*****:****::.**.::*::: *** **.:**.*:** *: :* :*:***:::** **: **.* *: : :: ", "identical_positions": 66, "similar_positions": 43, "identity": "48.18%" }, { "cls_id": "homologset.agr.SGD:S000000877", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35822-1", "uniprot_id": "PTPRK_MOUSE", "id": "P35822-1", "name": "Receptor-type tyrosine-protein phosphatase kappa", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MD-VAAAALPAFVALWLLYPWPLLGSALGQFSAGGCTFDD---GPGACDYHQDLYDD-FEWVHVSAQEPHYLPPEMPQGSYMVVDSSNHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLN------PGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQ----------------VIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAG-----QNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAV-----------NAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRG-----HNESRADCLDMDPKAP-----------------------------------------------------------------------------------------QHVVNHLPPYTNVSLKMILTNPEGR-------------------------------------------------------------------------------------------------------KESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPL--EPNGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWN--------------------------STHHVFMHLHPGTTYQFFIRASTVK-----------------------------GFGPATAINVTTNISAPSLPDYEGVDASL---------------------NETATTITVLLRPAQAK------------------------------------------------------------------------------------------------------GAPISAYQIVVEQLHPHRTKREAGAMECYQVPVT--------------------------------------------------------------------------------------------------YQNALSGGAPYYFAAELPPGNLPEPAPFTVGDNRT--------------------------------------------------------------------------------------------------------------------------------------------YKGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLV-------------------------VIVIVKKS------------KLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAED--------------------------------------------------------------------------------------------------------------------------------------PLSLTFMDQHNFSPRLPNDPLVPTAVLDENHSATAESS--------------------------------------------------------RLLDVPRYLCEGTESPYQTGQ------------------LHPAIRVADLLQHINLMKTSDSYG-----FKEEYESFFEG---QSASWDVAKKDQNRAKNRYGNIIAY------------------------------------DHSRVILQPVE---DDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMVWQEQSACIVMVTNLVEVGR--------------------VKCYKYWPD---DTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNE-----------IREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPS--AGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDS--QTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG--------------------ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQ---GCPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIFRICNLT---RPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGR-------TIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15262-1", "uniprot_id": "PTPRK_HUMAN", "id": "Q15262-1", "name": "Receptor-type tyrosine-protein phosphatase kappa", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDD---GPGACDYHQDLYDD-FEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLN------PGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQ----------------VIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAG-----QNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAV-----------NAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRG-----HNESKADCLDMDPKAP-----------------------------------------------------------------------------------------QHVVNHLPPYTNVSLKMILTNPEGR-------------------------------------------------------------------------------------------------------KESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPL--DPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWN--------------------------STHHVFMHLHPGTTYQFFIRASTVK-----------------------------GFGPATAINVTTNISAPTLPDYEGVDASL---------------------NETATTITVLLRPAQAK------------------------------------------------------------------------------------------------------GAPISAYQIVVEELHPHRTKREAGAMECYQVPVT--------------------------------------------------------------------------------------------------YQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRT--------------------------------------------------------------------------------------------------------------------------------------------YQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLV-------------------------VILIVKKS------------KLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAED--------------------------------------------------------------------------------------------------------------------------------------PLSITFMDQHNFSPRY------------ENHSATAESS--------------------------------------------------------RLLDVPRYLCEGTESPYQTGQ------------------LHPAIRVADLLQHINLMKTSDSYG-----FKEEYESFFEG---QSASWDVAKKDQNRAKNRYGNIIAY------------------------------------DHSRVILQPVE---DDPSSDYINANYID------GYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGR--------------------VKCYKYWPD---DTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNE-----------IREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPS--AGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDS--QTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG--------------------ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQ---GCPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIFRICNLT---RPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGR-------TIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28828-1", "uniprot_id": "PTPRM_MOUSE", "id": "P28828-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MRTLGTCLVTLAG---------LLLTAAGETFSGGCLFDE---PYSTCGYSQADEDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAA------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAISTFWPNFYQ----------------VIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPV-----------DSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVG-----GQEQVREEVSWDTDNSH---------------------------------------------------------------------------------------PQHTITNLSPYTNVSVKLILMNPEGR-------------------------------------------------------------------------------------------------------KESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPT--QTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGN--------------------------ETHFLFFGLYPGTTYSFTIRASTAK-----------------------------GFGPPATNQFTTKISAPSMPAYE-FETPL---------------------NQTDNTVTVMLKPAQSR------------------------------------------------------------------------------------------------------GAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIH--------------------------------------------------------------------------------------------------FQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAVTPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLG-------------------------VVLVMKKR------------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEA--------------------------------------------------------------------------------------------------------------------------------------FSFMGTHNLNGRSVSSPSS--------FTMKTNTLSTSVPNSYYPD-------------------------------------ETHTMASDTSSLAQPHTYKKREAADVPYQTGQ------------------LHPAIRVADLLQHITQMKCAEGYG-----FKEEYESFFEG---QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQMLE---GDNNSDYINGNYID------GYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGR--------------------VKCCKYWPD---DTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHE-----------IREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPN--AGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDP--QTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDG--------------------ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQ---LCPQYWPENGVHR-HGPIQVEFVSADLEEDIISRIFRIYNAS---RPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGR-------TVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8V0-1", "uniprot_id": "A0A0G2K8V0_RAT", "id": "A0A0G2K8V0-1", "name": "protein-tyrosine-phosphatase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MRTLGTCLVTLAG---------LLLTAAGETFSGGCLFEE---PYSTCGYSQADDDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAA------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAVSTFWPNFYQ----------------VIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPV-----------DSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVRYCYQVG-----GQEQVREEVSWDMDNSH---------------------------------------------------------------------------------------PQHTITNLSPYTNVSVKLILMNPEGR-------------------------------------------------------------------------------------------------------KESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPT--QTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGN--------------------------ETHFLFFGLYPGTTYSFTIRASTAK-----------------------------GFGPPATNQFTTKISAPSMPAYE-FETPL---------------------NQTDNTVTVLLKPAQSR------------------------------------------------------------------------------------------------------GAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIH--------------------------------------------------------------------------------------------------FQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATKAAIIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLTTPYIRIAPAAGDGQLTGAVTPKPVPEPEKGTDHTVKIAGVIAGILLFVIIFLG-------------------------VVLVMKKR------------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEA--------------------------------------------------------------------------------------------------------------------------------------FSFMDTHNLNGRSVSSPSS--------FTMKTNTLSTSVPNSYYPDPFVPTA------------------------ILVPINDETHTMASDTSSLAQPHTYKKREAADVPYQTGQ------------------LHPAIRVADLLQHITQMKCAEGYG-----FKEEYESFFEG---QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQMLE---GDNSSDYINGNYID------GYHRPNHYIATQGPMQETVYDFWRMVWYENTASIIMVTNLVEVGR--------------------VKCCKYWPD---DTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHE-----------IREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPN--AGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDP--QTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDG--------------------ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPTQ---LCPQYWPENGVHR-HGPIQVEFVSADLEEDIISRIFRIYNAS---RPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGR-------TVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNAG--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28827-1", "uniprot_id": "PTPRM_HUMAN", "id": "P28827-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MRGLGTCLATLAG---------LLLTAAGETFSGGCLFDE---PYSTCGYSQSEGDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNSP------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQ----------------VIFEVITS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPV-----------DSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG-----GQEQVREEVSWDTENSH---------------------------------------------------------------------------------------PQHTITNLSPYTNVSVKLILMNPEGR-------------------------------------------------------------------------------------------------------KESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPT--QTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGN--------------------------ETHFLFFGLYPGTTYSFTIRASTAK-----------------------------GFGPPATNQFTTKISAPSMPAYE-LETPL---------------------NQTDNTVTVMLKPAHSR------------------------------------------------------------------------------------------------------GAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIH--------------------------------------------------------------------------------------------------FQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAATPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLG-------------------------VVLVMKKR------------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEA--------------------------------------------------------------------------------------------------------------------------------------FSFMDTHNLNGRSVSSPSS--------FTMKTNTLSTSVPNSYYPD-------------------------------------ETHTMASDTSSLVQSHTYKKREPADVPYQTGQ------------------LHPAIRVADLLQHITQMKCAEGYG-----FKEEYESFFEG---QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQTIE---GDTNSDYINGNYID------GYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGR--------------------VKCCKYWPD---DTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHE-----------IREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPS--AGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDP--QTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDG--------------------ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQ---LCPQYWPENGVHR-HGPIQVEFVSADLEEDIISRIFRIYNAA---RPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGR-------TVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99M80-1", "uniprot_id": "PTPRT_MOUSE", "id": "Q99M80-1", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MGSLGGLALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDE---HYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSS------PGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQ----------------VIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVG-----QNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIV-----------DSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-----QQQYEAEEVIQTSS-------------------------------------------------------------------------------------------HYTLRGLRPFMTIRLRLLLSNPEGR-------------------------------------------------------------------------------------------------------MESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPN--ETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRN--------------------------ETHHLFVGLYPGTTYSFTIKASTAK-----------------------------GFGPPVTTRIATKISAPSMPEYD-ADTPL---------------------NETDTTITVMLKPAQSR------------------------------------------------------------------------------------------------------GAPVSVYQLVVKEERLQKSRRAADIIECFSVPVS--------------------------------------------------------------------------------------------------YRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGAPMGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQVTPGTPLCLLT-----TASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLG-------------------------VMLTIKRR------------KLAKKQKETQSGAQREMG-PVASTDKPTAKLGTNRNDE--------------------------------------------------------------------------------------------------------------------------------------GFSSSSQDVNGFTDGSRGE--------LSQPTLTIQT-------------------------------------------------------------HPYRTCDPVEMSYPRDQ------------------FQPAIRVADLLQHITQMKRGQGYG-----FKEEYEALPEG---QTASWDTAKEDENRNKNRYGNIISY------------------------------------DHSRVRLLVLD---GDPHSDYINANYID------GYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGR--------------------VKCVRYWPD---DTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHE-----------IRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPE--AGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDP--QTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG--------------------ESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQ---LCMQYWPEKTSGC-YGPIQVEFVSADIDEDIIHRIFRICNMA---RPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGR-------TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFL3-1", "uniprot_id": "A0A8I6AFL3_RAT", "id": "A0A8I6AFL3-1", "name": "protein-tyrosine-phosphatase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MGSLGALALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDE---HYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSS------PGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQ----------------VIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVG-----QNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIV-----------DSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-----QQQYEAEEVIQTSS-------------------------------------------------------------------------------------------HYTLRGLRPFMTIRLRLLLSNPEGR-------------------------------------------------------------------------------------------------------MESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPN--ETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRN--------------------------ETHHLFVGLYPGTTYSFTIKASTAK-----------------------------GFGPPVTTRIATKISAPSMPEYD-ADSPL---------------------NETDTTITVMLKPAQSR------------------------------------------------------------------------------------------------------GAPVSVYQLVVKEERLQKSRRAADIIECFSVPVS--------------------------------------------------------------------------------------------------YRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLG-------------------------VMLTIKRR------------KLAKKQKETQSGAQREMG-PVASTDKPTTKLSTNRNDE--------------------------------------------------------------------------------------------------------------------------------------GFSSSSQDVNGFTDGSRGE--------LSQPTLTIQT-------------------------------------------------------------HPYRTCDPVEMSYPRDQ------------------FQPAIRVADLLQHITQMKRGQGYG-----FKEEYEALPEG---QTASWDTAKEDENRNKNRYGNIISY------------------------------------DHSRVRLLVLD---GDPHSDYINANYID------GYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGTATLGRAASPGMVKCVRYWPD---DTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHE-----------IRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPE--AGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDP--QTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG--------------------ESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQ---LCMQYWPEKTSGC-YGPIQVEFVSADIDEDIIHRIFRICNMA---RPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKAVRRLEKWQEEYDGREGR-------TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14522-3", "uniprot_id": "PTPRT_HUMAN", "id": "O14522-3", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MASLAALALSLL----LRLQLPPLPGARAQSAAGGCSFDE---HYSNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSS------PGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQ----------------VIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVG-----QNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIV-----------DSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-----QQQYEAEEVIQTSS-------------------------------------------------------------------------------------------HYTLRGLRPFMTIRLRLLLSNPEGR-------------------------------------------------------------------------------------------------------MESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPN--ETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRN--------------------------ETHHLFVGLYPGTTYSFTIKASTAK-----------------------------GFGPPVTTRIATKISAPSMPEYD-TDTPL---------------------NETDTTITVMLKPAQSR------------------------------------------------------------------------------------------------------GAPVSVYQLVVKEERLQKSRRAADIIECFSVPVS--------------------------------------------------------------------------------------------------YRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLG-------------------------VMLTIKRRRNA--YSYSYYLKLAKKQKETQSGAQREMG-PVASADKPTTKLSASRNDE--------------------------------------------------------------------------------------------------------------------------------------GFSSSSQDVNGFTDGSRGE--------LSQPTLTIQT-------------------------------------------------------------HPYRTCDPVEMSYPRDQ------------------FQPAIRVADLLQHITQMKRGQGYG-----FKEEYEALPEG---QTASWDTAKEDENRNKNRYGNIISY------------------------------------DHSRVRLLVLD---GDPHSDYINANYID------GYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGR--------------------VKCVRYWPD---DTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHE-----------IRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPE--AGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDP--QTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG--------------------ESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQ---FCMQYWPEKTSGC-YGPIQVEFVSADIDEDIIHRIFRICNMA---RPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGR-------TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AUH1-1", "uniprot_id": "PTPRU_MOUSE", "id": "B1AUH1-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MARAQALVLALTF---------QFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDD-FQWEQVRIHPGTRTPEDLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLYSRDGHS------PGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQ----------------VLFEALISPDHKGYIGLDDILLFSYPCAKAPHFSRLGDVEVNAG-----QNASFQCMAAGRAAEAEHFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAV-----------NLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLG---GSHNQTIRECVKMERGAS-----------------------------------------------------------------------------------------RYTIKNLLPFRNIHVRLILTNPEGR-------------------------------------------------------------------------------------------------------KEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQ--EPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRN--------------------------ETYHVFSNLHPGTTYLFSVRARTSK-----------------------------GFGQAALTEITTNISAPSF-DYADMPSPL---------------------GESENTITVLLRPAQGR------------------------------------------------------------------------------------------------------GAPISVYQVVVEEERPRRLRREPGAQDCFSVPLT--------------------------------------------------------------------------------------------------FETALARGLVHYFGAELAASSLLEAMPFTVGDNQT--------------------------------------------------------------------------------------------------------------------------------------------YRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLG-------------------------AIIVIIRKGRDRYAYSYYP-KPVNMTKATVN-YRQEKTHMMSAVDRSFTDQSTLQEDE--------------------------------------------------------------------------------------------------------------------------------------RLGLSFMDAPGYSPRGDQRSGG-----VTEASSLLGGS-------------------------------------------------------------PRRPCGRKGSPYHTGQ------------------LHPAVRVADLLQHINQMKTAEGYG-----FKQEYESFFEG-------WDATKKKDKLKGGRQEPVSAY------------------------------------DRHHVKLHPML---ADPDADYISANYID------GYHRSNHFIATQGPKPEMIYDFWRMVWQEQCASIVMITKLVEVGR--------------------VKCSRYWPE---DSDMYGDIKITLVKTETLAEYVVRTFALERRGYSA-----------RHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPD--AGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDP--QSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDG--------------------DPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ-YGLMEVEFVSGTANEDLVSRVFRVQNSS---RLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAES--GDGR-------TVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAG7-1", "uniprot_id": "F1MAG7_RAT", "id": "F1MAG7-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MARAQALVLALTF---------QFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDD-FQWEQVRIHPGTRTPADLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLFSRDGHS------PGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQ----------------VLFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAG-----QNASFQCMAAGRAAEAERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAV-----------NLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYHYTLG---GSHNQTIRECVKMERGAS-----------------------------------------------------------------------------------------RYTIKNLLPFRNVHVRLILTNPEGR-------------------------------------------------------------------------------------------------------KEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQ--EPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRN--------------------------ETYHVFSNLQPGTTYLFSVRARTSK-----------------------------GFGQAALTEITTNISAPSF-DYADMPSPL---------------------GESENTITVLLRPAQGR------------------------------------------------------------------------------------------------------GAPISVYQVVVEEERPRRLRREPGGQDCFSVPLT--------------------------------------------------------------------------------------------------FETALARGLVHYFGAELAASSLLEAMPFTVGDNQT--------------------------------------------------------------------------------------------------------------------------------------------YRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLG-------------------------AIIIIIRKGRDRYAYSYYP-KPVNMAKATVN-YRQEKTHMMTAVDRSFTDQSTLQEDE--------------------------------------------------------------------------------------------------------------------------------------RLGLSFMDAPGYSPRGDQRSSG-----VTEASSLLGGS-------------------------------------------------------------PRRPCGRKGSPYHTGQ------------------LHPAVRVADLLQHINQMKTAEGYG-----FKQEYESFFEG-------WDATKKKDKLKSGRQEPVSAY------------------------------------DRHRVKLHPML---GDPDADYISANYIDIRINRQGYHRSNHFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEVGR--------------------VKCSRYWPE---DSDMYGDIKITLVKTETLAEYVVRTFALERRGYSA-----------RHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPD--AGPVVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDP--QSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDG--------------------DPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ-YGLMEVEFVSGTANEDLVSRVFRVQNSS---RLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAES--GDGR-------TVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92729-1", "uniprot_id": "PTPRU_HUMAN", "id": "Q92729-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MARAQALVLALTF---------QLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDD-FQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHS------PGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQ----------------VLFEALISPDRRGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAG-----QNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAV-----------SLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLG---SSHNQTIRECVKTEQGVS-----------------------------------------------------------------------------------------RYTIKNLLPYRNVHVRLVLTNPEGR-------------------------------------------------------------------------------------------------------KEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQ--EPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRN--------------------------ETYHVFSNLHPGTTYLFSVRARTGK-----------------------------GFGQAALTEITTNISAPSF-DYADMPSPL---------------------GESENTITVLLRPAQGR------------------------------------------------------------------------------------------------------GAPISVYQVIVEEERARRLRREPGGQDCFPVPLT--------------------------------------------------------------------------------------------------FEAALARGLVHYFGAELAASSLPEAMPFTVGDNQT--------------------------------------------------------------------------------------------------------------------------------------------YRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLG-------------------------AIIVIIRKGRDHYAYSYYP-KPVNMTKATVN-YRQEKTHMMSAVDRSFTDQSTLQEDE--------------------------------------------------------------------------------------------------------------------------------------RLGLSFMDTHGYSTRGDQRSGG-----VTEASSLLGGS-------------------------------------------------------------PRRPCGRKGSPYHTGQ------------------LHPAVRVADLLQHINQMKTAEGYG-----FKQEYESFFEG-------WDATKKKDKVKGSRQEPMPAY------------------------------------DRHRVKLHPML---GDPNADYINANYID------GYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGR--------------------VKCSRYWPE---DSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSA-----------RHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPD--AGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDP--QSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDG--------------------DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ-YGLMEVEFMSGTADEDLVARVFRVQNIS---RLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAES--GDGR-------TIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DK56-1", "uniprot_id": "PTPRU_DANRE", "id": "B3DK56-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MNTCAFLLILAV---------QIHADSVEGPTAGCTFDEDSDPSL-CEFSQGEEDD-FDWQLFRAHASPHSTSDLLRGSYMMVNSSQHAAGQRAQLLLQTLSENDTHCVQFSYFLYSRDGHS------PGALRVYVRVNGGPLGIPVWNVSGSRGRQWHQVELAVSTFWPNEYQ----------------ILLEATVD--RKGYIAVDDILLLNYPCYKAPHFSRLGDVEVNAG-----QNATFQCVAAGRPSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQKPEQDLYRCVTQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQLNTNSILGDGPIIRREIEYRASLAPWSEILGV-----------NMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGHNTTVRECLAVEHNTS-----------------------------------------------------------------------------------------RFTLRDLPPFHTIQIRLALANTEGK-------------------------------------------------------------------------------------------------------KEGKEVMFQTEEDIPGGIAPESLTFTPLEDMIFLKWEEPV--EPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKN--------------------------ETYHMFSNLHPGTTYLISVRARTAK-----------------------------GFGQTALTEITTNISAPTF-DYGDMPSPL---------------------SETENTITVLLRPAQGR------------------------------------------------------------------------------------------------------GAPVSTYQVVVEEEAGRKVKRELGIQDCFPIPTS--------------------------------------------------------------------------------------------------HGEAQARGAPHYYTAELPPSSLSEATPFTVGDNHT--------------------------------------------------------------------------------------------------------------------------------------------YNGYWNSPLDPRKNYLVYFQAMSNFRGETRINCIRIARKA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLG-------------------------AIIIIIKKGRDYYSYSYYPRKPGNMNKTPIT-YRQEKSNMMGSMERSFTDQSTLQEDE--------------------------------------------------------------------------------------------------------------------------------------RMALSFMDTHTCSTRSDPRSS------MNESSSLLGGS-------------------------------------------------------------PRRQCGRKGSPYHTGQ------------------LHPAVRVADLLQHINQMKTAEGYG-----FKQEYESFFDG-------WDINKKKDKTKG-RHDTLMGY------------------------------------DRHRVKLHPLL---GDPNSDYINANYID------GYHRSNHFIATQGPKQETVYDFWRMVWQENCFSIVMITKLVEVGR--------------------VKCCKYWPD---ESEMYGDIKITLLKTETLAEYTVRTFALERRGYSA-----------KHEVCQFHFTSWPEHGVPYHATGLLAFIRRVKTSTPLD--AGPVVVHCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCGETAIPVNEFALAYKEMLRVDS--QSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVLPPDRALAFLVTTEG--------------------ESNNYINAALMDSFHRPAAFIVTPHPLPGTTSDFWRLVFDYGCTSVVMLNQLNQSNSAWPCVQYWPEPGLQQ-YGPMQVEFLSMSADEDIITRLFRVKNVT---RLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQREC--GEGR-------TVVHCLNGGGRSGTYCASNILMEMIQYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYLDCLEVR-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q64487-4", "uniprot_id": "PTPRD_MOUSE", "id": "Q64487-4", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------M--VPVARPLSLLLTFFLC-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNP-EPVSYYIIQHKPKNSEEPYKEIDGI-----------ATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIASYELVYRDGD-QGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEF--------------------DDTTEHDMIISGLQPETSYSLTVTAYTTK-----------------------------GDGARSKPKLVSTTGAVPGKPRLVINHTQ---------------------MNTALIQWHPPVDTFGP--LQGYRLKFGRKD----------------------------------------------------------------------------------------MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSAR--------------------------------------------------------------------------------------------------NKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTST-SVQLSWQPPVLA--------------------------------------------------------------------------------------------ERNGVITKYTLLYRDINVPLLPMEHLIVPA-----DTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDG------------------KMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPDVPANENIKGYYIIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAE-------SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIA----ILLYKR--------------------KRAESES-RKSSLPNSKEVPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLK-----FSQEYESIDPG---QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIE---GIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEER--SRV------------------KCDQYWPSR--GTETHGLVQVTLLDTVELATYCVRTFALYKNGSSE-----------KREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPD--AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIET--GENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGV-------------------EGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LD14-1", "uniprot_id": "A0ABK0LD14_RAT", "id": "A0ABK0LD14-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "------------------------------------------------------------------------------------------------------------------------------MPLTSCRM--VPVARLLLLLLAFFLY-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS---GGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRG-RNVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGTPVVTESTATSITLTWDSGNP-EPVSYYIIQHKPKNSEEPYKEIDGI-----------ATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIASYELVYRDGD-QGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDYRPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEF--------------------DDATEHDMIISGLQPETSYSLTVTAYTTK-----------------------------GDGARSKPKLVSTTGAVPGRPRLVINHTQ---------------------MNTALIQWHPPVDTFGP--LQGYRLKFGRKD----------------------------------------------------------------------------------------MEPLTTLEFSEKEDHFTATDIHKGASYIFRLSAR--------------------------------------------------------------------------------------------------NKVGFGEEMVKEISVPEEVPTGFPQNLHSEGTTST-SVQISWQPPVLA--------------------------------------------------------------------------------------------ERNGVITKYTLLYRDINVPLLPMEHLIVPA-----DTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDG------------------KMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPDVPANENIKGYYIIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAE-------SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIA----ILLYKR--------------------KRAESES-RKSSLPNSKEVPSHHPTDPVELRRLNFQTPGSDDSG--YPGNLHFSSMASHPPIPILELADHIERLKANDNLK-----FSQEYESIDPG---QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIE---GIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEER--SRV------------------KCDQYWPSR--GTETHGLVQVTLLDTVELATYCVRTFALYKNGSSE-----------KREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPD--AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIET--GENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGV-------------------EGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23468-1", "uniprot_id": "PTPRD_HUMAN", "id": "P23468-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------M--VHVARLLLLLLTFFLR-TDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNP-EPVSYYIIQHKPKNSEELYKEIDGV-----------ATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIANYELVYKDGE-HGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEF--------------------DDTTEHDMIISGLQPETSYSLTVTAYTTK-----------------------------GDGARSKPKLVSTTGAVPGKPRLVINHTQ---------------------MNTALIQWHPPVDTFGP--LQGYRLKFGRKD----------------------------------------------------------------------------------------MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSAR--------------------------------------------------------------------------------------------------NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTST-SVQLSWQPPVLA--------------------------------------------------------------------------------------------ERNGIITKYTLLYRDINIPLLPMEQLIVPA-----DTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDG------------------KMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPEVPANENIKGYYIIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAE-------SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIA----ILLYKR--------------------KRAESDS-RKSSIPNNKEIPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLK-----FSQEYESIDPG---QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIE---GIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEER--SRV------------------KCDQYWPSR--GTETHGLVQVTLLDTVELATYCVRTFALYKNGSSE-----------KREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPD--AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIET--GENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGV-------------------EGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V2N1-1", "uniprot_id": "PTPRS_MOUSE", "id": "B0V2N1-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPTWSPSV--VSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNP-DPVSYYVIEYKSKSQDGPYQIKEDI-----------TTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ---ESVIKYELLFREGD-RGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ-----------------------------EMVITNLQPETAYSITVAAYTMK-----------------------------GDGARSKPKVVVTKGAVLGRPTLSVQQTP---------------------EGSLLARWEPPADAAED-PVLGYRLQFGRED----------------------------------------------------------------------------------------AAP-ATLELAAWERRFAAP-AHKGATYVFRLAAR--------------------------------------------------------------------------------------------------GRAGLGEEAAAALSIPEDAPRGFPQILGAAGNVSAGSVLLRWLPPVPA--------------------------------------------------------------------------------------------ERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--------------------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDND-GFIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPVLLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN--------EPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIA----ILLYKN---------------KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLK-----LSQEYESIDPG---QQFTWEHSNLEANKPKNRYANVIAY------------------------------------DHSRVILQPLE---GIMGSDYINANYVD------GYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEK--SRI------------------KCDQYWPNR--GTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSE-----------KREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD--AGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEP--GEHVTGMELEFKRLASSKAHT--SRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGV-------------------EGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GAPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64605-1", "uniprot_id": "PTPRS_RAT", "id": "Q64605-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPTWRPSV--VSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNP-DPVSYYVIEYKSKSQDGPYQIKEDI-----------TTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ---ESVIKYELLFREGD-RGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ-----------------------------EMVITNLQPETAYSITVAAYTMK-----------------------------GDGARSKPKVVVTKGAVLGRPTLSVQQTP---------------------EGSLLARWEPPADAAED-PVLGYRLQFGRED----------------------------------------------------------------------------------------AAP-ATLELAAWERRFAAP-AHKGATYVFRLAAR--------------------------------------------------------------------------------------------------GRAGLGEEASAALSIPEDAPRGFPQILGAAGNVSAGSVILRWLPPVPA--------------------------------------------------------------------------------------------ERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--------------------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDND-GSIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPILLGSPEDMDLEELIQD--LSRLQRRSLRHSRQLEVPRPYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN--------EPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIA----ILLYKN---------------KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLK-----LSQEYESIDPG---QQFTWEHSNLEANKPKNRYANVIAY------------------------------------DHSRVILQPLE---GIMGSDYINANYVD------GYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEK--SRV------------------KCDQYWPNR--GTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSE-----------KREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD--AGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEP--GEHVTGMELEFKRLASSKAHT--SRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGV-------------------EGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GAPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13332-1", "uniprot_id": "PTPRS_HUMAN", "id": "Q13332-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPTWGPGM--VSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP-DPVSYYVIEYKSKSQDGPYQIKEDI-----------TTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ---ESIIKYELLFREGD-HGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWET--------------------DDTAEYEMVITNLQPETAYSITVAAYTMK-----------------------------GDGARSKPKVVVTKGAVLGRPTLSVQQTP---------------------EGSLLARWEPPAGTAED-QVLGYRLQFGRED----------------------------------------------------------------------------------------STPLATLEFPPSEDRYTASGVHKGATYVFRLAAR--------------------------------------------------------------------------------------------------SRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA--------------------------------------------------------------------------------------------ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--------------------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDAD-GFIMVYLPDGQSPVPVQSYFIVMVPLRKSRGGQFLTPLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARF--SVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKS--------EPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIA----ILLYKN---------------KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLK-----LSQEYESIDPG---QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVILQPIE---GIMGSDYINANYVD------GYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK--SRI------------------KCDQYWPNR--GTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSE-----------KREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD--AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEP--GEHVTGMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGV-------------------EGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAP8-1", "uniprot_id": "A0AB32TAP8_DANRE", "id": "A0AB32TAP8-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------------------------------------------------------------------------------------------------------------------------MMPTGHLPI--LLSLS--ALLLSPLLTGSLALSSPRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVNSQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGEINVQAKLSIIREDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLR---------SGALQIENTEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSILPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQITVKSLPKPPGTPVVTETTATSITITWDSGNP-EPVSHYIIQYRAKSPESKFETVDSI-----------TTTRYSIGGLSPNTDYEIRVSAFN--TIGQGPPSEPVEARTGEQAPASPPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLPMSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQGVPGQPTNFQVGEVSDTGVELTWEPAFEK--EGIISYELHYKEGK-DGPLGKKKFAPTSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQAKPSAPPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAG-AEVSTEHVEAPTSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDEDVPGAPPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWEM--------------------DDTAEYEMVIGGLQPDTTYSITVAAYTTK-----------------------------GDGARSKPKLVLTKGAVPGPPFLSVNQNS---------------------ESTAIIRWQPPDYVAPGLEVQGYRLQFGRKD----------------------------------------------------------------------------------------VNPLATLEFGPQELEYSISNIHRGATYIFKVSAK--------------------------------------------------------------------------------------------------SKSGFGEEATQELRVPEEVPRGYPQITEGS-NITCCSVQFSWLPPVLA--------------------------------------------------------------------------------------------ERNGAITEYTLSYQEAGTISGPKELRLPAD-----ENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAYE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADVPRNFTVKLVTKTTVLLSWKFYDSR-FPYKCTIEYH--------------------RQKSDIDARMTKTLITNLRPNTTYEFRISCQDSSDGGPKHKLVARTAPHIQIRKPELDLKRESE-STLTIVFPPLETKDLIKAIYVVVVPLKKGKGP--MRHIKSPDELDLEELLGERRLGLHHSGTTRQLKQVDGKRPYIAASFKPSSMPPSFTLGNQMMYGSFENRALDRGQEYVLFILAELNTTG-------VKAFVSSPYTDPIMAPDLDPQPLESGGDGLIWVVGPVLAVVFIICIVIA----ILLYKNS--------------KPDSSKRKESEP-RTKCLLNNADITPHHPTDPVEMRRINFQTPDSGLSSPVSEAGFDYESMMNHPPIPISELAEHTELLKANDNLK-----LSQEYESIDPG---QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVILAPIE---GITGSDYINSNYID------GYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEK--SRI------------------KCDQYWPSR--GTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSE-----------KREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD--AGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLFSYIQKLAQVEA--GEHVSGMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPYETTRVCLQPIRGL-------------------EGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2A8L5-1", "uniprot_id": "PTPRF_MOUSE", "id": "A2A8L5-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNT-EPVSFYGIQYRAAGTDGPFQEVDGV-----------ASTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQ---ERIVKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ-----------------------------ETTISGLTPETTYSITVAAYTTK-----------------------------GDGARSKPKVVTTTGAVPGRPTMMVSTTA---------------------MHTALLQWHPPKELPGE--LLGYRLQYRRAD----------------------------------------------------------------------------------------EARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAK--------------------------------------------------------------------------------------------------NRAGPGEEFEKEITTPEDVPSGFPQNLRVTGLTTS-TTELTWDPPVLA--------------------------------------------------------------------------------------------ERNGHITNYTVVYRDINSQ---LELQNVTN-----DTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--------------------GQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPQKPLPASAFIED-GRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWNTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQV--DVLPDTFTLGDKKSYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIA----ILLFKR--------------------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLK-----FSQEYESIDPG---QQFTWENSNSEVNKPKNRYANVIAY------------------------------------DHSRVLLTSID---GVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEK--SRV------------------KCDQYWPVR--GTETYGLIQVTLVDTVELATYTMRTFALHKSGSSE-----------KRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPP--GESVTAMELEFKLLANSKAHT--SRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-------------------EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64604-1", "uniprot_id": "PTPRF_RAT", "id": "Q64604-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNT-EPVSFYGIQYRAAGTDGPFQEVDGV-----------ASTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQ---ERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ-----------------------------ETTISGLTPETTYSITVAAYTTK-----------------------------GDGARSKPKVVTTTGAVPGRPTMMVSTTA---------------------MHTALLQWHPPKELPGE--LLGYRLQYRRAD----------------------------------------------------------------------------------------EARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAK--------------------------------------------------------------------------------------------------NRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTS-TTELAWDPPVLA--------------------------------------------------------------------------------------------ERNGRITNYTVVYRDINSQ---HELQNVTG-----DVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPME------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--------------------GQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLPQKPLPASAFIED-GRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQV--DELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIA----ILLFKR--------------------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLK-----FSQEYESIDPG---QQFTWENSNSEVNKPKNRYANVIAY------------------------------------DHSRVLLTSID---GVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEK--SRV------------------KCDQYWPAR--GTETYGLIQVTLVDTVELATYTMRTFALHKSGSSE-----------KRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPP--GESVTAMELEFKLLAGSKARA--SRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-------------------EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10586-1", "uniprot_id": "PTPRF_HUMAN", "id": "P10586-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAPEPAPGR--TMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNS-EPVTYYGIQYRAAGTEGPFQEVDGV-----------ATTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQ---ERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRP--------------------EESEDYETTISGLTPETTYSVTVAAYTTK-----------------------------GDGARSKPKIVTTTGAVPGRPTMMISTTA---------------------MNTALLQWHPPKELPGE--LLGYRLQYCRAD----------------------------------------------------------------------------------------EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAK--------------------------------------------------------------------------------------------------NRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTS-TTELAWDPPVLA--------------------------------------------------------------------------------------------ERNGRIISYTVVFRDINSQ---QELQNITT-----DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--------------------GQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIED-GRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTPRWSTPEELELDELLEA--IEQGGEEQRRRRRQAERLKPYVAAQL--DVLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIA----ILLFKR--------------------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLK-----FSQEYESIDPG---QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVILTSID---GVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEK--SRV------------------KCDQYWPAR--GTETCGLIQVTLLDTVELATYTVRTFALHKSGSSE-----------KRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPP--GESVTAMELEFKLLASSKAHT--SRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV-------------------EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IFW2-1", "uniprot_id": "PTPRF_DANRE", "id": "A4IFW2-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-----------------------------------------------------------------------------------------------------------------------------MVPNTCTSVPLLPVGLPLLLLLSCIQFSSQADSLPNFVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSLGEINTSAKLTVLEENQIPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDING-NGRIKQLRSG---------ALQIENSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNP-EPVSYYIIQYRAKTSDTNFQEVDGV-----------ATTRYSIGGLSPYSEYEFRVMAVN--NIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQ---DPIIKYELQYWEADSDNK-IHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKI--------------------EESTEYEAVIAGLASETSYSVTVAAYTTK-----------------------------GDGARSKAKVVTTTGAVPGKPTMIISTTV---------------------GNTALIQWQPPKDMVGE--LMGYRLRYKRLE----------------------------------------------------------------------------------------EENYEIREFSRTDDHHTVTDLHKGATYSFHLSAR--------------------------------------------------------------------------------------------------NRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTS-TTRLTWEPPALS--------------------------------------------------------------------------------------------ERNGRIIHYIVVYRDINSK---QNSTNRTS-----DTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAFATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN--------------------QQSVEVQGNLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFKTKPVLYTADQTNNGKLTINLPKVPTSAPVRCYYIVVVPVSQTS----SRQWINPDEMELDELLES--SE-GAHLRRRRRHT-DTVRPYIAAKL--STLPETFTLGDELDYSGFINRPLPNNQHFQCFVMAELKDQYPVTANEKQRTFSASPYSDPIIVQGENQMQRSVDQPEMLWVMGPVLAVVLIIIIVIA----ILLFKR--------------------KR-ASPLPKDDHSGGVKDCLLASSSDPVEMRRLNYQTPG----------------MREHPPISVSELADHIERLKANDALR-----FSQEYESIDPG---QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVVLTPVD---GVPGSDYINSNYID------GYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEK--SRV------------------KCDQYWPIR--GTETYGMIQVTMLDAVELATYSVRTFALYKNGSSE-----------KREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPD--AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQPSA--GETVTAMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGV-------------------EGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TXQ6-1", "uniprot_id": "A0AB32TXQ6_DANRE", "id": "A0AB32TXQ6-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-----------------------------------------------------------------------------------------------------------------------------MVPQTRQGS--ARHGATSLLLLLCLAVPIHADSMPSFVKTPEDQTGISGGVASFVCQAVGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGG---TPIRGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVR----VRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGMIDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNP-EPVSYYVIQYRSKISDNGFQEVDGV-----------ASTRYSIGGLSPYSEYEFRVMAVN--NIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQ---DQITKYELTYWEADSDNK-HHVIFDPAGSYAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQ-----------------------------EAVISGLLPETTYSVTVAAYTTK-----------------------------GDGARSKAKVVTTTGAVPGKPTMIISTTI---------------------GNTALIQWQPPKEMVGE--LMGYRLRYKREE----------------------------------------------------------------------------------------EDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAK--------------------------------------------------------------------------------------------------NRAGNGEEYSKEISTPEDVPSSYPQNLKVVGLTTT-TTKLAWDPPPLP--------------------------------------------------------------------------------------------ERNGKIVRYVVVYRDINSH---QNQTNGTA-----DTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEFTKNFGVKAVMKTSVLLTWEVPETYKSQVPFKILYN--------------------QQSVEVQGDLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFTTKPAHQKLDPEEGGKLAITLPEVHNSALVRWFYIVVVPVTPST----LRHWENPEDIDLDELMGN--NR-DAAVRRRRRQTQDFLRPYIAAKL--ESLPERFVLGDEKTYSNYYNKPLPGQQQYRTFILAALKD--------RDSTFTVSPFSEPMMVKLHSGMSRHVEDPEMLWVMGPVLAVVLIIIIVIA----ILLFKR--------------------KR-TSPSAKDEHSAGVKDHLLAHSSDPVEMRRLNYQTQGSSAFN-----CPSTSRMREHPPVSVCALADHIERLRANDSLR-----FSQEYESVDPG---QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVVLTPVD---GVPGSDYINGNYID------GYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEK--SRV------------------KCDQYWPSR--GTETYGMIQVSMLDTVELATYSVRTFALYKNGSSE-----------KREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPD--AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQAPP--GDTVTAMELEFKKLANSKAHT--SRFISASLPCNKFKNRLVNIMPFESSRVCLQPIRGV-------------------EGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q0T4-1", "uniprot_id": "A0A8M9Q0T4_DANRE", "id": "A0A8M9Q0T4-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------------------------------------------------------------------------------------------------------------------------MARGHMIYR---SAYQPLLLILLSALQLAHMQSAPRFTRTPTDQIGVQGGVASFVCQATGDPQPKITWSRKGKKVTNQRFEVIEFEDGSGSALRVQPLRTPRDEAIYECVASNEIGEITASTRLSVLREDQLPAGFPSIDMGPQLKVVERSRTATMLCAASGTPDPEITWFKDFLPIDTHT-HGRIKQLRSGG---TPIRGALQIDQSEETDQGKYECVATNSEGTRYSTPANLYVRELRDVRRIPPRFSVPPMDYEIMPGGSVNITCQAVGVPMPYVKWMLGAEDLTPEDDMPIGRNVLELTNVRQSANYTCVAMSTLGVIETVSQITVKALPNPPGSPVVMERSATSITLMWDSGNP-HPVSYYIIQYRPSSSTDPFKEIDAI-----------ATTRYSVGGLSPYSHYHFRVVAVN--SIGRGAPSPTVDARTAEQAPSSPPRRVRGRMLSGSTAMVQWEEPEEANGQVVGYRVYYTSDSSLSVSQWEKEMVRGANFLNIRDLTPNKTYYIRVLAFTAVGDGPLSSDLHIIAKTGVPSQPTELKAEVKSETSILLSWIPPAHSGTDAITGYELIYRLGD--QPEQKITFDPSSSYLLKNLKPFSTYVFQLAARSKHGLGAFTSEITVQTPQTQSIPPPQDVTCTSPSSTSLLLSWASPPTD-ENGIVTGYSIRYVAVERDKDPVQKISDIPSNCFRYRIEGLKKGTLYSVTIAAHTDNGQGPESLPILVRTEEDVPSAPPRGVDVVVLNATSARVSWKPPVAERQHGKIRGFQVTYARRTAGERTVSPRIREHLLRDPQQPQ--------------------NDSIEHEVILTDLWPNTEYSVTVAAFTSK-----------------------------GDGARSKPIVIRTKPSLPGMPLLTVVSSE---------------------DSTALLKWQPPPTGLSP--VLGYRLSYGQADPS--------------------------------------------------------------------------------------SDTFMVQELGAEERSYTVSSLSAGVLYVFRLAAR--------------------------------------------------------------------------------------------------TVWGYGSSAQVTLLIPNVVQTTTDGMITDLMTTEGQTMSVQENVPILANLTA-------------------------------------------------------------------------ESINSSSAILRWERPKNYDGIQGYRVWFAVTYSNGTDIAMESDVS-----ETTVVLHGLRANTEYVARVCMLSKQGPGPYSLPISIKTQPAE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVFAVNFKVKAAMKSSVLLTWESRTTSNKAQSLIISYGD-------------------GESVEVDGRLGQKLVTKLKPQSLYNFLLTSKSDSTGGLQHRTDAMTAPNLMTRKPQLLDKTSSQ-SIAILQLPTVQGQANVRGFYILVVPLKRQRAGNFQNMWSDPDEMNLDELLRE---INGTGRSVRLRRQAEAK-PYITAHF--QNLPAEFKLGDGHVYGAFMNRPLVNGQEYVCFVLAILELG-------QNTVYSTSPFSDAVLFSDVEPQPIVDEEEGLLWVVGPVLAVIFIISIVIL----ILLFKS----------------KPDRKRAELEGRKCSFLSSGKAMSSQHPSDPVELRRINFPTAG----------------MTSHPPVSVSELPAHIERMKANDSLR-----FSQEYESIDPG---QQFSWEHSNLEINKPKNRYANVIAY------------------------------------DHTRVALTNTD---GVAGGDYINANFID------GYRRQGAYIATQGPMPDTFSDFWRMVWEQHTANVIMITKLEEK--SRMPSYFFSK----------NKCDQYWPSR--GTETYGLMQVSLLDTVELATYCVRTFALFKSGSGE-----------KREVRQFQFTAWPDQGVPEHPTPFLAFLRRVKACNPPD--AGPIVVHCSAGVGRTGCFIVIDAMLERVKQEKTLDIYGHVTLMRSQRNYMVQTEEQYVFIYEALLEAVSCGNTEVPARNLYAYIQRLSQTEP--PEHISGMEQEFKRLANAKAHN--SRFVSASLPCNKFKNRLVNIMPYESTRVCLQPIRGV-------------------EGSDYVNGSFIDGYRQQRAYIATQGPLAETVEDFWRMLWEHNSTIVVMLTKLREMGRE-KCHQYWPSDRSAR-YQYFVVDPMAEYNMPQYILREFKVTDAR-----DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHK-TKEQFGQDGP-------ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEEQYQFCYRAGLEYLGSFDHYAT---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18052-1", "uniprot_id": "PTPRA_MOUSE", "id": "P18052-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILVLFGSGLIHVSANNATTVSPSLGTTRLIKTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTELAKEENKTSNSTSSVISLSVAPTFSPNLTLEPTYV----------------------------------------------TTVNSSHSDNGTRRAASTESGGTTISPN---GSWLIEN----------------------------------------------------------------------------------------QFTDAITEPWEGN------------------------------SSTAATTPETFPP---------ADETPIIAVMVALSSLLVIVFIIIVLY----MLRFKK---------------------------YKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSP-------------STNRKYPPLPVDKLEEEINRRMADDNKL-----FREEFNALPACP--IQATCEAASKEENKEKNRYVNILPFLSLAVSKDAVKALNKTTPLLERRFIGKSNSRGCLSDDHSRVHLTPVE---GVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKEC--------------------KCAQYWPDQ--GCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKP-------QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY--AGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIP--GTSNNGLEEEFKKLTSIKIQN--DKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGE-------------------ENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQE-KCAQYWPSDGLVS-YGDITVELKKEEECESYTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEV-GIPSDGKGMINIIAAVQK-QQQQSG-NHP-------ITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03348-1", "uniprot_id": "PTPRA_RAT", "id": "Q03348-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTESAKEENKTSNSTSSVISLSVTPTFSPNLTLEPTYV----------------------------------------------TTVNSSHSDNGTKRAASTESGGTTISPNGTYGTWLTDN----------------------------------------------------------------------------------------QFTDARTEPWEGN------------------------------SSSAATTPETFPP---------ADETPIIAVMVALSSLLVILFIIIVLY----MLRFKK---------------------------YKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSP-------------STNRKYPPLPVDKLEEEINRRMADDNKL-----FREEFNALPACP--IQATCEAASKEENKEKNRYVNLLPY------------------------------------DHSRVHLTPVE---GVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKEC--------------------KCAQYWPDQ--GCWPYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKP-------QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY--AGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLDTHLQKIYNKIP--GTSNNGLEEEFKKLTSIKIQN--DKMRTGYLPANMKKNRVLQIIPYEFNRVIIPVKRGE-------------------ENTDYVNASFIDPYRQKDSYIASQGPLLHTTEDFWRMIWEWKSCSIVMLTELEERGQE-KCAQYWPSDGLVS-YGDITVELKKEEECESYTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEV-GIPSDGKGMINIIAAVQK-QQQQSG-NHP-------ITVHCSAGAGRTGTFCALSTVLECVKAEGILDVFQTVKTLRLQRPHMVQILEQYEFCYKVVQEYIDAFSDYANFK-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18433-5", "uniprot_id": "PTPRA_HUMAN", "id": "P18433-5", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTYL----------------------------------------------TTVNSSDSDNGTTRTASTNSIGITISPN---GTWLPDN----------------------------------------------------------------------------------------QFTDARTEPWEGN------------------------------SSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLY----MLRFKK---------------------------YKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSP-------------STNRKYPPLPVDKLEEEINRRMADDNKL-----FREEFNALPACP--IQATCEAASKEENKEKNRYVNILPY------------------------------------DHSRVHLTPVE---GVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKEC--------------------KCAQYWPDQ--GCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKP-------QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY--AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIP--GTSNNGLEEEFKKLTSIKIQN--DKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGE-------------------ENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQE-KCAQYWPSDGLVS-YGDITVELKKEEECESYTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQK-QQQQSG-NHP-------ITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23469-1", "uniprot_id": "PTPRE_HUMAN", "id": "P23469-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLCPLLLVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSLPLARALRGNETTADSNE----------------------------------------------TTTTSGPPDPGAS------------------------------------------------------------------------------------------------------------------------------------------------------------------QP--------------------LLAWLLLPLLLLLLVLLLAAY----FFRFRK---------------------------QRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSP-------------SGPKKYFPIPVEHLEEEIRIRSADDCKQ-----FREEFNSLPSGH--IQGTFELANKEENREKNRYPNILPN------------------------------------DHSRVILSQLD---GIPCSDYINASYID------GYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEE--------------------KCHQYWPDQ--GCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAP--------RLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVH--AGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTT--HFDKIGLEEEFRKLTNVRIMK--ENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQ-------------------EYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQD-KCYQYWPTEGSVT-HGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEI-GIPAEGKGMIDLIAAVQK-QQQQTG-NHP-------ITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06800-4", "uniprot_id": "PTPRC_MOUSE", "id": "P06800-4", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMGLWLKLLAFGFALLDTEVFVTGQTPTPSDE-LSTTENALLLPQSDPLPARTTESTPPSISE-------------------RGNGSSETTYHP---------------------------------------------GVLSTLLPHLSPQPDSQTPSAGGADTQTFSS---------------QADNPTLTPAPGGGTDPPGVPGERTVPGTIPADTAFPVD-TPSLARNSSAASPTHTSNVSTTDISSGASLTTLTPSTLG-LASTDPPSTTIAT-TTKQTCAAMFGNITVNYTYESSNQTFKADLKDVQNAKCG-----------NEDCEN-VLNNLEECSQIKNISVS--NDSC-APATTIDLYVPPGTDKFSLHDCTPKEKANTSICLEWKTKNLDFRKCNSDNISYVLHCEPENNTKCIRRNTFIPE------------------------------------------------------------------------------------------------RCQLDNLRAQTNYTCVAEILYRGVK-------------------------------------------------------------------------------------------------------LVKNVINVQTDLGIPET-PKPSCGDPAARKTLVSWPEPVSKPESASKPHGYVLCYKNN-SEKCKSLPNNVTS------------------------------------FEVESLKPYKYYEVSLLAYVNG-----------------------------KIQRNGTAEKCNFHTKADRPDKVNGMKTS---------------------RPTDNSINVTCGPPYET----------------------------------------------------------------------------------------------------------------------------NGPKTFYILVVR--------------------------------------------------------------------------------------------------SGGSFVTKYNKTN-------------------------------------------------------------------------------------------------------------------------------------------------------------------CQFYVDNLYYSTDYEFLVSFHNGVYEGDSVIRNESTNFN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKALIIFLVFLIIVTSIALLVVLYK---------------------------------------------IYDLRKKRSSNLDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QELVERDDEKQLMD-------------------VEPIHSDILLETYKRKIADEGRL-----FLAEFQSIPRVF--SKFPIKDARKPHNQNKNRYVDILPY------------------------------------DYNRVELSEIN---GDAGSTYINASYID------GFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRN--------------------KCAEYWPSMEEGTRAFKDIVVTINDHKRCPDYIIQKLNVAHKKEKATG----------REVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFF--SGPIVVHCSAGVGRTGTYIGIDAMLEGLEAEGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHSCLHNMKKRDP--PSDPSPLEAEYQRLPSYRSWR---TQHIGNQEENKKKNRNSNVVPYDFNRVPLKHELEMSKESEPESDESSDDDSDSEETSKYINASFVMSYWKPEMMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELVNGDQE-VCAQYWG-EGKQT-YGDMEVEMKDTNRASAYTLRTFELRHSK-----RKEPRTVYQYQCTTWKGE-ELPAEPKDLVSMIQDLKQKLP-KASPEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETEDVVDVFQVVKSLRKARPGVVCSYEQYQFLYDIIASIYPAQNGQVKKTNSQ-DKIEFHNEVDGGKQDANCVRPDGPLNKAQEDSRGVGTPEPTNSAEEPEHAANGSASPAPTQSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04157-1", "uniprot_id": "PTPRC_RAT", "id": "P04157-1", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLWLKLLAFSLALLGPEVFVTGQG-TTDDG-LDTTE-IVLLPQTDPLPARTTEFTPPSISE-------------------RGNGSSETTYLP---------------------------------------------GFSSTLMPHLTPQPDSQTPSARGADTQTLSS---------------QADLTTLTAAPSGETDPPGVPEESTVP------ETFPGG-TPILARNSTAPSPTHTSNVSTTDISSGANLTTPAPSTLG-FASNTTTSTEIATPQTKPSCDEKFGNVTVRYIYDDSSKNFNANLEGDKKPKCE-----------YTDCEK-ELKNLPECSQ-KNVTLS--NGSC-TPDKIINLDVPPGTHNFNLTNCTPDIEANTSICLEWKIKNK--FTCDIQKISYNFRCTPEMKTFALDKHGTL----------------------------------------------------------------------------------------------------WLHNLTVRTNYTCAAEVLYNNVI-------------------------------------------------------------------------------------------------------LLKQDRRVQTDFGTPEMLPHVQCKNSTNSTTLVSWAEPAS------KHHGYILCYKKTPSEKCENLANDVNS------------------------------------FEVKNLRPYTEYTVSLFAYVIG-----------------------------RVQRNGPAKDCNFRTKAARPGKVNGMKTS---------------------RASDNSINVTCNSPYEI----------------------------------------------------------------------------------------------------------------------------NGPEARYILEVK--------------------------------------------------------------------------------------------------SGGSLVKTFNQST-------------------------------------------------------------------------------------------------------------------------------------------------------------------CKFVVDNLYYSTDYEFLVYFYNGEYLGDPEIKPQSTSYN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKALIIFLVFLIIVTSIALLVVLYK---------------------------------------------IYDLRKKRSSNLDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QELVERDEEKQLIN-------------------VDPIHSDLLLETYKRKIADEGRL-----FLAEFQSIPRVF--SKFPIKDARKSQNQNKNRYVDILPY------------------------------------DYNRVELSEIN---GDAGSTYINASYID------GFKEPRKYIAAQGPRDETVDDFWKMIWEQKATVIVMVTRCEEGNRN--------------------KCAEYWPCMEEGTRTFRDVVVTINDHKRCPDYIIQKLSIAHKKEKATG----------REVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFF--SGPIVVHCSAGVGRTGTYIGIDAMLESLEAEGKVDVYGYVVNLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHSCLQNLKKRDP--PSDPSPLEAEYQRLPSYRSWR---TQHIGNQEENKKKNRSSNVVPYDFNRVPLKHELEMSKESEAESDESSDEDSDSEETSKYINASFVMSYWKPEMMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELMSGDQE-VCAQYWG-EGKQT-YGDMEVMLKDTNKSSAYILRAFELRHSK-----RKEPRTVYQYQCTTWKGE-ELPAEPKDLVTLIQNIKQKLP-KSGSEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETEDVVDVFQVVKSLRKARPGMVGSFEQYQFLYDIMASIYPTQNGQVKKANSQ-DKIEFHNEVDGAKQDANCVQPADPLNKAQEDSKEVGASEPASGSEEPEHSANGPMSPALTPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08575-3", "uniprot_id": "PTPRC_HUMAN", "id": "P08575-3", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFE-------------------RENDFSETTTSLSPDNTSTQVSPDSLDNASAF----------------------NTTGVSSVQTPHLPTHADSQTPSAG-TDTQTFSG---------------SAANAKLNPTP-GSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECG-----------NNTCTNNEVHNLTECKN-ASVSIS--HNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIET--FTCDTQNITYRFQCG----NMIFDNKEIK-----------------------------------------------------------------------------------------------------LENLEPEHEYKCDSEILYNNHK-------------------------------------------------------------------------------------------------------FTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQR------SFHNFTLCYIKETEKDCLNLDKNLIK------------------------------------YDLQNLKPYTKYVLSLHAYIIA-----------------------------KVQRNGSAAMCHFTTKSAPPSQVWNMTVS---------------------MTSDNSMHVKCRPPRDR----------------------------------------------------------------------------------------------------------------------------NGPHERYHLEVE--------------------------------------------------------------------------------------------------AGNTLVRNESHKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------CDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKALIAFLAFLIIVTSIALLVVLYK---------------------------------------------IYDLHKKRSCNLDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QELVERDDEKQLMN-------------------VEPIHADILLETYKRKIADEGRL-----FLAEFQSIPRVF--SKFPIKEARKPFNQNKNRYVDILPY------------------------------------DYNRVELSEIN---GDAGSNYINASYID------GFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRN--------------------KCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATG----------REVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFF--SGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDP--PSEPSPLEAEFQRLPSYRSWR---TQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQE-ICAQYWG-EGKQT-YGDIEVDLKDTDKSSTYTLRVFELRHSK-----RKDSRTVYQYQYTNWSVE-QLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05909-1", "uniprot_id": "PTPRG_MOUSE", "id": "Q05909-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQDSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGDEYQELQLDGFDNESSN----------KTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWG-------------------HSNG-SAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENR----------IIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS--------------------------------------------------------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTASAAS---------------------------------------------------------------------------------------------------------------------------KQAGRTVLATTEALASPGPDVH----------------------------------------------------------------------------------------------------SAPSKDSEGTEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------EEKSESEDGEREHEEE-EKDSEKKEKSEATHTAAESDRTAPAPTPSSPHRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAEGGHQTIPGRRQDHSAPATDQPG---HVAPDLDPLVDTATQVPP-------------------------------------------------TATEEHYSGSDPRRPEMPSKKPMSRGDRFSEDSK---------------------------------------------------------------------------------------------------------------------------------------FITVNPAEKNTSGMLSR-----PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESVPIIPIPD-----------------DMEAIPVKQFGKHIGELYSNSQHG-----FSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAY------------------------------------DHSRVKLRPLPGKDSKHS-DYINANYVD------GYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRR--------------------KCDQYWPTE--NTEEYGNIIVTLKSTKVHACYTVRRLSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPD--MGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETAVSSSQLHSYVNSILIPGV--GGK-TRLEKQFKLITQCNAKY--VECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKG-------------------TDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEAL------TRDGP-------TIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLISTKENGNGPMTGDKNGAVLTAEESDPAESMESLV-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP13-1", "uniprot_id": "F1LP13_RAT", "id": "F1LP13-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQGSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSN----------KTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWG-------------------HSNG-SAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENR----------IIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHISPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS--------------------------------------------------------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTASAAS---------------------------------------------------------------------------------------------------------------------------KQAGRPVLATTEALASPGPDGD----------------------------------------------------------------------------------------------------SAPTKDGEGAEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------EEKSESEDGEREQEEE-EKDSEKKEKSEATHTAAESDQTAPAPTPSSPHRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQEGGHQTIPGHRQDHSAPVTDQPG---HVDPGLDTLVDTATQVPP-------------------------------------------------TATEEHYSGSDPKRPEMPSKKPISRGDRFSEDSK---------------------------------------------------------------------------------------------------------------------------------------FITVNPAEKNTSGMISR-----PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPD-----------------DMEAIPVKQFGKHIGELYSNSQHG-----FSGDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAY------------------------------------DHSRVKLRPLPGKDSKHS-DYINANYVD------GYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRR--------------------KCDQYWPTE--NTEEYGNIIVTLKSTEVHACYTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPD--MGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGV--GGK-TRLEKQFKLITQCNAKY--VECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKG-------------------TDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEAL------ARDGP-------TIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTGDKNGAVLTAEESDPAESMESLV-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23470-1", "uniprot_id": "PTPRG_HUMAN", "id": "P23470-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSN----------KTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWG-------------------HSNG-SAGSEHSINGRRFPVEMQIFFYNPDDFDSFQTAISENR----------IIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVRDSWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS--------------------------------------------------------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTAASAS---------------------------------------------------------------------------------------------------------------------------KQAARPVLATTEALASPGPDGD----------------------------------------------------------------------------------------------------SSPTKDGEGTEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------DEKSESEDGEREHEEDGEKDSEKKEKSGVTHAAEERNQTEPSPTPSSPNRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-EGGHQTIPGHEQDHTAVPTDQTGGRRDAGPGLDPDMVTSTQVPP-------------------------------------------------TATEEQYAGSDPKRPEMPSKKPMSRGDRFSEDSR---------------------------------------------------------------------------------------------------------------------------------------FITVNPAEKNTSGMISR-----PAPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPD-----------------DMEAIPVKQFVKHIGELYSNNQHG-----FSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAY------------------------------------DHSRVKLRPLPGKDSKHS-DYINANYVD------GYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRR--------------------KCDQYWPTE--NSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPE--TGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSILIPGV--GGK-TRLEKQFKLVTQCNAKY--VECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKG-------------------TDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEAL------TRDGP-------TIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAMLSLVSTKENGNGPMTVDKNGAVLIADESDPAESMESLV-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQH6-1", "uniprot_id": "A0A8M1QQH6_DANRE", "id": "A0A8M1QQH6-1", "name": "protein-tyrosine-phosphatase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MWRLRGPCRLGMLCLTLSALLIQPISCHPAS------HVETVRRGSSANQRERRASGEPYWAYSGTYGPRRWASAYPECGERNQSPVDILDPETQVSQECQELTLDGFETKSSN----------RTTMKNTGKTVSIVLKNDYFVRGAGLPGRFKAEKVEFHWG-------------------STNG-SAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERR----------IIAAMAVFFQVATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGSYYRYTGSLTTPPCSKVVEWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIFKSALMDAW---MPETMASAADTETSRVCSSIPDNMKLHPLNRTALVLTWDRPSAVYHPPIVGFLVSYSWVKDEMPFEKTFTQSSEHSTRAVITLVSPDVLYLFRVQALCQRDQRSDFSQTLLFKANTTR----------------------------------------------------------------------------------------------IFEGTRIVKTGMPTVS--------------------------------------------------------------------------------------------------------------PASSADMAPISSGSSTWTSAGLPFS------------------------FVSMATGMGPPS------------------------------------------------SGGQATVASVVTSTLLAG---------------------------------LGFSGSVISSLPGSFWPTH---------------------------STNTGPSP---------------------------------------------------------------------------------------------------------------------------TQHP----ATPTAENSPSED---------------------------------------------------------------------------------------------------------STDTQNKLEEEE--------------------------------------------------------------------------------------------------------------------------------------------------------EHKKEDDEEEEEEEEEEEQRDEEKKKKGKDVTVKDKKQTVQKPTAPIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSKHRDRERPDAESST---LTPAEVEEQVSGATERPD-------------------------------------------------AEDSSKATWQDDNDMQIPSSSTESSKLSDEEKAN---------------------------------------------------------------------------------------------------------------------------------------WPYYINTERNSISTVSRD--SVSSSSRMEWIIPLMVVSALTLLCLIMLLAVLVYWR-----------------------------RFFQTAHFYIEDRNSPRVIHNDSFPIISTAD-----------------DLEAMPVRQFIKHIMELHSNNRHG-----FSQEFDEVQHCTSEMKITAEHSNHPENKHKNRYINIVAY------------------------------------DHSRVKLQQLPGKDSKHS-DYINANYVD------GYKRARAYIAAQGPLKSTFEDFWRMIWEQNTTVIVMITNLVEKGRR--------------------KCDQYWPSE--NSEVYGNIMVTLKSTKVYAYYTLRHFIVRNSKLKKGQKG----RQNERLVLQYHYTQWPDMGVPEYTLPVLKFISRSTVTHASS--TGPVLVHCSAGVGRTGTYIVIDSMLKQIKDRGSVNVLGFLKHIREQRNYLVQTEEQFIFIHDALMEAVLSKDTEVSAWQLHTYTNSLLTPSP--TGH-TRMDKHFKLLTQCNAHL--AECLSGQKECNKEKNRTSAVLPTERARVALSPLPGLKG-------------------TDYINASYIMGYYRSNEFIITQHPLPHTTTDFWRMIWDHNAQVIVMLPDNLGLTEDEF--VYWPSREEPMNCIAFTVTLINTDRLCLSNEEQLIIHDFILEATQDDYVLEVRHFQCPNWPDPDASISSTFELINIIKEEAM------TRDGP-------TIVHDEFGAVSAGTFCALTTLSQQLENESAVDVYQVAKMINLMRPGVFTEIEHYHYLYQAMLSLVSSKDFRFGFNYMDKFAG--KADESNQAESMESLV-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B9EKR1-1", "uniprot_id": "PTPRZ_MOUSE", "id": "B9EKR1-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRILQS----FLACVQLLC-------------------LCRLDWAYGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPICNSPKQSPINIDEDLTQVNVNLKKLKFQGWEKASLE----------NTFIHNTGKTVEINLTNDYYLSGGLSEKVFKASKITFHWG-------------------KCNVSSEGSEHSLEGQKFPLEMQVYCFDADRFSSFEEAVKGKG----------RLRALSILFEVGVEENLDYKAIIDGTESVSRFGKQAALDPFVLQNLLPNSTDKYYIYNGSLTSPPCTDTVEWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEVVCSSEPENVQADPENYTSLLVTWERPRVVYDAMIEKFAVLYQPLAGNDQAKHEFLTDGYQDLGAILNNLLPNMSYVLQIVAVCSNGLYGKYSDQLIVDMPTEDAELDLFPELIGTEEIIKEEEYGKDNEEDTGLNPGRDSVTNQIRKKEPQVSTTTHYNHMGTKYNEAKTNRSPTRGSEFSGKSDVPNTSPNSTSQHVAEFETERGISLPSQTGTNLPPHNVEGTSASLNSGSKTLFIFPQMNLSGTAESLNTVPITEYK--------------------------------------------------EVSADVSEEENFLTDFKLDTGADDSSGSSPSTSTVPFSSDNLSHGYITSSDMPEAITYDVLKPGSTRNAPEDSAPSGSEESLKDPSLEGSVWFPGSTDLTTQSETGSGRESFLQVNSTDIQIDESRETTESFSPDATVSQDPSVTDMGMPHYSTFAYLPTEVTPQAFTPSSRPLDLAPTINILHSQTTQPVYNGETPLQPSYSSEVFPLATPLLLDNQTLNTTPAASSSDSALHATPVSPSVGVSFESILSSYDDAPLLPFSSASFSSEMFRHLHTVSQTLPQVTSAAERDELSLHASLLVARGDLLLEPSLVQYSDVASHQATTRAASDTLGFGSESAVFYKTSMVSQIESPRSDVVMHAYSSGPEPSYTV---EGSHHVPTVSYSSAMPLHGSVDVSDQGSLLINPSHISMPESSFITPTASLLQPPPALSGDGEWSGASSDSELLLPDADGLRTLNISSPVSVAEFTYTTSVFADGIKPLSKSEMMYGNETELKMSSFSDMAYPSKSTVVPKMSDVVHKWSESLKETSVSISSMKSVFPESLVYPTTKGFEQGVSHVPEIIFPVQPTHTASQASGDTWLKPGLSANSEAAFSDTASREVVHPSTQPLLYEAATPFNTEALLQPSFQASDVDTLLKTALPSVPSDPILAGTPQVEQSSSSVSHPMASESGSSESMLHFTSVPILDISP-SKVHSTPLQGLTVPHSSKKFSEQGLLKSKSPQQVLPSLFSNDEFFQSAHLDVSQAYPPKGRHAFVTPVLSIDEPQNTLINKLVYSEDIFSSTEISITDKVLTGLPTLASDVLSSTDHSVPLGSGPISLTMVSPNRDDSVTTAKLLLPSTATSKLTQSARSDADLVGGGEDGDDYDD--DDYDDIDRGRFPVNKCMSCLPYRESREKVMNDSDTQESSLVDQSDPISPLLFENTEEENGGTGVTR-----VDKSP----PPSMLPQNHNDGKEDSDIQMGSAVLPHTPGSKAWAVLTSDEESGSGQGTSDSLNDNETSTDFSFPDVNEKDT-------------------------------------------------------------------------------------------------------DGVLETDDTGIAPGSPRSSTPSVTSGHSGVSNSSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDNTSPRVISTPPTPIFPISD-----------------DIGAIPIKHFPKHVADLHASNGFTEEFETLKEFYQEVQSCTADLGITADSSNHPDNKHKNRYVNIVAY------------------------------------DHSRVKLTQLAEKDGKLT-DYINANYVD------GYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRR--------------------KCDQYWPTD--GSEEYGSFLVNQKSVQVLAYYTVRNFTLRNTKLKKGSQK---GRSSGRLVTQYHYTQWPDMGVPEYSLPVLAFVRKAAQAKRHA--VGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVPDSHIHSYVNTLLIPGP--TGK-TKLEKQFQLLSQSNILQ--SDYSTALKQCNREKNRTSSIIPVERSRVGISSLSGEG--------------------TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISIIKEEAA------NRDGP-------MIVHDEHGGVTAGTFCALTTLMHQLEKENAMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVSTRQEENPSTSLDSNGAALPD--GNIAESLESLV-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62656-1", "uniprot_id": "PTPRZ_RAT", "id": "Q62656-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRILQS----FLACVQLLC-------------------VCRLDWAYGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPICNSPKQSPINIDEDLTQVNVNLKKLKFQGWEKPSLE----------NTFIHNTGKTVEINLTNDYYLSGGLSEKVFKASKMTFHWG-------------------KCNVSSEGSEHSLEGQKFPLEMQIYCFDADRFSSFEETVKGKG----------RLRALSILFEIGVEENLDYKAIIDGTESVSRFGKQAALDPFILQNLLPNSTDKYYIYNGSLTSPPCTDTVEWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEAVCSSEPENVQADPENYTSLLITWERPRVVYDTMIEKFAVLYQPLEGNDQTKHEFLTDGYQDLGAILNNLIPNMSYVLQIVAICSNGLYGKYSDQLIVDMPTEDAELDLFPELIGTEEIIKEENYGKGNEEDTGLNPGRDSATNQIRKKEPQVSTTTHYNHMGTKYNEAKTNRSPTRGSEFSGKSDVLNTSLNPTSQQVAEFNPEREMSLPSQIGTNLPPHSVEGTSASLNSGSKTLLVFPQMNLSGTAESLNMVSITEYK--------------------------------------------------EVSADLSEEENLLTDFKLDSGADDSSGSSPASSTVPFSTDNLSHGYTSSSDTPEAVTYDVLRPESTRNALEDSAPSGSEESLKDPSLEGSVWFPGSTDLTTQSETGSGREGFLQVNSTDFQVDESRETTETFSPDATASRGPSVTDMEMPHYSTFAYPPTEVTSHAFTPSSRPLDLAPTSNILHSQTTQPVYNGETPLQPSYSSEVFPLVTPLLLDNQTLNTTPAASSSDSALHATPVFPSVGVSFDSILSSYDDAPLLPFSSASFSSDLFHHLHTVSQTLPQVTSAAERDELSLHASLLVAGGDLLLEPSLVQYSDVMSHQVTIHAASDTLEFGSESAVLYKTSMVSQIESPSSDVVMHAYSSGPETSYAI---EGSHHVLTVSSSSAIPVHDSVGVADQGSLLINPSHISLPESSFITPTASLLQLPPALSGDGEWSGASSDSELLLPDTDGLRTLNMSSPVSVADFTYTTSVSGDDIKPLSKGEMMYGNETELKMSSFSDMAYPSKSTVVPKMSDIVNKWSESLKETSVSVSSINSVFTESLVYPITKVFDQEISRVPEIIFPVKPTHTASQASGDTWLKPGLSTNSEPALSDTASSEVSHPSTQPLLYEAASPFNTEALLQPSFPASDVDTLLKTALPSGPRDPVLTETPMVEQSSSSVSLPLASESASSKSTLHFTSVPVLNMSP-SDVHPTSLQRLTVPHSREEYFEQGLLKSKSPQQVLPSLHSHDEFFQTAHLDISQAYPPKGRHAFATPILSINEPQNTLINRLVYSEDIFMHPEISITDKALTGLPTTVSDVLIATDHSVPLGSGPISMTTVSPNRDDSVTTTKLLLPSKATSKPTHSARSDADLVGGGEDGDDYDD--DDYDDIDSDRFPVNKCMSCSPYRESQEKVMNDSDTQESSLVDQSDPISHLLSENTEEENGGTGVTR-----VDKSPDKSPPPSMLPQKHNDGREDRDIQMGSAVLPHTPGSKAWAVLTSDEESGSGQGTSDSLNDNETSTDFSFPDVNEKDA-------------------------------------------------------------------------------------------------------DGVLEADDTGIAPGSPRSSTPSVTSGHSGVSNSSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDNTSPRVISTPPTPIFPISD-----------------DIGAIPIKHFPKHVADLHASNGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYVNIVAY------------------------------------DHSRVKLTQLAEKDGKLT-DYINANYVD------GYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRR--------------------KCDQYWPTD--GSEEYGSFLVNQKNVQVLAYYTVRNFTLRNTKIKKGSQK---GRSSGRLVTQYHYTQWPDMGVPEYSLPVLAFVRKTAQAKRHA--VGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVPDSHIHSYVNTLLIPGP--SGK-TKLEKQFQLLSQSNILQ--SDYSTALKQCNREKNRTSSIIPVERSRVGISSLSGEG--------------------TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISIIKEEAA------NRDGP-------MIVHDEHGGVTAGTFCALTTLMHQLEKENSMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVSTRQEENPSTSLDSNGAALPD--GNIAESLESLV-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23471-1", "uniprot_id": "PTPRZ_HUMAN", "id": "P23471-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRILKR----FLACIQLLC-------------------VCRLDWANGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLE----------NTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWG-------------------KCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKG----------KLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEAVCSSEPENVQADPENYTSLLVTWERPRVVYDTMIEKFAVLYQQLDGEDQTKHEFLTDGYQDLGAILNNLLPNMSYVLQIVAICTNGLYGKYSDQLIVDMPTDNPELDLFPELIGTEEIIKEEEEGKDIEEGAIVNPGRDSATNQIRKKEPQISTTTHYNRIGTKYNEAKTNRSPTRGSEFSGKGDVPNTSLNSTSQPVTKLATEKDISLTSQTVTELPPHTVEGTSASLNDGSKTVLRSPHMNLSGTAESLNTVSITEY----------------------------------------------------------EEESLLTSFKLDTGAEDSSGSSPATSAIPFISENISQGYIFSSENPETITYDVLIPESARNASEDSTSSGSEESLKDPSMEGNVWFPSSTDITAQPDVGSGRESFLQTNYTEIRVDESEKTTKSFSAGPVMSQGPSVTDLEMPHYSTFAYFPTEVTPHAFTPSSRQQDLVSTVNVVYSQTTQPVYNGETPLQPSYSSEVFPLVTPLLLDNQILNTTPAASSSDSALHATPVFPSVDVSFESILSSYDGAPLLPFSSASFSSELFRHLHTVSQILPQVTSATESDKVPLHASLPVAGGDLLLEPSLAQYSDVLS---TTHAASETLEFGSESGVLYKTLMFSQVEPPSSDAMMHARSSGPEPSYALSDNEGSQHIFTVSYSSAIPVHDSVGVTYQGSLFSGPSHIPIPKSSLITPTASLLQPTHALSGDGEWSGASSDSEFLLPDTDGLTALNISSPVSVAEFTYTTSVFGDDNKALSKSEIIYGNETELQIPSFNEMVYPSESTVMPNMYDNVNKLNASLQETSVSISSTKGMFPGSLAHTTTKVFDHEISQVPENNFSVQPTHTVSQASGDTSLKPVLSANSEPASSDPASSEMLSPSTQLLFYETSASFSTEVLLQPSFQASDVDTLLKTVLPAVPSDPILVETPKVDKISSTMLHLIVSNSASSENMLHSTSVPVFDVSPTSHMHSASLQGLTISYASEKY-EPVLLKSESSHQVVPSLYSNDELFQTANLEINQAHPPKGRHVFATPVLSIDEPLNTLINKLIHSDEILTSTKSSVTGKVFAGIPTVASDTFVSTDHSVPIGNGHVAITAVSPHRDGSVTSTKLLFPSKATSELSHSAKSDAGLVGGGEDGDTDDDGDDDDDDRGSDGLSIHKCMSCSSYRESQEKVMNDSDTHENSLMDQNNPISYSLSENSEEDNRVTSVSSDSQTGMDRSPGKSPSANGLSQKHNDGKEENDIQTGSALLPLSPESKAWAVLTSDEESGSGQGTSDSLNENETSTDFSFADTNEKDA-------------------------------------------------------------------------------------------------------DGILAAGDSEITPGFPQSPTSSVTSENSEVFHVSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDSTSPRVISTPPTPIFPISD-----------------DVGAIPIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAY------------------------------------DHSRVKLAQLAEKDGKLT-DYINANYVD------GYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRR--------------------KCDQYWPAD--GSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQK---GRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHA--VGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGP--AGK-TKLEKQFQLLSQSNIQQ--SDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEG--------------------TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEEAA------NRDGP-------MIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVILSLVSTRQEENPSTSLDSNGAALPD--GNIAESLESLV-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAH5-1", "uniprot_id": "A0A8M2BAH5_DANRE", "id": "A0A8M2BAH5-1", "name": "protein-tyrosine-phosphatase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MEALATRCAFFLAQIALFS-------------------NTGLSEAYG-YRSQKKLSENVEWSYAGTLNQNNWAKKYPSCNNAKQSPINVEESLAQVKIQFQKLRLEGWLEKTSD----------STTVKNDGKTVAIDVGGEFYVSGGGLRSKFKVGRISFHWG-------------------LCNASSDGSEHGLNGEKYPLEMQIYCYEADVFSDLDEAFREGG----------KITALAVLFETSTEDNVNYTAIIDAVNSVSRYGKSGSISPFTMQGLLPSSTEKYFIYNGSLTTPPCSETVEWIVFKNTVAISDVQLEMFCEVMTMQQVGYVMLMDYLQNNYRNQQEQFMGQVFSSYT--------------GVEEVHTPICSSEPENVQASPHNYTSMLVIWERPRAVYDSSIERYSVTYRPAQGDDESALEYLTDGDQDVGAIIQDLVANTSYMVQVVAVCTNGLYGRVSDQLTVDVPLDDPEADNDSESF-----------DYDEEENYHINPFLIRPETERLPYPFQTTTTSPRVTTTERLIHPVVKTTQRTHERRLPVEESQKTHDDIFPVVYTDKPTAKHTDQPTTITTTFVVDVHTTTPDSFR-------------------------------------------------------------------------------------------FIAGVSSESDVQSSSFTDSPTSVTPETSETLER-FVTSASIDILEVEDVTEPVTITDSFEESS------QTVAPLLE----------------------------------IPVDSTSSTFPSEVPLRP---------------------------TAASLPFPTTAAFSTVLSQTTQPVFNGES-----------------------APYAPSVSDTLSYVHASPVSP---YSLSSVLSEPIPDWDIPYTVTML----------VSGGAQSITPSPSYPTLSLSGSVSYLD-------------------------------------MESVSSGGCIDDDGDDAVLSGSASADPPCRTT-----------------LPLQTLSEVTASVDLMQPSSEPSLLHLSEHSGTISVLSTPAYLQ----------------------------PSVPVSKDYSETTTTLDTDASLSGSNGESNLLTEWVDSSLAAPTFSSK-------------------------------------------------------FSLHASSNSLLPSSVSGLPPCSSLLSSPV--------------ELHLFQSTSSASTSLCSDAGLDLSTKALLPSLSISTKPSSDLSLSVAATVNNIAQSAIGQSLGASAPIRSSAITPTPILELRS------------------------------TPTPVVPPTIA----------------------------------------------------------------PTSPSDSITVVAPVVPP-------------------TIPVSSAPESSSMPTHSADGQQENSASG----------------------------WTFDLDWGQSSASGDESIAAPYITTASPTEVSPEETDDGNEEHSSSFY---------------------------FEGENGTESEVTDFRVTLQPSPSWTLRGSGEEESGSGETLTDNETSSDFSIPERTER-------------------------------------------------------------------------------------------------------------------------------------ESEEEPVEDANNSSHESRVGLASSIERQKKAVVPLAVVSTLTFLGLIFLIGIYIYWR-----------------------------KCFQTAHFYIEDSTSPRVISS--SPLLNPTG-----------------EHEPLPVKQFVNHVTELHNTSSFSREFEILKEYFEEVQTCTVDLGTTTDCSNHPDNKNKNRYVNILAY------------------------------------DHSRVRLAPLNDKDGKSGGDYINANYVD------GFNKNKAYIAAQGPLKSSTPDFWRMVWEQNVGVIVMITNLVEKGRK--------------------KCDQYWPLE--NQEEYGCFLVTVKSTNVLAYYTKRTFTLRNTSIKKGSQR---YRSNERTVTQYHYTQWPDMGVPEYVLPVLSFVYKSSKAQTDG--MGPMVVHCSAGVGRTGTYIVLDSMLKQIKEKGTVNIMGFLKHIRTQRNYLVQTEEQYIFTHDALVEAILSQETEVSSSHIHQYVNNLLTPGA--SCK-TRLEKQFKLVCQSNAKQ--NDCSAALSDCNRTKNRNCSLIPVEKSRVCVSSSAGET--------------------SDYINASYVMGYRQNKEFIITQNPLPNTVKDLWRMVWDQNSQVIVSLPDRSSTTEDSEPVIFWPTRDQPIIYETFSVSLRGEDHVCLSNEDMLIVQDYILEATKDDFVLEVKHFRSPRWPNPDSPISSVFEMIRIIQKEAS------SKDGP-------MVIHDEHGGVTAGTFCALFTLLQQLEAESVVDVYMVAKMINLMRPGVFTDIDQYQFLYKAILSLVSTQEDEQALQSSDNNGTVPGDV-SSATESLESLV-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J953-1", "uniprot_id": "A0AC58J953_DANRE", "id": "A0AC58J953-1", "name": "protein-tyrosine-phosphatase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MRPITAKPHLFIAQLWLIW-------------------HSDLAASY--LRGQRKFTEDVDWSYTGALNQKHWVKKYPVCGNARQSPIDISEEFTQVRLQYQNLQLENWEQPTTD----------STTITNDGKTVVIGLNSEYFISGGGLRSRFKVGRITFHWG-------------------RCNATSDGSEHSLNGNRFPLEMQIYCFDDLEFESIDEAMSSGG----------KIAAVAVLFQASIEDNQDYAAIIEGVNNVSRFGKSSAVEEFSLLALLPENTEKYFMYNGSLTAPPCSENVEWIVFKNTVGISETQLEVFCEVMTMQQAGYAMLTDYLQNNYREQQQQFMGQVFSSYT--------------GTEEVPAPMCSSEPQNVQADSQNFTGIVVTWERPRAVYDTVIERYSVTYQRLQGQNPPKQQYLTDGDQDVGAIIHNLLANSSYVVQVVALCMNGLTGKMSDQVIVDMPFEDPVNEPD---------------------------------------PYGDLAES-------------------------------------------EEYNEEHTSAPS------------SKPPPGR-------------------------------------------------------------------------------------------FLIRDSG-SSISITTSTDQPGFLFPVS---------------------RTTPITVRRKITEES------SLSQPPVQ----------------------------------NKSRKNETKRPANRLLPD---------------------------DSGHFPQSN----TVVTDVYYEDVLNSST-----------------------TNITPTINNNL----------------------------------------------------------------------------------------------------------------------LIDQN------TEKASTSPPK------------------------------------QPANES-------------------------------------------------------------STANATTGSSLSAS--------------------------------------------------------------------------------------------------------------------------------------------------------MKIISQTTQPLFNDVFVTATSFNNERVLMVSDATSLYESSTRSPTIILEEGS------------------------------AHFPPS---------------------------------------------------------------------------------------------------------------------------DGQGEFSGSG----------------------------SAIFLEELDREWELEQTRMAP--KNADPRKTQ----EENHEGLPSTFF---------------------------FESEREASSTYKPQNQDFLSWVTWSAESDSGSGQGGSMISQTEDIPIQLIIPKLN----------------------------------------------------------------------------------------------------------------------------------------IQEENHAEASNSSPESRVGMVGGTETEKRAVVPLAIVSTLTVLCLVVLVGILIYWR-----------------------------RCFQTAHFYVEDTNSARAISAPSTPLLLPTE-----------------DNEALPVKDFVKHVADLHANHKFSKEFEILKESYEEIQGCTADMGITTDSSNHPDNKSKNRYINILAY------------------------------------DHSRVKLSQNSDKDGKTG-DYINANYVD------GFNQPKAYIAAQGPLKGSLEDFWRMIWEQNVGVIVMITNLVEKGRR--------------------KCDQYWPLE--NQEDYGCFLVTLKSSRTLAYYTLRTFTLRNVQIKKGSQK---GRSQERTVLHFHYTQWPDMGVPEYTLPLLSFIRTSSQARTAE--MGPVVVHCSAGVGRTGTYIVIDSMLKQIKEENTVNIMGFLKHIRTQRNYLVQTEEQYVFIHDALVEAIRSKETLVSSSLIHTYVSGLLTPGP--AGK-TPLEKQFKLVSQSCAKQ--SDYTTALKESNVSKNRTACLMPVERSRVSLSAAAGES--------------------SDYINASYLLGFHQSREFIVTQNPLPNTIHDFWRMIWDHNTQIIVSLPDTHNMSSEAE-CVYWPTKDEPISCETFTVSFRDEDSLNLSNEEPVLVQHFILEALKDDYVLEVHQFQSPRWPDPDSPISNCFELINIIREESS------RREGP-------VLIHDGCGGSSAGLFCALVTLVNQLDEENSVDVYQTARMINLMRPGVFNDVEQYQFLYKAILSLVSTQEDERALQYAENNGTVP----ANPSESLESLM-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9Q0N2-1", "uniprot_id": "PTPRH_MOUSE", "id": "E9Q0N2-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARAGGNCGVWRSLVLLGLYGCSVVRAAG-----------------------------------------------------TSVTVDRHAPASSYEFSMWVEKDGVSSS-PQIPVTTAAPNP-----------------------VRNLRVEGQNNISISLSWEPPDQSS---------------------------------------------------------------------LQGLTYWTQCSRHGGQTETRNTTDTSVTVDGLDPGSSYECSVWVEKD-GLYSKNETLNTSTAPNPVRNLRVEGQNNISISLSWE-------------PPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTT-------------------------------------------------------------------------------DTSITVDGLDPGSSYECSVWVE-KDGVY----------------------------------------------------------------------------------------------------------STNETLSNTTAPNPVRNLRVKSQNNFSISLSWEPPDQPSLQGLIYWAQCSRHGGQTETRNTTDTS---------------------------------------VTVDGLDPGFLYKCSVWVEKDG-----------------------------VYSTNETLNTSTVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISASNPVRNLRVEGQNN-FSISLSWEPPD-----------QSSLQ-----------------------------------------------------------------------------------------------------------------GLTYWAQCSRHGG-----------QTETRNTADTSVTVD---GLDPGSSYECSVWVEKD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVYSTNETLNTSTVPAAVNITSCISTSGG----YGVLLTWSCP---------------------------------SGGYESFEVKVGRKWRSE------------NGSLCGKGVTVSDLEP---------------------------------------------------------------------------------------------------------------------------------AQSYTATVTTVFKDLKAQSLS-----------------TTCHTESAAIIAGAIVGILL--------------------------------LFILVGLLIVFLKRRRKKR-QPKEVPKDLVC----------------SCPGDILAKDFADHVRENEKDSNCG-----FAEEYQQLALEG--QGQSQITASALENRSKNRYRNVLPY------------------------------------DWSRVPLQPLQ---EEPGSDYINASFMP------GLWSPKEFIATQGPLPNTVGDFWRMVWEQQSHTLVMLTNCMESGRV--------------------KCEHYWPLDA-QPCIHGQLQVMLISEEASENWTVRHLQLFHMKEQQ-----------TLSLRQFHYLAWPDHGVPYSPDPLLAFRKMLRQWMDQTTDGGPPIVHCSAGVGRTGTLIALDVLLRQLECEGLVGPFSFVKKMRESRPLMVQTEAQYVFLHQCILKSLQKPAPALV------PEEAMYENVA--SLVYENASAIMAHESEFSASGC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD43-1", "uniprot_id": "PTPRH_HUMAN", "id": "Q9HD43-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAGGGLGVWGNLVLLGLCSWTGARAPAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTT-ATNVTVDGLGPGSLYTCSVWVEKDGVNSS-VGTVTTATAPNP-----------------------VRNLRVEAQTNSSIALTWEVPDGPD---------------------------------------------------------------------PQNSTYGVEYTGDGGRAGTRSTAHTNITVDGLEPGCLYAFSMWVGKN-GINSSRETRNATTAHNPVRNLRVEAQTTSSISLSWE-------------VPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSVEIVTSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTA-------------------------------------------------------------------------------HTNITVDRLEPGCLYVFSVWVG-KNGIN----------------------------------------------------------------------------------------------------------SSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTS---------------------------------------VTAERLEPGTLYTFSVWAEKNG-----------------------------ARGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSG-------------------------------------------------------------------------------------------------------TDITLKELEAGSLYHLTVWAERNEVRGY-----------------------------------------------------------------------------------------------------NSTLTAATAPNEVTDLQNETQTK-NSVMLWWKAPG-----------DPHSQ-----------------------------------------------------------------------------------------------------------------LYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKVE---ALEPGTLYNFTVWAERN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVASSTQSLCASTYPDTVTITSCVSTSAG----YGVNLIWSCP---------------------------------QGGYEAFELEVGGQRGSQ------------DRSSCGEAVSVLGLGP---------------------------------------------------------------------------------------------------------------------------------ARSYPATITTIWDGMKVVSHS-----------------VVCHTESAGVIAGAFVGILL--------------------------------FLILVGLLIFFLKRRNKKK-QQKPELRDLVF----------------SSPGDIPAEDFADHVRKNERDSNCG-----FADEYQQLSLVG--HSQSQMVASASENNAKNRYRNVLPY------------------------------------DWSRVPLKPIH---EEPGSDYINASFMP------GLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRV--------------------KCEHYWPLDS-QPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQK-----------TLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQSAQAPA------EKEVPYEDVE--NLIYENVAAIQAHKLEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64455-1", "uniprot_id": "PTPRJ_MOUSE", "id": "Q64455-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPAARETRTPPRSPGLRWALLPLLLLLRQGQVLCAGAAPNPIFDIEAV-VSPTSVLLTWKHNDSGASECRIEN--KMESNLTFPVKN-QTSCNITGLSPGTSYTFSIISVTTNETLN----KTITTEPWP-----------------------VSDLHVTSVGVTQARLTWSNANGTASYRMLIE------ELTTHS--SVNISGLKPGTNNSFA--FPESNETQADFAVAEEVP-DANGTKRIPVTNLSQLHKNSLVS-VDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWK-------------SNYDGSRTSIVYKIHVAG-GTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIK----QDGGEKHRNASTG-------------------------------------------------------------------------------NQSYMVEDLKPGTSYHFEIIPRGPDGTE----------------------------------------------------------------------------------------------------------GLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQNTDD--ASGYTYHLVLESKSGSIIRTNSSQKW---------------------------------------ITVGSLTPGTLYNVTIFPEVDQ-----------------------------IQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKD--------------------------------------------------------------------------------------------------------PSILIPELIPGVSYTVKILTQVGDGTTS---------------------------------------------------------------------------------------------------LVPGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGFELGVRSDSWD-----------------------------------------------------------------------------------------------------------------NMTRLENCTSDDDTECRTEVAYLNFSTSYNISIATLSCG---KMALPAQNICTTGITDP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAAQ--------------PSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEP---------------------------------------------------------------------------------------------------------------------------------LGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGAL-----------------------------AITAVGGFIFWRKKRTDAK-NNEVSFSQIKP----------------KKSKLIRVENFEAYFKKQQADSNCG-----FAEEYEDLKLIG--ISLPKYTAEIAENRGKNRYNNVLPY------------------------------------DISRVKLS-VQ---THSTDDYINANYMP------GYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRT--------------------KCEEYWPSK--QAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNSE-----------SHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRA-QKDSK------VDLIYQNTTA--MTIYENLEPVSMFGKTNGYIA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JXZ9-1", "uniprot_id": "A0A0G2JXZ9_RAT", "id": "A0A0G2JXZ9-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "-----------------------------------------------------------------MTRGGGRGSSRGRGSPELDATRGGWAPLAPPREAPACLGPRPLRVRSARLR-RVAAAAAAAMSPGKPGAGGAGTRRTGWRRRRRRRRLEAETRAPGFGHTAGRVPGTFQGAQGMKPAARETRTPPRSPGLRWALLPLLLLLRQGQVVCAGAAPSPVFDVEAV-TSPTSVVLTWKHNDSATSEYKIN----EGNTLRYTVKN-QTSFNITGLSPATSYKFSITLGTVNETSGKPTYKNITTEPWP-----------------------VSDLQVAYIGVTQALLAWSNANGTASYRMQIV------ELTTNS--SGGISDLKPGTHKSLA--VQGSNETQHDLWVTEGVSADANGTEGSPVANISQLHKNSLAS-ADPPSARDPSLTEVLLTELKPDTQYKVTIYSQAADGTEGQPGNKVFKTNPIQVSDIRAVNISDSNMTLTWK-------------SNNNESHASFTYKIYVAG-GSDSINETVNETQAVIRGLSSSTLYNITVLPFLGQTAGIPGFLQVYTSPRPVSDFRVTNVSLREIGLAWRSNDSESFEIFIT----QEGSEKRWNASTG-------------------------------------------------------------------------------DLSYIVENLKPGTSYQFEIFPRGPNGTE----------------------------------------------------------------------------------------------------------GPSQTVVGRTDCSAVTDIRVVSVSTTEIQLEWQNTDS--ASGYTYHLVLESENGS-IKTNSSQKW---------------------------------------ITVGGLTPGTLYNVTIFPEVDQ-----------------------------MEGNSSSITQYTRPSNVSYIEVNTNTTVAAIQWKNLDAASASYSYSVLILKAGDGSNVTSRVRDI--------------------------------------------------------------------------------------------------------PSVTIPGLIPGVSYEVKIFTKIRNTEVGN--------------------------------------------------------------------------------------------------EVPGQKLFCMEPAQVDSLHCEVVPKEPALVLKWACPPGMNSGFELGVRSDAWD-----------------------------------------------------------------------------------------------------------------NMTHLENCTLDNDTECRTEVTYLNFSTSYNISIATLSCG---KMALPTQSTCTTGITDP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVLLTTGEAGQ--------------PSTDVLKYTYEDFKKGASDTYVTYLIRIEEKGQSQGLSEALNYEIDVGNQSTTLGYYNGRLEP---------------------------------------------------------------------------------------------------------------------------------LGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVSLPQDPGVICGAVFGCIFGAL-----------------------------AIVAVGGFIFWRKKRKDAK-NNEVSFSQIKP----------------KKSKLIRVENFEAYFKKQQADSNCG-----FAEEYEDLKLIG--ISLPKYAAEIAENRGKNRYNNVLPY------------------------------------DISRVKLS-VQ---THSTDDYINANYMP------GYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRT--------------------KCEEYWPSK--QAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQSSE-----------SHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRA-QKDSK------VDLIYQNTTA--MTIYENLEPVSMFGKTNGYIA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12913-1", "uniprot_id": "PTPRJ_HUMAN", "id": "Q12913-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "-------------------------------------------------------------------------------------MKPAAREARLPPRSPGLRWALPLLLLLLRLG-QILCAGGTPSPIPDPSVATVATGENG--------ITQISSTAESFHKQNGTG-----TPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVH-QPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIP-----------------------VSDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK-------------VSDNESSSNYTYKIHVAG-ETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHIT----QEGAGNSRVEITT-------------------------------------------------------------------------------NQSIIIGGLFPGTKYCFEIVPKGPNGTE----------------------------------------------------------------------------------------------------------GASRTVCNRTVPSAVFDIHVVYVTTTEMWLDWKSPDG--ASEYVYHLVIESKHGS-NHTSTYDKA---------------------------------------ITLQGLIPGTLYNITISPEVDH-----------------------------VWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNATQVVTDIGI------------------------------------------------------------------------------------------------------TDATVTELIPGSSYTVEIFAQVGDGIKS---------------------------------------------------------------------------------------------------LEPGRKSFCTDPASMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSSGAWN-----------------------------------------------------------------------------------------------------------------NATHLESCSSENGTEYRTEVTYLNFSTSYNISITTVSCG---KMAAPTRNTCTTGITDP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAGH--------------PSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEIDVGNESTTLGYYNGKLEP---------------------------------------------------------------------------------------------------------------------------------LGSYRACVAGFTNITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDPGVICGAVFGCIFGAL-----------------------------VIVTVGGFIFWRKKRKDAK-NNEVSFSQIKP----------------KKSKLIRVENFEAYFKKQQADSNCG-----FAEEYEDLKLVG--ISQPKYAAELAENRGKNRYNNVLPY------------------------------------DISRVKLS-VQ---THSTDDYINANYMP------GYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRT--------------------KCEEYWPSK--QAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSE-----------SHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRS-QKDSK------VDLIYQNTTA--MTIYENLAPVTTFGKTNGYIA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70289-1", "uniprot_id": "PTPRV_MOUSE", "id": "P70289-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "MRPLILLAALLWLQDSLAQEDVCSSLDGSPDRQGGGPPLSVSVTSRGRPTSLFLSWVAAEPGGFDYALCLRAMNLSGFPEGQQLQAHTNESSFEFHGLVPGSRYQLELTVLRPCWQNVTITLTARTAPTVVRGLQLHSTGSPASLEASWSDASGDQDSYQLLLYHPESHTLACNVSVSPDTLSYNFGDLLPGSQYVLEVITWAGSLHAKTSILQWTEPVPPDHLRVRALGTSSLQAFWNSSEGATWFHLILTDLLEGTNLTKVVRQGISTHTFLRLSPGTPYQLKICAAAGPHQIWGPNATEWTYPSYPSDLVLTPLW-----------NELWASWKAGQGARDGYVLKLSGPVENTTTLGPEECNAVFPGPLPPGHYTLGLRVLAGPYDAWVEGSIWLAESAARPMEVPGARLWLEGLEATKQPGRRALLYSVDAPGLLGNISVSSG-ATHVTFCGLVPGAHYRVDIASSMG-DITQSLTGYTSPLPPQSLEIISRNSPSDLTIGWAPA-------------PGQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLTLKSLVPGSCYTVSAWAWSGNLSSDSQKIHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGRDAFQLRLYRLRPLTLESEKILS-------------------------------------------------------------------------------QEAQNFSWAQLPAGYEFQVQLSTLWGSEE---------------------------------------------------------------------------------------------------------SGSANTTGWTPPSAPTLVNVTSEAPTQLHVSWVHAAGD-RSSYQVTLYQESTRTATSIVGPKADS---------------------------------------TSFWGLTPGTKYKVEAISWAGP-----------------------------LYTAAANVSAWTYPLTPNELLASMQAGSAVVNLAWPSGPLGRGTCHAQLSDAGHLSWEQPLSLGQD--------------------------------------------------------------------------------------------------------LLMLRNLIPGHTVSLSVKCRAGPLQAS-----------------------------------------------------------------------------------------------------THPLVLSVEPGPVEDVFCQ--PEATYLSLNWTMPTGDVAVCLVEVEQLVPG-----------------------------------------------------------------------------------------------------------------GSAHFVFQVNTSEDALLLPN--LTPTTSYRLSLTVLGGNRQWSRAVTLVCTTSAEVWHP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PELAEAPQVELGTGMGVTVTRGMFGKDDGQIQWYGIIATINMTLAQ-------------PSQEAINHTWYDHYYRGHDSYLALLFPNPFYPEPWAVPRSWTVPVGTEDCDNTQEICNGHLKP---------------------------------------------------------------------------------------------------------------------------------GFQYRFSIAAFSRLSSPETILAFSAFSE------PQASISLVAMPLTVMMGTVVGCIIIVC-----------------------------AVLCLLCRRGLKGPRSEKNGFSQELMPYNLW----------------RTHRPIPSHSFRQSYEAKSARAHQA-----FFQEFEELKEVG--KDQPRLEAEHPANITKNRYPHVLPY------------------------------------DHSRVRLTQLS---GEPHSDYINANFIP------GYSHPQEIIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMENGRV--------------------LCEHYWPVNS-TPVTHGHITTHLLAEESEDEWTRREFQLQHGAEQK-----------QRRVKQLQFTTWPDHSVPEAPSSLLAFVELVQEEVKATQGKGPILVHCSAGVGRTGTFVALLPAVRQLEEEQVVDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPSDASDSGPIPVMNFAQACAK--RAANANAGFLKEYRLLKQAIKDETGSLLPSPDYNQNSIASCHHSQEQLALVEESPADNMLAAS--------------------------LFPGGPSGRDHVVLTGSAGPKELWEMVWEHGAYVLVSLG--------LPDTKEKPQDIWPMEMQPIVTDMVTVHRVAESN-TAGWPSTLIRVIHGDSGTERQVQCLQFPHCETGSELPANTLLTFLDAVGQCCSRGNSKKPGT-------LLSHSSKVTNQLSTFLAMEQLLQQAGTERTVDVFSVALKQTQACAVKTPTLEQYIYLYNCLNSALRNRLPRARK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64612-1", "uniprot_id": "PTPRV_RAT", "id": "Q64612-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "MRPLILLAALLWLQGFLAEDDACSSLEGSPDRQGGGPLLSVNVSSHGKSTSLFLSWVAAELGGFDYALSLRSVNSSGSPEGQQLQAHTNESGFEFHGLVPGSRYQLKLTVLRPCWQNVTITLTARTAPTVVRGLQLHSAGSPARLEASWSDAPGDQDSYQLLLYHLESQTLACNVSVSPDTLSYSFGDLLPGTQYVLEVITWAGSLHAKTSILQWTEPVPPDHLALRALGTSSLQAFWNSSEGATSFHLMLTDLLGGTNTTAVIRQGVSTHTFLHLSPGTPHELKICASAGPHQIWGPSATEWTYPSYPSDLVLTPLR-----------NELWASWKAGLGARDGYVLKLSGPMESTSTLGPEECNAVFPGPLPPGHYTLQLKVLAGPYDAWVEGSTWLAESAALPREVPGARLWLDGLEASKQPGRRALLYSDDAPGSLGNISVPSG-ATHVIFCGLVPGAHYRVDIASSTG-DISQSISGYTSPLPPQSLEVISRSSPSDLTIAWGPA-------------PGQLEGYKVTWHQDGSQRSPGDLVDLGPDTLSLTLKSLVPGSCYTVSAWAWAGNLDSDSQKIHSCTRPAPPTNLSLGFAHQPAALKASWYHPPGGRDAFHLRLYRLRPLTLESEKVLP-------------------------------------------------------------------------------REAQNFSWAQLTAGCEFQVQLSTLWGSER---------------------------------------------------------------------------------------------------------SSSANATGWTPPSAPTLVNVTSDAPTQLQVSWAHVPGG-RSRYQVTLYQESTRTATSIMGPKEDG---------------------------------------TSFLGLTPGTKYKVEVISWAGP-----------------------------LYTAAANVSAWTYPLIPNELLVSMQAGSAVVNLAWPSGPLGQGACHAQLSDAGHLSWEQPLKLGQE--------------------------------------------------------------------------------------------------------LFMLRDLTPGHTISMSVRCRAGPLQAS-----------------------------------------------------------------------------------------------------THLVVLSVEPGPVEDVLCH--PEATYLALNWTMPAGDVDVCLVVVERLVPG-----------------------------------------------------------------------------------------------------------------GGTHFVFQVNTSGDALLLPN--LMPTTSYRLSLTVLGRNSRWSRAVSLVCSTSAEAWHP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PELAEPPQVELGTGMGVTVMRGMFGKDDGQIQWYGIIATINMTLAQ-------------PSREAINYTWYDHYYRGCESFLALLFPNPFYPEPWAGPRSWTVPVGTEDCDNTQEICNGRLKS---------------------------------------------------------------------------------------------------------------------------------GFQYRFSVVAFSRLNTPETILAFSAFSE------PRASISLAIIPLTVMLGAVVGSIVIVC-----------------------------AVLCLLRWRCLKGPRSEKDGFSKELMPYNLW----------------RTHRPIPIHSFRQSYEAKSAHAHQT-----FFQEFEELKEVG--KDQPRLEAEHPDNIIKNRYPHVLPY------------------------------------DHSRVRLTQLP---GEPHSDYINANFIP------GYSHTQEIIATQGPLKKTLEDFWRLVWEQQVHVIIMLTVGMENGRV--------------------LCEHYWPANS-TPVTHGHITIHLLAEEPEDEWTRREFQLQHGTEQK-----------QRRVKQLQFTTWPDHSVPEAPSSLLAFVELVQEQVQATQGKGPILVHCSAGVGRTGTFVALLRLLRQLEEEKVADVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPPDSSDSGPISVMDFAQACAK--RAANANAGFLKEYKLLKQAIKDGTGSLLPPPDYNQNSIVSRRHSQEQFALVEECPEDSMLEAS--------------------------LFPGGPSGCDHVVLTGSAGPKELWEMVWEHDAHVLVSLG--------LPDTKEKPPDIWPVEMQPIVTDMVTVHRVSESNTTTGWPSTLFRVIHGESGKERQVQCLQFPCSESGCELPANTLLTFLDAVGQCCFRGKSKKPGT-------LLSHSSKNTNQLGTFLAMEQLLQQAGTERTVDVFNVALKQSQACGLMTPTLEQYIYLYNCLNSALLNGLPRAGKWPAPC---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35832-1", "uniprot_id": "PTP99_DROME", "id": "P35832-1", "name": "Tyrosine-protein phosphatase 99A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPQHHALLRAMLKLLLFASIAEHCATALPTNSSNSPSSPSPFTAASLPPTTASSSSSPAVISTSSSD-----------------RNLADLVNPEAETTGSGWESLETEFNLATTVDSS---------------------TQKTEKEPVLGTVATSIEQQDQPPDVPATTLAFAN-------------------AFPVPVAGEMGNGNGNYNDATPPYAAVDDNYVPSKPQNLTILDVSANSITMSWHPPKNQNGAIAGYHVFHIHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYRVIVKAFTTKNEGEPSDQIAQR-----------------TDVGGPSAPAIVNLTCHSQESITIRWRRPYEFYNTIDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTNSYYEVKVAAATFSVINPKKIVLGKFSESR----------------------------------------------------------------------------------------------IIQLQPNCEKLQPLLRQSHNDYN---------------------------------------------------------------------------------------------------------LAVLVGIIFSCFGIILIIMAFFLWSRKCFHAAYYYLDDPPHHPNAPQVDWEVPVKIGDEIR------------------------------------------------AAVPVNEFAKHVASLHADG----------------------------DIGFSREYEAIQNECISDDLPCEHSQHPE----------------------------------------------------------------------------------------------------------------------------------------------------NKRKNRYLNITAYDHSRVHLHPTPGQ---------------------------------------------------------------------------------------------------KKNLDYINANFIDGYQKG-------------------------------------------------------------------------------------------------------------------------------------------------------------HAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIK---------------------------------------------HLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLN-------------------------------------------------------------------------------------------------------------------------------------FVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVN-------------------------------------------VFGFLRHIRAQRNFLVQTEEQYIFLHD----------------ALVEAIASGETNLMAEQVEELKNCTP---YLEQQYKNIIQFQP-KDIHIASAMKQVNSIKNRGAIFPIE-------------------------------------GSRVHLTPKP---GEDGSDYINASWLH------GFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDIN-----------------------FAQFWPDEA-TPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDY-----------ELTVKMLHCPSWPEMSNPN---SIYDFIVDVHERCNDYR-NGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYN-ILSFLPGNLNLLKRTALRTEFEDVTTATPDLYSKICSNGNVPQHVILQQQQLHMLQLQQQHLETQQQQQQQQQQQQQQQQQTALNETVSTP--------------------STDTNPSLLPILSLLPPTVAPLSSSSSTTPPPPSTPTPQPPQTIQLSSHSPSDLSHQISSTVANAGSPATASAGATPTTPMTPTVPPTIPTIPSLASQN------SLTLTNANFHTVTNNAADLMEHQQQQMLALMQQQTQ--------------------LQQQYNTHPQQHHNNVGDLLMNNADNSPTASPTITNNNHITNNNVTSAAATDAQNLDIVG--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------SPVLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELGKIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDN----------------LTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKSPKTNLMNSLHNTAP---------------------------------------------------------------------------------------------HMTATTPLSSPQMNLKLKVPDDSR---------------------------------------------------------------------------------------------------------SDHSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAP-----------------------------------------------------------------------QTNINQMFKFSQNEEIMG--------------------------------LETYLSAVNIKEEHERWYNNDSAKKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNFQFPKNQNSLEKDTNK------------------------------------------------------------------------------------------------------------------------------------------------------------------DKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIELVSQFQKLDFLEKRRLNHSVSFRKKENS------------------------------------------------FILEKPSSYPEQLTSTSSSTIMPPKFPDVNKVQKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHSQPIFTQYSKYKSMLS------------------LESDSDSESDDVIISSGVELGAKN----RYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDN-------------------------------------YINANYLSLPRFSVEQNSSFQTTTTTT---------RRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIE--------------------KCYRYWQEG-----NYNGIHVKLLEKKILKMPSTTSMRKNTMGTQN---------------SSLYSAGVQGNSSNYSTDNDNDNDNNNNNNNNSN--IAVTAAACDDDDDDDDDAILIRKILLTYHDQE--KPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCS----AGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTIN--------------------------------------------------IFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITER------------------------------------------------------------------------------------------------------------TDGDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ--------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : . . *.:* . **: : . :: :: : .:* : . . . : . : . : ", "identical_positions": 5, "similar_positions": 29, "identity": "0.17%" }, { "cls_id": "homologset.agr.SGD:S000000880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B7ZMP1-1", "uniprot_id": "XPP3_MOUSE", "id": "B7ZMP1-1", "name": "Xaa-Pro aminopeptidase 3", "aln": "------------MPSLLSTPKLAPVLARLRGLSGCMSCLQRRYSLQPAP----------VKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQ-------GHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSFSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDEAYPLEEFQHLLPKLRAETN-MVWYDWMKPS-HAQLHSDYMQPLTEAKARSK--------NKVRSVQQLIQRLRLVKSPSEIKRMQIAGKLTSEAFIETMFASKAPIDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLTLCSPG------TSLENIYSMMLTLIGQKLKDLGITKT--SKES-AFKAARKYCP-HHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEDDRDAPEKFRGLGVRIEDDVVVTQD-SPLILSADCPKEMNDIEQICSRTS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEQ3-1", "uniprot_id": "XPP3_RAT", "id": "B5DEQ3-1", "name": "Xaa-Pro aminopeptidase 3", "aln": "------------MLSLLSTPRLVPVIARLRGLSGCMSCLQRRYSLQPVP----------VKEIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQ-------GHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETN-MVWYDWMKPS-HAQLHSDYMQPLTEAKATSK--------NKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPG------TSLENIYSMMLTLMGQKLKDLGIIKT--SKES-AFKAARKYCP-HHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQD-SPLILSADCPKEVNDIEQICSRTS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQH7-1", "uniprot_id": "XPP3_HUMAN", "id": "Q9NQH7-1", "name": "Xaa-Pro aminopeptidase 3", "aln": "------------MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVP----------ERRIPNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQ-------GQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVDEAYTLEEFQHLLPKMKAETN-MVWYDWMRPS-HAQLHSDYMQPLTEAKAKSK--------NKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPG------TSLENIYSMMLTLIGQKLKDLGIMKN--IKENNAFKAARKYCP-HHVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQD-SPLILSADCPKEMNDIEQICSQAS----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40051-1", "uniprot_id": "ICP55_YEAST", "id": "P40051-1", "name": "Intermediate cleaving peptidase 55", "aln": "------------MLHRINPVRFS-MQSCQRYFSKLVSPLEQHKSNTFTN----------RVRIP-IEAGQPLHETRPFLIKSGELTPGISALEYYERRIRLAETLPPKS---------------CVILAGNDIQFASGAVFYPFQQENDLFYLSGWNEPNSVMILEKPTDS-LSDTIFHMLVPPKDAFAEKWEGFRSGVYGVQEIFNADESASINDLSKYLPKIINRND-FIYFDMLSTSNPSSSNFKHIKSLLDGSGNSNRSLNSIANKTIKPISKRIAEFRKIKSPQELRIMRRAGQISGRSFNQAFAKRFR--NERTLDSFLHYKFISGGCDKDAYIPVVATGSNSLCIHYTRNDDVMFDDEMVLVDAAGSLGGYCADISRTWPNSGKFTDAQRDLYEAVLNVQRDCIKLCKASN----NYSLHDIHEKSITLMKQELKNLGIDKV--SGWN-----VEKLYP-HYIGHNLGLDVHDVPKVSRYEPLKVGQVITIEPGLYIPNEES-FPSYFRNVGIRIEDDIAIGED-TYTNLTVEAVKEIDDLENVMQNGLSTKFEEDQVAPL----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W5W7-1", "uniprot_id": "Q9W5W7_DROME", "id": "Q9W5W7-1", "name": "Aminopeptidase P N-terminal domain-containing protein", "aln": "-MNILRRLDRLIAPTVRRSAAISTSLWPHRWMSQSTTISPGSPSSKSTVNAAEVRGVAQILRQQKGNLGQPTSVSHPHLIQPDELVPGVELTEIKERRSQLMQNIRAYARSFGGEFNGHSSSCHMLVLGAASKKYMSGKIPYVFRQNSDFYYLTGCLEPDAVLLLT---IDEAQNVQSELFMRPKDPHAELWDGPRTGPELAVPLFGVTEAHPLSQLEAVLAKRAGALKPHIWFDQKSTDLPSLAEN-----MLRLSGNQQ--------RPLLPAYTFLEAMRLLKSRDEMQLMRRTCDIASRSFNEVMAETRPGQSEHHLFAAIDYKCRMRNASYLAYPPVVAAGKNATVIHYVANSQLLGQQDLVLMDAGCEYGGYTSDITRTWPASGVFTEPQRTLYDMLHQLQEEIIGNVMKPG----GETLDQLFETTCYKLGKYLQEIGLVGKSFSEYKELVSQGYRFCP-HHVSHYLGMDVHDTPHVPRNTRIVPGMVFTVEPGIYIGQDCGDVPPEFRGIGIRIEDDLLINENGHVEVLTEACVKDPRALQELCKQQQKNPGASSAEAF-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPS7-1", "uniprot_id": "Q8IPS7_DROME", "id": "Q8IPS7-1", "name": "Aminopeptidase P N-terminal domain-containing protein", "aln": "MLRFLRNFKYYAWQEVRRGCSVVAPPDRSDVLLVLPTVWPSELTKRIRPLSVPDLIEKFSCDAPGGQFATMSEYLRSDPRPDGVLLPDEIDLHRKMSLDDLNSYMHAKDA------FKEPHRKNRIFSHVLVVAGADSARSYPFRQRPDFLYLCDCLRPGAALVLT----RSRKRNTGALLFLSQDVDSQLS-------TIFSHMHYVDDVLPLAMLKKSLLWLLRDHSPELWHFYDPSSPVSCIVQEVANEAKIPMGNPR---------------YILQYTRTVKTSRELRALRRANATAADSMAEVIAQHHQ--IPQELAASFDYKCRLR----HARPDVTKTSCG------------LDGNGLWQMDAGCQYGGYEGGLARCWPSSGRFTPPQKMIYGALLDMRRDLCSLIQYAGCEGAVRTPLELHAAYLILLARHLRELRVLPKGVSSAAETVELARKYNCSPVVVSHVGLGKRDTSRRLLDYPFAPGNVMSLRLSISIPDDCCQAYPEFRGILCQLGDTLHVRDDYSVDLLTAACPSEPQDIEVCLPASRTRSHRLRNDGDQSGSCDTRQLQSHGDGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. . : *. . * : :. .. * *:* .: ** . .*.: ::* ::. :* : : . : .: :. * . ::. .. : . . : * :*: *:. :: : :. :: :.: * : :.:: * *. . : : :*.. . . * ..::* ** .* ** .* :* : :::. : ::. : : *::: : : : :*:. :*.. : * *:::. .: * : **.: :: * : : :: *: . .: :: ", "identical_positions": 37, "similar_positions": 126, "identity": "6.34%" }, { "cls_id": "homologset.agr.SGD:S000000883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08651-1", "uniprot_id": "SERA_RAT", "id": "O08651-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKILISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61753-1", "uniprot_id": "SERA_MOUSE", "id": "Q61753-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEAMGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHNPGVPGEQGSGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLVFRAQPSDPGMLPTMIGLLAEAGVQLLSYQTSMVSDGEPWHVMGLSSLLPSLETWKQHVLEAFQFCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43175-1", "uniprot_id": "SERA_HUMAN", "id": "O43175-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKI8-1", "uniprot_id": "Q9VKI8_DROME", "id": "Q9VKI8-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "-----------------------------------------------------MPLNIRKVLVCDAVDKSCVELLEQHGIKVTY-KLKLPVEELCQEVKNFDAAIVRSDTKITAEVLAAGSGSLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTCILIGSLARPVVPAGQSMKEGRWDRKLYAGTELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPITTEAEAKAAGIEKMTLEEIWPLADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLDGLESGKVAGAAFDVYPEEPPKSAV----------TKALISHPKVVATPHLGASTSEAQVRVAVEVAEQFIALN----------------------------------------------------GTSPKYTS------------------------YAGVINKEA----------------------------LAHYQ----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40054-1", "uniprot_id": "SERA_YEAST", "id": "P40054-1", "name": "D-3-phosphoglycerate dehydrogenase 1", "aln": "MTSIDINNLQNTFQQAMNMSGSPGAVCTSPTQSFMNTVPQRLNAVKHPKILKPFSTGDMKILLLENVNQTAITIFEEQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKTRLTSNVLQHAKN-LVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTAR--QVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYIN--------------------------------------------------EGNSVGSVN------------------------FPEVALKSLSYD------------------------QENTVRVLYIHQNVPGVLKTVN-------DILSNHNIEKQFSDSNGEIAYLMADISSVDQSDIKDIYEQLNQTSAKISIRLLY-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*: : :: . :::: * :* * .*. *** :::: .. :** *::*::*: .. * :* *.:::*: ** :.: *:*:* .** *..**. : .*** : .:: * *:: *: ****.::* *:** ::: :: *:: : ** : . : : .*:*: .*::*:*.* * * ::. :* *.*. *:* :** ::* ::: .:::.: ****:**:..**.: *:. ::: **:*.**.*** . *:* : *.* .. . : *. : ", "identical_positions": 83, "similar_positions": 119, "identity": "13.83%" }, { "cls_id": "homologset.agr.SGD:S000000884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XQ12-1", "uniprot_id": "A0A8J8XQ12_RAT", "id": "A0A8J8XQ12-1", "name": "WD repeat-containing protein 46", "aln": "MKSRGLPEVSSQALGRLKGVLHVDRRSVVGMETAPKPGRGDPPKKDKPQAKRKKPRRYWEEEPTPSAAGASPGPPRKKARTGEPRPPRSQSARIAQKPRFSKKPPIPKNASDWKKP--QRTLSGAQDPFPGPVPAPLEVARKFCRIDKSKKLPHSKPKTQSQLEKAEAQEEEASVRAARAELLLAEEPGFLVGE-DGEDTAKILQTDIVEAVDISSAAKHFDLNLRQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVTEAVRDIHFLHSEALLAVAQNRWLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVTALNARAGRLNVMAQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVGVDSTGTYMATSGLDHQLKIFDLRG--TFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKGSP----------PSLEQPYLTHRLSG-NVHGLQFCPFEDVLGVGHSGGITSMLVPGAAEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAELICLDPRALAEVD---------VTTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEHRDKVRQSLEQQQ-KKKQDKAKP-GAHPSALDRFVR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H1-1", "uniprot_id": "WDR46_MOUSE", "id": "Q9Z0H1-1", "name": "WD repeat-containing protein 46", "aln": "------------------------------METAPKPGRGVPPKRDKPQAKRKKPRRYWEEETTPAAVATSPGPPRKKARTGESRPPRSKSAHIAQKSRFSKKPPISKTAPDWKKP--QRTLSGAQDPFPGPVPAPLEEARKFCRIDKSKTLPHSKPKTQSKLEKAEAQEEEASVRAARAELLLAEEPGFLVGE-DGEDTAKILQTDIVEAVDIASAAKHFDLNLRQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVMEAVRDIHFLHSEALLAVAQNRWLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATTSETGFLTYLDVSVGKIVTALNVRAGRLSVMAQNPYNAVIHLGHSNGTVSLWSPAVKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRG--TFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKASP----------PSLEQPYLTHRLSG-HVHGLQFCPFEDVLGVGHSGGFTSMLVPGAAEPNFDGLENNPYRSRKQRQEWEVKALLEKVPAELICLNPRALAEVD---------VVTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEHRDKVRQSLEQQQQKKKQDMAMPPGARPSALDRFVRRAREGGLQVDP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15213-1", "uniprot_id": "WDR46_HUMAN", "id": "O15213-1", "name": "WD repeat-containing protein 46", "aln": "------------------------------METAPKPGKDVPPKKDKLQTKRKKPRRYWEEETVPTTAGASPGPPRNKKNR-ELRPQRPKNAYILKKSRISKKPQVPKKPREWKNPESQRGLSGTQDPFPGPAPVPVEVVQKFCRIDKSRKLPHSKAKTRSRLEVAEAEEEETSIKAARSELLLAEEPGFLEGE-DGEDTAKICQADIVEAVDIASAAKHFDLNLRQFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRFLHSEALLAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVAALNARAGRLDVMSQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRG--TYQPLSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAG--QGKASP----------PSLEQPYLTHRLSG-PVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAELICLDPRALAEVD---------VISLEQGKKEQIERLGYDPQAKAPFQPKPKQKGRSSTASLVKRKRKVMDEEHRDKVRQSLQQQH--HKEAKAKPTGARPSALDRFVR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3K3-1", "uniprot_id": "Q9W3K3_DROME", "id": "Q9W3K3-1", "name": "BING4 C-terminal domain-containing protein", "aln": "------------------------------MTKVTPKGR---PKAKTP------YKRYFDGQ-----KDTETGDGDLKHVKVFSKNRQNFTGDFISMINKTKKPRPQKAP---AKP-----TKEELEARPKKNPIPKEILDKYSRGEQVQPKGVKTRHFKEQQTRKEVYLEYATEQAARTELLLQETAGQLQAD-EGETTAEFRQSQIAENVDIQSSAKHFNLNM-EFGPYRMRYTKNGRHLLLGGKRGHVAAFDWVTKRLHCEFNAMESVEDVQWLHVPTMYAVAQKSWVYFYDKKGTELHCIKRLNRVNRLDFLPYHFLLAAGNSAGYASWLDVSIGELVGNFNTGLGDIRMLRHNPRNGVLCIGGGRGVVSMWSPKVREPLAKLLCHSTAMSALAVEPKGQYLVTAGLDRAVKVWDIRMLVHDKPLTHFQLRLPANELDVSQRGMLALSQGTYLETYSDLLSGGGSG----------DGTRLPYIRQRCDA-FVHGLRFCPYEDVLGVSTAKGFQSLLVPGSGEPNFDAMEDNPYETSKQRREHEVHALLEKIPPELITLDPQEITGVD---------APTL-QEKIDAKRKLFHLKAPRINMKSRHKMKGRGGTAKAARNKQIVKDAKRKEFIAEVREAKKNVIKQHTADEVGAKGKAKTKAPRSVLDRFKPKPPKKQKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40055-1", "uniprot_id": "UTP7_YEAST", "id": "P40055-1", "name": "U3 small nucleolar RNA-associated protein 7", "aln": "----------------------------------------------------------------------------------MGHKKNGHRRQIKERENQNKFER-----------------------------------STYTNNAKNNHTQTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLPESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKNGTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQKKYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGWLKYHDVSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIRN--FKQLHSVESLPTPGTNVSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSHLFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDALELNPFETKKQRQEQEVRTLLNKLPADTITLDPNSIGSVDKRSSTIRLNAKDLAQTTMDANNKAKTN-SDIPDVKPDVKGKNSGLRSFLRKKTQNVIDE-RKLRVQKQLDKEKNIRKRNHQIKQGLISEDHKDVIEEALSRFG---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . .* .: . : . . : : : : : ** :: ** * * * : : * * :. *::* . **: :: * ::*.: :****::.*::.* ** : *::****::** . :* .*: *: .. :*: ****: : .:**::* *** ::: .. :*:***:*:**.: ..:*: .: *** *::* :.. * : :** *.*: :* ..*.**:*** : ***.*:*. : ::.:: .* *:.*:* *: :*::*:* : : * . .: .*: *:*. . * : : . . .. . **: : . *..* * *:**:***. *: .::***:.*.*:*.:* **:.: ***:* **::**:*:*.: * *:*. : ** . * * . : .: .:. * *. . : :..: * * :: : : : :: *. * . . ", "identical_positions": 132, "similar_positions": 183, "identity": "19.3%" }, { "cls_id": "homologset.agr.SGD:S000000889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M7W7-1", "uniprot_id": "SYPM_RAT", "id": "Q5M7W7-1", "name": "Probable proline--tRNA ligase, mitochondrial", "aln": "MEGLLTRCRTLSALATCSLRHSRCIVRKCYHCAPGRGQRLVVSRMFQPQNLREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRAVEKLVRVIDQEMQAIG-GQKINMPSLSPAELWRATGRWDLMGRELLRLKDRHGKEYCLGPTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSSEAAQETYSLVCDAYCRLFDRLGLRWMKARADVGSIGGTMSHEFQLPVDIGEDRLVVCPSCHFSANTEIVD--------------------------------------------------------------------------------------------------------------------LSQKICPDCQGP-LTETKGIEVGHTFYLGTKYSSIFNAHFTNAHGES-LLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPSLLAPYQVCIIPPKKGSKEAAATEIVE-RLYDDVTEALPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIAS-KRALEDPAHFEVWSQNTGEVVFLTKEGVMELLTGVHVV----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFI5-1", "uniprot_id": "SYPM_MOUSE", "id": "Q8CFI5-1", "name": "Probable proline--tRNA ligase, mitochondrial", "aln": "MEGLLTRCRTLSALAACSLRHCRYIIHKCYHRAPGRGQRLVLSRMFQPQNLREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRAVEKLVRVIDQEMQAIG-GQKINMPSLSPAELWRATSRWDLMGRELLRLRDRHGKEYCLGPTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSSEAAQETYGLVCDAYCRLFDRLGLQWMKARADVGSIGGTMSHEFQLPVDIGEDRLVVCPSCHFSANTEILD--------------------------------------------------------------------------------------------------------------------LSQKICPDCQGP-LTETKGIEVGHTFYLSTKYSSIFNALFTNAHGES-LLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPRLLAPYQVCVIPPKKGSKETAATEIVE-KLYDDIMEAVPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIAG-KRALEDPAHFEVWSQNTGEVVFLTKEGVMELLTGVHVV----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L3T8-1", "uniprot_id": "SYPM_HUMAN", "id": "Q7L3T8-1", "name": "Probable proline--tRNA ligase, mitochondrial", "aln": "MEGLLTRCRALPALATCSRQLSGYVPCRFHHCAPRRGRRLLLSRVFQPQNLREDRVLSLQDKSDDLTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIG-GQKVNMPSLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLPFVKVQADVGTIGGTVSHEFQLPVDIGEDRLAICPRCSFSANMETLD--------------------------------------------------------------------------------------------------------------------LSQMNCPACQGP-LTKTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKP-TLAEMGCYGLGVTRILAAAIEVLSTEDCVRWPSLLAPYQACLIPPKKGSKEQAASELIG-QLYDHITEAVPQLHGEVLLDDRTHLTIGNRLKDANKFGYPFVIIAG-KRALEDPAHFEVWCQNTGEVAFLTKDGVMDLLTPVQTV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZY9-1", "uniprot_id": "Q9VZY9_DROME", "id": "Q9VZY9-1", "name": "Probable proline--tRNA ligase, mitochondrial", "aln": "---------------------------------MNKASRIFCPALITPKNAVVKQTEQLS--------RSQKLLTELGLVKSGSNGTYQIMPMAQRSVDKCIDLVQSNMQQAG-GQKITLPILTPTGLWKKTGRLDGDISEFYMVRDRSGKQFLMSPTHEEAVTAMLATTSPISYRQLPLRLFQIGPKFRDELKTRFGLMRAKEFLMKDMYSFDVSEETAMETYTLVNAAYDRLFKQLEVPFVKVNAATGIMGGSVSHEYHYVSPVGEDNLLQCSSCGFAGNSEVVK--------------------------------------------------------------------------------------------------------------------APAS-CPSCNSSDLKEVRGVEVAHTFLLGDKYSKPLGATFLNTTGKP-QSLVMGCYGIGITRVIAAALEVLSSDHELRWPKLLAPYDVCLIGPKQGSKEQPEAEVIENELLLNVGEICG--HQELLHDDRKELTIGKRLLEAKRLGHPLTIVVGAKSARLDSPKLEVHTS-KGETYELDFSETLKLVAEHSQHKKSLERGCFQSETEESKSRSVGHQL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39965-1", "uniprot_id": "SYPM_YEAST", "id": "P39965-1", "name": "Probable proline--tRNA ligase, mitochondrial", "aln": "--------------------------------MLKYRTLSRSCHIFHPKSLSNNTLKSET---------TQELLQTVGFVRRSQVGLFQWLPLGLRSLNKVSNAIRNRMDSDGGAIEVSLSAISSKALWQATDRWNNS--ELFKLKDSKGKQYCLTATCEEDITDLMKN-YIASYKDMPITIYQMTRKYRDEIRPRGGILRGREFLMKDAYSFASNEEDAFASFQKLDDTYNKIFKDLKIPFVSAWADSGDIGGEFSKEFHLIHESGEDTLMSCKHCGDISTLDMSQSYPEKDGQYSGDVDCKYALTKDHSTLICFYYPKDRQLNWNLALNAMDKDIDLTLRNKPNDHVLQVYEKDNEDIMFSKILRVMDCRLNSKSNFPDFPLKKYLKNNFGQISDVSIVDAQENEICGKCEEGRLEPLKSIEVGHIFLLGNKYSKPLNVKFVDKENKNETFVHMGCYGIGVSRLVGAIAELGRDSNGFRWPAIMAPYKVSICTGPNNPENSQRLQDVKSELLN--DPTMQNLQNDILDQFNEKLGIGARIKLSHAMGIPLCVIVG--SKSWPNVEIEVRGIRWGEKDLWRKQFEKRCSELQWKCTKNEHGIEKHTVPIQHLAEVIGVLLKDM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *:. . . :*.*: :*:: .. * :: :* *:::* : ..*: * . ::.:. ::. **: *.* : *: ::* **:: : .* ** :* :: . **:::*: ::*: *:*** :.* *::*.:** *** *:* . * * :: : :* :*. * : ::.. * * :** .*:*:: *** * * * .. : . * *: * :.:**.* * *. ***. :.. * : .: *****:*::*::.* *: .. .*** ::***...: :..:: : : .* : ::* : . .* ** *: :: :* *: ::.. .:** ** . ", "identical_positions": 96, "similar_positions": 138, "identity": "15.38%" }, { "cls_id": "homologset.agr.SGD:S000000891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP99-1", "uniprot_id": "D3ZP99_RAT", "id": "D3ZP99-1", "name": "", "aln": "--MAAFAHLLKRLGWAA-----RAQEV--------TEQELEEECS--VPGAPWRLLVAPRCWQRLHGGAAAASGLRFGASAVQGWRARMEDAHCAQLALPGLPSG--WAFFAVLDGHGGARAARFGARHLPGHVLGE----LGPAP-------REPDGVRQALRSAFLHADSQLSKLWPRCDP----GGSTAVALLVSPRF--LYLAHCGDSRALLSRSGSVAFCTEDHRPHRPRERERIHDAGGTVRRRRVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALARQD-EDEFVLLASDGVWDALSGADLAGLVTSRLRLGLDPELLCAQLLDTCLCKG------SLDNMTCMVVCFPGAP-------------------RPCEEAISKEMALDAVLSHKVAGEQVKWPVGGMVGQCGLSAHLLLRAVCLCSGTSMPKHGFQDPGLRGHPGLASWRRATQQGHCHS------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGL1-1", "uniprot_id": "PPM1N_MOUSE", "id": "Q8BGL1-1", "name": "Probable protein phosphatase 1N", "aln": "--MAAFVRLLERLGWAA-----RAQQV--------VEQEVEEECS--VPGASGSLLAAPRCWQRLHRGAAATSGLRFGASAVQGWRARMEDAHCARLALPGLPSG--WAFFAVLDGHGGARAARFGARHLPGYVLGE----LGPAP-------QEPDGVRQALRSAFLQADAQLSALWPRGDP----GGSTAVALLVSPRF--LYLAHCGDSRALLSRSGSVAFCTEDHRPHRPRERERIHDAGGTVRRRRVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALARQD-EDEFVLLASDGVWDALSGADLAGLVTSRLRLGLDLELLCAQLLDTCLCKG------SLDNMTCMVVCFPGAP-------------------RPCEEAISKEMALDEALSHKVAELYAS-------AQEPPGLNTVFRTLASEDIPGLPPGGGLHS-KAAVIAEAYSKLHQTPGECQE--------EEW-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N819-1", "uniprot_id": "PPM1N_HUMAN", "id": "Q8N819-1", "name": "Probable protein phosphatase 1N", "aln": "--MAVLARQLQRLLWTACKKKEREKEG--------REEEEEEEAGRRAPEGPRSLLTAPRRAQRPHGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPG--WALFAVLDGHGGARAARFGARHLPGHVLQE----LGPEP-------SEPEGVREALRRAFLSADERLRSLWPRVET----GGCTAVVLLVSPRF--LYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQA-EDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKG------SLDNMTCILVCFPGAP-------------------RPSEEAIRRELALDAALGCRIAELCAS-------AQKPPSLNTVFRTLASEDIPDLPPGGGLDC-KATVIAEVYSQICQVSEECGE--------KGQDGAGKSNPTHLGSALDMEA------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49443-1", "uniprot_id": "PPM1A_MOUSE", "id": "P49443-1", "name": "Protein phosphatase 1A", "aln": "---------------------------------------------------MGAFLDKPKMEKHNAQGQG--NGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLET--WSFFAVYDGHAGSQVAKYCCEHLLDHITNN-QDFRGSAG------APSVENVKNGIRTGFLEIDEHMRVMSEKKHG-ADRSGSTAVGVLISPQH--TYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKG------SRDNMSVILICFPSAP-------------------KVSAEAVKKEAELDKYLESRVEEIIKKQV------EGVPDLVHVMRTLASENIPSLPPGGELAS-KRNVIEAVYNR-LNPYKNDDT--------DSASTDDMW-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20650-1", "uniprot_id": "PPM1A_RAT", "id": "P20650-1", "name": "Protein phosphatase 1A", "aln": "---------------------------------------------------MGAFLDKPKMEKHNAQGQG--NGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLET--WSFFAVYDGHAGSQVAKYCCEHLLDHITNN-QDFKGSAG------APSVENVKNGIRTGFLEIDEHMRVMSEKKHG-ADRSGSTAVGVLISPQH--TYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKG------SRDNMSVILICFPNAP-------------------KVSAEAVKKEAELDKYLENRVEEIIKKQG------EGVPDLVHVMRTLASENIPSLPPGGELAS-KRNVIEAVYNR-LNPYKNDDT--------DSASTDDMW-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35813-1", "uniprot_id": "PPM1A_HUMAN", "id": "P35813-1", "name": "Protein phosphatase 1A", "aln": "---------------------------------------------------MGAFLDKPKMEKHNAQGQG--NGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLES--WSFFAVYDGHAGSQVAKYCCEHLLDHITNN-QDFKGSAG------APSVENVKNGIRTGFLEIDEHMRVMSEKKHG-ADRSGSTAVGVLISPQH--TYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKG------SRDNMSVILICFPNAP-------------------KVSPEAVKKEAELDKYLECRVEEIIKKQG------EGVPDLVHVMRTLASENIPSLPPGGELAS-KRNVIEAVYNR-LNPYKNDDT--------DSTSTDDMW-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9J2-1", "uniprot_id": "A0A8M9Q9J2_DANRE", "id": "A0A8M9Q9J2-1", "name": "Protein phosphatase 1A", "aln": "---------------------------------------------------MGAFLDKPKMEKHNAHGDG--NSLRYGLSSMQGWRVEMEDAHTAVIGLPNSLDL--WSFFAVYDGHAGSQVARYCCEHLLEHITSN-PDFQGGGGGGGPAVEPSVDSVKSGIRTGFLQIDDHMRQISEKKHGGADRSGSTAVGVMISPRH--IYFINCGDSRGLLSRGGAVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVCAIERSEAEDEFIVLACDGIWDVMANEELCDFVRSRLEVTDDLERVCNEIVDTCLYKG------SRDNMSVVLVCFVSAP-------------------KVSPEAVKREAELDKYLESRVEEILKRQGD-----EGVPDLVHVMRTLASESIPNLPPGGELAS-KRSVIEAVYNK-LNPYRNEDT--------DPDILFFRGFS-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36993-1", "uniprot_id": "PPM1B_MOUSE", "id": "P36993-1", "name": "Protein phosphatase 1B", "aln": "---------------------------------------------------MGAFLDKPKTEKHNAHGAG--NGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLDN--WSFFAVYDGHAGSRVANYCSTHLLEHITTN-EDFRAADKSG-SALEPSVESVKTGIRTGFLKIDEYMRNFSDLRNG-MDRSGSTAVGVMVSPTH--MYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAE-EDEFVVLACDGIWDVMSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKG------SRDNMSVVLVCFSNAP-------------------KVSEEAVKRDSELDKHLESRVEEIMQKSGE-----EGMPDLAHVMRILSAENIPNLPPGGGLAG-KRHVIEAVYSR-LNPHKDNDG--------GAGDLEDS------LVAL----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35815-1", "uniprot_id": "PPM1B_RAT", "id": "P35815-1", "name": "Protein phosphatase 1B", "aln": "---------------------------------------------------MGAFLDKPKTEKHNAHGAG--NGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLED--WSFFAVYDGHAGSRVANYCSTHLLEHITTN-EDFRAADKSG-FALEPSVENVKTGIRTGFLKIDEYMRNFSDLRNG-MDRSGSTAVGVMISPTH--IYFINCGDSRAVLCRNGQVCFSTQDHKPCNPMEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAE-EDEFVVLACDGIWDVMSNEELCEFVNSRLEVSDDLENVCNWVVDTCLHKG------SRDNMSIVLVCFANAP-------------------KVSDEAVKRDLELDKHLESRVEEIMQKSGE-----EGMPDLAHVMRILSAENIPNLPPGGGLAG-KRNVIEAVYSR-LNPNKDNDG--------GAGDLEDS------LVAL----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B2A8-1", "uniprot_id": "A0A8M2B2A8_DANRE", "id": "A0A8M2B2A8-1", "name": "Protein phosphatase 1B", "aln": "---------------------------------------------------MGAFLDKPKTEKHNAHGAG--NGLNFGLSSMQGWRVEMEDAHTAVVGLPHGLDD--WSFFAVYDGHAGSRVANYCSKHLLEHIITSSEDFRSGPD--------SVEGVKIGIRSGFLKIDEYMRNFSDLRNG-MDRSGSTAVGVLVSPEH--LYFINCGDSRAVLSRAGQVRFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVFEVPRVSDEDEFVVLACDGIWDVMSNEELCDFVRSRLEVWDDLEKVCNSVVDTCLHKG------SRDNMSVVLVCFPNAP-------------------KVSEEAVKKEAELDKFLEARVEELMEKSGE-----EGIPDLSHIMHNLHPETIPNLPPGGGLPS-KRSVIEAVYNR-LNPHREEDGDSQGGAVGGEEEEEGSSAAAHLLEALRQFRVSHRGEYRQVLEQALSAYRMSCGTGATTRTAPQEEPSSPPPSPATEPLSTEEGQDETAPSQSPDKLSGAPTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N1Z489-1", "uniprot_id": "A0A8N1Z489_DANRE", "id": "A0A8N1Z489-1", "name": "Protein phosphatase 1B", "aln": "MRTARRASTMEVPSFLRQLVKETEKMVTFFFKGGRRDSGSDDDYYENDPDACSPYLERPILAKDSAEGESK-WGITYAMASMQGWRAQMEDSHTCMPEMSDALPD--WSYFAVYDGHAGRTVAQYSSRHLLDFILDT-----GCVT-----VEEDVEQVKDGIREGFLAIDRHMHTLS--RNESWDHSGSTAASVMISPRN--FYFINCGDSRTFLCRDGHVVFYTEDHKPCNPREKERIQNAGGSVTLQRINGSLAVSRALGDFDFKEVEWRAQTEQLVSPEPEVYELERSP-EDEFLVVACDGVWDAIGNEDLCAFVRNRLHVCDDLREICSQVIDLCLYKG------SLDNMTIIIICFDGAP-------------------KVTQEALQQEAELEQLIEQKVAEIIHVIRSK----DEEPDLLYVMKFLASEPIPGLPPGGGVSC-KRDCIIAAYQKYAAAFRPLEP-------MDTGGSDDST-------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZS1-1", "uniprot_id": "Q9VZS1_DROME", "id": "Q9VZS1-1", "name": "protein-serine/threonine phosphatase", "aln": "---------------------------------------------------MGQTLSEPVTAKESAYCQN--AAYRVGSSCMQGWRINMEDSHT---HILSLPDDPGAAFFAVYDGHGGATVAQYAGKHLHKYVLKR--------------PEYNDN-IEQALQQGFLDIDYVMLRNKTCGDQ---MAGSTAVVVLVKDNK--LYCANAGDSRAIACVNGQLEVLSLDHKPNNEAESKRIIQGGGWVEFNRVNGNLALSRALGDYVFKHENKK-PEDQIVTAFPDVETRKIMDDW-EFIVLACDGIWDVMSNAEVLEFCRTRIGMGMFPEEICEELMNHCLAPDCQMGGLGGDNMTVVLVCLLHG--------------------RPYSDL---------IARCRN-----------GSQATNNDQEEAGDATKDEVAKDEAEAETDTETETQTKPCQKQSNSGPM------------------------------DDEVKMASHLNKM------AAIESHYIYD------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0Q0-1", "uniprot_id": "Q9W0Q0_DROME", "id": "Q9W0Q0-1", "name": "protein-serine/threonine phosphatase", "aln": "---------------------------------------------------MGQTLSEPVTTKDTACCAN--ASYRVGSSCMQGWRVDMEDAHT---HILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKR--------------PEYRDNSIEVALKKAFLDFDREMLQNGSLDEQ---TAGCTAIVVLIRERR--LYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEFNRVNGNLALSRALGDFIYKKNLLKTPEEQIVTAYPDVEVLDITEDL-EFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEPELICEELMNSCLSPDGHTGNVGGDNMTVILVCLLHN--------------------KSYEDL---------AVRCG------------GKRKTP--VETVGDIQD--------------QSVKVVTPCS-QGSSGSS------------------------------TSRLGLGFGLRES------ETPEANL---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39966-1", "uniprot_id": "PP2C2_YEAST", "id": "P39966-1", "name": "Protein phosphatase 2C homolog 2", "aln": "---------------------------------------------------MGQILSNPVIDKESHSGAD--SLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQ--------------KSFHEGNLPRALIDTFINTDVKLLQDPVMKED---HSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLKEGEDVAQWSDRMKSKAHRTSVRSFADKRRRVFSYYDFSKCNDEQVFAITTKKPQDKFTRDHEAAVASVTAADNDDPMDIDDTDADTDAENLDPSSQSKSKTSGPIDLASLEALLGATGGVKTDSNGNKVTYTLPQSALAQLLQTMGHDPASSHPENDSNTDHKAGRSHLQ---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : . .. **** ***:* : : :.: ***.* .*.: :: : : .: *: * : . .*.** ::: :.**** . . : **:* * .** ..* : *::*.**:***:**: :* *:*: *:: :*:::*.**:** : . : : . :. ::: * . ***: :::.: : : ", "identical_positions": 54, "similar_positions": 74, "identity": "9.42%" }, { "cls_id": "homologset.agr.SGD:S000000895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNG4-1", "uniprot_id": "A0A8I5ZNG4_RAT", "id": "A0A8I5ZNG4-1", "name": "", "aln": "-------MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHS--EEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGN-DGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRS-WAGIINLCKPGN-SGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTDEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRD-QYLRVQKD---IFVLKDTEEALLINLR----------------------------------------------------------DSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYASLDLDFAK-SKQLTVVGCQFTEFLLES-EEDGQGYLEDLVKDIVQWLNASSGMK--PERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKVLTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQSIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEE--NVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHSWDSVRHSRKHLWPVVPDDVEQLCNE-------------LSSVPSTLSLNSESTSSRHNSESESAPSSMFILEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPTKKHRSSSDPKGGKLSSENKTSNRR-----IRTFTEPS-VDFNHSDDFT-------NISPAQKTLQLETSFVGNKHLEDTGSTPSIGDNDLKFPKSFGP-----ENHRENTSRERLVVES----SAGSHMKIRSQSFNT----DTTTSGISSMSSSPSRETVA-VDSTTMDTDCGSLSTVVSTKTVKTSHYLTPQANHLSLSKSNSVSLVPPG-------------------------SSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFG-----------YATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANS-------------FESRLTPSRIDFKKKHVGGIRSLRPTIANNLFRFMKALSYAS----LDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIP-----------------------YFQSKHVPPPDDRGARTFSHDGGGLPSGTGSLVKNSFHLLRQQMSLTEIMNSVHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILG-----------------------------FQPSNQLSSICSHSDLQDIPYSDWCEQPIHNPLEVVP-SKFSGISGCSDGASQEEGSASSTKSTELLLG------------VKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKY-PQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAIPPNQPIVDESAES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6QI06-1", "uniprot_id": "RICTR_MOUSE", "id": "Q6QI06-1", "name": "Rapamycin-insensitive companion of mTOR", "aln": "-------MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHS--EEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGN-DGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRS-WAGIINLCKPGN-SGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTDEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLNRFHEMKKRGPKPYSLHLDHIIQKAIATHHKRD-QYLRVQKD---IFVLKDTEEALLINLR----------------------------------------------------------DSQVLQHKENLDWDWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYASLDLDLAK-SKQLTVVGCQFTEFLLES-EEDGQGYLEDLVKDIVQWLNASSGVK--PERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLIKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQSIITELCHNVRTPDLDKWEDIKKLKASLWALGNIGSSNWGLNLLQEE--NVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHSWDSVRHSRKHLWPVVPDDVEQLCNE-------------LSSVPSTLSLNSESTSSRHNSESESAPSSMFMLEDDRFGSTSTSTFFLDINEDAEPAFYDRPGPIKDKNSFPFFGSSKLVKNRILNSLTLPTKKHRSSSDPKGGKLSSENKTSNRR-----IRTLTEPS-VDLNHSEDFT-------SSS-AQKSLQLEPSFVGNKHLEDAGSTPSIGENDLKFPKSFGT-----ETHRENTSRERLVVEG----SASSHIKIRSQSFNT----DTTTSGISSMSSSPSRETVA-VDPTAMDTDCGSLSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPG-------------------------SSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFG-----------YATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANS-------------FESRLTPS------------------------RFMKALSYAS----LDKEDLLSPINHNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQIKDVP-----------------------YFQSKHVPPPDDRGARMFSHDGAGLSSGAGGLVKNSFHLLRQQMSLTEIMNSVHSDASLFLESTEDTGLQEHTDDNCLYCVCIELLG-----------------------------FQPSNQLSSICSHSDLQDIPYSDWCEQTIHNPLEVVP-SKFSGISGCSDGASQEEGSASSTKSTELLLG------------VKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKY-PQTFDDICLYSEVSHLLSHCTFRLQCRRFIQELFQDVQFLQMHEEAEAVLAIPPIQPIVDESAES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6R327-1", "uniprot_id": "RICTR_HUMAN", "id": "Q6R327-1", "name": "Rapamycin-insensitive companion of mTOR", "aln": "-------MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHLNNFTKLLCDIGHS--EEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGN-DGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRS-WAGIINLCKPGN-SGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRD-QYLRVQKD---IFILKDTEEALLINLR----------------------------------------------------------DSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAK-AKQLTVVGCQFTEFLLES-EEDGQGYLEDLVKDIVQWLNASSGMK--PERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEE--NVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNE-------------LSSIPSTLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRR-----IRTLTEPS-VDFNHSDDFT-------PISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGT-----ENHRENTSRERLVVES----STSSHMKIRSQSFNT----DTTTSGISSMSSSPSRETVG-VDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSNHLSLSKSNSVSLVPPG-------------------------SSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFG-----------YATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANS-------------FESRLTPS------------------------RFMKALSYAS----LDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIP-----------------------YFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILG-----------------------------FQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVP-SKFSGISGCSDGVSQE-GSASSTKSTELLLG------------VKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKY-PQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QEG1-1", "uniprot_id": "A0A8M9QEG1_DANRE", "id": "A0A8M9QEG1-1", "name": "", "aln": "MMNVPANMAVSIRGRPTRSVRMRGRNDSGEENVPLDLTREPSDNMREILQNIAKSHGVSNMRKLGHLNNFVKLLNSVSHC--EEKLGFTHEEIIICLRVALLNEVKEVRAAGLRALRYLIRDSSILQKVLQLQVDYLISRCIDIQQSNEVERTQALRLVRKMITVNAQLFPSSVTNSLIAVGS-DGLQERDRMVRACIAIICELALKNPEVVAQRGGLSTILKNVIDCQLSRINEALITTILHLLNHPHTRQFIRADVELEQILAPYTDFHYRHNPETAEAQIKEDREARFLASKMAIVAAFRS-WSGIINLCKSGN-SGVQSLIGLLCIPNMDVRKALLEVLYEIFRLPVPLVTGDFEEALHSVDPSRFQDSWRLSDGFVAAEAKVILPHRARSRPDLMDNYLALLLSAFINSGLLEGLVEVVTSSDGQISVRATILLGELLHMANTILPHSHSHHLHCLPTLINMAASFDISQEKRLRASAAVNHLKRFHEKKRRGPKPYSLYLHHILHRTSSSSHRRDQQHHRPHKD---IYIMKDTEEALMMNLR----------------------------------------------------------DSQILNHKQNLDWNWILIITILKWPNVNLKNIKDEQMHKFVRRLLYFYKPSSKLYSALELDHAK-ARQLTVAGCQFNQFLLDS-EEDGQSYLEELVKDIVQWLTSSSGLK--PERSLHSNGLLTTLNQHYFLFLGTLSAQPHGVKMLEKCGVFQCLLNLCSMKNQDHLLKLTVSTLDYSRDGLARVILSKILTAATDNCRLYATKHLRVLLRANVEFFSNWGMELLVTQLHDHNKTISMEALDILDEACEDKANLHALIHMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVSKQLEKWLKEYNLKYVDMIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPNVFLPVHLYGQLVHDKTGCLLLEAQGVIPDLSYTVRSPVLDKWEGVKQLKAALWALGNIGSSNWGLNLLQEE--NVIPDIIALAQHCEVLSIRGTCVYVLGVISRTRQGSDVLKASGWDSVRHSRRQQWPVVPDEVEVPLPS------------ELSSVPSTLSLNSESTSSRHNSESES-QPSLYFMDDD-REGL-------DIYEDSS--LSMHAKTSKERSPFTILTPS-HLRNRFLNSLSLPSKKGRSPTDTKGTSFTAKTPDELRL--MHCNRSIAEVANSSPGHSEVF-----YNGSRMPRSPTVSLETSFVGIKALAEPYATDSESRN---------------QYKRERNSRERLTCDGASVLPGGGTFKSRSQSFNT----DTTTSGISSMSSSPSRE-------PAMDTDCASLNTVVSARTVKMQHSLSP-NNHILLSKSNSTSLVPPG-------------------------SAHTLPRRAQSLKSPSVATIKSLVDCSYMYTSPRDALG-----------YATLKRLQQQRIHPSLSHSEALASPAKDVLFTDTITMKTRS-------------LDSRLTPRRCSPKRYFGP-FSSSRRLSRTFVPWFLKALSFAS----LDKEDLLSPINHSTLQRSSSLRSMVSSATFGCSEDYIGLALPLDINNMFQIKETS-----------------------YFQKRTSPPAGDKSSKFNFGESDGFLESCRGPP------LKQQVSITELLNSSRSEQHHLLGAEETTGLQEHTEQNCLYCSAINALG-----------------------------SHTHSHLNNTHNHNDLSDG-FSQWHSQPSHNHLEVVAQSKFSGVSGCSDAAVSQ-GSACSTPSTEIILG------------GKAISEDGPACRVLLRKEVLRLVINLSSSVGTKGHETGLLTIKEKF-PYAFDDICLYSEVSFLLASCTFRLASRRFIQELFQDVQFIPLYDEAEAVLTKPSVEDAES-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B4Q4-1", "uniprot_id": "A0A8M3B4Q4_DANRE", "id": "A0A8M3B4Q4-1", "name": "", "aln": "--MCLVKMAVSIRGRPIRSIRMRGRNDSGEENVPLDLTREPSENMREILQNVAKQQGVSNMRKLGHLNNFIKLLCNVGHS--EEKFGFTYEEIIICLRLALLNEAKEVRAAGLRSLRYLIRDSNILQKVLRLQVDYLISRCIDIQQSNEVERTQALRLVRKMITVNALLFPSSVANSLIAVGN-DGPQERDRMVRACIAIICELALENPEIVAKRGGLSTILKNVIDCQLSRINEALMTTILHLLNHPHTRQYVRSDVELEQILAPYTDFHYRHNPDTAEGQLKEDREARFLASKMSIVASLRS-WSGIINLCKSGN-SGIQSLIGLLCIPNMEVRRGLLEVMYEIFRLPVPVVTQDFIEALLSVDPSRFQDSWRLSDGFVASEAKIILPHRARSRPDLMDNYLALLLSAFIHSGLLEGLVEVITSSEDSVSVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPQGKRLRASAAVNYLKRFHEKKKRGPKPNSLYLDLIVRKSLAAHYCRD-QHLRPQRD---IFVIKDTEEALMMNLR----------------------------------------------------------DSQILNHKQNLEWNWVLISTILKWPNVNLRNNKEEQMHKFVRRLLFFYKPSSKLYASLELDYSK-ARQLTVVGCQFIEFLLES-DEDGQGYLEDLVKDIVQWLSASSGLK--PDRSLQSNGLLTTLSQHYFLFLGTLSANPQGVKMLEKCSVFQCLLNLCSLKNQDHLLKLVVSTLDYSRDGLARVILSKILTAATDNCRLYATKHLRVLLRANVEFFSNWGIELLVTQLHDRSKAVSVEALDILDEACEDKANLHALIHMKPALTHLGDKGVLLLLRFLSIPKGFSYLNERGYVSKQLEKWQKEYNLKYVDLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPNVFLPVHLYGQLVHDKTGCHLLEAQNVVSDLSYTVRCPLLDKWEGIKQLKAALWALGNIGTSNWGLNLLQEE--NVIPDIVALAHDCEVLSIRGTCLYVLGLISKTKQGCEVLKLHGWDAVRHNRRQLWPVVPDEVEQHQNLQQQQQQHQQPLIHLSSAPSTLSLTSESTSSRHNSESDSIQPTMYILDDEKLESS-------ELSEDQP--LYFRPKLLKDRSPFTILASSRLVRNRFLISLSG--KKLRSTSDPKGTGSSSKLQGELTLGGLRRVRTVTEPSIFSSSQGDVFSP--VFTDGHLPKSPSVSLETSFVGTKTLDTQDSTSSIGEQEVRLNRTAERSSGVGDTHREQTSRERLAGDGSTSGSG-AQFKSRSQSFNT----DTTTSGISSMSSSPSRETVGCVDSSTIDTDCVSLNTVISTQTVKTLHSLTPQSNHLTLSKSNSVLLMPPG-------------------------SSHTLPRRAQSLKSPSVTTISSLTDCSFMYTSPRDALG-----------YATLKRLQQQRIHPSLSHSEALASPAKDVLFTDAITMKTGS-------------LDSRLTPRRCTKKRFRCLGQGSSRPHRRSLLPRFLKALSFAS----LDKEDLLSPISQTSLQRSSSVRSMVSSVTYGSSDDYIGLALPMDINSMFQIKDTP-----------------------YFQKRKSPPSEDRAAKFFSGEADGSSEVSRHSV------LRSQLSITELIAVSRMEKHQMLGAEET-GLQEHTEENCLYCAGLYVLG-----------------------------CNSSSATQSRTDYPDAT---FSEWCNQSIHN-LEVMPQSKYSGVSGCSD-AVSQ-GSGGSTRSTELVLG------------VKNIPEDAPACRVLLRKEVLRLVINLSSSVGTKGNETGLLTIKEKF-PYAFDDICLYSEVSYLLAHCMFRLASRRFIQELFQDVQFIPMYEEAESILSMPKKTTTVDLPSDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWJ6-1", "uniprot_id": "Q9VWJ6_DROME", "id": "Q9VWJ6-1", "name": "", "aln": "--MASQHSSWRFGKRSKLQLRIKVSQDP-EDFYRLDPQRSAAENAFEIYS-MLCLEETRDTKRLFLLNALASLCLGARKGSHHSNIRFTTEELLYCLSASLVHTFTQVRAAALRTIRYAISTPNDIKTFNALQLQHLLCRSIDLMLKNDDERVQALKLVRKMLAIAPEDISPAVVRCLVSLAD-SGIEENDNLLRACLATLAEFAVLNPALLIVCGGVTSITRNVLECHNPRIAESLCGVLLYLLEWPQTRNICG--VRLDCLAAPYCDFTYRQSIVDKN---KDARELRYTSCRLALLSVLRS-WTGTLEFCDPSKPSGLKAIVDALYLNQIEVRKAILDLLYELLTLPQPTWTDDYAVALQAVDPSDFQDTWLLSNGFVSAEGRSILPTLAARAPSVVEQHLALMLYCFLETGLLNALVEVVVSSDQFVSVQATVLIGKILQLMHTHLPPDICCTSPALPTLVSHATLGNQ------QANAAVAALQNYQKLLRQRPASRSLFLDSIIQGGALIQTRLFRRHLNVQEQAGPVLQLQETAEAAAFAVPPVTQFRGTLDRSRLDSVSSSDESNSQASTSSRSSFRLKRKFLPQALYDNFRAFNRLLTDSRVLSQADAHLWDWDVITTILKS---NLIRKLDYTQGKFLKRLVDFYKPRNNRFSHQDLVPGQRLPTYVSAGLDLIDVLLSSNELECMRFITDYFSDISQQLAAVTTSNRAHDCLFSPQHMNNTMCQQYFLYIGRMCRTVKGIEVLKNTTVFEYLINLVRVTDHVCYVKLIVSGLNYSYEKLPRQVLEKALTSAKTRGRLYSTQFMAVLLRARLPHFEVWGIPLIINQTRDSDRSVGLAAMDVLEEACHDKYYLEEIVSRWPNLTHRGDAGRLLMARYYSLPRGLNSTMAR--IEDEIRYWRNGYNKRYVLLVEADTHSSLTLHIRNEDGYYSRRNCNQRPQTVPPNVAPHLYGQMAQTGQGMTALRKHGDLPQLLELLRRAKCTDDAECLELKAAIWALAHASTHSNGIEYFVELNARLYEKLIVLVTKCEVYSVRATCFSALGLIAGTQAGANILFKLNWLSVRHDKNTMWPVHQPEDWMSSQYTP-----------VRHYYEDVPADNMTMMDDYIERFYETGSDFWHMLADQTDASGGGGGVAGTVVGMHPIVQDPNATITTTD--SVRTTTDDVHPRMLVGVAAKSKTLPEGSNLRQGKHQRSLSESKTTDVISLLGSGVGTMSGAVLYPTPYQHRIRYNSCTDSNTSGVSSCESVTGRTAAAYAAAANELQQFPLSPIPSMSNLLESDELFRRNQLATSMLPSTLSPMAMKGYVQLRSLRKHSRPVFSESSAEFYDFAEILDTPEVQMRKLDWTHSHRRLKVRSLDRQLSDVYRRLSADELNVLLPTLNAPKFLPPNDLKGPCYAGICLPKNVLDLFPTRNLSRTYVSRDIQDQDIVGINLLNTMLRPQCLNDSLTNEGGDESSVISSLSDVSSASRRQTRQLQQGAKHSRSLCLHCARSPRQQRNDSGSHSNGGGGASLAPCELYSSAAAALVAAGIQAGPVLAKKSGSSAQGASAALGADISFHSPESMLSEDSLPDRLTASILYNVQRLANPVSAKQSKMALLELKQKHPHAFQDICLYSEACKTIGRSSYRMIARRFLQELFLDLNFDSFYVEPQLIIGARKFSAEEKAEATAPTAMQAMPFKQTILKPKPAAQLASVYETSWENLLMDQSPRINKSSPADQPANAQTKAKARNQLHIDDTESSLSSTDGENDSGEDVCDGSGAGTQASSVTTAHTALPTGNSNRSSIGTCTASQLVPGAATSNSAGAGTSASDNASTSLKNENRQFTRGRFYTLELDLSCTKNKFPIKNRSQRTPTPPPIESLIESKPTVQTDVNTSALPIMQRTGG-SNDSSSALRYSTVTKSLSASMARPVGSLYCEKRLQSSKSEAVLDEVAKARRASGGVGLTTVRDNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40061-1", "uniprot_id": "TSC11_YEAST", "id": "P40061-1", "name": "Target of rapamycin complex 2 subunit TSC11", "aln": "---------MSIPHSAKQSSPLSSRRRSVTNTTPLLTPRHSRDNSSTQISSAKNITSSSPSTIT------------------NESSKRNKQNLVLSTSFISTKRLENSAPSPTSPLMARRTRSTMTKALLNLKAEINNQYQELARLRKKKDDIEHLRDSTISDIYSGSYSTNHLQKHSMRIRANTQLREIDNSIKRVEKHIFDLKQQFD--KKRQRSLTTSSSIKADVGSIRNDDGQNNDSEELGDHDSLTDQVTLDDEYLTTPTSGTERNSQQNLNRNSTVNSRNNENHSTLSIPDLDGSNKVNLTGDTEKDLGDLENENQIFTSTTTEAATWLVSDYMQSFQEKNVNPDFIAQKANGLVTLLKEHSEIRKDLVLTS-FMSSIQNLLLNGNKLIAASAYRVCRYLINSSIFIDELLELRLDAFIIISLAKDNSFQIEREQALKMVRRFIEYNNGVTQGIMQAIISCVE--------KPEDSLRHMALETLLELCFVAPEMVKECRGMRVIEGFLQDYTSFSLASVILDTILQLMATHKTRQHFLEDFN-----------------------------------------------------------VSVLTTVFSDTNTKSNVNVEKMQNASTLISITLNSYNGFMLFSNNNFKPLKQLVSFFQIPICA-------------------------QYLIDIFLDVLKIKPLPYKPR-----GRHSHSFKPIPSQYYKECMSVNQRLALIVLILENSEFVPHLLELLNEEDRDDHLVAKGRYLLTEYFNLRMNLVDKKYTSVSKPIYKENFTYVN----------ETFQFKKIAYKMNRNRNTIGMSGIDYAQNIKSFSKNIKENTLLREVDDFRFRR---MVYDSKVLQTKDFTRWNWNIINELLEGPLLNKKQLEELVKSTKFIRRLLVFYRPLRLRFSNVNKGAKLSQKYVQVGCQFFKTLTATPEGMKILMDDTKIIPQLASLMFRAMEG---------------NISGNIFNKNKLREK-------------------IIFGYFKFIGILTQSKNGVHILTRWNFFTVIYKMFQFESKLGLEFLLLTIP-------------------ELDLKYSSHCRVIIGKALVVANEKVRIEATKHIGD-----------------KLKELLSTKESDLKLKANKVKLQQFKMEMLTRQLYDLSPSVVAVADQALYECIVAGNG------SEELGTSFRMFLNQMVFIR----------SPILFELLSRPYGFQLLNEINFVKEERDSWLSK-----------KNIEYVHIVEEFLKKN-------ESINAKSLTFQQ-----------------------------------------KSRLPLHFYESLTKTEDGILLLSQTGDLVTFMN----------------------------VIKKYVNGNNMATVENAKEILDLKAALWCVG--------------------FIGSTELGIGLLDNYSLVEDIIEVAYNASVTSVRFT----------------------------------------------AFYVLG----------------LISMTREGCEILDEMGWNCCVSVQDEPIGIALPNRLDRFLSYNEHK----------------------------WSAFGEYSDEMIVFNKSDGD--------------LIEKCLPIEFDLDKLLKEKDTAENPLNEKIITNKYDNDITSQTITVSG----------------------------------ENSSLFAN-------------------------------EGLSSPYVTQYRNDDDS----------------------------------IESKVLHIVSQLGNHILSNHAVKEITEINNKYGPRLFENEKMFFKVFNMMSKYRFKPHVRKFLCGLFINNRALENVIRHDNKRDKRPANFTR------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : * * . :* . ... :::: . : : .: .: .. : . *: : :. : : *: . : . : : .* *. :: : :: .:.: : * :. * : : . :. : ::. . . .* : . : . : :* : . . : : . : :: : : * . : . ::. *:. *::: . :* .. *: .:: **: ::.. . . : : *:: . : . : :::. . . . *: : * . : : :.* : . :* : . .* *: :** .: : :: :: : . *: : . : : * * :. : :*:: .. *::* :: : * . * ::.* *:.. .: . : : : : . .::. .:* :: . :. . :: : : . :. : : . . * . : . . : . : ::: :. * * . : : : . . : : * : . :*::: :: * .:* .: :* :. . : : : . : . . . . . :: : :: . : .. * . . . . : . .: :* : . . . *: : * . .. . . : : :. . : . : . . .: . .. :* : :. : . : . : * :: : .: . . : : . : . . * . : . .. : :: . . . . .. : * :: : : : . : . ", "identical_positions": 54, "similar_positions": 338, "identity": "2.74%" }, { "cls_id": "homologset.agr.SGD:S000000896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40112-1", "uniprot_id": "PSB3_RAT", "id": "P40112-1", "name": "Proteasome subunit beta type-3", "aln": "MS-VMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1P1-1", "uniprot_id": "PSB3_MOUSE", "id": "Q9R1P1-1", "name": "Proteasome subunit beta type-3", "aln": "MS-IMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKITTRTLKARMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49720-1", "uniprot_id": "PSB3_HUMAN", "id": "P49720-1", "name": "Proteasome subunit beta type-3", "aln": "MS-IMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8J0-1", "uniprot_id": "D3Z8J0_RAT", "id": "D3Z8J0-1", "name": "Proteasome subunit beta type-3", "aln": "MS-IMSYNGGAITATKGKNCVAIAADRHFRIQAQMVTTDFQKIFPMGYRLYIDLAGLGTDVQTVAQHLKFRLNLYELKEGQQIKPYTLLSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCSMVTNDFVVSGTCSEQMYGMCESLWEPNVDLEHLFETISQAMLNAVDQDAMSSMGVIVHIIEKDKITTRKLKAQMD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9XYN7-1", "uniprot_id": "PSB3_DROME", "id": "Q9XYN7-1", "name": "Proteasome subunit beta type-3", "aln": "MS-ILAYNGGCVVAMRGKDCVAIATDHRFGIQAQTISTDFKKVFHIGPRMFLGLTGLQTDILTVRDRLMFRKNLYETRENREMCPKPFSAMMSSFLYEHRFGPYFIEPVVAGLDPKTMEPFICNMDLIGCPNAPDDFVVAGTCAEQLYGMCETLWKPDLEPDQLFEVIAQSIVNAFDRDAMSGWGATVYIIEKDKITERTLKTRMD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25451-1", "uniprot_id": "PSB3_YEAST", "id": "P25451-1", "name": "Proteasome subunit beta type-3", "aln": "MSDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *** : * **:***** * :: *: ::..*:*:* * ::::.::** **: *: : : :: ***: :* : : * .: :::. ***:*****: **:**::.*: :***..:***** ..**:*:**.::*::****:*::*::: :.***.*:*:::** *:**:*. *. *::*:**::. * ** : *", "identical_positions": 82, "similar_positions": 79, "identity": "39.81%" }, { "cls_id": "homologset.agr.SGD:S000000897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08297-1", "uniprot_id": "RAD51_MOUSE", "id": "Q08297-1", "name": "DNA repair protein RAD51 homolog 1", "aln": "------------------------------------------------------MAMQMQLEASADTS---VEEE-SFGPQPISRLEQCGINANDVKKLEEAGYHTVEAVAYAPKKELINIKGISEAKADKILTEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARGFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06609-1", "uniprot_id": "RAD51_HUMAN", "id": "Q06609-1", "name": "DNA repair protein RAD51 homolog 1", "aln": "------------------------------------------------------MAMQMQLEANADTS---VEEE-SFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I2J2-1", "uniprot_id": "A0AC58I2J2_DANRE", "id": "A0AC58I2J2-1", "name": "DNA repair protein RAD51 homolog", "aln": "-----------------------------------------------MCYEGVNMAMRNASRVEVEAE---VEEEENFGPQPVSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27297-1", "uniprot_id": "RAD51_DROME", "id": "Q27297-1", "name": "DNA repair protein Rad51 homolog", "aln": "--------------------------------------------------------MEKLTNVQAQQE---EEEE--EGPLSVTKLIGGSITAKDIKLLQQASLHTVESVANATKKQLMAIPGLGGGKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITEIFGEFRCGKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPERLAAIAQRYKLNESEVLDNVAFTRAHNSDQQTKLIQMAAGMLFESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFGVAVVITNQVTASLDGAPGMFDA--KKPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESEAMFAILPDGIGDARES--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25454-1", "uniprot_id": "RAD51_YEAST", "id": "P25454-1", "name": "DNA repair protein RAD51", "aln": "MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGM-AFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ... : . :* . .: :* .*. *:* *.:.. **.*:** *.:*:*: * *:. .*.:::: ** ::**:** :* *: *:::: ::****:**.** **:*******:***** **:*:*********:*:. *****.:*****.**** ** ::*:*: * .:.*:***::*..*:*:* :*: *: *: ***::*::***. ****:*: *****:*** **. *:* * ****:******:****.*.:**. * . ******:*:**:***** ::**:* *:**: *******:*.:*** **:**.:: ", "identical_positions": 169, "similar_positions": 106, "identity": "42.14%" }, { "cls_id": "homologset.agr.SGD:S000000898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60924-1", "uniprot_id": "DELE1_RAT", "id": "P60924-1", "name": "DAP3-binding cell death enhancer 1", "aln": "-MWRLTGILGRALPRLLGPGFRGITPKPTSSDGPQTTSTTLPLP--RVNFDRSGSHGSKR----NRDPKCCGWKEAFHWMSAHVSPNTLRDAVSWGTLAVLALHLARQIHFHAPLVAGPQSAERCSWHSPLYRFLSSSWWHPHSSLRRHVLPSPDCPAPRNTGLREPRLGQEE-----PAARSQGLPSDSSLKPGLLNLPEEEPSDFGFLNASRDFTSQAKAAEAG--PPGGKNEQDKPKALPLEEAVTSIQQLFQLSVAIAFNFLGTENIKTG--DYTAAFSYFQKAADRGYSKAQYNVGLCLEHGRGTPRDLSKAVLFYHLAAVQGHSLAQYRYARCLLQSPGSMSDPERQRAVSLLKQAADSGLTEAQAFLGVLFTKEPHLDE--QKAVKYFWLAASNGDSQSRFHLGICYEKG-LGVQRNLGEAVKCY---QKSAAMGNEPAQERLRTLFNVEAAGPSHLAIGLKSFSSPSLCSLNTFLAGASGLPHASSTGNLGLLCRSGHLGTSHGAPSRAMPSLERSLVRLGFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39000-1", "uniprot_id": "SHC1_YEAST", "id": "P39000-1", "name": "Protein SHC1", "aln": "MSMTICSNTPGAYPEIG--AYNEVDKQLESSGFSSDSSLILNKPEVRQYWSSVSSHISRSGDVFTNDKEKISSSIGEDAMDIDASPSLIEKYNSFPTRKILPEQDEFENDVEDDASSSLKEKSQGSCEIEIASEISSEILNGTSADGNSEFHDFAEPPPSQNESVALSFSQSNDLDFLNNPSGSGSSNDINRSTSSISLPRHVSLDFNVYNS-LCLTNEVTASESHNVAKFHLGKKNKKSLLPRWKTIEMYGEVVKKTQDIYSNFQYAQYILRVGLDTEKLHELVKELEDESNSFSVDSLKEYLVN--------DAKVILKKLSAVG---YPDAQYLLGDAYSSGVFGKIKNRRAFLLFSAAAKRMHIESVYRTAICYECGLGVTRNAPKAVNFLTFAATKNHPAAMYKLGVYSYHGLMGLPDDILTKMDGYRWLRRATSMASSFVCGAPFELANIYMTGYKDLIISDPDYAMALYEKAAALGHTESARILEDARRSGGFVSRGHPPSAQKYHKTSHEAVAAKKLI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *.: .:. : : **. .. :* * * * :. .** *: ..* : . . . . *. ..**. :.. *: * :*. : : ... :. :. .: * . : :**. : *: . : . *.* :. :.*.: . ..* ..* . ... :.**.. . **.. *: :*.:..*:*: . .:::* . ** ::: ::.: : * ** :: * * .. .:: *.. * : .: * : . *:: :*:** .: :* *.* :.. :.:**. *:. **. *: .: : : . ***::: :**::... : ::**: :* :*: :: :. * :::::*... . * *: :* ..* *. .:: . . :: *. .: . *::.*. .:.: : . :.*: ", "identical_positions": 79, "similar_positions": 195, "identity": "14.88%" }, { "cls_id": "homologset.agr.SGD:S000000900", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62069-1", "uniprot_id": "UBP46_MOUSE", "id": "P62069-1", "name": "Ubiquitin carboxyl-terminal hydrolase 46", "aln": "-------------MTVRNIASICNMGTNASALEKDIGP-----------------------------------EQFPINEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGK-------------------------LKNG----NMNEPAENNKP-------------------------------------ELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62068-1", "uniprot_id": "UBP46_HUMAN", "id": "P62068-1", "name": "Ubiquitin carboxyl-terminal hydrolase 46", "aln": "-------------MTVRNIASICNMGTNASALEKDIGP-----------------------------------EQFPINEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGK-------------------------LKNG----NMNEPAENNKP-------------------------------------ELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M625-1", "uniprot_id": "UBP46_RAT", "id": "F1M625-1", "name": "Ubiquitin carboxyl-terminal hydrolase 46", "aln": "-------------MTVRNIASICNMGTNASALEKDIGP-----------------------------------EQFPINEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGK-------------------------LKNG----NMNEPAENSKP-------------------------------------ELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5WWB0-1", "uniprot_id": "UBP46_DANRE", "id": "A5WWB0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 46", "aln": "-------------MTVRNIASICNMGTNASALEKDIGP-----------------------------------EQFPINEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKVQQKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTVADILQEERKQEKQNGR-------------------------LKNNGTAIATDTEPEQNKI-------------------------------------DPTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--TSITHCLRDFSNTETLCSEYKYYCEMCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSGDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D0RB01-1", "uniprot_id": "UBP12_RAT", "id": "D0RB01-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "---------MEILMTVSKFASICTMGANASALEKEIGP-----------------------------------EQFPVNEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFRDKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR-------------------------LRNG----DVDSEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A8N5-1", "uniprot_id": "A0A8I6A8N5_RAT", "id": "A0A8I6A8N5-1", "name": "ubiquitinyl hydrolase 1", "aln": "-------------MTVSKFASICTMGANASALEKEIGP-----------------------------------EQFPVNEHY---------------------------------------------------FGLVNFGNTCYCNSILQALYFCRPFRDKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR-------------------------LRNG----DVDSEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMK--KLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES---RDFQSRD--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9M2-1", "uniprot_id": "UBP12_MOUSE", "id": "Q9D9M2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "---------MEILMTVSKFASICTMGANASALEKEIGP-----------------------------------EQFPVNEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR-------------------------LRNG----DVDNEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPLILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75317-1", "uniprot_id": "UBP12_HUMAN", "id": "O75317-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "---------MEILMTVSKFASICTMGANASALEKEIGP-----------------------------------EQFPVNEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR-------------------------LPNG----NIDNENNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4FUN7-1", "uniprot_id": "UBP12_DANRE", "id": "A4FUN7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12A", "aln": "---------MEILMTVSKFASFCTMGANASALEKEIGS-----------------------------------EQFPVNEHY---------------------------------------------------FGLVNFGNTCYCNSVLQALYFCRPFREKILAYRSQPRR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIANQKRKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEERKQDKQNGK-------------------------LANG----TLDSQNNNSTPP------------------------------------STTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMRVKKLPMILALHLKRFKYMEQLQRYTKLSYRVVFPLELRLFNTSGDATNPERLYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSEISKNSESGYILFYQSRD--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCT9-1", "uniprot_id": "UBP12_DROME", "id": "Q9VCT9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12/46 homolog", "aln": "------------------------MGANVSQLEREIGS-----------------------------------DLFPPNEHY---------------------------------------------------FGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KETLLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAERNAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQVDVDQN--TSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRHIKVSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGL-WLLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGYILFYQSRDCA------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39967-1", "uniprot_id": "UBP9_YEAST", "id": "P39967-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9", "aln": "MIKRWLSVNRKKSHPEKNTQGNDEINRKATSLKKTKGSGDPSIAKSPSAKSSTSSIPSNLASHERRSKFSSQTDNLAGNKHYHEHYHNMASTSDEREYDSSTTYEDRAFDTESSILFTTITDLMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPERVAAVNRIRKSDLKGSKIRVFTNESFETSTNSGNSNTGYQSNDNEDAHNHHHLQQSDQDNSSSSTQEKQNNFERKRNSFMGFGKDKSNYKDSAKKDDNNEMERPQPVHTVVMASDTLTEKLHEGCKKIIVGRPLLKQSDSLSKASTTDCQANSHCQCDSQGSRITSVDDDVLVNPESCNDAVNNSNNNKENTFPTSEQRKKAALIRGPVLNVDHLLYPTEEATLYNGLKDIFESITENLSLTGIVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQ-------------------------------------KTDNSND---------------------------------------NFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVY--KKYELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQ----TTAYVLFYKETQADKTENQNENIDTSSQDQMQTDNNIEQLIKCDDWLRDRKLRAAANIERKKTLGNIPEVKTAETKTPLNDKKRNKQKRKSRILSFIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :.: *:: *. : :. *:** ** *******.**:**.** ** ::* * : : .* . * *:* **: : .* :.*.:*:. *:**: *:. **********:*:* . : : :. . . :... .:: ::*:* **.. :**.*:.::*:** *:*: ::*: : *.* : *: : : * * . *: *: * . ***.: : :** **:******** :: : *: ::::** * : .* . :. : *:* .**:* ****::***: * :.. : ***:**: *:.*. .:: :* * ..: : ::. : ", "identical_positions": 112, "similar_positions": 124, "identity": "13.4%" }, { "cls_id": "homologset.agr.SGD:S000000901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CS42-1", "uniprot_id": "PRPS2_MOUSE", "id": "Q9CS42-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGE--INDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENITEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINSAAFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09330-1", "uniprot_id": "PRPS2_RAT", "id": "P09330-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGE--INDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENITEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11908-1", "uniprot_id": "PRPS2_HUMAN", "id": "P11908-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGE--INDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60892-1", "uniprot_id": "PRPS1_RAT", "id": "P60892-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGE--INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7G0-1", "uniprot_id": "PRPS1_MOUSE", "id": "Q9D7G0-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGE--INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60891-1", "uniprot_id": "PRPS1_HUMAN", "id": "P60891-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGE--INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UXL2-1", "uniprot_id": "G3UXL2_MOUSE", "id": "G3UXL2-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MSNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGE--INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21108-1", "uniprot_id": "PRPS3_HUMAN", "id": "P21108-1", "name": "Ribose-phosphate pyrophosphokinase 3", "aln": "-----------------------------------------------MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGE--INDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTSIADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAGATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT33-1", "uniprot_id": "Q9VT33_DROME", "id": "Q9VT33-1", "name": "ribose-phosphate diphosphokinase", "aln": "MPDKKCTENEQNDCVMPVRSANPIRARSLIRDNLEKQAGCLNLIHSRMPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGE--INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38620-1", "uniprot_id": "KPR2_YEAST", "id": "P38620-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "---------------------------------------------MSTNSIKLLAGNSHPGLAELISQRLGVPLSKVGVYQYSNKETSVTIGESIRDEDVYIIQTGYGEHEINDFLMELLILIHACKTASVRRITAVIPNFPYARQDKKD-----------------------KSRAPITAKLIANLLETAGCDHVITMDLHASQIQGFFHIPVDNLYGEPSVLNYIRT-KTDFNNAILVSPDAGGAKRVASLADKLDMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGTLVKACDTLMDHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTVPVD---LDLDIVDQVDISPTIAEAIRRLHNGESVSYLFTHAPV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :::*.** .*:: : :***: *.** . ::** **.* *.**:*.*****:*:* ** *** ******:*:*** ** *:***** ********** :**:**:***:**:*. **.**:**************.*******.**:**::*: .::.*. :***********:*:**:*:::********:***** ::***** .: .:*:******* *: *.* *:. **..* **:*******.* .:: .: :. :* ***:* : . : :*:* :***:** **********::.* ", "identical_positions": 182, "similar_positions": 85, "identity": "46.67%" }, { "cls_id": "homologset.agr.SGD:S000000902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K8C5-1", "uniprot_id": "A0A0G2K8C5_RAT", "id": "A0A0G2K8C5-1", "name": "Ubiquitin-conjugating enzyme E2 J2", "aln": "MHQAKALDSARKMSSNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKKQLAAQSLVFN-LKDKVFCELFPEVVEEIKQKQK------AQDELSN----RPQNLP--LPDVVPDGEMHRG-----QNGIQLLNGHAPAAGPNLAG----LPQANRHHGL-LGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P073-1", "uniprot_id": "UB2J2_MOUSE", "id": "Q6P073-1", "name": "Ubiquitin-conjugating enzyme E2 J2", "aln": "------------MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKKQLAAQSLVFN-LKDKVFCELFPEVVEEIKQKQK------AQDELSN----RPQNLP--LPDVVPDGELHRG-----QHGIQLLNGHAPAAGPNLAG----LPQANRHHGL-LGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2K1-1", "uniprot_id": "UB2J2_HUMAN", "id": "Q8N2K1-1", "name": "Ubiquitin-conjugating enzyme E2 J2", "aln": "------------MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFN-LKDKVFCELFPEVVEEIKQKQK------AQDELSS----RPQTLP--LPDVVPDGETHLV-----QNGIQLLNGHAPGAVPNLAG----LQQANRHHGL-LGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEJ4-1", "uniprot_id": "Q9VEJ4_DROME", "id": "Q9VEJ4-1", "name": "Ubiquitin-conjugating enzyme E2 J2", "aln": "----------MSSSSTSGGRKQPTAVSRMKQDYMRLKRDPLPYITAEPLPNNILEWHYCVKGPEDSPYYGGYYHGTLLFPREFPFKPPSIYMLTPNGRFKTNTRLCLSISDFHPDTWNPTWCVGTILTGLLSFMLESTPTLGSIESSNYDKQMFAQKSLAFN-LRNTNFCELFPEIVEEIKQRLRGTQAAAAVDGPAANGVKRSNGLANGASLASADGNLAVGGLANPLNAADAIDGGAAGQADLASGGGAAVQNSARNSYLNWQSVYSNLVIIICFAIFALIVNYVIKNLNQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33296-1", "uniprot_id": "UBC6_YEAST", "id": "P33296-1", "name": "Ubiquitin-conjugating enzyme E2 6", "aln": "-------------------MATKQAHKRLTKEYKLMVENPPPYILARPNEDNILEWHYIITGPADTPYKGGQYHGTLTFPSDYPYKPPAIRMITPNGRFKPNTRLCLSMSDYHPDTWNPGWSVSTILNGLLSFMTSDEATTGSITTSDHQKKTLARNSISYNTFQNVRFKLIFPEVVQENVETLE----KRKLDEGDA----ANTGDETEDPFTKAAKEKVIS-----LEEILDPEDRIRAEQALRQS-----ENNSKKDGK--EPNDSSSMVYIGIAIFLFLVGLFMK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:.::* : .:* *** *.* .******* : ** :** ** ***.* ** ::*:***:* *:******* *******::*:******* *.*.***.****** .. .* *** :*:. *: :* :*: :* ::: * :***:*:* : . * . . . : . :. . . : :: :. .: : :* * * .:: ", "identical_positions": 86, "similar_positions": 64, "identity": "29.25%" }, { "cls_id": "homologset.agr.SGD:S000000903", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921W4-1", "uniprot_id": "QORL1_MOUSE", "id": "Q921W4-1", "name": "Ferry endosomal RAB5 effector complex subunit 4", "aln": "MKGLYFQQSSTNEEVTFVFQEK---ENVPVTEDNFVRVQVKACALSHINTKLLA-------------------------------------EMKMEKDFFP-------VGREVSGIVLEVGRKVT-FFQPDDEVVGILPLDSEDPGLCE---VIRVHEHYLVHKPEKVSWTEAAG----VIRDGVRACTALYYLSQLSPGKSVLIMDGASAFGTIAIQLAH--HRGAKVISTAHSLEDKQHLERLRPSIARVIDVSNGKVHVAESCLEETGGLGVDIVIDAGVRLYSKDDEPAVKLHLPHKHDIIT----------LLGVGGHWVTTEENLQ----------LDPPDSHCLFLKGATVAFLNDEVWNLSN--AQQGKYLCILKDVMEKLSAGVFRPLLDEPIPLYEAKVSMEVVQKNQERKKQVVQF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39945-1", "uniprot_id": "AST2_YEAST", "id": "P39945-1", "name": "Protein AST2", "aln": "MAEKILENKDPKLEAMTVDHEVSAPKPIPVDEPTLTRVARPLRHVRHIPVKSLVFHSKHGPITFSYENKIKLPISKNKLVVQVNYVGLNPVDMKIRNGYTKPIYGEAGIGREYSGVITHVGDNLTNRWNVGDDVYGIYYHPKLAIGALQSSLLIDPRVDPILMRPKNTLSPEKAAGSLFCLGTALNLLAQLKEKDQLNTESNVLINGGTSSVGMFAIQLLKRYYKVSKKLVVVTSGNGAAVLSEHFPDLKDEIIFINYLSCRGKSSKPLRRMLDTGKVVDYDDFNTLKETEDYTQGKFNVVLDFIGGYDILSHSSSLIHAKGAYITTVGDYVGNYKKDVFDSWDNPSANARKMFGSMLWSYDYSHFYFDPNIKIIPKKNDWIHECGKLLNEGVVDCVVDKVYSWKNFKEAFSYMATQRAQGKLIMKVEGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :::...: *. * :* : :** * .:.** : ** .* *. :**:.:.: :*** **:: .** ::* :: .*:* ** . * : :* : . :: :*::. .* *. : .:. : * .**.. ..*** .*:*:.* :**** : :: :* : .. * :. *.. *.: * . * .:*. *... *:* . *: * .: :: *:* *: . * ::** : * *.::. : *: : : . : :. * ::: : *. **. ::*: . : * ::. : .:: : * :::. ", "identical_positions": 73, "similar_positions": 129, "identity": "16.98%" }, { "cls_id": "homologset.agr.SGD:S000000904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62241-1", "uniprot_id": "RS8_HUMAN", "id": "P62241-1", "name": "Small ribosomal subunit protein eS8", "aln": "MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEE--ILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62243-1", "uniprot_id": "RS8_RAT", "id": "P62243-1", "name": "Small ribosomal subunit protein eS8", "aln": "MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEE--ILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62242-1", "uniprot_id": "RS8_MOUSE", "id": "P62242-1", "name": "Small ribosomal subunit protein eS8", "aln": "MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEE--ILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62247-1", "uniprot_id": "RS8_DANRE", "id": "P62247-1", "name": "Small ribosomal subunit protein eS8", "aln": "MGISRDNWHKRRRTGGKRKPVHKKRKYELGRPAANTKIGPRRIHTIRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCVVLVDSTPYRQWYESHYALPLGRKKGAKLTPEEEE--ILNKKRSKKVQKKFTLRRKTAKISPLLEEQFLQGKLLACISSRPGQCGRADGYVLEGKELEFYLRKIKAKKGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLY8-1", "uniprot_id": "RS8_DROME", "id": "Q8MLY8-1", "name": "Small ribosomal subunit protein eS8", "aln": "MGISRDSAHKRRATGGKRKSLRKKRKFELGRPAANTKLGSGRVHKVRTRGGNTKLRALRLETGNFAWASEGVARKTRIADVVYNASNNELVRTKTLVKNSIVVIDATPFRQWYEAHYVLPLGRKRNPKHAQKEDENDVLTKKRSEKVMKKYLERQKYGKVEQALEDQFTSGRILACISSRPGQCGRSDGYILEGKELEFYLKKIKSKK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX40-1", "uniprot_id": "RS8B_YEAST", "id": "P0CX40-1", "name": "Small ribosomal subunit protein eS8B", "aln": "MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVK----EEE----TVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******. *** **.** :****:**** .****:*. *:*.:*.****.* ****::.***:*.** ::**** .***:.********:**.* .:* :*:**:***:*:** .**:*:. * *:* . :*:: :*: * .*:. :*.** *:: ***:*****.**.***:***:** ***:::.::* ", "identical_positions": 108, "similar_positions": 60, "identity": "51.43%" }, { "cls_id": "homologset.agr.SGD:S000000905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17156-1", "uniprot_id": "HSP72_MOUSE", "id": "P17156-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "--------------------MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGG-----------------------------GSSGGPTIEEVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14659-1", "uniprot_id": "HSP72_RAT", "id": "P14659-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "--------------------MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGG-----------------------------GSSGGPTIEEVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54652-1", "uniprot_id": "HSP72_HUMAN", "id": "P54652-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "--------------------MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGG----------SG-------------GGGSGASGGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63017-1", "uniprot_id": "HSP7C_MOUSE", "id": "P63017-1", "name": "Heat shock cognate 71 kDa protein", "aln": "---------------------MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMP----------GGMPGGFPG---GGAPPSGGASSGPTIEEVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63018-1", "uniprot_id": "HSP7C_RAT", "id": "P63018-1", "name": "Heat shock cognate 71 kDa protein", "aln": "---------------------MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMP----------GGMPGGFPG---GGAPPSGGASSGPTIEEVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11142-1", "uniprot_id": "HSP7C_HUMAN", "id": "P11142-1", "name": "Heat shock cognate 71 kDa protein", "aln": "---------------------MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMP----------GGMPGGFPG---GGAPPSGGASSGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RCB1-1", "uniprot_id": "M0RCB1_RAT", "id": "M0RCB1-1", "name": "", "aln": "---------------------MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPDEVSSMVLTKMKEIAEAYLGKTVT-----VPAYFNDSQRQAAKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--VRAERNVLIFDLGGGTFDVSILTTEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ-------------------------------KPTLGSSQSPTT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AQL9-1", "uniprot_id": "A0A8I6AQL9_RAT", "id": "A0A8I6AQL9-1", "name": "", "aln": "GGAASVEAMVQLHSWAYTQATMSKEPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNHTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGR-----------------------RPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLEKK--VGAERNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRCLRTACERAKRTLSSSTQTSIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNAKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAIDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTVEKEEFEHQQKELEKVCNPIITKLYQSAG-----------------------------PPGGPDLYTQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q90473-1", "uniprot_id": "HSP7C_DANRE", "id": "Q90473-1", "name": "Heat shock cognate 71 kDa protein", "aln": "---------------------MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVLDANRLNGRQFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYSNDSQRQATKDAGTISGLNVLVIINEPTAAAIAYGLDKK--VGAERNVLIFDLGGGSFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVEDEKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSAGGMP----------GGMPEGMPGGFPGAGAAPGGGSSGPTIEEVD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61696-1", "uniprot_id": "HS71A_MOUSE", "id": "Q61696-1", "name": "Heat shock 70 kDa protein 1A", "aln": "---------------------MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT--GKGERNVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPG----------AGGFGAQAP--------KGASGSGPTIEEVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17879-1", "uniprot_id": "HS71B_MOUSE", "id": "P17879-1", "name": "Heat shock 70 kDa protein 1B", "aln": "---------------------MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT--GKGERNVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPG----------AGGFGAQAPP-------KGASGSGPTIEEVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DMW0-1", "uniprot_id": "HS71A_RAT", "id": "P0DMW0-1", "name": "Heat shock 70 kDa protein 1A", "aln": "---------------------MAKKTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVNYKGENRSFYPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT--GKGERNVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRERVAAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDSNTLAEKEEFVHKREELERVCNPIISGLYQGAGAPG----------AGGFGAQAP--------KGGSGSGPTIEEVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DMV8-1", "uniprot_id": "HS71A_HUMAN", "id": "P0DMV8-1", "name": "Heat shock 70 kDa protein 1A", "aln": "---------------------MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT--GKGERNVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPG----------PGGFGAQGP--------KGGSGSGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DMV9-1", "uniprot_id": "HS71B_HUMAN", "id": "P0DMV9-1", "name": "Heat shock 70 kDa protein 1B", "aln": "---------------------MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT--GKGERNVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPG----------PGGFGAQGP--------KGGSGSGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16627-1", "uniprot_id": "HS71L_MOUSE", "id": "P16627-1", "name": "Heat shock 70 kDa protein 1-like", "aln": "-------------------MAANKGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGHNVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKG--SHGERHVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCNEVLSWLEANQLAEKDEFDHKRKELENMCNPIITKLYQ-SGCTG----------PTCTPGYTP---------GRAATGPTIEEVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55063-1", "uniprot_id": "HS71L_RAT", "id": "P55063-1", "name": "Heat shock 70 kDa protein 1-like", "aln": "-------------------MAANKGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVLVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGHSVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKG--SHGERHVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCSEVLSWLEANQLAEKEEFDHKRKELENMCNPIITKLYQ-SGCTG----------PTCAPGYTP---------GRAATGPTIEEVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34931-1", "uniprot_id": "HS71L_HUMAN", "id": "P34931-1", "name": "Heat shock 70 kDa protein 1-like", "aln": "-------------------MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKG--GQGERHVLIFDLGGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQMCNPIITKLYQ-GGCTG----------PACGTGYVP---------GRPATGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NE33-1", "uniprot_id": "A0A8M1NE33_DANRE", "id": "A0A8M1NE33-1", "name": "Heat shock cognate 71 kDa protein", "aln": "---------------------MAKGLSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDAKRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREIAEAYLGHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKG--RKGERNVLIFDLGGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDAKMDKSQIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMVQDAEKYKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENNQLAEKEEYEHHQKELESVCNPIISRLYQGGAPPA----------GGCGFQAQP----------ESSQGPTIEEVD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11147-1", "uniprot_id": "HSP7D_DROME", "id": "P11147-1", "name": "Heat shock 70 kDa protein cognate 4", "aln": "---------------------MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--AVGERNVLIFDLGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGA--------AGAGGAGPTIEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29843-1", "uniprot_id": "HSP7A_DROME", "id": "P29843-1", "name": "Heat shock 70 kDa protein cognate 1", "aln": "---------------------MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQ--GTSERNVLIFDLGGGTFDVSVLTIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLAERQEFEHKQQELERICSPIITRLYQGAGMAP----------PPTAGGSNP--------GATGGSGPTIEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17066-1", "uniprot_id": "HSP76_HUMAN", "id": "P17066-1", "name": "Heat shock 70 kDa protein 6", "aln": "-------------------MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRR--GAGERNVLIFDLGGGTFDVSVLSIDAG-VFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGGPGVPG----------GSSCGTQAR--------QGDPSTGPIIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "---------------------MSK--AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--SQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGAPG---------AGPVPGAGAG------PTGAPDNGPTVEEVD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9BIS2-1", "uniprot_id": "HSP73_DROME", "id": "Q9BIS2-1", "name": "Major heat shock 70 kDa protein Bb", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGA-------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9BIR7-1", "uniprot_id": "HSP75_DROME", "id": "Q9BIR7-1", "name": "Major heat shock 70 kDa protein Bc", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGA-------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG58-1", "uniprot_id": "HSP74_DROME", "id": "Q9VG58-1", "name": "Major heat shock 70 kDa protein Bbb", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKDERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGA-------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INI8-1", "uniprot_id": "HSP72_DROME", "id": "Q8INI8-1", "name": "Major heat shock 70 kDa protein Ba", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVYNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELARHCSPIMTKMHQQGAGA-------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P82910-1", "uniprot_id": "HSP70_DROME", "id": "P82910-1", "name": "Heat shock 70 kDa protein Aa", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAG------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02825-1", "uniprot_id": "HSP71_DROME", "id": "P02825-1", "name": "Heat shock 70 kDa protein Ab", "aln": "------------------------MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAG------AGGPGANCGQQAGG--------FGGYSGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O97125-1", "uniprot_id": "HSP68_DROME", "id": "O97125-1", "name": "Heat shock protein 68", "aln": "------------------------MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEKYAEEDERHRQRIAARNQLETYLFGVKEAA-ENG-GDRISAADKSSIVERCSEAMKWLDSNTTAEKEEYEYKLKELEQFCSPIMTKMHKGGGDG---------QQAPNFGQQAG-----------GYKGPTVEEVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11146-1", "uniprot_id": "HSP7B_DROME", "id": "P11146-1", "name": "Heat shock 70 kDa protein cognate 2", "aln": "---------------------MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAV-DDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGK------------SSMGKGSH---------------PTVEEVDG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::***********. : .:***:******:********.::***:**.**.*.*:*. ::::**:** ** :* : * ::. : * *:*:***:* *::* ** :** : **** *******:**** *:*:*** *********:****:: *::*********:****:*: : * :***::*************.*:*..: **:** .*: * *::* ****.**********:::.:***:*.** ***:.::******* :***.*::** : * *:*:** *.::***********:* *:.: * .: * *************:***:* * . :*:**:**:*****:*****:*: *: ** ** *: : *:**:*** .* :**:****: *:*** ** *:*:.:********:::*:**::*:**:.*.* : .*.: :.***.*******: ::::*: :** : *: . : : ::* :*:: : : :: . : .: . . **: . .. :*: : .* . **:: :: . ", "identical_positions": 291, "similar_positions": 170, "identity": "42.54%" }, { "cls_id": "homologset.agr.SGD:S000000907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P88-1", "uniprot_id": "NU155_MOUSE", "id": "Q99P88-1", "name": "Nuclear pore complex protein Nup155", "aln": "--------------------------------------MP-SVLGSMMVASTSAAASLQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNSPTVSGMSDMDYP-LQGPGLLSVPSLPEISTIRR---VPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSMCGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED---------------DPIVQIEIDNSRNILYTRSEKGVIQVYDLGHD-GQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIESSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFH--KLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPATLPTPSN--VGPILG-SPMYSSSPVPSGSPYPNPSSLGTPSHGAQPPTMSTPMCAVGSPAMQAASMSGLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPVQLLESVLQELKGLQEFLDRNSQFSGGPLGNPNTTARVQQRLVGFMRPENGNTQQMQQELQRKFQEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFSV--IVGELQKEFQEQLKITTFKDLVIRDKEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKTERE--RMLRESLKEYQKISN---QVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMARVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQ-RQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLAVIHCAGYSDPILVHTLWQDIIEKELNDSVALSSSDR----MHALSLKLVLLGKIYAGTPRFFPLDFIV-QFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37199-1", "uniprot_id": "NU155_RAT", "id": "P37199-1", "name": "Nuclear pore complex protein Nup155", "aln": "--------------------------------------MP-SMLGSMMVASTSAPS-LQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNSPTVSGMSDMDYP-LQGPGLLSVPSLPEISTIRR---VPLRLSWLNSLDTCSVTAMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSVCGGLQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED---------------DPIVQIEIDNSRNILYTRSEKGVIQVYDLGHD-GQGMSRVASVSQNAIVCAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFH--KLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPATLPTPSN--VGPILG-SPMYSSSPVPTGSPYPNPSSLGTPSHGAQPPTMSTPMSAVGNPAMQAASLSGLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPIQLLESVLQELKGLQEFLDRNSQFSGGPLGNPNTTAKVQQRLLGVMRPENGNTQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTV--IVGELQKEFQEQLKITTFKDLVIREKEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKSERE--RMLRESLKEYQKISN---QVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQ-RQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVHTLWQDIIEKELSDSVTLSSSDR----MHALSLKLVLLGKIYAGTPRFFPLDFIV-QFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75694-1", "uniprot_id": "NU155_HUMAN", "id": "O75694-1", "name": "Nuclear pore complex protein Nup155", "aln": "--------------------------------------MPSSLLGAAMPASTSAAA-LQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNNPTVSGMSDMDYP-LQGPGLLSVPNLPEISSIRR---VPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED---------------DPILQIAIDNSRNILYTRSEKGVIQVYDLGQD-GQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFH--KLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSN--VGPILG-SPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTI--IVAELQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKE--RMLRESLKEYQKISN---QVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQ-RQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDR----MHALSLKIVLLGKIYAGTPRFFPLDFIV-QFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V463-1", "uniprot_id": "NU154_DROME", "id": "Q9V463-1", "name": "Nuclear pore complex protein Nup154", "aln": "---------------------------------------------------MTLPQAQLDFFTTATSMLEWHYNLERNKPGLLELTGVS--------------QHGRATMSGLNDYDYQSLSFLKSDRTHNLQQMRTVTK---SAIPNEILEHFKHIKCHCTMGLFPEIGRAWLTIDSEIYIWTFNQTRDVAYYDGLSHLIVSVGLVKPKPGVFVQDVKYLLVLTTPIEVIVLGVTFG----------ESSYNEMQLMNRPVFVIGTDNVSISVIKGTDDGRIFLGGRDG--CLYEIYYQAESSWFGKRCKKINLSQGLVSYMVPSFLK-VFSEV---------------DPIEHIEIDNSRKLLYVLTEKGVIEAWDISTS-YTTARRLGRITQNDITNQAVSLITTVDPSIFKSVKAICPLSADDADKLHLVAVTQCGVRLFFSTTSLNVKQQFGPAVPCSPGENTGFGQPAVQPPLSPNAEAPKGLYLLHVRLPPGYTPNATTNKPKQVHAAHYTEGTMLMITTQQHEQDLLWSLSSAPSVNFTYLVESTALESLDGVVWGLAEVHEPSTPQRKSPLN---------------SARHARKVALLTNQGTHIIE--VLKMVDVLRQILLSCNGPHHEEVKMFFQSQNQREACVTALLLATSDTYRGSDVALWAAQAFMLYGGEPCYQHQKFLNASNRNMANQTLGPNTTNVRERQSMFMSTPMPNSVANSPVGFPGSQFNQPISPIGNMQPPQVAVSNEN-SPIVFSAKHDGLYMYVSRMLHSVWQMRCVNEQFCSN--------LSQSECALLLSDLRSLRSFLEVHSVHDISSTTRVSFDNHLDRTNSYNTIMMG----NTLLPIPEQRVLSEQAQVEETRSLSALNLFVKHACEVISLWNILNSHSFQL--ICVQLSPEHQKLLTCSTFRDLLITRSEVCAFLIISLINLYLKDAAGVSEVSKNLRENCPNLYRHEDDVTYKATELLMNAKNCTSATEKE--HMLRTTLHMCKEAAP---TLPLHSICMQFISADFFEGVIELSAVCASKSDPEEVGVHFYNNGEPADDREGYTCFATRMAYYKEVQLMLDHIYQR---VCNKTHVQDKSINPLKGTAKASDAKNGATQTIPKIVAHTLKVKDPLIHITLYEWLLAHDMLKELLDVVEPSLGEFLRRSVSQNVDNVVLIDLLWKYYEKNSHHSQAAHILDNLAMTRSENINLEQRIEYLVRAVMCMRNGNVGSSLSN-GIFLKELEDKLDIARVQKSVLAAMT-ELASDKLEAATAVKELNYALYDITQLYQHFAEPFDLWECQLSILNCSHHNDPLLIESVWGQIINSVVDK--PGTTSER----CNRLFTKIEILVREYGESGVCFPFAFLI-RELEVKACQLRFPEGIVPEKLVSMNLDIELLLEYYSRMISMNERVWANEGNEWHLIQSVIRVVSLLADNAQSIWYRSKRRIVGKAQDIVAGCLNICYQKPD---TNRLQHSLKELQSQLQRLLI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40064-1", "uniprot_id": "NU157_YEAST", "id": "P40064-1", "name": "Nucleoporin NUP157", "aln": "MYSTPLKKRIDYDRETFTASASLGGNRLRNRPRDDQNNGKPNLSSRSFLSERKTRKDVLNKYGEAGNTIESELRDVTTHVKISGLTSSEPLQLASEFVQDLSFRDRNTPILDNPDYYSKGLDYNFSDEVGGLGAFTPFQRQQVTNIPDEVLSQVSNTEIKSDMGIFLELNYCWITSDNKLILWNINNSSEYHCIDEIEHTILKVKLVKPSPNTFVSSVENLLIVATLFDIYILTISFN-----------DRTHELNIFNTGLKVNVTGFNVSNIISYERTGQIFFTGATDGVNVWELQYNCSENLFNSKSNKICLTKSNLANLLPTKLIPSIPGGKLIQKVLEGDAGTEEETISQLEVDQSRGVLHTLSTKSIVRSYLITSNGLVGPVLIDAAHIRRGMNALGVKNSPLLSNRAFKIAKIVSISMCENNDLFLAVITTTGVRLYFKGS--------------------------------ISRRSIGSLKLDSVKFPPTSISSSLEQNKSFIIGHHPLNTHDTGPLSTQKASSTYINTTCASTIISPGIYFTCVRKRANSGELSKGITNKALLENKE----------------EHKLYVSAPDYGILKNYGKYVENTALLDTTDEIKEIVPLTRSFNYTSTPQGYANVFASQYSAEPLKVAVLTSNALEIYCYRTPDEVFESLIENPLPFIHSYGLSEACSTALYLACKFNKSEHIKSSALAFFSAGIPGVVEIKPKSSRESGSVPPISQNLFDKSGE----CDGIVLSPRFYGSALLITRLFSQIWEERVFVFKRASKT-EKMDAFGISITRPQVEYYLSSISVLADFFNIHRPSFVSFVPPKGSNAITAS------------------DAESIAMNALILLINSIKDALSLINVFYEDIDAFKSLLNTLMGAGGVYDSKTREYFFDLKFHDLFTPNAKTKQLIKEILIEVVNANIASGTSADYIVNVLKERFGSFCHSADILCYRAGEHLEAAQKFEMIDSKISRNHLDTAIDLYERCAENIELCELRRVVDIMVKLNYQPKTVGFLLRFADKIDKGNQAQEYVSRGCNTAD--------PRKVFYDKRINVYTLIFEIVKSVDDYTSIEQSP------SIANISIFSPASSLKKRVYSVIMNSNNRFFHYCFYDWLVANKRQDYLLRLDSQFVLPYLKERAEKS---LEISNLLWFYLFKEEHFLEAADVLYALASS-DFDLKLSERIECLARANGLCDSSTSFDQKPALVQLSENIHELFDIASIQDDLLNLVRNETRIDEDYRKQLTLKLNGRVLPLSDLFNDCADPLDYYEIKLRIFKVSQFKDEKVIQGEWNRLLDSMKNAPSPDVGSVGQESFLSSISNTLIRIGKTTRDTDVVFPVHFLMNKILESFIDKSSAADGSVCSMFLLAGVSHLKLYYILSRIIENSE-----GNVELAKKEMVWLIKDWYQSDSDLRGSIAPEQIKKLEKYDPN--------------TDPVQDYVKDRHHGLK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :: . . : * . ..: . * *. . .* : .. : : . :. . . . **:* :. .*:* *..: :*. :: : * :.. *: * ****... * *. **:::* .:: :* ::: . :::: : *. *. *:**: * . ::*: *:.. . *..:..** ::. :: ::*: * :. :.* :: :*:** :*:. : *.::. : : . : . .: . : * :. : . * .:* ****:*. * * *::** ..: :: . : : : :. .. . . : : :. . . .: : . . :*. *. : . * .* ::.:: . . . : : .. * :* : . :. .: * . .. . *. . . . .. . . . .: .:.. ** * :. * : .:*:: .:*: . : .. . : * .: : :. . : : . . . : . :* : *:. ::. : : :: * . : : . * *. : .:: :: .::* : . :... : *:: : * : :* * * ::: .: . * ::. :. : * : . : .: : *.* * . .: ..* * * *. : : . : . : ... : . * :: . :: :: :*:**: . . ** : . : .* . . . : :*** * *: . .** :* ** . ::.*.:*:* :.** ... .. . : .::.: :::* :* .: : . .. :*: : ::.*: . *:*:. * :* ::: : ..* ::. * :::. . . * : .: : : : **. *:: : ** * * . : .: * .:::. : : : : .:.. .:: .: : .*. : *: ", "identical_positions": 135, "similar_positions": 415, "identity": "8.92%" }, { "cls_id": "homologset.agr.SGD:S000000909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3SWS8-1", "uniprot_id": "RAE1L_RAT", "id": "Q3SWS8-1", "name": "mRNA export factor", "aln": "MSLFGTTSGFGTGGTSMFGSTTTDNHNP--MKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHDAPVKTIHWIKAP--NYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQD----IYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPVAACGFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRN-AAEELKPRNKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C570-1", "uniprot_id": "RAE1L_MOUSE", "id": "Q8C570-1", "name": "mRNA export factor", "aln": "MSLFGSTSGFGTGGTSMFGSTTTDNHNP--MKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHDAPVKTIHWIKAP--NYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQD----IYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPIAACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRN-AAEELKPRNKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78406-1", "uniprot_id": "RAE1L_HUMAN", "id": "P78406-1", "name": "mRNA export factor RAE1", "aln": "MSLFGTTSGFGTSGTSMFGSATTDNHNP--MKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAP--NYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQD----IYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRN-AAEELKPRNKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWF0-1", "uniprot_id": "RAE1L_DANRE", "id": "Q7ZWF0-1", "name": "mRNA export factor", "aln": "MSLFGTNTGFGSGGTGVFGSTTTDSHNP--MKDVEVTSPPDDSISCLAFSPPTMPGNFLIGGSWANDVRCWEVQDNGQTVPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHEGPIRTIHWIKAP--NYSCIMTGSWDKTLKFWDTRSPNPMMSLQMPERCYCADVVYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQSKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTATPQD----IYAVNAISFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPITACCFNHNGNIFAYASSYDWSKGHEYYNPQKKNYIFLRN-AAEELKPRNKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2E7-1", "uniprot_id": "RAE1_DROME", "id": "Q9W2E7-1", "name": "Protein Rae1", "aln": "----------------MFG--ATQSTNR--MNDFEVASPPDDSVSALEFSPSTVQKNFLVAGSWDSTVRCWEVEQNGATVPKSMKTMGGPVLDVCWSDDGSKVFVASCDKQVKLWDLASDQVMQVAAHDGPVKTCHMVKGP--TYTCLMTGSWDKTLKFWDTRSPNPMMTINLPERCYCADVEYPMAVVGTANRGLIIYSLQNSPTEYKRQESPLKYQHRAISIFRDKKKEPTGCALGSIEGRVAIQYVNPGNP-KDNFTFKCHRTTG--TSGYQD----IYAVNDIAFHPVHGTLVTVGSDGTFSFWDKDARTKLKSSETMDQSITKCGFNANGQIFAYAVGYDWSKGHEYFNPAKKPQIFLRS-CYDELKPRIN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40066-1", "uniprot_id": "GLE2_YEAST", "id": "P40066-1", "name": "mRNA export factor GLE2", "aln": "MSFFNRSN-----TTSALGTSTAMANEKDLANDIVINSPAEDSISDIAFSP--QQDFMFSASSWDGKVRIWDVQN-GVPQGRAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQTQQIGMHSAPIKVLRFVQCGPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYN----EADGYAIGSVEGRCSIRYIDDGMQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1T0-1", "uniprot_id": "Q9W1T0_DROME", "id": "Q9W1T0-1", "name": "", "aln": "--------------MNQFGQPKQTQQQD-----YELPNPPNDTISALEFSPRSSSWNAICAGSWDNTVRIWEVQADRLVP-KVMNSLEGTPFDVTWNDSGNKVYLSDSSGQVTEWDLESNQLRKVGLHARAARTCHWVGPY------LATTSWDKSIRFWDPRAAIELTRMELPDRSYAADVLNDVAVVACGDRSILAYTLRGGPVEQGRMKSPGESNTQVRSVALHQNRDLTSWLIAKTNG---MVFDQSMAHRTVSFPIRCHRREN---SGILD----VYAVNEVKVNMVTQHIATVGSDGVFCFWDSQMRSKLLESKVHPQPITKCAISGDGKLFAYALGYDWSKGHEYSDSSIKPHIFLRPFETNVAA-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : ...:*::. : *** : ..** . ** *:*: : : .. : . *.:.*.** .... . :*: *.* ::. * . :. : : : * ****::::** * . : : :*:* *. * : **. .:* : * . . ** : : : : . . :.. :* : : : . .*.::*** . : : :*.** : .: : :.*.*.** * ***.: * :* .:. * :. :*.:**** .*** :** . * *: : ", "identical_positions": 68, "similar_positions": 108, "identity": "18.04%" }, { "cls_id": "homologset.agr.SGD:S000000912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2D7-1", "uniprot_id": "D4A2D7_RAT", "id": "D4A2D7-1", "name": "", "aln": "MEPAGLEQILKELLMPDTER-IRRATEQLQTALR-DPAALPALCDLLASATDPQIRQFAAVLTRRRLSNR--WRRLAPEQRESLKSLVLTALQKETEHYVSVSLAQLSATIFRKEGLQG---WPQFMNLLQHSTHSAHSPEKEVGLLLLSVVVSSQPEAFHAHQQELLQLLIETLSEVSFPG-----VLFYSLRTLTALARYLR--PDDVSLARMLVPKVVTALRTLIP-LDEVKACEALEALDEMLETELPIITPHLSEVLTFCLEVAKNVALGEAIRVRILCCLTFLVKVKSKALLKNRLLPPLLNALFPIMAAEPPLGQLDPEDQDSDDDDLEIGLMGETPKHFAVQVVDMLALHLPPEKLCPHVMPMLEEALRSEAPYQRKAGFLVLAVLSDGAGDHIRQRLLYPLLQIVCKGLDDPSQVVRNAALFALGQFSENLQPHISSYSEEVMPLLLTYLKSVPMG------NTHHLAKACYALENFVENLG-PKVQPYLPELMECMLQPLKNPSKARTKELAVSAIGAIATAAQDSLLPYFPTVMEHIREFLL-----TGH-DDLHLVQIQSLETLGVLARALG-ESMKPLAEECCQLGLGLCIH-VDDPDVRRCTYSLFAALSGLMGESLGPYLPQITTLMLLSLRSTEGIVPQYDGISSFLLFEDDSEAEEEEELMDEDMEEEEDDSEISGYSVENAFFDEKEDTCTALGEISMNTSVAFLPFMDAIFDEVYKLLECPHMNVRKAAYEALGQFCCALHKACQRGPSDPNN-AALQSSLARAIPSYMQAVKV--------ERERPVVMAVLEALTGVLRTCGALTLQPPG---RLSELCNVLKAVLQKKTACQDAEED---DDE-DDDQAEYDAMLLEHAGEAIPVLAAAAGGHAFAPFFA---TFLPLLLCKTKQSCTVAEKSFAVGTLAESIQGLGAASAQFVSRLFPVLLNNAREADPEVRSNAIFGLGVLAEHGGCPAQDHFPKLLGLLLPLL---------------ARERHDRVRDNICGALARLLMASPAGKTEPQVLATLLHALPLKEDMEEWVTIGHLFSFLHQNNPDQVVGVASELLRICSLILPDN----RIPPDTKAALLLLLTFLAKQHSDSFHTALGSLPDDKARELQAMLGLT--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI75-1", "uniprot_id": "IPO4_MOUSE", "id": "Q8VI75-1", "name": "Importin-4", "aln": "MEPAGLEQILKELLLPDTER-IRRATEQLQTILR-DPAALPALFDLLATATDSQIRQFAAVLTRRRLNNR--WRRLAPEQRESLKSLVLTALQKETVHSVSVSLAQLSATIFRKEGLQG---WPQFMNLLQHSTHSSHSPEKEVGLLLLSVVVSSQPEAFHAHQHELLQLLNETLSDVSFPG-----VLFYSLRTLTAIARYVR--PDDVSLARMLVPKVVTALRTLIP-LDEVKACEALEALDEMLETELPIINPHLSEVLTFCLEVAKNVALGEPLRVRVLCCLTFLVKVKSKALLKNRLVPPLLHALFPLMAAEPPMGQLDPEDQDSDDDDLEIGLMGETPKHFAVQVVDMLALHLPPEKLCPHVMPMLEEALRSEDPYQRKAGFLVLAVLSDGAGDHIRQRLLYPLLQIVCKGLDDPSQIVRNAALFALGQFSENLQPHISSYSEEVMPLLLSYLKSVPMG------NTHHLAKACYALENFVENLG-PKVQPYLPELMECMLQPLKNPSKARTKELAVSAIGAIATAAQDSLLPYFPTIMDLLREFLL-----TGH-EDFHLVQIQSLETLGVLARALG-ESMKPLAEECCQLGLGLCIH-IDDPDVRRCTYSLFAALSGLMGEGLGPYLPQITTLMLLSLRSTEGIVPQYDGISSFLLFDDDSEAEEEEELMDEDMEEEGDDSEISGYSVENAFFDEKEDTCTALGEISMNTCVAFLPFMDATFDEVYKLLECPHMNVRKSAYEALGQFCCALHKASQRSSSDPSSSPVLQTSLARVMPAYMQAVKV--------ERERPVVMAVLESLTGVLRTCGSLALQPPG---RLSELCNVLKAVLQKKTACQDAEED---DDE-DDDQAEYDAMLLEHAGEAIPVLAATAGGHAFAPFFA---TFLPLLLCKTKQSCTVAEKSFAVGTLAESIQGLGTASAQFVSRLFPVLLNNAREADPEVRSNAIFGLGVLAEHGGCPAQDHFPKLLGLLLPLL---------------ARERHDRVRDNICGALARVLMASPVGKTEPQVLATLLRALPLKEDMEEWLTIGHLFSFLHQNNPEQVVDVASELLRICSLILPDN----RIPPDTKAALLLLLTFLAKQHTDSFHTALGSLPNDKAQELQAMMGLT--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEX9-1", "uniprot_id": "IPO4_HUMAN", "id": "Q8TEX9-1", "name": "Importin-4", "aln": "MESAGLEQLLRELLLPDTER-IRRATEQLQIVLR-APAALPALCDLLASAADPQIRQFAAVLTRRRLNTR--WRRLAAEQRESLKSLILTALQRETEHCVSLSLAQLSATIFRKEGLEA---WPQLLQLLQHSTHSPHSPEREMGLLLLSVVVTSRPEAFQPHHRELLRLLNETLGEVGSPG-----LLFYSLRTLTTMAPYLS--TEDVPLARMLVPKLIMAMQTLIP-IDEAKACEALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLTFLVKVKSKALLKNRLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHFAVQVVDMLALHLPPEKLCPQLMPMLEEALRSESPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQIVCKGLEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLLLAYLKSVPLG------HTHHLAKACYALENFVENLG-PKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLPYFPAIMEHLREFLL-----TGR-EDLQPVQIQSLETLGVLARAVG-EPMRPLAEECCQLGLGLCDQ-VDDPDLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEGIVPQYDGSSSFLLFDDESDGEEEEELMDEDVEEE-DDSEISGYSVENAFFDEKEDTCAAVGEISVNTSVAFLPYMESVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPNT-AALQAALARVVPSYMQAVNR--------ERERQVVMAVLEALTGVLRSCGTLTLKPPG---RLAELCGVLKAVLQRKTACQDTDEE---EEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPFFA---GFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLPVLLSTAQEADPEVRSNAIFGMGVLAEHGGHPAQEHFPKLLGLLFPLL---------------ARERHDRVRDNICGALARLLMASPTRKPEPQVLAALLHALPLKEDLEEWVTIGRLFSFLYQSSPDQVIDVAPELLRICSLILADN----KIPPDTKAALLLLLTFLAKQHTDSFQAALGSLPVDKAQELQAVLGLS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PFR8-1", "uniprot_id": "M9PFR8_DROME", "id": "M9PFR8-1", "name": "", "aln": "-MEAAILDIINGILAIDTER-IRESTAKMLKAYE-NPDSLLVLTQIVMSDRPVQERQVAAVLLKRRVKKLRHWQLVPAEHQAAIKSNMLQVLIAVKEKTVKGTVAFIIGSLVRHEEDKQNSWREEILKFIYERCSSPDPIESERGSSIFSSLMDAAPDQFSNHTDTIFPLLAGILVTAEANGNMATPTVHNMLAGTCVLLPFISGHSDAEQIMVKAVPLILKALAAFAEKGNSNEFMGAFDIIDSMAEYVPHLLTGNVKLLLEFCLMIARNKQFDASIRVQVLTFVGSLVRLKKKIIMKQKLLQPTLSVLFEVICQD---------DLKEGDDDYFSSESLNSPSNAAAQTLDLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLNIIKAGVLDSVMFVRTAAFFALGQFSEFLQPTICKFAPQILPVLFDYLNQLVLELKVGEPDSKHMDRMFYALETFCENLD-EDIVPYLPTLMDRLFGVMEPQNSNQMREMALSAIAAVSAAAKENLMPYFPRIMTVLQGCLV-----KDCPKEMYSQRIQAIDTLAALCRELGKDNIIPLADETMNFCLMMLEDGPDDPEFRRSIYNLMSSLSSVVNESMASVFPKFIDRIMESVISSEDMVPNVSDN------AEDDLALVDAPDIEIDLEHTDDEDDQDAYLGENDYIVEKEEAILSLKEFATHTGAAFAPYLQSAFENVYKMIDHPQGDVRMACIDSICSFITALHKLDDAAG--------LKRACEIAIPKFAHIMRT--------DDQVAVVLRMLDVLYDVFKYVPAINSQE-----HAELIFGCIRDIFTNKMACQFNEESG-GGDDECSEESENDEMLFENAANLFPMFGLTLQPELFSLYFGRLYHFYIQRLAKVKERDLPEQRAYIYGALADCCKALKGCCATYFDALRPIFIAGSRDSDAKARQNSYFALGEIVFHSEEKSFESYPTILQALSEAI---------------VRESVPAAMDNICGAVARLIVTNPDSVPLGQVLPVWLNHLPLKDDTVENDVIQKAFRVLYLKARPSIEAHLEQILAITIEASYKK----QMPDVETTESAVALIKEIRANYPELFSKVSNMNPEVFNYVQAL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7R5-1", "uniprot_id": "Q9I7R5_DROME", "id": "Q9I7R5-1", "name": "", "aln": "-MEAAILDIINGILTIDTER-IRESTAKMLKAYE-NPDSLLVLTQIVMSDRPVQERQVAAVLLKRRVKKLRHWQLVPAEHQAAIKSNMLQVLIAVKEKTVKGTVAFIIGSLVRHEEGEQNSWREEILKFIYERCSSPDPIESERGSSIFSSLMDAAPDQFSDHTDTMFPLLAGILVTAEANGNMATPTVHNMLTGSCFLLPFVSGHSNAEQIVVKAVPLILKALAAFVEKGYSIEFMGAFDIIDSMAEHVPHLLTGNVKLLLEFCLMIARNKQFDASIRVQVLTFVGSLVRLKKKIIMKQKLLQPTLSVLFEVICQD---------DLEEGDDDYFSSESLSSPSNAAAQTLDLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLNIIKAGVLDSVMFVRTAAFFALGQFSEFLQPTICKFAPQILPVLFDYLNQLVLELKVGEPDSKHMDRMFYALETFCENLD-EDIVPYLPTLMDRLFGVMEPQNSNQMREMALSAIAAVSAAAKENLMPYFPRIMTVLQGCLV-----KDCPKEMYSQRIQAIDTLAALCRELGKDNIIPLADDTMNFCLMMLEDGPDDPEYRRSIYNLMSSLSSVVNESMASVFPKFIDRIMESVIFSEDMVPNVSDN------ADDDLALVDAPDIEIDLEHTDDEDDQDAYPVENDYIVEKEEAILSLKEFATHTGAAFAPYLQSAFENVYKMIDHPQGDVRMACIDSICSFITALHKLDDAAG--------LKRACEIAIPKFAHIMRT--------DDQVAVVLRMLDVLYDVFKYVPAINSQE-----HAELIFGCIRDIFTNKMACQFNEESG-GGDDECSEESENDEMLFENAANLFPMFGLTLQPELFSLYFGRLYHFYIQRLAKVKERDLPEQRAYIYGALADCCKALKGCCATYFDALRPIFIAGSRDSDAKARQNSYFALGEIVFHSEEKSFESYPTILQALSEAI---------------VRESVPAAMDNICGAVARLIVTNPDSVPLGQVLPVWLNHLPLKDDTVENDVIQKAFRVLYLKARPSIEAHLEQILAITIEASYKR----QMPDVETTESAVALIKEIRANYPELFSKVSNMNPEVFNYVQAL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40069-1", "uniprot_id": "IMB4_YEAST", "id": "P40069-1", "name": "Importin subunit beta-4", "aln": "MDQQFLSQLEQTLHAITSGVGLKEATKTLQTQFYTQPTTLPALIHILQNGSDDSLKQLAGVEARKLVSKH--WNAIDESTRASIKTSLLQTAFSEPKENVRHSNARVIASIGTEELDGNK--WPDLVPNLIQTASGEDVQTRQTAIFILFSLLEDFTSSLSGHIDDFLALFSQTINDPSSLEIR-SLSAQALNHVSALIEEQETINPVQAQKFAASIPSVVNVLDAVIKADDTMNAKLIFNCLNDFLLLDSQLTGNFIVDLIKLSLQIAVNSEIDEDVRVFALQFIISSLSYRKSKVSQSKLGPEITVAALKVACEEID------VDDELNNEDETGENEENTPSSSAIRLLAFASSELPPSQVASVIVEHIPAMLQSANVFERRAILLAISVAVTGSPDYILSQFDKIIPATIN-GLKDTEPIVKLAALKCIHQLTTDLQDEVAKFHEEYLPLIIDIIDS--------AKNIVIYNYATVALDGLLEFIAYDAIAKYLDPLMNKLFYMLESNESSKLRCAVVSAIGSAAFAAGSAFIPYFKTSVHYLEKFIQNCSQIEGMSEDDIELRANTFENISTMARAVRSDAFAEFAEPLVNSAYEAIKT--DSARLRESGYAFIANLAKVYGENFAPFLKTILPEIFKTLELDEYQFN----------------FDGDAEDLAAFADSANEEELQNKFTVNTGISYEKEVASAALSELALGTKEHFLPYVEQSLKVLNEQVDESYG-LRETALNTIWNVVKSVLLASKVEPESYPKGIPASSYVNADVLAVIQAARETSMGNLSDEFETSMVITVMEDFANMIKQFGAIIIMDNGDSSMLEALCMQVLSVLKGTHTCQTIDIEEDVPRDEELDASETEATLQDVALEVLVSLSQALAGDFAKVFDN-----FRPVVFGLFQSKSKNKRSSAVGAASELALGMKEQNPFVHEMLEALVIRLTSDKSLEVRGNAAYGVGLLCEYASMDISAVYEPVLKALYELLSAADQKALAAEDDEATREIIDRAYANASGCVARMALKNSALVPLEQTVPALLAHLPLNTGFEEYNPIFELIMKLYQENSPVITNETPRIIEIFSAVFTKENDRIKLEKESTLGREENMERLKQFQTEEMKHKVIELLKYLNTTYNGIVAQNPVLAAVIA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . : : ::.:* : * :* .* .:: . . :*.*.* :: :.. *. : . : ::*: :* . . * : * : .:: .* ::: : . . . : . :: :: .. : * :: *: : : . :* :: .: :. : :: ::.: : : :: :.* :* * :. :*: * : : :.. : :.:* . : : . : * . ::: .:*. * : : : : .: *.:. . :: : *:* *:: :: :.* *. : * .: : : *: *. .*: **: .: *:: ** :..: : :*::: :.. . **: : * : : ** **: :: :. .. : : .:**:.: : ** ::*** : :. : . .: : ::::.:..:.* : : : :*: : *.. *.. * ::: *: : .*.:.. : : :: :: * . : : : ::. . : :. *** : :: *:: * * *::: :. : : :: . :* :. ::: .. :: . . : : . : : :*: ::: : .::: :: : : :: . :** : . : : :* : * : * : : :. : . : : : ::: *: :: .: . . * .:.: : : . :.* *: :.:* : :. : :* * : .** . * .*.:**: : .. . *.:.. * ***: . * * . : *: . : .:: * .. :: . : : : .: : .: :.: ", "identical_positions": 99, "similar_positions": 369, "identity": "8.56%" }, { "cls_id": "homologset.agr.SGD:S000000914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4Z0-1", "uniprot_id": "LSM4_HUMAN", "id": "Q9Y4Z0-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVKEEVV------AKGRG-------RGGLQQQKQQKGRGMGGAGRGVFGGRGRGGIPGTGRGQPEK------------KPGRQAGKQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXA5-1", "uniprot_id": "LSM4_MOUSE", "id": "Q9QXA5-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVREEA-------AKGRG-------RGGPQQ-KQQKGRGMGGAGRGVFGGRGRGGIPGAGRGQPEK------------KPGRQAGKQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6APJ0-1", "uniprot_id": "A0A8I6APJ0_RAT", "id": "A0A8I6APJ0-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "-LPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVREEA-------AKGRG-------RGGPQQQKQQKGRGMGGAGRGRVTMRG-GRQASSEQSQPEL------------SPGRWVRRPPGAFA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VKW8-1", "uniprot_id": "Q9VKW8_DROME", "id": "Q9VKW8-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQSHPMLVELKNGETYNGHLVSCDSWMNINLRDVICTSKD----------GDRFWRMPECYIRGSTIKYLRIPDEVIDMVKEDAQ------AKSRNRTEMNKNRGGNSSQNQRGGR-PGGGNRNNVGNRPGQGYGGAANNAMRLGG----------AAGQGNRLPHAAKNRK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40070-1", "uniprot_id": "LSM4_YEAST", "id": "P40070-1", "name": "LSM complex subunit LSM4", "aln": "MLPLYLLTNAKGQQMQIELKNGEIIQGILTNVDNWMNLTLSNVTEYSEESAINSEDNAESSKAVKLNEIYIRGTFIKFIKLQDNIIDKVKQQINSNNNSNSNGPGHKRYYNNRDSNNNRGNYNRRNNNNGNSNRRPYSQNRQYNNSNSSNINNSINSINSNNQNMNNGLGGSVQHHFNSSSPQKVEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **..*:.: * :****** :* *.. *.***:.* :* *.: ..: :: * ****: **:::: *::** *::: ::. . *.. .. : * .... . .: . . * ", "identical_positions": 36, "similar_positions": 48, "identity": "19.25%" }, { "cls_id": "homologset.agr.SGD:S000000915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HD45-1", "uniprot_id": "TM9S3_HUMAN", "id": "Q9HD45-1", "name": "Transmembrane 9 superfamily member 3", "aln": "MRPLPGALG------VAAAAALWLLLLLLP-------------RTRADEHEH---TYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPATYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLP--IWGIVGEADE---------------NGEDYYLWTYKKLEIGFNG-----NRIVDVNLTSEGKVKLVPNT--------------------KIQMSYSVKWKKS-DVKFEDRFDKYLDPSFFQH----RIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEE---------MDDMDRDLGDEYGWKQVHGDVFRPSSH----PLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTER-GSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQ------------------MFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNL-------SGQPNFPCRVNAVPRPIPEKKWFMEPAVIV--CLGGILPFGSIFIEMYFIFTSFWAYKI--YYVYGFMMLVLVILCIVTVCVTIVCTYFLL------NAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ET30-1", "uniprot_id": "TM9S3_MOUSE", "id": "Q9ET30-1", "name": "Transmembrane 9 superfamily member 3", "aln": "MRPLPGAPG------VAAAAA--LLLLLLP-------------RARSDEHEH---TYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLP--IWGIVGEADE---------------NGEDYYLWTYKKLEIGFNG-----NRIVDVNLTSEGKVKLVPNT--------------------KIQMSYSVKWKKS-DVKFEDRFDKYLDPSFFQH----RIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEE---------MDDMDRDLGDEYGWKQVHGDVFRPSSH----PLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTER-GSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQ------------------MFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNL-------SGQPNFPCRVNAVPRPIPEKKWFMEPAVIV--CLGGILPFGSIFIEMYFIFTSFWAYKI--YYVYGFMMLVLVILCIVTVCVTIVCTYFLL------NAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUD8-1", "uniprot_id": "D3ZUD8_RAT", "id": "D3ZUD8-1", "name": "Transmembrane 9 superfamily member", "aln": "MRGDPGACQPGNTHHFTAGSDFSLPFSLSPEPDLNRGVGTALGKRRCEQLTRG--QYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLP--IWGIVGEADE---------------NGEDYYLWTYKKLEIGFNG-----NRIVDVNLTSEGKVKLVPNT--------------------KIQMSYSVKWKKS-DVKFEDRFDKYLDPSFFQH----RIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEE---------MDDMDRDLGDEYGWKQVHGDVFRPSSH----PLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTER-GSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQ------------------MFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNL-------SGQPNFPCRVNAVPRPIPEKKWFMEPAVIV--CLGGILPFGSIFIEMYFIFTSFWAYKI--YYVYGFMMLVLVILCIVTVCVTIVCTYFLL------NAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRN1-1", "uniprot_id": "Q9VRN1_DROME", "id": "Q9VRN1-1", "name": "Transmembrane 9 superfamily member", "aln": "MGSSATQTT-------VPFRAICLCLLIAS---------CYVSLSQADEHNH---KYNDREEVVLWMNTVGPYHNRQETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVKNEYWYQMYIDGLP--IWGKVGERDE---------------RDGKYYIFTHKKFDIGYNG-----QQIVDITLTTEGREELKPGS--------------------HINFSYEVNWKPS-KVEFKNRFDKYLDPNFFQH----RIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEE---------IDDMERDLGDEYGWKQVHGDVFRSPPN----TLLFSALVGAGYQLISVVFCVIMFAIVGELYTER-GSMLSTAIFVYAATSPINGYFGGSLYARLGGRMWIRQ------------------MLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTMVAVTCICLFVILPLTLVGTVVGRNL-------DGQPDFPCRVNAVPRPIPEKKWYMEPLIIV--LLGGVLPFGSIFIEMYFIFTSFWAYKI--YYVYGFMLLVFSILTVVTVCVTIVCTYFLL------NAEDYRWQWTSFMAAGSTSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNVKID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DBU0-1", "uniprot_id": "TM9S1_MOUSE", "id": "Q9DBU0-1", "name": "Transmembrane 9 superfamily member 1", "aln": "MTVLGYPRSWSCHCL-----PVLILLLGIG--------------HGPWVEGVT--HYKPGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEK--IRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLP--IRGFVGYMEESGFLP----------HSHKIGLWTHLDFHLEFHG-----DRIIFANVSVRDVKPHSLD--GLRSDELLG-----------LTHTYSVRWSET-SVEHRSDRRRGDDGGFFPRT--LEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETS------SGGSSDDFDQGDNGWKIIHTDVFRFPPY----RGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWN------------------IILTSSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNN-------ASPFDAPCRTKNIAREIPPQPWYKSTVIHM--TVGGFLPFSAISVELYYIFATVWGREQ--YTLYGILFFVFAILLSVGACISIALTYFQL------SGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15321-1", "uniprot_id": "TM9S1_HUMAN", "id": "O15321-1", "name": "Transmembrane 9 superfamily member 1", "aln": "MTVVGNPRSWSCQWL-----PILILLLGTG--------------HGPGVEGVT--HYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEK--IRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLP--IRGFVGYMEESGFLP----------HSHKIGLWTHLDFHLEFHG-----DRIIFANVSVRDVKPHSLD--GLRPDEFLG-----------LTHTYSVRWSET-SVERRSDRRRGDDGGFFPRT--LEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETT------SAGSGDDFDQGDNGWKIIHTDVFRFPPY----RGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWN------------------IILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNN-------ASPFDAPCRTKNIAREIPPQPWYKSTVIHM--TVGGFLPFSAISVELYYIFATVWGREQ--YTLYGILFFVFAILLSVGACISIALTYFQL------SGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IQ52-1", "uniprot_id": "A0AC58IQ52_DANRE", "id": "A0AC58IQ52-1", "name": "Transmembrane 9 superfamily member", "aln": "MPGVVMTARLECLGLRVAGRSVTLCVLVLC--------------LMPYFGWAV--SYKQGDPVVLYVNKVGPYHNPQETYHYYTLPVCRPKE--VRHKALSLGEVLDGDRMAESLYNIRFKENADRLTLCKLTLSEKEVDQLREAIEELYYFEFVLDDIP--IWGFVGYMEESGFLP----------HSHKVGLWTHLDLNIEYNG-----DSVIFANVSVKDVKPEPLEEGGAIHGAGVGSGG------LSITHTYSVRWFET-TLPHSRRAERLRDYSFFPKT--LEIHWLSIINSLVLVVLLLGFVIIILMRVLKNDFARYNVEED----------GGCDDLDQGDNGWKIIHTDVFRFPPY----KSLLCAVLGVGAQFLTLATGIIVMALLGMFNVHRHGAINSAAIVLYALTSCVSGYCSCSFYTQIQGQRWVWN------------------IILTSALFSAPLFFTWSVVNSVHWWSGSTQALPATTVLLLLGAWVLVGFPLTVIGGIVGKNR-------AGNFQAPCRTRNIARQIPQQPWYKHTAVHM--AIGGFLPFSAISVELYYIFATAWGREH--YTLYGILLCVFAILLSVGACISVALTYFLL------SGEDYRWWWRSVLSTGSTGIFIFVYSLFYYHNRSNMSGLVQSVEFFGYSLLTAFVFSLMLGTVSFWASLAFIRYIYRSLKMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40071-1", "uniprot_id": "TMN3_YEAST", "id": "P40071-1", "name": "Transmembrane 9 superfamily member 3", "aln": "MRVRPKRSVITLMAIVVVMLILRNQFYSSRTRGHGQEPVISSSQKNLYDGWITPNFYRKGDPLELIVNKVESDLT-QLPYAYYDLPFTCPPTMHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLCARKTTKEGMQTLDKLVREGYVVQWLIDDELPAATTFISTTDHKKYYASGFPLGFIDPDTDKTYLHNHVMLVIRFHASDNDKNTIVGFEVYPRSVSDYHCPGASKNYEQYEIVIPEDENELTYLPFTYSVYWREEFEVDWNHRWDYFLNAGELSDEQSIQFHWMSLANSVGIVLSISFITLIIYVRVMYTDKSNSKSPKYMINIEGIETEDDLDDDKYGKYSVYTVAKDWIQNGRPNLFGLKVLILLVSFGVQFLFTIIGSLTISCSMNKLHNVRNSVLTMAILFFVLGAFMASFVGTRLSMVTKTKRTKANYLDDNRYLKDYKKFSPIFTILCGSSLPGIVMVSTFLLNSIVWAHDSTSALPFKTIVFFMSIYFIVCIPLSLFGGIVANNIPLPQYWLSGITKDESNSDGNGLFVPKSRAKFNPLVYCGIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFYGFLFLSIILLCVLTMEISIIGSYLLMRFCFEDKVVRNNWRWKCFEMGFSGGVYMELYSLYYIFAVLNIHGFSSILISICYSLIFNVMCSLGLGALSYLTASWFINKIYHQKVNL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *. : : * :*.* . . * .* *: **. :*.* : * . * .:.* .: * . . : :.: * : :*. :. :. . : .: : : ::. : :: : .. : :*.* * : : . : .:**:*: **. :*. : :. :* :*.: .* :. . : .. : .. . : * :: :: ::. * *:: : .: . .:: : **..:. . : .: . : . : :: .. . : .:* : :: *:* *:: . .:* :**.:.* :...* . . .. :* . . : : *.:*: * :*: ::: : * : * .**::: : :* : ::: :*: : . .* * .. * .::: **.:* :: * . : * : : *::.: : *:. ** . ", "identical_positions": 67, "similar_positions": 191, "identity": "9.48%" }, { "cls_id": "homologset.agr.SGD:S000000916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WWN9-1", "uniprot_id": "ICEF1_HUMAN", "id": "Q8WWN9-1", "name": "Interactor protein for cytohesin exchange factors 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRR-------------------ISCKDLGHADCQGWLYKKKE-----------------KGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADG-------FVNLPDFTV---------------------------ERASECKKKHAFKISHP------------QIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPP----------------PPHASQTQSLTAQQASSSSPSLSGTSYS---------------------------FSSLENTVKTPSSFP------------------------------------------------------SSLSKERQSLPDTVNSLS---------------------AAEDEGQ--PITFAVQVHSPVPSEAGIHKALENSFVTSESG-----------FLNSLSSDDTSSLSSNHDHLT-VPDKPAGSKIMDKEETKVSEDDEMEKLYKSLEQASLSPLGDR------------------------RPSTKKELRKSFVKRCKNPSINEKLH-----------------------------KIRTLNSTLKCKEHDLAMIN----------------------------------------------------------------------------------------QLLDDPKLTARKYREWKVMNTLLIQD-------IYQQQRASPAPDDTDDTPQELKKSPSSP---SVENSI------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39969-1", "uniprot_id": "BOI2_YEAST", "id": "P39969-1", "name": "BEM1-interacting protein 2", "aln": "MSNDREVPTLSQLNTTVSRDKDVSDTLSPDFDSKGSATGRDGGNFPMYIAINEYFKRMEDELDMKPGDKIKVITDDEEYKDGWYFGRNLRTNEEGLYPVVFTQKITVEKAPTLMRAKSTKRIYSPLTNEDPLLSSTFISENDSNSELPTPQPIETAASISRTANGKIERNLSLKNTMSDIDNALLEFKDDSIGPPDRFINSGRDEEHSITHETILSATDGLDVVESNSKPTTSSSTGFLNGDLENQATLINGIDTTKLNPVEAEFWSPEEITAYFIMEGYDVQSASRFQKHKISGKILLELELVHLKELDINSFGTRFEIFKEIEKIKEAIRTNGRSLNRASKTNNANIYNQLMPPANVDQRASYRGHVRKTSQSLEDLPSQQNFIPTPRNTRNSSASKHRPKSLVFDSQEANANIAPDVQIPQVVEEMAGNENLFVSPRRAPKPPSYPSPAQPPKSPLLNNTRTSPSPAQLYSWQSPTLSFSGPKRTSYIDQYSSSDSNFNSRSALPKNNQGGGKALSPIPSPTRNSVRNEDSEGKLTSSSKRNSVPYYGYAPESSSDRKSSCSSHEEEQFQETMNTFERPTSSIYADGSTIASISNDKLAHEKEGKKKPTRHSSSLSSKSKSDSRRNSSLKRSSSASRTSSFKKSSFMLSPFRQQFTDNAARSSSPEENPITSMPSEKNSSPIVDKKSSKKSRSKRRSVSAKEAEIFTETVKDDKNKRSASEAIKGETLKGKSLRQMTARPVAKKKQTSAFIEGLRSISVKEAMKDADFSGWMSKKGSGAMSTWKTRFFTLHGTRLSYFSSTTDTRERGLIDITAHRVVPAKEDDKLVSLYAASTGKGRYCFKLLPPQPGSKKGLTFTQPRTHYFAVDNKEEMRGWMAALIKTTIDIDTSVPIISSYTTPTVSLSKAQEMLAEAREETKLREQQMLENEEDEDQFLWDQQQLQQQQHDNNQGQADRTISASTQRTSDEDNTISTPNLSSANNTTIGSNGFSSPFLLASGLLSPGVARNSSMRGTEKKGKFSTEEDYFGDNSKHKTDKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *: ..**: :::.. .: *:. .* . * .. :.. *:* . * :..* * : . :.*::* .: *. .* .* :*:* :: : :***: :: : :: * :::. : *:: . : :: . .: . *. : :. :*:: :.:**.:. * :*.:. * .: ...** *..* * :** :...:: *::* *. *:*.:.: :*:*::. * *.**: * .: .: * *:: :.:*:.* :*.:. * :.::.: : * *.:.: :* :*.: .* *:**:.:* *.... . *. * : : .*: ** :**: .:*:: :. *::* :: :: :.** . :*:.* *. .* . :: *. .* *: : :::: :::**: . .*.:: : . *.*: . :*:* ", "identical_positions": 91, "similar_positions": 206, "identity": "8.75%" }, { "cls_id": "homologset.agr.SGD:S000000918", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40072-1", "uniprot_id": "SLX8_YEAST", "id": "P40072-1", "name": "E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8", "aln": "MARRPDNQNPEGENLRIKRVRLESVRQNDEEEENEVSRTQNIVTDNRHDSPEAVVEIIGERALENTSEEDGDDDLSLFRALEEDPGSDHNTSNNDSGNHDRETMHTEEPEASSGNNITLTNNVEELHTMDVLSQTANTPSASPMLDAAPPTTKPGTNSKEQTVDLTADAIDLDAEEQQVLQISDDDFQEETKEAPKEYGAAKDYRCPIC----FEPPETALMTLCGHVFCCPCLFQMVNSSRTCRQFGHCALCRSKVYLKDVRLIILRKKQVKKKVKS-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "X2J791-1", "uniprot_id": "X2J791_DROME", "id": "X2J791-1", "name": "RING-type domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MFPSWHSLLRWKPLKMEGLRRAGDGMKTLETVDLTTDDEERPVLRLLSD-------------RNNGHYLCPIC----MSLPDHPVATTCGHIFCKECLTTALN------QLHYCPLCKN--FVTSFFRIYT------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IR26-1", "uniprot_id": "Q8IR26_DROME", "id": "Q8IR26-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-MEEPKSVSTAELPSTSTGASSSSSTLSNNVSYDKIAWTRDITEPLAEESSTSQLRPLGTSIPTNSTASELKKSNTSYSFTGDYLSGGNKADLKGGYPFGGTDTDTKANEKDKEKEHTADDSLYECNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCKAAVDKD-KVIPLYGRNSTHQEDPRNKVPPRPAGQRTEPDPVPGFPGFGFGDGFHMSFGIGAFPFGFITSRLNFFEPRPPADIRRLHEDEPWALSKLFWHFVVFVIYGLLVPIVHGSSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: .. : : * : : . *: : : : * : :* * .. : . ", "identical_positions": 5, "similar_positions": 20, "identity": "1.75%" }, { "cls_id": "homologset.agr.SGD:S000000919", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PC14-1", "uniprot_id": "RL23_DANRE", "id": "Q6PC14-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62830-1", "uniprot_id": "RL23_MOUSE", "id": "P62830-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62829-1", "uniprot_id": "RL23_HUMAN", "id": "P62829-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62832-1", "uniprot_id": "RL23_RAT", "id": "P62832-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y4M0-1", "uniprot_id": "A0A8I5Y4M0_RAT", "id": "A0A8I5Y4M0-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48159-1", "uniprot_id": "RL23_DROME", "id": "P48159-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGTAGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAGVGDMFVATVKKGKPELRKKVMPAVVIRQRKPFRRRDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNASSIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX42-1", "uniprot_id": "RL23B_YEAST", "id": "P0CX42-1", "name": "Large ribosomal subunit protein uL14B", "aln": "MSGN---GAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . *: * ******** ***::* **.:*::*:*:*:*: .**:***:*.:*.*.:***:*.:*:***** **:*:** *. *:*** :***::* **.* **:*********:.** ** ***:***:. .", "identical_positions": 79, "similar_positions": 39, "identity": "56.43%" }, { "cls_id": "homologset.agr.SGD:S000000920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E7F6M0-1", "uniprot_id": "E7F6M0_DANRE", "id": "E7F6M0-1", "name": "Cytoplasmic protein", "aln": "--MTEEVIVIAKFDYMAQQDQELDIKKNERLWLLDDSKSWWRVRNATNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKTGMRETASN-ADSDFYPDNG----------ERLYDLNLPALVKFSYAAEREDELSLVKGTRVIVMEKCSDGWWRGSYNGRSGWFPSNYVTEDADGSASN----DSAG--LSDKLSAVVQSANG------NRVLHTVQALYPFSSGNDEELNFEKGEVMDVVEKPENDPEWWKCRKSDGQMGLVPKNYVTVLQESHNSASMPGPP-TPDCDYIEPSSSGRFAG--KQWYYGKVTRHQAEVALNQRGSEGDFLIRDSESSPNDFSISLKAQSKNKHFKVQLKDNLYCIGQRKFNTMEELVEHYKKAPIFTSEQGDKLYLVKALAAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q4I8-1", "uniprot_id": "A0A8M9Q4I8_DANRE", "id": "A0A8M9Q4I8-1", "name": "Cytoplasmic protein", "aln": "--MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNASNRTGYVPSNYVERKNSLKKTSLVKNLKDTLGLGKTKRKTSARDPSPTPSTEAEYPSNGSAGGGGGGGAERIYDLNIPALVKFSYAAERDDELNLVKGERVVVMEKCSDGWWRGSHAGRVGWFPSNYVQEEVGYTDNDGVFGDTVGGFRSLKVGQGSAMANGRPGGSGSSVLHVVQTLYPFSSVTEEELNFEKGETMEVLEKPENDPEWWRCKNSRGIVGLVPKNYVVVLDDGPVAKGLGSSHGSPHISHTVPSRVGKFAG--KGWYYGNVTRHHAECALNERGVEGDFLIRDSESSPSDFSISLKAVGKNKHFKVQHQDGVYCIGQRRFSSMDELVEHYKKAPIFTSEQGDKLYLVKALG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TBD0-1", "uniprot_id": "A0A8N7TBD0_DANRE", "id": "A0A8N7TBD0-1", "name": "", "aln": "------------------------------------------------------------------MEMANLFKHFFRIGKVKQKGCVRDLPSS---AEKYEGDE-----------RLYDLNLPALVKFNYTAEREDELSLVKGTRVIVMEKCSDGWWRGSYNGLSGWFPSNYVTEDVDGTMRV----DSVN---PDKLASVGHNNNS------SQVLQTVQALYHFSSGNVEELNFNKYELMDVLEKPENDPEWWKCRKENGQVGLVPKNYVTVVQKTHKELGISGPH--PSNYDIKPSMDGKFGG--KQWYYGKLTRHQAEMVLNQRGVDGDFLIRDSESMPNDFSISLKALYKNKHFKVLLNDGFFCIGQRKFSTMEDLVEHYKKAPIFTSEHGDKLYLIKPLT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40073-1", "uniprot_id": "SHO1_YEAST", "id": "P40073-1", "name": "High osmolarity signaling protein SHO1", "aln": "MSISSKIRPTPRKPSRMATDHSFKMKKFYADPFAISSISLAIVSWVIAIGGSISS--ASTNESFPRFTWWGIVYQFLIICSLMLFYCFDLVDHY----RIFITTS---------IAVAFVYNTNSATNLVYADGPKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLEN----SLHRARRRGNRNTTPYQNN----VYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFEN-----TQPNTSEAVNLHLNTLQQRINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQ---NEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : : * : .:: *: .. . : ::: :: *. . . : ..: : : : *. . .:: *.. :: .. : .: ** : :.* :. ::. . : *.. . *. :: :: ... * . . . :.**:: *: ::* :. : .:* . : .:* : ..* ", "identical_positions": 18, "similar_positions": 88, "identity": "4.4%" }, { "cls_id": "homologset.agr.SGD:S000000921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWH0-1", "uniprot_id": "S38A7_MOUSE", "id": "Q8BWH0-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAQVS--INSDYSEWASSTDAGERARLLQSPCVDVVPK-SEGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMSKEP----DGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVVGTWYVTAIIIIKY-IWPDKEMRPGD--ILTRP--ASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYKGMP---VEEDVGR-----------------------------------ERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGG-LAACFIFIFPGLCLIQAKLSEMEEVKPAS---------WWALVSYGVLLVTLGAFIFGQTTANAIFVDLLA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6JWR2-1", "uniprot_id": "S38A7_RAT", "id": "Q6JWR2-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAQVS--INSDYSEWGSSTDAGERARLLQSPCVDVVPK-REGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEIAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEP----DGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASSLSVVGTWYVTAIVIIKY-IWPDKEMRPGD--ILTRP--ASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPQVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYKGTP---VEEDVGR-----------------------------------ERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGG-LAACFIFIFPGLCLIQAKLSEMEEVKPAS---------WWALVSYGVLLVTLGAFIFGQTTANAVFVDLLA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVC3-1", "uniprot_id": "S38A7_HUMAN", "id": "Q9NVC3-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAQVS--INNDYSEWDLSTDAGERARLLQSPCVDTAPK-SEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEP----EGASG-PWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKY-IWPDKEMTPGN--ILTRP--ASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVP---VEEDVGR-----------------------------------ERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGG-LAACFIFVFPGLCLIQAKLSEMEEVKPAS---------WWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEL1-1", "uniprot_id": "S38A7_DANRE", "id": "Q6DEL1-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MSRPDRAINSEAGDWGYSEDAGERAWLLQSPSVDSVQ-----PPSQSDDSRGGTSSLGAVFIVVNAALGAGLLNFPAAFNMAGGITAGVTLQMCMMAFIITGLVILAYCSQVSNESTYQEVVRAVCGKALGVICELAIAVYTFGTCIAFLIIIGDQLDKLIGAINNES----EKEISLHWYTDRKFTITLTSVLIILPLSIPKEIGFQKYASTLSVIGTWYVTIIVIVKY-IWPSKDVSPGI--IPVRP--ASWTDVFNAMPTICFGFQCHVSSVPVFNSMKKPEIRPWWGVVTISMIICLFVYTGTGVCGFLSFGSSVSQDVLMSYPSDDVAVAIARAFIIICVVTSYPILHFCGRAVLEGLWLRFKGEE---VETDVAK-----------------------------------ERRRRILQTLVWFCLTLILALFIPDIGRVISLIGG-LAACFIFVFPGLCLIQAKLSEHD-VRSNS---------WNAMVAYGVIMVTIGAFIFGQTTTNAIYKDIINNPNSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G4J0-1", "uniprot_id": "A0AC58G4J0_DANRE", "id": "A0AC58G4J0-1", "name": "", "aln": "MSVSSLRSVSFGPYTEQMILVFPASMYAEPFAWLTSPQRANTGRTSPFPRTPCLLLGALGALSGDRKSNGDCDSSGPRIRFVSTGIFNKPTCLREHSLLCSGETTQSSSRNQMLRDAAIKCCLRAAALCRIGITWQIDGLHILPEESYLTVAFQLKTGLEALRMEELARESIRSISLLSKPARGSDVPRLGSFGAIFIMLKSALGAGLLNFPWAFEKAGGVNTAISVEMVSLVFLISGLVILGYASSISRQNTYHDVVRNVCGRRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLCLSLYETVTGNTEAEMPHHWYTDYRFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLAATYLSVAVIAKYYLKDTHTADLT---PEHSQGLGSWASMFSVVPTICFGFQCHEASIAIYSSMENKKITHWVFISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYPGNDVVMIIARLLFGISIVTIYPIILLLGRSVILTQILRFWERR---TIMTPVF-----------------------------------EGRCRLILTILWITVTLLIAIFVPDMSEVISVIGG-ISAFFIFIFPGLCLIFVMQTEPINHRIRI-----------LLTGWGVVTIVIGAFIFGQSTTIAVMELAHKF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5WVQ9-1", "uniprot_id": "A5WVQ9_DANRE", "id": "A5WVQ9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELAKESI---SFLSKSSLETNEPRLGSLGAVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGRNTYQGVVTDICGPAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEINLS---PLYSSGISSWDSVFSVIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYSGGDVTMIVARLLFGISIITIYPIIVLLGRSVIQDPLLRRRLKH---TAVTESY-----------------------------------ESRTRVALTTAWVTVTLLIAVFIPDISKVISVVGG-VSAFFIFIFPGLCLIFVVQSESVSPTMRY-----------LLVTWGMITLLCGTLIFGQSTSVAIMQLITEV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A0Y7-1", "uniprot_id": "D4A0Y7_RAT", "id": "D4A0Y7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTRGSR---GLPEKPLPATTHPPLSSLGAVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLIRQPG--PLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATQGSPVLADPS-----------------------------------GPWVRLPLTFLWVAVTLAMALFLPDLSEIIGVIGG-LSAFFIFIFPGLCLISAVDTEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH7-1", "uniprot_id": "S38A8_MOUSE", "id": "Q5HZH7-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQPRGSR---GPLEKPLPAATHPTLSSLGAVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLIRQPG--PLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATRGPPVLADPS-----------------------------------GPWVRLPLTFLWVVVTLTMALFLPDLSEIISIIGG-VSSFFIFIFPGLCLICAVDTEPMGPRVKC-----------CLEAWGILSVLVGTFIFGQSTAVAMVELL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNN8-1", "uniprot_id": "S38A8_HUMAN", "id": "A6NNN8-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTPGSR---GLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGT-----PPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESH--PSLSP--ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPS-----------------------------------GLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGG-ISSFFIFIFPGLCLICAMGVEPIGPRVKC-----------CLEVWGVVSVLVGTFIFGQSTAAAVWEMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40074-1", "uniprot_id": "AVT6_YEAST", "id": "P40074-1", "name": "Vacuolar amino acid transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQGRASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRN-----------AWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPPQSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLYP-QAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAEENVSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHKTAVPLT---------TKIFKYTGLLLFIWGLIIMITCLTAALKLN--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:: ::::. ***:* :* ** * : . : : : : :: . . : .: : . * : : . : :::: :: * :: * . : : .:.: *** :.: .*:* :. .. *: : :* . ::...* : *.: ** ..: . . . : :: . :* * *:*:** : ::: *. :.* : : :: :*: .*: : : : * . : :*: :..:..::.::*. :: : *::*** * : * * .: . ", "identical_positions": 42, "similar_positions": 123, "identity": "6.33%" }, { "cls_id": "homologset.agr.SGD:S000000922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV55-1", "uniprot_id": "VAPA_MOUSE", "id": "Q9WV55-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRK-VCFKVKTTAPRRYCVRPNSGIIDPGSIVTVSVMLQPFDYD--PNEKSKHKFMVQTIFAP--PNISDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPLP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z270-1", "uniprot_id": "VAPA_RAT", "id": "Q9Z270-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRK-VCFKVKTTAPRRYCVRPNSGVIDPGSIVTVSVMLQPFDYD--PNEKSKHKFMVQTIFAP--PNISDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPLP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0L0-1", "uniprot_id": "VAPA_HUMAN", "id": "Q9P0L0-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRK-VCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYD--PNEKSKHKFMVQTIFAP--PNTSDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPMP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A092-1", "uniprot_id": "D4A092_RAT", "id": "D4A092-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASVSRAPAKPPQILVLDPPTDLKFKGPFTAVATAHLKLRNPSTRK-VCFKVKSTSPRRYCVRPNSGVIEPGCTVTVAAMLQPSCCG--PSQEVKHKFMVQTVFAP--PDTSDLEAVWRGVNPG---ELMDSKLRCVFEAPTESDKL----------------------------------------------------------------------------EDGLRLR------KVAHPDKPGPSSCTSLKKGYTTPLPVVLLVIGAVFFGFFLGKLVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY76-1", "uniprot_id": "VAPB_MOUSE", "id": "Q9QY76-1", "name": "Vesicle-associated membrane protein-associated protein B", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTVPRRYCVRPNSGVIDAGASLNVSVMLQPFDYD--PNEKSKHKFMVQSMFAP--PDTSDMEAVWKEAKPE---DLMDSKLRCVFELPAENAKPHDVEINKII-------------PTSASKTEAPAAAKSLTSPLDDTEVKKVMEECR---RLQGEVQRLREESRQLKEEDGLRVR------KAMPSNSPVAALAATGKEEGLSAR-LLALVVLFFIVGVIIGKIAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z269-1", "uniprot_id": "VAPB_RAT", "id": "Q9Z269-1", "name": "Vesicle-associated membrane protein-associated protein B", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTAPRRYCVRPNSGVIDAGASLNVSVMLQPFDYD--PNEKSKHKFMVQSMFAP--PDTSDMEAVWKEAKPE---DLMDSKLRCVFELPAENAKPHDVEINKIM-------------PTSASKTEAPVAAKPLTSPLDDAEVKKVMEECR---RLQGEVQRLREESRQLKEEDGLRAR------KALPSNSPMAALAASGKEEGLSAR-LLALVVLFFIVGVIIGKIAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95292-1", "uniprot_id": "VAPB_HUMAN", "id": "O95292-1", "name": "Vesicle-associated membrane protein-associated protein B/C", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTAPRRYCVRPNSGIIDAGASINVSVMLQPFDYD--PNEKSKHKFMVQSMFAP--TDTSDMEAVWKEAKPE---DLMDSKLRCVFELPAENDKPHDVEINKII-------------STTASKTETPIVSKSLSSSLDDTEVKKVMEECK---RLQGEVQRLREENKQFKEEDGLRMR------KTVQSNSPISALAPTGKEEGLSTR-LLALVVLFFIVGVIIGKIAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4N8-1", "uniprot_id": "Q9W4N8_DROME", "id": "Q9W4N8-1", "name": "", "aln": "-----MSKSLFDLPLTIEPEHELRFVGPFTRPVVTIMTLRNNSALP-LVFKIKTTAPKRYCVRPNIGKIIPFRSTQVEICLQPFVYD--QQEKNKHKFMVQSVLAPMDADLSDLNKLWKDLEPE---QLMDAKLKCVFEMPTAEANAENTSGGGAVGGGTGAAGGGSAGANTSSASAEALESKPKLSSEDKFKPSNLLETSESLDLLSGEIKALRECNIELR-RENLHLKDQITRFRSSPAVKQVNEPYAPVLAEKQIPVFYIAVAIAAAIVSLLLGKFFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSD3-1", "uniprot_id": "Q9VSD3_DROME", "id": "Q9VSD3-1", "name": "", "aln": "------MSDNTESKLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQE--QIKK-RHKFLLLAAEVT--GDISDVQEFWKMQNPN---ETRETKIKCELVPSKEDDFRQAGGSAVIS------------------------------TDNKDGEVHFDAQEVS-------EPMAKLLKQVSMLEDEHMALT------------DQIDGLRDQAIGRTFFYMAAIVIIILSAVAGAYYGKTRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40075-1", "uniprot_id": "SCS2_YEAST", "id": "P40075-1", "name": "Vesicle-associated membrane protein-associated protein SCS2", "aln": "-----------MSAVEISP-DVLVYKSPLTEQSTEYASISNNSDQT-IAFKVKTTAPKFYCVRPNAAVVAPGETIQVQVIFLGLTEEPAADFKCRDKFLVITLPSPYDLNGKAVADVWSDLEAEFKQQAISKKIKVKYLISPDVHPAQNQNIQENK--------------ETVEPVVQDSEPKEVPAVVNEKEVPAEPETQPPVQVKKEEVPPVVQKTVPHENEKQTSNS------TPAPQNQIKEAATVPAENESSSMGIFILVALLILVLGWFYR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.* : : .*:. : * : : **:*:* *: : **** . : . * : : :.**:: : . : . : .* :. : . *:: . . . : : : . . ", "identical_positions": 17, "similar_positions": 44, "identity": "6.05%" }, { "cls_id": "homologset.agr.SGD:S000000924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99K28-1", "uniprot_id": "ARFG2_MOUSE", "id": "Q99K28-1", "name": "ADP-ribosylation factor GTPase-activating protein 2", "aln": "-----MAASPSKTEIQTIFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSWLQLRCMQVGGNANATAFFRQHG------CMANDANTKYTSRAAQMYREKIRQLGSAALTRHGTDLWIDSMN-SAPSHSPEKKDSDFFTEHTQ-APAWDTAA---TDPSGTQ-------QPALPSESSSLAQPEQGPNTDLLGTSPQASLE---------------LKSSIIGKKKPAAAKKGLGAKKG--LGAQKVSNQSFTEIERQAQVAEKLREQQAADAKKQ-----AEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLV-SRSSISHSVLSEMQMIEQETPLSAKSS-RSQLDLFDDVGTFASGPP-------KYKDNPFSLGETFGSRWDSD------------AAWGMDRVEEKEPEV-TISSIRPISERTASRREVETRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGNMDGAHGGGT----VSLGN-VLPT-ADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MID3-1", "uniprot_id": "ARFG2_RAT", "id": "Q3MID3-1", "name": "ADP-ribosylation factor GTPase-activating protein 2", "aln": "-----MAAGPSKSEIQTLFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSWLQLRCMQVGGNANATAFFRQHG------CLANDANTKYNSRAAQMYREKIRQLGSTALARHGTDLWIDNMN-SAPSHSPEKKDSDFFTEHTQ-APAWDTAA---TDPSGTQ-------QPALPSESSSLAQPEPGPNTDLLGTSPQASLE---------------LKSSIIGKKKPAAAKKGLGAKKG--LGAQKVSNQSFTEIERQAQVAEKLREQQAADAKKQ-----AEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLV-SRSSISHSVLSEMQMIEQETPLSAKSS-RSQLDLFDDVGTFASGPP-------KYKDNPFSLGETFGSRWDSD------------AAWGMDRVEEKEPEV-TISSIRPISERTTSRREVESRISGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGDVDGAHGGGT----VSLGN-VLPT-ADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N6H7-1", "uniprot_id": "ARFG2_HUMAN", "id": "Q8N6H7-1", "name": "ADP-ribosylation factor GTPase-activating protein 2", "aln": "-----MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHG------CTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQ-PPAWDAPA---TEPSGTQ-------QPAPSTESSGLAQPEHGPNTDLLGTSPKASLE---------------LKSSIIGKKKPAAAKKGLGAKKG--LGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQ-----AEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLV-SRSSVSHSVLSEMQVIEQETPVSAKSS-RSQLDLFDDVGTFASGPP-------KYKDNPFSLGESFGSRWDTD------------AAWGMDRVEEKEPEV-TISSIRPISERATNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGS----VSLGN-VLPT-ADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5S0-1", "uniprot_id": "A0A8M2B5S0_DANRE", "id": "A0A8M2B5S0-1", "name": "ADP-ribosylation factor GTPase-activating protein 2", "aln": "-----MASEPNKTEIHTIFKRLRSIPTNKACFDCAAKNPSWASISYGVFLCIDCSGIHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANAMGFFRQHG------CTTNDTNAKYNSRAAQMYREKIRQLANAALSKYGTDLWIDSSSCAQPSP-VEKRETDFFDEHTQPAISWDMASPSLTDQNGAENVNPQLAQSNPKNSETPNTQPEEGPSIEGLSTSPKATIEDSMRLTSEEPQSPKDVKPSIIGKKKPVAAKKGLGAKKG--LGAQKVSSKSFSEVEKQAQVAEKMREEQAAEAKKQ-----ADESIVASMRLAYKELEIDRKMEEKKMQNLEGKKKEQAERLGMGFG-NRSAVSHSVMAEMQVIEQETPVGVKSSSRSKLDMFEEPG-FASGPP-------KYKDNPFTSGDSFGSRWDNDGG-------SSFSSWALEKEEPKDSEV-TISSIQPIGERLPSRRKPEVSVPVSESSEARQKFANAKAISSDMFFGRESNPEYEAKTRLEGMSGSTSISSADLFGDGS-VRPSGS----TGFDS-VLPSGPDIAQFKQGVKTVAGKMAVLANGVMNTIQDRYGSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D8S3-1", "uniprot_id": "ARFG3_MOUSE", "id": "Q9D8S3-1", "name": "ADP-ribosylation factor GTPase-activating protein 3", "aln": "------MGDPSKQDILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNSNASSFFHQHG------CATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLWLDSCA--APPVSPPPKEEDFFASHASLEVSGAMQASAQPESASSTP------WGLETTPEKHEGGPGQGPSVEGLNTPGKAAP-----------------EVSSIIKKKPNQAKKGLGAKKGS-LGAQKLTNTSFTEIEKQAQAVDKRKEQEDLARGAP-----KEESIVSSLRLAYKDLEISRKKDER--LNLSGQKKVEAERLGMGFGSCRSGISHSVTSDMQTIEQESPTLAKPRRKYQEDPEDSYFSSSSKWSEQSS---RYFDDPMELRSSSFSSWDDG------------ADSYWKKDSSRDPEP-AMRSTG-SSDRPSARRKPE-YEPIGSTDEAQKKFGNVKAISSDMYFGIQAQTDFETRARLERLSTSSSISSADLFDEQR-KQTAGN----YNLSN-VLPNAPDMAQFKQGVRSVAGKLSVFANGVMTSIQDRYGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN7-1", "uniprot_id": "ARFG3_RAT", "id": "Q4KLN7-1", "name": "ADP-ribosylation factor GTPase-activating protein 3", "aln": "------MGDPSKQDILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASSFFHQHG------CATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLWLDSCA--APPASPPPKEEDFFASHASLEVSGATQASAQPEPASSTP------WGLETTPEKHEGGPGQGPSVEGLNTPGKTAPA----------------EVSSIIKKKPNQAKKGLGAKKGS-LGAQKLTNTSFTEIEKQAQAVDKRKEQEDLARGTP-----KEESIVSSLRLAYKDLEIHKKQDER--LNLSGQKKAEAERLGMGFGSCRGGISHSVTSDMQTIEQESPTLAKPRRKYQEDPEDSYFSSSSKWSEQSSS--RYFDDPMELRSSHFSSWDDS------------ADSYWKKDSSRDPEP-ATKSTG-SSDRPSSRRKPE-YEPVGNTDEAQKKFGNVKAISSDMYFGIQSQTDFETRARLERLSTSSSISSADLFDEQR-KQTTGN----YNLSN-VLPNAPDMAQFKQGVRSVAGKLSVFANGVMTSIQDRYGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP61-1", "uniprot_id": "ARFG3_HUMAN", "id": "Q9NP61-1", "name": "ADP-ribosylation factor GTPase-activating protein 3", "aln": "------MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHG------CSTNDTNAKYNSRAAQLYREKIKSLASQATRKHGTDLWLDSCV--VPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTS------RPVETTLENNEGGQEQGPSVEGLNVP-TKATL----------------EVSSIIKKKPNQAKKGLGAKKGS-LGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVS-----KEESIVSSLRLAYKDLEIQMKKDEK--MNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSS----------SYFDEPVELRSSSFSSWDDS------------SDSYWKKETSKDTET-VLKTTG-YSDRPTARRKPD-YEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPR-KQPAGN----YSLSS-VLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JNX0-1", "uniprot_id": "A8JNX0_DROME", "id": "A8JNX0-1", "name": "", "aln": "--MASPAAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDTNWTWLQLRQMQLGGNANAAQFFRAHN------CSTTDAQVKYNSRAAQLYRDKLCAQAQQAMKTHGTKLHLEQTD--KSEGNEAAREEDFFAQCDN-EVDFNVQNNNVSKQDPNP--------PTVAPVISVETQQGGAPSVNLLNSVVPAAVP------------------SSIGARKVQPKKGGLGARKVGGLGATKVKTN-FADIEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERLGMGFNLRGSDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGGGGSSEKRESSVGGTSKLDKFELDALGYETIEPIGGSHSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFGNSKGFGSDQYFASE-QSSADVSASLNRFQGSRAISSSDYFGDGSPGGTGGNRASSVNFSAPDLDVESVKESVRQGVHKVAGRLSNLANDVMTSWQDKYGY-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38682-1", "uniprot_id": "GLO3_YEAST", "id": "P38682-1", "name": "ADP-ribosylation factor GTPase-activating protein GLO3", "aln": "MSNDEGETFATEQTTQQVFQKLGSNMENRVCFDCGNKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLDK-WTINNLRRFKLGGNHKARDFFLKNNGKQLLNTANVDAKTKYTSPVAKKYKIHLDKKVQKDMELYPSELVLNGQD---SSDSPLDTDSDASRSTSK-ENSVDDFFSNWQKPSSNS--------SSKLNVNTGSLAPKNNTTGSTPKTTVTKTRS------------------SILTASRKKPVLNSQDKKKHSILSSSRKPTRLTAKKVDKSQAEDLFDQFKKEAQQEK------------EDEFTNSSSSTKIRQNDYDSQFMNNSKGNNNN--------SIDDINTQPDEFNDFLNDTSNSFDTTRKEQQDTLTPKFAKLGFGMT-------MNDANDLAKQQKESQKIAQG-----------------PRYTGRIAER--YGTQKAISSDQLFGRGSFDEAANREAHDKLKTFDNATSISSSSYFGEDKEVDEFGNPINSSGSGAGNFD----------GRNSNN-----GFIDFNASADDELQMLRDVVEQGAEKLGSYLRDYLRK--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: :*.:* : *: ****. * *:*:*:.:*:::**:**. **.:***::*::*: **. *. :** :::*** .* ** :. *::.**.* .*: *: :: : :.* :: . : * . . . . .. . : * : : . . :* *.: : . . :::. : . .:: .. . :: :. * : : . : . : ::: : . . . . : . . . : : : . : . .. :.* . ..:.*. :*. : : . . . . : :. .. .: .:: *. * ::. .. : . ", "identical_positions": 51, "similar_positions": 145, "identity": "8.6%" }, { "cls_id": "homologset.agr.SGD:S000000925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCP0-1", "uniprot_id": "KC1G1_HUMAN", "id": "Q9HCP0-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPSREK---------------DERQRTTKPMAQRSA---HCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGR----------------QGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIE--ALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVG-----------RPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN-------------------------------------QVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTH8-1", "uniprot_id": "KC1G1_MOUSE", "id": "Q8BTH8-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK---------------DDRQRTTKTMAQRNT---HCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGR----------------QGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIE--ALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVG-----------RPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRNQTTSSERRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62761-1", "uniprot_id": "KC1G1_RAT", "id": "Q62761-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK---------------DDRQRTTKTMAQRNT---HCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGR----------------QGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIE--ALCENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDWVG-----------RPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN--------------------------------------QPRSLTAEWFVLAPL-SHPPAPT----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PRD4-1", "uniprot_id": "KC1G1_DANRE", "id": "Q5PRD4-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPREKE---------------ADRPVRSSKVPQGRS---GHSRPSSSSASSGVLMVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKTLGSA-----DGLPQVFYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGR----------------QGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIE--VLCENFPEEMATYLRYVRRLDFFEKPDYDYLRNLFTELFDRKGYAFDYSYDWVG-----------RQIPTPVGTVHVDSGASAIT-RESHAHRDRPSQHQPLRN-------------------------------------QVVSSTNGELNADDPLAAHSNAPITAQAEVEVVDEA--------KCCCFFKRKRKKNTPRHK--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y6M4-1", "uniprot_id": "KC1G3_HUMAN", "id": "Q9Y6M4-1", "name": "Casein kinase I isoform gamma-3", "aln": "MENKKKDK---------------DKSDDRMARPSGRSG---HNTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGR----------------PGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIG-----------KQLPTPVGAVQQDP-ALSSN-REAHQHRDKMQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62763-1", "uniprot_id": "KC1G3_RAT", "id": "Q62763-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK---------------DKSDDRMARPSGRSG---HSTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGR----------------PGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIG-----------KQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4X2-1", "uniprot_id": "KC1G3_MOUSE", "id": "Q8C4X2-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK---------------DKSDDRMARPSGRSG---HSTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGR----------------PGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIG-----------KQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQ----------------------------------------VVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BVP5-1", "uniprot_id": "KC1G2_MOUSE", "id": "Q8BVP5-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGELEEGRRMSKTGTSRS---NHG-VRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGR----------------PGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWAG-----------KPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62762-1", "uniprot_id": "KC1G2_RAT", "id": "Q62762-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGELEEGRRMSKTGTNRS---NHG-VRNSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGR----------------PGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWAG-----------KPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78368-1", "uniprot_id": "KC1G2_HUMAN", "id": "P78368-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGETEEGRRMSKAGGGRS---SHG-IRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGR----------------PGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAG-----------KPLPTPIGTVHTDLPSQPQL-RDKTQPHSKNQ---------------------------------------------ALNSTNGELNADDPTAGHSNAPITAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIW9-1", "uniprot_id": "A0A8M2BIW9_DANRE", "id": "A0A8M2BIW9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDFDKRGGGGG---------KGEAEDGKRMSKTGGSRT---GHGGSRGSGNNTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGNA-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRDVKPENFLVGR----------------PGTKRQHTIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCESFP-EMATYLRYVRRLDFFERPDYEYLRKLFTDLFDRNGYVFDYEYDWVG-----------KPLPTPIGPMPSDTPLQPSN-RDKAQPQTKNQSPEPKGSESQPT-----------PVTNRELLGSHLTADRLGGSVQVMSSTNGEVNTDDPTAGHSNAPITAPAEVEVADDT--------KCCCFFKRRKRKALQRHK--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHL4-1", "uniprot_id": "A0A0B4KHL4_DROME", "id": "A0A0B4KHL4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQRRERQASGGGPQTTTAGPSAGNVANATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGR----------------TSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE--VLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTG-----------KTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVP--------------KPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDET--------KCCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSNSRDSVLNNPSQDYIQQATSQHTLRYPPSASMLTPTPTTNTPTLPL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39962-1", "uniprot_id": "KC13_YEAST", "id": "P39962-1", "name": "Casein kinase I homolog 3", "aln": "MSQRSSQH-----------------IVGIHYAVGPKIG-----------EGSFGVIFEGENILHSCQAQTG---SKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGC-----VGIPHAYYFGQEG-MHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNPRVNGNTARNNVNTNSKTRNTTPVATPKQQAQN----------SYNKDNSKSRISSNPQSFTKQQHVLKKIEPNSKYIPETHSNLQRPIKSQSQTYDSISHTQNSPFVPYSSSKANPKRSNNEHNLPNHYTNLANKNINYQSQRNYEQENDAYSDDENDTFCSKIYKYCCCCFCCC-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . **:: * *: . : * . : .. : ** ****:** :* ****: *:* *: *. *:*: :::* * :* ::::*** ******: * *.*::**. *:* *:: *:. :* : *****:**:***:.: ..: : *:::***:**:* * *::******:***:***********:*:*********:***:*:************** . * :*:*** **: : * : * :: ***:*.* *.* * ***::* *: : : .. : :** . . .. * . :: : . * :. ", "identical_positions": 140, "similar_positions": 94, "identity": "23.81%" }, { "cls_id": "homologset.agr.SGD:S000000927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96PU5-1", "uniprot_id": "NED4L_HUMAN", "id": "Q96PU5-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATGLG-EPVYGLSE------DEGESR-------------------------------------------------ILR----------VKVVSGID------------LAKKDIFGASDPY---------------------------------------------------------------------------------------------VKLSLYVADENRE----------------------LALVQTKTI---KKTLN---------PKWN-EEFY---------------------------FRVNPSNHR---------------------------LLFEVFDEN----------------------------------------------------RLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPP---------------------------------------LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGG-DVPEPWETIS-EEVNIAGDSLGLALPPPPAS---------------------------------------------------------------------------------------------------PGSRTSPQELSEELSRRLQITPD---------------SNGEQ------------------FSSLIQREPSSRLRSCSVTDAVAEQGHLPPPS--APAGRARSSTVTGGEEPT-PSVAYVHTTPGLP--SGWE-ERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ----------------------SPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSL----------NPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSREFKQKYDYFRKKLKKPADIPN--RFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT---ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFI0-1", "uniprot_id": "NED4L_MOUSE", "id": "Q8CFI0-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "-------------------------------------------------------------------------------------------------MSLCEAPVHVGDKELK---YFQIPQ--------------------------------------------------------------MLSQLS-LLASHHSRGLEFSGGQGESR-------------------------------------------------ILR----------VKVVSGID------------LAKKDIFGASDPY---------------------------------------------------------------------------------------------VKLSLYVADENRE----------------------LALVQTKTI---KKTLN---------PKWN-EEFY---------------------------FRVNPSNHR---------------------------LLFEVFDEN----------------------------------------------------RLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSEQRDDMEHGWEVVDSNDSASQHQEELPPPP---------------------------------------LPPGWEEKVDNLGRTYYVNHNNRSTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEASEGGGEGPEPWETIS-EEMNMAGDSLSLALPPPPAS---------------------------------------------------------------------------------------------------PVSRTSPQELSEEVSRRLQITPD---------------SNGEQ------------------FSSLIQREPSSRLRSCSVTDTVAEQAHLPPPS--TPTRRARSSTVTGGEEPT-PSVAYVHTTPGLP--SGWE-ERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLVEPQIRRPRSLSSPTVTLSAPLEGAKDSPIRRAVKDTLSNPQ----------------------SPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKASL----------NPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSREFKQKYDYFRKKLKKPADIPN--RFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT---ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JUY1-1", "uniprot_id": "A0A0G2JUY1_RAT", "id": "A0A0G2JUY1-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "-----------------------------------------------------------------------------------MAHRLRFHFGSGRSNTAPESEILDQEREED---FFMAFQ--------------------------------------------------------------TLPRRSSPHPFTQNAGEDSGLQEGVGA-------------------------------------------------LKRSSSMFI----PQLLAGVDARPTRSSSMKISLQRKAADGATDSCGPQEGPDDRPPSAQGDLGDQAAATRVSAQIGSSEPSPVDTPGSSPPRAAWDPGTLVNGTCDHRGPSPRLAEDTEEATPGLRIQHRASSADVRQVRLLPFGPDGQAEPRRWSLQHVPDASGSSGKRCFVFQLQQPHQG---TVGLG---------SDFN-FGFTGTKGDRLVRYPRIRLERSTSYPTQPRAGRVSPTEDRGTPEASPRRMVPEIRRTNSERTPQSPGCMFKIRQDQNAGQQHFRILVTRGPEEAPQNQEETPKSPGHPGTG-----------------VPTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPR---SHKSRVKGFLRLKMAYMPKNGGQDEENSEQRDDMEHGWEVVDSNDSASQHQEELPPPP---------------------------------------LPPGWEEKVDNLGRTYYVNHNNRSTQWHRPSLMDVSSES--DNNIRQINQEAAHRRFRSRRHISEDLEPEASEGGGEGPEPWETIS-EEVNMAGDSLSLALPPPPAS---------------------------------------------------------------------------------------------------PVSRTSPQELSEELSRRLQITPD---------------SNGEQ------------------FSALIQREPSSRLRSCSVTDTVAEQAHLPPP-----------------------SVAYVHTTPGLP--SGWE-ERKDAKGRTYYVNHNNRTTTWTRPIMQLA-EDGASG----------------SATNSNNHLVEPQIRRPRSLSSPTVTLSAPLEGAKDSPIRRAVKDTLSNPQ----------------------SPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKASL----------NPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSREFKQKYDYFRKKLKKPADIPN--RFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT---ELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PD40-1", "uniprot_id": "A0A8M9PD40_DANRE", "id": "A0A8M9PD40-1", "name": "E3 ubiquitin-protein ligase NEDD4-like", "aln": "-----------------------------------------------------------------------------------MSHRLRLYFGSGRSNTAPELEELNGTVEEEGDISYNSTG--------------------------------------------------------------AMVVHAQPRNGGHAESPEPGTVVGSDAS------------------------------------------------LKRSSSMFI----PQLQGQAESRTTKSTSVQISLQRTTAPHEDALPFDPPPAYPQDPAPPYTEPGESLPLPPPPTYYKSCQNVEQTQKDTEPKRQ----VFCVRPCDGQNGYTHGNPQGITIGGVCIRRRSADGSDVQQFRIMPYSEDGHNG-HNWSVQQCSDRGPGAQRLIFQLQKDQGRQP---SSTSQ---------PDVSDLGITGSKGSRLVRYPRIRLERSTSQP-----LQPRGAPSRLGSMPNLHAPISEMETESDFIENGAQGCTFKIRKEQNSQQPKFKIYFSQGGEHSPILERNISIGKAPTCSNPQAHIGLDRPKNGHFNNGQTRDDFLGQVDVPLTHLPTEDPAMERPYTFKDFLLRPR---SHKSRVKGYLRLKMAYLPKNGGHEEESGEMREEAEG-WEVTDSTDPGSQRPQQLLPP----------------------------------------LPPGWEEKVDNLGRTYYVNHNNRTTQWKRPSSVDVVSETENDNQLRQINQEA-HRVFRSRRHISEDLENEQLDIR-DIDDSWEPISEEDPTLLTDGLNHSLSGPSSL---------------------------------------------------------------------------------------------------AMPLSSTPDFSDEISLRLSLAPD---------------TNGEIP----------------GPSSAVQSHLSSRLRSSSMTDGVSDQAQPPTPTQSSQTRRTRAQTVTGVEDTMSPSASYALTTPGLP--PGWE-ERKDPKGRTYYVNHNNRSTTWTRPILQQHTEDGASTSVAAVGGATAATPPASTPSTSSGHLSEPQVRRPRSLSSPTVTLSSPLEGANNVPIRRAVKDTFSNPQ----------------------SPQPSPYSSPKTQHKANQSFLPPGWEMRIAPNGRPFFIDHNSRTTTWEDPRLKYPVHMRTKASL----------DPGDLGPLPPGWEERVHADGRTFYIDHNNKKTQWEDPRLQSPAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSREFKQKYDYFRKKLKKPADIPN--RFEMKLHRNNIFEESYRRIMSLKRPDSLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT---ELDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNDNKKEYIDLVIQWRFVNRVQKQMNAFLEGFTELIPIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGTPDKLPRAHTCFNRLDLPMYETFEDLREKLLMAVENAQGFEGVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46935-1", "uniprot_id": "NEDD4_MOUSE", "id": "P46935-1", "name": "E3 ubiquitin-protein ligase NEDD4", "aln": "-----------------------------------------------------------------------------------------------------MSSDMAADESEA-----------------------------------------------------------------------PVLSEDEVWEFCLDKTEDGGGSPGSD-----------------------------------------------------------------VTDTCEPPCGCWELNPNSLEEEHVLFTADPYLELHN-------------DDTRVVRVKVIAGIG-----------LAKKDILG-----------ASDPYVRVT------------------------------------------------LYDPMSGILTSVQTKTI---KKSLN---------PKWNEEILFRVL----------------------------PQRHR---------------------------ILFEVFDE----------NR------------------------------------------LTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPR---SHKSRVKGYLRLKMTYLPKN-GSEDENADQAEELEPGWVVLDQPDAATHLPHPPEPSP---------------------------------------LPPGWEERQDVLGRTYYVNHESRRTQWKRPSPDDDLTDE--DNDDMQL---QAQRAFTTRRQISEDVDGPD---NRESPENWEIVREDENTEYSG---QAVQSPP-----------------------------------------------------------------------------------------------------SGHIDVQTHLAEEFNTRLAVCGN---------------PATSQ--------------------PVTSSNHSSRGGS-LQTCIFEEQPTLPVLLP---------------------------TSSGLP--PGWE-EKQDDRGRSYYVDHNSKTTTWSKPTMQ-------------------------------------------------------------------------------------------------------------------------------------------------DDPRSKIPAHLRGKT------------DSNDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRLQNVAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSRDYKRKYEFFRRKLKKQTDIPN--KFEMKLRRANILEDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPT---ELDLRFIIDEELFGQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62940-1", "uniprot_id": "NEDD4_RAT", "id": "Q62940-1", "name": "E3 ubiquitin-protein ligase NEDD4", "aln": "---------------------------------------------------------------------------------------------------------MAADDTEA-----------------------------------------------------------------------PVLSEDEVWEFCLDKNEEGGGSPGSD-----------------------------------------------------------------VTDTCEPPCGCWELNPSSLEEEHVLFTAESIISSFNN------------DDTRVVRVKVIAGIG-----------LAKKDILG-----------ASDPYVRVT------------------------------------------------LYDPMSGVLTSVQTKTI---KKSLN---------PKWNEEILFRVL----------------------------PQQHR---------------------------ILFEVFDE----------NR------------------------------------------LTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPR---SHKSRVKGYLRLKMTYLPKN-GSDDENADQAEELEPGWVVLDQPDAATHLQHPPEPSP---------------------------------------LPPGWEERQDVLGRTYYVNHESRTTQWKRPSPEDDLTDD--ENGDIQL---QAHGAFTTRRQISEDVDGPD---NHESPENWEIVREDENTIYSG---QAVQSPP-----------------------------------------------------------------------------------------------------SGHPDVQVRLAEELDTRLTMYGN---------------PATSQ--------------------PVTSSNHSSRGGS-SQTCIFEEQPTLPVLLP---------------------------TSSGLP--PGWE-EKQDDRGRSYYVDHNSKTTTWSKPTMQ-------------------------------------------------------------------------------------------------------------------------------------------------DDPRSKIPAHLRGKTPV----------DSNDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRMQNVAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPYSRDYKRKYEFFRRKLKKQTDIPN--KFEMKLRRANILEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATEDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPT---ELDLRFIIDEELFGQTHQHELKTGGSEVVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46934-1", "uniprot_id": "NEDD4_HUMAN", "id": "P46934-1", "name": "E3 ubiquitin-protein ligase NEDD4", "aln": "-MAQSLRLHFAARRSNTYPLSETSGDDLDSHVHMCFKRPTRISTSNVVQMKLTPRQTALAPLIKENVQSQERSSVPSSENVNKKSSCLQISLQPTRYSGYLQSSNVLADSDDASFTCILKDGIYSSAVVDNELNAVNDGHLVSSPAICSGSLSNFSTSDNGSYSSNGSDFGSCASITSGGSYTNSVISDSSSYTFPPSDDTFLGGNLPSDSTSNRSVPNRNTTPCEIFSRSTSTDPFVQDDLEHGLEIMKLPVSRNTKIPLKRYSSLVIFPRSPSTTRPTSPTSLCTLLSKGSYQTSHQFIISPSEIAHNEDGTSAKGFLSTAVNGLRLSKTICTPGEVRDIRPLHRKGSLQKKIVLS-----------NNTPRQTVCEKSSEGYSCVSVHFTQRKAATLDCETTNGDCKPEMSEIKLNSDSEYIKLMHRTSACLPSSQNVDC---QININGELERPHSQMNKNHGILRRSISLGGAYPNISCLSSLKHNC-----SKGGPSQLL---------------------------IKFASGNEGKVDNLSRDSNRDCTNELSNS--------------------------------CKTRDDFLGQVDVPLYPLPTENPRLERPYTFKDFVLHPR---SHKSRVKGYLRLKMTYLPKTSGSEDDNAEQAEELEPGWVVLDQPDAACHLQQQQEPSP---------------------------------------LPPGWEERQDILGRTYYVNHESRRTQWKRPTPQDNLTDA--ENGNIQL---QAQRAFTTRRQISEETESVD---NRESSENWEIIREDEATMYSN---QAFPSPPP----------------------------------------------------------------------------------------------------SSNLDVPTHLAEELNARLTIFGN---------------SAVSQ--------------------PASSSNHSSRRGS-LQAYTFEEQPTLPVLLP---------------------------TSSGLP--PGWE-EKQDERGRSYYVDHNSRTTTWTKPTVQATVETSQLT--------------------SSQSSAGPQSQASTSDSGQQVTQPSEIE----------------------------------------------------------QGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPAHLRGKTSLD---------TSNDLGPLPPGWEERTHTDGRIFYINHNIKRTQWEDPRLENVAITGPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSRDYKRKYEFFRRKLKKQNDIPN--KFEMKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDN-YTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPT---ELDLRFIIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIENTQGFDGVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVI3-1", "uniprot_id": "NEDD4_DROME", "id": "Q9VVI3-1", "name": "E3 ubiquitin-protein ligase Nedd-4", "aln": "-----------------------------------------------------------------------------------MSARSSGLVAAAALPVPSSSSSVAGGDVPRP----------------------------------------------------------------------PPRRRAASVAGQQQTRQEFGNGYTPRRS-----------------------------------------------------------LAAVNDSGDSCHLRIVVLTGQSLAKKDIFGASDPYVRIDLN-------------------------------------------------------------------------------------------------------------------TINGDINIDSVLTKTK---KKTLN---------PTWNEEFIFRVK----------------------------PSEHK---------------------------LVFQVFDEN----------------------------------------------------RLTRDDFLGMVELTLVNLPTEQE--GRTIGEQSYTLRPRRSVGAKSRIKGTLRIYHAFIRETREQSEPSSGNSD---GEWEHVEATNAGETSAQPHPFPTG--------G--------------------------HDALPAGWEERQDANGRTYYVNHTARTTQWDRPTVLNSHSSQ---STDDQL-----ASDFQRRFHISVDDTESGRSADSISHNSIEDNN-NAAGLAYTPKTAATSSAPPN---------------------------------------------------------------------------------------------------TPTNNNGILAQIAMQYRAEEDQD---------------PTVDHT----------------SFVYNSLRHPVAHRQPEISATSLQNDLRPVREAP-------------GVPDIAITNPFTRRAAGNMAGGAGWQQERRRQQMQLHIQQHQQRQQQQQQNRILLDVDHRQQE-------------------PQHRGQRHQQQHRPSNEDTDHTDSHNPSDISAPSTRRNSEEDNAAVPP----------------------MEQN---------TGGEEEPLPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNGRASPMPNQTRR----------VEDDLGPLPEGWEERVHTDGRVFYIDHNTRTTQWEDPRLSNPNIAGQA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPYSRDYKQKYEYFKSHIRKPTNVPN--KFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLDYGGLAREWFYLLSKEMFNPYYGLFEYSAMDN-YTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWIKENDPR---ILELTFCLDEDVFGQKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQNIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIEKWGTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAIEGSQGFAGVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39940-1", "uniprot_id": "RSP5_YEAST", "id": "P39940-1", "name": "E3 ubiquitin-protein ligase RSP5", "aln": "------------------------------------------------------------------------------------------------MPSSISVKLVAAESLYKR----------------------------------------------------------------------DVFRSPDPFAVLTIDGYQTKSTSAAKKT---------------------------------------------------------------LNPYWNETFKFDDINENSILTIQVFDQKKFKKKDQG---------------------------------------------------------------------------------------------------------------------------FLGVVNVRV---GDVLG----------HLDEDTATSSG---------------------------RPREET---------------------------ITRDLKKSN------------------------------------------------------DGMAVSGRLIVVLSKLPSSSPHSQAPSGHTASSSTNT---SSTTRTNGHSTSSTRNHSTSHPSRGTAQAVESTLQSGTTAATNTATTSHRSTNSTSSATRQYSSFEDQ--------------------------YGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQTEAER-----GNQLN---ANTELERRQHRGRTLPGGS-------------------------------------------------------------------------------------------------------------------------------------------------SDNSSVTVQVGGG---------------SNIPP---------------------VNGAAAAAFAATGGTTSGLG----------------------------------------ELP--SGWE-QRFTPEGRAYFVDHNTRTTTWVDPRRQ-------------------------------------------------------------------------------------------------------------------------------------------------QYIRTYGPTNTTIQQQP-----------VSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPS-SLDQNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQYKRDFRRKVIYFRSQP-ALRILPG--QCHIKVRRKNIFEDAYQEIMRQTPED-LKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDN-YTIQINPNSGIN-PEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDG--VLDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYR-GYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9H0M0-1", "uniprot_id": "WWP1_HUMAN", "id": "Q9H0M0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATASPRSDTSNNHSGRL----------------------------------------------------------------QLQVTVSSAKLK-RKKNWFGTAIYTEVVVD--------------------------------------------------------------------------------------------------------------------------------GEITKTAKSSSSSN------------PKWDEQLTVNVT-----------------------PQTT---------------------------------LEFQVWSHR----------------------------------------------------TLKADALLGKATIDLKQALLIHNRKLERVKEQLKLSLENKNGIAQT--GELTVVLDGLVIEQENITNCSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGIDN---------------------------------HVPTSTLVQNSCCSYVVNGD-----NTPSSPSQVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTSTTVEDPPVQEILTSSENN----------------------------------------------------------------------------------------------ECIPSTSAELESEARSILEPDTSNSRS---------------SSAFEAAKSRQPDGCMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTT---------------------------WERPQPLPPGWE-RRVDDRRRVYYVDHNTRTTTWQRPTMESVRNFEQWQ------------------------SQRNQLQGAMQQFNQRYLYS----------------------------------------------------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG---------------------LQNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGG--PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAYERGFRWKLAHF-RYLCQSNALPS--HVKINVSRQTLFEDSFQQIMALKPYD-LRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNN-YCLQINP-ASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEEC-GLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYR-HYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FIK1-1", "uniprot_id": "F7FIK1_RAT", "id": "F7FIK1-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------------------------------MSSLTEEIASSSSSYPQCLEQFLVHKFQFWALQTCFSYYS----------------------------------------------------------------------ICHNQGEFWDMATASPRSDTSDNHSGRL----------------------------------------------------------------QLKVTVSSAKLK-RKKNWFGTAIYTEVIVD--------------------------------------------------------------------------------------------------------------------------------GEIKKTAKSSSSSN------------PKWDEQLIVNVA-----------------------PQTT---------------------------------LEFRVWSHH----------------------------------------------------TLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQT--GELTVVLDGLVIEPEAVTNRSSSPPIEIQQNGDAVHENGDPLTRTTPRLAVEGTIGIDN---------------------------------HVSTSTVVPSSCCSHIVNGE-----NTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSS-VLADSTSAMGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHS----------------------------------------------------------------------------------------------ECIPSASAEVGPEARSLIDPD-SDSRN---------------NSGFD--KVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTT---------------------------WERPQPLPPGWE-RRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQ------------------------SQRNQLQGAMQQFNQRYLYS----------------------------------------------------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG---------------------LPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGG--PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAYERSFRWKLAHF-RYLCQSNALPS--HVKINVSRQTLFEDSFQQIMALKPYD-LRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNN-YCLQINP-ASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEEC-GLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYR-HYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C863-1", "uniprot_id": "ITCH_MOUSE", "id": "Q8C863-1", "name": "E3 ubiquitin-protein ligase Itchy", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSGPQLDSMGSLTMKS----------------------------------------------------------------QLQITVISAKLKENKKNWFGPSPYVEVTVD--------------------------------------------------------------------------------------------------------------------------------GQSKKTEKCNNTNS------------PKWKQPLTVIVT-----------------------PTSK---------------------------------LCFRVWSHQ----------------------------------------------------TLKSDVLLGTAGLDIYETLKSNNMKLEEVVMTLQLVGD-KEPTETM--GDLSVCLDGLQVEAEVVTNGETSCSESTTQNDDGCRTRDDTRVSTNGSEDPEVAASGEN---------------------------------KRANGNNSPS-----LSNGG-----FKPSRPP----RPSRPPPPTPRR----PASVNGSPSTNSDSDGSSTG--SLPP---------TNTNVN-----------------------------------------------------------------------------------------------------------------TSTSEGATSGLIIPLTISGGSG---------------PRPLN-------------------TVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTT---------------------------WDRPEPLPPGWE-RRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ------------------------LQRSQLQGAMQQFNQRFIYGNQD-----------------------------------------------LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG---------------------QLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDNG---PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAYVRDFKAKVQYF-RFWCQQLAMPQ--HIKITVTRKTLFEDSFQQIMSFSPQD-LRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDN-YCLQINP-ASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC-GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYR-HYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9T1-1", "uniprot_id": "A0A0G2K9T1_RAT", "id": "A0A0G2K9T1-1", "name": "E3 ubiquitin-protein ligase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSAPQLDSMGSLTMKS----------------------------------------------------------------QLQITVISAKLKENKKNWFGPSPYVEVTVD--------------------------------------------------------------------------------------------------------------------------------GQSKKTEKCNNTNS------------PKWKQPLTVIVT-----------------------PMSK---------------------------------LCFRVWSHQ----------------------------------------------------TLKSDVLLGTAGLDIYETLKSNNMKLEEVVMTLQLVGD-KEPTETM--GDLSVCLDGLQVEAEVVTNGETSCSEGATQNDAGCRPKDETRVSTNGSEDPEVAASGEN---------------------------------KRANGNNSPS-----LSNGG-----FKPSRPP----RPSRPPPPTPRR----PASVNGSPSTNSDSDGSSTG--SLPP---------TNTNVN-----------------------------------------------------------------------------------------------------------------SSASEGAASGLIIPLTISGGSG---------------PRPLN-------------------TVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTT---------------------------WDRPEPLPPGWE-RRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ------------------------LQRSQLQGAMQQFNQRFIFGNQD-----------------------------------------------LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG---------------------QLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDNG---PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAYVRDFKAKVQYF-RFWCQQLAMPQ--HIKITVTRKTLFEDSFQQIMSFSPQD-LRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDN-YCLQINP-ASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC-GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYR-HYTRTSKQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBH0-1", "uniprot_id": "WWP2_MOUSE", "id": "Q9DBH0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASASSSRAGVALPFEKS----------------------------------------------------------------QLTLKVVSAKPKVHNRQPR-INSYVEVAVDG-----------------------------------------------------------------------------------------------------------------------------LPSETKKTGKRIGSSE------------LLWNEIIVLNVT-----------------------AQSH---------------------------------LDLKVWSCH----------------------------------------------------TLR-NELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGSVPNGSAVTDGSQPPSRESSGTAIAPETRHQPPSTNCFGGRSRT---------------------------------HRHSGGSART----ATAASE-----QSPGARN-----RHRQPVKNSSSSGLANGTVNEEPTPASEPEESSVVGVTSLP--------AAALSVS---------------------------------------------------------------------------------------------------------------SNPNTTSLPAQSTPAEGEEASTSG---------------TQQLP-----------------AAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTT---------------------------WER--PLPPGWE-KRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQ------------------------SQRNQLQGAMQHFSQRFLYQ----------------------------------------------------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG---------------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQG--SP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAYDRSFRWKYHQF-RFLCHSNALPS--HVKISVSRQTLFEDSFQQIMNMKPYD-LRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNN-YCLQINP-ASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEEC-GLELFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYR-HYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B4F767-1", "uniprot_id": "B4F767_RAT", "id": "B4F767-1", "name": "E3 ubiquitin-protein ligase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASASSSRAGVALPFEKS----------------------------------------------------------------QLTLRVVSAKPKVHNRQPR-INSYVEVAVDG-----------------------------------------------------------------------------------------------------------------------------LPSETKKTGKRIGSSE------------LLWNEVIVLNVT-----------------------AQSH---------------------------------LDLKVWSCH----------------------------------------------------TLR-NELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGSVPNGSAVTDGSQPPSRESSGTALAPETRHQPPSTNCFGGRSRT---------------------------------HRHSGGSART----ATATGE-----QSPGARN-----RHRQPVKNPSSSGLANGTVSEEPTTASDPEELSVVGVTSPP--------AAASSVS---------------------------------------------------------------------------------------------------------------PNPNTTSLPAPSTPAEGEEPSTSG---------------TQQLP-----------------AAAQAPDALPAGWEQRQLPNGRVYYVDHNTKTTT---------------------------WER--PLPPGWE-KRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQ------------------------SQRNQLQGAMQHFSQRFLYQ----------------------------------------------------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG---------------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQG--SP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAYERSFRWKYHQF-RFLCHSNALPS--HVKISVSRQTLFEDSFQQIMNMKPYD-LRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNN-YCLQINP-ASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLRDLESIDPEFYNSIIWIKENNLDEC-GLELFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYR-HYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00308-1", "uniprot_id": "WWP2_HUMAN", "id": "O00308-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASASSSRAGVALPFEKS----------------------------------------------------------------QLTLKVVSAKPKVHNRQPR-INSYVEVAVDG-----------------------------------------------------------------------------------------------------------------------------LPSETKKTGKRIGSSE------------LLWNEIIILNVT-----------------------AQSH---------------------------------LDLKVWSCH----------------------------------------------------TLR-NELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRT---------------------------------HRHSGASART----TPATGE-----QSPGARS-----RHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPP--------AAPLSVT---------------------------------------------------------------------------------------------------------------PNPNTTSLPAPATPAEGEEPSTSG---------------TQQLP-----------------AAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTT---------------------------WER--PLPPGWE-KRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQ------------------------SQRNQLQGAMQHFSQRFLYQ----------------------------------------------------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG---------------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQG--SP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAYDRSFRWKYHQF-RFLCHSNALPS--HVKISVSRQTLFEDSFQQIMNMKPYD-LRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNN-YCLQINP-ASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEEC-GLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYR-HYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0H4-1", "uniprot_id": "SUDX_DROME", "id": "Q9Y0H4-1", "name": "E3 ubiquitin-protein ligase Su(dx)", "aln": "-----------------------------------------------------------------------------------------------MADGNGLPAGAASGGMEAG----------------------------------------------------------------------QTVNGAGSASPTPTSSSGAGASGSANQG----------------------------------------------------------------YHQLSVTIEEASLRNNGFLKPNPYVELLID-------------------------------------------------------------------------------------------------------------------------------SKSKRKTDLVKNSYL------------PKWNEEFTVLIT-----------------------PNST---------------------------------LHFKVLDHS----------------------------------------------------SFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMR-------------------------------LRSSSGNSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAG-----------------------------------------------------------------------------------------------------------GGAAVGPPGVAGPPIEQPGVGLPV---------------SQSTDP-------------QLQTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTY---------------------------WEKPTPLPPGWE-IRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQ------------------------GQR---AHVVSQGNQRYLYSQQQQQPTA------------------------------------------VTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVS-----------------LINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAYERSFRWKLSQF-RYLCQSNALPS--HIKITVTRQTLFEDSYHQIMRLPAYE-LRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNN-YSLQINP-ASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDEC-GLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYR-HYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K4P8-1", "uniprot_id": "HECW1_MOUSE", "id": "Q8K4P8-1", "name": "E3 ubiquitin-protein ligase HECW1", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEP-LRYSYNPDQFHNIDIRNGAHD--AITIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIGEVSSENFLDYKNRGVNGSHRGQIIWKIDASSYFVESETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKGIGSEETAQSQGSRR---------------------------------------------------------------LISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSTIIGNTVNPIWQAEH-------------------------------------------------------------------------------------FSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVS----------------YTLGRRLPTDHVSG----------------------QLQFRFEITSSIHADDEEISLSAEPESS------------------------AETQDSIMNSMVGNSNGEPSGDATEFCKDAKPESPSEGNGVNSSENQNQEHAGPVEEAAGAMEARDGSNVSEAPEEPGELQDPEQHDTQPTLSAEEVAEGLPLDEDSPSSLLPEENTALGSK---VEEETVPENGAREEEMQKGKDEEEEEEDVSTLEQGEPGLELRVSVRKKSRPCSLPVSELETVIASACGDAETPRTHYIRIHTLLHSMPSAQRGSTTEEEDGLEEESTLKESSEKDGLSEVDTIAADPQSMEDG--ESDGATLCMAPSDCSGGHFSSLSKGIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYSTSCYSSSCYSSSCYSSSCYN-----GNNRFASHTRFSSVDSAKISESTVFSS---------QEDEEEENSAFESVPDSVQSPELDPESTNGAGPWQDELAAPGGNAARSTEGLESPMAGPSNRREGECPILHNSQPISQLPSLRPEHHHYPTIDEPLPPNWE-ARIDSHGRVFYVDHINRTTTWQRPSMAPTPDGMIRSGS---------------------VHQMEQLNRRYQNIQRTMATERAEEDSGNQNSEQIPDGGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQ-KVTLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDHQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASE---------------VSRNRGASLLARPGHS-------------------------------------LIAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLDKLSCDADLVILLSLFEEEIMSYVPLQSAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDT-YTVQISP-MSAFVENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALLRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP0-1", "uniprot_id": "A0A8I5ZQP0_RAT", "id": "A0A8I5ZQP0-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEP-LRYSYNPDQFHNIDIRNGAHD--GITIPRSTSDTDLVTSDSRSTLMVSSSYYSIGYSQDLVIHWDIKEEVDAGDWIGMYLIGEVSSENFLDYKNRGVNGSHRGQIIWKIDASSYFVESETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKGIGSEETVQSQGNRR---------------------------------------------------------------LISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSTIIGNTVNPIWQAEH-------------------------------------------------------------------------------------FSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVS----------------YTLGRRLPTDHVSG----------------------HLQFRFEITSSIHADDEEISLNAEPES-------------------------AEVQDSVMNSVVENSSGEPPGDAAEFLKDLKPEAPSEEDGVRGSENENREHARPVEEAAGAMETRDDSKFSEGPEEVGELQDPEQHDTQPTLSAEEVAERLPLGEGCPPSLLPEESTALGSK---AEEEAIPENGAGEEEMQEKGKDEEEEEGVSALEQGEPGLELRASVRKKSRPCSLPVSELETVIASACGEAETPRTHYIRIHTLLHSMPSAQRGSTTEEEDAMEEESTLKESSEKDGLSEVDTIAADPQSMEDG--ENNGATLCMASSDCSGGHFSNLSKSIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYSTSCYSSSCYSSSCYSSSCYN-----GNNRFASHTRFSSVDSAKISESTVFSS---------QEDEEEENSAFESVPDSVQSPELDPESTNGAGPWQDELAAPGGNAARTTEGLDSPMAGPSNRREGDCPMLHNSQPISQLPSLRPEHHHYPTIDEPLPPNWE-ARIDSHGRVFYVDHVNRTTTWQRPSMAPTPDGMIRSGS---------------------VHQMEQLNRRYQNIQRTIATERSEEDSGNQSCEQIPDGGAGGGG-SDSEAESSQSNLDLRREGSLSPVNSQ-KVTLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDHQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASE---------------VSRNRGASLLARPGHS-------------------------------------LIAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQSAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDT-YTVQISP-MSAFVENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSTLYEKLLTAVEETSTFGLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76N89-1", "uniprot_id": "HECW1_HUMAN", "id": "Q76N89-1", "name": "E3 ubiquitin-protein ligase HECW1", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEP-LRYSYNPDQFHNMDLRGGPHD--GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRR---------------------------------------------------------------LISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQ-------------------------------------------------------------------------------------FSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVS----------------YTLGRRLPTDHVSG----------------------QLQFRFEITSSIHPDDEEISLSTEPES-------------------------AQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEK---EQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLAN--GAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCY-NGNRFASHTRFSSVDSAKISESTVFSS---------QDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWE-ARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGS---------------------IQQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGG-SDSEAESSQSSLDLRREGSLSPVNSQ-KITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASE---------------VSRNRGASLLARPGHS-------------------------------------LVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDT-YTVQISP-MSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QG29-1", "uniprot_id": "A0A8M9QG29_DANRE", "id": "A0A8M9QG29-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MNEEVMIHRQVILTQNLYQSRFLGLAAMASPSRASQGRRRCKDP-IRHSFNPEQFPNVDFQNGVAEDLAAAVLRSTSDTDLLTSHCRSTLTVSTSSYTIGQTQDITLSWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHKGQIIWKIEASSYFVEPETKICFKYYHGVSGALRATTPCVTVKNPSAPVFKPVATDDVPQSQGRRR---------------------------------------------------------------LISFSLSDFQATGLKKGMFFNPDPYLKIAIHPGKHSIFPALPHHGQEKRSGIVCNTINPVWQRER-------------------------------------------------------------------------------------FNFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLEKHAIGDRVVS----------------YTLGRRLPTEHVSG----------------------QLQFRFEITSSIHPDDEDMSLSTEQPV-----------------------------------AAAEAQAQPQAEDTMSLDLGAPELPLDGDTASVEMPMDVESGQSCAAEADVIEEECLEEEQQEGEAAAAAAAMEQSETN----AEETTQVLDPINGAEE-EEAENNCAFAEE--------SSDARAGEEDEAISDPQPASEEPDADLEEDCS-LRIRTTPRRKPRPCSLPVSELETVIASACGEPETPRSHYIRIHHLLHSLPATQP--QTGDSAGPEPDRPMG-VEEEDEEEEEEGVTLEDHALTPN------GPRRTLPRSRSHERLSDLIQ----MLDGDGHP-LGAEG----QTGNQRSPDLSPVACCSHMSP-----------------------------RASGPIRAQSLDSARRSESTVFSS---------QDDEDEMEQPNGILGSETETEQGAQCREPGDGSCQWEEAPDSHVQSPHGIVGNGEVAGPSGRRE--CPLPCNHPAVSQLPALRPDPHHYPTIDEPLPPNWE-ARIDSHGRVFYVDHINRTTTWQRPTSAATPDGLRRSGS---------------------VQQMEQLNRRYQTIQRTMATERREEESGSPRNDRTAN----------TETDSPLQTNELRRDTSCSPGHCQ-KITLLLQSPAVKFITHPEFFTVLHANYGAYRMFTNSSCLKHMVLKIRRDARNFERYQHNRDLVTFLNRFADAQLELPRGWEIKTDPQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASE---------------VSRTRGVSLLARPGNS-------------------------------------LVAAIRNQSQQEPVPLAYNDKIVAFLRQPNIFEVLQERQPSFARNHSLKDKVHHIRTEGTQRLEKLSCDADLVMLLSLFEEDIMSYVPLAS-FHPGFNFSPRCSPGSSPQNSPGFLERTPLVPACCLSGESSPGTQRARAPAPYRRDFEAKLRNFYRKLEAKGYGQGPGKIKLIVRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDT-YTVQISP-MSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPTDLSDLEYLDEEFHQSLQWMKENDITD--VLDLTFTVNEEVFGQVTERELKSGGTNVQVTEKNKKEYIERMVKWRVERGVVQQTQALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHIVIRWFWGAVERFNNEQRLRLLQFVTGTSSVPYEGFTALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYTMLYEKLLIAVEETSTFGLE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9P2P5-1", "uniprot_id": "HECW2_HUMAN", "id": "Q9P2P5-1", "name": "E3 ubiquitin-protein ligase HECW2", "aln": "---------------------------MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPEN--MTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRK---------------------------------------------------------------LVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREK-------------------------------------------------------------------------------------YSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLS----------------YNLGRRLPADHVSG----------------------YLQFKVEVTSSVHEDASPEAVGTILGV----------------------------------NSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTD-------TRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQ-VSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWE-ARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNS---------------------IQQMEQLNRRYQSIRRTMTNERPEENTNAIDG-------------AGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGE---------------DSRHAGPPVLPRPSST-------------------------------------FNTVSRPQYQ-DMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRAN------------------ARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDT-YTVQISP-MSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHD--ILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W326-1", "uniprot_id": "Q9W326_DROME", "id": "Q9W326-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "---------------------------MEPPAAPVPLQPLAASSACLADRSPVDPIAVRLQQEEQAE-----GDDEEEEEEEEDDDDDPKEEEAFYEARNGNESDELEQAFQSALTLTNDVHVSVSEVEEHEPPLASRNQEVAEVEEQQQQLGACALPQPSEASLTGSKETREPRHHQTLLSTKSCETPANNATLSPTNSYNGSIGSDGGSS---------------------------------------------------------------VGGGARRKSWTLSPQSGGSTPLSGAKKKTKTGAPTTTLSNANGDGFNLWVARECFETVPAEMVDT-------------------------------------------------------------------------------------LSMAEVDEEVDEEEDEEAAAVESLLGAAAALQASAHVQRRQQQQHHQHLRQPSPPQH-----------RPLERSWPPRAVGR----------------------DLKLQGDVFQFDILDTDERLAEEMAQG------------------------------------SGSSNNSPLATPPVRFKPLLKKKIGPDSYINTISTQKVPVHQSYEFPTFPSSSAVGSSSSSPNSLQFPYLRQHR----------PLTRALSNGKASSSEEQASPRLLLSPK-------------------------RPRSPPSGCSTRSASPLDISLSPEQHSPTRGRGVGG---ALQDAVPPGTPTFHGQRPQQRLLKRVGGGAGAGATGGATGSPLVCPPTPTHHARRHARLQAVTANSSLASGG-------------------------------------------------------------------------------------------------------AIPSDPPAVSSQLDYIYLQ------------DGGQEQGQEQSDEVVHISSTRLPSIPERSAAAAAAAAAAAAGAALMEPGTGTVSGSSGAG--------------------------AAGEPPLPPAWE-ARMDSHGRIFYIDHTTRTTSWQRPGAAPSGGPAGREQ-----------------------HHRQQLDRRYQSIRRTITNESR------------------------AAQLYNLPTSANSNANSTAPAAPP---PATAIHPAILMLCRPDFYSLLHTNEAALAIYNRNAALKHMVMRIRRDPPCFQRYQYNKDLVALVNTFAQMSRELPSCWETKLDQSGKQFFIDHQHRRTSFMDPRLPVECPRVVRHRQQHSQQQSSVGYYYPDLVDGNCLSATSGHINASPASSVSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTTSAISCALNADRSAYGAAGMASAGATAAGYEDVPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPALERLGHDLQLTILLSLFEQEIMGFVPIEE---------------RSPQGSPVLNSRMP-----------------QRAPPPFRRDFEAKLRSFYRKLESKGYGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDT-YTVQVSP-LSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGIE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *: : : . :* : : ** ** : . ::::*: : * : *** : * :. * * : .: : * ::* ::. : : : :* : * ****.* :**:*:*:*:*::** * ****: : * :*:. . : :* * **. .:.: * :: * .:** :* : *:* :* * :.*: *: :*. * : * : :*. :** .* . :.: ** **: .**. : :* :: ** .: : ** .***::: * ::* **: : *: * : *** : . * * *****.***. :* ** * ** * : * ::: * :*::******:*** * : :** *:* : * ", "identical_positions": 118, "similar_positions": 118, "identity": "6.08%" }, { "cls_id": "homologset.agr.SGD:S000000928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYU7-1", "uniprot_id": "NSA2_RAT", "id": "Q9QYU7-1", "name": "Ribosome biogenesis protein NSA2 homolog", "aln": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKDDEKTPQG-AVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWESPLPKVRAQGETELLKVIRTGKRKKKAWRRMVTKVCFVGDGFTRKPPKYEKFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR47-1", "uniprot_id": "NSA2_MOUSE", "id": "Q9CR47-1", "name": "Ribosome biogenesis protein NSA2 homolog", "aln": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKDDEKTPQG-AVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95478-1", "uniprot_id": "NSA2_HUMAN", "id": "O95478-1", "name": "Ribosome biogenesis protein NSA2 homolog", "aln": "MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQG-AVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76994-1", "uniprot_id": "O76994_DROME", "id": "O76994-1", "name": "Ribosome biogenesis protein NSA2 homolog", "aln": "MPQNEYMERHRKLYGRRLDYEERKRKKEARLPKDRARKARKLRGIKAKLFNKERRNEKIQIKKKIQAHEEKKVK-KQEEKVEDG-ALPHYLLDRGIQSSAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSDAEVFKVLKTGKTKRKAWKRMVTKVTFVGENFTRKPPKFERFIRPMGLRMKKAHVTHPELKATFNLPIIGVKKNPSSPMFTSLGVITKGTVIEVNISELGLVTQTGKVVWGKYAQVTNNPENDGVINAVLLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40078-1", "uniprot_id": "NSA2_YEAST", "id": "P40078-1", "name": "Ribosome biogenesis protein NSA2", "aln": "MPQNDYIERHIKQHGKRLDHEERKRKREARESHKISERAQKLTGWKGKQFAKKRYAEKVSMRKKIKAHEQSKVKGSSKPLDTDGDALPTYLLDREQNNTAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKSRSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTAGGKVVWGKYAQVTNEPDRDGCVNAVLLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:* * * :* ***:.*:***:*.* .:. :.:*:*: * *.* : *:* **:.::*.*: **: :.* ... :* *:* ***** :. **.:*. ***** ***.*:. *:****. .: *::**::*** : *:*:**:** ***:.***:* * *::*** .** ***:****** .*. ***:.*****.**::* ***:****:****:****:** ***:*********:*:.** :******", "identical_positions": 142, "similar_positions": 76, "identity": "54.41%" }, { "cls_id": "homologset.agr.SGD:S000000929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL94-1", "uniprot_id": "A0ABK0LL94_RAT", "id": "A0ABK0LL94-1", "name": "", "aln": "MMLSWVSFRSPSSFRFARSRSMMLSWVSFRSPSSFRFARSRSMRTFFSCSRDPSSWQREEPAMNHKEVLESEVSSSITLLKNLQEQVMAVTAQVQALTAKVRAGAYSTEKGLSLLEVKDQLLLMYLMDLSHLILDKASGGSLQ--GHPAVLRLVEIRTVLEK-LRPLDQKLKYQIDKLVKTAVTGSLSENDPLRFKPHPSNMMSKLS-----------------SEDEEENEA-----------------------EEDQSEASGKKSVKGASKKYVPPRLVPVHYD--ETEAEREQKRLEKAKRRALSSSVIRELKEQYSDAP--------EEIRD-VRHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGLRRRASAMSSQLHSLT-HFSDISALTGGTAHLDEDQNPVKKRKKMPKKGRKKKGFRRRW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB96-1", "uniprot_id": "NGDN_MOUSE", "id": "Q9DB96-1", "name": "Neuroguidin", "aln": "--------------------------------------------------------------MAAPEVLESDVSSSITLLKNLQEQVMAVTAQIQALTTKVRAGTYSTEKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQ--GHPAVLRLVEIRTVLEK-LRPLDQKLKYQIDKLVKTAVTGSLSENDPLRFKPHPSNMVSKLS-----------------SEDEEESEA-----------------------EEGQSEASGKKSAKGSAKKYVPPRLVPVHYD--ETEAEREQKRLEKAKRRALSSSVIRELKEQYSDAP--------EEIRD-ARHPHVTRQSQEDQHRVNYEESMMVRLSVSKREKGLRRRASAMSSQLHSLT-HFSDISALTGGTAHLDEDQNPVKKRKKLPKKGRKKKGFRRRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEJ9-1", "uniprot_id": "NGDN_HUMAN", "id": "Q8NEJ9-1", "name": "Neuroguidin", "aln": "--------------------------------------------------------------MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLLMYLMDLTHLILDKASGGSLQ--GHDAVLRLVEIRTVLEK-LRPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLS-----------------SEDEEEDEA-----------------------EDDQSEASGKKSVKGVSKKYVPPRLVPVHYD--ETEAEREKKRLERAKRRALSSSVIRELKEQYSDAP--------EEIRD-ARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSLT-HFSDISALTGGTVHLDEDQNPIKKRKKIPQKGRKKKGFRRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFJ1-1", "uniprot_id": "NGDN_DANRE", "id": "Q6PFJ1-1", "name": "Neuroguidin", "aln": "----------------------------------------------------------MAATAVGNDVIDRDLPTAVRLLNSLTEQIVSVTSHVRELIKKVREKAYQTSKGLSFLDLRYHLLLFYLQDITHLISLKTEGESLK--DNSAIHRLVTIRTVLEK-MRPLDQKLKYQIDKLVRTAVTGSLSENDPLHFRPNPQSLVSKLS-----------------ESEDSDDDG-----------------------VGGKTKE--QKEPSGG-RRYVPPRIAPMHYDGDLTEADRQKERVEKQKRAALRSSVIQELRQQYSDAP--------EEIRD-RRDFQTDRQGREELNRKNYEESMMVRLSTTRDQKLRKRGMMGMTSQLSNIT-RFSDITALTGG--EVQDIGNPKPKKKKIIKKG-KKKVFRKRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMM7-1", "uniprot_id": "Q9VMM7_DROME", "id": "Q9VMM7-1", "name": "Neuroguidin", "aln": "---------------------------------------------------------MVQALDYDCEAQGQDIPQAIQLLGEMNSNVKQVTDLVEGMLQRVKRGELTTEYGLSFLEVKYHMLLDYLINLTYVVLRKCSGETIE--GDPSIERLIEIRTVLEK-IRPIDHKLRYQIDKLVKTATTGVSSSTDPILYKPNPDDMMSSAGGAGRDEDDGEDDSDEEDEDDDEEDED-----------------------EAGAAKMPRKAATAGKSGVYVPPRIKPVYYDGDERDADKEKKALDRAKKRAITSSMLQDLKEEYLDAP--------TEISSGSRAQQMLSQAQKE--KQEYEETYLMRLPVTKAEKHRQRKLTTLGTLGDEILGEISRESALRGD----GSKKRKLAKKGKGKKRGGKKRKFH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40079-1", "uniprot_id": "LCP5_YEAST", "id": "P40079-1", "name": "U3 small nucleolar ribonucleoprotein protein LCP5", "aln": "------------------------------------------------------MSELNALLKDINGSLTATSESLERLSGIYSNSATDEIPESNQLHEHLFYDAKKPAEKVSLLSLKNGSMLGYINSLLMLIGNRLDDECKDPSAMDARERSIQHRVVLERGVKPLEKKLAYQLDKLTRAYVKMEKEYKDAEKRALEKSTLVNHSG--------------NDDSEDDESSEDEIAYRPNTSGIINTNKKSSAYRVEETAKQENGEENDDNETGVYKPPKITAVLPPQQTHFEDRFDAREHKDRSNKSRMQAMEEYIRESSDQPDWSASIGADIVNHGRGGIKSLRDTEKERRVTSFEEDNFTRLNITNKAEKRKQKQRERNARMNVIG---GEDFGIFSSKRKLEDSTSRRGAKKTRSAWDRAQRRL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. . : :: . :*:*.:: :* *: .: :: : .. . : * : *.***: ::*:::** **:*** :: .. . .*. . . ::. . ..::...: : : . * **:: .: :: . .: : . :.: .: * * : : : .:: .:** : ** :. : :: : : . .: .. . : . . :: : ", "identical_positions": 28, "similar_positions": 100, "identity": "6.48%" }, { "cls_id": "homologset.agr.SGD:S000000931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4V2C3-1", "uniprot_id": "A4V2C3_DROME", "id": "A4V2C3-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "MDLTDPLLITKSQQVNSQEVDFQKKTEDTFPSKFHKNKASCGLLAVNESRCTDHQLQCENNIVGLSLETQIAENSSINVSRELKPHDHTFPKDKQTFKQISDELRKSYENINKVQNIKKSQSVENFEKCSEINLANKCLYTNLNTSPKERNALDKQAMFIKFHSLELCTDKVCSLHIHENFCTDIHKCVVDSESNKPNKMKKCLDYESVKRYPCKVSNEPPQHNTASKPQILYETRPIYPNVPYSPYSTPFSSPRSSRRKPAFRESRRISIDKSGSFLQLNQYRLMEQIGQGSYGLVKLAYSEEDSTHYAMKILSKKRLLRQAGLMRR----GPRKATS-------PLDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIPTDNPLSEKR---------AWSIFRESLLGLEYYTMLSSSAISLKRIFVYTVHHQKIIHADIKPGNLLLTEFGHVKIADLGVCNEFLGDDATISN--------GSTAGTPAFRAPETLI----------PGQNEYCG----RAADVWALGATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVTEN-------------LKSCIVQMLEKNPTQRITIPQLKTSKWVTSDGDYPLPTEE------------------ENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKK--------------------------------------------------------------------------------HSFGNPFVKGCSGTSSSLAGCSRIERFIRAGRSNS---------------------APGSYHMSTARQPSSDTLLPSLME-------------------HCSTQCNEGTHSFDY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2BJ77-1", "uniprot_id": "A0A8M2BJ77_DANRE", "id": "A0A8M2BJ77-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "-----------------------------------------------------------------MVMAMSSGPGGVRVERDPD----------------------------------SSQTAEMTDRMSVMSLG------------------------------------------------------PDSSS-------------SVLKNGMGVKKAQPKRPHLSGRKMSLQERGTY------------MSSRIARQP--TIESKRVSISDSQDCIQLNQYKLKSEIGKGSYGVVKLAYNEDDDKYYAMKVVSKKKLMKQYGFPRRPPPRGPKAAQGEQPKVLGPLERVYQEIAILKKLDHLNIVKLVEVLDDPAEDNLHMVFELMQKGPVMEVPSDSPFSEDQ---------ARHYFRDIVLGIEY------------------LHYQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDALLS----------STAGTPAFMAPETLS----------DNRQSFSG----KALDVWAMGVTLYCFVYGKCPFIDEYILALHNKIKSKVVEFPDTPTVSEG-------------LKSLVSRMLDKNPDTRITIPEIKVDPWVTQDGKDPLPLEE------------------EHCTVVEVTEEEVQNSVKFVPSLSAVILVKAMLRK--------------------------------------------------------------------------------RSFGNPFECPSR----------------REERSMS---------------------APGSLLMDSWPFRPSFKLQPSLRK-------------------GSSGEAPREAELEDLHEDEPPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38990-1", "uniprot_id": "SAK1_YEAST", "id": "P38990-1", "name": "SNF1-activating kinase 1", "aln": "-------------------------------------------MDRSDKKVNVEEVNVPSNLQIELEKSGTSSSVSLRSPTKSSATN---------------------------LAGMAEGARDNASIASSS---------------------------------------------------------VDSLN------------MLLERQRVRQLNHPQHQQHISSSLAKTPTTTSS-----------FCSSGSSKNKVKETNRISLTYDPVSKRKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIK---SSKISEN---------DKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEY------------------LHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEMAKDLLLKLLEKNPQKRMTIPAIKKHPFVSWDFDHVPENDEKLLSSVLEQKLRFQCNQTDQFEPISISKHELKNAVSGVGKKIKESVLKSIPLKDPSDLSNKNYLHPTETTRGRGDANVIVSEGSVLSNIKELSANDGCLNTDSDTNININDDDHYSGDDNDGHLTKRELERELNKFDDKHEAGNMVNLPINSSFASLDSFYIDNFAMARMGMSSPEAGDSVSSVPNLPSAPSSTRLGRSPVFSGVTNQPSPIRPVLPQQKSSFCATGRYDKSHNSLLRNSSSHLTSYNSGRPSSRTGRMNSRNQNLPKIPNSLSKISTTKLTELRVPKDSEIPSPAKNPNADRLRRFPVKKNTKTPAIKDPPRININSSDKSGSKNSPIKSLYQRMKQSKDNSKTFEVRRGNFFSHFNGDDDDSSSQSSVTSSGSESDSELSSTSSSCTSGTQSRNSSNNNAYSETESLPFEFGVDSEDGSGVLLRDLPNEDQIRPFLDIQPCRRMKVKSSLNLEPPSVSSSSSSSSDEDELILNVGTAGHRRRHNSSKLSELSNSPQKGSNNFMYSNGSVHDSETTITPQNMDDLTLHQALSRSQPISKPGPLVLPKRLDQKKATTETSNLTDIVEFNGNNDHRKDKNFDKVLYSRDLLKDALSSTNAGRRRSIPSNKIRGRKDASITMSTNVGNDEHARNTSCHGDKGQENGAIKQRTHERSRSLTVAELNEEKRRSALP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:. . . . : : . * ** . : : : :: * *. ::. : :: . . ** *.: .::*:*.:* **** . .. *:*::.::. :: : ..: : . ::: :***::** .* ::*:*:***** . .:::*:* .:* * *.* *: : : :* :**:** :*:* *:* ****.***: * ***:*:**. . :: * .*.***** *** .: : * *:**:*.***.:::* **: : *.:** .. ::** : .. *. : ::*:*** *:*** :* :*: * . :* :: :.: ..::.. * : . ::*:: * ..*.: . : : **.* :. .. . ** . * :. . ", "identical_positions": 109, "similar_positions": 157, "identity": "8.25%" }, { "cls_id": "homologset.agr.SGD:S000000933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62854-1", "uniprot_id": "RS26_HUMAN", "id": "P62854-1", "name": "Small ribosomal subunit protein eS26", "aln": "---------------------------------------MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP--PRF-RPAGAAPRPPPKPM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62856-1", "uniprot_id": "RS26_RAT", "id": "P62856-1", "name": "Small ribosomal subunit protein eS26", "aln": "---------------------------------------MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP--PRF-RPAGAAPRPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62855-1", "uniprot_id": "RS26_MOUSE", "id": "P62855-1", "name": "Small ribosomal subunit protein eS26", "aln": "---------------------------------------MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP--PRF-RPAGAAPRPPPKPM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JNZ5-1", "uniprot_id": "RS26L_HUMAN", "id": "Q5JNZ5-1", "name": "Putative ribosomal protein eS26-like", "aln": "---------------------------------------MTKKRRNNSHAKKGRGHVQPIRCTNCVRCVPTDKAIKKFVIRNIVEAAAVRDISEVSVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREACKDRTPP--PRF-RPAGAAPRPPPKPM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZY57-1", "uniprot_id": "A0A8I5ZY57_RAT", "id": "A0A8I5ZY57-1", "name": "40S ribosomal protein S26", "aln": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPP--PRF-RPSGAAPQPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JVP7-1", "uniprot_id": "A0A0G2JVP7_RAT", "id": "A0A0G2JVP7-1", "name": "40S ribosomal protein S26", "aln": "---------------------------------------MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSP--PRF-RPAGAAPRPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13008-1", "uniprot_id": "RS26_DROME", "id": "P13008-1", "name": "Small ribosomal subunit protein eS26", "aln": "---------------------------------------MTKKRRNGGRNKHNRGHVKPVRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDITEASIWDSYVLPKLYAKLHYCVSCAIHSKVVRNRSREARRIRTPP--LRS-FPKDMARNNQNRK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39939-1", "uniprot_id": "RS26B_YEAST", "id": "P39939-1", "name": "Small ribosomal subunit protein eS26B", "aln": "---------------------------------------MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRDNKVSPAAAAKKAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**: ...: *:.:***:*: *.** .:*.***** :.* **:*:****.::*. :: *. ** * ******* ***:::: :* * : ::.* * : : ", "identical_positions": 43, "similar_positions": 37, "identity": "27.22%" }, { "cls_id": "homologset.agr.SGD:S000000935", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62138-1", "uniprot_id": "PP1A_RAT", "id": "P62138-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR----NSAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62137-1", "uniprot_id": "PP1A_MOUSE", "id": "P62137-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR----NSAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62136-1", "uniprot_id": "PP1A_HUMAN", "id": "P62136-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR----NSAKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63087-1", "uniprot_id": "PP1G_MOUSE", "id": "P63087-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGM--ITKQAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63088-1", "uniprot_id": "PP1G_RAT", "id": "P63088-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGM--ITKQAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36873-1", "uniprot_id": "PP1G_HUMAN", "id": "P36873-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGM--ITKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48461-1", "uniprot_id": "PP11_DROME", "id": "P48461-1", "name": "Serine/threonine-protein phosphatase alpha-1 isoform", "aln": "MS--DIMNIDSIISRLLEVRGARPGKNVQLSESEIRSLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRRFVYPNF---GSSGRPLTPPRGA--NNKNKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12982-1", "uniprot_id": "PP12_DROME", "id": "P12982-1", "name": "Serine/threonine-protein phosphatase alpha-2 isoform", "aln": "MG--DVMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKR-----------------------------KK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05547-1", "uniprot_id": "PP13_DROME", "id": "Q05547-1", "name": "Serine/threonine-protein phosphatase alpha-3 isoform", "aln": "MA--EVLNLESIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREILLAQPILLELEAPLKICGDIHGQYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTIGWGENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQILKPVEKR-----------------------------KK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "id": "P32598-1", "name": "Serine/threonine-protein phosphatase PP1-2", "aln": "MD-SQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKS------------------LPRQA--GGRKKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P62142-1", "uniprot_id": "PP1B_RAT", "id": "P62142-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MA-DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGG---LNSGRPVTPPRTA---NPPKKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62140-1", "uniprot_id": "PP1B_HUMAN", "id": "P62140-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MA-DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGG---LNSGRPVTPPRTA---NPPKKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62141-1", "uniprot_id": "PP1B_MOUSE", "id": "P62141-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MA-DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGG---LNSGRPVTPPRTA---NPPKKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N207-1", "uniprot_id": "A0A8M1N207_DANRE", "id": "A0A8M1N207-1", "name": "Serine/threonine-protein phosphatase", "aln": "MA-EGELNVDSLISRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDESLMCSFQILKPSEKKAKYQYSG---VNSGRPVTPPRTA---QAPKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48462-1", "uniprot_id": "PP1B_DROME", "id": "P48462-1", "name": "Serine/threonine-protein phosphatase beta isoform", "aln": "MG-DFDLNVDSLIQRLLEMRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAKYLYSG---MNSSRPTTPQRSAPMLATNKKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::::.:* ****::..:.*: *:: * *:* ** *:*.*:: **********: ********* **********:** :***************************:*.****:***********************:.:**************:.**:****** ******** .******:*****:** ************** **.*********** :** :**::::::****************::* ******************.**:**::*:******** :* * ", "identical_positions": 226, "similar_positions": 52, "identity": "67.66%" }, { "cls_id": "homologset.agr.SGD:S000000936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86V88-1", "uniprot_id": "MGDP1_HUMAN", "id": "Q86V88-1", "name": "Magnesium-dependent phosphatase 1", "aln": "MARLPKLAVFDLDYTLWPFWVDTHVDPPFH--KSSDG---TVRDRRGQDVRLYPEVPEVLKRLQSLGVPGAAASRTSEIEGANQLLELFDLF---------RYFVHREIYPGSKITHFER----LQQKTGIPFSQMIFFDDERRNIVDVSKLGVT------CIHIQNGMN-LQTLSQGLETFAKAQTGPLRSSLEESPFEA-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D967-1", "uniprot_id": "MGDP1_MOUSE", "id": "Q9D967-1", "name": "Magnesium-dependent phosphatase 1", "aln": "MTRLPKLAVFDLDYTLWPFWVDTHVDPPFH--KSSDG---TVRDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLG---------KYFIQREIYPGSKVTHFER----LHHKTGVPFSQMVFFDDENRNIIDVGRLGVT------CIHIRDGMS-LQTLTQGLETFAKAQAGL-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4U3-1", "uniprot_id": "D4A4U3_RAT", "id": "D4A4U3-1", "name": "Magnesium-dependent phosphatase 1", "aln": "MTRLPKLAVFDLDYTLWPFWVDTHVDPPFH--KSSDG---TVRDRRGQDIRLYPEVPEILGRLQSLGVPVAAASRTSEIEGANQLLELFDLG---------KYFIQREIYPGSKVTHFER----LRNKTGVPFSQMIFFDDENRNIIDVGKLGTESLLRGRYLHSHTGWNESSNVNSRIRDICKSPSWTLRSGPVDKPHYSVKLKRNQGSLVRSTCNVLKCPRVTIRVLSQYGLFPFFFSFLLFFFKDLFIYYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40081-1", "uniprot_id": "MGDP1_YEAST", "id": "P40081-1", "name": "Putative magnesium-dependent phosphatase YER134C", "aln": "MTGYPDVAAFDLDYTIWPCYCDTHLHGPFKPVKSSNGEVLTIICRDGYELTIYKDIPRILGDLKDNGVKLMTASRTWAPEIAQEILKIFKVKYAGVVTPLANLFDEFQWGERSKIGHLRDGLKDLYNTSDLKSKKICLFDDESRNK-EVEKYGVK------FVYVRDPEN-----GPSWKLYQDYLSGKV----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.:*.******:** : ***:. **: ***:* *: * * :: :* ::*.:* *:. ** :**** : *:::*::*.: . * . : **: *:. * :.:.: .:: :**** ** :* : *. :: : . . . : ", "identical_positions": 49, "similar_positions": 54, "identity": "19.29%" }, { "cls_id": "homologset.agr.SGD:S000000938", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50399-1", "uniprot_id": "GDIB_RAT", "id": "P50399-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPAS----MGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61598-1", "uniprot_id": "GDIB_MOUSE", "id": "Q61598-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPAS----MGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50395-1", "uniprot_id": "GDIB_HUMAN", "id": "P50395-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50396-1", "uniprot_id": "GDIA_MOUSE", "id": "P50396-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50398-1", "uniprot_id": "GDIA_RAT", "id": "P50398-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31150-1", "uniprot_id": "GDIA_HUMAN", "id": "P31150-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLB7-1", "uniprot_id": "Q9VLB7_DROME", "id": "Q9VLB7-1", "name": "Rab GDP dissociation inhibitor", "aln": "-----MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYGLE-PPGER----FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVPVDQKEALASDLMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKNTQDFTGHALALFRDDEYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDKPIDEIVLGEGG-KVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGK-VIRCICILDHPVASTKDGLSTQIIIPQKQVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVETENPEVEIKPGLDLLEPIAQKFVTISDYLEPIDDGSESQIFISESYDATTHFETTCLDVLNIFKRGTGETFDFSKIKHELGDEEQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39958-1", "uniprot_id": "GDI1_YEAST", "id": "P39958-1", "name": "Rab GDP-dissociation inhibitor", "aln": "MDQETIDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVT-LSQLYEKFKQNPISKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDFKQVSGSYVFKQGKIYKVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNTMDEVYYKFGLGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKSTGQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLAIISTIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESMTDDVKDIYFRVTGHPLVLKQRQEQEKQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :**.******:.******::**.******:*:: :****::*:* *.:*:::: . :*:.****************:*.::*:.* ****::** .**:*:* *** *** : **::* ***:*****:::** :: .: *.* * :..* . .* :* **.*.:.. :* **::**: *:**::*. :..** **.:*:***********:***********************:.*::::: :. *. **:: :. : .**:*. :: .. *: *** ****.**: .*.:. * ******.*:.*******.::* :*:*.::* ::.: ** :** .*. *:.*.:.** ** :**: *:: * : * ..::: * :***::***: *: :*: * :* : :.: :.: : ", "identical_positions": 201, "similar_positions": 153, "identity": "43.79%" }, { "cls_id": "homologset.agr.SGD:S000000941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0E6-1", "uniprot_id": "RPAP2_RAT", "id": "Q5I0E6-1", "name": "RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPYSLGPSARASSTHR-VATGTKQTSALKRRDASKRQAELEAALQRKVESERRAVRLVEQLLEENITEE-FLKECGMFITPAHYSDVVDERAIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITE----RKSFCSNFCYKASKFFEAQIPKTPVWVREEERPPEFQLLKKGQSGCSGEVVQFFRDAVTAADVDAYGAFDAQCEPASSSTWSERASDERASDEEGPGFVSSLLP--------GNRPKAVGTKPQPHRQSSTVKKKAAQKMTSKHG--EQTVSEVTEQLSNCRLDS--QEKVATCKLPAKKENTQISSPGPLCDRLNTSTVSENKHSVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVQVRPEVAKANLLRVLKDTLTEWKTDETLKFLYGQDHGSVCLQPSAASGPDEELDEDDISC----------QAQNTLDETLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDSTKSQDSKENELQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLVQTFRLSNRNIIHKPVEWTLIAVVLLSLLTPILGIQKHSPKNVVFTQFIATLLTELHLKCEDLENLAMIFRTSC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC34-1", "uniprot_id": "RPAP2_MOUSE", "id": "Q8VC34-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPCSLGPSTRASSTHR-DATGTKQTRALKRGDASKRQAELEAAIQRKVEFERKAVRIVEQLLEENITEE-FLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITE----RKSFCSNFCYRASKFFETQIPKTPVWVREEERPPDFQLLKKGQSGSSGEVVQFFRDAVTAADVDGSGALEAQCDPASSSSWSERASD-----EEEQGFVSSLLP--------GNRPKAVDTRPQPHTKSSIMRKKAAQNVDSKEG--EQTVSEVTEQLDNCRLDS--QEKVATCKRPLKKESTQISSPGPLCDRFNTSAISEHKHGVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVHVRPEVAKANLLRVLSDTLTEWKTEETLKFLYGQNHDSVCLKPSSASEPDEELDEDDISCDPGSCGPALSQAQNTLDATLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDTTKSQDSKESVLQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLIQTFRLSNRNIIHKPVEWTLIAVVLLLLLTPILGIQKHSPKNVVFTQFIATLLTELHLKFEDLEKLTMIFRTSC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXW5-1", "uniprot_id": "RPAP2_HUMAN", "id": "Q8IXW5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2", "aln": "MADFAGPSSAGRKAGAPRCSR-KAAGTKQTSTLKQEDASKRKAELEAAVRKKIEFERKALHIVEQLLEENITEE-FLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITE----RKSFCSNFCYQASKFFEAQIPKTPVWVREEERHPDFQLLKEEQSGHSGEEVQLCSKAIKTSDIDNPSHFEKQYESSSSSTHSDSSSD------NEQDFVSSILP--------GNRPNSTNIRPQLHQKS-IMKKKAGHKANSKHKDKEQTVVDVTEQLGDCKLDS--QEKDATCELPLQKVNTQSSSNSTLPERLKASENSESEYSRSEITLVGISKKSAEHFKRKFAKSNQVSRSVSSSVQVCPEVGKRNLLKVLKETLIEWKTEETLRFLYGQNYASVCLKP-EASLVKEELDEDDIISDPDSHFPAWRESQNSLDESLPFRGSGTAIKPLPSYENLKKETEKLNLRIREFYRGRYVLGEETTKSQDSEE-------HDSTFPLIDSSSQNQIRKRIVLEKLSKVLPGLLVPLQITLGDIYTQLKNLVRTFRLTNRNIIHKPAEWTLIAMVLLSLLTPILGIQKHSQEGMVFTRFLDTLLEELHLKNEDLESLTIIFRTSCLPE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYY5-1", "uniprot_id": "RPAP2_DROME", "id": "A8DYY5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "aln": "--------------------------------MTTEKGEQLRQQLIAAVVKKRAAIARAHEIVVRLLEPGIPEP-EFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITE----RKKFCSGYCFKASEYIKSQVPTSPLWLRDRETRPSFQLLPRNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYH6-1", "uniprot_id": "RPAP2_DANRE", "id": "B0UYH6-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase rpap2", "aln": "-------MDAGEVTRKSRPSKSKKKGGKGTQAISAEDEAKRREAVKEQLRQKLELERKARQVVERLLEDSVTEE-FLMDCAWHITPANYKDTVEERSIAKLCGYPMCPNKLTNVPTQQYKISTKTNKVYDITE----RKCFCSNFCYKASKSFELQISKIPLWLRKEESPPEIKLMKQGDGGSSGQEIKLIDKPITEADIDNP----IEDIPESNKDLIQGENG-----DIEQDFVSSVVSNQHKQVHWGKLPKRDEVSEDAAEYSHSEHEQRINGENKDESESSQTPQPQKDTTDHPALEKNASEIEGTLELLNQDKSTQQEGENTSSSQP-ESDISVPVAGDLNITQVGMSKRSAAGLKG-LLKDHHKAKTASTAISQC-------LLERLRQAFIEWRTKETMIFLYGPDYASGMQLSTAGAWEEEQLDED-------------DLDEAEVGVRSAEGGPSRTSAPVPDVETLRKETEMLELRVREFYKGVCVLPEEVETAAVKETEHTQDSGKDPPLPLVDSHAQHQIQKRIVVEKLSHSLRDIVGPLRLTMSDVINDVNNLVRTFRFTNTNIIHKSPEWTLIAVVLLSVLTEVSPLLRESLASVSSLEYISCFMKELKLEDKDLHNLVLLFKPCVPIQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40084-1", "uniprot_id": "RTR1_YEAST", "id": "P40084-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR1", "aln": "-----------------------------MATIEDIKETALIPFQKHRQLSMHEAEVITLEIIGLLCDSECKDEKTLKYLGRFLTPDMYQDLVDERNLNKRCGYPLCGKSPERIR-DPFSMNDTTKKFLLENNPYAYLSHYCSKFHFRCSQFYQVQLSDEALFARTG-----VHLFEDPEQDKHDIDFKVT-----------------------------------------------------------------------------------------------------------LFEELLREKASEEDIKSLISGLKKLGLNPDSGTTEKDDTELEDDLSKWLAQIKIVENDNPSILGDFTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .:: * : : : : * *.* *:** : * ****:* . : : : :. ..:*. .: . :** : ::.*: : *:. .:: * .:*: ", "identical_positions": 20, "similar_positions": 42, "identity": "3.11%" }, { "cls_id": "homologset.agr.SGD:S000000942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4VBD2-1", "uniprot_id": "TAPT1_MOUSE", "id": "Q4VBD2-1", "name": "Transmembrane anterior posterior transformation protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVCDAAAPGEGGGGGADGPERTGRGEAEQPGG-GGHG--PAPQHTETLGFYE-SDRRREKRRG-----RAELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCMRIPRELEKLMFFGIFLCLDAFLYVFTLLPLRVFLALFRLLT--LPCYGLRD-----------RRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKILNSIVLLGKSCQYVKEAKMEEK---------------------------------------------------LFNPPPA-----------------STPGKPSSKSQ--SKGKPSQGLSTEENLS------ASVTSQPGHQKENVIPLLVTSNSDQFLTTPD----GDEKDIT------QENSELKHRSSKKDLLEIDRFTIC----------GNRID--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A632-1", "uniprot_id": "A0A8I6A632_RAT", "id": "A0A8I6A632-1", "name": "", "aln": "MIINMQERCSQGSRATGSAPAGATELEPGPSRRAAKARRVAPAHSGHRTGTRGSGRTESHAEPRRRPPSPTARPGDMEPGAAPRSAEPAARHGDGRKKMAAAVAAATAASHAPLTPMARAGRRTTDGGCPGSGEGRGEAARGPAGGGGRAGGWREVAGTVCGFRNMAGVCDAAAPGEGGGGGADGPERTGRGEAEQPGG-GGHG--PAPQHTETLGFYE-SDRRREKRRG-----RAELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCMRIPRELEKLMFFGIFLCLDAFLYVFTLLPLRVFLALFRLLT--LPCYGLRD-----------RRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKILNSIVLLGKSCQYVKEAKMEEK---------------------------------------------------LFNPPPA-----------------STPAKPSNKSQ--SKCKSSQGLSTEENLS------ASITSQPVHQKENVIPLLVTSNSDQFLTTPD----GDEKDIT------QENSELKHRSSKKDLLEIDRFTIC----------GNRID--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXT6-1", "uniprot_id": "TAPT1_HUMAN", "id": "Q6NXT6-1", "name": "Transmembrane anterior posterior transformation protein 1 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETLGFYE-SDRRRERRRG-----RTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLT--LPCYGLRD-----------RRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEK---------------------------------------------------LSNPPAT-----------------CTPGKPSSKSQ--NKCKPSQGLSTEENLS------ASITKQPIHQKENIIPLLVTSNSDQFLTTPD----GDEKDIT------QDNSELKHRSSKKDLLEIDRFTIC----------GNRID--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIE7-1", "uniprot_id": "TAPT1_DANRE", "id": "A2BIE7-1", "name": "Transmembrane anterior posterior transformation protein 1 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADSVAAGLGDENETENEDKE-REKRLFSGVKKMEKQAAASDVTETLGFYERKAKCKDRKTN-----VSDLSLVRFISAELTRGYFLEHNEAKYTERRERVYTCLRIPKELEKLMIFGYFLCLDVFLYVFTLLPLRVLLALVRLLT--LPCCGLSG-----------SRILQPAQVCDVLKGFIMVLCYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYTLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDVVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVSRRMGFIPLPLALLLIRVVTSSVKIQGSLSIVCVLLFYLGMITLKVLNSIVLLGKSCMYVKEANMEEK---------------------------------------------------LFQNPPS-----------------AAPSRVSSRAHRTKHTREPPGDPAEEGMS------ASVTTQPTQQDECPAPQIPTSESDQFLTTPDE---SEEKSLI------QDDSELKHRAPKKDLLEIDRFTIC----------GNRID--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AGX4-1", "uniprot_id": "A0A8M3AGX4_DANRE", "id": "A0A8M3AGX4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADSLAVGTSDEKDPENEDHKGVKCSWAPER-MSEKTNILTTMTETLGCYENPAVKEEQMEHSDVDEPEDPSLLRFMCAELTRGYFLEHNEAKYTERRERVYTCMRIPRELERLMIFGICLCLDAFLYVFTLLPLRTLLAFLRLLT--IPCCGLGANVCPYCRRSSGSRFLQPAQVCDLLKGLIMVLCYSMMHYVDYAMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKSRKRAHIGVIPHFFMAVFYVFLHSILIMVQASTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNSD-----HLWVLLPDVFMVIMSEVAVDIVKHAFITKFNDITADVYSEYKASLAFELVSSRQQNAYTDYSDSVARRMGFIPLPLAVLLIRVVMSSVKIQGALSSVCLLLFYLGLITLKVLNSIIILGKSCRYVKEAKMEGK---------------------------------------------------LFERPNP-----------------QTPKQTPKKTN-PARSPPPAAEPKMHRPT------ASITKQPTPR-AKLFPSAPTPEPKETVDPPPDPPPPNPEEIIS--ADAQQSTELKHRTSKKDLLEIDRFTIC----------GNRIG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VED0-1", "uniprot_id": "TAPT1_DROME", "id": "Q9VED0-1", "name": "Protein TAPT1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MNATLNSAGGKRQLRFRGDVTGSRVEELHHQQQEEQKQKAPLAQDDVAATPTATPAAGSAQQRLQSGTAETC-------TNTFYDFFKVEMTRGYMLEHDEERYSARRQKIYSFMRIPRDLERFMVYGIMQCADSFLYIHTFLPVRFVMAVWALVS--RTVARIFR------LRSSGQRLLSPAEICDLLKGVIWMTVTLIMLLVDTNRVYHIIKSQSIIKLYIFYNMLEVGDRLLSAFGQDTIDALFWTATEPKNSKREHFGVLTHVLFTLIYVFLHSGLIMFQATCLNVAVNSNNKGLLTIMISNNFVELKGSVFKKFDKNNLFQLTCSDVRERFHLSVLLFIVVIQTMKEFD----------WSIT-----QFCVMLPDCFAVLFTEILIDWVKHAFITRFNELPESIYREYTTSLAYDMTQTRQKHAFSDHSDLVARRMGFIPFPLAVVLIKAIYTAVSFENLAAWLLFLLAYLFAMGLRICLTICALGKACKLMKEHQTERNSSTPSSMTNVPVIGAAAPVSAAATGGQNHNNNNNNNNNSISIGSKPAQVTTLLTPPSAGHLDVSKNFSRTSIASTSTPKKAVSEQELDVTNSLELGATALFSNSDVDLDDVCLNEQVTNTNTSSAVQEVYQEQDLVRSQPDLMLLNNSGDGVTSAKAKKATQRLPKRTHKRSESEPGMPSMVEKGGAAGIAGGNQTTQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40085-1", "uniprot_id": "TAPT1_YEAST", "id": "P40085-1", "name": "Endoplasmic reticulum membrane protein 65", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQHKDTAVAKDTAKKRLLRRNSAPSAIHIISRLDKKWSFLWNTIDRHNIVEE---------------QDESSAAKSEEEHEDDY--ELEQLLNMIRIPMFLEKFMLFALLTSLDCFLYYFTVLPIRLIKGYVKQFKSYRQHYRLQQR-SGHKNKIPFRYRITSREYKERCMIFIIVISSILLSKLDTSKLYHRIKRQSTMKLYMLFSVLEMADKMLASLGQSLLTVMLS----RKNSERILLHKCLLVSMSLTYVTIHGYVLVYQAISLNIAVNSYSNALLTLLLSMQFAEIKSSVLKKFDKEGFFQITIADVVERFKLTLLLSITGLRNLQSWSSSLSNTSINFWSPRSTLSIVINILCGPMVSVVGSEVLVDWAKHAYITKFNRIRPQIYDKFYYIIYKDYSTRTHK---------LEDRLG-LPLPAFVVLFIVMVRPTLFKSSEPSYLPSLFRILFMGASVFL-LALLAKFTLDLILIKWSKR----------------------------------------------------IEQRFR-----------------DQAFNTVVTEEEYVPGLLSGGMGKVDVST-------RIALHSDYNKENRIETESVSPMRKRKTTLTAECTPPSLNDIR---------RQKDSKNPRSLENVARYKMVS----------KRIW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * : . *..* * . ::: . :*** **::*.:. . * *** .*.**:* . . .. : : . : : .* : :: :* :** *: ** :***:::.:**:.*::::::**. : .: *. :* : . ::: ** :*. ::: ** **:*.** .:.***:::* :*.*:*.**:***:*:.:**:: :*: *** ** *. ::.::.:. *. : :: *: :*: :* .***:**:** : .:* :: : : :: : *:* :*:* ::*: .: . .:. . * : : : : *.* : : . . . . . . : : : . . . :. : .: :: ", "identical_positions": 87, "similar_positions": 158, "identity": "10.07%" }, { "cls_id": "homologset.agr.SGD:S000000943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A414-1", "uniprot_id": "D4A414_RAT", "id": "D4A414-1", "name": "", "aln": "-MQRLFLPPLKALMGSRNVGLLVPKAASRAQCGGGSYGGRRPLRPGQYGTITEVALQ----SGKGTVSLPSRAAE---------RAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLE-EKP-ESYDIPRVSQYRLAAHLGSALILYCGSLWTSLSLLLPQHKIP-ETRQLLWLRRFAGGTAG-----------LVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSP-----------ILKNVFENPTMVQFDHRLLGVTSVT--AITMLYFLSRRIPLPRRTKMAAVTLLALAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELR-----------RVPK---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ03-1", "uniprot_id": "COX15_MOUSE", "id": "Q8BJ03-1", "name": "Heme A synthase COX15", "aln": "-MQRLLLPSLRALTGSRNVGLLVPRVASRTQCG-SSCGSQRPLRPGQYSTITEVALQ----SGKGTVSLPSRAAE---------RAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLE-EKP-ESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLP-ETRQLLWLRRFAGGTAG-----------LVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSP-----------VLKNVFENPTMVQFDHRLLGVTSVT--AITVLYFLSRRIPLPRRTKMAAVTLLALAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELR-----------RVPK---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KZN9-1", "uniprot_id": "COX15_HUMAN", "id": "Q7KZN9-1", "name": "Heme A synthase COX15", "aln": "-MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCD----CIRRPLRPGQYSTISEVALQ----SGRGTVSLPSKAAE---------RVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGMKGRVLALCGLVCFQGLLGWYMVKSGLE-EKS-DSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPPHKLP-ETHQLLQLRRFAHGTAG-----------LVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSP-----------ILRNVFENPTMVQFDHRILGITSVT--AITVLYFLSRRIPLPRRTKMAAVTLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELR-----------RVPK---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1F5-1", "uniprot_id": "Q9W1F5_DROME", "id": "Q9W1F5-1", "name": "Cytochrome c oxidase assembly protein COX15 homolog", "aln": "-MLRLLQ------KRTNLIKLVVP-------------------GPRLHQTIAQTAIK----EIPVIKPISTPKSD---------KTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWKLTGERMPRT-QEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSVLLLGTLIGLQGLMGWYMVKSGLE-DRFQDPNDVPRVSQYRLASHLAAAFVLYSLSLSKAMSLLIPTNTFVIQAKKAFNIKGLTHLTKA-----------MVLLTAISGAFVAGLDAGLVYNSFPKMGDKWIPDDMWTFAP-----------IQKNITENPTTVQFNHRILGISTVT--LTTALWLVTRRMQLPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFALWLSHEVRL--------LKYLPK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40086-1", "uniprot_id": "COX15_YEAST", "id": "P40086-1", "name": "Heme A synthase COX15", "aln": "MLFRNIEVGRQAAKLLTRTSSRLAWQSIGASRN-ISTIRQQIRKTQLYNFKKTVSIRPFSLSSPVFKPHVASESNPIESRLKTSKNVAYWLIGTSGLVFGIVVLGGLTRLTESGLSITEWKPVTGTLPPMNQKEWEEEFIKYKESPEFKLLNSHIDLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVSKKTSGHVNKRLFGLAGLLGLQGFVGWWMVKSGLDQEQLDARKSKPTVSQYRLTTHLGTAFFLYMGMLWTGLEILRECKWIKNPVQAISLFKKLDNPAIGPMRKISLALLAVSFLTAMSGGMVAGLDAGWVYNTWPKMGERWFPSSRELMDENFCRREDKKDLWWRNLLENPVTVQLVHRTCAYVAFTSVLAAHMYAIKKKAVIPRNAMTSLHVMMGVVTLQATLGILTILYLVPISLASIHQAGALALLTSSLVFASQLRKPRAPMRNVIITLPHSSKVTSGKILSEASKLASKPL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . . : .::: . . : :: : *. *:: ** * * ***:*********:. *: * *:** ** *:: **:*: * .: : *****: **: **:*** :* ::***.** . : :: * *: :**::**:******: :: . * ******::**.:*:.** * ..:.:* : : .: :: : : . : :***:**.:******* ***::****: *:*.. : :*: ***. **: ** . :.* : :: :.:: :*:.: : .::.:. *. **: *:* ** .**: **:*:* **: :* : ::* :*: ", "identical_positions": 124, "similar_positions": 121, "identity": "25.46%" }, { "cls_id": "homologset.agr.SGD:S000000945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAF3-1", "uniprot_id": "DDI1_MOUSE", "id": "Q9DAF3-1", "name": "Protein DDI1 homolog 1", "aln": "MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDD-HCSLGSYGLKDGDMVVLLQKDNVGLRTPGRTPNHPRADFTGSGSAVPGTSSSRHPHQHQHHYHHHQRIPSTQQAHGLASGENMTFAQELDS-PALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLMEQQRERTLREQEMFRLYSTNPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWGGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSG------TVQEESSDREVGGTIKHPVKGPGRKKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0JPP7-1", "uniprot_id": "DDI1_RAT", "id": "A0JPP7-1", "name": "Protein DDI1 homolog 1", "aln": "MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDD-HCSLGSYGLKDGDMVVLLQKDNVGPRPPGRAPNHPRTDFTGSGSAVPGTSSSRHPHPHQHHHHQHQRIPSTQQAHGLASGENMAFAQDLNS-PALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLVEQQRERAMREQEMFRLYSADPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSG------AVQEDSSDKEVAGSIKHPVKGPGRKKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WTU0-1", "uniprot_id": "DDI1_HUMAN", "id": "Q8WTU0-1", "name": "Protein DDI1 homolog 1", "aln": "MLITVYCVRRDLSEVTFSLQVSPDFELRNFKVLCEAESRVPVEEIQIIHMERLLIED-HCSLGSYGLKDGDIVVLLQKDNVGPRAPGRAPNQPRVDFSG--IAVPGTSSSRPQHPGQ----QQQRTPAAQRSQGLASGEKVAGLQGLGS-PALIRSMLLSNPHDLSLLKERNPPLAEALLSGSLETFSQVLMEQQREKALREQERLRLYTADPLDREAQAKIEEEIRQQNIEENMNIAIEEAPESFGQVTMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGVAKGVGTQRIIGRVHLAQIQIEGDFLQCSFSILEDQPMDMLLGLDMLRRHQCSIDLKKNVLVIGTTGTQTYFLPEGELPLCSRMVSG--------QDESSDKEIT----HSVMDSGRKEH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ADY9-1", "uniprot_id": "DDI2_MOUSE", "id": "A2ADY9-1", "name": "Protein DDI1 homolog 2", "aln": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDN-HRSLASYGLKDGDVVILRQKENADPRPAVQFSNLPRIDFSS--IAVPGTSNPQQRQLPR-----TQAQHSSPGE--MAS-----SPQGLDN-PALLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVAMLYINCRVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYG-TGREDIRPEEIADQELAEAIQKSAEDAERQKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y0Y2-1", "uniprot_id": "A0A8I5Y0Y2_RAT", "id": "A0A8I5Y0Y2-1", "name": "", "aln": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDN-HRSLASYGLKDGDVVILRQKENADPRPSVQFSNLPRIDFSS--IAVPGTSNPQQRQLPR-----TQAQLLSPGE--RTS-----TPQGLDS-PALLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVAMLYINCRVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYG-TGREDIRPEEIADQELAEAIQKSAEDAEKSSKESTSLGTPSLLTSEGLNHPAPSGHSPEVGSPTSLARSVSASVCAIKPSDPNSIGSPAVEATKASAEFQTNSKKTDPPLQVLPDLASSAERSLAMPLHNSSDEAFVTGNLEKSAEKRTQGLRVYLHTRQDASLSLTTTGTHEPQIFVEEKSWHPENQNSSQVNGLQQHRETERVQREPGAQSVPGDRECLCHTEDLELQEEAVGWEAVMKGSGALLSTAHLLSAEEGLPAPGRCSCSCSEALMEVDTAEQSPVASCNSTGRPVITSPGVSHVTSEHPSMEVETSQCNLSCDRVEHSILTRDLQLPDNVEMSTMDNKDDRSSSPLSGHGQPSLESAEEFCSSVTVALKELHELLVISCKPASEDSPEDITCQSEIAAESQASISDLTGRSTQSEHLTPSDQHPQVSCPQATSESEKTEILGAAPHAAGEDDTSTGFGGLGDGLSPGQEGLPRSTESVRKSCSVAITSAKLSEQLPCTSGVESSLELAAGEEGAHSQPSEHVQNPGPDRPETSTVCPGAVLPFGGLDQPTTQSLSTPSTLPPFVFPAADVDRILGAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TDH0-1", "uniprot_id": "DDI2_HUMAN", "id": "Q5TDH0-1", "name": "Protein DDI1 homolog 2", "aln": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDN-HRSLASYGLKDGDVVILRQKENADPRPPVQFPNLPRIDFSS--IAVPGTSSPRQRQPPG-----TQQSHSSPGE--ITS-----SPQGLDN-PALLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYG-AGREDVRPEEIADQELAEALQKSAEDAERQKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TH22-1", "uniprot_id": "DDI2_DANRE", "id": "Q6TH22-1", "name": "Protein DDI1 homolog 2", "aln": "MLLTVFCAPRDRSETTFALDVSPELELRDFLALCELESGIPAGEIQIIYAEQPLQDP-TRALGNYGLKDGDVLVLRQAERLRAPPQPTVPGLPRIDFSS--IAVPGTSSGQNRNRPQQAQRPSTTQPPPPQA--TTSPGSGVSPQGLDN-PALLRDMLLANPHELSLLKERNPPLAEALLSGDLERFTKVLMEQQQDRARRDQERIKLLTADPFDLDAQAKIEEEIRQHNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSFSILEDQPMDMLLGLDMLKRHQCSIDLKKNVLLIGTTGTETRFLPEAELPECARLAYGPEGREEPRPDEIADRELAEAIQRSVQDSGKMHDM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXF9-1", "uniprot_id": "Q9VXF9_DROME", "id": "Q9VXF9-1", "name": "", "aln": "MKITVTTS----DDKVFCLDVAQDLELENLKALCAMEIGAEVSQIAVIFNGRELSSD-KQTLQQCGVGDGDFIMLERRRSAN-RPVGGNPAISTLDFSN--IAVPGTSSGGSPPSRR---VQQQGVQQPQFNNLTDIPTTDEFNVNFDDDPETVRQMFLSSPETLSLLRQYNPSLAEAIDSGDKEKFARLLREHITERKRRNEHRMRMLNADPFDEETQRLIAEEIKQKNIQDNMAAAIEYNPEIFGTVTMLYINCKVNGIPVKAFVDSGAQTTIMSKDCAERCHVNRLIDTRWNGVAKGVGTQPILGRIHMVQLQIENDHLTSSFTVLGQQPMDMLLGLDMLKRHQCLIDLQRNLLIIGTTGTTTPFLPESELPVSARLTGN-------SEDSMEQEAISNAIEQSKRESGGAGGGPNTISPQERFTEQDVTDLMALGYPRSDVLTVLRLCGGNKQAARSVLLHRNDAASGSELS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40087-1", "uniprot_id": "DDI1_YEAST", "id": "P40087-1", "name": "DNA damage-inducible protein 1", "aln": "--MDLTISNELTGEIYGPIEVSEDMALTDLIALLQADCGFDKTKHDLYYNMDILDSNRTQSLKELGLKTDDLLLIRGKISNSIQTDAATLS-----------DEAFIEQFRQELLNN---------------------------QMLRSQLILQIPGLNDLVNDPLLFRERLGPLILQRRYGGYNTAMNPFGIPQDEYTR--------LMANPDDPDNKKRIAELLDQQAIDEQLRNAIEYTPEMFTQVPMLYINIEINNYPVKAFVDTGAQTTIMSTRLAKKTGLSRMIDKRFIGEARGVGTGKIIGRIHQAQVKIETQYIPCSFTVLDTD-IDVLIGLDMLKRHLACVDLKENVLRIAEV--ETSFLSEAEIPKSFQEGLPAPTSVTTSSDKPLTPTKTSSTLPPQPGAVPALAPRTGMGPTPTGRSTAGATTATGRTFPEQTIKQLMDLGFPRDAVVKALKQTNGNAEFAASLLFQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::* :: * :: .* : : : . * . :* . *: .*.::: . . .. : . : . *::: .* *. : . : : ::* * : : * * : *: *:::: *:* ** * * ***** .:*. *:*****:*** **** *:: : *::* *: * *:**** *:**:* .*::** :.: .**::* : :*:*:*****:** . :**:.*:* *. . * **.*.*:* . : :. . . ", "identical_positions": 81, "similar_positions": 95, "identity": "8.08%" }, { "cls_id": "homologset.agr.SGD:S000000946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2B997-1", "uniprot_id": "A0A8M2B997_DANRE", "id": "A0A8M2B997-1", "name": "ubiquitinyl hydrolase 1", "aln": "---MASSSTGSSESGRRRGQRGPDDTVSTSKKKQKDRANQESKEAKRVATSTETKKDLFLDWKQNAYEVIVRLNCGGAGVLRVEDIEYDFSNSACHIRLPDGREWSCHLHEEIEASCSKLNYKEKSNVLQLVMHKKIPLNTWPAYAKKSEPVDILQKNGSNNYQSSTGRSEKSSEAIEKTPPVSSAEQKRGKPDRGLKRGMKGKQVHVTESTGEKTPEIKSSDKADSINEPSAKRTTRPSKNTKEPPLAPCLGNESKSKATVNGKTHTSEVNSGASSSSNAKDNRAQMQGKPQGCQALQKEKGIDRKPKSNAQVGSGESKSVSVCEPQVPQKEHSSPVKTCTDKIASDEPENRKEETKPQAEGHIPKMLPSHDLGSGEPASTDFKSEESPQKSQTEEKRDKSKEEPQGASQEEDTEGPEPMVDLKFVKN------------------------------------DSYEKGTDLMVVNVYMKEICRQTSRVLFREQDFTLIFQTSDPNFLR---------------------------------------------LHSDCGPNTVFKWQVKLRNLIQPDQSNYAFTPSRIDITLKKRHSQRWGGLEAPATQGA---------------------------------------------------------------------------------------------------------VGGAKVAVASSPSTLEKSQPGSSQHALPAKEEPRVGEEKPKPPRAPEDSGLDAVSPRSVSEHVSLKQEPAVATPKPTCMVQPMTHTPPVGN-ERSEEV----------------------------------------------EEKKVCHPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRGFESEINCNNPLGTGGRLAIGFAVLLRALWKGTHHAF--------QPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRQDEVVAE----------------EAWQRHKMRNDSFIVDLFQGQYKSKLVCPMCSKVSITFDPFLYLPVPLPQKQKVLTVFYFAKEPHKKPVKFLVSVSKESSSTAEVLESISRSVRIKPENLRLTEVVKGRFHRIFLPSQSLDTVSSSDLLFCFEMLSKDLIKERVVLLKVQQRPQIPSIPITKCAGCLKPPASDDEKLKRCTRCYRVGYCNQTCQKNHWPSHKTMCRSNVENIGQPFLISVPESRLSYTRLTQLLEGYSRYSVNVFQPPFQSGRTSPES-SLSRVDLTSMASSVPECQEKDLPSAGDAENPAEQDESVTASQTESAADGGDTLSTHTTDSGCCELASSSHDSLLEKETSCEKAVKPEAVVTGYQQPSESASGGASQFYITILDSSQKEDKKLEEKGDAVLELPDECTLELVWKNNERQKEYVLVRSKDLEFDEDPGSATETSRAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCQQHREASKQLLLWRLPNVLIIQLKRFSFRSF--IWRDKINDMVDFPVR---NLDLSKFCIGHKGDI--QQPPIYDLYAVINHYGGMIGGHYTAYARLPSDKNSQLSDVGWRLFDDSTVT-TVEESQVVTRYAYVLFYRRRNSPVERPSHLLG-PLGAESSAATGGAASQASLIWQELEEDEEGQREASFRSLFRPGLRGRRARMRPEQEEEEEGRGGLSHRRRDDNSDYSDGERMRYFILGTVAAILALLFNLIYPLLYWSNWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O94966-1", "uniprot_id": "UBP19_HUMAN", "id": "O94966-1", "name": "Ubiquitin carboxyl-terminal hydrolase 19", "aln": "------MSGGASATGPRRGPPGLEDTTS--KKKQKDRANQESKDGD---PRKETGS------RYVAQAGLEPLASG------------DPSASASHAAGITG---SRHRTRLFFPSSS----------------------------------------GS----ASTPQEEQTKEGACEDPHDLLATP---TPELLLDWRQSAEEVIVKLRVGVGPLQLEDVDAAFTDTDCVVR--------------------------------FAGGQQWGGVFYAEIKSSCAKVQTRKGSLLHLTLPKKVPMLTWPSLLVEADEQLCIP-------------PLNSQTCLLGSEE------NLAPLAG---EKAVP----PGNDPVSPAMVRSRNPGKDDCAK-----EEMAVAADAATLVDEPESMVNLAFVKN------------------------------------DSYEKGPDSVVVHVYVKEICRDTSRVLFREQDFTLIFQTRDGNFLR---------------------------------------------LHPGCGPHTTFRWQVKLRNLIEPEQCTFCFTASRIDICLRKRQSQRWGGLEAPAAR-----------------------------------------------------------------------------------------------------------VGGAKVAVPTGPTPLDSTPPGGAPHPLTGQEEARAVE-KDKSKARSEDTGLDSVATRTPMEHVTPKPETHLASPKPTCMVPPMPHSPVSGDSVEEEEE----------------------------------------------EEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAF--------QPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAE----------------EAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPVFYFAREPHSKPIKFLVSVSKENSTASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLPSHSLDTVSPSDTLLCFELLSSELAKERVVVLEVQQRPQVPSVPISKCAACQRKQQSEDEKLKRCTRCYRVGYCNQLCQKTHWPDHKGLCRP--ENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTGSLEAGDSERDPIQPPELQLVTPMAEGDTGLPRVWAAPDRGPVP---STSGISSEMLASGPIEVGSLPAGERVSRPEAAVPGYQHPSEAMNAHTPQFFIYKIDSSNRE-QRLEDKGDTPLELGDDCSLALVWRNNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSF--IWRDKINDLVEFPVR---NLDLSKFCIGQK--E--EQLPSYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVT-TVDESQVVTRYAYVLFYRRRNSPVERPPRAGHSEHHPDLGPAAEAAASQASRIWQELEAEEEPVPEGSG----PLGPWGPQDWVGPLP------RG----------PTTPDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZL6-1", "uniprot_id": "UBP21_MOUSE", "id": "Q9QZL6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNVQPRVG-----------------------------------------AKIPFPPRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKL--------------------------------------------------ELGRGRTSGSRPRGPLRADHGVPLPGSPPPAVALPLPSRTNLARSKSVSSGD---------------------------------------------------------------------------------------------------------------------LRPMGIALGGHRGAGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPTSHGSFHMISARPSEPFYSDDKMAHHT----------------------------------------------------LLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFR-QEVPGG--GRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRG--SIKKSS-VGVDFPLQ---RLSLGDFASDKA------GSPVYQLYALCNHSGSVHYGHYTALCRCQTG---------WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPLRCL---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GUX4-1", "uniprot_id": "UBP21_RAT", "id": "B2GUX4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNVQPRVG-----------------------------------------AKIPFPPRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKL--------------------------------------------------DLGRGRTSGSRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLTRSKSVSSGD---------------------------------------------------------------------------------------------------------------------LRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPPSHGSFHMISARPSEPFYSDDKMAHHT----------------------------------------------------LLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFR-QEVPGG--GRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGG-ALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRG--SIKKSS-VGVDFPLQ---RLSLGDFASDKV------GSPVYQLYALCNHSGSVHYGHYTALCRCQTG---------WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPPRCL---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UK80-1", "uniprot_id": "UBP21_HUMAN", "id": "Q9UK80-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNIQPRVG-----------------------------------------SKLPFAPRARSKERRNPASGPNPMLRPLPPRPGLPDERLKKL--------------------------------------------------ELGRGRTSGPRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLARSKSVSSGD---------------------------------------------------------------------------------------------------------------------LRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLFSIRTEPPASHGSFHMISARSSEPFYSDDKMAHHT----------------------------------------------------LLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFR-QEVPGG--GRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGG-ALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG--SIKKSS-VGVDFPLQ---RLSLGDFASDKA------GSPVYQLYALCNHSGSVHYGHYTALCRCQTG---------WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPPRCL---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8Z0-1", "uniprot_id": "A0A8M2B8Z0_DANRE", "id": "A0A8M2B8Z0-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAESTSMDN-----------------------------------------------------------------------------------------------------------------SCQALYRTLVTQNG-----------------------------------------------------------------------------------------------------------------------------------------------LQPENVDISQSVLYTSIMG--------------------LLLVTDKERE----------------------------------------------------------------LQLGNGQVGLRNVGNTCFLNAIVQCLSHTRSLRDYCLMRAYV-QDKHSN---QEPVLMDEFSKVLAGLWECDAGETT------VNPGKFYRVFKESVPYFSGYSQQDAQEFLRFLLDRLHTEINRRPSKRPAVIERKEPAYTRFRIS------------EEAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCSHYSNTFDVFCDLSLPIPKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTIQRFPRVLVIHLNRFAMSRF--SISKST-VPVSFPLT---ALDLGLFGPVDC------GPVLYDLYAVCNHSGTVNMGHYTAACREEEG---------WCFYNDSCVD-AISEEKLQSNQAYVLFYELKSCNISRK---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ27-1", "uniprot_id": "UBP2_DROME", "id": "Q8IQ27-1", "name": "Ubiquitin carboxyl-terminal hydrolase Usp2", "aln": "------------------MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEV-------------------------------PSPGGSAGSKVGATNPVRAANQRFFLVSS-------------------------------------------------YKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLF---------------------------------------NGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPL--------------NNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQ------------------------------------QQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSS--------------------------------------------------------------------------LTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLS-----TKDQQILHEFAKLIQEMWT-ANVHT-------VTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALN--SGVKGETLNIDDNLSDNKKAD----------------LTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SS-RCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSET----RWSKLS-NIVEFPTSDS-ELNMGSYGANSN------SNVHYSLYAISNHMGSTAGGHYVALCKHPVSRK-------WHEFNDNIVSDALSENHLVSSSAYILFYERT----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3AST8-1", "uniprot_id": "A0A8M3AST8_DANRE", "id": "A0A8M3AST8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPVYSSPKYATG------STLLSPYSSYDPCDPTLAYIVRG--------------------------------------------QPQLSRYAPSTSRYLSP-SPCLARGVLFFPQEPER---------------------------------------------------------------------GRAALHSEPHVG------------RYSESYSRLQVKG------------------------------------------------------------------------------------------------------------------------QLPRINRPRGRSPSRNGYTCMSPLSRQRRSVSQSDLMRELATLEICDQGAVERTVYAVKESAIRGRTDYSGPLYWTSENS---------------------------------------------------------KNAQGLVGLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRTDLNNNC--RAKAALMDEFAKLTQTIWTSASNEA-------ISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVKSRAPVEDLDHLSEDEKGK----------------RMWNKYLESEDSKVVDLFVGQLKSSLTCSECGFCSTVFDPFWDLSLPIAK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSGEVSLNDCLRLFTKEDVLDGNERPTCHRCKTRRKCTKKFTIQKFPKILVLHLKRFSECRV--RTSKLS-TFVNFPLK---ELDLREFASDNS------VNAVYNLYAVSNHTGTSLGGHYTAYCRSPCTGE-------WYTYNDSRVS-PMSSSQVCSSDAYVLFYECATSSRM-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZN39-1", "uniprot_id": "D3ZN39_RAT", "id": "D3ZN39-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-TSTKNYIHSAQKIFKAAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPA-NIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKIQRVNGEKSEGGAAAERGAVTAKELYTMMMDKNTSLIIMDARKIQDYQHSCILG--SLSVPEEAISPGVTANWIEAKLSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKAVLHHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRPEEVSVSLDFTYPSLEEPVPSKLPAQMPPPPLEANEKAQLVTDQDGKPRPLVQSALAGPSVAPKAEASPIIQPVPATKNVPQVDRTKKPAVKLPEDHRMKSESTD------QSGRVLSDRSTKPVFTSPATMLTDEEKARIHEETALLMEKNRQEKELWERQQKEQKEKLRREEQERKAGKTQDAEE-----------------------------------------RDFTENQHKAKDGQEKRDSKQTKAEDREPPADGAQDATGTQRQSKSEHDASDAKVSVE--GKRCPMSEVQKRPADVSSASSMSGELSAG-----------------------------KAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSVPPSTPPTHKVKPQIPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPTVNRENKPPCYPKAEISRLSASQIRNLNPVFGG----------------------------------------------------SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYI--------SPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAE----------------HAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFPLEN---LDLSQYVIGPKS-----SLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQR-------WFKFDDHEVS-DISVSSVRSSAAYILFYTSLGPRVTEAAT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U87-1", "uniprot_id": "UBP8_MOUSE", "id": "Q80U87-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-TSTKNYIHSAQKIFKTAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPA-NIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKTQRINGEKSEGAAAAERGAITAKELYTMMMDKNTSLIIMDARKIQDYQHSCILD--SLSVPEEAISPGVTASWIEANLSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKTVLRHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRAEEVSVSLDFTYPSLEEPVPSKLPTQMPPPPIETNEKALLVTDQDEKLRLSTQPALAGPGAAPRAEASPIIQPAPATKSVPQVDRTKKPSVKLPEDHRIKSENTD------QSGRVLSDRSTKPVFPSPTTMLTDEEKARIHQETALLMEKNKQEKELWDKQQKEQKEKLRREEQERKAGKTQDADE-----------------------------------------RDSTENQHKAKDGQEKKDSKQTKTEDRELSADGAQEATGTQRQSKSEHEASDAKVPVE--GKRCPTSEAQKRPADVSPAS-VSGELNAG-----------------------------KAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKVKPQVPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPMVNRENKPPCYPKAEISRLSASQIRNLNPVFGG----------------------------------------------------SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYI--------SPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNEHLDDLQAAE----------------HAWQKHKQLNESIIVALFQGQFKSTVQCLTCRRRSRTFEAFMYLSLPLASTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFPLEN---LDLSQYVIGPKN-----SLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQR-------WFKFDDHEVS-DISVSSVRSSAAYILFYTSLGPRITDVAT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40818-1", "uniprot_id": "UBP8_HUMAN", "id": "P40818-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MPAVASVPKELYLSSSLKDLNKKTEVKPEK-ISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPG-NIKKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEKGAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILH--SLSVPEEAISPGVTASWIEAHLPDDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEE-----------------------------------------NEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGG----------------------------------------------------SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYI--------SPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAE----------------HAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG---RWKQKLQTSVDFPLEN---LDLSQYVIGPKN-----NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQR-------WFKFDDHEVS-DISVSSVKSSAAYILFYTSLGPRVTDVAT-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDD8-1", "uniprot_id": "Q9VDD8_DROME", "id": "Q9VDD8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----MAKLKKLHMSSNLDDLEKMSIIPDLRSKGMKILLNTARKLYMTAEEYRLDGDEELAYITYMKYFNMLTAIHKKSDYPSHKTTVRQMLGDTESNRRIMDTLEEIINSLRHRYAQQHQAPEPIAPDLVSNGRAG--------------------------------VDSPITQPTQYARLGLITCQDLYRRMQEK--SVLVMDCRPSADYEASHLTYYCAFNVPEELITPGMSAGRLQARLSSSAKASWASRSVKDSVVLMDWNTKDAQPATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAP-QQNNNDIETIDDIEYPSIHDIT-----------------MKEDISAKDFRPRPDFN--RANKPAATRVNEQGISRPSPPAKPIAEIMRDQAEFLQRAEQNDEQLEKAS------------------------------KMWKRQAAEGDGLNATEDQELHFRILQLESKAQDYIVENNRLREELSRIQEL-----------------------------------------HNVTQQLS-----------------QKEVEATRNIESKIRERQRLDEQHELERQERER----------------------------------------------------------------------------------------LLAIARETKKHYKSPT----------------PSGPPSPGRNLEDVHVVSDSLESLLQLTGDPDPTIAPN------KAEIPTFDRAMKP----QPRNVERTSQRVRDFSPVIGQN---------------------------------------------------VGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKT--NGQVIEEVAALIKELWNGQYKCV--------ASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQR--------EMISASE----------------KAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VCQLNQCMDMYFSGERIHGWN---CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLEN---LDMNPYIARAESRA--VTPKTYQLYAVSNHYGTMEGGHYTAFCKSANYGK-------WFKFDDQVVS-ALDSSNVVSSAAYILFYTWLPPMQVPL---------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6P8X6-1", "uniprot_id": "UBP50_MOUSE", "id": "Q6P8X6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 50", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCFIDMASHRPVPADDFGAYYNLAECAD-----------------------------------YDSLPESKT---QPHFQG--------------------------------------------------------VTGLRNLGNTCYMNAILQCLCSVSPLVEYFLSGKYITALKK-----DCSEVTTAFAYLMTDMWLGDSDCV--------SPEIFLSAVGSLYPAFLKKTQQDAQEFLIYVLNELHEALKK--HCRRRV-------NEKRTGQ----------------SCCRKVPAQETSIITRLFEGQLSYSITCLKCESCTHKNEVFTILSLPIPSDY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ECSLQDCLQCFFQQDTLTWSNQIYCSFCEIKQEAAVRTTISKVPKIIVFHFKRFDIQG---TVKRKLRTDIHYPLTN---LDLTPYICPVFR-----KHPMYNLCAVVNHFGDLDGGHYTAFCKNSVTQA-------WYSFDDTRVS-EIPDTSVQTATAYLLFYSCQPFSIPAQKRKSQDSTPDHCKQAIRKWP-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LYZ4-1", "uniprot_id": "F1LYZ4_RAT", "id": "F1LYZ4-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASHRPFPADDFGAYYILAECAD-----------------------------------YDSLPESET---QPHFQG--------------------------------------------------------VTGLRNLGNTCYMNAILQCLCSTSPLVEYFLSGKYITALQK-----DCSEVTTAFAYLMTDMWLGDSDCV--------SPEIFLSAVGSLYPAFLKKTQQDAQEFLIYVLNELHEALKK--HCRGRA-------SEKRTAQ----------------NCCRKVPAHETSIITRLFEGQLSYSITCLKCETCTYKNEVFTILSLPIPSEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ECSLQDCLQCFFQQDTLTWNNQIHCSFCEIKQETAVRTTISKAPKIIVLHLKRFDIQG---AVKKKLRTDIHYPLTN---LDLTPYICPVFR-----KHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA-------WYSFDDTRVS-EIPDTSVQTATAYLLFYSCQPFSIPTQKRKSWDSTPDYGKPAVRKWP-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70EL3-1", "uniprot_id": "UBP50_HUMAN", "id": "Q70EL3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 50", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSQPSLPADDFDIYHVLAECTDY----------------------------------YDTLPVKEADGNQPHFQG--------------------------------------------------------VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCV--------SPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRS-------YEKGSTQ----------------RCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQG---TTKRKLRTDIHYPLTN---LDLTPYICSIFR-----KYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39944-1", "uniprot_id": "UBP5_YEAST", "id": "P39944-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "------------------------------------------------------------------------------------------MGSEQALSEVVESAKERFGRLR----------------------------------------------------HLVQKFLDDDDVPQECLPLLQECAEIWSSYVDACQDITMQAPKEDANRLSKGFLR----------------------------------------------LNETAFLYYMIVYTLLEDTLPRLKEFSSNKDQNVRNLYGERIQLLHNDPNIERIRNVIENYPKFIQLQTIEPGKLSSMLHFHGDALLLIDVRPRSEFVRAHIKCKNIICIDPASFKDSFTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQ------------------------------------QRQTRILAKILSQNSVIKPLSGTKILILENGFSNWVKLGGAYQSSVSET--------------------------------------------AHLTSSSSTPAFGSPQVPTGLFNQKSLSPNKDKSMPMVSMNTQPLLTTVQRPQLP-----------------------------------------------------------------------------------------------------------------LYYSDLPIIPQPSPNRNSPTVQKFSPHPPTTLSKLNTPSTIQNKANTVERISPDIRAAQAHAYLPPASNVFSPRIPPLPQQNLSSSRQTILNN-----------------------------------------------SQVLDLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMS----------IRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKG-------WYFFDDSLYRPITFSTEFITPSAYVLFYERIF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:** * :*.: *.* * : .. : : . : : *:*.:*: .:: ** :: . * : ** * : * * : : * :.: :. : *: : : : : * * : : : * ::.:::** : . :. * * .: * * ***.: ", "identical_positions": 35, "similar_positions": 55, "identity": "1.99%" }, { "cls_id": "homologset.agr.SGD:S000000948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4Y9-1", "uniprot_id": "LSM5_HUMAN", "id": "Q9Y4Y9-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEF-EITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62322-1", "uniprot_id": "LSM5_MOUSE", "id": "P62322-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEF-EITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBJ0-1", "uniprot_id": "D3ZBJ0_RAT", "id": "D3ZBJ0-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVSILFISVCLFSEITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRT7-1", "uniprot_id": "Q9VRT7_DROME", "id": "Q9VRT7-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MTAVPPPSNISTLMPLELVDKCIGSRIHIIMKNDKEMVGTLLGFDDFVNMLLDDVTEY-ENTPDGRR----ITKLDQILLNGNNITMLVPGGELAE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40089-1", "uniprot_id": "LSM5_YEAST", "id": "P40089-1", "name": "LSM complex subunit LSM5", "aln": "-------MSLPEILPLEVIDKTINQKVLIVLQSNREFEGTLVGFDDFVNVILEDAVEWLIDPEDESRNEKVMQHHGRMLLSGNNIAILVPGGKKTPTEAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::***::** *..:: *:::.::*: ***:******.::: .. : . : * : : .::**.****::*****: . ", "identical_positions": 29, "similar_positions": 37, "identity": "29.0%" }, { "cls_id": "homologset.agr.SGD:S000000950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6SJ95-1", "uniprot_id": "TBPL2_MOUSE", "id": "Q6SJ95-1", "name": "TATA box-binding protein-like 2", "aln": "MVGSLIMEEDIYLDLFLDPYTIQDDFPPAMSQLFSPGVPLDMHSL-PSNPETVFHPHLGGVKKASTDFSSVDLSFLPDELTQENRDQTVTGNKLASEESCRTRDRQSQLQLPDEHGSELNLNSNSSPDPQSCLCFDDAHSNQPSPETPNSNA---------LPVALIASMMPMNPVPGFSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEEESRLAARKYARVVQKLGFPVRFFNFKIQNMVGSCDVKFPIRLEILALTHRQFSSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6H909-1", "uniprot_id": "TBPL2_RAT", "id": "A6H909-1", "name": "TATA box-binding protein-like 2", "aln": "------MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNA---------LPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSS-YEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6SJ96-1", "uniprot_id": "TBPL2_HUMAN", "id": "Q6SJ96-1", "name": "TATA box-binding protein-like 2", "aln": "-----MEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNP-EVKETSGDFSSVDLSFLPDEVTQENKDQPVIS-KHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDS---------LSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HB1-1", "uniprot_id": "Q66HB1_RAT", "id": "Q66HB1-1", "name": "", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPVQNTNSLSILEEQQRQQQQQQQQQQQQQQ---------------------QAVATAAASVQQSTSQQPTQGASGQTPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29037-1", "uniprot_id": "TBP_MOUSE", "id": "P29037-1", "name": "TATA-box-binding protein", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQ-----------------------QAVATAAASVQQSTSQQPTQGASGQTPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20226-1", "uniprot_id": "TBP_HUMAN", "id": "P20226-1", "name": "TATA-box-binding protein", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXL3-1", "uniprot_id": "TBP_DANRE", "id": "Q7SXL3-1", "name": "TATA-box-binding protein", "aln": "--MEQNNSLPPFAQGLASPQGAMTPGLPIFSPMMPYGTGLTPQPVQNSNSLSLLEEQQRQQQQQQAASQQQ---------------------------------------GGMVGGSGQTPQLYHSTQ--AVSTTTALPGNTPLYTTP---------------LTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRGEIYEAFENIYPILKGFRKTS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13393-1", "uniprot_id": "TBP_YEAST", "id": "P13393-1", "name": "TATA-box-binding protein", "aln": "-----MADE--------ERLKEFKEANKIVFDP--------------------NTRQVWENQNRDGT---------------------------KPATTFQSEED----------------------------IKRAAPESEKDT-------------------------------SATSGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSS-YEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P20227-1", "uniprot_id": "TBP_DROME", "id": "P20227-1", "name": "TATA-box-binding protein", "aln": "--MDQMLSPNFSIPSIGTPLHQMEADQQIVANPVYHPPAVSQPDSLMPAPGSSSVQHQQQQQQSDASGGSGLFGHEPSLPLAHKQMQ-----SYQPSASYQQQQQQQQLQSQAPGGGGSTPQSMMQPQTPQSMMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSS-YEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKKQS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q1JPY4-1", "uniprot_id": "TBPL2_DANRE", "id": "Q1JPY4-1", "name": "TATA box-binding protein-like 2", "aln": "----MNMDEEASLESYFDQTIAGSSDYIFEGDLGLQGSTSQLQDSSFLSSLASQEKDLTEDLDLSFLPD-------------------------ELSTQDEPSQVEKESKNEDSGIYTDCPQKEST---QADIDTSNSAQNTSQFNLP---------------MTPMTPMTPMTPVAESSGIIPQLQNIVSTVNLACPLDLKSIALQARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVCFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFRKQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62340-1", "uniprot_id": "TBPL1_MOUSE", "id": "P62340-1", "name": "TATA box-binding protein-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHAS-YEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVK-AVATAVEQIYPFVFESRKEIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62380-1", "uniprot_id": "TBPL1_HUMAN", "id": "P62380-1", "name": "TATA box-binding protein-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHAS-YEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVK-AVATAVEQIYPFVFESRKEIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A122-1", "uniprot_id": "A0A8I6A122_RAT", "id": "A0A8I6A122-1", "name": "TATA box-binding protein-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHAS-YEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVK-AVATAVEQIYPFVFESRKEIL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : *:*.. * *:*:.:**.. *. *: : .. *:*::*:*: ** *::***:: ***.**:::::.:*: ** :**:** . * :**: *::. *:: * *** :. .: .:* *****.*.: *:: : .* ** :*.:.:**.: : : *.: ::*.: :* ", "identical_positions": 57, "similar_positions": 74, "identity": "15.75%" }, { "cls_id": "homologset.agr.SGD:S000000953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52479-1", "uniprot_id": "UBP10_MOUSE", "id": "P52479-1", "name": "Ubiquitin carboxyl-terminal hydrolase 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALHNPQYIFGDFSPDEFNQFFVTPRSSVELPPYSG--------------------TLCSIQAEDELPDGQEHQRIEFGVDEVIEPSEGLPPTPSYSISSTLN----------------------PQAPEFILGCTTSKKIPEAVEKDETYSSID-QYPASALALESNSNAEAETLENDSGAGGLGQRERKKKKKRPPGYYSYLKDGGEDSASPATLVNGHATSVGTSGEAVEDAEFM-DVLPPVMPRTCDSPQNPVDFISGPVPDSPFPRTLGGDARTAGLCEGCHEADFEQPCLPADS----LLRTAGTQPYVGTDTTENFAVAN------------------------GKILESPGE-DTAANGAELHTDEGADLDPAKPESQSPPAESALSASGAIPISQPA--------------------------------------------------------------------------KSWASLFHDSK-----------------------------PSASSPMAYVETKCSPPVPSPLASEKQMEVKEGLVPVSEDPVAIK--------------------------------------------IAELLETVTLIHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRP-CTSTPMIDSFVRLMNEFTNMPVPPKPRQ---------------ALGDKIVRDIRPGAAFEPTYIYRLLTVI-KSSLSEKGRQEDAEEYLGFILNGLHEEMLSLKKLLSPTHEKHSVSNG---------------------------------PRSDLIEDEELEDTGKGSEDEWEQVGPKNKTSITRQADFVQTPITGIFGGHIRSVVYQQSSKES--ATLQLFFTLQLDIQSDKIRTVQDALESLVARESVQGYT-TKTKQEVEVSRRVTLEKLPPVLVLHLKRFVYE--------------KTGGCQKLVKNIDYPVDLEISRELLSPGIKNKNFK--CQRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVKP----PADRTAYLLYYRRVDLL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR59-1", "uniprot_id": "UBP10_RAT", "id": "Q3KR59-1", "name": "Ubiquitin carboxyl-terminal hydrolase 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALHNPQYIFGDFSPDEFNQFFVTPRSSVELPPYSG--------------------TQCGIQAEEELLDGQEHQRIEFGVDEVIEPSDGLQRAPSYSISSTLN----------------------PQAPEFILGCPTSKKTPDDIEKDETYSSID-QYPASALALESSSNAEAETLENDSGAGGLGQRERKKKKKRPPGYYSYLKDGSEEGASPAALVNGHATSVGTNSEGVEDPEFMVDMLPSVMPRTCDSPQNPMDLISDPVPDSPFPRTLGGDARTAGLPEGCRETDFEQPCLPTDN----LLRTAVTQPNAGADTTENLAVAN------------------------GKILESLGEGTAAANGVELHTDESADLDPAKPESQSPPAESALSVSGAISISQPA--------------------------------------------------------------------------KSWASLFHDSK-----------------------------PSSSSPVAYVETKCSPPVPSPLASEKQMEVKEGLVPVSEDPVAIK--------------------------------------------IAELLETVTLVHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRP-CTSTPMIDSFVRLMNEFTNMPVPPKPRQ---------------ALGDKIVRDIRPGAAFEPTYIYRLLTVI-KSSLSEKGRQEDAEEYLGFILNGLHEEMLSLKKLLSPTHEKHSVSNG---------------------------------PGSHLIEDEELEDTGEGSEDEWEQVGPKNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSSKES--ATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYT-TKTKQEVEVSRRVTLEKLPPVLVLHLKRFVYE--------------KTGGCQKLVKNIEYPVDLEISRELLSPGVKNKNFK--CHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVRP----SADRTAYLLYYRRVDLL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14694-1", "uniprot_id": "UBP10_HUMAN", "id": "Q14694-1", "name": "Ubiquitin carboxyl-terminal hydrolase 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALHSPQYIFGDFSPDEFNQFFVTPRSSVELPPYSGT-------------------VLCGTQAVDKLPDGQEYQRIEFGVDEVIEPSDTLPRTPSYSISSTLN----------------------PQAPEFILGCTASKITPDGITKEASYGSIDCQYPGSALALDGSSNVEAEVLENDGVSGGLGQRERKKKKKRPPGYYSYLKDGGDDSISTEALVNGHANSAVPNSVSAEDAEFMGDMPPSVTPRTCNSPQNSTDSVSDIVPDSPFPGALGSDTRTAGQPEGGPGADFGQSCFPAEAGRDTLSRTAGAQPCVGTDTTENLGVAN------------------------GQILESSGE-GTATNGVELHTTESIDLDPTKPESASPPADGTGSASGTLPVSQP---------------------------------------------------------------------------KSWASLFHDSK-----------------------------PSSSSPVAYVETKYSPPAISPLVSEKQVEVKEGLVPVSEDPVAIK--------------------------------------------IAELLENVTLIHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRP-CTSTPMIDSFVRLMNEFTNMPVPPKPRQ---------------ALGDKIVRDIRPGAAFEPTYIYRLLTVN-KSSLSEKGRQEDAEEYLGFILNGLHEEMLNLKKLLSPSNEKLTISNG---------------------------------PKNHSVNEEEQEEQGEGSEDEWEQVGPRNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSSKES--ATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYT-TKTKQEVEISRRVTLEKLPPVLVLHLKRFVYE--------------KTGGCQKLIKNIEYPVDLEISKELLSPGVKNKNFK--CHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVKP----TAERTAYLLYYRRVDLL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0L7-1", "uniprot_id": "Q9W0L7_DROME", "id": "Q9W0L7-1", "name": "ubiquitinyl hydrolase 1", "aln": "MASTSSSASTTAGSSGAAGGGAATPISTPSTPQPSGVSSGPGNNGNNNNNHHNNTLVSPSGNNNLMTPVQAFTPTGQPVYNPPVYMSAHGGHPHAGAHYPAMIPAPMPSNHVYVNNVTANVNLHGWPHGVPAYMPPGGQHHYIGHGDMPQEQGNTVMPHLQPVPINLAPQGGSPNPHGPRMGGGRMRERGRPRGGGPRRNDYHGPRHLQQQQLITLPPQQQLPPPDGANPGLQLQPDQIGQQLAPPEAHMQHLQQYYAAPPTYAYGPYPSPYFTPQHANVQPPPNATAAQQATGTPLFISGPLMYNPAWFNHGGYIYPMMHPAEYQYVPEDAGQPGVDERGAQPDGGMTQIWHQGPMYAEDFEALQQQQQQQQVAVHPNGGAVSVADELNHNSSSLPSSETSSMISPNYPIYDPQMHEMQHQMGVMQIFDDGQMAALQPIHPGAGPLPQYEDELAECGAPPPGPIPVAWTAAMPLPPDAVQPALLPPPPHHILQQTSPLLIEQPAQLVQAQPPQPPTPTPQQQQQQQHQEQTADKSLTQNNNEVVALDEKLANEKQQQIDFHQQQQEQQQQQQQQQQQQQLHPLAQQQQQEEQQQPQQLQPLQTEKPPTKVPNLVVATVAPQLQQPPLQQHQQQQTSPVVVSPKQQQQQSQAAHQNSYHDQHPLPQQQQPQQQQPQPQRKPSQQYNQAQQQQVRRKYSSEYNHHHHQHGSSDTGIQTTKTMSWTNSAQHKKSTQS--VSVTASPNSVNNGPGVGAAGKANYSHTTKTFTNQQHYQQQHYHTQNSYNNNSSGGGSSSNSSSSSSNNQPQVRNYGTMKMPSSPVAWTAPTPERKNSQQAAAAPAAATASAAPVAITTVTTSTASITATPNQFQPETGSSSASPAVAAAQQQQPAAQQHAQAAQTGAAAAPSKSHSNYASSKKHQSYEPVVLSSVVATSSSANPQPQLNLAPPAPPASQNSSDSSQLSWASLFASNKPVAKVAPYEASKIAQQQPSHPVLQLAPPQPAQVAAAAPVAQLSSPPQNLPLPTAHQQSQLPAPVPAPTAPLVTPGALSYSAASAQAVPAPSPASASVKPLKPEPPRPVQQQLDEWTSKYAEYLTRHKTNLASISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLS--EVKTPTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSK-----GKDDFVGSDLQCDMAFEPTEIYKLWNDS-REEHVE-GRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQ--------------------------------------------NGQEPAEPEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQREGEHST--DVIQPFFTLQLNIEK--AASVKEALEILVGRDQLEGVTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDYR--------------SDG-CTKILKKVDFPVELKIDAKILGS---KKTSQ--KQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRYDDSSVKPVSEKHVLQP----HTPRVPYLLYYRRSDTLPPQQQQTQQQNGGGSGGVVGSSSSSSNAGDNK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01477-1", "uniprot_id": "UBP3_YEAST", "id": "Q01477-1", "name": "Ubiquitin carboxyl-terminal hydrolase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNMQDANKEESYSMYPKTSSPPPPTPTNMQIPIYQAPLQMYGYTQAPYLYPTQIPAYSFN------------------MVNQNQPIYHQSGSPHHLPPQNNINGGSTTNNNNINKKKWHSNGITNNNG-------------------SSGNQGANSSGSGMSYNKSHTYHHNYSNNHIPMMASPNSGSNAGMKKQTNSSNGNGSSATSPSYSSYNSSSQYDLYKFDVTKLKNLKENSSNLIQLPLFINTTEAEFAAASVQRYELNMKALNLNSESLENSSVEKSSAHHHTKSHSIPKHNEEVKTETHGEEEDAHDKKPHASKDAHELKKKTEVKKEDAKQDRNEKVIQE-----------------------PQATVLPVVDKKEPEESVEENTSKTSSPSPSPPAAKSWSAIASDAIKSRQASNKTVS-------------------------------------------------------------------------GSMVTKTPISG-----------------------------TTAGVSSTNMAAATIGKSSSPLLSKQPQKKDKKYVPPSTKGIEPLG-----------------------------SIALRMCFDPDFISYVLRNKDVENKIPVHSIIPRGIINRANICFMSSVLQVLLYCKPFIDVINVLSTRNTNSRVGTSSCKLLDACLTMYKQFDKETYEKKFLENADDAEKTTESDAKKSSKSKSFQHCATADAVKPDEFYKTLSTIPKFKDLQWGHQEDAEEFLTHLLDQLHEELISAIDGLTDNEIQNMLQSINDEQLKVFFIRNLSRYGKAEFIKNASPRLKELIEKYGVINDDSTEENGWHEVSGSSKRGKKTKTAAKRTVEIVPSPISKLFGGQFRSVLDIPNNKESQSITLDPFQTIQLDISDAGVNDLETAFKKFSEYELLPFKS--SSGNDVEAKKQTFIDKLPQVLLIQFKRFSFINNVNKDNAMTNYNAYNGRIEKIRKKIKYGHELIIPEESMSSITLKNNTSGIDDRRYKLTGVIYHHGVSSDGGHYTADVYHSEHNKWYRIDDVNITELEDDDVLKGGEEASDSRTAYILMYQKRN----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* : * . . . . : : .: . : .. : . : . . . .. . : .: . . : . . . . : .. .. . .. . . . . : . : :. . . . :: . . . . * . : . . .: : . . : * .: . .: . : : ** : : . ** . : . *: ***: *:.* *::.: **.*: * *: .::. :. . ::: : : .:* . . : . . . *.:* :*: . : . : *:******:* .:*: *::*::. . : : : :. : . :.* : .* .:: :*:: :* *.:** : ..:.: .:: * *:**:*.. :: *:: : : : : .: ::* :: ::*** **::::* * : * *: *::.: :* * : :.. ::. . .* *:* .*:**.* .: *** :**:: . * * ** .:. :.: .*:: *..*:* *:: : ", "identical_positions": 83, "similar_positions": 227, "identity": "5.19%" }, { "cls_id": "homologset.agr.SGD:S000000954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VTD9-1", "uniprot_id": "Q9VTD9_DROME", "id": "Q9VTD9-1", "name": "Aminotransferase class I/classII large domain-containing protein", "aln": "MLKSSQDRKLKHLFDGGDWNVYAP--NILNLGVGAPGPDILTANCDSFRTATDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVN-------CEDLIITTGASHG-LHILLSTMLDFEG-----FVFVDEYTYMIALDSIKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRRFQSK--------------KKEFWGIYYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYG----ETPTHSRLLSYDDRNDAN----FAGHVISNGSFSKILGPGVRLGWLEVP-PRLKPILDGSGFATSGGCFNNYTSGIVGSLFELKLAQKQISESYEAYKERMLATTQVLRDELPDCCKLVSPTGGYFIWVRIPDRLDCREFLKYCMENHKIYFIVGTRFSADGQS---GKQFFRLSIAFYPKSKLVDGARRLCNALKDYIAEQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10356-1", "uniprot_id": "YEY2_YEAST", "id": "P10356-1", "name": "Uncharacterized protein YER152C", "aln": "-----MKYKEINFFKGHPSSRLLPREAVIQATAAILGPETREYDNDPYNRHP---------------LTYGSDEGALWVREQICTFLNDQLFKFENGARSRTRADYLNLNSGASYGMLNILLQTTLPHNGYTRQAFIITPTYFLINNCFTDAGFKGKMTAINEQGHDSIDFESLISALEQHEAEPQPHSTTEMIQGPKLTKKVYRYVMYCIPTFANPSGNTYSLETRRRLIDIARKYDMLIITDDVYDILDYTTPSDELPSPPLRMVHIDRSTAPSGEDSFGNTVSNATFSKLIAPGLRFGYHESINANLARQLSKGGANVSGGTPSQLNSMIVGEMLRSGAAQRCIAHLRSVYSERATVLTSALKKYMPLGTEIMPLKGGYFTWITLPPAYNAMEISTILAKKFNVILADGSNFEVIGDEKNWGQSCFRLSISFLEVDDIDRGIELFGAVCKSHAITNNITM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::*.* . * ::: .. **: : *.:. . : **. .*:: **.:*.*::.: : . * .: * :.:***:* *:***.* * .:* *::. * : : *. . : ..*.:*::.* . :.::. :.: ** : : * ***: **:* :* *. * ::::**:**:*:: ****:**:* * *: . : : **. * *:.:**.:***::.**:*:*: * ..* *. .* .*** .: .* ***.::. **: *:. ..*.** . *..*:. :* :::. .**** *: :* :. *: . ::.:: : *:.*.. *:. *:. *****:* ..: * . : . *.: : ", "identical_positions": 111, "similar_positions": 155, "identity": "23.97%" }, { "cls_id": "homologset.agr.SGD:S000000956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRH1-1", "uniprot_id": "D3ZRH1_RAT", "id": "D3ZRH1-1", "name": "", "aln": "MTVSQNSWPRHVFINNSLRVIMLGTWALVEKPTITGLTSCPFPKWPLPQLQSSVCACARVSSLPGKMAMGSVCRRWQLLRLLQPPRSFHSVAGS----LKPLATKLLAARS-GSGRPHYALLAVLTPRCISTSAALFAEAQVQVPPVVPAASAPAAVPEVASAG----PADVVQ-CATEQSFAELGLGS--YTPVGLIQNLLEYIHVDLGLPWWGAIATCTVLARCLVFPLIVKGQREAAKIHNHMPEMQKFSARIREAKLSGDQAEFYKATIEMTHYQKKHDIKFFRPLILPLTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYVLPLVVTATMWGVLELGAETG-MQSSDLQLMRNVIRVMPLAVLPVTIHFPSAVFMYWLSSNVFSLCQVACLRFPAVRTALKIPQRVVHDPSKLPPREGFLKSFKKGWKNAEIAHRLREREERMQKHLDLAARGPLRQTFTHNPLLQHDPSRSPNTPNSSTNSVKANTKKPWQDTLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGA9-1", "uniprot_id": "OXA1L_MOUSE", "id": "Q8BGA9-1", "name": "Mitochondrial inner membrane protein OXA1L", "aln": "------------------------------------------------------------------MARNLVCGRWQLLRLLRPQRSYHSVAVS----LRPLAAELLAARR-GNGRPPCALLAVFTPRCISTSATLFAEAQVQAPPVIPATSIPAAVPEVASGG----AADVVQ-CATEPSFTELGLGS--YTPVGLIQNLLEYIHVDLGLPWWGAIATCTVLARCLVFPLIVKGQREAAKIHNHMPEMQKFSARIREAKLAGDQAEFYKATIEMTRYQKKHDIKLLRPLILPLTQAPVFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYVLPLVVTATMWCVLELGAETG-VQSNDLQFMRNIIRVMPLVVLPVTIHFPSAVFMYWLSSNVFSLCQVACLRIPAVRTVLKIPQRVVHDPDKLPPREGFLKSFKKGWKNAEIAQQLREREQRMQKHLDLAARGPLRQTFTHNPLLQHDPSHPPKAPNSNNSSIKANAKKPWQDTLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15070-1", "uniprot_id": "OXA1L_HUMAN", "id": "Q15070-1", "name": "Mitochondrial inner membrane protein OXA1L", "aln": "------------------------------------------------------------------MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPAAPCCCRPHYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGE----TADVVQ-TAAEQSFAELGLGS--YTPVGLIQNLLEFMHVDLGLPWWGAIAACTVFARCLIFPLIVTGQREAARIHNHLPEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAETG-VQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAARGPLRQTFTHNPLLQPGKDNPPNIPSSSS---KPKSKYPWHDTLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFT8-1", "uniprot_id": "F1QFT8_DANRE", "id": "F1QFT8-1", "name": "", "aln": "------------------------MAALRGRVVTECLTTCIFRQTSTP----------SVSTLPIVLTRNEWFVQRSHLHTGKGNRGLVRALLGCQNHGQFLLVNAVGIRHNSSQTVETTVQRVSTP-SEPPDAAISAPASIPAPAVDPTPSVTPQITEQVAEAPL-TALDVLQGVGAEASLSELGLCN--STPVGLIQNLLEFMHVSIGLPWWGAIVAGTIVARCAVFPVIVKGQREAAKLNNVMPEMTKLTNRMNEAKQSGNKFEFSKAYTDLMMFQKKKDVNPFRGFLVPLVQAPIFLSFFIALRKMSELPVPSLQTGGLWWFTDLTAADPFYILPIAVTGTMVAILELGAESG-VDNPNLRAMKTVFRIMPFVILPLTINFPTAVFTYWMTSNLFSLAQVAVLRHPAVRQKLRIPERIVHPQSALPENEGFFATVKKGWKNAQLAQQLEERERRIKGHLDIAAKGPLRQTFTHNPLQQSAAPMSTGKPSNPN----QGKKRPWEDTIG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y171-1", "uniprot_id": "Q9Y171_DROME", "id": "Q9Y171-1", "name": "", "aln": "--------------------------MLAHRMQLWRTTN-------------------------AAMAMTSAAGRFTPQASTGSRRDLYLQRITR----GSSLPLAAPEKWSNLGQLRFASGGATAAGVSATKGEEFMQAVPKTELVDLPDIPAAPVPPPADGLN---VMDVMN-AAGEPSFASIGLGG--WSPVGMVQNCLEFLHCTWDIPWWGTIAIGTLAVRTIIFPLVILAQRNSAKMNNNMPQMQMLQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANAPVESMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVIFPFTMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESWDNMKISKEIEERQRLDEIRFAKAGKGPLVKTYKFDPTKVAKPISAEPHMRLKE----PPNKQG------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39952-1", "uniprot_id": "OXA1_YEAST", "id": "P39952-1", "name": "Mitochondrial inner membrane protein OXA1", "aln": "---------------------------------------------------------------MFKLTSRLVTSRFAASSRLATARTIVLPRPHP----------------------SWISFQAKRFNSTGPNANDVSEIQTQLPSIDELTSSAPSLSASTSDLIANTTQTVGELSSHIGYLNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAATTILIRCLMFPLYVKSSDTVARNSHIKPELDALNNKLMSTT---DLQQGQLVAMQRKKLLSSHGIKN-RWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETG--AQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPR----TPIAGASPTENMGIFQSLKHNIQKARDQAERRQLMQDNEKKLQESFKEKRQNSKIKIVHKSNFINNKK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . ... : .. :. . * : . : .:** * .::*: ** :* .:****:*. *: * :**: : .. *: : *:: : :: .: : : : .:.:: : : *: * *: :.** .**.*:: ** .: *: ** *** :** * : .:..: .:* ::. *: :: :*: :* *:::.:*:. *: .. :*: *. ** ** ::* : . * : . : . . *:. . :: . * :::. . ", "identical_positions": 56, "similar_positions": 114, "identity": "10.94%" }, { "cls_id": "homologset.agr.SGD:S000000957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811M1-1", "uniprot_id": "RHG15_MOUSE", "id": "Q811M1-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQ--------------------TSTNCDNSLEI-LNSAHQATGAVQMR------------------------------------------------IKNANSHQ-DRQSQTKSMILTDAG------------------------------------------------------------------------------------------------KVTEPISRHR-RNHSQHVL---------------------------------------------------------------------------KDVIPPLEHPM----------------------------VEKEGYLQKAKIADGGKKLR--------------------KNWSTSWIVLSGRKIEFYKDSKQQALP---------------------------------------------NMKTRHNVESVDLCGAHIEWAK-EKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGS--LELFNLQRSSSSELPS--HCHIDR--------------KEQKPEHRKSFMFRLHHSASDTSDKNRVKSRLKKFISR-----------------------------------------------------------------------------------------------------------RPSLKTLQEKGLIKDQIFGSHLHTVCERE-HSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN----QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKI-----ETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVH-MVYQNQIAEFMLTEYDKIFSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYC5-1", "uniprot_id": "RHG15_RAT", "id": "Q6AYC5-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQ--------------------TSTNCDNSLET-LNSAHQATGAVQMR------------------------------------------------IKNANSHP-DRQSQTKSMILTDAG------------------------------------------------------------------------------------------------KVTEPISRHR-RNHSQHVL---------------------------------------------------------------------------KDVIPPLEHPM----------------------------VEKEGYLQKAKIADGGKKLR--------------------KNWSTSWIVLSGRKLEFYKDPKQQALP---------------------------------------------NVKPRPNAESVDLCGAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFGS--LELFSFQRSSSSEQPS--HCHIDR--------------KEQKPENRKSFMFRLHHSVSDTSDKNRVKSRLKKFISR-----------------------------------------------------------------------------------------------------------RPSLKTLQEKGIIKDQIFGSHLHTVCERE-HSTVPWFVKQCIEAVEKRGLEVDGIYRVSGNLATIQKLRFIVN----QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSDAKI-----ETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTLLRAENESGNVAVH-MVYQNQVAEFMLTEYDKIFSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53QZ3-1", "uniprot_id": "RHG15_HUMAN", "id": "Q53QZ3-1", "name": "Rho GTPase-activating protein 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQ--------------------KSTNSDTSVET-LNSTRQGTGAVQMR------------------------------------------------IKNANSHH-DRLSQSKSMILTDVG------------------------------------------------------------------------------------------------KVTEPISRHR-RNHSQHIL---------------------------------------------------------------------------KDVIPPLEQLM----------------------------VEKEGYLQKAKIADGGKKLR--------------------KNWSTSWIVLSSRRIEFYKESKQQALS---------------------------------------------NMKTGHKPESVDLCGAHIEWAK-EKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRNLELFKIQRSSSTELLS--HYDSDI--------------KEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITR-----------------------------------------------------------------------------------------------------------RPSLKTLQEKGLIKDQIFGSHLHKVCERE-NSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN----QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRI-----EAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIH-MVYQNQIAELMLSEYSKIFGSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S8J8-1", "uniprot_id": "B0S8J8_DANRE", "id": "B0S8J8-1", "name": "Rho GTPase-activating protein 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQ--------------------KPP------------ALVLPGAVQLR------------------------------------------------IKNSQSSTGERLSQTKSMVLPEAE------------------------------------------------------------------------------------------------TLQKPINRHR-RNQSQHN----------------------------------------------------------------------------SEVSVGLQP------------------------------VLKGEYLNKAKIAEGGKKLR--------------------KNWTLTWVVLSSNQLLFYKESKQEAVS---------------------------------------------NLKPGGKPDGVDLNGAVIEWTT-EKSSRKNVIQITTPTGHEFLLQADHFPTISKWHDAIKKAVDILSSGSGGQS--CGRAALHRSNSTECLSRPTCESSKPK-----------PKETKSEHRRSIMFKLNYSASDSADKNGVKNRLKKFISR-----------------------------------------------------------------------------------------------------------RPSMKTLQEKGIIKDRVFGCHMLTLCDRE-KTTVPKFVKLCVEEVEKRGLEADGIYRVSGNLAIIQKLRFLVD----QEEELDLGDSQWEDIHVITGALKMFFRELPEPLFPFRFFDLFVETIKIKEPTQKV-----QAMKKLIHQLPKPNHNTMKLLFHHLRRVLTKSQKNLMSTQGVSIVFGPTLMWPEFESGNMEVN-MVYQNQIVECILIGCVEIFGPADK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C0D4-1", "uniprot_id": "RHG12_MOUSE", "id": "Q8C0D4-1", "name": "Rho GTPase-activating protein 12", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAERSG----KITAG---QAYIEVEYDYEYDAKD-RKIVIRQGERYLLVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIRDAN---QNFGSNYNSGQ-TLNLSLDLTHNNGKFN--------------------SDSHSPKVSSQNRTRLFGHFPGPE------------FLDIEKTSFSQEQSCDSAGEGSERIQQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYAN-----------------LQELKISQSALPPLPGSPAIQ--------------------VNGEWETHKDS-SGRCYYYNRTTQERTWKP-----------------------------------------PRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSE---ELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK-----------------------------------------------------------------DSPTTTKLCLPENESP-----------PTS--SKHQDPG-----QEKYGLLNVTKITENGKKVR--------------------KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEA------------DEAAEEETPDSPGVEKHD--------------KEKDQKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTR-----------------------------------------------------------------------------------------------------------RPTLQAVREKGYIKDQVFGSNLANLCQRE-NGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVN----HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV-----TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVH-TVYQNQIVELILLELSTVFGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDI5-1", "uniprot_id": "D3ZDI5_RAT", "id": "D3ZDI5-1", "name": "Rho GTPase-activating protein 12", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAERSG----KIASG---QVYIEVEYDYEYEAKD-RKIVIRQGERYLLVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIRDAN---QNFGSNYNSGQ-TLNLSLDLTHNNGKFN--------------------SDSHSPKVSSQNRTRLFGHFPGPE------------FLDIEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYAN-----------------LQELKISQSALPPLPGSPAIQ--------------------VNGEWETHKDS-SGRCYYYNRTTQERTWKP-----------------------------------------PRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSE---ELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK-----------------------------------------------------------------DSPTSTKLCLPENESP-----------PTS--TKHQDPG-----QEKYGLLNVTKITENGKKVR--------------------KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEA------------DEAAEEEAPDSPGVEKQD--------------KEKDQKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTR-----------------------------------------------------------------------------------------------------------RPTLQAVREKGYIKDQVFGSNLANLCQRE-NGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVN----HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV-----TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVH-TVYQNQIVELILLELSTVFGR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWW6-1", "uniprot_id": "RHG12_HUMAN", "id": "Q8IWW6-1", "name": "Rho GTPase-activating protein 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMADRSG----KIIPG---QVYIEVEYDYEYEAKD-RKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLP--ELSSFGKPSSSVQGTGLIRDAN---QNFGPSYNQGQ-TVNLSLDLTHNNGKFN--------------------NDSHSPKVSSQNRTRSFGHFPGPE------------FLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYAN-----------------LQELKISQSALPPLPGSPAIQ--------------------INGEWETHKDS-SGRCYYYNRGTQERTWKP-----------------------------------------PRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSE---ELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDTNDK-----------------------------------------------------------------ESPTASKPCFPENESS-----------PSS--PKHQDTASSPKDQEKYGLLNVTKIAENGKKVR--------------------KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVET------------DEGIEEEIPDSPGIEKHD--------------KEKEQKDPKKLRSFKV-SSIDSSEQKKTKKNLKKFLTR-----------------------------------------------------------------------------------------------------------RPTLQAVREKGYIKDQVFGSNLANLCQRE-NGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVN----HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV-----AAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVH-TVYQNQIVELILLELSSIFGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GV37-1", "uniprot_id": "A0AC58GV37_DANRE", "id": "A0AC58GV37-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSERDGRCDLSIAPG---QVYIEVEYDYEYKAKD-KLISIRQGECYMLVRKTNEDWWQVRREEGTKAFYVPAQYVREVRR-ALMPPPKPRAKPPN----VLEITHCRSSNENLNQRAPTEKSTFGRPPPSTTPSPLPGQQTPPLLLRDSNHNPGMKSVVAELTLLNNNNHHN--------------------FHHANPTLP-QGRAESPPRDQGCQ------------GKLTGGLSVDTDGSVS-PGDGVEKMRNDSESGDELSSSSTEHIQSVSLSGQGRPESPVYTN-----------------LQELKICQSSVPPVPSTSPLH--------------------VLGDWETHKDT-SGRNFYFNRTTQERTWKP-----------------------------------------PR-SRDNGVSRGDTSNTGDMEPLSSEENCPSTHSSQSDSQYGSPPRGWSE---ELDEHGHTLYVSEYTNEKWIKHVDEQGRPYYYSADGSRSEWELPKYNLSPP------ISGEAPKSHSLERKQQEPIVLTK-WRHSTYVLDISDKTTWFYLFA--------------------------------------------------------NKKLPFKNRWFSVNHPP-----------RGFGLPVYREPS------EKCGVLNVTKITEHGKKVR--------------------KNWASTWTVLQGSSLLFAKGQGSG--TSWSYCHNGSFPELLLSLLSNWKRSIKPRPAVSYTHCRRARASSFGGNQ-SKPEFTVDLRGGSVEWASKEKSSKKHVIELKTRVGTELLIQSEIDSVINDWFRALSETINTHAWES------------DEAIEEDMPESPGSEKHD--------------KEKDPRDSKKNRVVKN-SSMESSEQKKTRVKLKKFLTR-----------------------------------------------------------------------------------------------------------RPTLQAVRDKGYIKDQVFGCSLTALCQRE-GTSVPNFVKMCIEHVENTGLNVDGLYRVSGNLAVIQKLRFAVN----HDEKVNLDDSKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKNSDYKQRV-----QSIKDLIKQLPKPNQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLRPEIETGNMAVH-MVYQNQIVELILLEYENIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QA49-1", "uniprot_id": "A0A8M9QA49_DANRE", "id": "A0A8M9QA49-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADR------SIAPG---QTYIEVEYDYDYKSKD-RLITIKHGESYLLVKKTNDDWWQVRKDDASKPFYVPAQYVREVRR-ALMPPPKPLNIAGRGGPAPNRPSALEIQRPNDNKKS---------PCPSPSSTALLPPRD----DRGSPVSPTR-HLPPAQMNTFPGSLPC--------------------FRAESPGSKLDGERD---KDKDSE------------RKDRGEKAAVQEELAEEGGDS-DKNRIDSESGDELSSGSTDNLQSLG-SGQGRPDSPVYTN-----------------LQEMKISQSSTPPLPSSSPIH--------------------TNGDWETHKDQ-NGRHYYYNRSTQERTWKP-----------------------------------------PR-ARDSLPRKEEKHDMTDTEVLSSEENCLS---SQSDSQYGSPPRGWSE---EMDEHGHTLYVCDYTNEKWLRHTDERGRLYYYSADGSRSEWELPKIGLKSQSNHTPLMPGDLHKTRSLDRRLPDPIPISRTQRHSIYSHETNDKLKQKFVKVRQSFL-------------------------------------------------PRRKTTLRSHPYFPQDTKTGS---------PDSDSSCPSSPKPPHSPSEKCATLNMTKITEHGKKVR--------------------KNWTSYWTVLQGSLLIFNKGQGGG--SGW-----------------------------------------FGRDQKSSVEYSVDLKGGSVDWASKDKSSKKHVLELKTRQGTELLLQSDSDGLVNDWHKALTEAIHTYMWES------------DEAIEEDMPESPENEKHD--------------KEKDRKNSKKARDIKKTASMDNAEQKK-KNKLVVLLLG-----------------------------------------------------------------------------------------------------------RPTLQAVKDKGYIKDQVFGCSLSSLCQRE-NSTVPRFVWLCIEQVEKNGLGVDGLYRVSGNLAIIQKLRFAVN----HEEKIDLGDSKWEDIHVTTGALKMFFRELPEPLFTYTFFSDFISAIKMPDYKQKV-----QTVKDLMKKLPRPNHDTIQVLFKHLKKVIQHVDENRMTTQSVAIVFGPTLLRPEIETANMAVH-MVYQNQIVELILMEYDTIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B2D3-1", "uniprot_id": "A0A8M2B2D3_DANRE", "id": "A0A8M2B2D3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPDPLFAPQHVWATMSLSQQVLVNYEYTYTARDGRNVSIKPNEHYILVNKTNEEWWHVQKDAADKPFYIPAKYVTELPPETSQTPLDPPEEFSG--YESLQFGSQTADPAEVTLRVPDSIKRDTEKDGHRISTFIIPKEFFELKGLDPDPIKTEAEAGPPVSSNTSSPTNG-------------ETAFIILPPPVYTVNTTQSTETDTRSVDDP--------KDSVGRPRVDSSTIDEDIQMLNRAGWSEVLDVMGKEKNVYESLDTVREPES---PKDEADMTVNTTPVTPDAPMVEDD----TAVYVNIPRKRQTTINNSSPIASLLQD-----FPEPPENFLLDSAGWQVHTDDQSGQEFYYQPSTGRSTWENPLSSRSM-------------------ESPVGTEGGRSPPSFPQSPACSPVAPAPRRWSSDWEKVLDESTGRHYFFNTVSGQSSWDPPE------DVDSPGRLMFLDDCPPPLPEEDYPASPELEEASPVSIPAEYSLIHVKKVSIPRVSLD--RSSPAGWSLDIDSEGTWTFTSEYTQEQWIKSLDDQGRTYYYLRDGSKSQWNLPEINPGQGGVAAQWLALLPYSKNVAGSSPGWYSASPGQYGVGNGASGEQDTVGSNWRHSAGYPDDKNHSSYIQNTSDSEASSSPDTPHNVSNLEKAGILNKTKVSENGKKVR--------------------KNWGHSWTVLHGGKLTFHKDPKSTPAG------------------------------------------ASSKTNQILPEFTVDLKGATINRAPKDKSSKKNVLELKTRTGAEYLIQYDTDSIIQDWHKVILDTIHQLNGDQHHS----------EEEDEVIDKSPTLDREER------------PFE--KRTMSTATRQPSTSSTSEAEQKKVRTKLKKFLLK-----------------------------------------------------------------------------------------------------------RPTLQSVKDKGYIRENVFGCHLHNLCSQE-KTRVPSFVEKCIRAVEKRGLEIDGLYRVSGNLAVIQKLRFKAD----HED-LDLEEGNWD-IHVITGALKLFFRELQEPLFPYNLFNEFICAIKTPDYYSKI-----SHMRNLVRSLPPPNHDTMEALFSHLRRVIQHGNENRMTVQNVAIVFGPTLLKPEEETASIATY-MVFQNQIVEFLLSEFESIFHM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B765-1", "uniprot_id": "A0ACD6B765_DANRE", "id": "A0ACD6B765-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGETGKMTSVHTLG------LVLVEFEYEYEGRDGHMVCIKPNERYILLAKTNDHWWHVCKDERAKPFYIPAKYVKELPPN-IPSPLDYREPPGPDVKPAVPDLTETRKADEVTIRLRS--KGNYHKTENRMSTFGVPLDLHEPPSYKHGGPSDSLISLSSVSASDSSKQKKRMSHAPNLLFGSHSNLPTELVPDKFRVPSFSPADPLHRPIPAKPVEIPIIKNLNETKPHRTSPELESPIEPESESSSSEPMPSPDSE-NIYESISDLNIDLSSLTDKEPAGLPDTQTTTSSLPPSIKTDNDPTTALYANVADIKKNIPRSSNSSVSTCSSPGITLSPAPDSISPPSSAEWRVHTDHDSGKEFYYHPATGQSSWSDPRSP----------------------QPGAGMESVTAP-----VPASSP--PSAR---SDWEQLLDEATGRHYYYNHASNKTSWTAPEPSAPASSKQGPHSQDKDKERPPPLPEEDYPKNQHEESHISFQLPKDFQLPQIKRAVIPRAVMDTNKDVPTGWTQSVGTDGKSVFTSELTHEQWIQSKDEKGKLYYYSKDGSKCQWTLPEALVPPGQPMNGNGVEQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIASDNASDASSSGNSPESQHYDKKFRRRRN-LSSYSTDSHSHHSSLEKAGILNKTKVAENGKRLR--------------------KNWAQSWTVLHDGVLTFHKDPKFAPAG------------------------------------------MSSKTNQIVPEYTVELKGATLSWASKEKSSKKNVLELKTRHGSEYLIQYDTDSIIQDWQKIILDTIKLLHEHGHNS----------EDEAEDVP-----EKSPL------------PAD--KEKKPEAARLSSTSS-IDTDQGRVRTKLRKFLQR-----------------------------------------------------------------------------------------------------------RPTLQSVKEKGYIKENVFGCHLDTLCHRE-NTTVPKFVEKCIRSVEKRGLKIDGIYRVSGNLAVIQKLRYKAD----HEEDLDLEDGQWEEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQISDYSQKV-----SYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLRPQEE-SNITMH-MVFQNQIVELVLNEFNELFQTK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEG----DVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQR---PAVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTGGQRNSLAPG--------------GPACLYVRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLAPSDSE-NVYEAIPDLRCPPRAESPKQVDDPPE--------------------PVYANVERQPRATSPRSAAAP------------------PRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFET---------------------------PEGTTSP------ATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEEL---EEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASP--LVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPR------------------------------------SVRKSSQDSDTPAQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRK-------------------KHWSTSWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQG----------EEGEPSSADFGSSERLGS------------WRE--EDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQR-----------------------------------------------------------------------------------------------------------RPTLQSLRDKGYIKDQVFGCALAQLCERE-RSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVD----HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS-----RCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMT-MVFQNQVVELILHQCADIFPPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEG----DVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPSVLQQR---PTVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTSGQRNSLAPG--------------GPACLYLRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLARSDSE-NVYEAIPDLRCPPRAKSPKQVDEPPE--------------------PVYANVERQPQVTSPRSAAAP------------------PRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA---------------------------PEGATSP------TTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEEL---EDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSP--LVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPR------------------------------------SGRKSSQDSDTPAQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRK-------------------KHWNASWTVLEGGVLTFFKDSKTSAASG-----------------------------------------LRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELSADLPQR----------EEGEPSSADFGSSERLGS------------WKE--EDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQR-----------------------------------------------------------------------------------------------------------RPTLQSLREKGYIKDQVFGCALAQLCERE-RSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVD----HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS-----RCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMT-MVFQNQVVELILHQCADIFPPH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVVG----DVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGNPAAAAPP-GPHPS---PAAPEPLAYDYRFVSAAATAGPDGAPEESGGRASSLCGP-------------------AQRGAATQRSSLAPG--------------LPACLYLRPAAPVRPAQSLNDLACAAVSPP------------AGLLGSSGSFKACSVAGSWVCPRPLARSDSE-NVYEVIQDLHVPPPEESAEQVDDPPE--------------------PVYANIERQPRATSP-GAAAA------------------PLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA---------------------------AEGAASP------ATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN------EPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSP--LTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPR------------------------------------SIHKSSQDGDTPAQASPPEEK-VPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRK-------------------KHWSASWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPP-----------EESESSRVDFGSSERLGS------------WQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQR-----------------------------------------------------------------------------------------------------------RPTLQSLREKGYIKDQVFGCALAALCERE-RSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVD----HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRS-----RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMT-MVFQNQVVELILQQCADIFPPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15882-1", "uniprot_id": "CHIN_HUMAN", "id": "P15882-1", "name": "N-chimaerin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALT----------------------------------------------------LFDTDEYRPPVWKSYLYQLQQEAPHPR--------------------------------------------------RITCTCEVENR---PKYYGREFHGMI------------------------------------------------------------------------------------------SREAADQLLIVA-EGSYLIR---------------------------------------------------------------------------ESQRQPGTYTLA--------------------------LRFGSQTRNFRLYYDGKHFVGE-------------------KRFESIHDLVTDGLITLYIETKAAEYIAKM---------------------------------------TINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPK--------------------------YEKIHNFKVHTFRG-----------------PHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSK-----------------------------------------------------------------------------------------------------------MVPNDCKPDLKHVKK-VYSCDLTTLVKAH-TTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR---DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQL-----ETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30337-1", "uniprot_id": "CHIN_RAT", "id": "P30337-1", "name": "N-chimaerin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSKESWSG--------------------------------------------------RKTNRATVHK----SKQEGRQQD----------------------------------------------------------------------------------------------------LLIAA-LG----------------------------------------------------------------------------------------------------------------------MKLGSQKSSVTIWQPLKLFAYS-------------------------------------------------------------------------------------------------------------------------------------QLTSLVRRATLKENEQIPK--------------------------YEKVHNFKVHTFRG-----------------PHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSK-----------------------------------------------------------------------------------------------------------MVPNDCKPDLKHVKK-VYSCDLTTLVKAH-ITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR---DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQL-----ETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03070-1", "uniprot_id": "CHIO_RAT", "id": "Q03070-1", "name": "Beta-chimaerin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLCTSPVNC--------------------------------------------------LDSVCCTSIN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISSLVRRAALTHNDNHFN--------------------------YEKTHNFKVHTFRG-----------------PHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSK-----------------------------------------------------------------------------------------------------------HVPNDCQPDLKRIKK-VYCCDLTTLVKAH-NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR---DGEKADISANIYPDINIITGALKLYFRDLPIPIITYDTYTKFIEAAKISNADERL-----EAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W4A9-1", "uniprot_id": "Q9W4A9_DROME", "id": "Q9W4A9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRNTEAGAGNANTGGSGGVGG----------------------------------------------------APEPSSPVQKVWKPELYKLQLEAPAPCPLRCQRT--------------------------------------LPLPPAKSTAEAVEANNLAGRLYGSEYHGLM------------------------------------------------------------------------------------------GHLEAEQLLANARDGSYFVR---------------------------------------------------------------------------RSPQSDGYYTLS--------------------------LRFNKRPKHYKLLYKPGVGHYL-------------------RGQDKRFDTVHDMVADGLIN----------------------------------------------------------FHMQLHASPIIQQINQQTKNCYQQSPYMTLNGRKLRALSNELGKAAAKESKESPAEEKEQKQEEPPPP-----AVDPMPLVYEKPHHFKVHTFKG-----------------LNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSE-----------------------------------------------------------------------------------------------------------LVPPKCVPDLKRIRG-VFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDR---EGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQR-----QLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATP-----QHMTNLTEEIFMLSSLITHCKTIFATS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39960-1", "uniprot_id": "BEM2_YEAST", "id": "P39960-1", "name": "GTPase-activating protein BEM2/IPL2", "aln": "MKGLLWSKNRKSSTASASSSSTSTSHKTTTASTASSSSPSSSSQTIRNSTSGASPYMHSHHHHGQGHSHHRGEDNNRDKRKSSVFPPSKQYTSTSSSQVNLGMYHSDTNTRSSRSIASTLKDDSPSVCSEDEISNSSSQKSNAQDETPIAYKKSAHSKDSLLPSRSSSLSPPQSRCSTGTTLEKSLNTSGISNSSGTNNNNSNNNNDNEQKQRNVIHLNSENYDTTVFKTGWVNKSHGQTVATNYNSSMTAPSSSSSSSSQNLRNDAYSRNRESRFYGNDGSSLKNDDSSSTTATNSGNDVASARSSMAIDPQMLVPDYRLYRAQLKGCVLNLYKSGLNSNIKFFDPTLPASNSSIANENHQQKKQQTNNQAQAEALHQKQSFGQMGEPITLDLKYLSEVYPHPDLRQDSDGKIISGTIESLCHTVLFYPGPKQSDVPNEKSLSKTHRAVINLLLMFPLLDHFIKFLKVFNQFGLSFTKNKSRLTNNSTQFYNISPAVDDSMTQRLALTAKTILDVFPGFLLDEPMLKTIISLLDTISLHNDEISNNLKIKIANKHNELMKLTAFTRSLPMATSSTHELEIILDPSHFLSLDITTLADEVHHINLKFDKVWAPKFDYSLLYDSKFINRRIVSLNPLVFNNDQNIHFLGRLLISHLFPTNPEFSKKVTPKVRAELLDKWVQIGCRFEHLGDMVSWLAVATIICSIPVLRSSSWKYVPDQSLKTIFKDWVPTIIQLERRQRTSKSTSSVFILAPPNLDDDFTRANVISYFGDLLIHADDLPSDTKFKYLEKKINRTKNAFHKWQQRLQAIDSTRHKTNSTENVRDNDSPNNVVYQLWKFHLSQPPLNIEGIMKLSVQHEPPIIDQKAYSTIGSQRSALVTGSYLPILFNELFPNYSLFPKNTLVGAASDAKLPPPRSSARLSKSLSISEPIPIASNSHTMGSLTDDAMSSKNDNNKVTGVGKIDGPVIKEMSSKQSNKQRLLKSVRDVFNIDMDVFHISDELVFKSVYDNDGKSRPASMVIETPKRFSQHSSMLINNPATPNQKMRDSLDTTGRLSKTLENMDFFNNIGQVSDSLKESIIRVVLKSSSLEKIFDLLVLTSN-IFSKLVDTKDLENYYYHQRQRGHSTRGLSDDNIGLLDYAFVKLTMDNDIFTETFFNTYKSFTTTTTVLENMAKRYVGAKSCSVSISKILDRSDDSKMKINEDTNLVSSSLYDQNFPVWDMKVTDDENINLIYMAKIQIGAAEAILHLVKNHYSDFTDDLCNNSTLLDIIKIMEQEVSTEWPTRIANSKLQKSLPENFVIETENLLTTLTDLFHGIKSAYQKQLYRPIGVNRTQKRITDILNSFNTFSFTDLNNIIDDPSFSDDMIRSFQKLHSTNYEDILEWIYQLDNFISKKFNLVSKKDWIVLFQELELLSKESLVSFFNYPLHFKSSKLINPGYLQLHEFEISNLFTWISTLILKDDNGTESLFFEKLPQSIKLLIKLHTSLTTFFVMEISNVNKSSSERLTTCKVILQILN---YIRWKNGSLDLFDSEEDESPHAICPHIPAFIETAIAHAIISPESRNYELSWIKASEKLSDPTKGTQNLRSISNVLEKIDDIHIKRFIEIDDVFSKNCKNLCPCPGWFISRLLEISQFVPNMSITNSKLINFDKRRFVNNIISNVLDLIPNEREFPLDIEMSDENPSKRTTFG---------RILFNNFEDVNKVYRKKTKKVSESEAISERFQEQGVFNEILVNEIEKIKREARKLEVLLDQEKILKNSAALHQAVPKKN---RKSVIISGTHSDNDHSYNINKNTGQTPSLGSVMESNNSARNRRDSRASFSTNRSSVVSNSSHNGVSKKIGGFFRRPFSIGGFNTSSSNYSLNSILSQEVSSNKSILPSILPEVDSMQLHDLKPSYSLKTFEIKSIMEIINHRNIPAYYYAFKIVMQNGHEYLIQTASSSDLTEWIKMIKASKRFSFHSKKYKGKTHNKIFGVPLEDVCERE-NTLIPTIVVKLLEEIELRGLDEVGLYRIPGSIGSINALKNAFDEEGATDNSFTLEDDRWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKAHAMVNEEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFINQEDLANSMGSR-LGAVQTILQDFIKNPNDYFKQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : :: : : . * .* :. :* *: *:**:.* *: :: : : : : :: :* :*: :* * .::.. * . : . : ** . :. :. ** :: : * * . . **. ::: : . .: * ", "identical_positions": 23, "similar_positions": 57, "identity": "1.05%" }, { "cls_id": "homologset.agr.SGD:S000000958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641W2-1", "uniprot_id": "MYG1_RAT", "id": "Q641W2-1", "name": "MYG1 exonuclease", "aln": "MGRGFLRGVLTLLPLRSVLQVQHCMLVSEPDLPPKRPRNNLMAPPRIGTHNGTFHCDEALACALLRLLPEYRNAEIVRTRDPEKL-ALCDIVVDVGGEYNPQRHRYDHHQRTFTETMSSLCPGKPWQT---KLSSAGLVYLHFGHKLLAQLLG----TSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEG-----EPRY-ALTTTLSARVSRLNPTWNQPDQDTEAG--FRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPTVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATLAQRTAPVPLANAVVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK81-1", "uniprot_id": "MYG1_MOUSE", "id": "Q9JK81-1", "name": "MYG1 exonuclease", "aln": "MGRRFLRGILT-LPLRSVLQAQHRMLGSEQDPPAKRPRNNLMAPPRIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKL-ASCDIVVDVGGEYNPQSHRYDHHQRTFTETMSSLCPGKPWQT---KLSSAGLVYLHFGRKLLAQLLG----TSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEG-----EPRY-AMTTTLSARVARLNPTWNQPNQDTEAG--FRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPKVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATLAQRPAPVPLANAVVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB07-1", "uniprot_id": "MYG1_HUMAN", "id": "Q9HB07-1", "name": "MYG1 exonuclease", "aln": "MGHRFLRGLLTLLLPPPPLYTRHRMLGPESVPPPKRSRSKLMAPPRIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKL-ASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQT---KLSSAGLIYLHFGHKLLAQLLG----TSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEG-----EPRY-ALTTTLSARVARLNPTWNHPDQDTEAG--FKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFIGGHRTREGALSMARATLAQRSYLPQIS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40093-1", "uniprot_id": "YEY6_YEAST", "id": "P40093-1", "name": "MYG1 protein YER156C", "aln": "------------------------------MNSVKRVKLNSKMSKQICTHSGSFHADESLAVYMLRLLPEFKDAKLVRSRNPKDW-EASDILVDVGAQYDG-VKFFDHHQRGFFETFN-----EKYKT---KLSSAGLIFKHYGRDIIKTILN----NKVSSSDLDLLYDKVYKQFVEALDANDNGISKYTIPKDSNLEPNFRDNAISIPGIISGMNPNWNEDTSDESFDRCFARASEFIGGVFVTLVRGYGQSWLPAKALVAQAIDERMDVDKSGKIIVLPQ-FCPWKEHLYELEREKNIEKQIEFVLFTDSSGAWRVSTVPINSTSFQFRRGLPEPLRGLRDEELSTKSGVPGCIFIHAAGFIGGAKSKEAVYELAKMSLA--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8INP9-1", "uniprot_id": "Q8INP9_DROME", "id": "Q8INP9-1", "name": "", "aln": "MFRLLPR-------------------FPGKLSIMTGVTPPKRSPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSPENLQTAFIQIYRNFINELDAIDNGVPMFEGV-----EPIY-KISTHLSARIAKLNPSWQETGVDIEDR--FRQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVLKN-FCPWKSHLFDLEKEYKVEGVPKLVVFN-SGNSWRVAGVPVTPGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFIGGAKTEEAAMLLAKKSTEWTEEQ---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * **.*:**.** :* :*: * *: :*::.*:*: : .**:****. *: : :**** * **:. . :******:: *:*. :: :* . . . : : ::*.:*:: :** ***:. : ** : : :.. :: :**.*:. * . * :* : *: : **:**: * :*: : .*. :*:*: * : ****.**:.** . :*::. ... **: ** . *: * ** * *** *. * :.: . *:* :***** ::.*.. :*: : ", "identical_positions": 96, "similar_positions": 104, "identity": "24.18%" }, { "cls_id": "homologset.agr.SGD:S000000959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEZ8-1", "uniprot_id": "A0ABK0LEZ8_RAT", "id": "A0ABK0LEZ8-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "MFILGRKPRLFWPRSRPHAVEAFPGSGRSGPPRRGCGAGSPGPPGSSPALPVGLRFCVAEGPKAAGMAEASLLLLPEAAAERDAREKLSLWDRRPDSIAPLTDRQTDSVLELKAAVENLPVPAELPIEDVCSLASQSLPIELTAVVPESTEDVLLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILSDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELADLAEHIQQKLSYFNELETINTKLNSPT--LSVNSEGFIPMLAKLDDCITYISSHPNFKDYPVYLLKFKQCLSKALHLMKTYTVNTLQTLTNQLLKR-----DPSSVPNA-DNAFTLFYVKFRAAAPKVRTLIEQIEQRSEK------IPEYQHLLNDIHQCYLDQRELLLGPSIAYTVTELTSQNNRD-HCALVRSGCAFMVHVCQDEHQLYNEFFTKPTS--KLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILK-NEVLEDHVQNNAEQLG--AFAAGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKTPSEAS---FSDVRLEEGESSSLRKSGSTDSLNPRPQTTISPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKT------QIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTRLFVEPLEEFMTKVSALKTMASQGGPK--------YTLSQQPWAQPAKVNDLVATAYKTIKTKLPQTLRSMSLYLSNKDTEFILFKPVRNNIQQVFQKFHALLKEE-FSPEDIQIIACPSVEQAC-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI04-1", "uniprot_id": "COG3_MOUSE", "id": "Q8CI04-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "--------------------------------------------------------------------------MAEAAAERDAREKLSLWDGRPDSMAPLTDRQTDSVLELKAAVENLPVPAELPIEDVCSLASQSLPIELTAVVPDSTEDILLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILNDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELADLAEHIQQKLSYFNELETINTKLNSPT--LSVNSEGFIPMLAKLDDCITYISSHPNFKDYPVYLLKFKQCLSKALHLMKTYTVNTLQTLTNQLLKR-----DPSSVPNA-DNAFTLFYVKFRAAAPKVRTLIEQIEQRSEK------IPEYQHLLNDIHQCYLDQRELLLGPSIAYTVTELTSQNNRD-HCALVRSGCAFMVHVCQDEHQLYNEFFTKPTS--KLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILK-NEVLEDHVQHNAEQLG--AFAAGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKAPSEAS---FSDVRLEEGEASGLRKSGSTDSLNPRPQTTISPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKT------QIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTRLFGEQLEEFMTKVSALKTMASQGGPK--------YTLSQQPWAQPAKVNDLVATAYKTIKTKLPLTLRSMALYLSNKDTEFILFKPVRNNIQQVFQKFHALLKEE-FSSEDIQIIACPSMEQLNLLLSVSK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JB2-1", "uniprot_id": "COG3_HUMAN", "id": "Q96JB2-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "------------------------------------------------------------------MAEAALLLLPEAAAERDAREKLALWDRRPDTTAPLTDRQTDSVLELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTEDILLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILNDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELVDLAENIQQKLSYFNELETINTKLNSPT--LSVNSDGFIPMLAKLDDCITYISSHPNFKDYPIYLLKFKQCLSKALHLMKTYTVNTLQTLTSQLLKR-----DPSSVPNA-DNAFTLFYVKFRAAAPKVRTLIEQIELRSEK------IPEYQQLLNDIHQCYLDQRELLLGPSIACTVAELTSQNNRD-HCALVRSGCAFMVHVCQDEHQLYNEFFTKPTS--KLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILK-NEVLEDHVQNNAEQLG--AFAAGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKVPSEAS---FSDVHLEEGESNSLTKSGSTESLNPRPQTTISPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKT------QIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTKLFVEQLEEFMTKVSALKTMASQGGPK--------YTLSQQPWAQPAKVNDLAATAYKTIKTKLPVTLRSMSLYLSNKDTEFILFKPVRNNIQQVFQKFHALLKEE-FSPEDIQIIACPSMEQLSLLLLVSK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NPJ9-1", "uniprot_id": "A0A8M1NPJ9_DANRE", "id": "A0A8M1NPJ9-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "------------------------------------------------------------------MASSTDQNLLDLT-DKDTREKLSFWDRRVDPMAPLTDRQTDSILELRAAAEETLLPAELPIEDICSLSSRSLRSSFTAALPESTEEVLLQGFQMLELHNHRIETAQQFFSWFSKLQVQMDQDEASKYRKTQDVLNGYQEQCDAILNDVNTALDHLDSLQKQYLFVSTKTGTLHEACEQLLKEQSELVDLAESIQEKLSYFNELENINTKLNSPT--LSVNSEGFVPMLSKLDECIEYVSSHPNFKDYPVYLTKFKQCLSKAMQLIKSHTVNTLQNLTGQLSKR-----DPLGAPNA-DNAFTLYYVKFRAAAPKVRRLIEQVEQRSEK------IPEYHQLLEEIHQCYLDQREVLLSPSINSTITDLTSQNNKD-HCALVRSGCAFMVHVCQDEHQLYNEFFSKPTS--KLDELLEKLCLSLYDVLRPLIIHVVHLETLSELCGILK-NEMLEDHVQNNVVQLA--AFDAVVKQMLEDVQERLVYRTHIYIQTDIIGYKPAPGDLAYPDKLEMMEKIAQSLKEEQMKLNSSNS---FSDVQLEESENKKLISS------DTRLQSSVSPADLHGMWYPTVRRTLVCLSKLYRCIDRTVFQGLSQEALSACIQSLLHASDIIQKNKT------QIDGQLFLIKHLLIMREQIAPFHADFAIKEISLDLKKTRDAAFKILNPKAVPNFFRLNSHNAILEFLLEGTPEIKEHYIDSKKDVDRHLKLSCESFIQQQTLMFVGNLDQFLSRVGALKTMAVQGGPT--------YNLSQQPWAQPAKINDVVMSTYRVLKNKLPSTLQSMTLYLANKDTEFILFKPVRNNIQQAFQKLHALLQEE-YSGEDLQIIACPSMEQINLLLSVK-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q961G1-1", "uniprot_id": "COG3_DROME", "id": "Q961G1-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "-------------------------------------------------------------------MDDVERIQSENENLRKIRNRLMQWESKTDPLAALSIQQEEHLDVLTNLWRDSGPSAPAPTTPTQVGPTDSS----AAATSQSGDDIRLP--------AEGLQNTNEFLLWFADVSAEIEQRGDADYHKYLQQLEQRKAECSHMLDQIAGAMERLGALCDEYDFVSQKTSALNTASEQLIEEQERLQELSHEIQRRLHYFSQVELLNQRLQSPT--LSVASEAFRECLNKIDECLNYIEENPKFKDAAAYNVKYRQCLAKASGLVRNYVTSVINQATEATLHPKNNMPDASAALKAPDAAFALYYGKYQTAAAKVKRVAQLIESRSEH------SLDYAQLMADLQQHYLAQRASVMSPAVNLSIQNVKVAHKGD-HCSLTRSACAFLVHVCQDEQRLFYQFFSTGAP--HLTVYLEGLCTILYDTMRPFIIHINHLETLAEICSILR-IEMLEEHVQQNPVALE--AFATIAHQLLQDVQERLVFRAHLYLQSDIQNFNPSSGDLAYPEKLEMMESIALSLQEP---APLRRS---DSRNSMVSSVSSAVETESVATAYTVKQMN--SPADLHGMWYPTVRRTLVCLSRLYRCVDRPIFQGLSQEALKLCIQSVSHAAGKISANKT------PIDGELFEIKHLLILREQIAPFRVDFTVKETSLDFSKVKTAAFGLLQ--KRKQLFSMGSNNALLEFLLEGTPQIKEHLLDSRKEVDRQLKSVCEKYIKDAVQMLVGPLITFLEKAQSLLAQSTPATPQSPESTKASYVLRQSPWASPQQISSIIQETQRLIKAKLAVLQRSMQLYLSNRDTEFIIFRPIRNNIIQSFVKLEQLLTTNGYSTDDMIITSCPSAEQVSILLSSASILAAEGVASFAAAARKISTSSSVEGSTVGRKLSAMSNKSELVEEPKVEEVAGQIEVVPAEVQPPAKIEEEEVTETQTQANSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40094-1", "uniprot_id": "COG3_YEAST", "id": "P40094-1", "name": "Conserved oligomeric Golgi complex subunit 3", "aln": "-----------------------------------------------------------------------MARSRKNSLVRDIASHPTIPESQTIVGLLDDSYLFDKLKKLSLAVENSDSLQRTDVSEGCSEVNGSEATTSADVKKTN---------------------------------------KYLYYTTYLDQLNIKIDEYKVVLDQTRQVNDQLDSSIKKFRKISQDTGAFIEETKTIYEKQSKLSNLTESIPKALHYFEVLDPIMRRLNHATSPAIVKKSSFTTMLATIDESLRFLDENSDLKDAAAYRIKFKQCLIRACELISHFLTNLLKQTNQEILDKTKNKNSLTGLPST--TRDAFLYSKFYTIADTFKIQVSEIVKRSNEKAYNKYHDELNSILYECFNHYFQTRLRLLTPVIWSHIDEIVVKDKDQGLVKFIQDGKVYFQQLCADEYKLFVEFFPEKECRFKINQWFLQLCEPLYDSIRVRVLKETDICTLCDSVTLFAPYYEFEEGSEEYVKQFTDIQYDKLFEPIVQKVQARLILRVQIYVQQNILSYRPTRDVFMISNRRRKSKTSLQGGNEDATTSDDNPDPLLESYLSSFKNRSILPISPNDADDKSIDSEESTDKISQLQTYYPPLLKTLALLSKIYEMINSVVFDDLAHHVVHDCIVSLRNAYDMVIKSSAGKSDFNNLDISLAYLKNLLMLRDSIQNFNIQYTVNETYLDFSGVEGFFKSLKE--NGRNVLKKTKSSSILTLARELVPKVVNNMVDARTELISELRNVIKDFTESTSLELIDDTLDINSDEDLLSKNVKLREN-----------IKARLPRIYEQILNYIDDQEIVTNLLDAVQELITQSYSKYYETITELAENGKFAKDQVADVMYLDVFTDFFAKEVADLLRNGDIDTITK----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .: : : : : * .: . * : . . * : *. : . :*.: . ::* : .:: :* .*.:: : : ::*..* :*:. * . * **. :: : :*: .* * ...* * .:*:.: ::..:..:** . * *::*** :* *: . .. :: . . . . .: :: * *: : * ..: . : **:. : :: : : *: * :: * : : :: .: : : :.. .:: ::* ** :*: :**. :: : ** *** :* ::: .: **.: :: :*: :. : : . :::.** **: *.::*:* :* .:.*: . : .:: : . :: . * .. . . . :**.: :**. **::*. :: :*:.*::..: ** *: * : ..: :* .* :*:**::*:.* *. :::::* **:. .. : : ..: . .::: : * .*:: :: :*::.:: .*: :.: :. : : * : :: . : . * :* : . : * : : : :: : : . : ", "identical_positions": 95, "similar_positions": 262, "identity": "9.37%" }, { "cls_id": "homologset.agr.SGD:S000000961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPP1-1", "uniprot_id": "NC2A_RAT", "id": "A0JPP1-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHTDGDK--------GPRRGRKPGSSGRK-----NGGTGS----KSKDKKLSGTDSEQEDESEDTDTDGEEETPQAPPQAS---HPPAHFQSP--------PTPFMPFTS-------------------------------------------------------------------PLPLPPAPPG-----------------PSAPEA---------EDEEDYDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6N5-1", "uniprot_id": "NC2A_MOUSE", "id": "Q9D6N5-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHVDGDK--------GPRRGRKPGSSGRK-----NGGTGS----KGKDKKLSGTDSEQEDESEDTDTDGEEETPQLPPQAS---HPPAHFQSP--------PTPFIPFTS-------------------------------------------------------------------PLPLPPAPPG-----------------PSAADA---------EDEEDYDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14919-1", "uniprot_id": "NC2A_HUMAN", "id": "Q14919-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHMDGDK--------GARRGRKPGSGGRK-----NGGMGT----KSKDKKLSGTDSEQEDESEDTDTDGEEETSQPPPQAS---HPSAHFQSP--------PTPFLPFAS-------------------------------------------------------------------TLPLPPAPPG-----------------PSAPDE---------EDEEDYDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2E3-1", "uniprot_id": "Q9W2E3_DROME", "id": "Q9W2E3-1", "name": "", "aln": "-------------------------------MPSKKKKYN----------ARFPAGRIKKIMQSDEEIGKVAQAVPVIISRTLELFVESLLTKTLRITNARNAKTLSPSHMRQCIVSEKRFDFLKELVRNIPDISVAEEAAYNEDDVLRSSPEEQYPDSDTPYDLSLPSTSMRSQANGTAAYMRSMSLNNGAGSGGGAAATKRQFQSQHSTQETPTTSTTLPAKLARSGSMPAYTPRGRPPNHLKKQSVQLDTAIPAPICNYELNKPIVKIDYSHVQMPTANLCTPDASDSGSGSGAGSGAFNFDIAAPVINIDLTNIVAGGAPGSGVPPASIGLPAATPGDNNNVNQMAGKSSAPIIPKATAASATPTETVFELDEDYDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40096-1", "uniprot_id": "NCB1_YEAST", "id": "P40096-1", "name": "Negative cofactor 2 complex subunit alpha", "aln": "MADQVPVTTQLPPIKPEHEVPLDAGGSPVGNMGTNSNNNNELGDVFDRIKTHFPPAKVKKIMQTDEDIGKVSQATPVIAGRSLEFFIALLVKKSGEMARGQGTKRITAEILKKTILNDEKFDFLREGLCVEEGQ---------------TQPEEESA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::.:: * ::**..::*****:**:****: *.*** .*:**:*: *:.*: .::..:.:* ::.. ::: * :::****:: : . . *:: ", "identical_positions": 32, "similar_positions": 47, "identity": "8.38%" }, { "cls_id": "homologset.agr.SGD:S000000964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3D8-1", "uniprot_id": "D4A3D8_RAT", "id": "D4A3D8-1", "name": "p125", "aln": "--------MFQTLRPFHLSREQTLGNVGPPRTGRRTTLFLSLRALVVCMG-----AGFFGGRGPIRSWGCGQAWHASGRSRHAETFGSPAWLSGGTPLASMARKRTAGGK---RRKRGQEAED-------NKATRPEESDADDFEDEKQKPPRKCFLPKVSQGKRKRDCSDPGDPTNG-------------------------------------------AAKKKVAKATTKSKNLKAVKEEALSDDGDDFRDSLSNCRKAKKHPKREVVD------QGTDEDD--SEDDWEEVEELTEPVL--------------------DMGENSATSRSDLPVKAVEIEIETPEQAKARERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLLASGFYRNSICQQPD-LLAIGLSIIPIRFTKVPLQDRDVYYLSNLVKWFIGTFTVN-----ADLSASEQDSLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVAK----------------------------------GKKSSKETSLEGPGDSSEPSSNIPESHNKPKTSKRIKQEETLSEGSG---------------------------------------------------------------------KANARGKRGTATAGSRQQRKPSCSE-----GEEAKQEIQSHPQAQ-----------------KRRVAAKVSYKEESESDGAGSGSDFELSSG----------------------------------EGQHSSDEDCKPGPRKQKRASAPQRSKAGSKSASKTQSGSQWEPPSFSVASSSS-------------------SACKRGKKISCGGEETD-----------------------------------------------------------------------DRKAAGVDQWLEVFCEPQAKWVCVDCVHGVVGQPVACYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLR------PYRSPLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPESAAVLGYCRG-------EAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDHNDLGLFGHWQTEEYQPPVAVD-GKVPRNEFGNVYLFLPSMMPIGCVQMNLPNLHRVARKLGIDCVQAITGFDFHGG-YCHPVTDGYVVCEEFRDVLLAAWENEQALIEKKEKEKKEKRALGNWKLLVRGLLIRERLKLRYGAKSEAAAPHANAGGGLSSDEEEGTSSQAEAAR--VLAASWPQNRETKEEQKPD-YTKMTRRRRAAEASHLFPFEKL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51612-1", "uniprot_id": "XPC_MOUSE", "id": "P51612-1", "name": "DNA repair protein complementing XP-C cells homolog", "aln": "----------------------------------------------------------------------------------------------------MAPKRTADGR---RRKRGQKTED-------NKVARHEESVADDFEDEKQKPRRKSSFPKVSQGKRKRGCSDPGDPTNG-------------------------------------------AAKKKVAKATAKSKNLKVLKEEALSD-GDDFRDSPADCKKAKKHPKSKVVD------QGTDEDD--SEDDWEEVEELTEPVL--------------------DMGENSATSPSDMPVKAVEIEIETPQQAKERERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLLASGFYRNSICRQPD-LLAIGLSIIPIRFTKVPLQDRDAYYLSNLVKWFIGTFTVN-----ADLSASEQDDLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVTK----------------------------------GRKSSKETSVEGPGGSSELSSNSPESHNKPTTSRRIKEEETLSEGRG---------------------------------------------------------------------KATARGKRGTGTAGSRQRRKPSCSE-----GEEAEQKVQGRPHAR-----------------KRRVAAKVSYKEESESDGAGSGSDFEPSSG----------------------------------EGQHSSDEDCEPGPRKQKRASAPQRTKAGSKSASKTQRGSQCEPSSFPEASSSS-------------------SGCKRGKKVSSGAEEMA-----------------------------------------------------------------------DRKPAGVDQWLEVYCEPQAKWVCVDCVHGVVGQPVACYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLR------PYRSLLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPETAAVLGYCRG-------EAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDHNDLGLYGHWQTEEYQPPIAVD-GKVPRNEFGNVYLFLPSMMPVGCVQMTLPNLNRVARKLGIDCVQAITGFDFHGG-YCHPVTDGYIVCEEFRDVLLAAWENEQAIIEKKEKEKKEKRALGNWKLLVRGLLIRERLKLRYGAKSEAAAPHA-AGGGLSSDEEEGTSSQAEAAR--VLAASWPQNRED-PEQKSE-YTKMTRKRRAAEASHLFPFEKL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01831-1", "uniprot_id": "XPC_HUMAN", "id": "Q01831-1", "name": "DNA repair protein complementing XP-C cells", "aln": "----------------------------------------------------------------------------------------------------MARKRAAGGEPRGRELRSQKSKA-------KSKARREEEEEDAFEDEK--PPKKSLLSKVSQGKRKRGCSHPGGSADG-------------------------------------------PAKKKVAKVTVKSENLKVIKDEALSD-GDDLRDFPSDLKKAHHLKRGATMN------EDSNEEEEESENDWEEVEELSEPVLG-------------------DVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPD-LHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVN-----AELSASEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAK----------------------------------GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTC---------------------------------------------------------------------RPSAKGKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR-----------------ERRVASRVSYKEESGSDEAGSGSDFELSSG----------------------------------EASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSS-------------------SSSKRGKKMCSDGEKAE-----------------------------------------------------------------------KRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLR------PYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRG-------EAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVD-GKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGG-YSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAAR--ILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24595-1", "uniprot_id": "XPC_DROME", "id": "Q24595-1", "name": "DNA repair protein complementing XP-C cells homolog", "aln": "MSDEEEDSVSEGFSASEDEWKPSKDVKGGESSDDDDSDFDELQAEGGAAGSSGRSSAVAGKRGDHKAPSGIKGSSVKKRKPTGQSLRSKLYNKYRPPPKTFPTSPSQQKENTPRASGSKNAKTPNESGARNQHGPADSSSESSVEDYLVNPADLDLHSTFFAGGQKEKSPAPQFDCNAGITNLSDSGSEDNNESSFEDKAGNAFDFRGLLENANSLERTRDALSKRNVTATPPRSQAATMDVNALLALGENQNYQSVEVEEREGNQRKKAGRGAPAAPPTLDEPSRLSKTKSTRIKRHTKTRPVSTVVANAGDTDDSDFEEVADADLSSDQDDGETPNISGDLEIRVGLEGLRPTKEQKTQHELEMALKRRLNRDIKDRQILLHKVSLMCQIARSLKYNRLLSESDSLMQATLKLLPSRNAYPTERGTELKYLQSFVTWFKTSIKLLSPNLYSAQSPATKEAILEALLEQVKRKEARCKQDMIFIFIALARGMGMHCRLIVNLQPMPLRPAASDLIPIKLRPDDKNKSQTVESERESEDEKPKKDKKAGKPAEKESSKSTISKEAEKKNNAKKAEAKPLSKSTTKGSETTKSGTVPKVKKELSLSSKLVEKSKHQKAYTSSKSDTSFDEKPSTSSSSKCLKEEYSELGLSKKLLKPTLSSKLVLKSKNQSSFSSNKSDTSFEENPSTSSSSKSLKEETAKLSSSKLEDKKVASPAETKTKVQSSLLKRVTTQNISESGDSKKPKVAPVDTFSPVAGRTRRATVKPKTEEKPQVVGSPVIPKLMLSKVKQLNAKHSDTENASPANKHLQEQRNTRETRSRSKSPKVLISPSFLKKKSDGADSTSDPQKHQMAPETKARISPNFLSEALPARQLRSRGQKASSLAIPQLDGGDDVPLPKKRPKLEKLKNSQDSDEVFEPAKPVKKAPVLPKSVQNLRKDRRVMSTDDEGGSRLNRKTDASDMWVEVWSDVEEQWICIDLFKGKLHCVDTIRKNATPG---------LAYVFAFQDDQSLKDVTARYCASWSTTVRKARVEKAWLDETIA------PYLGRRTKRDITEDDQLRRIHSDKPLPKSISEFKDHPLYVLERHLLKFQGLYPPDAPTLGFIRG-------EAVYSRDCVHLLHSREIWLKSARVVKLGEQPYKVVK---ARPKWDRLTRTVIKDQ-PLEIFGYWQTQEYEPPTAEN-GIVPRNAYGNVELFKDCMLPKKTVHLRLPGLMRICKKLNIDCANAVVGFDFHQG-ACHPMYDGFIVCEEFREVVTAAWEEDQQVQVLKEQEKYETRVYGNWKKLIKGLLIRERLKKKYNF--------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14736-1", "uniprot_id": "RAD4_YEAST", "id": "P14736-1", "name": "DNA repair protein RAD4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MNEDLPKEYFELIRKALN------------------------------------------------------EKEAEKAPLSRRRRVRRKNQPLPDAKKKFKTGLNELPRESVVTVN----------LDSSDDGVVTVPTDDSVEEIQSSEED------------------YDSEEFEDVTDGNEVAGVEDISVEIKPSSKRNSDARRTSRNVCSNEERKRRKY-------FHMLYLVCLMVHGFIRNEWINSKR-LSRKLSNLVPEKVFELLHPQKDEELP-------------------LRSTRKLLDGLKKCMELWQKHWKITKKYDNVGLYMRTWKEIEMS---------------------------------------------------------------------------ANNKRKFKTLKRSDFLRAVSKGHG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLN--------------------GNNAYKDMVKYP----------------------------------------------------------------------------------IFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPG-CKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVGRPKGE-------AEEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFIQEDDNRKEHLLGALESWNTLLLKLRIRSKLNSTYGKIAEEEPNVTKEQNIADNHDNTETFMGGGFLPGIANHEARPYSEPSEPEDSLDYVSVDKAEESATDDDVGEDYSDFMKELEMSEESD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .*. ... . . :.* .. . : . .: : ::. .. * . ::.:. .. .: . :. .* .: * : *:* :. .: * . * .::* : : : : : : . . : : ::: : : : : . * : . .: .* . :: . .. . . . :: . :.: * **: . . :*: :* .: . : : **.. : . :*** ** : .** *: *. : . : ** : . .: :* :: *:** *.*::.: : : : * . *: : **:: : *:* * ..*::: *. *::* *.: :. ::.. :*: * ** * * :.:* :**: :* *:* : * : .: *.:: . *:..*.*. * :*: .* :*.: :::.: :* : : : .:::: . .*: * * **.:*: *. ", "identical_positions": 78, "similar_positions": 198, "identity": "5.54%" }, { "cls_id": "homologset.agr.SGD:S000000965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z5-1", "uniprot_id": "CHAC2_RAT", "id": "Q641Z5-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDP-------------------------GGSVWGVAYKLPVGKEEEVKTYLDFRE--KGGYRTTTVIFYPKDSTTKPFS--------------------VLLYIGTCDNPNYLGPA-PLEDIAEQIFNAAGPSGRNTEYLFELADSIRKLVPEDADEHLFSLEKLVK--------ERLEGK------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQG1-1", "uniprot_id": "CHAC2_MOUSE", "id": "Q9CQG1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDP-------------------------GGSVWGVAYKLPVGKEEEVKTYLDFRE--KGGYRTTTVIFYPKDSTTKPFS--------------------VLLYIGTCDNPNYLGPA-PLEDIAEQIFNAAGPSGRNTEYLFELADSVRKLVPEDADEHLFSLEKLVK--------ERLEGK------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUX2-1", "uniprot_id": "CHAC2_HUMAN", "id": "Q8WUX2-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDP-------------------------AGCVWGVAYRLPVGKEEEVKAYLDFRE--KGGYRTTTVIFYPKDPTTKPFS--------------------VLLYIGTCDNPDYLGPA-PLEDIAEQIFNAAGPSGRNTEYLFELANSIRNLVPEEADEHLFALEKLVK--------ERLEGKQNLNCI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KMJ1-1", "uniprot_id": "CHAC2_DANRE", "id": "Q4KMJ1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYEDKRVGFVKGFSRRFWQGSTDHRGVPGKPGRVVTLIEDP-------------------------EGCVWGVAYKLPSGQEQEVKEYLDYRE--KGGYGVITVTFHPKDEQQQPMQD-------------------TLLYIGSCDNPNYLGPA-PLETIAQQIVKSVGPSGKNTDYLFELADALRQLVPEDLDDHLFSLERLVK--------QLQEQEDMD---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R3J5-1", "uniprot_id": "CHAC1_MOUSE", "id": "Q8R3J5-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------------MKQESASQSTPPPSLSPAPSSAQPSWGDGDPQ----------------------------ALWIFGYGSLVWKPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLEDR-------------------------EGCTWGVAYQVRGEQVNEALKYLNVREAVLGGYDTKEVTFYPQDTPDQP--------------------LTALAYVATPQNPGYLGPA-PEEVIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLEAIVDAVG--------TLLPCSYLPEQPLALT--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3STU3-1", "uniprot_id": "CHAC1_RAT", "id": "B3STU3-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------------MKQESAAQSTPPPSLSPAP-SAQPSWEDGDPQ----------------------------ALWIFGYGSLVWKPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLEDH-------------------------EGCTWGVAYQVRGEQVSEALKYLNVREAVLGGYDTKEVTFYPQDTPDQP--------------------LTALAYVATPQNPGYLGPA-PEEVIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLEAIVDAVG--------SLLPCSYLSEQPLALI--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUX1-1", "uniprot_id": "CHAC1_HUMAN", "id": "Q9BUX1-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------------MKQESAAPNTPPTSQSPTP-SAQFPRNDGDPQ----------------------------ALWIFGYGSLVWRPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLEDH-------------------------EGCTWGVAYQVQGEQVSKALKYLNVREAVLGGYDTKEVTFYPQDAPDQP--------------------LKALAYVATPQNPGYLGPA-PEEAIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLAAIVDAVG--------TMLPCFCPTEQALALV--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPB6-1", "uniprot_id": "CHAC1_DANRE", "id": "Q5SPB6-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------------MKPQDIVAGKS-------------------------------------------------SLWIFGYGSLVWKPDFKYKRSKVGYIKGYKRRFWHGDNFHRGDDEMPGRVVTLIEED-------------------------DVCTWGVAFEVTGSQMEESLKYLNVREAVRGGYLTRAVDFFPRGTNQPP--------------------VQALVYIATPDNPIYLGPA-STEEIASQIAVCKGNSGHNIEYLLRLAEFMRVSCPDVDDPHLFSIEAALL--------ATIRPILLAA--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCI9-1", "uniprot_id": "Q9VCI9_DROME", "id": "Q9VCI9-1", "name": "glutathione-specific gamma-glutamylcyclotransferase", "aln": "------MAHFSGHRQPATVPSHFKDLFTNGQLGAAEESNNNDQNEQEN-----------RPSNNNNAGPSDPACWVFGYGSLCWHPGFNYTKCITGYIRGYVRRFWQGNVTHRGCEEKPGRVATLVEDK-------------------------EGITWGCAYRITG---STALDYLKQRECTLGGYATIDTKFFPRVASQDTPFS--------------GEAVEVLVYVATPENIYWLGDD-PVEEIAQQIVSCRGPSGHNAEYLLRLALFMHEEIPGVRDDHLFELEQLVL--------EELYRRQIPLSSVMGRNPDRIRRDSHEDIRRPPSFEFTSR--VPDTKLRCLNI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYK7-1", "uniprot_id": "Q9VYK7_DROME", "id": "Q9VYK7-1", "name": "glutathione-specific gamma-glutamylcyclotransferase", "aln": "MLDFLTELRSSGSRADQLPGNIYTEFFANVIEEPREHGCKSADQDFTQGFSMLRTFDTENSNQLEPPAATDADVWIFGYGSLVWKTDFPYIDRRRGFVWGFKRRFYQHSIDHRGIPERPGRVVTLLPGDP-----------------------AQDRVYGVAYRIAASQKGAVLDHLDYRE--KNGYERCSLEFHEYPTDGAEP-------------------IQVIMYVATQANDSYAGDVWQVPCIARQIFSSAGPSGPNREYLFNLAAAMDQLFPGAVDEHLEELVACVKRYIVEDEPQLIRHALLHEISGILEEEQLAEQAHQLEKLLERCQKPGGREWLIYAALQAKNKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32656-1", "uniprot_id": "CHAC_YEAST", "id": "P32656-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase", "aln": "------------MTNDNS------------------------------------------------------GIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVRE--QNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVGPE-TVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIMKERGRITDHYLTAL----------LETVNKYR--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::***** :: * . : .: ***:: . *** ****.**: . * .: : :*. ** .** .. . *:.: * : * * * . * ** * :** .* : :: ", "identical_positions": 37, "similar_positions": 33, "identity": "10.42%" }, { "cls_id": "homologset.agr.SGD:S000000966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40201-1", "uniprot_id": "CHD1_MOUSE", "id": "P40201-1", "name": "ATP-dependent chromatin remodeler CHD1", "aln": "------MNGHSDEESVRNGSGESSQSGDDCGSASGSGS-GSSSGSSSDGSSSQSGSS----------------------------------DSDSGSDS-GSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAMLRKQPQQAQQQ-RPASSNSGSEEDSSSSEDSDDSSSGAKRKKHNDEDWQMSGSGSPSQSGSDSESEEERDKSSCDGTESDYEPKNKVRSRKPQNRSKSKNGKKILGQKKRQIDSSEDEDDE-D---YDNDKRSSRRQATVNVSYKED-EEMKTDSDDLLEVCGED-------VPQPEDEEFETIERVMDCRVGRK-------GATGATTTIYAVEADG-DPNAGFERNKE---PGDIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKK---DQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKS---------------AAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQ----TKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYAS-LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQ-------EALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSA--PSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGP---LSVGDELLSQFKVANFSNMDE---------DDIELEPERNSKNWEEIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQIS-FNGSEGRRSR--SRRYSGSDSDS------ISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKS-----ETDLRRLGELVHNGCVKALKDSSSGTER---AGGRLGKVKG-----PTFRISGVQ-VNAKLVIAHEDELIPLHKSIPSDPEE---RKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSR--DLAKREAQRLCGAGGSKRRKTRAKKSKAMKSIKVKEEIKSDS---SPLPSEKSDEDDDKLNDS---------------------------------------------------------KPESKDRSK--------------------------KSVVSDAPVHITASGEPVPIAE-ESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKR--QESQQNSDQNSNVATTHVIRNPDMERLKENTNHDDSS-------RDSYSSDR--------HLS-QYHDHHKDRHQGDSYKKS-DSRKRPYSS--FSN-----GKDHR--EWDHYRQ-----DSRYYSDR------------EKHRKLDDHRS-REHRPSLE--------GGLKDRCHSDHRSHSDHR---MHS----------------------DHRS-SSEHTHHKSSRDYRYLSDWQ-------------LDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSS---RKT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5T4-1", "uniprot_id": "A0A0G2K5T4_RAT", "id": "A0A0G2K5T4-1", "name": "", "aln": "------MRAVGKVGRTVLISSPHCQSEDDSGSASGSGS-GSSSGSSSDGSSSQSGSS----------------------------------DSDSGSDS-GSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAMLRKQTQQPQQQ-RPASSNSGSEEDSSSSEDSDASSSDVKRKKHNDEDWQMSGSGSPSQSGSDSESEDERDKSSCDGTESDYEPKNKVKSRKPQNRSKSKSGKKILGQKKRQIDSSEDEDDE-D---YDNDKRSSRRQATVNVSYKED-EEMKTDSDDLLEVCGED-------VPQTEDEEFETIERFMDCRVGRK-------GATGATTTIYAIEADG-DPNAGFEKSKE---PGDVQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKK---DQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKS---------------AAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQ----TKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYAS-LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQ-------EALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRRQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSA--PSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGP---LTVGDELLSQFKVANFSNMDE---------DDIELEPERNSKNWEDIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQIS-FNGSEGRRSR--SRRYSGSDSDS------ISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKS-----ETDLRRLGELVHNGCVKALKDSSSGTER---AGGRLGKVKG-----PTFRISGVQ-VNAKLVIAHEDELIPLHKSIPSDPEE---RKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSR--DLAKKEAQRLSGAGGSKRRKTRAKKNKAMKSIKVKEEIKSDS---SPLPSERSEEEDDNVNDS---------------------------------------------------------KPESKDRSK--------------------------KSVVSDAPVHITASGEPVPIAE-ESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKR--QESQQNSDQNSNVPTTHVIRNPDMERLKENTNHDDSS-------RDGYSSDR--------HLS-QCHDHHKDRHQGDSYKKS-DSRKRPYSS--FSN-----GKDHR--EWDHYRQ-----DSRYYSDR------------EKHRKLDDHRS-REHRPSVE--------GSLKDRCHSDHRSHSDHR---MHS----------------------DHRS-STEHTHHKSSRDYRYLSDWQ-------------LDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSS---RKT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14646-1", "uniprot_id": "CHD1_HUMAN", "id": "O14646-1", "name": "ATP-dependent chromatin remodeler CHD1", "aln": "------MNGHSDEESVRNSSGESSQSDDDSGSASGSGS-GSSSGSSSDGSSSQSGSS----------------------------------DSDSGSES-GSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEED---YDNDKRSSRRQATVNVSYKED-EEMKTDSDDLLEVCGED-------VPQPEEEEFETIERFMDCRIGRK-------GATGATTTIYAVEADG-DPNAGFEKNKE---PGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKK---DQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKS---------------AAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQ----TKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYAS-LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQ-------EALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSA--PSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGP---LTVGDELLSQFKVANFSNMDE---------DDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQIS-FNGSEGRRSR--SRRYSGSDSDS------ISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKS-----ETDLRRLGELVHNGCIKALKDSSSGTER---TGGRLGKVKG-----PTFRISGVQ-VNAKLVISHEEELIPLHKSIPSDPEE---RKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSR--DLAKKEA--LSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDS---SPLPSEKSDEDDDKLSES---------------------------------------------------------KSDGRERSK--------------------------KSSVSDAPVHITASGEPVPISE-ESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKR--QESQQNSDQNSNLN-PHVIRNPDVERLKENTNHDDSS-------RDSYSSDR--------HLT-QYHDHHKDRHQGDSYKKS-DSRKRPYSS--FSN-----GKDHR--DWDHYKQ-----DSRYYSDR------------EKHRKLDDHRS-RDHRSNLE--------GSLKDRSHSDHRSHSDHR---LHS----------------------DHRS-SSEYTHHKSSRDYRYHSDWQ-------------MDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSS---RKT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B604-1", "uniprot_id": "A0A8M3B604_DANRE", "id": "A0A8M3B604-1", "name": "", "aln": "------MDGRSEDESVSNSSGESSNSDDESGSGSGSGS-GSSS-SSSSSSSSQSGSS----------------------------------DSGSGSDS-GSQSDSDSEKSKEKNDQDN--KIDGAAFWNSNPSILTVQRTAMLRKQQIQQQQLQQQSSSNTGSDEDSSSSDESDDDSKSRSKGSGSD-----SDSGSGSGSGSSDSSAEEEANS--DESVSDYEPSHKVKSRKPSNKANARNGRNNKAPKKKPSHSSSDDEDD-----YKKALAGPRRQATVNVSYKED-EELKTDSDDLVEVCGED-------VPPPEEDEFETLERVMEMRIGRK-------GVTGAVTTVYAVEADG-DPNANFDPNRQ---PGEVQYLIKWKNWSHIHNTWETEETLKQQNVKGMKKLDNFKKK---EQEKKKWLKAASPEDVEYFNCQQELMDDLHSQYQLVERIIGHSNQKS---------------AAGYPDYLCKWQGLPYSECSWEDGALISKKFQKCIDEYMSRNQCKTIPSRDCKVLKQRPRFVPMKKQPHYIGG-EGLELRDYQLDGLNWMAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQLWAPLMNVVVYLGDINSRNMIRTHEWMHPQ----TKRLKLNILLTTYEILLKDKSFLGNVSWAFIGVDEAHRLKNDDSLLYKTMIEFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFHSWEMFEEEHGKGRDSGYTS-LHKELEPFLLRRVKKDVEKSLPAKVEQILRVEMSAVQKQYYKWILTRNYKALSKGTKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNRQ-------EGLQHLVRSSGKLILLDKLLVRLKERGHRVLIFSQMVRMLDILAEYLKYRQFLFQRLDGSIKGEMRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEEIIERAKKKMVLDHLVIQRMDTTGKTVLHTGAA--PSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENDPGP---STVGEELLSQFKVANFSMMED---------EEIDMDTERNDRNWDDIIPEDHRRRLEEEERQKELAEIYLLPRMRKCAKQQMNFNGNEGRRSR--NRRYSASDSDS------VSDRKRPKKRGRPRTIPRENIKGFTDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKS-----EHDLRRLAETVHNGCLRTLKENPCGPERT--SGGRRGKVKG-----PTFRISGVQ-VNAKLVISHEEELAPLHKAIPADPEE---RKRYIIPCHSKAAHFDIEWGKEDDSSLLIGIYEYGYGSWEMIKMDPDLNLTHKLLPDDPDKKPQAKQLQTRADYLIKLLSK--DLAKKEAQKQAGTAKSRNRKPRGKKNKAVK-PKMEDVTNSLS---SAPPSDKSSDEEDEKDEEDKETPPPVKLPNRRARVPERTVMEEEDDSDEDELEDAAPVEKDTPEKVVKKEVKKEKKEEGRDSKEREVKEKEIKPEPLQREDDSPAEAVDIKAEKADTPVHTPTGGDAIPLSE-ESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLREYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKR--QENAQAAEQNTSTVNTQSFKHADVERLKE-SQQDESS-------RDSYSSDR--------HHSSRYHEHSKEHHASDSYRKSSDSRKRPYSS--FSN-----GKDHRERERDQYRERGERPDSRYYSE-------------SKHRKLDEHRSSREHRS----------------ESNSKDRTHSEHR---FHS----------------------EHRSGSSDYSHHKSSRDYRYHSDWQ-------------MEHRS-------PRDQRSPIGHRSPFEYSSDHKSTPEQVWSG---RKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PZM4-1", "uniprot_id": "CHD2_MOUSE", "id": "E9PZM4-1", "name": "ATP-dependent chromatin remodeler CHD2", "aln": "---MMRNKDKSQEEDSSLHSNASSRSASEEVS--GSDS-GSQSESEQGSEPGSGHGS----------------------------------ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVK----KMWEEYPDVYGVRRSNRSRQEPSRFNVKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSE---DEQ---EQGTSAESEAEQKKGKARRPVPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDE-----APKRQTRRRAAKNVSYKED-DDFETDSDDLIEMTGEG-------GDE-QQDNSETIEKVLDSRLGKK-------GATGASTTVYAVEANG-DPSDDFDTERE---EGEVQYLIKWKGWSYIHSTWESEDSLQQQKVKGLKKLENFKKK---EDEVKQWLGKVSPEDVEYFSCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGG-ESLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQ----TKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQS-LHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKAPEDSERESGQ-------EVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSG--RSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVS----TSATDELLSQFKVANFATME----------DEEELE-ERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDD----SDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKS-----VADLKRLGELIHNSCVSAMQEYEEQLKESTSEGKGPGKRRG-----PTIKISGVQ-VNVKSIIQHEEEFEMLHKSIPVDPEE---KKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRK--GLEKKGTVASGEEAKLKKRKPRVKKENKAPRLKDEHGLEPASPRHSDNPSEEGEVKDDGLEKSPTKK---------------------------------KQKKKENKENKEKPVSSRKDREGDKERKKSKDKKEKVKGGDGKSSS---------KSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLSVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS-QEEEEQKKKDDSLGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASH--GPQMHGHPRDNYSHPNKRHFSNADRGDWQRERKFNYGG--GNS-APWGGDRHHQYEQHWYKDHHYG-DRR-HMDAHR-SGSYRPNNMSRKRPYEQYNSDRDHRGHRD--------YYDRHHHDSKRRRSDDFRPQNYHQ---------------QDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPSLHTALSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNV---RKT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJY0-1", "uniprot_id": "A0A096MJY0_RAT", "id": "A0A096MJY0-1", "name": "", "aln": "---MMRNKDKSQEEDSSLHSNASSHSASEEAS--ASDS-GSQSESEQGSDPGSGHGS----------------------------------ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVK----KMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSE---DDQ---EQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDE-----APKRQTRRRAAKNVSYKED-DDFETDSDDLIEMTGEG-------VDE-QQDNSETIEKVLDSRLGKKGVDLNPFAATGASTTVYAVEANG-DPSGDFDTERE---EGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKK---EDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGG-ENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQ----TKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQS-LHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQ-------EVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSG--RSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVS----TSATDELLSQFKVANFATME----------DEEELE-ERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDD----SDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKS-----VADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRG-----PTIKISGVQ-VNVKSIIQHEEEFEMLHKSIPVDPEE---KKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRK--GLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKK---------------------------------KQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSS---------KSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS-QEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASH--GPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGG--GNN-APWGGDRHHQYEQHWYKDHHYG-DRR-HMDAHR-SGSYRPNNMSRKRPYEQYNSDRDHRGHRD--------YYDRHHHDSKRRRSDDFRPQNYHQ---------------QDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNV---RKT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14647-1", "uniprot_id": "CHD2_HUMAN", "id": "O14647-1", "name": "ATP-dependent chromatin remodeler CHD2", "aln": "---MMRNKDKSQEEDSSLHSNASSHSASEEAS--GSDS-GSQSESEQGSDPGSGHGS----------------------------------ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVK----KMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSE---DEQ---EQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDE-----APKRQTRRRAAKNVSYKED-DDFETDSDDLIEMTGEG-------VDE-QQDNSETIEKVLDSRLGKK-------GATGASTTVYAIEANG-DPSGDFDTEKD---EGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKK---EDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGG-ENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQ----TKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQS-LHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQ-------EILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSG--RSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVS----TSATDELLSQFKVANFATME----------DEEELE-ERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETED----SDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKS-----VADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRG-----PTIKISGVQ-VNVKSIIQHEEEFEMLHKSIPVDPEE---KKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRK--GLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKK---------------------------------KQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSS---------KSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS-QEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASH--GPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGG--GNNNPPWGSDRHHQYEQHWYKDHHYG-DRR-HMDAHR-SGSYRPNNMSRKRPYDQYSSDRDHRGHRD--------YYDRHHHDSKRRRSDEFRPQNYHQ---------------QDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNV---RKT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQC3-1", "uniprot_id": "A0A8M9PQC3_DANRE", "id": "A0A8M9PQC3-1", "name": "", "aln": "---MMKNKSKKQEDEGSTQSNASSNSASEESNRSGSES-GSQSESEQGSEKAQSRHS----------------------------------ESNSTSDS-ESHSESGSESNGSKSHQSSAQVKDKPVRKKDNLADVKKVHKKMWEEHPDVYGVRRSSRSRQEPARLNIGAEGSSDSEGESSKRKSSRQKKKENTWKDDDSN---DEEDVEEETSSSESEQEEKKVRSRRLPARRPQTKSSASKQSQKGR-KQRKQESSDEDDDDDDDDEEDTPKRQTRRRAATKVSYKEDQNDFETDSDDLIEMAEGA-------EEQ-QDDDSETIEKVVDTRTGKK-------GATGASTTLYAIEENG-DPGADFDPEKE---EGETQFLIKWKGWSYIHNTWESVDSLTQQKVKGMKKLENFKKK---NEELNAWLKKASPEDLEYYNCQQELTNDLSKQFQIIERVIATRTGKS-QATSDTPSHK---SSSGEPEYLCKWMGLPYAECTWEDSALIKKKFQACIDSFHNRNSSKTVPSKDCKVLKQRPRFVPLKKQPSYIGD-ENLELRDYQLDGVNWLAHSWCRCNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFIVVVPLSTLTSWQREFDTWAPDMNVVVYLGDVTSRKTIRDYEWINPQ----TKRIKFNALLTTYEILLKDKGVLGNINWAFLGVDEAHRLKNDDSLLYKTLIDFRSNHRLLITGTPLQNSLKELWSLLHFLMSDKFESWEDFEDEHGKGRDNGYQS-LHKVLEPFLLRRVKKDVEKSLPAKVEQILRVDMSAQQKQFYKWILTRNFKALSKGTRGSSSGFLNIVMELKKCCNHAFLIKQPEDGENDAPQ-------EHLQSLVRGGGKLVLLDKLLTRLKDRGNRVLIFSQMVRMLDILADYLSMKRYQFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEDIIERAKKKMVLDHLVIQRMDTTGRTVLDNSSA--NSNSNPFNKEELSAILKFGAEDLFKEAEGEESEPQEMDIDEILRLAETRESDQG----SSATDELLSQFKVANFTMDE----------STPDLD-EKPGRDWDEIIPEEQRRKVEEEQKQKEMEDIYMLPRSRSSNKKAQANDSDSDVGSK-LKHRSSGSDSETDD----SEDDKRPKRRGRPR-ARKNNVEGFTDAEIRRFIKAYKKFGAPLERLEAIARDSELVEKS-----IADLKRLGELVHNSCVTAVQEHEEHLKENPVEAKGPGKRRG-----INIKISGVQ-VNAKSIIQHEEEFEPLHKAVPSNPAE---RNKFQLTCRVKTPHFDVDWDIHDDTQLLLGIYEHGYGNWDLIKTDPDLKLSEKILLDDPEKKPQGKQLQMRTDYLLKMLKK--DLESQDAIKAGDEPKIKKRKPRMKK--KAP--SNELVNEIASPRLSDNPSEEGEVKDDGAEKTPTKK---------------------------------KQKK-DNKENKEKTGTPKKEKEGDKDKKRSKPKKEK-----AKPAG---------KGKKAQGPVHITQGSEPIPIGE-EDDELDQETFSICKERMRPVKKALKQLDKPDEGLSVQDQLQHTRTCLLKIGDRITECLKSYSDPEHIKIWRRNLWIFVSKFTEFGAQKLHRLYKKAQKKRS-QEGEKEHKKKDDPIKKKPFRPEPSGSSRDSTGAQPTT-------KPHPPVSHQSGPPHPPHHREQYNQHNKRHFPNDDRGDWQRDRKYGYPG--NSN-QPWQGDRHHPYEPHRYKDHHYS-DRRPHGDYRS-SGGYRNSGSPRKRPYDQYGNDRDHRGHRD--------YYDRHP-DPKRRRSDEYRSPNYHQGGGGGGGGGGGGGHPQDFRRMPDHRGPPGNHGPMGPDHYRPFHPDKP-----------PPLIDPRSPQSQKSPLEPISPG-----MDRSAEQKSATDFNWNN---RKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KU24-1", "uniprot_id": "CHD1_DROME", "id": "Q7KU24-1", "name": "ATP-dependent chromatin remodeler Chd1", "aln": "MSQALNESANSIGSDEQDDTREEANGTDHSGSGSGSGSSGSDSDSDSSSGNSSDGRSSPEPEDKSLSVAGFPPTAAAAQADSKTNGFTDDQEDSSSDGSSGSDSDSDAEGPSDQRNQSINNANTSSSLPKPEQNEEEDNETEAGQQQP-ASDASADESSDSSANVSPTSSSSSSEEEEEDYRPKRTRQARKPPTAAEKSKKAPAPKNKKKTWDSDESDESEDSDDEVSTAQKRKPAATTSRSKLAQQQQRRRVKPFSSEDSDDD------DASKRCATRRKGAAVSYKEASEDEATDSEDLLEFEYDESQAATTAATAEEEEKCETIERILAQRAGKR-------GCTGNQTTIYAIEENGFDPHAGFDEKQTPDAETEAQFLIKWKGWSYIHNTWESEATLRDMKAKGMKKLDNFIKK---EKEQAYWRRYAGPEDIDYFECQLELQHELLKSYNNVDRIIAKGSKPD----------------DGTEEYLCKWQSLPYAESTWEDAALVLRKWQRCAEQFNDRESSKCTPSRHCRVIKYRPKFSRIKNQPEFLSS--GLTLRDYQMDGLNWLLHSWCKENSVILADEMGLGKTIQTICFLYSLFKIHHLYGPFLCVVPLSTMTAWQREFDLWAPDMNVVTYLGDIKSRELIQQYEWQFES----SKRLKFNCILTTYEIVLKDKQFLGTLQWAALLVDEAHRLKNDDSLLYKSLKEFDTNHRLLITGTPLQNSLKELWALLHFIMPDKFDTWENFEVQHGNAEDKGYTR-LHQQLEPYILRRVKKDVEKSLPAKVEQILRVEMTSLQKQYYKWILTKNFDALRKGKRGSTSTFLNIVIELKKCCNHAALIRPSEFELMGLQQD------EALQTLLKGSGKLVLLDKLLCRLKETGHRVLIFSQMVRMLDVLADYLQKRHFPFQRLDGSIKGEMRRQALDHFNAEGSQDFCFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQVNIYRLVTARSVEEQIVERAKQKMVLDHLVIQRMDTTGRTVLDKSGNGHSSNSNPFNKDDLSAILKFGAEELFKD-EQEHDDDLVCDIDEILRRAETRNEDPE-----MPADDLLSAFKVASIAAFEEEPSDSVSKQDQNAAGEEDDSKDWDDIIPEGFRKAIDDQERAKEMEDLYLPPRRKTAANQNEGKRGAGKGGKGKQQADDSGGDSDYELGSDGSGDDGRPRKRGRPT--MKEKITGFTDAELRRFIRSYKKFPAPLHRMEAIACDAELQEKP-----LAELKRLGEMLHDRCVQFLHEHKEEESKTAATDETPGAKQRRARATFSVKLGGVS-FNAKKLLACEQELQPLNEIMPSMPEE---RQQWSFNIKTRAPVFDVDWGIEEDTKLLCGIYQYGIGSWEQMKLDPTLKLTDKILLNDT-RKPQAKQLQTRAEYLLKIIKKNVELTKGGQRRQRRPRASRANDAKAASQSASSTIDAKPHDGEDAAGDARTVAESSNSQVDPSTASPHNAP-----------------------------------------ATEQHGDPAKKAKKSKARSKKTS----------------------ASDNNGNKPMHFTANNEPRALEV--LGDLDPSIFNECKEKMRPVKKALKALDQPDVSLSDQDQLQHTRDCLLQIGKQIDVCLNPYAETE-KKEWRSNLWYFVSKFTELDAKRLFKIYKHALKQKAGGDGEAKGKDKGSSGSPAKSKPNGVTTEEKEKERDRSGGKKKKKDKDKERSGQARYPETGIPTSGRYADPPLKRKRDENDADASSGLAGAPGGGIGDNLKSMSFKRLNMDRHEDRKKHHRGPDYYGGSGPPMGSGSYEGGSNSRRQGPTSPSTPRTGRGGYDPPPAPSGYTPEMERWQSRDRYSQDYKRDRYDG-------YGRSGGGQGSYHRERDRRPEKRRYPSGLPPHPYSSHYLPP--------------NYYGLPNGAVPGLPPPSSVYRSDPRGYPVMPRDYPADYRRSDYERRTQT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32657-1", "uniprot_id": "CHD1_YEAST", "id": "P32657-1", "name": "ATP-dependent chromatin remodeler CHD1", "aln": "------MAAKDISTEVLQNPELYGLRRSHRAAAHQQNYFNDSDDEDDEDNIKQSRRK------------------------------------------------------------------------------------RMTTIEDDEDEFEDEEGEEDSGEDEDEEDFEEDDDYYGSPIKQ-------------------------------NRSKPKSRTKSKSKSKPKSQSEKQSTVKIPTRFSNRQNKTVNYNIDYSDDD----------------LLESEDDYGSEEALSEENVHEASANP-----------QPEDFHGIDIVINHRLKTS-------LEEGKVLEKTVPDLNN--------------CKENYEFLIKWTDESHLHNTWETYESIG--QVRGLKRLDNYCKQFIIEDQQVRLDPYVTAEDIEIMDMERERRLDEFEEFHVPERIIDSQRASLEDG-------------TSQLQYLVKWRRLNYDEATWENATDIVKLAPEQVKHFQNRENSKILPQYSSNYTSQRPRFEKLSVQPPFIKG---GELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYLFDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAIISLGVTDGNKYTKKNEP---------NAGELSAILKFGAGNMFTATDNQK-KLEDLNLDDVLNHAEDHVTTPDLGESHLGGEEFLKQFEVTDYKADID-------WDDIIPEEELKKLQDEEQKRKDEEYVKEQLEMMNRRDNALKKIKNSVNGDGTAANSDSDDDSTSRSSRRRARANDMDSIG-----ESEVRALYKAILKFGNLKEILDELIADGTLPVKSFEKYGETYDEMMEAAKDCVHEEEKNRKEILEKLEKHATAYRAKLKSGEIKAENQPKDNPLTRLSLKKREKK---AVLFNFKGVKSLNAESLLSRVEDLKYLKNLINSNYKDDPLKFSLGNNTPKPVQNWSSNWTKEEDEKLLIGVFKYGYGSWTQIRDDPFLGITDKIFLNEVHNPVAKKSASSSDTTPTPSKKG--KGITGSSKKVPGAIHLGRRVDYLLSFLRGGLNTKSPSADIGSKKLPTGPSKKRQRKPAN-------------------------------------------------------------------------------------------------HSKSMTPEITSSEPANGPPSKRMKALPKGPAALINNTRLSPNSPTPPLKSKVSRDNGTR---QSSNPSSGSAHEKEYDSMDEEDCRHTMSAIRTSLKRLRRGGKSLDRKEWAKILKTELTTIG--NHIESQKGSSRKASPEKYRKHLWSYSANFWPADVKS----------------------TKLMAMYDKITESQKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .... ... . .. . . . .. . . : . :: . . . .: * .: .: ..::: * : :. . :: .: * * . : :. : ::****.. *::*.***: :: :.:*:*:*:*: *: :.: . .**:: . : * : ..:: :*:* . :* ** * * *.:**: : : : . : .*:..* * .. . **:* :. ** :: . ***:*: *:**: . *.: :. ***********:**:.*: *: :: **.: ******:.:* :: **. :* : *:*: **. *: :*: .* :*:* ::**** :***: ** :.* : ********* :* **::: .* :*:*********.:*** :*::*:*. :* : :: :: . .: * **: ::*::***:*********:*.*:***:::: *.::** ***:*:.** * :*. :***: ****..** *: .: : * *: ..**::***:** **:. *:*************:*.:** : ******:: . *: ::****: .*:** ************** :****:********* **** *********::* :****: :***:::***::**:*:: :*. * *.. ... * :*:******* ::*. : :. . ::*::*. ** : :::*. *:*:. . :: :: : : : :. : . . . . ..: : . :. :. . : . *: :::::*: . ..: * *. :: .*.: . : . . . ..: **. .*.: :: ::: *:: : : : . :. :* .:* ** *::::* *.* :: ** * ::.*:: : . *. . . . . . : . :. . . . * . . . : :: * . : .: . . . : : :. . . .: .: . . * .* : ..:. :. :: * . : . . : . : . : ", "identical_positions": 308, "similar_positions": 412, "identity": "15.14%" }, { "cls_id": "homologset.agr.SGD:S000000967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A5N3-1", "uniprot_id": "PAP1L_MOUSE", "id": "A2A5N3-1", "name": "Polyadenylate-binding protein 1-like", "aln": "--------------------MDTGGHG-------CSLSSLYVGDLHPDVTESMLYEMFSPIGNILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHG-SRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARA-LGFTNIYVKNLHANVDEQRLQDLFSQFGNMQSVKVMRDSNGQSRGFGFVNFEKHEEAQKAVDHMNGKEVS-GQLLYVGRAQKRAERQSELKRRFEQMKQE----------RQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVITSAKVMT-ESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRP------SHPVLS-SFQQP--TSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPLSTTQHP---CIHLRGASQVSSQVP------HTQRVVNIGTQTTGPGG--------------------------------EGSSIPGQLLVPHRG------------TSAVHSAHGVQESAVYVPGH--QPLTVSMLAAAPLHEQKQMIGERLYSLIHDACAP--LTGKITGMLLELDNLELLLLLESPESLHAKIEEAVAVLQVHREMESTD--RN--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAS7-1", "uniprot_id": "D3ZAS7_RAT", "id": "D3ZAS7-1", "name": "Polyadenylate-binding protein", "aln": "--------------------MDTRGHG-------CSLSSLYVGDLHPDVTEAMLYEMFSPIGTILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMIKGQPIRIMWSHRDPGLRRSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHG-SRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARA-LGFTNIYVKNLRVDMDEQGLQDLFSQFGKTQSVKVMRDSNGQSRGFGFINFEKHEEAQKAVDHMNGKEVS-GQLLYVGRAQKRAERQNELKRRFEQMKQE----------RQNRYQGVNLYVKNLDDSINDDRLKEVFSTYGVITSAKVMT-ESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRL------SRSVLS-SFQQP--TSYLLPAVHQSTTQTMYYSSASIAPMQPDPRWTAQPHGPSSTCPPAASVVQPLSTAPHP---CIHLSSASQASSQVP------HTQRVVNIGTQTTGPGG--------------------------------EGSCIPGQPLLAHRG------------SSAVHSAHGVQESTVYVPGH--QPLTVSMLDAAPLHEQKQMIGERLYSLIHDACAP--LTGKITGMLLEMDNLELLLLLESPESLHAKIEEAVAVLKAHRAMESADSYRN--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VXU2-1", "uniprot_id": "PAP1L_HUMAN", "id": "Q4VXU2-1", "name": "Polyadenylate-binding protein 1-like", "aln": "--------------------MNASGSG-------YPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARA-LEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVS-GRLLYAGRAQKRVERQNELKRRFEQMKQD----------RLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMT-EGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLG-SFQQP--SSYFLPAMPQPPAQAAYYGCGPVTPTQPAPRWTSQPPRPSSAYPPGASMVRPPVVPRRP---PAHISSVRQASTQVPRTVP--HTQRVANIGTQTTGPSG--------------------------------VGCCTPGRPLLPCKC------------SSAAHSTYRVQEPAVHIPGQ--EPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQ--LAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAMEQPKAYMH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZX4-1", "uniprot_id": "A0AB32TZX4_DANRE", "id": "A0AB32TZX4-1", "name": "Polyadenylate-binding protein", "aln": "--------------------MNSGGPA-------YPLASLYVGDLHADVTEAMLYQKFSPAGQIMSIRVCRDVITRRSLGYAYINFQQPADAECALDTMNYEVIKGRPIRIMWSQRDPGLRKSGVGNIFIKNMDESIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAANRAIETMNGMLLNDRKVFVGHFKSRKEREAEMGAKA-VEFTNVYIKNFGEDIDSEKLKNIFTEFGKTLSVCVMTDERGRSRGFGFVNFVNHGDARRAVTEMNGKELN-GRVLYVGRAQKRLERQGELKRKFEQIKQE----------RIQRYQGVNLYVKNLDDSIDDEKLRKEFAPYGTITSAKVMT-DGGHSRGFGFVCFSSPEEATKAVTEMNGRIVSTKPLYVALAQRKEERKAILTNQYIQRLASIRAIPGPAIPTTYQQG--SGYYMTSVPQVRS---FYN--AVPNLRPAPRWASQAPRTQGPFP--AQFVR-QAVPRRP---STTISTVRQASTQVPHIN---NTQRMANIGTQTAGGRA--------------------------------AGTAVRGVSQYKYSAGVRNVQQVINAPAPVVHQVVQNTEPAVHMKGQ--EPLTASMLAAAPLKEQKQLLGERLYPLIQILHPA--LAGKITGMLLEIDNSELLHMLESPESLHAKVEEAVAVLQAHQAKEMSAK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29341-1", "uniprot_id": "PABP1_MOUSE", "id": "P29341-1", "name": "Polyadenylate-binding protein 1", "aln": "--------------------MNPSAPS-------YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARA-KEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRPAAPRP-------PFSTMRPASSQVPRVM---STQRVANTSTQTMGPRP--------------------------AAAAAAATPAVRTVPQYKYAAGVRNPQQ-----HLNAQPQVTMQQPAVHVQGQ--EPLTASMLASAPPQEQKQMLGERLFPLIQAMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPH8-1", "uniprot_id": "PABP1_RAT", "id": "Q9EPH8-1", "name": "Polyadenylate-binding protein 1", "aln": "--------------------MNPSAPS-------YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARA-KEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRPAAPRP-------PFSTMRPASSQVPRVM---STQRVANTSTQTMGPRP--------------------------AAAATAATPAVRTVPQYKYAAGVRNPQQ-----HLNAQPQVTMQQPAVHVQGQ--EPLTASMLASAPPQEQKQMLGERLFPLIQAMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11940-1", "uniprot_id": "PABP1_HUMAN", "id": "P11940-1", "name": "Polyadenylate-binding protein 1", "aln": "--------------------MNPSAPS-------YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARA-KEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRPAAPRP-------PFSTMRPASSQVPRVM---STQRVANTSTQTMGPRP--------------------------AAAAAAATPAVRTVPQYKYAAGVRNPQQ-----HLNAQPQVTMQQPAVHVQGQ--EPLTASMLASAPPQEQKQMLGERLFPLIQAMHPT--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H361-1", "uniprot_id": "PABP3_HUMAN", "id": "Q9H361-1", "name": "Polyadenylate-binding protein 3", "aln": "--------------------MNPSTPS-------YPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARA-KEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRTFEQMKQD----------RITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN------QRAP-PSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKP-SAIRPGAPRV-------PFSTMRPASSQVPRVM---STQRVANTSTQTVGPRPA-------------------------AAAAAAATPAVRTVPRYKYAAGVRNPQQ-----HRNAQPQVTMQQLAVHVQGQ--ETLTASRLASAPPQKQKQMLGERLFPLIQAMHPT--LAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QB54-1", "uniprot_id": "PABPA_DANRE", "id": "F1QB54-1", "name": "Polyadenylate-binding protein 1A", "aln": "--------------------MNPSAPS-------YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMMTRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETHEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEMGARA-KEFTNVYIKNFGEDMDDEKLKEIFCKYGPALSIRVMTDDSGKSKGFGFVSFERHEDAQRAVDEMNGKEMN-GKQVYVGRAQKKGERQTELKRKFEQMKQD----------RMTRYQGVNLYVKNLDDGLDDERLRKEFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTSQYMQRMASVRAVPNPVLNPYQPAP-PSGYFMAAIPQAQNRAAYYPTSQLAQLRPSPRWATQGVRPQHFQNMPNAAVRPSAPRPQ------TFNPVRPAS-QVPRMM---TSQRMG---SQAMGPRPA-------------------------AAGAATGPAQVRGVPQYKYAPGVRNPQQ-----HMPTQPQVPMQQPAVHVQGQ--EPLTASMLAAAPPQEQKQMLGERLFPLIQNMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKSVPSP-AVPAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B5DF80-1", "uniprot_id": "B5DF80_RAT", "id": "B5DF80-1", "name": "Polyadenylate-binding protein", "aln": "--------------------MNPSDPS-------YSLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVYRDRTTRRSLGYASVNFQQLEDAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDRSIDSKTLYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEEAERAIEKMNGMFLNDRKVFVGRFKSRRDRQAELGARA-KEFTNVYIKNLGEDMDDERLQDLFSRFGPALSVKVMTDESGKSKGFGFVSFERHEDARKAVDEMNGKDLN-GKQIYVGRAQKKVERQTELKHKFGQMKQDKPKIEQVPQDRSVRCQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVTM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLSNQYMQRMASTSAVPNPGINPFQPAQGLSGYFMTATAPTQNRGTYYAPNQTTQQGPSARGSAQGTRAHPFQNMS-SAIHPSNTMP-------SFSTSGPTSSQAVR-------HRTASTSTQMMGPHP--------------------------AAASTAAAPAARTVTQYKYTAGVRNPPQ-----HLNTQPQVTTQRSAVSAQGK--ESLTVSMLASAPPQAQKQMLGEWLFSLIQAMHPA--LAGKITGMLLEIDNLELRHMLESPECLHTKVDEAIAVLQAHQAKETSQKAVSSVAGVPTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A233-1", "uniprot_id": "D4A233_RAT", "id": "D4A233-1", "name": "", "aln": "--------------------MNSSDPG-------CPMASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVCDENG-SKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFVGQFKSRKEREAELGTRT-KEFTNVYIKNFGDRMDDKTLNGLFGRFGQVLSVKVMTDEGGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKHIYVGPAQKKVDRHIELKRKFEQVTQD----------RGIRYQGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMT-EGGRSKGFGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQRKEERQAHLTNQYIQRMASVRSGPNSLINAYQPAP--SGYSVAAVPQTQNCAPCCP-SQIVQPSPSTRWTAQGARPHPFPNVS-GASHPAAPKS-------SFTTVRPSSSHVPQVM---AAQRITNTSAQTTGQRP--------------------------ALASSPATTPVRSIPQYKYATGVRNSQQ-----HLNAQ---LVQQPSVCIQGQ--EPWTASTLGTAP-QEQKQMLGERLFPLIQAMHPT--LAG--TSQLLK-ECSEYDHQI---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3V9N0-1", "uniprot_id": "G3V9N0_RAT", "id": "G3V9N0-1", "name": "Polyadenylate-binding protein", "aln": "--------------------MNAAASS-------YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAANKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA-KEFTNVYIKNFGEEVDDENLRELFSQFGKTLSVKVMRDCSGKSKGFGFVSYEKHEDANKAVEEMNGKEMS-GKSIFVGRAQKKVERQAELKRKFEQLKQE----------RISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQ-QGGRPQGFQGMP-SALRQSGPRP-------ALRHLAPTGNAPASRGLPTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVPNLAPRATVAAAAPRAVAPYKYASNVRSPHP--------AIQPLQAPQPAVHVQGQ--EPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSN--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGTVAAATS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZSR2-1", "uniprot_id": "D3ZSR2_RAT", "id": "D3ZSR2-1", "name": "Polyadenylate-binding protein", "aln": "--------------------MNAAASS-------YPMASLYVGDLHSDVTEVMLYEKFSPVGPVLSIRVCRDMIIRRSLGYAYVNFQQPADAERALDTMNFD-------------RDPSLRKSGVGNVFIKSLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAANKAIEKMNGMLLNDRKVFVGRFKSRKKREAELGAKA-KEFTNVYIKNFGEEVDDENLRELFSQFGKTLSVKVMRDCSGKSKGFGFVSYEKHEDARKAVEEMNGKEMS-GKSIFVGRAQKKVER---------QLK---------------RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSTKVML-EDGRSKGFGFDCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEEWKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGRPPYYTPNQLAQMRPNRRWQ-QGGRPQGFQGMP-SALRQSGPRP-------ALRHLAPTGNAPASRGLPTTAQRVGSECPDRL---------------------------------------------------------------------PLQAPQPAVHVQGQ--EPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSN--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGTVAAATS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13310-1", "uniprot_id": "PABP4_HUMAN", "id": "Q13310-1", "name": "Polyadenylate-binding protein 4", "aln": "--------------------MNAAASS-------YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA-KEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEIS-GKIIFVGRAQKKVERQAELKRKFEQLKQE----------RISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQ-QGGRPQGFQGMP-SAIRQSGPRP-------TLRHLAPTG----------------SECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHP--------AIQPLQAPQPAVHVQGQ--EPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSN--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G5E8X2-1", "uniprot_id": "G5E8X2_MOUSE", "id": "G5E8X2-1", "name": "Polyadenylate-binding protein 5", "aln": "--------------------MS-LEAK-------YRAASLYVGDLHEDVTEDMLFRKFSTVGPVLSIRICRDLISQRSLGYAYVNFLQVNDAQKALVTMNFDVIKGKSIRLMWSQRDACLRRSGVGNVFIKNLDKSIDNKTLYEHFSPFGTIMSSKVMTDGEG-SKGYGFVHYQDRRAADRAIEEMNGKLLRESTLFVARFKSRKDREAELRDKP-TEFTNVYIKNFGDDVDDEKLREVFSKYGQTLSVKVMKDATGKSKGFGFVSFDSHEAAKNAVEDMNGQDIN-GQTIFVGRAQKKVERQAELKEMFEQMKKE----------RIRARQAAKLYIKNLDDTIDDETLRKEFSVFGSICRVKVMQ-EAGQSKGFGLICFFSPEAAAKAMAEMNGRILGSKPLNIALGQKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L6B4-1", "uniprot_id": "A0ABK0L6B4_RAT", "id": "A0ABK0L6B4-1", "name": "Polyadenylate-binding protein 5", "aln": "--------------------MS-VETK-------YRAASLYVGDLHEDVTEDLLFRKFNTVGPVLSIRICRDLISHRSLGYGYVNFLQVGDAQKALETMNFDLIKGKSIRLMWSQRDACLRKSGIGNVFIKNLDKSIDNKTLYEHFSPFGKIMSSKVMTDEEG-SKGYGFVHYQDQRAADRAIEEMNGKLLRDSTLFVARFKSRKDREAELREKP-AEFTNVYIKNFGDDMDDESLRSVFSKYGQTLSVKVMKDASGKSKRFGFVSFDSHKAAKNAVEDMNGRDIN-GQTIFVGRAQKKVERQAELKEMFEQMKKE----------RIRARQAAKLYIKNLDDTIDDETLRKEFSVFGSICRVKVMQ-EAGQSKGFGLICFFSPEAAAKAMAEMNGRILGSKPLNIALGQKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CB38-1", "uniprot_id": "PAB4L_HUMAN", "id": "P0CB38-1", "name": "Polyadenylate-binding protein 4-like", "aln": "--------------------MN-VAAK-------YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKA-SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDIN-GQLIFVGRAQKKVERQAELKQMFEQLKRE----------RIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQ-EEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQRH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96DU9-1", "uniprot_id": "PABP5_HUMAN", "id": "Q96DU9-1", "name": "Polyadenylate-binding protein 5", "aln": "--------------------MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSID-GKVLYVGRAQKKIERLAELRRRFERLRLK----------EKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMM-EVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A5H0-1", "uniprot_id": "D4A5H0_RAT", "id": "D4A5H0-1", "name": "Polyadenylate-binding protein 5", "aln": "--------------------MGSGEPNTAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDHLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNFGDDIDDEKLKKLFSEYGPTESVKVIRDATGKSKGFGFVRYETHEAAQKAVLELHGKSID-GKVLCVGRAQKKIERLAELRRRFERLKLK----------DKTRPPGVPIYIKNLDETINDEKLKEEFSLFGSISRAKVMM-EVGQGKGFGVVCFSSFEEASKAVNEMNGRVVGSKTLHVTLGQAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21187-1", "uniprot_id": "PABP_DROME", "id": "P21187-1", "name": "Polyadenylate-binding protein", "aln": "------------------------------------MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKA-KLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQK----------RHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQIYQPNAAS---GFFVPTLP---SNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITG--------------QQTAAPNMQIPGAQIAGGAQQRTSNYKYTSNMRNP---------PVPQLHQTQPIPQQLQGKNSEKLIASLLANAKPQEQKQILGERLYPMIEHMHAN--LAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTEPAN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04147-1", "uniprot_id": "PABP_YEAST", "id": "P04147-1", "name": "Polyadenylate-binding protein, cytoplasmic and nuclear", "aln": "MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETK-AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELN-GEKLYVGRAQKKNERMHVLKKQYEAYRLE----------KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARN------------------------QMRYQQATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPK-------------------------------------------------------------------------------------------------------NGMPPQFRNGPVYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::****** .*.* *: * . * : *: ** . .*. :** .. *: :*: * **:.* **:*:*.:. *:.:::: .* ** *:*.:: : .* *:*..:**:: *. :* :** *. ::*. . ..* :: :.*:::**: .: :. .* :* * : . *: : ***: : * ** ::. .:. *. : .. ***: :* :::****: ::*: *. *: :* * .** : .:.:***. ** : . *: *: * * :::. *.* :::.* : ", "identical_positions": 86, "similar_positions": 116, "identity": "11.88%" }, { "cls_id": "homologset.agr.SGD:S000000968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q148W0-1", "uniprot_id": "AT8B1_MOUSE", "id": "Q148W0-1", "name": "Phospholipid-transporting ATPase IC", "aln": "----------------------------------------------------------------------------------------------------MSTER--DSETTFDEESQPNDEVVPYSDDETEDELEDQGSTVEPEQNRVNREAEKKRETFRKDCTWQVKANDRK--------------------------------------------------------FHEQPHFMNTKFFCIKESKYASNAIKTYKYNGFTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWK------NQSFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFIVLILVSAGLAIGHAYWEAQVGN----YSWYLYDGENATPSYRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG-----------DHRDASQHSHSKIELVDFSWN-------------------------------------------------TFADGKLAFYDHYLIEQIQSGK-------------------EPEVRQFFFLLSICHTVMVDRI---------------------------------------------------------------------------------------------------------------------DGQINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGSER--TYNVLAILDFNSDRKRMSIIVRTP------EGSIRLYCKGADTVIYERLHRMNP------------TKQETQDALDIFASETLRTLCLCYKEIEEKEFTEWNNKFMAASVASSNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLH----TRMENQRNRGGVSAKFAPPVYEPFFPP-----GENRALIITGSWLNEILLE-KKTKRS--KILKLKFPRTEEERRMRSQ---SRRRLEEKKEQ--RQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKRFFVSLLHGVLTSMVLFFIPLGAYLQTVGQDGEAPSDYQSFAVTVASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQ---WKRRQSVFRRGVSSRRS-----------------AYAFSHQRGYADLISSGRSIRKK---------------------------------------------------RSPLDAIIADGTAEYRRTVES----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA47-1", "uniprot_id": "AT8B1_RAT", "id": "D4AA47-1", "name": "Phospholipid-transporting ATPase IC", "aln": "----------------------------------------------------------------------------------------------------MNTER--DSETTFDEDSQPNDEVVPYSDDETEDELEDQGPAVEPEQNRVNREVEKKKETFRKDCTWQVKANDRK--------------------------------------------------------FHEQPHFMNTKFFCIKESKYASNAIKTYKYNALTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWR------NQSFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIIIVLILVSAGLAIGHAYWEAQIGN----YSWYLYDGENATPSYRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKSRTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG-----------DHRDASQHSHSKIELVDFSWN-------------------------------------------------EFADGKLAFYDHYLIEQIQSGK-------------------EPEVRQFFFLLSICHTVMVDRI---------------------------------------------------------------------------------------------------------------------DGQINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGTER--TYSVLAILDFNSDRKRMSIIVRTP------EGSIRLYCKGADTVIYERLHRMNP------------MKQETQDALDIFASETLRTLCLCYKEIEEKEFAEWNKKFMAASVASSNRDEALDKVYEEIERDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLH----TRMENQRNRGGVSAKFAPPAYEPFFPP-----GENRALIITGSWLNEILLE-KKTKRS--KILKLKFPRTEEERRMRSQ---SRRRLEEKKEQ--RQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKKFFVSLLHGVLTSMVLFFIPFGAYLQTVGQDGEAPSDYQSFAVTMASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQ---WKRRQSVFRRGASSRRS-----------------AYAFSHQRGYADLISSGRSIRKK---------------------------------------------------RSPLDAIIADGTAEYRRTVES----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43520-1", "uniprot_id": "AT8B1_HUMAN", "id": "O43520-1", "name": "Phospholipid-transporting ATPase IC", "aln": "----------------------------------------------------------------------------------------------------MSTER--DSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRKECTWQVKANDRK--------------------------------------------------------YHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWR------NTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGN----SSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG-----------DHRDASQHNHNKIEQVDFSWN-------------------------------------------------TYADGKLAFYDHYLIEQIQSGK-------------------EPEVRQFFFLLAVCHTVMVDRT---------------------------------------------------------------------------------------------------------------------DGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTER--TYNVLAILDFNSDRKRMSIIVRTP------EGNIKLYCKGADTVIYERLHRMNP------------TKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLH----ARMENQRNRGGVYAKFAPPVQESFFPP-----GGNRALIITGSWLNEILLE-KKTKRN--KILKLKFPRTEEERRMRTQ---SKRRLEAKKEQ--RQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQ---WQRRQQVFRRGVSTRRS-----------------AYAFSHQRGYADLISSGRSIRKK---------------------------------------------------RSPLDAIVADGTAEYRRTGDS----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFK0-1", "uniprot_id": "E7FFK0_DANRE", "id": "E7FFK0-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------MNSRSRADSQGSLDE---PDDEVMPYSDDETDAELED-----ELDQSVDQLPEPETRPAPAVEAGWSVRANDRE--------------------------------------------------------YCKRPEFQKKVFLCIKKSRYSGNAIKTYKYNVLTFLPLNLYEQFKRAANLYFLCLLVLQIIPQISTLPWYTTLVPLVLVLGITAIKDLVDDLARHRMDKEINNRKCDVLL------------------------------------------------------------------------------------------------------------NGRFVETRWMNLQVGDVVRLHKNDFIPADIMLLSTSNPNSLCYVETAELDGETNLKFKMGLKVTDERLQEEQQLSQFNALVMCEEPNNRLDKFVGTMIWE------SQSYALDLDNMLLRGCKVRNTDICHGLVIFAGNDTKIMRNGGKTRFKRTRIDKLMNYMVYTIFVLLVLLCAGLAIGHTYWYESIGS----KAWYLIDGLDYTSSYRGFLSFWGYIIILNTMVPISLYVSVEVIRLGQSKFINWDLQMYYADKDTPAKSRTTTLNEQLGQIEYIFSDKTGTLTQNIMAFKKCTISGRTYG-----------EPTTADGVSLDRGKPVDFSWN-------------------------------------------------KYADRKFQFEDHFLISCIRSKK-------------------DPQVLEFFKLLSLCHTVMVEEK---------------------------------------------------------------------------------------------------------------------EGELVYQAASPDEGALVTAARNFGFVFLSRTQDTITIQEMDKPQ--TYTMLALLDFNSDRKRMSIILKFP------DGRIRLYCKGADTVIYQRLSPQSK------------NKENTQEALDIFANETLRTLCLCYKDISQEEFDRWSRKHQTAAVSMVDRERELDEVYEEIEKDLLLIGATAIEDKLQDGVPETIAKLAKADIKIWVLTGDKKETAENIGYSCQLLTDDMKIHYGEDVNVQLR----NRQTQRRTDPQSRNKKQ---KESFFNE-----PGKNALIITGGWLNEILYE-KKKKRRRLRLKKLRLRQNNQQSSSSTAPDSSQPVDDWEKEK--RQEDFVDMACECSAVICCRVTPKQKANVVSLVKKYKKAVTLSIGDGANDVNMIKTADIGVGISGQEGMQAVMSSDYAFAQFCFLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWFSFFNGFSAQTAYEDWFITLYNVCYSSLPVLLVGLLDQDVNDKLSLRFPKLYLPGQQGALFNYRNFFISLFHGIFTSLMIFFIPYGAFLQTMGQDGEAPSDYQSFAVVAASSLIITVNLQISLNTSYWTFVNFFAVLGSIALYFGIMFDIHSAGIHVIFPNTFTFTGAASNALRQPYLWLTIILTVGVCLLPVICIQFLYQTIYPSVGDKVQRNRKKYELEDEEDERKKRKPTFQRGGRSRRS-----------------AYAFSHSRGYADLIASGRSIRQ----------------------------------------------------RPRVRPELRDSIREVPHAENI----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6UQ17-1", "uniprot_id": "AT8B3_MOUSE", "id": "Q6UQ17-1", "name": "Phospholipid-transporting ATPase IK", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MDGVHLGENLEDKDTEFTWEVKANDRT--------------------------------------------------------YHKQ--FKKKGFLCWRQKKYKSNAIHTAKYNIFSFLPLNLYEQFHRMSNLYFLFIIILQGIPEISTLPWFTLFAPLVCLFVIRATRDLVDDIGRHRSDKIINNRPCQILR------------------------------------------------------------------------------------------------------------GKSFLWKKWKNLCVGDVVCLSKDSIVPADLLLLASTEPSSLCYVETADIDGETNLKFRQALTVTHHELTSPKKMASFQGTVTCEEPNSRMHHFVGSLEWN------SRKYPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVALIFLSLVIASLLLTVGFTFMVKQFKA----KHYYMSPTHGRSDAMESFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLNMYYEPLDMPAKARSTSLNDQLGQVQYIFSDKTGTLTQNIMTFKKCCINGCIY---------------DSDDEHGTLRKRNPYAWN-------------------------------------------------PFADGKLQFYNKELESLVQGRQ-------------------DRAVQEFWRLLAICHTVMVQEK---------------------------------------------------------------------------------------------------------------------DNQLLYQAASPDEEALVTAARNFGYVFLSRTQDTITLVELGEER--VYQVLAMMDFNSVRKRMSVLVRNP------EGSICLYTKGADTVILERLRSKGV------------MEATTEEVLAAFAEQTLRTLCLAYKDVEEDAYKEWEPEHQEAALLLQNRAQALHQVYNKMEQNLQLLGATAIEDKLQDGVPETIKCLKKGNIKIWVLTGDKPETAVNIGFACQLLSENMIILEDKDINQVLERYWEDNVHQKAFKMMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEVAQEPVVSALDFLQKRRISQMWRNAGPSLGTSHSADSKIRESPEVQ--RERAFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRVCKFLRYFFYKTVASMMAQIWFSLVNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYMAGQKGELFNYSIFMQAITHGTITSMINFFVTV-MVSSDMSKAG-SSHDYQSLGVLVAISSLLSVTLEVMLVVKYWTLLFVGAVVLSLSSYVLMTSLTQSLWMYRISPKTFPFLFADYNVLFEPCSLLLIVLNVALNVLPMLALRTIHRTVLK------QRPKGEEEAPSEEVAVEPAMRHLRRGIPARRS-----------------SYAFSHREGYANLITQGTILRRQTHVDDSDGGTVCESLNPPEEDIPLQNKDSVFNPRKISILAKKRRHFFGKGSQEEVHPNTSSQTMEKQPTIHRDSETQKLPTTTSATSGKLLPSASEDEAFYSVASQYTLASQPKHTDVHSSFWKSPLWRDSASSSPSQLEVPRKQS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ANX3-1", "uniprot_id": "A2ANX3_MOUSE", "id": "A2ANX3-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNKKK--LLEVERVVKANDRD--------------------------------------------------------YNEK-------------FQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLI------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWK------DSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQF--RTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAG-------EVLDDPIQKKEITKEKEATDFSSK-------------------------------------------------SKSEKTLHFFDQSLMESIELG--------------------DPKVHEFLRLLALCHTVMSEENS--------------------------------------------------------------------------------------------------------------------AGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPV--TYQLLAFLDFNNIRKRMSVIVRNP------EGRIKLYSKGADTILFEKLHPSNED-----------LQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGE----VREELRKAKENLLGQSTSFSNGHAVYD-------NKQRLGLDAGAGEAVTG---------------------EYALVIN---GHSLAHALESD--VENDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAEDGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRRWQKAQRKKRP----LRSRRPQTRRSSSRRS-----------------GYAFAHQEGYGELITSGKNMRAK---------------------------------------------------SPAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98199-1", "uniprot_id": "AT8B2_MOUSE", "id": "P98199-1", "name": "Phospholipid-transporting ATPase ID", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MTVPKEIPEKWARAGAPPSWSQKKPSWGTEEERRARANDRE--------------------------------------------------------YNEK-------------FQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLI------------------------------------------------------------------------------------------------------------NGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELG-DVSQLARFDGEVICEPPNNKLDKFSGTLYWK------ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRF--QVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG--------DVFDVLGHKAELGERPEPVDFSFN-------------------------------------------------PLADKKFLFWDSSLLEAVKMG--------------------DPHTHEFFRLLSLCHTVMSEEKN--------------------------------------------------------------------------------------------------------------------EGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAI--TYQLLAILDFNNIRKRMSVIVRNP------EGKIRLYCKGADTILLDRLHPPTQE-----------LLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHTVLE----VREELRKARKKMVDSSHAVGNGFTYQG-------NLSSSKLTS-VLEAVAG---------------------EYALVIN---GHSLAHALEAD--MELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVRKKQKA----QHRCMRRVGRTGSRRS-----------------GYAFSHQEGFGELIMSGKNMRLS---------------------------------------------------SLALSS---FSTRSSSSWIESLRRKKSDSANSPSGGAEKPLKG------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3FIN4-1", "uniprot_id": "AT8B5_MOUSE", "id": "A3FIN4-1", "name": "Phospholipid-transporting ATPase FetA", "aln": "---------------------------------------------------------------------------------------------------------------------------------MKYVKAFVSEISWDCSWYCSAMQERRNEDRQKEEEERILQANNRR--------------------------------------------------------FNSL-------------FEYPDNSIKTSKYGFFNFLPMNLFEQFQRLANAYFLILLFLQLVPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHRSDQQINNRSVSILV------------------------------------------------------------------------------------------------------------NGRVEEIKWRNVQVGDIIKLENNHPVTADMLLLSSSEPYGLTYIETADLDGETNLKVKQAISVTSAMEDNLELLSSFNGEVRCDPPNNKLDKFSGTLSYL------GNTYLLNHERLLLRGCVIRNTDWCYGLVVYTGQDTKLMQNSGRSTFKRTHIDHLMNVLVVWIFMFLGGMCFLLSIGHGIWENSRGYYF--QAFLPWKHYITSSATSSALIFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNMPAQARTTTLNEELGQVQYVFSDKTGTLTENVMIFNKCSINGKTYG--------YSYDDNGEYVPKSP-KDKVDFSYN-------------------------------------------------HLADPKFSFYDKTLVEAVKSE--------------------DPLVYLFFLCLSLCHTVMSEEKV--------------------------------------------------------------------------------------------------------------------EGELVYQAQSPDEGALVTATRNFGFVFCSRTPETITVIEMGKIR--VYRLLAILDFSNERKRMSVIVRTP------EDRVMLFCKGADTIIYELLHPSCAS-----------LSEVTMDHLDDFASEGLRTLMVAYRELDKAYFQTWIKKHGEAWLTLENRERKLALVYEEIERDLMLLGATAIEDKLQRGVPETIVTLSKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDGVFMVEGTDRET----VLEELRTARKKMKPESLLESDPINMYL-------ARKPKMPFKSLDEVANG---------------------NYGLVIS---GYSLAYALEGS--LEFELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDISMIKAAHIGVGISNQEGMQATLSSDFSFCQFHFLQRLLLVHGRLSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPVLGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFVKCLLHGIYNSFVLFFVPMGTVFNSERNDGKDISDFQSFSLLVQTTLIGVMTMQIALRTTSWTMINHTFTWGSLGLYFCILILLCSDGLCLRYPSIFNFLGVARNSLSQPQIWLCLILSTILCMIPLIGYNFLRPLLWPINADKVLNRIHFCLKHPI----PTQVQTKIKHPSLRRS-----------------AYAFSHKQGFGALITSGKTLKSS---------------------------------------------------ALAKSK----------RFL------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "-----------------------------------------------MSGTFHGDGHAPMSPFEDTFQFEDNSSNEDTHIAPTHFDDGATSNKYSRPQVSFNDETPKNKREDAEEFTFNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTNYDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTKDDIDPGAINR------------AQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEANIVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIR-TSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRS---RFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRREKAEIAKDRDTMIDELRALS----------------------------------GNSQFYPEEVTFVSKEFVRDLKGASG---------------EVQQRCCEHFMLALALCHSVLVEANPDN------------------------------------------------------------------------------------------------------------------PKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQK--EFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSN-------SEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVK-------EFGSEPSEIVDALLSKYLKEYFNLTG-----SEEEIFEAKKDHEFPKG---------------------NYAIVIDG--DALKLALYGED--IRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWD----WFSGLFIALSCLVVFAWTGIWSSAIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQH-----------------GEKIIEGIALSDNLGGSNYSRDS------------------------------------------VVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8K2X1-1", "uniprot_id": "AT10D_MOUSE", "id": "Q8K2X1-1", "name": "Phospholipid-transporting ATPase VD", "aln": "-----------------------------------------------------------------------------------------------------------------------MTELLQWARHHWRRLSHGRAQGEDERPYNYAS---------LLACGGKSSRTPRPAG-------------------------------------------------KHRVVIPHLQCFKDE--YERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYS----------------------------------------------------------------------------------------------------------RKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEK-FSSRIECESPNNDLSRFRGFLEHAN-----KERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENML-FFNIPEPDGRVISPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDTLGGSLSNMARPRAQGCRTVP-SGPLG-KPSAQLSGSTSAVGNGEGSGEVPHSRQAAFSSPMETDVVPDTRLLDKFSQLTPQLLTGLDGT-AQSSPLETLY-IMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRR-SSSPSLASGKDSSSGTPCAFVSRISFFSRPKLSPPMEDESSQMDEIPQASN-SACCTETEAQNRAVGLSVSSAEALSGPPPSASNLCYEAESPDEAALVYAARAYRCTLQSRTPEQVMVDFAALGS-LTFQLLHILPFDSVRKRMSVVVRHPL-----SKQVVVYTKGADSVIMELLS-VAASDGTNPE-QQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGM--LMSAILEELQKRAQ--VSP---ELASS-------RKNFPQPSDAQGQG------------------------RAGLVIT---GKTLEFALQES--LQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHHHVLTLPIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSD-------IDIFTFGNPLNTAALFIILLHLVIESKSLTWIHMLVTVGSILSYFFFALAFGALCVTCNPPSNP--YGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRAKYFDRLPPEERAEALKRWRGTAK--------------------------VNHVASKHASQSAAMSGR-PTPGS----------------------------------------------SAVLAMKS---------ATVSTVEQ---STR---ETALD-----------RGCSEPGASKMTGSSAS----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P241-1", "uniprot_id": "AT10D_HUMAN", "id": "Q9P241-1", "name": "Phospholipid-transporting ATPase VD", "aln": "-----------------------------------------------------------------------------------------------------------------------MTEALQWARYHWRRLIRGATRDDDSGPYNYSS---------LLACGRKSSQTPKLSG-------------------------------------------------RHRIVVPHIQPFKDE--YEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYS----------------------------------------------------------------------------------------------------------RKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEK-FSSRIECESPNNDLSRFRGFLEHSN-----KERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMH-FFNVPEPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDTVSGSLSNMAKPRAPSCRTVH-NGPLGNKPSNHLAGSSFTLGSGEGASEVPHSRQAAFSSPIETDVVPDTRLLDKFSQITPRLFMPLDET-IQNPPMETLY-IIDFFIALAICNTVVVSAPNQPRQKIRHPSLGGLPIKSLEEIKSLFQRWSVRR-SSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQVCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQP-LACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGP-LTFQLLHILPFDSVRKRMSVVVRHPL-----SNQVVVYTKGADSVIMELLS-VASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGM--LMSTILKELQKKTQ--ALP---EQVSL-------SEDLLQPPVPRDSGL-----------------------RAGLIIT---GKTLEFALQES--LQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSD-------TDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNP--YWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRAKHFDRLTPEERTKALKKWRGAGK--------------------------MNQVTSKYANQSAGKSGRRPMPGP----------------------------------------------SAVFAMKS---------ASSCAIEQ---GNLSLCETALD-----------QGYSETKAFEMAGPSKGKES-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AWN4-1", "uniprot_id": "AT10B_MOUSE", "id": "B1AWN4-1", "name": "Phospholipid-transporting ATPase VB", "aln": "-----------------------------------------------------------------------------------------------------------------------MTCSLDFSWLRWKWRTQDGFS---QSPSETTP---------LLSP--ETDRQSHNTA-------------------------------------------------EQRVVYPNNSMCHQD--WKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYE----------------------------------------------------------------------------------------------------------RKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEH-FHSTIVCEKPNNHLSKFKGYMEHPD-----QTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHP-PFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWAQGSTTMRSQGGAQPLRRCHSARVPIQSHCRQRSVGRWETSQP-PVAFSSSIEKDVTPDKNLLSKVRDAALWLET-SDTRPAKPSHSTTAS-IADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQQLFQRLKLL--SLSQSFSSTAPSDTDLGESLGPNLPTIDSDEKDD--TSVCSG-DCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQGIC-LTFDLLFTLGFDSVRKRMSVVVRHPL-----TDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCES--ILNCTLEDIKRFHE--PQQPARKLCGH-------RIPPKMPSVNSGAMAP----------------------EIGLVID---GKTLNAIFQGK--LENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSD-------IDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNP--YWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQNWRSKQRPAPASASASASAPATGTVHTRPPCHPVPPEAQQNFGASTSKSSGPPRQKH----------------------------------------------VEDRVLQDPRCSREHSRDDTCTVDTL--AKLSSGECLLDPNRTVAPTAYSRGQKDVSRHSSKGSHRRSQSSLTI---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94823-1", "uniprot_id": "AT10B_HUMAN", "id": "O94823-1", "name": "Phospholipid-transporting ATPase VB", "aln": "-----------------------------------------------------------------------------------------------------------------------MALSVDSSWHRWQWRVRDGFP---HCPSETTP---------LLSP--EKGRQSYNLT-------------------------------------------------QQRVVFPNNSIFHQD--WEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYE----------------------------------------------------------------------------------------------------------RKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL-FHNTIVCEKPNNHLNKFKGYMEHPD-----QTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHP-PFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQP-PVAFSSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSS-IADFFLALTICNSVMVSTTTEPRQRVTIKPSSKALGTSLEKIQQLFQKLKLL--SLSQSFSSTAPSDTDLGESLGANVATTDSDERDD--ASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTC-LTFSLLCTLGFDSVRKRMSVVVRHPL-----TGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCES--ILNCALEELKQFRE--LQKPDRKLFGF-------RLPSKTPSITSEAVVP----------------------EAGLVID---GKTLNAIFQGK--LEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSD-------IDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNP--YWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVA------------RPTHHPVSSITGQDFSASTPKSSNPPKRKH----------------------------------------------VEESVLHEQRCGTECMRDDSCSGDSS--AQLSSGEHLLGPNRIMA---YSRGQTDMCRCSKRSSHRRSQSSLTI---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54827-1", "uniprot_id": "AT10A_MOUSE", "id": "O54827-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------MERELPAAEESASSGWRRPRRRRWEG--RTRTVRSN---------LLPPLGTEDSTIGAPK-------------------------------------------------GERLLM------------RGCIQHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFS----------------------------------------------------------------------------------------------------------REEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNNDLSRFRGYIMHSN-----GEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTH--------KTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASGCSSIGNLSTSKSSHKSGSAFLP---SLSQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQ--REQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPL-----TDEINVYTKGADSVVMDLLLPCSSDD--ARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAA--LLDQCLSYVQSRNPRSTLQNSESNLSV-------GFS-FNPVSTSTDASP----------------------SPSLVID---GRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSD-------VDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNP--YWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLGRQLAKKPLNKFSDPKETFAQGQPPGHSETELSERKTMGPFETLPRDCASQASQFTQQLTCSPEASGEPSAVDTNM---------------------------------PLRENTLLEGLGSQASGSSMPRGAIS---EVCPGDSKRQSTSASQTARLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSGSSLQMDKQDGEFLSNPPQPEQDLHSFQGQVTGYL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60312-1", "uniprot_id": "AT10A_HUMAN", "id": "O60312-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------MEREPAGTEEPGPPG----RRRRREG--RTRTVRSN---------LLPPPGAEDPAAGAAK-------------------------------------------------GERRRR------------RGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFS----------------------------------------------------------------------------------------------------------REEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNNDLSRFRGCIIHDN-----GKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVH--------RTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPS---TPSSDGMLLRLEERLGQPTSAIASNGYSSQADN---WASELAQEQES----------ERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPL-----TDEINVYTKGADSVVMDLLQPCSSVD--ARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAA--LLDQCLCYVQSRGLQRAPEKTKGKVSM-------RFSSLCPPSTSTASGR----------------------RPSLVID---GRSLAYALEKN--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSN-------VDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNP--YWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLS-----QPSWHTQQPVCSLEASGEPSTVDMSM---------------------------------PVREHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKVRAASTGRVTPLSSLFSLPTFSLLNWISSWSLVSRLGSVLQFSRTEQLADGQAG--RGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTG6-1", "uniprot_id": "Q7KTG6_DROME", "id": "Q7KTG6-1", "name": "Phospholipid-transporting ATPase", "aln": "MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYD----------------------------------------------------------------------------------------------------------GETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSK-FVSRVEADAPTTKLYRFHGALIHPT-----GERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFP----VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPP------------SELEKIYSKPGAPAPPLIPNDNLNSDMAQ--------LTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYR--------TADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIG-----SQEIVLYTKGADSSIMPVLVPCSHNS------PEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAET--AINFYLTDMENDKT-------TSTLGY-------GQSLRKKQ-------------------------------RALVVD---GKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESD-------VGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSS--YWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRGEALLVTWSRSTS----------------------------------------------------------------------------------------------------------------------------------------------------ASSIYRITDYGSKNQIITTIT----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** ..*:* *: *::. :* **: : .* . . *: :. : :* :* : * :* : * : ***.: : : ..**::** :::. . :::* :***:*:* : : : .: * . : : * : : ::** . ::**. *:*:::* :** : * . *:: :. * : . * :. . . * .:: . ::*::::: *. : : : :: :: .: ::***:.::*:*******:* * *.:* : * * : . :. : . :. **** *** :: : : . : : : :* : *.. ** ** ::: : ****: : * * * :* ** * :. : :. : * . : :* .: *:*.*.:**:** ** : * * . :.:*:***** *** **..:..:: . . :: * *:*** :* **: :* :*: **.****:**: **: *.:*:*::.:** **. :*: . :* .* :*:: ** .* *:..:: ::**. :*: : .:.. : : ::*: ::: * : .: :: : : * ** * : * : .. *. * .. : . : . : ::* . ", "identical_positions": 162, "similar_positions": 239, "identity": "8.44%" }, { "cls_id": "homologset.agr.SGD:S000000970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1J6-1", "uniprot_id": "TRNT1_MOUSE", "id": "Q8K1J6-1", "name": "CCA tRNA nucleotidyltransferase 1, mitochondrial", "aln": "---------------MQSVLYPWHRQVLRCSWSRLCL----------------LKRYLFTMKLQSPEFQSLFTEGLKSLTELFAKENH------ELRIAGGAVRDLLNGVKPQDVDFATTATP---------TQMKEMFQSAGIR-----MINNKGEK--HGTITARLH-EENFEVTTLRIDVTTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFN--GYADLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDRPGDHDHETLEAIAENAKGLAGISGERIWVELKKILTGDHVNHLIHLIYDLGVAPHIGLPA-NANLEEFN-KVSKNVEGFSP--KPMTLLASLFKVQDDVTKLDLRLKISKEEKNLG-LFIVKNRKDLIKATDSSEPLKPYQDFVIDSREPDATARVCELLKYQGEHGLLKEMQQWSVPPFPVSGHDIRKVGISSGKEIGALLQQLREQWKKSGYRMEKDELLSYIKKT------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQ33-1", "uniprot_id": "A0A8I5ZQ33_RAT", "id": "A0A8I5ZQ33-1", "name": "CCA tRNA nucleotidyltransferase 1, mitochondrial", "aln": "---------------MQSLLYPWHRQVLSCSWSRLCL----------------LKRYLFTMKLQSPEFQSLFTEGLKSLTELFAKENH------ELRIAGGAVRDLLNGVKPQDVDFATTATP---------TEMKEMFQAAGIR-----MINNKGEK--HGTIIARLH-EENFEVTTLRIDVSTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFN--GYADLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDRETLEAIAENAKGLAGISGERIWVELKKILTGDHVNHLIHLIYDLDVASHIGLPA-NANLEEFN-KVSKNVEGFSP--KPMTVLASLFKVQDDVTKLDLRLKISKEEKNLG-LFIVKNRKDLIKATDSSEPLKPYQDFVIDSREPDATARVCELLKYQGEHALLKEMQQWSVPPFPVSGHDIRKVGISSGKEIGALLQQLREQWKKSGYQMEKDELLNYIKKT------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96Q11-1", "uniprot_id": "TRNT1_HUMAN", "id": "Q96Q11-1", "name": "CCA tRNA nucleotidyltransferase 1, mitochondrial", "aln": "---------------MLRCLYHWHRPVLNRRWSRLCL----------------PKQYLFTMKLQSPEFQSLFTEGLKSLTELFVKENH------ELRIAGGAVRDLLNGVKPQDIDFATTATP---------TQMKEMFQSAGIR-----MINNRGEK--HGTITARLH-EENFEITTLRIDVTTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFN--GYEDLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDPETLEAIAENAKGLAGISGERIWVELKKILVGNHVNHLIHLIYDLDVAPYIGLPA-NASLEEFD-KVSKNVDGFSP--KPVTLLASLFKVQDDVTKLDLRLKIAKEEKNLG-LFIVKNRKDLIKATDSSDPLKPYQDFIIDSREPDATTRVCELLKYQGEHCLLKEMQQWSIPPFPVSGHDIRKVGISSGKEIGALLQQLREQWKKSGYQMEKDELLSYIKKT------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NXI9-1", "uniprot_id": "TRNT1_DANRE", "id": "F6NXI9-1", "name": "CCA tRNA nucleotidyltransferase 1, mitochondrial", "aln": "---------------MWAKLFLRPSFVNRVHLTWSC-------------------RALLTMQLKTKEFESLFTDGLVGLAEIFQKNQF------ELRIAGGAVRDLLSGKRPEDVDFATTATP---------EEMKSMFQTAGVR-----MINNKGEK--HGTITARLH-EENFEVTTLRVDVQTDGRHAEVEFTTDWQKDAERRDLTINSMFLGLDGTLYDYFQ--GYEDLKNRKVRFVGSASLRIQEDYLRILRYFRFYGRVAAEPGQHEPETLEAIRENARGLAGISGERIWVELKKMLVGNHAGHLLELVYELGLAQYTGLPA-DGDVEEMK-QVWQRAHVSSP--KPMTVLAALFRKQADVENLDQRLKVSREEKNLG-LFLVKYRRDLVKGHDEHDTMKPYTDFITDSREPDTQSKVLELLKYQGENKLLDELRRWSIPRFPVSGHDLRKLGYTSGKEIGTILQELRDMWKKSRYQMSKDELLSTLSQS------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNH2-1", "uniprot_id": "Q9VNH2_DROME", "id": "Q9VNH2-1", "name": "", "aln": "MNGPSLLVKLTTRAFLLFNGRPQNRWLKSMANSMVCSRGVSPELIAQLGKPPRMRTNPAFRKVATPEFKSIFTPELNDLVALFKKYDY------ELRIAGGAVRDILMGIPPKDIDLATTATP---------DQMKQMFEKEEVR-----MINANGEK--HGTITPRINDKENFEVTTLRIDIRTDGRHAEVMYTTDWQLDANRRDLTINSMFLGFDGTVYDYFY--GYDDLQERRVVFVGEADIRIKEDFLRILRYFRFYGRIASEENNHDKATLAAIKENAKGLARISGERIWSELQKIVPGNFGAALFLEMHRCNLFEYIGLPK-EPYLDEFD-RLCKALDQFEKPHQPILYLAGMLHSVEDAMEMHKRLKLSAYERDLA-RFITQERE---KVGSQYTTLRDYQKLCLQKYIQ--RDFVEQLLKYSGKLELYNQLKSWVKPDFPIRGNALAQRGLN-GMRLGLVMDELKLLWADSDFQLTHDDLLKWIPNVLKKIPSAPGKVKRMK---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21269-1", "uniprot_id": "CCA1_YEAST", "id": "P21269-1", "name": "CCA tRNA nucleotidyltransferase, mitochondrial", "aln": "------------------MLRSTISLLMNSAAQKTMTN---------------SNFVLNAPKITLTKVEQNICNLLNDYTDLYNQKYHNKPEPLTLRITGGWVRDKLLGQGSHDLDIAINVMSGEQFATGLNEYLQQHYAKYGAKPHNIHKIDKNPEKSKHLETATTKLFGVEVDFVNLRSEKYTELSRIPKVCFGTPEEDALRRDATLNALFYNIHKGEVEDFTKRGLQDLKDGVLRTPLPAKQTFLDDPLRVLRLIRFASRFNFTIDPEVMAEMGDPQINVAFNSKISRERVGVEMEKILVGPTPLLALQLIQRAHLENVIFFWHNDSSVVKFNEENCQDMDKINHVYNDNILNSHLKSFIELYPMFLEKLPILREKIGRSPGFQQNFILSAILSPMANLQIIGNPKKKINNLVSVTESIVKEGLKLSKNDAAVIAKTVDSICSYEEILAKFADRSQLKKSEIGIFLRNFNGEWETAHFASLSDAFLKIPKLETKKIELLFQNYNEFYSYIFDNNLNNCHELKPIVDGKQMAKLLQMKPGPWLGKINNEAIRWQFDNPTGTDQELITHLKAILPKYL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :.:. : * . . :: : . ***:** *** * * ..*:*:* .. . ::. : : *: . ** * . :.:...** : *: : : ** *** *:*::* .:. : * * **:: : *. : :* **:** :** .*. . . : *. : ** **: *::*:: * : : : : : : ::. . : . . : : : : :* : : . . * : : . :. * : ** . : : : . . .:* .: ::. * : : * :*. ", "identical_positions": 59, "similar_positions": 112, "identity": "10.19%" }, { "cls_id": "homologset.agr.SGD:S000000971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LS62-1", "uniprot_id": "F1LS62_RAT", "id": "F1LS62-1", "name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "aln": "--MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVTGQSGLFTQYNIQ-KKPMTVKEFRQLANS--------------------------------------SKYCTPRYLDYEDLER---------KYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRRKKLRKAP--------KSLQGNK----------------------SLSKRPKAEEDEEFAEFI-GEEVSSPAVCPRHLKVTEKPEK-FKLANIGASSE--KEASDTRIQVDQSLTN---DTKLSGKSCINSSVIDEIQPENDTANAVTS-PSTLKKASDLIPFSHGHITGKESRLLKILQLESPKIPSSLAE--------SNRVLTEGEENDEEGHASNLEP--------------GEVPDAL----------------SEE--RNGLNVPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLM----PYYK---PDNSKEENDSRWETAVNEVVQSGRKTKPIIPEMCFIYSEENVEYSPPNAFLEEDGTSLLISCSKCFVRVHASCYGVPSHEVCDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNQWAHVICAVAVPEVRFTNVPERTQIDVDRIPLQRLKLKCIFCRQRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHRVNSNVKSKTCEKAISVGQTVITKHRNTRYYSCRVIDVTSQIFYEVMFDDGSFSRDTFPEDIVSRNCVKLGPPAEGEVIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADVIQGERKRQRVLSSRLKNEYVDDPVYRTFLKSSFQKKCQKRQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCD7-1", "uniprot_id": "KDM4C_MOUSE", "id": "Q8VCD7-1", "name": "Lysine-specific demethylase 4C", "aln": "--MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVTGQSGLFTQYNIQ-KKAMTVKEFRQLANS--------------------------------------SKYCTPRYLDYEDLER---------KYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRKKKLRKPP--------KSLQGNK----------------------PLCKRPKPEEDEEFAEFS-GEEGANPAMGPRHLKVTEKPEKALKLGKLEESSA--KEALDTRIQVDQSLLN---DTKLSGKGCISSSVTAEIPPEDNRASAVIS-PSQLKEGADCIPLSHGHQAGKESHLLKILKLESPKIPSPLPE--------SNKVLTEGEENDEEGHGSNLEP--------------GEIPEAL----------------SEE--RNGLNIPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLM----PYYK---PDSSKEENDSRWETAVNEVVQSGRKTKPIIPEMCFIYSEENVDYSPPNAFLEEDGTSLLISCAKCFVRVHASCYGVPSHEVCDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNQWAHVICAVAVPEVRFTNVPERTQIDVDRIPLQRLKLKCIFCRHRVKKVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHRVNSNAKSKTCEKAISVGQTVITKHRNTRYYSCRVIDVTSQTFYEVMFDDGSFSRDTFPEDIVSRNCVKLGPPAEGEVIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADVIQGERKRQRVLSSRLKNEYVDDPVYRTFLKSSFQKKCQKRQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3R0-1", "uniprot_id": "KDM4C_HUMAN", "id": "Q9H3R0-1", "name": "Lysine-specific demethylase 4C", "aln": "--MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVTGQSGLFTQYNIQ-KKAMTVKEFRQLANS--------------------------------------GKYCTPRYLDYEDLER---------KYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKAS--------RSFQCAR----------------------STSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSE--EESSASRMQVEQNLSD---HIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSISSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAE--------SNGVLTEGEESDVESHGNGLEP--------------GEIPAVP----------------SGE--RNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLM----PYHK---PDSSNEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW72-1", "uniprot_id": "KDM4A_MOUSE", "id": "Q8BW72-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-TSYDDIDDL---VIPAPIQQLVTGQSGLFTQYNIQ-KKAMTVREFRKIANS--------------------------------------DKYCTPRYSEFEELER---------KYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEE-CPEEDVEAADQGEE----------------------GDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVK---------KKRSAPRSI----------------SEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHP--LVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQ----TYHQ---VEFG---AFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5I7-1", "uniprot_id": "A0A0G2K5I7_RAT", "id": "A0A0G2K5I7-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-TSYDDIDDL---VIPAPIQQLVTGQSGLFTQYNIQ-KKAMTVREFRKIANS--------------------------------------DKYCTPRYSEFEELER---------KYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSTVIDHTLPTPEAAEFLKDSG-LTPRAGNEE-CPEEDSEAAEQGEE----------------------GDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECQATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEDEEPEAAALDLSVNPESVEGRLVFSGSKKKASSSLGSSSSQDSVSSDSETTESVSCQGQEKT-VLTVHSYSRGDGKAAPGEPSVK---------RQRSAPRSI----------------SEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHP--LVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNELMAQQAPHCAVCMIFQ----TYHQ---VEFG---GFSQSCGNASEPAAQPQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75164-1", "uniprot_id": "KDM4A_HUMAN", "id": "O75164-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-ASYDDIDDL---VIPAPIQQLVTGQSGLFTQYNIQ-KKAMTVREFRKIANS--------------------------------------DKYCTPRYSEFEELER---------KYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESE-LPPRAGNEEECPEEDMEGVEDGEE----------------------GDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPCTR---------KKGSAARSF----------------SERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQ----TYHQ---VEFG---GFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VY5-1", "uniprot_id": "KDM4B_MOUSE", "id": "Q91VY5-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVTGQSGLFTQYNIQ-KKAMTVGEYRRLANS--------------------------------------EKYCTPRHQDFDDLER---------KYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKLLRRQISVKESRPWRKAEEERR------REPTRRPGPASHRRRSQPKKSKPEESRSPGEATAGVSTLDEARGCSRGEA----MPEDEEEEELLPSQGHEAEGVEEDGRGKPRPTKARNKKKTPSP-SSPPLLSAPPALFPTEEVLRPPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQ---------------LAPMEL-GPEE----------ENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-AFLFSGEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFY----PYSQSVQTER---------DSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRAS--GAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RB75-1", "uniprot_id": "M0RB75_RAT", "id": "M0RB75-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVTGQSGLFTQYNIQ-KKAMTVGEYRRLANS--------------------------------------EKYCTPRHQDFDDLER---------KYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRET----MPEEEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKKTPSL-LSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQ---------------LAPMEL-GPEE----------EDQAQAGDSQGTTSFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-AFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFY----PYSQSVQTEREVLATPG--DSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRAS--GAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDGVKAAKRPRVATVLATTTEDTGRSPEYLAFMESLLQAQGQPGAPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94953-1", "uniprot_id": "KDM4B_HUMAN", "id": "O94953-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVTGQSGLFTQYNIQ-KKAMTVGEYRRLANS--------------------------------------EKYCTPRHQDFDDLER---------KYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKLLRR----------------------------------SHRKRSQPKKPKPEDPKFPGEGTAGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVLGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGKAAFNQEHVSCQQAFEHFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-ASPFSGEEDVSDPDALRPLLSLQWKNRAASFQAERKFNAAAARTEPYCAICTLFY----PYCQALQTEKEAPIASLGKGCPATLPSKSRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHKSG--GHAVQLLRAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGSYSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAKRPRVGTPLAT--EDSGRSQDYVAFVESLLQVQGRPGAPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPD8-1", "uniprot_id": "KDM4F_HUMAN", "id": "A0A1W2PPD8-1", "name": "Probable lysine-specific demethylase 4F", "aln": "---MKSVHSSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKAR-QMYDDIEDI---LIATPLQQVTSGQGGVFTQYHKK-KKAMRVGQYRHLANS--------------------------------------KKYQTPPHQNFADLEQ---------RYWKSHPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNWR-------------------------------------------------------------------------------------------------------------------------------------------EDIALRRAALGLRHLRNHITSCPTRTVAPR---LCYNPKGG---GTDAVPGSAIQA-----------LETSAWVLPPSTGRWGPC-----------------------------------------------RGCGRGRG------RGRGRGRRPRELG--------------------TEETTVQSAAKRRLSVGTGSRAPGRKPQLQFADEALTDKPAPLSGGLPHFAKA-----------------------------SGCCCAPDLQPLGPPLDPDEPMHPGPCLLSLDSTASSLPLVVPMTPPSVTVPLITLSRDTGGDWKSPVNLAKVVAMDHSYASRVPVPTKFSRISWAPDSSAGAKARQRYATEFGDIFLQCMINPLDPWPLNMVSNVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RXH2-1", "uniprot_id": "KDM4E_HUMAN", "id": "B2RXH2-1", "name": "Lysine-specific demethylase 4E", "aln": "---MKSVHSSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKAR-QMYDDIEDI---LIATPLQQVTSGQGGVFTQYHKK-KKAMRVGQYRRLANS--------------------------------------KKYQTPPHQNFADLEQ---------RYWKSHPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNWR-------------------------------------------------------------------------------------------------------------------------------------------DDIVLRRAALGLRLLPNLTAQCPTQPVSSG---HCYNPKGC---GTDAVPGSAFQSSAYHTQTQSLTLGMSARVLLPSTGSWGSG-----------------------------------------------RGRGRGQGQGRGCSRGRGHGCCTRELG--------------------TEEPTVQPASKRRLLMGTRSRAQGHRPQLPLANDLMTN------------------------------------------------------------------------LSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6B0I6-1", "uniprot_id": "KDM4D_HUMAN", "id": "Q6B0I6-1", "name": "Lysine-specific demethylase 4D", "aln": "METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKAR-ETYDNISEI---LIATPLQQVASGRAGVFTQYHKK-KKAMTVGEYRHLANS--------------------------------------KKYQTPPHQNFEDLER---------KYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQK-------------------------------------------------------------------------------------------------------------------------------------------EVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQP-------------RAAAVHSSKKPSSTPS-----------------------------------------------STPGPSAQIIHPSNGRRGRGRPPQKLR--------------------AQELTLQTPAKRPLLAGTTCTASGPEPEPLPEDGALMDKPVP--------------------------------------------------------------------LSPG---------------------------------------------------LQHPVKASGCSWAPVP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5Q5-1", "uniprot_id": "KDM4D_RAT", "id": "A1A5Q5-1", "name": "Lysine-specific demethylase 4D", "aln": "---MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRAR-QSYDNISNI---LIATPLQQVVSGQAGVFTQYHKK-KKAMTVGQYRHLANS--------------------------------------KKYQTPPHLDFEDLER---------KYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWR-------------------------------------------------------------------------------------------------------------------------------------------VIQAPR-KTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQE--------------SDPAIAPPYPLGLSS-----------------------------------------------PGHMSTGK--------RGLGRRPCELG--------------------VQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSD--------------------------------------------------------------------LVNPG---------------------------------------------------PQHPVTASEGGLTSDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2K5-1", "uniprot_id": "KDM4D_MOUSE", "id": "Q3U2K5-1", "name": "Lysine-specific demethylase 4D", "aln": "---MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRAR-QSYDNISNI---LIATPLQQVVSGQAGVFTQYHKK-KKGMTVGEYRELANS--------------------------------------KKYQTPPHLDFEDLER---------KYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLERLARELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYELWKRGQDQAVVDHTETMVSTSQELTTRR-------------------------------------------------------------------------------------------------------------------------------------------VTKAPR-KTWGLKRLRLRQVSRSLLPIATVSNVPCNMQVCHTSRQPSDVKGDDVQK--------------SDSARASPHPLSLPS-----------------------------------------------SGHMSTRR--------CSLGRRPCELG--------------------AQESSNGAPVKRQLPAGRDDTSPSPELQPQAVSGDLIVDSG--------------------------------------------------------------------LVNPG---------------------------------------------------PQHLMTASEGGLTSDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V333-1", "uniprot_id": "KDM4A_DROME", "id": "Q9V333-1", "name": "Probable lysine-specific demethylase 4A", "aln": "MSTRSSFADEEQNKVPRIMTFRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVPRKSGY-DIDNIN-MTIPAPICQVVTGAHGVYQQINIQQRRQMTLRQFMEKANS--------------------------------------ELHQTPRHFDYDDLER---------KYWKNITYISPLYAADVKGSLSDEDLDVWNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYSINYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYNKITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCRSDMVKISMETFVRRFQPERYDNWLKGQDMGCHPEEP-GKICAAAP----------------------------------------------------------------------------------------------------------------------------------------------------PTLNEYEKQENLRA--------------------AKSEEESPQKRGCSLAG---------------NGCERNAES-----------------------------------------------------------AEDVDD-----KASVSSYSS---------------------CRQLQPVVKLRKLPTIASVPEPSSAPKRYDFN-TEAVVRVKRLWN---------------------------------------------------------------------------------------------------------------------------ELPCPDRGANLLTNGVVKNTKRMRFQTKVLTLDDED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V6L0-1", "uniprot_id": "KDM4B_DROME", "id": "Q9V6L0-1", "name": "Probable lysine-specific demethylase 4B", "aln": "---------MKMSEVPRIKVFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPEWVPRRSGYADLDALN-VTIPAPICQVVTGKQGYYQQINIQ-KKPLTVKQFSELAST--------------------------------------ERYATPKHFDFEDLER---------KYWKNITYVAPIYGADVSGSITDTDQDSWNINRLGTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQHDVPVSKITQEAGEIMITFPFGYHAGFNHGFNCAESTNFAMERWIEYGKRAVQCTCSNDMVKISMDTFVKRFQSDRYDLWMEGRDVGRHPEDPPNAVLSAAPLPPHLDVLLCDKKM----------------------------------------------------------------------------------------------------------------------KKQCNPTKAKSFKERNPDLDLDEIQQNPNVPDDVKAMLKESVLTLDTGDLATDEADFPNEDAMSLQSPANLKTKQELLEYIDDGTEDDDEEEDFKR-----------------------------------------------RKQKRRYDADYDDDWLASKRKTNSRNN---------------------RGRSPRTKDDRSISPASSTSSTSRGARRGKASGTPRKTPARRKKDSIT---------------------------------------------------------------------------------------------------------------------TSPAVSSAATAVKTPTSAVVAGTTSIATTTTPPADGGGGESSSLGSHCTTASP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39956-1", "uniprot_id": "RPH1_YEAST", "id": "P39956-1", "name": "DNA damage-responsive transcriptional repressor RPH1", "aln": "----MTKLIAPSEIVGGVPVFKPTYEQFEDFYAYCKAINKYG-MKSGVVKVIPPKEWKDKLDLPYSAETLQKIKIKSPIQQHISGNKGLFMVQNVEKNKTYNIIQWKDLSKDYVPPEDPKARRNSRKGSVSKSTKLKLKNFESSFNIDDFEQFRTEYTIDLSDFQNTERLKFLEEYYWKTLNFTTPMYGADTPGSIFPEGLNVWNVAKLPNILDHMETK----VPGVNDSYLYAGLWKASFSWHLEDQDLYSINYIHFGAPKQWYSIPQEDRFKFYKFMQEQFPEEAKNCPEFLRHKMFLASPKLLQENGIRCNEIVHHEGEFMITYPYGYHAGFNYGYNLAESVNFALEEWLPIGKKAGKCHCISDSVEIDVKKLAKSWR-DNNKESKGTPPLNQLPNPAMPLLHRPTLKEME--------------------------------------------------------------------------------------------------------------------------------------------SSSLRSTSPDVGHFSNFKSKSSGVSSPLLSRMKDYSNIVEPTLEDPTLKLKRISSFQEQPLNKLLKRETSQTAMLTDHEDNIVA------------------------------------------------MSLTSMANSAASSPRLPLSRLNSSNE-------------------LSNAQPLLDMTNNTLAFPRPNGPSGLNPLLYISNKNISGISHSAPHSPVN---------------------------------------------------------------------------------------------------------------------PNISLIKRVKSPNIVTLNISRESSRSPIALNYEARQQHSQQHSFSTPSTVSNLSTSVLG-PLSDTNDIKTPHPERPNHKTANRILKKESPVETSKSNLILSKVASTRQEDSFTSRNDDLDKEQGSSPLNSKFAPEEIVLSGKNKIYICKECQRKFSSG--------------------------------------HHLTRHKKSVHSGEKPHSCPKCGKRFKRRDHVLQHLNKKIPCISNETTVDAPIMNPTVQPQDGKAAINQQSTPLN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *: ::* :* * ::. * :*:.*: ** ** : . . : * :*: * :* * : : : .: : :: :. . * : :::. ***. .*:*.** *:: **: * .: : :: . : *** .*** *:**::*:** ** *******:*:* ** ** :* :: . *. : * :****: : ** :*:: .: . :.:. **:*:*:*:*******:*:* **: *** .*: ** * * * . * :.:. :.: : : . : . ", "identical_positions": 92, "similar_positions": 98, "identity": "7.71%" }, { "cls_id": "homologset.agr.SGD:S000000972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUR9-1", "uniprot_id": "KAD4_MOUSE", "id": "Q9WUR9-1", "name": "Adenylate kinase 4, mitochondrial", "aln": "---------MASKLLRAVILGPPGSGKGTVCERIAQNF-GLQHLSSGHLLRENLKTGTEVGDVAKQYLEKGLLVPDHVITRLMMSELETR----SAQHWLLDGFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTETNRIWPYVYTLFSNKITPIQSKEAY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUS0-1", "uniprot_id": "KAD4_RAT", "id": "Q9WUS0-1", "name": "Adenylate kinase 4, mitochondrial", "aln": "---------MASKLLRAVILGPPGSGKGTVCERIAQNF-GLQHLSSGHLLRENLKTNTEVGDVAKQYLEKGLLVPDHVITRLMMSELETR----SAQHWLLDGFPRTLVQAEALDRICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVLGVDDITGEPLVQQEDDKPEALAARLRRYKDAAKPVIELYKSRGVLHQFSGTETNRIWPYVYTLFSNKITPIQSKEAY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27144-1", "uniprot_id": "KAD4_HUMAN", "id": "P27144-1", "name": "Adenylate kinase 4, mitochondrial", "aln": "---------MASKLLRAVILGPPGSGKGTVCQRIAQNF-GLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENR----RGQHWLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5KW96-1", "uniprot_id": "A0A8I5KW96_HUMAN", "id": "A0A8I5KW96-1", "name": "Adenylate kinase 4, mitochondrial", "aln": "---------MASKLLRAVILGPPGSGKGTVCQRIAQNF-GLQHLSSGHFLRENIKASTEVGEVAKQYIEKSLLVPDHVITRLMMSELENR----RGQHWLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDAAKPVIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTP7-1", "uniprot_id": "KAD3_MOUSE", "id": "Q9WTP7-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASGRLLRAVIMGAPGSGKGTVSSRITKHF-ELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDVMTRLALHELKTL----TQCSWLLDGFPRTLPQAEALDKVYQ-----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIWPHVYSFLQTKVPETTQKASVTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29411-1", "uniprot_id": "KAD3_RAT", "id": "P29411-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASGRLLRAVIMGAPGSGKGTGSSRITKHF-ELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIPDDDMTRLALHELKNL----TQCSWLLDGFPRTLPQAEALDRVYQ-----IDTVINLNVPFEVIKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIJ7-1", "uniprot_id": "KAD3_HUMAN", "id": "Q9UIJ7-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASARLLRAVIMGAPGSGKGTVSSRITTHF-ELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNL----TQYSWLLDGFPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGU6-1", "uniprot_id": "KAD3_DROME", "id": "Q9VGU6-1", "name": "GTP:AMP phosphotransferase, mitochondrial", "aln": "---------MFTKIFRAVIIGAPGSGKGTISELICKNH-GCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEV----GNRSYILDGFPRNIAQAEALAAREQ-----IDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKEIWPMMELFLNDRINA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26364-1", "uniprot_id": "KAD3_YEAST", "id": "P26364-1", "name": "GTP:AMP phosphotransferase, mitochondrial", "aln": "MKADAKQITHLLKPLRLLLLGAPGSGKGTQTSRLLKQIPQLSSISSGDILRQEIKSESTLGREATTYIAQGKLLPDDLITRLITFRLSALGWLKPSAMWLLDGFPRTTAQASALDELLKQHDASLNLVVELDVPESTILERIENRYVHVPSGRVYNLQYNPPKVPGLDDITGEPLTKRLDDTAEVFKKRLEEYKKTNEPLKDYYKKSGIFGTVSGETSDIIFRNY-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :::*.******* . : : :*:*.:**::: : :. *. :: :. *:** :*: .: ::******. **.** . :: *: *::* ..: *: *::* .******: :: *:. * **:***** :: **..... **. *. .*: *:. *:. ..* :. * ", "identical_positions": 59, "similar_positions": 71, "identity": "24.18%" }, { "cls_id": "homologset.agr.SGD:S000000973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AH26-1", "uniprot_id": "A0A8I6AH26_RAT", "id": "A0A8I6AH26-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "MTGRLSQWHREEGGALGHAPSLNIQEAGEWTPGQAAMKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDTHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTITNPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08811-1", "uniprot_id": "ERCC2_MOUSE", "id": "O08811-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDIHGRQMPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASVARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPVLHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18074-1", "uniprot_id": "ERCC2_HUMAN", "id": "P18074-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHD--TSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLE-------------SEETLKRIEQIAQQL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVP9-1", "uniprot_id": "Q7KVP9_DROME", "id": "Q7KVP9-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLSVDGLLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMD--TETPICQYFEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDT-DMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRRMAQPFTREDQLGISLLTLAQLENM-----------EQEKLERQAQGKQGVGGEVQEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06839-1", "uniprot_id": "RAD3_YEAST", "id": "P06839-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD/RAD3", "aln": "------------------------------------MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQMHYP-EHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFEKLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNIDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLHSADILTDQEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSFLQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLIIEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFSR--KRSQLPKWIAQGLSDADLNLSTDMAISNTKQFLRTMAQPTDPKDQEGVSVWSYEDLIKHQNSRKDQGGFIENENKEGEQDEDEDEDIEMQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :*.* * *** *****: ** ::*::**. *: :**********.:**:* :** :* *:******:.****.: **.:*: : :. * ** *:****:*:****: * *. ** ** :* . : : : * :. *.:.* : : ** *::.::.* . : ****:.* * .::::************: **:*:::.: *:************:*:*:.:. :: *. : * : : ::: * ::*.:**.::*:**:.*. : : : .****:::* *.:**.** *:**:.**:*::**:* *::* **:.*:* .**. : . *:*******:*** *::***:::: :: .*. :: ****:*** :** :****:: ...::.**:::*:*:*:*:*: ***.**.:*:*****:**:*:**::*:*..* :::****: .: ***: :*.***:***:** *:* :::****.:*:*.: .***:* **.** *:** *: * **:: : : **:::** * *** ** .* :**. ****:**:*********:** *:***:*:*:*:*: **:********:::*::::*******:**********:**.:*** ***:*::**:**:* **.:**:** : * *: **:.: .:. :: :** **** :** *:*: : :* .:*. : : : ", "identical_positions": 345, "similar_positions": 250, "identity": "42.12%" }, { "cls_id": "homologset.agr.SGD:S000000974", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P4T2-1", "uniprot_id": "U520_MOUSE", "id": "Q6P4T2-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDMNKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRREIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEPEKERIVGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEK---VHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGGHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LNJ2-1", "uniprot_id": "U520_RAT", "id": "F1LNJ2-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRREIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKARLVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGGHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75643-1", "uniprot_id": "U520_HUMAN", "id": "O75643-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRKEIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEK---VHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S754-1", "uniprot_id": "B0S754_DANRE", "id": "B0S754-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTKMGDRSQRTKPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEILLSFIQAALG-DQPRDILCGAADEVLAVLK-NDKMRD---KERRREVEQLLGP-TDDTRYHVLVNLGKKISDYGGDKE--------LQNMDDNIDET----YGVNVQFESDEEEGDEDQYGEVRDEGSDD-SEGEEADESSTLTANLGNTGDVMMTKKKD--LHPRDIDAFWLQRQLS--RFYNDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKEKIINKMEADQDLSKVLYQLQETEKEDIIREERSRRERMRKSRVD-DLESMDIDHG-ESVSSRQLLDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFGDEETLVGIEKLPKYAQAGFEG--FKSLNRIQSKLFKTTMETDENLLVCAPTGAGKTNVALMAMLREIGKHIN-MDGTINVADFKIIYIAPMRSLVQEMVGSFGKRLASYGIIVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQEDVRLIGLSATLPNYEDVATCLRVDPSKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDSKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLADMLNAEIVLGNVQNAKDAVNWLGYTYLYVRMLRNPTLYGVSHDDRSIDPLLERRRMDLVHTAATVLEKNNLVKYDKRSGSFQVTDLGRIASHFYITHESIMTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLSRGWAQLTDKTLNLCKMIDKRMWQSMSPLRQFRKLPEEVIKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDK---IHGSSEAFWILVEDVDSEVVLHHEYFLLKAKYAQDEHLVTFFVPVFEP----LPPQYFIRIASDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNGAFESLYQN-FPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNAEGRCVYITPMEALAEQVFLDWHQKFQENLNKKVVLLTG-ETSTDLKLLGKGDIIVSTPDKWDILSRRWKQRKNVQNVSLFIIDEVHLIG-GDNGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSK-PVLVFVPSRRQTRLTAIDILTFCAADVVPQRFLHSTEKDLVPFMENLSDVTLKETLSNGVGYLHEGLSPTERRIVEHLFTSGAIQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLQDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLRQLPHFTSELIKRCTDKGVESIFDIMEMEDEDRTGLLQLSDVQVADVARFCNRYPNIELSYEVVDKDDIKSGSPVVVQVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTL-QQKAKVKLDFVAPVVGVHNYTLYFMSDAYMGCDQEYKFSTEVKEADSEGDSDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUV9-1", "uniprot_id": "U520_DROME", "id": "Q9VUV9-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADAAARQLQYEYKANSNLVLQADVRLIER---PRRDEATGEVCSLVGKLDGTRMGDRYQRTKPEKTEERKVKRQKRDEAQYDFERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVLLSFIQEALG-DQPRDILCGAADEILAVLK-NDRLKD---RERKKDIDSLLGA-VTDERFALLVNLGKKITDFGSDAVNA---LTAAPNNEEQIDET----YGINVQFEESEEESDNDMYGEIRDDDAQD--EGEEARIDHTLHAENLANEEAANNVKKERSLHPLDIDAYWLQRCLS--KFYKDAMVSQSKAADVLKILKDAADD-RDCENQLVLLLGYDCFDFIKQLKLNRQMVLYCTMLASAQTDSERQRIREKMRGNSALAKILRQLDTGKSEDQEEGEARGSKRGKG-----DAEDGGAAAAGQVAGVRQLLELEEMAFTQGSHFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEG--FKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHIN-EDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHDERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGR-NQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSHDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLLKQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERVPIPIKESIEEHSAKVNVLLQAYISQLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKMPDEIAKKLEKKHFPWGRLYDLE-PHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTLRVELTITPDFQWDEK---VHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQLKFFVPVFEP----LPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFADWHSKFGS-LDIKVVKLTG-ETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQLVG-GEEGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPIPLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHK-PVIVFVSSRKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKKFINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDHLSELVENTLSDLEQSKCISVEDDMDTLP----------------LNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLLEIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQLGPELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWSKDSYLKQLPHFSPEIVKRCTEKKIETVFDIMELEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGSTVNVVVQLEREDE-VTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTL-QQKAKVKLDFVAPSPGKHDYTLYYMSDSYLGCDQEYKFSIEVGDFQSESESESD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32639-1", "uniprot_id": "BRR2_YEAST", "id": "P32639-1", "name": "Pre-mRNA-splicing helicase BRR2", "aln": "MTEHETKDKAKKIREIYRYDEMSNKVLKVDKRFMNTSQNPQRDAEISQPKSMSGRISAKDMGQGLCNNINKGLKENDVAVEKTGKSASLKKIQQHNTILNS--SSDFRLHYYPKDPSNVETYEQILQWVTEVLGNDIPHDLIIGTADIFIRQLKENEENEDGNIEERKEKIQHELGINIDSLKFNELVKLMKNITDYETHPDNSNKQAVAILADDEKSDEEEVTEMSNNANVLGGEINDNEDDDEEYDYNDVEVNSKKKNKRALPNIENDIIKLSDSKTSNIES--VPIYSIDEFFLQRKLRSELGYKDTSVIQDLSEKILNDIETLEHNPVALEQKLVDLLKFENISLAEFILKNRSTIFWGIRLAKS-TENEIPNLIEKMVAK-GLNDLVEQYKFRETTHSKRELDSGDDQPQSS------EAKRTKFSNPAIPP--VIDLEKIKFDESSKLMTVTKVSLPEGSFKRVKPQYDEIHIPAPSKPVIDY--ELKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKWDITTRNSNNLAIVELVRLLIIDEIHLLHDDRGPVLESIVARTFWASKYGQEYPRIIGLSATLPNYEDVGRFLRV-PKEGLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQSNVQYYLSVLNQQLPIESQFVSKLVDNLNAEVVAGNIKCRNDAVNWLAYTYLYVRMLASPMLYKVP--DISSDGQLKKFRESLVHSALCILKEQELVLYDAENDVIEATDLGNIASSFYINHASMDVYNRELDEHTTQIDLFRIFSMSEEFKYVSVRYEEKRELKQLLEKAPIPIREDIDDPLAKVNVLLQSYFSQLKFEGFALNSDIVFIHQNAGRLLRAMFEICLKRGWGHPTRMLLNLCKSATTKMWPTNCPLRQFKTCPVEVIKRLEASTVPWGDYLQLETPAEVGRAIRSEKYGKQVYDLLKRFPKMSVTCNAQPITRSVMRFNIEIIADWIWDMN---VHGSLEPFLLMLEDTDGDSILYYDVLFITPDIVGHEFTLSFTYELKQHNQNNLPPNFFLTLISENWWHSEFEIPVSFNGFKLPKKFPPPTPLLENISISTSELGNDDFS--EVFEFKTFNKIQSQVFESLYNSNDSVFVGSGKGTGKTAMAELALLNHWRQN-KGRAVYINPSGEKIDFLLSDWNKRFSHLAGGKIINKLGNDPSLNLKLLAKSHVLLATPVQFELLSRRWRQRKNIQSLELMIYDDAHEISQGVYGAVYETLISRMIFIATQLEKKIRFVCLSNCLANARDFGEWAGMTKSNIYNFSPSERIEPLEINIQSFKDVEHISFNFSMLQMAFEASAAAAGNRNSSSVFLPSRKDCMEVASAFMKFSKA--IEWDMLNVEEEQIVPYIEKLTDGHLRAPLKHGVGILYKGMASNDERIVKRLYEYGAVSVLLISKD-CSAFACKTDEVIILGTNLYDGAEHKYMPYTINELLEMVGLASG-NDSMAGKVLILTSHNMKAYYKKFLIEPLPTESYLQYIIHDTLNNEIANSIIQSKQDCVDWFTYSYFYRRIHVNPSYYGVRDTSPHGISVFLSNLVETCLNDLVESSFIEIDDTEAEVTAEVNGGDDEATEIISTLSNGLIASHYGVSFFTIQSFVSSLSNTSTLKNMLYVLSTAVEFESVPLRKGDRALLVKLSKRLPLRFPEHT----SSGSVSFKVFLLLQAYFSRLELPVDFQNDLKDILEKVVPLINVVVDILSANGYLN-ATTAMDLAQMLIQGVWDVDNPLRQIPHFNNKILEKCKEINVETVYDIMALEDEERDEILTLTDSQLAQVAAFVNNYPNVELTYSLNNSDSLISGVKQKITIQLTRDVEPENLQVTSEKYPFDKLESWWLVLGEVSKKELYAIKKVTLNKETQQYELEFDTPTSGKHNLTIWCVCDSYLDADKELSFEINVK-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 743, "similar_positions": 774, "identity": "33.65%" }, { "cls_id": "homologset.agr.SGD:S000000975", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTL1-1", "uniprot_id": "E9PTL1_RAT", "id": "E9PTL1-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSARKRGRLP-LEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHGGSILLITGPPGCGKTTTIKILSKELGIQVQEWVNP-ILQDFQKDD-YKELFNSESNFSVIPYQSQIAVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRD-ANALHEILRKYVHIGR---CPLVFIVSDSVS-GDSNHR------------LLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKASLELLCQGCSGDIRSAINSLQFSSSKG---ENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFFNLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAHCQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQG---QPAQTADPETWSLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXW6-1", "uniprot_id": "RAD17_MOUSE", "id": "Q6NXW6-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSETFLRPKVSSTKVTDWVAPAFDDFEANTAITTITASSLTFSNSSHRRKYLPSTLESNRLSARKRGRLS-LEQTHGLETSRERLSDNEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLEVKPKQGGSVLLITGPPGCGKTTTIKILSKELGIQVQEWVNP-ILPDFQKDD-YKELLSLESNFSVVPYQSQIAVFNDFLLRATKYSKLQMLGDDLTTDKKIILVEELPNQFYRD-PNALHEILRKHVQIGR---CPLVFIVSDSVS-GDNNQR------------LLFPRNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKIIVPNKTSLELLCQGCSGDIRSAINSLQFSSSKG---ENSSWSKKKRMSLKSDAAISKSKQKKKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELDSPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGDFFNLYLHQNYIDFFAEVDDLVPASEFLSFADILGGDWNTRSLLREYSTSVATRGVMHSNKARGFAHCQGG-SSFRPLHKPQWFLIQKKYRENCLAAKALFVDFCLPALCLQTQLLPYLALLTIPMRNKAQISFIQDVGRLPLKRSFGRLKMEALTDRELGLIDPDSGDESPHSGGQPAQEAPGEPAQAAQNADPETWSLPLSQNSGSDLPASQPQPFSSKVDMEEEEEEEEDIIIEDYDSEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75943-1", "uniprot_id": "RAD17_HUMAN", "id": "O75943-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSKTFLRPKVSSTKVTDWVDPSFDDFLECSGVSTITATSLGVNNSSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP-VLPDFQKDD-FKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRD-SHTLHEVLRKYVRIGR---CPLIFIISDSLS-GDNNQR------------LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAINSLQFSSSKG---ENNLRPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKILYCKRASLTELDSPRLPSHLSEYERDTLLVEPEEVVEMSHMPGDLFNLYLHQNYIDFFMEIDDIVRASEFLSFADILSGDWNTRSLLREYSTSIATRGVMHSNKARGYAHCQGGGSSFRPLHKPQWFLINKKYRENCLAAKALFPDFCLPALCLQTQLLPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSAEESLG---EPTQATVPETWSLPLSQNSASELPASQPQPFSAQGDMEEN------IIIEDYESDGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGQ6-1", "uniprot_id": "A2BGQ6_DANRE", "id": "A2BGQ6-1", "name": "", "aln": "--MMSKLSLGGKQSSGKINNWVEPSFGELLG------------GVSRSLKKGPLSGESKTAEKKSRKRKVDPYVSDNQITVSSEANNPDQDEPWVDIHAPQSQAELAVHKKKVEEVESWLRVHLD--KSKKGGAILLLTGPSGCGKTATVQVLAKELGFQVQEWSNPSTTSQYKTEDLFTQSFDPDSRFNRFHGSSQTGLFQEFLLRANKYSRLRMSGETWTEDRKIILIEEFPNQFYRQ-PGCLHDILRQFIKCGR---CPLVLIVSDSLS-GDKNSR------------LLF-KDVLQELGIHNISFNPVAPTSMMKVLSRIVTIEAVKSSGRISVPDKAALDLLCSGSSGDIRSAINSLQFSSFTDNSLERRLWASKKGKSSSAKPAVKAKGRSKSSKSKDMQDESPAIGGKDASLFLFRALGKILYCKRESYEGTQAPKLPPHLTDHQRDRLLVDPELVIERSHMSGEFFNLYLHQNYPDFFSDVEDIAQASEYLSDADFLTAEWSSRSTMLEYGSSVATRGLMHSNSSRAQANSQST-AGFKPLHKPHWLHINKTYRENYQTAQSLFLSFCLTPVSLLTEMVPYLAKLTNPMRNQAQIAFIQNFGHLSQKRVTGRLRLEALGDKDPGILDADSENE---DSCAAQSLDPG----TTQANATTESNLPNSQDPSGELSASQPQPTSTEALLDEE-----DLLIEEYDSD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96532-1", "uniprot_id": "O96532_DROME", "id": "O96532-1", "name": "", "aln": "MSVRKKTWVRCAFSEMNLTTSPAPSESTPAKRTR-----SASNVSSSRVSRSRTPSINTKPIQIPDVDSVDLTAMDDDQDADITVPPPEVKENWMESFEPATSDDLAVHPKKVGELRDWLR-HCEAVRKKFPAQMCLLTGPTGAGKTTTLRVLAKEFGYQLQEWINPIDCEVVNTLG--------DQTTGASYVGSHLEAFKSFLLRASRYKSLLDS-----QNKRLLLVEDFPNVLLSDKEVNFEELLEEYTAYGK---SPLVFIVADAKSRGLNISY------------RLFPDQLKAKHRIEHISFNAIASTIMQKSMKTFCSVMQ-QNKATYKVPSTAVVDSIVVGAQGDIRNALINLHLSSLKG---------VSSMPTKQLNVSVSAKGRKKKMQSTLKS------IGRDESITLMHALGRVLNPKFN-----------------EDKTMLHSPEEITEAFNTEPRNFVNFVYANYLPHFKEIDDVVTAINDLGLSDCMLNEYRD-DNLSVMGLNVAIRGVMMSNTCPVSG----------------WMPVRGPKRIN-----------------------------------------IQPQATLAEQRLVG-------------------------------VGYAG----IARTLYATEYSSLVKLIAGKPVDTTSSQSTDSKQDF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32641-1", "uniprot_id": "RAD24_YEAST", "id": "P32641-1", "name": "Checkpoint protein RAD24", "aln": "------------MDSTNLNKRPLLQYS---------------LSSLGSQITKWSSSRPTSPVRKARSTENDFLSKQDTSSILPSIND-DGGEQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHR---ILLLSGPSGCSKSTVIKELSKILVPKYRQNSNGTSFRSTPNEH-------KVTEFRGDCIVNDLPQMESFSEFLKGARYLVMS------NLSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITECEIPENDNNYRKFGIDYTFSAETIMNKEILMHPRLKRIKFNPINSTLLKKHLKFICVQNMKMLKEKNKWNKRQEVIDYIAQETGDIRSAITTLQFWATSSGSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMINNLFENSNNLLSKEDFKLGILENYNTFNKGEFSISDASSIVDCLS--ECDNMNGLPESNEYGLREVRKTFRNISKQGHNHGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNAVHSFRNITLEFGYYAPLIRKCQSYKKKYILYYLKNLPSGSSGPKQTMDKFSDIMKVENGIDVVDRIGGPIEALSVEDGLAPLMDNDSNNCDHLEDQKKERDRRLRMLIDQYERNVMMANDDLEDEETSFNDDPIVD---SDSDNSNNIGNETFGRSDEDESLCEILSQRQPRKAPVISESLSDSDLEIL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. ::. . . : . :: . * * : . * ::*:* :*: ::. * : : *::**.*..*::.:: *:* : :: * . .. ::.* . * : ::*:*::** : : :.::: : .. **:: :::. . :: :: . : .*.**.: .* : * :. : . : ****.*: .*:: : .. . : .. . . . . : * . : : . : ** . * .: . . : . . :: . . . : . : : : * :: . : . : .: : . ", "identical_positions": 39, "similar_positions": 135, "identity": "5.45%" }, { "cls_id": "homologset.agr.SGD:S000000976", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLZ1-1", "uniprot_id": "GLRX3_RAT", "id": "Q9JLZ1-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAAEAAVAVVEVGSARQFEELLRL-KTKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGSFPPSTNEHVKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQM9-1", "uniprot_id": "GLRX3_MOUSE", "id": "Q9CQM9-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAGEAAVAVVEVGSAQQFEELLRL-KTKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGAFPPSTNEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76003-1", "uniprot_id": "GLRX3_HUMAN", "id": "O76003-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEA--AVAAVEEVGSAGQFEELLRL-KAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL--PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWPTYPQLYVKGELVGGLDIVKELKENGE--LLPILRGEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ54-1", "uniprot_id": "GLRX3_DANRE", "id": "Q5XJ54-1", "name": "Glutaredoxin 3", "aln": "MAN-----------FTDAASLQQFDELLKN-NSKSLTVVHFHAPWAPQCSQMNDVMAELAKEH--KHTMFVKLEAEAVPEVSEKYEITSVPTFLFFKGGEKIDRLDGAHAPELTNKVQRLGSGGGGAVGAGDVPKEDLNQRLKRLINAAPCMLFMKGSPQEPRCGFSRQIIQILKDHNVQYSSFDILSDEEVRQGLKTYSNWPTYPQVYVSGELIGGLDIVKELVESGELENTFPKTVSLENRLKSLINKSPVMLFMKGNKEAAKCGFSRQILEIMNNTGVEYDTFDILEDEEVRQGLKTYSNWPTFPQLYVKGDLIGGLDIVKELLEGGE--LVSVLKGEN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ6-1", "uniprot_id": "Q9VJZ6_DROME", "id": "Q9VJZ6-1", "name": "", "aln": "------------MPVVNVSAAEEYQKYIN---ADKTTVALFAAEWAEQCGQVKDALEELAKITG-EKLQFISLNAEQFPEISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAAATGQT----------------------------------------------------------------------------------------------------------LEERLKALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYETFDILGDEEVRQGLKTYSDWPTYPQVYVKGELIGGLDIIKELLANNE--LESTLKG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32642-1", "uniprot_id": "GLRX4_YEAST", "id": "P32642-1", "name": "Monothiol glutaredoxin-4", "aln": "------------MTVVEIKSQDQFTQLTTTNAANKLIVLYFKAQWADPCKTMSQVLEAVSEKVRQEDVRFLSIDADEHPEISDLFEIAAVPYFVFIQNGTIVKEISAADPKEFVKSLEILSNASASLANNAKGPKSTSD-----------------------------------------------------------------------------------EESSGSSDDEEDETEEEINARLVKLVQAAPVMLFMKGSPSEPKCGFSRQLVGILREHQIRFGFFDILRDENVRQSLKKFSDWPTFPQLYINGEFQGGLDIIKESIEEDPEYFQHALQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: : :.. * * * ** * :.:.: ::: . *:.::*: **:* .:* :** .:*: . :..:.... : . : . .. . :: ** * : :.:*:****. . .:****:*:: *:.. : : **** **:***.** :*:***:**:*:.*:: *****:** . : *: ", "identical_positions": 56, "similar_positions": 79, "identity": "16.37%" }, { "cls_id": "homologset.agr.SGD:S000000977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1LYP9-1", "uniprot_id": "Q1LYP9_DANRE", "id": "Q1LYP9-1", "name": "", "aln": "MAVRLFEGKEHANSYWKYRISPSEELIGKVLQFHRNNEYSSNGLAVDVGCGSGQGTLLLAPHFT---RVVGTDISPAQLEMGRKHVN-----IPNVSFRESPAEELPFE------DGSVDLVTAMSAFHWFDHSRFLQEADRVLKPHGCLALLNYT------------LDMELTYGNCSEALNLICNEFYAALHPLRDPHLGPSSFELYKRTYDSLQYP------VKEWHDLFWVKKAVPLSGYIGMVKSFSTFQTLLKTDPEEARR--LSQGIEDRLKRAMDVTSSETEVIMGVKYFYFLAQKPAND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32643-1", "uniprot_id": "TMT1_YEAST", "id": "P32643-1", "name": "Trans-aconitate 3-methyltransferase", "aln": "-MSTFSASDFNSERYSSSRPSYPSDFYKMIDEYHDGE----RKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPDTYKNVSFKISSSDDFKFLGADSVDKQKIDMITAVECAHWFDFEKFQRSAYANLRKDGTIAIWGYADPIFPDYPEFDDLMIEVPYGKQGLGPYWEQPGRSRLRNMLKDSHLDPELFHDIQVSYFCAEDVRDKVKLHQHTKKPLLIRKQVTLVEFADYVRTWSAYHQWKQDPKNKDKEDVADWFIKESLRRRPELS-TNTKIEVVWNTFYKLGKRV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. ::: * . * * ..:: : ::* .: . * ******.* .** :* .:. :::*:*:*.: :: .. : ****: *.:::: * . .:*::**:.. ****..:* :.* *: .* :*: .*: * :*:.**: . . : *:*.**.*. *. : :* . : :. :. : ::* *.* : . *:::*::: : :: :. . *:: *:* ::: ::*:: : : ** *.:: ", "identical_positions": 60, "similar_positions": 113, "identity": "19.48%" }, { "cls_id": "homologset.agr.SGD:S000000978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QAM5-1", "uniprot_id": "HELZ2_MOUSE", "id": "E9QAM5-1", "name": "3'-5' exoribonuclease HELZ2", "aln": "------MASVGCSLRSASTSATNGPSLAGLCAKVDLYLGCSRCTQCLNESTYILREVEHTCPREILLARFKQAAESKIWRKVGRR----------PSFPTPMRYQVCHYYRPGLGCRRHWNRCTFARSPEEALVWTFELKNNLPRLKLKEAVQGTRAPDRLQTPADTIRAEFGGHFQLLCAICFTCCPPCLCPVDPRGHCPKHQICPTLLIHVIVEG-LKRQFVEVRPLPQRRHPLNYCMYVGRGVPCRHGASRCEYAHSAVEMAVWKAEQLDGLQRGDLLTYPLFGENKWKASPNPNPPVTKLYC--HACLVTCNS-QEAFENHCSSLEHAQMVAFDQAVPWKHRAPPMGLSKFDL---CPRPDLCEHGEVCIKAHSKQELQEWVQRAQDMELREQAAWQDGLVPYQARLLAEYQRSSKEVSVMAETIRGVSVTCHPPPVHQAQEK-IQHQWVFTIHSEDPLLHVALLNQEPGAAFSLVAPSLPPHQLYAQGKHFCVQSSPAQYKVGVLVQAVAFGSFEQWVVFDFGRRPVLLQKLKLQLGQTHSQGLNGKPAPSHPQELECWHTGNRHVVLEVDWTPEQEALMAKYKLPSLALEFNQIVPDWGPISRSNYRQRMHKFLYEEEA-----AQQQLVAKLAMKGQVSLKTALETPALGMLFAPPGALYAKVPFHSSLLPDTDQGFLLSRAVSTALVAPVPAPNSTVYQVRLEARASSDHALWLLLPARCCMALGLQAQDSPILEVQFQIDPMTFRFWHQAVDALLEEHLVVPDLPACTLPH-PWPTPPSFRGNHKQKLAVGLIAGRR--PEGTKHIPPLLIYGPFGTGKTYTLAMAALEVVQ-QPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATPLRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQARELQ--VPAGFFSHIFI-----------DEAAQMLECEALIPLSYALSLTR--VVLAGDHMQVT----------PRLFS-VPRDKSARHTLLHRLFLY----YQQEA--HKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVP-----------RHPQHYPLMFCHVAGSPEQ-DMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPRE--QRHICAVSHGAQVSALRQELRRR-------NLGEVSVGSFEILPGREFRVVVLSSVHNR-NSLLSPGAPTSEFFTEPRVLNTVMTRAQSQLVAVGDAVALCSSGACRNLWRSFIRECIEHHSAFPEELSLEQIEQGVAQRQNWASLTLKARGP-------------ETEQKSMAQGPQRLIAEGTMVTVKAETRAEAAAKAQTAAVAAEDTASGNSASRDAAAEVSTLEGGMS--EEDSESDFWPSDWELNADDAILKELLDESQQVTVTVREDGLLDTVVCS-APQKAREYTNLPSSVLWKFLRSNSKQFRRC-SFLQETFERALATPLDDMASSPIQVRGRLNCGMAFTGDEVLVQILGPAGDDRCVPGSLQGRVMGVLKRRRHELAFVCRMDEWDPRIMIPINGSVTKIFV--AEMKDPQQVPIHRLIQGQVQRVRHETLKPEDRSTRLFWVRIVLWRERFYYPLGIVLEVLPKAITWEQGLYILDLEHGLKAHTPDPASVSKALQRYRSELNTAAGHREDYRHFLTFTVDPQGACNLDDALSVRDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAPNREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFAPSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACYFSWMLRRQRLSAACYYEPPDEDSVLGFRTAHI-MVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQPTPSRQQLDSVFKKYRGLVPLSLHLCHHSN--TDYTPNKQLHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQRRAYSLHLAIQLKSQPQNKLGFVVDVEMGARCFKVLFPINRETLPDPCPIHYHSLQLAEHPQELVSQTGVRLVWRRRMYSVQASKLPLPLLGTSLDPHTQTVDAALWMKLLMLLKEQRWPEIAALIQEQDKRFHPREKVKIHQSRCGHFVEVVYELGSGDTLQVQLGSSLQRGFLAPTLKLWTVVPGFSLCLEHMERPGDCFSSHVHQALQDQYLQVGEYSGAWGPRCALESLTNAVTENDSIVLHDVHISWDTS---QGQLQGTFQLEAAFLQEKCINIHFGCCYLCIRLEGLPLPLDSSLPGPSGLGPFLNIDPNTYTWVAHGLSGDWDHELAGGDWDQENVDDRQEAPKQVYFLIHHMTMEKVPEEVLRPSARFTVEVLSKQLPDLRKEEAVRQLKTASPLVISIALGLPIPEIRWPISGPRRLVSELRWPIPGPRRPVSEPHRPMSGPCGPISEPCRSIPEPCRGNWPRQHSFHKASTSRFLERQNYNIPAGHHKLNQSQDRAVRSALQKQFTVIQGPPGTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKPLRVYGEQAEATEFPLPGVSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLREGKIFSKEDLRVYRRVLGKARKHELERHSVILCTCSCAASKSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHRDAIMLDTQYRMHKDICSFPSVEFYGGKLKTWSDLRRLPSILGHTGKPSCSVIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQLTLDRTVDPKDIAVLTPYNAQAAAISRGLMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVSAEKVRVQRKSALSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYK8-1", "uniprot_id": "HELZ2_HUMAN", "id": "Q9BYK8-1", "name": "3'-5' exoribonuclease HELZ2", "aln": "------MAPPGSTLLPNSPAATRGPSLARLCALVDLCLGCSRCTQRLNESTYVLRRVEHDCSREILLARFKQATKSKVWRVVGCR----------PTFPRPLCYQVCHYYSPGLGCRRHRNRCTFARSREEALVWTFERQHNLQRLWLKAEVQGSGAQGGAGRAADAILTEFGGRFELLCSLCFRRCPPCICRVDPQGQCPEHGACPSLLAHVSAEGRRKQQFVVVRPRPRAGQPPAYCRFVGRGQPCWRGESRCQFAHSAVEMAVWEAEQLGGLQRGDLLTPPAP-DGDGRTAPLGQPPGAQLYC--PACLVTCHS-QEAFENHCASSEHAQMVAFDQALPWEHRSPPPGLSKFEL---CPKPDLCEYGDACTKAHSAQELQEWVRRTQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPLMYQAQERKTQYSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTADFQVGVRVQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRHVVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEA-----AQQQLVAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVPAPDNTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDTLPEEQLVVPDLPTCALPR-PWSVPPLRRGNRKQELAVALIAGWG--PGDGRRVPPLLIYGPFGTGKTYTLAMASLEVIR-RPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELR--VPVGFFSHILI-----------DEAAQMLECEALTPLAYASHGTR--LVLAGDHMQVT----------PRLFS-VARARAAEHTLLHRLFLC----YQQET--HEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVP-----------PHPRHYPLMFCHVAGSPDR-DMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGRE--QRCICVVSHGAQVSALRQELRRR-------DLGQVSVGSFEILPGRQFRVVVLSTVHTC-QSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHC-SFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLS---GDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFV--AELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHI-MVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQT---------QDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP-----------------------------------------LCRVIPS------------------RFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRR-MELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFP-QAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXK5-1", "uniprot_id": "M10B2_DANRE", "id": "Q1LXK5-1", "name": "Probable RNA helicase mov-10-B.2", "aln": "---------------------------------------MSRRNRNNYLSIAAVRTIGLDFIEMLEETNRRSISDRNTLTDIYN-----------TEFRDRDGGVKDPNFSRVLYALRNANKARLSRTGRVYFNTNVRTGLHDQWFRPRRRQQNQANATPGNVSS---VTPSS--------------DQGPS-CPESGVRARRKLVKYILQRLNTTD----------------------------------------------RSHFIADKWG-----------------VRVSSELYIEDGKIRI--SVDEAEVYE-LKLFVENTG----------QEAVYFTYYTALCWLQYFTL---EDSRKVTRNNPLRLEPREKYEVIVRFK-------------SSHVGVYSATLAFEFKKNTQPTTRSFHIVR---------------------------------FIEAEYRSKLAALLGPTEPYKP-------------------------------------------LRLNISEPENCIIDEGFPPDGYLQNFLVNVLPLGKYIPPPDTTILAELLKEDCSSRIFRGKLKDLQSLLQS------PLTFDNYAERFDLLLYLEEC-----QMHVDIKRYNKD-SVTLHRDRDKRLMGLNLPGVSENRPSVLRGDHLLLTKSE---------EVTFSNVTKYKGYVHRVELDQVKLG-------LSKRFLKDV---YIDKMKFRVEFTVNRIPVRLQHRAVHMAVQHNLKDVLFPMASRSLNPVSPPALRLFDRKLEYNFQQYSAVCNIVAGTSKPAPYLVFGPPGTGKTVTIVEAIKQVEKNIPDAYILACAPSNSAADQLC----EKLITSEHVDAHKIYRLYASSRNQKDIPKILKDNCNVDEEMIDFPCKEDLMSYKILICTLVTAGRLVTGGFSEDHFTHNFV-----------DEAGHAVESETIISVAGLLNAEKGQLVLAGDPKQLG----------PILRSPLAINHGLDVSLLERLMTQND-LYKRGD--VEFDNRYVSKLIMNYRSHPYILEVPNRLFYDGELKACADEISSNQYCMWEH----LPSKGFPVIFHGVPGKDER-ESNSPSFFNIYEINILVDYLKKLLLTQPKKGISRIFPKDIGIIAPYRKQVEKIKRAIDADKDFQDYMGIDNLKVGSVEEFQGQERKVIMVSTVRSSVKYISLDETFNIGFLKNEKRFNVAVTRAKSLLIMVGNPMILR----TDESWGRFIDFCLERGGYTGISITSVERIDDVESR---------------------------------------------LLALNIQDE---ETEESPVQRYVDPEFRNDY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LXK4-1", "uniprot_id": "M10B1_DANRE", "id": "Q1LXK4-1", "name": "Probable RNA helicase mov-10-B.1", "aln": "---------------------------------------MSRKYR-KKLSRDDIRAVGFDFIEFLDDRETRSTTDRNTLKEIYN-----------EQFRDRDG-VRDPNFSSVLFALTRSSRTRVTRS-EVFFDKKIRVRQNDQWSRPYRSQQNHATPHLNDAISRPSTTRVS--------------DPSSVPEPENRVIARRRLAKTIMRQGNSED----------------------------------------------MSVFFADKYG-----------------VRVSSELQIEDGKIHW--CVEGAEVHE-LKLFVENTG----------QEAILFTCFSALHYLQYFTL---DDSQRVRKDNPHRLEPNETYEVILRFK-------------SDQIGVYPATLAFEFKENQD--TRPFHIVR---------------------------------FIEAQHRSELTAQLGPTEPFRP-------------------------------------------KRLDTNQPMKWSIDEGFKPESSSQNFLKFVVPLDNYNCPSYTSALIEVLKGNRSS---GKQLQEHQLTLES------DLSFNNYMDRFDLLLYLEED-----QMRMDIKRYNKK-DVSMVRDRDKKLLVLELPGVSENRPSVLRGDHLLLTKSE---------ELQNSNVTKYKGYVHRVELDQVKLG-------FSKRLLER----FIDNMKFSVEFTINRLPLRLQHRAVHMVVQHHLKDVLFPVASRRLNPVSPSALRLFDQKLEKNPEQKTAVCNIVAGTSKPAPYLVFGPPGTGKTVTIVEAIKQVEKNTGGARILACAPSNSAADQLG----EKLITSQHVDARNIYRIYASSRNPKEIPKVLENNSNVEGENIIFPCKEDLMPYKIVVCTLVTAGRLVSGGFPVGHFSHIFV-----------DEAGHAVEPEIVISVAGLLNAETGQLVLAGDPKQLG----------PILRSPFAIKYGLGLSLLERLMTQNE-LYQKGD--TGFDNRYVTKLLQNYRSHPSILKVPNELFYDNELKACADEISSRQYCTWEH----LPKRGFPVIFHGVVGKDER-ESTSPSFFNTSEIDKIMDYLKKLLLTQAKKGIAKISPKDIGIIAPYRKQVEKIRQAIKIHRELKSLSGIEELKVGSVEEFQGQERKVIIVSTVRSSKEHIILDDKFNIGFLKNEKRFNVAVTRAKALLIMVGNPIILR----TDEIWGRFMNYCIQERGYTGYDITHLEETDVIAER---------------------------------------------LLSLNIRQEITVETEESVVQQFLSPPWRHEH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32644-1", "uniprot_id": "ECM32_YEAST", "id": "P32644-1", "name": "Putative ATP-dependent RNA helicase ECM32", "aln": "MDFQCRTCSQAYDAEQMMKHLSSTRHKTVFDTSNDEDICCEECQDKNIHQLQIIRFGGEDMVLLCNSCFRKEYSETERPSTSYSLQNGSILKFWEKYVKVRECCCDECGEESNLNANRNGEVLCDKCLPKSNRAKDFVSEKSGRFLYIYLGLNETQNSTRKPRKKGGRRVGRGKK------------GRKGAKIKKEKKETFEAKISRIAYEVKKEN-------------------------------------------STIQSSSSSNLRNFKGFKAVESDPVVAAKVSKSETSRSNPGPSNRN--KGKGNKANH-KKNSGNGIG----------KEKERKTNIRNNVRNSQPIP---EDRKNTNSHVTTNSGGKGKNESVDKHQLPQPKALNGNGSGSTNTTGLKKGKKDHAGQKTKGNDKTGNKNP---------------------------------REAKLNSAGRKNALGKKSNNQPNKG-----------------------------------TSRWTIGSDTESSREPSISPNENTTSITKSRNRNKKASKPTLNEKSKTTTMPKKLETKNQEKNNGKTKDGKLIYEEGEPLTRYNTFKSTLSYPDLNTYLNDYSFALFLEQKLENEFVQNFNILWPRNEKDTAFIINVEKNNNSELEKLLPANLLALGRPAFN-----ERQPFFFCTQDEQKVWYIFIKELSIQ--------RGKYVLLVELFSWNNLSLPTKNGSSQFKLLPTSAQTSRILFAMTRITNPKFIDLLLGQKPIKEIYFDNRLKFSSDKLNRSQKTAVEHVLNNSITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAIDNIA-----EKIMENRPQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVANKTRRGEMISKSEDTKFYKEKNRVTNKVV-----------SQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLPGIRNFVFVGDEKQLSSFSNIPQLETSLFERVL--SNGTYKNPLMLDTQYRMHPKISEFPIKKIYNGELKDGVTDEQKAWPGVQHP----LFFYQCDLGPESRVRSTQR-DIVGFTYENKHECVEIVKIIQILMLD------KKVPLEEIGVITPYSAQRDLLSDILTKN-----------VVINPKQISMQQEYDEIELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNN----TENKIGFLRDKRRLNVALTRAKHGLIVVGNKNVLR---------------------------------------------KGDPLWKDYITYLEEQEVIFTDLTAY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "B7Z0D7-1", "uniprot_id": "B7Z0D7_DROME", "id": "B7Z0D7-1", "name": "", "aln": "------------MSSVWYLEHVTTGARLILHNGTNLMGRHSRCRIILGGQYQFVSREHANIIVSEKGVEVESLNPLNGLFINGGKLG-----DKINRLAVAEGSTISLGVTGVNLNEITGIHAIFILKKKEPVVEEIVLSSDDDDTTPLPAVRCPTGTQPTEFNLKQQIPNFGGKQD----------PGQEEEVLPSSSNLHLPKLTEVKQEIVKHT-------------------------------------------SEEIQNIFGEPSDAILNSVLELNPYLYNKLTNKTANNEITRKKIHDGDCIELDTDTD-RRSISEAQKAEDPSAEREVDDEEEYDESFAMSQAVIREM---KAEMHVSDGEEDFLLTNGMGNLPEGSPSNQAYDDIVYVSDSDDDELYDKVADWSKLLSQKVVPDVIEMSQTYP------------------------------LENEHKDSDSDLDIGAKKPKRTLRIS---------------------------------------SSSDEDSADEVIVHQTKQKGRRSKSKSPNDHVVRQADSTTPDLPAVRKLSVSSIDSVYENKQTKLNSKLKSCLKSPTKTSVDNMENMTETKSCSNRQREQIVASRNEPTNICPQKIETNKTSTRKRFVSTTSRDELSTTSKEIKDAPKNNVEPPKKMLRSRSKSCYIDRPVELDEHITKNEVPLKKKYESVD----NSKEELIVTLEAPAMLTTPTKSKTQCVKKKATQTRGRRKTIHSRDEIRSLTAEAEENKKISPAKQTNEEIPIPTKSPLKRNARLLNRSKSCYMDRLVISETEDPAKKVIKDISPTKSDTTDNVLNFVDVRQTRGPSVIEAP---SLPKNRGKLRGVSAEVKVKDKVLDRQRFIDYQAEMNAKWKQKPKDKKKEDEKLKECRREALKKLSEKPKENSHRSTTNK-----------RKNPTSVPTVQNTNRGGFLTKGVDGPAPKLAKTDNAK---------PPPKKPVPKQPPAIETFSQQLQAADKAVLHPQPQCSRPVERKEAELARNQRTCNKVTFAEMELYHQKAEDSKKLQKKLRKVHFNDD----VKVHCIERVKGASSKVQGRKECIKLRLSSYRERREWIRRENKPVNDIRQHSRSILKWANQWLKHGSVDAVAEQDVLMPIP-------PEFDSFKNYREIFVPLMKLELLSTIERDYKINNKNTFSVSLINVETQDMCYRLVTRVNSKPFGKFVLYTLYCCGMLKETFANLLELKFVSGNVFDLTFEILKQDISEEKLKN-------------------------------------------IKQLTARPVVDSLRVELGALSAVHQLRSSPLCRRILKPTQTVNEVSLPKQPFTFKGCHKLNEHQENIVLHTYQRIIDDLQPSLTLIQGPPGTGKSRVISELCLQTLYGNAAKTLDRKILICAHSNTAVD-HIVGLLGS--------------------------------------------------VLRVMNRDQFHLLRFGMHEKMSHYSRPFSLEAHFNKAKEQK--LQRVSKENAEILKKQHNDLKDEIQQLKEKTNLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCVKLANYVDFFDICIVDEATQCTEPWTLLPMRFGLTHMVLVGDMQQLP-------AVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLINAECTARFASPLIPYCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMDKHMPSKRFSYGLISPYQNQCYALSQVIPSHMNITPQ-TVDSYQGLEKDVIIISNARTRGCGFLTNYQRLNVALTRPRRCLVICG----------------------NFEDLKSVEMWRNLLDDARKRKVYFNLDRDDVNDLDRSLIKKMMVNTINLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0VGT4-1", "uniprot_id": "ZGRF1_MOUSE", "id": "Q0VGT4-1", "name": "5'-3' DNA helicase ZGRF1", "aln": "------MECQEFIVLYTHQKMKKSKVWQDGVLKITHLGNKAILYDDKGACLESLFLKCLEVKPGDDLESERYLITVEEAKAVGSRAVE----PDGSREALESGSRTLVSSSRSLGCQPSGLKRKATGFQRPYKMPKKVTITENSEPAASLGDENPGPPGPRLLPTFSSTLPLFPTVGQKDLTPVSTDNQSPITFSNRERSDTPLSLPSSYFKINTNTLGKEDKLCFPVSSETKHSDSLLASEPMR---------------RNGLDSHCPGVSQNVRSKAQILALLKSSSTNRKDLHGEIPGHFPKIEPQGCLNIISKPEEDYAETQSIGNLRCEQQSENPTRTTSRWARYLPSQRSPPCSAADENDTEDKPEAQEDVNIFNLSELLQKKSELFETCSKKGELHSEDKPVDNTCQYWNQEDNLAPSFCKNSSVLVSCSSKENASLLSESDIQYSSKVPVNQHEKVWTREGSQGADADAALEPEYRPVSPLPEIG----------------------------HKQTEVEASLSTSSRISDDIADMGSKSNADREDLKTVHKAVQPFLEVSFNLSNFETSDTDEASQEDSRLSQDSERWEKEAVLTDDSCVQKSCEDIGCREIVGKLPLLSSTDDEPKEALPADGTLLSEFCDRTCVGFNSGPHGDVKTGKALEGQCHSDTGSSLDSSLEWSEDVAGDSREDASQSIQGNAINCGGVSPSKK---PRGVNRSLYSPYLLTAVTDPAPENSDLLSEARKSPAIEVSRALLECPCEHRASQQPVEFQGHQVKGSATSGVMVRGHSLQRGCTQFPDSIDYENFLTDTCVWTPGLPSTYGQTDFLQVISPEQKIPALSPAPTFSFNTRNEDTVLELSEESLKTRTLPGLKTIGFQDSKNLQRFPFLSGASAPFATLPADDGPAVLDPCSFMIDDDAREPSGSSMLNLCEESGLSFDLGLEGQGGTPGGVSLLPKSSTQSKWLKYQNPPQCNSTAPNRLASEVTEGLFAEAVSGLHFSHTSESESSVDPVRLQMIKGLLHQQQQDLVSRKQAFSLTLNQTCKTQEHETVLGSSASKNCRAKDLQEINNSDLCFPNGQKIISAYLPQRQVHIPAVFQSPAHYRQVFTASIIEHLNILLFELAQRLYKALSKVDISFYTSSKGETMRSGKNNSPSCHHNQPAKLVMVKKEGPNKGRLFYTCDKSKDNQCKFFKWLEEVTPGQLPQNTSQSTMVFNDIKSIGSYLRSQKVPVYEECQLLLRRGFDFQRKQCGKLKKLTTVNPDFYSETKSKIYLKLSRRESSS------------------------------------------VYSKGDLWVISKTLDFELDTFIACSAFFGPSSVNEVELLPLKGYFPSNWPTNITVHALLVCNASTELTTLQNIQDYFNPAALPLMPYLLAMSQSATVSSKNISKRKFIPPAITSIKTKTELHLGATLQLARELINVHRLNKDQATALIQIAQMMASQGSDEDALEPFGHSLPITVIHGVFGAGKSYLLAVVILFLVELFEKCDSGTVGNARPWKVLVSSSTNVAVDRVLLGLLSLGFEKFIRVGSVRKIAKPVLPYSLHAGSDNESEQLKELNALLKEELTPIERVYVRKSIEQHKLGTNRVLLKQVRVVGVTCAACAFPCLNDLKFPVVVLDECSQMTEPASLLPIARFQCEKLILVGD-------------PKQLPPTIQGSDAAHENGLEQTLFDRLCLMGHKPVLLRTQYRCHPAISAIANDLFYEGSLVNGISERERSPVLEWLPTLCFYNVTGAEQVERENSFVNVAEATFTLKLIQSLMASGVESCMIGVITLYKSQMYKICNLLSAVDVGHPDVKAVQVSTVDAFQGAEKEITILSCVRTRQVGFIDSEKRMNVALTRGRRHLLIVG----------------------SLSCLRKNRLWGRVIQHCEGREDGLQHASQCEPQLDHLLKDYLEKQAEEKQKKKEKEKSKDKSH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . . . . : .: : . . . . . . : . : : . . . . : : . . . . : : . : : . . . . . . . .: . : : . . : . . . . : : : ", "identical_positions": 0, "similar_positions": 59, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000000979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62258-1", "uniprot_id": "1433E_HUMAN", "id": "P62258-1", "name": "14-3-3 protein epsilon", "aln": "-MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62259-1", "uniprot_id": "1433E_MOUSE", "id": "P62259-1", "name": "14-3-3 protein epsilon", "aln": "-MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62260-1", "uniprot_id": "1433E_RAT", "id": "P62260-1", "name": "14-3-3 protein epsilon", "aln": "-MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P92177-3", "uniprot_id": "1433E_DROME", "id": "P92177-3", "name": "14-3-3 protein epsilon", "aln": "-MTERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIEQKEENKG-AEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYLAEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDGEPKEQIQDVEDQDVS---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29311-1", "uniprot_id": "BMH1_YEAST", "id": "P29311-1", "name": "Protein BMH1", "aln": "MSTSREDSVYLAKLAEQAERYEEMVENMKTVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETELTKISDDILSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMSES------GQAEDQQQQQQHQQQQPPAAAEGEAPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**: ** **********:**** **.**. . **:************************::*******.* .*.::::* ** :*.** *. ***.**:.****.*.:*********************::*. *:.*:: ** ***:**:** .:********************** ****:**:*** **************************************. . *: : :: *: :::: ", "identical_positions": 178, "similar_positions": 49, "identity": "65.2%" }, { "cls_id": "homologset.agr.SGD:S000000980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26284-1", "uniprot_id": "ODPA_RAT", "id": "P26284-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial", "aln": "-------------MRKMLAA----------------------------------------------VSRVLAGAAQKPASRVLVASRNFANDATFEIKK--CDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFNRGHAVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADP--EPPLEELGYHIYSSDPP-FEVRG-------------------------------------ANQWIKFKSVS---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35486-1", "uniprot_id": "ODPA_MOUSE", "id": "P35486-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial", "aln": "-------------MRKMLAA----------------------------------------------VSRVLAGSAQKPASRVLVASRNFANDATFEIKK--CDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADP--EPPLEELGYHIYSSDPP-FEVRG-------------------------------------ANQWIKFKSVS---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08559-1", "uniprot_id": "ODPA_HUMAN", "id": "P08559-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial", "aln": "-------------MRKMLAA----------------------------------------------VSRVLSGASQKPASRVLVASRNFANDATFEIKK--CDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADP--EPPLEELGYHIYSSDPP-FEVRG-------------------------------------ANQWIKFKSVS---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29803-1", "uniprot_id": "ODPAT_HUMAN", "id": "P29803-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial", "aln": "---------------MLAAF----------------------------------------------ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK--CDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDP--EPHLEELGHHIYSSDSS-FEVRG-------------------------------------ANPWIKFKSVS---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35487-1", "uniprot_id": "ODPAT_MOUSE", "id": "P35487-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial", "aln": "------------MRKMLTAV----------------------------------------------LSHVFSGMVQKPALRGLLSSLKFSNDATCDIKK--CDLYRLEEGPPTSTVLTRAEALKYYRTMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYRAHGFCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGKNFYGGNGIVGAQVPLGAGVAFACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLYGMGTSNERSAASTDYHKKGFIIPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELKEIDADVKKEVEDAAQFATTDP--EPAVEDIANYLYHQDPP-FEVRG-------------------------------------AHKWLKYKSHS---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06437-1", "uniprot_id": "ODPAT_RAT", "id": "Q06437-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial", "aln": "------------MRKMLATV----------------------------------------------LSQVFSGMVQKPALRGLLSSLKFSNDATCDIKK--CDLYLLEQGPPTSTVLTREEALKYYRNMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACNVGLEAGINPTDHIITSYRAHGLCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVALACKYLKNGQICLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNRYGMGTAIERSAASTDYHKKGFVIPGLRVNGMDILSVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRTREEVQNVRSKSDPIMLLRERMISNNLSSVEELKEIDADVKKEVEEAAQFATTDP--EPPLEDLANYLYHQNPP-FEVRG-------------------------------------AHKWLKFKSVS---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KVX1-1", "uniprot_id": "Q7KVX1_DROME", "id": "Q7KVX1-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha", "aln": "------------MLRTLSRVSELPIIVKQLQKRCHNNNNNNIIISGCRILSNNNNNSSIDIIRNGRYSSSFFGLFQNAAQAGVSKTNNYATEATVQVNRP-FKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNT-HGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDA--ELGVSHLWTDVYSNNLE-PKLRGTI--------------------------------AYDIDHIQERKGVNH--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4H4-1", "uniprot_id": "Q9W4H4_DROME", "id": "Q9W4H4-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha", "aln": "-------------MMKFSCVR---------------------------------------------VAMRCSGAHSILERNMLCRIIGRHKCSCLTLENT-FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAVAVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGCSRGKGGSMHMYSDKFYGGNGIVGAQVPLGAGIGLAHSYRKDNGVSVVLYGDGAANQGQIFESFNMAKLWCLPCIFVCENNHYGMGTHVKRASAMTEFYMRGQYIPGLWVDGNQVLAVRSATQFAVDHALK-HGPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQIIALCLADEEELKALDDKTRKQVDSICKKATTDR--EVELDELHTDIYAKNVD-GKIRGVSGFHLEHIKLAEVCFGKPKKTPASEINDVPVGAEIDVAKAKERKAKQDAKKAKEAKEPKGGDKKGADAKQPKGEGDDGDKKPKPAAQPPTKAPPAPKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16387-1", "uniprot_id": "ODPA_YEAST", "id": "P16387-1", "name": "Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial", "aln": "MLAASFKRQPSQLVRGLGAVLRTP----------------------------------------TRIGHVRTMATLKTTDKKAPEDIEGSDTVQIELPESSFESYMLEP-PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGFYGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNKYGMGTAASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRG-----------------------------------RIPEDTWDFKKQGFASRD----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . : *: * :: * * * :**:* .. ** : ******* **** **:: : * :*::** *. : * . ::*** * : * : *******:* *********** *****:.:* .* .. ...******:****: *::**: ** ** :* **** ***** .*::. .::. :* :**: *:* ::*.* .*:.** . :**:::* .**** ******** :**:*:*:: *.* *** :: : : *:* . ..:* ::. * : * :. : :* .. :** . * ", "identical_positions": 131, "similar_positions": 94, "identity": "24.17%" }, { "cls_id": "homologset.agr.SGD:S000000981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJ85-1", "uniprot_id": "D3ZJ85_RAT", "id": "D3ZJ85-1", "name": "Meiotic recombination protein", "aln": "MKEDQVVQEESGFQDEEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQ-ADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGDAKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14565-1", "uniprot_id": "DMC1_HUMAN", "id": "Q14565-1", "name": "Meiotic recombination protein DMC1 homolog", "aln": "MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQ-ADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61880-1", "uniprot_id": "DMC1_MOUSE", "id": "Q61880-1", "name": "Meiotic recombination protein DMC1 homolog", "aln": "MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQ-ADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25453-1", "uniprot_id": "DMC1_YEAST", "id": "P25453-1", "name": "Meiotic recombination protein DMC1", "aln": "-----MSVTGTEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGD--YRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::.: . : .:* **::*** :*::**** ** *:: : **** **::*****.**:******.*:*: **:.* : *: *: ::***:::*.:***** :*:***.***** ****:*******:*** * **: :****.****:*:::**: :::* :: * ** **** .*******:: :. :: . ::*:::***** ****:.*****:****** * * :*::::**:*****:***: :****: * ** :******:*****:*** ******: *:**: ***:***:*..:.* ** *:.:", "identical_positions": 176, "similar_positions": 96, "identity": "51.61%" }, { "cls_id": "homologset.agr.SGD:S000000984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQJ0-1", "uniprot_id": "THEM5_MOUSE", "id": "Q9CQJ0-1", "name": "Acyl-coenzyme A thioesterase THEM5", "aln": "MLRTSFQGVARLVRHKALYRSPCLLPRVHLASAFGSSTESLVARFCPEKTDLKDYALPNASWCSDMLSLYQEFLEKTK---------SGGWIKLPSFKSNR----DHIQGLKLPFGLETASDKQDWRLFTRSIQLEG-QGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEG----LFTLSLNIKFKNLIPVGSLAVLDIQVEKIEDQKLYMSCIAQSRDKQTVYAKSSG---------------------------------------VFLQLQLEEQSQEQ-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEW3-1", "uniprot_id": "A0A8I6AEW3_RAT", "id": "A0A8I6AEW3-1", "name": "", "aln": "MMRTGFQGVARLVHHKALYRSPQTLPRLHLASAFGSSTDSLVARFCGEKTDLKDYALPNASWCPDMLSLYQEFLEKTK---------SGSWVKLPSFKSNR----DHIRGLKLPFGLVAASDKQDWRLFTRSIQLEG-QGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEG----LFTLSFNIKFKNLIPVGSLAVLDLQVEKIEDQKLYMSCIAQSRDKQTVYAKSSGKEICSLSLGCLPLPNPQQGGKQRVKDQVLSWSLVLLGVGMLLARDMDEEKEKKTRIFLVRITQPAPLQDSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N1Q8-1", "uniprot_id": "THEM5_HUMAN", "id": "Q8N1Q8-1", "name": "Acyl-coenzyme A thioesterase THEM5", "aln": "MIRRCFQVAARLGHHRGLLEAPRILPRLNPASAFGSSTDSMFSRFLPEKTDLKDYALPNASWCSDMLSLYQEFLEKTK---------SSGWIKLPSFKSNR----DHIRGLKLPSGLAVSSDKGDCRIFTRCIQVEG-QGFEYVIFFQPTQKKSVCLFQPGSYLEGPPGFAHGGSLAAMMDETFSKTAFLAGEG----LFTLSLNIRFKNLIPVDSLVVMDVELDKIEDQKLYMSCIAHSRDQQTVYAKSSG---------------------------------------VFLQLQLEEESPQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566R0-1", "uniprot_id": "THEM4_RAT", "id": "Q566R0-1", "name": "Acyl-coenzyme A thioesterase THEM4", "aln": "MLRSCAMRLRTLG------------------ATPARRPEATRRLFSSEEVVCKDYALPNPSWTKDLRLLFDQFMKKCE---------DGSWKRLPSYRQNPPQALQEFQTHFVDSKFKKEEQMSKAQQFTRSLEEG--LGFEYAMFYNKAEKRIVCLFQGGLHLQGMPGFVHGGAIATIIDITAGMCAFSEGI-----VMTANLNIDYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSTDEKTLHTQATA---------------------------------------LFIKLDPDKPLT---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UUI3-1", "uniprot_id": "THEM4_MOUSE", "id": "Q3UUI3-1", "name": "Acyl-coenzyme A thioesterase THEM4", "aln": "MLRNCAMRLRTLG------------------ATPARRPGAARRLFSSEKVIRKDYALPNPSWTKDLRLLFDQFMKKCE---------DGSWKRMPSHRQNPTRAIQEFQTLFVDSKFKKEEQMSKAQQFTRSFEEG--LGFEYAMFYNKVEKRTVSLFQGGLHLQGVPGFVHGGAIATIIDVTTGTCAISEGV-----AMTANLNITYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSIDEKTLYTEATA---------------------------------------LFIKLDPEKPLT---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HHC8-1", "uniprot_id": "A0AC58HHC8_DANRE", "id": "A0AC58HHC8-1", "name": "Acyl-coenzyme A thioesterase THEM4", "aln": "MLAHIARRIGHFHGHQISSAILR-----RMRASLKTINPISAISLWTFSSQLQDFSQPNPSWSPEMRKFYDHYNAQCDTDTETYENKTGPWRKLPSYNRSIK--------HATGGIYISKLIQAKARLFTRSVNEQG-ATFEYVAFFNKEEKICICLFQPGHLLEGAPGHVHGGAIATMIDTVTGTLAGYLSGP----SVTANLNINYRSPVPLGSVVIIHCALDRIEGRKTFITCKVTSTDESKVYTEATADASIR--------------------------------YVLYYKITVAHSHLISAIQSK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40098-1", "uniprot_id": "FMP10_YEAST", "id": "P40098-1", "name": "Uncharacterized mitochondrial membrane protein FMP10", "aln": "MFKRIAIAQIRTYTNGVVFKT----------ASKPKRRWIPWTIFGG--SFLGGWYLTQHMTFTDLLAYWRYDALPKN---------ADEVVKYHADLNRRLNGLPIVKQLENAGFVQVIANEEENLLVSRALNTPGGVAIPPRVYYNPSRRETVGLYHLGMKLTGYPFLIHGGILATVIEDLMKEAIRLEKGTKNINQETKNLSISYKFPTLANQFVVVRTTDLQQYGNKTKLKAELMDQSGNRTLVKANAT----------------------------------------FSSEQGNPKEEK-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: : .: .: :: : . . : : . .:*..: ::: .: : *:: * * * * *** :*:::: * .:.* :: ...:: : ..* :.. . . . .::.. . ", "identical_positions": 14, "similar_positions": 59, "identity": "4.32%" }, { "cls_id": "homologset.agr.SGD:S000000985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D110-1", "uniprot_id": "MTHFS_MOUSE", "id": "Q9D110-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD-EVETEVIIKDIFKQGKICFIPRYQFQSNHMDMVRLTSSEEIALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQEVKPYTMALAFKEQICP--QIPVDEHDMKVDEVLYEDSPAS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N466-1", "uniprot_id": "L7N466_MOUSE", "id": "L7N466-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD-EVETEVIIKDIFKQGKICFIPQYQFQSNHMDMVRLTSPEEIALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQEVKPYTMALAFKEQICP--QIPVDEHDMKVDEVLYEDSPAS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXC0-1", "uniprot_id": "A0ABK0LXC0_RAT", "id": "A0ABK0LXC0-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALGAEERLRQSHLLTQKVIAHSQYQNSKRISIFLSMQD-EIETEEIIKDIFKQGKICFIPRYQFHSNHMDMVRLTAPEEVALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQKVKPYTLALAFREQICP--QIPVDEHDMKICHEDPNRTWNSGECSSAQRSYHITKSLWIASVKLEPTCGILSHMHIKTVRSHISVLWTVYNQTQIFSQKGVQKLPWVLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49914-1", "uniprot_id": "MTHFS_HUMAN", "id": "P49914-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD-EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTS-------WNIPQPGEGD-VREEALSTGGLDLIFMPGLGFD-KHGNRLGRGKGYYDAYLKR-CLQHQEVKPYTLALAFKEQICL--QVPVNENDMKVDEVLYEDSSTA--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2L0J2-1", "uniprot_id": "A0A0G2L0J2_DANRE", "id": "A0A0G2L0J2-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAALRA--AKQALRREIKSRVAAVSDQEKLRQSRVVSQKLFRHPKYLSSQRVAVFLNMHD-EVATEDILQDIFRRGKTCFIPRYFTKSSHMDMLRLKDMEDMETLPLTA-------WNIRQPGDDDKHREEALDTGGLDLILMPGLGFD-KSGNRLGRGKGFYDTYLER-CRTHPKGKPYTIALAFKEQICA--EIPVGEHDIVIDEVLHEDE-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLS1-1", "uniprot_id": "Q8MLS1_DROME", "id": "Q8MLS1-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAATIQNTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTAS-ELDTTALLSEMFRLEKMVFVPTYE--GSRMKMVRLRGMEEYESLPLTK-------WNIKQPDFKEAREDAMTNGHGIDLFIVPGVAFT-RCGARMGHGMGYYDKFLKQHAEKYPHKKISLMALSLNEQIVSNEELPMESHDVRLHSVITEN------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40099-1", "uniprot_id": "FTHC_YEAST", "id": "P40099-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "------MATKQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEIIKNLFQDGQEVFLPRCTHTSESKHFKLREDHHPHLIFHRMSSLKMVRDLKPQGPYQLKEPEPHIEESDILDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQVAS--PIPLEKHDYSMDCIVCGDGSIHWFQ-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** .:* : .:. : :* :: : .::*:: ::. . *: * ::.::*: : *:* .. .: . : : * . . . :*:.::**:.* : * *:*:* *:** :::: : * :.*.: **: :*: .:* : ", "identical_positions": 29, "similar_positions": 65, "identity": "10.21%" }, { "cls_id": "homologset.agr.SGD:S000000993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR57-1", "uniprot_id": "RL14_MOUSE", "id": "Q9CR57-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKAPAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63507-1", "uniprot_id": "RL14_RAT", "id": "Q63507-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAA---KAKVPAKKATGPGQKAAAQKASAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZHE6-1", "uniprot_id": "D3ZHE6_RAT", "id": "D3ZHE6-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYISFGSHAGKLVSFVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFRLRFTCSACQKYVRKAWEKADINTKSAATRWAKIIDARERKAKMTDFDRFKVIKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAT---KAKVPAKKATGPG-----QKAPAQKAAG-KAAPPAKGQKGQKTPAQKAPAPKATGKKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50914-1", "uniprot_id": "RL14_HUMAN", "id": "P50914-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAA--AAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38754-1", "uniprot_id": "RL14B_YEAST", "id": "P38754-1", "name": "Large ribosomal subunit protein eL14B", "aln": "MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAGVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVK---KALAKA------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P55841-1", "uniprot_id": "RL14_DROME", "id": "P55841-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MPFERFVQTGRIAKASAGPLKGRLVAIVDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTKYRIKFPYTAPTRIVRKAWTESDLKAQWKVSPWSVKAQNICKRSSLNDFDRFKLRYAKRQRNKLLTIAFNTLKKRTKADGTPR----------------------------------------VLKKDRRERLRAEKAKGGKKAAAKK-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:.**:. . * *:*.::*::***::.*:*** : * ** : : ** : :. * * : * :.: : .: *: ::: :.**:**:: :: :. :. : * : ", "identical_positions": 29, "similar_positions": 45, "identity": "12.89%" }, { "cls_id": "homologset.agr.SGD:S000000994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70297-1", "uniprot_id": "STAM1_MOUSE", "id": "P70297-1", "name": "Signal transducing adapter molecule 1", "aln": "MPLFATN-PFDQDVEKATSELNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLN-KGHPKVCEKLKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQ-----------SAPVSTLYP----------STSNLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMIKTEKKT--------------VQFNDDVQIETIEPEPEP--AFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYS-----------------MYAKLQSQQYYLQSSAVSASQVYP--------------------GPAQSGTYLVAGSAQMTH-------LQSYSLPPEQLSSISQGAVPSSANQ---ALPSQQTQASYPNAMVSSVQG-----NSYPSQASIYSPPA---------------AAAAAAAAAVVPVPVPADVTIYQNAGPTMSQVPNYTLTSSTLPQTGGSQQPPQPQQAYSQKALL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DF55-1", "uniprot_id": "B5DF55_RAT", "id": "B5DF55-1", "name": "", "aln": "MPLFATN-PFDQDVEKATSELNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLN-KGHPKVCEKLKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQ-----------AAPLSTLYP----------STSSLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEVITVLDDSDPNWWKGETHQGMGLFPSNFVTADLTAEPEMIKTEKKT--------------VQFSDDVQIETIEPEPEPEPAFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPVYS-----------------VYAKSQSQQYYVQASGVSAPQVYP--------------------GPAQSGAYLVAGNAQMTH-------LQSYSLPPEQLASISQGAVPPSATP---ALPNQQAQASYPNAMVSSVQG-----NSYPSQASIYSP------------------AAAAAAVAVTAVPVPADVTIYQNPGPNMSQVPNYTLTSSTLPHTGGSQQPPQPQQAYSQKALL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92783-1", "uniprot_id": "STAM1_HUMAN", "id": "Q92783-1", "name": "Signal transducing adapter molecule 1", "aln": "MPLFATN-PFDQDVEKATSEMNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLN-KGHPKVCEKLKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQ-----------STTLSTLYP----------STSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMIKTEKKT--------------VQFSDDVQVETIEPEPEP--AFIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYS-----------------MYAKLQNQPYYMQSSGVSGSQVYA--------------------GPPPSGAYLVAGNAQMSH-------LQSYSLPPEQLSSLSQAVVPPSANP---ALPSQQTQAAYPNTMVSSVQG-----NTYPSQAPVYSP------------------PPAATAAAAT-----ADVTLYQNAGPNMPQVPNYNLTSSTLPQPGGSQQPPQPQQPYSQKALL--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88811-1", "uniprot_id": "STAM2_MOUSE", "id": "O88811-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDRVGSTP-SGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAA-------AKNGTSLNKNKEDEDIAKAIELSLQEQKQQ-----------YTETKALYP----------PAESQLNN--KAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVETATVDKLN--------------VIDDDVEEIK--KSEPEP--VYIDEGKMDRALQILQSIDPKESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEAPVYS-----------------VYSKLHP-AHYPPAAAGVPVQTYP--------------------VQSHGGNYLGHGIHQVSV-------AQNYNLGPDPMGSLRS--LPPNMN----SVTAHTVQPPYLSTGQDTVSN-----PSYMNQSSRLQA-------------------AAGTAAYTQPVGMSTDVSSFQNTASGLPQLAGFPVAVPAPVAA-------QPQASYHQQPLL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHY7-1", "uniprot_id": "STAM2_RAT", "id": "Q5XHY7-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDRVGSTP-NGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKAMKEEGVTFPSAGSQTVSAA-------AKNGASLNKNKEDEDIAKAIELSLQEQKQQ-----------YPETKALCP----------PAESQLSN--KVARRVRALYDFEAVEDNELTFKHGEIITVLDDSDANWWEGENHRGAGLFPSSFVTTDLSTEVEAATVDKSN--------------VIDDDVEEIK--KSEPEP--VYIDEGKMDRALQILQSIDPKDPKPDSQDLLDLEDICQQMGPMIDEKLEEIDRRHSELSELNVKVLEALELYNKLVNEAPMYS-----------------VYSKLHP-APYSATAAGVPVQTYP--------------------VQSHGGNYLGHGIHQVPV-------AQSYNLGPDPMGSSRS--LPPNMN----SVTAHTIQPPYLSTGQDAVSN-----PSYMTQSSHLQA-------------------AAGTAAYTPAMGVSADLSSFQSTASGLPQLAGFPVAVPVPPAP-------QPQASYHQQPLL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75886-1", "uniprot_id": "STAM2_HUMAN", "id": "O75886-1", "name": "Signal transducing adapter molecule 2", "aln": "MPLFTAN-PFEQDVEKATNEYNTTEDWSLIMDICDKVGSTP-NGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIKSMKEEGITFPPAGSQTVSAA-------AKNGTSSNKNKEDEDIAKAIELSLQEQKQQ-----------HTETKSLYP----------SSEIQLNN--KVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTTNLNIETEAAAVDKLN--------------VIDDDVEEIK--KSEPEP--VYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLVNEAPVYS-----------------VYSKLHPPAHYPPASSGVPMQTYP--------------------VQSHGGNYMGQSIHQVTV-------AQSYSLGPDQIGPLRS--LPPNVNS---SVTAQPAQTSYLSTGQDTVSN-----PTYMNQNSNLQS-------------------ATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAGFPVTVPAHPVA-------QQHTNYHQQPLL--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XTL2-1", "uniprot_id": "Q9XTL2_DROME", "id": "Q9XTL2-1", "name": "", "aln": "MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNP-RLAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGKPLHLEVASRDFETEFRRLLA-KAQPKVSLKMRQVLKNWAENDYKNDRELDLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSA-PSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQP--VEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQPQGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQHPQQPPQQQGQQPPQHPQNSYHIDPQSQYAQVPPAVTQIQQPQQPPAPHAYMSPQHQQAPPPQGYQPGPNLYGPNGSPAVVNPQSYMSPQQQQQQHPPPHDQFSQLHQQMAAMSMAGGPPVGAPGYHMQNDAVKNNIPIYQQQR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38753-1", "uniprot_id": "HSE1_YEAST", "id": "P38753-1", "name": "Class E vacuolar protein-sorting machinery protein HSE1", "aln": "--MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDSFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMS-----------TQADNSDDEELQKALKMSLFEYEKQKKLQE-----QEKESAEVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKEEIEKEKNK----------------------------EAIVFSQKTTIDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMDRAANAH-----------------ISPPVPGPALYAGMTHANNTPVMP------------------------------------------------------------------------------PQRQSYQSNEYS----------PYPSNLPIQHP------------------------------------TNSANNTPQYGYDLGYSVVS-------------QPPPGYEQ------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ***. ::* *:*:** * :: : : :*: : .:* :::::* : ***. :: *:.*::* : . :: :. . * : : . .::.* .: : ::.:. : . :.::::: **:::** * . . : * : *:***:**: : * :**:* *::* **:: :**:* : . *:** .:**. : . * :: . .::.. *: . . : : .: .: : * : * :.: :: .* : :* * *: . * . : . . . : : . . . . . . * : * ", "identical_positions": 59, "similar_positions": 131, "identity": "8.5%" }, { "cls_id": "homologset.agr.SGD:S000000995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU86-1", "uniprot_id": "D3ZU86_RAT", "id": "D3ZU86-1", "name": "", "aln": "------------------------------------------------------------------------------MLFSLNEWLWQETYWLPPN--------VTWAQLEDRD--GLVFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFL-RMKQRPVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILYH-ESWLWTPALCWENYPHQTLNLALSWWYLLELGFYISLLITLPFDIK--RKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQRGCDTLFIIFSLVFFYTR--LVFFPTEVIYTAVFDS--------IKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRSDVEESDSSDDEA--VSEGP-QLKNGMARGSRAAITNGPRSRAAACLTNGHTRAT---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6J1-1", "uniprot_id": "CERS4_MOUSE", "id": "Q9D6J1-1", "name": "Ceramide synthase 4", "aln": "------------------------------------------------------------------------------MSFSLSEWLWQETYWLPPN--------VTWAELEDRD--GLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFL-RMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYH-ESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVK--RKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTR--LIFFPTQVIYTSVYDS--------IKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEP--VSEGP-QLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA82-1", "uniprot_id": "CERS4_HUMAN", "id": "Q9HA82-1", "name": "Ceramide synthase 4", "aln": "------------------------------------------------------------------------------MLSSFNEWFWQDRFWLPPN--------VTWTELEDRD--GRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFL-TEGHRPKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYH-ESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYLSLLIRLPFDVK--RKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTR--LVLFPTQILYTTYYES--------ISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAA--AAQEPLQLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEC1-1", "uniprot_id": "A0AB32TEC1_DANRE", "id": "A0AB32TEC1-1", "name": "", "aln": "-------------------------------------------------------------------MCIPLINGFMQLEDNINRWLWREDFWLPPG--------VTWKDIAEGTSDGSRHPVPRDLLISFPLALGFIALRFVFERVVALPLSRRLGVRDRVRLHITPIPKLEAFYLQKKKTEPSQEDLQALVKLCGLSERQIQSWLRRRRIQDRPANSRKFSEASWRFGFYLIIFSAGLISLIH-TPWFWDHRECWSGYPAQAVAEAQYWYYIIELSFYLSLLLCVSVDIK--RKDFQEQIIHHIATIFLIAFSYCANYVRVGTLVMLVHDSSDFLLESAKMFNYAGWRKTCDALFVVFAAVFLVTR--LIVFPFRIVYTAVVDS--------LDVFSPYPGYYFFNGLLLVLQALHIFWAWLILRMVHKFVFLGKVERDERSDDESEPDEDDEVG---EEEEERSWEHKKGALNSKLASLAN--NCVLNNLTNQRQKMNSRTLKER-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BAR8-1", "uniprot_id": "A0A8M2BAR8_DANRE", "id": "A0A8M2BAR8-1", "name": "", "aln": "-------------------------------------------------------------------------------MDALSRWFWKQEFWLPPG--------IVWEDLEEMQ--GSRRPMPRDLLLALPLALAFIMLRYAFERRVAFPLSRVLGVKDPVRLKVTPSPSLEAFYT-KNSRQPTQIEISGLVKQCGLTHRQVETWFRNRRNLDRPSNTTKFCEACWRFAFYLVAFTAGLLSLIN-TAWFWDQRECWRGFPRQPLQELHYWYYMLELSFYWSLLLCVSVDVK--RKDFKEQIIHHFATIFLLGFSYCSNYIRIGTLVMLVHDASDFLLESAKMFNYAGWKKTCDSLFVIFAAVFLVTR--LLVFPSKIIYTTLVLS--------MEVFEPFLGYYFFNALLLVLQALHIYWAYLILRMVYKFLFLGKLDKDERSDVETEPEEEEEEEKEEEEEEQRSWRKRKVVLDSRRAMLSS--SCVLNNLTQQKADAQ-RRPKAR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q924Z4-1", "uniprot_id": "CERS2_MOUSE", "id": "Q924Z4-1", "name": "Ceramide synthase 2", "aln": "------------------------------------------------------------------------------MLQTLYDYFWWERLWLPVN--------LTWADLEDKD--GRVYAKASDLYITLPLALLFLVIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYQ-TSGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVD-KPWFYDLRKVWEGYPIQSIIPSQYWYYMIELSFYWSLLFSIASDVK--RKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDASDYLLESAKMFNYAGWKNTCNNLFIVFAIVFIITR--LVIMPFWILHCTMIYP--------LELYPAFFGYYFFNFMMAVLQMLHIFWAYFILRMAHKFITG-KLIEDERSDREETE--------SSEGEETAAGAGAKSR--LLANG-----HPILNNNHPKND---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8V4-1", "uniprot_id": "G3V8V4_RAT", "id": "G3V8V4-1", "name": "", "aln": "------------------------------------------------------------------------------MLQTLYDYFWWERLWLPVN--------LTWADLEDKD--GRVYAKASDLYITLPLALLFLIIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYL-TVGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVD-KPWFYDLRKVWEGYPIQSIIPSQYWYYMIELAFYWSLLFSIASDVK--RKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNLFIVFAVVFIITR--LVIMPFWILHCTMIYP--------LEFYPAFFGYYFFNSMMVVLQMLHVFWAYFIVRMAHKFITG-KLVEDERSDREETE--------SSEGEEAAAGAGAKSR--LLANG-----HPILNNNHPKND---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G23-1", "uniprot_id": "CERS2_HUMAN", "id": "Q96G23-1", "name": "Ceramide synthase 2", "aln": "------------------------------------------------------------------------------MLQTLYDYFWWERLWLPVN--------LTWADLEDRD--GRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYL-TSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVD-KPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVK--RKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITR--LVILPFWILHCTLVYP--------LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITG-KLVEDERSDREETE--------SSEGEEAAAGGGAKSR--PLANG-----HPILNNNHRKND---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9X7-1", "uniprot_id": "E7F9X7_DANRE", "id": "E7F9X7-1", "name": "", "aln": "------------------------------------------------------------------------------MLAGLSELFWQERLWFPEG--------LGWADLEDRD--GRVYAKARDLWVALPIAVLFLLIRQLFEKYVATPLASLLGLKETVRRRVAHNPALESYYC-NTSKNPTQSSVEKLSKQTGWTERQVQRWFRRRRNQDRPNLLKKFCEASWRFAFYLLAFIGGLAALID-KPWLYDLEEMWKGFPTLTLLPSQYWYYMLELAFYTSLLFSVASDVK--RKDFKEQIIHHVATILLISFSWCVNYIRAGTLIMFMHDSADYLLESAKMFNYARWKNACNYIFILFAAIFIVTR--LIIFPFRIMYCTWVYP--------VTLYPPFFGYYFFNGLLMVLLCLHMFWAALIIRLAFRFLSSNSSVEDERSDRDETD--------ESEEEEELKNGEIKKKNGAAQNG-----HATYNNNHSKTE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B5Y1-1", "uniprot_id": "A0A8M2B5Y1_DANRE", "id": "A0A8M2B5Y1-1", "name": "", "aln": "---------------------------------------------------------------------------------MLSEWFWWDRLWLPRP--------VTWADLQDSE--GCVYARASHLYIILPVAVLLLGLRALYERLIAVPLAQALGVKDKIRKRASHNPLLETYYR-THSKHPTQADVKGVCKKLGWSERQVERWFRQRRNQDRPGVQKKFKEASWRFAFYLCSTFGGVLALYD-KPWFYDLREVWAKFPKQSLLDSQYWYYITEMSFYGSLLFSVAADVK--RKDFKEQLVHHWATLTLLSFSWCANYIRIGTLVMLVHDTSDVLLESAKMFNYAGWETTCNSVFVVFALVFMVTR--LIIFPFWLIHCTWVYP--------LDQFEPFFGYYFFNAMLMVLLFLHVFWASLILRMVKKFLFG-NLKGDERSDEEEDE--------GSEEEYTHAYTNGSGN--GLSNG-----H--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1A3B0-1", "uniprot_id": "CERS3_MOUSE", "id": "Q1A3B0-1", "name": "Ceramide synthase 3", "aln": "------------------------------------------------------------------------------MFQTFRKWFWSERYWLPPT--------IKWSDLEDHD--GLVFVKASHLYITIPYAFLLMVVRYFFEKFVATPLANALGIKKTQHK-IKPNAILENFFK-HSTSKPSHTDIYGLAKKCNLTERQVERWLRIRQKQNKPCRLQKFQESCWRFTFYLLITMAGAVFLYD-KPWAYDLWEVWNDYPRQPLLPSQYWYYILEMSFYWSLVFSLSTDIK--RKDFLAHVIHHLAAISLMSFSWCANYIRSGTLVMFIHDISDIWLESAKMFSYAGWKQTCNTLFFIFTVVFFISR--FIIFPFWILYCTLILP--------LHYLEPFFSYIFLNLQLMILQGLHVYWGYFILKMLNRCIFT-QNVQDVRSDNEEEE--------EEEEEEEAESTKGKET-EYLKNGLGTNRHLIANGQHGR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M5E6-1", "uniprot_id": "A0ABK0M5E6_RAT", "id": "A0ABK0M5E6-1", "name": "", "aln": "MGASGRAMAEWPGRMAARCRWDEHSSRKVTDIREHPHANLLPLSSAQTLHSVGLPRMHHCTACPAAFEAASSQGTGKRMFYRFRKWFWSERFWLPPT--------IKWSDLEDHE--GLVFVKASHLYITIPYALLLLVVRYFFEKFVATPLANALGIQKAQHK-IKPNAILENFFQ-HSTSQPSHNEVYGLAKKCNLTERQVERWFRIRQKQNKPCRLQKFQESCWRFTFYFMMTVAGAVFLYD-KPWAYDLWEVWYDYPRQPLLPSQYWYYVLEMSFYWSLVFSLGSDIK--RKDFLANVIHHLAAISLMSFSWCANYIRSGTLVMFVHDISDIWLESAKMFSYAGWKQTCNTLFFIFAIVFFISR--FIIFPFWILYCTLILP--------LHYLEPFFSYIFLNLQLMILQGLHIYWGYLILKMLNRCIFT-QNIQDVRSDNEEEEDEEEEEEEEEEEEEEEENTKGKET-EYLKNGLGTNRHLIPNGQHGR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IU89-1", "uniprot_id": "CERS3_HUMAN", "id": "Q8IU89-1", "name": "Ceramide synthase 3", "aln": "------------------------------------------------------------------------------MFWTFKEWFWLERFWLPPT--------IKWSDLEDHD--GLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRK-VTPNTVLENFFK-HSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYD-KPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWSLLFRLGFDVK--RKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISR--LIVFPFWILYCTLILP--------MYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFM-KSIQDVRSDDEDYE--------EEEEEEEEEATKGKEM-DCLKNGLRAERHLIPNGQHGH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C172-1", "uniprot_id": "CERS6_MOUSE", "id": "Q8C172-1", "name": "Ceramide synthase 6", "aln": "-------------------------------------------------------------------------------MAGILAWFWNERFWLPHN--------VTWADLK-NTEEAT-FPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAIALNIQANGPQTAQPNAILEKVFT-AITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQ-TPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIK--RKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTR--LGIFPLWVLNTTLFES--------WEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDE-----DSEPPGKKPHSSTTTNGTSGTNG-----YLLT--GPCSVDD--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A742-1", "uniprot_id": "A0A8I6A742_RAT", "id": "A0A8I6A742-1", "name": "", "aln": "-------------------------------------------------------------------------------MAGILAWFWNERFWLPHN--------VTWADLK-NTEEAT-FPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAVALNIQANGPQIAQPNAILEKVFT-AITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQ-TPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIK--RKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTR--LGIFPLWVLNTTLFES--------WEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDE-----DSEPPGKKLHSSTTTNGTSGTNG-----YLLT--GPCSMDD--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZMG9-1", "uniprot_id": "CERS6_HUMAN", "id": "Q6ZMG9-1", "name": "Ceramide synthase 6", "aln": "-------------------------------------------------------------------------------MAGILAWFWNERFWLPHN--------VTWADLK-NTEEAT-FPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPNAILEKVFT-AITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKK-TPWLWNTRHCWYNYPYQPLTTDLHYYYILELSFYWSLMFSQFTDIK--RKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTR--LGIFPLWVLNTTLFES--------WEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEE-----DSEPPGKNPHTATTTNGTSGTNG-----YLLT--GSCSMDD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JXZ1-1", "uniprot_id": "A0A0G2JXZ1_RAT", "id": "A0A0G2JXZ1-1", "name": "", "aln": "-----------------------------------------------------------------------MATAAAEALGLLWGWLWSGRFWLPQN--------VSWADLE-GPGDGYGYPRARHVLSVFPLAAGLFSVRMLFERFIAKPCALRIGIEDSAVYQVESNVTLEKVFT-SISKYPDEKRLKGLSKQLDWDVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYFCIFCYGVRFLWS-MPWLWDTRQCWYNYPYQPLSRELYYYYLTQLAFYWSLVFSQFIDVK--RKDFLMMFMHHLIAVTLISFSYINNMVRVGAIILCLHDSADSLLEAAKLANYARQERLCNTLFVIFGAAFMVTR--LGIFPLWILNTTLFES--------WEIIGPFPSWWLFNGLLLILQMLHVIWSYLIARTAFKALVRGKVSKDDRSDVESSSEED-----ETTHTN-NLSGSSSSNGANCMNGRMGGSHLAEEQGTCKAAGNLHFGASPRIHSCD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "----------------------------------------------------------------------------MDILNEFSNVFWSTHIWLPPN--------TTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYA-KSTR-LDKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWD-KPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK--RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTR--LGFYP-RIIYSSSVEA--------PRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRS--SDSEDLT-----DSSGNARLTNGSARSKNKSISSAP---SDKGSAGGAGSRAG-ARVATTERREE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38703-1", "uniprot_id": "LAG1_YEAST", "id": "P38703-1", "name": "Ceramide synthase LAG1", "aln": "-------------------------------------------------MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLN-SVFTPFVFGLFVFFWIYLRHVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQ-GIQKDERSDSDSDE--------SAENEESKEKCE-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .: . .. : . . : : . :: * : : * * : : :* . :*: . .*: . ::: ***: . ** :: *: *: : : * : * :* *. .* .* :* :* :: * . . : : . .. : : :: * * : : * ** . ", "identical_positions": 27, "similar_positions": 62, "identity": "5.26%" }, { "cls_id": "homologset.agr.SGD:S000000996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L579-1", "uniprot_id": "A0ABK0L579_RAT", "id": "A0ABK0L579-1", "name": "Small ribosomal subunit protein uS2m", "aln": "MELLGPCPRRQYPLPSGLPLWPPLLAVAPDPSKGNPFRICKCWRRGLGGTLAQTATARRRRSERCTAGVGPPSQQAALRPRALDPGGALPGRKSLCGISVHAPTMAPAPAVLTRLQCAGLR---RWPGFLQKAAPGPAGQNGRKVTGAPVPAVSEPQD---GDDFQSRILDVPLQHSDFFN--VKELFSVKSLFEARVHLGHKAGCRHRFMEPYIFGNRLGQDIIDLDQTALNLQLALNFTAHVAYRKGIILFVS-RNRQFSHLIETTAQACGEYAHTRYFKGGLLTNAQLL------------------FGPTVRLPDLIVFLHTLNNVFESHVAVRDAAKMNIPTVGIVDTNCNPCLITYPIPGNDDSPQAIQLFCKLFRTTINRAKEKRRQMEALHRLQSPK--GSEGTGTASAPDQSHSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924T2-1", "uniprot_id": "RT02_MOUSE", "id": "Q924T2-1", "name": "Small ribosomal subunit protein uS2m", "aln": "--------------------------------------------------------------------------------------------------------MAPAPAVLTRLLCAGVR---RWPGFLQKAIPGPAEQNGRKVTGAPVPAVSEPQD---GDDFQSRILDTPLQHSDFFN--VKELFSVKSLFEARVHLGHKAGCRHRFMEPYIFGNRLGQDIIDLDQTALNLQLALNFTAHVAYRKGIILFVS-RNRQFSHLIETTAQACGEYAHTRYFKGGLLTNAQLL------------------FGPSVRLPDLIIFLHTLNNVFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPIPGNDDSPQAIQLFCKLFRTTINRAKEKRRQMEALHRLQSPK--GSEGSGTSPVPDKSHSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y399-1", "uniprot_id": "RT02_HUMAN", "id": "Q9Y399-1", "name": "Small ribosomal subunit protein uS2m", "aln": "--------------------------------------------------------------------------------------------------------MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESED---STDFNDKILNEPLKHSDFFN--VKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFIS-RNRQFSYLIENMARDCGEYAHTRYFRGGMLTNARLL------------------FGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32902-1", "uniprot_id": "RT04_YEAST", "id": "P32902-1", "name": "Small ribosomal subunit protein uS2m", "aln": "-----MQRHVFARNFRRLSLLRNPSLTKRFQSSASGAANTPNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDKEQQLEAELSDFFRNYALLNKLFDSKTLDGQSSTTTAAATPTKPYPNLIPSANDKPYSSQELFLRQLNHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSLWRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGTRQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNPTERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNR-----LARNNEK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . *. * . .: : : :. .: * . *.*:* : * ::*.**:.* ****:.:. : :.**:*. . .****:** *: * :.. :: *****:. *: * * * : * *. **:: * : ..:.: :.*. :: * .: * * : *: :* * .:**:.*:**:.:*.*:***:****** :::: :: : *. ::* * * : ", "identical_positions": 69, "similar_positions": 84, "identity": "16.27%" }, { "cls_id": "homologset.agr.SGD:S000000999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61036-1", "uniprot_id": "PAK3_MOUSE", "id": "Q61036-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLDNEEKPPAPPLR------------------------MNSNNRDSSALNHSS----------KPLPMAPEEKNK---------------------------------KAR----------LRSIFPGGGDKTNKKKEKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKET--VNNQKYMSFTSG----------DKSAHGYI---AAHQSNTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DDNEPPPVIAPRPEHTKSIYTR------SVVESIASPAAPN-------------------------------KEDIPPSAEN-------------------------------ANSTTLYRN-------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLIIAAKEAIKNSSR------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62829-1", "uniprot_id": "PAK3_RAT", "id": "Q62829-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLDNEEKPPAPPLR------------------------MNSNNRDSSALNHSS----------KPLPMAPEEKNK---------------------------------KAR----------LRSIFPGGGDKTNKKKEKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFT---------------GIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKET--VNNQKYMSFTSG----------DKSAHGYI---AAHQSNTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DDNEPPPVIAPRPEHTKSIYTR------SVVESIASPAAPN-------------------------------KEATPPSAEN-------------------------------ANSSTLYRN-------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLILAAKEAIKNSSR------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75914-1", "uniprot_id": "PAK3_HUMAN", "id": "O75914-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDGLDNEEKPPAPPLR------------------------MNSNNRDSSALNHSS----------KPLPMAPEEKNK---------------------------------KAR----------LRSIFPGGGDKTNKKKEKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKET--VNNQKYMSFTSG----------DKSAHGYI---AAHPSSTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DENEPPPVIAPRPEHTKSIYTR------SVVESIASPAVPN-------------------------------KEVTPPSAEN-------------------------------ANSSTLYRN-------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLIIAAKEAIKNSSR------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88643-1", "uniprot_id": "PAK1_MOUSE", "id": "O88643-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNNGVDIQDKPPAPPMRNTSTM-------------------IGAGSKDTGTLNHGS----------KPLPPNPEEKKK---------------------------------KDRF---------YRSILPG--DKTNKKREKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKT--SNSKKYMSFT------------DKSAEDYN---SSNTLNVKTVSET--------------------------------------------------------------------------PAVPPVSEDDEDDDDD---------ATPPPVIAPRPEHTKSVYTR------SVIEPLP-VTPTR-------------------------------DVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQFL-KIAKPLSSLTPLMHAAKEATKNNH-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35465-1", "uniprot_id": "PAK1_RAT", "id": "P35465-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNNGLDVQDKPPAPPMRNTSTM-------------------IGAGSKDPGTLNHGS----------KPLPPNPEEKKK---------------------------------KDRF---------YRSILAG--DKTNKKKEKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKT--SNSQKYMSFT------------DKSAEDYN---SSNTLNVKTVSET--------------------------------------------------------------------------PAVPPVSED-EDDDDD---------ATPPPVIAPRPEHTKSVYTR------SVIEPLP-VTPTR-------------------------------DVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFL-KIAKPLSSLTPLIAAAKEATKNNH-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13153-1", "uniprot_id": "PAK1_HUMAN", "id": "Q13153-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNNGLDIQDKPPAPPMRNTSTM-------------------IGAGSKDAGTLNHGS----------KPLPPNPEEKKK---------------------------------KDRF---------YRSILPG--DKTNKKKEKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKT--SNSQKYMSFT------------DKSAEDYN---SSNALNVKAVSET--------------------------------------------------------------------------PAVPPVSEDEDDDDDD---------ATPPPVIAPRPEHTKSVYTR------SVIEPLP-VTPTR-------------------------------DVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFL-KIAKPLSSLTPLIAAAKEATKNNH-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9X9-1", "uniprot_id": "A0A8M9P9X9_DANRE", "id": "A0A8M9P9X9-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDNG-EVEDKPPAPPMRNTSTM-------------------IGSSGKDSGPLNHGS----------KPLPPNPEDKRR---------------------------------KEGF---------IRSILTG--GGDKTNKKKERPE-----------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKET--SNNQKYMSFT------------DKGVENFN---SSSAVVPKTVSET--------------------------------------------------------------------------PAVATVSEDEDEEEDE---------ATPPPVIAPRPEHTKSIYTR------SVIEPLPPPLSTK-------------------------------DAATSPITNAAADGGSSSNAPSSNTNTTNTNTTNTTNTTNTTSTSAASSTNAPSTPQTTDKSRKKKMSDEEILEKLNVLRSPSAGSIVSVGDPKKKYTRFEKIGQGASGTVYTAIDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHCNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAVFRDFLNRCLEMDVEKRGSAKELLQHQFL-KVAKPLSSLTPLIIAAKEAAKNNR-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CIN4-1", "uniprot_id": "PAK2_MOUSE", "id": "Q8CIN4-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDNG-ELEDKPPAPPVRMSSTI-------------------FSTGGKDPLSANHSL----------KPLPSVPEEKKP---------------------------------RNK----------IISIFSG-TEKGSKKKEKERPE-----------------ISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSN----TVKQKYLSFT------------PPEKDGFP---SGTPALNTKGSET--------------------------------------------------------------------------SAV--VTEEDDDDEDA-----------APPVIAPRPDHTKSIYTR------SVIDPIPAPVGDS-------------------------------NVDSGAKS-------------------------------------------------SDKQKKKAKMTDEEIMEKL--------RTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLILAAKEAMKSNR-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64303-1", "uniprot_id": "PAK2_RAT", "id": "Q64303-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDNG-ELEDKPPAPPVRMSSTI-------------------FSTGGKDPLSANHSL----------KPLPSVPEEKKP---------------------------------RNK----------IISIFSS-TEKGSKKKEKERPE-----------------ISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSN----TVKQKYLSFT------------PPEKDGFP---SGTPALNTKGSET--------------------------------------------------------------------------SAV--VTEEDDDDEDA-----------APPVIAPRPDHTKSIYTR------SVIDPIPAPVGDS-------------------------------NVDSGAKS-------------------------------------------------SDKQKKKAKMTDEEIMEKL--------RTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLILAAKEAMKSNR-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VI13-1", "uniprot_id": "PAK_DROME", "id": "Q9VI13-1", "name": "Serine/threonine-protein kinase Pak", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSEE----DKPPAPPVRLTSNRGGNER-----SGGGVGVGGGGLGGGGMGDVPPDM----------RPLPKEPDDSDR---------------------------------KKKT---------LKSKIKG----SKPSHTDSKPN-----------------ISYPTNFEHTVHVGFDAVTGEFT---------------GMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNTTKQ-RPSSKYMTNAIT----------THSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPA-------TPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNANLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPN--TRAANAKKKKMSDEEILEKL--------RTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFL-KLARPLASLTPLIMAAKEATKGN--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03497-1", "uniprot_id": "STE20_YEAST", "id": "Q03497-1", "name": "Serine/threonine-protein kinase STE20", "aln": "MSNDPSAVSELPDKDSLDNGISNDNERAMGGNGDGGDGLRLPRTTGTLNVNALQKGTNAAHEAGGYKSMDPAKNAETTNDDDNNVVSLDDPIQFTRVSSSSVISGMSSSMSPHSNIDETKSLEAVTPNINTSNITPDHSADNTFSTINASESDHQFNDTLLSKLSLTDSTETIENNATVKHQQPVASSTVNSNKSSTDIRRATPVSTPVISKPSMTTTPRQINSASHSLSNPKHKQHKPKVKPSKPEAKSKPVSVKKSFPSKNPLKNSSPPKKQTEKSYYSSSSKKRKSGSNSGTLRMKDVFTSFVQNIKRNSQDDKRASSSSNNSSSSSITTALRISTPYNAKHIHHVGVDSKTGEYT---------------GLPEEWEKLLTSSGISKREQQQNMQAVMDIVKFYQDVTETNGEDKMFKTFNTTTGLPGSPQVSTPPANSFNKFPPSTSDSHNYGSRTG--------------------------------------------------------------------TPMSNHVMSPTLNTDSSSANGKFIPSRPAPKPPSSASASAPIIKSPVMNS-----AANVSPLKQTHAPTTPNRTSPNRSSISRNATLKKEEQPLPPIPPTKSKTSPIISTAHTPQQVAQSPKAP-----------AQETVTTPTSKPAQARSLSKELNEKKREERERRKKQLYAKLN--------EICSDGDPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAPLVKLARLKKVAENMDADEDNDDDNDNEHINKTNNCDDNNDSKETVNLDVTEDDKQK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ::* *.. . : * *: . : . : . . . ..: ** * : :* ***.*: ***:* *:** * :** .*.*:* **::* ***:*::::::. .. : : . .. *. . : . . : ... *. * ...: . . : .: . . : .: : .::: ** * * ***. **: ******** *:** : . . .*****:**.:**************: *:**:**::***:: :*:*:***: *********. : *.**.***** *..*:***.: *:********:**.::*.:***********. : **:**************:** ******:****** ***:*********.**:*********.*:::: :.**. ::.**: ** :: : *.** :**:. :: ::*.. :**:**: *: . ", "identical_positions": 205, "similar_positions": 150, "identity": "19.6%" }, { "cls_id": "homologset.agr.SGD:S000001002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y120-1", "uniprot_id": "A0A8I5Y120_RAT", "id": "A0A8I5Y120-1", "name": "BRCA1-associated protein", "aln": "-----MSVSLVVIRLELAGHSPVPADFGFSAAAGEMSNEEIKKKTLASAAACLEGKSPGEKAAIIHQHLGRREMTDVIIETMKASADEFRDTSEEKTSSAAPSSAQRSREQS-ESVNTVPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCVLTVPATMTSHDLMKFVAP---FNDVIEQMKIIRDSTPNQ---YMVLVKFSAQADADSFYMACNGRQFNSIEDD-VCQLVYVERAEVLKSEDGASLPVMDL------------------TELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVE--------ENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYL------------------LTSQLESQRVYWENKIVRIEKDTAEEINNMKSKFK---ETIEKCDSLELRLSDLLKEKQSVERKCTQLSTRVAKLSTELQEEQELNKCLRANQLLLQNKLKEEERLLKETCAQKDLQITEIQEQLRDVMFYLETQQQISHLPAETRQEIQEGQINIAMASAPNPPSSGAGGKLQSRKGRSKRGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MP8-1", "uniprot_id": "BRAP_MOUSE", "id": "Q99MP8-1", "name": "BRCA1-associated protein", "aln": "-----MSVSLVVIRLELAGHSPVPTDFGFSAAAGEMSDEEIKKKTLASAVACLEGKSAGEKAAIIHQHLGRREMTDVIIETMKARADEVRDTVEEKKPSAAPVSAQRSREQS-ESVNTAPESPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCVLTVPATMTSHDLMKFVAP---FNDVIEQMKIIRDSTPNQ---YMVLIKFSAQADADSFYMACNGRQFNSIEDD-VCQLVYVERAEVLKSEDGASLPVMDL------------------TELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVE--------ENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYL------------------LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFK---ETIEKCDSLELRLSDLLKEKQSVERKCTQLNTRVAKLSTELQEEQELNKCLRANQLVLQNQLKEEEKLLKETCAQKDLQITEIQEQLRDVMFYLETQQQISHLPAETRQEIQEGQINIAMASAPNPPSSGAGGKLQSRKGRSKRGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z569-1", "uniprot_id": "BRAP_HUMAN", "id": "Q7Z569-1", "name": "BRCA1-associated protein", "aln": "-----MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAP---FNEVIEQMKIIRDSTPNQ---YMVLIKFRAQADADSFYMTCNGRQFNSIEDD-VCQLVYVERAEVLKSEDGASLPVMDL------------------TELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVE--------ENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYL------------------LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFK---ETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHR2-1", "uniprot_id": "A0A0B4KHR2_DROME", "id": "A0A0B4KHR2-1", "name": "BRCA1-associated protein", "aln": "MDLNPENISLCVIKIETD-LDPSADSEGAVSAEHPTNPRVLKERERDRGLR----QSRDITIETYTNQRWKRELSEPRQQEMN----WVAAVQHVNSPSAGSSREITPRSGD----DGQAGASASNFPQEIGYFSGNPIVEVTKGLIHLYKKNERKAIKEAP--SNQLCLLAVPATLNCHDLLNFIAP---CHAEIKHIQIVRDGSPNQ---FMVLLEFRSNESALEFYKSYNGSTYNSLEPDSLCHAVWVS--EVERSEHGA--PPMGH------------------TELPTCPVCLERMDESVDGVLTILCNHAFHASCLMKWGDSTCPVCRHVQTPGLVE--------DSVCMECEGTDSLWICLICGHVGCGRYQGGHAAAHFRATNHTFAMQLGTSSVWDYAGDNFVHRLFQNKSDGKLVASQTEKDER-EEKIDSMQMEFTYL------------------LTSQLDTQRKYYEERMERLEQ----EWQNHKATAN---DAKTEVSELQQLQQNMQKEKVNLERKLAQHTAKLKDVQKQLNEERELSKALQSNQSSWHGKYKLLEQQYNEFKQTHDAEVTELKEQLRDIMFFLDNQQKLANT------EIAGGTVTGIAEKEPDPNTR--------RRNRRKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38748-1", "uniprot_id": "ETP1_YEAST", "id": "P38748-1", "name": "RING finger protein ETP1", "aln": "-----MDQFEYIITLEFGNQNQVES----AYQIFKSIPKKLKAKSIG-----------EESIKSNNQDWQDWRVCDLEIDMIT---------------------------------DFKNQTSKEEESDLITSQYLGHGIIRLFKLSNANNTLNEKEILTIPGDDTMICILFVPTYFTVHDLLHFYIGDDIVNKQVSNFRILRNQQKGMGFNFTVLIKFRNALDAKNFKEEFNGKSFSRMDPE-TCHVISVKEIVFQKKLFQRPAANEDFPYLLTDPFTVKKKKELVKVELPTCPVCLERMDSETTGLVTIPCQHTFHCQCLNKWKNSRCPVCRHSSLRLSRESLLKQAGDSAHCATCGSTDNLWICLICGNVGCGRYNSKHAIKHYEETLHCFAMDIRTQRVWDYAGDNYVHRLVQNEVDGKLVEVGGSGDDDNNDIGNSDELQNVVYGNRSKNGEKSNSNKKDGELAANFLRHREYHLEYVQVLISQLESQREYYELKLQEKDQTASDSSNVESLKKSMEDLKLQFQVTQKEWQKREMAQKSKLEEDMLVIEGLQANLDHLSKKQEQLERENKALEESK----QDLEEQVKDLMFYLDSQEKFKDAD----ESVKEGTILIQQPHGAAQASKS-----KKKRNKNKKAGK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :* . . :* . :. .: : : :. : :. .: .: * . : : : :. : . : . :*:* **: :. ***::* : :.:::*:*: . : **::* .* .* ** :. :: : *: : *. . :. . . .***.*.*******... *::* *:*:**..** :* :: *****: . * . * * :.********::***** . ** *:. * * :**:: . ********:****. .: ***:* . * :: :: ::: *:::: :* * : : : . : : : . : :: . ..:: ..: . * ..: . : : .:*:*: : : *::* : : *: : : :::**::*:**:*:.*::: . .: * : . : ::.: *: ", "identical_positions": 106, "similar_positions": 175, "identity": "16.26%" }, { "cls_id": "homologset.agr.SGD:S000001003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CS42-1", "uniprot_id": "PRPS2_MOUSE", "id": "Q9CS42-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPN--IVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYII-QSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENITEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINSAAFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09330-1", "uniprot_id": "PRPS2_RAT", "id": "P09330-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPN--IVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYII-QSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENITEWRNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11908-1", "uniprot_id": "PRPS2_HUMAN", "id": "P11908-1", "name": "Ribose-phosphate pyrophosphokinase 2", "aln": "-----------------------------------------------MPN--IVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYII-QSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60892-1", "uniprot_id": "PRPS1_RAT", "id": "P60892-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPN--IKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7G0-1", "uniprot_id": "PRPS1_MOUSE", "id": "Q9D7G0-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPN--IKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60891-1", "uniprot_id": "PRPS1_HUMAN", "id": "P60891-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MPN--IKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UXL2-1", "uniprot_id": "G3UXL2_MOUSE", "id": "G3UXL2-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "-----------------------------------------------MSN--IKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD-----------------------KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VT33-1", "uniprot_id": "Q9VT33_DROME", "id": "Q9VT33-1", "name": "ribose-phosphate diphosphokinase", "aln": "MPDKKCTENEQNDCVMPVRSANPIRARSLIRDNLEKQAGCLNLIHSRMPN--IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV-QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38689-1", "uniprot_id": "KPR3_YEAST", "id": "P38689-1", "name": "Ribose-phosphate pyrophosphokinase 3", "aln": "-----------------------------------------------MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGVVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKD-----------------------KSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVN-YMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLFKNYPL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. * ::: * .*:: :..***::* . *: .. *....******.:*::*: * *.* :**.::********.* **: *:**:** *******:** :*****:***:*:**:.**.**:***************:*********:*:::*:**: : :. *:*********.:::****:::******** :**** *******.*::.*:**********: :**: *:. *. * **:***::** **..**.: :: ** ***:* : :::.*.*: **:* ::**::** *****:****.: * ", "identical_positions": 177, "similar_positions": 99, "identity": "45.27%" }, { "cls_id": "homologset.agr.SGD:S000001004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K542-1", "uniprot_id": "A0A0G2K542_RAT", "id": "A0A0G2K542-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSQMVFNLSKAMSQDGASQFQEVILQELELSVKKELEKILTTATSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQK-YNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNPKTLDG---GLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZJ5-1", "uniprot_id": "UGPA_MOUSE", "id": "Q91ZJ5-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSRFVQDLSKAMSQDGASQFQEVILQELELSVKKELEKILTTAASHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQK-YNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLGAVKRLQEQNAIDMEIIVNPKTLDG---GLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16851-1", "uniprot_id": "UGPA_HUMAN", "id": "Q16851-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQK-YNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDG---GLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDY2-1", "uniprot_id": "F1QDY2_DANRE", "id": "F1QDY2-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "---------------------------------------------------MLCLSKELLSNSN---GMAQFQEVMRQQLESSMHVELEKLLSTAKGAGAEVSKKDFEGFRKLFHRFLQVKGPSVEWPKINRPPEDSIQPYDKIK-AKGLPDNIADSLNKLVVVKLNGGLGTSMGCKGPKSLISVRNENTFLDLTVQQIEHLNKTYNADVPLVLMNSFNTDEDTKKILQK-YTHHRVKIHTFNQSRYPRINKESLLPVAKDMGMTGENGDVWYPPGHGDIYASFYNSGLLEQLIAEGKEYIFVSNIDNLGATVDLYILNHLVSQPNGKR-CEFIMEVTDKTRADVKGGTLIQYDGKLRLLEIAQVPKAHVDEFKSVTKFKIFNTNNLWISLSAIKRLQEQNAMDMEIIVNPKTIDG---GLNVIQLETAVGAAIKCFDNALGINVPRSRFLPVKTTSDLLLVMSNLYSLDAGSLTMSEKREFPTTPHVKLGS-SFTKVQEYITRFESIPDMLELDHLTVSGDVTFGKHVSLKGTVIIIANHGDRIDIPAGSMLENKIVSGNLRILDH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B230-1", "uniprot_id": "A0A8M2B230_DANRE", "id": "A0A8M2B230-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "MTLFTLLNAVNDRNSTECFMIGPSRSSSTSDWSVSKHQTHTPHSCDTSAVRPRCTVSEHLYRSSPNAGMAEFQEKLRLQHENSMHTELEKLLSTAKTPEAEISRKDFEGFKKLFHRFLQEKGPSVDWAKIQRPPEDSIQPYEKIK-LKGLPADVASSLNKLAVLKLNGGLGTSMGCKGPKSLISVRNENTFLDLTVQQIEHLNKTYNADVPLVLMNSFNTDEDTKKILQK-YTHHRVKIHTFNQSRYPRINKESLLPVATNMGLTGENEEAWYPPGHGDIYASFYNSGLLDKLIAEGKEYIFVSNIDNLGATVDLHILNHLMSQPNDKR-CEFVMEVTDKTRADVKGGTLTQYDGKLRLLEIAQVPKAHVDEFKSVTKFKIFNTNNLWMSLPAIKRLHEKNAMDMEIIVNPKTLDG---GLNVIQLETAVGAAMKSFDNALGINVPRSRFLPVKTTSDLLLVMSNLYSMNAGSLTMSPKREFPTTPHVKLGS-SFTKVRDFLKRFESIPDMLELDHLTVSGDVTFGKQLTLKGTVIIIANHGDRIDIPAGAMLENKIVSGNLRILDH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSW1-1", "uniprot_id": "Q9VSW1_DROME", "id": "Q9VSW1-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "------------------------------------------MPSGIRPIDVLLERAGVRGHQRAPSDSKEFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAEMGRFADLFGRFIQEEGPALDWNKIQKLPENAVMNYSNLKSPKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLTVQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRK-YKGFRVQIHTFNQSCFPRISREHYLPVAKDFDVEKD-MEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEERATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANLAAIDRVLRERTLNMEIIVNNKTLEN---GTRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDLLLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVTFGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38709-1", "uniprot_id": "UGPA2_YEAST", "id": "P38709-1", "name": "Probable UTP--glucose-1-phosphate uridylyltransferase", "aln": "--------------------------------------------------------MTVFSGVNKIEFEGTFEGIGKDVVMSQMIRALQKHFPSIRDKNYEFS-----LFLHIFQRYVLENTSITHDLVCDKIRLPIIDEVVELDDIKNYGLLEGKLLSKLAILKLTGKANPIIGKESP--LFEVKNGMSSLDVIVRQTQNLNVRYNSDVPLIFMTSLETESQVSNFLEEHYSSSKVRWKTVVQSSFPQIDKDRLLPIDLQINSHEN--DFWYPCGTGNLTDTLYFSGELDKLIAQGKEILFVSNVDNLGATGDLNILNFIINEK-----IEYLVEVVERTANVSNTGVLATYKGKLRSVYYNCLSNE------SASTCRIVNTNNIWIDLKKLKVLIESNSLNLPIHSSESKITHKNEEIECLQFKTQLVDCIAFFPNSRVLKVSRDRFLPLRTCKDLFLLKSTLYDLDSNGTFNLYPLKFGLLPSIDLGD-EFATYETFKIGVPDIPNILELEHLTVMGNVFFGRNITLKGTVIIICDENDVITVPDGSILENVTIWHKSQLEDMNGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : ::: : : * .:* *:: : . . :: : ::. :. . *.**.::**.* .. :* ..* :: *:. : **: *:* ::** *:::***::*.*::*:.:..:::.: *. :*: *. ** :*:*.:: **: :.. : : *** * *:: :: ** *. :* :*:* *:**:****** ** *** ::. *:::**.::* : *.* ..*** : :. *... ::.****:* .* :. : ...:::: * . ..: . :*::* : .: * .: ::*.*.****::. .**:*: *.** :. .. * * :.**. *:. . : . .**:::**:**** *:* **: ::*:******.:..* * :* *::*** : : :: * ", "identical_positions": 124, "similar_positions": 176, "identity": "21.75%" }, { "cls_id": "homologset.agr.SGD:S000001005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX46-1", "uniprot_id": "D3ZX46_RAT", "id": "D3ZX46-1", "name": "ubiquitinyl hydrolase 1", "aln": "-------MDDTEH-----ELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQLLSDIARLEAEMEQRHEQELEKFG--EN------------PESGVDSVTADLKKMNLENMPP---RPAKSQKRRDRR----ANLERRRQE-RMPAAQ-AEQLAAYRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLV---------FSVTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHKASWGGQLELRALSHVLQTPIEVVQANSPIIVIG-EEYTRKPLTLVYLHYACDFGEHYNSVKPIEVPGAVGGMAPRLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IE21-1", "uniprot_id": "OTU6A_MOUSE", "id": "Q6IE21-1", "name": "OTU domain-containing protein 6A", "aln": "-------MSDTEQ-----ELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQMLADISRLEAEMEQRHKQELEKFG--EN------------PDSSVDSVTADLEKMNLENMPP---RPPKAQKRRDRR----AHQERRHQE-RMPAAQ-AEQLAANRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLV---------FSVTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHNASWGGQLELRALSHVLQTPIEVVQANSPTIVIG-EEYTRKPVTLVYLHYACDFGEHYNSVKPIEVAGAFGGMAPRLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L8S5-1", "uniprot_id": "OTU6A_HUMAN", "id": "Q7L8S5-1", "name": "OTU domain-containing protein 6A", "aln": "-------MDDPKS-----EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQ--D--------------DSSIESVVEDLAKMNLENRPP---RSSKAHRKRERM----ESEERERQESIFQAEM-SEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLV---------FSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIG-EEYVKKPIILVYLRYAYSLGEHYNSVTPLEAG-AAGGVLPRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2H2-1", "uniprot_id": "OTU6B_MOUSE", "id": "Q8K2H2-1", "name": "Deubiquitinase OTUD6B", "aln": "-------MEEVVAEE-LDDEEQLVRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEREMEQKHREELEQLKQLTF------------KDSKIDSVAVNISNLVLENQPP---RISKAQKRREKK----AALEKEREE-RIAEAE-IENLSGARHLESEKLAQILAARELEIKQIPSDGHCMYGALEDQLRE------QDCALTVASLRRQTAEYMQTHSDDFLPFLTNPSTGDMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILQTPIEILQADAPPIIVG-EEYPRNPLVLVYMRHAYGLGEHYNSVTRLVNSATENCS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M0-1", "uniprot_id": "OTU6B_HUMAN", "id": "Q8N6M0-1", "name": "Deubiquitinase OTUD6B", "aln": "-------MEAVLTEE-LDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLK-LTT------------KENKIDSVAVNISNLVLENQPP---RISKAQKRREKK----AALEKEREE-RIAEAE-IENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKE------KDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVG-EEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV00-1", "uniprot_id": "OTU6B_DANRE", "id": "Q7ZV00-1", "name": "Deubiquitinase OTUD6B", "aln": "-------MEEVET-----AEEQLAKQHRKEKKDLQAKIQSMKNAVPKNDKKRRKQLTEDIAKLEAELSQKHENELKLQNTSSV------------EEVSDALDSMSVANHEEQSDPSKQSRTSKAQKRRDKK----AALEKEREM-RIAEAE-VENLSGSRHQEGLKLREKLVERHLQIKEISSDGHCMYRAVEHQLTE------RGLALGLKELRDQTAQYMRSHADDFMPFLTNPNTGDMYTAEEFEKYCSDVADTAAWGGQLELKALSQVLQLPIEVIQADSPCITIG-EEYDKPKITLIYMRHAYGLGEHYNSVEPLKDLANEEEG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUN9-1", "uniprot_id": "Q9VUN9_DROME", "id": "Q9VUN9-1", "name": "ubiquitinyl hydrolase 1", "aln": "MCDGDVAIAELESRLDEVSLEDIGARHRRERKDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQRHKAELKAAEAMEAPVLVEPVV-KEPAEKPETEVTDDDGIEEKEEQLAPNQRVSKAQKRRDKK----AKEARAREAEIKTELQNAANQPTPKLIELQQITAKLSQRQLSLHNIPSDGDCLYQSIRHQLIVN-----ALPGHSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHDIAKTHAWGGHIELKAISSLLRVPIEVIQAEGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYNSTVPAA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38747-1", "uniprot_id": "OTU2_YEAST", "id": "P38747-1", "name": "OTU domain-containing protein 2", "aln": "-------MTGMESGENLENMEDILARHRKENKDLQNKITGMKKQATKS---KRKEVNSKCLDLQDKLKTKQENEIRDWKIANNEVFDAEQEDEVTPEKLLEQLSISRDEKEQQNVPVQQQQQGQTKKRRNRQKERLAKRDAAIAKMKEEAALEASKQPDLKKMEQESIDQLCELKKLKQFDIQPDGHCLFASILDQLKLRHDPKKLDQDMDVMKLRWLSCNYVQEHRDDFIPYLFDEET---MKMKDIDEYTKEMEHTAQWGGEIEILALSHVFDCPISILMSGRPIQVYN-ECGKNPELKLVYYKHSYALGEHYNSLHDS--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :* :*.::** :: :* ..*. :**:. . :: :: ::. *:. : . :. : :::::*:: : . : * .: : *. * .**.*:: :: .** : ** :. *:: * :.::.:: . .: .:: * :: . ***.:*: *:* :: **.:: : . . * : : * :: :* **** ", "identical_positions": 38, "similar_positions": 91, "identity": "11.34%" }, { "cls_id": "homologset.agr.SGD:S000001006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NTK5-1", "uniprot_id": "OLA1_HUMAN", "id": "Q9NTK5-1", "name": "Obg-like ATPase 1", "aln": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQAS-AENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEK---VAVRGG--DKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELS--------AEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEG---SENAVKAAGKYRQQGRNYIVEDGDIIFFKFNT---PQQPKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZ30-1", "uniprot_id": "OLA1_MOUSE", "id": "Q9CZ30-1", "name": "Obg-like ATPase 1", "aln": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQAS-AENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPILDKLEK---VAVRGG--DKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELS--------AEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKDEG---SENAVKAAGKYRQQGRNYIVEDGDIIFFKFNT---PQQPKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0JPJ7-1", "uniprot_id": "OLA1_RAT", "id": "A0JPJ7-1", "name": "Obg-like ATPase 1", "aln": "MPPKKGGDGLKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQAS-AENFPFCTIDPNESRVPVPDERFDFLCQCHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEK---VAVRGG--DKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLLLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKSDPGALVIPFSGALELKLQELS--------AEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYDDFKDEG---SENAVKAAGKYRQQGRNYIVEDGDIIFFKFNT---PQQSKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZU42-1", "uniprot_id": "OLA1_DANRE", "id": "Q7ZU42-1", "name": "Obg-like ATPase 1", "aln": "MPPKKGGDGPKQPPLIGRFGTSLKIGIVGLPNVGKSTFFNVLTKSQAA-AENFPFCTIDPNESRVPIPDERFDFLCQYHKPASKVPAFLNVVDIAGLVKGAHAGQGLGNAFLSNIFACDAIFHMTRAFEDEDIIHVEGCVDPVRDIEIIHEELRMKDEEMIGPIIDKLEK---TAVRGG--DKKLKPEYDIMCKVKSWVVDEKKHVRYYHEWNDKEIEVLNKHLFLTSKPMIYLVNLSEKDYIRKKNKWLVKIKEWVDAHDPGALVIPLSGGFESKYQDMS--------DEEKQKYCEENKTQSILTKIIKSGYSALQLEYFFTAGPDEVRAWTVRKGTKAPQAAGKIHTDFEKGFIMAEVMKFTDFKEEG---SENAAKAAGKYRQQGRNYIVEDGDIIFFKFNT---PNQPKKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SWU7-1", "uniprot_id": "OLA1_DROME", "id": "Q8SWU7-1", "name": "Obg-like ATPase 1", "aln": "MPPKK-HDEPERKPLIGRIGTNLRIGIVGVPNVGKSTFFNVLTQSAAP-AENFPFCTIKPNESRVPVPDERFDYLVEYHKPASVVPAYLNVVDIAGLVKGAAEGQGLGNDFLSHISACDAIFHLCRAFEDPDVTHVEGEVDPVRDLEIISEELRLKDEENLLKNLDKLEK---VVARGG--DKKLKPEYDSMLKIKDILIDQKRHLR-FEDWNAHDIEALNKYLFLTSKPVIYLVNLSDKDFIRKKNKWLPKIKEWIDKNDPGALLIPFSGAFEHQLTEKD--------ELERKAYETETKCKSMLEKIVVTGYKGLQLEYFFTAGPDEVKAWTIQKGTKAPQAAGRIHTDFEKGFIMAEVMHFEDFKAEG---SEANAKAAGKYRQQGRNYTVEDGDIIFFKFNAGAGLKDAKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38746-1", "uniprot_id": "YLF2_YEAST", "id": "P38746-1", "name": "Obg-like ATPase homolog", "aln": "---MNIGGGK---FLLGRISNNPTSGIVGLANVGKSTFFQAITNSKLGNPANYPFATIDAECAKVNIPSVPLSNLLRIYQSAKCVPGTLTIYDIAGLTRGASQGHGLGNKFLNDIRHVEGIFQVVRGFLKEDITHIEGNVDPVRDLSVVQDELILKDLEFLENIRERLSKKMRMVSKNSKEHQEMKIETELLDALEEHLFNGKKIRHFKDHWNLDEVKILNKHNFLTSKPTLILLNVSPQDYVRNENKFVRNIIEWINEFSPGDKFLLFSAEFESQLMECKGIASEYFDKIKEDTNVSDQQLVSAIPQIILEMRKLLNLISFFTCGPQEVHQWNIREGTTAQEAAGVIHSDLRETFISADVIKYDDLKKMEPPLNESLLKSKGLIKRAGKQYIMQDNDIALFKAAG----GKIKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::**:... ****:.********:.:*:* . *:**.**..: ::* :*. :. * . ::.*. :*. *.: *****.:** *:**** **..* :.**:: *.* . *: *:** ***:**:.:: :** :** * : ::*.* . :.. .:::* * : : ::. :.: *: : ..** .::: ***: :***** : *:*:* :*::*::**:: :* **:: .** .: :*. :* : : . :.. * : :*: *:* ***.**:**: *.:::**.* :*** **:*:.: ** *:*::: *:* .* *: * :: *::* ::*.** :** . ** ", "identical_positions": 128, "similar_positions": 143, "identity": "30.77%" }, { "cls_id": "homologset.agr.SGD:S000001007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60868-1", "uniprot_id": "RS20_RAT", "id": "P60868-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MAFKDTG------------------------------------KTPVEPEVAIH--RIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R987-1", "uniprot_id": "M0R987_RAT", "id": "M0R987-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MAFKDTG------------------------------------KTPMEPEVAIHLHRIRITLTNRNMKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60866-1", "uniprot_id": "RS20_HUMAN", "id": "P60866-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MAFKDTG------------------------------------KTPVEPEVAIH--RIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60867-1", "uniprot_id": "RS20_MOUSE", "id": "P60867-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MAFKDTG------------------------------------KTPVEPEVAIH--RIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AG52-1", "uniprot_id": "A0A8I6AG52_RAT", "id": "A0A8I6AG52-1", "name": "Small ribosomal subunit protein uS10", "aln": "MNLDLHIKRQLIFLSPGGACRGAFSSLLCPDSLLFAPAEEQVGQEAAPQPWHLKTPVEPEVAIH--RIRIMLTSRRVKSLEKVCADLIRGAKEKNLKVKGPVRTSTQTLRITTRKTPCGEGSETWGRFQIRIHKRLIDLHSPSEIVKRITSNSIEPGVEVEVTIADA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55828-1", "uniprot_id": "RS20_DROME", "id": "P55828-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MAAAPKD----------------------------------IEKPHVGDSASVH--RIRITLTSRNVRSLENVCRDLINGAKNQNLRVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRIIDLHSPSEIVKKITSINIEPGVEVEVTIAN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38701-1", "uniprot_id": "RS20_YEAST", "id": "P38701-1", "name": "Small ribosomal subunit protein uS10", "aln": "----------MSDFQKE------------------------------------KVEEQEQQQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVASN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : :*** **. .::.**:*. :::..*:::** ***** .*:.*:*:***** ****:** :::***** ***.:* :***:**. .*****:***.:*. ", "identical_positions": 54, "similar_positions": 38, "identity": "32.34%" }, { "cls_id": "homologset.agr.SGD:S000001008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q49B93-1", "uniprot_id": "SC5AC_MOUSE", "id": "Q49B93-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKT------------------------TSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGAS--FFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNH---VGGFNNVLEKAGNGS------------------RLHIVDFDVDPLRRHTFWT-ITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHF---------KDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFP-HLSDKLSTWISKGLCILFGIMCTSMAVVASLMG-SVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGG--LLTGITLSFWVAIGSFIYPAPESK-TLPLPLSTEHC--------------VELNITTTVAPQISS---------RPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSY--------------SNS-VPEKTTYF----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARH5-1", "uniprot_id": "A0A8I6ARH5_RAT", "id": "A0A8I6ARH5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MAVKSFEAWDYVVFAALFVISSGIGVFFAIKERKKT------------------------TSREFLVGGRQMSFAPVALSLTASFMSAVTVLGTPAEVYRFGAS--FLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYAATIIYILQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNH---VGGFDNVLEQARNGS------------------RLDIVDFDVDPLRRHTFWT-IAVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYY---------KDCDPWTSGAILAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFP-HLSDTLSTWISKGLCLLFGIICTSMAVLASLMG-SVVQ-----------------------------GALGG--LLTGITLSFWVGIGAFVYPAPDSK-TLPLPLSTEFC--------------VQQNKTTTEAYQLSS---------RPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGRQRGKDVDPLLIRPVCNLFCFWSKKYKTLCWCGVRHDQETEQDYLDSGSAWKQGVESGLQNGLKQDTLSQIPAYNPKDKSY--------------PKS-VQEKTTYF----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7T384-1", "uniprot_id": "SC5AC_DANRE", "id": "Q7T384-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------METVGRFQAGDYVVFACLFVVSSGIGVFFAIKERNKA------------------------PSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGAS--YVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFC--KLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSR---AGGIENVWSTSRTGG------------------RLQVFDFDVSPLRRHTFWT-LSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYY---------SHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVSQCFP-DLSNRAASWISKALCVAFGVACTTMAVAASYMG-GIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGG--LIVGISLSFWVGVGAFIYPAPSNN-THALELNTAGCN----------ITAAAFEPTSATVTQLTSD--------RNWLADSWYSMSYLYYSAVGFIGTVAAGLLITLLTGPMDPKLLKPGMTRSVKEVMCFCTEKFTEADLG------EGKEDVGDFGKAWEKHPDQGCT--LRMDEKFRCSCDNQQENGN--------------TNAGFDHNETSIVQKKL-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3Z9E5-1", "uniprot_id": "D3Z9E5_RAT", "id": "D3Z9E5-1", "name": "Sodium-coupled monocarboxylate transporter 1", "aln": "--------------------------------------------------------------------------------------------MDASRDIGSFVVWDYVVFAGMLLISAAIGIYYAFAGGGQQ------------------------TSKDFLMGGRSMSAVPVALSLTASFMSAVTVLGTPAEVYRFGAI--FSIFGVTYFFVVVISAEVFLPVFYRLGITSTYEYLELRFN--RFIRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFASVIIQASIT---QGGINTILSDASNGG------------------RLNFWNFNPNPLQRHTFWT-IIVGGTFTWTTIYGVNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILICSVFCGLALYSRY---------HDCDPWTSKKVSEVDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFK-SLSEKSLSWISQGMSVLYGALCIGMAAVASLMG-ALLQAALSIFGMVGGPLLGLFSLGILVPFANSVGAFAG--LLAGFAVSLWVGIGAQLYPPLPER-TLPLSLETHGCN----------STHNGTDWMSTTEMPFSTSAFQIHDVERSALMDNWYSLSYLYFSTIGTLTTLLVGILISLATGGRK-QNLDPRFLLTKQDFLSNFDVFKK-------------KTHVLN----YKMHP--------VEDGGTDNPAFNHVELNF--------------PDHSGKINGTRL----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92911-1", "uniprot_id": "SC5A5_HUMAN", "id": "Q92911-1", "name": "Sodium/iodide cotransporter", "aln": "------------------------------------------------------------------------------------------MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQR------------------------SAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSEAYRYGLK--FLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVML---VGGPRQVLTLAQNHS------------------RINLMDFNPDPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFY---------TDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLR-SLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAG--LGAGLALSLWVALGATLYPPSEQT-MRVLPSSAARCVALSV------NASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLW--WDLARQTASVAP-------------KEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63008-1", "uniprot_id": "SC5A5_RAT", "id": "Q63008-1", "name": "Sodium/iodide cotransporter", "aln": "------------------------------------------------------------------------------------------MEGAEAGARATFGAWDYGVFATMLLVSTGIGLWVGLARGGQR------------------------SADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLK--FLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFS--RAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVIL---LGGPRNVLSLAQNHS------------------RINLMDFDPDPRSRYTFWT-FIVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYY---------KDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMP-GLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSG--LAAGLAVSLWVAVGATLYPPGEQT-MGVLPTSAAGCT----------NDSVLLGPPG-ATNASNGIPSSGMDTGRPALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLW--WDLARQTASVAP-------------KEDTATLEESLVKGPEDIPAVTKKPPGLKPGAETHPLYLG---------------HD-----VETNL----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W3R0-1", "uniprot_id": "Q9W3R0_DROME", "id": "Q9W3R0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MHVEELRASLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANG---SEEAASSAA--------SYLVGGRQMKIFPITMSLISSFISGITLLGTPTEVYLYGAQ--YMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYN--RSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTLIMFGAMALVLIKGTLD---IGGPGVVWQKAQETA------------------RLEVPNFSADLSERYTFYS-LVLGGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATY---------SQCDPLETKLAQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALVFAVEKLG-AVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLG--GFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYSTMGCNYTFAGEPR----------------EFASLALDGAISSVPSAPFQLYRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTPFVRRWLER--RRHRR------------------SKIPDSGQK-------SSNKQETKT---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGP3-1", "uniprot_id": "Q9VGP3_DROME", "id": "Q9VGP3-1", "name": "", "aln": "----------------------------------------------------------------------------------------MSNIEEVLGELQRFAWPDYVAFVSMFLLCIGIGIYFGFMN-----------------KSVSED--------DYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYSYGIQ--YLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFD--RRLRLYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKGTRD---IGGAGVVLERAWSSD------------------RLEAPDLSIDPTVRHTFWC-LFFGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATY---------QNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVEHMG-TVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVG--GVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFN--------------------VTTSLANTTHLGASAEDIFPLYRISYMWYTTFGASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKFFAFGSEKHMD------------------AFRPDIPLQ-------HKLRNDEVAL--------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBK1-1", "uniprot_id": "Q9VBK1_DROME", "id": "Q9VBK1-1", "name": "", "aln": "MSTTADPVALGVNSPVEDVVAKTTTTVANAIAKTVAVISSTVSTSSTTGATSTISTSSSTPTTSTTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGK---DGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQ--YAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRFD--RRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLD---LGGLSVVLDHNRQYD------------------RLVGPDMTFDPTARMGVFA-LFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLLAFAEF---------YHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLG-LVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTG--ISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFD--------------------LPANWNATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVAS------------------EEKNNFNLH-------ESETQLKLEQP-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPY0-1", "uniprot_id": "Q8IPY0_DROME", "id": "Q8IPY0-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MDTYRFGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTP--TNEAPERRHQNFGSKKMNDYMMGSRNLRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQ--YCFIVIALVLQGLAVSYIYLPVFSALQVTSSYEYLEMRFH--SAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCY---IDDQADFLEGLVRGG------------------RLIFSETNPSPFARHTVWS-VVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAY---------RDCDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVS-GVLSISVSLAAIAASSTFGIFTVGMLVPWANTVGTAVG--GIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGC--------------------------LANASVAENAWVAEEEVFPLYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHRFLPKECFEQG-----------------------NAEEN-------SVKDNPLLF---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ85-1", "uniprot_id": "Q9VQ85_DROME", "id": "Q9VQ85-1", "name": "Sodium-coupled monocarboxylate transporter 1", "aln": "------------------------------------------------------------------------------------------------MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSP----ADTPEISIPNFGSKKMNEYLMGSGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQ--YSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYLGMRFH--PLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCY---ITDLDDFFESLVDGG------------------RLIFGNINPSPYVRNTVWS-VVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMY---------KDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVS-GILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVG--GIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASC--------------------------PGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQR-----------------------NLDKS-------EATDIYTIT---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLR8-1", "uniprot_id": "Q9VLR8_DROME", "id": "Q9VLR8-1", "name": "", "aln": "----------------------------------------------------------------------------------------MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQ--YWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEYLEMRFH--SVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVY---ANGLNVLFDDAAKGG------------------RLIFNNTNPSPYVRHTVWS-VLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMY---------KDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLS-GILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVG--GIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGC--------------------------VGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGR-----------------------NLHAQ-------AHKNLLNVS---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IN99-1", "uniprot_id": "Q8IN99_DROME", "id": "Q8IN99-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------------------------MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSE-------DNRRTNFGSEKIDEYLMGSRNMKVIPVSITLYR----VTSIIGTPSEIYHYGTQ--YYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLRFN--SIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYY---SNGLVAVFDDAEQGG------------------RLMLANTNPSPYVRHTVWS-VLIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKY---------KDCDPRSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQGILAFLIVFLLQHLR-GILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVG--GLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKEC--------------------------VGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGR-----------------------NLNER-------TEESLIQ-----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91659-1", "uniprot_id": "P91659_DROME", "id": "P91659-1", "name": "Sodium-coupled monocarboxylate transporter 2", "aln": "------------------------------------------------------------------------------MSTTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKN------------------------TTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFN--YIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFN--KRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIR---SGGMFTVMERASDGG------------------RFNFD-FGLDPRIRMTFWG-ATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARY---------YGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIR--HTEARANWAMKLIVVVMGGYCILGGFMVQNFN-SILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTS--IIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPV--TMKPPSGAP--VTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLPVTDQDL------------------EEVPLRGSKVAATPDLRIEPTEKEKQTVTEP---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9U2-1", "uniprot_id": "Q9V9U2_DROME", "id": "Q9V9U2-1", "name": "", "aln": "-----------------------------------------------------------------------------MASSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKN------------------------TTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFN--MIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFS--KRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGTSN---TGGITNVLENAAEGG------------------RFDFS-FGIDPRLRLTFIS-GMASGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYY---------YGCDPIQAGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRIN--HSEAKANATMKLVIVVMGAYCIVGGFIVQNFN-SIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSG--IAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLEL------------------EELPLK------TPLSEEQIKEKENGSATEA---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9U1-1", "uniprot_id": "Q9V9U1_DROME", "id": "Q9V9U1-1", "name": "", "aln": "------------------------------------------------------------------------------MSSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGED------------------------TTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPAEMYAYGIN--WVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFC--RKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVGVLGAHR---VGGFFEVLRIAGEGG------------------RLDIN-YNFDLTTRSTIWN-IFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRF---------HDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIR--HTEHRANVIMKLFVFFTGIYCILGGMVIENFN-SILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVG--VLASIACMATIVI-----LSWGRNHYDTLPTSTSACPAS-LNGTIKDIS---------TASPLFLGS--TTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFVHYKLTPSD-------------------EPHQLN-----------LEKPEKV----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ET37-1", "uniprot_id": "S5A4A_MOUSE", "id": "Q9ET37-1", "name": "Solute carrier family 5 member 4A", "aln": "------------------------------------------------------------------------------MASTASVSTSTASSELSSLSNNINNAADISVIVIYFVVVMAVGVWAMLKTNRST-------------------------VGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGAASGIA--VTAFESHSFALLLVLGWIFVPIYIKAGVMTMPEYLKKRFGGKRLQIYLSILFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQAVIMLVGSFILMVFAFVE---VGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFRDPVTGDIPWPGTAFGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPLFFMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPMLVLKLMP--MGLRGLMLSVMLASLMSSLTSVFNSASTLFTIDLYTKIRKKASERELLIAGRLFVSVLIVTSILWVPIVEVSQGGQLVHYTEAISSYLGPPIAAVFLVAVFCKRANEQGAFWG--LMVGLVMGLIRMIAEFSYGTGSCLAPSSCPKIICGVHY--------------LYFAIILFFVCILVILGVSYLTKPIPDVHLHRLCWALRNSKEERIDLDAEDKEENGADDRTEEDQTEKPRGCLKKTCDLFCGLQRAEFKLTKVEEEAL----TDTTEKPFWRTVMNVNVILLLAVAAFFYGYFA-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91ZP4-1", "uniprot_id": "S5A4B_MOUSE", "id": "Q91ZP4-1", "name": "Solute carrier family 5 member 4B", "aln": "------------------------------------------------------------------------------MASTLSPSITPQTEEPPVVPVRIQNAADISVIVIYFIVVLAVGLWSMVRSNRGT-------------------------VGGFFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIA--IAAVEWNALLMVLVLGWVFLPIYIKAGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAE---VGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLELMP--DGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMIAGRIFGMVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWG--LMVGLVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHY--------------MYFAIILFFVSIIVILGVSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEELETQEEAGGALEEDSEQSRGCLKRACCLLCGLQNTGPKLTKEEEAALRQKFSDTSEKPLWRTVMNINAVLLLGVAVFVHAYFA-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SWY8-1", "uniprot_id": "SC5AA_MOUSE", "id": "Q5SWY8-1", "name": "Sodium/mannose cotransporter SLC5A10", "aln": "------------------------------------------------------------------------------MAGNSTGDAHVPGSQLSVT--------DIIVISVYFALNVAVGIWSACRANKNT-------------------------VSGYFLAGRDMAWWPIGASLFASSEGSGLFVGLAGSGAAGGLA--VAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRFGGQRIRTYLSVLSLMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAVILAVKAFNQ---IGGYEQLEAAYAQAIPSRT-----IPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMP--IGLRGLMIAVMMAALLSSLTSIFNSSSTLFTMDIWRQLRPSAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFWG--LMAGLVVGALRLVLEFLYPEPPCGQIDTRPAPLRSLHY--------------LHFAIALFLLTCAVMAAGSLLSPPPQQRQIENLTWWTLAPN-------------WSLGTKTGDGQTPQKR--------------------------------------AFWARVCNVNAIFLMCVNIFFYAYFA-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33413-1", "uniprot_id": "DUR3_YEAST", "id": "P33413-1", "name": "Urea active transporter", "aln": "---------------------------------------------------------------------------------------------MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQK--------------------EIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYG--KIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDG-----------NYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPN--------FPTYPDPLTSFQANSGLVLPAAAIAIMGKGGAVASLLM--IFMAVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYTSHVACIFFGLAMSGFSVGLYYGG-ISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSP---AIFIPILTYVFKPQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLVSDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLCVFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIYTTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .. : : :: .: . * . . : . *: : . * . : **: .. ** : :. . . . . . : : . * . .: .::: . *: : : : . : * . . . . ", "identical_positions": 10, "similar_positions": 54, "identity": "1.14%" }, { "cls_id": "homologset.agr.SGD:S000001009", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7B6-1", "uniprot_id": "D4A7B6_RAT", "id": "D4A7B6-1", "name": "", "aln": "-MAAACRSMASLLPGLLCRLPAGAQMLRVALCLLCWVPAAVDAVPELGLWTRTVNDKSGPLIFRKTMFNSTDIRFSVKSFSCSGPVKFTIEWHLKYHT-CHNEYPELEEELFQKHELHADGD---VCAYFKNIDCWTTKSENLDCSSDS----QAFPSLNNKELTGIR----NISSQEGSMDVVARTQKDGFHIFIVSIKTEKTDAIWDLN-------VSLSMVGPHGYISASDWPLMIFYMVMCIVYILYGVLWLLWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNINSTG---LSTQGLLIFAELISALKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAIEGVMRVIGGSKH---LAVALTDIVLAVIDSISVWFIFISLAQTMKTLRLRKNTVKFSLYRHFTNTLIFAVLASIVFMVWTTKTFR----IAKCQSDWMELWVDDAFWS-FLFSLILIVIMFLWRPSANNQRYAFMPLIDDSD-DEVEEFMVTSENLTEGIKLRASK-TVSNGTAKP-TSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEIAEKMFSSEKIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKU8-1", "uniprot_id": "TM87B_MOUSE", "id": "Q8BKU8-1", "name": "Transmembrane protein 87B", "aln": "-MAAACRSEAGLLPSLLCRRPAGAQLLRVALCLLCWVPAAVDAVPELGLWTRTVNDKSGPLVFRKTMFNSTEIKFSVKSFSCSGPVKFTIEWHLKYHT-CHNDYPDLEEELSQRHELHADPD---VCAYFKNIDCWTTKSENLDCSSDS----QAFPSLNNKELTGIR----NISSQEGSTDVVARTQKDGFHIFIVSIKTEKTDAVWDLN-------VSLSMVGPHGYISASDWPLMIFYMVMCIVYILYGVLWLLWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNINSTG---LSTQGLLIFAELISAVKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAIEGVMRVIGGSKH---LAVVLTDIVLAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFTNTLIFAVLASIVFMVWTTKTFR----IAKCQSDWMELWVDDAFWS-FLFSVILIVIMFLWRPSANNQRYAFMPLIDDSD-DEVEEFMVTSENLTEGIKLRASK-TVSNGTAKP-TSDNFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEIAEKMFSSEKIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96K49-1", "uniprot_id": "TM87B_HUMAN", "id": "Q96K49-1", "name": "Transmembrane protein 87B", "aln": "-MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHT-CHNEHSNL-EELFQKHKLSVDED---FCHYLKNDNCWTTKNENLDCNSDS----QVFPSLNNKELINIR----NVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLN-------VSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTG---LSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNH---LAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFR----IAKCQSDWMERWVDDAFWS-FLFSLILIVIMFLWRPSANNQRYAFMPLIDDSD-DEIEEFMVTSENLTEGIKLRASK-SVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NBN3-1", "uniprot_id": "GPHCC_HUMAN", "id": "Q8NBN3-1", "name": "Golgi-pH regulating cation channel", "aln": "MAAAAWLQVLPVILLLLGAHPS-------PLSFFSAGPATVAAADRS-KWHIPIPSGKNYFSFGKILFRNTTIFLKFDGEPCD--LSLNITWYLKSAD-CYNEIYNFKAEEVELYLEKLKEKRGLSGKYQTSSKLFQNCSELFKTQTFSGDFMHRLPLLGEKQEAKENGTNLTFIGDKTAMHEPLQTWQDAPYIFIVHIGISSSKESSKENSLSNLFTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGMLEKAVFYAEFQNIRYKG---ESVQGALILAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVVAGALYLLFSGMEGVLRVTGAQTD---LAS-LAFIPLAFLDTALCWWIFISLTQTMKLLKLRRNIVKLSLYRHFTNTLILAVAASIVFIIWTTMKFR----IVTCQSDWRELWVDDAIWR-LLFSMILFVIMVLWRPSANNQRFAFSPLSEEEEEDEQKEPMLKES--FEGMKMRSTK-QEPNGNSKVNKAQ--EDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERSKME------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ34-1", "uniprot_id": "Q9VQ34_DROME", "id": "Q9VQ34-1", "name": "GOST seven transmembrane domain-containing protein", "aln": "-MQGSATLLVVALALLLG-------------------PASTAGKSDPGMVDVLVTTDLPSIREQRPLLANTKIYAQIKGCTSNVESNLTITFRLTEHP-CIFDDRTLQAIAQNATLQKNATINNVITEITRTYPCNGLIVLAINKDKVVEG--SAIPTPEPKHPMLEH-----KHPLSPTTNPIASVKEDGIYEIEVNIAAGPSAQFSAVV--------HIEFLGPHGFISAIDWPFLPFYLIMCIVYVIFGIIWLFVSFAQWRDLLRIQFWIGGVILLGMLEKAFFYAEYQTLTNKG---VAVQHAELVAEFVSCAKRTLARMLVIIMSLGFGIVKPRLGPMLHRVVGVGTLYFVLACVESYLRITNVKTDR--SELLVASIPLAVLDTGICWWIFTSLVQTTRTLRLRRNMVKLSLYRHFTNTLIFAVIASVIFMLFALRLRR----VENCTPGWRDIWVDTGFWH-ILFSVLLLVIMILWRPTNNNQRYAFTPLLDNPEDEDDEDEEDQFVADAYGVKMRGQNGTPKTSTTSRNATTTEEDDLRWVEENIPSSMADSALP-ILDSDEEIINTKFEVSKMQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38745-1", "uniprot_id": "YHB7_YEAST", "id": "P38745-1", "name": "Uncharacterized membrane protein YHL071W", "aln": "--MDRTWLLLTWLLLLCG---------------------VVQGNQES------INQKYHDVCSG--MYSKEDFNGKVDPYISFTLEELSLADEDDDGEGVSVAVFDFQDYEHIGVRLPNGEIQYICDDYALDLGLCEDSSEGQFIIQET-----AIDPFTSKEHKLTSQILTFTQQELGTNDKVYSINKTGYYCVTTSSFISSSSKFKATVN----------FRNAYGQLDASEAYKMPIYAFLAVAYAVCTLVYSWLCWKHRHELLPLQRYILVFCIFLTADTIFVWMYYIIENQKGNSSVALHVYMVFISIFSAGKMTFTLLLALLISLGYGIVYPKLDRTLLRRCQIFAIFTFAVCVAFLVQKYSQNSESLSNLILITAIPLVLCLFAFYYLTLSSMNKTMTYLREQNQVVKLNMYRKLIILCYISLFILFLGLLVSTFAYVGMDTVDMIEQYWKTEFLITDTWPSFVYFLVFVIFAFFWRPTSTSYLLACSHQL-PTDMENVSEFDLDDINSLSDEALPNRE--PRNDYQEHDHNMDIDLASDFEEVPSVNANTNANNDVLFDVDYDRDAKNDRSTT--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : . : ... . .:.: : : *. : . : . : . . : . ..: : : : :: .:.:.* : ::: . :::* :* :* . :: :. ..: : .* : : :. .:.*. * ::: *.:::***:*** *:*. : : :: . : :: . ... : * *.. : : *: :* *: :.: **:.:**:: ::: .: : : : * :: * ::: :::.:: .:***: .. * : :: .: . : : .. . : : * .: :: :.* * : . ", "identical_positions": 35, "similar_positions": 152, "identity": "5.94%" }, { "cls_id": "homologset.agr.SGD:S000001010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61457-1", "uniprot_id": "PHS_HUMAN", "id": "P61457-1", "name": "Pterin-4-alpha-carbinolamine dehydratase", "aln": "------------------------------------------------------------------------------------MAGKAH----RLSAEERDQLLPNLR--AVGWN-ELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAG-------LSERDINLASFIEQVAVSMT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61459-1", "uniprot_id": "PHS_RAT", "id": "P61459-1", "name": "Pterin-4-alpha-carbinolamine dehydratase", "aln": "------------------------------------------------------------------------------------MAGKAH----RLSAEERDQLLPNLR--AVGWN-ELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAG-------LSERDINLASFIEQVAVSMT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61458-1", "uniprot_id": "PHS_MOUSE", "id": "P61458-1", "name": "Pterin-4-alpha-carbinolamine dehydratase", "aln": "------------------------------------------------------------------------------------MAGKAH----RLSAEERDQLLPNLR--AVGWN-EVEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAG-------LSERDINLASFIEQVAVSMT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CZL5-1", "uniprot_id": "PHS2_MOUSE", "id": "Q9CZL5-1", "name": "Pterin-4-alpha-carbinolamine dehydratase 2", "aln": "---------------------------------------------------MVAAAAVAVAAVGARSAGRWLAALRSPGASRAAMSSDAQ----WLTAEERDQLIPGLK--AAGWS-ELSERDAIYKEFSFKNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGG-------LTKRDVKLAQFIEKAAASL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0N5-1", "uniprot_id": "PHS2_HUMAN", "id": "Q9H0N5-1", "name": "Pterin-4-alpha-carbinolamine dehydratase 2", "aln": "-------------------------------------------------------MAAVLGALGAT--RRLLAALRGQSLGLAAMSSGTH----RLTAEERNQAILDLK--AAGWS-ELSERDAIYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGE-------LTKKDVKLAKFIEKAAASV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76454-1", "uniprot_id": "PHS_DROME", "id": "O76454-1", "name": "Pterin-4-alpha-carbinolamine dehydratase", "aln": "MLLTIKCAQNVIKPNCQKVANLLASSRRAGLFPTTATTATSRSLSQISVLYSPAAREAARAATGGSANLRRIHNTPTTEATATAITAKKRKMVVRLNEQERAEKLQPLL--DAGWT-LVEGRDAIFKQFVLKDFNQAFSFMTGVALLAEKINHHPEWFNCYNKVDVTLSTHDVGG-------LSSQDIRMATHLETTANLLK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38744-1", "uniprot_id": "PHS_YEAST", "id": "P38744-1", "name": "Putative pterin-4-alpha-carbinolamine dehydratase", "aln": "-------------------------------------------------------------------------------MHNKIVRIASS----ALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITREVTFKDYETTWAFLTRVSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSDIDVRMAKRIDSYIDEMTT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : : : * . * .* ::. ::::: ::.*:: *:: :. .*** .. *. *.: * :*: *:. *:.:* :: : ", "identical_positions": 16, "similar_positions": 40, "identity": "7.88%" }, { "cls_id": "homologset.agr.SGD:S000001011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35585-1", "uniprot_id": "AP1M1_MOUSE", "id": "P35585-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATS----KKNACVSLVFSFLYKVVQVFSEYFKELEEES--IRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEG-----------------------------------------------------------------------------------HKLETGAPRPPATVTN-----------------AVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVG-SIKMRVFLSGMPELRLGLN-----------DKVLFDNTGRGKSKSVELEDVKFHQCVR-LSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIES----VIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVP--------NDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAED-------------------------------------------------------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32Q06-1", "uniprot_id": "AP1M1_RAT", "id": "Q32Q06-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATS----KKNACVSLVFSFLYKVVQVFSEYFKELEEES--IRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEG-----------------------------------------------------------------------------------HKLETGAPRPPATVTN-----------------AVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVG-SIKMRVFLSGMPELRLGLN-----------DKVLFDNTGRGKSKSVELEDVKFHQCVR-LSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIES----VIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVP--------NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAED-------------------------------------------------------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXS5-1", "uniprot_id": "AP1M1_HUMAN", "id": "Q9BXS5-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATS----KKNACVSLVFSFLYKVVQVFSEYFKELEEES--IRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEG-----------------------------------------------------------------------------------HKLETGAPRPPATVTN-----------------AVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVG-SIKMRVFLSGMPELRLGLN-----------DKVLFDNTGRGKSKSVELEDVKFHQCVR-LSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIES----VIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVP--------NDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAED-------------------------------------------------------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O62531-1", "uniprot_id": "O62531_DROME", "id": "O62531-1", "name": "", "aln": "MSSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNNLYIVSTTPR--NKNVNIALVFVFLHKIAQVFVEYFKELEEES--IRDNFVIIYELLDELLDFGYPQTTDSKILQEYITQEG-----------------------------------------------------------------------------------HKLEL-QPRIPVAVTN-----------------AVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEIVG-AIKMRVYLSGMPELRLGLN-----------DKVLFESTGRGKSKSVELEDVKFHQCVR-LSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIES----VIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVP--------ADADSPKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDN------------------------------------------------------TEGKPPIQVRFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLRTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9WVP1-1", "uniprot_id": "AP1M2_MOUSE", "id": "Q9WVP1-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VPMTEIDHFMPLLMQREEEGVLAPLLSHGRVHFLWIKHSNLYLVATT----LKNANASLVYSFLYKTVEVFCEYFKELEEES--IRDNFVIVYDLLDELMDFGFPQTTDSKILQEYITQQG-----------------------------------------------------------------------------------NKLETGKSRVPPTVTN-----------------AVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVG-TIKLKVFLSGMPELRLGLN-----------DRVLFELTGRSKNKSVELEDVKFHQCVR-LSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIES----VIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVP--------SDADSPRFKTSVGSAKYVPEKNVVIWSIKSFPGGKEYLMRAHFGLPSVETEE-------------------------------------------------------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGDYQLRTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRP6-1", "uniprot_id": "AP1M2_RAT", "id": "D3ZRP6-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VPMTEIDHFMPLLMQREEEGMLAPLLSHGRVHFLWIKHSNLYLVATT----LKNANASLVYSFLYKTVEVFCEYFKELEEES--IRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQG-----------------------------------------------------------------------------------NKLETGKSRVPPTVTN-----------------AVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVG-TIKLKVFLSGMPELRLGLN-----------DRVLFELTGRSKNKSVELEDVKFHQCVR-LSRFDNDRTISFIPPDGDFELMSYRLSTQVRPRVDXES----VIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVP--------SDADSPRFKTSVGSAKYVPEKNVVIWSIKSFPGGKEYLMRAHFGLPSVETEE-------------------------------------------------------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGDYQLRTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6Q5-1", "uniprot_id": "AP1M2_HUMAN", "id": "Q9Y6Q5-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHSNLYLVATT----SKNANASLVYSFLYKTIEVFCEYFKELEEES--IRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQS-----------------------------------------------------------------------------------NKLETGKSRVPPTVTN-----------------AVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVG-TIKLKVFLSGMPELRLGLN-----------DRVLFELTGRSKNKSVELEDVKFHQCVR-LSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIES----VIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVP--------SDADSPRFKTSVGSAKYVPERNVVIWSIKSFPGGKEYLMRAHFGLPSVEKEE-------------------------------------------------------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGDYQLRTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q618-1", "uniprot_id": "A0A8M9Q618_DANRE", "id": "A0A8M9Q618-1", "name": "", "aln": "MAASAIFILDLKGKVLICRNYMGN-IDMNVIDNFMPIMMKREEEAELSPVVIHGSTHFLWIKHSNLYLVAMT----KKNTNAALVYSFLYKLVEVFTEYFKSLEEES--IRDNFVTVYELMDEVMDFGFPQTTDSKILLEYITQQG-----------------------------------------------------------------------------------HKLEVGAPRPPATVTN-----------------AVSWRSEGIKYRKNEVFMDVIESVNLLVSATGSVLRSEILG-CIKLKVVLSGMPELRLGLN-----------DKVLFEITGREKTKSVELEDVKFHQCVR-LSRFENDRTISFIPPDGESELMSYRLNTTVKPLIWIES----VIEKFSHSRVEIKVKARSQFKSRSTANNVSILVPVP--------SDADSPKFKTTTGQAKWVPEKSAVEWNIKSFPGGKEFMMRAHFGLPSVESDE-------------------------------------------------------LEGKRPITVKFEIPYFTVSGIQVRYLKIIE-KSGYQALPWVRYITQSGDYQLRTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38700-1", "uniprot_id": "APM2_YEAST", "id": "P38700-1", "name": "Adaptin medium chain homolog APM2", "aln": "-MSSSLFILDENLEPLVSKNIRALPNLSSVLSSFKQCYHDGS-----PPILSQNDWFFIHLKRDFLHFVSVIHTTDKPNIDLMTILAFLEQFYHLLQKYFEIEVLTKNVILDNILLVLELIDECIDFGIVQVTDPSIIKDYIRVKVNVPRVTVDNEEWSPGEESSSSSGSDSDSEYSNTNKRKDKKKKRKKKKGTKGKSVGKSKLKSIMVNNKENRGINVVETVKETLRNKNDTGKEAANDELPNDGNDLYINGDIAKTIIMPISWRTKGIHYAKNEFFLDVIERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISINKILNRDPQFMSNSSFHQCVSLDSINTIEKDEEKNSDDDAGLQAATDAREIEFIPPDGEFVLCQYELKRHVKDAPMVRLKDFEIKPKLKKFKIQIVTKIQTNFKPTNSTSKLNVRIPLTKVFQEYKIDLSKQIRFKANIGKVVFNLSDDFLLWEIQTMKGHREHSTNKSSQYNSDEDDPNTCASMVAEFPLFNQEEYDRLQEEMKTSMNPPPLRTGPRLEELYRQVHDQQTSHVTPRDKLVNIDFEIPYCTCSGLKVEYLKVEEPQLQYQSFPWVRYKTVSDEEYAYIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::::** : : *:.:* . :. * . . .*:: * :* . *::*: * : ** : .:: :**: . * **:: : :*:** :*** *.**..*: :** : :* : :.* .:***::**:* ***.*:**** *: * . .*: .::: * : *****:*::.:* : :.: .. . :::* :: * : *. : * *.******: * .*.*. *: . : : : ::: * : :** . :. :.: :*:. :.. :**:. *. : . . : * :::: * :*. . * * : : : ***** * **::*.*:*: * : **::***** * ..: ", "identical_positions": 105, "similar_positions": 139, "identity": "17.18%" }, { "cls_id": "homologset.agr.SGD:S000001013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZE0-1", "uniprot_id": "TMLH_MOUSE", "id": "Q91ZE0-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "----MWYHKLLHQQSRLRNLMKRGNIAQGLHLSNFKSLFSSSIHWCHTTSKSVNCTWHQHEDHLELQYAGTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTVHLDET--MLFFTWPDGHVTRYDLDWLVKNSYEGQKQKVIQPRILWNSKLYQQ--------AQVPSVDFQCFLE--TNEGLKKFLQNFLLYGIAFVENVPPTEEH---TEKLAERISLIRETIYGR-MWYFTS-DFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGT-GGRTL----LVDGFYAAQQVLQKAPEEFELLSKVPLKHEYIENVG--QCHNHMIGVGPI----LNIYPWNKELYLIRYN------------NYDRAVINTVPYDVVHR------------WYTAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTG----YRQLCGCYLTRDDVLNTARLLGLHA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91ZW6-1", "uniprot_id": "TMLH_RAT", "id": "Q91ZW6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "----MWYHKLLHQQSRLQNLMKRGDIAHGLRLSGFKSLFPFSLHWCHTASKSVNCTWHQHEDHLELQYASTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDES--TLFFTWPDGHVTRYDLDWLVKNSYEGQKQEVIQPRVLWNAKLYQD--------AQLPSVDFQGFLE--TKEGLKKFLQNFLLYGIAFVENVPPTQEH---TEKLARRVSLIRETIYGR-MWYFTS-DFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGT-GGRTL----LVDGFYAAQQVLQRAPEEFDLLSQVPLKHEYIENVG--QCHNHMIGVGPI----LNIYPWNKELYLIRYN------------NYDRAVINTVPYDVVRR------------WYAAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTG----YRQLCGCYLTRDDVLNTARILGLHA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVH6-1", "uniprot_id": "TMLH_HUMAN", "id": "Q9NVH6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "----MWYHRLSHLHSRLQDLLKGGVIYPALPQPNFKSLLPLAVHWHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDET--TLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIYQQ--------AQVPSVDCQSFLE--TNEGLKKFLQNFLLYGIAFVENVPPTQEH---TEKLAERISLIRETIYGR-MWYFTS-DFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGT-GGRTL----LVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVG--ECHNHMIGIGPV----LNIYPWNKELYLIRYN------------NYDRAVINTVPYDVVHR------------WYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTG----YRQLCGCYLTRDDVLNTARLLGLQA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5B5-1", "uniprot_id": "Q9W5B5_DROME", "id": "Q9W5B5-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "--------------------------MLSCRQLISRLSLLRQASTFACVR------LCPDYVEVQ-EEQGNLLKYPQVWLRDNCQCAECFHAATRARKSHWDRGPLNIPVSQVAYNKERKQLEIIWQDKHRSTFDLGWLRERDFGETGRKHYLEEVYKPPAQLWGK---TEFEDVKREFQYEDVLE--QDAALRVWLEALAVQGFAILKGAPNDINV---AKKLAERIGYIKRTTYGD-VFEVKS-KPNARNYAYLMTPLPLHTDMPYYEYKAGINILHTLVQSESKGGANT----LTDGFNVASQLQKLHPEDFEVLKSVPVNWFDIGHDGDDSKPFHSLWRAPV----ICLD-VDGRFARINQN------------TTKRDSRFSVSLAQAVS------------WYKAYDKFLEIAQSEA--VEFKTQAGDVFVFNNLRMLHGRTAYEDAPGNKRHLVGAYVDWDIIYSKLRTLKFPNAKD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY24-1", "uniprot_id": "Q9VY24_DROME", "id": "Q9VY24-1", "name": "", "aln": "--------------------------MWVPRLLGRSLSQLKTINSAQFSRQISAKIVNESSIEVQPEANSKPLTFPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWLKERCFEPDKQQEYLRDFYRPTTRHWSG---AEFQDIAQHFSYDEVMS--QDSVLMQWLQALAIYGVALLRGAPLDEGV---VRRLADRVGFIRRTTYGE-EFVVQA-KPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILHCVVQTDSPGGSNM----LVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSE--DGREFHNIWRAPV----ICLD-EEGRYTRINHS------------VPQRDSHFNVPLEEVLP------------WYESYALFVRLAIADS--HAFKTRPGDVLTFNNIRLLHGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLKKRLTASCQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q924Y0-1", "uniprot_id": "BODG_MOUSE", "id": "Q924Y0-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MHCA----------ILKAEAVDGAHLMQIFWHDGAESLYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRIDDLTFDR--KKVYITWPNDHYSEFEANWLKKRCFSQQARARLQGELFLPECQYWG------SELQLPTLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIGVD---YCDFSVQSKHKI----IELD-DKGQVVRVNFN------------NATRDTVFDVPIERVQP------------FYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZU7-1", "uniprot_id": "BODG_RAT", "id": "Q9QZU7-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MHCA----------ILKAEAVDGARLMQIFWHDGAESLYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRMDDLTFDQ--KKVYITWPNGHYSEFEANWLKKRCFSQEARAGLQGELFLPECQYWG------SELQLPTLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKEKNPQAFSILSSTFVDFTDIGVD---YCDFSVQSKHKI----IELD-DKGQVVRINFN------------NATRDTVFDVPIERVQP------------FYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVMNGN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75936-1", "uniprot_id": "BODG_HUMAN", "id": "O75936-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MACT----------IQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDR--KKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWG------SELQLPTLDFEDVLR--YDEHAYKWLSTLKKVGIVRLTGASDKPGE---VSKLGKRMGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVD---YCDFSVQSKHKI----IELD-DKGQVVRINFN------------NATRDTIFDVPVERVQP------------FYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D5NSC9-1", "uniprot_id": "A0A1D5NSC9_DANRE", "id": "A0A1D5NSC9-1", "name": "gamma-butyrobetaine dioxygenase", "aln": "MLSYLARWVSRGAVQALKGTSSRPQLVKTPRIGNQTLAAAPLPFAGGSPGVRQARALDQERLLQIDWDDGSCSLYPFTWLRDNCQCPLCTLQSAQARSLLFSHLDVHTGMDHVQLMD--NKVSITWPDQHSSEFDPDWLKKRCFSSEARQALQEELFLNEREYWD------SGLQIPTADFEEVLH--DDKAALAWLEALRRIGIVYLRGAPAEQGQ---LARLSQRIGYLRLTFYGH-TWQVQD-KPMANNVAYTSGELSLHTDYPALHHPPGVQFLHCVRQADE-GGESE----VVDGFHMAEQLRREDPEAFNILSSLRVDFTDSGAD---YCDFSVQSKNHI----IDVD-SSGRVVRINYN------------NATRDSVLDLPLHQVQP------------FYSSLKAFVELLSRPENVFTYRMEPGDVVTFDNWRLLHGRKSYQSRGQNLRHLEGAYLDWDEVMSRLRILRKTVRGDS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23180-1", "uniprot_id": "AIM17_YEAST", "id": "P23180-1", "name": "Probable oxidoreductase AIM17", "aln": "-----------MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNRDSTTITFSMEESSKPVSVCFNNVFLRDASHSAKLVTTG------ELYHNEKLTAPQDIQISEDGKSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLLSVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTVHGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRPMNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGDKRYYQSKPLIEHHDINEDNTLLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFIRGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHANSLTSS---NQQWLKGCYFDSDTFKSKLKFLEEKFPHDK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*** . . : : . * : : :: . . : .: . * : *.. : ... :: *:. : * :* : . . : * * *** . . ..:.:: : . . ..*.* : . : : *. :. : : . :. . : : . : : . . ::* *:**.. : : *.* * . . : * ", "identical_positions": 25, "similar_positions": 79, "identity": "5.14%" }, { "cls_id": "homologset.agr.SGD:S000001014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8A8-1", "uniprot_id": "D3Z8A8_RAT", "id": "D3Z8A8-1", "name": "Meiotic recombination protein SPO11", "aln": "MALAPMGPEASFFDALDRHRASLLAMVKKGAGETPDRATRVPSSSEVLTSIENIIQDIIKSLARNEAPAFTIDNRSSWENMTFEDAFGLQMRPQCTTRKIKSDSLRSVRKFALILKILSMIYKLIQSNTYATKRDIYYTESQLFRNQAAVDSIIDDISCMLKVPRR-SLHVISTSKGLIAG--------NLRYVEEDGTQVQCMCSATATAVP---SNIQGMQNLVTDAKFLLIVEKDATFQRLLDDNFCSRMSP-CIMVTGKGTPDLNTRLLVKKLWD---TFHIPVFTLVDADPYGIEIMCIYKYGSMSMSFEAHNLTVPTIRWLGLLPSDIKRLNIPKDSLIPLTRRDQMKLDSILRRPYITYHPFWKKEMEMLADSKTKAEIQALSFLSSDYLSRVYLPNKLRFGGWI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTK8-1", "uniprot_id": "SPO11_MOUSE", "id": "Q9WTK8-1", "name": "Meiotic recombination protein SPO11", "aln": "MAFAPMGPEASFFDALDRHRASLLAMVKRGAGETPAGATRVASSSEVLTAIENIIQDIIKSLARNEVPAFTIDNRSSWENIMFDDSVGLRMIPQCTTRKIRSDSPKSVKKFALILKVLSMIYKLIQSDTYATKRDIYYTDSQLFGNQAAVDSAIDDISCMLKVPRR-SLHVLSTSKGLIAG--------NLRYMEEDGTRVQCTCSATATAVP---TNIQGMQHLITDAKFLLIVEKDATFQRLLDDNFCSRMSP-CIMVTGKGVPDLNTRLLVKKLWD---TFHIPVFTLVDADPYGIEIMCIYKYGSMSMSFEAHNLTIPTIRWLGLLPSDIQRLNIPKDSLIPLTKHDQMKLDSILKRPYITYQPLWKKELEMMADSKMKAEIQALTLLSSDYLSRVYLPNKLRFGGWI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5K1-1", "uniprot_id": "SPO11_HUMAN", "id": "Q9Y5K1-1", "name": "Meiotic recombination protein SPO11", "aln": "MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRR-SLHILSTSKGLIAG--------NLRYIEEDGTKVNCTCGATAVAVP---SNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSP-CIMITGKGVPDLNTRLLVKKLWD---TFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KPA5-1", "uniprot_id": "SPO11_DROME", "id": "Q7KPA5-1", "name": "Meiotic recombination protein W68", "aln": "-------------------------------------------MDEFSENIERIALELLSNLVHGNATLSVPRNSS--------------GNVISEYRRVSYNNRGSRHSFCVLIYMLSRVHRLQVRGGSFTVRGLYYDNPLLVRSQSRIAEARLDVCRMLRTSPL-SLGILAASKGLVAG--------DLRLLMTNGDVLDSSLYGGPLTLP---TDPEKIDRIETLAEFVLIVEKESVFESLLSRNVFGTFERRFILITGKGYPDCCTRRIVHRLTE---ENQLAAYILVDADPFGVEIMLVYRHGSKSMSFSSQGLTTPALRWIGLHPSEIPALGTG---AVALVAGDNKKINDLLAR--HDLEPGVRQELRMLQDVQLKAEIESV----IDFLTDDYIPNKINRNLFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23179-1", "uniprot_id": "SPO11_YEAST", "id": "P23179-1", "name": "Meiosis-specific protein SPO11", "aln": "MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTP--CSNADVLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQFK-LKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKLSPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAVIKLGTTSMCNIVIVEKEAVFTKLVNN--YHKLSTNTMLITGKGFPDFLTRLFLKKLEQYCSKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIRITQVLAQNNEVHNKS-IQLLSLNQRDYSLAKNLIAS---LTANSWDIATSPLKNVIIECQREIFFQKKAEMNEIDARIFEYK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *:.: ..* : : . : . :: .. : .::: :*. : . . * *.::* : *. *: : . : :: . ** ::.:.***: . :: : . : : : * ::****::.* *:. :. :::**** ** ** ::::* : :.****.*:.* * :.. :: . . :* : ..: . :.* * ..:: : : :.: : . : : . ", "identical_positions": 39, "similar_positions": 103, "identity": "9.47%" }, { "cls_id": "homologset.agr.SGD:S000001015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AV56-1", "uniprot_id": "A0A8I6AV56_RAT", "id": "A0A8I6AV56-1", "name": "GATOR complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTNKPRSR----YAVNNTGEHVDDQD--GDSSK------PCPPTDEQLVAGFSDAILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQVSKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHTLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADANEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAVIIYPLCENNVYVLSPNASVC----------------------------------LYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRPREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIJ8-1", "uniprot_id": "NPRL3_MOUSE", "id": "Q8VIJ8-1", "name": "GATOR1 complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTNKPRSR----YAVNNTGEHADDQD--GDSR-------------------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQVSKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADANEGPQSPFQHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAVIIYPLCENNVYVMSPNASVC----------------------------------LYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRLREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12980-1", "uniprot_id": "NPRL3_HUMAN", "id": "Q12980-1", "name": "GATOR1 complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTSKPRSR----YAASNTGDHADEQD--GDSR-------------------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQISKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADGNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAIIIYPLCENNVYMLSPNASVC----------------------------------LYSPLAEQFSHQFPSHDLPSVLAKFSLPVSLSEFRNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRPREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNQRMTENLLASLSEHERAAILSVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUB4-1", "uniprot_id": "NPRL3_DROME", "id": "Q9VUB4-1", "name": "GATOR complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METNVNPLAVILVYFDS--------------------------------------------KGDRLLYRYP---------------------------------------------YQTLGQTEVANDEQRKSRKRNPYAVANTDDLLQTPTHLGAAK------------SQGQLQGFADEVLSALFAVKPQLCNQKFELKLNDVRFVSHPTLIP---------------------------------------------------------QKE---QRSGPM----------------AKQ----QMLINIVFALH---AQASYSIVKCYHELSKRLGLALKFEEQRSGYLTEQTAQMARTHD-------EQQQQP-----LERTLELIAERCSLAQALRSIFHDLCTTGLLSTSLNHNLTLCFCLPAKAHQLHKK-------------GSMVDPETIDRCLRALKP------------------------------------------------------YHGMLLLVDFAELLDCVPPTGARMLWQLVDVYDPLISLQS------------------------MSSNADLSIEHVYKLVSHLVYWAKATIIYPLCETNVYVIAPDAPLH----------------------------------TKSHLVEKFSARFAGMSLFEVISDFSLPTSIGHLTTPLQQPARQGILAQMVIWMLQHHLLMQLHTYVQFMPSEDEFGDSASCSNHLRDAISDEEGDQEPDADELHGSMLSMSSHPLPVPAVLVGGHRREASEDHSSLASDNIAVQPSSSHKSNFSITASMSTDNCDSLDSMEDEQKLKELLQVFSDADRAAIRRIPASANVDDLSLLVKLYQMGYFKSEHHLEEIMYFENLRRS--QLLQLLDKFRDVLIIYETEDPAIASMYNTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38742-1", "uniprot_id": "NPR3_YEAST", "id": "P38742-1", "name": "Nitrogen permease regulator 3", "aln": "MDECLPNSCLLGVHLVISTHSGPQIVYHYPPSNTAFLTNNPTKHQHLYGNHANLNKNTSTNKEEKLFNSGSTKTASQIALNESAKSYNTAITPSMTNTNTNNVTLPPTRSHANTVGSQSSIPAATNGVGYRKTDIEDTSRTFQYQETESETSSSGLSDSELSTDYLDISSDSFSISSSLSSSSLSSSPSSSSSSSPPQDGLSRTNSSFQSTDSMSPTSPQMIMENDSISVAESYLDSGTNNKSRAASKRSQNFFHKLSTKKSTDSKTHSPVRKLKSKPSQSTKKGNKLLKNTSNETDGNAFTGSCSISSKKSLSSTGEHNQELRNSSLNDTPGQSPHHYHHRYHHYHKNAATSQRNSHTQYDVEEEDMEVSAMLQDGKISMNEIFFEEENFQDINKILEFDNDFVAEFCSPEREMCNTRFEFTVDNFCFLGLPIHVDSQGRWRKSKHKNKTRSKRSSSTTTNISRKKSIASKISSLSENTLKKVNSGEADTVYDSNIGHEASTDTPNLRINTDVSGNEFEREKEDLGKNMNMFHVCFVMNPHLIEYNKRIDDMYQFVVTRLSLLLRYVQSKTSYISSECHIILKEKERVLKHSKTYQSIRGAGNKGKYLYQRILAKSSLARALTECVDKIQRNEIACLEINDDKVISLQIPIQNEFEKMPNFKLQPVLRGSYLTSILNMKFLEKSSLRIESQNRQNDQAQFSDTNNNIYRFGNNINSTGHCGAANVDDGDDNESNYYCDDNDDLLNYALLLLDEPNNIISSLETFSYQDDIGTIILKHLVRNIQPNIPLRSYRYLITDLLDNPSSLDDLTTETNSLESSILRSCALHLMYWRHARIVIPLSSKYTYIVSPLAPIQGYTIDDYKSTSQNDGNVKKMDDRENNKSGSDRVPLIYQNSMLFRSKFPSLPSLPIFLSLLSTDKPQAYSNIIPSREHKPVYLNALAWLIQYGYVTQLLTFINIRVDK--------HIKMAVDEDLEKEGFRKTNTARRPSMDYKKTDKKLDDEDGQSRDAN------ASEACSGKNEGMQSNDNNKDVDEKDNENDSRVDDRDDNEIAIADEEEILHFEYDDPEMQHDYTIILEPERATAIEKRWLYRCIYGQPSDIQILFNKLLKYFNGKVPMELVIIKEEISRHDLKKLLNALDKYLIEIHHW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:: : .: :*::** . . :: . : : . * . : . . * * : .:: : : : ::*. :**:.:::. *:. * : :.. : :::: *.:. : . : . : : *:. *:. : : *:: : : :: . : . * :..**: * . ..: . : :* :.: :* : . *:: : :::. :.. :.:*** : .::. : : : .:* :. .* : . . **:** :* *: **... .*:::* *.: * :*.. :: .: . . . : :: : : *::* : ** *:: : . ::* . .: * . * .*.. .. .:. . . . *. :: : :. : . : : : : : .. :*:: : : :: : ::. : :. * ", "identical_positions": 53, "similar_positions": 200, "identity": "4.57%" }, { "cls_id": "homologset.agr.SGD:S000001019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01713-1", "uniprot_id": "KLF9_RAT", "id": "Q01713-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGGAPDAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGS--APSPLSLLHSGVASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTDFHPSMIKR----------SKKALASPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35739-1", "uniprot_id": "KLF9_MOUSE", "id": "O35739-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGGAPEAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGS--APSPLSLLHSGVASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTVFHPSMIKR----------SKKALACPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13886-1", "uniprot_id": "KLF9_HUMAN", "id": "Q13886-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGVAPDAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPEERQDPGS--APSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKR----------SKKALANAL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33400-1", "uniprot_id": "PACC_YEAST", "id": "P33400-1", "name": "pH-response transcription factor pacC/RIM101", "aln": "MVPLEDLLNKENGTAAPQHSRESIVENGTDVSNVTKKDGLPSPNLSKRSSDCSKRPRIRCTTEAIGLNGQEDERMSPGSTSSSCLPYHSTSHLNTPP-YDLLGASAVSPTTSSSSDSSSSSPLAQAHNPAGDDDDADNDGDSEDITLYCKWDNCGMIFNQPELLYNHLCHDHVGRKSHKNLQLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCSKKFKRPQDLKKHLKIHLESGGILKRKRGPKWGSKRTSKKNKSCASDAVSSCSASVPSAIAGSFKSHSTSPQILPPLPVGISQHLPSQQQQRAISLNQLCSDELSQYKPVYSPQLSARLQTILPPLYYNNGSTVSQGANSRSMNVYEDGCSNKTIANATQFFTKLSRNMTNNYILQQSGGSTESSSSSGRIPVAQTSYVQPPNAPSYQSVQGGSSISATANTATYVPVRLAKYPTGPSLTEHLPPLHSNTAGGVFNRQSQYAMPHYPSVRAAPSYSSSGCSILPPLQSKIPMLPSRRTMAGGTSLKPNWEFSLNQKSCTNDIIMSKLAIEEVDDESEIEDDFVEMLGIVNIIKDYLLCCVMEDLDDEESEDKDEENAFLQESLEKLSLQNQMGTNSVRILTKYPKILV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .. .* :: *:* . : **. :::*. .* .. : ** :*. . : :: * .*.* * .:.. : . *: *. **: *... ....* * : . . . * :. .:.: * :..** ::.:.. * * . * : * * ** .* .: *.:* * *.*. * * *. *.*:* *.:.*.** : * : :: *** : . ", "identical_positions": 53, "similar_positions": 84, "identity": "8.47%" }, { "cls_id": "homologset.agr.SGD:S000001022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDI5-2", "uniprot_id": "ECM29_MOUSE", "id": "Q6PDI5-2", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "-------------------------------------MYHIDCR--------DQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSAS---PFNLAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSSSQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKS------KQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICLTCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNKKESASKQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRALMSSSQATASSSNKSGETNPVQIYTGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMSSSKEEMRELAALFYS--VVVSTVSGIELKSMIEQLIKATKDNHSPEVQHGSLLALGFTVGRYLAKKRVRMAEQ---------HDLETDADLLPEQEEIIRSATETIGSFLDSTSPLLAIAACTALGEIGRNG---PLPIPSEGSGFTKLHLVES------LLNRIPSSKETNKMKERAIQTLGYFPVGDGVFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTNSVAARDAWLVT-EEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHREVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKR---------VKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLRG------RPLDDVIDKLP---------------EMWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGA---AGQRTIAVLLPCLLD-KGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLS--LRATEQEKDVMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYME-KDEPVYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASISKQTSS-LVPPYLGMILSALMQGLAGRTWAGKEELLKAIACVVTACSTELEKSVPNQPTTNEILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVIPLIKKNSLESMG-------VRTTKAEDENEKERELQLESLLGAFESLGKAWPRN-PDTQRCYRQELCKLMCERLRLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCKSITYSLENKTYSSVRTEALSVVELLLKKLEEAKQWESLTAECRGLLIES-LATMETDNRPELQEKASVLKKTLESLE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A123-1", "uniprot_id": "A0A8I6A123_RAT", "id": "A0A8I6A123-1", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "MRAIQSAIPNGLPACLSFLSLSFLDFLWILGQHIWNSLHWLQICGSSLESYMYQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSAS---PFNLAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSS-QGSSSNSGGSSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKS------KQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNKKESASKQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRTLMSSSQATASSCNKSGETNPVQIYIGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMSSSKEEMRELAALFYS--VVVSTVSGKELKSMVEQLIKATKDNHSPEVQHGSLLALGFTVGRYLAKKRVRMAEQ---------HDLETDDDLLPEQEEVIRSATETIGSFLDSTSPLLAIAACTALGEIGRNG---PLPIPSEGSGFTKLHLVES------LLNRIPSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSVAARDAWLVT-EEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHVEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYDLGSEQDQQELVSTLVDTLRTGKR---------VKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLRG------RPLDDVIDKLP---------------EMWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGA---AGQRTIAVLLPCLLD-KGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLS--LRATEQEKDAMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLTAWYME-KEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSS-LVPPYLGMILSALVQGLAGRTWAGKEELLKAIACVVTASSTELEKSVPNQPTTNEILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVMPLIKKNSLESMG-------VRTTKAEDENEKERELQLESLLGAFESLGKAWPRN-PDTQRCYRQEMCKLMCERLRLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCQSITYSLENKTYSSVRTEALSVIELLLKKLEEGKQWESLTAECRRLLIES-LATMETDNRPELQEKASVLKKTLESLE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYK3-1", "uniprot_id": "ECM29_HUMAN", "id": "Q5VYK3-1", "name": "Proteasome adapter and scaffold protein ECM29", "aln": "---------------------------------------MAAAAASASQDELNQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDP-----AAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPVESSKSAS---PFNLAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSA-QGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKS------KQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPK-LLSMAYSAVGKLSSRMPHLFTK--------------------DIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEG--------------------AQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGD----------------PREEVHGEAQRVLRCLPGRNRKESTSEQ-----------MPSFPEMVYYIQEKASHRMKT-PVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRTLMSSGQMAPSSSNKSGETNPVQIYIGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNNSKEEMRELAALFYS--VVVSTVSGNELKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQ---------QDLERNADTLPDQEELIQSATETIGSFLDSTSPLLAIAACTALGEIGRNG---PLPIPSEGSGFTKLHLVES------LLSRIPSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSVAARDAWQMT-EEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKR---------VKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLP-----QLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRG------RPLDDIIDKLP---------------EIWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGA---AGQRTIAALLPCLLD-KGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLS--LRATEQEKAAMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYME-KEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSS-LVPPYLGMILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSG-------VRTTKNEEENEKEKELQLEYLLGAFESLGKAWPRN-AETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLMLLEEEHADP---------------------EALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLEESKQWECLTSECRVLLIES-LATMEPDSRPELQEKAALLKKTLENLE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V677-1", "uniprot_id": "ECM29_DROME", "id": "Q9V677-1", "name": "Proteasome-associated protein ECM29 homolog", "aln": "-------------------------------------------METGPNAEIELLERVLLRLGNADSDEKLEAAVGKFLTPVILKMNSPHNVVRTKVVEVLTHIKRRLSSRGHVQIPVEALLDQYAAQ-----DSSTFLKNFAIIFITMGFPRLALEQQTALAS-KVVGCEDKLESYQDKLFALLLPVLSDMKIPDDPTQRSK---LLDLQDKPAICANFLALLQDVLLLPYGITQEQ-------------------------DVPPGLSPYSFTRIIAYN-WRAEELEKVKKGIVRFLCASVFSDLQIFVPLVVASADTRFSVATPAITELSK------LCTMLDFSNPAVTAPLYTLFAGNQSKITDR--------QTRPCCARVRQKLLQYLIKCRGKSINVTKGLQVTFDGFFGTNTNQKCKVLALQFMELLLRDGPRELVSKVSKVILTGITKIIGRDSNEPNDVQNAAYSALAQHARSFPQDVSQ--------------------DLKLVLGYFNNLASCAPELHSSIREALVSMAPAFAWKTKEKSDAMEVDKNVDSSSVKLDGQQHLLLAMLLDNAESKVQIVQNVTSVFLTSCYPEYYAPARYLLLLIAGERNSLRENVTTYLYGTSKKDHINYSMLSSIDHSKNRISSESISDFNHLSLEQRRVMLPSFQVMMSHVHEMAEKRLKKNTACVVVGRTKLPYSLEVYEELLDYLRLCLWYSAGVVAAPG----DEKYTHELREYITLHYEDT-----------EDNALHQYAQFVQRSVEAKRSESNLICLYDLLNAAPELFAAKQLHLLEPLGNTLKDVSETMRINVAQVYG--ILWAFGLSDEKFDEEVGECLNSLTQKTLEHKHGWLLVVGHTFNRKIAMLKQENKTKDFAAWPQFVNAVKIISKCLCESQWLLVSAAVKCISMIGKAVEIPNVPVEIQVPSKDGDDDDEEMTEYTSIDSSTKLVIFGV------VFQLLRSSSARQKIREDSARCLGYLAIGDGEHFTKRNLDKFLTLTKIQKDAALNIAISEAIVNTLCG------YDVNKGQ-PDEKFVNKHCNDDDFDQFLNSLIR--LVTDPNPHSRQAISVWLLAVVKHCSQRPAVLAKKELLQFAFTELLSDDSEFVQDVASRGLGLVYSISDSGSQSDLANSLLDQLIGGKR---------KVNQVTADTELFAEGMLGKTPTGGNITTYKELCSLASDLNQPDMIYQFMQLANHNATWTSKLGAAFGLKTLSAESRQKMEPYLG-----KIIPRLYRYKYDPTPKIQNSMISIWDTIVTDSKEVTERYYWEILRELLDNLTCKEWRVRIACCLAVRDLLNRPNGLKLRSEEPVRRALPDNSMEVDEVPEPELKELWFQLFRVMDDIHEGTRVAAHGTASFLGKLCVIASSSDHGK---SGTAVASSILPFLLE-TGVGHKVPEIRRVSIKTISDMIDSSGSLIAPHLATLIPCLLRATGELENTKLSYVSTRLGADNEAQEAVDTLRAEAAKSLHTMETIGKCVRYIDYSVLEKMTPEVLELMKGSVNLGTKIGCAHFVCLISIRLGKEMTPLVGKYIRACFVGIKNRNATVRKYNASAIGHLLGLAKEQSIKSLFTKLEELYAE-QPG---NRSIALTIQSINKRHHELLKDYMDSMLPLIFFAMHEEPNEE--TKANVELWKDLWHDVSPGDAG-IRLNLNVIIPKLESSLTDASWSRKAQAANAIQTIATRLSSSLDEPDRLRLIKLLLSGLQGRTFEGKERLLQALAALTKG-------LDRNHQICSSIIDAAMREARKREPVYRTMALASLGEILDQLEADRFEEVYNMSWNLLEKKELRKESDDEDEPNTSQELSADERNKRAQTLNRLKEVVWETLGKSWPRHSIETQHRYQLFFAENCTSILAESTRPVQVSLLAALTKYIERLHVFDESAQVPDLTQINQEKKIKTEETAPKTREAIVEKICTDVLAAVALAAGVPHSGLKKEALNIVLMLIKRLSGSGNGNQQPLRLIKQSFESNLEKFQRDSAPEIRCRIKDIEDKLSKLNPQN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38737-1", "uniprot_id": "ECM29_YEAST", "id": "P38737-1", "name": "Proteasome component ECM29", "aln": "-----------------------------------------MSISSDEAKEKQLVEKAELRLAIADSPQKFETNLQTFLPPLLLKLASPHASVRTAVFSALKNLISRINTLPQVQLPVRALIVQAKEPNLAAQQDSTNVRLYSLLLASKGIDRLSLQDRQQLLPLVVSNISCLTGTVAARMFHILLKLILEWVAPQESSHEQEEFVQFLQLDNDGFSFLMRQFTRFFLLVPSKQVQVSQQPLSR----------------GYTCPGLSLTDVAFFTYDAGVTFNKEQLNKFKKAIFQFVCRGMAATQTIEQSPRMIELMEFLCVVSTDSTNLSDDAAQFMKRFPMPYENEEFITFLQTLYIGNTAN------------GRPPVKAILQEKILSILNRSHFATTKAECISLICSIGLHSS--EYKLRSLTLSFIRHVAKLNYKNLNPASSSPSSTDFSTCIVSLIRNNLHAEGWPKLQLGPQTPAFNTAILQRQLQYETLGDILKRDFELVSDLSYIEFLFESLKNDLPQFRSSIQESLLSLVGHLSILPQ---------------------QSKLKLKNLLRKNLSIDEQQREDNNDAVNSIMALKFVSIKFTNAAFPFH----------------DPEARLFNIWGTVRTNRFDIIEES---------------FKGLQPFWFRVNNASINTSATVKTSDLLGSHLSETEFPPFREFLQVLIDQLDSEAASITRKS-LNNAVRFSKQCLISNAIYGKKTMVIQDEDWSVRIDKALELDDTVVSRVNEMVQGMNDDIFIRYLTLLSNEFTATNSKGEQIAIFPYQDPIFGSVLLTLLNFVSNNVLRRLEILVPDLYHLVIMKFQSLSDNDLAVCATIIGIISTAIADSTHVKRITKIAQS-----------QTMAETYVASYVVPRLYLKDQTNHIESDSILNLLNILTTHLSHPGTNKDMILKLVCQVTKFGLLLQVSAQERKDFLKKVMDTIQDKLINDVTAIQTWSYLSLYSTDLENSSLFQEKLLETNVSKQNDFLFSVGESLSVVAGKWSSKYLIKQIDIPNFNVEIMQQKFPATNVTTILDEIFSG--CDSTKPSLRKASCIWLLSYIQYLGHLPEVSSKCNDIHLRFMRFLADRDEFIQDSAARGLSLVYEIGGSDLKESMVKGLLKSFTESTAGSASTSATGISGSVSEETELFEPGVLNTG--DGSISTYKDILNLASEVGDPALVYKFMSLAKSSALWSSRKGIAFGLGAIMSKSSLEELLLKDQQTAKKLIPKLYRYRFDPFQAVSRSMTDIWNTLIPESSLTISLYFNDILDELLCGMANKEWRVREASTSALLQLIQS------QPQEKFSEKML---------------KIWTMAFRTMDDIKDSVREVGTKFTTVLAKILARSIDVEKGVNPTKSKEILDNILPFLWGPHGLNSDAEEVRNFALTTLIDLVKHSPGAIKPFTPKLIYDFITLFSSIEPQVINYLALNAANYNIDANVIDTQRKNGVTNSPLFQTIEKLINNSDDCMMEEIINVVIKASRKSVGLPSKVASSLVIIILVKRYSIEMKPYSGKLLKVCLTMFEDRNESVNIAFAISMGYLFKVSALDKCIKYSEKLITKYFEPTSTENNKKVVGTAIDSILNYAKSEFDNVASVFMPLIFIACNDE------DKDLETLYNKIWTEASSSGAGTVKLYLPEILNVLCVNIKSNDFSIRKTCAKSVIQLCGGINDSIPYPQIVKLFDISREALSGRSWDGKEHIVAALVSLTEKFS---QTVADNNDLQESINHVMYTEVSRKSMKYVKKILPLYARYINVNPQE--ETITFLIEKAKEMIRLLGSE--------SDDSEGSIKQTSDESTIKRIKPNTEITQKSSKEN--IENEEYVINLLKVSVDICNNSKSRYPMNLLEFIIDEIAYLFHNDRIIHTWR-------------------TQLAASEIGISIVGRFSTISSADFIQNVGRLWDQTFPINCNKETIENVKLQMIKFGGLIIQK-IPSLQNNIEENLRLLNSIDSTSRIELELKNIGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:. ***. *:: :::: : .**.*::**: *.: **. *.. * :: *:.: ::*:**.:*: * : : :::: . * **.::.: * . : . . :: :*: : . * :.:: . : :: : : .**:* . . .:: : . : *:*:: * .*.:*: . : . .*.:. :*.. : :.* . : .:: *: . * : :: *:: * :.: : . : *:..: : * : *:*.*:. : . . ..::. * .: . . :. : : . : *: : *: * . *: : :*:*:* :. : * * : . :: .: . . . :: . . : . : .** : .: : ::: : : . . : * . : *:: * * .*. :. .: .. :.:. .:.: . : * *:: : . : . . :: : :: : :. :. : : : . . : . : . : : . . : . * . : . : : . : : .*:.: . . : : * : *: : :::.*:: . . : :. : .:: ..:* *:* .:***: :: . * :: : :: * .*:: .*: ** *::**.***.:... :..:.. *:. : .. .*: :* :* * *.. . .::***:: .***::.:* ::*:**.**: * *.*: * ***: .: :.: : :::*:****::** : .:* .**::::.: . . * :** :*: .:: : **** :. *: :*:. :. : . : ::* **. ***::..* .. . *.*: . . :* . :** * *: . *:* .::.*: .: . : . : *. ..** :: . :* :.*:: : .:*: * ..... ::** :. * .:: :: : : : .*.* :* ..: .: : : ::.* ** : . : : :** :. * ::*:*. : .. . ** * * : . :*.:* . . :.: . .:** *:. :: * ::..:* : ... * ::* * :: : . .:. : * :: :. .. : * :: ..* **:: ***.:: *:..:. *: ..* .. * :.. * :. . :. : : . : : * . .:. : . * *: .: :. * : : . *. :.:* : : * :. : .. : . . . . . : . . : : . ::. : .:: : ::: . . .*: ", "identical_positions": 207, "similar_positions": 593, "identity": "10.0%" }, { "cls_id": "homologset.agr.SGD:S000001023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62931-1", "uniprot_id": "GOSR1_RAT", "id": "Q62931-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88630-1", "uniprot_id": "GOSR1_MOUSE", "id": "O88630-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95249-1", "uniprot_id": "GOSR1_HUMAN", "id": "O95249-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VE50-1", "uniprot_id": "GOSR1_DROME", "id": "Q9VE50-1", "name": "Golgi SNAP receptor complex member 1", "aln": "-MGGSS--YDVLRKQARSLENEIDLKLVAFSKIGAGSGGGGS--GGLG--GVDTSPLLG----EHVFDSLSEEIEQMLEKLSSLNESMSDLPASG------AAAMHTLQRHREILQGYRQEFNKICANHTMRIEREELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38736-1", "uniprot_id": "GOSR1_YEAST", "id": "P38736-1", "name": "Golgi SNAP receptor complex member 1", "aln": "--MSSQPSFVTIRGKAISLETQTESLLSKYSTFAQTTSSEQT----------------------GQEKKIDKQLEGILGQRQDVIDSLTQICDSN--PAISASKLSQLHRHKEILQDHWKSFRNIRSSIQQERNRLNLLFSVKNDIANSTTDAPAPIGDADEYIQNETRRIDQSNNVVDRLISQAWETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTLCILFLFFTW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. : :* :* .**.: : * :*.: . : ..: ::* :* : .: :.::: * *: : *:**::***.: :.*.: :. :* :*: . .. . .. * :* :: .:..::: *. * *:.:: :* :: :.:. :*:* :..** :** ::::::::*. : :* ::*:: ", "identical_positions": 34, "similar_positions": 94, "identity": "13.55%" }, { "cls_id": "homologset.agr.SGD:S000001024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63060-1", "uniprot_id": "GLPK_RAT", "id": "Q63060-1", "name": "Glycerol kinase", "aln": "-----------------------MAAAKKAVLGP-------------LVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQ-----------------------------------------------------------------EFPREGWVEQDPKEILQSVYECIEKTCEKLGQLN-------IDISNIKAIGVSNQRETTVVWDKLTGEPLYN-AVVWLDLRTQSTVEKLSKRIPG---NNNFVKSKTGLP-LSTYFSAVKLRWLLDNVKKVQEAVEENRALFGTIDSWLIWSLTGGINGGVHCTDVTNASRTMLFNIHSLEWDKELCEFFGIPMEIL--PNVRSSSEIYGLMKISHSLKAGALEG------------VPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSEHGLLTTVAYKL------GRDKP----VYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTSNKILMQLQADILY--IPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPED--LSAVTMERFEPQIN-AEESEIRYSTWKKAVMKSIGWVTTQ--SPESG--DPSIFCSLPLGFFIVSSMVMLIGARYISGIP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64516-3", "uniprot_id": "GLPK_MOUSE", "id": "Q64516-3", "name": "Glycerol kinase", "aln": "-----------------------MAAAKKAVLGP-------------LVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQ-----------------------------------------------------------------EFPREGWVEQDPKEILQSVYECIEKTCEKLGQLN-------IDISNIKAIGVSNQRETTVVWDKVTGEPLYN-AVVWLDLRTQSTVENLSKRIPG---NNNFVKSKTGLP-LSTYFSAVKLRWLLDNVKKVQEAVEENRALFGTIDSWLIWSLTGGIHGGVHCTDVTNASRTMLFNIHSLEWDKELCEFFGIPMEIL--PNVRSSSEIYGLMKISHSLKAGALEG------------VPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSEHGLLTTVAYKL------GRDKP----VYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTSNKILMQLQADILY--IPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPED--LSAVTMERFEPQIN-AEESEIRYSTWKKAVMKSIGWVTTQ--SPESG--DPSIFCSLPLGFFIVSSMVMLIGARYISGIP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32189-3", "uniprot_id": "GLPK_HUMAN", "id": "P32189-3", "name": "Glycerol kinase", "aln": "-----------------------MAASKKAVLGP-------------LVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQ-----------------------------------------------------------------EFPREGWVEQDPKEILHSVYECIEKTCEKLGQLN-------IDISNIKAIGVSNQRETTVVWDKITGEPLYN-AVVWLDLRTQSTVESLSKRIPG---NNNFVKSKTGLP-LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEIL--PNVRSSSEIYGLMKISHSVKAGALEG------------VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKL------GRDKP----VYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTSNKILMQLQADILY--IPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPED--LSAVTMERFEPQIN-AEESEIRYSTWKKAVMKSMGWVTTQ--SPESG--DPSIFCSLPLGFFIVSSMVMLIGARYISGIP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14409-1", "uniprot_id": "GLPK3_HUMAN", "id": "Q14409-1", "name": "Glycerol kinase 3", "aln": "-----------------------MAASKKAVLGP-------------LVGAVDQGTSSTRFLVFNSRTAELLSHHQVEIKQ-----------------------------------------------------------------EFPREGWVEQDPKEILHSVYECIEKTCEKLGQLN-------IGISNIKAIGVSNQRETTVVWDKITGEPLYN-AVVWLDLRTQSTVESLSKRIPG---NNNFVKSKTGLP-LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEIL--PHVRSSSEIYGLM------KAGALEG------------VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKL------GRDKP----VYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTSNKILMQLQADILY--IPVVKPLMPETTALGAAMAAGAAEGVDVWSLEPED--LSAVTMERFEPQIN-AEESEIRYSTWKKAVMKSMGWVTTQ--SPEGG--DPSVFCSLPLGFFIVSSMAMLIGARYISGIP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU65-1", "uniprot_id": "GLPK2_MOUSE", "id": "Q9WU65-1", "name": "Glycerol kinase 2", "aln": "-----------------------MAASKQTSAGP-------------LVGAVVQGTNSTRFLVFNSKTAELVCSHQVELTQ-----------------------------------------------------------------EYPKEGWVEQDPKEILKSVYECIAKACEKLAEVN-------IDISNIKAIGVSNQRETTVVWDKFTGDPLYN-AVVWLDLRTQSTVETLTKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNLRPIQKAVEEGRAMFGTIDSWLIWCMTGGVNGGIHCTDVTNACRTMLFNIHSLEWDKDLCDFFEIPMSIL--PNVCSSSEIYGLMT------SGALEG------------VPISGCLGDQSAALVGQMCFHEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTLAYKL------GKNKP----VFYALEGSVAIAGAVIRWLRDNFEIITTSGEVENLAREVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTNNRILMQLQADILH--IPVVKSVMPETTALGAAMAAGAAEGVNVWSLEPED--LSTILMERYEPQIQ-ATESEIRFSTWKRAVMKSMGWVTAK--DPENG--DNPVFSCLPLGFFIVSSMTLLIGARCVSTAEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FNM6-1", "uniprot_id": "F7FNM6_RAT", "id": "F7FNM6-1", "name": "glycerol kinase", "aln": "-----------------------MADSKETPEEP-------------LVGAVVQGTNSTRFLVFNPKTAELVGSHQVELTQ-----------------------------------------------------------------EYPKEGWVEEDPKEILQSVYECIAKTCEKLTEAN-------IDTSKIKAIGVSNQRETTVVWDKFTGEPLYN-AVVWLDLRTQSTVESLNKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNLRPIQKAVEEDRALFGTIDSWLIWCMTGGVNGGIHCTDVTNASRTMLFNIHSLEWDKELCKFFEIPMSIL--PNVRSSSEIYGQMT------SGALEG------------VPISGCLGDQSAALVGQMCFQEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTVAYKL------GKNKP----AFYALEGSVAIAGAVIRWLRDNFELITSSGEVEDLAREVGTAYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREIVDAMNRDCG--------------------IPLSHLRVDGRMTNNKILMQLQADILH--IPVVKSVMPETTALGAAMAAGAAEGIDVWSIEPED--LSSMLMERYEPQIQ-ATESEIRFSTWKRAVMKSMGWVTAK--DPESN--ANPVFACLPLGFFIVFLRHLPP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14410-1", "uniprot_id": "GLPK2_HUMAN", "id": "Q14410-1", "name": "Glycerol kinase 2", "aln": "-----------------------MAAPKTAAVGP-------------LVGAVVQGTNSTRFLVFNSKTAELLSHHKVELTQ-----------------------------------------------------------------EFPKEGWVEQDPKEILQSVYECIARTCEKLDELN-------IDISNIKAVGVSNQRETTVIWDKLTGEPLYN-AVVWLDLRTQTTVEDLSKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLL--PNVFSSSEIYGLIK------TGALEG------------VPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKL------GREKP----AYYALEGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDCG--------------------IPLRHLQVDGGMTNNKVLMQLQADILH--IPVIKPFMPETTALGAAMAAGAAEGVSVWSLEPQA--LSVLRMERFEPQIQ-ATESEIRYATWKKAVMKSMGWVTSQ--SPEGG--DPSIFSSLPLGFFIVSSMVMLIGARYISGVP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8F7-1", "uniprot_id": "D3Z8F7_RAT", "id": "D3Z8F7-1", "name": "glycerol kinase", "aln": "-----------------------MADAPKAVLGP-------------LVGAVDQGTSSTRFLVFNPQTAELLCHHQVEIAQ-----------------------------------------------------------------EFPREGWVEQDPKVILQSVYECIEKTCEKLGQQS-------IDISNIKAIGVTNQRETTIVWDKFTGEPLYN-AVVWLDLRTQSTVENLNKSISA---SNNFIKIKTGLP-ISTYFSAVKLHWLIENVKNVQKAIEDGRAFFGTVDSWLIWCMTGGINGGVHCTDVSNASRTMLFNIHSLQWDEELCEFFGIPMTIL--PRIRSSSEIYGLMK------SGVLEG------------VPISGCLGDQSAALVGQLCLQDGQAKSTYGTGCFLLCNTGQKCVNSDHGLLTTVAYKM------GREEP----VYYALEGSVAIAGAVVSWLKNNLQIIKSSSDIEKLAEKAGTSYGCYFVPAFSGLYAPYWDPSARGIICGLTQFTNKFHIAFAALEAVCFQTREILDAMNSDCG--------------------IPLTHLQVDGGMTANKILMQLQADILC--IPVMKPFMPETTALGAAMAAGAAEGIRVWSLDPKD--LTGVQMEKFEPQIN-VEESEGRYSTWKRAVMKSMGWVLTQ--SPDGH--DPSIFRSLTLGFYIGIWQP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58J5W5-1", "uniprot_id": "A0AC58J5W5_DANRE", "id": "A0AC58J5W5-1", "name": "glycerol kinase", "aln": "----------------MNDTMPMAASSNRIMLGP-------------LVAAIDQGTSSTRFLVFNAKTAELLSHHQVEIKQ-----------------------------------------------------------------SFPKEGWVEEDPKEILQSVYECMDRTCEKLTQLN-------IDVSNIKAVGVTNQRETTLVWDKQTGEPLYN-AIVWLDLRTQSTVERLINKTPGK--NKNHLKDKTGLP-ISTYFSAVKLRWLMDNVEKVHEAVLSHRAMFGTVDSWLIWCLTGGKNGGVHCTDVTNASRTMLFNIHTMDWDPELCIYFDIPMGIL--PKVRSSSEIYGLMKISSKLKSGPLTG------------VPISGCLGDQSAALVGQMCFKDGQAKNTYGTGCFLLKNVGTKPVMSDHGLLTTVAYKL------GRDKP----ACYALEGSVAIAGAVVRWLKDNLGIIQTSTELEKLAADVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNRSHLAFAALEAVCFQTREILDAMNQDSG--------------------INLSQLQVDGGMTSNRLLMQLQADILC--IPVVKPSMPETTALGAAMAAGAAEGVSVWSLNPED--LTEVTSEKFEPQINPEAESELRYARWKKAVQRAMNWETIE--PVNSGNEDTSIFSSVPLGFYILGSMFMLIGAKYIAGQKLA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W095-1", "uniprot_id": "Q9W095_DROME", "id": "Q9W095-1", "name": "glycerol kinase", "aln": "----------------MTEGKNLPHSSADVPFRSKELRKQSLIQHTGLVGVIDEGTKTIGFSIYTTPDFKEIAAHRVELSV-----------------------------------------------------------------ITPQDGWYEQDPLEMMASINKCAEEAIKQLPEQG-------FSASDIVTVGITNQRETTIVWDAVTGKPLYN-ALLWKDIRTSTTVEQIVAKVQD----PNHFRSSTGLP-ISTYFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLT---NGALHITDVTNASRTLLMNLETQAWDPVLLKTFGIREEML--PTIHSCSEIFGKITS----ERSPLRG------------MTLSGIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHGLLTTVAYKL------GPQAP----TIYAIEGAVSVAGHALSWLQNKVRILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQFTRKNHIVRAALESICFQTRDILECMHQECG--------------------YEINKLHADGKLTTNNLLMQLQADTIG--MPVFRSQLMDSTAFGAAMCAAQADGVNLCQFEPEKRYYENVHYDTFLATTT-DVERKERYGKWKRAVERSLGWVIKQKKTREYTEENYRMLSSLPASIFLISSFAMLVHSLAASGQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0U0-1", "uniprot_id": "Q9W0U0_DROME", "id": "Q9W0U0-1", "name": "glycerol kinase", "aln": "----------------MDSPTTETTPPPPTLSGP-------------FVGAIDEGTTSARFIIFRAGTDEIVCFHQIEVES-----------------------------------------------------------------IFQKEGWCEQDPMAIVNTVNECITGACKKLVAVG-------GKVEEIITIGITNQRESTVVWDRNSGQPLVN-AIIWLDNRTTSTVEELLETIPNNARNINYLRPLCGLP-LSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGTIDTWLMYNLTGGKDCGVHKTDVTNASRTMLMNIETLQWDANLLKFFGLPKTIL--PEICSSSEFYGSIA------QGVLQG------------IGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTHGLLTTVGYQL------GRKAV----PFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSEETTSEHIVRATLEAVCFQVRDILDSMHKDCK--------------------IPLAKLMVDGGMTVNNLFLQLQSDLVG--IQVLRAKIAETTALGAAMAAYKAVENRYQMEAPLS---KSGPREAIKPSIS-ATDRNLRYQKWKMAIDRSLNWETST----------------LPQGEREAFDGA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32190-1", "uniprot_id": "GLPK_YEAST", "id": "P32190-1", "name": "Glycerol kinase", "aln": "MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSRCILFN-RWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAEGYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINSERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSVD--RQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT---KQKAFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIMEKLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKD--LHDVKKWVFYNGME-KNEQISPEAHPNLKIFRSESDDAER--RKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : **.: :: : : *::* : ** * .* :: .: :* : .* . .: :*::* **:*::*. :*.*: * .::* * ** . *. .: *** :*.*** *::*: :* :* . **:*:*::: :* . . :**:**.** ::*: : :* * : : :: * : *.*: :* : . : : . :*:* *:::** . * :* ** :***** *.* . : * ** ***:.: : * . :*:**:*::** .. **:::. :: * : * . : . *****.**:**** .**. : *::: * *:. *::*.:***.* *:..* :. : * .** :: .. .:*:*:* : : * :. : **:***:.* * : : : :: . ", "identical_positions": 124, "similar_positions": 155, "identity": "17.06%" }, { "cls_id": "homologset.agr.SGD:S000001025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62425-1", "uniprot_id": "RL7A_RAT", "id": "P62425-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62424-1", "uniprot_id": "RL7A_HUMAN", "id": "P62424-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12970-1", "uniprot_id": "RL7A_MOUSE", "id": "P12970-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46223-1", "uniprot_id": "RL7A_DROME", "id": "P46223-1", "name": "Large ribosomal subunit protein eL8", "aln": "MVVKKPRPKKKPVTKKVAPAPLAVKKPVVKKVVNQLFEKRPKNFGIGQNVQPKRDLSRFVRWPKYIRVQRQKAVLQKRLKVPPPIHQFSQTLDKTTAVKLFKLLEKYRPESPLAKKLRLKKIAEAKAKGKDVE-PKKKPSYVSAGTNTVTKLIEQKKAQLVVIAHDVDPLELVLFLPALCRKMGVPYCIVKGKARLGRLVRRKTCTTLALTTVDNNDKANFGKVLEAVKTNFNERHEEIRRHWGGGILGSKSLARISKLERAKARELAQKQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17076-1", "uniprot_id": "RL8A_YEAST", "id": "P17076-1", "name": "Large ribosomal subunit protein eL8A", "aln": "----------MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDK--RAKNSDSA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ******* .*. :*. * * .. ******** :****:*:*:*:**.*:*:***: :* ******.* ** :**: **.: :** .*****: ** ** * * **. .. :* : * * *. *:*:***:**:**:****:***:******:******.*:******* **.:**.:. *:* * :*:. :.*::.:: :*: ::::*:::****.:** *: *:: * :** : * ", "identical_positions": 125, "similar_positions": 73, "identity": "45.96%" }, { "cls_id": "homologset.agr.SGD:S000001026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1P4F7-1", "uniprot_id": "A0A8M1P4F7_DANRE", "id": "A0A8M1P4F7-1", "name": "", "aln": "MESRDSKEPEQLRKLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDAAMTARPHKVDGRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIETIDIMEERSTGKKRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQEMQSSSNQRYRGGGGGNFTGRGGNFGRGGYGGGRGGGDGYNGFGGNYGGGPGGYGGGRGGYGGGPGYGNQGGGGGFGGFDNYNDRGNFGGNFGGGGGSSGGGGGGNYNDFG-NYGGQQSNFGPMKGNNFGGR----NSGPYGGGGYGSGGGGGGGGYGSRRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10080-1", "uniprot_id": "SSBP1_YEAST", "id": "P10080-1", "name": "Single-stranded nucleic acid-binding protein", "aln": "MSAEIEEATNAVNNLSINDSEQQPRAPTHKTVIDPEDTIFIGNVAHECTEDDLKQLFVEEFG--DEVSVEIPIKEH-TDGHIPASKHALVKFPT----------KIDFDNIKENYDTKVVKD--------REIHIKRARTPG-------------------------QMQRGGFRGRGGFRG---RGGFRGGFRGGYRGGFRGRGNFRGRGGARGGFNGQKREKIPLDQMERSKDTLYINNVPFKATKEEVAEFFGTDADSIS-LPMRKMRDQHTGRIFTSDSANRGMAFVTFSGENVDIEAKAEEFKGKVFGDRELTVDVAVIRPENDEEEIEQETGSEEKQE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:. .: .: :.:* *.. . :. : :: :: ..: * :: ::. : : . :. .**.. :. : * .**:: .*:*: : : ** ...***: : ::: . *.* . *:.* :: . . * .: :.. . :*** *.* ***. **** ** .* . : .: . . .. : . : * . ..:. * . : * *.... * : *. : . ::: :**: **.* : . . . *. .:. ", "identical_positions": 48, "similar_positions": 114, "identity": "13.91%" }, { "cls_id": "homologset.agr.SGD:S000001027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4P9-1", "uniprot_id": "MRP7_MOUSE", "id": "Q8R4P9-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "---------------------------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPR--------TTNHSPALNPGWRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGRSRGPLALALAAFLPTPALVLT-LLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQE-------PWTHDPFLSS--ESQETEVAEDGESWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQ-----------------------------------------LWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLE------------------EGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALK-------LGP-----SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMGHQ----LTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDP---------------IGASQKTFISH------------------------------LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSEL-----------------------SKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEK----GVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTR--LLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPL----VQAVPTAWAEKEQVATSG-----------------------QSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSLLLMQATRNGAD-WWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQ-SPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLS---------------EVAVAM-GGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX04-1", "uniprot_id": "D3ZX04_RAT", "id": "D3ZX04-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "---------------------------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAVLSACHLGTPR--------TNNIIQPFNPGWRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGHSRGPLALALAAFLPTPALVLT-LLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPRE-------PWTHDPFLSP--ESQEREVAEDGESWLSRFSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQ-----------------------------------------LWRALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLE------------------EGQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLK-------LGP-----SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACVYLWAALPVVICIVIFITYVLLGHQ----LTATKVFTALALVHMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDP---------------TGTSQKTFISH------------------------------LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDL-----------------------SKGFGLATQEPWIQCATIRDNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEK----GVTLSGGQRARIALARAVYQEKTLYLLDDPLAAVDADVANHLLHRCILGVLGHTTR--LLCTHRTEYLERADLVLLMEAGRLVRAGPPSEILPL----VQAAPTALADKEQVTDSG-----------------------QSPSVHNLEKTT-EELDVAQNTSGRLVQEESKSEGAVALHVYRAYWRAMGSGLATAILISLLLMQATRNGAD-WWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGN----LLSIPLHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDIPQEPHGQPPQ-SPHQR-VSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLS---------------EVAMAI-GGLDGELGERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T3U5-1", "uniprot_id": "MRP7_HUMAN", "id": "Q5T3U5-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "---------------------------MERLLAQLCGSSAAWPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACYLGTPR--------SPDYILPCSPGWRLRLAASFLLSVFPLLDLLPVALPPGAGPGPIGLEVLAGCVAAVAWISHSLALWVLAHSPHGHSRGPLALALVALLPAPALVLT-VLWHCQRGTLLPPLLPGPMARLCLLILQLAALLAYALGWAAPGGPRE-------PWAQEPLLP---EDQEPEVAEDGESWLSRFSYAWLAPLLARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGAR-----------------------------------------LWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLE------------------EGQEPLSHGLLYALGLAGGAVLGAVLQNQYGYEVYKVTLQARGAVLNILYCKALQ-------LGP-----SRPPTGEALNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFCGWEQALGARVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQ----LTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQLFLDLPNHNPQAYYSPDPPAEPSTVLELHGALFSWDP---------------VGTSLETFISH------------------------------LEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGL-----------------------SKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEK----GVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILGMLSYTTR--LLCTHRTEYLERADAVLLMEAGRLIRAGPPSEILPL----VQAVPKAWAENGQESDSA-----------------------TAQSVQNPEKTK-EGLEEEQSTSGRLLQEESKKEGAVALHVYQAYWKAVGQGLALAILFSLLLMQATRNAAD-WWLSHWISQLKAE-NSSQEAQPSTSPASMGLFSPQLLLFSPGNLY--IPVFPLPKAAPNGSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNATPTGRILNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLPPLSIMYYHVQRHYRASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQP-----LQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLS---------------EVITSM-GGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLV8-1", "uniprot_id": "A0A8M9QLV8_DANRE", "id": "A0A8M9QLV8-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "---------------------MGGDIGAAEFISELCHTDVDSPFPVWQNGTISPCANQLLLGSLPHAVFAVISACYISVPR--------LIHIVSSLPIGWSLRAASTLLVFLLFIGDLVLVFELQAP---DIYLDTLADGCGILAFLVHFGAILSLQKSIYRRTRGPALLPVALILSIPNLAFN-LTAYTQEIIHHGVSQPLQVIRLAFTVTRGALVLVYLLGYIFPCYRTQRDLLSCNAEDEAPLIVTFEPFEEVTVAEDGSSLLSRLLYLWLNPLLNRGKRGELERPSDVFELPSRLRTKSVTRRFYQCWEKCLQSRALKRPERPDRRPRGNLQDNSWSEAQPERICEGEAEHEVKLLQVLHKAFGLRYYLLGGLKLVASMLAFAGPLLLGGLVGFME------------------TEGAPLSKGVWCTVGLFASTFLAALLKNIFVYEVSKVALEARAAVISTIYSKALK-------VNAP--SLARFNMGEVVNFMSTDTDRVVNFFNSFHEVWSLPFQFVLALYLLYLQVGVAFLGGVGVAVLLVPLNKVLASRILENNKHMLQHKDGRVKLMTEILFGIRVLKYYNWEEHFTQKIEEARKKELHHLKLLKYLDAVCVYTWAALPVVISILTFITYVLLGNN----LTAAKVFSTLALVGMLILPLNAFPWVLNGTLEAKVSLDRIQRFLAVQDQDLSVYYSQVCPEDPPSAVQMVQASFSWKQSEEADSVSIPDDITEEGSPPHSFYLHA---------------------------LNLNVKRGSLVVVVGKVGCGKSSLLAAITGELTRCGGEVFVQGR-----------------------EQGFGLAVQEPWIQHATVQDNILFGRDYDNMFYQSVIQACALADDLNILPGGDQTEVGEN----GVTLSGGQKSRLALARAVYMDKEIYLLDDPLAAVDADVAHHLMEKCILGILKDKTR--ILCTHRIEFVDKADVVVLMDNGMIVKTGTPSAVLSL----VKGP-------KDSKNSS-----------------------NAKEKDSAGSEEMEASEPELKAELEMFGEEQKQMGTLSWAVYRSYWKAVGGCMAVAVLLALFLMQASKNVSD-WWLSHWISHMKDN-MTELVSVSATPLLMLSFLSPGRLVFNASARG--------SESSGNMSSELKFYMTVYGSLAAANTVFTAARAFLFAYGAICAATVIHKRLLSSVLKATMTFFDTTPLGRILNRFSSDIYSVDDSLPFVLNILLANVFGLLGMLIVMSYGLPWVLLPLVPLGALYYQTQCFYRYSSRELKRLCSLTLSPVYSHFSETLSGLSTVRASGHTTRFEEENERRLEQNQRCLFNSNAAMQWLDIRLQMIAVTVVTGISVIAVIQHQLKSIDPGLVGLSLSYALSITNLLSGLIFSYAQTEMQLVSIERTEEYSTSIPQEPQQAS-----LEVSDRWPERARVEFVDVVLSYRPGLPNALDGVSVEVLPGEKIGIVGRTGSGKSSLFLALFRMVELNQGQILLDGVDISSVRLSDLRSKLAIIPQDPFLFSSSVRENLDPHGRHPDYRLLEALEQCHLG---------------NVVQRN-GGLDSEVGERGKSLSVGQRQLLCLARALLTEANILCIDEATASVDQKTDMLLQKTIREKFKDKTVLTIAHRLNTIMDSDKVLVMHAGKVVEFDSPATLCQREDSAFQKLLRGGEDQV--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09428-1", "uniprot_id": "ABCC8_HUMAN", "id": "Q09428-1", "name": "ATP-binding cassette sub-family C member 8", "aln": "------------------------------MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVK----PPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGAR---------------------------------------AIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMH-------LSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFS--PSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQ--CAPHEPTPQGPASKYQAVPLR--VVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGER----GINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRS----ECQLFEHWKTLMNRQDQE--LEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAID-YWLAKWTDSALTLTP--AARNCSLS--------------------------------QECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLA---PSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLK---------------LVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TDX1-1", "uniprot_id": "A0AB32TDX1_DANRE", "id": "A0AB32TDX1-1", "name": "", "aln": "--------------MIYKMMRAYRPTPVSNSTLSFCGSDN-SSAYKVDNGLLNNGCFLDALDVVPHVFLLFSTFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWLLTAILLFLLVCEIAEGIVSDGFNQSRHLHLYMPAGLAILAAITSIIYYHNIETSNFPKLLIALLIYWTLAFVTKTIKFVKYDDHGIGLRQLRFCITGLLALLYGLMLGVEVNVILRRRYMWFACPTEVK----PPDDLQDLGVRFLQPFVNLLSKSTYWWMNTFITSAHQRPIDLKTIGKLPKSMRALSNFQQLRKAFDSQMESGCVHLQGSG---------------------------------------WMWRALRQAFGAPLLLSICFRFISDLLGFAGPLCISGILQHISRDNHTAPPPVKLLGVHFISSEVFFANAYVLAVLLFLALLLQRTFLQASYYVAIENGINLRGAVQTKIYNKIMR-------LCTSNMSMGDMTTAQICNLVARDTNQLMWFFFLCPNLWAMPVQIVIGVLLLYYLLGASALIGATVITVLAPLQYFVATRLSRAQKSTLEYTSERLKKTNELLRGIKLLKLYAWEHIFRSSVEETRRQELTSLRTFALYTSLSIFMNAAIPIAAVLTIFVVHVHLQSSSDFALSPAVAFGSLSLFHILVTPLFLLSSVLHSTVKALVSVQKLSEFLSSAEIETDQDPIAQTPANNNGNIKSVYALQLQAKLVNRKNKAKQDVNRNFEQQDQELRASAQHEDNICIKIVNGYFSWT-QGCPTLTNIDIKVPFGQLTMIVGQVGSGKSSLLLAALGEMQKISGSITWNSLPRSDSDENIR-AHDMSGRQSFTRRGSVAYASQRPWLLNATVEENILFDTAPNVKRYKDVIEVCQLGPDIDTLPQGDQTVIGERVRHLGIILSGGQRQRISVARALYQQTNVVFLDDPFSALDIHLSDHLMHEGILKFLRQEKRSVVLVTHKLQYLPHADWIIAMRDGTVQTQGTLKDIQCA----EPELFEQWRTLMNRQDKENSTELKRKSFRRAMMYSRDTVATDDEDEAVADVAVSEVKDSSTSTDEDSLGAELRHRTTIPWSSFATYLKAAGLFLLPLLIVSQLAKHSLMVAID-FWLAHWTSDVIAAQSESAERNCTFT--------------------------------KDCVFSHSWYLQVFCLLCALGIVLCLVTSLAVEWTGLRVAKELHCSLLRIIVLAPMRLFETTPLGNILNRFSTDTNTIDQHIPVTMECLSRSTLLCVSAVGVISYVTPVFLIALLPLTVACYFIQKYFRVASRDLQQLEDSTEMPLLSHYSQTIEGLTTIRAFRHEQRFKKKLLEHTDANNISSLFLTAANRWLEVRMEYIGALVVLIAAVASITNALYRQLSAGLVGLGLTYALMVSNYLNWIVRNLADMEVQLGCVKRVSGLIHTQPESYDNIMT---PAQVPAGWPKYGEIQIQNLSVRYDSSLKPVLKHVSAHIRPGQKVGICGRTGSGKSSFSLALFRMVDTFEGQISIDGIDISKLPLQTLRSKFSIILQDPILFSGTIRFNLDPERKATDEMLWEALEIAQLM---------------PVVKALPGGLDAVVTEGGENFSQGQRQLFCLARAFVRKSSILIMDEATASIDMATESILQKVVMTAFADRTVVTIAHRVHTILGSDVVIVMKHGGIIEYDEPDVLLEQKDSVFSAFVRADK-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O60706-1", "uniprot_id": "ABCC9_HUMAN", "id": "O60706-1", "name": "ATP-binding cassette sub-family C member 9", "aln": "------------------------------MSLSFCGNNI--SSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVK----PPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTP---------------------------------------SIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGIS--ETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILR-------LSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGN---NLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDS-WRTGESSLPFESCKKHTGVQPK--TINRKQPGRYHLD---SYEQSTRRLRPAETEDIAIKVTNGYFSWG-SGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESE----PSFEATRS-----RNRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGER----GINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTK----DVELYEHWKTLMNRQDQE--LEKDMEADQTTLER-KTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAID-YWLATWTS------------EYSIN--------------------------------NTGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSN----SGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMD---PSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLK---------------NMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38735-1", "uniprot_id": "VMR1_YEAST", "id": "P38735-1", "name": "ABC transporter ATP-binding protein/permease VMR1", "aln": "MGTDPLIIRNNGSFWEVDDFTRLGRTQLLSYYLPLAIIASIGIFALCRSG-LSRYVRSAECDLVNEYLFGAQEERKEDNSIERLLRNSNTQANYVNVKKQGRILKLRHFDITTIDVKQIDAKNHGGLTFSRPSTSDHLRKSSEIVLMSLQIIGLSFLRVTKINIELTNRDVTTLLLFWLILLSLSILRVYKRSTNLWAICFTAHTTIWISTWIPIRSVYIGNIDDVPSQIFYIFEFVITSTLQPIKLTSPIKDNSSIIYVRDDHTSPSREHISSILSCITWSWITNFIWEAQKNTIKLKDIWGLSMEDYSIFILKGFTRRNKHIN---------------------------------NLTLALFESFKTYLLIGMLWVLVNSIVNLLPTILMKRFLEIVDNPN---------------RSSSCMNLAWLYIIGMFICRLTLAICNSQGQFVSDKICLRIRAILIGEIYAKGLRRRLFTSPKTSSDSDSISANLGTIINLISIDSFKVSELANYLYVTVQAVIMIIVVVGLLFNFLGVSAFAGISIILVMFPLNFLLANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLKKSLVWSVTSFLWFVTPTLVTGVTFAICTFVQHED---LNAPLAFTTLSLFTLLKTPLDQLSNMLSFINQSKVSLKRISDFLRMDDTEKYNQLTISPDKN---KIEFKNATLTWNE---------------NDSDMNAFKLCG---------------------------LNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPDCEG----------LTNSFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDLTEIGEK----GITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPLMKNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITELQSKGLFKEKYVQLSSRDSINEKNAN-----------------RLKAPRKNDSQKIEPVTENINFDANFVNDGQLIEEEEKSNGAISPDVYKWYLKFFGGFKALTALFALYITAQILFISQSWWIRHWVNDTNVRINAPGFAMDTLPLKG-------------------------MTDSSKNKHNAFYYLTVYFLIGIIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAVIVFVLYFFVGKWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNNRAFFYLSVTVKWFSFRVDMIGAFIVLASGSFILLNIAN--IDSGLAGISLTYAILFTDGALWLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKDGEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYDEKKIFKALSQVNLISSHEFEEVLNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSIDYDSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIFYSMCRDSGGLELLKQIAKQSSKMMK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : . .: : : . : :: : : : : : : : : . . : . . : :: . : .: :* : :: : .: : :: : : . : : . . : : :. * : :* * :: . . *::. :: :: : . : : : **: :* : . * : :: *:: .:*. : :: * . *:. .* * .*:::* **. : :: * :*: * : : . * * . . .. .* :*:*. :* ** :. :: :: :*:.::. ** . . . :.. * * ::*..*.***:** . **: * : .. . * .*: *:.:*: * : *. * :.* * *:. ** ** * :**. *: *****: *:.:***:* :*** ::*:* . : : . * * :: : : .*. : : * : *. . . : : . : :. * * :.: : :*: * . : . * : : . :. : .: :. ** :: . : ::: ** * ::**** * *: : :: . : :: * .* : : : : ::*:.* . * *: * ::* *: .:** ** . . : *: . : .: :*:..* : :.. :* . : .**.*: * **: .:. :: : * : .::: :. * . ::: :: : * .* .: *. : * .*:** ****:***:: .:**::: * : :*. * :.: * ** :::* *:*.**:.::: *:** : : :**. :* .*. : * * .:* *:***: :**::: ...*: :****:*:* :: ::* : * . *::*****: :::. . ::*: * : * * * . * : . ", "identical_positions": 188, "similar_positions": 361, "identity": "10.76%" }, { "cls_id": "homologset.agr.SGD:S000001028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63116-1", "uniprot_id": "AAA1_RAT", "id": "P63116-1", "name": "Asc-type amino acid transporter 1", "aln": "------------------------------MRRDSDMASHIQQPGGHGNPGPAPSPSPGPGPGPGASE---RVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGS-VGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCI-PPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQI----FQGHFEELRPTNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSS-NAVAVTFGEKLLGYFS--WVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAM-IHVRRCTPIPALLVCCGATAVIMLVG-----DTYTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLVPVVYLVFWAFLLVFSFISEP------MVCGVGIIIILTGVPIFFLGVFWR--SKPKCVHRFTESMTRWGQELCFVVYPQ----GSLE-----EEENGPMGQPSPLPITDKPLKTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63115-1", "uniprot_id": "AAA1_MOUSE", "id": "P63115-1", "name": "Asc-type amino acid transporter 1", "aln": "------------------------------MRRDSDMASHIQQPGGHGNPGPAPSPSPGPGPGPGASE---RVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGS-VGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCI-PPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQI----FQGHFEELRPTNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSS-NAVAVTFGEKLLGYFS--WVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAM-IHVRRCTPIPALLVCCGATAVIMLVG-----DTYTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLVPVVYLVFWAFLLVFSFISEP------MVCGVGIIIILTGVPIFFLGVFWR--SKPKCVHRFTESMTRWGQELCFVVYPQ----GSLE-----EEENGPMGQPSPLPITDKPLKTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QXW9-1", "uniprot_id": "LAT2_MOUSE", "id": "Q9QXW9-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "------------------------------MEKGARQRNNTAK--NHP--GSDTSPEAEASSGGGG------VALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGS-VGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCF-PPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQI----CKGEFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLAS-NAVAVTFGEKLLGVMA--WIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM-IHVKRCTPIPALLFTCLSTLLMLVTS-----DMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKVSLLFPIIYLLFWAFLLIFSLWSEP------VVCGIGLAIMLTGVPVYFLGVYWQ--HKPKCFNDFIKSLTLVSQKMCVVVYPQEGNSGAEETTDDLEEQHKPIFKPTPVKDPDSEEQP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVR6-1", "uniprot_id": "LAT2_RAT", "id": "Q9WVR6-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "------------------------------MEKGTRQRNNTAK--NHPDRGSDTSPEAEASSGGGG------VALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGS-VGLALIVWIVTGVITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCF-PPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGVVQI----CKGEFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLAS-NAVAVTFGEKLLGVMA--WIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM-IHVKRCTPIPALLFTCLSTLLMLVTS-----DMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKISLLFPIIYLLFWAFLLIFSLWSEP------VVCGIGLAIMLTGVPVYFLGVYWQ--HKPKCFNDFIESLTLVSQKMCVVVYPQEGDSGTEETIDDVEEQHKPIFQPTPVKDPDSEEQP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4KHK8-1", "uniprot_id": "A0A0B4KHK8_DROME", "id": "A0A0B4KHK8-1", "name": "Y+L amino acid transporter 2", "aln": "------------------------------METESLNRKNSSRKSSIVNGNGDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGS-VNLALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECT-PPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQL----YLGNTQYFTFEN-----TDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGS-SAVAVTYAERAFGMLA--WTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTM-IQIQRFTPTPAVLAMALLSMLYLTVS-----DIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASP------VETGYGILMILSSIPVYLVFIAWK--NKPIWFQKTMVSLTRFLQKMLMVLGKQ--------------------TKPAQV----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z127-1", "uniprot_id": "LAT1_MOUSE", "id": "Q9Z127-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "----------------------------MAVAGAKRRAVATPAAAAAEEERQAREKMLEARRGDGADPEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGS-PGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCP-VPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDMGQGDASNLQQKLSFEG-TNLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLGVMS--WIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSM-IHPQLLTPVPSLVFTCIMTLMYAFSR-----DIFSIINFFSFFNWLCVALAIIGMMWLRFKKPELERPIKVNLALPVFFILACLFLIAVSFWKTP------MECGIGFAIILSGLPVYFFGVWWK--NKPKWILQAIFSVTVLCQKLMQVVPQET-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63016-1", "uniprot_id": "LAT1_RAT", "id": "Q63016-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "----------------------------MAVAGAKRRAVAAPATTAAEEERQAREKMLEARRGDGADPEGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAGS-PGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCP-VPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDIGQGDASNLHQKLSFEG-TNLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLGVMS--WIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSM-IHPQLLTPVPSLVFTCVMTLMYAFSR-----DIFSIINFFSFFNWLCVALAIIGMMWLRFKKPELERPIKVNLALPVFFILACLFLIAVSFWKTP------LECGIGFAIILSGLPVYFFGVWWK--NKPKWILQVIFSVTVLCQKLMQVVPQET-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGK6-1", "uniprot_id": "YLAT2_MOUSE", "id": "Q8BGK6-1", "name": "Y+L amino acid transporter 2", "aln": "---------------------------------MEAQELGSPTPTYHLLPKANQHTVKEDAGSPSQG-SPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTAS-YGLSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCD-PPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKL----CQGHTEHFQD--AFKG-SSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFGMFS--WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSM-IHIERFTPVPALLFNCTMTLIYLVVK-----DVFLLINYFSFSYWFFVGLSVVGQLYLRWKEPDWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDT------INSLIGIGIALSGVPVYFLGVYLPESRRPLFIRNVLATVTRVTQKLCFCVLTELD----------VTEEKNVERKTD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMM8-1", "uniprot_id": "YLAT2_RAT", "id": "D3ZMM8-1", "name": "Y+L amino acid transporter 2", "aln": "---------------------------------MEARELGSPTPTYHLLPKANQHTVKEDASSPSQG-SPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTAS-YGLSLVVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCD-PPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKL----CQGHTEHFQD--AFKG-SSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFGMFS--WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSM-IHIERFTPVPALLFNCTMTLIYLVVK-----DVFLLINYFSFSYWFFVGLSVVGQLYLRWKEPDWPRPLKLSLFFPIVFCICSLFLVAVPLFSDT------INSLIGIGIALSGVPVYFMGVYLPEARRPLFIRKVLATVTRVTQKLCFCVLTELD----------VAEEKNVERKTD------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1K8-1", "uniprot_id": "YLAT1_MOUSE", "id": "Q9Z1K8-1", "name": "Y+L amino acid transporter 1", "aln": "---------------------------------------MVNSTKYEVAAQHEAD--DGSALGDGASPVAEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSAS-FGLSLVIWAVGGIFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAVIAITFANYMVQPLFPSCG-APYAAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIIAGIVRL----GQGATANFEN--SFEG-SSFAMGDIALALYSALFSYSGWDTLNYVTEEIRNPERNLPLSIGISMPIVTIIYLLTNVAYYSVLDIKEILAS-DAVAVTFADQIFGVFN--WIIPVAVAFSCFGGLNASIVAASRLLFVGSREGHLPDAICM-VHVERFTPVPSLLFNGVLSLVYLCVE-----DIFQLINYYSFSYWFFVGLSIVGQLYLRWKDPDRPRPLKLSLFFPIIFCLCTIFLVAVPLYSDT------INSLIGIGIALSGLPFYFFIIRVPEHKRPLFLRRIVASITRYLQILCMSVAAEMD----------LEDGELSKQDPKSK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0S5-1", "uniprot_id": "YLAT1_RAT", "id": "Q9R0S5-1", "name": "Y+L amino acid transporter 1", "aln": "---------------------------------------MVASTKYEVAAQNEADEADGSAQGDGAGPAAEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSAS-FGLSLVIWAVGGIFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAVIAITFANYMVQPLFPSCG-APYAAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIIAGIVRL----GQGATTNFED--SFEG-SSFAMGDIALALYSALFSYSGWDTLNYVTEEIRNPERNLPLSIGISMPIVTIIYLLTNVAYYSVLDIKDILAS-DAVAVTFADQIFGIFN--WTIPLAVALSCFGGLNASIVAASRLLFVGSREGHLPDAICM-IHVERFTPVPSLLFNGILALVYLCVE-----DIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSLFFPIVFCLCTIFLVAVPLYSDT------INSLIGIGIALSGLPFYFLIIRVPEHKRPLCLRRIVASTTRYLQIICMSVAAEMD----------LEDGELPKQGPKSK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q59I64-1", "uniprot_id": "YLAT2_DANRE", "id": "Q59I64-1", "name": "Y+L amino acid transporter 2", "aln": "------------------------------------------------------------------------MQLKKEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSAS-YGLSLVIWAIGGIFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQPLFPTCE-PPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKL----CQGFTINFED--SFQG-SSRDPGGIALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTIIYILTNVAYYAVLDMSAILAS-DAVAVTFADHTLGVMS--WTIPIAVALSCYGGLNSSIIAASRLFFVGAREGHLPDALSM-IHIERFTPVPALLFNCAMALIYLTVE-----DVFQLINYYSFSYWFFVGLSIAGQIYLRWKEPDRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDT------LNTLIGIAIALSGVPVYFLGIHLPESKRPPIITKLLSAITRFTQFTCFYVLTEMD----------TVD---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WTR6-1", "uniprot_id": "XCT_MOUSE", "id": "Q9WTR6-1", "name": "Cystine/glutamate transporter", "aln": "-----------------------------------MVRKPVVATISKGGYLQGNMSGRLPSMGDQEPPGQEKVVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGS-VGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFFIQCE-IPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQL----IKGQTHHFKD--AFSG-RDTSLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQS-SAVAVTFSERLLGKFS--LAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSM-IHVHKHTPLPAVIVLHPLTMVMLFSG-----DLYSLLNFLSFARWLFMGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDP------FSTGVGFLITLTGVPAYYLFIVWD--KKPKWFRRLSDRITRTLQIILEVVPEDSKEL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LY33-1", "uniprot_id": "A0ABK0LY33_RAT", "id": "A0ABK0LY33-1", "name": "Cystine/glutamate transporter", "aln": "MAERRNDSIHIWLGESLGNCNTTAYQDWQQSFVRWASRKPVVATISKGGYLQGNVSGRLPSVGDQEPPGHEKVVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGS-VGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFFIQCE-IPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQL----IKGQTHHFKD--AFSG-RDTNLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQS-SAVAVTFSERLLGKFS--LAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSM-IHVHKHTPLPAVIVLHPLTMIMLFSG-----DLYSLLNFLSFARWLFMGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDP------FSTGVGFLITLTGVPAYYLFIVWD--KKPKWFRRLSDRITRTLQIILEVVPEDSKEL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXA6-1", "uniprot_id": "BAT1_MOUSE", "id": "Q9QXA6-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "---------------------------------------MEETSLRRRREDE------KSTHSTELK----TTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTES-VGPCLIIWAACGILATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYSGCK-PPAVVVKLLAAAAILFITTVNALSVRLGSYVQNVFTAAKMVIVAIIIISGLVFL----AQG--NVKNFQNSFEG-TQTSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQS-QAVAVTFGDRVLYPAS--WVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSY-ISVKRLTPAPALIFYGIIAIIYIIPG-----DINSLVNYFSFAAWLFYGMTILGLVVMRFTRKDLERPIKVPLFIPIIVILVSLFLILAPIISEPA-----WEYLYCVLFILSGLIFYFLFVYYKFGWAQRISR----PVTKHLQMLMEVVPPEKDPE--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82252-1", "uniprot_id": "BAT1_RAT", "id": "P82252-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "---------------------------------------MEETSPRRRREDE------KSVHSTEPK----TTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTES-VGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYLGCR-PPAVVVKLLAAAAILLITTVNALSVRLGSYVQNVFTAAKLVIVAIIIISGLVLL----AQG--NVKNFQNSFEG-SQTSVGSISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQS-QAVAVTFGDRVLYPAS--WVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSY-ISVKRLTPAPALVFYGIIAIIYIIPG-----DINSLVNYFSFAAWLFYGMTILGLVVMRFTRKDLERPIKVPIFIPIIVILVSVFLILAPIISSPA-----WEYLYCVLFILSGLIFYFLFVHYKFRWAQKISR----PITKHLQMLMEVVPPEKDPE--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGJ2-1", "uniprot_id": "F1QGJ2_DANRE", "id": "F1QGJ2-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "---------------------------------------MEEDLKKTKANNGSVSRAVEAKNPDQPK----AAVLHQDVGLLSGICLIVGTMIGSGIFISPKAVLEGTGA-VGPCLCVWAACGVLATLGALCYAELGTMIIKSGGEYPYLMEGFGPVLAYLYSWTTIIVLKPSSFAIIALSCAEYASTPFYPGCT-PPQVVTKCLAAACILIITLVNCLSVKLAYRVQNFFTAAKLLIIIIIVVSGIVML----AQG--NTQNLRDPFAG-ATTSFGAIGLAFYNGLWAYDGWNQLNFITEELKNPYKNLPLAIIIGIPLVTVCYIMVNIAYFSVMTSTELLQS-SAVAVTFGDRVLYPLS--WIVPVFVVCSTFGAANGSCFTAGRLTYVAGREGHMVKIMSY-ISVKRYTPSPALMFNGIVSIIYIMPT-----DINTLINYFSFATWLFYGLTCLALIVMRFTRKDLKRPVKVPIVIPALVVVVSCYLVLAPIIDKPE-----WEYLYCTMFIVGGLLLYVPFIHYKFNWTRRLMR----PFTMHLQLLLQVVPPEKIE---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZI89-1", "uniprot_id": "D3ZI89_RAT", "id": "D3ZI89-1", "name": "", "aln": "---------------------------------------MERKEEKDGSDKPE-----GQEQGSGAA----GLTMKREIGLWSAVSMTAGCMIGSGIFMSPQGVLVYIGS-PGASLIIWATCGLLALLGALCYAELGSLVPESGGEYAYILRAFGSLPAFLVIYIIVLVGRPAAITAVSLSFAEYALAPFYPGCSSVPQVIVKIVACSCILVLLLINFWSSRMSTVLMNVCTAAKLFSLLVIVVGGAVGL----AQGRIPTESLLFAFHN-TTQQAGRIGMAFYQGLWSFDGWSNINTVIEEIKNPKQNLVWAVVIAIPLVTILYVLVNISYLLVMSPSEILTS-DAIAVTWGNQVLGSWA--WLVPLAVALSTFGAVNGGFFSGSRVCYAAAREGHMPQLMSM-IHVHRLTPAPALIFTTAVALLLVIPG-----NFSTFVNLLSFLSWLTYGTTFACLLYLRIKTRNLHHTYKVPTFIPVIMLLVSLYLVLAPIIDHPQ-----MEFLYIFLFVLTGFPVYFLLFHFQC--QSKCVQ----TATMHLQLLLEVAPTIKDH---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WN3-1", "uniprot_id": "S7A13_MOUSE", "id": "Q91WN3-1", "name": "Solute carrier family 7 member 13", "aln": "----------------------------------------------------------------MAMDSKKEIRLKRELGYFWGTNFLIINIIGAGIFVSPKGVLQHSSMNVGVSLCVWAVCAVLTLTSALCSAEIGITFPYSGAHYYFLKRCFGPLVAFLRLWTSLFLG-PGLIASQALLLAEYGVQPFYPSCS-APILPRKCLALAMLWIVGILNSRGVKELSWLQTVSSVLKVGILGVISLSGLFLLVR----GKKENVQRLQNAFDAEFPEVSQLIEAIFQGYFAFSGGGCFTCIAGELKKPSKTIPRCIFTGLPLVTVVYLLANISYLTVLTPQEMLSS-DAVALTWTDRVIPQFT--WTVPFAISASLFINLVINVLETSRVLYIASENGQLPLLFCA-LNVH-SSPFIAVLLIISMASILIVLT-----NLIDLINYLYFVVSIWTALSIIGILKLRYQEPNLHRPYKVFLPFTFIALGITLSLVLIPLVKSPK-----LHYIYVFLFLLSGLVFYVPLIHFK------VKFVWFQKLTCYLQLLFNICIPDVSDDHIHEES--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RKI7-1", "uniprot_id": "S7A13_RAT", "id": "Q5RKI7-1", "name": "Solute carrier family 7 member 13", "aln": "----------------------------------------------------------------MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTG-PGVLASQALLLAEYGIQPFYPSCS-APAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVT----GRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSS-DAVALTWTDRVIPQLT--WSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCST-LNVH-SSPFIAVLLDVSMGSIAIVLT-----NLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPK-----MQYIYVFLFFLGGLLFYVPLIHFK------LKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TCU3-1", "uniprot_id": "S7A13_HUMAN", "id": "Q8TCU3-1", "name": "Solute carrier family 7 member 13", "aln": "------------------------------------------------------------------MDRGEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLG-SGVVAGQALLLAEYSIQPFFPSCS-VPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIR----GKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVVYLLVNISYLTVLTPREILSS-DAVAITWADRAFPSLA--WIMPFAISTSLFSNLLISIFKSSRPIYLASQEGQLPLLFNT-LNSH-SSPFTAVLLLVTLGSLAIILT-----SLIDLINYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPN-----VHYVYVLLLVLSGLLFYIPLIHFK------IRLAWFEKMTCYLQLLFNICLPDVSEE--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VIE6-1", "uniprot_id": "S7A12_MOUSE", "id": "Q8VIE6-1", "name": "Solute carrier family 7 member 12", "aln": "------------------------------------------------------------------------MQLLRALGVFHVSMILFSATLGTGIFVTPKAVLKYSSLNIPVSLSIWAGCGLLSIMSALCNAEIATTYPLSGASYYFLKRTLGSSVAFLSLWIKLFAH-FLGIGAQCLLIATSVIQCFYSGCP-APELPTKCLALAILWSFGIVSARGIKTVAWFNTVSSFIKLSVLCLISLT--VLLVN----GKKENVSRFENALDAELPNASQIADAILQVSYSYLGSSVLIVIAGEIKRPTETIPKTLIYGISIVTVLYLLTNISYLAVLTSQEIIFS-DSVGVTWMNRVFPSIQ--WISSFLISAFLLGSVSCGIVSASRVFYSASQEGEFPSIYSM-LNDH-HSPAVADIQIVILSSVAIISS-----SIIYLVKYVSLGSFCINLLQMIGLLKIRYQNPDIPRPYKVWLPFIFGSIALSLFLIFTPVIQSPS-----IEHVYQVVFLFCGFLCYWLQANLN------GHATCFDTITCYCQLLFNISPSEDPEEQKN-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M163-1", "uniprot_id": "F1M163_RAT", "id": "F1M163-1", "name": "", "aln": "----------------------------------------------------------------LALKKGKTMRLSRTVGFFHVTMVLLGTIIGTGIFVSPKGVLKYSSLNIPVSLGIWAGCGLLVMLNALSLVELATTFPVSGASYYFLKRSLGSLAAFLSLWIQLFSY-CLGLGAHTLLIATYLIQPFYTGCP-APELPIKCLSVAILWSFGILNAGGVKTVAWLQTISSMIKMSILCFISLTGLVLLVI----GKKENVSKFENALDAELPNASQTVEAILQGCFAYRGIFIVINIAGEIKNPSKIIPKAVISCLSITIMSYLLANVAYLTVLTPKEITTS-DSVVITWVNRAYPSMQ--WVMSLGISLSSLTTTACGILSAARICYSASLEGQMPFIFSM-LNNH-QSPVVAVTQVVILSTVSIICS-----NLTYLIKYLGIMSIFNDVLYMIAILKLRYQKPALPRPYKVCLPLVFGSLALSSFFILAPIIQSPN-----IEHIYEGLFLLSGFVVYWLQVYLY------QHADHFKTITCYLQLLFNVLPSDEQDKNLCSE---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "--------------MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVTDD----SWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHKNEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :*:*** * :* : .* . . . *:. : . :: : : . : :: : : . *: : : : * :: :.: * . : *: * : : . * : *::: : : : : .. : .* :* : :* : . ::. * : . .. . . . : * : ", "identical_positions": 20, "similar_positions": 69, "identity": "3.36%" }, { "cls_id": "homologset.agr.SGD:S000001031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WC0-1", "uniprot_id": "SETD3_MOUSE", "id": "Q91WC0-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPSPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKESFT-----------------------------YEDYRWAVSSVMTRQN-QIPTED-----GSRVTLALIPLWDMCNHT-NGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNN----SHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHSTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNAEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKIVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAVNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLPLVLRKLEEEAGVQESLSLTETVSKVKAAENGLVNGENLIPNGTRSENE----------------SLSPEESENVTG--EESSGSMAKVKERL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6U9-1", "uniprot_id": "SETD3_RAT", "id": "G3V6U9-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSILGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFT-----------------------------YEDYRWAVSSVMTRQN-QIPTED-----GSRVTLALIPLWDMCNHT-NGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNN----SHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKTVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAMNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLPLVLRKLEEEAGVQESLSLTETVSKVKAAENGLVNGESLIPNGTRSENE----------------SLSPEESENTTGDTEESSGSMDAVKERL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVD3-1", "uniprot_id": "SETD4_HUMAN", "id": "Q9NVD3-1", "name": "SET domain-containing protein 4", "aln": "---------MQKGKGRTSRIRRR----------KLCGSSE---------------------------SRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEE-QRAHVQEFFASSRDFFSSLQPLFAEAVDSIFS-----------------------------YSALLWAWCTVNTRAV-YLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHN----PHACVYVSR--------------------------------------EILVKYLPSTDKQMDKKISILKDHGYIENLTFG-------WDGPS--WRLLTALKLLCLEAEKFTCWK------------------KVLLGEVISDTNEKTSLDIAQKICYYFIEETN---------------------------------------AVLQKVSHMKDEKEALINQLTLVESLWTEELK----------------ILR------------ASAETLHSLQTAFT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38732-1", "uniprot_id": "EFM1_YEAST", "id": "P38732-1", "name": "Protein-lysine N-methyltransferase EFM1", "aln": "---------------------------------------------------------------------MITQTELDNCLQWAQNNGAFIDPKISFRITEDAGVSAFVNEKFSPKPDQALIRVPETLLITSQQALSEFSQAANERSLLNSVTQLYLSKLKFGTDAVHLKSFYKPYLDVLPLHLPQPYFWSTDEVMNLHGTDVYLTMRDTLNKLVKEWRMLFQALSIEHSSQDKQFLSLFQENKDSAVVPLEQFCAHINGCKLEDSEWNSFVAYLWSYCIFNSRAFPRVILGRAGTDRTNLNEGFLYPIVDLLNHKNDVPVRWEMNEQNELCFMSQTTTFSAQDELFNNYGNISNEKCLLNYGFWDSSNKFDFSRLTLKLPSTLVSGLPVDFNKSGNFVTDDGETTILQFSLKISEPLPPVLLALFAYLSKLKSEETPTVRSVLEGIDQLTSVVSQRLLFYKNFKIKTSSTQKLRPHVIKLIKLYYQDNKKILN--ATTEKLSVLQKKIYSNNKEFSLSFKTIFKNDKIFANSLLLVFGAINYEDLITKDCLNDALLLWIVKLINDKSNNQGGFIKQTFKEVSDSIVIEKEDVMEFLPFYKKYFPNLSERIPEIYSVGDWGIRQFIVADTAIDRLVWIRKSNKEPIFLMKKAYDLQI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : : .: . . : . : : :: :*.. *:* : . . . : : . . . .*:::**:: ** * . : * * : : . : . :. . . * : *: . . :* : . * * *: **. . : * : . : :::: ** .* . .:. ** * .: : : :*. : : . : :* :.. :: * . * .: .: : : :. : . : :: ::: : . . : : . .: :: ", "identical_positions": 30, "similar_positions": 112, "identity": "4.57%" }, { "cls_id": "homologset.agr.SGD:S000001043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZF1-1", "uniprot_id": "OSBL8_HUMAN", "id": "Q9BZF1-1", "name": "Oxysterol-binding protein-related protein 8", "aln": "-----------------------------------------------MEGG----LADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQR---------------QGKEAYP-TPTKDLHQPSLSPASPHSQGFER-------------GKEDISQNKDESSLSMSKSKSESKLYNGSE--------KDS-STSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWIHPR--------------------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGED------YVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGK-EVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGY-SSP--EPDIQDSSGSEAQSVKPSTR------------------RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPATDYFLQQ-----------------KDYFIIFLLILLQVIINFMFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H0X9-1", "uniprot_id": "OSBL5_HUMAN", "id": "Q9H0X9-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "------------------------------------------------------------MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSG-----------------DNELYPLSPGKDMEPN--GPSLPRDEGPP------------------------TPSSATKVPPAEYRLCNGSD--------KECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESDTETQDHSRKTE-SGSDQSETPG------APVR--RGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHPQ--------------------------------TDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAED------YTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKAS-DQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSP---------------RSWFLLCVFLACQLFINHILK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4JCZ0-1", "uniprot_id": "A0A0B4JCZ0_DROME", "id": "A0A0B4JCZ0-1", "name": "Oxysterol-binding protein", "aln": "MQQPATPSTPVNNAPSATPSAASGPAASAPAVASSTPIRINSAKQQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSVPTGGHLLQLQAPLPSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLRSNSSTGTAPTSSYIGEPLPVSHETQWSEADYEKHFNDHDLDAD--------------SQNEAPNAVMSGLESESESDPAEPAQDDVVDQQC------------VETSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKG--LKKPYNPILGERFRCYWQHP---------------------------------SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGEC------YTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGK-ETLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSYG-QWLYKYADLRPWDSRNDVRQYECQFKVLT---QTRHKSVPIVHGAEMIHPLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALIGLAFSLILRWLFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38755-1", "uniprot_id": "OSH7_YEAST", "id": "P38755-1", "name": "Oxysterol-binding protein homolog 7", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALNKLKNIP-----------------------------------------------------SLTNSSHSSINGIASNAANSKPSGADTDDIDEND--------------------------------------ESGQSILLNIISQLKPGCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGWHIGPRA--VKKPLNPILGEHFTAYWDLP---------------------------------NKQQAFYIAEQTSHHPPESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMRIELGDHMVIMGPK--YQVDIEFKTKGFISG--TYDAIEGTIKDYDGKEYYQISGKWNDIMYIKDLREKSSKKTVLFDT-HQHFPLAPKVRPLEEQGEYESRRLWKKVTDALAVRDHEVATEEKFQIENRQRELAKKRAEDGVEFHSKLFRRAEPGEDLDYYIYKHIPEGTDKHEEQIR-----------SILETAPILPGQTFTEKFSIPAYKKHGIQKN--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "F1LRE5-1", "uniprot_id": "F1LRE5_RAT", "id": "F1LRE5-1", "name": "Oxysterol-binding protein", "aln": "-----------------------------------------------------------------------------------------------------------------------MASIVEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKDDEQRKKVETLKDTTNSMVESIKHCIVLLQIAKDQSNAEQHADGVLSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPAQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGNSPPSSSLTPPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPD----TTESLNSSMSNGTSDADLFDSHDDRDEDGEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPRDRMVQVVKWYLSAFHAGRRGSVAKKPYNPILGEIFQCHWTLPNDTEENAELVS--------------EGPVPWVSK-NSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLEYGEH------YILTFPNGYGRSILT-VPWVELGGECSINCSKTGYSANIVFHTKPFYGGKKHRITAEIFSPNDK-KSFCSIEGEWNGIMYAKYATGENTVFVDTKKLPIIKKKVR----KLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGTVKH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A8Z1-1", "uniprot_id": "OSBL9_MOUSE", "id": "A2A8Z1-1", "name": "Oxysterol-binding protein-related protein 9", "aln": "-----------------------------------------------------------------------------------------------------------------------MASIVEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFIPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKDDEQRKKVETLKDTTNSMVESIKHCIVLLQIAKDQSNAEQHADGIISTINPVDAIYQPSPLEPVISTMPSQTALPPEPAQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGNSPPSSSLTPPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPD----TTESLNSSMSNGTSDADLFDSHDDRDDDGEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPRDRMVQVVKWYLSAFHAGRRGSVAKKPYNPILGEIFQCHWTLPNDTEENAELVS--------------EGPVPWVSK-NSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLEYDEH------YILTFPNGYGRSILT-VPWVELGGECNINCSKTGYSANIVFHTKPFYGGKKHRITAEIFSPNDK-KSFCSIEGEWNGIMYAKYATGENTVFVDTKKLPIIKKKVR----KLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAVKH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "S4R1M9-1", "uniprot_id": "OSB10_MOUSE", "id": "S4R1M9-1", "name": "Oxysterol-binding protein-related protein 10", "aln": "--------------------------------------------MERAAQSTDGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGG-GSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQSRYFVLDFEAGLLQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSKEKQLWVTQLRACAKYHMEMSSKTTPGSRSRSLTLLPHGTPSSASP---CSQRHLSTGAPGVVSVTRHKSPAA-ARRAKSQYSG------QLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLS------------LLQQSVRQAAPPSHKPGASETILGWHGPTSHS---------------------TDQLKNG-TLGSLPSASANITWAILPNSAEEEHNSQP----EPEPD-SGPELVLSEEEQSDNEDKGEVE--PGAMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKWTSPHPP------ISAHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEE------YVFTLPSAYARSILT-VPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTN-TIVCKAHGEWNGTLEFTYSNGE-TKVIDTTTLPVYPKKLR----PLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEERQRVEERKRETLRTPWRPKYFIPEGDGWVYFNPLWKTH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWM8-1", "uniprot_id": "F1LWM8_RAT", "id": "F1LWM8-1", "name": "Oxysterol-binding protein", "aln": "--------------------------------------------MERAAQSADGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGG-GSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSREKQLWVTQLRACAKYHMETSSKTTPGSRSRSLTLLPHGTPSSASP---CSQRHLSAGAPGVVSVTRHKSPAA-ARRAKSQYSG------QLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLT------------LLQQSVRQAGPPSHKPGASESILGWHGPTSQS---------------------TDQLKNG-TLGSLPSASANITWAILPNSAEEEHSSQP----EPEPD-SGPELVLSEEEQSDHEDKGEVE--PGTVEDQHSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKWTSPHPP------ISCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEE------YVFTLPSAYARSILT-VPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTN-TIVCKAHGEWNGTLEFTYSNGE-TKVIDTTTLPVYPKKLR----PLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEEKQRTEERKRETLRTPWRPKYFIPEGDGWVYFNPLWKTH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI95-1", "uniprot_id": "OSB11_MOUSE", "id": "Q8CI95-1", "name": "Oxysterol-binding protein-related protein 11", "aln": "-----------------------------------------------------MQGGEPASVMKVSESEGKLEGLATAVTPN-----KNSGNSSCGGAISSSSSNSSRGGSAKGWQYSDHMESVNGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLAS----SGNSP---ISQRRPSQNAMSFFNVGHSKLQS--VNKRAHLHPD------HLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDLLMLKATSMATMNCLNDCFH------------ILQL---QHASHQKGALPSGTTIEWLEPKIPL---------------------SNHYKNGAEQPFATEPN-KPMGAPEAQCVAESGVLAR----EPED-------ISADDEVEDTCDNKEDD--LGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLCLLEHGEE------YTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNLTN-TVVCRVQGEWNSVLEFTYSNGE-TKFVDLAKLAVTKKRVR----PLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLRTETGTPWKTKYFIKEGDGWVYHKPLWK-------GIPSQPAE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UVT3-1", "uniprot_id": "A0A8N7UVT3_DANRE", "id": "A0A8N7UVT3-1", "name": "Oxysterol-binding protein", "aln": "--------------------------------------------------------------------------MQTEAVLE-----HHSGSQSSG-----------RTG-SKSWQYSDLMEKVDGYLMKYTNLVTGWQYRYFVLNNEAGLLEYFVN-EQSRNQKPRGSLPLGGAVISPSDEDSHTFTVNAISGEQYKLRASDAKERQHWVSRLQVCAQHHTEAMGKTNPPLQSRSLSMASQG--SGSSP---GSQHRISQNSNALLGLSQLQRGSSLYSSRKSLLPD------HLLEAREMMTQAQGQHRDLIQSIEGLPSSQGPSPLDQDLLLLKATSLATMTCLSDCLH------------ILQL---QQVARQKFPL-SGPALEWLEPKLP-----------------------DILKNGGTLPSITKDDGKTEGAVLEPLEMDSCDIVL----EQEE-------IDATQEVDDSSPSEEED--LGAVEEERSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFVAITDGSSPMDRMVRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWNVPK-EAASPTG-------------IPKEG-SSCASDCYNVRFVAEQVSHHPPVSGFYAECQERQMCVNTHVWTKSKFMGMSIGVSMIGEGNLNLLEHGEE------YTFSLPSAYARSILT-VPWVELGGKVNVNCAKTGYSAVITFQTKPFYGGKLHRVNAEVKHNPTN-AVVCRVQGEWNGVLEFAYTSGE-TRFVDVTKLPVTRKRVR----PNELQGPYESRRLWQHVTESLKERDMDKATEHKRFLEERQRKEERHRAETQTPWRTKYFERKGEGWMYYQPLWKTAGQSSSSVPSPQNP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. :*:: ::.*:: * **:::.****:** :*:*: :: ..*.: *. .: :**:.:: :. *** ***:** * . * * ::***.***** * :. : : . : .**:* * * .. * : * : * : * : :.** :***. : : : . : *: * * .. . *.*: : : * **. **: *: : : **: * :*: ** : * * . ", "identical_positions": 71, "similar_positions": 80, "identity": "6.67%" }, { "cls_id": "homologset.agr.SGD:S000001044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0K5-1", "uniprot_id": "GDC_MOUSE", "id": "Q8C0K5-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "--MAALVAAAALAAAEPAPAVPQAAGSGGPTSRRDF----------------------------------YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKH-----LGVLSTLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSG----HVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEG---------------GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--YAPALLGRPSSDN-------PNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLP---EFEKCLTMRETMKYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16261-1", "uniprot_id": "GDC_RAT", "id": "P16261-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "--MAALVAAAALAAAEPPPAVPQAAGSGGPTSRRDF----------------------------------YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKH-----LGVLSALRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSG----HVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEG---------------GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--YAPTLLGRPSSDN-------PNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLP---EFEKCLTMRETMKYVYGHHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16260-1", "uniprot_id": "GDC_HUMAN", "id": "P16260-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "--MAAATAAAALAAADPPPAMPQAAGAGGPTTRRDF----------------------------------YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKH-----LGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISG----HVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEG---------------GFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--HAPTLLGRPSSDN-------PNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP---EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6P1-1", "uniprot_id": "A0ACD6B6P1_DANRE", "id": "A0ACD6B6P1-1", "name": "", "aln": "------MTTEAVSSG----ARPQIP---APVQRDGY----------------------------------YWLRSFTAGGVAGCCAKSTIAPLDRVKILLQAQNPHYKH-----LGVFATIKAVPKKEGFLGLYKGNGAMMIRIFPYGAIQFMAFDNYKKFLHTKVGISG----HVHRLMAGSMAGMTAVICTYPLDVIRARLAFQVTGHHRYSGIRHAFQTIYHKEG---------------GISGFYRGLIPTIIGMAPYAGFSFFTFGTLKTLGLT--HFPEQLGKPSLDN-------PDVLVLKTQVNLLCGGVAGAIAQTISYPLDVARRRMQLGASLP---DHDKCCSLTKTLKHVYSQYGVKKGLYRGLSLNYIRCVPSQAVAFTTYEFMKQVLHLN--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38702-1", "uniprot_id": "LEU5_YEAST", "id": "P38702-1", "name": "Mitochondrial coenzyme A transporter LEU5", "aln": "------MTRDSPDSNDSYKHINKNTTQKTSFDRNSFD---------------------------------YIVRSGLAGGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFES----HWRRLVSGSLAGLCSVFITYPLDLVRVRLAYET--EHKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVR-GFFVGLSIGYIKVTPMVACSFFVYERMKWNFGI---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q0P483-1", "uniprot_id": "S2542_DANRE", "id": "Q0P483-1", "name": "Mitochondrial coenzyme A transporter SLC25A42", "aln": "MGNVVQERQGALAQG-------EVLPRPAASQSEGFKQGRS------------------------------VLNSLVSGAFAGAVAKTAVAPLDRTKIIFQVSSNR-FSAK----EAYRLIYRTYLKDGFFSLWRGNSATMVRVIPYAAIQFCAHEQYKGILGKYYGFQGKALPPVPRLLAGSLAGTTAAIITYPLDMVRARMAVTP-KEM-YSNIMDVFVRISREEG----------------LKTLYRGFTPTILGVVPYAGLSFFTYETLKKTHAEK---------------------TGRAHPFPYERLVFGACAGLIGQSASYPLDVVRRRMQTAGVT-----GHTYSTVLGTMREIVAEEGIVRGLYKGLSMNWVKGPIAVGISFMTFDLTQILLRKFQLL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDL7-1", "uniprot_id": "Q9VDL7_DROME", "id": "Q9VDL7-1", "name": "Mitochondrial coenzyme A transporter SLC25A42", "aln": "MSRLLEKPNIAMSIKSTGSQLSSTMTTASATLSSDLDDADTSRTQLSPSETSGVVLVPATTVTPMRQKIDQVVISLISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFR----ASLRYLQNTYANEGVLALWRGNSATMARIVPYAAIQFTAHEQWRRIL--HVDKDGTNTKGR-RFLAGSLAGITSQSLTYPLDLARARMAVTD-RYTGYRTLRQVFTKIWVEEG----------------PRTLFRGYWATVLGVIPYAGTSFFTYETLKREYYEV---------------------VGNNKPNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNT--AGGDRYPTILETLVKIYREEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLIKAWLTELANLRRVEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : * :*. :*. **: :***** *: :* . ::* .:::*:.* : *:.**.*::* *.:: : : .. *:::**:** : *****: *.*:* : : * : . ::** .*::*: **** ***:. *: . * *. ** .*: :**::: ***:* . :: : . *: *:: ***:.::: . :* .:: : : ", "identical_positions": 64, "similar_positions": 85, "identity": "15.53%" }, { "cls_id": "homologset.agr.SGD:S000001046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B7T6-1", "uniprot_id": "CNEP1_RAT", "id": "Q3B7T6-1", "name": "CTD nuclear envelope phosphatase 1", "aln": "---------------------------------------------------------------------------MMRT-QCLLGLRTFVAFAAKLWSFFIYL---------------------------------------------------------------------------LRRQIRTVIQYQTVRYDILP-LSPLSRNR--------------------------------------LAQVKRKILVLDLDETLIHSHHDG-VLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSR-SILKRRYYRQHCTLELGS-YIKDLSVV----------HSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TP92-1", "uniprot_id": "CNEP1_MOUSE", "id": "Q3TP92-1", "name": "CTD nuclear envelope phosphatase 1", "aln": "---------------------------------------------------------------------------MMRT-QCLLGLRTFVAFAAKLWSFFIYL---------------------------------------------------------------------------LRRQIRTVIQYQTVRYDILP-LSPLSRNR--------------------------------------LAQVKRKILVLDLDETLIHSHHDG-VLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSR-SILKRRYYRQHCTLELGS-YIKDLSVV----------HSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95476-1", "uniprot_id": "CNEP1_HUMAN", "id": "O95476-1", "name": "CTD nuclear envelope phosphatase 1", "aln": "---------------------------------------------------------------------------MMRT-QCLLGLRTFVAFAAKLWSFFIYL---------------------------------------------------------------------------LRRQIRTVIQYQTVRYDILP-LSPVSRNR--------------------------------------LAQVKRKILVLDLDETLIHSHHDG-VLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSR-SILKRRYYRQHCTLELGS-YIKDLSVV----------HSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U395-1", "uniprot_id": "CNEPA_DANRE", "id": "Q5U395-1", "name": "CTD nuclear envelope phosphatase 1A", "aln": "---------------------------------------------------------------------------MLKTRQCLLGIRTFLGVTSRIWSFFLYI---------------------------------------------------------------------------LRKHLRTIIQYQTVRYDILP-LSPISRNR--------------------------------------LNAVKRKILVLDLDETLIHSHHDG-VLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNNR-GILKRRYYRQHCTLDLGS-YIKDLSVV----------HSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTSDVRSVLSRNLHQHRLW--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5U3T3-1", "uniprot_id": "CNEPB_DANRE", "id": "Q5U3T3-1", "name": "CTD nuclear envelope phosphatase 1B", "aln": "---------------------------------------------------------------------------MLKTRQCLLGVRTFHGVTSRIWSFFLYI---------------------------------------------------------------------------LRKHIRTIIQYQTVRYDILS-LSPISRNR--------------------------------------LNNVKRKILVLDLDETLIHSHHDG-VLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNNK-AILKRRYYRQHCTLDSGS-YIKDLSVV----------HDDLSSVVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFPADVRSVLSRNLHQHRLW--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRG7-1", "uniprot_id": "CNEP1_DROME", "id": "Q9VRG7-1", "name": "CTD nuclear envelope phosphatase 1 homolog", "aln": "---------------------------------------------------------------------------MISLLQMKF--RALLLLLSKVWTCICFM---------------------------------------------------------------------------FNRQVRAFIQYQPVKYELFP-LSPVSRHR--------------------------------------LSLVQRKTLVLDLDETLIHSHHNA-MPRNTVKPGTPHDFTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWYDLVVFTASMEIYGAAVADKLDNGR-NILRRRYYRQHCTPDYGS-YTKDLSAI----------CSDLNRIFIIDNSPGAYRCFPNNAIPIKSWFSDPMDTALLSLLPMLDALRFTNDVRSVLSRNLHLHRLW--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZS0-1", "uniprot_id": "Q9VZS0_DROME", "id": "Q9VZS0-1", "name": "FCP1 homology domain-containing protein", "aln": "--------------------------------------------------------------------MQLKSEFLIIYVFGLATMGLMMGIACVVIPRLWFF---------------------------------------------------------------------------LEKVYRVFVEYTPIIYLSEDRLSPVSKSR--------------------------------------LSLVARKTLVLDMDNTMITSWFIKRGKKPKNIPRIAHDF--KFYLPAYGATIYVYKRPYLDHFLDRVSKWYDLTVFTSGAEIYASPILDFLDRGR-GILNSRLYRQHCIEQFGK-WSKSVLLA----------CPDLSNVVLLDNSSTECSFNAENAILIKSYEIGCRDEALINLLPFLDALRFMKDVRSMLKRCTRFESFAQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38757-1", "uniprot_id": "NEM1_YEAST", "id": "P38757-1", "name": "Nuclear envelope morphology protein 1", "aln": "MNALKYFSNHLITTKKQKKINVEVTKNQDLLGPSKEVSNKYTSHSENDCVSEVDQQYDHSSSHLKESDQNQERKNSVPKKPKALRSILIEKIASILWALLLFLPYYLIIKPLMSLWFVFTFPLSVIERRVKHTDKRNRGSNASENELPVSSSNINDSSEKTNPKNCNLNTIPEAVEDDLNASDEIILQRDNVKGSLLRAQSVKSRPRSYSKSELSLSNHSSSNTVFGTKRMGRFLFPKKLIPKSVLNTQKKKKLVIDLDETLIHSASRS---TTHSNSSQGHLVEVKFGLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSFPSSFSKRYYRSDCVLRDGVGYIKDLSIVKDSEENGKGSSSSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTDTDLLNLLPFLEAMRYSTDVRNILALKHGEKAFNIN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : . : :: :. . .:: : * *: * * :* **:*:*:*:* * . . *. : . :::***: * ** **:**:* :**:. : *. .: * *: . : * **..* * : *.: .*. :.::***. :*** ::.: . * *:.***:*:*:*: ***.:* . : ", "identical_positions": 54, "similar_positions": 71, "identity": "12.03%" }, { "cls_id": "homologset.agr.SGD:S000001047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04897-1", "uniprot_id": "GNAI2_RAT", "id": "P04897-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "-------MG-CTVS----------------AEDKAAAE-------------RSKM-----------------IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFA----------------------------------------------------------------------------------------DPQRADDARQ-LFALSCAAEEQ--------------------GMLPEDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQ--SPLTICFPEYTG-----------------ANKYDEAASYIQSKFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08752-1", "uniprot_id": "GNAI2_MOUSE", "id": "P08752-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "-------MG-CTVS----------------AEDKAAAE-------------RSKM-----------------IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFA----------------------------------------------------------------------------------------DPQRADDARQ-LFALSCAAEEQ--------------------GMLPEDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQ--SSLTICFPEYTG-----------------ANKYDEAASYIQSKFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04899-1", "uniprot_id": "GNAI2_HUMAN", "id": "P04899-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "-------MG-CTVS----------------AEDKAAAE-------------RSKM-----------------IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFA----------------------------------------------------------------------------------------DPSRADDARQ-LFALSCTAEEQ--------------------GVLPDDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITH--SPLTICFPEYTG-----------------ANKYDEAASYIQSKFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RSH2-1", "uniprot_id": "GNAI1_MOUSE", "id": "B2RSH2-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------DSARADDARQ-LFVLAGAAEE---------------------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKK--SPLTICYPEYAG-----------------SNTYEEAAAYIQCQFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63096-1", "uniprot_id": "GNAI1_HUMAN", "id": "P63096-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------DSARADDARQ-LFVLAGAAEE---------------------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKK--SPLTICYPEYAG-----------------SNTYEEAAAYIQCQFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10824-1", "uniprot_id": "GNAI1_RAT", "id": "P10824-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------DAARADDARQ-LFVLAGAAEE---------------------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKK--SPLTICYPEYAG-----------------SNTYEEAAAYIQCQFE-----------DLNKRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DC51-1", "uniprot_id": "GNAI3_MOUSE", "id": "Q9DC51-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------ESARADDARQ-LFVLAGSAEE---------------------GVMTSELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKR--SPLTICYPEYTG-----------------SNTYEEAAAYIQCQFE-----------DLNRRKDTKEVYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08753-1", "uniprot_id": "GNAI3_RAT", "id": "P08753-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------EAARADDARQ-LFVLAGSAEE---------------------GVMTSELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKR--SPLTICYPEYTG-----------------SNTYEEAAAYIQCQFE-----------DLNRRKDTKEVYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08754-1", "uniprot_id": "GNAI3_HUMAN", "id": "P08754-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "-------MG-CTLS----------------AEDKAAVE-------------RSKM-----------------IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFG----------------------------------------------------------------------------------------EAARADDARQ-LFVLAGSAEE---------------------GVMTPELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFK-MFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKR--SPLTICYPEYTG-----------------SNTYEEAAAYIQCQFE-----------DLNRRKDTKEIYT--HFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20353-1", "uniprot_id": "GNAI_DROME", "id": "P20353-1", "name": "G protein alpha i subunit", "aln": "-------MG-CAVST---------------ARDKEAIE-------------RSKN-----------------IDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFA----------------------------------------------------------------------------------------DPSRTDIARQ-FFTHASAADE---------------------GILLPEIVLLMKKLWA-DGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHFK-LFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKR--SPLTICFPEYTG-----------------TNTFEEAANYIRMKFE-----------NLNKRKDQKEIYT--HLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P59215-1", "uniprot_id": "GNAO_RAT", "id": "P59215-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "-------MG-CTLS----------------AEERAALE-------------RSKA-----------------IEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYG----------------------------------------------------------------------------------------DKERKADSKM-VCDVVSRMEDT--------------------EPFSAELLSAMMRLWG-DSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFR-LFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKK--SPLTICFPEYPG-----------------SNTYEDAAAYIQTQFE-----------SKNRSPN-KEIYC--HMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18872-1", "uniprot_id": "GNAO_MOUSE", "id": "P18872-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "-------MG-CTLS----------------AEERAALE-------------RSKA-----------------IEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYG----------------------------------------------------------------------------------------DKERKTDSKM-VCDVVSRMEDT--------------------EPFSAELLSAMMRLWG-DSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETHFTFKNLHFR-LFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKK--SPLTICFPEYPG-----------------SNTYEDAAAYIQTQFE-----------SKNRSPN-KEIYC--HMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09471-1", "uniprot_id": "GNAO_HUMAN", "id": "P09471-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "-------MG-CTLS----------------AEERAALE-------------RSKA-----------------IEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYG----------------------------------------------------------------------------------------DKERKADAKM-VCDVVSRMEDT--------------------EPFSAELLSAMMRLWG-DSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFR-LFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKK--SPLTICFPEYTG-----------------PNTYEDAAAYIQAQFE-----------SKNRSPN-KEIYC--HMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W442-1", "uniprot_id": "F8W442_DANRE", "id": "F8W442-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "-------MG-CTLS----------------AEERAALD-------------RSKA-----------------IEKNLKEDGITAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGDDVKQYKPVVYSNTIQSLAAIVRAMDTLGLEYG----------------------------------------------------------------------------------------DKERKADAKM-VCDVVSRMEDT--------------------EPYSPELLSAMIRLWS-DSGIQECFSRAREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFR-LFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESMKLFDSICNNKWFTNTSIILFLNKKDIFGDKIRK--SPLSICFPEYTG-----------------SNTFEEAVNYIQSQYE-----------SKNKSVE-KEIYS--HITCATDTDNIQFVFDAVTDVIIANNLRFCGLY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16378-1", "uniprot_id": "GNAO_DROME", "id": "P16378-1", "name": "G protein alpha o subunit", "aln": "-------MG-CAQS----------------AEERAAAA-------------RSRL-----------------IERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYS----------------------------------------------------------------------------------------NNERESDAKM-VFDVCQRMHDT--------------------EPFSEELLAAMKRLWQ-DAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFK-LFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRK--SPLTICFPEYTG-----------------GQEYGEAAAYIQAQFE-----------AKNKSTS-KEIYC--HMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O70443-1", "uniprot_id": "GNAZ_MOUSE", "id": "O70443-1", "name": "Guanine nucleotide-binding protein G(z) subunit alpha", "aln": "-------MG-CRQS----------------SEEKEAAR-------------RSRR-----------------IDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFH----------------------------------------------------------------------------------------NPDRAYDAVQ-LFALTGPAESK--------------------GEITPELLGVMRRLWA-DPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFK-MVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRR--IPLSVCFPEYKG-----------------QNTYEEAAVYIQRQFE-----------DLNRNKETKEIYS--HFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19627-1", "uniprot_id": "GNAZ_RAT", "id": "P19627-1", "name": "Guanine nucleotide-binding protein G(z) subunit alpha", "aln": "-------MG-CRQS----------------SEEKEAAR-------------RSRR-----------------IDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFH----------------------------------------------------------------------------------------NPDRAYDAVQ-LFALTGPAESK--------------------GEITPELLGVMRRLWA-DPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFK-MVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRR--IPLSVCFPEYKG-----------------QNTYEEAAVYIQRQFE-----------DLNRNKETKEIYS--HFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19086-1", "uniprot_id": "GNAZ_HUMAN", "id": "P19086-1", "name": "Guanine nucleotide-binding protein G(z) subunit alpha", "aln": "-------MG-CRQS----------------SEEKEAAR-------------RSRR-----------------IDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFH----------------------------------------------------------------------------------------NPDRAYDAVQ-LFALTGPAESK--------------------GEITPELLGVMRRLWA-DPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFK-MVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRR--IPLTICFPEYKG-----------------QNTYEEAAVYIQRQFE-----------DLNRNKETKEIYS--HFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50149-1", "uniprot_id": "GNAT2_MOUSE", "id": "P50149-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-2", "aln": "-------MG-SGIS----------------AEDKELAR-------------RSKE-----------------LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYA----------------------------------------------------------------------------------------EPSCADAGRQ-LNNLADSTEE---------------------GTMPPELVDVIRKLWK-DGGVQACFDRAAEFQLNDSASYYLNQLDRITDPNYLPNEQDVLRSRVKTTGIIETKFSVKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKK--VHLSICFPEYDG-----------------NNSYEDAGNYIKSQFL-----------DLNMRKDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA42-1", "uniprot_id": "D4AA42_RAT", "id": "D4AA42-1", "name": "", "aln": "-------MG-SGIS----------------AEDKELAK-------------RSRE-----------------LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYA----------------------------------------------------------------------------------------EPSCAEAGRQ-LNNLADSTEE---------------------GTMPSELVEVIRKLWK-DGGVQACFDRAAEFQLNDSASYYLNQLDRITDPDYLPNEQDVLRSRVKTTGIIETKFSVKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKK--VHLSICFPEYDG-----------------NNSYEDAGNYIKSQFL-----------DLNMRKDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19087-1", "uniprot_id": "GNAT2_HUMAN", "id": "P19087-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-2", "aln": "-------MG-SGAS----------------AEDKELAK-------------RSKE-----------------LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYA----------------------------------------------------------------------------------------EPSCADDGRQ-LNNLADSIEE---------------------GTMPPELVEVIRRLWK-DGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKTTGIIETKFSVKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKK--VHLSICFPEYDG-----------------NNSYDDAGNYIKSQFL-----------DLNMRKDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20612-1", "uniprot_id": "GNAT1_MOUSE", "id": "P20612-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-1", "aln": "-------MG-AGAS----------------AEEK-----------------HSRE-----------------LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYG----------------------------------------------------------------------------------------DSARQDDARK-LMHMADTIEE---------------------GTMPKEMSDIIQRLWK-DSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKK--AHLSICFPDYDG-----------------PNTYEDAGNYIKVQFL-----------ELNMRRDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSS5-1", "uniprot_id": "D3ZSS5_RAT", "id": "D3ZSS5-1", "name": "", "aln": "-------MG-AGAS----------------AEEK-----------------HSRE-----------------LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYG----------------------------------------------------------------------------------------DSARQDDARK-LMHMADTIEE---------------------GTMPKEMSDIIQRLWK-DSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKK--AHLSICFPDYDG-----------------PNTYDDAGNYIKVQFL-----------ELNMRRDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11488-1", "uniprot_id": "GNAT1_HUMAN", "id": "P11488-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-1", "aln": "-------MG-AGAS----------------AEEK-----------------HSRE-----------------LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYG----------------------------------------------------------------------------------------DSARQDDARK-LMHMADTIEE---------------------GTMPKEMSDIIQRLWK-DSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKK--AHLSICFPDYDG-----------------PNTYEDAGNYIKVQFL-----------ELNMRRDVKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V3I2-1", "uniprot_id": "GNAT3_MOUSE", "id": "Q3V3I2-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "-------MG-SGIS----------------SESKESAR-------------RSKE-----------------LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMATLGIDYV----------------------------------------------------------------------------------------NPRSREDQEQ-LHSMANTLED---------------------GDMTPQLAEIIKRLWG-DPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVAK--VHLSICFPEYTG-----------------PNTFEDAGNYIKNQFL-----------DLNLKKEDKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29348-1", "uniprot_id": "GNAT3_RAT", "id": "P29348-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "-------MG-SGIS----------------SESKESAK-------------RSKE-----------------LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYV----------------------------------------------------------------------------------------NPRSREDQQL-LLSMANTLED---------------------GDMTPQLAEIIKRLWG-DPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTK--VHLSICFPEYTG-----------------PNTFEDAGNYIKNQFL-----------DLNLKKEDKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MTJ3-1", "uniprot_id": "GNAT3_HUMAN", "id": "A8MTJ3-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "-------MG-SGIS----------------SESKESAK-------------RSKE-----------------LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYV----------------------------------------------------------------------------------------NPRSAEDQRQ-LYAMANTLED---------------------GGMTPQLAEVIKRLWR-DPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFR-MFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTK--VHLSICFPEYTG-----------------PNTFEDAGNYIKNQFL-----------DLNLKKEDKEIYS--HMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "-------MG-CTVSTQT-----------IGDESDPFLQ-------------NKRAN--------------DVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFK-VLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKS--MPIRKYFPDYQG----------------RVGDAEAGLKYFEKIFL-----------SLN--KTNKPIYV--KRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8CGK7-1", "uniprot_id": "GNAL_MOUSE", "id": "Q8CGK7-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "-------MG-CLGNSS------------KTAEDQGVDE-------------KERR------------EANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVP----------------------------------------------------------------------------------------LANPENQFRSDYIKSIAPITD---------------------FEYSQEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFH-MFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP---EDATPDAGE-DPKVTRAKFFIRDLFL-----------RISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38406-1", "uniprot_id": "GNAL_RAT", "id": "P38406-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "-------MG-CLGNSS------------KTAEDQGVDE-------------KERR------------EANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGSNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVP----------------------------------------------------------------------------------------LANPENQFRSDYIKSIAPITD---------------------FEYSQEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFH-MFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP---EDATPDAGE-DPKVTRAKFFIRDLFL-----------RISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38405-1", "uniprot_id": "GNAL_HUMAN", "id": "P38405-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "-------MG-CLGGNS------------KTTEDQGVDE-------------KERR------------EANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVP----------------------------------------------------------------------------------------LANPENQFRSDYIKSIAPITD---------------------FEYSQEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFH-MFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP---EDATPDAGE-DPKVTRAKFFIRDLFL-----------RISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZ01-1", "uniprot_id": "A0A8M1PZ01_DANRE", "id": "A0A8M1PZ01-1", "name": "Guanine nucleotide-binding protein G(s) subunit alpha", "aln": "-------MGMCHSFRSRLSESAITYTGGRSAAGAGIDAESGGHSDSCDPQLRERRRAEERARVKAENKRSRNIDKSLKAEKREYKQTHRLLLLGAGESGKSTIVKQMRILHVNGFNAEEKKQKIQDIKNNIKEAIETIVTAMSVLVPPVQ----------------------------------------------------------------------------------------LACPANKFRIDYILNLANQKD---------------------FEFTTEFYEHTKTLWQ-DEGVKACFERSNEYQLIDCAQYFLDRIDTVKQSDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFH-MFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVLREDNQTNRLQEALNLFKNIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTP---DDATPEQGE-DPRVTRAKYFIRDEFL-----------RISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20354-1", "uniprot_id": "GNAS_DROME", "id": "P20354-1", "name": "G protein alpha s subunit", "aln": "-------MG-CFGSPTS-----------KQSDVNSEDS-------------KSQK------------RRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVA----------------------------------------------------------------------------------------LEKKENEPRVEYIQDYASSPD---------------------FNYPPEFYEHTEELWK-DKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFH-MFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESND-DPEVIRAKYFIRDEFL-----------RISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50148-1", "uniprot_id": "GNAQ_HUMAN", "id": "P50148-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIM-------ACCLSEEAKEARR-------------INDE-----------------IERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYK----------------------------------------------------------------------------------------YEHNKAHAQLVREVDVEKVSAFE-----------------------NPYVDAIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMY--SHLVDYFPEYDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21279-1", "uniprot_id": "GNAQ_MOUSE", "id": "P21279-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIM-------ACCLSEEAKEARR-------------INDE-----------------IERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYK----------------------------------------------------------------------------------------YEHNKAHAQLVREVDVEKVSAFE-----------------------NPYVDAIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMY--SHLVDYFPEYDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82471-1", "uniprot_id": "GNAQ_RAT", "id": "P82471-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIM-------ACCLSEEAKEARR-------------INDE-----------------IERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMVRAMDTLKIPYK----------------------------------------------------------------------------------------YEHNKAHAQLVREVDVEKVSAFE-----------------------NPYVDAIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMY--SHLVDYFPEYDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JID2-1", "uniprot_id": "GNA11_RAT", "id": "Q9JID2-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMI-------ACCLSDEVKESKR-------------INAE-----------------IEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAVVRAMDTLKIRYK----------------------------------------------------------------------------------------YEQNKANALLIREVDVEKVTTFE-----------------------HQYVNAIKTLWS-DPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQHSSVILFLNKKDLLEDKILH--SHLVDYFPEFDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21278-1", "uniprot_id": "GNA11_MOUSE", "id": "P21278-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMM-------ACCLSDEVKESKR-------------INAE-----------------IEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYK----------------------------------------------------------------------------------------YEQNKANALLIREVDVEKVTTFE-----------------------HQYVNAIKTLWS-DPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILH--SHLVDYFPEFDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29992-1", "uniprot_id": "GNA11_HUMAN", "id": "P29992-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMM-------ACCLSDEVKESKR-------------INAE-----------------IEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYK----------------------------------------------------------------------------------------YEQNKANALLIREVDVEKVTTFE-----------------------HQYVSAIKTLWE-DPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILY--SHLVDYFPEFDGP----------------QRDAQAAREFILKMFV------------DLNPDSDKIIYS--HFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8XRQ3-1", "uniprot_id": "A0A8J8XRQ3_RAT", "id": "A0A8J8XRQ3-1", "name": "Guanine nucleotide-binding protein subunit alpha", "aln": "---------------MAG-------CCCLSAEEKESQR-------------ISAE-----------------IERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYT----------------------------------------------------------------------------------------CEQNKENAQIIREVEVDKVSAIS-----------------------RDQVAAIKQLWL-DPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMY--SHLISYFPEYTGP----------------KQDVKAARDFILKLYQ------------DQNPDKEKVIYS--HFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30677-1", "uniprot_id": "GNA14_MOUSE", "id": "P30677-1", "name": "Guanine nucleotide-binding protein subunit alpha-14", "aln": "---------------MAG-------CCCLSAEEKESQR-------------ISAE-----------------IERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYM----------------------------------------------------------------------------------------CEQNKENAQIIREVEVDKVTALS-----------------------RDQVAAIKQLWL-DPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMY--SHLISYFPEYTGP----------------KQDVKAARDFILKLYQ------------DQNPDKEKVIYS--HFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95837-1", "uniprot_id": "GNA14_HUMAN", "id": "O95837-1", "name": "Guanine nucleotide-binding protein subunit alpha-14", "aln": "---------------MAG-------CCCLSAEEKESQR-------------ISAE-----------------IERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYV----------------------------------------------------------------------------------------CEQNKENAQIIREVEVDKVSMLS-----------------------REQVEAIKQLWQ-DPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMY--SHLISYFPEYTGP----------------KQDVRAARDFILKLYQ------------DQNPDKEKVIYS--HFTCATDTDNIRFVFAAVKDTILQLNLREFNLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88302-1", "uniprot_id": "GNA15_RAT", "id": "O88302-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "-------MARS-LTWGCC-------PWCLTEEEKTAAR-------------IDQE-----------------INKILLEQKKQERGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEDRRAFRLLVYQNIFVSMQAMIEAMDRLQIPFS----------------------------------------------------------------------------------------RPDSKQHASLVMTQDPYKVSSFE-----------------------KPYAVAMQYLWR-DAGIRACYERRREFHLLDSAVYYLSHLERIAEDDYIPTAQDVLRSRMPTTGINEYCFSVQKTKLR-IVDAGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENSQENRMKESLALFSTILELPWFKSTSVILFLNKTDILEDKIHT--SHLASYFPSFQGP----------------RRDAEAAKRFILDMYARVYASCAEPHDGGRKGSRARRLFA--HFTCATDTHSVRSVFKDVRDSVLARYLDEINLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30678-1", "uniprot_id": "GNA15_MOUSE", "id": "P30678-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "-------MARS-LTWGCC-------PWCLTEEEKTAAR-------------IDQE-----------------INRILLEQKKQEREELKLLLLGPGESGKSTFIKQMRIIHGVGYSEEDRRAFRLLIYQNIFVSMQAMIDAMDRLQIPFS----------------------------------------------------------------------------------------RPDSKQHASLVMTQDPYKVSTFE-----------------------KPYAVAMQYLWR-DAGIRACYERRREFHLLDSAVYYLSHLERISEDSYIPTAQDVLRSRMPTTGINEYCFSVKKTKLR-IVDVGGQRSERRKWIHCFENVIALIYLASLSEYDQCLEENDQENRMEESLALFSTILELPWFKSTSVILFLNKTDILEDKIHT--SHLATYFPSFQGP----------------RRDAEAAKSFILDMYARVYASCAEPQDGGRKGSRARRFFA--HFTCATDTQSVRSVFKDVRDSVLARYLDEINLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30679-1", "uniprot_id": "GNA15_HUMAN", "id": "P30679-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "-------MARS-LTWRCC-------PWCLTEDEKAAAR-------------VDQE-----------------INRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFS----------------------------------------------------------------------------------------RPESKHHASLVMSQDPYKVTTFE-----------------------KRYAAAMQWLWR-DAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLR-IVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPT--SHLATYFPSFQGP----------------KQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFS--HYTCATDTQNIRKVFKDVRDSVLARYLDEINLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHS4-1", "uniprot_id": "A0A8M2BHS4_DANRE", "id": "A0A8M2BHS4-1", "name": "Guanine nucleotide-binding protein subunit alpha", "aln": "-------MGCWRWCYTTC-------ICCLSEEDKNAIV-------------IHNE-----------------IKRILAEQKKRERREIKVLLLGTGESGKTTFIKQMRIIHGKGFSEEDRRGYIKNVYQNIFTAMRAMTGAMESLRIPYA----------------------------------------------------------------------------------------NPQNEAYGRQFKDVEIRQVTQLD-----------------------RMYVEAIRRLWA-DPGIKACYCRRREYQLLDSTEYYMTNLDRITAPDYIPTAQDVLRVRFPTTGINDYSFSVEKITLR-IVDVGGQKSERRKWIHCFENVTSLIFLASLSEYDQVLEENSKENRMKESLSLFYTTIHSPWFASASIILFLNKMDILEEKIQS--SDLKAYFPEFQGK----------------KRDKNDAKTYISSLYRKEAS--------NRESGMHRGFYM--HFTCATDTNNIRKVFMDVKETILTNELQSIGML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RS61-1", "uniprot_id": "A0A8M1RS61_DANRE", "id": "A0A8M1RS61-1", "name": "", "aln": "-------MGHYYYTCPCI-------VWFLSEEEKNAID-------------INNE-----------------IKRILQEQKKQQRKEIKVLLLGSGESGKTTFLKQMRIIHGQGFSDDERHVFTKLVYQNIFKSMQAMTEAMSELKIPYA----------------------------------------------------------------------------------------NPQSEVYATWFQDQDPHKITKLQ-----------------------RSYVEAIRHLWA-DKGIKSCYSRRREYQLLDSTKYFLSNLDRIAADIYIPTNQDILQVRFPTSGITDHSFNFEKMILR-IVDVGGQRGQRKKWIHCFENVTSLIFVASLSEYDQRLEENNKDNRMLESLSLFYTTIHSKWFAYSSVILFLNKIDILEEKIQF--SNLKSYFPEFKGK----------------PRNGQDAIQFIKELYTHNAY--------SSETKSSKNVYF--HYTCATDTNNIRSVFSDVKDILLLKALQDFEMA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27601-1", "uniprot_id": "GNA13_MOUSE", "id": "P27601-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "MADFLP--SRSVLSVCFP-------GCVLTNGEAEQQR-------------KSKE-----------------IDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWG----------------------------------------------------------------------------------------DNKNQLHGDKLMAFDTRAPMAAQGM---------------VETRVFLQYLPAIRALWE-DSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFK-MVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQV--VSIKDYFLEFEGD----------------PHCLRDVQKFLVECFRG-----------KRRDQQQRPLYH--HFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q7Y5-1", "uniprot_id": "GNA13_RAT", "id": "Q6Q7Y5-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "MADFLP--SRSVLSVCFP-------GCVLTNGEAEQQR-------------KSKE-----------------IDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWG----------------------------------------------------------------------------------------DNKNQVHGDKLMAFDTRAPMAAQGM---------------VETRVFLQYLPAIRALWD-DSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFK-MVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQV--VSIKDYFLEFEGD----------------PHCLRDVQKFLVECFRG-----------KRRDQQQRPLYH--HFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14344-1", "uniprot_id": "GNA13_HUMAN", "id": "Q14344-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "MADFLP--SRSVLSVCFP-------GCLLTSGEAEQQR-------------KSKE-----------------IDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWG----------------------------------------------------------------------------------------DNSNQQHGDKMMSFDTRAPMAAQGM---------------VETRVFLQYLPAIRALWA-DSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFK-MVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFEGD----------------PHCLRDVQKFLVECFRN-----------KRRDQQQKPLYH--HFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27600-1", "uniprot_id": "GNA12_MOUSE", "id": "P27600-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "MSGVVRTLSRCLLPAEAG-ARERRAG-AARDAEREARR-------------RSRD-----------------IDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ----------------------------------------------------------------------------------------HSENEKHGMFLMAFENKAGLP-------------------VEPATFQLYVPALSALWR-DSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFK-MVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKS--VSIKKHFPDFKGD----------------PHRLEDVQRYLVQCFDR-----------KRRNRS-KPLFH--HFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63210-1", "uniprot_id": "GNA12_RAT", "id": "Q63210-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "MSGVVRTLSRCLLPAEAG-ARERRAG-AARDAEREARR-------------RSRD-----------------IDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ----------------------------------------------------------------------------------------HSENEKHGMFLMAFENKAGLP-------------------VEPATFQLYVPALSALWR-DSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFK-MVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKS--VSIKKHFPDFKGD----------------PHRLEDVQRYLVQCFDR-----------KRRNRG-KPLFH--HFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03113-1", "uniprot_id": "GNA12_HUMAN", "id": "Q03113-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARR-------------RSRD-----------------IDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ----------------------------------------------------------------------------------------YSENEKHGMFLMAFENKAGLP-------------------VEPATFQLYVPALSALWR-DSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFK-MVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFRGD----------------PHRLEDVQRYLVQCFDR-----------KRRNRS-KPLFH--HFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * : ::****..:***:*.:**::::* : : . : : ** * * : * *::* . *:: :. . : . :*:* * *.** : * . :: :.*.***:.:*::*:.**:.: .::: * :: : * .*: *: :* . : ..:***** *:: :*: : : .: :: : : : * * :* .:: *: : : * : ", "identical_positions": 52, "similar_positions": 88, "identity": "9.42%" }, { "cls_id": "homologset.agr.SGD:S000001049", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VB31-1", "uniprot_id": "C6A18_DROME", "id": "Q9VB31-1", "name": "Probable cytochrome P450 6a18", "aln": "----------------------------MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPL---RGNMEGYKKTRTVHEIHQEYYNKYR-NSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDD--------PMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVA----EEFMAVMH--EKVSEN--SILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLD--SRHGNLVSGLMRSYPNLARRLGL--CRNTAQIQEFYQRIVKETVTLREKENIKRN-DFMDMLIGLKNQKNMT-------LENG---EVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLE-QHDQK---FTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPG------NPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRP----------------SVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCS-ATPDPLTFDPHSAILLGIKGGIQLKVEAI-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q27593-1", "uniprot_id": "CP6A8_DROME", "id": "Q27593-1", "name": "Cytochrome P450 6a8", "aln": "----------------------------MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLI---RGNMEELQKTKNIHEIFQDHYNKFR-ESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDD--------PISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVA----NEFMTVMH--EKVPKN--SVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVD--KRHGTLLNGFMRSYPKLARKLGM--VRTAPHIQEFYSRIVTETVAVREKEHIKRN-DFMDMLIELKNQKEMT-------LENG---DVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIE-QHDQN---FTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPG------HPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRP----------------SVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCS-KTPNPLVYDPK-SFVLGVKDGIYLKVETV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q27594-1", "uniprot_id": "CP6A9_DROME", "id": "Q27594-1", "name": "Cytochrome P450 6a9", "aln": "----------------------------MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHIL---MGSLTGVQTSRSFSAIWMDYYNKFR-GT-GPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDD--------PLSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVG----HEFIEVFG--QAMEKS--PIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFE--QRHGPIGIAFINSFQNLARRLHM--KITLEEAEHFFLRIVRETVAFREKNNIRRN-DFMDQLIDLKNSPLTK-------SESG---ESVN-LTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIG-KYNGE---ITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPG------HPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERD----------------SVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCE-QTTIPIVYSKK-TFLISSETGIFLKVERV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V774-1", "uniprot_id": "C6A21_DROME", "id": "Q9V774-1", "name": "Probable cytochrome P450 6a21", "aln": "----------------------------MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHIL---MGSMKGVRTARSFNEIWTSYYNKFR-GS-GPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDD--------PLSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVA----NEFTDVFG--QNVAKS--PVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTE--QRLGPVGIGFVNSFPNLARRLHM--KMTAEPIERFFMRIVRETVAFREQNNIRRN-DFMDQLIDLKNKPLMV-------SQSG---ESVN-LTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIE-KCNGE---LNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPG------HPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERD----------------SVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCE-KTTIPMTYNKE-MFLIASNSGIYLKAERV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P82711-1", "uniprot_id": "C6A19_DROME", "id": "P82711-1", "name": "Probable cytochrome P450 6a19", "aln": "-------------------------------MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIP---LGNTGELWRTMPLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDD--------PLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVG----DEMIRVVD--EKISSS-SQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRE--RRHGWLVDLLIFGMPKLAVKLGF--QFLLPSVQKFYMKIVQDTIDYRMKRKVTRN-DFMDTLIDMKQQ-----------YDKG---DKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLE-RYNGK---LEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHS-------NPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRP----------------TCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHP-KTPVPMKYTIN-NLLLGSEGGIHLNITKVVRD--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V773-1", "uniprot_id": "C6A20_DROME", "id": "Q9V773-1", "name": "Probable cytochrome P450 6a20", "aln": "-------------------------------MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIP---YGNTSELMKTVHFADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDD--------PLSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVG----DELIRVFG--ETASAD-SDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITE--RRHGKSMDLLLFGAPELAAKLRM--KATVQEVEDFYMNIIRDTVDYRVKNNVKRH-DFVDMLIEMKLK-----------FDNG---DKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLK-QHNGK---LDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHT-------NPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRP----------------ACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTD-DFLLSSKGGIHLKVTRV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V770-1", "uniprot_id": "C6A17_DROME", "id": "Q9V770-1", "name": "Probable cytochrome P450 6a17", "aln": "--------------------------------MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPL---FGNIKDWPNKRHIAEIFRDYYFKYK-NSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDD--------PLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVG----EEMDKVFR--SKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITE--HRYGNMLDIFLFGFPKLSRRLRL--KLNIQEAEDFYTKIVRETIDYRLRTKEKRN-DFMDSLIEMYKN-----------EQSG---NSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFG-KHNKE---FTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPE-------DPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARP----------------SCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSP-ETQIPMKIVVK-NILISAENGIHLKVEKLAK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V771-1", "uniprot_id": "C6A23_DROME", "id": "Q9V771-1", "name": "Probable cytochrome P450 6a23", "aln": "-------------------------------MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPI---YGNMKDWPKKRHIAMIFRDYYTKYK-RSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDD--------PLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVG----EEMEKIFS--AKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIE--RRYGGLLDFLIFGFPKLSRRLRL--KLNVQDVEDFYTSIVRNTIDYRLRTNEKRH-DFMDSLIEMYEK-----------EQAG---NTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLS-KHNNE---FTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPE-------DPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARP----------------SCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVST-ETQIPMKFVVK-SILLSAENGIHLKVEKLSK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V769-1", "uniprot_id": "C6A22_DROME", "id": "Q9V769-1", "name": "Cytochrome P450 6a22", "aln": "-------------------------------MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFP---VGNMEGFRKNKHFIDIVTPIYEKFK-GNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDD--------PLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVG----EELTQVCG--ELADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSE--RRHCKLVDGFIESFPEVARFLRM--RQIHQDITDFYVGIVRETVKQREEQGIVRS-DFMNLLIEMKQR---------------------GELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALR-LHNGE---FTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKG------DRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRP----------------TAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCP-RTDPKIEFLKS-NILLCPANGIYLKVQQLSQMSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4U9-1", "uniprot_id": "C6A13_DROME", "id": "Q9V4U9-1", "name": "Probable cytochrome P450 6a13", "aln": "-------------------------------MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYF---RGNMSGLGRDLHWTDINLRIYRKFR--GVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDD--------PLTGNLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVG-------EKLTQ--ACRLQV--GEIEAKDLCARFTTDVIGSCAFGLECNSLQDPESQFRRMGRSVTQE--PLHSVLVQAFMFAQPELARKLRF--RLFRPEVSEFFLDTVRQTLDYRRRENIHRN-DLIQLLMELGEEG------------------VKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLK-RNNQK---LTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIP-------NSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARH----------------PFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSE-KTQIPLKFSSR-NFLISTQEGVHLRMEGLERP--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4U7-1", "uniprot_id": "C6A14_DROME", "id": "Q9V4U7-1", "name": "Probable cytochrome P450 6a14", "aln": "-------------------------------MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPI---VGNMRGIVKKYHFRDINQRIYKKFK--GQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDD--------PLTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVK--EAKVEE--GNVEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTR--RRHSTLVQSFIFTNARLARKLRI--KVLPDDLTQFFMSTVKNTVDYRLKNGIKRN-DFIEQMIELRAEDQEA-------AKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGE---LNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIP-------NSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRH----------------PMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSN-RTDVPLIFSKK-SFLLTTNDGIYLKVERV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2J9F6-1", "uniprot_id": "X2J9F6_DROME", "id": "X2J9F6-1", "name": "", "aln": "-------------------------------MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFL---FGHFFRLQS-VHYSELLQETYDAFR--GSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHG---D--------PLTANLFNLQGEEWRNLRTKLSPTFTSGKMKYMFGTVSTVA----QQLGGTFD--ELVGSQ-GAVLELHDLMARYTTDVIGSCAFGTECSSLREPQAEFRQVGRRIFRN--SNRSIRWRIFKMTYLSSLAKLGLPVRILHPDITKFFNRIVRETVELRERENIRRN-DFMDLLLDLRRQ------------ENG------KGLTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIG--KHGK---LTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDYEIPSP---DGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERH----------------PTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPP-GSPTQLKVTKR-NLILLPSDGVRLQVDPVESRLM------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I1-1", "uniprot_id": "CP9B2_DROME", "id": "Q9V4I1-1", "name": "Cytochrome P450 9b2", "aln": "-----------------------------MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPF---VGNMAAAALQKSSFQRQLTEFYERTRQHK--LVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQ-PFITSND-------RLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSK---TLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFS--RGLQFFKFMLSTLVPKLFSLLKL--TIFDSAKVDYFARLVVEAMQYREKHNITRP-DMIQLLMEAK-------------------NESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAP---LTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYT---LTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMV----------------PYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASG--FNFTPRSGFWMHLVPRK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I0-1", "uniprot_id": "CP9B1_DROME", "id": "Q9V4I0-1", "name": "Cytochrome P450 9b1", "aln": "-----------------------------MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPF---LGNMAASALQKASFQKQISEFYNRTRHHK--LVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQ-TLNIPNE-------RLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQP---IAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFS--RGLPFLKFMMCLLAPKVFNFFKL--TIFDSTNVEYFVRLVVDAMQYREKHNITRP-DMIQLLMEAK-------------------KESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAP---LTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYT---LTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLI----------------PYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARG--FNIIPTTGFWMQLVSRK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG82-1", "uniprot_id": "CP9F2_DROME", "id": "Q9VG82-1", "name": "Probable cytochrome P450 9f2", "aln": "------------------------------MLWEFFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLY---FGNMAGMFLRKRAMFDIVCDLYTKGGSKK--FFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDS---RVQEN---ELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTF--TFLQSMKFMLFFALKGLNKILKV--ELFDRKSTQYFVRLVLDAMKYRQEHNIVRP-DMINMLMEARG----------IIQTEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKE---LTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDIT---FDVDG--QKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQ----------------PFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSG--FQLSPKGGFWIKLVQRN----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9L1-1", "uniprot_id": "CP6W1_DROME", "id": "Q9V9L1-1", "name": "Probable cytochrome P450 6w1", "aln": "--------------------------------MLLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPV---VGCTREFLTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHND-------ALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLG---------SGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSL--TLSRGIDFAIIFMIPALASLARV--KLFSRETTKFIRSSVNYVLKERERTGEKRN-DLIDILLALK------------REAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDE--DH---ISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHN-MELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLN----------------MDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTS--PVMASKRDIILRVEKVSGKKDFGQK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRB3-1", "uniprot_id": "CP6V1_DROME", "id": "Q9VRB3-1", "name": "Probable cytochrome P450 6v1", "aln": "----------------------------MVYSTNILLAIVTILTGVFIWSRRTYVYWQRRRVKFVQPTHL---LGNLSRVLRLEESFALQLRRFYFDERFRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSD-------KMGALSLFLAKQPEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRP--NVRRIIDLFVIFYLPKLVPLLRP--KLFTEPHAEFLRRVIQLVIEERERGGDLRN-DLIEMLLTLK------------KEADLQQDKSHFTHHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGR---LTYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAE-CYTRRGMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKALQA----------------PMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKF--ALLASEQRIYLKVDCL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V675-1", "uniprot_id": "CP6G2_DROME", "id": "Q9V675-1", "name": "Probable cytochrome P450 6g2", "aln": "------------------------------MELVLLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWI---VGNLMGLLNMRMSPAEFISQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGD-------PLGSQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPL---HNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEF--NLLRAAEFTLVFFLPHLVPFVRF--KVVPAEATRFLRKTINYVMSEREKSGQKRN-DLIDILIEFRRS---------TQLAKASGIKDQFVFEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVES-GGQ---VTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGR---DYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHT----------------PYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKA--IITQAKGGIHLRLVRDALGV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V674-1", "uniprot_id": "CP6G1_DROME", "id": "Q9V674-1", "name": "Cytochrome P450 6g1", "aln": "----------------------------MVLTEVLFVVVAALVAL-YTWFQRNHSYWQRKGIPYIPPTPI---IGNTKVVFKMENSFGMHLSEIYNDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGD-------PLGYNNLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGE---KNS--GSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTF--TVARAKDFFVAFFLPKLVSLMRI--QFFTADFSHFMRSTIGHVMEERERSGLLRN-DLIDVLVSLR------------KEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEG-GGS---LSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYD-YTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIV----------------AMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKG--FVLQADGGIHLEIVNDRLYDQSAPSLQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCW1-1", "uniprot_id": "CP6D4_DROME", "id": "Q9VCW1-1", "name": "Probable cytochrome P450 6d4", "aln": "-------------------------------MFSLILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIP--FGCLDSVWRQEKSMGLAIYDVYVK---SKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERD--------PLSANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELP------EEGFKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVS-LARAN-NRFNAMFGMMIFLVPSIAQFLFR--IGFKNPVGLAMLQIVKETVEYREKHGIVRK-DLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGK----ITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYT-------VPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFSEESR-NYN----------------PTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEV-MSRSEIEFE-NSG--IALIPKHGVRVRLSKRVPKLS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W223-1", "uniprot_id": "CP6D2_DROME", "id": "Q9W223-1", "name": "Probable cytochrome P450 6d2", "aln": "--------------------------------MWTILLTILIAGLLYRYVKRHYTHWQRLGVD-EEPAKIP--FGVMDTVMKQERSLGMALADIYAR---HEGKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKD--------PLSANLFNLRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALD------QS--DEVEIKDVMTTYAVDIIGSVIFGLEIDSFRNPKNEFREISSSTSRDE-SLLLKIHNMSMFICPPIAKLMNR--LGYESRILTSLRDMMKRTIEFREEHNVVRK-DMLQLLIRLRNTGKIGEDDDQVWDMETAQE-QLKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYP-------VPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNNM-NYD----------------QAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQ-SPRKEVEFRFDAA--PVLVTKEPLKLRLTKRK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFP1-1", "uniprot_id": "CP6D5_DROME", "id": "Q9VFP1-1", "name": "Probable cytochrome P450 6d5", "aln": "--------------------------------MIGIYLLIAAVTLLYVYLKWTFSYWDRKGFP-STGVSIP--FGALESVTKGKRSFGMAIYDMYKS---TKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKND--------PMSASLFQMEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLP------ANGAKELELKKLMATYAIDIIATTIFGLDVDSFADPNNEFQIISKKVNRN--NIEDIIRGTSSFLYPGLEKFFVK--IGWKQEATERMRELSNRTVDLREQNNIVRK-DLLQLLLQLRNQGKIN-TDDNIWSAESTKN-GVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGK----LTYDAISDMKYLEACILETARKYPALPLLNRICTKDYP-------VPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGK-DYT----------------QAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFG-VYG--IPLMPKSGVPVRLSLKK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V979-1", "uniprot_id": "CP6U1_DROME", "id": "Q9V979-1", "name": "Probable cytochrome P450 6u1", "aln": "----------------------------MDLMHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFL---WGNIKGVVSGKRHAQDALQDIYTAY-KGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGE--------PLSHNLLQLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQIS----SRIQRDLG------EKSLQTINISELVGAYNTDVMASMAFGLVG----QDNVEFAKWTRNYWAD----FRMWQAYLALEFPLIARLLQY--KSYAEPATAYFQKVALSQLQLHRRRDRQPL-QTFLQLYSN----------------------AEKPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQV----TPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVP-------GSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRP----------------AAAFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRR--LLLMPKSDIKLSVERVDKL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K0C4-1", "uniprot_id": "CP51A_MOUSE", "id": "Q8K0C4-1", "name": "Lanosterol 14-alpha demethylase", "aln": "------MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGA--KSPPH--IYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTP-------VFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWG------------ESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFT----------HAAWLLPAWLPLPSFR---RRDRAHREIKNIFYKAIQKRRLSKEPAE-DILQTLLD-STYKD------------------GRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCG-EDLPP---LTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVA---------GYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPAS----------------GEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLING-YFPTVNYTTM---IHTPENP-VIRYKRRSK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64654-1", "uniprot_id": "CP51A_RAT", "id": "Q64654-1", "name": "Lanosterol 14-alpha demethylase", "aln": "------MVLLGLLQSGGSVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGA--KSPPY--IYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTP-------VFGKGVAYDVPNAVFLEQKKILKSGLNIAHFKQYVSIIEKEAKEYFKSWG------------ESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFS----------HAAWLLPGWLPLPSFR---RRDRAHREIKNIFYKAIQKRRLSKEPAE-DILQTLLD-STYKD------------------GRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCG-EDLPP---LTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVA---------GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPAS----------------GEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLING-YFPSVNYTTM---IHTPENP-VIRYKRRSK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16850-1", "uniprot_id": "CP51A_HUMAN", "id": "Q16850-1", "name": "Lanosterol 14-alpha demethylase", "aln": "MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGV--KSPPY--IFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTP-------VFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWG------------ESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFS----------HAAWLLPGWLPLPSFR---RRDRAHREIKDIFYKAIQKRRQSQEKID-DILQTLLD-ATYKD------------------GRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCG-ENLPP---LTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA---------GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPAS----------------GEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDG-YFPTVNYTTM---IHTPENP-VIRYKRRSK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPY5-1", "uniprot_id": "CYP51_DANRE", "id": "Q1JPY5-1", "name": "Lanosterol 14-alpha demethylase", "aln": "---------MTILEVGSQLIESAVLQMS---LTSVLLTASVFTLTLGYFSKLLFTQHSSEHT----KYPPH--IPSSLPFLGQAVAFGRSPIEFLEKAYEQYGPVVSFTMVGKTFTYLLGSDAAALMFNSKNEDLNAEDVYARLTTP-------VFGKGVAYDVPNPLFLEQKKMLKTGLNIAQFKQHVEIIEEETKDYFRRWG------------ESGERNLFDALSELIILTASRCLHGCEIRSLLDERVAQLYADLDGGFT----------HAAWLLPGWLPLPSFR---RRDRAHLEIKKIFYNVIKKRREDTEKHD-DILQTLID-ATYKD------------------GRPLSDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQKSVCG-EELPP---LHYDQLKDLSLLDRCLKETLRLRPPIMTMMRMAKTPQKVG---------EYTIPPGHQVCVSPTVNHRLQDTWAERLDFDPDRYLHDNPAA----------------GEKFAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDFELVDG-HFPPVNYTTM---IHTPHNP-IIRYTRRNTQPQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10614-1", "uniprot_id": "CP51_YEAST", "id": "P10614-1", "name": "Lanosterol 14-alpha demethylase CYP51", "aln": "------------MSATKSIVGEALEYVNIG-LSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPL--VFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTP-------VFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRL-----NERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFT----------PINFVFP-NLPLEHYR---KRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKD------------------GVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLD-GGKKE---LTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPN-------TSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSM---VTLPTGPAKIIWEKRNPEQKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V776-1", "uniprot_id": "CP317_DROME", "id": "Q9V776-1", "name": "Probable cytochrome P450 317a1", "aln": "---------------------------MWIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSD--------PLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMS------QPHSTVHIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNS-HKHGYLMNLMMIRFPNFCRMLRMR--RTPKQAEEYFIKLLTSIVEQRETSGKPQK-DYLQLLIDVKALEFIT--------HQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHI----THEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVP------DHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQE----------------QGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTRKPLINLEDGIA--LTLMPLGVIEPGNEERAV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVN6-1", "uniprot_id": "CP312_DROME", "id": "Q9VVN6-1", "name": "Probable cytochrome P450 312a1", "aln": "------------------------------MFWLGFGLLLLALSLYLLYVFERQSRIDRLTHKWPAPPALP----FIGHLHILAKLVGPHPLRRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFEN--------WLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAE--------SGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKRE--QELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLD-----TLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEP---ISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIN---------DFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIE----------------ATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLG---ERQVKLKLNFVITLHTVEPYLCRAKNLD----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . * : : : . .. : . : . : : * * * :. : : : .: : * * : *:. . . .: ", "identical_positions": 7, "similar_positions": 34, "identity": "1.15%" }, { "cls_id": "homologset.agr.SGD:S000001050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07895-1", "uniprot_id": "SODM_RAT", "id": "P07895-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLCRAACSAGRRLG--PAASTAGSRHKHSLPDLPYDYGALEPHINAQIMQLHHSKHHATYVNNLNVTEEKYHEA---LAK----GDVTTQVALQPALKFNGGGHINHSIFWTNLSP---KGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQG-RLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVSQRYIVCKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09671-1", "uniprot_id": "SODM_MOUSE", "id": "P09671-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLCRAACSTGRRLG--PVAGAAGSRHKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNATEEKYHEA---LAK----GDVTTQVALQPALKFNGGGHINHTIFWTNLSP---KGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQG-RLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYTACKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04179-1", "uniprot_id": "SODM_HUMAN", "id": "P04179-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLSRAVCGTSRQLA--PVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEA---LAK----GDVTAQIALQPALKFNGGGHINHSIFWTNLSP---NGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERG-HLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00637-1", "uniprot_id": "SODM_DROME", "id": "Q00637-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "------MFVARKIS--QTAS-LAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEA---KSK----SDTTKLIQLAPALRFNGGGHINHTIFWQNLSP---NK-TQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSG-KLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00447-1", "uniprot_id": "SODM_YEAST", "id": "P00447-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTVTGP--LVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASRRFDAGKI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . * * :**.* :*:.**** * :* :**: *** :***.:*.: :: .* :* .:. : : ::*:***. ** :** **:* *.. * :**. :: *:::: : .: ..******.:: * . * :*::. ***.: .. *:**..**.*********:* :..*.:***:: **.: : *: * ", "identical_positions": 74, "similar_positions": 75, "identity": "31.09%" }, { "cls_id": "homologset.agr.SGD:S000001051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96CU9-1", "uniprot_id": "FXRD1_HUMAN", "id": "Q96CU9-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1", "aln": "MIRRVLPHGMGRGLLTRRPGTRRGGFSLD---WDGKVSEIKKKIKSILPGRSCDLLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQAS-TGLSVGGICQQFSLPENIQLSLFSASFLR------------NINEYLAVVDAPPLDLRFNPSGYLLLASEKDAAAMESNVKVQRQEGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWF-----DPWCLLQGLRRKVQS---------LGVLFCQGEVTRFVSSSQRMLTTDDKAVVLKRIHEVHVKMDRS----LEYQPVECAIVINAAGAWSAQIAALAGVGE--GPPGTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTSG---AYFRREGLGSN---YLGGRSPTEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYY-DYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGRFQTIDLSPFLFTRFYLGEKIQENNII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZEH2-1", "uniprot_id": "D3ZEH2_RAT", "id": "D3ZEH2-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1", "aln": "MFRKVLRLGLCPGLPTRGLRTRTGGFTLD---WDTKVSDFKKKIESILPGKQCEMVYDTSHLPPEQSDVVIIGGGILGLSVAFWLKKLESRRGAMQVLVVEQDHTYSRASSTGPSVGGIWQQFSVPENVQLSLFSINFLR------------NINEYLAVVDAPPVELRFNPSGCLLLASEKDAATLESNVRMQRQEGAKVCLMSPEQMQNKFPWMNAEGVALASYGLENEGWF-----DAWSLLQGLRRKVQS---------MGVFFCQGEVTRFITSSNQMETPTGEQVVLRRINNVHVKMDKS----LEYQPVECAVVVNAAGAWSGQIAELAGIGK--GLPGTLQGTKLPVEPRKRYVHLWHCPQGPGLETPLVADISG---VYFRREGLGSN---YLGGCSPTEEEEPDPTNLEVDHDFFQNKVWPHLVQRVPSFKTLKVQSAWAGYY-DYNTFDQNGVVGPHPLVVNMYFATGFSGRGLQHAPGIGRAVAEMILEGHFKTIDMSPFLFTRFYLGEKLQEHNIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38758-1", "uniprot_id": "TDA3_YEAST", "id": "P38758-1", "name": "Putative oxidoreductase TDA3", "aln": "-MGEDFMHPPFQTYPSKNSEGKKHIVIVGGGIIGCCTAYYLTQHPSFSPSTHHITIIESRRIAGGASGKAGGLLASWAFPHQIVPLSFQLHQELSDEYDGENNWDYRRLTTVSLEADVREEVIENYERLSKKAYNLNVPPPKKRPGYISNKFNIGDSNSSLSSSGSSLKNDSASNEEEGSDIHVSSSVPSLHSLTNERMRSHTNSASDLDSVSPVEQLRETNIHNPLPADLDWIRRELVNDWSSLGGTDTTAQLHPYKFTHFILSKAMETGAVDLLLGKVVGLKCDEMDCVHSLKYLPSVVKNRRNSRGHAENPDIKLGTIFNDENAKPIEINDIQQIVLSMGPWTSKILKDCPISGLRAHSVTIKPSEKTVSPYAILAELKVNDREFFSPEMYARKDEVYVCGEGDTLVNIPESSDDVEVVSEKCDELYHYVSKLSPTLSKGHLLRKQACFLPVLNVPTSSGPLIGETNVKDLYIASGHSCWGINNAPATGKLMAEILLDGEATSAEIS-SLDPKLYFDATILS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :: : . :. . .: .: *: *. : :: ::. *. . . .:. .:: :: *.: * : : .. ... : :. *.:. . :. .. **.: : :.:. .*: :.:. .*: ..:: ..:: :* : *..:: . * : . . : . : .*: : *. * * ..* :. : * * :: . : . * : ** :. * :: . :.* .* . :* : : * : .. *:. : : : .: . .::*: . :* * . : *: * . * : *:.:: . :::: :: *::.. :: * : *. ..* : .. * ::*:*:*.* *:::**. *: :**::*.*. : ::* * .::*:. .: . ", "identical_positions": 56, "similar_positions": 188, "identity": "10.59%" }, { "cls_id": "homologset.agr.SGD:S000001052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61353-1", "uniprot_id": "RL27_HUMAN", "id": "P61353-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61354-1", "uniprot_id": "RL27_RAT", "id": "P61354-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61358-1", "uniprot_id": "RL27_MOUSE", "id": "P61358-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTK5-1", "uniprot_id": "D3ZTK5_RAT", "id": "D3ZTK5-1", "name": "60S ribosomal protein L27", "aln": "MGKFMKPGKVVLVLAGRYSGYKAVIVKNIDDGTSDRPYSHVLVAGIDCYPRKVTAAMG-KKMAKRSKIKSFVKVYNYSHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7P0-1", "uniprot_id": "M0R7P0_RAT", "id": "M0R7P0-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKLMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKITKQSKIKSFVKVYNYNHFMPTRYSV-DIPLDKTVVNKDVFRDSALKRKARREVKVKFEERYKTGKNKRFFQKFRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZV82-1", "uniprot_id": "RL27_DANRE", "id": "Q7ZV82-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVMVLAGRYAGRKAVIVKNIDDGTADRPYSHALVAGIDRYPRKVTATMGKKKIAKRSKIKAFVKVFNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBN5-1", "uniprot_id": "Q9VBN5_DROME", "id": "Q9VBN5-1", "name": "60S ribosomal protein L27", "aln": "MRKIMKQGKIVIVLSGRYAGRKAIIVKTHDDGTPEKPFGHALVAGIDRYPRKVTKKMGKNKLKKKSKVKPFLKSLNYNHLMPTRYTAHDISFEKLSP-KD-LKDPVKRKTHRFQTRVKFESVYKEGKNKWFFQKLRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C2H6-1", "uniprot_id": "RL27A_YEAST", "id": "P0C2H6-1", "name": "Large ribosomal subunit protein eL27A", "aln": "MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPLKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTL-DVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::* **:.:*: ***:* *.:*** *:*: .:*:.*.*****: ** *** * :*: *::*:*.*:* **.*::****: *: * .: :.:. :. : .: **. :: ***: **.*:**", "identical_positions": 54, "similar_positions": 46, "identity": "39.42%" }, { "cls_id": "homologset.agr.SGD:S000001053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM09-1", "uniprot_id": "D3ZM09_RAT", "id": "D3ZM09-1", "name": "Serine--tRNA ligase, mitochondrial", "aln": "MAASMARLLWPFLARQGLRFRGRCVCNQNPRRSFATEKRVRNLLYEHAREGYSELPYLDMESVCACPEKAARSLELRKGELRPADLPAIISTWQELRQLREQIQSLEAEKEAVAEAVRALLAKQDSNQVQKDPQYQGLRTRGREIRKQLTPLYPRETQLEEEFYQQALRLPNQTHPDTPVGDESQARVLRVVGDKPAFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTLSKLVSRGFTPMTVPDLLRGAVFEGCGMTPN--ANPSQIYNIDPSRFEDLNLAGTAEVGLAGYFMDHAVASR--DLPVRMVCASTCYRAETDT-GKEPWGLYRVHHFAKVEMFGVTGPGLEQSSQLLEEFLSLQVEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRYGEVTSASNCTDFQSRRLYIMF-ETETGELQFAHTVNATACAVPRVLIALLE-SNQQKDGSVLVPAALQPYLG-TDRITAPTHVPLQYIGPNQPQKPRLPGQSAAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJL8-1", "uniprot_id": "SYSM_MOUSE", "id": "Q9JJL8-1", "name": "Serine--tRNA ligase, mitochondrial", "aln": "MAASMARLWWPFLARQGLRSRGRCVCSQNPRRSFATEKRVRNLLYEHAREGYSELPYLDMESVCACPEKAARSLELRKGELRPADLPAIISTWQELRQLREQIRSLEAEKEAVAEAVRALLANQDSDQVQKDPQYQGLRARGREIRKQLTPLYPQETQLEEQLYQQALRLPNQTHPDTPVGDESQARVVRVVGEKPAFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTLSKLVSRGFTPMTVPDLLRGAVFEGCGMTPN--ANPSQIYNIDPSRFEDLNLAGTAEVGLAGYFMDHSVAFR--DLPVRMVCASTCYRAETDT-GKEPWGLYRVHHFTKVEMFGVTGPGLEQSSQLLDEFLSLQVEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRYGEVTSASNCTDFQSRRLYIMF-ETETGELQFAHTVNATACAVPRVLIALLE-SNQQKDGSVLVPAALQPYLG-TDRITAPTHVPLQYIGPNQPQKPRLPGQSATR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP81-1", "uniprot_id": "SYSM_HUMAN", "id": "Q9NP81-1", "name": "Serine--tRNA ligase, mitochondrial", "aln": "MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDIERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPN--ANPSQIYNIDPARFKDLNLAGTAEVGLAGYFMDHTVAFR--DLPVRMVCSSTCYRAETNT-GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMF-QTEAGELQFAHTVNATACAVPRLLIALLE-SNQQKDGSVLVPPALQSYLG-TDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF85-1", "uniprot_id": "Q9VF85_DROME", "id": "Q9VF85-1", "name": "serine--tRNA ligase", "aln": "-----------------------------------------------------------------------------------MKLPTNSQLWRPLLLLRRQRS--HDAKAVEAPIHRPVPTSAQLDELERNVVVRHHKNNVPLIRSLIQELDAGDQHKLRQLQAELEQLPNATHPRLRDYGEEPRELAQYVHRQLTPQSRLKEFSELARALNLYRMDHLGNYTGHKSYYLTGQLATLEQAIIQYALQAVTEHGFKLISVPDILPKEVIESCGMRTE--GERTQVYKLDTG----ECLSGTSEMALAGFFANKLLSED--QLPLKVTAVSRCYRAETSG-LQEEKGIYRVHQFNKVEMFAICTE--EQSEAELEEFKNIEVDLFRRLGLNFRLLDMPPCELGAPAYQKYDIEAWMPGRQMWGEISSCSNCTDYQARRLGIRYRRSADGQILHAHTINGTATAIPRLLIALLE-SYQKEDG-IEIPAVLRPFMDNQELITRNKRIPETKLVKFIKA-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38705-1", "uniprot_id": "SYSM_YEAST", "id": "P38705-1", "name": "Serine--tRNA ligase, mitochondrial", "aln": "-------------------------------------MIIRRLFSISNRSFFLKKPQFDVKKIIEMIPQYQTSIQNR-------ELIEADSIIRSLQLLGERYQNIKEIDKVIADIQIQRKS-IEAQIKKDKTKITEYSAALKALKEQYNDQNSKSSELKKKILETCKSLPNTLDPTVPLDAPQIEQWINPLKTHKTS--EAQAHVDIMLKKNMLDLQTASNVTGMSWYYLLNDGARLEQALVAYALKKANENGFSSCVPPSITKKELIDACGFNPRDMNNERQIYALQDTN---LGLVATAEIPLAGLGANKVLELNSGECSKKLVGVSRCYRAEAGARGKDTKGLYRVHEFTKVELFCWSKP--ETSAKVLEEIKQFQISVVEELGIPAKVLNMPSNDLGNPAFKKYDIEAWMPGRGKFGEISSASNCTDFQSRRLNTKYRDDNTGKLEYVHTLNGTAMAIPRVIVALVENFYDPSTGKISVPECLREFMNGQRYI----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : * * .: . . . : : : : . ::. . . . .:: *** .* . . . : : . . : . :: :: . .: :* *** . * *::.:: :::. .**. *.: :::.**: .. : *:* :: * .*:*: *** :: : : . ::. * *****:. :: *:****.* ***:* * * *:*: .:::.:. .**: ::*:**. :** **::*:********* :**::*.*****:*:*** : *:: ..**:*.** *:**:::**:* : . * : :* *: ::. * ", "identical_positions": 93, "similar_positions": 128, "identity": "17.68%" }, { "cls_id": "homologset.agr.SGD:S000001054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ78-1", "uniprot_id": "VPS29_RAT", "id": "B2RZ78-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDESLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ88-1", "uniprot_id": "VPS29_MOUSE", "id": "Q9QZ88-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBQ0-1", "uniprot_id": "VPS29_HUMAN", "id": "Q9UBQ0-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV68-1", "uniprot_id": "VPS29_DANRE", "id": "Q7ZV68-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNTLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQLDVDILISGHTHKFEAFENENKFYINPGSATGAYS-----------------------------------------------------------ALESNITP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPX5-1", "uniprot_id": "Q9VPX5_DROME", "id": "Q9VPX5-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCSSLPAKFKKLL-VPGRIHHILATGNICTKESYDYLK---SLANDVHIVRGDFDENLTYPEQK-----------------VVTVGQFRIGLCHGHQVVPRGDPEALALIQRQLDVDILITGHTYKFEAYEHGNKFYINPGSATGAFN-----------------------------------------------------------PLDTNVVP----------------------SFVLMDIQSTTVVTYVYQLIGDEVKVERIEYKKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38759-1", "uniprot_id": "VPS29_YEAST", "id": "P38759-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLLLALSDAHIPDRATDLPVKFKKLLSVPDKISQVALLGN--STKSYDFLKFVNQISNNITIVRGEFDNGHLPSTKKDKASDNSRPMEEIPMNSIIRQGALKIGCCSGYTVVPKNDPLSLLALARQLDVDILLWGGTHNVEAYTLEGKFFVNPGSCTGAFNTDWPIVFDVEDSDEAVTSEVDKPTKENQSEDDDAKGGSTGKEQPGSYTPKEGTAGERENENESNVKPENQFKEDEVDMSDSDINGSNSPSFCLLDIQGNTCTLYIYLYVNGEVKVDKVVYEKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.*.* ***.*.. **.****** **.:* :: ** :.:***:** ::.:: ****:**:. . :* :: * ::** *: *:* .* :* : **:*****: * *::.**: .**::****.***:. ::*: * ** *:***..* . *:* :..:***::: *:* ", "identical_positions": 78, "similar_positions": 62, "identity": "27.46%" }, { "cls_id": "homologset.agr.SGD:S000001055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8K3-1", "uniprot_id": "NAA11_RAT", "id": "Q4V8K3-1", "name": "N-alpha-acetyltransferase 11", "aln": "----------------------------------------------------------------------------------------------MNIR------NARP-------EDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DEDG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLAQMADELRRQLVLK-KSRYVVLGSEENQE---AQDSTLPDAEEACQP-ENPAGKGSEACQPENPAGKGSEACQPENPAGKDTGSHSTDVQDSSEYLDSTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX61-1", "uniprot_id": "NAA11_MOUSE", "id": "Q3UX61-1", "name": "N-alpha-acetyltransferase 11", "aln": "----------------------------------------------------------------------------------------------MNIR------NARP-------DDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DEDG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFGAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLSQMTDELRRQLVLK-KNRYVVLGSEE------TQGGTLPDAGEACLP-KNPTSKDS-----------GS--------------SDSTDVQDSSEDLDSIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSU3-1", "uniprot_id": "NAA11_HUMAN", "id": "Q9BSU3-1", "name": "N-alpha-acetyltransferase 11", "aln": "----------------------------------------------------------------------------------------------MNIR------NAQP-------DDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAE------------DEDG--------------------------KIVGYVLAKMEE--EPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLSQMADELRRQMDLK-KGGYVVLGSRENQE---TQGSTLSDSEEACQQ-KNPATEES-----------GSDSKEPKES------VESTNVQDSSESSDSTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QY36-1", "uniprot_id": "NAA10_MOUSE", "id": "Q9QY36-1", "name": "N-alpha-acetyltransferase 10", "aln": "----------------------------------------------------------------------------------------------MNIR------NARP-------EDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DENG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGKHMVLAALENKAE--NKGNVLLSSGEACREEKGLAAEDS-----------GGDSKDLSEVS---ETTESTDVKDSSEASDSAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41227-1", "uniprot_id": "NAA10_HUMAN", "id": "P41227-1", "name": "N-alpha-acetyltransferase 10", "aln": "----------------------------------------------------------------------------------------------MNIR------NARP-------EDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DENG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVE--SKGNSPPSSGEACREEKGLAAEDS-----------GGDSKDLSEVS---ETTESTDVKDSSEASDSAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT75-1", "uniprot_id": "Q9VT75_DROME", "id": "Q9VT75-1", "name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "aln": "----------------------------------------------------------------------------------------------MNIR------CAKP-------EDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAV------------DDKG--------------------------AIVGYVLAKMEEP-EPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYADGEDAYAMRRDLSEFADE--------DQAKAAKQSGEE--------------EEKAVHRSGGHGHSHN---------HSGHDG------------HCC--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6A9B2-1", "uniprot_id": "A0A8I6A9B2_RAT", "id": "A0A8I6A9B2-1", "name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "aln": "----------------------------------------------------------------------------------------------MGSSPGTGAFCTPPRNPACVPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DENG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADEPA-----PGPGSSCLLSGDLGPVSFHPLPSGLPAAAEAAPGAEGKGQAHG---------AVGHGE------------QGGEQRQRASELRRGLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K7P4-1", "uniprot_id": "A0A0G2K7P4_RAT", "id": "A0A0G2K7P4-1", "name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "aln": "MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKIFLILCESCLDIPAVLKQTVLVSLVLCGILSDSRGLTGLPAASMNIR------RARP-------DDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAE------------DEDG--------------------------KIVGYVLAKMEE--DPDDVP-HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLSQMADELRRQLVLK-KGRYVVLGSKEN------QGSTLPGSEEACQQ-ENLAVGDS-----------GSDG------------KDSTDVQDSLQTLGSAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07347-1", "uniprot_id": "ARD1_YEAST", "id": "P07347-1", "name": "N-terminal acetyltransferase A complex catalytic subunit ARD1", "aln": "--------------------------------------------------------------------------------------------MPINIR------RATI-------NDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDSDEQDENDKLELTLDGTNDGRTIKLDPTYLAPGEKLVGYVLVKMNDDPDQQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQIS-------NFTHRRLKENEE---------KLEDDLESDLLEDIIKQGVN-------------------------------DIIV---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P83877-1", "uniprot_id": "TXN4A_MOUSE", "id": "P83877-1", "name": "Thioredoxin-like protein 4A", "aln": "----------------------------------------------------------------------------------------------MS--------YMLP--------HLHNGWQVDQAILSEEDRVVVIRFG-HDWDPTCMKMD------------------------------------------EVLYSIAEKVKN----------FAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: : : *.*: : : * . :: : *::: : * :. :* . : :.* . :.*: : . ..: . .*.. . : ", "identical_positions": 9, "similar_positions": 40, "identity": "2.26%" }, { "cls_id": "homologset.agr.SGD:S000001058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNA1-1", "uniprot_id": "SH3Y1_RAT", "id": "B0BNA1-1", "name": "SH3 domain-containing YSC84-like protein 1", "aln": "--MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSS--AAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNS-------------------------------------------------------------------FTEKYETEGQ-------------------RINLKKVAREQRK--AKELPPKP--------------SSRPQPSRPPVQLNAGSQSNRNEYKLY-----PELSSYHEKTGSLSQPIEVT-----------------ALYSFEGQQPGDLNFQAGDRIIVISKTDSNFDWWEGKLRGQTGIFPANYVTMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08641-1", "uniprot_id": "SH3Y1_MOUSE", "id": "O08641-1", "name": "SH3 domain-containing YSC84-like protein 1", "aln": "--MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSS--AAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNS-------------------------------------------------------------------FTEKYETEGQ-------------------RINLKKVAREQRK--AKELPPKP--------------SSRPQPAHPPVQLNAGSQGNRNEYKLY-----PELSSYHEKTGNLNQPIEVT-----------------ALYSFEGQQPGDLNFQAGDRIIVISKTDSNFDWWEGKLRGQTGIFPANYVTMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HL8-1", "uniprot_id": "SH3Y1_HUMAN", "id": "Q96HL8-1", "name": "SH3 domain-containing YSC84-like protein 1", "aln": "--MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVALRSS--AAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDS-------------------------------------------------------------------FTEKYENEGQ-------------------RINARKAAREQRKSSAKELPPKP--------------LSRPQQSSAPVQLNSGSQSNRNEYKLY-----PGLSSYHERVGNLNQPIEVT-----------------ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32793-1", "uniprot_id": "YSC84_YEAST", "id": "P32793-1", "name": "Protein YSC84", "aln": "MGINNPIPRSLKSETKKAAKVLRSFVKPNQVFGADQVIPPYVLKRAKGLAIITVLKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGVELTDFVFILNSEEAVRSFSEFGTITLGGNVSVSAGPLGRSAEAAASASTGGVSAVFAYSKSKGLFAGVSVEGSAILERREANRKFYGDNCTSKMILSGRVKVPPAADPLLRILESRAFNFTRHDHDDNASGDDFYDDGQYSDNTSHYYDDIPDSFDSTDESSTRPNTRSSRRRGMSLGSRSRYDDDYDDDGYGRGRGYGDFDSEDEDYDYGRSPNRNSSRNRGPQIDRGTKPRANTRWEDDLYDRDTEYSRPNHSGRDYDNTRGNRRGYGRERGYSLGHGPTHPSNMSNVDDLSHKMSKTGLGNESTATNSATPTAVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVRVS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***** .****:*****:**.*.: .. *.*::**.:*: :*****:::*:*****.:.*.***:::*** **.*******.:** *.* :*:*::*:*:*** :.**.:*:: *.:*****.:*:.*****. *. .: :. :***:*.**:*****:*:***.::**:*:***** :: : ** * . *. *: * .**:* : :.*: :* * :: :*:: : *:. ***: : : . *.: . .. : * * .* .....*.: :. * ***.* *:***** *: ** * ::.*:**: *** *: .*: ******** :.", "identical_positions": 152, "similar_positions": 120, "identity": "32.48%" }, { "cls_id": "homologset.agr.SGD:S000001060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04424-1", "uniprot_id": "ARLY_HUMAN", "id": "P04424-1", "name": "Argininosuccinate lyase", "aln": "---MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIG-ATAGKLHTGRSRNDQVVTDLRLWMRQTCS-TLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVA-LNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YI0-1", "uniprot_id": "ARLY_MOUSE", "id": "Q91YI0-1", "name": "Argininosuccinate lyase", "aln": "---MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIG-EAAGKLHTGRSRNDQVVTDLRLWMRQTCS-KLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVA-LNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20673-1", "uniprot_id": "ARLY_RAT", "id": "P20673-1", "name": "Argininosuccinate lyase", "aln": "---MASESGKLWGGRFAGSVDPTMDKFNSSIAYDRHLWNVDLQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGIFKLYPNDEDIHTANERRLKELIG-EAAGKLHTGRSRNDQVVTDLRLWMRQTYS-KLSTFLKVLIEAMVDRAEAECEVLFPGYTHLQRAQPIRWSHWILSHAVALTRDLERLKEVQKRINVLPLGSGAIAGNPLGVDREFLCAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFNFVQLSDAYSTGSSLMPQKKNPDSLELIRSKARRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMTAVLQVATGVISTLQIHRENMAQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVVVAEMKGVA-LNQLSLQELQTVSPLFSSDVNLVWDYSHSVEQYTALGGTAQSSVEWQISQVRALLQM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04076-1", "uniprot_id": "ARLY_YEAST", "id": "P04076-1", "name": "Argininosuccinate lyase", "aln": "---MSDGTQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTAGLQKLGLLTETELAKIHEGLAEIKKEWDADKFVRHPNDEDIHTANERRLGELIGRDIAGKVHTGRSRNDQVVTDLRIYCRDIVNDTLFPALKGLVEVLIKRAEGEIDVLMPGYTHLQRAQPIRWSHWLSSYATYFTEDYKRLGQILHRLNQSPLGAGALAGHPYGIDREFLAEGLGFNSVIGNSLVAVSDRDFIVELMFWGTLFMNHISRFAEDLIIYCTAEFGFIQLSDAYSTGSSLMPQKKNADSLELLRGKSGRVFGDLTGFLMSLKGIPSTYDKDMQEDKEPLFDCLTTVEHSMLIATGVISTLTVNKEKMEAALTMDMLATDLADYLVRKGVPFRETHHISGECVATAERLGLSGIDKLTLEQYQKIDSRFGQDLFETFNFEQSVERRDATGGTAKSAVLKQLDNLKSQLN------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VLG9-1", "uniprot_id": "Q9VLG9_DROME", "id": "Q9VLG9-1", "name": "", "aln": "MTQIPESCYKMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKNLELLRFDWIEGTVKILPGDEDVHTVNERLLVEITG-ELGQRLHTGRSRNDQVVTDMKLWLRKAIR-ETLGRLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPLGSGALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAALSTDMLATDWAYYLVKKGVPFRQAHHIIGRVVSEAEKRGVD-ITDLPLGDLQKFSPLFGSDIVAVADYSNNVQQYNAIGGTASSSIVEQLRLLKKCARDLAKQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *:*****. . :. * *:.** ::: *::.:*.*: .*.: **:..:* :: ..* : :* . . ..***:**.*** * *: * . ::*************:::: *. * :: . :** . **:**********.:::***: *:* : .* :** :: .* * ***:**:**:* *:** * *.*..: **: *..:***:.:::: :: *:**:*****:* * **.*::*:*.:*:********:*.*****:*. : : . :*::*::** ****:**:* **: *: .: : :: **:.*: :::*.* **: ****** * ***:**:***::*. *. * ** *: : *.* : *.... *. *: . :: :.*:: * **** *:: *: :: . ", "identical_positions": 175, "similar_positions": 153, "identity": "37.08%" }, { "cls_id": "homologset.agr.SGD:S000001061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LPV0-1", "uniprot_id": "F1LPV0_RAT", "id": "F1LPV0-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MSSEVIR---------GTADMVLAELYVSDREGNDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWDVISKSQMKNIKK---MWHREQMKSDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLSRLEDLVCDVVDRVLKSPVA-SIVYDLNPNFKAPKRPFRRMNYSDAIEWLREHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP47-1", "uniprot_id": "SYNC_MOUSE", "id": "Q8BP47-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MSSEVIR---------GTAEMVLAELYVSDREGNDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWDVISKSQMKNIKK---MWHREQMKNDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVA-SIVYELNPNFKPPKRPFRRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43776-1", "uniprot_id": "SYNC_HUMAN", "id": "O43776-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-------------------------------------------------------MVLAELYVSDREGSDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWNVISKSQLKNIKK---MWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAG-SIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDX3-1", "uniprot_id": "A0A8N7TDX3_DANRE", "id": "A0A8N7TDX3-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "MRPHQLVCVCVECQEARRTNRFNGAFTVINSRRTEPDSTPLRSTECNMADEGVGKMSIKELYVSDKQGSDA-DGDGSEQKPFKTPLKALLFAGKEP---FPVIYVDSQ--KEGERWTVISKTQMKNTKK---AFHREQMKNESKDKKEAEDAERREKNLEEAKKITIENDSSLPEPKTVKIDKLEALREQRVKVFGWVHRLRRQGKNLLFIVLRDGTGFLQCVLTDKLCQCYNGLVLSTESSVALYGTVKPVPEGKQAPGGHELHCDFWELVGLAPAGGADNLLN---EESDVDVQLNNRHMMIRGENVSKILKVRSAVTQCFRDHFFSRGYCEITPPTLVQTQVEGGSTLFGLNYFGENAYLTQSSQLYLETCIPALGDTFCIAQSYRAEQSRTRRHLSEYTHIEAECPFMSYEDLLNRLEDLVCDVVDRVLKSPAA-PLLYDINPDFKPPKRPFKRMNYTEAIDWLKEHNIKKDDGTFYEFGEDIPEAPERLMTDSINETILLCRFPAEIKSFYMQRCPEDRRLTESVDVLMPNVGEIVGGSMRIWDSDELLEGYKREGIDPTPYYWYTDQRKFGTCPHGGYGLGLERFLTWLLNRHHIRDVCLYPRFIQRCRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V434-1", "uniprot_id": "Q9V434_DROME", "id": "Q9V434-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MPADQLA------------ELTLGAIFTSEKKGSDE-SGDGSESKPFKTILQAMRHAGKEP---FPTIYVDTKDPNAAEPYEPAAKSQLKKIQK---LFVRESHKNADKLQREAEDAEKRQQNLEDARKVKISEDPSLPVARKIRIYEGTANRDSRVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTESSVVLFGTLKLVPEGKTAPGGHELNVDYWELIGLAPPGGADAILN---EEAQPDVQLDNRHIMIRGENTSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLYLETCLPALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDVVDRVLKSPWG-YLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPERKMTDTINEPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGGSMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIREVCLYPRFLDRCRP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38707-1", "uniprot_id": "SYNC_YEAST", "id": "P38707-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "---------------------------------------------------------MSSLYIKEATGVDELTTAGSQDHPFKTPAYALFASQQKSDATEPKLFVFKT---EDNEYQEISASALKKARKGCDGLKKKAVKQKEQELKKQQKEAENAAKQLSALNITIKEDESLPAAIKTRIYDSYSKVGQRVKVSGWIHRLRSN-KKVIFVVLRDGSGFIQCVLSGDLALAQQTLDLTLESTVTLYGTIVKLPEGKTAPGGVELNVDYYEVVGLAP-GGEDSFTNKIAEGSDPSLLLDQRHLALRGDALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLTQSSQLYLETCLASLGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLEDPIAGPLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFKFGDDIAEAAERKMTDTIGVPIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNVGEITGGSMRIDDMDELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCDRFTVRDCSLYPRFSGRCKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .: * * *::.:**** *: ::. * ::* . : : : : :*: :* :: *. .: :: :. .. : .* :: *.:* *** . :* . .**** **:**** : *.::*:.****:*::**** ..*. : : *: **:*.::* : *:** **** ** *::*::**** ** * : * * :: .: *::**: :**: * ::* *: : :..* : . *:*.* :********:*** :.*:**:*:************:.:***.: * :*:***:*:*****:*:**:*** .*::::***.::* *: . *: :*:.* . :: ::**:*:.*: ** *::* :** **.*:::.:::* ::**:**.**.** ***:*. .*:* ***.*******:** :* *:*******:******.***** * :*:: *:******. .***: *** :** ******:* **:* *: :*. :*: .***** ** *", "identical_positions": 233, "similar_positions": 175, "identity": "37.82%" }, { "cls_id": "homologset.agr.SGD:S000001062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ92-1", "uniprot_id": "A0A8I6GJ92_RAT", "id": "A0A8I6GJ92-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE-NLLRVSES--VVFTDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKELNHCLSLRTYLVGNSLTLADLCVWATLKGNAACQEHLRQSKTLVHVNRWYGFLEAQQAFRSVGTKWD----------ASANKATGAPDRKQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIEEGKAYVDDTPADEMKAEREQRIESRHRKNPVEKNLQMWEEMKRGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRALCKKVIDPVAPRYVALLKKEVIPVNILDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNPDGKITSLDAKLNLENKDYKKTTKITWLAETTQ-ALPVPAVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETGSAPKERPAAAVSAPCAAAEDAAILYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDAVRDLKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYRPGNPPTAAVQTVSTKSPSNTGEYT------------SLYNKVAAQGELVRKLKAEKAPKAKINDAVECLLSLKAEYKEKTGKEYVPG-------QLPAS--QNSHSSPVS--------------------------------------------------------NAKPV-----------GSETPEAKLLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTG---------------IEYKPVSATG-AEDKD---------KKKKEKENKSEKQ---------------------------NKPQKQNDGQGKDSSK-SQGSGLS----SGGAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQGALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTLEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDP-KTPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITNTLSEEDREALMAKCNEYRRRLLGADIRARVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAESKLKGVLEDIQLNLFTRASEDLKSHMVVSDTLEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGC7-1", "uniprot_id": "SYEP_MOUSE", "id": "Q8CGC7-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE-NLLRVSET--VAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWD----------VSGNRATVAPDKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVVPVNVLDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWLAESTH-ALSIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETSSAPKERPAPAVSSTCATAEDSSVLYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPSAAAVQTVSTKSSSNTVEST------------SLYNKVAAQGEVVRKLKAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPG-------QPPAS--QNSHSNPVS--------------------------------------------------------NAQPA-----------GAEKPEAKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTG---------------IEYKPVSATG-AEDKD---------KKKKEKENKSEKQ---------------------------NKPQKQNDGQGKDSSK-SQGSGLS----SGGAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDP-KTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07814-1", "uniprot_id": "SYEP_HUMAN", "id": "P07814-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MATLSLTVNSGDPPLGALLAVEHVKDDVSISVEEGKE-NILHVSEN--VIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWD----------VSTTKARVAPEKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLAETTH-ALPIPVICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEATK---NETSAPFKERPTPSLNNNCTTSEDSLVLYN-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPPAEIGQNISSNSSASILESK------------SLYDEVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGKEYIPG-------QPPLS--QSSDSSPTR--------------------------------------------------------NSEPA-----------GLETPEAKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSLIG---------------VEYKPVSATG-AEDKD---------KKKKEKENKSEKQ---------------------------NKPQKQNDGQRKDPSK-NQGGGLS----SSGAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDP-KIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQD-----LEPGAPSMGAKSLCIPFKPLCELQPGAKCVC--GKNPAKYYTLFGRSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARK1-1", "uniprot_id": "A0A8M3ARK1_DANRE", "id": "A0A8M3ARK1-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MALNLTFNSSNPPLGALLTAEHVKGSVNLSVEEGKD-TMLHVSDQ--VQFSDVNSITRYLARVAPALGLYGSNMMEQTEVDHWLEFSARRLCGQSDLSSALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQAKP---SSHPHLCRWFSFLSSQVPFSSVGSKWASKV-------SASKAASVEKDKKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTILRMGEKLLQEGKAYIDDTPPDIMKQEREQRAESRNRNNSVEKNMQMWEEMKKGTEFGQTCCMRAKIDMNSNNGCLRDPALFRCKNAAHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVIEALGLRKPYIWEYARLNLNNTVLSKRKLTWFVDKGYVDGWDDPRFPTVRGVLRRGMTVDGLKQFIAAQGGSRSVVNMEWDKIWAFNKKLPVSCKKVIDPVAPRFTALLSSQVIPVCVSEAKETMKEVPKHPKNADVGLKQVWYGPKVFIEGADAETFTEGEIVTFINWGNIIITKIHRDSSGAILSLDGHLNLENTDYKKTTKITWLAESSR-ASFVPTVCVNYQHLITKPVLGKDDDFKDYINKNSKIEEKMIGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCRESPCVLLYIPDGHTKEMPTAGSKDKSKSQPAKPVKAEPAPPSKAKSAPSSNPTPSAPGDASVILSNIMAQGDAVRQLKTEKAPKEQVDAAVKQLLALKSEFKQLTGQEYKPGMTLPASAPVQKSSAPTLAAAPGPASTGCPFTRVSEQGELVRKLKAEKAPKEQIDAAVKQLLAFKAEFKQLTGQDYKPGMAPPTASPPEPAPSSNSSPAGIYERVSEQGELVRKLKAEKAPKDQVDAAVKQLLALKAEYKQGTGQDYKPGVPTAKASPASSSSPAQLTVASTPAASAPSDSSPQAIYDRVSQQGDLVRKLKTEKAPKDQVDAAVKQLLNLKAEYKQQTGQEYKPG-------APPSSGSATAQSNPTPPQSS----------------------------------------------------SSQPQ-----------SSSSPQAQALFSDIAQQGEQVRRLKTEKAPKEQVDKAVKTLLELKGQYKALTG---------------EEYKPVTTPGNSGGED---------KSRKERENKSEKQ---------------------------GGGGGGGRKQQKGGEKPQQGQESG----AGGAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWDAIKEFFDREIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSRMFEIVFEDP-KKPGEKQLAYQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACLQVIIIPCGITATLPEAEKDLLLDQCSKYLSRLQKADIRVKADLRDNYSPGWKFNHWELKGVPIRFEVGPKDLKQGQFVAVRRDTGEKITVKEADAEKKIPNLLEEIQNNLFKRASDDLNKHMVVADTMEQFQKDLDQGRIVQIPFCGGIECEDWIKKTTAKDQD-----LEPGAPSMGAKSLCIPFKPLKNLQAGQMCVS--GKEPAQYYTLFGRSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28668-1", "uniprot_id": "SYEP_DROME", "id": "P28668-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MSIKLKANLNNPPISGLATAHLINGTVPVEIVWSKEETSLQFPDNRLLVCHSNNDVLRALARAAPDYKLYGETAIERTQIDHWLSFS---LTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSR---YEFLAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAKVKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFN-------KKVIDPIAPRYTALEKEKRVIVNVAGAKVERIQVSVHPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDDPSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSGLKVNAPDAKAT--KKASSPVSSSGQASELDSQISQQGDLVRDLK-------------SKKAAKDQIDVAVKKLLALKADYKSATGKDWKPGQTSASSAPVPAASS-----------------------------------------------------------------------------SSANDAVSVNASIVKQGDLVRDLKGKKASKPEIDAAVKTLLELKAQYKTLTGQDWKPGTVPTTAAPSASAAPSVGVNDSVA-----------QILSQITAQGDKVRELKSAKADKATVDAAVKTLLSLKADYKAATGSDWKPGTTAPAPAAAPVKVKQEKNPDPASVLTVNTLLNKIAQQGDKIRQLKSAKSEKSLVEAEVKLLLALKTDYKSLTGQEWKPGTVAPAPTTVNVIDLTGGDSGSDVGSVLSKIQAQGDKIRKLKSEKAAKNVIDPEVKTLLALKGEYKTLSGKDWTPDAKSEPAVVKKEASPVSMASPAKDELTQEINAQGEKVRAAKGNKAAKEVIDAEVAKLLALKAKYKEVTGTDFPVAGRGGGGGGGSAKKAPKEAQPKPAKPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDP-ETQ-QKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEE-----AEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38708-1", "uniprot_id": "YHI0_YEAST", "id": "P38708-1", "name": "Putative proline--tRNA ligase YHR020W", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVSEAFAKLCVNEKPPAESAVAVKSLV-----FKPKTPKSATP-VPIVVVALQSTTTPSALIANAT-----------------------------SSKDPRLARDDLVK------QAFQSESARAFILG-------------------DLAN------------------------------------------------------------------------ATSNFHLLIDHELGTVDGDTILQLNDSTYMKK------SDMMKFLNNFE--------------------DSQKVVDFS------------------QEVSKETATE-------------------------------------GKKQQKKQQPSKAG----TAAAAAAAALEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQP-VLNEGQKCIK--CERIAVNYCMFGRSY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . .* :: . : .*** *: :* * :. * . :: .. : * : *: :: :. : * . . . . . . :*: : :*: .. *. . :: : ::: : . * . ::: .: * * * .* . . :. . :*: . * ::. **.*::**.**::*:*:****:** :::**. *: :** :*. :**::.***:***. .***** *: .*********::*.::* ****:********** *******:****::**** .*******:* **************:*. ::* .***:**::** ** .*:*:***:*************:*** *.:*. :**.***.**********:* :: *:* * .** ***::**.***: *:*.** ***:**:*: .* :::* *** : :: : . ** .:* * .***:*****.::****:*:*:*:**:*:: *.*.***: :* .: : * :: :** :: ::.:*.: : .* * *: .: *:** :.**: ** :*: :: : **:**********. : . *: . . * :*****", "identical_positions": 258, "similar_positions": 200, "identity": "14.04%" }, { "cls_id": "homologset.agr.SGD:S000001063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWY3-1", "uniprot_id": "RS27L_MOUSE", "id": "Q6ZWY3-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71UM5-1", "uniprot_id": "RS27L_HUMAN", "id": "Q71UM5-1", "name": "Ribosomal protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24051-1", "uniprot_id": "RS27L_RAT", "id": "P24051-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42677-1", "uniprot_id": "RS27_HUMAN", "id": "P42677-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWU9-1", "uniprot_id": "RS27_MOUSE", "id": "Q6ZWU9-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VBU9-1", "uniprot_id": "Q9VBU9_DROME", "id": "Q9VBU9-1", "name": "40S ribosomal protein S27", "aln": "MPLAKDLLHPLPAEEKRKHKLKRLVQHPNSYFMDVKCPGCYRITTVFSHAQGVVVCAGCATILCQPTGGRAKLTEGCSFRRKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38711-1", "uniprot_id": "RS27B_YEAST", "id": "P38711-1", "name": "Small ribosomal subunit protein eS27B", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:***** .* :*** * *** *.***:******* .********* .* * .*:*:** ****:*:*:** ***** ", "identical_positions": 54, "similar_positions": 14, "identity": "64.29%" }, { "cls_id": "homologset.agr.SGD:S000001064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKM7-1", "uniprot_id": "RAB37_MOUSE", "id": "Q9JKM7-1", "name": "Ras-related protein Rab-37", "aln": "---------------------------------------------------MTGTPGAATAGDG-EAPERSPPFSPNY--DLTGKVMLLGDSGVGKTCFLIQFK-DGAFLSGTFIATVGIDSRNKVVTVDGAR------VKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNQSSFDNIRAWLTEIHEYAQR----DVVIMLLGNKADVSSERVIRSE-DGETLAREYGVP-----FMETSAKTGMNVELAFLAIAKELKYRAGRQPDE---PSFQIR---DYVESQKKRSSCCSFV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0G7-1", "uniprot_id": "D4A0G7_RAT", "id": "D4A0G7-1", "name": "small monomeric GTPase", "aln": "---------------------------------------------------MTGTPGAATAGDG-EAPERSPPFSPNY--DLTGKVMLLGDSGVGKTCFLIQFK-DGAFLSGTFIATVGIDFRNKVVTVDGAR------VKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNQSSFDNIRAWLTEIHEYAQR----DVVIMLLGNKADVSSERVIRSE-DGETLAREYGVP-----FMETSAKTGMNVELAFLAIAKELKYRAGKQPDE---PSFQIR---DYVESQKKRSSCCSFA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AX2-1", "uniprot_id": "RAB37_HUMAN", "id": "Q96AX2-1", "name": "Ras-related protein Rab-37", "aln": "---------------------------------------------------MTGTPGAVATRDG-EAPERSPPCSPSY--DLTGKVMLLGDTGVGKTCFLIQFK-DGAFLSGTFIATVGIDFRNKVVTVDGVR------VKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQR----DVVIMLLGNKADMSSERVIRSE-DGETLAREYGVP-----FLETSAKTGMNVELAFLAIAKELKYRAGHQADE---PSFQIR---DYVESQKKRSSCCSFM--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IQZ8-1", "uniprot_id": "A0AC58IQZ8_DANRE", "id": "A0AC58IQZ8-1", "name": "small monomeric GTPase", "aln": "MVKFIRLCVSAAHETAGEQLMERMTVEDLQRIFSSGLEMQEQTEAADPDSAYGSSPGDTDTEDGGHALTSSSSTTLVYNQELMHKTILVGDSGVGKTSLLVQFD-QGKFISGSFSATVGIGFTNKVVTVDNMK------VKLQIWDTAGQER--FRSVTHAYYRDAQALLLLYDITRKSSFDNIRAWLTEIYEYAQK----DVVIMLLGNKSDMAAERVITHE-EGEKLAKEYGVP-----FMETSAKTGVNVELAFHAIARELKHRNLEQPHE---PKFKIH---DYIESQKQKSNCCGGIM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8QZZ8-1", "uniprot_id": "RAB38_MOUSE", "id": "Q8QZZ8-1", "name": "Ras-related protein Rab-38", "aln": "--------------------------------------------------------------------------MQTPHKEHLYKLLVIGDLGVGKTSIIKRYV-HQNFSS-HYRATIGVDFALKVLHWDPETV-----VRLQLWDIAGQER--FGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVG----WFETSAKENINIDEASRCLVKHILANECDLLES-IEPDIVKP----HLTSPKVVS-CSGCAKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63483-1", "uniprot_id": "Q63483_RAT", "id": "Q63483-1", "name": "Ras-related protein Rab", "aln": "--------------------------------------------------------------------------MQTPHKEHLYKLLVIGDLGVGKTSIIKRYV-HQNFSS-HYRATIGVDFALKVLHWDPETV-----VRLQLWDIAGQER--FGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLVNNGLKMDQFCKEHGFVG----WFETSAKENINIDEASRCLVKHILANECDFIES-IEPDIVKP----HLTSPKVVS-CSGCAKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57729-1", "uniprot_id": "RAB38_HUMAN", "id": "P57729-1", "name": "Ras-related protein Rab-38", "aln": "--------------------------------------------------------------------------MQAPHKEHLYKLLVIGDLGVGKTSIIKRYV-HQNFSS-HYRATIGVDFALKVLHWDPETV-----VRLQLWDIAGQER--FGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVG----WFETSAKENINIDEASRCLVKHILANECDLMES-IEPDVVKP----HLTSTKVAS-CSGCAKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8V4-1", "uniprot_id": "A0AB13A8V4_DANRE", "id": "A0AB13A8V4-1", "name": "Ras-related protein Rab", "aln": "--------------------------------------------------------------------------MHNNQKEHLYKILVIGDLGVGKTSIIKRYV-HQTYST-NYRATIGVDFALKVLNWDSET------VRLQLWDIAGQER--FGNMTRVYYREAMGAFIVFDVTRPATFEAVSKWKEDLDSKLILSNGQSIATVLLANKCDQNRDFLTNNGLKMDQYCRENGFVG----WFETSAKENVNINDAANFLVKHIIASENDILKS-VVPDTISP----QLNSDKEMT-CSACFKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T7H0-1", "uniprot_id": "A0A8N7T7H0_DANRE", "id": "A0A8N7T7H0-1", "name": "Ras-related protein Rab", "aln": "-----------------------------------------------------------------------------MQKEHLFKVLVIGDLGVGKTSIIKRYV-HQIFSQ-HYRATIGVDFALKVLHWDSQTV-----VRLQLWDIAGQER--YGNMTRVYYREAVGALIVFDVTRSSTFDAVLKWKDDLDLKVSLNNGKPVPAVLLANKSDQSREGLCSQIPKLDTFCKENGFVG----WFETSAKENSNIEAAAKCLVDHILAHEENIVNN-TDPDVVALPGYNNNTKERVRSRCMTCSKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q13637-1", "uniprot_id": "RAB32_HUMAN", "id": "Q13637-1", "name": "Ras-related protein Rab-32", "aln": "----------------------------------------------------------MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYV-HQLFSQ-HYRATIGVDFALKVLNWDSRTL-----VRLQLWDIAGQER--FGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKD-SSQSPSQVDQFCKEHGFAG----WFETSAKDNINIEEAARFLVEKILVNHQSFPNEENDVDKIKL----DQETLRAENKSQCC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38763-1", "uniprot_id": "YHI2_YEAST", "id": "P38763-1", "name": "Uncharacterized protein YHR022C", "aln": "-----------------MSVRLSYGASLASIPRCFDLKSSKITVMGDDHSGKTSLVRSWLGSSFQISDANRYRVSDLYHKTIQFDTLVKYYRTFGVKGQLPNYAGFKAKNSGTIYESCGNFLEERLINANKSTAQRRTSIDVQVFDTNQMEVSYLSELTTLQIRQSDAIILCFDSTNDSSLASLESYICIIH-HVRLECELDIPIIIACTKCDLDSERTITHE-KVLTFIQELGFSPGNLDYFETSSKFNVNVEDLFLAVLLKIEKSKSDRRKLL-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: .* . : .: : * ::: : : :*::* * .:* ::: . :: :* :. ::: : : : : :: .*.* : . :* *. ::***:* . *:: : .: . ", "identical_positions": 16, "similar_positions": 53, "identity": "5.26%" }, { "cls_id": "homologset.agr.SGD:S000001065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02564-1", "uniprot_id": "MYH7_RAT", "id": "P02564-1", "name": "Myosin-7", "aln": "--------------------------------------------MADREMAAFGAGAPFLRKSEKERLEA--------------QTRPFDLKKDVFVPDDKEEFVKAKIVSRE-GGKVTAETENGKT-VTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAQVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDR-----------------------------------------SKKDQ-TPGKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILS-NKKPELLDMLLITNNPYDYAFFSQGET-TVASIDDSEEHMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAIGALAKSVYEKMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN-IKGKQEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFAN--------------------------------------------------YAGADAP-VDKGKGK--AKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETE-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKNNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGAKGLNEE-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z83-1", "uniprot_id": "MYH7_MOUSE", "id": "Q91Z83-1", "name": "Myosin-7", "aln": "--------------------------------------------MADAEMAAFGAAAPFLRKSEKERLEA--------------QTRPFDLKKDVFVPDDKEEFVKAKIVSRE-GGKVTAETENGKT-VTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDR-----------------------------------------SKKDQ-TPGKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILS-NKKPELLDMLLITNNPYDYAFISQGET-TVASIDDSEELMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVSYAIGALAKSVYEKMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN-VKGKQEAHFSLVHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFAN--------------------------------------------------YAGADAP-ADKGKGK--AKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETE-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGAKGLNEE-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12883-1", "uniprot_id": "MYH7_HUMAN", "id": "P12883-1", "name": "Myosin-7", "aln": "--------------------------------------------MGDSEMAVFGAAAPYLRKSEKERLEA--------------QTRPFDLKKDVFVPDDKQEFVKAKIVSRE-GGKVTAETEYGKT-VTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDR-----------------------------------------SKKDQ-SPGKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILS-NKKPELLDMLLITNNPYDYAFISQGET-TVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRN-IKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFAN--------------------------------------------------YAGADAP-IEKGKGK--AKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETE-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGTKGLNEE-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02566-1", "uniprot_id": "MYH6_MOUSE", "id": "Q02566-1", "name": "Myosin-6", "aln": "--------------------------------------------MTDAQMADFGAAAQYLRKSEKERLEA--------------QTRPFDIRTECFVPDDKEEYVKAKVVSRE-GGKVTAETENGKT-VTIKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDR-----------------------------------------SKKENPNANKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILS-NKKPELLDMLLVTNNPYDYAFVSQGEV-SVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKASDMTFKAKLYDNHLGKSNNFQKPRN-VKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFST--------------------------------------------------YASADTGDSGKGKGG--KKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEME-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGAK-KMHDEE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02563-1", "uniprot_id": "MYH6_RAT", "id": "P02563-1", "name": "Myosin-6", "aln": "--------------------------------------------MTDAQMADFG-AARYLRKSEKERLEA--------------QTRPFDIRTECFVPDDKEEYVKAKIVSRE-GGKVTAETENGKT-VTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDR-----------------------------------------SKKDNPNANKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILS-NKKPELLDMLLVTNNPYDYAFVSQGEV-SVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN-VKGKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLMATLFST--------------------------------------------------YASADTGDSGKGKGG--KKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSGKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSHMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEME-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGAKQKMHDEE---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13533-1", "uniprot_id": "MYH6_HUMAN", "id": "P13533-1", "name": "Myosin-6", "aln": "--------------------------------------------MTDAQMADFGAAAQYLRKSEKERLEA--------------QTRPFDIRTECFVPDDKEEFVKAKILSRE-GGKVIAETENGKT-VTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDR-----------------------------------------GKKDNANANKG-TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILS-NKKPELLDMLLVTNNPYDYAFVSQGEV-SVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN-IKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSS--------------------------------------------------YATADTGDSGKSKGG--KKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKG-----TEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL--EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE-AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR--------DIGAKQKMHDEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NBP6-1", "uniprot_id": "A0A8M1NBP6_DANRE", "id": "A0A8M1NBP6-1", "name": "Myosin-7", "aln": "--------------------------------------------MGDAEMSVFGAAAPYLRKSEKERLEA--------------QTKAFDLKKECFVPDAIEEFVKATVVSRE-GDKVTVETQGGKT-VTVKEADVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNQEVVIAYRGKE------------RTEAPPHIYSISDNAYQYMLADRENQSILITGESGAGKTVNTKRVIQYFASVAASG--------------------------------------------GKKDQDKNKG-TLEDQIIQANPALEAFGNAKTIRNDNSSRFGKFIRIHFDTRGKLASADIETYLLEKSRVTFQLKAERDYHIFYQILS-NKKPEILEMLLVTSNPYDYAFISQGET-TVPSIDDSDELMATDSAFDILGFTQEEKNSVYKLTGAIMHYGNMKFKQKQREEQAEADGTEDADKSAYLMGLNSADLIKGLCHPRVKVGNEWVTKGQNVQQVNYAIGALSKAVYEKMFLWMVVRINQSLE-TKQPRQYFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKASDATFKAKLYDNHLGKSNNFQKPRL-VKGKPEAHFALVHYAGTVDYNINNWLVKNEDPLNETVVGLYQKSSLKLLSNLFAN--------------------------------------------------YAGADSATGDGGKKE-KKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCLIPNETKTPGAMENPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRILNPAAIPEGQFIDSKKG-----AEKLLGSLDIDHQQYRFGHTKVFFKAGLLGQLEEMRDERLSKIITGIQAKSRGLLSRAEYIKMVERRDALLVIQWNVRAFMAVKN-WPWMKLFFKIKPLLRSAEAEKEMANMKEEFLKLKEAYAKSEARRKELEEKMVTLLQEKNDLQLQVQAEQDNLCDAEERCEGLIKNKIQMEAKAKELTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDDIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEEKLKKKDFEISQLNSKIDDEQSIIIQLQKKLKELQARVEELEEELEAERAARAKVEKPRADLARELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELRLELDDVASSMEHIVKSKTNMEKVNRTLEDQMNEYRNKCEEYQRSLNDFTTQKAKLQAENDEFSRQLEEKESLVSQLTRGKNSFSQQLEDLKRQLDEEIKAKNALAHALQSARHDTDLLREQYEEEQE-AKAELQRSMSKANTEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNTAAASLDKKQRHFDKIISEWKQKYEESQCELESSQKEARSLSTELFKLKNSYEESMDHLETMKRENKILQEEISDLTEQLGEGGKTIHELEKVRKQLEQEKAEIQAALEEAEGSLEHEEGKILRTQLEFNQIKADIERKLSEKDEEMEQVKRNQQRTIDTLQSALESETHSRNEALRIKKKMEGDLNEMEIQLSQANRQAAEAQKQLKSVQAHLKDSQLQLDDSLRSNDDLKENTAIVERRNALLQAELEELRAVLEQTERGRKLAEQELLDVTERVQLLHSQNTSLINQKKKLETDLSQFQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELECEVEAEQKRSSESVKGIRKYERRIKELTYQTEEDRKNIARLQDLVDKLQLKVKAYKRAAEESEEQANVHLGKFRKLQHELDEAEERADIAESQVNKLRAKSR--------DVGPKKAFDEE----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QZW1-1", "uniprot_id": "F1QZW1_DANRE", "id": "F1QZW1-1", "name": "", "aln": "--------------------------------------------MGDAQMAEFGAAASYLRKSDRERLEA--------------QTRPFDMKKECFVPDPDEEYVKASIVSRE-GDKVTVQTEKRKT-VTVKEADIHPQNPPKFDKIEDMAMFTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNQEVVVAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAGGS-------------------------------------------AKKEGAEKKG-TLEDQIIQANPALEAFGNAKTIRNDNSSRFGKFIRIHFGASGKLASADIETYLLEKSRVTFQLKAERDYHIFYQILS-QRKPELLEMLLITNNPYDYAYISQGET-TVASINDGEELLATDEAFDVLGFTQEEKNGIYKLIGAIMHFGNMKFKQKQREEQAEADGTEDGDKVAYLMGLNSADLIKGLCHPRVKVGNEWVTKGQNVQQVYYAIGALAKSVYEKMFLWMVVRINQSLD-TKQPRQYFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKASDSTFKAKLYDNHLGKSNNFQKPRA-IKGKPESHFSLVHYAGTVDYNINNWLVKNKDPLNETVVGLFQKSTVKLLSMLFAN--------------------------------------------------YAGTESDNGKGGKGGGSKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMENPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGQLEEMRDDRLSLIISGIQARSRGLLARVEFQKIVERRDALLVIQWNVRAFMGVKN-WPWMKLFFKIKPLLKSAEAEKEMANMKDEFAKLKEAYAKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLCDAEERCDQLIKNKIQLEAKAKELTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDDIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLTQESLMDLENDKQQLEERLKKKDFEISQLNGKIEDEQTICIQLQKKLKELQARIEELEEELEAERAARAKVEKQRADLARELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELRLELDDVVSNMEHVVKTKANLEKMTRSLEDQMNEYKTKYEEGQRCINDFTMQKSKLQSENGELSRQLEEKDSLVSQLTRSKMSYTQQIEDLKRQLEEETKAKSALAHAVQSARHDTDLLREQYEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQETEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDLERSNAAAAALDKKQRNFDKVLSEWKQKFEESQAELESSQKEARCLSTELFKLKNSYEEALDHLETMKRENKNLQEEISDLTEQLGEGGKSIHELEKMRKQLEQEKSEIQSALEEAEASLEHEEGKILRAQLEFSQIKADIERKLAEKDEEMEQSKRNLQRTIDTLQSSLESETRSRNEALRIKKKMEGDLNEMEIQLSQANRQAAEAQKQLKSVHAHMKDAQLQLDDSLRTNEDLKENTAIVERRNNLLQAELEELRAALEQTERGRKLAEQELLDTSERVQLLHSQNTSLLNQKKKLETDISQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELESEVESEQKKSSEAVKGIRKYERRIKELTYQTEEDRKNLARLQDLVDKLQLKVKAYKRAAEEAEEQANTNLSKFRKIQHELDEAEERADIAESQVNKLRAKSR--------DVSSKKGHDQE----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7H9-1", "uniprot_id": "A0ACD6B7H9_DANRE", "id": "A0ACD6B7H9-1", "name": "", "aln": "--------------------------------------------MGDAVMAEFGSAAPFLRKSDKERLEA--------------QTRIFDMKKECFVPDPEVEYVKASITSRD-GDKVTVDTEYGKT-LTFKECDVHPQNPPKFDKIEDMAMFTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDSSVVKAYRGKK------------RTEAPPHIFSISDNAYQYMLSDRENQSVLITGESGAGKTVNTKRVIQYFASIAAVSG-------------------------------------------KKDAASEKKG-TLEDQIIQANPALEAFGNAKTIRNDNSSRFGKFIRIHFGVSGKLASADIETYLLEKSRVTYQLKAERDYHIFYQILS-QKKPELLEMLLITNNPYDYSYISQGET-QVASIDDAEELIATDDAFDVLGFTQDEKSGIYKLTGAIMHFGNMKFKQKQREEQAEADGTEDADKVAYLMGLNSADLIKGLCHPRVKVGNEWVTKGQNVQQVYYSIGALAKSVYEKMFLWMVVRINQSLD-TKQPRQYFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFIDFGMDLQACIELIEKPM---GIMSILEEECMFPKASDQTFKAKLYDNHLGKNPTFQKPRI-VKGRPEAHFALVHYAGTVDYNISNWLVKNKDPLNETVVGLFQKSTVKLLSFLFAG--------------------------------------------------YSGADSAQDSKGGKGGGKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCLIPNETKTPGAMENPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRILNPSANPEGQFIDNKKA-----AEKLLGSLDIDHNQYKLGHTKVFFKAGLLGTLEEMRDDRLALIITGIQARARGILSRLEFQKIVERRDSLLVIQWNVRAFMGVKN-WPWMKLYFKIKPLLKTAETEKEMANMKEEFTKLKEAYAKSEARKKELEEKMVSLLQEKNDLQLAVQSEQDNLVDAEERCEGLIKSKIQLEAKAKELTERLEDEEEMNAELVAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDEIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLTQESIMDLENDKQQMEEKLKKKDFEISQLNSKIEDEQALGAQLQKKLKELQARIEELEEELEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADSVADLGEQIDNLQRVKQKLEKEKSELKLELDDVVSNMEQIVKSKSNLEKMCRTLEDQMSEYRTKAEEGQRTINDFTMQKAKLQTENGELSRQLEEKDSLVSQLTRGKQSYTQQIEDLKRQLEEEVKAKNALAHAVQSARHDSDLLREQFEEEQE-AKAELQRSLSKTNSEVAQWRTKYETDAIQRTEELED-AKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKVLAEWKQKYEESQTELESAQKESRSLSTELFKLKNSYEEVLDQLETMKRENKNLQEEISDLTEQLGETGKSIHELEKIRKQLEQEKAEIQTALEEAEGSLEHEEGKILRAQLEFNQVKADIERKLSEKDEEMEQAKRNQQRVVDTLQSSLESETRSRNEALRLKKKMEGDLNEMEIQLSQANRQASEAQKQLKSLHGHVKDSQMQLDDALRGNDDLKENIAIVERRNNLLQAELDELRSLVEQTERGRKLAEQELMDVSERVQLLHAQNTSLLNQKKKLEGDNTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELENEVELEQRKASESVKGVRKYERRIKELTYQTEEDRKNLARLQDLVDKLQLKVKSYKRAAEEAEEQANSNLGKFRKLQHELDEAEERADIAESQVNKMRAKSR--------DSGPKKGHDEE----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5SX39-1", "uniprot_id": "MYH4_MOUSE", "id": "Q5SX39-1", "name": "Myosin-4", "aln": "-------------------------------------------MSSDAEMAVFGEAAPYLRKSEKERIEA--------------QNKPFDAKSSVFVVDAKESYVKATVQSRE-GGKVTAKTEGGAT-VTVKDDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDK-----------------------------------------KKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-NKKPELIEMLLITTNPYDFAYVSQGEI-TVPSIDDQEELMATDTAVDILGFSADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSMYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSG------------------------------------------------GQAAEAEG-GG--GKKGG-KKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFKKMMERRESIFCIQYNVRAFMNVKH-WPWMKLYFKIKPLLKSAETEKEMANMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSTQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQE-AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--VISEE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q29RW1-1", "uniprot_id": "MYH4_RAT", "id": "Q29RW1-1", "name": "Myosin-4", "aln": "-------------------------------------------MSSDAEMAVFGEAAPYLRKSEKERIEA--------------QNKPFDAKSSVFVVDAKESYVKATVQSRE-GGKVTAKTEGGAT-VTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDK-----------------------------------------KKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMS-NKKPELIEMLLITTNPYDFAYVSQGEI-TVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAMYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSG------------------------------------------------GQAAEAEG-GG--GKKGG-KKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMNVKH-WPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQE-AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--VISEE---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y623-1", "uniprot_id": "MYH4_HUMAN", "id": "Q9Y623-1", "name": "Myosin-4", "aln": "-------------------------------------------MSSDSEMAIFGEAAPFLRKSEKERIEA--------------QNKPFDAKTSVFVVDPKESYVKAIVQSRE-GGKVTAKTEAGAT-VTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK-----------------------------------------KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS-NKKPELIEMLLITTNPYDFAFVSQGEI-TVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSG------------------------------------------------AQTAEAEG-GG--GKKGG-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKH-WPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR--------EVHTK--VISEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SX40-1", "uniprot_id": "MYH1_MOUSE", "id": "Q5SX40-1", "name": "Myosin-1", "aln": "-------------------------------------------MSSDAEMAVFGEAAPYLRKSEKERIEA--------------QNKPFDAKSSVFVVDAKESFVKATVQSRE-GGKVTAKTEGGTT-VTVKDDQVYPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK-----------------------------------------KKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-NKKPDLIEMLLITTNPYDYAFVSQGEI-TVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKVEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSMKTLAYLFSGA-----------------------------------------------AAAAEAES-GGGGGKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLARVEYQKMVERRESIFCIQYNVRAFMNVKH-WPWMKLYFKIKPLLKSAETEKEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE-AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--IISEE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12882-1", "uniprot_id": "MYH1_HUMAN", "id": "P12882-1", "name": "Myosin-1", "aln": "-------------------------------------------MSSDSEMAIFGEAAPFLRKSERERIEA--------------QNKPFDAKTSVFVVDPKESFVKATVQSRE-GGKVTAKTEAGAT-VTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK-----------------------------------------KKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-NKKPDLIEMLLITTNPYDYAFVSQGEI-TVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFVG------------------------------------------------ATGAEAEA-GG--GKKGG-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKH-WPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE-AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--IISEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UW82-1", "uniprot_id": "MYH2_MOUSE", "id": "G3UW82-1", "name": "Myosin-2", "aln": "-------------------------------------------MSSDAEMAVFGEAAPYLRKSEKERIEA--------------QNRPFDAKTSVFVAEPKESFVKGTIQSKD-AGKVTVKTEAGAT-LTVKEDQIFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDK-----------------------------------------KKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS-NKKPELIEMLLITTNPYDYPFVSQGEI-SVASIDDQEELMATDSAIDILGFTNDEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQGLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAMYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSANFQKPKV-VKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAYLFSG------------------------------------------------AQTAEAEASSGGAAKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQYIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNIRAFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDDLAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDERLKKKEFEMSNLQSKIEDEQAIGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTTQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNALAHALQSSRHDCDLLREQYEEEQE-SKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKIQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--IISEE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKX2-1", "uniprot_id": "MYH2_HUMAN", "id": "Q9UKX2-1", "name": "Myosin-2", "aln": "-------------------------------------------MSSDSELAVFGEAAPFLRKSERERIEA--------------QNRPFDAKTSVFVAEPKESFVKGTIQSRE-GGKVTVKTEGGAT-LTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK-----------------------------------------KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-NKKPELIEMLLITTNPYDYPFVSQGEI-SVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKV-VKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSG------------------------------------------------AQTAEGEG-AGGGAKKGG-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE-SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--VISEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13542-1", "uniprot_id": "MYH8_MOUSE", "id": "P13542-1", "name": "Myosin-8", "aln": "-----------------------------------------MSAGSDAEMAIFGEAAPYLRKSEKERIEA--------------QNKPFDAKTSVFVAEPKESYVKSVIQSKD-GGKVTVKTESGAT-LTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDK-----------------------------------------KKEE--SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS-NKKPELIEMLLITTNPYDYAFVSQGEI-TVPSIDDQEELMATDSAIDILGFSPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQCLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP-TKGKAEAHFSLVHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFST------------------------------------------------YASAEADG----GAKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGYLMRVEYQKMLLRRESIFCIQYNVRAFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQVEMNKKRETEFQKLRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEESLDHLETLRRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLAKFRKLQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--ISAE----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13535-1", "uniprot_id": "MYH8_HUMAN", "id": "P13535-1", "name": "Myosin-8", "aln": "-----------------------------------------MSASSDAEMAVFGEAAPYLRKSEKERIEA--------------QNKPFDAKTSVFVAEPKESYVKSTIQSKE-GGKVTVKTEGGAT-LTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK-----------------------------------------KKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS-NKKPDLIEMLLITTNPYDYAFVSQGEI-TVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKV-VKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFST------------------------------------------------YASAEADS----SAKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKA-----SEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR--------EVHTK--ISAE----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13541-1", "uniprot_id": "MYH3_MOUSE", "id": "P13541-1", "name": "Myosin-3", "aln": "-------------------------------------------MSSDTEMEVFGIAAPFLRKSEKERIEA--------------QNQPFDAKTYCFVVDSKEEYVKGKIKSSQ-DGKVTVETEDSRT-LVVKPEDVYAMNPPKFDKIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVDGYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDL-----------------------------------------AKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS-NKKPELIELLLITTNPYDYPFISQGEI-LVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKV-VKGKAEAHFSLVHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT------------------------------------------------FATTDADG----GKKKVA-KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKA-----CEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFLMRVEFQKMMQRRESIFCIQYNIRAFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL--EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEEMQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDACRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR--------DFTSSRMVVHESEE-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12847-1", "uniprot_id": "MYH3_RAT", "id": "P12847-1", "name": "Myosin-3", "aln": "-------------------------------------------MSSDTEMEVFGIAAPFLRKSEKERIEA--------------QNQPFDAKTYCFVVDSKEEYAKGKIKSSQ-DGKVTVETEDNRT-LVVKPEDVYAMNPPKFDKIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYTPEVVDGYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDL-----------------------------------------AKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS-NKKPELIELLLITTNPYDYPFISQGEI-LVASIDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKV-VKGKAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT------------------------------------------------FATTDADG----GKKKVA-KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKA-----CEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFLMRVEFQKMMQRRESIFCIQYNIRAFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL--EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEETQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANVHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR--------DFTSSRMVVHESEE-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11055-1", "uniprot_id": "MYH3_HUMAN", "id": "P11055-1", "name": "Myosin-3", "aln": "-------------------------------------------MSSDTEMEVFGIAAPFLRKSEKERIEA--------------QNQPFDAKTYCFVVDSKEEYAKGKIKSSQ-DGKVTVETEDNRT-LVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDL-----------------------------------------AKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS-NKKPELIELLLITTNPYDYPFISQGEI-LVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKV-VKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT------------------------------------------------FATADADS----GKKKVA-KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKA-----CEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKH-WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL--EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR--------DFTSSRMVVHESEE-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A568-1", "uniprot_id": "B8A568_DANRE", "id": "B8A568-1", "name": "", "aln": "-------------------------------------------MSTDAEMAVYGKAAIYLRKPEKERVEA--------------QNKPFDAKTACYVVDDKELYVKGTIKSKD-GGKVTVITLDTKEEKVVKEDDVHPMNPPKFDKIEDMAMMTHLNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKK------------RMEAPPHIFSVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGPE-----------------------------------------KKKEQASGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTSGKLASADIETYLLEKSRVTFQLPDERGYHIFYQMMT-NHKPELIEMTLITTNPYDFPMCSQGQI-TVASIDDKEELVATDTAIDILGFNNEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEEADKIGYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYERMFLWMVVRINQMLD-TKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKCNAFQKPKP-AKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNESVVQLYQKSSVKLLATLYPP-------------------------------------------------VVEETGG-----GKKGG-KKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRAYLMRREFVKMMERRDAIYTIQYNVRSFMNVKH-WPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEDLAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAAQDESIGKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKLKKKDFETSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTLEDQLSEIKSKNDENLRQINDLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-SKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQLGETGKSIHELEKSKKAVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRITDSMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLEADLVQIQSEVEDTVQEARNAEDKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADIAESQVNKLRAKSR--------DSGKG----KDAAE-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QEC8-1", "uniprot_id": "A0A8M9QEC8_DANRE", "id": "A0A8M9QEC8-1", "name": "", "aln": "-------------------------------------------MSTDAEMAVYGKAAIYLRKPEKERIEA--------------QNKPFDAKTACYVVDDKELYVKGTIKSRD-GGKVTVITLDTKEERVAKEDDVHPMNPPKFDKIEDMAMMTHLNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKK------------RMEAPPHIFSVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGPE-----------------------------------------KKKEQAAGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTSGKLASADIETYLLEKSRVTFQLPDERGYHIFYQMMT-NHKPELIEMTLITTNPYDFPMCSQGQI-TVASIDDKEELVATDTAIDILGFNNEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEEADKIGYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYERMFLWMVVRINQMLD-TKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKCNAFQKPKP-AKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNESVVQLYQKSSVKLLATLYPP-------------------------------------------------VVEETGG-----GKKGG-KKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRAYLMRREFVKMTERRDAIYTIQYNVRSFMNVKH-WPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEDLAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAAQDESIGKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKLKKKDFETSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTLEDQLSEIKSKNDENLRQLNDLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-SKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQIGETGKSIHELEKSKKAVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRITDSMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLEADLVQIQSEVEDTVQEARNAEDKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADIAESQVNKLRAKSR--------DSGKG----KEAAE-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8A569-1", "uniprot_id": "B8A569_DANRE", "id": "B8A569-1", "name": "", "aln": "-------------------------------------------MSTDAEMAVYGKAAIYLRKPEKERIEA--------------QNKPFDAKTACYVVDDKELYVKGTIKSRD-GGKVTVITLDTKEERVAKEDDVHPMNPPKFDKIEDMAMMTHLNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKK------------RMEAPPHIFSVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGPE-----------------------------------------KKKEQAAGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTSGKLASADIETYLLEKSRVTFQLPDERGYHIFYQMMT-NHKPELIEMTLITTNPYDFPMCSQGQI-TVASIDDKEELVATDTAIDILGFNAEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEEADKIAYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYERMFLWMVIRINQMLD-TKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKCNAFQKPKP-AKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNESVVQLYQKSSVKLLATLYPP-------------------------------------------------VVEETGG-----GKKGG-KKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRAYLMRREFVKMMERRESIYTIQYNIRSFMNVKH-WPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEALAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAAQDESIGKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKLKKKDFETSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTLEDQLSEIKSKNDENIRQINDLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-SKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQLGETGKSIHELEKSKKAVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRVTESMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLEADLVQIQSEVEDTVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEITVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELETEIEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADIAESQVNKLRAKSR--------DAGKG----KESAE-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2BGX6-1", "uniprot_id": "A2BGX6_DANRE", "id": "A2BGX6-1", "name": "", "aln": "-------------------------------------------MSTDAEMAVYGKAAIYLRKPEKERIEA--------------QNKPFDAKSACYVVDDKELYVKGTIKSKD-GGKVTVITLDTKEERVVKEDDVHPMNPPKYDKIEDMAMMTHLNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKK------------RMEAPPHIFSVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGGD-----------------------------------------KKKEQAPGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLPDERGYHIFYQMMT-NHKPELIEMTLITTNPYDFPMCSQGQI-TVASIDDKEELMATDSAIDILGFTGEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEEADKISYLLGLNSAELLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYEKMFLWMVIRINQMLD-TKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDVSFKNKLYDQHLGKCNAFQKPRP-QKGKAEAHFSLVHYAGTVDYNVNGWLDKNKDPLNESVVQLYQKSSVKLLATLYPP-------------------------------------------------VVEETGG-----GKKGG-KKKGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLATLVTMTQALCRAYLMRREFVKMMERRESIYTIQYNIRSFMNVKH-WPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEDLVKAEAKKKELEEKMVALLQEKNDLQLAVASEAENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKIKKKDFETAQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTVEDQLSEIKSKNDENLRQINDLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-SKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQIGETGKSIHELEKAKKTVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKGEIDRKLAEKDEEIEQIKRNSQRVTEAMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLESDLVQIQGEVEDTVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEITVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNINRLQDLVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADISESQVNKLRAKSR--------DAGKA----KEE---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PJW6-1", "uniprot_id": "A0A8M9PJW6_DANRE", "id": "A0A8M9PJW6-1", "name": "", "aln": "--------------------------------------------MGDGEMECFGPAAIYLRKTERERIEA--------------QNTPFDAKTAYFVVDADEMYLKGTLQSKE-GGKATVKTHSGKT-VTVKEDEIFPMNPPKFDKIEDMAMMTHLNEPCVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDAIVVAGYRGKK------------RIEAPPHIFSISDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVGAMSGA-----------------------------------------KKQEPVAGKMQGSLEDQIVAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLSAERSYHIFYQLMT-GHKPELLEALLITTNPYDYPMISQGEI-TVKSINDVEEFIATDTAIDILGFTADEKIAIYKLTGAVMHHGSMKFKQKQREEQAEPDGTEVADKIAYLMGLNSADMLKALCYPRVKVGNEMVTKGQTVPQVNNAVSALCKSVYEKMFLWMVIRINEMLD-TKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLHDQHLGKCSAFQKPKP-AKGKAEAHFSLVHYAGTVDYNIVGWLDKNKDPLNDSVVQLYQKSSLKVLAFLYASH-----------------------------------------------GGEAEGGG-----GKKGG-KKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRGYVMRKEFVKMMERREAIYSIQYNIRSFMNVKH-WPWMKLYFKIKPLLKSAETEKEMAAMKENYEKMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVASEGENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKSKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKIKKKDFEISQFLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERL--EEAGGATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTLEDQLSEIKTKSDENIRQLNDMNAQRARLQTENGEFSRQLEEKEALVSQLTRGKQAYTQQIEELKRHVEEEVKAKNALAHAVQSARHDCDLLREQFEEEQE-AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE-SKKKLAQRLQDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTEIFKMKNSYEEALDQLETLKRENKNLQQEISDLTEQLGETGKSIHELEKAKKTVESEKVEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRVLDAMQSTLDSEVRSRNDALRVKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERRNNLMQAEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLINTKKKLEADLVQIQGEVDDAVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVTRLQDLVDKLQLKVKAYKRQAEEAEEQANTHLSRYRKVQHEMEEAQERADIAESQVNKLRAKSR--------DAGKS----KDEE--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QVX3-1", "uniprot_id": "F1QVX3_DANRE", "id": "F1QVX3-1", "name": "", "aln": "-------------------------------------------MSGDPEMECFGPAAVYLRKPEKERIEA--------------QNRPFDAKTAYFVSEPKEMYLKGVLKSKE-GGKATVQTLCGKT-LTVKEDEIFPMNPPKFDKIEDMAMMTHLNEPTVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDAVVVSGYRGKK------------RIEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI-AVAGK-----------------------------------------QKQEPIPGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLSAERSYHIFYQLCT-GHKPELLEALLITTNPYDYPMISQGEI-TVKSINDVEEFIATDTAIDILGFNAEEKVGIYKLTGAVMHHGNMKFKQKQREEQAEPDGTEVADKIAYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVNNATMALCKSVYEKMFLWMVVRINEMLD-TKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTTFKNKLHDQHLGKTNCFQKPKP-AKGKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNDSVVQLYQKSSVKLLCHLYAAH-----------------------------------------------ASTEAESG-----GKKGG-KKKGGSFQTVSALFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASVIPEGQFIDNKKA-----SEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLVILVTMTQAVCRGYVMRKEFVKMMARRESIYSIQYNIRSFMNVKH-WPWMKLYFKIKPLLKSAETEKEMAAMKENFEKMKEDLAKALAKKKELEEKMVTLLQEKNDLQLQVASETENLSDAEERCEGLIKSKIQLEAKLKEATERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMTSQDEVIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESLMDLENDKQQLEEKLKKKDFETSQFLSRIEDEQSLGIQFQKKIKELQARIEELEEEIEAERAARAKVEKQRSDLARELEEISERL--EEAGGATSAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEVDDVSSSMEAVAKSKTNLEKMCRTLEDQLSEFKSKHDEHVRHINDLSAQKARLQTENGEMGRQLEEKESLVSQLTRSKQAYTQQIEELKRQIEEEVKAKNSLAHAVQSSRHDCDLLREQYEEEQE-AKAELQRSMSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQDAEESIEAVNAKCASLEKTKQRLQNEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEETQAELEGAQKEARSLSTELFKMKNSYEETLDHLETLKRENKNLQQEITDLTEQLGETGKTIHELEKGKKTAEIEKSEIQAALEEAEATLEHEESKILRVQLELNQVKGEIDRKLAEKDEEIEQIKRNSQRIIDSMQSTLDAEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQGQLKDAQLHLDEALRAQEDMKEQVAMVERRNNLMQAEIEELRVALEQTERGRKVAEQELVDASERVTLLHSQNTSLINTKKKLEADLVQIQGEMEDVVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAESLAMKGGKKQLQKLEARVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNIIRLQDLVDKLQLKVKAYKRQSEDAEEQANTHLTRFRKVQHELEEAQERADIAESQVNKLRAKSR--------EFGKG----KEAEE-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B1AR69-1", "uniprot_id": "B1AR69_MOUSE", "id": "B1AR69-1", "name": "", "aln": "-------------------------------------------MSSDAEMAIFGEAAPYLRKPEKERIEA--------------QNRPFDSKKACFAVDDKEMYVKGMIQSRE-NDKVIVKTLDDRE-LTLNSDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGD------------------------------------------KKKEQQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS-NKKPELIDLLLISTNPFDFPFVSQGEV-TVASIDDSEELLATDNAIDILGFSPEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP-TKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNY-----------------------------------------------AGAEAGDS---AGGKKGG-KKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA-----SEKLLNSIDVDREQFRFGHTKVFFKAGLLGLLEEMRDEKLVTLMTRTQAVCRGYLMRVEFKKMMERRESIFCIQYNVRSFMNVKH-WPWMNLFFKIKPLLKSAEAEKEMATMKEDFERAKEDLARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIQLEAKVKELNERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEETISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINVKLEQQTDDLEGSLEQEKKLRADLERVKRKLEGDLKMSQESIMDLENDTQQLEEKLKKKEFEMSQLQTRIDDEQVLSLQLQKKIKELQARTEELEEEIEAEHTVRAKIEKQRSDLARELEEISERL--EEASGATSAQIEMNKKRESEFQKLRRDLEEATLQHEATAATLRKKHADTVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIETVSKSKSNMERMCRSVEDQFNEIKAKDDQQTQLIHDLNMQKARLQTQNGELSHQVEEKESLVSQLTKSKQALTQQLEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEENTEASNSKCASLEKTKQRLQGEVDDLMLDLERANTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEIFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEVEKTKKQVEQEKSDLQAALEEVEGSLEHEESKILRVQLELSQVKSELDRKVTEKDEEIEQIKRNSQRAVEAMQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLSHANRQVAETQKHLRTVQGQLKDSQLHLDDAQRSNEDLKEQLAIVERRNGLLQEELEEMKVALEQTERTRRLSEQELLDSSDRVQLLHSQNTSLINTKKKLEADLAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELESELDAEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAEERADIAESQVNKLRAKSR--------DVGGQ---KMEE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFM0-1", "uniprot_id": "A0A8I6AFM0_RAT", "id": "A0A8I6AFM0-1", "name": "", "aln": "-------------------------------------------MSTDAEMAIFGEAAPYLRKPEKERIEA--------------QNRPFDSKKACFAVDDKEMYVKGMIQSRE-NDKVIVKTLDDRE-LTLNSDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGE------------------------------------------KKKEQQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS-NKKPELIDLLLISTNPFDFPFVSQGEV-TVASIDDSEELLATDNAIDILGFSPEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP-AKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNY-----------------------------------------------AGAEAGDS---TGGKKGG-KKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA-----SEKLLNSIDVDREQFRFGHTKVFFKAGLLGLLEEMRDEKLVTLMTRTQAVCRGYLMRVEFKKMMERREAIFCIQYNVRSFMNVKH-WPWMNLFFKIKPLLKSAEAEKEMATMKEDFERAKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIQLEAKVKELNERLEEEEETNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEETISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLMKINVKLEQQTDDLEGSLEQEKKLRADLERVKRKLEGDLKMSQESIMDLENDAQQLEEKLKKKEFEMSQLQTRIDDEQILSLQLQKKIKELQARTEELEEEIEAEHTVRAKIEKQRSDLARELEEISERL--EEASGATSAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADTVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEAVSKSKSNMERMCRSVEDQFNEIKAKDDQQTQLIHDLNMQKARLQTQNGELNHQVEEKESLVSQLTKSKQALTQQLEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE-GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEENTEASNSKCASLEKTKQRLQGEVDDLMLDLEKANTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEIFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEVEKTKKQMEQEKSDLQAALEEVEGSLEHEESKILRVQLELSQVKSELDRKVTEKDEEIEQIKRNSQRAVEAMQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLSHANRQVAETQKHLRTVQGQLKDSQLHLDDAQRSNEDLKEQLAIVERRNGLLQEELEEMKVALEQTERTRRLSEQELLDSSDRVQLLHSQNTSLINTKKKLEADLAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELESELDAEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAEERADIAESQVNKLRAKSR--------DVGGQ---KMEE---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKX3-1", "uniprot_id": "MYH13_HUMAN", "id": "Q9UKX3-1", "name": "Myosin-13", "aln": "-------------------------------------------MSSDAEMAIFGEAAPYLRKPEKERIEA--------------QNRPFDSKKACFVADNKEMYVKGMIQTRE-NDKVIVKTLDDRM-LTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGD------------------------------------------KKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS-NKKPELIDLLLISTNPFDFPFVSQGEV-TVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP-AKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNY-----------------------------------------------AGAETGDS---GGSKKGG-KKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA-----SEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKH-WPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERL--EEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQE-AKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE-AKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR--------DVGSQ---KMEE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AQP0-1", "uniprot_id": "MYH7B_MOUSE", "id": "A2AQP0-1", "name": "Myosin-7B", "aln": "----------------------------------------------MMDMSELGESACYLRQGYQEMMKV--------------HTVPWDGKKRVWVPDEQDAYVEAEVKTEATGGKVTVETKDQKV-LTVRETEMQPMNPPRFDLLEDMAMMTHLNEAAVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTAAVVAAYKGKR------------RSEAPPHIYAVADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPG---------------------------------------KKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDSYLLEKSRVIFQLPGERGYHVYYQILS-GKKPELQDMLLLSMNPYDYHFCSQGVT-TVDNMDDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHSGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENY-----------------------------------------------AGSCSTEP--PKSGVKEK-RKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDSFLVLHQLRCNGVLEGIRICRQGFPNRLLYADFRQRYRILNPSAIPDDTFVDSRKA-----TEKLLGSLDIDHTQYQFGHTKVFFKAGLLGILEELRDQRLAKVLTLLQARSRGRLMRLEYQRMLGGRDALFTIQWNIRAFNAVKN-WSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEAKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDEAVVRLTKEKKALQEAHQQALGDLQAEEDRVSALAKAKIRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVTDTTQDKQQLEEKLKKKDSELSQLNLRVEDEQLVGVQLQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL--EEAGGASAGQREGCRKREAELGRLRRELEEAVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKEKSELRMEVDDLGASVETLARGKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTENGELGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEESKAKGALAHAVQALRHDCDLLREQHEEESE-AQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEE-AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQREARGLGTELFRLRHSHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKAKKALEGEKSELQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECTNLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAMEAQAATRLLQAQLKEEQAGRDEEQRLAAELREQGQALERRAALLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEVDLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELVYQTEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQASTNLAKYRKAQHELDDAEERADMAETQANKLRARSR--------DALGP--KHKE----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F0L5-1", "uniprot_id": "F7F0L5_RAT", "id": "F7F0L5-1", "name": "Myosin-7B", "aln": "----------------------------------------------MMDMNELGESACYLRQGYQEMMKV--------------HTVPWDGKKRVWVPDEQDAYVEAEVKTEATGGRVTVETKDQKV-LTVRETEMQPMNPPRFDLLEDMAMMTHLNEAAVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTATVVAAYKGKR------------RSEAPPHIYAVADNAYNDMLRSKSHLPHRPSAQGGFRQREPVH--------------------------------------------------------ADHQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDSYLLEKSRVIFQLPGERGYHVYYQILS-GKKPELQDMLLLSMNPYDYHFCSQGVT-TVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHSGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENY-----------------------------------------------AGSCSTEP--PKSGVKEK-RKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDSFLVLHQLRCNGVLEGIRICRQGFPNRLLYADFRQRYRILNPSAIPDDTFVDSRKA-----TEKLLGSLDIDHTQYQFGHTKVFFKAGLLGILEELRDQRLAKVLTLLQARSRGRLMRLEYQRMLGGRDALFTIQWNIRAFNAVKN-WSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEAKVKELNERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVVRLTKEKKALQEAHQQALGDLQAEEDRVSALAKAKIRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVTDTTQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQLQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL--EEAGGASAGQREGCRKREAELGRLRRELEETVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKEKSELRMEVDDLGASVETLARGKASAEKLCRTYEDQLSEAKIKVEELQRQLTDASTQRGRLQTENGELGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEESKAKGALAHAVQALRHDCDLLREQHEEESE-AQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEE-AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQREARGLGTELFRLRHSHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKAKKALEGEKSELQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECTNLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAMEAQAATRLLQAQLKEEQAGRDEEQRLAAELREQGQALERRAALLASELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEVDLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQTEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQASTNLAKYRKAQHELDDAEERADMAETQANKLRARSR--------DALGP--KHKE----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7E2Y1-1", "uniprot_id": "MYH7B_HUMAN", "id": "A7E2Y1-1", "name": "Myosin-7B", "aln": "----MSGNKRGSRASCPHRGAECLLPWAALNLQGFQLLLLHPSATAMMDVSELGESARYLRQGYQEMTKV--------------HTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKV-LMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKR------------RSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPG---------------------------------------KKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILS-GRKPELQDMLLLSMNPYDYHFCSQGVI-TVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENY-----------------------------------------------AGSCSTEP--PKSGVKEK-RKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKA-----TEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKN-WSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL--EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAE-AQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEE-AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR--------DALGP--KHKE----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q264-1", "uniprot_id": "E9Q264_MOUSE", "id": "E9Q264-1", "name": "", "aln": "-----------------------------------------------MDLSEFGDATAFLRRNKADP-LF--------------QPPAFDGKKKCWVPDGKNAYIEAEVKESGDDGQVIVETRDGEI-MRIKEDKLQQMNPEELEMIEDLSMLLYLNEASVLHTLRRRYDHWMIYTYSGIFCVAINPYKWLPVYQKEVMAAYKRKR------------RSEVPPHIFAVANRAFQDMLRNGENQSIVFTGESGSGKTVNTKLIIQYFATMAAISEP------------------------------------------------KKKLGNLEDQIVKMNPLLEAFGNAKTQKNDNSSRFGKLIRIHFGARGTLSFADIQIYFLEKSRVVYQQPGERNYHIFYQILS-GNQ-ELRNMLLVSTNPSDFHICSCGVV-AVESLDDAKEFLATEKAIDVLGFLPDEKFGCYKLVGAIMHFGNLKFKRNLREEQLEADGTENADKAAFLMGIHASELLKGLIYPRIKVGNEYVTRSQNLQQVTYAVGALSQSIYERMFQWLVARMNQVLD-AKLTSHFFVGILDTTGFEILDYNSLEQLCINFTNEKLQQFFNQQLFILEQEEYRKEGLDWLSIDYGLDVQACIDFIEKPM---GIFSILEEECMLPKATDQMFKTKLFDHHFGKSAYFQTPTS-PEKNFEVHFELAHYAGVVPYNISGWIGKNKGLLNETVVALLQKSSNKVLANLFTK---------------------------------------------------DIIAGSASQFGEKTH--KKGTSFHLITSLHKENINKLMTDLKSTAPHFVRCINPNKNKIPGVMDPFLVLQQLRCNGVLEGIRVCCEAFPSWMLYDDFKQRYWILNPRIFSKSKFVSSRKA-----TEEVLDFLEIDHPHYQCGVTKVFFKAFILDQLEERRDEKISKVFTLFQARARGKLMRITFQKILEERDALALIQENIRAFIAVKN-CPWMGLFFKIKPLAKSVGAGEEIAGLKEECAQLQKALESSESQREELKTKQVSLVQEKNDLRLQLQAEQETLANSEEQCESLIKSKVELEVKIKELSRQVEEEEEINSELTARGRKLEDECSELKKEIYDLEAILAKSEKGKCAAEHKVRNLTEEVHSLNEEVSKLSRVVKDAQETQQQTQEQLHIEEEKLSNMSKANLKLAQQIDVLEGDLERERKARMKCEREKRKLQDELKMNQEGAENLESSRQKLAEQLRKKEFEMGQMNSKVENEKNQVSQLQKMVKELQTHILNLKEELESERTIRAKVEREKGDLVQDLEDLNERL--EEAGGTSLAQMEITKQQEARFQKLHHDMEETTRHFEATSASLKKRHAENLAELEGQVEHLQQVRLVLEQDKSDLQLQVDDLLNRVDQMARAKANAEKLCGLYERRLNEANTKLDEVTQLAHDLTTQKTKLQSESGEFFKRLEEKEALISQLSREKSNFTRQVEELRAQLEEESRSQSALSHALQSAKHDYDLLREQYEEEQE-VKAELHRALSKGNKETVQWRAKYEHDAMQRTEDLEE-AKKKLAIRLQEAAEAMEVSNAKNASLERARHRLQLELGDALSDLGKARSVAAALGQKQQHSDKALTSWKQKLDETQELLQASQKETRALSSEVLTFRQACEESTEAQETLKRQNQDLQEQICSLTNQVREGIKNLAEVEKAKKLIEQEKTEVQVRLEETEGALERNESKILRFQLELSEAKAELERKLSEKEEEAERLREKHQQAMGSLQSNLDLEASSRIEATRLRKKMEGDLKEMEIQLCAANRQVSQMTRALGQLQGQMKDLHQQLDDSIYQNKDLKEQVALAEQRTVLLQSELEELRTLQEQTERGRKLAEKELLEATERINLFHTQNTSLLSQKKKLEADVAQVQKEAGEMLQACQKAEEKAKKTAAEAANMSEELKKEQDTNAHLERMRKNMEQTIKDLQKRLDEAEQTAVLGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELTYQAEEDKKNLSRMQALSDKLQLKVQSYKQQVEAAEAQANQYLSKYKKQQHELNEAKERAEAAESQVNKLRAKAK--------ELEKK--VREE----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JY53-1", "uniprot_id": "A0A0G2JY53_RAT", "id": "A0A0G2JY53-1", "name": "", "aln": "----------------------------------------------MMDLSEFGDAAAFLRRNRAEP-WF--------------QPPAFDGKKKCWVPDGKNAYTEAEVKESSGDGHVIVETRDGES-LRIREDEIQQMNPAELEMIEDLSMLLYINEGSVLHTLRKRYDHWMIYTYSGLFCVAINPYKWLPVYQKEVMAAYKRKR------------RSEAPPHIFAVANHAFQDMLRNGENQSILFTGESGSGKTVNTKMIIQYFATMAATSEP------------------------------------------------KKKLGNLEDQIVQMNPILEAFGNAKTLRNDNSSRFGKFIRMYFGVRGTLSFADIQIYFLEKSRVVYQQPGERNYHIFYQILS-GKQ-ELQDMLLVSTNPSDFHICSCGVV-AVENLDDAKGFLATEKAIDVLGFLPDEKFGCYKLVGAIMHFGNLKFRQNPREEQLEADGTENADKAALLMGINASELLKGLIYPRIKVGNEYVTRSQNIQQVTYAVGALSKSIYERMFKWLVARMNQVLD-AKVTSHFFIGILDITGFEILDYNSLEQLCINFTNEKLQQFFNQQLFVLEQEECRKEGLDWMSIDYGLDLQACIDLIEKPM---GILSILEEECMLPKATDNTFKTKLFAHHFGKSAYFQKPTA-PEKNFEVHFELAHYAGVVPYDISGWIGKNKELLNETVVALLQKSSNKVLASLFTN---------------------------------------------------NTIAG---SFGEKPR--RKATSFQLITSLHKESINKLMADLKSTAPHFVRCINPNENKIPGVMDPFWVLQQLRCNGVLEGTRVCCKAFPIRMLYDDFKQRYCILNPRIFSKSKFVNIRKA-----TEEVLALLEIDQSQYQCGVTKVFFKARILDRLEERRDEKISKVFTLFQARARGKLMRITFQKILEERDALALIQENIRAFIAVKT-WPWMGLFFKVKPLAKSVGAGEEIAGLKEECAQLQKSLETSESQREELKTKQVSLVQERNDLLLQLQAEQETLANSEELCESLIKSKIELEAKIKELSRRVEEEEEINSELTARGRKLEDECSELKKEIYDLEAILAKSEKAKCAAEHKVRNLTEEVHSLHEDVSKLTRAMQAAQEAQQQTQEHLHIEEEKLSNVSKVNQKLSQQVDALEGDLERERKARMKCEREKHKLEGELKLNQEGAENLESSRQQLIEQLRKKEFEMGQMNSKVENEKNLVSQLQKTVKELQTQILNLKEELESERTIRAKVERERGDLAQDLEDLNERL--EEAGGTSLAQMEITRQQEARFQKLRHDMEETTRHFEATSVSLKRRHAENVAELEGQVEHLQQVRQVLDQEKSDLQLQVDDLLTRVDQMARAKANAEKLCGLYERRLNEANTKLDEATQLAKDLTSQRTKLQNESGEFFKRLEEKEALISQLSREKSNLILQVEELRVQLEEESKSQSALAHALQSTKHDYDLLREQYEEEQE-VKSELHRALSKGNKETVQWRTKYEHDAMQRTEDLEE-AKKKLAIRLQEAAEAMEVSNAKNASLERARHRLQLELGDALSDLGKARSVAAALGQKQQHSDKALASWKQKQEEAQELLQASQKEARALSSEVLMLRQACEESNEAQETLKRQNQDLQERICCLTNQVREGIKNLTEVEKAKKLIEQEKTEIQARLEEAEGALERNESKILRFQLDLSEAKAELGRKLSEKEDEAGRLREKHQQALGSLQSSLDSEASSRIEATKMRKKIEGDLKEMEIQLCTANRQVSQTTRALGQLQSQMKDLQQHLDDSIYQNKDLKDQVALAEQRNILLQSELEELRSLQEQTERGRKLAEKELLEATERISLFHTQNASLLSQKKKLEADVAQAQKEAGEMLQACQKAEEKAKKTAAEAANMWEELKKEQDTNAHLERTRKNMEQTIKDLQKRLDEAEQTAVVGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELTYQAEEDKKNLSRMQALSDKLQLKVQSYKQQVEAVEAQANQYLSKYKKQQHELNEAKERAEAAESQVNKLRARAK--------ELERK--VREEGVSFH-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K3-1", "uniprot_id": "MYH15_HUMAN", "id": "Q9Y2K3-1", "name": "Myosin-15", "aln": "-----------------------------------------------MDLSDLGEAAAFLRRSEAELLLL--------------QATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGES-LSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR------------RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIES------------------------------------------------RKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILS-GQK-ELHDLLLVSANPSDFHFCSCGAV-TVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALD-AKLSRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP-DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFEN---------------------------------------------------YMSTDSAIPFGEKKR--KKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA-----AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKN-WPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERL--EEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQE-VKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLED-AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR--------EFGKK--VQEE----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05661-3", "uniprot_id": "MYSA_DROME", "id": "P05661-3", "name": "Myosin heavy chain, muscle", "aln": "-------------------------------------------MPKPVANQEDEDPTPYLFVSLEQRRID--------------QSKPYDSKKSCWIPDEKEGYLLGEIKATK-GDIVSVGLQGGET-RDLKKDLLQQVNPPKYEKAEDMSNLTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKR------------RNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGASKKT---------------------------------------------DEAAKSKGSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKARVISQQSLERSYHIFYQIMS-GSVPGVKDICLLTDNIYDYHIVSQGKV-TVASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETLD-TQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKREGIDWAFIDFGMDLLACIDLIEKPM---GILSILEEESMFPKATDQTFSEKLTNTHLGKSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLIEIFADH-----------------------------------------------AGQSGGGE-----QAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLLQG--VEKDKKA-----TEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARGYLSRKGFKKLQEQRVALKVVQRNLRKYLQLRT-WPWYKLWQKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELGERL--EEAGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDNLREQVEEEAE-GKADLQRQLSKANAEAQVWRSKYESDGVARSEELEE-AKRKLQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFRAKGR--------AGSVGRGASPAPRATSVRPQFDGLAFPPRFDLAPENEF-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O08638-1", "uniprot_id": "MYH11_MOUSE", "id": "O08638-1", "name": "Myosin-11", "aln": "----------------------------------------------MAQKGQLSDDEKFLFVDKNFMNSP-------------MAQADWVAKKLVWVPSEKQGFEAASIKEEK-GDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKYLPIYSEKIVDMYKGKK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTQKVIQYLAVVASSHK----GKKDSSIT-----------------------------------------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLA-GAKEKMKSDLLLESFN-SYTFLSNGFV-PIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPSIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCSEQ-GNHPKFQKPKQ---LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD-----------------------------------------VDRIVGLDQMAKMT----ESSLPSASKTKKGMFRTVGQLYKEQLGKLMATLRNTTANFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQA-----CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQLQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL--EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEME-AKQNLERHVSTLNIQLSDSKKKLQ-DFASTIEVMEE-GKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEESEDDVQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNEAMGREVNALKSKLR--------RGNEASFVPS--RRAGG------RRVIENTDGSEE----------EMDARDSDFNGT-------KASE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63862-1", "uniprot_id": "MYH11_RAT", "id": "Q63862-1", "name": "Myosin-11", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK----GKKDSSITQ----------------------------------GPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRHARDERTFHIFYYLIA-GAKEKMRNDLLLESFN-SYTFLSNGFV-PIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCSEQ-GNHPKFQKPKQ---LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD-----------------------------------------VDRIVGLDQMAKMT----ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQA-----CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTASKVIQRNCAAYLKLRN-WQWWRLFTKVKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDEEME-AKQNLERHVSTLNIQLSDSKKKLQ-DLASTIEVMEE-GKKRLQKEMEGLGQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEAELMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELVTERSAAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIVQLEEQIEQEAREKQAATKLLKQKDKKLKEVLLQVEDERKMVEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR--------RGNEASFVPS--RRAGG------RRVIENTDGSEE----------EMDARDSDFNGT-------KASE-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35749-1", "uniprot_id": "MYH11_HUMAN", "id": "P35749-1", "name": "Myosin-11", "aln": "----------------------------------------------MAQKGQLSDDEKFLFVDKNFINSP-------------VAQADWAAKRLVWVPSEKQGFEAASIKEEK-GDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK----GKKDTSIT-----------------------------------------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIA-GAKEKMRSDLLLEGFN-NYTFLSNGFV-PIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQ---LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD-----------------------------------------VDRIVGLDQMAKMT----ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQA-----CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL--EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME-AKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEE-GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR--------RGNETSFVPS--RRSGG------RRVIENADGSEE----------ETDTRDADFNGT-------KASE-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFE6-1", "uniprot_id": "A0A8M9QFE6_DANRE", "id": "A0A8M9QFE6-1", "name": "", "aln": "----------------------------------------------MTKKG-LSDDEKFLFTDKDFINSP-------------VAQADWSAKKLVWVPSEKHGFESASIKEEH-GDEVLVELMDNGKKITVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVVNPYKMLPIYSEKIIEMYKGKK------------RHEVPPHIYSITDNAYRNMMQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK----GKKDMSAQQS---------------------------------GQQFAYGELEKQLLQANPILEAFGNAKTIKNDNSSRFGKFIRINFDVTGFIVGANIETYLLEKSRCIRQAKTERAFHIFYYMVA-GTKDKLREELLLENFN-NYRFLSAGHV-QIPGNQDDEMYDETMEAMEIMGFSVEERADVLKVVSTVLQLGNIEFKKERNQEQATMPDNTAAQKVCHLQGINVTDFTRAILTPRIKVGREVVQKAQTKEQADFAIEALAKAMYERLFRWILLRVNKALDKTKRQGASFLGILDIAGFEIFENNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGILALLDEECWFPKATDVSFVEKLCNTH-ANHTKFAKPKQ---LKDKTEFSVQHYAGRVDYNAVAWLTKNMDPLNDNVTALLNNSSNPFVQDLWKD-----------------------------------------ADRVVGLETIAKMS----DSLAPSASKTKKGMFRTVGQLYKESLAKLMTTLHNTQPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQA-----CCLMIKHLDIDPNLYRIGQSKIFFRTGVLAQLEEERDLKITVIIIAFQSQARGFLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMSLKEEELQKAKESAQKFEIELKDIALKHTQLMDERNQLQEKLQAETELYAEAEEMRVRLASKKQELEEILHEMEARLEEEEDRGAALQMEKKKMHEQIKDLEEHLEEEEDARQKLQLEKVTCDAKIKKLEDDILIMDDQNNKLQKERKILEERIADFSSNLAEEEEKSKNLTKLKNKHESMISELEVRLKKEEKTRQELDKAKRKLEAESNDLQEQIADLQAQIADLKAQLAKKEEELQAALARLEDETGQKNNALKKIRELEGHISDLQEDLESERAARNKAEKTKRDLGEELEALKSEL--EDTLDTTATQQELRAKREQEVTLLKRAIEDESRVHEAQVQEMRQKHTQTLEELTEQLEQSKRVKVNLEKAKQALEKETSELHVELRSLTQGKQDVEHKKKKLEGQLADLQSRFNDSERHKAELGDRVSKITVELESVTNLLNEAEGKNIKLSKDVASLSSQVQDTQELLAEETRQKLQLSTKLRQIEDDRNALQEQLDEEAE-AKRNVERHVSTLNIQLSDFKKKLE-EMTGNVELLEE-GKKRLQRDLEAANTQFEEKAAAYDKLEKTKNRLQQELEDTLMDLDNQRQLVSNLEKKQKKFDQMLAEEKSISSKYADERDRAEAEAREKETKALSLARALEEAQEAREEFERANKALRAEMEDLVSSKDDVGKNVHELEKSKRGLEAQVEEMKTQLEELEDELQAAEDAKLRLEVNMQALKAQFERDLQGRDEQGEEKKRQLVKQVRELETELEDERKQRTALAASKKKLEGDLKDLEGQIETSNKGRDEAIKQLRKLQAQMKDFQRELDDAHAAREEVLSSAKENERKAKTLEAELLQLQEDLAAAERAKKQVEAERDELADELASNASGKSALSDEKRRLEAKIQQLEEELEEEQGNMEMLNDRLRKSAQQVDQLTNELQAERTTSQKNESARQLMERQNKELKAKLQEMENQVKSKFKSSISALEAKVAQLEEQLEQESRDKQNTAKAVRQKDKKLKEMMTQVEDERKQAEQYKDQADKATARVKQLKRQLEESEEESQRITAARRKLQRELDEATETNDAMSREVNSLKSKLR--------RGNETSSFSSTPRRTGGGG---RRGIIDSSDAAED----------DADMQ-SDYNGT-------KSNE-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z539-1", "uniprot_id": "A0A8M6Z539_DANRE", "id": "A0A8M6Z539-1", "name": "", "aln": "----------------------------------------------MTMQD-NDDSNKFLFLDSEFKNSG-------------VAQADWSTRKMVWIPSERDGFQSASIKEET-GNEVVVELD-NGQKVTVSKDDIQKMNPPKFNKVEDMAALTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKMLPIYSEKIIEMYKGKK------------RHEVPPHIYSVTDNAYRNMLQEREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK----GKKEATSDTSSSA------------------------PNKQQKGSQLAFGELEKQLLQANPILEAFGNAKTIKNDNSSRFGKFIKINFDNTGYIVGANIETYLLEKSRCIRQAKIERSFHIFYYMVA-GAKDKMREELLLEDFA-NYRFLVAGHV-QVQNQQDDEMLEETLEAMEVLGFNEEERIGMFKICSTVLQLGNIEFKAEKNQEQASMPDNTAAQKVCHLQGINVTDFTKAMLTPKIKVGRELVQKAQTKEQADFAVEALAKAMYDRLFRWILGRVNKALDKTKRQGASFIGILDIAGFEIFEDNSFEQLCINYTNEKLQQLFNHTMFILEQEEYKKEGIEWSFIDFGLDLQPCIELIERPNNPPGILALLDEECWFPKATDVSFVEKLTNTH-SSHCKFSKPKN---LKEKTFFTVQHYAGKVDYNAMSWLTKNMDPLNDNVTALLSNSSSAFIQDIWKD-----------------------------------------VDRVVGLETMAKMAKS--DSSAPAASKSKKGMFRTVGQLYKESLGKLMTTLHNTQPNFVRCIIPNHEKRAGKIDAHLVLDQLSCNGVLEGIRICRQGFPNRIVFHEFRQRYEVLAAGSIPKG-FMDGKQS-----CTLMIKHLDLDPNLYRIGLSKIFFRTGVLAQLEEERDLKLTDIIIAFQAQARGFLGRKAFSNKQKQLTAMKVLQRNCAVYLTLRN-WQWWRLFTKVKPLLQVTRQEEEMNQIEEELQKAKEIAQKSETELKEITQKHDQVVEERNKLQAKLQEEAELYAESEEVRIRLETKKQELEEVLHEMEARLEEEEERSQAFQQEKGNLQQKLKELENHLAEQDATRQKLQLESGAADGKIKKLEEDVLIMEDQKNKLQKEKQQLEERLADFSSNLAEEEEKSKNLTKLKAKHESMISDLEVRMKKEEKSRQDVEKAKRKLETEHSDLQEQMKNLQTLIAELKTQQARSEMEIQELQASVEAESTQKSNALKKIHEMEGLLSELQDELEAEQGAGRKSEKARKELEEELSALRTEL--EDSLDTTAVQQELRAKREQEVAMLKKLIEDEGRSHEAQVHELKQKHAQAVDELSQQLDQSKRAKATLEKAKQALEKEVGDLNGNLRSLGNAKQDLEQKKKKVETQLADLQTRFNESERKREELGDAVSKLNTEYNNVNSILNEAESKNIKLSKDVVSLNSQLQDAQELLAEETRQKLNFSTRLRQMEDERNGLLEQIDEETE-ARRNVERHVSSLNTQLSEAKKRLD-EYSSNFQMLEE-SKKRLQRDLEATKGELEEKTASYDKSEKTKNHLQQELDDVLLDLDNQRQLVSNMEKKQRKFDQMLADEKTLSSKYSQERDCAEAEAREKETKCLALTRALEECQGSLRELEKLNKTLRTDMEDLISSKD--NKNAHELEKTKRALEAQVEEMTIQMEELEDELQAAEDAKLHLEVNMQALKVQIQRDIQGREEQSEEKRKQLLKQVRELEAELEDEQKMRTSLAAAKKKLEGDLQDLEDQVDVNSRARDEAVKQLRKIQTQMKDYQRELEDARASHKEVLSDARESERKARAMEAEILHLHEELASAEKARKHAERERDEIAGEMASGSFGKSGTSDEKRRLESKIQHLEEELDDEQATTETLNERLRRSVQEVDQLTNELHTERSNAQRMESGWQQMERQNKELRAKLLEMEGQVKSKQRSTVAALESKLQQTEDQLDHESRERQAIAKAMRQKDKKLKELMNQVEDERKQMEQYKDQAEKANLRARQLKMQMEESDEESQRATAARRKLQKELNEAIEANDALSREVSSLRSKLR--------RGSDSSFSTPLRRSAGGSFRQARRTMMETSEIPEDGGPSATSVCQPGELQMESISNT-------QDNN-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VDD5-1", "uniprot_id": "MYH9_MOUSE", "id": "Q8VDD5-1", "name": "Myosin-9", "aln": "--------------------------------------------------MAQQAADKYLYVDKNFINNP-------------LAQADWAAKKLVWVPSSKNGFEPASLKEEV-GEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK------------RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----SKKDQ--------------------------------------------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLS-GAGEHLKTDLLLEPYN-KYRFLSNGHV-TIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLGNIAFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQ-GTHPKFQKPKQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD-----------------------------------------VDRIIGLDQVAGMS----ETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQA-----CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRN-WQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL--EDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEE-AKRNLEKQIATLHAQVTDMKKKME-DGVGCLETAEE-AKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR--------RGDLPFVVTR---RIVRK------GTGDCSDEEVD-------------GKADGADAK-------AAE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62812-1", "uniprot_id": "MYH9_RAT", "id": "Q62812-1", "name": "Myosin-9", "aln": "--------------------------------------------------MAQQAADKYLYVDKNFINNP-------------LAQADCGAKKLVWVPSTKNGFEPASLKEEV-GEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVDMYKGKK------------RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----SKKDQ--------------------------------------------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLS-GAGEHLKTDLLLEPYN-KYRFLSNGHV-TIPGQQDKDMFQETMEAMRIMGIPEDEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQ-GTHPKFQKPKQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD-----------------------------------------VDRIIGLDQVAGMS----ETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVCCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQA-----CVLMIKALELDSNLYRIGQSKVFFRSGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLRLRN-WQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKTEL--EDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQVTDMKKKME-DGVGCLETAEE-AKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEALIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR--------RGDMPFVVTR---RIVRK------GTGDCSDEEVD-------------GKADGADAK-------ATE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35579-1", "uniprot_id": "MYH9_HUMAN", "id": "P35579-1", "name": "Myosin-9", "aln": "--------------------------------------------------MAQQAADKYLYVDKNFINNP-------------LAQADWAAKKLVWVPSDKSGFEPASLKEEV-GEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK------------RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHK----SKKDQ--------------------------------------------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLS-GAGEHLKTDLLLEPYN-KYRFLSNGHV-TIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQKPKQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD-----------------------------------------VDRIIGLDQVAGMS----ETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQA-----CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRN-WQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL--EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE-AKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEE-VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR--------RGDLPFVVPR---RMARK------GAGDGSDEEVD-------------GKADGAEAK-------PAE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEM1-1", "uniprot_id": "A0A8M1NEM1_DANRE", "id": "A0A8M1NEM1-1", "name": "Myosin-9", "aln": "----------------------------------------------------MSDAEKFLYADRNTINDP-------------LAQADWATKKLVWVPSEKLGFEAGSIKEET-GDECLVELADSGKKIKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKYLPIYTEEIVEMYKGKK------------RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSFK----TKKDQSSIAL-------------------------------------SHGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKDERAFHIFYYLLT-GAGDKLRSELCLEDYN-KYRFLSNGNV-TIPGQQDRELFAETIDAFRIMGIPEDEQTGLLKVVSAVLQLGNMSFKKERNSDQASMPDDTAAQKVSHLLGMNVTDFTRAILSPRIKVGRDFVQKAQTQEQAEFAVEALAKATYERLFRWLVMRINKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIELIEKPNGPPGILALLDEECWFPKATDKSFVEKVVQEL-GNNPKFQKPKK---LKDDADFCIIHYAGKVDYKANEWLMKNMDPLNDNVATLLNQSVDKFVSELWKD-----------------------------------------VDRIVGLDKVAGMG----ES-LHGAVKTRKGMFRTVGQLYKEQLMNLMTTLRNTNPNFVRCIIPNHEKKAGKLAHHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA-----CVLMVKALELDSNLYRIGQSKVFFRAGVLAHLEEERDMKITDVIINFQAWCRGYVARRAFAKRQQQLTAMRVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMVAKEEELVKMKERQQQAEDQLKESEAKQKQLNAEKLALQEQLQAETELCQEAEEMRSRLTARMQEMEEVLHELESRLEEEEERVAQFQSEKKKMQQNIGDLEQQLDEEEAARQKLQLEKVTMDAKLKKIEEDLMVIEDQNAKLSKEKKQMEERISEFTTNLAEEEEKSKSLQKLKTKHETMITDLEDRLRKEEKMRQELEKNRRKLEGDSTELHDQIAELQAQIAELRAQLAKKEEELQAALARIEEEAALKNAAQKSIREMEAQISELQEDLELEKAARNKAEKQRRDLGEELEALKTEL--EDTLDSTAAQQELRAKRETEVTQLKKTLEDEARAHEQMLSEVRQKHNQAFEELNEQLEQSKRSKASVDKAKQALESERNELQIELKSLSQSKNDSENRRKKAESQLQELQVKHTESERQKHELLDKVSKMQAELESLQGTVTKVESKSIKAAKDCSAVESQLKDAQALLEEETRQKLAISTRLRQLEDEQNNLKEMLEEEEE-SKKNVEKQLHTAQAQLAEMKKKIE-QEAQSLESMED-GKKKLQREVESVLQQLEERNASYDKLDKTKTRLQRELDDVLVDQGHLRQTVQELERKQKKFDQMLAEEKSISTKYAEERDRAEAEAREKETKSLTLARELEAMTDLKNELERVNKQLKTEMEDLVSSKDDAGKSVHELERAKRGMEQQLEEMKTQLEELEDELQLTEDAKLRLEVNMQALKAQFERDLQSRDEQGEEKRKQLVKQVREMEMELEDERKQRAQAVSVRKKLELDLSELAAQIDLANKARDEALKQLKKLQAQMKEQMREFEDLRLSRDESLNQAKENERKIKSMEAEIMQLHEDLAAADRAKRQIQQERDELQDEINSQNAKNSLSSDERRRLEARIAQLEEELEEEHLSVELVNDRLKKASLQAEQVTVELTAERSNSQRLEGLRSQLDRQNKDMKQKLQELEGAVKSKYKSTITALETKIQQLEEQLDSEMKERQQSTKQVRRVEKKLKEVLLQVEDERRNADQSKTETEKANIRLKQMKRQLEETEEEAARANASCRKLRRELEDATESASAMNREVSTLKNKLR--------RGDFTGNVRR---AIGRT------GVE--SDDEND-------------LKSEGSEPT-------PE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61879-1", "uniprot_id": "MYH10_MOUSE", "id": "Q61879-1", "name": "Myosin-10", "aln": "----------------------------------------------MAQRTGLEDPERYLFVDRAVIYNP-------------ATQADWTAKKLVWIPSERHGFEAASIKEER-GDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----GRKDHN-----------------------------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLS-GAGEHLKSDLLLEGFN-NYRFLSNGYI-PIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD-----------------------------------------VDRIVGLDQVTGMT----ETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA-----CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRH-WQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL--EDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEE-ARKNLEKQVLALQSQLADTKKKVD-DDLGTIESLEE-AKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR--------RGGPISFSSS---RSGRRQLHIEGASLELSDDDTE-------------SKTSDVNDT-------QPPQSE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JLT0-1", "uniprot_id": "MYH10_RAT", "id": "Q9JLT0-1", "name": "Myosin-10", "aln": "----------------------------------------------MAQRTGLEDPERYLFVDRAVIYNP-------------ATQADWTAKKLVWIPSERHGFEAASIKEER-GDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEKPPHIYAISESAYRCMLQDRKDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----GRKDHN-----------------------------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLS-GAGEHLKSDLLLEGFN-NYRFLSNGYI-PIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGTSFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD-----------------------------------------VDRIVGLDQVTGMT----ETAFGSAYKTKKGMFRNVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA-----CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRH-WQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEGEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL--EDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEE-ARKNLEKQVLALQSQLADTKKKVD-DDLGTIEGLEE-AKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR--------RGGPISFSSS---RSGRRQLHIEGASLELSDDDTE-------------SKTSDVNET-------QPPQSE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35580-1", "uniprot_id": "MYH10_HUMAN", "id": "P35580-1", "name": "Myosin-10", "aln": "----------------------------------------------MAQRTGLEDPERYLFVDRAVIYNP-------------ATQADWTAKKLVWIPSERHGFEAASIKEER-GDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----GRKDHN-----------------------------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLS-GAGEHLKSDLLLEGFN-NYRFLSNGYI-PIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQ---LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD-----------------------------------------VDRIVGLDQVTGMT----ETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA-----CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRH-WQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL--EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEE-ARKNLEKQVLALQSQLADTKKKVD-DDLGTIESLEE-AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR--------RGGPISFSSS---RSGRRQLHLEGASLELSDDDTE-------------SKTSDVNET-------QPPQSE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7USR7-1", "uniprot_id": "A0A8N7USR7_DANRE", "id": "A0A8N7USR7-1", "name": "", "aln": "-------------------------------------------MPEMAQRSGQEDPERYLFVDRAVVYNP-------------TTQADWTAKKLVWVPSERHGFEAASIREER-GEEVLVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK------------RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK----GRKDHN-----------------------------------------IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHVFYQLLA-GAGEHLRSDLLLEGFN-SYRFLSNGNI-PIPGQQDKDNFQETMEAMHIMSFNHEEILSMLKVVSAVLQFGNIVFKKERNTDQASMPENTAAQKLCHLLGMNVMEFTRAILSPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVDKLVQEQ-GTHGKFQKPRQ---LKDKADFCIIHYAGRVDYKADEWLMKNMDPLNDNVATLLHQSTDKFVAELWKD-----------------------------------------VDRIVGLDQVAGMN----ETAFGAAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLEPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA-----CERMIRALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDIIIYFQSVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRH-WQWWRLFTKVKPLLQVTRQEEEMQAKDEELIKVKERQVKVENELVEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLVAKKQELEEILHDLESRVEEEEERNQSLQNEKKKMQSHIQDLEEQLDEEEAARQKLQLEKVTAEAKIKKMEEDILLLEDQNSKFLKEKKLLEDRVGEMTSQLAEEEEKAKNLGKVKNKQEMMMVDLEERLKKEEKTRQELEKAKRKLDAETTDLQDQIAELQAQIDELKIQLAKKEEELQAVLARGDEEVAQKNNALKQLRELQAQLAELQEDLESEKAARNKAEKLKRDLSEELEALKTEL--EDTLDTTAAQQELRSKREQEVAELKKAIDDETRNHESQIQEMRQRHGTALEEISEQLEQAKRVKGNLEKNKQTLESDNKELTNEVKSLQQAKSESEHKRKKLEAQLQEVMARFSEGEKVKGELADRTHKIQTELDNVSCLLEDAEKKGIKLTKDVSSLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNNLLEQQEEEEE-SRKNLEKQLATLQAQLVETKKKLE-DDVGALEGLEE-VKRKLQKDMEVTSQKLEEKAIAFDKLEKTKNRLQQELDDLMVDLDHQRQIVSNLEKKQKKFDQMLAEEKTISARYAEERDRAEAEAREKDTKALSMARALDEALEAKEEFERLNKQLRAEMEDLISSKDDVGKNVHELEKSKRTLEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFDRDLQARDEQNEEKKRALVKQVREMEAELEDERKQRALAVAAKKKLEMDLKDVEAQIEAANKARDEAIKQLRKLQAQMKDYQRELEEARTSRDEIFTQSKENEKKLKSLEAEILQLQEDLASSERARRHAEQERDELADEISNSASGKAALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTMQVDTLNTELAGERSAAQKSENARQQLERQNKDLKSKLQELEGSVKSKFKASIAALEAKILQLEEQLEQEAKERAAANKIVRRTEKKLKEVFMQVEDERRHADQYKEQMEKANSRMKQLKRQLEEAEEEATRANASRRKLQRELDDATEASEGLSREVNTLKNRLR--------RGGPVSFSSS---RSGRRQLQMEG---DFSDDDAD-------------SKASDLNEN-------QPPPAE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6URW6-1", "uniprot_id": "MYH14_MOUSE", "id": "Q6URW6-1", "name": "Myosin-14", "aln": "---------------------------------------MAAVTMSVSGRKVASRPGPVPEAAQSFLYAPRTPNVGG-PGG---PQVEWTARRMVWVPSELHGFEAAALRDEG-EEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLG-GAGEQLKADLLLEPCS-HYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GSHPKFQRPRN---LRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-----------------------------------------VEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA-----CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRN-WQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERTRLAEQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELESHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRLKYEATISDMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAALLRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGEL--EDTLDSTNAQQELRSKREQEVTELKKALEEESRAHEVSMQELRQRHSQALVEMAEQLEQARRGKGVWEKTRLSLEAEVSELKAELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARSEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVV-ARERAGRELQSTQAQLSEWRRRQE-EEAAVLEAGEE-ARRRAAREAETLTQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERIEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARKAAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQVQMKELWREVEETRSSRDEMFTLSRENEKKLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQNNSELLKDHYRKLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEEEAEGAE------------PGSAPGQEPE------APPPATPQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A9A3-1", "uniprot_id": "A0A8I6A9A3_RAT", "id": "A0A8I6A9A3-1", "name": "", "aln": "---------------------------------------MATVTLSVPGRKVASRPGPVPEAAQPFLFAPRTPNVGG-PGG---PQVEWTARRMVWVPSELHGFEAAALRDEG-EEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHIYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLG-GAGEQLKADLLLEPYS-HYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GSHPKFQRPRN---LRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEQGGLQQFTFLGSFPSPSPGPAGGLSSGASPPGLGSLCAPTVEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA-----CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRN-WQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELETHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRVKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMMEQKQRAEELLIQLGRKEEELQSALVRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGEL--EDTLDSTNAQQELRSKREQEVTELKKTLEEEARTHEVAMQELRQRHSQALVELTEQLEQARRGKSVWEKTRLSLEAEVSELKTELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARAEAAEKLQRAQVELESVSTALSEAESKAIRLSKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVV-ARERAGRELQTTQAQLSEWRRRQE-EEAAVLEAGEE-ARRRAAREAETLAQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERVEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARRVAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQAQMKELWREVEETRSSREEMFTLSRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLGQLEEELEEEQNNSELLKDHYRKLVLQVETLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEEEAEGAE------------PGSAPTQEPE------APPPAAPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z406-1", "uniprot_id": "MYH14_HUMAN", "id": "Q7Z406-1", "name": "Myosin-14", "aln": "---------------------------------------MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEG-EEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVP--------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLG-GAGEQLKADLLLEPCS-HYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRH---LRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-----------------------------------------VEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA-----CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH-WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGEL--EDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA-ARERAGRELQTAQAQLSEWRRRQE-EEAGALEAGEE-ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEE-AEEAQ------------PGSGPSPEPE------GSPPAHPQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B482-1", "uniprot_id": "A0A8M2B482_DANRE", "id": "A0A8M2B482-1", "name": "", "aln": "--------------------------------------MSRPAGGSINDVACFLSTGAGPGSPTSVFSAS--------------SQADWAAKRLVWVPSEKHGFESASIREER-GDEVEVELTDSGRKLTLLREELQRMNPPRFSKVEDMADLTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKNLPIYTESIIEMYRGKK------------RHEMPPHIYAISEAAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSGTLGRPKDTVVQMDGTRS--------------------LGRGSSAVNRTVQYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDERTFHIFYQLLS-GATEAMRKELLLGGAD-QYRFLCGGSL-PVPGQSDSENFTQTMDSMTIMGFTQEESTSMLKVISSVLQFGNITFHKEKNTDQASMPDDTAAQKLCHLLGISVLEFSRAILTPRIKVGREYVQKAQTKQQADFAVEALAKATYERLFRWLVHRINRALDRRQRQGASFIGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIEWNFIDFGLDLQPCIDLIERPAHPPGVLALLDEECWFPRATDRSFVDKLSAEQ-GSHSKFMRPRQ---LKEEADFSIIHYAGKVDYKANEWLVKNMDPLNDNVASLLHQSSDPFISELWREDIQTLPRVYFFDSYATLQTNG-----------------CDSMERIVGLDQVSSGENSGPVSFGAAGLKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFLRCIIPNHEKRAGKLSPHLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYEILTPNAIPRT-FMDGKHA-----SELMISALELDKNLFRVGQSKVFFRAGVLAHLEEERDLKITDTIIRFQSAARGYLARKAFHKKQQQLSALRVMQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQDEEIQAREAQLQKAKDKLSKLELDFTELDKKNQQLIEEKSVLTDQLQAEAELFAEAEEMRARLANRKQELEDVLGELESRLEEEEERTVQLTNEKKRIQQHVQDLEEQLEEEEGTRQRLQLEKVTLESKVKSLEAETLTLAEQRDRLSKEKKQLEERLNEVTDQLTEEEEKVKSLNKLKNKQEAVIADIEERLKREEQGRLEQEKWKRRMEGEAVEAQEQLSDMSLLVTELRGSLSQREKEITTLQTRLEEEGARRTEAQRALREAMSQVSELKEEVENERGMRERAEKQRRDLGEELEALRTEL--EDTLDTTAAQQELRSRREAELGELQRCLEEETRRHEAQLSELRIKHTAAIDSLQEQLDNAKRSRQSLEKAKAVLEEERLNLSAELKTLQGGKMESERGRKRAEGQLQELNARLSQAEREREEREERLGKLQSELESLSSSLSSSDSKSHRLHKEVSSLESQLHDVQELLQEETRQKLALGSRVRALEEEKAGLMERLEEEEE-KTRELTRQIQNHTQQLADLKRQTE-EVNSAVEAGEE-TRRKMQRDLENAVQREKSKEEEKERIERQKERLREEIEDMTIALQRERQNCTALEKRQKKFDQCLAEEKAVSARLQEERDRAEAESREKETRFLSLSRALQEATEQRDELERTNKQLRLEMEQLVNAQDDVGKNVHELERSRRALETEAQSLKEQTQELEDELGEAENARLRLEVTLQALRAQFEREISTKEEKGEEKRRALNKQVRELETMLEEEKTQRAQALTVKKQLETELQEAEAQVEAASRGREEAFRQMKRLQTQMKELIRELDETKLARDEIVAQSKDSEKRLQTLEAELLQLTEDLSVSERQKRQAQQERDEMADEIINNATGKSALFDEKRRLETRITQMEEELEEAQSNAELLAERQRKSTLQIETLTVQLSGERTLAQKSESARETLERQNKELKTRLSEMEGAVKGKHRLSVAALEAKIESMEEQVEQERQERAMANKLVRKTEKKLKEVLMQVEDERRHADQYREQLDKSMGRLRQLKRQLEEVEEENSRSNAQRRKLQRELEEMSDSMQSMNRELNTLRSQLSITERQKSEQRAPLPLSMRAGRRALVDDLSQENSDSEDPGASPT------------PSSGPPGTPTPSDNALGPPPPYSLTDAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99323-3", "uniprot_id": "MYSN_DROME", "id": "Q99323-3", "name": "Myosin heavy chain, non-muscle", "aln": "MKSAWLALKSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSVERNQFNDP-------------ATQAEWTQKRLVWVPHENQGFVAASIKREH-GDEVEVELAETGKRVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIK------------RHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLA-GATPEQREKFILDDVK-SYAFLSNGSL-PVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG---GIMALLDEECWFPKATDKTFVDKLVSAH-SMHPKFMKT-D---FRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKD------------------------------------------AEIVGMAQQALTD-------TQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKG-FMDGKKA-----CEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRN-WQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNEL--LDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDE-AKRNYERKLAEVTTQMQEIKKKAE-EDADLAKELEE-GKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR--------RTGGIGLSSSRLTGTPSSKRAGGGGGGDDSSVQDE-------------SLDGEDSAN------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "---------------------------------------------MTGGQSCSSNMIVWIPDEKEVFVKG-------------------------ELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPS-----------------------------------------NIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKN---DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLD-HGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRL------KNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPE----------------------------------------------GEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFN---DKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIP-LDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSS---DIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQ------------YTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEK--------------DAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLS--DTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYES------TMIGSKNIDSNNAQSKIFS---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ***:::::: *: :: . . . :.:.* : : :* ::: *. :*::***:* :*:*******:*:: *. * : ..*: *:***:* : * :*::* : : . : :. ::.: :: : . :: *.: : : :: : *: :.*.: * :.:. *. *:.: ::::* ::: * *: ::*:** :****:: * :******:*******:** :*:***.* :*.: * :.:* *: *::*: *::.:*:**. :*:::* * *: : . * : **** * * *: ** **:.: * :: : : .:*. *: * * . *: *: ** * . ::.** ******* *:. :.:* : : :* ** :: . . :. :: ::: :: * :*:**:: .* :* :* :: . : :. * : . : : * :: ::** . . . . . : . . :. . : : .: : : . . . : . .. : : : * : * * . : . . : . : : . . : . * : : ::* . .: : . : :: : : : :: : : : : .:.: : : . .: :: :: ::: :* : . :: . * :. * : : :: :::: : .:: . .: : . : :: :: .. : . : : ", "identical_positions": 138, "similar_positions": 300, "identity": "6.29%" }, { "cls_id": "homologset.agr.SGD:S000001066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC61-1", "uniprot_id": "MPPA_MOUSE", "id": "Q9DC61-1", "name": "Mitochondrial-processing peptidase subunit alpha", "aln": "MATAVWAAARLLRGSAVL-CARPRFGSPAHRRFSSGATYPNIPLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVDLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIAKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLVGAEPAWGAPGTVDVDRSVAQYTGGIIKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDL----VELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLR----------GKPAVAALGDLTDLPTYEHIQAALSSRNGHLPRSYRLFR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20069-1", "uniprot_id": "MPPA_RAT", "id": "P20069-1", "name": "Mitochondrial-processing peptidase subunit alpha", "aln": "MATAVWAAARLLRGSAAL-CARPKFGSPAHRRFSSGATYPNIPLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTLGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVGLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIGKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGVQPAWGAPGAVWMLTAQWHSTRGGSSRWRETCQMSALRPPRFQSSHIYGGARELLLLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDL----VELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLR----------GKPAVAALGDLTDLPTYEHIQAALSSRDGRLPRTYRLFR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10713-1", "uniprot_id": "MPPA_HUMAN", "id": "Q10713-1", "name": "Mitochondrial-processing peptidase subunit alpha", "aln": "MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVDT----VELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRVASKMLR----------GKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11914-1", "uniprot_id": "MPPA_YEAST", "id": "P11914-1", "name": "Mitochondrial-processing peptidase subunit alpha", "aln": "-----------------------MLRNGVQRLYSNIARTDNFKLSS-------------------------LANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGR-AMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWMKP--ELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPP-----ITKKVAQYTGG-----ESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * :*. . *: *** * ***:**:.*. *:*.::*: *::***:*.: *.* :*:*::***.** :.:.: : *** ** :* :**:. ** .*. .:.:..:: *:::.* *::*::*:: :::.::*:::: ::* * :*.*::* **: :*:* :** * : .*.: * .* .::***:. * * *** **: :: :.*** . :.: . : : * * .. : : ** * . : . *: .:*.*: ::***************:**** :***::::: *..:::***.*:*:: * *. *: . : **:*:::: . * *:.***.** * *:*****: * :**:***** : :*: : *.::**:*:.***. :: *:.:*. ** .: *:: * . :. .:. : ", "identical_positions": 153, "similar_positions": 173, "identity": "28.18%" }, { "cls_id": "homologset.agr.SGD:S000001068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XD13-1", "uniprot_id": "A0A8J8XD13_RAT", "id": "A0A8J8XD13-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LELLYLGIFVAFWACMIVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V37-1", "uniprot_id": "VATO_MOUSE", "id": "Q91V37-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LELLYLGIFVAFWACMVVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATEPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99437-1", "uniprot_id": "VATO_HUMAN", "id": "Q99437-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LALLYSGVFVAFWACALAVGVCYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFE3-1", "uniprot_id": "Q9VFE3_DROME", "id": "Q9VFE3-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "MAAQI------RTVVSQTFLWLFLAVATILTLYFV--MTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGAALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSMETALSQAAIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLFGLIVGIYMTSKSKMGDKE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE5-1", "uniprot_id": "Q9VFE5_DROME", "id": "Q9VFE5-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "MISKM------SFGLFFMLFVLGAASLGAVGIIFANVMVNMGERMGLGWFLYTSNPFLWSGMGIFLACALSVLGAASGIYMIGCSVAGGGVRSPRIKTKNLISVIFCEAVAIYGLITAILLSGNVNKFSSVRLITDSTVMATNMFTGFATFGAGLCVGMVNVACGIAVGIVGSGAALADAANSALFVKILIVEIFGSAIGLFGLIVAIYMTSKAETIN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23968-1", "uniprot_id": "VATO_YEAST", "id": "P23968-1", "name": "V-type proton ATPase subunit c''", "aln": "MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVAT-----AENMYSKSNLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . : : . * .... ** :.*::*: :** *. .***:*** **. * *: *.**::***.****:*:****.*****:* **::*. : * .:*: * **: ** *: **:.***.*: **::** :.:******::***** :**:*:**.: :.: . : ", "identical_positions": 77, "similar_positions": 59, "identity": "35.0%" }, { "cls_id": "homologset.agr.SGD:S000001069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZT9-1", "uniprot_id": "PSMD2_RAT", "id": "Q4FZT9-1", "name": "26S proteasome non-ATPase regulatory subunit 2", "aln": "MEEGGRDKTPVQSQQPSATAPSGADEKSSGKERRDAGEKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKCFAADIISVLAMTMS--GERECLKYRLVGSQEE-LASWGHEYVRHLAGEVAKEWQELDD---------------------AEKAQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYSKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRN-ECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGD-----SKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICS-----------------------------------------------------------------EHFDSKEKEEDKDKKEK---KDKDK----------KEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYNL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDM4-1", "uniprot_id": "PSMD2_MOUSE", "id": "Q8VDM4-1", "name": "26S proteasome non-ATPase regulatory subunit 2", "aln": "MEEGGRDKTPVQSQQPSATTPSGADEKSSGKERRDAGEKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKCFAADIISVLAMTMS--GERECLKYRLVGSQEE-LASWGHEYVRHLAGEVAKEWQELDD---------------------AEKAQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRN-ECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGD-----SKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICS-----------------------------------------------------------------EHFDSKEKEEDKDKKEK---KDKDK----------KEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13200-1", "uniprot_id": "PSMD2_HUMAN", "id": "Q13200-1", "name": "26S proteasome non-ATPase regulatory subunit 2", "aln": "MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKRFAADIISVLAMTMS--GERECLKYRLVGSQEE-LASWGHEYVRHLAGEVAKEWQELDD---------------------AEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRN-ECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGD-----SKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICS-----------------------------------------------------------------EHFDSKEKEEDKDKKEK---KDKDK----------KEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW54-1", "uniprot_id": "Q9VW54_DROME", "id": "Q9VW54-1", "name": "26S proteasome non-ATPase regulatory subunit 2", "aln": "--MTGETKLEKKPLKPAASEGDAKDPKAKKDEKKDGKDKEQQPELSDEDQQLQEELELLVQHLQEPDAKLYQPTLESMAKLIRASTTSMTSVPKPLKFMRPHYETMKTVYKHMPNEQARQLCADIISVLSMTMG--SGKDCLAYRFLCDRKQRIGDWGHEYVRHLSGEISAHYHDTTG---------------------DFRVQ---LIELVKQIIPYNMEHNAEADACDLLIEIDHLHLLSDFVDESAYPRVCLYLQSCYPYVPDPDNTIILETALQLSRKFNQYTQAMRLALMLNDMDKIGEIFKEPKEPAMQKQLAFMLARQQICLELDELVPDYDDLMEIMSNANLNKHFLNLARELDIMEPKTPEDIYKSHLDNSRSRFASIQVDSAKQNLAASFVNGFVNAGFGVDKLLSEDGNKWLYKNKEHGMLSATASLGLILLWDVDGGLTMIDKYLYSTDDNIKSGALLACGIVNCGIRN-EVDPAHALLSDYIDNQNSCMRVGAILGLGIAYAGSNRSIVIDTLKTVFSFGSNNKSSASVEILGITALSLGLISVGSCNSEITEILLQTIMGLTKADLKDTYTRFLFLGLGLLYLGRQKSTEAVMMTLEVLEEPYRSMATTMVDICAYAGTGNVLKIQQLLHICS-----------------------------------------------------------------DHYETSSADDEKEKSKKDKGKDKEKEKE---KEKEKEREKDLSATQSIAVLGIALIAMGEDIGAEMAYRSFGNLLRYCEPAIRRAVPLALGLISASNPKLNIIDTLSKFSHDSDAEVAHNAIFAMGLVGAGTNNARLASMLRQLAQYHSKDPSNLFMVRIAQSLTHLGKGTLSLSPYHSDRQLMNPMAVAGLMATLVSLLDVKNLILNRSHYLLYTLVPAMQARMLITFDEELNQLQVPVRVGIAIDVVGQAGKPKTITGFQTHTTPVLLAIGERAELATDEYLALTPVMEGFVILKKNPNFVK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38764-1", "uniprot_id": "RPN1_YEAST", "id": "P38764-1", "name": "26S proteasome regulatory subunit RPN1", "aln": "--MVDESDKKQQTIDEQSQISPEKQTPNKKDKK-----KEEEEQLSEEDAKLKTDLELLVERLKEDDSSLYEASLNALKESIKNSTSSMTAVPKPLKFLRPTYPDLCSIYDKWTDPNLKSSLADVLSILAMTYSENGKHDSLRYRLLSDVSD-FEGWGHEYIRHLALEIGEVYNDQVEKDAEDETSSDGSKSDGSAATSGFEFSKEDTLRLCLDIVPYFLKHNGEEDAVDLLLEIESIDKLPQFVDENTFQRVCQYMVACVPLLPPPEDVAFLKTAYSIYLSQNELTDAIALAVRLGEEDMIRSVFDATSDPVMHKQLAYILAAQ-------KTSFEYEGVQDIIGNGKLSEHFLYLAKELNLTGPKVPEDIYKSHLDNSKSVFSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDNDN-WVYKTKGDGMTSAVASIGSIYQWNLDG-LQQLDKYLYVDEPEVKAGALLGIGISASGVHDGEVEPALLLLQDYVTNPDTKISSAAILGLGIAFAGSKNDEVLGLLLPIAAS-----TDLPIETAAMASLALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLALALGILYMGQGEQVDDVLETISAIEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLHRLTPKNVKGEEDADEEETAEGQTNSISDFLGEQVNEPTKNEEAEIEVDEMEVDAEGEEVEVKAEITEKKNGESLEGEEIKSEEKKGKSSDKDATTDGKNDDEEEEKEAGIVDELAYAVLGIALIALGEDIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGIVSVSDPQMKVFDTLTRFSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITRLAQGLLHLGKGTMTMDVFN-DAHVLNKVTLASILTTAVGLVSPS--FMLKHHQLFYMLNAGIRPKFILALNDEGEPIKVNVRVGQAVETVGQAGRPKKITGWITQSTPVLLNHGERAELETDEYISYTSHIEGVVILKKNPDYREEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . :. . : : . .:: *::: :**:** :*: :**:**::* * *:.**..:*: : . *: **:***:*******:** * : :*.: . : : **::*:*:** . . ::.* **:: . .: : .*****:***: *:. ::: . . : * :*:** : **.* :* ***:**: :. * . :**.:: :** *: :* :* *:: :*. * : . .. .:*: **: *.: : : .:* .: .::**:*::*. : : :*:.: :*:.* :*..:** **:**:: **.*:****:**:*.: :. :***: ***:******:* .: ***: ::.* *:**.* .** **.**:* * *::** * :***** : :*:****. ** .*::: * :** **.**: : .. : .:*:***:*:***:.. *: * .: . :. .:* .:::*: . : **:**.::* :::.:: : :** :.*:* *.**: ::*: : : :: ::..:..* * .:*. ***:*:*:** :*:*** : .: :: . :: *.:.:* .**: :* .: . *********:**:** **: * **:*::* : :** ****:.::*.*:*:::::***::****:* **: *:*****: *:******** :*****.*:::: . **:.*:**.* ******::: :: * :::. :::*.:::. *.::. :: : * ::* * ..::.::::::::* . : * **** *::.*****:**.***: *::***** ****** *:*::. *. :**.***:***:: ", "identical_positions": 319, "similar_positions": 346, "identity": "31.34%" }, { "cls_id": "homologset.agr.SGD:S000001070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28843-1", "uniprot_id": "DPP4_MOUSE", "id": "P28843-1", "name": "Dipeptidyl peptidase 4", "aln": "----------------MKTPWKVLLGLLGVAALVTIITVPIVLLSK---------------DEAAADSRRTYSLADYLKSTFRVKSYSLWWVSDFEYLYK---------QENNILLLNAEHGNSSIFLENSTFESFG------YHSVSPDRLFVLLEYNYVKQWRHSYTASYNIYDVNKRQLITEEKIPNNTQWITWSPEGHKLAYVWKNDIYVKVEPHLPSHRITSTGEENVIYNGITDWVYEEEVFGAYSALWWSPNNTFLAYAQFNDTGVPLIEYSFYSD---ESLQYPKTVWIPYPKAGAVNPTVKFFIVNIDSLSSSSSAAPIQIPAPASVARGDHYLCDVVWATEERISLQWLRRIQNYSVMAICDYDKINLTWNCPSEQQHVEMSTTGWVGRFRPAEPHFTSDGSSFYKIISDKDGYKHICHFPKDKKD---CTFITKGAWEVIS-IEALTS--DYLYYISNQYKEMPGGRNLYKIQLTDHTNVKCLSCDLNPERCQYYAVSFSKEAKYYQLGCWGPGLPLYTLHRSTD------------HKELRVLEDNSALDRMLQDVQMPSKKLDFIVLNETRF------WYQMILPPHFDK--SKKYPLLLDVYAGPCSQKADASFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTLEVEDQIEAARQFVK-MGFVDSKRVAIWGWSYGGYVTSMVLGSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPIPEDNLDHYRNSTVMSRAEHFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVD-FQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14740-1", "uniprot_id": "DPP4_RAT", "id": "P14740-1", "name": "Dipeptidyl peptidase 4", "aln": "----------------MKTPWKVLLGLLGVAALVTIITVPVVLLNK---------------DEAAADSRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYK---------QENNILLFNAEHGNSSIFLENSTFEIFGDSI--SDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSD---ESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVIS-IEALTS--DYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTD------------QKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRF------WYQMILPPHFDK--SKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLK-MGFVDSKRVAIWGWSYGGYVTSMVLGSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVD-FQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27487-1", "uniprot_id": "DPP4_HUMAN", "id": "P27487-1", "name": "Dipeptidyl peptidase 4", "aln": "----------------MKTPWKVLLGLLGAAALVTIITVPVVLLNKGT-------------DDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYK---------QENNILVFNAEYGNSSVFLENSTFDEFGHSI--NDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSD---ESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD---CTFITKGTWEVIG-IEALTS--DYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVN------------DKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKF------WYQMILPPHFDK--SKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK-MGFVDNKRIAIWGWSYGGYVTSMVLGSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVD-FQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMM2-1", "uniprot_id": "Q9VMM2_DROME", "id": "Q9VMM2-1", "name": "Venom dipeptidyl peptidase 4", "aln": "----------------MPINPLLITAFGLFITVCPRPSTAAAVIGR---------------VDGAEGNKTAWELTEALYGTSGLRSFNGTWITG-TYYTA---------TDRSIHKFNAATKTDVIFQNSSFLNNYVG----ATFSLSPDNTKILIRHNLTEKFRHSYIAQYDVFDIETNTTVQIHKGEK-LQYCGWSPLRDRLAYVYLNNVFIHFSESLEIS-ITDDGVDGVVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVS----DNDPTMHTIVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQNLTSIQSCSYEG-----DCVEVKRLEEP--QGWVDISTP--KCLSTGKSCIFGYFIDN--WHQVWNLDLETGLN---SWQSRGNFTVLS-VYGYDEARDKLYYQA----TLPGDPSVYHVFSNDE-CLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEAST------------KTLQVDWEPNTAYRKQIEEKLRPSYRFMNVTLADGSIG-----YAKLALPPNFVE--TKKYPLIVVVYQGPNSVRVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQ-FEEQTYTDENHGIGN--ALPHLYHTIDAFWTNCLNLDVYEDSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18962-1", "uniprot_id": "DAP2_YEAST", "id": "P18962-1", "name": "Dipeptidyl aminopeptidase B", "aln": "MEGGEEEVERIPDELFDTKKKHLLDKLIRVGIILVLLIWGTVLLLKSIPHHSNTPDYQEPNSNYTNDGKLKVSFSVVRNNTFQPKYHELQWISDNKIESNDLGLYVTFMNDSYVVKSVYDDSYNSVLLEGKTFIHNGQNLTVESITASPDLKRLLIRTNSVQNWRHSTFGSYFVYDKSSS---SFEEIGNEVALAIWSPNSNDIAYVQDNNIYIYSAISKKTIRAVTNDGSSFLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIPYYVQ--DEKDIYPEMRSIKYPKSGTPNPHAELWVYSMK------DGTSFHPRISGNKKDGSLLITEVTWVGNGNVLVKTTDRSSDILTVFLIDTIAKTSN-VVRNESSNGGWWEITHNTLFIPANETFDRPHNGYVDILPIG-GYNHLAYFENSNSSH--YKTLTEGKWEVVNGPLAFDSMENRLYFIS-----TRKSSTERHVYYIDLRSPNEIIEVTDTSEDGVYDVSFSSGRRFGLLTYKGPKVPYQKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKDEFGKDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISAASLYGS-LTFVDPQKISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQ--ENFDGYVESSVHNVTALAQANRFLLMHGTGDDNVHFQNSLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANVIVFDKLLDWAKRAFDGQFVK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : .:: : : : ..: :: .* : .. *::. : : . :: :.. : : *** :*:. * .:::*** ..* ::* .. .. : ** . :*** *:::: . . ...::** *******:: .* ***. . ** :::: * : * : **. : ***:*: ** ..: : . . . . .. : .*.* . .: : * .: : . * : . . :.:: : . . :.* : *:. . . : **: : . . :: * . : ::*. : * ** . : . * * . : ::: * : : * . : ** .* : :.:**::. .* ** * :. * :.: ::: : * . .****:* :*..: :. ** *..**: .: . : *** :: .::*******:* .: .... *: *::****: * :**::****** * :*:. * :*:* . : :**:**:.*****:*:* : . * .:: :: :.*.:*.* * :: : : ..:. ", "identical_positions": 129, "similar_positions": 225, "identity": "15.28%" }, { "cls_id": "homologset.agr.SGD:S000001071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXN7-1", "uniprot_id": "PBLD2_MOUSE", "id": "Q9CXN7-1", "name": "Phenazine biosynthesis-like domain-containing protein 2", "aln": "--MKLPIFIADAFTATAFRGNPAAVC----LLERTLDEDAHQDIAREMNLSETAFVRKLQPTDDFTQSSRFGLRWFTPEAEFPLCGHATLASAAVLFQKRKNTNSTLTFVTMSGELKARREEDGIVLDFPVYPTFPQDFHEVEDLIKAAIGDTLVQDIRYSPDTKNLLVRLSDSYDRSFLESLKVNTEPLPAIEKTGKVRGLILTVKGEPGGQTALYDFYSRCFAPWVGVAEDPVTGSTHTLLGPYWSEELGKKEMRAFQCS-----RRGGELDINLRPDGR----VDIKGGAVIVLEGTLTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DCG6-1", "uniprot_id": "PBLD1_MOUSE", "id": "Q9DCG6-1", "name": "Phenazine biosynthesis-like domain-containing protein 1", "aln": "--MKLPIFIADAFTATAFRGNPAAVC----LLERTLEEDAHQQIAREMNLSETAFIRKLQPTDSFTQSSRFGLRWFTPVSEVPLCGHATLASAAVLFHKIQNRNSTLTFVTMSGELKARRAEDGIVLDFPVYPTFPQDFHEVEDLIKAAIGDTLVQDIRYSTDTRKLLVRLSDSYDRSFLESLKVNTEPLPAIEKTGKVRGLILTVKGEPGGQTAPYDFYSRYFAPWVGIAEDPVTGSAHTVLSSYWSQQLRKKEMRAFQCS-----RRGGELDISLRPDGR----VDIKGGAVIVLEGTLTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G1G3-1", "uniprot_id": "A0A8I6G1G3_RAT", "id": "A0A8I6G1G3-1", "name": "", "aln": "--MKLPIFIADAFTVTAFHGNPAAVC----LLESTLDEDAHQHIAREMNLSETAFVRKLQPTDNFTQSSRFGLRWFTPEAEFPLCGHATLASAAVLFHKRKNVNSTLTFVTMSGELKARRAEDGIVLDFPLYPTFPQ---IIEDLIKAAIGDTVVQDIRDS--FFFFFKYFIYYIFESFLESLKVNTEPLPGIEKTGKVKGLILTVKGESGGQTTPY------FAPWFGVPEDPVTGSTHTLLGPYWSEELGKKEMRAFQCS-----CRGGELDISLRPDGR----VDMKGGAAVVLEGMLTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68G31-1", "uniprot_id": "PBLD_RAT", "id": "Q68G31-1", "name": "Phenazine biosynthesis-like domain-containing protein", "aln": "--MKLPIFIADAFTVTAFHGNPAAVC----LLESILQEDAHQQIAREMNLSETAFIRKLQPTDSFSQSSCFGLRWFTPVSEVPLCGHATMASAAVLFHKIKNVNSTLTFVTLSGELKARRAEDGIVLDFPLYPTFPQDFHEVKDLIKAAIGDTTVQDIQYSPDTRKLLVRLSDSYDRSFLESLKVNTEPLPGIEKTGKVKGLILTVKGESGGQTTPYDFYSRYFAPWVGVPEDPVTGSAHTVLSSYWSQQLGKKEMRAFQCS-----CRGGELDISLRPDGR----VDMKGGAAVVLEGMLTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30039-1", "uniprot_id": "PBLD_HUMAN", "id": "P30039-1", "name": "Phenazine biosynthesis-like domain-containing protein", "aln": "--MKLPIFIADAFTARAFRGNPAAVC----LLENELDEDMHQKIAREMNLSETAFIRKLHPTDNFAQSSCFGLRWFTPASEVPLCGHATLASAAVLFHKIKNMNSTLTFVTLSGELRARRAEDGIVLDLPLYPAHPQDFHEVEDLIKTAIGNTLVQDICYSPDTQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWVGVAEDPVTGSAHAVLSSYWSQHLGKKEMHAFQCS-----HRGGELGISLRPDGR----VDIRGGAAVVLEGTLTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38765-1", "uniprot_id": "YHI9_YEAST", "id": "P38765-1", "name": "Uncharacterized isomerase YHI9", "aln": "MTLMVPFKQVDVFTEKPFMGNPVAVINFLEIDENEVSQEELQAIANWTNLSETTFL--FKPSD---KKYDYKLRIFTPRSELPFAGHPTIGSCKAFLEFTKNTTATSLVQECKIGAVPITINEGLISFKAPMADYESISSEMIADYEKAIGLKFIKPPALLHTGPEWIVALVEDAETCFNANP--NFAMLAHQTKQNDHVGIILAGPKKEAAIKNSYEMR--AFAPVINVYEDPVCGSGSVALARYLQEVYKFEKTTDITISEGGRLKRNGLMLASIKKEADNSTSYYIAGHATTVIDGKIKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: .*.** .* ***.** : * :.:: * **. *****:*: ::*:* :. : ** *** :*.*:.**.*:.*. .::. :* .:* . . . ::*:: . . . . : : *** . :: : : .* . * * : .. *:**: : .. . : *** ..: **** ** . *. * .: :: : * *.* : .:: :. : * *. *::* :..", "identical_positions": 63, "similar_positions": 90, "identity": "20.79%" }, { "cls_id": "homologset.agr.SGD:S000001072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS8-1", "uniprot_id": "MK07_MOUSE", "id": "Q9WVS8-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSGEPPGRVKAEPVHTAASVVAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSAR--RRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILKPT--------VPYGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLP-PRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAE--IEDFHARREGIRQQIRFQPSLQPVASEPVCPDVEMPSPWAPSGDCAMESPPPALPPCSDPAPDTVDLTLQPAPPASELAPPKREGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGTLGGPSTDPLAGLVLSDNDRSLLERWTRMARPPAP----APAPAPAPAPAPSSAQPTSTPTGPVSQSTGP-LQPAGSIPGPASQPVCPPPGPVPQPAG-----PIPAPLQTAPSTSLLASQSLVPPSGLPGSGAPEVLPYFPSGPPPPDPGLTPQPSTSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLSDLPDLQEP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C865-1", "uniprot_id": "MK07_RAT", "id": "P0C865-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSGEPPGRVKAEPVHTAASVVAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSAR--RRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILRPT--------VPYGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLP-PRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAE--IEDFHARREGIRQQIRFQPSLQPVASEPVCPDVEMPSPWAPSGDCAMESPPPALPPCSGPAPDTVDLTLQPAPPASELAPPKREGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGTLGGPSTDPLAGLVLSDNDRSLLERWTRMARPPVP----APAPAPAPTPKPSSAQPTSPPNGPVSQSTAP-LQPAGSIPGPASQPVCPPPGPVPQPAG-----PVPAPLQTAPSTSLLASQSLVPPSGLPGSGAPEVLPYFPSGPPPPDPGLTPQPSTSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLSDLPDLQEP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13164-1", "uniprot_id": "MK07_HUMAN", "id": "Q13164-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSAR--RRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILRPT--------VPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLP-PRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAE--IEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00772-1", "uniprot_id": "SLT2_YEAST", "id": "Q00772-1", "name": "Mitogen-activated protein kinase SLT2/MPK1", "aln": "--------------------------------MADKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVF--------YPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLG-FIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVN-DMEDLKQMVIQE--VQDFRLF----------------------------------------------------------------------------------------------------------------VRQPLLEEQRQLQLQQQQQQQQQQQQQQQ--------------------------------------------------------------------QPSDVDNGNAAASEEN------------------------------------YPKQMATSNSVAPQQ--------------ESFGIHSQNLPRHDADFPPRPQES------MMEMRPATGNTADIPPQNDNGTLLDLEKELEFGLDRKYF-------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A4D6K823-1", "uniprot_id": "A0A4D6K823_DROME", "id": "A0A4D6K823-1", "name": "Mitogen-activated protein kinase", "aln": "---------------MSVSMSLVQGGAAGGAPQGASAILAAAAPYYQPPAVPQDVQPDRPIGYGAFGVVWAVT--DPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK-HENVLSALDILQPP--------HLD-FFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVN-SNCVLKICDFGLAR---VEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTS-AGMRQYTADFEPSAGQP--FDDLWER-------------------------------------------------------------------------------------------------------------------KLTSVQQVKEEMHKFIAEQLQTG--------------------------------------------------------------------------------------------------------------------------RVPLCINPQS--------------------AAFKSFASSTVAHPSELPPSPHQWEX--------RQNEAIAA----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0V360-1", "uniprot_id": "B0V360_DANRE", "id": "B0V360-1", "name": "Mitogen-activated protein kinase 4", "aln": "-----------------------------------MAWHNTSPFR-YGFDLGAQYQDLRPLGTGASGLVLSAL--DRRSGLRVAVKKL--VMRDAVSVKHALREVKITRRLQ-HENVVRVYDVLGSSGHPLPRD---LTHVAAIYIVQECMETDLARLLEQG-PLPAEHATLLFYQLLRGLKFIHSANVLHRDLKPANIFINTEQMLLKIGDFGLAR-IVDPHYSHKGYLSEGMVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILDTVPVIREEDRQELLR--VMPSLVGHGWQIRRS-FRDLMPEVEDKAIDFLESILTFNPMDRLTAEAALCQPFLQRYSCPQDEPVSLQPFRIEDELEDSLVTESTHTHGLRSHWDRYDSSLSSDVYWPTQDQCGCMQSVSELGEAEDEEVQRDPRASS-ASHIEEAQVDPRKYSHSSSAERFLEQSHPSL---------ERICGHFSELDCGRSCDYKVGSPSYLDKIAWREGKPQHYSEPKLILDLSNWRNNSMAAPRQNSAEKLLTEP--------------------------------------------GDLFQEISRWVESTQSGLHSPGSPQEPPSSPCS-------PPLPLSPTLMPQS-QIQIPAPL-TLPSPLSRRSPTPFFSAPPS---------------LLPSSPSSPHHGSSNYPSSSIG--CENYEEPSQMRP--------------SGEEHFDLDVFISQALQICSQSEIMESS------DDLKSDNISDVCNVSDDHRPSRTQTPTPEMVKAHG--CHKEHW-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA57WKX4-1", "uniprot_id": "A0AA57WKX4_DANRE", "id": "A0AA57WKX4-1", "name": "Mitogen-activated protein kinase 6", "aln": "-----------------------------------MAEKFESLMNIHGFDLGPRYMDLKPLGYGGNGLVFSAV--DTDCDKRVAVKKI--VLTDPQSVKHALREIKIIRRLD-HDNIVKVFETLGPSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQG-LLSEDHARLFMYQLLRGLKYIHSANVLHRDLKPANLFVNTEDLVLKIGDFGLAR-IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRLELQS--VIPVFIKNDMSEPHTPLAKLLPGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHIEDEVDDILLMDESHSQVYN--WDRYHESQFSDQDWH-------LHSTHEL-----EDVQRDPRALSDVTDEEEVQIDPRKYMDG-DCEKFLEDPSFDLPPEHLWQLEDHHENKYCDQECSYTCNYKAVSPSYLDNLIWRDSEVNHYYEPKLIIDLSNWKEQQSKEKIDKKGKSKCEKN--------------------------------------------GLVKAQIALKEASQNHTVPEKDRDQEKHQNHNQGFDFDSFIASTIKLSLQPESGDVDLLNELNTSVSQLDTRAPCGSMSKSISQEKEEKCLVNLAQLGVRAPCPWESFTDCGVAESSLIDQACWDVRKDEQLQKENSSCQSSYLDRLFSKRDDVEPEILEPVEVVSTTESDFISCSGEIVFNMQLESLAIPGFEGAADIPLKSIQATLAPSAVKHSPQIAHKTYSSIFKHLN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* *. *:* :. . **:**: .: *: :**:*: : *.*: : . :*: : :: *: ::: . *. * : **:* ***::*** ::***:**.*:::* : *** ***:** .: .::: :.*::**:*.:::. . *:.*:*:*:.***:.*:* : :* . . :.*:: * : . : : . . :*: :* :* *:* *::. ** :*:: .. . * : : : .. . . . : ", "identical_positions": 68, "similar_positions": 108, "identity": "8.17%" }, { "cls_id": "homologset.agr.SGD:S000001073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1HG60-1", "uniprot_id": "PIF1_RAT", "id": "Q1HG60-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "-------------MPSSTEVATDECDDTELRCRVAVEELSPGGQPRKRQALRAAELSLGRNERRELMLRLQAPGPEGRPRCFPLRAVRLFTRFAAVGRSTLRLPADGVPRAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ELRRAAATKAPDSALEKRPMESQP----SMEAPR---WPLPVKKLR-------MPSSKPKLSEEQAAVLRMVLKGQS-IFFTGSAGTGKSYLLKHILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVALAH-RPGVRQGWLNCQRLVIDEISMVEADFFDKLEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKG--------SQHPRFCFQAKSWRKCVPVTLELTEVWRQADQTFISLLKAVRLGRCSDEVTRQLRATAAHKVGRDGIIATRLCTHQDDVALTNEKRLKELPGDVHSFEAIDSDPE-LSRTLDAQCPVGRVLQLKLGAQVMLVKN------------------------------------LAVSRGLVNGARG------------------------------VVVGFESEGRGLPRVRFLCG----ITEVIRTDRWTVQVTG-GQYLSRQQLPLQLAWAMSIHKSQGMSLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPTVVRCDSRVLQFYATLRQGRG------LSLESQD----DEEASSDLENMDPNL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80SX8-1", "uniprot_id": "PIF1_MOUSE", "id": "Q80SX8-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "MRSGLCTPAEALEMPSSTEAATDECDDAELRCRVAVEELSPGGQPRKRQALRAAELSLGRNERRELMLRLQAPGPTGRPRCFPLRAVRLFTRFAATGRSTLRLPTDGVPGAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ELQRAAATKAPDSALEKRPMESQT----STEAPR---WPLPVKKLR-------MPSTKPKLSEEQAAVLRMVLKGQS-IFFTGSAGTGKSYLLKHILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCMALAN-RPGVRQGWLNCQRLVIDEISMVEADFFDKLEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKG--------SQQPQFCFQAKSWRRCVPVILELTEVWRQADQTFISLLQAVRLGRCSDEVTRQLRATAAHKVGRDGIVATRLCTHQDDVALTNEKWLKALPGDVHSFEAIDSDPE-LSRTLDAQCPVSRVLQLKLGAQVMLVKN------------------------------------LAVSRGLVNGARG------------------------------VVVGFESEGRGLPRVRFLCG----ITEVIRTDRWTVQVTG-GQYLSRQQLPLQLAWAISIHKSQGMSLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPTVVRCDSRVLHFYATLRQGRG------LSLESQD----DEEANSDLENMDPNL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H611-1", "uniprot_id": "PIF1_HUMAN", "id": "Q9H611-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "-------------MLSGIEAAAGEYEDSELRCRVAVEELSPGGQPRRRQALRTAELSLGRNERRELMLRLQAPGPAGRPRCFPLRAARLFTRFAEAGRSTLRLPAHDTPGAGAVQLLLSDCPPDRLRRFLRTLRLKLAAAPG-PGPASA------RAQLLGPRPRDFVTISPVQPE------ERRLRAATRVPDTTLVKRPVEPQAGAEPSTEAPR---WPLPVKRLS-------LPSTKPQLSEEQAAVLRAVLKGQS-IFFTGSAGTGKSYLLKRILGSLP----PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVALAQ-RPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQNKPFGGIQLIICGDFLQLPPVTKG--------SQPPRFCFQSKSWKRCVPVTLELTKVWRQADQTFISLLQAVRLGRCSDEVTRQLQATASHKVGRDGIVATRLCTHQDDVALTNERRLQELPGKVHRFEAMDSNPE-LASTLDAQCPVSQLLQLKLGAQVMLVKN------------------------------------LSVSRGLVNGARG------------------------------VVVGFEAEGRGLPQVRFLCG----VTEVIHADRWTVQATG-GQLLSRQQLPLQLAWAMSIHKSQGMTLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPMAVRCDPRVLHFYATLRRGRS------LSLESPD----DDEAASDQENMDPIL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV90-1", "uniprot_id": "PIF1_DANRE", "id": "Q7ZV90-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "--------------------MLGQMEPAELQCTVAVERLNPAGQAIKRQLIRKGTVTLGRNEFQEMILRVHDG---KAPQNFMLRDFQLFTRFAKDGKCTVKFVPENT------QVLVSDCPPDRLKMFLKTLSIKHQASQS-SKPLSD------REKLRAGLPRAFETVSPLQLKDVEKANELRSRVNAPMQPRCLAERPVNKVLGDRKQVKRPRPDCDASPVKALHPNKKPVLVLPVAQKLSKEQTAVLNAVLSGKN-VFFTGSAGTGKSFLLKRIVGSLP----PKSTYATASTGVAACHIGGTTLHSFAGIGSGSAPLEQCIELAQ-RPGVLRHWTSCKHLIIDEISMVEAEFFDKLEAIARSIRRSTEPFGGIQLIVCGDFLQLPPVTKG--------KEKANFCFQSRSWRKCIHMNMELMEVRRQTDKTFISLLQAVRVGRVTEEVTAQLLKSANHCIERDGILATRLCTHKDDVELTNENKLKQLPGVVRMYEAVDSDPM-LVQTIDAQSPVSRLLQLKVGAQVMLTKN------------------------------------LDVQRGLVNGARG------------------------------VVVDFQPGNQGLPRVRFLCG----AVEVMKRERWMFKAPG-GLYLSRQQLPLKLAWAISIHKSQGMTLDCVEISLARVFESGQAYVALSRARSLEGLRVMDFDPRVVQANQDVLIFYKRLRKERL------LMQSSMN----DFVGQSNKENSRW-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQR3-1", "uniprot_id": "Q9VQR3_DROME", "id": "Q9VQR3-1", "name": "ATP-dependent DNA helicase PIF1", "aln": "----------------------MDLNDAVLTCAVNMEWTNAVGITGRKLAYKTATLRLVRNDLRELFVEVTPEK--LKPLKFKLKDLMVHKKFMSEGKATFNFKAEKC------TLYLSNAPPGTLMFFLRTIFVKMNGNEGGSQPDDATLQKKLREHLMSGKPSSFNDVSPVTTA---EMILARKKAGLLSKGSVTTPSPQGAKKRRFEELKEEKERGTMPAAKKLYAS-----TTDESLRLSEEQMEVLRACTSGKS-VFFTGSAGTGKSFLLRRIISALP----PDGTVATASTGVAACLIGGTTLHAFAGIGGGDATMQRCLELAS-RPANAQTWRKCKRLIIDEISMVDGQFFEKIEAVARHIRRNDRPFGGIQLILCGDFLQLPPVIKGDFGAAPTATPQQRFCFQSSAWETCIQCVYELKQVHRQSDPEFVKILNHLRIGHVNDSITSRLAATSKQKIEGNGILATQLCSHTNDANSINESKLENLDGDKILFKADDSDAS-MTRTLDQQIQAPSQLYLKVNAQVMLLKN------------------------------------INISNGLVNGARG------------------------------VVVRMEKD---LPVVRFKNN----QEYVCKHERWIIKTAS-GNHITRRQVPLKLAWAFSIHKSQGLTLDCVEMSLSKVFEAGQAYVALSRAKSLQSIRILDFDAKQVWANPHVLQFYKGFRRKLMDTTMIPLGPKNKDKKPGDKAANSALAKLKKSLINKPLVSIS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38766-1", "uniprot_id": "RRM3_YEAST", "id": "P38766-1", "name": "ATP-dependent DNA helicase RRM3", "aln": "--------MFRSHASGNKKQWSKRSSNGSTPAASASGSHAYRQQTLSSFFMGCGKKSAAASKNSTTIIDLESGDEGNRNITAPPRPRLIRNNSSSLFSQSQGSFGDDDPD-AEFKKLVDVPRLNSYKKSSRSLSMTSSLHKTASASTTQKTYHFDEDETLREVTSVKSNSRQLSFTSTINIEDSSMKLSTDSERPAKRSKPSMEFQGLKLTVPKKIKPLLRKTVSNMDSMN--HRSASSPVVLTMEQERVVNLIVKKRTNVFYTGSAGTGKSVILQTIIRQLSSLYGKESIAITASTGLAAVTIGGSTLHKWSGIGIGNKTIDQLVKKIQSQKDLLAAWRYTKVLIIDEISMVDGNLLDKLEQIARRIRKNDDPFGGIQLVLTGDFFQLPPVAKKD------EHNVVKFCFESEMWKRCIQKTILLTKVFRQQDNKLIDILNAIRYGELTVDIAKTIRNLNRDIDYADGIAPTELYATRREVELSNVKKLQSLPGDLYEFKAVDNAPERYQAILDSSLMVEKVVALKEDAQVMMLKNKPDVELVNGSLGKVLFFVTESLVVKMKEIYKIVDDEVVMDMRLVSRVIGNPLLKESKEFRQDLNARPLARLERLKILINYAVKISPHKEKFPYVRWTVGKNKYIHELMVPERFPIDIPRENVGLERTQIPLMLCWALSIHKAQGQTIQRLKVDLRRIFEAGQVYVALSRAVTMDTLQVLNFDPGKIRTNERVKDFYKRLETLK------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .. :: : : : .. : . :. ::: :. . . . . . : * ... : *: ** *:. . :. :*:********* :*: *: *. . *****:** ***:*** ::*** *. .: : : : * : *:*******:.::::*:* :** :*:. *******:: ***:***** * .***:: *. *: * :* ** * ::.:*: :* *. . .:: : . :** .*.* : :. * *: * * ::* *. . :* . . : ** .****: ** : :. **. . * .* :. :* **: . : :*: .. . . : * *:** *.**:****:** ::: :::.* ::* :**.******* ::: :::::**. : : * ** :. ", "identical_positions": 134, "similar_positions": 154, "identity": "17.14%" }, { "cls_id": "homologset.agr.SGD:S000001074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN35-1", "uniprot_id": "A0ABK0LN35_RAT", "id": "A0ABK0LN35-1", "name": "Multidrug and toxin extrusion protein", "aln": "-----------------------------------------------------------------------------------------------------------MEPAEDSLGAAIQPPELAP--------------VPE-RSLRILLGLREALSSDVRQEAAALAALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFP-CWAIFLNTERLLLFLRQDPEVARLAQVYVMICIPALPAAFLFQLQTRYLQSQG------------------------------------IIMPQVIVGIAANVVNVGMNAFLLY--ALDLGVVGSAWANTTSQFFLSALLFLYVWWKGIHIHTWGGWT-----RECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCTGVCALLVGILLAALKDVVAYVFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNAIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVFFQALSYLIYILRTNWNRVAEQAQVRAGLKSN-------KEMIPTPADLPILEREVIDGVILPDIIRP-ESQTGQLVVEENSQCVVPTVGEVLTGRQLVVYRGTALIVSIAVLIAGIVVRVINDRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V050-1", "uniprot_id": "S47A2_MOUSE", "id": "Q3V050-1", "name": "Multidrug and toxin extrusion protein 2", "aln": "-----------------------------------------------------------------------------------------------------------MEPAEDSLGATIQPPELVR--------------VPRGRSLRILLGLRGALSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFP-CWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQG------------------------------------IIMPQVIVGIAANVVNVGMNAFLLY--ALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWT-----RECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQVRAGLKST-------KELIPTPADLPILEREVMDGVILPDIIRP-ESQTGQLVVEENSQCAVPTVGEVLTGRQLVFYRGMALTVSVAVLIAGIVVRVFNDRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K0H1-1", "uniprot_id": "S47A1_MOUSE", "id": "Q8K0H1-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------MERTEESAPGPGGA-----------------------DAASERRGLRCLLLPGFLEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFP-CWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQG------------------------------------IVLPQIMTGIAANLVNALANYVFLY--HLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWS-----WECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRGTGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLNWKRACQQAQVHANLKVN----VALNSAVSHEPAHPVCP-ESHGEIMMTDLEKKDETQLDQPMNQQQALPIRPKDSNKLSGKQLALRRGLLLLGVVLVLVGGILVRVYIRIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0E9-1", "uniprot_id": "S47A1_RAT", "id": "Q5I0E9-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------MEVLEEPAPGPGGA-----------------------DAA-ERRGLRRLLLSGFQEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFP-CWALFINTEQILLLFRQDPDVSRLTQTYVMVFIPALPAAFLYTLQVKYLLNQG------------------------------------IVLPQVITGIAANLVNALANYLFLH--QLHLGVMGSALANTISQFALAIFLFLYILWRKLHHATWGGWS-----WECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRGTGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSGIIICSVCQTSCFLVFIARLNWKLACQQAQVHANLKVN----VALNSAVSQEPAHPVGP-ESHGEIMMTDLEKKDEIQLDQQMNQQQALPVHPKDSNKLSGKQLALRRGLLFLGVVLVLVGGILVRVYIRTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96FL8-1", "uniprot_id": "S47A1_HUMAN", "id": "Q96FL8-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------MEAPEEPAPVRGGP-----------------------EATLEVRGSRCLRLSAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFP-CWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQG------------------------------------IVLPQIVTGVAANLVNALANYLFLH--QLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWS-----LECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNN-VPRSGNSALPQDPLHPGCP-ENLEGILTNDVGKTGEPQSDQQMRQEEPLPEHPQDGAKLSRKQLVLRRGLLLLGVFLILLVGILVRFYVRIQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86VL8-1", "uniprot_id": "S47A2_HUMAN", "id": "Q86VL8-1", "name": "Multidrug and toxin extrusion protein 2", "aln": "-----------------------------------------------------------------------------------------------------------MDSLQDTVALDHGG---------------------------CCPALSRLVPRGFGTEMWTLFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLP-CWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQGWLKGQEEESPFQTPGLSILHPSHSHLSRASFHLFQKITWPQVLSGVVGNCVNGVANYALVS--VLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWS-----SQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVFLATAAFVAYTARLDWKLAAEEAKKHSGRQQQQRAESTATRPGPEKAVLSSVATGSSPGITLTTYSRS-ECHVDFFRTPEEAHALSAPTS-RLSVKQLVIRRGAALGAASATLMVGLTVRILATRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38767-1", "uniprot_id": "ERC1_YEAST", "id": "P38767-1", "name": "Ethionine resistance-conferring protein 1", "aln": "MSKQFSHTTNDRRSSIIYSTSVGKAGLFTPADYIPQESEENLIEGEEQEGSEEEPSYTGNDDETEREGEYHSLLDANNSRTLQQEAWQQGYDSHDRKRLLDEERDLLIDNKLLSQHGNGGGDIESHGHGQAIGPDEEERPAEIANTWESAIESGQKISTTFKRETQVITMNALPLIFTFILQNSLSLASIFSVSHLGTKELGGVTLGSMTANITGLAAIQGLCTCLDTLCAQAYGAKNYHLVGVLVQRCAVITILAFLPMMYVWFVWSEKILALMIPERELCALAANYLRVTAFGVPGFILFECGKRFLQCQG------------------------------------IFHASTIVLFVCAPLNALMNYLLVWNDKIGIGYLGAPLSVVINYWLMTLGLLIYAMTTKHKERPLKCWNGIIPKEQAFKNWRKMINLAIPGVVMVEAEFLGFEVLTIFASHLGTDALGAQSIVATIASLAYQVPFSISVSTSTRVANFIGASLYDSCMITCRVSLLLSFVCSSMNMFVICRYKEQIASLFSTESAVVKMVVDTLPLLAFMQLFDAFNASTAGCLRGQGRQKNRWVHQPSRILLPRCAHGICVSIPVSSGCRRLMVGYN---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . * .: : * :: :: : : * . .***. ** .***. *: *::. **.:. *** :*::*. * : ***::** :: :*. :* :. *: ::::* :: : ::. *: *: : .:* :*: ::* ** * .. : .. :* * :: : :* *:. : . : : *::* : . *. :.:::* **:*.:.*: *: :*: ::: . :. *.**:: :* :.* :* .:.:.. .**. :**. .. :. :: : :: *: :. :*:.: :: :* :.:*: : ::*:.: .* *** *.* :. . *: : : . * * ", "identical_positions": 76, "similar_positions": 154, "identity": "10.19%" }, { "cls_id": "homologset.agr.SGD:S000001076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQJ2-1", "uniprot_id": "PIHD1_MOUSE", "id": "Q9CQJ2-1", "name": "PIH1 domain-containing protein 1", "aln": "MADSTFLAPELSDTESMGEETVRFQELLLKASKELQQAQTARPDSTQIQPKPGFCVKTN--SSEGKVFINICHSPSIP-PPADVTEDELLQMLE-EDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLG------SISQQNIRSQQRPRIQELGTLDASGSLGTC-----HGPERPHLNLWLEAP----DLLLAEVDLPKLDGAQGLALEIGENRLVIGGPQQ--------------LYHLDATVPLRINSEASRAAFHRRRKQLMVSMPLLTASS--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V7F5-1", "uniprot_id": "PIHD1_RAT", "id": "Q4V7F5-1", "name": "PIH1 domain-containing protein 1", "aln": "MADSKLLAPELSDAESMGEETVRFQELLLKASKELQQAQTARPESTQIQPKPGFCIKTN--SSEGKVFINICHSPSIP-PPVDVTEDELLQMLE-EDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLG------SISQQSIRSQQRPRIQELGTLDTHDSLGTR-----HGPERPHLNLWLEAP----DLLLAEVDLPKLDGAQGLALEIGENRLVVGGPQQ--------------LYHLDACIPLRINSEASRAAFHHRRKQLMVSMPLLSASS--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NWS0-1", "uniprot_id": "PIHD1_HUMAN", "id": "Q9NWS0-1", "name": "PIH1 domain-containing protein 1", "aln": "MANPKLLGMGLSEAEAIGADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTN--SSEGKVFINICHSPSIP-PPADVTEEELLQMLE-EDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMG------SISQQNIRSEQRPRIQELGDLYTPAPGRAE-----SGPEKPHLNLWLEAP----DLLLAEVDLPKLDGALGLSLEIGENRLVMGGPQQ--------------LYHLDAYIPLQINSHESKAAFHRKRKQLMVAMPLLPVPS--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RM55-1", "uniprot_id": "PIHD1_DANRE", "id": "Q1RM55-1", "name": "PIH1 domain-containing protein 1", "aln": "MDTDASLLLGVEHEQKQQEE--LYQQLLLQTMGKLQ---SDSPPSKVIRPQPGLCVKTSSVSDKKKVFLNICQSQTVP-PPPHLSQEALVELLESEDPTSYRVPMSLGEPHTEVDNSSQGCTVYDVVINDEFFQKCEKDTLFQQFLIAVSLEGLENKYSLELSRDIKILKNRKFMG------SIAEQNIRTKSKPIIQEI---DSKESLTLP-----SAAKRPEFTLLVEPPSGKAEHLIAEILLPGVSSARSLVLDLGEDRLVLIARPS--------------LFHLDIFFPVLIDQENSVAQYNTNTQTLTVTMPVVSL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38768-1", "uniprot_id": "PIH1_YEAST", "id": "P38768-1", "name": "Protein interacting with Hsp90 1", "aln": "---MADFLLRPIKQRHRNEDKYVSVDAADGSVSKIEPIADFVIKTKLLSANGPEKLQDG-----RKVFINVCHSPLVPKPEVDFNARIVFPLII---QNEWEIPIITSCYRMDHDKKGQECYVWDCCINSDCSRWICDDIQLREILVEWCLESCEIRDSVVLCRDRIAFPKMKKKGAELPALEVLNDELHQDYKAKMHKIIEEEAGDPMSILRGRNDDGDDNNDPDDGTLPPLFPIENKISGAKIEEIDKNEIAHRNLKQAPAPAPAPHEQQEDVPEYEVKMKRFKGAAYKLRILIENKAPNSKPDRFSPSYNFAENILYINGKLSIPLPRDIVVNAADIKIFHIRKERTLYIYI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : : ::: :. : .: :: . ***:*:*:* :* * ... :. :: :.:*: . : : * ..* * .:* :*.: .. :::::: . *. * : .: * : : * .: ::.:: . :. :::: : . . .. . .* : :: : :. :: : . . : . : *:.. . : . .: :: ", "identical_positions": 20, "similar_positions": 102, "identity": "5.63%" }, { "cls_id": "homologset.agr.SGD:S000001077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15436-1", "uniprot_id": "SC23A_HUMAN", "id": "Q15436-1", "name": "Protein transport protein Sec23A", "aln": "MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPLTQATRGPQVQQPPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQG-KRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDN--AKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMG-DSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGRGAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38769-1", "uniprot_id": "NEL1_YEAST", "id": "P38769-1", "name": "GTPase-activating protein NEL1", "aln": "---------------------------------MCSPTNFLYEPFS--SDAVTQNYDQNLKC-TKCGAYYSMACSLRE-QNVWTCLFCNQSN-----------SNAELPLVPSN-TYTLTSAKKEILSRRTIMIIDAICDPHELNYLVSILCNNYITRQQEPLS-------IITIQQSGHVILHNAVNHRRDAVFSINEFMTKYNLDKLNASYFEK--KISEINQESYWFD--KSTQGSLRKLLREICKIANKVNISSKRDKRCTGLALFVSSVLASQCSLSAYCHIVSFLNGPCTKGGGKVMSRERGESMRQNHHFESKSSQLQLSKSPTKFYKKMLEKFANQSLIYEFFIASLDQIGILEMS--PLITSSMAVSQFDSFNDERFAMSFQKYLNLRDHNAIYNCHSKIMTAKNAIVVKDF----PKYSLNPK--------------------------NLSLPLEISLGHNS-----AEAPIQFQTTFENQT-EKYIRIETLLLPKANRSFGAQNEIVFSMKKIASRIIDSFAYSSKHTKE-------LMKQLFLLPNQIRGKDVDMVN----------LIQWCYHIYRSPILSVRNTSPDERYLFLHRIINASKDTCLSLCKPFIWSYSDLK-HDWIVLDVP---LTRAQILQDDKTTICVDGGSYLVLRRGKLLEKEGRELCCKLLND---------LQRFPQPLYVETKTGGSQDRFLKSKIIPLDITD---------KETLGTEDMTFNEYFNLFTDLSGSK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. *: *:. .* . :*: * . *.* * . *.: ::*:* ** * * * *:*. : . : :. : ::*: : .:*: * . : . .* :: ::: * : :: .* :* ::: .*.*: : : ::.: .. ::: :. : .* .** *: : . * . ** *.:*:** :: * . .: .:*: *:.**.*:* * *:. * .:*. *.::... : *. **.:: : :: *. . : ::: .:*** *:***. * :*.. * **** . * :**: :. *. : .. : *.: :* * ***.* .*:: :*: **: ....*** * :::.: :: **: *: *: . ** . :: *: :: :* .*:* * :**: * ::: . * . *: :*: **.:*.* *.**** : *:::. . .* : :*::::** : ::** . * ::: : .* : *:. : * :**: .*** * *::*: **** *** **: * : : .: *:*:::: ::: :..*: *. ", "identical_positions": 148, "similar_positions": 226, "identity": "19.25%" }, { "cls_id": "homologset.agr.SGD:S000001079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LED7-1", "uniprot_id": "A0ABK0LED7_RAT", "id": "A0ABK0LED7-1", "name": "Multifunctional fusion protein", "aln": "---MLPPALLRRSLLSYAWRGSGLRWKHASS-------LKVANEPILAFT-QGSPERDALQKALNDLKDQTEAIPCVVGDEEVWTSDVR---YQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPVADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISV--PPSTNHVVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNVIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDR--FRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPQSLWPQIKG---RLLEEHSRIKVGNPAEDFG-----TFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYFVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDEKYRETLQLVDSTTSYGLTGAVFAQDKTIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGEWRVPGQPRLVQLWTEPPFTPLAVSPPLGDWRYSYMQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHT0-1", "uniprot_id": "AL4A1_MOUSE", "id": "Q8CHT0-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "---MLPLPSLRRSLLSHAWRGAGLRWKHTSS-------LKVTNEPILAFS-QGSPERDALQKALKDLKGQMEAIPCVVGDEEVWTSDIQ---YQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISV--PPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDR--FRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKG---RLLEEHSRIKVGDPAEDFG-----TFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKP-LGDWRYSYMQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30038-1", "uniprot_id": "AL4A1_HUMAN", "id": "P30038-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "--MLLPAPALRRALLSRPWTGAGLRWKHTSS-------LKVANEPVLAFT-QGSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQ---YQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISV--PPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDR--FHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKG---RLLEEHSRIKVGDPAEDFG-----TFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKP-LGDWSYAYMQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY23-1", "uniprot_id": "AL4A1_DANRE", "id": "Q7SY23-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "-------MLRARSAVSQSWKG--FKTFSCVA-------VEVKNEPVLEFK-EGSKERAELEEALRNLKGKTEEIPCVIGNEEVWTKDIR---FQLSPFNHSHQVAKFCYADKDLLNKAIEASVAARREWDLKPVSDRAQIFFKAADIISGPKRAEVLAKTMIGQGKTVVQAEIDAAPELIDFFRFNAKHAIELEDQQPLDS--DGSTNTMLYRGLEGFVAAVAPFNFTAIGGNLAGTPALMGNVVLWKPSDTAMSASYAVYKILRESGLPPNIIQFVPADGPVFGDTVTSSEHLAGINFTGSVPTFKRLWKQVAQNLDI--YKNFPRVAGECGGKNFHFVHKSADVRSVVTGTIRSAFEYGGQKCSACSRMYVPDSLWPQIRQ---GLLDVYKQIKVGDPVEDFS-----TFFSAVIDDKSFSRIKGWLEHARSSPHLKIIAGGNCDDKKGYFVEPTIIETTDPQEKIMNEEIFGPVLTVYVYPENDYKKVLHLIDNTSPYALTGAIFPQDKSVIEEAGKALRNAAGNYYINDKSTGSIVAQQPFGGARASGTNDKPGGPHYVLRWTSPQVVKQTHVP-LTEWKYPYMS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX4-1", "uniprot_id": "Q9VNX4_DROME", "id": "Q9VNX4-1", "name": "Multifunctional fusion protein", "aln": "MLRMMRSSSSRCSSLQQSLLKSSTRCLGSVIPDLKLKDFPIANEPILGYL-KDSKERKALEQALKGTASSCEDIPIVIGGKEYKTPEVR---YQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDN--YVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKE---GLVCEAAKLKIGD-VQDFS-----SFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIKETFVP-LRDVNYPYMCE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07275-1", "uniprot_id": "PUT2_YEAST", "id": "P07275-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "---MLSARCLKSIYFKRSFSQLGHIKPP----------KHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVES-ADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE-LTDFKYPSNYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : ***: : . : *. :* . :* *:..:. : : * * :* : :*.. * : : .*:.:: :: .* .. ** :: ****::: * :: * **:**.*.. *****. .** **:* . . :: **:. : * ** ::**: *::*******..** :****** *:****:** :.: : ::.*:*:* .:::*:*.* . * : :. .: .::****. .*: *: :: ..: : :**: ** ******::* **:: .* .*:*.:**: ******.**:*:*.* :: :: : :. .. :. * ..**. ::* :: :*.*:..* * *: ** ... *::* * :: :. *.. *. *:***:*::* * : . : .::..:: :.****:* :*. :: * . :: :***:*****.**::*.** ***.* ** .* *. : :.. * : *. ", "identical_positions": 162, "similar_positions": 192, "identity": "27.46%" }, { "cls_id": "homologset.agr.SGD:S000001080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKI9-1", "uniprot_id": "RRFM_RAT", "id": "Q5RKI9-1", "name": "Ribosome-recycling factor, mitochondrial", "aln": "MALGIRCFRLLHPAFSSYLADLSRPVSEVPMKTVRGRQRDHIQYSAHPAVPVRQFATKKAKAKGKGQPQARVNINTALVEDIISLEEVDEDMKSVMEALKDNFNKTLNIRTAPGSLDHITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPE---VEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMN--KLKKSKDKTSEDTIRLIEKQISQMADDTVAELDRHLAAKTKELLG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6S7-1", "uniprot_id": "RRFM_MOUSE", "id": "Q9D6S7-1", "name": "Ribosome-recycling factor, mitochondrial", "aln": "MASGIRCFRLLHPAFRSYHAALTRPVSEVSMKTVSGRQHGHRQYSAYPAVPVRHFATKKAKAKGKGQPQARVTVNRALVEDIISLEEVDEDMKSVVEALKDNFNKTLNIRTAPGSLDHITVVTADGKVALNQIGQISMKSPQVILVNMASFPECTAAAIKAIRESGMNLNPE---VEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMN--KLKKSKDKTSEDTIRLIEKQISQMADDTVAELDQHLAAKTKELLG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E11-1", "uniprot_id": "RRFM_HUMAN", "id": "Q96E11-1", "name": "Ribosome-recycling factor, mitochondrial", "aln": "MALGLKCFRMVHPTFRNYLAASIRPVSEVTLKTVHERQHGHRQYMAYSAVPVRHFATKKAKAKGKGQSQTRVNINAALVEDIINLEEVNEEMKSVIEALKDNFNKTLNIRTSPGSLDKIAVVTADGKLALNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPE---VEGTLIRVPIPQVTREHREMLVKLAKQNTNKAKDSLRKVRTNSMN--KLKKSKDTVSEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSW4-1", "uniprot_id": "Q9VSW4_DROME", "id": "Q9VSW4-1", "name": "Ribosome-recycling factor, mitochondrial", "aln": "--MLRSALHLAALGVRQTRVSSSSPK----LPLILQNNLENTKYLQVARDYAKGKDKKKEKG-GKGKP-GKVEINEQQLREILNFDGLNSQMQKSVMQMKEDFVKHLSLRSTSGAIDTLRIKVDGQEHELQELAQISRKNPKTIIVNMIGFPQTIPDVLKAIEKSGMNLNPQ---QDGTTLFIPIPKVTKEHRENLSKNAKALFVKYRDAIRGVQNEHIR--KLKKQPE-LGKDDAFAAQAQVTAIADRFISEADKLLASKQKELLGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38771-1", "uniprot_id": "RRF1_YEAST", "id": "P38771-1", "name": "Ribosome-recycling factor, mitochondrial", "aln": "---------MILTTARLNCRPVTVPR-------------------LFNRSFSQSFIILKKKS---STPTEKVEEDEIDVNELL--KKAETQFKKTLEIQKQKMNEIKQGNFNPKVFNSLVFKN---NRKFTDIATTSLKGKNALLITVFD-PKDVKTVISGVLAANLNLTPERVPNNDLQLKVSLPPPTTESRLKVAKDLKRVFEEYKQSSLKDSLGTIRGSILKEFKSFKKDDAVRKAERDLEKLHKDYVNKLHDQFQKVEKSIVK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * *. . . :* : :.::: . : :::. : *:.: : . . . :: : . : : ::. * *. : :::.: . *: .:..: :.:**.*: :. : :.:* * * * : * * : :: :. **: . .* : :: : . : : . : *.:: ", "identical_positions": 21, "similar_positions": 81, "identity": "7.84%" }, { "cls_id": "homologset.agr.SGD:S000001082", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC05-1", "uniprot_id": "B1WC05_RAT", "id": "B1WC05-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAEKEGTPGGGPQRVAEGARPRPAAGGEGAGDLGGSPEADDGEERNGLTGIKTTED--------AEEIKMDLAVVKQEVVDWSDLDGDISDSHWVKQEVEGGPEVKAE-KDVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEAKEE--DLNVKQ-ELFVGQNVKEEQVMDRVPVKEEDCFKREVTEDTKVKEEPQMNPRVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKRHKAELMCSG-VRDKTAYVSLQRFTEMN---------LLSDYRFLEDVARTADRVSRDIFLTRPKRK-----KYLLFLKN---------------RARKQGVYLRLLPSGFSKRRENSTVFDHRNQQFCWHVKLQFPQSQAEYVEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYTQS---------QTGVQILMRVENMQQNLIRYYELDPSKSLVNNLRNKVIIEYPTLHVVLKGCSNDMQLLHQVKSESAQKLGNGD---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFB2-1", "uniprot_id": "BCD1_MOUSE", "id": "Q3UFB2-1", "name": "Box C/D snoRNA protein 1", "aln": "MESAAEKEGTPGGGSQRVAEGARPRPAAGGEGARDLDGSPEAGDGEERNGLAGTKTTED--------AEEIKMDLAVVKQEVVDWSDLDSGVADSQWVKQEVEGGPEVKDE-KGVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEVKEE--DLTIKQ-ELFVGQNVKEEQVMDAAPIKEEGSLKSEAMEDAKVKEEPQMNPRVGSKRKLALSRCETCGTEEAKYRCPRCMRFSCSLPCVKKHKADLTCSG-VRDKTAYVSLQQFTEMN---------LLSDYRFLEDVARTADKVSRDTFLKRPKRK-----KYLFFMKN---------------RARKQGIYLRLLPNGFSKRKENSTVFDHRKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEESDPVIRQRLKAYAQS---------QTGVQILMRVENMQQNMIRYHELDPYKSLSDNLKDKVIIEYPTLHVVLRGSSNDKQLL-QVKSESAQKLGNGN---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWK9-1", "uniprot_id": "BCD1_HUMAN", "id": "Q9NWK9-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDGEEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAG-QWVEQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGEPEVKEE--KVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGECVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNG-VRDKTAYISIQQFTEMN---------LLSDYRFLEDVARTADHISRDAFLKRPISN-----KYMYFMKN---------------RARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRS---------QTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIB7-1", "uniprot_id": "A0AB32TIB7_DANRE", "id": "A0AB32TIB7-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMNLPDVDNNTADEERRAVKRKMAMSRCDVCDCEEAKYRCPSCKKHTCSLVCVKRHKSVSGCSG-VRDQTAFVSLSDFREIH---------MLSDYRFLEDSARLRQQSSRDTVMTSGRQHP----KQGQWMIR---------------KAKAVKVTLKLLPKVFSKHRENTTVFIHRERRFHWHLNIHFPQSEAVYSERR-PDNTPLEQILHGYIHPSEADPVRRQKLKLYVSS---------QQNIRVFLKAELEQLNSLRYHELELNKTLQENLMYKTIIEYPELFVVLDQHSQQYHTPEPDAPDEGTASASSSPSETPAKKKPRVSEDEDLEDGELRSEDDEENQHHTQNKLAEDAERTAGPPEEEHKPSGESERAHDDDDDDDEGQTDRPRPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38772-1", "uniprot_id": "BCD1_YEAST", "id": "P38772-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTHDPKEYISSEALKQADDDKHERNAYVQRDYNYLTQLKRMVHVQKMDARMKNKRVLGPVGGHNSNFKKRRYDIDEDDRDSTECQRIIRRGVNCLMLPKGMQRSSQNRSKWDKTMDLFVWSVEWILCPMQEKGEKKELFKHVSHRIKETDFLVQGMGKNVFQKCCEFYRLAGTSSCIEGEDGSETKEERTQILQKSGLKFYTKTFPYNTTHIMDSKKLVELAIHEKCIGELLKNTTVIEFPTIFVAMTEADLPEGYEVLHQEPRPLEHTSTLNKFIDNAREEEDAE-------EDSQPTEEPVQKETQDASDSDSDSDDDYNPGLSMDFLTA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*. :* **:** * :*** * *:**: *.* .:* . ::* . : : . : **.:* : * . . * :. : : . : : :**. : : :* : : : * * :: : : ::. .. . . :: .. * :: : * : : . : : * . :::: . . : * ::* . : :: .. ", "identical_positions": 34, "similar_positions": 77, "identity": "5.73%" }, { "cls_id": "homologset.agr.SGD:S000001083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE9-1", "uniprot_id": "MED20_RAT", "id": "Q5XIE9-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPTVFG--------------NRHDAVYGPAD---TMVQYMELFNKVRK--------------QQQVP-------VAGIR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0X0-1", "uniprot_id": "MED20_MOUSE", "id": "Q9R0X0-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSLQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHA-PGAPTVFG--------------NRHDAVYGPAD---TMIQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H944-1", "uniprot_id": "MED20_HUMAN", "id": "Q9H944-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPAVFG--------------NRHDAVYGPAD---TMVQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBX1-1", "uniprot_id": "MED20_DANRE", "id": "Q6DBX1-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVCQVPVAEGKSVQQTVDLLHRKLEQLGAVKQGNFWVDCETYHATGN---ATGQPSKLLYVMHNSEAPLSCMALFEGGP----GLSADANFDVLMIKLKSHFQNAKGHKVESRGTRYRYCDFLVKIGT-VAMSSSARGISVEVEYCACVIPGDCWNLMKEFMQSFLGSNT-PELPTVFT--------------NKAEGLYVPVDCMDTMSQYLELFSKVRK--------------QQVLP-------GSGVR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91641-1", "uniprot_id": "MED20_DROME", "id": "P91641-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETFISTPQP--HNGAPGRAVHVLHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKLGS-VTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQLHAKHNDIFEPMD---TVKQYLEQFTNYRKHVTLMGGMGSGPGSQQVGPNVHMSPAVAGLHRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34162-1", "uniprot_id": "MED20_YEAST", "id": "P34162-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGKSAVIFVERATPATLTELKDALSNSILSVRDP----WSIDFRTYRCSIKN--LPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIA--GIEGHLAEIR----------AKEYKTSSDSLG-PDTSNEICDLAYQYVR--------------------------ALEL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : . : . : * . : : : :* .*: : . . .: :: : . . . : :... ** ::: . . . :.:: :. ::* .: :: : : : . . . .: : * . : . . . . * : : : : : ", "identical_positions": 10, "similar_positions": 67, "identity": "3.88%" }, { "cls_id": "homologset.agr.SGD:S000001084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00388-1", "uniprot_id": "NCPR_RAT", "id": "P00388-1", "name": "NADPH--cytochrome P450 reductase", "aln": "-MGDSHEDTSATMPEAVAEEVSLFSTTDMVLFSLIVGVLTYWFIFRKKKEEIPEFS-KIQTT---APPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR-YGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDV-DLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDD-DGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQK-------PPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAK---SGRVNKGVATSWLRAKEPAGENG--------------------GRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGK------EVGETLLYYGCRRSDEDYLYREELARFHK--DGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37040-1", "uniprot_id": "NCPR_MOUSE", "id": "P37040-1", "name": "NADPH--cytochrome P450 reductase", "aln": "-MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFS-KIQTT---APPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR-YGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDV-DLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDD-DGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQK-------PPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAK---SGRVNKGVATSWLRTKEPAGENG--------------------RRALVPMFVRKSQFRLPFKPTTPVIMVGPGTGVAPFMGFIQERAWLREQGK------EVGETLLYYGCRRSDEDYLYREELARFHK--DGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16435-1", "uniprot_id": "NCPR_HUMAN", "id": "P16435-1", "name": "NADPH--cytochrome P450 reductase", "aln": "-MGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFT-KIQTL---TSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR-YGMRGMSADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDV-DLSGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDD-DGNLEEDFITWREQFWPAVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQK-------PPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETK---AGRINKGVATNWLRAKEPAGENG--------------------GRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGK------EVGETLLYYGCRRSDEDYLYREELAQFHR--DGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27597-1", "uniprot_id": "NCPR_DROME", "id": "Q27597-1", "name": "NADPH--cytochrome P450 reductase", "aln": "MASEQTIDGAAAIPSGGGDEP-FLGLLDVALLAVLIGGAAFYFLRSRKKEEEPTRSYSIQPTTVCTTSASDNSFIKKLKASGRSLVVFYGSQTGTGEEFAGRLAKEGIR-YRLKGMVADPEECDMEELLQLKDIDNSLAVFCLATYGEGDPTDNAMEFYEWITSGDV-DLSGLNYAVFGLGNKTYEHYNKVAIYVDKRLEELGANRVFELGLGDD-DANIEDDFITWKDRFWPAVCDHFGIEGGGEEVLIRQYRLLEQPDVQPDRIYTGEIARLHSIQNQR-------PPFDAKNPFLAPIKVNRELHKGGGRSCMHIELSIEGSKMRYDAGDHVAMFPVNDKSLVEKLGQLCNADLDTVFSLINTDTDSSKKHPFPCPTTYRTALTHYLEITAIPRTHILKELAEYCTDEKEKELLRSMASISPEGKEKYQSWIQDACRNIVHILEDIKSCRPPIDHVCELLPRLQPRYYSISSSAKLHPTDVHVTAVLVEYKTP---TGRINKGVATTYLKNKQPQGSE----------------------EVKVPVFIRKSQFRLPTKPETPIIMVGPGTGLAPFRGFIQERQFLRDEGK------TVGESILYFGCRKRSEDYIYESELEEWVK--KGTLN-LKAAFSRDQGKKVYVQHLLEQDADLIWNVIGENKGHFYICGDAKNMAVDVRNILVKILSTKGNMSEADAVQYIKKMEAQKRYSADVWS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16603-1", "uniprot_id": "NCPR_YEAST", "id": "P16603-1", "name": "NADPH--cytochrome P450 reductase", "aln": "------------MPFG-------IDNTDFTVLAGLVLAVLLYVKRNSIKELLMSDDGDITAVS-----SGNRDIAQVVTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFESLNDVPVIVS----IFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQEAKFTSQFQYTVLNEITDSMSLGEPSAHYLPSHQLNRNADGIQLGPFDLSQPYIAPIVKSRELFSSNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFDLKPLDP--TVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSKDKDQFAVEITSKYFNIADALKYLSDGAKWDTVPMQFLVESVPQMTPRYYSISSSSLSEKQTVHVTSIVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGPRKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNNVSLGKHILFYGSR-NTDDFLYQDEWPEYAKKLDGSFEMVVAHSRLPNTKKVYVQDKLKDYEDQVFEMI-NNGAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKTSGRYQEDVW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :. *. ::: :: :. ** .* . : .: : :. ..:. :*:*.*****.*::* :::*: : :. * ** *: *: .* .: * . : ::****** .*.* :* ::: . :. *:.:.: :*****.***.:* . .:::*. ** *: :** .** .. ::*:::*:: : .: : : :: : : : : : : . * * : :: *** .:*::*.: .*:* .. * :* *:.:..*:::*.:***:*::* * *::: .: . * :.::.* * . * *** **: :*:.:**:** ::: .* ::..: . :* * ::. . : * : : : :. *::.: * :*:: .*****:**: . **: :: :: . **:*. *: : .: . :*:.:*:*:**** :. **:**:*****:*** ***:** : :. * :*: :*::*.* :*::*..* .: : .*:: : . : :*****. *: : ::::* :. ..:*:****:.** .* . : *:: : :*.: :* : :. **. *** ", "identical_positions": 161, "similar_positions": 252, "identity": "22.24%" }, { "cls_id": "homologset.agr.SGD:S000001088", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VUW3-1", "uniprot_id": "Q9VUW3_DROME", "id": "Q9VUW3-1", "name": "Inositol-1-monophosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYRIGEEKLEVYYQVSLELVRK-CGPLFLEGFQKPKTDYEVK-SAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANA-KTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQ------PIEVSNAKKINQALVCYEISLIVVSKGRDKNVKRLYK-LASSA---TGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGA--RFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW2-1", "uniprot_id": "Q9VUW2_DROME", "id": "Q9VUW2-1", "name": "Inositol-1-monophosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAVSESKLKEYYDVALKLVLK-CGPLMQEGYQKAKTEYKVK-ADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVS-QRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGE------PIHTSKVTTIKQAVIAYEISLIHAAGVRDKNVKRLYK-MASNA---TGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGS--KFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW1-1", "uniprot_id": "Q9VUW1_DROME", "id": "Q9VUW1-1", "name": "Inositol-1-monophosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA-ASKSQIEELYDFIYPLAVR-AGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGK------PIQVSSCEHLNDANVAYEVCLLHAPKIRNKHIKRIYH-VGSNA---RRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGG--PFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW4-1", "uniprot_id": "Q9VUW4_DROME", "id": "Q9VUW4-1", "name": "Inositol-1-monophosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVSQADIEELYNFIHPLAIK-AGEILMEGYEMASKNVSIK-GDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGK------PIHVSSCESVKDANVAYEVSLLHVHSVANKHIKRIYH-VGLNA---RRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGG--PFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTW5-1", "uniprot_id": "Q7KTW5_DROME", "id": "Q7KTW5-1", "name": "Inositol-1-monophosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHN--------------------VDVEKCLEVASNLVSE-AGRLIARNNEQRQDFVCKS--NDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEESS-GAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGR------RIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEK-MAKKA---HGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGG--EFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP62-1", "uniprot_id": "Q9VP62_DROME", "id": "Q9VP62-1", "name": "inositol-phosphate phosphatase", "aln": "MVDEKLPPSKEPAERPPDQTTPGNAATRFGLEDHEATQQDARVNTLRQAEERRGSMVPPDKRAMSMKMSQARLHTINDPNRTGTHSAEATTPPAKPAVNISSRSSLVRGVAPDLPPKPQRPSDSEADLESSDVDRPSAKRKSEKALADVSTSSSEESEKRVPPAAASAPPPAQAEPQWKSIDFAASEAEPIAPPAPRPEDVPLPPPMMSSLPTDGSPDDVQSINSKLTNTDITFHPSKVFASKATNTSGMLYSDEENEPEEEEFPKLPDQFSASDLDTLFLLACREVKK-AGAIALAENKKNQEYTTKK--HTNDIVTPTDNIVEESFIKAISSRYPNHQFIAEERISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNMYTAQLGKGAQMNGE------MIRTTGQTNLSAAMVLQEYSSGSNEARNQVATENSQR-LVKKT---HAMRSIGSSAMCLAMVASGVADAFYNFGLHVWDMAAGALIVTEAGGVVMDPAGE--ELDIMSRRCLAASTDYLALELGNCLQQNYPSPRDDEPRSVNPNEYGPAPETRDFTSQTDFPDSDTPETTDTEIGGEKSATPAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8CIN7-1", "uniprot_id": "IMPA2_RAT", "id": "Q8CIN7-1", "name": "Inositol monophosphatase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPNSEEEEELVQG---------VGPWDECFEVAVQLALR-AGQIIRKALTEEKHVSTKT--SAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQ------RLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKA---HGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG--PLDLMSCRVVAAGTREMAVLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91UZ5-1", "uniprot_id": "IMPA2_MOUSE", "id": "Q91UZ5-1", "name": "Inositol monophosphatase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPSSEEEGELVQG---------VGPWDECFEVAVQLALR-AGQIIRKALTEEKRVSTKT--SAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQ------RLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKA---HGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG--PLDLMSCRVVAAGTREMAVLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14732-1", "uniprot_id": "IMPA2_HUMAN", "id": "O14732-1", "name": "Inositol monophosphatase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPSGEDQAALAA-----------GPWEECFQAAVQLALR-AGQIIRKALTEEKRVSTKT--SAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQ------RLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKA---HGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG--PLDLMACRVVAASTREMAMLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29218-1", "uniprot_id": "IMPA1_HUMAN", "id": "P29218-1", "name": "Inositol monophosphatase 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAD----------------------PWQECMDYAVTLARQ-AGEVVCEAIKNEMNVMLKS--SPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEK--SILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQ------KLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV---HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG--PFDLMSRRVIAANNRILAERIAKEIQVIP-LQRDDED----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38710-1", "uniprot_id": "INM1_YEAST", "id": "P38710-1", "name": "Inositol monophosphatase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGET---VITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : . ::** *: :* : . : :* :*.** :*. **:****:*** *::: :* . *:. :.: .*:: : *.* *.. :. : : : : : . . . :. :* * *: . ** ... :: *.** : :*: :.. ", "identical_positions": 35, "similar_positions": 62, "identity": "5.73%" }, { "cls_id": "homologset.agr.SGD:S000001089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q11011-1", "uniprot_id": "PSA_MOUSE", "id": "Q11011-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "---------------------------------------MWLAAAVPSLARRLLLLGPPPPPLLLLLSR--------------------------------------------------------------SSRRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPAEVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPS-TLQ-TGT-GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYGGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILST--LLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGATLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELHNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKTSPPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M9V7-1", "uniprot_id": "F1M9V7_RAT", "id": "F1M9V7-1", "name": "Aminopeptidase", "aln": "---------------------------------------MWLAAAVPSLARRLLLLGSPPPPLLLLLSR--------------------------------------------------------------SSSRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPTEVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPS-TLQ-TGT-GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILST--LLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKASPPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55786-1", "uniprot_id": "PSA_HUMAN", "id": "P55786-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "---------------------------------------MWLAAAAPSLARRLLFLGPPPPPLLLLVFS--------------------------------------------------------------RSSRRR-LHSLGLAA---------------------------------------------------------------MPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPS-TLQ-TGT-GTLKIDFVGELNDKMKGFYRSKYTTP-SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILST--LLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NSE3-1", "uniprot_id": "A0A8M1NSE3_DANRE", "id": "A0A8M1NSE3-1", "name": "Aminopeptidase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPERRPFVRLPTDVYPVNYGLRLKPDLVDFTFEGKLEAAVEVTQGTNQIVMNCADIDIITASFVPDGGEEINATGFNYQNEDEKVTLCFPS-TLQ-KGS-GSLKIDFVGELNDKMKGFYRSKYSS--SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDRVALSNMNVVDRKPYAEDQSLVEVKFATTPIMSTYLVAFVIGEYDFVESQSSDGVTVRVYTPVGKAEQGKFALEVATKTLPFYKDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNSHPIEVDVGHPSEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGKPIAAVMNSWTKQMGFPIIVVDQEQHG-SDRVLKISQKKFCASGPRNDEDCPNWMVPISICTSEDPSCTKTKILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSSAMLESLLPGIRDLTLLPVDRLGLQNDLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSCNLGVLSS--LLSHTDFHEDIQEFIRDLFTPIGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFREHVEG-KQILSADLRSPVYLTVLKHGDSTTLDTMLKLHKQADMQEEKNRIERVLGAIPAPDLIQRVLNFALSEEVRPQDTVSVIGGVAGSSKQGRKAAWKFVKDNWEELHNRYQGG-FLISRLIKLTVDGFAIDKMAAEVKSFFESHHAPAAERTVQQCCENILLNAAWLKRDADDIHQYLLQRKTPPV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRH1-1", "uniprot_id": "Q8IRH1_DROME", "id": "Q8IRH1-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "MYKNALKGGIRTAKQAWKLKNELGKLNLDLAKANSDFEQHLCEAARYTQSFHFLARNTPRTPLLLLKTTGDNNSSPRIVANYYRTAPVNPPKQQNPKPSGAADKTTSVKHLFRAESGHLNALISSKQFVKVQKQFYRDFSSVSLGAPLKSSDAPLLGDLCSQYRAILAHTSADVIPGQDRHHPGCNYQQIRRAHTQLLSKEQQLEQERKMAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECS-KLKPEKIVYSAENETATLEFAQ-EIP-AETQGVLHMSFTGELNDKMKGFYRSKYFGP-NGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDG--LRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENC-LWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHI--LISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNG-TELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVAINPK-GRDMAWEFFKENNKQLLERYQGG-FLLSRLIKYLIENFASEERAKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQRDREQLAIFLRDDQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37898-1", "uniprot_id": "AAP1_YEAST", "id": "P37898-1", "name": "Alanine/arginine aminopeptidase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSREVLPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHS----INSVQINYLEIDFHSARIEGVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRN-ETIKEG--KKYTTFNTTPKMSTYLVAFIVADLRYVES-NNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKDVCSVMNIWTKRVGFPVLSVKEHKNK-----ITLTQHRYLSTG-DVKEEEDTTIYPILLAL-KDSTGIDNTLVLNEKSATFELKNE---EFFKINGDQSGIFITSYSDERWAKLSKQANLLSVE--DRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFEDKELLERTLSYLLDGTVLNQDFYIPMQGIR-VHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDREIVATYLREHEYDQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* * :* : *:*:: *** *. :: : : :*. :* . ::. . . :::..** *.. : . . *.: * * ***:* ****::* ** :: ..**:*******.***:*** :**** ::*: . . **** * . .. :. . * ** *******.::.: :** .. : ***::. *. : * ** ::*::.* :::* *.: *****:*::*: :*:************* :*:* :*:. * :* .: **:***********:** ******:*:::.: . .: **:.:* *:*: ** :**:* .****** *.:..*:::*** ***.**:*::**: .::*:. * **:. ** :.: *: * *** .* .**.* :. **. **:: ***:: *. .: : :.* :: : * *: : ** :. ::.. .::::: . . : * .:.*:* . * : **. .* . : : **:** * :: :* **.:.* ::. : ** .:.** : .* * ::. *: : :..* :: .***: .:.. *: :: . . . * *. :.:* .: :.* ::: : :* : *. : ::.::: . **: *.** .*:.:.: : :. * ** : .: * * . * :.::: .:: :* * * ::. ::. : .*: : ::. * . : . ::*: *. :.* :* *:.** : : :* : : ", "identical_positions": 242, "similar_positions": 296, "identity": "22.14%" }, { "cls_id": "homologset.agr.SGD:S000001090", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NYN7-1", "uniprot_id": "S22A6_DANRE", "id": "Q6NYN7-1", "name": "Solute carrier family 22 member 6", "aln": "-MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHCQPHANLSMSS-TDAVDVLRATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESMAETETQSCEDGWFYNMTEMSSTIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTG-TGYCYT---TGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKNPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAKIIVTICMSMLGRRPSQCGALVLAGIMILINLLVPSDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFAFFLPETLSQPLPDTIQDIDDRGLARTNS--KRLPEKLDLAMKDPS-CVLLKESV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YVM2-1", "uniprot_id": "A0A8M6YVM2_DANRE", "id": "A0A8M6YVM2-1", "name": "", "aln": "MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYG--------INTTTSCIDGWVYKAPKDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTIL-SHCFFA---IGLMLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLDKMEAEN--------TAKSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPLIQRFGRRICQSVVLLLGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQDHTDIPADESMTVTEVKLERWGRRRGWDRERST-SQDFKSGRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PJE3-1", "uniprot_id": "A0A8M9PJE3_DANRE", "id": "A0A8M9PJE3-1", "name": "", "aln": "MGNYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRVDVNLTEDWLEASAPTETLSN---GDLQVSQCWRYSLQTLTNLSGQGYSP-GQINITDIPRERCEDGWVYSADVYHSTIVSEWDLVCDSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYC---VGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAPEVIFKQSQIKEAAFQ-----KSKYSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLVIGGGFLLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQMQKS---------RSFPGRDKQSVEDGGGGEKMREEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38776-1", "uniprot_id": "YHK8_YEAST", "id": "P38776-1", "name": "Probable drug/proton antiporter YHK8", "aln": "-------------------MVAEFQIASAQSSALTSTEEEHCSINSDKAAKLDLELTSERKNDGKQSHEVTFNEDIADPEDIARHMSTARRYYISS-----------LITFTSMVITMISSSWTLPSTHIIEHFHISHEVSTLG---ITLYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFGSAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIGGALYHQSYKWTFITLLITSG-CCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAVLEVTREQTSLLSAIFLSTKRPFGLLLRDRMMGVLCFYTG--LELAIIYLYFVAFPYVFKKLYNFGPMEIACSYIGIMVGMILSAPTCLLFQKTFEWRVKRNNGVKTPEMRFEPLFYGAFLTPVGLFIFAFTCYKHVHWIAPIIGSAIFGSGVYFVFTGVFAYTVDAYRRYAASGMACNTFVRCIMAGVFPLFGLQMYKSMGVNWAGFLLAMVTVAMIPVPFLFTKYG--------ARLRAKSPYAWDD------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : .. * : . . : . . : :: .:.: : : * :*.:. . ::: :**: : : : :* . . * .: : : : : : * :: : . .* : :: . : : *: : :: : . . . :.:: : ::: : : : :: . .. : *: . . : : .: :: . :* .. . : .. * . :* . . :* . : . : . ", "identical_positions": 15, "similar_positions": 107, "identity": "2.63%" }, { "cls_id": "homologset.agr.SGD:S000001091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WZ82-1", "uniprot_id": "OVCA2_HUMAN", "id": "Q8WZ82-1", "name": "Esterase OVCA2", "aln": "------------------------MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGR-AELVCLSGPHPVPDPPGPE-GARSDFGSCPP-EEQPRGWWFSEQEADVFSALEEPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALG-QAGDPRFPLPRFILLVSGFCPRGIGFKES-------------ILQRPLSLPSLHVFGDTDKVIPSQESVQLASQFPGAI--------TLTHSGGHFIPAAAPQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7E3-1", "uniprot_id": "OVCA2_MOUSE", "id": "Q9D7E3-1", "name": "Esterase OVCA2", "aln": "------------------------MAARQTLRVLCLAGFRQSERGFREKTGALRKTLRGR-AELVCLSGPHPVPEAAAPE-GSCPDSGPCSP-EEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGAALAAYVCALG-QAGDPRFPLPRFIILVSGFCPR--GLKEP-------------ILQSPMSLPSLHVFGDTDRVIPSQESMQLASRFLGAV--------TLTHSGGHFIPAAASQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q503Y4-1", "uniprot_id": "OVCA2_DANRE", "id": "Q503Y4-1", "name": "Esterase OVCA2", "aln": "------------------------MSA-VPLRILCIHGYRQNGNSFREKTGALRKLLKKQ-VELVFISAPHQVPAIQEENCGTNQQSQTVSVGDEDQRGWWFSDVQARSFNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQEQKLEPDFNF-RFAILVAGFRSACLEHQRF-------------YEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDGAQ--------VLLHPGGHFVPAASSHRQTYQDFLK-RFQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDL1-1", "uniprot_id": "LOVG_DROME", "id": "Q9VDL1-1", "name": "Esterase CG5412", "aln": "MTNNDAAVEAAGSSRASSSKQQLKLEITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKY-AEFVFITAPHVAKALESAA-------EPVPE----QRSWWANK-DDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLICGLAKKKLTS--IRPEFAVLASGFLSGSLVHMSA-------------YEEA-ISIPTLHIYGQTDEIIPKEMSESLAARFKNAE--------VLEHSGGHYFPATAQQKQTFINFFQDRLQEYLEHEELQQSGNASFVDSGAEDDNDAEVAAMTAELDESD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38777-1", "uniprot_id": "FSH1_YEAST", "id": "P38777-1", "name": "Family of serine hydrolases 1", "aln": "-------------------------MTVQIPKLLFLHGFLQNGKVFSEKSSGIRKLLKKANVQCDYIDAPVLLEKKDLPFEMDDEKWQATLD-ADVNRAWFYHS----------EISHELDISEGLKSVVDHIKANGPYDGIVGFSQGAALSSIITNKI-SELVPDHPQFKVSVVISGYSFTEPDPEHPGELRITEKFRDSFAVKPDMKTKMIFIYGASDQAVPSVRSKYLYDIYLKAQNGNKEKVLAYEHPGGHMVPNKKDIIRPIVEQITSSLQEASE------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : *: *. . * :* ..:** . .: : .* . *.*: . . .:.*.: * **:.*::******.: . : . . .. :: :*: :. :.::* *. :*. * * : * . *.*** .* :. . : : ", "identical_positions": 33, "similar_positions": 59, "identity": "10.44%" }, { "cls_id": "homologset.agr.SGD:S000001092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54902-1", "uniprot_id": "NRAM2_RAT", "id": "O54902-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPEEKIPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDK-----YGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKS--RQVNRANKQEVREAN-------KYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSP-HADLFPNDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCG---------RSYHLGLTARPEIYLLNTV----DAVSLVSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49282-1", "uniprot_id": "NRAM2_MOUSE", "id": "P49282-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPKEKMPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLDK-----YGLRKLEAFFGFLITIMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKS--RQVNRANKQEVREAN-------KYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSP-HADLFPSDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLTFVFYLGWQCLIALGLSFLDCG---------RSYRLGLTAQPELYLLNTV----DADSVVSR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49281-1", "uniprot_id": "NRAM2_HUMAN", "id": "P49281-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLGPEQKMSDDSVSGDHGESASLG----NINPAYSNPSLSQSPGDSEEYFATYFN-EKISIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDK-----YGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKS--RQVNRNNKQEVREAN-------KYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSP-HAGLFPKDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDCG---------HTCHLGLTAQPELYLLNTM----DADSLVSR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41251-1", "uniprot_id": "NRAM1_MOUSE", "id": "P41251-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MISDKSP-PRLSRPSYG----SISSLPG---PAPQPAPCRE---TYLS-EKIPIPSADQG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWDGVLITIVDTFFFLFLDN-----YGLRKLEAFFGLLITIMALTFGYEYVVAHPSQGALLKGLVLPTCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKS--REVDRTRRVDVREAN-------MYFLIEATIALSVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLQNYAKIFPRDNN----TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLKDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGRMSKAITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALFAIGYLGLTAYLAWTCCIAHGATFLTHS---------SHKHF-------LYGLPNE----EQGGVQGSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70553-1", "uniprot_id": "NRAM1_RAT", "id": "P70553-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MIRDKNP-QRVNRPSYG----SISSLPS---PAPQPEPSRN---TYLS-EKIPIPSTEQ-------------------------------------------LLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWGGVLITIVDTFFFLFLDN-----YGLRKLEAFFGFLVTIMALTFGYEYVVARPSQGALLKGLFLPSCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKS--REVDRTRRGDVREAN-------MYFLTEATIALFVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLHNYAKIFPRDNN----TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGWLSKVITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALLAIGYLGLTAYLAWTCCIAHGAKFLTHS---------SHQRF-------LYGLPIE----EQEGREGSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49279-1", "uniprot_id": "NRAM1_HUMAN", "id": "P49279-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MTGDKGP-QRLSGSSYG----SISSPTSPTSPGPQQAPPRE---TYLS-EKIPIPDTKPG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVDTFFFLFLDN-----YGLRKLEAFFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLHSALVKS--REIDRARRADIREAN-------MYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNA----TVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAINLYFVVSYLPSLPHP-AYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHS---------SHHHF-------LYGLLEE----DQKG-ETSG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49283-2", "uniprot_id": "MVL_DROME", "id": "P49283-2", "name": "Protein Malvolio", "aln": "MSSNEAYHEPGAGGDGPGGSSGASGGGSQRSNQLHHQQILNETTYLKPAAKQAYFSDEKVLIPDDDSTNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDK-----YGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKS--RDIDRRQTKKVSEAN-------FYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVENMEIKGGLLALVCIFAILYILFNLYLVIHMAACMGNQRLMNSRWVQRFVLPSQNSFSIKNANSTYARIATSSDQEPEGLAGEDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38778-1", "uniprot_id": "SMF2_YEAST", "id": "P38778-1", "name": "Manganese transporter SMF2", "aln": "-------MTSQEYEPIQWSDESQTN-----NDSVNDAYADVNTTHESRR--------RTTLQPNSTSQSMIGTLRKYARFIGPGLMVSVSYMDPGNYSTAVAAGSAHRYKLLFSVLVSNFMAAFWQYLCARLGAVTGLDLAQNCKKHLPFGLNITLYILAEMAIIATDLAEVVGTAISLNILFH--IPLALGVILTVVDVLIVLLAYKPNGSMKGIRIFEAFVSLLVVLTVVCFTVELFYAKLGPAKEIFSGFLPSKAVFEGDGLYLSLAILGATVMPHSLYLGSGVVQPRLREYDIKNGHYLPDANDMDNNHDNYRPSYEAISETLHFTITELLISLFTVALFVN---CAILIVSG------ATLYGSTQN----AEEADLFSIYNLLCSTLSKGAGTVFVLALLFSGQSAGIVCTLSGQMVSEGFLNWTVSPALRRSATRAVAITPCLILVLVAGRSGLSGALNASQVVLSLLLPFVSAPLLYFTSSKKIMRVQLN-RTKELSRTTDKKPVADRTEDDETIELEEMGIGSSSQERSLVSPAPEYKDMSNGMIVTVLAIIVWLIISG-------------------LNFYMLLGF-----TTGKEVHL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. *. :*: :* :..:. : * *.****.*** .*.: * . *:: *:**:.:*: **:*:**:: :* :** **::*:.*.: .*: : *:* :* :.. *:.: .: * * . . : . .:* . : ::.::** :***.:** *.:*:. *: : . : :** * :: : * *. :::::* .:: : .. : . * : : .*::. .* . :. * :: :.:* :***: :. * :**: ****. . * **. ** * . :.:. *:. : :.: ** ***. * : *** :* * . : . : .: . : . . : . * . ", "identical_positions": 89, "similar_positions": 146, "identity": "14.59%" }, { "cls_id": "homologset.agr.SGD:S000001093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11240-1", "uniprot_id": "COX5A_RAT", "id": "P11240-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLAAALRRCTAAAAAR----GLLHPVSAPSPAAAVCSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12787-1", "uniprot_id": "COX5A_MOUSE", "id": "P12787-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLAAALRRCTAAAAAR----GLLHPASAPSPAAAVCSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20674-1", "uniprot_id": "COX5A_HUMAN", "id": "P20674-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLGAALRRCAVAATTRADPRGLLHSARTPGPAVAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94514-1", "uniprot_id": "COX5A_DROME", "id": "Q94514-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLSITAR--NLASALR---------SSLVGTSSRVAAVRCL-HGTEESAEEFDKRYEKYFSREGIDGWEIRKGMNDLLGMDLVPSPKIIEAGLRASRRVNDIALAIRWLEGCKDKCGDQKATLYPYLLEKITPTLQELGIPTIEELGYDKPELALKSVYDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00427-1", "uniprot_id": "COX6_YEAST", "id": "P00427-1", "name": "Cytochrome c oxidase subunit 6, mitochondrial", "aln": "MLSRAIFRNPVINRTLLRARPGAYHATRLTKNTFIQSRKYSDAHDEETFEEFTARYEKEFD-EAYDLFEVQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENED--QYKAYLDELKDVRQELGVPLKEELFPSSS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. : : : : .*: *** *: . *. * :*::: :* . *:** * :*: .***.**:**:. ::* :* * * .. * :::: . :***:. *** .. ", "identical_positions": 34, "similar_positions": 39, "identity": "21.12%" }, { "cls_id": "homologset.agr.SGD:S000001094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVY0-1", "uniprot_id": "RL1D1_MOUSE", "id": "Q8BVY0-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "-MKGSASESPSASVAEATTTDVQVTPTALLQLDREQIRKAVEVISNRSKSKKNNNE---------LLLSGSENLFLMVILWKIPEKELR----------------VKVPLPHSILSESSDVCLFTKDEFDS-PEQTEGFYKKLLKKHGVNTISQIIPFKTLKTEYKAYEAKLRLLGSFEVFITDARIRRHLPSHIG-RHFYQRKKVPVSVNLLA------KNLSKEINRCITGTVLNISKRGSCSTIRIGHTGMETEHIVDNILAVSEMLSEKLPEKWQSVKLLFLKTEKSVSLPIFSSFVTSQDEN-AVSLRSLRKQELKKRKRE-NAKLKKESKMLRKKSKKATSLLTQSGLAS---SAPAKSPGAQKKKTNKAHKKQ--------KVTEECEEAIPQLVPIG-ETPDKENVKMQENITGKTPKSKS-DPSTPKGKKRKALLATETPEASAPGTSGKK--------------------QKKDVQEFRKPEASSFSTPRKSGKKASNTPR--DKKTKAAHSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76021-1", "uniprot_id": "RL1D1_HUMAN", "id": "O76021-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "-MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYG---------LLLNENESLFLMVVLWKIPSKELR----------------VRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNKHGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIG-RHFYQRKKVPVSVNLLS------KNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R8M8-1", "uniprot_id": "F1R8M8_DANRE", "id": "F1R8M8-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "-----------MLFLLFRHTCSMETPRDELTIDQSQVKKAAQALQAFIKNSTSSQK---------LFQNDGQPISLLFTLWKIPKKEQT----------------IRIPLSHGLRTESGDVCLFTRDEPNMTAEQTERFYKKLLTERGVKNVTEVIPFKALRTEYKPFEAKRKLLGNFDLFLSDARIRFRLPSQIG-KHFYERKKAPLSVDLES------KHLARDMERLIQGTTLTVSTKGPCCMARVAHSEMTADQIVENVISAVSTISAKLASTGKNIKIIHLKSQTSVALPIYTSDLS------HLALVEEAQKKAR---------LTKGAQKRKRK---------------------TENTEAPKPVTKETEEEK------------DSEEEIPQLVPIE--TPKKK--------------------TKREGLSKKGLKKVPKPAAGNSVKKSVK-----------------------DKKLVKK-------TPKRTERGLE------KKKLKTNKT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38779-1", "uniprot_id": "CIC1_YEAST", "id": "P38779-1", "name": "Proteasome-interacting protein CIC1", "aln": "MAKKSNSKKSTPVSTPSKEKKKVIEKKSSTAIPRERVIKAVNELIKFTSKPQDENNEEGNNGKKNLLEDDEEELKKDLQLIVVNNKSFTGTSKSFKLKLLNVKHSFYKPWKEASATAVKDFKVLLILKDSDIKKVSEDDLFDQLDSEGIK-VDEIICGKDLKTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPRGTTLNVHLGNLEWLRP---EEFVDNVELISEQLIKAYQ-IRSIFIKTNRSPVLPLYYNQDV------------------------------------------------------------LDELEAKKDKIEETHEDD----------MVTIDGVQVHLSTFN------------------------------KGLMEIANPSELGSIFSKQINNAKK------------------------------------RSSSELEKESSE-----SEAVKKAKS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :.:: **.: : .. .. *: . : : . * : .*. . . .. : *. :: : . : :* . * ..*:: : ::* : *:. **.:**: ::..*..:::* * **. :* : : : :..*:*: : . *:.::: . *. ::.: ::.: . :* :* . : :: :.:*:: * **:: . .. : * : :.. : :* .: .* . . . . . . . :. . : . : * :: ", "identical_positions": 35, "similar_positions": 125, "identity": "6.69%" }, { "cls_id": "homologset.agr.SGD:S000001099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30412-1", "uniprot_id": "PPIC_MOUSE", "id": "P30412-1", "name": "Peptidyl-prolyl cis-trans isomerase C", "aln": "----MSPGPRLLLPAVLCLG--LGALVSSSGSSGVRKRGPSVTDKVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATGEKGY-GYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPT-WLDGKHVVFGKVLDGMTVVHSIELQATDGHDRPLTDCTIVNSGKIDVKTPFVVEVPDW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FHM1-1", "uniprot_id": "F7FHM1_RAT", "id": "F7FHM1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "----MSRGPRLLLPAVLFLG--LGGLVSSSGSSGVRKRGPLVTDKVFFDVRIGDKDVGRIVIGLFGKVVPRTVENFVTLATGEKGY-GYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPA-WLDGKHVVFGKVLDGMTVVHSIELQATDDHDRPLTDCTIVNSGKIDVKTPFVVEVPDW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45877-1", "uniprot_id": "PPIC_HUMAN", "id": "P45877-1", "name": "Peptidyl-prolyl cis-trans isomerase C", "aln": "----MGPGPRLLLPLVLCVG--LGALVFSSGAEGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGY-GYKGSKFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPT-WLDGKHVVFGKVIDGMTVVHSIELQATDGHDRPLTNCSIINSGKIDVKTPFVVEIADW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24369-1", "uniprot_id": "PPIB_MOUSE", "id": "P24369-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGF-GYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTS-WLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPFAIAKE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24368-1", "uniprot_id": "PPIB_RAT", "id": "P24368-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKGF-GYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTS-WLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVIIVDCGKIEVEKPFAIAKE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23284-1", "uniprot_id": "PPIB_HUMAN", "id": "P23284-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGF-GYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTA-WLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W227-1", "uniprot_id": "Q9W227_DROME", "id": "Q9W227-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "--------MKLFLSVFVVA------LVAGVVVADDSK-GPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGE-GYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTS-WLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTLPVSEAFSVAKADATD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23285-1", "uniprot_id": "CYPB_YEAST", "id": "P23285-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "---MKFSGLWCWLLLFLSVN-----VIASDVGELIDQDDEVITQKVFFDIEHGEEKVGRIVIGLYGKVCPKTAKNFYKLSTTTNSKKGFIGSTFHRVIPNFMVQGGDFTDGTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQFFITTTEEASWLDGKHVVFGQVVDGMDVVNYIQHVSRDANDKPLEAVKIAKCGEWTPELSS---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . : . :* **:**. * : .**: :**:*:. *:*..** *: :. *: .* ***:* :**:****:* *.** ****: * ****.*** * :**** * ********** : : ****:*****:::.** **. :: * .*:*: * ..* . . ", "identical_positions": 78, "similar_positions": 50, "identity": "35.14%" }, { "cls_id": "homologset.agr.SGD:S000001100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNJ8-1", "uniprot_id": "A0ABZ3NNJ8_RAT", "id": "A0ABZ3NNJ8-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MAAVDIRDNLLGISWVDSSWIPILNS--GSVLDYFSERSNPFYDRTCNNEVVKMQRLT---------------------------------------------------LEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPA--------QVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFK------DHEEQDKVKPKAKRKEEPSSIFQRQRVDALLIDLRQKFPPRFVQQKS-GEKPVPVDQAKKEAEPLPETVKSEEKESAKS---------AQQTVSTKGPPEKRMRLQSTTEKDNVTKSWGISGSCKPSDNGGHDNN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921D4-1", "uniprot_id": "MED6_MOUSE", "id": "Q921D4-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MAAVDIRDNLLGISWVDSSWIPILNS--GSVLDYFSERSNPFYDRTCNNEVVKMQRLT---------------------------------------------------LEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPA--------QVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFK------DHEEQEKVKPKAKRKEEPSSIFQRQRVDALLIDLRQKFPPRFVQQKS-GEKPVPVDQAKKEAEPLPETVKSEEKESTKN---------IQQTVSTKGPPEKRMRLQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75586-1", "uniprot_id": "MED6_HUMAN", "id": "O75586-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MAAVDIRDNLLGISWVDSSWIPILNS--GSVLDYFSERSNPFYDRTCNNEVVKMQRLT---------------------------------------------------LEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPA--------QVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFK------DHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFPPKFVQLKP-GEKPVPVDQTKKEAEPIPETVKPEEKETTKN---------VQQTVSAKGPPEKRMRLQ-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQ63-1", "uniprot_id": "MED6_DANRE", "id": "Q6IQ63-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MATVDLRDNLLGISWVDSGWVPILNP--SNVLEYFSERSNPFYDRTCNNEVVKMQRST---------------------------------------------------LDHLTQLVGVEYILLHTQEPILYIIRKQQRQSPT--------QVIPLADYYIIAGVVYQAPDLGSVISSRALSAVHGIQSAFDEAMSFCRYHPSKGYWWHFK------DQEEKERVKPKSKRKEEPSSLFQRQRVDTLLLDLRNKFPPTFYQTKP-GEKPVPV-EVKKEPEVPVETVKPQEERETKPPAPPAPPRPPPQTTPNKPPPEKRARVQ-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MSX2-1", "uniprot_id": "MED6_DROME", "id": "Q8MSX2-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MASRQMTNDHLRLSWHDTQMMATLSP--QTVMDYFCRKSNPFYDHMCNNETVRMQRLG---------------------------------------------------PEHLHNMIGLEYILLHVAEPILYVIRKQHRHNPS--------EATPIADYYIIGGTVYKAPDLANVINSRILNTVVNLQSAFEEASSYARYHPNKGYTWDFSSNKVFSDRSKSDKKDANSAKDENSGTLFQKQRVDMLLAELLRKFPPPIPPMLQNLQQPPPAGDDLNTARNASEMNNATGPLDIKT-----------EGVDMKPPPEKKSK-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38782-1", "uniprot_id": "MED6_YEAST", "id": "P38782-1", "name": "Mediator of RNA polymerase II transcription subunit 6", "aln": "MNVTPLDE----LQWKSPEWIQVFGLRTENVLDYFAES--PFFDKTSNNQVIKMQRQFSQLNDPNAAVNMTQNIMTLPDGKNGNLEEEFAYVDPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVREPDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANIYQSPTIFKIVQSRLMSTSYHLNSTLESLYDLIEFQPSQGVHYKVPTDTS--TTATAATNGNNAGGGSNKSSVRPTGGANMATVPSTTNVNMTVNTMGT-GGQTIDNGTGRTGNGNMGITTEMLDKLMVTS---------------IRSTPNYI---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : :.* .. : :. .*::**.. **:*: .**:.::*** :.* :: * **:* . ** :::****:* . : : *: *****.. :*::* : .::.** :.: ::*:::. . .::*.:* :.. :: .: .:: .: :. . :. . : . : .*: ", "identical_positions": 39, "similar_positions": 83, "identity": "11.08%" }, { "cls_id": "homologset.agr.SGD:S000001102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV96-1", "uniprot_id": "B2GV96_RAT", "id": "B2GV96-1", "name": "Vacuolar ATPase assembly protein VMA22", "aln": "MEVQALREELDS---KCLQLLSDLEELEAKRAALNARVEEGWLSLAKARYAMGAKSVG--PLQYASRMEPQVCVRASEAQDGPQTFRVIKANAQIPEEVGPSEAS-LRRRKGPTKTKESGSS----VVPQDPLNWFG--ILVPHSLRQAQASFRDGLQLAADIASLQTRINWGLSQLRGLQRKLKELDPGPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE99-1", "uniprot_id": "VMA22_MOUSE", "id": "Q8VE99-1", "name": "Vacuolar ATPase assembly protein VMA22", "aln": "MAVQALREELDS---KCLQLLSDLEELEAKRAALNARVEEGWLSLAKARYAMGAKSVG--PLQYASRMEPQVCVRASEAQDGPQTFRVIKADAQTPEEVGPSEAS-LRRRKGPTKTKELGSA----VVPQDPLNWFG--ILVPHSLRQAQASFRDGLQLAADIASLQTRINWGQSQLRGLQKKLKELDPGPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NT0-1", "uniprot_id": "VMA22_HUMAN", "id": "Q96NT0-1", "name": "Vacuolar ATPase assembly protein VMA22", "aln": "MAALDLRAELDS---LVLQLLGDLEELEGKRTVLNARVEEGWLSLAKARYAMGAKSVG--PLQYASHMEPQVCLHASEAQEGLQKFKVVRAGVHAPEEVGPREAG-LRRRKGPTKTPEPESS----EAPQDPLNWFG--ILVPHSLRQAQASFRDGLQLAADIASLQNRIDWGRSQLRGLQEKLKQLEPGAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38784-1", "uniprot_id": "VMA22_YEAST", "id": "P38784-1", "name": "Vacuolar ATPase assembly protein VMA22", "aln": "MSETRMAQNMDTTDEQYLRLIELLSNYDSTLEQLQKGFQDGYIQLSRSNYYNKDSLRGNYGEDYWDETYIGQLMATVEEKNSKVVVEIVKRKAQDKQEKKEEEDNKLTQRKKGTKPEKQKTQSHKLKQDYDPILMFGGVLSVPSSLRQSQTSFKGCIPLIAQLINYKN-------EILTLVETLSEQE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::*: *:*: *.: :.. *: .::*::.*:::.* . * :* .. : : * ::. ..::: .: :* * . * :** **. : : **: ** : ** ****:*:**:. : * *:: . :. :: * ..*.: : ", "identical_positions": 36, "similar_positions": 63, "identity": "18.75%" }, { "cls_id": "homologset.agr.SGD:S000001104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88796-1", "uniprot_id": "RPP30_MOUSE", "id": "O88796-1", "name": "Ribonuclease P protein subunit p30", "aln": "-----MAAFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKREIEKPIAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPAHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPVNVA-----------------------------------IERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENDGKAAVSTNCRAVFLHGETRKT----------------------------AFGIISTVKKPRPSEADDESLPVCKKAKCEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AG83-1", "uniprot_id": "A0A8I6AG83_RAT", "id": "A0A8I6AG83-1", "name": "", "aln": "-----MAAFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKREIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPSHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVALQVFISFSFIGGQVAWLSVGSVSLHMGTSFSLDRAIERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENEGKAAVSTNCRAAFLHGETRKT----------------------------AFGIISTVKKPRSSEAEDESLPACKKAKHEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78346-1", "uniprot_id": "RPP30_HUMAN", "id": "P78346-1", "name": "Ribonuclease P protein subunit p30", "aln": "-----MAVFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVSDPSHCNVLRATSSRARLYDVVAVFPKTEKLFHIACTHLDVDLVCITVTEKLPFYFKRPPINVA-----------------------------------IDRGLAFELVYSPAIKDSTMRRYTISSALNLMQICKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAALLHGETRKT----------------------------AFGIISTVKKPRPSEGDEDCLPASKKAKCEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPM0-1", "uniprot_id": "Q9VPM0_DROME", "id": "Q9VPM0-1", "name": "", "aln": "--MEQTRPFYDFSIPYNKDDSVLRALLNELVET---GYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKIEHLRKEFQDKLRILQRITILYVDVNVAHAMSVSHN-LRKFNLIAGQPKTDAALTHCCTAFNGDLITFDPVAGSRLLVNRKAYQVA-----------------------------------VRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIFSSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIYSDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLKVA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38786-1", "uniprot_id": "RPP1_YEAST", "id": "P38786-1", "name": "Ribonuclease P/MRP protein subunit RPP1", "aln": "MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTG-LKLYSRITLIIDDPSKGQSLSKISQ---AFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSC-----------------------------------VNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGS-----GNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHKP--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ..:. *:: **. :**: .:..:* : ::: *:*:: * : : . ::::* * :: : . * :: **: : .:: . . : **: :*: *. :: * *: :. . . :.:.:::.*.* :: *. .*:.* :**... . *:. . :*:.. *. . : : . *: * ", "identical_positions": 32, "similar_positions": 89, "identity": "9.44%" }, { "cls_id": "homologset.agr.SGD:S000001106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M31-1", "uniprot_id": "HSP7E_MOUSE", "id": "Q99M31-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRADVVANDAGDRVTPAIVAYS-EREQVVGLAAKQSRIRHVSSTVVKVKQILG--RSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETK----------LVNPEDVARLIFSKMKETAHSVLG-SDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLVFKLGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMMKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGFTAD---DINKVVLCGGSSRIPKLQQLIKDLFPA-VDLLN------SIPPDEVIPIGAAIEAGILVGKESTS-GDDSVMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQAPG------------RVSSVCLELYESEGKNSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVEVAS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYB4-1", "uniprot_id": "HSP7E_RAT", "id": "Q6AYB4-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRADVVANDAGDRVTPAVVAYS-EREQVVGLAAKQSRIRNISSTVVKVKQILG--RSTADPQAQKYISESKCLVIEKNGKLQYEIDTGEETK----------LVSPEDVARLIFSKMKETAHSVLG-SDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDCPTGKSNVLVFKLGGTSLSLSIMEVNSGMYRVLSTNTSDNIGGVHFTDSLAQYLASEFQRLFKHDVRGSARAMMKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAVRALLQQSGFTAD---DINKVVLCGGSSRIPRLQQLIKDLFPA-GDLLN------SIPPDEVIPIGAAIEAGILVGKESTS-GDDSVLIECSARDILVKGVDESGANRFTVLFPSGTPLPARRQHTLQAPG------------SISSVCLELYESEGKNSVKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQETGKCEAITVEVAS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VDF9-1", "uniprot_id": "HSP7E_HUMAN", "id": "Q0VDF9-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNISNTVMKVKQILG--RSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETK----------FVNPEDVARLIFSKMKETAHSVLG-SDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTAD---DINKVVLCGGSSRIPKLQQLIKDLFPA-VELLN------SIPPDEVIPIGAAIEAGILIGKENLL-VEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPLPARRQHTLQAPG------------SISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAISIEIAS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGE6-1", "uniprot_id": "HSP7E_DANRE", "id": "Q5RGE6-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHFGYTCACVAVFK-DGRADVVANDAGDRVTPAVVAYR-DTEQIVGIAAKQGRIRNAANTVVKVKQILG--RRYDDPDAQAHKEESKCIVVNKSGLPRYEIDTGETTK----------YVSPEDVAKLIFHKMKETAQSALG-SDVKDAVITVPFEFDEMQKNALRQAAESAGFNVLRLIHEPSAALLAYDIGQDSPLGKSHVLVYKLGGTSLSVTVLEVNSGVYRVLATQTDHQTGGESFTQELAQHLAAEFKKTFKQDVSGNARAMMKLMNSADVAKHTLSTLGSANCFVDSLYDGMDFECNVSRARFELICSSLFNKCIQPIKSLLEQVNLSTS---DVNKVVLSGGSARIPKLQQMIRDLFPD-VELLN------SIPPDEVIPVGAAMQAGILVGKDSLALGEDSITVDCCASDITLKEVDDSGLEVFTVLFPSGTPLPARRQHTLQGPG------------SLSSVRLQLFQAQQP--------IAQIVLGDLEPKEE-LHDVVTVLTMKRDGSLHVTCTEQSSGRSEAITIETAAAAS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38788-1", "uniprot_id": "SSZ1_YEAST", "id": "P38788-1", "name": "Ribosome-associated complex subunit SSZ1", "aln": "MSSPVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYV-GEDEYHGGQALQQLIRNPKNTIINFRDFIG--LPFDKCDVSKCANGAPAVEVDGKVGFVISRGEGKEEK----------LTVDEVVSRHLN-RLKLAAEDYIG-SAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAH-AEQFPFEKDVNVVVADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNARSLAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIAKAELDPL---DIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQARLISDYDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAKGDFLIGVYEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNANGVEIIFNINKDGALRVTARDLKTGNAVKGEL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VSI1-1", "uniprot_id": "Q9VSI1_DROME", "id": "Q9VSI1-1", "name": "", "aln": "-MWPRFGIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPD-AKLHN------SHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDES---NAKLVLGRGSVLPAKIRISLPQSE----------------------------EGKGDDVSKAAASFKLRTGESEILARLPDSTIPEDGLYQLEVEVDVDDKDGNVVPLVRLRCM-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: :* : .:* . .. . *:** *:*. : : : : * * * .. .:: : ::: . . . . . . . . : : . . : .:: : . . . . .*:::* : . * :* *::: ::* **:**:*.: : :::. . ** . :. *..*:: *:* ** : *.:.:. **:: :: : . *:: *: : *: *:. *: :*** :* *:...:.* *:* : . :: : . : : : .:: ::* *. *:* : :* .: . * .:*: . *.* :* : . . : : . :: : :*.: : :* . : : : : . . .: : . ", "identical_positions": 58, "similar_positions": 159, "identity": "10.41%" }, { "cls_id": "homologset.agr.SGD:S000001107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWX9-1", "uniprot_id": "DDX47_MOUSE", "id": "Q9CWX9-1", "name": "Probable ATP-dependent RNA helicase DDX47", "aln": "----------------------------------MAADEEPDSPSGALQT-------------------------AAEEEETKTFKDLGVTDVLCEACDQLGWAKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQCAVIVGGIDSMSQSLALA--KKPHIVIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIP-RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYLFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPVFPTQDEEVMMLTERVNEAQRFARMELREHGEKKKRKREDAGDDDDKEGAIGVRN--KVAG----------GKMKKRKGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V727-1", "uniprot_id": "G3V727_RAT", "id": "G3V727-1", "name": "Probable ATP-dependent RNA helicase DDX47", "aln": "----------------------------------MAADEEPDSPTEALQT-------------------------AAEEEETKTFKDLGVTDVLCEACDQLGWAKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQCAVIVGGIDSMSQSLALKSFHVGWHLGTTPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIP-RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYLFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPVFPTQDEEVMMLTERVSEAQRFARMELREHGEKKKRKREDPGDDDDTEGAIGVRN--KVAG----------GKMKKRKGR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0S4-1", "uniprot_id": "DDX47_HUMAN", "id": "Q9H0S4-1", "name": "Probable ATP-dependent RNA helicase DDX47", "aln": "----------------------------------MAAPEEHDSPTEASQP-------------------------IVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALA--KKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIP-RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRN--KVAG----------GKMKKRKGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIF6-1", "uniprot_id": "DDX47_DROME", "id": "Q9VIF6-1", "name": "ATP-dependent RNA helicase DDX47", "aln": "----------------------MSETSEDEQTQLQTSDEEEDLGSEEEQEDEDNNHKEGDSEAALSGEDDKGSEDDAAEEQKLTWKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALLENPQRYFALVLTPTRELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLA--KKPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLP-RERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILNELAGNSFMIFCSTCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRIEHLLGKQLTLYKCEEDEVMALQERVAEAQRTAKLELKDLEDTRGGHKRGGDTHDDSENFTGARKRMKPMGGTGGGGRKSFGKKNWSKGKQKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38712-1", "uniprot_id": "RRP3_YEAST", "id": "P38712-1", "name": "ATP-dependent rRNA helicase RRP3", "aln": "MSKIVKRKEKKANDELTSLAEKIRAKALENQKKLIEAEKEGGSESDSEEDATAEKKKVLKSKSKSTVSTQ--NENTNEDESFESFSELNLVPELIQACKNLNYSKPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRLWHDQEPYYACILAPTRELAQQIKETFDSLGSLMGVRSTCIVGGMNMMDQARDLM--RKPHIIIATPGRLMDHLENTKGFSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTTYLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTYLIYLLNEFIGKTMIIFTRTKANAERLSGLCNLLEFSATALHGDLNQNQRMGSLDLFKAGKRSILVATDVAARGLDIPSVDIVVNYDIPVDSKSYIHRVGRTARAGRSGKSISLVSQYDLELILRIEEVLGKKLPKESVDKNIILTLRDSVDKANGEVVMEMNRRNKEKIARGK------------GRRG--RMMT-----------RENMDMGER--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . : : :*. ::.:*.: * :**.:* : *: ** :*** **:*:*:****:******.***:***: * . : :* :*:****** ** * *::*** :*::. :***:: : *. * : : :*****:***** ***.*: :*:********:*:*:* :*:***::* ::* *:*******.*:.*****:*.:*** **.*****: * * :.:* *:.**:::***: *::::** * *: : : : . * ::* .***::.*.:*:.:*: *** ****::****:****** **:***:***..**.****************:*::*:***:** ***.::**:*. :.: :: * : * :*: . :*:. . : . * * : : : *. ", "identical_positions": 197, "similar_positions": 135, "identity": "37.03%" }, { "cls_id": "homologset.agr.SGD:S000001108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YU8-1", "uniprot_id": "SSF1_MOUSE", "id": "Q91YU8-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRNRAQAQLRNLESYAAQPHSFVFTRGRAGRNVRQLSLDVRRVMEPLTATRLQVRKKNSLKDCVAVAGPLGVTHFLILTKTDNS--VYLKLMRLPGGPTLTFQISKYTLIRDVVSSLRR-HRMHEQQFNHPPLLVLNSFGPQGM---------HIKLMATMFQNLFPSINVHTVNLNTIKRCLLINYNPDSQELDFRHYSVKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GVGLSDSEVEP-------DGEHNTTELPQAVAGRGNMQAQQS-------------------------------AVRLTEIGPRMTLQLIKIQEGVGNGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQNQQAENLQRKQELREAHKKKSLAGIKRARAR-ADGDSDAEDPGAPPEAVGAGQPEDEEDDAEYFRQAVGEEPDEDLFPTAAKRRRQGGPLG-----KKQRGKEQRPGNKGRGQGGN--WQALKLQGRSQRGKAKPRPRATHQDS---RPASRRRN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ55-1", "uniprot_id": "SSF1_HUMAN", "id": "Q9NQ55-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTASRLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETN--VYFKLMRLPGGPTLTFQVKKYSLVRDVVSSLRR-HRMHEQQFAHPPLLVLNSFGPHGM---------HVKLMATMFQNLFPSINVHKVNLNTIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GAGLSESEAEP-------DGDHNITELPQAVAGRGNMRAQQS-------------------------------AVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGR-----KRKRWEMDR----GRGRLCD--QKFPKTKDKSQGAQARRGPRGASRDGG--RGRGRGRPGKRVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDE5-1", "uniprot_id": "PPAN_DROME", "id": "Q9VDE5-1", "name": "Protein Peter pan", "aln": "MGGK-KKVHPKTRTAAFKASEPSEIVEAPHSFVIHRGLACPYITDLTLDFRRIMEPFTASNLREKRMNRIKDFVSLSSFFHVSHMGIFNKASTQ--LSFKVVRLPRGPSLTFKVHQFTLARDVISLSKK-QMIDNDHFKHAPLVIMNNFSGDGK---------HLKLMATTFQNMFPSINLATVNIGTIRRCVLFSYNPDTKLVEMRHYSVQVVPVGLKRAVQKIVKGT------VPNLGKCNEVVDFVTK---DGYASESEAE--------DDEQSHVVLAQTLKSKGNLEDKKS-------------------------------SIKLHEIGPRLTMQLIKIEEGLLTGEVLYHDHVVKTEDEKETLRKLVEKKRKQKEQRKKEQAENRARNLKLKKDEK----WAAKRAAEGRTDSDP--------------------EDDAEYYKEEVGEEPDEELFKMEAKSSRKRPSLGGGMKYKNKRAKLDTKDKNDKSERTDKYDRKDKFDRKDKKDKFDPKNRRAKFDPKNKRAKFDHRKSRKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38789-1", "uniprot_id": "SSF1_YEAST", "id": "P38789-1", "name": "Ribosome biogenesis protein SSF1", "aln": "---MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPRLTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKKAVKDAKKQRKLERRKARAAEGGEGQGKDD---------AMSDDESSSSDSEHYG-SVPEDLDSDLFSEVE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * : . * . : : :* *.*::*:* ** .*: :: * :** * :.. : *:*: ::.::.. : :*: * * **::**:: .::* **: . :: : :.::.. :.**:::*.*. *::.: ***:**.:* ..:.:*:* .::. : :: :.:*** :.: * .* :::: : . .**: : ::: .:: . *:** * *.:. . .*:: .: . ::. :::* *:***:*::*:*::**: *:*:.*..* *:.:* ::: * : * **: :* :* :: :. .: * : : ..* *:: * * ..:** ", "identical_positions": 82, "similar_positions": 156, "identity": "15.05%" }, { "cls_id": "homologset.agr.SGD:S000001110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY53-1", "uniprot_id": "DHYS_RAT", "id": "Q6AY53-1", "name": "Deoxyhypusine synthase", "aln": "--------------------------------------------------------------------MEGTP-------------------------SGAAPSSALAAVLKHSSALPPESAQVQGYDFNRG----VDYHALLEAYGTTGFQATNFGRAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFEDWLMPILDQMVQEQN----------------TEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGSLGDMIFFHSYKNP--GLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKADAFRAEKNED----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TXU5-1", "uniprot_id": "DHYS_MOUSE", "id": "Q3TXU5-1", "name": "Deoxyhypusine synthase", "aln": "--------------------------------------------------------------------MEGTP-------------------------PGAAPSSALAAVLKHSSALPPESAQVQGYDFNRG----VDYHALLDAYRTTGFQATNFGRAVQQVNAMIEKKLEPLAVDEDHHADLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRESGINRIGNLLVPNDNYCKFEDWLMPILDQMVLEQN----------------TEGVKWTPSKMISRLGKEINNPDSVYYWAHKNHIPVLSPALTDGSLGDMIFFHSYKNP--GLVLDIVEDLRLINTQAIFAKRSGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKADAFRAEKNED----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49366-1", "uniprot_id": "DHYS_HUMAN", "id": "P49366-1", "name": "Deoxyhypusine synthase", "aln": "--------------------------------------------------------------------MEGSL-------------------------EREAPAGALAAVLKHSSTLPPESTQVRGYDFNRG----VNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQN----------------TEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNP--GLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IJA2-1", "uniprot_id": "A0AC58IJA2_DANRE", "id": "A0AC58IJA2-1", "name": "Deoxyhypusine synthase", "aln": "MPFCPCLPPAFRPLACHSDHDSGLSLKHLFAPVLTIACLTSSLNLHVDPNSVVCVTPRVTEFSLHPQLLHGSPCLKNIITAVNVHHRLQNMRIGELLMAGQAPPVARAAVLKESTPLPDNLPQIRGYDFNQG----LNHRALLQSFITTGFQASSFGLAVQEINKMIEKRLEPVQEECED----SDSRQSALGCTIFLGYTSNLISSGVRESIRYLTQHKMVDVIVTTAGGIEEDLIKCLAPTFLGEFSLKGKELRQQGINRIGNLLVPNENYCKFEDWLMPILDQMVLEQK----------------TEGTHWTPSKMIHRLGKEINNPDSVYYWAYKNDIPVFSPALTDGSLGDMIYFHSYKNP--GLVLDIVEDIRRLNSKAVFAKSTGMIILGGGLVKHHIANANLMRNGADFAVFVNTGQEFDGSDSGARPDEAISWGKIRMDASPVKVYADASLVFPLLVAETFAHNASRLIQEKKSD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSF4-1", "uniprot_id": "DHYS_DROME", "id": "Q9VSF4-1", "name": "Probable deoxyhypusine synthase", "aln": "--------------------------------------------------------------------------------------------------MSTEPSVAKDAVLKRSEALAENTPQVSGYDFNEG----LDYSKLFESYVNTGFQATNLGLAIREINRMLDCRDQPLEADQIDSHETDDFIRRRSKCTVFLGYTSNLVSSGLRETIRFLAEHRMIDCIVTTAGGVEEDFIKCLAPTFMGSFELSGRDLRERGINRIGNLLVPNDNYCKFEDWVMPLLDEMLEEQK----------------SQGTIWSPSKIIHRLGERIGDPSSIYYWAAKNQIPVFCPALTDGSLGDMMYFHSFRQP--GLVVDILSDLRRLNTMAVKAVNSGMIIVGGGVIKHHICNANLMRNGADYSVFINTASEFDGSDSGARPDEAISWGKIRKDATPVKVYAEASLVFPLIVGETFAKRHHCAGKELPRETNQV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38791-1", "uniprot_id": "DHYS_YEAST", "id": "P38791-1", "name": "Deoxyhypusine synthase", "aln": "-----------------------------------------------------------------MSDIN-----------------------------EKLPELLQDAVLKASVPIPDDFVKVQGIDYSKPEATNMRATDLIEAMKTMGFQASSVGTACEIIDSMRSWRGKHIDELDDHEKKGCFDEEGYQKTTIFMGYTSNLISSGVRETLRYLVQHKMVDAVVTSAGGVEEDLIKCLAPTYLGEFALKGKSLRDQGMNRIGNLLVPNDNYCKFEEWIVPILDKMLEEQDEYVKKHGADCLEANQDVDSPIWTPSKMIDRFGKEINDESSVLYWAHKNKIPIFCPSLTDGSIGDMLFFHTFKASPKQLRVDIVGDIRKINSMSMAAYRAGMIILGGGLIKHHIANACLMRNGADYAVYINTGQEYDGSDAGARPDEAVSWGKIKAEAKSVKLFADVTTVLPLIVAATFASGKPIKKVKN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **** * .:. : :: * *:.. : *::: . ****:..* * . :: * . : : : . . *:*:******:***:**::*:*.:*.*:* :**:***:***:*******::*.* * *:.**: *:**********:******:*::*:**:*: **. :. *:***:* *:*:.*.: .*: *** **.**::.*:*****:***::**::: . * :**: *:* :* :: * :****:***::****.** *******::*::**..*:****:*******:*****: :* .**::*:.: *:**:*. *** : ", "identical_positions": 164, "similar_positions": 111, "identity": "33.61%" }, { "cls_id": "homologset.agr.SGD:S000001111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBP3-1", "uniprot_id": "D3ZBP3_RAT", "id": "D3ZBP3-1", "name": "Exosome complex component RRP4", "aln": "-------------MALEMRLPRARKPLS--------------ESLGRDSKK-HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGALVQVSPALVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEH---------------------------------KDEE-AGGFIANL-EPVSLSDREVISRLRNCIVLLVTQRMMLYDTSILYCYEASLAH-QIKDILKPEVMEEIM--LETRQRLLEQEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBV3-1", "uniprot_id": "EXOS2_MOUSE", "id": "Q8VBV3-1", "name": "Exosome complex component RRP4", "aln": "-------------MALEMRLPKARKPLS--------------ESLGRDSKK-HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEH---------------------------------KDED-AGGFIANL-EPVALSDREVISRLRNCVVLLVTQRMMLFDTSILYCYEASLAH-QIKDILKPEVMEEIM--LETRQRLLDQEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13868-1", "uniprot_id": "EXOS2_HUMAN", "id": "Q13868-1", "name": "Exosome complex component RRP4", "aln": "-------------MAMEMRLPVARKPLS--------------ERLGRDTKK-HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEH---------------------------------KEEE-AGGFIANL-EPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEIV--METRQRLLEQEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1M9-1", "uniprot_id": "Q9W1M9_DROME", "id": "Q9W1M9-1", "name": "Exosome complex component RRP4", "aln": "-----------MSTNAAIDLALDRVDWR--------------DLAAQTEEQPRVYTPGEVLMPEAGFMRGHGTFVEDENIKSSVAGVIQKVNKLISVRPLKSRYVGEIGDVVVARVSEVQQKRWRVDTNSRLDSILLLSSVNLPGGELRRRSAEDEQMMRRYLDEGDLISAEVQNIFEEGSLSLYTRSLKYGKLSQGILVKVFPALVKRRKMHFHNLPCGASVILGNNGYIWISPTKGQ---------------------------------EEEGGEGGFAQNLNEHVPRADREVIARLRNSILALAKCKLMIYDTSIQYAYEESLRY-EAHELLQQNAIYDIG--QQTQARLRDADE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38792-1", "uniprot_id": "RRP4_YEAST", "id": "P38792-1", "name": "Exosome complex component RRP4", "aln": "MSEVITITKRNGAFQNSSNLSYNNTGISDDENDEEDIYMHDVNSASKSESDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLLNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNGYIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPSISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESIGSDILTAEKMRGNGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . : .: .. :: .**: : :. :******:. :: :**** :.:**:*:.* .** ** * ** **.*::** :***:*: ..: .::*:*.*:***** ***:* .** ** :*.****:.**** :*.:*: **:********* :* : :* .:*: * * * *:** . :*:** **:**: * ::* : : :. *:.*.* * : *. .: : : * .** *: : : :::: : : .* * :: ", "identical_positions": 100, "similar_positions": 93, "identity": "27.86%" }, { "cls_id": "homologset.agr.SGD:S000001112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JU45-1", "uniprot_id": "A0A0G2JU45_RAT", "id": "A0A0G2JU45-1", "name": "tRNA (guanine(37)-N1)-methyltransferase", "aln": "---MRILLKPFGFSR-LLQAEWCYLSES-----ILLFTLVPRLRKASTNFLLGQRQGFSTMPEAEASVRDRELFS---PPSDVRGMTKLDRTAFKKTVPIPVLKARKE-VVSRLMRALRRVALQRPGIKRVIEDPKDE--------DSRLIMLDPYRMLTSDSFEKPELSALKELDV-NPQLSQYNLELTYENFKSEEILRAVLPEG--QDVTSGFSRVGHIAHLNLRDHQLPFKHLIGQVMVDKNPGITSAVNKTSNIDNTYRNFQMEVLCGEEN-MLTKVRENNYTYEFDFSKVYWNPRLSTEHGRITELLN-PGDVLFDVFAGVGPFAIPAARKNCTVFANDLNPESHRWLLHNCKLNKVDQKVKVFNMDGKDFLQG---------------------PVREELMLRLGLSTEGKPS-----------LHIVMNLPAKAIEFLSVFRSLLDGQP-CSTER---LPIVHCYCFSK--------DSDPAKDARQRAEAVLGVCLEA----SSSVHLVRNVAPNKEMLCITFQIPTATLYRDQALGLQNDQEPPLKRQKTGSMLR----SLSEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0C4-1", "uniprot_id": "TRM5_MOUSE", "id": "Q9D0C4-1", "name": "tRNA (guanine(37)-N(1))-methyltransferase", "aln": "---MRIVWKLFGFSRRLLQVEWCHPSES-----ILLFTLVPRLRKAPSVFLLGQRQGLSTMPEIEASVRDSELFS---PPSDVRGMRELDRTAFKKTVSIPVLKARKE-VVNRLMRALRRVALQRPGIKRVIEDPKDE--------DSRLIMLDPYRMLTADSFDKAELGVLKELDV-SPQLSQYNLELTYENFKSEEILKAVLPEG--QDVTSGFSRVGHIAHLNLRDHQLPFKHLIGQVMVDKNPGITSAVNKTSNIDNTYRNFQMEVLCGEEN-MLTKVRENNYTYEFDFSKVYWNPRLSTEHGRITELLN-PGDVLFDVFAGVGPFAIPAARKNCTVFANDLNPESHKWLLHNCKLNKVDQKVKVFNMDGKDFIQG---------------------PVREELMLRLGLSAEAKPS-----------VHIVMNLPAKAIEFLSVFRSLLDGQP-CSTEL---LPTVHCYCFSK--------DSDPAKDVRQQAEAVLGVSLET----SSSVHLVRNVAPNKEMLCITFQIPTATLYRNQSLSLQNDQEPPLKRQKTGDPFSGE-PQIASDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32P41-1", "uniprot_id": "TRM5_HUMAN", "id": "Q32P41-1", "name": "tRNA (guanine(37)-N(1))-methyltransferase", "aln": "-MVLWILWRPFGFSGRFLKLESHSITESKSLIPVAWTSLTQMLLEAPGIFLLGQRKRFSTMPETETHERETELFS---PPSDVRGMTKLDRTAFKKTVNIPVLKVRKE-IVSKLMRSLKRAALQRPGIRRVIEDPEDK--------ESRLIMLDPYKIFTHDSFEKAELSVLEQLNV-SPQISKYNLELTYEHFKSEEILRAVLPEG--QDVTSGFSRIGHIAHLNLRDHQLPFKHLIGQVMIDKNPGITSAVNKINNIDNMYRNFQMEVLSGEQN-MMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLK-PGDVLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQG---------------------PVKEELMQLLGLSKERKPS-----------VHVVMNLPAKAIEFLSAFKWLLDGQP-CSSEF---LPIVHCYSFSK--------DANPAEDVRQRAGAVLGISLEA----CSSVHLVRNVAPNKEMLCITFQIPASVLYKNQTRNPENHEDPPLKRQRTAEAFSDEKTQIVSNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5G9-1", "uniprot_id": "TRM5_DANRE", "id": "B8A5G9-1", "name": "tRNA (guanine(37)-N(1))-methyltransferase", "aln": "---MAAVWRRSARLFILLQRHHSCTFTS----------------QNLNHFMRSQK------VMTDQSQTDLGLFK---PPSTVRGMTELDRSAFNQTVSVPAIRLPTN-ILNKAVKSLKKVALQRPGLKRVVEEHSEDGNADCGNIEHRLLLLDPNSITSSDSFGSDEAEALKAYSV-PQEIQSYELKLTYENFKSEEILRAVLPEG--QGVTSGFSRVGHIAHMNLREHQLPYRKLIGQVIIDKNPGITCVVNKTNTIDSTYRNFQMEVLAGESN-MVAKVRENGVLYEFDFSRVYWNPRLSTEHERIVSLLH-RGDTVVDVFAGVGPFAIPAARRGCAVLANDLNPESFRWLQHNAKLNKVDQKITTSNLDGRDFIRG---------------------PVRERLPALMKGSQK---------------IHVVMNLPALALEFLDAFKGLLDPEPDQSLSN---LPQVHCYGFSK--------ENDPQRDVVERAEASLKTNLQG----QCSVHLVRNVAPNKEMMCVSFTLPRGVLYKTHTQDRDTSEEPCPKKQKCEDSTN----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRE4-1", "uniprot_id": "TRM5_DROME", "id": "Q8IRE4-1", "name": "tRNA (guanine(37)-N(1))-methyltransferase", "aln": "---MFIVSRLKDLTIITNRLRHYF------------------------------------------RNMDVKELQ---PPSSVRGMQELQREQFRKIVQVPRLRVPES-QVQRVMPLVKKFLLKMEHLHPVR--AVDQ---------SREILLHPTPVKNWDSLPTEDLQRQKVN---AENFSFADLELRYENWSANEILKSVLPTE--EEGLTSYSRIGHIAHLNLRDHLLPYKQLIGQVLRDKLPNCRTVVNKASSIDNTYRNFQLELICGDPD-YQVETKENGVPFEFDFSKVYWNPRLSTEHERIVKMLK-SDDVLYDVFAGVGPFSIPAAKKRCHVLANDLNPESFRWLQHNAKRNKCLPNIKMSNKDGRQFIVE---------------------ELREDLLKRLCTTDTTTYG-----------IHITMNLPAMAVEFLDAFRGLYSADELAQLPTNVCYPTVHVYSFAK--------GENTKELVRQLVESNLGASLDEN--LLQGINFVRNVAPNKDMYRVSFKLSLNMLTTLKEVEVTRKRYAEEELEVATKVKCV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38793-1", "uniprot_id": "TRM5_YEAST", "id": "P38793-1", "name": "tRNA (guanine(37)-N(1))-methyltransferase", "aln": "MKIALPVFQKFNRLISSCKMSGVFPYNP--------------------------------PVNRQMRELDRSFFITKIPMCAVKFPEPKNISVFSKNFKNCILRVPRIPHVVKLNSSKPKDELTSVQNKKLKTADGNN------TPVTKGVLLHESIHSVEDAYGKLPEDALAFLKENSAEIVPHEYVLDYDFWKAEEILRAVLPEQFLEEVPTGFTITGHIAHLNLRTEFKPFDSLIGQVILDKNNKIECVVDKVSSIATQFRTFPMKVIAGKSDSLVVEQKESNCTFKFDFSKVYWNSRLHTEHERLVKQYFQPGQVVCDVFAGVGPFAVPAGKKDVIVLANDLNPESYKYLKENIALNKVAKTVKSFNMDGADFIRQSPQLLQQWIQDEEGGKITIPLPLKKRHRSQQHNDQQPPQPRTKELIIPSHISHYVMNLPDSAISFLGNFRGIFAAHTKGATDT-IQMPWVHVHCFEKYPPGDQVTEDELHARVHARIIAALKVTADDLPLNAVSLHLVRKVAPTKPMYCASFQLPANV-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : * . *: : * : . :: : : : * : : :. : ::*. *: . :: : * *: :.::***::*** : :.:: *****:*** . *: *****: ** .*:* ..* . :*.* ::::.*. : .: :*.. ::****:****.** *** *:.. .:.: *********::*..:: *:********.::* * ** .:. * ** :*: ::: * .**** *:.**. *: : . * ** : * * : . : * : .:::**:***.* * :* :. ", "identical_positions": 101, "similar_positions": 113, "identity": "17.57%" }, { "cls_id": "homologset.agr.SGD:S000001114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48450-1", "uniprot_id": "LSS_RAT", "id": "P48450-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLTRWRLHN-ELGRQRWTYYQAEEDPGREQTGLEAHSLG----LDTTSYFKNLPKAQTAHEGALNGVTFYAKLQAED-GHWAGDYGGPLFLLPGLLITCHIAHIPLPAGYREEMVRYLRSVQLP-DGGWGLHIEDKSTVFGTALSYVSLRILGIGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGLLNLYERFHS-TSLRKWAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQTWDTSFAVQALLEAGAHRRPEFLPCLQKAHEFLRLSQVPDNNPDYQKYYRHMHKGGFPFSTLDCGWIVADCTAEALKAVLLLQER--CPSITEHVPRERLYDAVAVLLSMRNSD----GGFATYETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFREYFPDHRATESRETLNQGLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHIYQNRTACAEVAQACHFLLSRQMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGLMAVRHPDISAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWALGRFSSLYPDNTLAGHI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLN5-1", "uniprot_id": "LSS_MOUSE", "id": "Q8BLN5-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLTRWRLQN-ELGRQRWTYYQAEDDPGREQTGLEAHSLG----LDTRSYFTDLPKAQTAHEGALNGVTFYAKLQAED-GHWAGDYGGPLFLLPGLLITCHISHISLPAGYREEMVRYLRSVQLP-DGGWGLHIEDKSTVFGTALNYVALRILGIGPDDPDLVRARNVLHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPEWVPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVQDYASIDWPAQRNNVSPDEMYTPHSWLLHVVYGLLNLYERFHS-TSLRKWAVQMLYEHIAADDCFTKCISIGPISKTINMLVRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQIWDTSFAIQALLEAGAHHRPEFLPCLQKAHEFLRLSQVPENCPDYQKYYRHMRKGGFSFSTLDCGWIVADCTAEGLKAVLLLQNQ--CPSITEHIPRERLCDAVDVLLSLRNAD----GGFATYEKKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALKHFHEHFPDYRAAEVRETLNQGLDFCRRKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHTYQDGAACAEVAQACNFLLSQQMADGGWGEDFESCEQRRYVQSARSQVHSTCWALMGLMAVRHPDITAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTSYRNIFPIWALGRFSNLYPDNTLAGHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48449-1", "uniprot_id": "LSS_HUMAN", "id": "P48449-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLGRWRLNC-ERGRQTWTYLQDER-AGREQTGLEAYALG----LDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAED-GHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLP-DGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHS-AHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEK--CPHVTEHIPRERLCDAVAVLLNMRNPD----GGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38604-1", "uniprot_id": "ERG7_YEAST", "id": "P38604-1", "name": "Lanosterol synthase ERG7", "aln": "MTEFYSDTIG------LPKTDPRLWRLRTDELGRESWEYLTPQQAANDPPSTFTQWLLQDPKFPQPHPERNKHSPDFSAFDACHNGASFFKLLQEPDSGIFPCQYKGPMFMTIGYVAVNYIAGIEIPEHERIELIRYIVNTAHPVDGGWGLHSVDKSTVFGTVLNYVILRLLGLPKDHPVCAKARSTLLRLGGAIGSPHWGKIWLSALNLYKWEGVNPAPPETWLLPYSLPMHPGRWWVHTRGVYIPVSYLSLVKFSCPMTPLLEELRNEIYTKPFDKINFSKNRNTVCGVDLYYPHSTTLNIANSLVVFYEKYLRNRFIYSLSKKKVYDLIKTELQNTDSLCIAPVNQAFCALVTLIEEGVDSEAFQRLQYRFKDALFHGPQGMTIMGTNGVQTWDCAFAIQYFFVAGLAERPEFYNTIVSAYKFLCHAQFDTEC--VPGSYRDKRKGAWGFSTKTQGYTVADCTAEAIKAIIMVKNSPVFSEVHHMISSERLFEGIDVLLNLQNIGSFEYGSFATYEKIKAPLAMETLNPAEVFGNIMVEYPYVECTDSSVLGLTYFHKYF-DYRKEEIRTRIRIAIEFIKKSQLPDGSWYGSWGICFTYAGMFALEALHTVGETYEN---SSTVRKGCDFLVSKQMKDGGWGESMKSSELHSYVDSEKSLVVQTAWALIALLFAEYPNKEVIDRGIDLLKNRQEESGEWKFESVEGVFNHSCAIEYPSYRFLFPIKALGMYSRAYETHTL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . * ** ***. * **: * * : .. : : * :. .. . :*.:.. ** :*: ** * * :. :* **:*: * : . ::: * :* * *::**: .. * ******* ********.*.** **:**: *.* .:**. * : ***:. * ***:**:.**:*.***:*. ** **:* * **. * * * **:*:** .::*.. **::.**:*:*.: : .*:: ::*.*. ::* *** *.:. .*: :**:. : . : : :*: : :: *..:.*.*:.::. *: :* * ***. *: * *: * :**.: **** * ** :**:* :: ** .**** : .*::** :*. : **. :**.: *** *: *:*****.:**:::::: . : . :. *** :.: ***.::* . *.*****. :. :* ***:****:**::*.*****.: : .* :*:: * ::* * * : .::* ::.* .**** ****:****. *.***: :*. *.: .: * :.*.**:*:** ******.::*.* : *::* * : .*.**::.*: ..:*: . :**: * :* .*:* *.: ****:****.*..** :*** *** :* * .:* ", "identical_positions": 269, "similar_positions": 229, "identity": "36.01%" }, { "cls_id": "homologset.agr.SGD:S000001115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A716-1", "uniprot_id": "A2A716_MOUSE", "id": "A2A716-1", "name": "Oxysterol-binding protein", "aln": "MDFQERDTPSLA--ESTQS------------------------SKPSSTQQAS-----------------ELWEVMEEP------RGRLGADDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFHSWVAQLRAHRLAQRLDMP-----SATHRKAPGTQMLTAGSAS-------------ALPGVGPRE--------------KVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPV-----IPTHQTSVTTERPKKGKRTSRMWCTQGFAKD-----------------------------DTIGRVG-----RLHGSVPNLSRYL----ESRDTSGPRGLPPP-DYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDLH-------------QGSELS--RMVVSEAPDG-------QRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHT---EFFDACEVLLS----------------------ASSSENEGSEEEESCASE-ITTSLSEEVLDIRG--ADRYQKGPCVPGIAVGPPRRRCLPAAS---------------------------GPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIH--EVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L2K0-1", "uniprot_id": "A0ABK0L2K0_RAT", "id": "A0ABK0L2K0-1", "name": "Oxysterol-binding protein", "aln": "MDFQERDTPSLA--ESTQS------------------------SKPSSTQQAS-----------------ELWEVVEEP------RGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGVLHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVSQLRAHRLAQRSDLP-----NATHRKAPGTQTLTAGSAS-------------ALPGVGPRE--------------KVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPV-----IPTHQASVTTERPKKGKRTSRMWCTQGFAKD-----------------------------DTIGRVG-----RLHGSVPNLSRYL----ESRDTSGPRGLPPP-DYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDLH-------------QGSELS--RMAVSEAPDG-------QRRLHSLSISSDTTADSFSSLNPEEQEALYRKGRELTPQLSQSSVLSLADSHT---EFFDACEVLLS----------------------ASSSENEGSEEEESCASE-ITTSLSEEVLDIRG--ADRYPKGACVPGIAVGPPRRRCLPAAS---------------------------GPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIH--EVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF2-1", "uniprot_id": "OSBL7_HUMAN", "id": "Q9BZF2-1", "name": "Oxysterol-binding protein-related protein 7", "aln": "MDFQERDPPFLP--ESAQS------------------------SKPSSAQQAS-----------------ELWEVVEEP------RVRLGTEGVMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAHRLDMPRGSLPSTAHRKVPGAQLPTAATAS-------------ALPGLGPRE--------------KVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLHRIPSAPV-----IPTHQASVTTERPKKGKRTSRMWCTQSFAKD-----------------------------DTIGRVG-----RLHGSVPNLSRYL----ESRDSSGTRGLPPT-DYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRDMH-------------QGSELS--RMGVSEASTG-------QRRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSILSLADSHT---EFFDACEVLLS----------------------ASSSENEGSEEEESCTSE-ITTSLSEEMLDLRG--AERCQKGGCVPGRPMGPPRRRCLPAAS---------------------------GPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVH--EVQGAVLSRSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWWVTNNTYWRLRAEPGYGNMDGAVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BXR9-1", "uniprot_id": "OSBL6_MOUSE", "id": "Q8BXR9-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPA--HKTSTPTHRSASSSTSSQRESRQSIHVLERTASSSTEPSVSRQLLEPEPIPLSKEADSWEIIEGL------KIGQ-TNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVR-SPRDASFHIFPATSTAESSPAANVSVVDGKMQ-PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPN-----FTDMQANCVD-ISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADI--EFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVS-----EQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLPLSQQVANESRLSMSESVS---EFFDAQEVLLS----------------------ASSSENEASDDE-SYISD-VSDNISEDNTSVADNISRQILNGELTGG-AFRNGRRTCLPAPC---------------------------PDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVN--EVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LMF4-1", "uniprot_id": "A0ABK0LMF4_RAT", "id": "A0ABK0LMF4-1", "name": "Oxysterol-binding protein", "aln": "MSSDE-KGISPA--HKTSTPTHRSALSSTSSQRESRQSIHVLERTASSSTEPSISRQLLEPEPIPLSKEADSWEIIEGL------KIGQ-TNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVR-SPRDASFHIFPATSTAESSPAANVSVVDGKMQ-PSSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPN-----FTDMQANCVD-ISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADI--EFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVS-----EQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHANLPLSQQVVNESRLSMSESVS---EFFDAQEVLLS----------------------ASSSENEASDDE-SYISD-VSDNISEDNTSVADNISRQILNGELTGG-AFRNGRRTCLPAPC---------------------------PDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVN--EVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKELLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF3-1", "uniprot_id": "OSBL6_HUMAN", "id": "Q9BZF3-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPA--HKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGL------KIGQ-TNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVR-SPRDASFHIFPSTSTAESSPAANVSVMDGKMQ-PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPN-----FTDMQANCVD-ISKKDKRVTRRWRTKSVSKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCADI--EFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVS-----EQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVS---EFFDAQEVLLS----------------------ASSSENEASDDE-SYISD-VSDNISEDNTSVADNISRQILNGELTGG-AFRNGRRACLPAPC---------------------------PDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMN--EVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJS4-1", "uniprot_id": "A0A8M2BJS4_DANRE", "id": "A0A8M2BJS4-1", "name": "Oxysterol-binding protein", "aln": "MSRHQSRTTSLE--EKVATPIHR----STAPLQKSSTPTHKSASSSSSSQRDSR-------------QEPDSWEIIEGL------RIGQ-THVQRPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSPDVFDLWVCKLRHHRLFRQNEIVR-SPRDATLRTFPPSAGAESPQNTPSSTHPKKQGKPSSFPWQLPPSCSN--------GQSKVAAWLQESEEMDKCAEELAYCQSSLLELNQLLQSLEILQRTQSAPN-----FTDMQSNCVD-LSKKEKRVSRRWRTKSVSKDAKLQQQVQS--------------LPQSHSAKVPLSASMSQVRLHSSNPNLCAELA-DFQAPVTRLTDGIDSAGDYIKLQEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLL-----DHEQ-TGQSNQIVTLRRSLSQALSQNAELKTRLNRIHSESVLSEQVVSVNIISSPDEACEPLHVGLPLSQQVSNESRLSMSESVS---EFFDAQEVLLS----------------------ASSSENEASDDE-SYVSD-VSDNISEDNASVTDNVSRQMPNGELASS-MFRNGRRPCLPAPA---------------------------PDTSNINLWNILKNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAQTDDPYERMAIVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCDSQNFTFWQDVRWKNKFWGKSMEILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTRSTTCICKLSFIKGNYWSSNVN--EVQGSVMDQEGRVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAVELNELFPEMKELLPPTDARFRPDQRFLEEGNVQMATAEKQRIEEQQRNRRKWMEENNIKHQPRFFKKVMDSNQRERWVSNSMYWELRKDPGFLKLENPELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DBS9-1", "uniprot_id": "OSBL3_MOUSE", "id": "Q9DBS9-1", "name": "Oxysterol-binding protein-related protein 3", "aln": "-MSDE-KNLGVS--QKLVSPSRS--------------------TSSCSSKQGSR---------------QDSWEVVEGL------RGEM-TYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEELFDEWVSKLRHHRMYRQNEIAM-FPRDVN-HFFSGSSVTDSAPGVFESVSSRKRS---SLSKQNSFPPGSNLSFSCG-GDTRVPFWLQSSEDMEKCSKDMAHCHAYLLEMSQLLESMDVLHRTYSAPA-----INAIQ-------------------------------------------------------VPKPFSG---PVRLHSSNPNLSTLD----FGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISVEREKLKQLM------ELDTSPSPSAQVVGLKHALSSALAQNTDLKERLRRIHAESLLLDPPAVPKPGDNLAEE-NSRDEGRALVHQLSNESRLSITDSLS---EFFDAQEVLLS----------------------PSSSENEISDDD-SYVSD-ISDNLSLDNLSNDLDNERQTLGPVLESSGEARSKRRTSLPAPG---------------------------PNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIKNLNDDSCHCKVNFIKAKYWSTNAH--EIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQRERRRVLEENGVEHQPRFFRKSSD----DAWVSNGTYLELRKDLGFSKLDHPVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM73-1", "uniprot_id": "A0A8I6GM73_RAT", "id": "A0A8I6GM73-1", "name": "Oxysterol-binding protein", "aln": "-MSDE-KNLGVS--QKLVSPSRS--------------------TSSCSSKQGSR---------------QDSWEVVEGL------RGEM-TYTQEPPAQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQTDIEREKLHGSIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEDVFDEWVSKLRHHRMYRQNEIAM-FPRDVN-HFFPGSSVTDSAPGVFESVSSRKRS---SLSKQNSFPAGSNLSFSCG-GDTRVPFWLQSSEDMEKCSKDLAHCHTYLLEMSQLLESMDVLHRTYSAPA-----INAIQ-------------------------------------------------------VPKPFSG---PVRLHSSNPNLSTLD----FGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISMEREKLKQLM------ELDTSSSPSAQVVGLKHALSSALAQNTDLKERLRRIHAESLLLDPPAGPKPGDNLAEE-ISRDESRALVHQLSNESRLSITDSLS---EFFDAQEVLLS----------------------PSSSENEISDDD-SYVSD-ISDNLSLDNLSNDLDNERQTLGPVLESSGEARSKRRTSLPAPG---------------------------PNTSSVSVWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAHMPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLRDDSCHCKVNFIKAKYWSTNAH--EIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQRERRRVLEENGVEHQPRFFRKSSD----DAWVSNGTYLELRKDLGFSKLDHPVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4L5-1", "uniprot_id": "OSBL3_HUMAN", "id": "Q9H4L5-1", "name": "Oxysterol-binding protein-related protein 3", "aln": "MMSDE-KNLGVS--QKLVSPSRS--------------------TSSCSSKQGSR---------------QDSWEVVEGL------RGEM-NYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAM-FPHEVN-HFFSGSTITDSSSGVFDSISSRKRS---SISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPA-----INAIQGGSFE-SPKKEKRSHRRWRSRAIGKDAKGTLQ-----------------------VPKPFSG---PVRLHSSNPNLSTLD----FGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM------EQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEE-NSRDENRALVHQLSNESRLSITDSLS---EFFDAQEVLLS----------------------PSSSENEISDDD-SYVSD-ISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPC---------------------------PSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAH--EIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AY80-1", "uniprot_id": "A0A8M3AY80_DANRE", "id": "A0A8M3AY80-1", "name": "Oxysterol-binding protein", "aln": "MDSVDHNQSHMSGVEKVSSGWQK---------------PSHSRSSSTASSRHSR-------------LNVKDWEVMDDCPADLTITAENIQDANTPGICEGYLMKRRKWPLKGWHKRYFVLDKGILRYTKNQHDFSRGKMHGSLDVSLAVMSVNKKARRIDLDAGDNLYHLKAKSQDLYFIWVTKLSAHRMYKKNEAAH--VHNGYLQVLSHTSNLSHKTSPMQDMGTSGSSMGENLQYVSPAVNG------------KVSAWLQTQE-PDFCGQELTRCQMELNELQRLVQKLNSLESGQTVYNGDLQRMISMQNLSLDKPKKKSAKIFGHSRTLSRVEGLGMPFRG----------------------ITKSLSS----SQLNSSSLLGTSVPS-IPDYVSTPANSPASTSPESKKLHQDICSMSLKVHASLRTAHEALAQERQRLRDTWS-----GRDLHQNTSAQLNNLCSLAELDVNS------RHTKIHKLSISSN---------SSDDSFRTVEQRKSVSSRCSSFRAPSIADSVA---EYFDACDELKC----------------------ASSS--EMSDESGLSDGS-SNSEPYEAHAMASRKYRASLSKAAAKPNTIKSTGRRTTLPAVC---------------------------PDNSHVGLMTILYNNIGKDLSRVSMPAALNEPVCLLQRLCEELEYSDLLDTANHTDDPFQRMVYIAAFAISGYATAQFRNRYKPFNPVLGETFECIREDRGFRYISEQVSHHPPISACHADSDNFSFWQDQRWKNKFWGKSLEIMPTGMVNVTLKKYGDHYEWNKVVTCIHNVLSQQRYLEHYGEVIIQNLNSSVCTCKITFVKSRYWGADAARNQVQGQVLDQTGNVIHRFGGFWHEGIFCETLPVPQCIWKPNPQPKNYLLYYGFSSFAMEMNELVPELKPLLPPTDTRLRPDQRLLEEGKVEETDKKKDEVEEKQRERRKIMAKRGEEHIPRFFRKSLDAAGREVWLTNGTYWKIRENPGFANVNNLELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38713-1", "uniprot_id": "OSH3_YEAST", "id": "P38713-1", "name": "Oxysterol-binding protein homolog 3", "aln": "METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVH------------IAPDTKTLLDYT------TKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQG-DLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPD--------------ILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYR-DKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGD--KSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLAN--ETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERR----NKGQDVEPKYFEKVSK-NEWKYITGPKSYWERRKKHDWSDIS--QLW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . ::: . : . . :: .. . : . : : :: .: : ::: * :. :: : .*: *. : : :: . : :: . : : . : : . : *: :..:. . . : . :* : .. . : .: : :: . .: : .. : : : : . *::. : *:*** : : .*. * :.: .. . :: .* : .: .:* :*:***** ::**. ***: ** :.* :**: ** * . .* : .* :* * * *****:*.**:* * * ** ::*:***:**: * ..: :: .:******:*: * .: : *: : *.: .: ::*::: .*::* .*. ::. .. .:: * * :. ::. .. : * * :.: . :*. . . :.*: *: ::**: : **.**:*:*** * ***::: : * .:*: **.** :. .::*.: . . * . * . .: .:. **", "identical_positions": 104, "similar_positions": 218, "identity": "9.99%" }, { "cls_id": "homologset.agr.SGD:S000001116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q812E8-1", "uniprot_id": "NADE_RAT", "id": "Q812E8-1", "name": "Glutamine-dependent NAD(+) synthetase", "aln": "MGRKVTVATCALNQWALDFEGNFQRILKSIQIAKGKGARYRLGPELEICGYGCWDHYHESDTLLHSLQVLAALLDAPATQDIICDVGMPIMHRNVRYNCLVIFLNRKILLIRPKMALANEGNYRELRWFTPWARSRQTEEYVLPRMLQDLTKQETVPFGDVVLATQDTCIGSEICEELWTPCSPHVNMGLDGVEIITNASGSHHVLRKAHTRVDLVTMATSKNGGIYLLANQKGCDGHLLYYDGCAMIAMNGSIFAQGTQFSLDDVEVLTATLDLEDVRSYRAKISSRNLEATRVN-PYPRVTVDFALSVSEDLLEPVSEP---VEWTYHRPEEEISLGPACWLWDFLRRNNQAGFFLPLSGGVDSAASACVVYSMCCLVCEAVKSGNQQVLTDVQNLVDE-SSYTPQDPRELCGRLLTTCYMASENSSQETHNRATELAQQIGSYHISLNIDPAVKAILGIFSLVTGKFPRFSAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGAR--GSLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQLCAERFQLPVLQAILSAPATAELEPLAD-GQVSQMDEEDMGMTYTELSIFGRLRKVAKAGPYSMFCKLLNMWKDSCTPRQVAEKVKRFFSKYSINRHKMTTLTPAYHAENYSPDDNRFDLRPFLYNTRWPWQFLCIDNQVVQLE----------RKTSQ-----TLEEQIQEHFKEPSPIWKQLLPKDP----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q711T7-1", "uniprot_id": "NADE_MOUSE", "id": "Q711T7-1", "name": "Glutamine-dependent NAD(+) synthetase", "aln": "MGRKVTVATCALNQWALDFEGNFQRILKSIQIAKGKGARYRLGPELEICGYGCWDHYHESDTLLHSLQVLAALLDSPVTQDIICDVGMPIMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWTRSRQTEEYVLPRMLQDLTKQKTVPFGDVVLATQDTCVGSEICEELWTPRSPHIDMGLDGVEIITNASGSHHVLRKAHTRVDLVTMATSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSIFAQGTQFSLDDVEVLTATLDLEDVRSYKAEISSRNLEATRVS-PYPRVTVDFALSVSEDLLEPVSEP---MEWTYHRPEEEISLGPACWLWDFLRRSKQAGFFLPLSGGVDSAASACIVYSMCCLVCDAVKSGNQQVLTDVQNLVDE-SSYTPQDPRELCGRLLTTCYMASENSSQETHSRATKLAQLIGSYHINLSIDTAVKAVLGIFSLMTGKLPRFSAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGAR--GSLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCAERFQLPVLQTILSAPATAELEPLAD-GQVSQMDEEDMGMTYAELSIFGRLRKVAKAGPYSMFCKLLNMWRDSYTPTQVAEKVKLFFSKYSMNRHKMTTLTPAYHAENYSPDDNRFDLRPFLYNTRWPWQFLCIDNQVLQLE----------RKASQ-----TREEQVLEHFKEPSPIWKQLLPKDP----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IA69-1", "uniprot_id": "NADE_HUMAN", "id": "Q6IA69-1", "name": "Glutamine-dependent NAD(+) synthetase", "aln": "MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRAS-PYPRVKVDFALSCHEDLLAPISEP---IEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQ-ISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVH--GGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLAD-GQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLE----------RAEPQ-----SLDGVD-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYA0-1", "uniprot_id": "NADE_DROME", "id": "Q9VYA0-1", "name": "Glutamine-dependent NAD(+) synthetase", "aln": "MGRKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLHSWEVLLEVMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFTAWTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTCLGYEICEELWNVRSKHIEMSLAGVELIVNSSGSYMELRKAHITSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQQFALQDVEVTLATIDLEEIRAYRVSLRSRCTAAASAA-EYPRIHCDFEMSTHSDIFKTSTPP---LNWPMHTPEEEIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQQGDAQVLHDIRQLLAD-SDYTPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQLANQLGSYHIEISIDSAVNALLSIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQLTLWVRNRP--GGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLESIIDAPPTAELEPLQENGELQQTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLSPKEVAEKVKHFFLCYAINRHKMTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEKLQPIYTPSSAQLRPSSEDLLISTQRSSHLDDSKHSSPLSSASASASIDVGISTAAVPLPGAAAPGGLSKKPSGYSKVHVNVLGKIKDRTGIPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38795-1", "uniprot_id": "NADE_YEAST", "id": "P38795-1", "name": "Glutamine-dependent NAD(+) synthetase", "aln": "MSHLITLATCNLNQWALDFEGNRDRILQSIKIAKERGARLRVGPELEITGYGCLDHFLENDVCLHSWEMYAQIIKNKETHGLILDIGMPVLHKNVRYNCRLLSLDGEILFIRPKIWLANDGNYREMRFFTPWMKPGVVEDFILPPEIQKVTGQRLVPFGDAVINSLDTCIGTETCEELFTPQSPHIAMSLDGVEIMTNSSGSHHELRKLNKRLDLILNATKRCGGVYLYANQRGCDGDRLYYDGCALIAINGTIVAQGSQFSLDDVEVVTATVDLEEVRSYRAAVMSRGLQASLAEIKFKRIDIPVELALMTSRFDPTVCPTKVREPFYHSPEEEIALGPACWMWDYLRRCNGTGFFLPLSGGIDSCATAMIVHSMCRLVTDAAQNGNEQVIKDVRKITRSGDDWIPDSPQDLASKIFHSCFMGTENSSKETRNRAKDLSNAIGSYHVDLKMDSLVSSVVSLFEVATGKKPIYKIFGGSQIENLALQNIQARLRMVLSYLFAQLLPWVRGIPNSGGLLVLGSANVDECLRGYLTKYDCSSADINPIGGISKTDLKRFIAYASKQYNMPILNDFLNATPTAELEPMTK--DYVQSDEIDMGMTYEELGVFGYLRKVEKCGPYSMFLKLLHQWSPKLTPRQISEKVKRFFFFYAINRHKQTVLTPSYHAEQYSPEDNRFDLRPFLINPRFPWASRKIDEVVEQCE--------------------AHKGSTLDIMSID----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :*:*.. *********** ***:** ** ** * *****: **.* **: * *. *** :: :: ..:: *:***::*:** *** : :: :**:****: :.::***** *:**.* :. .*::.** : . * *. *****.*: : ***:* * ****:. * *: *.* ***::.*:***: *** : **: .: : ** ** :* :****. :*::**: **:** :.*:. **:*:**** **:***::*:*:. : ** *: . : *: . :: . : . * : * *****:******:**:*** **:******:**.::* :::*** : :*.:.*: :*: *:: : . .: *:.. *..::: :*:*.: ***:** ** .*:: :**:*:.:.:*. *.:::.:*. ** * : **. :******:*:*:****:*:**** * *. *.***********.* ********************* **: *: . .::::* *: :: *..******: . : * ** ****** **. :* *** ****** :*: * :* ::::*** ** *::**** *.***: ***.***:***** **** .. :.* *:: . : : : ", "identical_positions": 314, "similar_positions": 202, "identity": "39.55%" }, { "cls_id": "homologset.agr.SGD:S000001117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZT2-1", "uniprot_id": "PPME1_RAT", "id": "Q4FZT2-1", "name": "Protein phosphatase methylesterase 1", "aln": "-MSALEKSMHLGRLPSRP----------------------PLPGSGGSQSGAKMRMGPG--------RKRDFTPVPWSQYFESMEDVEVEN-ETGKDTFRVYKSGSEG-----PVLLLLHGGGHSALSWAVFTAAIISRVQ--CRIVALDLRSHGETKVKNSED---LSAETMAKDVGNVVEAMYGDLPP-------PVMLIGHSMGG---AIAVHTAAANLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPESSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHR-----FAEPIGGFQCVFPGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVQ5-1", "uniprot_id": "PPME1_MOUSE", "id": "Q8BVQ5-1", "name": "Protein phosphatase methylesterase 1", "aln": "-MSALEKSMHLGRLPSRP----------------------PLPGSGGSQSGAKMRMGPG--------RKRDFTPVPWSQYFESMEDVEVEN-ETGKDTFRVYKSGSEG-----PVLLLLHGGGHSALSWAVFTAAIISRVQ--CRIVALDLRGHGETKVKNSED---LSAETMAKDVGNVVEAMYGDLPP-------PVMLIGHSMGG---AIAVHTAAANLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHR-----FAEPIGGFQCVFPGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y570-1", "uniprot_id": "PPME1_HUMAN", "id": "Q9Y570-1", "name": "Protein phosphatase methylesterase 1", "aln": "-MSALEKSMHLGRLPSRP----------------------PLPGSGGSQSGAKMRMGPG--------RKRDFSPVPWSQYFESMEDVEVEN-ETGKDTFRVYKSGSEG-----PVLLLLHGGGHSALSWAVFTAAIISRVQ--CRIVALDLRSHGETKVKNPED---LSAETMAKDVGNVVEAMYGDLPP-------PIMLIGHSMGG---AIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHR-----FAEPIGGFQCVFPGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38796-1", "uniprot_id": "PPME1_YEAST", "id": "P38796-1", "name": "Protein phosphatase methylesterase 1", "aln": "MSDDLRRKIALSQFERAKNVLDATFQEAYEDDENDGDALGSLPSFNGQSNRNRKYTGKTGSTTDRISSKEKSSLPTWSDFFDNKELVSLPDRDLDVNTYYTLPTSLLSNTTSIPIFIFHHGAGSSGLSFANLAKELNTKLEGRCGCFAFDARGHAETKFKKADAPICFDRDSFIKDFVSLLNYWFKSKISQEPLQKVSVILIGHSLGGSICTFAYPKLSTELQKKILGITMLDIVEEAAIMALNKVEHFLQNTPNVFESINDAVDWHVQHALSRLRSSAEIAIP-------ALFAPLKSGKVVR-----------------------------------ITNLKTFSPFWDTWFTDLSHSFVGLPVSKLLILAGNENLDKELIVGQMQGKYQLVVFQDSGHFIQEDSPIKTAITLIDFWKRNDSRNVVIKTNWGQHKTVQNT-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.:.: *.:: .**. .*... : * *.. : .**::*:. * *.: : : . :*: . :. . *:::: **.* *.**:* :: : :::: * .*:* *.*.***.*:.: :. ::: **. .::: : . . .::*****:** ::* . :::* .:**: *:*:** :*: ***.:::**:. *:.*:*:::*::* *: . * .**.::: .: :* * .:*. :* . . :** ** .**: *:. *:.***:*** :.***:* :******:*: *: :.** ::**:* *.* :: * *: : * .: * ", "identical_positions": 103, "similar_positions": 143, "identity": "23.25%" }, { "cls_id": "homologset.agr.SGD:S000001118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A520-1", "uniprot_id": "D4A520_RAT", "id": "D4A520-1", "name": "Protein phosphatase", "aln": "-------------------------------MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGG---------------------------------------SGDYGLVTAGCGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVE9-1", "uniprot_id": "PPTC7_MOUSE", "id": "Q6NVE9-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGS------------------------------------SGDYGLVTAGCGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI37-1", "uniprot_id": "PPTC7_HUMAN", "id": "Q8NI37-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGD------------------------------------------YGLVTAGCGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3N5-1", "uniprot_id": "PPTC7_DANRE", "id": "Q5U3N5-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------MLSVLSYGRLVARAVIGGLSQTDSRD-------------------------------------------------YSLVSASFGFGKD-----FRKGILKKGMCYGDDACFIARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-TNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R1-1", "uniprot_id": "Q9W3R1_DROME", "id": "Q9W3R1-1", "name": "Protein phosphatase", "aln": "MDVETSLDIEEMRRRIQQGINRCCEQLLEIAMILTHKGGQVLNRLKGASFPELAQNSENIGNGSMSENQNQRLDPMTSAQYTTLGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKD-----HIRYPEYNRGKFGEDAWFMSSSPQACIMG-VADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNR-----PEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPG-------YDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGG-KPDDITVLLASVV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0E2-1", "uniprot_id": "Q9W0E2_DROME", "id": "Q9W0E2-1", "name": "Protein phosphatase", "aln": "---------------------------MHSSLSWTSR---AISRALRSSFSTLLETATGGGSGAAAKGATK--------------SGATPGSSGAPR---------PRFVSVVCGFAKD-----NLRH-KYKPGKYGEDSWFKASTASADVMG-VADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQR-----PVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPG-------HGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGG-KPDDITVVLATVAM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAH4-1", "uniprot_id": "PTC71_DROME", "id": "Q9VAH4-1", "name": "Protein phosphatase PTC7 homolog fig", "aln": "------------------------------MITCLRNWPLLLKRFSVHQIHQFTQLSGRFERPPQSGKSSR----------------------------------DPYLVTVVQGRSKK-----PRFPGERSNQRFGEDSWFVSSTPLAEVMG-VADGVGGWRDLGVDAGRFAKELMSCCSGQTQLSDFDGRS-----PRNMLIAGFQELSHREHPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPED-------RKESYYCDKPEMAVSTRHSLLPGDLVLLATDGLFDNMPESMLLSILNGLKE-RGEHDLLVGASRVVEKARELSMNASFQSPFAIKARQHNVSYSGGGKPDDITLILSSVEVPNA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38797-1", "uniprot_id": "PP2C7_YEAST", "id": "P38797-1", "name": "Protein phosphatase 2C homolog 7, mitochondrial", "aln": "----------MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNNSHGDAYSSGSQS--------------------------------------GPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFP-SNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAA-RTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDDITVVVVRVD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. *. *:* * : ::. ******** . * *.. :: * . * :: .: .: ..: :*. ** : : : .**:*** *.* ..:: :: * **:*:**: * : * * . : *::: ****: **:. : *. : .. . *: .... * *: . .* * ****::: * ", "identical_positions": 53, "similar_positions": 67, "identity": "13.35%" }, { "cls_id": "homologset.agr.SGD:S000001119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3P4-1", "uniprot_id": "A0ABK0L3P4_RAT", "id": "A0ABK0L3P4-1", "name": "Regulator of nonsense transcripts 2", "aln": "MKIVLGHIMPAERKKSASMEEKESLLNNKEKDCSERRPVSSKEKSKDDLKITAKKEVSKVPEDKKKKLEEDKRKKEDKERKKKEEEKVKAEEELKKKEEEEKKKQEEEERKKQEEQAKRQQEE-AAAQLKEKEESLQLHQEAWERHQLRKELRSKNQNAPDNRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS----DVNCAVHLCSLFHQRY-ADFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKSIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLNFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKS-QNKDSSKDDSKEAKEPKDNKEASSPDD--LELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVRRKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKE--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSD--------DEDEGEEEEEENTDYLTDSNKENETDEENAEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGETES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AT37-1", "uniprot_id": "RENT2_MOUSE", "id": "A2AT37-1", "name": "Regulator of nonsense transcripts 2", "aln": "--------MPAERKKSASMEEKESLLNNKEKDCSERRPVSSKEKPRDDLKVTAKKEVSKVPEDKKKRLEEDKRKKEDKERKKKEEEKVKAEEELKKKEEEEKKKQEEEERKKQEEQAKRQQEE-AAAQLKEKEESLQLHQEAWERHQLRKELRSKNQNAPDNRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKLS----DVNCAAHLCSLFHQRY-SDFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKSIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKS-QNKDSNKDDSKEAKEPKDNKEASSPDD--LELELENLEINDDTLELEGADEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVRKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKE--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSE--------EEEEGEEEEEENTDYLTDSNKENETDEENAEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGETES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAU5-1", "uniprot_id": "RENT2_HUMAN", "id": "Q9HAU5-1", "name": "Regulator of nonsense transcripts 2", "aln": "--------MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS----DVNCAVHLCSLFHQRY-ADFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDD--LELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKD--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSDN-------DDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3L1-1", "uniprot_id": "Q9W3L1_DROME", "id": "Q9W3L1-1", "name": "", "aln": "--------------------------------------------MLANDSATTDSEVSTPPSSRKD-LADGVAEGDNDNDIDTGDTDANADEDVDAAAAIALEAE-------------------------EREELQQFISELREKIESKRQLR--LQNSTIELPGEEYFAKLDSNLKKNTAFVKKLKL-FTATQLDGLLREISALNLSKYISEICAALVEAKLKMT----DVPAVVTLASRLHCTY-ADFDVHFLEAWQKALNIK------ATEKIGNPSKLRVDLRLFAELVSSGVIQMKPGLAQLGVVLVHLIALDKDDHSNFSIILSFCRHCGEEYAGLVPQKMQQLATKYGVEVPKSD------FLTADKQLNLRTMLKGYFKALCKHVLAEQAELMNMTKNIRRTMECKGEISTEKREKCELMQAGFDKLLASAQSLSELLGEPLPELAKE---SEGCNPGTVIDNMLDSASFGVLD-PWGDEETRAFYTDLPDLRQFLPNFSAPKVDLETLEEPSELTEEAIDANLDAEMDLDDPPSTTSDTTPENPIEEQPTTPVAAAEDLKPQKMGNALMELGRQQQQQSQLNQNPIQIQNQMRQQFDGFLVNLFNCVNKELIDSAAIEFLLNFNTKHQRKKLTRTIFSVQRTRLDILPYLSRFVAIVHMCNTDVATDLAELLRKEFKWHIHKKNQLNIETKLKIVRFIGELVKFGLFKKFDALGCLKMLLRDFQH-HQIEMACAFVEVTGVYLYNCRDARLLMNVFLDQMLRLKTATAMDSRHAAQIESVYYLVKPPESS--KREPMVRPAMHEYIRYLIFEELCKQNVDRCIKMLRRIDWQDPETNCYAIKCLSKAYLLRFQLIRCLADLVSGLSSYQPRAVTIVIDNVFEDIRAGLEIHSPRMAQRRIAMAKYLGEMYNYKLVESTNILNTLYSIISLGVSNDQNVVSPL---DPPDSLFRLKLACMLLDTCAPYFTSQATRKKLDYFLVFFQHYYWFKKSHPVFSKTENTSDLFPILMDHTYRDCLLNVRPKLKIYKSLEQAKAAIDHLQEKLYPQLKTTNNAQDPSLGTISEISEIDEGGTDEDSGSSNDQRERQVSGQEQDQSNDWTENEAEPPLPPLPPPEKSKEDLEFEQLYEKMTTDSYQERLKEPIKATAKDIPVPMMARLQKKSYDQITGAQTIGPGINNMSQISKSVPNQDGTPGSPGADSPDGNGKSGGGVGGSDVGAAGAAGASGATSVPFVLMVRGHKGGKQQFKSFVAPSDSHLATNLKRQEQMIR-----EEKEKVKRLTLNITERIEEEDYQESLMPPQHRNFTQSYYQKPNKHKFKHQKGAPDADLIFH------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38798-1", "uniprot_id": "NMD2_YEAST", "id": "P38798-1", "name": "Nonsense-mediated mRNA decay protein 2", "aln": "--------------------------------------------------------------------------MDDGRKKELHDLNTRAWNG---------------------------------------EEVFPLKSK-----------------------------KLDSSIKRNTGFIKKLKKGFVKGSESSLLKDLSEASLEKYLSEIIVTVTECLLNVLNKNDDVIAAVEIISGLHQRFNGRFTSPLLGAFLQAFENPSVDIESERDELQRITRVKGNLRVFTELYLVGVFRTLDDIESKDAIPNFLQKKTGRKDPLLFSILREILNYKFKLG-FTTTIATAFIKKFAPLFRDDDNSWDDLIYDSKLKGALQSLFKNFIDATFARATELHKKVNKLQREHQKCQIRTGKLRDEYVEEYDKLLPIFIRFKTSAITLGEFFKLEIPELEGASNDDLKETASPMITNQILPP----NQRLWENEDTRKFYEILPDISKTVE--------------ESQSSKTEKDSNVNSKN--------------------------------------------------------------------INLFFTDLEMADCKDIIDDLSNRYWSSYLDNKATRNRILKFFMET-QDWSKLPVYSRFIATNSKYMPEIVSEFINYLDNGFRSQLHSN-----KINVKNIIFFSEMIKFQLIPSFMIFHKIRTLIMYMQVPNNVEILTVLLEHSGKFLLNKPEYKELMEKMVQLIKDKKNDRQLNMNMKSALENIITLLYPPSVKSLNVTVKTITPEQQFYRILIRSELSSLDFKHIVKLVRKAHWDDVAIQKVLFSLFSKPHKISYQNIPLLTKVLGGLYSYRRDFVIRCIDQVLENIERGLEINDYGQNMHRISNVRYLTEIFNFEMIKSDVLLDTIYHIIRFGHINNQPNPFYLNYSDPPDNYFRIQLVTTILLNINR--TPAAFTKKCKLLLRFFEYYTFIKEQPLPKETEFRVSSTFKKYENIFGNTKFERSENLVESASRLESLLKSLNAIKSKDDRVKGSSASIHN-GKESAVPIESITEDDEDEDDENDDGVDLLG-EDEDAEISTPNTESAPG-----KHQAKQDESEDEDDEDDDEDDDDDDDDDDDDGEEGDEDDDEDDDDEDDDDEEEEDSDSDLEYGGDLDADRDIEMKRMYEEYERKLKDEEERKAEEELERQFQKMMQ--------------ESIDARKSEKVVASKIPVISKPVSVQKPLLLKKSEEPSSSKETYEELSKPKKIAFTFLTKSGKKTQSRILQLPTDVKFVSDVLEEEEKLKTERNK---IKKIVLKRSFD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . : ...* : ** : .: :***.:*:**.*:**** :. . ..* :::. .*.**::* .::.*. *:: ** ... : * :* : . * :* .: : :: :: . :::: :**.::** *:: .: : ... . :: : . . :.. *: . .: : .. : ::.::* :: : : : :: : :: :: .*:: : :: : : : :: :.: :*.::: :*:* .. * . . * :*::* ** * *: : .: : ::. : .: *: :* . :::**. : : . : :: :* . ** :*::* .::. :: . * *: :::.: : : * : *:.*: ** :: . : :: *: :. :::*: .::* * :* . : : . ::: : * :: . : :*. ** . : .. ::: * *: .:*.. .: :: :*: *:* : : : : : :: * ::.::.** *: :* *:*:*. *:*::. :**: .::* *::*:.:::* :: *:* : :* : * ***: **::*. :* . : :* . :* :*: * : *:. . * : : . :: . **. :: :: : . . . : ..: *. :*:. . ..:: : . *. . ... .: * :: :. :: .: : .. :.:. : . :: . . : .. : : * .:: : * . : . ..:: ** : *:::: : : :: .. * . . :. .: : :: * .:::: ", "identical_positions": 123, "similar_positions": 385, "identity": "9.1%" }, { "cls_id": "homologset.agr.SGD:S000001120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BS95-1", "uniprot_id": "GPHR_MOUSE", "id": "Q8BS95-1", "name": "Golgi pH regulator", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKLNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVARRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LTD0-1", "uniprot_id": "F1LTD0_RAT", "id": "F1LTD0-1", "name": "", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVTRRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7ZAQ6-1", "uniprot_id": "GPHRA_HUMAN", "id": "B7ZAQ6-1", "name": "Golgi pH regulator A", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIR--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAMARRTMFQK---GEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG08-1", "uniprot_id": "GPHRB_HUMAN", "id": "P0CG08-1", "name": "Golgi pH regulator B", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIR--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAMARRTMFQK---GEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB29-1", "uniprot_id": "E7FB29_DANRE", "id": "E7FB29-1", "name": "", "aln": "MSFFVDSVIMFTS---------QVLFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVVFSITFAFSCTMFELIIFEILGALSSS--------SRYFHWKLNLYVILLVLIFVVPFYIGYFVVSNIR--LLQRQRLLFSCVVWFTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDSDILALERR-----------LLQTMDMIVSKKKR---IAMTRRQMYQR---GEEQNKQTGFWGMIKSVTSSPSGSENLSLIQQEVDALEELSRQLFLETVDLQATKERIEYSKTFQGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLVLAQIMGMYFVSSVLLMRMSMPLEYRSIVSEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38799-1", "uniprot_id": "YHN8_YEAST", "id": "P38799-1", "name": "Uncharacterized protein YHR078W", "aln": "MEALIVFIVLSVSGAFAYKCSYERLWFKVGSLFDIISTSSKKNVIPLASKMEVGSNEDVSSMGNFINKFYTEYSLPSHKVLQSLRVLFSLAMMTYTVTIEIILWQIKVAGMDKEVTFITTWVWPLTAIMLSFILILFQPFFIIISLLNKFYNDKFDIDRLIIVTCIILSTLIALLSYINIGPFQYTKN-------ILTRLSIGGVTVMASLSGLATVSSLYYNFLVIWHKFRNTPMSDPSFRNINNSNNNSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSLEEEVGENSTFKAELMEKIAWYQLELGKLEALLQQSPQVRTFKKAFEVGFIIYCLHKLIITFLKRIPYIIYHSLKYPDDYDYENFSENAASDPLAITIANILDFSFFRFNYQHDLDSLTKQISLFLSISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTNNSSYKGKKRNYSQEQKGISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLGGKFTVPNIVIDSWFDEVYAFACVFTFICIRIAERKLSTKKVSVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: :: .* : *:* .* ** *:.:::.:*.: .: * : : *::: : : * ** :. : : * :. :: ::*::. **:* ::.:: :. :**:: : :: : : . : *: .*: :::*:.: ***:** ***:.:*.. * : : ::. :: : . * ** * * :.:* : : :. : : :: : :::.:: :* : *: :. :.: : : * * : * : :: * * ** .. . : ** ::* :.:: .: :.: :.:.:: :* : . * *.:: : : : :* ....: * : *::::: *:*.:::.*::* :* * :.*:** : . . *** :: .:.: ::: : :*.:: . *::: ", "identical_positions": 72, "similar_positions": 189, "identity": "12.88%" }, { "cls_id": "homologset.agr.SGD:S000001121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTI7-1", "uniprot_id": "D3ZTI7_RAT", "id": "D3ZTI7-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MARPVQSFQLWSALGFLLQLA-IFLGKLGPQVQSVRP-------------------------------------------------------------------------------ESLLFVSTLDGSLHALNKQTGDLKWTVKDDP-----IIQGPMYVTEMAFLSDPADGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQ--------------MTLTTE-----GFSTP--QLYIGRTQYTVSMHDPRTP---TLRWNTTYRRY-SAPPVDGS-PGKYMSHLTSCGMGLLLTVDPGSGTVLWTQDLGVPVTGIYTWHQDGLRQLPHLTLAR--DTLHFLVLRWGHIRLPASSSQDTVTQFS-SLDTELLMTLYVGKEEAGFYVSKALVHAGVALVPRGLTLAPMDGPTTDEVTVQV-SGEREGSPSTAVRYPSGSVALP------SQWLLIGYHEPPPVLHTTMLRVQRTPGKGSADTRDSDDLHAP--ALSFEFLNLKREEPWDPELHPEEKA-DTYPGLG-------SQDLLAASFTAILLGAWVLYLMR-----QQQ--------QSPSAPAGPSDLPQ------------------DTQVQLSRDT---------LQNQRRFQSPPEPVQPAHDP--------EAEQPTVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFSLVQREVQLLQESDRHPNVLRYFCTEQGPQFHYIALELCQASLQEYVESPDLD----RWG--LGPTMVLQQMMSGLAHLHSLHIVHRDLKPGNILMAGPD--------SQGQGRVVISDFGLCKKLPAGRCSFSLHSGIP-GTEGWMAPELLQ-----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGESLYRQANILSGDHCLAQLQEETHDK----VVALDLVKAMLSLLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPEQGP--LVTALEAGSYKVVR-ENWYKHISAPLQEDLKRFRSYKGTSVRDLLRAMRNKKHHYRELPTEVRQTLGQLPAGFAQYFTQRFPRLLLHTHRAMRTCASESLFLPYYPA----------------------ALEARGSCQVPQRAETPRGPKGRPRS-----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E3-1", "uniprot_id": "ERN2_MOUSE", "id": "Q9Z2E3-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MARPVQRFQLWSPLGFLLQLV-TLLGKLGPQVQSVRP-------------------------------------------------------------------------------ESLLFVSTLDGSLHALNKQTGDLKWTVKDDP-----IIQGPMYVTEMAFLSDPADGSLYVLGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQ--------------MTLTTE-----GLSTP--QLFIGRTQYTVSMHDLRTP---ALRWNTTYRRY-SAPLLNGS-PGKYMSHLTSCGMGLLLTVDPGSGIVLWTQDLGVPVTGIYTWHQDGLHQLPHLTLAR--DTLHFLVLRWGHIRLPASSYQDTATQFS-SLDTQLLMTLYVGKEEAGFYVSKALVHAGVALVPRGLTLAPMDGPTTDEVTLQV-SGEREGSPSTAVRYPSGSVALP------SQWLLIGYHEPPPVLHTTMLRVHPIPGKVSAETRASEDLHAP--PVFFELLNLRRE---DPELHPEEKASDSYPGLG-------SQDLLAATFTAILLGAWVLYLMR-----QQQ--------QSPSAPAGPPDLSQ------------------DAQGQLSRDI---------LQDQRRFQSPSEPAQPPHDP--------EAGQPTVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTEHGPQFHYIALELCQASLQEYVESPDLD----RWG--LEPTTVLQQMMSGLAHLHSLHIVHRDLKPANILMAGPD--------SQGQGRVVISDFGLCKKLPVGRCSFSLHSGIP-GTEGWMAPELLQ-----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGESLYRQANILSGDPCLAQLQEETHDK----VVALDLVRAMLSLLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPDQGP--LVSALEAGSYKVVR-EDWHKHISAPLQADLKRFRSYKGTSVRDLLRAMRNKKHHYRELPAEVRQTLGQLPAGFIQYFTQRFPRLLLHTHRAMRTCASESLFLPYYPP----------------------ALEAR-------RPDATKS------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q76MJ5-1", "uniprot_id": "ERN2_HUMAN", "id": "Q76MJ5-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MASAVRGSRPWPRLGLQLQFAALLLGTLSPQVHTLRP-------------------------------------------------------------------------------ENLLLVSTLDGSLHALSKQTGDLKWTLRDDP-----VIEGPMYVTEMAFLSDPADGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQ--------------MTLTTE-----GPSTP--RLYIGRTQYTVTMHDPRAP---ALRWNTTYRRY-SAPPMDGS-PGKYMSHLASCGMGLLLTVDPGSGTVLWTQDLGVPVMGVYTWHQDGLRQLPHLTLAR--DTLHFLALRWGHIRLPASGPRDTATLFS-TLDTQLLMTLYVGKDETGFYVSKALVHTGVALVPRGLTLAPADGPTTDEVTLQV-SGEREGSPSTAVRYPSGSVALP------SQWLLIGHHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAP--AFFLELLSLSREKLWDSELHPEEKTPDSYLGLG-------PQDLLAASLTAVLLGGWILFVMR-----QQQPQVVEKQQETPLAPADFAHISQ------------------DAQSLHSGAS---------RRSQKRLQSPSKQAQPLDDP--------EAEQLTVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQEYVENPDLD----RGG--LEPEVVLQQLMSGLAHLHSLHIVHRDLKPGNILITGPD--------SQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIP-GTEGWMAPELLQL----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDK----VVARDLVGAMLSPLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEP--LVRALEAGGCAVVR-DNWHEHISMPLQTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALGQVPDGFVQYFTNRFPRLLLHTHRAMRSCASESLFLPYYPP----------------------DSEAR-------RPCPGATGR----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQY0-1", "uniprot_id": "ERN1_MOUSE", "id": "Q9EQY0-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "---------MPARWLLLLLALLLPPPGPGSFGRTSTVTLP-------------------------------------------------------------------------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTR---ELRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQGEVLRKVVHINVAV--ETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDNTPTTVSQDVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSVHQQRQLQHQQFQKELEKIQLLQQQQ--LPFHPHGDLTQDPEFLDSSGPFSESSGTSSPSPSPRASNHSLHPSSSASRAGTSPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA----HLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSE----------------------------DCKDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACNLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGP--IVRQLERGGRAVVK-MDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQTYYWH----------------------EPTEP------QPPVIPYAL-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2H4-1", "uniprot_id": "A0A0G2K2H4_RAT", "id": "A0A0G2K2H4-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "---------MPARWLLLLLALLLLPPGPGSFGRASTVTLP-------------------------------------------------------------------------------EALLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTR---ELRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAV--ETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQ--LPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA----HLG--LEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPN--------AHGRIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSE----------------------------DCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHED----VIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGP--IVRQLERGGRAVVK-MDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWH----------------------EPTEA------QPPGIPDAL-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75460-1", "uniprot_id": "ERN1_HUMAN", "id": "O75460-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "---------MPARRLLLLLTLLL--PGLGIFGSTSTVTLP-------------------------------------------------------------------------------ETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP-----VLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSS-------------DGILYMGKKQDIWYVIDLLTGEKQ--------------QTLSSAFADSLCPSTS--LLYLGRTEYTITMYDTKTR---ELRWNATYFDY-AASLPEDD-VDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAV--ETLRYLTFMSGEVG-RITKWKYPFPKET-EAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGD-KGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA----HLG--LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPN--------AHGKIKAMISDFGLCKKLAVGRHSFSRRSGVP-GTEGWIAPEMLSE----------------------------DCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHED----VIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGP--IVKQLERGGRAVVK-MDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH----------------------EPPEP------QPPVTPDAL-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQI8-1", "uniprot_id": "A0A8M1QQI8_DANRE", "id": "A0A8M1QQI8-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "------MMRMMKNWTQMLLLLVCFAGIVSQCEGGSSVSLP-------------------------------------------------------------------------------ESLLFVSTLDGSLHAVSKQTGDIKWTLKEDP-----IIQVPEYFQEPGFLPDPNDGSLYVLGGKRKEGLMKLPFTIQELVQSSPCRSS-------------DGVLYTGKKQDTWFVVDPQTGEKQ--------------TSLSTSSSDSICPSAP--LLYIGRTEYMITMYDTKTQ---ELRWNATYNDY-SAPLYDDKKYEYKMSHFASSGDGLVVTVDRDSGEVLWMQKFDSPVAGFYLWSQDSLRRAPHLTVAT--ETLRYLTFTAENTQSHTMKWTYQFTKESHSTKTQLVPTLYVGKTESHLYASASLVHQGVAIVPKGLTLARIEGPMTAGVTMGNGRPECEITPSTDVKYPPGSSSS-----LQNQWLLIGHHEIPPLAHTTMLRDFPENLQRSGDVIPPRGS-------------GSSYRSPSHPLPPVR-KQSSSPVLP----DSLSSEPMTVLVVTLLLGAWITFLLTHKWPVKKS-----QRSEEPVDSTPLSGLTN----YSASTELNTPP----STSSYSNSS--RSEKTSSVASNQTQPFSSKDSAPVTAASQSQN---EQADVVEVGKISFSPAEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFCTERDRQFTYIAIELCAATLQQYVEDPSCP----HSE--LNPVSLLEQTMCGLSHLHSLNIVHRDLKPRNILLSLPG--------ALGRVRALISDFGLCKKLPDGRHSFSLRSGIP-GTEGWIAPELLIN----------------------------APKGNPTSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHED----VIGRDLIERMISAEPESRPSAASILKHPFFWSPEKQLQFFQDVSDRIEKEPTESP--IVARLENSGRSVVR-TNWRMHISAPLQADLRKFRTYKGNSVRDLLRAMRNKKHHYHELPPEVQSALGEVPDGFVAYFTSRFPRLLLHTHTALSICAPERPFHPYYHH-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR46-1", "uniprot_id": "A8JR46_DROME", "id": "A8JR46-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MRFCVVVCCVLFLLASGLIASATAKSQQGDSAEVVSSGEDEKTDCTDLA----------------------------------------------------------------RDEEALMVFSTLGGGLTAIDPVTSEIRWTIADDPPI---VAEHQENVQVPHFLPDPRDGSIYQLG--QMGSLKKLPYTIPQLVANAPCRSS-------------DGILYSGKKSDTWYMVDPKTGRREKVMG-------FGDATVDGKEGEQIGWATSR-AIYLGRTQYTVMMYDSLAKNKDAKPWNITFYDYNAVSAPPELAKEYEYIHLTTTTNGQIVTLDRKHGKFLWQRDLSSPVVAAFLLGPDGLLSVPFTTVSD--EAYQAILEES---------------KTGNVNTVKLFQSLYVGEHQKGLYALPSLVDKNTPRISTAPPIKLLDGPTGDQNSNQE-TDPRTIYINDVLQEHAG--------------IMLGHYNMPNEGNGNLQLSPTTASSKVVQSLATIHNYNDGYGLLANNEKNAADIGVQTDPELVEIGIDQRTNGN---------TINRTKTIILQNSNKVQAFINEWFMEHPSGKVHQILIVIVLGMIALFWYTCS------------------TMRELQKQSENGSKTFAIAQNGSNGSTGSNGSNANAEDLVD-----LGNGQVRVGKISFSTNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVALLRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYTEGDRSL----ELQNHIDVWQVLSQAASGLSHLHSLDIVHRDIKPQNVLISLPD--------AKGKVRVMISDFGLCKKLNFGKTSFSRRSGVT-GTDGWIAPEMMR-------------------------------SQRTTTAVDIFSLGCVYYYVLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQLISDMIHKDPQSRPPARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAE--PLKSLEKNGRIVVL-DDWNVHLDPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPHEFTNYWVDRFPQLISHAYHAFSICSNEPIFKPYYSAGYLFTRPWYFDADDALFPMLMLDPKPLPKIGSPKKTPSPASSQAQQLKQRKGLYNFRKPNDELPIPGVGLQRNLELDGQSLEPDGKRDVFANFKFRRYSKPGNNRNYNGGHKEAQDKEKYVIWTLPPSTQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32361-1", "uniprot_id": "IRE1_YEAST", "id": "P32361-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGAS-YNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENY---EKTNSLDTTHKYPPLMIDSS------VDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQR---FKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGKQVVFEGAVN-------------DGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIAN-----IPNFEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRS--LIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . ::. : : *.* *:. .. : *:: : : . * *. .* *** :* :** :* : . * .* * : :: .*. :: : :*:* : : ::. :. .. :.. ::: * * : : * :. :. : : . : ::.. . : . . : . : : : . . . : . . : . . . * . . .:** * **.*::* *: * *****:* : :. *: ** *** * **:**:*:* :* ***:*** .**: .* . :* * .*::*****.*:***:** *:*:: .. . : ::********* *: ** . . . **.** ***:: * ::**** ***:**: * * *.**.. *::**: * : . . . :*: *: * **.* : **:** * *.*: .*** :* . : :: .. *: :* :: : :*.::* * . .: *****:*** **: :*. . :* :* * *:..***.*: .: . : : : ", "identical_positions": 157, "similar_positions": 191, "identity": "12.28%" }, { "cls_id": "homologset.agr.SGD:S000001122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEF1-1", "uniprot_id": "ASTRA_MOUSE", "id": "Q8VEF1-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR----------------------------------------------------------LQLLPPIRPPPASEPEPG-------TMVEKGSDSSS----------------------------------EKSG----------VSGTLSTQSLGSRNFIRNSKKMQSWYSMLCPTYK--QRNEDFRKLFSK--LPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPR----------------ELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLGSP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ISPSGAADHSQEPSPVGSRRGRVTPNLSRASSDADHGAEE-DKEEQTDG-LDASSSQTVTPVAEPLSSEPT------------------------------------------PPDGPTSS--LGPLDLLSREELLTDTSNSSSSTGEEG---DLAALLPDLSGRLLINSVFHMGAERLQQMLFSD-SPFLQGFLQQ-RKFTDVTLSPWSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLDRELAKAEKLSLEEG---------------------------GKDTRGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALNALLFYRLWSLER--------------------TAHTFESWHSLALAKGKFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVPDPPLDTQPQPDDSFP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR56-1", "uniprot_id": "ASTRA_RAT", "id": "Q3KR56-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR----------------------------------------------------------LQLLPPSRPPSAPEPEPG-------TMVEKGSDSSS----------------------------------EKSG----------VSGTLSTQSLGSRNFIRNSKKMQSWYSMLCPTYK--QRNEDFRKLFSK--LPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPR----------------ELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLGSP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ISPSGAADRSQEPSPVGSRCGRVTPNLSRASSDADHGAEE-DKEDQTDSQLDASSSQTVTPVAEPLSAEPA------------------------------------------PPDGPTSN--LGPLDLLSREELLTDTSNSSSSTGEEG---DLAALLPDLSGRLLINSVFHVGAERLQQMLFSD-SPFLQGFLQQ-RKFTDVTLSPWSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDRELAKAEKVSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALNALLFYRLWSLER--------------------TAHTFESWHSLALAKGKFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVPDPPLDTQPHPDDSFP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CP6-1", "uniprot_id": "ASTRA_HUMAN", "id": "Q96CP6-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSTPSSSPSLRKR----------------------------------------------------------LQLLPPSRPP--PEPEPG-------TMVEKGSDSSS----------------------------------EKGG----------VPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK--QRNEDFRKLFSK--LPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPR----------------ELWHLVHQCYGSELGLTSEDEDYVSP--LQLNGLGTP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEE-DKEEQVDSQPDASSSQTVTPVAEPPSTEPT------------------------------------------QPDGPTT---LGPLDLLPSEELLTDTSNSSSSTGEEA---DLAALLPDLSGRLLINSVFHVGAERLQQMLFSD-SPFLQGFLQQ-CKFTDVTLSPWSGDSKCHQR-RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRA-HGD------GPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIVICVSLIILIALNVLLFYRLWSLER--------------------TAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPDDSFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NZU2-1", "uniprot_id": "A0A8M9NZU2_DANRE", "id": "A0A8M9NZU2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYEGLLVMAMTTPPEILIAEPISIPILNILPPSSDTESWSRSPSPRAHRYRSRSREKRKAKAQQEDKSGAKHCDKRKGELERSPSHASASSSMVCNVDDEEQGNPCVLLLPPSRSWSRSSSLSRRSRWSIRSLLNKDSDCDSSSTASNSPRSTPGSSPSLRRRVLGGRASEGETAGEKSGGGSDSPLPPTPSSSTSSYPLAARHFTRNAKKMQSWYNVLSPTYK--QRNEDFRKLFKK--LPDTERLIVDYSCALQKDILLQGRLYLSENWLCFYSNIFRWETTITILLKDVTNLTKEKTAKLIPNAIQISTENEKHFFTSFGARDRSYMMIFRLWQNALMDKTLSPK----------------ELWHIVHQCYGTELGLTSEDDDYVSPTAEHMNGLLPG-EEPVSVTDLLD------------------------------------------------------------------------------------------------------LGSVPVAPASSSPPSSASVLPCASGSSPPSSSSSSQPVEVPSIRASIDPEPSPPSSQSSLPPVTNTGAVPASVILK---------------------EGGDSQSESANHSLQSPPSIPHNLGNLSSLDMTNDEDLPTDPSNSSD-TQEES---EVESFCADLNGRLHINTVVRMGVDKLHDLLFSD-THFIQHLFSQ-RHFTDLSVHEWQQDSSSGSSSRVLSYTIAINNPLGPKTAPVVETQTLHKSSSRSECYVVDSEVITSGIPYQDYFYTVHRYCLTSVNKHKSRLRVSSDICYRKQPWSLVKALIEKNTWSGIEEYYRHLEMEVCKLETLLQTEVT------------------VVSAGEMPSPDSTKTPPGLRRRKRTCPRRAGERDRDREAAGGGERGDRITDERDRREAGGQYMKLGERWRAGGGSNNNSISTILLI----------------------------------------------------------------------------------------------------------VSFI----LVVLVALNMMLFYKLWALER--------------------AAHTLETWHSYSLTDSPLPQSAGEWAQVLQLQRQFHQAQMNKWQQILQSSVTLLDQMKQSLEKLHRGMIPPEGQQESDPEPDTLADQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CI52-1", "uniprot_id": "ASTRC_MOUSE", "id": "Q8CI52-1", "name": "Protein Aster-C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGALTARQI--------------------------------------------------------------VNEGDSSLATELQ---------EEPEESPG------------------------------------------------PVVDENIVSAKKQGQSTHNWSG--DWSFWISSSTYK--DRNEEYRQQFTH--LPDSEKLIADYACALQKDILVQGRLYLSEKWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLIIFRLWQNVLLDKSLTRQ----------------EFWQLLQQNYGTELGLNAEEMEHL-LSVEENVQPRSPGRSSVDDAGERD------------------------------------------------------------------------------------------------------EKFSKAVSFTQESVSRASETEPLDGNSPKRGL-------GKEDSQSERNVRKSPSLASEK----RISRAPS-----------------------------------------------------KSLDLNKNEYLSLD--KSSTSDSVD----EENIPEKDLQGRLYINRVFHISAERMFELLFTS-SHFMQRFANS-RNIIDVVSTPWTVESGGNQL-RTMTYTIVLSNPLTGKYTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLESYFKKLESDLLMEESVLSQSI-----------------------------EDAGKHSSLRRRRRTLNRTA-------------EPVPKLSSQRSSTDLGFEAKVDVT--GKRKTVDSYDTALIVV-----------------------------------------------------------------------------------------------------------MSIFL----LLLVLLNVTLFLKLSKIEH--------------------ATQSFYQ---LHLQGEKSLNLVSDRFSRTENIQK-NKDQAHRLKGVLQDSIVMLEQLKSSLIMLQKTFDLLNKNKSGVAVES-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A135-1", "uniprot_id": "D4A135_RAT", "id": "D4A135-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTQAVLWRSPSREEP--------------------STPQTNSQCQADSPI--------------------------------------------------------------VNDGDSSLATELQ---------GELEENSS------------------------------------------------PAVDESIVSAKKQGPSTHNWSG--DWSFWISSSTYK--DRNEEYRQQFTH--LPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQ----------------EFWQLLQQNYGTELGLNAEEMEHLSLSIEENVQPRSPGRSSVDDSGERD------------------------------------------------------------------------------------------------------EKFSKAISLTHESVSRASETESLDGNSPERGL-------GKEGSQSERHVRKSPSLASEK----KLGRVPS-----------------------------------------------------KTLDLNKNEYLSLD--KSSTSDSVD----EENIPEKDLQGRLYINRVFHISAERMFELLFTS-SHFMQRFTNS-RNIIDVVSTPWTVESGGDQL-RTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLENYFKQLESDLLMEESVLSQPM-----------------------------EDAGKLSSLRRRRRTLNRTA-------------EPVPKLPSQRSPTDLGFEAKDDIT--GKRKAVDSCDTALIVV-----------------------------------------------------------------------------------------------------------MSVFL----LLLVLLNVTLFLKLSKIEH--------------------ATQSFYQ---LHLQGEKSLNLVSDRLSRTENIQK-NKDQAHRLKGVLQDSIVMLEQLKSSLIMLQKTFDLLNKNKSGVVVES-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYS0-1", "uniprot_id": "ASTRC_HUMAN", "id": "Q8IYS0-1", "name": "Protein Aster-C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGAPTVRQV--------------------------------------------------------------MNEGDSSLATDLQ---------EDVEENPS------------------------------------------------PTVEENNVVVKKQGPNLHNWSG--DWSFWISSSTYK--DRNEEYRRQFTH--LPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQ----------------EFWQLLQQNYGTELGLNAEEMENLSLSIED-VQPRSPGRSSLDDSGERD------------------------------------------------------------------------------------------------------EKLSKSISFTSESISRVSETESFDGNSSKGGL-------GKEESQNEKQTKKSLLPTLEK----KLTRVPS-----------------------------------------------------KSLDLNKNEYLSLD--KSSTSDSVD----EENVPEKDLHGRLFINRIFHISADRMFELLFTS-SRFMQKFASS-RNIIDVVSTPWTAELGGDQL-RTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAI-----------------------------EDPGKLTGLRRRRRTFNRTA-------------ETVPKLSSQHSSGDVGLGAKGDIT--GKKKEMENYNVTLIVV-----------------------------------------------------------------------------------------------------------MSIFV----LLLVLLNVTLFLKLSKIEH--------------------AAQSFYR---LRLQEEKSLNLASDMVSRAETIQK-NKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAVES-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q853-1", "uniprot_id": "A0A8M9Q853_DANRE", "id": "A0A8M9Q853-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTETP--------------------KPLMGNELAQENGQS--------------------------------------------------------------GEVRGSSEEQEMKGI------TQTPKQPMG------------------------------------------------KATDGKNPEEQEALEVTVQFTAAPQSTDSLYYTSYK--QRSDEFRKLFKE--VPEHEKLVVDYTCALQKDILLQGRIYFTENCLCFYSHVFR-GTKIMVNMKDIISVSKEKTAKWIPNAIQISTNSEKLFFSSFSTREKSYQSIFRLWQNVLMEKKLTKL----------------ELLQMVRQHYGNDLGLSHDEMESFQTSVDTITPTLPSLNMRGEDYTGRP------------------------------------------------------------------------------------------------------ERPTSLRLPHGELNSYEASTPQGDDTQSSVGLHSVLSANGGDDSLSTPSHQLSPNLSLNRSGSERVSKRSS-----------------------------------------------------FSLDLNANEDQLSDNSRSDSLEEVE----ERETASPVSQGRLFVNRVFHISAEKMFNLLFSD-SSFTRRFMDI-RKITGITATPWKKEASGCMK-RTLNYTITINNPLVGKFSTATETQTLYKESREGQYYMIDSEVYTHDVPYHDYFYTQNRYCIIRNSKHKCRLRIYTDVKYKKQPWGLVKSFITKNSWSGLEDYFRHLEAELLDEEAELTQGS-----------------------------GDAGKTGALRRRRRTYSRTL-------------QEHMKPAKAQYSTDSEQQRTGTMGPMDIKNTPHRWNITSVVFG----------------------------------------------------------------------------------------------------------MSLIL----FVLVVLNLGLFFKLWAMED--------------------VAHRMYLNTKHRMKERVESSLPPDLGPRHGMPHR-SQEEVHLLRAVLQDSINLLEQLRSSLLVLQQNFQVYNRTSSPL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "R9PY62-1", "uniprot_id": "R9PY62_DROME", "id": "R9PY62-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKEDIKKPPRKTLNVDAKKAKRKKMIKDSDKINPTTSSVNITVTTAESSSSCKNPANANMIPETTQPDQLQSQTQTQAQLQPQSQSPSQCQQAQENPEHLQQQSQPEEELQAEAPGSNAGDRRDSITEEITITSTTNSSQSTKLLTIQEAAGSFEQSSVSAVSTSSKQIASTTAGGSPPAAAAPGANEFNGSVLRLTQAATSTSPGSISSAGNTATLGAAPSINIVSSESTRDQTQQPQSVDPNGVAAPGDSPSSRKSSTSSKGKASQAKLSTSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTSNEKPAKTSRLSERAKKKSWYNVIYPNYK--SRAEDFKKLFKD--VPNDERLIVDYSCALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSGKDKYFFATFTSRDKSFLMLFRVWQNTLMNKQFSPQ----------------EIWQHVHTCYGDELGLTTDDEDYIDPTLNKTNEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSGGGVRASAPRKSKTKYFFNSSKSSANASASGSDNNKTRESSRKLNKKMKQNAKELTLSSVKPTELSVSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSGSLSGSNTAAASGSGSDKMSAEKKVSTASNSAAVAAAEAAQSLASAS-----------------------------SGSGSLESKMEMKRKLGKMHRQREEGKNAAESVPTDVSDSSDSEENNLPFVPTTECTSTHEGRQIVHTILPINVDTLFNLLFSK-SKFITDFHAM-RKSTDLVLGEWTKNEEGLQV-RTVNVTVQLAASVGPKTSKVTEYQTQRECSKPGELYSIDVNSVNAGIPYAESFSVLIHFCLARTVDDHTMLSIHTQIKYKKSIWGVVKGFIEKNTWAGLEDFFGAQLHALQSETCIPPAKGKGRRPRRGMNQQSATSTSTTSITTGALHTATSTDNDSIQESRHPHQQDQHQHQHLHMHHHHHHHHGSQHHHHDARHSHHHHHQPLLPHHQQQHPHHWHHRKALLQSGRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVGAAAGHPLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGDGQPLASGQGSQGHRLRHKGLWLLVILLLCLMLALNVILLLKLWRLEER-----------------IDVDLNRRARMPSLAALSELPSTNQEWLELLRDQEMAHENELHKWQQVLQTAIELLKKVSIVCEKITNDSHLRQSIESMSMAGRTEF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38800-1", "uniprot_id": "LAM4_YEAST", "id": "P38800-1", "name": "Membrane-anchored lipid-binding protein LAM4", "aln": "MTRDSKKKHHWGTAFLRTIGVKRKHKKDRNFLNNTTGENVSTTASAERFRRVGGNPDIPSLLKPETFTESPAKGSQKAAASSLAHSQGVFNIPIVIDPMETNRLEKTNTNLTAGSLKGRFQDGNSNSNSVPSLSVQALEKEKLQSGKREGSSNQAEEKTPDGHDEHTAFETFLSFAHNAVSHIPKINVQDADNGTISRNEPKDRKKNSSNISGALSENSTNNKNTSSTKESDGPFLKNLDNILAASKSSTPSNQQLNTTEAGSKSKPSSLSRLAFGNLKGHIHSNSHSSSNAISGDDTSLDDTRKMTDDMARKVVFEPIRHSHDKPTPGVGNLKLEHFDDSQATLEGLEAMSAESLPEADHLDSRGPVQQSNLERKTVPSKWSVVSSSTTDGVKPRRRAKSMISAMADKQNTSSDVLQDCKKRLSFNSSNGLTNNDPEYEDREPREMSKKFLNRRSFSPGSISMGMKVLPSTALKYSLNKVKNSTDIASTIIPRPSMSNGRPSSGLRRSSSKSFSSTPVNIIEPSEENGRQSSIRIKGVEYASEKKDAEFHAIFKDSGVSPNERLILDHSCALSRDILLQGRMYISDQHIGFYSNILGWVSTVFIPFKTIVQIEKRATAGIFPNGIVIDTLHTKYTFASFTSRDATYDLITEVWNQIILGKRFRSNSNNTNSSSNSISDDENDDYDDDYDDYGDDDDDLYDNSNNISDSTDMTSSVSIGKPEDLPMPLQTDTPYG----------------------------TGIPPLGPKIHSPTETVYKPAPNEKLVNESTIHASLGRVVNILFGKDVSYIMAILKAQKNSDISPIPVLVDSPTVSEGKKRDYSYVKTTPGAIGPGKTKCMITETIQHFNLEEYVQVLQTTKTPDVPSGNSFYVRTVYLLSWANNNETKLKLYVSVEWTGKSLIKSPIEKGTFDGVTDATKILVEELGNILTRSATKRKRSSKENTVTVSTLPKMEPSSHAPTEPDIQKDKDDSIIRENENIPAPLGTVVQLLFGSNTEYMQKVITRDKNNVNVETIPKFTPSLVEGGSRHYEYTKKLNNSIGPKQTKCLLTESIEHMDIN-NYVLVTQTTKTPDVPSGSNFAVESKIFLFWGQHDTTNMTVITKINWTSK--SFLKGAIEKGSVEGQKVSVDYMLSELRDIISRAKSKK------------------------------PVKKVMKSHDKHRPFHSKVEQKS-------SESRKSDDNKDILTHILDFVQNNFSSEIFMNKLLSPQKLFLILGLT---------------------------------------------------------------------------------------------------------IMLFWSPRLHVFQEKNNLQIIKPGRLLIDGQEYNYVPSFGTLYNSYENAISSKKKRENVNYARDKSPIVGRESDIWDWISNRGSAISPRGRAMLRNDDEHKLQQLSESIKITEMQLNHMKTMLDNIERDANDLS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * .: ::: *.. :. *:*: *::***.::**:***:*.::: : *::::: : : : * : : *. ** :**.* * : * *::* :*: : : .:*:: :: * : : . ** : . :: : . . . . . . : : . . : . : ::** . : : . : .: * * : : * : :: . . : . .:* . * . : : . : : :.: : .. ..:*. * *.: . : : : ::. : : .. :: * : : : . : . . . : . *.:: . ", "identical_positions": 43, "similar_positions": 140, "identity": "2.83%" }, { "cls_id": "homologset.agr.SGD:S000001123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQL4-1", "uniprot_id": "A0ABK0LQL4_RAT", "id": "A0ABK0LQL4-1", "name": "Nuclear nucleic acid-binding protein C1D", "aln": "MRLILERLELRDDWRRGEPRNAIARVRTRKTGNDACAGGKKTVSWRHHCATSFPETGVHGIELVTMAGEEMNEDYPVEIHDSLTALESSLGAVDDMLKTMMS-----VSRNELLQKLDPLEQAK----VDLVS--AYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKK----AAKLDRGAASRFVKNALWEPKPKN-TPKVANKGKSKH---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35473-1", "uniprot_id": "C1D_MOUSE", "id": "O35473-1", "name": "Nuclear nucleic acid-binding protein C1D", "aln": "-----------------------------------------------------------------MAGEEMNEDYPVEIHESLTALESSLGAVDDMLKTMMA-----VSRNELLQKLDPLEQAK----VDLVS--AYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKK----AAKLDRGAASRFVKNALWEPKAKS-TPKVANKGKSKH---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13901-1", "uniprot_id": "C1D_HUMAN", "id": "Q13901-1", "name": "Nuclear nucleic acid-binding protein C1D", "aln": "-----------------------------------------------------------------MAGEEINEDYPVEIHEYLSAFENSIGAVDEMLKTMMS-----VSRNELLQKLDPLEQAK----VDLVS--AYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKK----AGKLDRGAASRFVKNALWEPKSKN-ASKVANKGKSKS---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ97-1", "uniprot_id": "C1D_DANRE", "id": "Q5XJ97-1", "name": "Nuclear nucleic acid-binding protein C1D", "aln": "-----------------------------------------------------------------MADDAAVEDYPTEIEDNLNDFDSSLSSVQNMVQTLVS-----VSRSDRLLKLDPLEQAK----LDLMS--AYALNSMFWMYLVTQGVNPKDHPIKQELERIRTYMNKVKEITDRRK----AAHIDKEAASRFVRNALWDADDKKRKDKTEHQQKGKHTKFTWS---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38801-1", "uniprot_id": "LRP1_YEAST", "id": "P38801-1", "name": "Exosome complex protein LRP1", "aln": "------------------------------------------------------------------------MEDIEKIKPYVRSFSKALDELKPEIEKLTS-----KSLDEQLLLLS-DERAK----LELINRYAYVLSSLMFANMKVLGVK-DMSPILGELKRVKSYMDKAKQYDNRITKSNEKSQAEQEKAKNIISNVLDGNKNQFEPSISRSNFQGKHTKFENDELAESTTTKIIDSTDHIRKASSKKSKRLDKVGKKKGGKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VXL4-1", "uniprot_id": "Q9VXL4_DROME", "id": "Q9VXL4-1", "name": "Nuclear nucleic acid-binding protein C1D", "aln": "-----------------------------------------------------------------MAQENQAVDNGLPCNAYLDTSLREDENMQHILKTFYSSIELLEADTEKALALQAERTLNTNEQIKLDSYLVYLNSTLFFIYLKLQGEDASNHAVMHDLRRTRDLLARDKKINDALA----APRLDMPAAKRFIAAGTHTRFVDMNGVMVSEKQYNKSKQETPK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :. ::.: : : : *. . : :.* . .* .:::: : * . . .: :*.* : : : *: : : : *..:: . : .* ", "identical_positions": 9, "similar_positions": 45, "identity": "3.37%" }, { "cls_id": "homologset.agr.SGD:S000001127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A401-1", "uniprot_id": "D4A401_RAT", "id": "D4A401-1", "name": "", "aln": "MTKKRK---RQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYNGGVKQSALLGLKDLLSQY-PCIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDVLLEHYPALITGR--SSILLKNFVELISHQQLSKGLVNRDRPQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADG---SSRLRESEGLQEQKETPHATSNSIFINWKDHANDQQQIQVYENGGSQPNVSSQFRLRYLVGTLGTVDEDPSSPENLKGFIEIIIPLLIECWIEALPP-QLAASVGSGVEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLSDFKHHFMTH----FPYALKEMTKQRKKETNKSIKH----CTVLSNNVDHLLLNLTLSDIMVSLAN---ASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNRDATENLIKAVYALYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSYLGSRNPELSTQLIDIIHTAASQANKDLLKNLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSQLSRCCIMGRLGSSLAGTLIGILYMRSSFSGWSHSVNDCLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVNEALLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWEVCVSILALLPRVLRLMLQSLRVNRASPEELPVVGQLLRLLLQHVPLRSHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3URQ0-1", "uniprot_id": "TEX10_MOUSE", "id": "Q3URQ0-1", "name": "Testis-expressed protein 10", "aln": "MTKKRK---RQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYSGGVKQSALLGLKDLLSQY-PFIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEHISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEHYPALITGR--SSILLKNFVELISHQQLSKGLVNRDRSQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADG---SSRLRESEGLQEQKETPHATSNSIFINWKDHANDQQQIQVYENGGSQPNVSSQFRLRCLG-TLGTVDEDLSSPENLKGFIEIIIPLLIECWIEALPP-QLAASVGSGVEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSH----FPYALKEITKQRKKDTNKSIKH----CTVLSNNVDHLLLNLTLSDIMVSLAN---ASTLQNDSSWIETIRKFVTETLKGGTRLNSKQLNRLLGVSWRLIQMQPNRDATENLIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSKVLSRWLAGLPLQLSYLGSRNPELSTQLIDIIHTAASQANKDLLKNLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSQLSRCCIMGRLGSSLAVTLIGILYMRSSFSGWSHSVNDCLMTDVDYLSFLFSTLTGFSKEELTWLQNLRGVPHVVQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVNEALLPFLASCCYSLLYFLLTLEKGDAEHLKKRDKLWEVCVSILALLPRVLRLMLQSLRVNRASPEELPVVGQLLRLLLQHVPLRSHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXF1-1", "uniprot_id": "TEX10_HUMAN", "id": "Q9NXF1-1", "name": "Testis-expressed protein 10", "aln": "MTKKRK---RQHDFQKVKLKVGKKKPKLQNATPTNFKTKTIHLPEQLKEDGTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQY-PFIIDAHLSNILSEVTAVFTDKDANVRLAAVQLLQFLAPKIRAEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEQYPALITGR--SSILLKNFVELISHQQLSKGLINRDRSQSWILSVNPNRRLTSQQWRLKVLVRLSKFLQALADG---SSRLRESEGLQEQKENPHATSNSIFINWKEHANDQQHIQVYENGGSQPNVSSQFRLRYLVGGLSGVDEGLSSTENLKGFIEIIIPLLIECWVEAVPP-QLATPVGNGIEREPLQVMQQVLNIISLLWKLSKQQDETHKLESWLRKNYLIDFKHHFMSR----FPYVLKEITKHKRKEPNKSIKH----CTVLSNNIDHLLLNLTLSDIMVSLAN---ASTLQKDCSWIEMIRKFVTETLEDGSRLNSKQLNRLLGVSWRLMQIQPNREDTETLIKAVYTLYQQRGLILPVRTLLLKFFSKIYQTEELRSCRFRYRSKVLSRWLAGLPLQLAHLGSRNPELSTQLIDIIHTAAARANKELLKSLQATALRIYDPQEGAVVVLPADSQQRLVQLVYFLPSLPADLLSRLSRCCIMGRLSSSLAAMLIGILHMRSSFSGWKYSAKDWLMSDVDYFSFLFSTLTGFSKEELTWLQSLRGVPHVIQTQLSPVLLYLTDLDQFLHHWDVTEAVFHSLLVIPARSQNFDILQSAISKHLVGLTVIPDSTAGCVFGVICKLLDHTCVVSETLLPFLASCCYSLLYFLLTIEKGEAEHLRKRDKLWGVCVSILALLPRVLRLMLQSLRVNRVGPEELPVVGQLLRLLLQHAPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFNVYITGHPQGPSALATVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803M3-1", "uniprot_id": "TEX10_DANRE", "id": "Q803M3-1", "name": "Testis-expressed protein 10 homolog", "aln": "MSKKRK---RQDDFQKTKLKVGKKKPKADNATNVNFRSKSIHLPEQLKHGESGPTTHRHLDIKDLLSQLHHFNSNVKQGALVGLRELLSAN-PTMVELHASVVLSEVAALFTDKDGSVRAAAVRLLRFVAQCIPSERVAPFFPLLSAHLTCAMTHISEAIQEEALRVLDVLLEHYPGLLSQR--HTVLLGNFLELISQRRKSGTGQDKSGKGSYALTVTTNRSVTAQQWRLTVLLRLSNFLQAVVEERPLEEGVSSRIGLG-MWAVEKGLVTPVDVTWEEHVNGQGKIQLFENSGAGPTSHSAYRLRPDSKSGAGMDKELCSAETVQGFAATLVPLLLEIWVEAAGGGRVQTDSGHLLSAESMALMFQILSILQLLRRMTPQRDQQDVLDAWFRNSYLTDFKQHFMKN----FPYGLLEVARHKKKADGKRIKQPVAAGVVAGSTVEPLAVNVTLCQVMVTLSLRGQDHVAAEDADWLGPIRVFIRETLSNGSKLSSKHLAALLEVVWRMIVTQRSRVVTDELLQAVYVQYQQRNLSVNVRSLLLRFFSQLY-IQEHQNHPHIARSRILARWLASLPVQLVQLGSRNPQLSAQLLETVQPAAARGNKDLLQSLQKNACSLYDPQEGCVVVLPVESQKRLVQILHFLPEFPAELLACLSEVCNTGRVSASLATTLIRTVHLRSPLSGCSSASQDVPLKDVDYLSFFFTTLTGFSSDMLRALQDKDEDDLLAASTLSPLSVYTTSLDQFLHHWDVVEVVCHCLDTLGSRAQCFDVIQNAIINNLAGLVVVPDCVCVALLRCVPRLLDVNFLPSDTLLHFLSDCCLSMLSLLLQLEQS----ARKRDAVWEACFAALSSVPRLLRLVLQSFRVLDLCEDELPVLAQILSLLLQHTQLRNHMMANASFLQHIIQDLTHYYGGESREQWLIDLLYCYSVTLSTHRAN-MGIRDIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38803-1", "uniprot_id": "IPI1_YEAST", "id": "P38803-1", "name": "Pre-rRNA-processing protein IPI1", "aln": "MTKSRKQKQKKQDFLRKKLKVGKPKEKARNATDTSFVSKTISIRNQHLDQNPHDLTKR-------LTLLKHHNINVRKETLTTFQKSIPS---IIKSRLMTPLLTQSIPLICDESQQVRQGLIDLVDEIG-SHDAEILKLHCNIFVLYINMAMTHIVTQIQADSTKFLSHLLKYCG--------DEVVRKSWVKLLNGVFGVLGWGQVGKNDSASIVQTKKRNAKYVTIHLNALYTLVEYGCQDERAR----------------------------------SDGDTAETTEDSGT------------------------------------------------------------------------------------------------LRNPYLIPDYPQPFEH----LKLFTRELKVQDATSSG----------------VNATLLSLATQDIDT--------RKAVFIEQFLPIVRKKIEVIIKEGGECGKSAN--------------------------------------KLKTLLAKIFD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3K4-1", "uniprot_id": "Q9W3K4_DROME", "id": "Q9W3K4-1", "name": "Pre-rRNA-processing protein Ipi1 N-terminal domain-containing protein", "aln": "MGGHHKKN-LRAEKAKVKLKG-AKLPKGLNVTKTDFKVRKIEIREQLKESSYSETGQRQFNLKETLSRLKHHSVKFRTDAQRNVRDSLKSGNADHLIGHLNELFQGIAAGALDMEGSARKESFKTLDVLLEALQPQAVAPFFHVIATYLRCAMTHVLPAIQEDSLLMLDVLLLRVPPAFLAERSASTIIGNFIDMISRAR-----HDNERSNRTLTLNLSQGKQTTVKWRTKVLIRLQQILSTLVTSKTPKSAAARVVHFEEMRPQYYNVLCPVRHDNRNLHAILNESKLTAEGTQ-----------------------------LHTYVEQLLPLLQDNWMEVRPQ--QQQPLLNQDAAASLHVVIGLMSLLWNLIEQHEAEHNTTELSDWLRKNYAQKFLLNFLDKDGSRFPYQQIPLATKNSSKDKGAVDG----------GELCMPQNLGIVQLACKFFP----TPVERQTQMFAHLIEYMHETLKRLNSLSPEQQ---------------------------------LSLVASLRALLFENATSLMKIVTEP---------LTSLLSASIDAYVSQRFTTREGVATRVLNLLCEIVERSD----------------------LYTHFGGEQRFTPFLSYLPQLLLKPTVGESTLRAMATLCRQLN-------------------------------GVFMAALVRSAPEIVSHLDKLQITGDIEGQEKFENQKRVLNLFYYARELDKEGKLERSVKQLEERVESKGIADYLKAVLGYN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* : : : *** * *.* ..* : * : :* . :* *: ::*.. .: : .:. : . :: . * . ..* . : : .: : . :. :: ****: ** :: .*. ** : .::.::. : : . : ..* * : : :. :*: * : : . : : : . .: :: . : : : :. . . :::** . ", "identical_positions": 31, "similar_positions": 90, "identity": "3.26%" }, { "cls_id": "homologset.agr.SGD:S000001128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZI7-1", "uniprot_id": "TSAP1_RAT", "id": "Q9QZI7-1", "name": "tRNA selenocysteine 1-associated protein 1", "aln": "---------------------------------------------------MAASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTG----------IPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKRFKLNYATYGKQP---------DNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQT-GVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVKPVEYS-QMYSYSYN--QYYQQ-YQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQT----------------------YEEVGDDAL---------------------------EDPAPQLDVTEAN------------------KEFMEQSEELYDALMDCHWQP---------LDTVSSEIPAMM----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VC6-1", "uniprot_id": "TSAP1_MOUSE", "id": "Q80VC6-1", "name": "tRNA selenocysteine 1-associated protein 1", "aln": "---------------------------------------------------MAASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTG----------IPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKRFKLNYATYGKQP---------DNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDPT-GVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVKPVEYS-QMYSYSYN--QYYQQ-YQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQT----------------------YEEVGDDAL---------------------------EDPAPQLDVTEAN------------------KEFMEQSEELYDALMDCHWQP---------LDTVSSEIPAMM----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX07-1", "uniprot_id": "TSAP1_HUMAN", "id": "Q9NX07-1", "name": "tRNA selenocysteine 1-associated protein 1", "aln": "---------------------------------------------------MAASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTG----------IPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKRFKLNYATYGKQP---------DNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQT-GVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRLSVAIPKASRVKPVEYS-QMYSYSYN--QYYQQ-YQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQT----------------------YEEVGDDAL---------------------------EDPMPQLDVTEAN------------------KEFMEQSEELYDALMDCHWQP---------LDTVSSEIPAMM----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KM14-1", "uniprot_id": "TSP1L_DANRE", "id": "Q4KM14-1", "name": "tRNA selenocysteine 1-associated protein 1-like", "aln": "------------------------------------------------MFNRMTSLWMGDLDPYMDENFIKQAFSTMGETAFGVKIITHRVTG----------GSAGYCFVEMADEASVDRCVQRLNGKLVPGSNPPRKFKLNYATYGKRP---------EPGPEFSVFVGDLTSEVDDYQLHQFFLKKFPSCKGAKVVTDPY-GNSRGYGFVKFSDENEQKKALEEFQNASGLGGKPIRISIAVNKGNKASTYHNQNNTYNTNYQQ-QYYRQPYNSYYPQWGYDQYSG-YNYGYNPYAAPPPMMGPPPPMGMPPMPPDMQGSTEAHDGTEEVEEDPS---------------------------EDPNPQVDVEELN------------------RQYMERSEELYDSLMECHWLP---------MDTITSDISMMNGS--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q503H1-1", "uniprot_id": "TSAP1_DANRE", "id": "Q503H1-1", "name": "tRNA selenocysteine 1-associated protein 1", "aln": "----------------------------------------------------MNSLWMGNLEPYMDEDFICRAFAQMGETVVKIRLIRDKITG----------KNAGYGFVELADDTAVERCLRKVNGKPLPGATPPKRFKLSRSNYGKQG---------ESS-TFSLFVSDLTPDVDDGMLYEFFHYHFSSCCSGKIVLDAN-GHSKCCGFVSFESEREQKRALVDLQGATGLGKKALRLSLASSRVNKKKESSEN-QIWQYHSDS-KNASFINQYYYPQNLSYLSTYDWNYSLDYLNPSQNTTPVDVTQ------------------SEQTEDDDL---------------------------EYPDSEINVTEAN------------------ETFMAQSEELYSALIGCFFQPPES------WDGVTCSASSYLPEPINQYEMEDSCSSNWVTT--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00539-1", "uniprot_id": "NAM8_YEAST", "id": "Q00539-1", "name": "Protein NAM8", "aln": "MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKN-GMLIPN-FPNKKLKLNWATSSYSNSNNSLNNV-KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGR-----AIKVGPTSGQQQHVSGNNDYNRSSSS-LNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPSSTCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLADTSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P31483-1", "uniprot_id": "TIA1_HUMAN", "id": "P31483-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "-----------------------------------------------MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKN-CKMIMDTAGN------------DPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP-FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKG-----------YSFVRFNSHESAAHAIVS------------------------VNGTTIEGHVVKCYWG----------------KETLDMINPVQQQNQIGYPQPYGQWG---QWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSMLPNQPSGYRVAGYETQ-------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*:*. : : : :: :* ::: . . * **:: . . .: * : . . . :. :**.**:.:: : * : .::* * * *: ***.* .. : : *: : . * . : . : . : : : . : : . * : . ", "identical_positions": 24, "similar_positions": 61, "identity": "4.51%" }, { "cls_id": "homologset.agr.SGD:S000001130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJS9-1", "uniprot_id": "RPF1_RAT", "id": "Q5RJS9-1", "name": "Ribosome production factor 1", "aln": "--MAKAGEKSGGGGKRGLKRKAPAEEPQETAVASDGTAESGVQSAKAAAFPPGFSISEIKNKQR----------------------------RHLMFTRWKQQQRKEKLAAKKK-LKRERE--ALGDKAP------PKPVPKTIDNQRVYDETTVD----PNDEEVAYDEATDEFASYFNRQTS--PKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRR-GLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSE-KKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKVCAYCSK-AI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TND5-1", "uniprot_id": "RPF1_MOUSE", "id": "Q7TND5-1", "name": "Ribosome production factor 1", "aln": "--MAKAGEKSVGGGKRGLKRKAAAEEPQEAAAASDGTAESGVQPAKAAAFPPGFSISEIKNKQR----------------------------RHLMFTRWKQQQRKEKLAAKKK-LKKERE--ALGDKAP------PKPVPKTIDNQRVYDETTVD----PNDEEVAYDEATDEFASYFNRQTS--PKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRR-GLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSE-KKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTS-RRKFHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y2-1", "uniprot_id": "RPF1_HUMAN", "id": "Q9H9Y2-1", "name": "Ribosome production factor 1", "aln": "--MAKAGDKSSSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQR----------------------------RHLMFTRWKQQQRKEKLAAKKK-LKKERE--ALGDKAP------PKPVPKTIDNQRVYDETTVD----PNDEEVAYDEATDEFASYFNKQTS--PKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRR-GLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSE-KKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTS-RRKFHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQU6-1", "uniprot_id": "RPF1_DANRE", "id": "Q6IQU6-1", "name": "Ribosome production factor 1", "aln": "---MKA-------------VKAPVEEMDQAECEVK---EE--KSASGPCFPPTFSVSEIKNKQR----------------------------RHTMFLKLKEEKRKKRMELKKK-KKKERK--ALDDKAP------PKEVPKTIENQRIYDETTVN----PEDEEVAFDEGTDEFSAYFNRLTN--PKVLITTSDRPRGRTVRFCDQLATVIPHAYVYYRR-GLALKKVIPQCISRGFTYLMVINEDRKVPNGMVLCHLPDGPTAHFKVSSVRLRKEMKRRGKNPTEHSPEVILNNFTTRLGHSIGRLFAALFPHDPQFVGRQVATFHNQRDFIFFRFHRYIFKNE-KKVGIQELGPRFTLKLRSLQKGTFDSKFGEYEWVHKRHEMDSS-RRKFHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38805-1", "uniprot_id": "RPF1_YEAST", "id": "P38805-1", "name": "Ribosome production factor 1", "aln": "--------------------MALGNEIN------------------------------ITNKLK----------------------------RQEIFADIKHEKNKERHTMRRKRAKEERENPELREQRL------KENVTQTIENTRVYDETIN--------KEVEGDE--DDLMRYFNSNSNEPPKIFLTTNVNAKKSAYEFANILIEILPNVTFVKRKFGYKLKEISDICIKRNFTDIVIINEDKKKVTGLTFIHLPEGPTFYFKLSSFVEVKKIVGHGR-PTSHIPELILNNFQTRLGQTVGRLFQSILPQNPDIEGRQVITLHNQRDYIFFRRHRYVFKDN-ERVGLQELGPQFTLKLKRLQRG----IKEETEWEHKP-EMDKE-KKKFYL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKB4-1", "uniprot_id": "RPF1_DROME", "id": "Q9VKB4-1", "name": "Probable ribosome production factor 1", "aln": "MIKIKRKTAPPPVEQDSDSDSSFDEEEPQDLEVQEGPVTDSSDEEAASSSKKTAKQGEASEDLKEEDDDDDEEENDDDDEEEDDDDDDDKKTRIPVLNPLSWMRNKEQRLALYKKMKKEKHKKKMQERRARRKAGVPANPGHTIESLREKDQTEVANLNDSDNEELQKELQLDDFSSYFERSYE--PKVLITFADNPVTKTRKFGLELSRIFPNALVKIRN-KSSVKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHLPNGPTAHFKLSNVKLTSDIKRDHKEITKHRPEVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRAVTFHNQRDYIFFRHHRYEFTKEGKRVKLRELGPRFTLKLRSLQEGTFDSKTGDYAWIISNKRHAMESRRRFFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* .:. : * :: . :.*:: * *.*:. : :: :**:. * *:* :*: : *:: **: . **:::* .. : .: * ::*. . *. :*:: . . ** ::::***:: .*: . ***:*** :**:*.. ..: : *.* **:***** **** ::**:: ::: ::*:: **:. *:*****:**** *** * .: ::* ::****:*****: **.* : * . . ", "identical_positions": 83, "similar_positions": 95, "identity": "20.91%" }, { "cls_id": "homologset.agr.SGD:S000001131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CY66-1", "uniprot_id": "GAR1_MOUSE", "id": "Q9CY66-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGSFRGGGGGGGGSFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGG---RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGG---FRGRGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYA1-1", "uniprot_id": "GAR1_RAT", "id": "Q6AYA1-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGG---------GGGGGGGGNFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGGGGGRGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGGG--FRGRGH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY12-1", "uniprot_id": "GAR1_HUMAN", "id": "Q9NY12-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGG-SSNHFRGG----------GGGGGGGNFRGGGRGGFGRG-GGRGGFNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGG------RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGGGFRGGR-GGG---FRGRGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVE0-1", "uniprot_id": "GAR1_DANRE", "id": "Q7ZVE0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGG------GGRGGGFNRGGGGG---RGG---------GFGGGRGGGFGGGRGGGFGGGRGGRGGFNRNQDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP-----PGEKGPP------RGGRGGGGG-RGGRGGGFRGGRGANGGGRGGF---GGRG-GGF-GGRG-----GGGGGFRGGRGGGGGRGFRGGR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVQ0-1", "uniprot_id": "GAR1_DROME", "id": "Q7KVQ0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MGFGKPRGGG------GGGGRGFGGGGGGGGRGFGG----------GGGGRGGGGGRGGGGGFGRGGGGRGGGRGAFDTGPPERVIPLGNYVYSCQNDLVCKVDIQD--VPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKLSDNVYANSFKPNQKLFIDPGKLLPIARFLPKP-----PQPKGAKKAFTNNRGGGGGGGG-FGGRGG----GRG--GGGRGGG---GGRGGGGFRGGAGRNGGGGGGGGFNRGRGGGGG-GGGGRGRW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28007-1", "uniprot_id": "GAR1_YEAST", "id": "P28007-1", "name": "H/ACA ribonucleoprotein complex subunit GAR1", "aln": "MSF---RGGN-----------------------RGG-------------------RGGFRGGFRGG---RTGSARSFQQGPPDTVLEMGAFLHPCEGDIVCRSINTK--IPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQATSFKEGDKFYIAADKLLPIERFLPKPKVVGPPKPKNKKK----RSGAPGGRGGASMGRGG----SRGGFRGGRGGSSFRGGRGGSSFRGGSR-------GGSFRGGSRGGSRGGFRGGRR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ***. ** * *** * * * : ***: *: :* :::.*:.::**: . :******::**** *:**:***:* :.: .::* .:.: *.*** :*::* . ****: ****:* * *. *. **** .** **** **** ..* ** ** *. * **. * ", "identical_positions": 82, "similar_positions": 46, "identity": "30.26%" }, { "cls_id": "homologset.agr.SGD:S000001132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NXR8-1", "uniprot_id": "ING3_HUMAN", "id": "Q9NXR8-1", "name": "Inhibitor of growth protein 3", "aln": "---------------------MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAK---KNKPEWRE-----EQMASIKKDYYKALEDADEKVQLANQIYDLVDR----HLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSSSS-------------LSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q498T3-1", "uniprot_id": "ING3_RAT", "id": "Q498T3-1", "name": "Inhibitor of growth protein 3", "aln": "---------------------MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAK---KNKPEWRE-----EQMASIKKDYYKALEDADEKVQLANQIYDLVDR----HLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKRKYNPTSHHTATDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQPLASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSSSS----------SSLSLCSSSSTVVQEVSQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSRHK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNL4-1", "uniprot_id": "ING4_HUMAN", "id": "Q9UNL4-1", "name": "Inhibitor of growth protein 4", "aln": "------------------MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSAR---SLSSEEKL-----ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDK----HIRRLDTDLARFEADLKEKQ-------------------------------------------------------------------------------------------------------------------------------IESSDYDSSSSK---------GKKK---------GRTQKEK-------------KAARARSKGKNSDEEAPKTAQKKL----------------------KLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WYH8-1", "uniprot_id": "ING5_HUMAN", "id": "Q8WYH8-1", "name": "Inhibitor of growth protein 5", "aln": "------------------MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVK---TLSPDQRV-----ERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDK----HIRRLDADLARFEADLKDK--------------------------------------------------------------------------------------------------------------------------------MEGSDFESSGGR---------GLKK---------GRGQKEK-------------RGSRGRGR-RTSEEDTPKKKKHK---------------------------GGSEF---TDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJY8-1", "uniprot_id": "ING5_DROME", "id": "Q9VJY8-1", "name": "Inhibitor of growth protein 5", "aln": "------------------MSSAIYLENYLDGLESLPTELERNFKLMRKLDDRAQTAMKSIDSHAKDFMRKLGENGAMSEDERR-----ERQEDIKALFGKAKEYSDDKVQLAIQTYELVDK----QIRRLDNDLARFEGEIQEKAS---------------------------------------------------------------------------------------------------------------------------STRAKSEEVVAKKGRKKTKDSKTTGKKKKSASSDEETGRGNNQSNANSSVNSSSNAGQGSKKKKSKVNQEKETRKGGAQKK----------------------TVEVDDSEK--ESCHTAATHPSDVMDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKCTQDRKKK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABZ3NNN7-1", "uniprot_id": "A0ABZ3NNN7_RAT", "id": "A0ABZ3NNN7-1", "name": "Inhibitor of growth protein", "aln": "MRGGNRHLKTEGRGRTAYLRGRPRYSGSLAATGAQPWPRGARREVAAHARSRARCTLGRFSSLRPHSASSAQGPLAAVLEAREGGAGSARWRQVEIGGLGGALSSGGRVPAAPGCRAEERRSWLLHVWLLDAEAAAAAAARSSSGGRMLGQ------------------------------------------------QQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDSNQKKRLQQHLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKSKMDSSQPERSSRRPRRQRTSESRDLCHMTNGIDDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDSEKTMDKSTEKTRKERRAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38806-1", "uniprot_id": "YNG2_YEAST", "id": "P38806-1", "name": "Chromatin modification-related protein YNG2", "aln": "------------------MDPSLVLEQTIQDVSNLPSEFRYLLEEIGSNDLKLIEEKKKYEQKESQIHKFIRQQGSIPKHPQE----DGLDKEIKESLLKCQSLQREKCVLANTALFLIAR----HLNKLEKNIALLEEDGVLAPVE-----------------------------------------------------------------------------------------------------------------------------EDGDMDSAAEASRESSVVSNSSVKK---------RRAASSSGSVPPTLKKKKTSRTSKLQNEIDVSSREKSVTPVSPS------------------------IEKKIARTKEFKNSRNGKGQNGSPENEEEDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIEMEKNKLKRKRN--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : . . . : .:: : * : :: *: : * . . . : . . . : ::. **:*::**:***:.**. :* ****: **.*. *:*.*:**.* .: ", "identical_positions": 28, "similar_positions": 44, "identity": "5.91%" }, { "cls_id": "homologset.agr.SGD:S000001133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FFR1-1", "uniprot_id": "F7FFR1_RAT", "id": "F7FFR1-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------------------------------------------MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKEEVADFQLSVDSLLENNSHKSQ----------------LDTQDQAQRLAEKLKCDTVVTAISAGPRTLNFKINRALLTKAVLQQVTEDGSKYGLKSELFSDLPQKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQANPLQHLFDVYVQVNKEATDDKN-------VTKLAHEFFHRLELGDTQALALWQRFRDLSIEEYTQIYKRLGIYFDEYSGESFYREKSQDVLKLLDSKGLLQKTAKGNVVVDVSETGDLSSVCTVMRSDGTSLYATRDLAAAIHRKDKYNFDTMIYVADKGQKRHFQQVFQMLKIMGHEWAERCQHVPFGIVKGMKTRRGEVTFLEDVLNEVQSRMLQNMASIKTTK-KMENPRETAEKVGLAALIIQDFRGLLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEET---FGCGYLNDFNVACLQEPQSVSILQHLLRFDEVLYTASQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPLAVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U186-1", "uniprot_id": "SYRM_MOUSE", "id": "Q3U186-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------------------------------------------MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKEEVADFQLSVDSLLEDNNHKSQ----------------VDTQDQARRLAEKLKCDTVVTAISAGPRTLNFKINRELLTKAVLQQVTEDGCKYGLKSELFSDLPKKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQTNPLQHLFDVYVQVNKEATDDKN-------VTKLAHEFFHRLEMGDTQALSLWQRFRDLSIEEYTQIYKRLGIYFDEYSGESFYREKSQDVLKLLDSKGLLQKTAEGNVVVDLSGTGDLSSVCTVMRSDGTSLYATRDLAAAIHRMDKYNFDTMIYVADKGQRRHFQQVFQMLKIMGYDWAERCQHVPFGIVKGMKTRRGGVTFLEDVLNEVQSRMLQNMASIKTTK-QLENPQETAERVGLAAVIIQDFRGTLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEET---FGCGYLNDSNVACLQEPQSVSILQHLLRFDEVLYLSSQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPDVAGARLHLFKAVRSVLANGMKLLGITPVCRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T160-1", "uniprot_id": "SYRM_HUMAN", "id": "Q5T160-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------------------------------------------MACGFRRAIACQLSRVLNLPPENLITSISAVPISQKEEVADFQLSVDSLLEKDNDHSR----------------PDIQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADDKS-------VAKAAQEFFQRLELGDVQALSLWQKFRDLSIEEYIRVYKRLGVYFDEYSGESFYREKSQEVLKLLESKGLLLKTIKGTAVVDLSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQKKHFQQVFQMLKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIQLRMLQNMASIKTTK-ELKNPQETAERVGLAALIIQDFKGLLLSDYKFSWDRVFQSRGDTGVFLQYTHARLHSLEET---FGCGYLNDFNTACLQEPQSVSILQHLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPVCRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVZ0-1", "uniprot_id": "A0A8M3AVZ0_DANRE", "id": "A0A8M3AVZ0-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------------------------------------------MACFFRRSAALQLAKACGQNEETLIPLISVAPVNKKQSVADLRVSVSHLLQSGAVRPD----------------GDLQNTTHTLARQIRTDAVVEEVIPGRGVIHFRLNKLLLAQKLLDQLRSDPDGFGVKSEILRRLRVGRTLVEFSSPNIAKKFHAGHLRSTIIGNFIANLKKALGNEVIRVNYLGDWGMQFGLLGSGFERFGSQEKLRTQPLEHLFEVYVQVNREAESDAS-------VRSAAAHFFRRLEQSEEQALELWRHFREITIHEYKRIYQRLGVEFDHYSGESFHRAETQTVLDELRSRRLLKTSQKGTGVVDLSDKGDMSNYATLVRSDGTSLYITRDVAAALDRKQRFSFDEMIYVTDKSQTMHFQQLFRILQAMGHPWAGSCHHVAFGLVQGMSTRRGEVLFLEDVLEEAQSRMIHNMRQSRTSK-ELEDPEVTAERIGISALIVQDFKGPLISDYRFEWDKVLQAQGDTGVFLQYTHARLCSLLRQ---QDC-EISCSDFSPLTDSRSVSLLQHLLRYDEVLLQCATDLQPKHLVNFLMTLSHLVASAHRELPVKGSSEAVAQARLCLFSSVRSVLANGMRILGITPVDKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38714-1", "uniprot_id": "SYRM_YEAST", "id": "P38714-1", "name": "Arginine--tRNA ligase, mitochondrial", "aln": "MFGIVYLKNRSLLCKNPFSSYPRYGFMPSFDTQFSNQFRKLEINIGRKRYSSKTLNTKYTDQPEGPIYPLDVLRLDISKALHDISGIDHSLILNALESTNSMDRGDLLLPLPKIKVADPVAVANRWAIELSTHGCIGKVCAKGPFLQFFLDQRYLIQSTVPNILLQKGKYGQK----KSRHQKKVVVEFSSPNIAKPFHAGHLRSTIIGGFLSNLYEAMGWSVTRMNYLGDWGRQFGLLAVGFKRYGDEKTLQKQPIQHLFDVYVKINMDLAKEEINGNSKCGISGEARSFFKNLENGDENAIKIWNRFRSLSIHHYIQTYSRLNINFDIFSGESQVSKESMNEALDIFRKNNLVKEIDGALVIDLTQWSKRLGRVVVQKSDGTTLYLTRDVGAAIERKKNLHFDKMVYVISSQQDLYMSQFFMILKKMNFEWAKDLQHINFGMVQGMSTRKGNVVFLDTILDEARDKALQIMENNKMKISQVDNPQRVADLIGVSAIIIQDMKSKRINNYEFNWNRMLSFEGDTGPYLQYTHSRLRSLERTSSDFTTDMLIHADFSNLNEPQLVELVRLLAQYPDVLRRAFETQEPATIVTYLFKVCHQVSSCYKKIWVSGKPADIAIPRLAVYSASRQVLHNAMSLLGLVPVDRM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : * * * :.. :. .: : *: *: . . * :. * :: . : : . ::* ::: * : : :: : :* * : :*******:** **.*********.*::** :*:* .* *:**:**** *****. **: :* ::.*: :*::***:***::* : .: : * **:.** .: :*: :*.:**.::*..* : *.**.: ** :**** :: : : * . .* *:*:: .. . .: :****:** ***:.**:.* .. ** *:** .. * ::.*.* :*: *.. ** :*: **:*:**.**:* * **: :*:* : : :: * . : . ::.:*. .*: :*::*:*:**::. :.:*.*.*::::. .**** :*****:** ** . : : : * :.: *.::: * :: :** . :* :*.:*:.:.* .: .:: : :.... :* .** ::.: *.** *.* :**:.*: ", "identical_positions": 168, "similar_positions": 205, "identity": "25.97%" }, { "cls_id": "homologset.agr.SGD:S000001134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS--PAIPSLRRT-----APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE----HQGFQLALLRRPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS--PAIPSLRRT-----APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE----HQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS--PVIPALKRS-----SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALG-------LLLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ----SSRVSWAEAWEPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS--PAETEIVDRG----EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG-------AGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN----KVN-VWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ-------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS--NSTSNEND----------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVG-------ALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV----DAS-VKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR--------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS--PALVSMTDR-----TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAG-------SFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ----ATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA--------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS--PALVSMTDR-----NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAG-------SFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ----ASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT--------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32467-1", "uniprot_id": "HXT4_YEAST", "id": "P32467-1", "name": "Low-affinity glucose transporter HXT4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIPKKPASAYVT---------------------------------------------------------------------------------------------------------------------------------------------------VSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFT-AVGLEDSFETSIVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWP---------------NGKKNGSSKGAGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYGYVFMGCLVFS-YFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQPFYKKMFGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . . . . :. : : : **: : : . : . .*:: *: * . *: .* :** * : * : : . : : : :*::* ::: ..* :: . : . . : : : :**. * . .: : :* : : :* :.. . . . :: **: * . * :. : ::: :: :.*:.::: .* : :. . .: .*. :: : : . :. : **:* : .:: ", "identical_positions": 30, "similar_positions": 107, "identity": "3.27%" }, { "cls_id": "homologset.agr.SGD:S000001136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR-TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALP------VPFLI-LMIIIPETPRWFVNRGQEERARKALKWLRGK--------EADVEPELKELMQSQADADRQATQNTCLELFK--RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA-HGPDVSHLG---------------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR-NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLGAALP------VPFLI-LMFLIPETPRWFVGRGLEERARKALKWLRGK--------EADVEPELKGLMRSQADADRQASRNTMLELLK--LNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT-YGPDVSHLG---------------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILP------LIFGA-IFFFMPESPTYLVSKDRSENAIKSIQWLRGK--------EYDYEPELAELRETDRETKANKVN-VWAALNR--PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLG---------------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVSWKTLSLLCLIIP------ILLLV-GLFIVPETPVYLLKNGKRSEANRALKWLWG---------DYCNTSNAIQAIQNDLDQTGVDAS-VKDLFSN--RASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR-HTDLSQSIG---------------------WLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NY64-1", "uniprot_id": "SL2A8_HUMAN", "id": "Q9NY64-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPEDPE-ETQPLLG--PPGGSAPRG-------------------------------------------------------------------------------------------------------------------------------------------------RRVFLAAFAAALGPLSFGFALGYSS------PAIPSLQRA-APPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPP------SLMLL-LMCFMPETPRFLLTQHRRQEAMAALRFLW-------------GSEQGWE----DPPIGAEQS-FHLALLRQ--PGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS-LASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQP----VDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPEDPQ-ETQPLLR--SPGARAPGG-------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPP------TLMLL-LMCYMPETPRFLLTQHQYQEAMAALRFLW-------------GSEEGWE----EPPVGAEHQGFQLAMLRR--PGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEP----ADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAP-ASPEEKARAGA---------------------------------------------------------------------------------------------------------------------------------------------LQNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS-SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPV------LVMIL-LLSFMPNSPRFLLSKSRDEEALQALIWLR------------ADSEVHWEFEQIQDNVRRQSSRVSWAEAWE--PRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTV--EIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYFLLAV------VPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UDF0-1", "uniprot_id": "GTR6_MOUSE", "id": "Q3UDF0-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRTEGLDYDTFPEVP-ATPGERERAGA---------------------------------------------------------------------------------------------------------------------------------------------LKNRRVFLATFAAVLGNFSFGYALVYTS------PVIPELKLS-SDPALHLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPDVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPV------LIMIL-LLSFMPNSPRFLLSKSRDEEALQALTWLR------------ADSEVHWEFEQIQDNVRRQSSRVSWAEARE--PRVYRPVLIAVLMRFLQQLTGITPILVYLQTIFDNTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASVMFAANLTLGLYVQFVPRPLTPNSTV--EIVTLGDT------AFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGQ3-1", "uniprot_id": "GTR6_HUMAN", "id": "Q9UGQ3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGT---------------------------------------------------------------------------------------------------------------------------------------------LQNKRVFLATFAAVLGNFSFGYALVYTS------PVIPALERS-LDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHG-LWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEAPV------LIMIL-LLSFMPNSPRFLLSRGRDEEALRALAWLRG-----------TDVDVHWEFEQIQDNVRRQSSRVSWAEARA--PHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQP2-1", "uniprot_id": "Q9VQP2_DROME", "id": "Q9VQP2-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMRLFQRPNCLLNRRN------------------------------------------------------------------------------------------------------------------------------------------------------------RYQLLTTLLINVISISHGIGIGWLS------PTLRKLQSDSPAGFEVKSEFEISWVGSMLGMGSVTGNILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQS-VEYLYVGRLLAGICGGGMYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYSIPLMVLILP------LWYLISVLLFIKESPMHLIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIMKIALTKGDALQDAVTFKDFYS--RPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGVAISLTAFGFFTKYAESHNIG-----------------------EYSWIPLLLMSMDIFLGNIGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQWGISATMWSCAGVTALSSLYFTYFMKETKGKSMLDD----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32465-1", "uniprot_id": "HXT1_YEAST", "id": "P32465-1", "name": "Low-affinity glucose transporter HXT1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLISPQKSNSSNS--------------------YELESGRSKAMNTPEGKNESFHDNLSESQVQPAVAPPNTGKG---------------------------------------------------------------------------------------------------------------------------------------------VYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPP------DHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGLS-DSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSS-----------------KGAGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLIS-FFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSLFSRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . . . :. : : * : : : : . .* : *: * *: .* :** : * : : . .. : : ::* :: . * :: . : : :*. * .. : :* : .* :... . : **: : . : . : : * :: : * : :. . .: . :: * : . .. : : **:* : : ", "identical_positions": 24, "similar_positions": 81, "identity": "2.59%" }, { "cls_id": "homologset.agr.SGD:S000001138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLALLR-RPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS----------------------------------------------------------------------LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLAMLR-RPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS----------------------------------------------------------------------GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS-SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ---SSRVSWAEAW-EPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTL--------------------------------------------------------------------TPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR-TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ---ATQNTCLELF-KRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA----------------------------------------------------------------------------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR-NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ---ASRNTMLELL-KLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT----------------------------------------------------------------------------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN---KVN-VWAALN-RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTG--IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ---------------------------------------------------------------------------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVS-------WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV---DAS-VKDLFS-NRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST---LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR----------------------------------------------------------------------------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6NWF1-1", "uniprot_id": "GTR12_DANRE", "id": "Q6NWF1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAPEESIRMTSDPQSKIYVQNPDTHIHLEQGPSAKSGNGRA--------------------------------------------------------------------------------------------------------------------------------------------------LVLCSVSVACLSGLLMGYEMSLIS------GALLQLRDV-----LTLSCPEQEQVVGSLLLGAFLLSLGGGTILDHYGRRFTIILTALLCVLGTLLSVCVVS-FWALVVGRMLVGMSVALSGTASCLYAAEVAPAAWRGRCVCVYELMVVLGMLLGFGLSWAFAGVP--DGWRFTFGGALLPALLQAGVMPLLPDSPRFLLAQQREKEAHATLLRLRAGIKEVEPVEDELRAIRLAMGAE---RLHGFLDLFQSRDNMLQRLLVGAALVFLQQATGQPNILAYASTVLSSVGFHGNEAATLASTGFGVVKVGGTIPAIFLVDKVGPKALLCVGVVVMMLSTATLGAITMQSRTHVSSLCRGPGNTANFTLFETGDETDIQTNTPLGLYQPQNKLKTNTFLTSINDTREHWILNHTYNHRTALMETAELSKKDSAKIALQSLHEVSPSLKWISLVSLLVYVAGFSISLGPMVHVVLSAIFPTGIRGKAVSVISAFNWATNLLISMTFLTLTERIGLPTVIFSYSAMSFLLVVFVIVFVPETKGRSLEQISKELAMKNHLRGTLLCHRRKHKATAQPSQEEKALATV----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38695-1", "uniprot_id": "HXT5_YEAST", "id": "P38695-1", "name": "Probable glucose transporter HXT5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELENAHQGPLEGSATVSTNSNSYNEKSGNSTAPGTAGYNDNLAQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKS---------------------------------------------------------------------------------------------------------------------------------------------DLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLE---DSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPN-----------------------------------------------------------------------------------GQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYG-YVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . . . :. : : : **: : : . . .*:: *: . : .* ** : * : : . : :*::* ::: ..* :: . . : : :** * .: : :: : .* :.. . . :: * : * . * . : .:: :: .*: :::. :* * .: .* ::: : . . :. : **:* : .:: . ", "identical_positions": 26, "similar_positions": 90, "identity": "2.63%" }, { "cls_id": "homologset.agr.SGD:S000001140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AII2-1", "uniprot_id": "A0A8I6AII2_RAT", "id": "A0A8I6AII2-1", "name": "", "aln": "---------------MSPLADSSAVALLWNDIFIMSQQGYVATPP----YSQSQPGMGISPPHYGHYGDPSHVSSPPGMMKPPG--PTGATAPSGLLPPGPLP-----------PGPPQFGPNGAHAAGHPPQRFP-GHPPVNN--AAPPYASGQPLPQSSYP-------GPGS--------TSSVTQLGSQFGSMQINNYGVGVTP---QGQGPPGP-----QSAGAFQGPPQPTQPSILQPGPQVPP-------PPPTAMNGP--GASPMSAPAHRQD-----GLPAPTPLNAQYQPPPPPGQT-----LGAGYHP-------------------QQANYGPQMGGAQLSYPGGFPGGP----------------AQMAGPAPQLQR--------------------------------KLDPDSIPSPIQVIENDRATRGGQVYTTNTRGQVPPLVTTECMIQDQGHSSPRYIRCTTYCFPCTSDMAKQAQIPLAAVIKPFADIPSNETPLYLVNHGESG-PVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDY-CRKNKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTVLKRLPKEEHEEKSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNE---NETVFAPVIQAGMEALKAAECP--GKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFPSQFVDVASLGLVPLLTGGSLYKYNVFQVHVDSQRFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCALLYTTIGGQRRLRIHNVALNCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKTIREILVNQTAHMLACYRKHCASPSAASQLILPDSMKVLPVYMNSLLKNCVLLSRPEISP-DERAYQRQLVMTMGVADSQLFFYPLLLPIHTLDVKS-----------------AALPPAVRCSESRLSEEGIFLLADGLNMFLWFGVGSPAELIQGIFNVPSFAHINTD---MTSLPEVGSPHSQQLRMIMNNIQQKKPY-SMKLIIVKQ--REQREMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94855-1", "uniprot_id": "SC24D_HUMAN", "id": "O94855-1", "name": "Protein transport protein Sec24D", "aln": "----------------------------------MSQQGYVATPP----YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAG--PLGATATRGMLPPGPPP-----------PGPHQFGQNGAHATGHPPQRFP-GPPPVNN--VASSHAPYQPSAQSSYP-------GPIS--------TSSVTQLGSQLSAMQINSYGSGMAP---PSQGPPGP-----LSATSLQTPPRPPQPSILQPGSQVLP-------PPPTTLNGP--GASPLPLPMYRPD-----GLSGPPPPNAQYQPPPLPGQT-----LGAGYPP-------------------QQANSGPQMAGAQLSYPGGFPGGP----------------AQMAGP-PQPQK--------------------------------KLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESG-PVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDY-CRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNE---NETVFAPVIQAGMEALKAADCP--GKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEIST-DERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKS-----------------TMLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTD---MTLLPEVGNPYSQQLRMIMGIIQQKRPY-SMKLTIVKQ--REQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3X972-1", "uniprot_id": "G3X972_MOUSE", "id": "G3X972-1", "name": "", "aln": "MNVNQSAPP------VPPYGQNQPIYPGYHQSSYGGQPGPAAPATPYGAYNGPVPGYQQAPPQGVPRAPPSSGAPPASAAQVPCGQTTYGQFGQGDIQNGPSST----AQMQRVPGSQQFGPPLAPVVSQPAVLQPYGPPPTST--QVTAQLAGMQISGAVAQ-------APPPSGLGYGPPTSLASASGNFPNSGPYGSYPQSQAPPLSQAQGHPGV-----QPPLRSAPPLASSFTSPASGGPQMPS-------MTGLLPPGQGFGSLPVNQANHVSS-----PPAPALPPGTQMTGPPVPPPPPMHSPQQPGYQL-------------------QQNGSFGPARGPQPNYESPYPGAPTF-------------GSQPGPPQPLPPK--------------------------------RLDPDAIPSPIQVIEDDRNNRGSEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESG-PLRCNRCKAYMCPLMTFIEGGRRFQCSFCSCVNDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDY-CKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDYLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVSESRAVITSLLDQIPEMFADTRE---TETVFAPVIQAGMEALKAAECA--GKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGTYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYACFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEENGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRAVLNSPVKTVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTT-DDRAYVRQLVSSMDVAETNVFFYPRLLPLTKSPLDS-----------------TAEPPAVRASEERLSSGDIYLLENGLNLFVWVGASVQQGVVQSLFNVSSFSQITSG---LSVLPVLDNPLSKKVRGLIDSLRAQRMR-YMKLIVVKQ--EDKLEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEG8-1", "uniprot_id": "B5DEG8_RAT", "id": "B5DEG8-1", "name": "", "aln": "MNVNQSAPP------VPPFGQNQPIYPGYHQSNYGGQPGPAAPATPYGAYNGPVPGYQQAPPQGVPRAPPCSGAPPASAAQVPCGQTTYGQFGQGDIQNGPSST----AQMPRVPGSQQFGPPLAPVVSQPAVLQPYGPPPTST--QVTAQLAAMQISGAVAQ-------APPPSGLGYGPPTSLASASGNFPNSGPYSTYPQSQAPPLSQAQGHPGV-----QPPLRSAPPLASSFTSPASGGPRMPS-------MPGPLPPGQGFGSLPVSQANRVSS-----PPAHALPPGTQMTGPPAPPPP-MHSPQQPGYQL-------------------QQNGSFGPARGPQPNYESPYPGAPTF-------------GTQPGPPQPLPPK--------------------------------RLDPDAIPSPIQVIEDDRNNRGSEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESG-PLRCNRCKAYMCPLMTFIEGGRRFQCSFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDY-CKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDYLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVSESRAVITSLLDQIPEMFADTRE---TETVFAPVIQAGMEALKAAECA--GKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGTYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYACFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRAVVSSPVKTVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTT-DDRAYVRQLVSSMDVAETNVFFYPRLLPLTKSPLDS-----------------TTEPPAVRASEERLSSGDIYLLENGLNLFVWVGASVQQGVVQSLFNVSSFSQITSG---LSVLPVLDNPLSKKVRGLIDTLRAQRTR-YMKLIVVKQ--EDKLEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53992-1", "uniprot_id": "SC24C_HUMAN", "id": "P53992-1", "name": "Protein transport protein Sec24C", "aln": "MNVNQSVPP------VPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSST----VQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSA--QVATQLSGMQISGAVAP-------APPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGI-----QTPQRSAPSQASSFTPPASGGPRLPS-------MTGPLLPGQSFGGPSVSQPNHVSS-----PPQ-ALPPGTQMTGPLGPLPP-MHSPQQPGYQP-------------------QQNGSFGPARGPQSNYGGPYPAAPTF-------------GSQPGPPQPLPPK--------------------------------RLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESG-PLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDY-CKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRE---TETVFVPVIQAGMEALKAAECA--GKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTT-DDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVES-----------------TTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSG---LSVLPVLDNPLSKKVRGLIDSLRAQRSR-YMKLTVVKQ--EDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PC99-1", "uniprot_id": "M9PC99_DROME", "id": "M9PC99-1", "name": "", "aln": "MNPNMYGPPPTQFQQQPQFGAPPPNSGGWPPQQQQLPQQQPPQQQLPPQQQQQQPQYGAPPPTSAASQPYLNGNYQQQLATSMGGLSVGGGVGGANPLKPPLPQGAPAAAAPPPTGFNQFNSNAAPPPTNNNNAAFGAPPPTQAGSYVNGALPPSSTPQSVASGINQMSLNSATLAGLPHMPPPKAATPGAAPGQPPIPAAGSTSQPPLPGQPPLPGQPPFSGQIPTSQPAPSPYGVPSSRPGQPQLPPGATPPTYTQPGLPPQQQQGIPPLQQPGIPQQQPGFPPQQPGLPPLSQPGLPPQPGAP-YGAPQQGGYSGGFPGQAPGGFPGAPPPLPGQQAAAPPQFGAPQPGYPGQQPGYPPQPGQQPMPGYPPQPGQQLGGPGYPPQPGAGFPGQPGRPGFNQPPMPGAGNMYQQAPQARRLDPDQMPNPIQVMIENQRLSGG-PFVTNQPGLLPPLVTTKFVVHDQGNSSPRFLRSSLYCIPNTGDLLKTTALPLTLNISPLAKVGEGEMEPPIVNFGEMG-PIRCNRCKAYMSPNMQFVDAGRRFQCLMCKVTSEVHQNYYQHLDHTGQRVDKHERPELLLGTYEFLATKDY-CRNNTPPEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQGQDKSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQEMFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKE---TETILYPAIQAGLEALKASNAA--GKLLVFNSTLPIAEAPGKLKNRDDRKLLGTDKEKTVLTPQTTAYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLIQDIIKNVSRPIAFDAVMRVRTSAGIRPTEFYGHFFMSNTTDVELASIDATKSISIEIKHDDKLAPEENVYLQVALLYTSCSGQRRLRILNLALRVTTTIADVFKCCDLDAMMLFFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISGGSDMTL-DDRSYVIQFILSMDLNQSVSYLYPRFIPIHNVVPEE-----------------TDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFVQSVFGVQGLQQIALER--FNIVPET--PLAKRIHGILEQIMKERSR-YMRITWLRQ--NDKLESVFRHFLVEDRGTDGSASYVDFLCHMHKEIKDLLSXHAGYSGTYKPEQRWADSYSQNRARMRRLSSMRSRLGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38810-1", "uniprot_id": "SFB3_YEAST", "id": "P38810-1", "name": "SED5-binding protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MSQQNILAASVSALSLDESTVH-------------------TGGASSKKSRRPHRAYHNFSSGTVP----------------------------------------------------------TLGNSPYTTPQLNQQ--------------DGFQQPQAFTPK-----QFGGFNNG------------------SGSVMSTPVMVSQERFGASEASSPYG-------------QSMLDMTAPQPTS----------------------------------------HIVPTQRFEDQAQYLQRSFETCRDSVPPLPTTQFYCVDQGSCDPHLMSLSMYNIPESEHLRAATKLPLGLTIQPFSTLTPNDAEVPTIPLPMDGTPLRCRRCRAYANPKFQFTYDSS-VICNICRVKMQVPGEHFAPMGPNGQRSDLNEKSELLHGTVDFLVPSIYNAIQEKELLPLHYVFLIDVSLLANENGSSLAMVEGVRSCIEYIS----DFQPNCEVAIIVYDNKLRFFNLRPDLDNAQEYIVSELDDVFLPFYNGLFVKPGNSMKIINDTLIKISGYISTDKYSHVPQVCYGSALQAAKLALDTVTGGQGGKIICSLNSLPTIGNGNLSLKRDNAHIAHVKCDN-------GFYKKLASDFLKSYISLDLYVTNAGFIDMATVGHPVEMTSGILKYYPHFQQETDAFTLVNDMVTNVSNIVGYQALLKVRCSTGLSVEQYYCDSSDNTDHDPIIPVLTRDTTLDVLLKYDSKIKTGTDVHFQTALLYTDIDGVRKVRSINTSGAVSNNIREIFKFINQNPVMRIMIKDVIKTLGDCDFVKIRRLIDDKMVEILTQYRG-LVSSNSSTQLILPDSIKTLPAYMLAFEKSELMKPNAQSTRGNERIYDLLKYDSLNSAQLCYKLYPQIVPFHVLLEETDLTFYDANDKLLQINSSSINNLSVRASHSNFINGGCYLIFQGDTIYLWFNENTNRMLLQDLLSVDESLPVSQISLFSGTLPETGTSINQKASNVIKNWQQVVNKSSLPLVLLRPNVDQYYSNVMSQLLCEDKTVNRIESYDNYLVIMHKKIQEKLQKDDFIKVSTAATHENIHQKFVQF---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . .: * * . . . * *: . .* : . .. * . : . : . :*** **. *** ..*: : : * :* : .: : :** *.*:: : : : * *:**.**:** * : * . * :* :* :: :. *:* * ::.** *: :::.. * . :.. ::*:**** ..* : . ::. :. :. . .*.::.*:. ::*:*::..* :.* :* :: ::*:*: :*:: : :* :* : :*. :: . :. ..:**. **.: **:: .:** . :**: :: .. :: *..*..: : .: *:: ::*:*::. :*.* : * ** . * ::.*: ::.. :.::*:::** *:*: ::: .. * :. : .:: : :*:*.:: .. :* *:*** * *::* * . . : :::: : :.:: : * . : :: : : ..:*: ** .*..:: *****:.:* ** * .. *. : .: : ::* * ::. : :** ::*: . : .**.:... . . ::: :* :::*.. .:*.::.* : :* . :: :: : : :: : . :: ::* **: ** ::* :**:* : *. ", "identical_positions": 136, "similar_positions": 293, "identity": "10.75%" }, { "cls_id": "homologset.agr.SGD:S000001141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M266-1", "uniprot_id": "A0ABK0M266_RAT", "id": "A0ABK0M266-1", "name": "", "aln": "MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEILHRIPTNEHLRPHTKNVLSVMFRFLETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQGIPENTVPPPE--------MVGMITT-----VAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIAIQVSAQA---------------RQHKLYNKELYADFIAAQIKTLSFLAYIIR--IYQELVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSE---QESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAAEA-ALPGVPTAPAAPGPAPSPAPVPAPPPPPPPAPAPATPVTPAPVPPFEKQGEKDKEDKQTFQVTDCR-----------------SLVKTLVCGVKTITWGITSCKAPGEAQFIP--------NKQLQPKETQIYIKLVKYAMQALDIYQVQ------IAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLERLPEMG-SNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNP--ADSISHVAYRVLGKFGGSNRKMLKESQRLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYRRQAWEVIRCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPSVIISHRYKAQDTPAR-------KTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLP--LTWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLMRCATPLKDEERAEEIVVAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSALTK----LPCYKSLPSLVPLRIAALNALAACN------YLPQS--REKIIAALFKALNSTNSELQEAGEACMR-KFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNESLSECGRCSLSPFCQFEPAVEGVEEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSNMRLDLQFQAIKIISIIVKNDDAWLANQHSLVSQLRRVWVSETFQERHR--KENMAATNWKEPKLLAFCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVE-FNDPNFGDELKAKVLQHILNPAFLYSFEK-GEGEQLLG-PPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHD---NNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSGGEGVNSVS--IKRGLSVDSAQEVKRFRAATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWCK-SELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLNFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATSANPSQLFGTLMILKSACCNNPSYIDRLISVFMRSLQKMVREHLNPQ---AASGSTEATAAGASELVMLSLDLVKTRLAVMSMEMRKNFIQTILTSLIEKSPDAKILRAVVKIVEEWVKNN-SPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDEALSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGSHFWIKQCIELLLAVCEKSTAIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPMRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLPIKPKQTAEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEFGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWRVNMYRGYLAICHPEEQQLS--FIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLG-RNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSVFMWRQHHYQ-----------AIVTAYENSSHHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLESIFVKE-RQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSV-----------GNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN--VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFS-AQTAEVEIPGEFLMPKP-THYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQIPALGWEDFVQGCVERQEAAVLAPPQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTG-----------------KLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVSRCFAQPNFKVDGILKTVLRDEIIAWHKK-TQEDTSSALSAAGQPENMDSQQLVSLVQKAVTAVMTRLHNLAQFDGGESK-VNTLVAAANSLDNLCRMDPAWHPWL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YV3-1", "uniprot_id": "TRRAP_MOUSE", "id": "Q80YV3-1", "name": "Transformation/transcription domain-associated protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKFVKRSIFL----------------------------HLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSALTK----LPCYKSLPSLVPLRIAALNALAACN------YLPQS--REKIIAALFKALNSTNSELQEAGEACMR-KFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNE-------------------------MKICSAIINLFHLIPAAPQTLVKPPLEVVMETERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMGATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSSSTSNMRLDLQFQAIKIISIIVKNDDAWLASQHSLVSQLRRVWVSETFQERHR--KENMAATNWKEPKLLAFCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVE-FNDPNFGDELKAKVLQHILNPAFLYSFEK-GEGEQLLG-PPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHD---NNKNRNSKLRRLMTFAWPCLLSKACVDPACRYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHPIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVS--IKRGLSVDSAQEVKRFRAATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWCK-SELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLNFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATSANPSQLFGTLMIHKSACCNNPSYIDRLISVFMRSLQKMVREHLNPQ---TASGSTEATAAGTSELVMLSLDLVKTRLAVMSMEMRKNFIQTILTSLIEKSPDAKILRAVVKIVEEWVKNN-SPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDEALSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGSHFWIKQCIELLLAVCEKSTAIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPMRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLPIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEFGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEEQQLS--FIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLG-RNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSVFMWRQHHYQ-----------AIVTAYENSSHHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLESIFVKE-RQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSA-----------GNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN--VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFS-AQTAEVEIPGEFLMPKP-THYYIKIARFMPRVEIVQKHNTAARRLHIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASH--------------------------QVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTG-----------------KLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGVLKTVLRDEIIAWHKK-TQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFDGGESK-VNTLVAAANSLDNLCRMDPAWHPWL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4A5-1", "uniprot_id": "TRRAP_HUMAN", "id": "Q9Y4A5-1", "name": "Transformation/transcription domain-associated protein", "aln": "MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRFLETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIPENTVPPPE--------MVGMITT-----IAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIAIQVSAQA---------------RQHKLYNKELYADFIAAQIKTLSFLAYIIR--IYQELVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSE---QESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAVEA-ALPGVPTAPAAPGPAPSPAPVPAPPPPPPP-PPPATPVTPAPVPPFEKQGEKDKEDKQTFQVTDCR-----------------SLVKTLVCGVKTITWGITSCKAPGEAQFIP--------NKQLQPKETQIYIKLVKYAMQALDIYQVQ------IAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMG-SNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNP--ADSISHVAYRVLGKFGGSNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPAR-------KTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLP--LTWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSALTK----LPCYKSLPSLVPLRIAALNALAACN------YLPQS--REKIIAALFKALNSTNSELQEAGEACMR-KFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNESISECGRCPLSPFCQF-------EEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDLQFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHR--KENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVD-FNDPNFGDELKAKVLQHILNPAFLYSFEK-GEGEQLLG-PPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHD---NNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVSSSIKRGLSVDSAQEVKRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWPK-SELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLSFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQ---AASGSTEATSG-TSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKSPDAKILRAVVKIVEEWVKNN-SPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEEQQLS--FIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLG-RNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQGKPTWSGMHSSSIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKE-RQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSD-----------------------------PGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN--VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFS-AQTAEVEIPGEFLMPKP-THYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASH--------------------------QVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTG-----------------KLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKK-TQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESK-VNTLVAAANSLDNLCRMDPAWHPWL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ITC5-1", "uniprot_id": "TRRAP_DANRE", "id": "A0A0R4ITC5-1", "name": "Transformation/transcription domain-associated protein", "aln": "MSFVPTPSPTVVDQTTLMKKYLQFVAALTDNNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPTQQLRKLVLEIIHRIPTNEHLRSHAKNILSVMFRFLEIESEENVLICLRIIIELHKQFRPPISQEIHHFLDFVKQIYKELPKVVARYFENPQVIAENTVPSPE--------MVGMITS-----VMVKTAPERDDSETRTHTIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVSEFVPLIMNTIMLQVSPQA---------------RQHKLFNKELYADFIAAQIKTLSFLAYIIR--IYQDLVGKYSQQMVKGMLQLLSNCPPETAHLRKELLIAAKHILTTDLRSQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQNLPLTDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSE---QENGNGRDILMRMLEVFVLKFHTIARYQLVSIFKKCKPQSEMGVVDTGALPGVPATPTVTTPALPP-------------PAPPTPVTPAPPPATSFDRAGEKEDKQTFQVSDCR-----------------SLVKTLVCGVKTITWGITSCKAPGEAQFIP--------NKQLQPKETQIYIKLVKYAMQALDIYQVQ------IAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANLTTSALFATILVEYLLERLPEMG-SNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQSAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNP--AETISHVAYRVLGKFGGSNRKMLKESQKLLYVVTEVQGPSIKAEFTDCKASIQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMTSLEDNKHSLYQLLAHPNFTEKWIPNVIISHRYKAQDTPAR-------RTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQSGSQPSTGMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLP--LIWVLQNQLTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLIRCATPLKDEEKTEELLSAQDKSFHLVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTIIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVMEHKVFYTELLNLCEAEDAALMK----LPCYKSLPSLVPLRIAALNALAACN------YLPQS--REKIIAALFKALNSTNSELQEAGEACMG-KFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRGDGSPAMEG------------------VEEMRICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDAKPLRDVLASNPNRFVPLLVPAGSAATVRPGSPSTSTARLDLQFQAIKIISIIVKNDEGWLAGQHSLVSQLRRVWVSEAFQERHR--KDNMAATNWKEPKLLAFCLLSYCKRNYSEIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYGITHKRALFFRFVE-FNDPHFNDELKAKVLQHILNPAFLYSFEK-GEGEQLLG-PPNPEGDNPESITSVFITKVLDPEKQADLADSLRIYLLQFSTLLVEHAPHHIHD---NNKSRNSKLRRLMTFAWPCLLPKTCVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHTMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFRVYYPVRHHLVQHMISAMQRLGFTPSVTIEQRKLAVDLAEVVIKWELQRIKDQQPESEADPGSVGEGTSGASAAMKRGMSVDSAQDVKRFRTAAGAVGTVFGRSQSIPGTEALLTKPVEKQHTDTVVNFLIRIACQVNDSTNVAGSPGELLSRRCVNLMKTALRPDMWPS-SELKLQWFDKLLMTVEQPNQANFSNICTGLEILCFLLSVLQPPAILSHFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSTFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKASSANPTQLFGTLMILKSACSNNSSYIDRLISVFMRSLQKMVREHLSPQ---PNPG-AAETSTVTSELVMLSLDLVKMRLSVMNMEMRKNFIQVILTSLIEKSPDPKILRAVVKIVEEWVKNSGNPMATNQVPNPREKSILLVKMMTYIEKRFPDDLELNAQFLDLVNYVYRDDNLSGSDITSKLEPAFLSGLRCTQPLIRAKFFEVFDASMKRRVYERLLYICCSQNWESMGSHFWIKQCTELLLAVCERNTTIGTSCQGSMLPSITNVINLADSHDRAAFAMATHIKQEPRERENSETKEEDVEIDIELAPGDQTSLPKTKEQAERDAGNQLHMLTNRHDKFLDSLREVKTGALLNALVQLCHISTPLAEKTWVQLFPRLWKILSDRQQHALSGEMGPFLCSGSHQAQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWLRSTLMLEQQAFEKGLNLHIKPKQSTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFPETSTAIAYEQHGFFEQAQETYEKAMEKARKEH---NVSPAIFPEYQLWEDHWIRCSKELNQWEPLTEYGQSKGHNNPYLVLECAWRVSNWAAMKEALVQVELSCPKEMAWKVNMHRGYLAICHPEEQQLN--FIERLVEMASSLAIREWRRLPHIVSHVHTPLLQAAQQIIELQEAAQINAGLQPANLG-RNTSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQ-----------AIVTAYENNTQHDPNTNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKD-RQPHLGVSSITCYLHACRHQNESKSRKYLAKVLWLLSFDD-KNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKPLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSA-----------AAQTHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN--VSTMFSSAASESLARRAQATAQDPVFQKMKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFS-AQTAEVEIPGEFLMPKP-THYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASH--------------------------QVLRDILKEVQGNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGLAEFMLHLNRLNPEMLQIAQDTG-----------------KLNVSYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKAVLRDEIIAWHKK-TQEDTSMPLSPAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESK-VNTLVAAANSLDNLCRMDPAWHPWL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I8U7-1", "uniprot_id": "TRA1_DROME", "id": "Q8I8U7-1", "name": "Transcription-associated protein 1", "aln": "---------MSVIENVPVNTFRNYLNILNDSSSKDELKLKATQELSEHFEMIMQSPAYPSFLDNSLKIFMRILQDGEPQFIQENTMQHIRKLILEMIHRLPITESLRQHVKTIITMMLKILKTDNEENVLVCLRIIIELHKHFRPSFNSEIQLFLGFVKEIYTNLPNHLTSIFETSNDVWVTDLKDLN--------LEVLLSESYSVRTIHVEKALDSNSQQQIYNLLPRGILSLKVLQELPIIVVLMYQIYKNAVHQEVSEFIPLILTTINLQPTVTR---------------RNS--PQKEIYVEFMGAQIKTLSFLAYIVR--IFQEVVIASSLSVTSGMLNLMKNCPKEAAHLRKELLIAARHIFATDLRQKFIPSIEQLFDEDLLIGKG-VTLDSIRPLAYSTLADLAHHVRQSLNIDVLIKAVNLFSKNVHDESLAVGIQTMSCKLLLNLVDCLRHHSE---TEPQRSKALLSKLLKVFVKKFETIAKIQLPLIIQKCKGHAFSGALVNSSGNASLSHINAP--------------------------DLKDDISNIQVSASGSQWIYSVNVAEFR-----------------SLVKTLVGGVKTITWGFFNSKFQLTDTKLAN------HEKIFGPEIVCSYIDLVYYAMEALDIYTIN------VNPNQQR----TSGLISRSKEEKEVLEHFSGIFLMMHSQNFQEIFSTTINFLVERIYKNQSLQVIANSFLANPTTSPLFATVLVEYLLNKMEEMG-SNLERSNLYLRLFKLVFGSVSLFPVENEQMLRPHLHKIVNRSMELALISEEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLEGLNRLQSGFHKQHMRDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSPTLISQGLRTLELCVDNLQPDFLYDHIQPVRAALMQALWKTLRN---QDNAALVAFRVLGKFGGGNRKMMVEPQALSYIINDKPTISIVTYFQEYETPIDFPVDEAIKSAFRALGSNSTDQFYRRQSWEVIRCFLAAFISLDDEKHMLLKLFTHVDFVENKIMN-WSTFQHKAGNETVR-------ETHQTALIGMLVASATKDLRDSVCPVMAAVVRHYTMVAIAQQAGPFPQKGYQ---------------ATHGIDPMILIDALASCMGHEEKELCKPGIACMGIILDTATNIMGNKDRACKLPIIQYLAEKMVSLCYDRPWYSKVGGCQAIQFLCKHMS--LRALFQNLFNFLKAFMFVLMDLEGDVSNGAIEITKSYMKSMLEICLTPINECYKNIDLKDLQAKATYEVIHELVRHITSPNTIVREESMVLLKHIGTIQSKTVSEVMDPHKDVLADIIPPKKHLLRHQPANAQIGLMDGNTFCTTLEPRLFTIDLTNTYHKLFFHELLTLSEAEDATLAK----LDCYKNVPNLIPLRTSALRALAACH------YISDIGYKEKIINIIFKVMESDKSELQTTAFHCMK-HFITGVTLEKEKVQSAMRPLLLKLGDHRNLSIPAIKRLSYFTQIFPQMFNEKLSEQILQHCSKIMEIFVSEYKSTSPNVNFFASSKGG-----------------EYEQKIVILIEMFFYISASVKYIEK-LCQLVLKTEKNLMIEASSPYREALIKFLQRFPTETVDLFLTESLMIDPQWNRLFIYLLKHETGVSFRAVIKS--SRYNNLIHYLNTHTEFP------EALKYEIQHQAVLIIFTLMESDDQWIPTRQDIVDALKNCWQ--NYLSTLS--SEDVLCDLWH---LIGKILLHYFSNNTNDIELLFQLLRALCFRFIPDVYFLRDFLQHTVAQSFTVNWKRNAFFYFVENFNNSFLSEELKAKIITAVIIPCFAVSFDK-GEGNKLIGAPPTPYQEDEKNIVSVFINKVFDPDKQYD--DAVRIALLQLACLLVERASQHIHDGDANNKRQGNKLRRLMTFAWPCLLSKSSVDPTARYHGHLLLSHIIARLAIHKKIVLQVFHSLLKGHALEARSIVKQALDVLTPAMPLRMEDGNTMLTHWTKKIIVEEGHAMQQLFHILQLIIRHYKVYFPVRHQLVQHLINYMQRLGFPPTASIEHKKLAVDLAEVIIKWELHRIKD---DRETKTDGTEEELIQESSVKRSGIDLVETRK-KSFDIIRETTVQGVG-SHTKP---DDILRSIDKSYCDTVLNFLIRLACQVNDPQAPILSPGESLSRRCVMLLKMAMRPEIWPQPFDIKLNWLDKVLATVETP-HHNLNNICTGIDFLTFLTTILSPDQLVSIIRPVQRGLSLCIIHQNTRIVRLMHMFLTRIMAIFPPDT-----QHKHEDLDLLYTAVSKMIAENLTSYEKSPQPNASSLFGTLMILKACTTNNASYIDRILVQFIRVLNHLTRDHINTIGGNTVISQSPDSNALPLELLVLSLELIKNRIFVMSVEIRKLFIGTILVSLIEKSTEVKIIKCIIKMLDEWIKTK-EPNVMTQVPSIREKSALLVKLMQNVEKKFTDEIELNIQFLEIINFIYRDEILKQTELTNKLEGAFLNGLRFQNPNVRSKFFEILDSSMRRRLHDRLLYIICSQAWDTIGSHYWIKQCIELLILTANTMMQIQCSNEQFKIPSITSVIPVNSSETQENSFVSFLSSHSESFDIIQTVDDKDDVYDIDLNADRKEDCQQILPNRR----VTLVELVYKQAEFLEANRNIRTDQMLVATSQLCHIDTQLAQSVWLSMFPRIWSIFTEDQRCNITKELIPFLSSGTNVNQKDCHPSTLNTFVESLTKCAPPIYIPPNLLAYLGKSHNLWHRAILVLEDMAVNQSMQSKDIDGGENQFSDLD--VQQSNNIFDSLSKMYSSMHEEDLWAGLWLKFAHYPETNIAVSYEQMGFFEEAQGAYDLAMTKFKQDLSNGVVNTYVNSELLLWENHWMRCAKELNQWDILLDYAQTNKDKNMFLILESSWRVPDWNLMKIALAKTEQCYLKHYGFKINLYKGYLSILHQEERQTG--NIERYVEIASSLCIREWRRLPNIVSHIHLPYLQASQQIMELHEASQIHQGLAQS----RNNSLHDMKAIVKTWRNRLPIISDDLSHWSDIFTWRQHHYQ------------IITQHLE---QQSDQGSTMLGVHASAQAIISFGKIARKHNLTGVCQETLSRIYTIPSVPIVDCFQKIRQQVKCYLQMPSTSGKNEINEALEVIESTNLKYFTGEMNAEFYALKGLLLAQIGRSEEAGKSFSVAAQLHDGLTKAWAMWGDYMEQIFLKE-RKITLAVDALICYLQASRNQIESKTRKYIAKVLWFLSYDNNTKILISTLEKHVAGIPPSYWLPWIPQLLCCLEQFEGDVILNLLSQIGRLYPQAVYFPIRTLYLTLKIEQREKHKTAEQAVKSSCSNIDGTTLSFGRGASHGNIPSINPIKATPPMWRCSKVMQLQREVHPTILSSLEGIVDQMVWFRESWTEEVLRQLRQGLIKCYAIAFEKRDTVQHSTITPHTLHFVKKLGSTFGIGIENVPGSVTSSISNSAASESLARRAQVTFQDPVFQKMKEQFTNDFDFSKPGAMKLHNLISKLKTWIKVLETKVKKLPTSFLIEDKCRFLSNFS-QKTAEVELPGELLIPLS-SHYYVRIARFMPRVEIVQKNNTAARRLYIRGTNGKIYPYLVVLDSGLGDARREERVLQLKRMLNYYLEKQKETSRRFLNITVPRVVPISPQMRLAEDNPNSISLLKIFKKCCQSMQVDYDMPIVKYYDRLSEVQARGTPTTH--------------------------TLLREIFSEIQWTMVPKTLLKHWALKTFLAATDFWHFRKMLTLQLALAFLCEHALNLTRLNADMMYLHQDSG-----------------LMNISYFKFDVNDDKCQLNQHRPVPFRLTPNVGEFITHFGITGPLSAAIVATARCFIQPNYKLSSILQTILRDEIIALQKKGFRECKLIEGSEDRYSDGNCMEHSVNIVNSAVDIIMTRFNKISYFDSIENKKISVLVQSATNIDNLCRMDPAWHPWL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38811-1", "uniprot_id": "TRA1_YEAST", "id": "P38811-1", "name": "SAGA complex/NuA4 acetyltransferase complex subunit TRA1", "aln": "--------------MSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLKEVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMKVLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADELLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQLTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQIKATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYKKLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTGYLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLN-RQYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDINDSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIHDLKVFNPPPNEYTVANPKLWASVSRVFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSPETTKKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDSGLLHVAQSFLTSEITSPNFAGILLRFLKGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLFPNINEVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVLLQSLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQGLRTLELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRNRQFLKPPTDLTEKTELDIDAIADFKINGMPEDVPLSVTPGIQSALNILQSYKSDIHYRKSAYKYLTCVLLLMTKSSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLEPTVNKRDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHFCLLQVNTTLLNKRNYNGTFN--------IDLKNPNFMLDSSLILDAIPFALSYYIPEVREVGVLAYKRIYEKSCLIYG-EELALSHSFIPELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVLKDTQSEAPSAITDSAEKLLIDLLSITFADVKEE-------DLGNKVLENTLTDIVCELSNANPKVRNACQKSLHTISNLTGIPIVKLMDHSKQFLLS--PIFAKPLRALPFTMQIGNVDAITFCLSLPNTFLTFNEELFR---LLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIALKNEEFATAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLKPLLMNLSDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDLAEQMP------------------------TKIIVSIINIFHLLPPQADMFLNDLLLKVMLLERKLRLQLDSPFRTPLARYLNRFHNPVTEYFKKNMTLR--QLVLFMCNIVQRPEAKELAEDFEKELDNFYDFYISNIPKNQVR--------VVSFFTNMVDLFNTMVITNGDEWLKKKGNMILKLKDMLNLTLKTIKENSFYIDHLQLNQSIAKFQALYLRFTELSERDQNPLLLDFIDFSFSNGIKASYSLKKFIFHNIIASS-NKEKQNNFINDATLFVLSDKCLDARIFVLKNVINSTLIYEVATSGSLKSYLVEDKKPKWLELLHNKIWKNSNAILAYDVLDHHDLFRFELLQLSAIFIKADPEIIAEIK----------KDIIKFCWNFIK---LEDTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLVKQSLDVLTPVLHERMNAAGTPDTWINWVKRVMVENSSSQNNILYQFLISHPDLFFNSRDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWENKTLEITN-VNNTKTDSDGDVVMSDSKSDINPVEADTTAIIVDANNNS----------------------PISLHLREACTAFLIRYVCASNHR-----AIETELGLRAINILSELISDKHWTN-VNVKLVYFEKFLIFQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKSDHHDVQEALQKVLQVIMKAIKAQG---------VSVIIEEESPGKTFIQMLTSVITQDLQETSSVTAGVTLAWVLFMNFPDNIVPLLTPLMKTFSKLCKDHLSIS--QPKDAMALEEARITTKLLEKVLYILSLKVSLLGDSRRP--FLSTVALLIDHSMDQNFLRKIVNMSRSWIFNT------EIFPTVKEKAAILTKMLAFEIR---GEPSLSKLFYEIVLKLFDQEHFNNTEITVRMEQPFLVGTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQNWEFIADYPWLNQALQLLYGSFNREKELSLKNIYCLSPPSILQEYLPEN-----------------------AEMVTEVNDLELSN-----------------------FVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYHTRQISSRTNVINMLLDSISKIES-LELPPHLVKYLAISYNAWYQSINILESIQSNTSIDNTKIIEAN----------------EDALLELYVNLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQVKA-----RSGALPYSQSEYALWEDNWIQCAEKLQHWDVLTELAKHEG--FTDLLLECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKTFLALQNFAESRKGDQEVRKLCDEGIQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEATQIYANLHTTTVQNLDSKAQEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVINN----AYLPLIPALQQSNSNSNINTHAYRGYHEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQN-----MNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYEEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKIRELLCRILWLISIDDASGMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTTKEDFAVIQRQTMAVMGDKPDTNDR-----------------------NGRRQPWEYLQELNNILKTAYPLLALSLESLVAQINDRFKSTTDEDLFRLIN-------------VLLIDGTLNYNRLPFPRKNP---------------------KLPENTEKNLVKFSTTLLAPYIRPKFNADFIDNKP---DYETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLLNKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVR-HSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLNAAHDDALPAPDMT------------------------ILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSN----------LHRPIIENPQLREMVQTNVDLIIRKVAQLGHLNSTPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: : : ** * . *** ::. *** :* ::*:: : * : *.:*** :* . *.. .*: ** :.:. ** . : : :*: :**.: . ..*: : .: : . .: : ::. ::***: *.*::.*:: :. *: . .:: *: :: ::::* .: * . : :*::*. :.. . : : *: *: : :: .**:* .* ::* *. . ..: * : * :: :::: . : : ..: : . . : . : :: ..: *: : .:: *: : : . * : .: **:::: . : *:.:: . : . *: *: . * . : : :: :: . : .. . *. :. : .* : .:.: . . * * .*: *** : :::: .. * : : ::.*.* : *. : .:*: :::*::: : *:* *** :**:. :*** :*:*:: :***.: **: . * . * :: * : : :: * ::: *. ::.::: *::: * .. . : : **:**:.::: ** : :: : .... : * :. : .:. :: **** .* *. : *. *.: ::. : . * . ::** :::*.* : . ..::.* .: . ::. : .:*. : *: : : . :: .* :* : .: .: : .* : : **. . :.:.: . : : * .. * :: ::: :.:: ::*:. . . : . :*: * ::. :: ::. . * : :. **::* : :::: :::: .*: .. *. :**: :*.*:: : : .*. * ::: :: :: :. :::* ::* .** * * : :* :*: ::* *:.* : :** *: .* *: :..: *::*. :** : : . *. : .. . *::* :. : :: .: :. :: : :: : .. . .*: :**:::. :.. :: : .: .:*.. : * ..:...:* ::::::: . : : * :: **. ::* * :: :** : .:. *:* ::* ::***:: *** : .::.** .::*** *::::** *: * * . . .* ***::*::*:::*::*: * : .: : *:**..***.:* : ** : . . : ::.: :*:: : * : . :.: : . .*.: :* ** : * *:. ** :*: **:** .* : :.. :::* ::::**:*** **:. *..:. **** :* ::. : :. : * * * .* :.::***:.: .*. . *:**:*:*.: * :.* *:*:*.**: * ** .*:**..*** ** .***::***::*::: ***.::*:.*.*:. *.**** ** : : : :: .: :. .:: ***:*. :** *: :.::**::* *: . * .:.:.. :* *:.:***** .* *.. : ::: ::.: ****::* :** : : **: * ..: :: : :* : ***.:* *: :. :* * :* : : ...:. : * * :* .*. :. : :: :*. ** . * . .. *.:*: * : ** * .: .. :* * .**** : ::*:**: *: . ::::****:* *::*: ::: *** *** :*.::.: * : .:*****::** *::* *.*. ** :* : :.:* .:.:***:*: :*. . :* :*.:: * . .: * *:* .: . :.. : :*:..:* :** .:**. * *:* *** :: * : : .. : :.. ... : : : :* : . :.: . :. :.*********: .:: .: * ::. :.: :*.: :*: ::. * .:*****: .: :. .. *. . : :::: :: .: : : :* . **.* * : **:", "identical_positions": 442, "similar_positions": 890, "identity": "10.91%" }, { "cls_id": "homologset.agr.SGD:S000001144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2W1-1", "uniprot_id": "STK25_MOUSE", "id": "Q9Z2W1-1", "name": "Serine/threonine-protein kinase 25", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLR---GFA----HQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKN--NPPTLEG--HHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKK-TSFLTELIDRY--------KRWKSEGHGEE-SSSEDSDIDGEAEDG--EQGPI--------------------WTFPPTIRPS----------------------------------------------------------------------------------PHSKLHKGTALHSSQKPAEPIK--RQPRSQCLSTLVR-----PVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQR------------FSHSRNHLTSTR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6V9V9-1", "uniprot_id": "Q6V9V9_RAT", "id": "Q6V9V9-1", "name": "Serine/threonine-protein kinase 25", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLR---GFA----HQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKN--NPPTLEG--HHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKK-TSFLTELIDRY--------KRWKSEGHGEE-SSSEDSDIDGEAEDG--EQGPI--------------------WTFPPTIRPS----------------------------------------------------------------------------------PHSKLHKGTALHSSQKPAEPIK--RQPRSQCLSTLVR-----PVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQR------------FSHSRNHLTSTR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00506-1", "uniprot_id": "STK25_HUMAN", "id": "O00506-1", "name": "Serine/threonine-protein kinase 25", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLR---GFA----NQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKN--SPPTLEG--QHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKK-TSFLTELIDRY--------KRWKSEGHGEE-SSSEDSDIDGEAEDG--EQGPI--------------------WTFPPTIRPS----------------------------------------------------------------------------------PHSKLHKGTALHSSQKPAEPVK--RQPRSQCLSTLVR-----PVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQR------------FSHNRNHLTSTR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDG3-1", "uniprot_id": "A0A8M2BDG3_DANRE", "id": "A0A8M2BDG3-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLQ---NIR----NQNSRLNPEEYFTKLERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YVTKYYGSYLTGSKLWIIMEYLGGGSALDLLRP-GTLEEVYIATILREILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DFKADIWSLGITAIELAKGEPPNAELHPMRVLFLIPKN--NPPTLEG--SYSKAFKDFVEACLNKEPRFRPTAKELLKHKFITRYTKK-TSYLSELIDRY--------RRWKSEGHGEE-SSSDDSDMDGEGDDR--DQGPM--------------------WTFP-TVRPS----------------------------------------------------------------------------------TINKLNRG-LSHLDNKTSDVMK--RQPKSSSLTSFIT-----PIFKELKEKRRVGGNGVCAVEELENAFSLAEESSPGISDRLLNHVMERVCR------------FTLNGNSLPLKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99KH8-1", "uniprot_id": "STK24_MOUSE", "id": "Q99KH8-1", "name": "Serine/threonine-protein kinase 24", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHSPVQSGLP---GMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKN--NPPTLEG--NYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKK-TSYLTELIDRY--------KRWKAE-QSHEDSSSEDSDVETDGQASGGSDSGD--------------------WIFT-IREK-----------------------------------------------------------------------------------DPKNLENGTLQLSDLERNKMKDIPKRPFSQCLSTIIS-----PLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR------------YSLSGGGASAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0LT89-1", "uniprot_id": "STK24_RAT", "id": "B0LT89-1", "name": "Serine/threonine-protein kinase 24", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHSPVQSGLP---GMQTLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKN--NPPTLEG--SYSRPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKK-TSYLTELIDRY--------KRWKAE-QSHEDSSSEDSDVETDSQASGGSDSGD--------------------WIFT-IREK-----------------------------------------------------------------------------------DPKNLENGTLQPSDLERNKMKDFPKRPFSQCLSTIIS-----PLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR------------YSLSGGGASAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6E0-1", "uniprot_id": "STK24_HUMAN", "id": "Q9Y6E0-1", "name": "Serine/threonine-protein kinase 24", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY---DSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKN--NPPTLEG--NYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKK-TSYLTELIDRY--------KRWKAE-QSHDDSSSEDSDAETDGQASGGSDSGD--------------------WIFT-IREK-----------------------------------------------------------------------------------DPKNLENGALQPSDLDRNKMKDIPKRPFSQCLSTIIS-----PLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR------------YSLSGGGTSSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99JT2-1", "uniprot_id": "STK26_MOUSE", "id": "Q99JT2-1", "name": "Serine/threonine-protein kinase 26", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHSPVAVQVP---GMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSS-YVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAY---DSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKN--NPPTLIG--DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK-TSYLTELIDRF--------KRWKAEGHSDEESDSEGSDSESSSRES--NPHPE--------------------WSFTTVRKKP----------------------------------------------------------------------------------DPKKLQNGE--EQDLVQT----------LSCLSMIIT-----PAFAELKQQDENNASRNQAIEELEKSIAVAETACPGITDKMVKKLIEKFQK------------CSADESP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZV99-1", "uniprot_id": "A0A8I5ZV99_RAT", "id": "A0A8I5ZV99-1", "name": "Serine/threonine-protein kinase 26", "aln": "MFSGVSKIAQKRKMSAIKPDDLRLSPRTQMVEREDQYLNCEKFQPGHSTTDSLRTSYVPGFSIPAFCCSPQPLRAPCFANSDYFSQPGLQLEASAPLTPPGSGVEAGPTAEPPPAASQPRRSGGLLGRLHLLFLKRRGAAEPHHWSPGPSHCRTHSSAFRKRSGTATVRKLGGRASERPRSRSLGELQSYPRRRSQSVPQEPPPQKQREVAAASMAHSPVAVQVP---GMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSS-YVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAY---DSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKN--NPPTLVG--DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK-TSYLTELIDRF--------KRWKAEGHSDEESDSEGSDSESSSRES--NTHPE--------------------WSFTTVRKKP----------------------------------------------------------------------------------DPKKLQNGEVCEQDLVQT----------LSCLSMIIT-----PAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQK------------CSADESP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P289-1", "uniprot_id": "STK26_HUMAN", "id": "Q9P289-1", "name": "Serine/threonine-protein kinase 26", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHSPVAVQVP---GMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSS-YVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAY---DSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKN--NPPTLVG--DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK-TSYLTELIDRF--------KRWKAEGHSDDESDSEGSDSESTSREN--NTHPE--------------------WSFTTVRKKP----------------------------------------------------------------------------------DPKKVQNGA--EQDLVQT----------LSCLSMIIT-----PAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQK------------CSADESP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38692-1", "uniprot_id": "KIC1_YEAST", "id": "P38692-1", "name": "Serine/threonine-protein kinase KIC1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTKPQNSKQG----LAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRP-GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYY--DTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKS--KPPRLEDR-SYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSKPSEAPKPSQNGGGDEAQKSIASNDNEIKRVNEGDVEMKWDFDSLSSSDYIIENNINLDALAEDNNEWATAQHDLFNYAYPDEDSYYFDPTSHNTRPFVYQGTTIGKGYPGTIAQNSTLNAPVTNNYTNSKYPSKMVAGTTNTSGTHTAGPMTSSKRLESKAPKQLLELFEDNEIITAENDVNTEAPKISKSISSLNAGNSSRDDFIPSISNEVNGNINNNKMRPHLPPLSSGNNYYSQSTPALPLLQTKFNKTSKGPPTSGLTTAPTSIEIEIPEELPNSALPTPASADPVLIPSTKARSSTVTAGTPSSSSSIQYKSPSNVPRRLTVSNNRPEHCPSTITNQKLGSAVASNSGISSTPNNSNNYNNNTDSENSRGSSGSNTANSTQMGITNPGNVTKLSTHKASSPSRPLFGVGTSPNRKPAGSPTQNIGHNST-----HTNLAPPPTMKPMANSKDNKDILLQPLNSIPSSSTLNTISGNSSNNLTSSNYFSNEKEGSRVNGDFKRNNPNLKLQMPLPTPVVRNKLLDPNTATSQNNNGMPGSAGISTNENINQFG-------------------------------FNTSSASNIPVSMTPISEKHIDFGGKIKRSQSISNRKNSSASEHPLNILGSSVSGNVSGIGNNNVGSNNNSGPNNSVPLSANTGNTTIKANSTTIATSSSAAASTTAPISQQTIPSGTQFNHILSSAATAANSVNSLGFGMCPPPQSLQMEMFLDLESFLPGKQRRVDRKPQVLKELENLLQMFEEGLPCIEHALKEQLISTPIKDNEH---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZBH7-1", "uniprot_id": "A1ZBH7_DROME", "id": "A1ZBH7-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAHSHHNAN-MLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLE-PSDDIQIIQQEIIMMRDCRHP-NIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSL--RVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPAQNHTLKTG----------MTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGG---------------AAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMGFG-MGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPITSSISSSASSASFYNRLLLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKHELDALPQAATKSAGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPPKRSHKRRHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMNELHDAAIDQLFPRRTTWLYVIKDVLMSLSGKSCQLYRHDLVALHSKQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVRKAMNGCLKLELINMNSASWFHSEDLEYDAMATMVPRRDLLKVVRVHQVEKDAILVCYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCLPDSVLAFHKHGMQGKSLRNGEVTQEIKDMSRTYRLLGSDKVVALESQLLRTGSLGSEEGHDLYILAGHEASY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .. : : ** *.:* *:*. :: .: ***::.*: .*::: :*:** .: . : *:**** .*** **. .*** .: . * : * *. : :* * .*. :*. :*****.**:*::: *:***.****:.*:. * :*::: ***:****** : ***: ***: *:* :** ::..::.: *: *. .** * . : .:::*: .* ::* * :*. **: *: .**:.:: . : . :. * * : :: . * . ..::. . ", "identical_positions": 90, "similar_positions": 112, "identity": "6.15%" }, { "cls_id": "homologset.agr.SGD:S000001146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04828-1", "uniprot_id": "AK1C1_HUMAN", "id": "Q04828-1", "name": "Aldo-keto reductase family 1 member C1", "aln": "---------------------------MDS-----KYQCVKLNDGHFMPVLGFG-------------------------------------------TYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE-------------------EVIPK--------DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGSHREEPW---VDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS-DEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52895-1", "uniprot_id": "AK1C2_HUMAN", "id": "P52895-1", "name": "Aldo-keto reductase family 1 member C2", "aln": "---------------------------MDS-----KYQCVKLNDGHFMPVLGFG-------------------------------------------TYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE-------------------EVIPK--------DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGSHREEPW---VDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS-DEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42330-1", "uniprot_id": "AK1C3_HUMAN", "id": "P42330-1", "name": "Aldo-keto reductase family 1 member C3", "aln": "---------------------------MDS-----KHQCVKLNDGHFMPVLGFG-------------------------------------------TYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE-------------------ELSPT--------DENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKS-KDIVLVAYSALGSQRDKRW---VDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE-FQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYS-DEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17516-1", "uniprot_id": "AK1C4_HUMAN", "id": "P17516-1", "name": "Aldo-keto reductase family 1 member C4", "aln": "---------------------------MDP-----KYQRVELNDGHFMPVLGFG-------------------------------------------TYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE-------------------TPLPK--------DENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKS-KDIVLVAHSALGTQRHKLW---VDPNSPVLLEDPVLCALAKKH-KQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFE-FQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFS-DEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23457-1", "uniprot_id": "DIDH_RAT", "id": "P23457-1", "name": "3-alpha-hydroxysteroid dehydrogenase", "aln": "---------------------------MDS-----ISLRVALNDGNFIPVLGFG-------------------------------------------TTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGD-------------------IFFPR--------DEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKS-KDIILVSYCTLGSSRDKTW---VDQKSPVLLDDPVLCAIAKKY-KQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFE-FQLASEDMKALDGLNRNFRYNNAKYFDDHPNHPFT-DE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AD50-1", "uniprot_id": "A0A8I6AD50_RAT", "id": "A0A8I6AD50-1", "name": "", "aln": "---------------------------MAASCHYWAMALFKIQSSEYVNQISFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCSPGVSASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIKAGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKSGD-------------------NDFPV--------DEKGKSLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSKLLDYCKS-KDIVLVAYGALGTQRYKEW---VDQNSPVLLNDPVLCDVAKKN-KRSPALIALRYLVQRGVVPLAQSFKENEMRENLQVFD-FQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPFS-EEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCX1-1", "uniprot_id": "AK1D1_MOUSE", "id": "Q8VCX1-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------------------MNLS---AAHHQISLSDGNNIPLIGLG------------------------------------------TYSDPRPVP-GKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGK-------------------EIYPR--------DENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTNQVECHPYFTQTKLLKFCQQ-HDIVIVAHSPLGTCRNPSW---VNVSSPPLLNDELLTSLGKKY-NKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFD-FSLTEEEMKDIDALNKNVRYVELLMWSDHPEYPFH-DEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31210-1", "uniprot_id": "AK1D1_RAT", "id": "P31210-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------------------MNLS---TANHHIPLNDGNSIPIIGLG------------------------------------------TYSDPRPVP-GKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGE-------------------EFYPK--------DENGRVIYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGTCRNPLW---VNVSSPPLLKDELLTSLGKKY-NKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFD-FSLTKEEMKDIEALNKNVRFVEMLMWSDHPEYPFH-DEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51857-1", "uniprot_id": "AK1D1_HUMAN", "id": "P51857-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------------------MDLS---AASHRIPLSDGNSIPIIGLG------------------------------------------TYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD-------------------EIYPR--------DENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQ-HDIVITAYSPLGTSRNPIW---VNVSSPPLLKDALLNSLGKRY-NKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFD-FSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFH-DEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCT1-1", "uniprot_id": "AKCL2_MOUSE", "id": "Q9DCT1-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "--------------------------------------------MENIPTVGLG----------------------------------------------TWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGE-------------------KDIPL--------DRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHK-RNVSVTAYRPLGGSG----------GGFHLMDDTVIRKIAKKH-GKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFD-FELTEKDMEELLSLDKNLRLATFPTTENHQDYPFH-IEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U1Y4-1", "uniprot_id": "AKCL2_RAT", "id": "Q5U1Y4-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "--------------------------------------------MHQIPTVGLG----------------------------------------------TWKASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGD-------------------KDIPL--------DRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHG-RNVSVTAYRPLGGSR----------DGVHLMDDIVIRKIAKKH-GKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFD-FELTEKDMEELLSLDKNLRLATFPSTENHKDYPFH-IEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96JD6-1", "uniprot_id": "AKCL2_HUMAN", "id": "Q96JD6-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "--------------------------------------------MGDIPAVGLS----------------------------------------------SWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPL--------DESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQS-RDVSVTAYRPLGGSC----------EGVDLIDNPVIKRIAKEH-GKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFD-FELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFH-IEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JRZ8-1", "uniprot_id": "AK1BF_HUMAN", "id": "C9JRZ8-1", "name": "Aldo-keto reductase family 1 member B15", "aln": "-----------------------------------MATFVELSTKAKMPIVGLG----------------------------------------------TWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD-------------------DFFPK--------DDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS-KGITVTAYSPLGSPDRP-W---AKPEDPSLLEDPKIKEIAAKH-KKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFD-FKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFD-AEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PF61-1", "uniprot_id": "ALDR_DROME", "id": "M9PF61-1", "name": "Aldo-keto reductase 1B", "aln": "MNTLMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAPKVVCLDGNEIPVIGLG----------------------------------------------TFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGC-------------------DLFPT--------DKDGKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA--TIPPVTNQIECHPYLTQKKLIDFCKS-KDITITAYSPLGSPNRP-W---AKAGDPVILEEAKIKEIAAKK-KKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFD-FELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38715-1", "uniprot_id": "GRE3_YEAST", "id": "P38715-1", "name": "NADPH-dependent aldose reductase GRE3", "aln": "-----------------------------------MSSLVTLNNGLKMPLVGLG----------------------------------------------CWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVP-----------------FEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLR--GCRIKPVALQIEHHPYLTQEHLVEFCKL-HDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTWLDGKFPTFA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.:. **. :: :* * * : ::* .: : * *.::* *:* . . * :* *.* *:* :. * : * : . ::. :* ** * :*****: :: :* *: *:* * *:.: ::. . :.:: .:* ::.: : :. . : . : :*: ** : * . .: :: . * *: .:: : .:: * : .: ", "identical_positions": 42, "similar_positions": 84, "identity": "9.72%" }, { "cls_id": "homologset.agr.SGD:S000001148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TY86-1", "uniprot_id": "AIFM3_MOUSE", "id": "Q3TY86-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF03-1", "uniprot_id": "D3ZF03_RAT", "id": "D3ZF03-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNIGTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSS-TNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDIENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NN9-1", "uniprot_id": "AIFM3_HUMAN", "id": "Q96NN9-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3R9-1", "uniprot_id": "A0A8M2B3R9_DANRE", "id": "A0A8M2B3R9-1", "name": "", "aln": "-------------------MEAKQCKE----------------------------------------VTEMVCLESDLQDGQMKEVLVDENKILLVRNNGEFTAVGGLCSHYGAPLIKGTLIGDRVRCPFHGACFNTKTGDIEEFPGLDCLPKFKVKVDGGKVYVTSDQK--NLKKRVKKMSSRVPGVN-----HTVVLIGGGPASLQCAETLRQNDYGGRIVMVTKDEQLPLDKTKLSKAMNIEIEKVLLRQSDFLQQYGIEVWTKKEVKSVDTDAKTVTFQDGTLQNYDQLLISTGGRARPLECPGAELENVKLLQTYEDASEIHRISAGKKAVIVGTSFIGMEVAAYLSDKAASVTVIGTSKFPFQASLGSDIGKMTMQMLEEKNVKFYTSNGVAEIRGENGKVKEVVLKNGEVLPADIIIAGIGVIPNSDFLKETLVEIDSHKAVVVDKFMKTNIPDVFAAGDVVSFPLTLVGHKRVNIGHWQLAQAHGRIAGLSMLNRQVEINTVPYFWTMLLGKSIRYTGYGEGYTEIVFKGSTEERKFLAFYIKDEEVVAAASLNFDPAVARLAEMLLMGKRITK-------AQAQSDNLSWLQLP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38816-1", "uniprot_id": "TRXB2_YEAST", "id": "P38816-1", "name": "Thioredoxin reductase 2, mitochondrial", "aln": "------------------------------------------------------------------MIKHIVSPFRTNFVG-ISKSVLSRMIHHKVTIIGSGPAAHTAAIYLARAEMKPTLYEGMMANGIAAGGQLTTTTDIENFPGFP-------------------------------------------------------------ESLSGSELMERMRK---------------------------QSAKFGTNIITETVSKVDLSSKPFRLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQQGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAEFLTKYASKVYILVRKDHFRASVIMQRRIEKNPNIIVLFNTVALEAKGDGKLLN-MLRIKNTKSNVENDLEVNGLFYAIGHSPATDIVKGQVDEEETGYIKTVPGSSLTSVPGFFAAGDVQDS-------------RYRQAVTSAGSGCIAALDAERYLSAQE----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. * : : :. * *. * . : . . :* .* . : .. * *:*:***: *:* . *: : .* * :: :: : . :*. . ::::.*. .: : * : : : .. : .: .::* . . * * :*:. * .* :: .. : . . ::: .. . .:: ::::. : : : .: . .** * :.::: :: * *.:*..*****. ::: * : . . * : :.: ", "identical_positions": 40, "similar_positions": 110, "identity": "6.61%" }, { "cls_id": "homologset.agr.SGD:S000001149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42208-1", "uniprot_id": "SEPT2_MOUSE", "id": "P42208-1", "name": "Septin-2", "aln": "--------------------------------MS----------KQQPTQFINPETP------GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAE---------SDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSE------------------------RLKRGGRKVEN----EDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDSDSGALGQHV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y81-1", "uniprot_id": "SEPT2_RAT", "id": "Q91Y81-1", "name": "Septin-2", "aln": "--------------------------------MS----------KQQPTQFINPETP------GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINSRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAE---------SDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSE------------------------RLKRGGRKVEN----EDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDTDSSTLGHHV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15019-1", "uniprot_id": "SEPT2_HUMAN", "id": "Q15019-1", "name": "Septin-2", "aln": "--------------------------------MS----------KQQPTQFINPETP------GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAE---------SDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSE------------------------RLKRGGRKVEN----EDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGHHV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHR7-1", "uniprot_id": "Q0KHR7_DROME", "id": "Q0KHR7-1", "name": "Septin", "aln": "MKHQPPPPPLPLSQPPTMGATAAGGVASVISTMNGSSSSGIEAVKCRPPIYPKPKTPSFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIEKTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCEDSWRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECD---------SDEDDDFKQQDRELKASIPFAVVGSNTILEVA-GKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCIS----------QISQHALRERGKLKRDSISSTNGFDAAISETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMKKNDSVIDV------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32468-1", "uniprot_id": "CDC12_YEAST", "id": "P32468-1", "name": "Cell division control protein 12", "aln": "--------------------------------------------MSAATATAAPVPP-------PVGISNLPNQRYKIVNEEGGTFTVMLCGESGLGKTTFINTLFQTVLKRADGQQHRQEPIRKTVEIDITRALLEEKHFELRVNVIDTPGFGDNVNNNKAWQPLVDFIDDQHDSYMRQEQQPYRTKKFDLRVHAVLYFIRPTGHGLKPIDIETMKRLSTRANLIPVIAKADTLTAQELQQFKSRIRQVIEAQEIRIFTPPLDADSKEDAKSGSNPDSAAVEHARQLIEAMPFAIVGSEKKFDNGQGTQVVARKYPWGLVEIENDSHCDFRKLRALLLRTYLLDLISTTQEMHYETYRRLRLEGHENTGEGNEDFTLPAIAPARKLSHNPRYKEEENALKKYFTDQVKAE-EQRFRQWEQNIVNERIRLNGDLEEIQGKVKKLEEQVKSLQVKKSHLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * .* :*::.**:* :: :.* **:*: *******:*:**:** * * *.:*.::: . :**: ..**:.*:****:** :* ...:: .:**:*. *: :*. * : * ***. :**: * **.*: :*: :: : :.*:: **.*** *. :* .::*.** : :* : *::: * *: *. :: * * ::**::***: :: *.:* .* ****:*::*: .* ** ***::*: *:: ** ..**::***.:* :*.:. : .*:: : : .:*: :: :.. : ::: . : . ", "identical_positions": 106, "similar_positions": 128, "identity": "23.09%" }, { "cls_id": "homologset.agr.SGD:S000001150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0H9-1", "uniprot_id": "GGA1_MOUSE", "id": "Q8R0H9-1", "name": "ADP-ribosylation factor-binding protein GGA1", "aln": "--------------MEPAMEP-----ETLEARINRATNPLNKELNWASINSFCEQLNEDF-EGPPLATRLLAHKIQSP---QEWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKSKILELLYSWTVCLP----EEVKIAEAYQMLKKQGIVKSDPKLPED-AIFPLPPPRPKNVIFED--EEKSKMLARLLKSSHPEDLRAAN-----KLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQG-AASSSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATASSIPGSTS--------ALLDLSGLD-----------LPPPGTTQPATPTR---------PGNQSSPEQLS------------ASVSLLDDELMSLGLSDPTPPS--GTSSDSVGWDNFQ----SSDGTES--------SVPPPAQAPSMDCRPPAQAPPP-----------TSSGLDDLDLLGKTLMQQALP------PEAQQVRWEKQQPAPRLTLRDLQSKSS---------------SPSPGAASLLHTTSPEPPGPPPQATP---------TEFSLTSITVPLESIKPSSILPVTVYDQHGFRVLFHFARDPL-------------------PGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLIFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLY6-1", "uniprot_id": "A0A8I6GLY6_RAT", "id": "A0A8I6GLY6-1", "name": "", "aln": "--------------MEPAMEP-----ETLEARINRATNPLNKELDWASINGFCEQLNEDF-EGPPLATRLLAHKIQSP---QEWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLP----EEVKIAEAYQMLKKQGIVKSDPKLPED-AIFPLPPPRPKNVIFED--EEKSKMLARLLKSSHPEDLRAAN-----KLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQG-AASSSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEELNGEATAGSIPGSTS--------ALLDLSGLD-----------LPSSGTTYPATPTR---------PGNQNSPEQLS------------ASVSLLDDELMSLGLSDPTPPS--APSSDSVGWNGFQ----SSDGTEP--------SVPPPAQAPCMDSRPPAQASPP-----------TSSGLDDLDLLGKTLMQQALP------PEAQQVRWEKQQPAPRLTLRDLQSKSS---------------SPNPGATSLLHTTSPEPPGPQPQAIP---------TELSLTNITVPLESIKPSSILPVTVYDQHGFRVLFHFARDPL-------------------PGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLIFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJY5-1", "uniprot_id": "GGA1_HUMAN", "id": "Q9UJY5-1", "name": "ADP-ribosylation factor-binding protein GGA1", "aln": "--------------MEPAMEP-----ETLEARINRATNPLNKELDWASINGFCEQLNEDF-EGPPLATRLLAHKIQSP---QEWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLP----EEVKIAEAYQMLKKQGIVKSDPKLPDD-TTFPLPPPRPKNVIFED--EEKSKMLARLLKSSHPEDLRAAN-----KLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATAGSIPGSTS--------ALLDLSGLD-----------LPPAGTTYPAMPTR---------PGEQASPEQPS------------ASVSLLDDELMSLGLSDPTPPS--GPSLDGTGWNSFQ----SSDATEP--------PAPALAQAPSMESRPPAQTSLP-----------ASSGLDDLDLLGKTLLQQSLP------PESQQVRWEKQQPTPRLTLRDLQNKSSSC------------SSPSSSATSLLHTVSPEPPRPPQQPVP---------TELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPL-------------------PGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NZ52-1", "uniprot_id": "GGA3_HUMAN", "id": "Q9NZ52-1", "name": "ADP-ribosylation factor-binding protein GGA3", "aln": "---------------MAEAEG-----ESLESWLNKATNPSNRQEDWEYIIGFCDQINKEL-EGPQIAVRLLAHKIQSP---QEWEALQALTVLEACMKNCGRRFHNEVGKFRFLN-ELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALP----EEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDD--EEKSKLLAKLLKSKNPDDLQEAN-----KLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQE-DSSDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEVATLTLPDSEGNSQCSNQGTLIDLAELD--TTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSN----ALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGS-PPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECP-------------------PGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQWGNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCV9-1", "uniprot_id": "A0A8M1NCV9_DANRE", "id": "A0A8M1NCV9-1", "name": "", "aln": "---------------MADPEG-----ESLESWLNKATNPSNRQEEWEYIIGFCDQINKEL-EGPQISVRLLAHKIQSP---QEWESLQALTVLEACMKNCGGRFHNEVGKFRFLN-ELIKLVSPKYLGDRVSERVKTKVIELLYNCSVALP----DEAKIAEAYHMLKKQGIVTKDPEVHVDRTLIPSP--KTKNPVFDN--EEKSKRLAELLKSKKPEDLQEAN-----RIIKNMVKEDEALQQKVSNRVSTLEKVNNSVKLLNEMLSHFKTD-ESTQEDKELLKDLYNDCDNLRTAVFRLATETEDDDSALGDILHASDDLSRVINSYKKIVEGQTIVIDVPASTPSGCINDRSSSE--ILIDLADLGSGTPSPLRHGLTPPQHSDSPAADLLTLTSLMGAQPSSSNTSSGSSSFQTSPPSSQLPSSLSLLDEELGSFGLGSLDSNS--RTSAEKTTKEAQSNQWISSQISNP---VTDFLCSSTPLNPPNSAAPPTSKTTSITDFEN-----SLQQSFKDLVLLDLDKTKSLS---NYSSLSSRELAAGKENIHP--ALNTLSLSAGIT---------PLPSAGSSAK---PQSFAPDSPVFRSLSPTLPSSQSSSGSDISLTSVFVPLEAIKPSKECPVTAYDKDGVRVLLHFATDHP-------------------TGRPDVLVIVVSMLNTAPLLVRNVMLQAAVPKSMRVKLQPPSGTEMAPFNPFMPPSSITQIMLLANPLKEKVRMRYKLTFILGDQPVTASGEIDQFPLVEKWCHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5E6-1", "uniprot_id": "GGA2_MOUSE", "id": "Q6P5E6-1", "name": "ADP-ribosylation factor-binding protein GGA2", "aln": "MAATAVAAGTGSPAGTESAEGGPGAAAALELWLNKATDPSMAEQDWSAIQKFCEQVNTDP-SGPTHAPWLLAHKIQSP---QEKEALYALTVLEICMNHCGEKFHSEVAKFRFLN-ELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFP----EDIKIRDAYQMLKKQGIIKQDPKLPMD-KILPPPSPWPKS-IFDAD-EEKSKLLTRLLKSNHPEDLQAAN-----RLIKNLVKEEQEKSEKVSRRVSAVEEVRSHVRVLREMLSMYRRP-GHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVRLYKQVVEGRVSAGNAVPAAVG-------------AIP--APR----------AFPNPEPCGLNCPLID--------LET----------------------PSLLHQDLAALGINDVPTRN---------------------QVVIP--------SCCNDKKQPGAITLMGGGIQSL---------------SADRNLLDLFSPQ----------PSPG-LNYVPQKSIPKEVPPGTKASPGWS-----------------------WEAGPLASSTASQNTP-------------LAHVFVPLESVKPSSLPPIVVYDRNGFRILLHFSQTGA-------------------PGHPDVKVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQTLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJY4-1", "uniprot_id": "GGA2_HUMAN", "id": "Q9UJY4-1", "name": "ADP-ribosylation factor-binding protein GGA2", "aln": "MAATAVAAAV---AGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDP-NGPTHAPWLLAHKIQSP---QEKEALYALTVLEMCMNHCGEKFHSEVAKFRFLN-ELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFP----EDIKIRDAYQMLKKQGIIKQDPKLPVD-KILPPPSPWPKSSIFDAD-EEKSKLLTRLLKSNHPEDLQAAN-----RLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRP-GQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLG-------------DIP--VSR----------VFQNPAGCMKTCPLID--------LEVDNGPAQMGT-----------VVPSLLHQDLAALGISDAPVTG---------------------MVSGQ--------NCCEEKRNPSSSTLPGGGVQNP---------------SADRNLLDLLSAQ----------PAPCPLNYVSQKSVPKEVPPGTKSSPGWS-----------------------WEAGPLAPSPSSQNTP-------------LAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGA-------------------PGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SRX1-1", "uniprot_id": "TM1L2_MOUSE", "id": "Q5SRX1-1", "name": "TOM1-like protein 2", "aln": "-------MEFL----LGNPFS-----TPVGQCLEKATDGSLQSEDWTLNMEICDIINETE-EGPKDAIRALKKRLSGN--RNYREVMLALTVLETCVKNCGHRFHLLVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSP----DLTGVVHIYEELKRRGIEFPMADLDALSPIHTPQRSVP--EMDPAA-TIPRSQTQPRTTAGTYSSPPPASYSTLQAPALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPG-QEDSSDLELLQELNRTCRAMQHRIVELISRVSNEE-VTEELLHVNDDLNNVFLRYERFERYRS------GRSVQ------------------------------------------------------------------------------NASNGVLSEVTEDNLIDLGPGS------------------------------------PAVVSPMVGSTAPPSSLSSQ---------------LAGLDLGTESVSGTLSS--------------LQQC-KPQDGFDMFAQTR--------------------------------GNSLAEQRKT------------------VTYEDPQAVGGLASALDNR-------KQNSEM---------------------IPVAQPSVMDDIEVWLRTDLKGDDLE-EGVTSEEFDKFLEERAKAAETVPDLPSP--PTEAP-APASNTSTRKKP--ERSDDALFAL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZP70-1", "uniprot_id": "A0A8I5ZP70_RAT", "id": "A0A8I5ZP70-1", "name": "", "aln": "-------MEFL----LGNPFS-----TPVGQCLEKATDGSLQSEDWTLNMEICDIINETE-EGPKDAIRALKKRLSGN--RNYREVMLALTVLETCVKNCGHRFHLLVANRDFIDSVLVRIISPKNNPPTIVQDKVLALIQAWADAFRSSP----DLTGVVHIYEELKRKGIEFPMADLDALSPIHTPQRSVP--EMDPAA-TIPRSQLQPRTTAGSYSSPPAAPYSTLQAPALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPG-QEDSSDLELLQELNRTCRAMQHRIVELISRVSNEE-VTEELLHVNDDLNNVFLRYERFERYRS------GRSVQ------------------------------------------------------------------------------NASNGVLSEVTEDNLIDLGPGS------------------------------------PAVVSPMVGSTAPPSSLSSQ---------------LAGLDLGTESVSGTLSS--------------LQQC-KPQDGFDMFAQTR--------------------------------GNSLAEQRKT------------------VTYEDPQAVGGLASALDNR-------KQSSEMRGRGGDSDLQPIDSWLMTQGMIPVAQPSVMDDIEVWLRTDLKGDDLE-EGVTSEEFDKFLEERAKAAETVPDLPSP--PTEAP-APASNTSNRKKP--ERSEDALFAL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZVM7-1", "uniprot_id": "TM1L2_HUMAN", "id": "Q6ZVM7-1", "name": "TOM1-like protein 2", "aln": "-------MEFL----LGNPFS-----TPVGQCLEKATDGSLQSEDWTLNMEICDIINETE-EGPKDAIRALKKRLNGN--RNYREVMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSP----DLTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVP--EVDPAA-TMPRSQSQQRTSAGSYSSPPPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEMLTEMVPG-QEDSSDLELLQELNRTCRAMQQRIVELISRVSNEE-VTEELLHVNDDLNNVFLRYERFERYRS------GRSVQ------------------------------------------------------------------------------NASNGVLNEVTEDNLIDLGPGS------------------------------------PAVVSPMVGNTAPPSSLSSQ---------------LAGLDLGTESVSGTLSS--------------LQQC-NPRDGFDMFAQTR--------------------------------GNSLAEQRKT------------------VTYEDPQAVGGLASALDNR-------KQSSEG---------------------IPVAQPSVMDDIEVWLRTDLKGDDLE-EGVTSEEFDKFLEERAKAAEMVPDLPSP--PMEAP-APASNPSGRKKP--ERSEDALFAL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88746-1", "uniprot_id": "TOM1_MOUSE", "id": "O88746-1", "name": "Target of Myb1 membrane trafficking protein", "aln": "-------MDFL----LGNPFS-----SPVGQRIEKATDGSLQSEDWALNMEICDIINETE-EGPKDAFRAVKKRIMGN--KNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSP----DLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETPSRQ-NSVSSNTSQRGDLSQHATPLPTP------AVLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPT-QVEPADLELLQELNRTCRAMQQRILELIPRISNEQ-LTEELLMINDNLNNVFLRHERFERFRT------GQTAK------------------------------------------------------------------------------ASSEAEL----ATDLIDMGP-----------------------------------------------DPAATNNLSSQ---------------LAGMNLGSRSVRAGLQS--------------LETSGHLEDDFDMFALTR--------------------------------GSSLADQRKG------------------VKYEAPQTTDGLAGALDAR-------QQSTGA---------------------IPATQARIMEDIEQWLSTDVGNSAEEPSGVTSEEFDKFLEERAKAADRLPNLASP--SAEGPPRPSPGTAPRRKTQ-EKDDDMLFAL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60784-1", "uniprot_id": "TOM1_HUMAN", "id": "O60784-1", "name": "Target of Myb1 membrane trafficking protein", "aln": "-------MDFL----LGNPFS-----SPVGQRIEKATDGSLQSEDWALNMEICDIINETE-EGPKDALRAVKKRIVGN--KNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSP----DLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQ-DSVGTDSSQQEDSGQHAAPLPAP------PILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPT-QAEPADLELLQELNRTCRAMQQRVLELIPQIANEQ-LTEELLIVNDNLNNVFLRHERFERFRT------GQTTK------------------------------------------------------------------------------APSEAEP----AADLIDMGP-----------------------------------------------DPAATGNLSSQ---------------LAGMNLGSSSVRAGLQS--------------LEASGRLEDEFDMFALTR--------------------------------GSSLADQRKE------------------VKYEAPQATDGLAGALDAR-------QQSTGA---------------------IPVTQACLMEDIEQWLSTDVGNDAEEPKGVTSEEFDKFLEERAKAADRLPNLSSP--SAEGPPGPPSGPAPRKKTQ-EKDDDMLFAL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSZ1-1", "uniprot_id": "Q9VSZ1_DROME", "id": "Q9VSZ1-1", "name": "TOM1-like protein 2", "aln": "------MASFFNVGALGNVFS-----TPVGQRIEAATDANLASENWAANMEICDMINESS-DTARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVKNCGKAFHVLVAQKDFIN-ELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQP----DLNGVTQMYMELKNKGIEFPANDLDAMAPIYTPQRSVP--EMPPQL-VAAQQHTISPQHMAAAAAAAAAA------AAPPSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLKPG-QESPDDYALLNELTSTCKEMQSRIVDLIGRVQDDE-LTAEFLRINDELNNVFLRHQRYEKNRSQGQGA-GVTSP------------------------------------------------------------------------------SAVLGAAMGLPGVGAAGAGATT------------------------------------VATLPPPPTTTAVSNTPQSD---------------QLLIDLIESSEEAQLPQSLGQISLGGGAPIGVQRSARPADEFDMLAQSRT------------------------------DGNHKSDLLRD------------------IPSVDAAAGSVTATASPYKPNQPQQAQRSAGE-----------------PPVVSKSTKENEIDEMEAWLGSSHIEGIEE---LTSSEFDKFLEERAAAAENLPTISASNSAASATTGSAGADSLRKTPKKPGAEEDLLAL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q923U0-1", "uniprot_id": "TM1L1_MOUSE", "id": "Q923U0-1", "name": "TOM1-like protein 1", "aln": "-------MAFG--KSHRDPYA-----TSVGHLIEKATFAGVLTEDWGQFLHICDIINTTQ-DGPKDAVKALKKRISKN--YNHKEIQLSLSLIDMCVQNCGPSFQSLIVKKEFIKDTLVKLLNPRYTLPLETQNRILNFIKTWSQGFPGGV----DVSEVKEVYLDLLKKGVQFPPSDGEPET-RQEAGQISP------------------NRPTSVPTAPALSS------IIAPKNPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPG-SENHEDIELLRKLYKTGREMQERIMDLLVVVENED-VTMELIQVNEDLNNAVLGYERFTRNQQRLLEQKRNRTE------------------------------------------------------------------------------ATRTSSEPSAPSCDLLDLSP----------------------------------------IVPVPTPNEGALNSVNAQ---------------LSGLSVSSLSPVITN-----------------NLYPSLQPQRDLLASEDI------------------------------EIPTLFPQRTS------------------QNLASSHTYDNF--HSNSV------------------------------------LLQPVSLHTATAAAAANQRLPPLPSSHPVLKDGDLQPPNYYEVMEFDPLAP----TTEAVYEEIDGYHQKEAQSHSDC------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LM81-1", "uniprot_id": "TM1L1_RAT", "id": "F1LM81-1", "name": "TOM1-like protein 1", "aln": "-------MAFG--KSHRDPYA-----TSLGHLIEKATFAGVQTEDWGQFMHICDIINTTQ-DGPKDAVKALKKRISKN--YNHKEIQLSLSLIDMCMQNCGPSFQSLIVKKEFVKDTLVKLLNPRYTLPLETQNRILSFIKMWSQGFPGGV----DVSEVKEVYLDLLKKGVQFPPLDGEPET-KQEAGQISP------------------SRPTSVPTAPALSS------IIAPKNPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPG-SENHEDIELLRKLYKTGREMQERIMDLLVVVENED-VTVELIQVNEDLNNAILGYERFTRNQQRLLEQKRNPTE------------------------------------------------------------------------------ANQTSSEPSAPSCDLLNLGP----------------------------------------VAPVPVSSEGPLNSVNAQ---------------LSGLNVSSQSPVITN-----------------NLYPSLQPQMDLLASEDT------------------------------EVPTLFPQRTS------------------QNLASSHTYDNFPDHSSSV------------------------------------LLQPVSLHTAPAAPSS-QRLPPLPSNHPVLKNSALQPPSYYEVMEFDPLAP----TTEAIYEEIDASHKKGAQSHSEC------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75674-1", "uniprot_id": "TM1L1_HUMAN", "id": "O75674-1", "name": "TOM1-like protein 1", "aln": "-------MAFG--KSHRDPYA-----TSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQ-DGPKDAVKALKKRISKN--YNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGV----DVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISS------------------NPPTSVPTAPALSS------VIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPG-SENHEDIELLQKLYKTGREMQERIMDLLVVVENED-VTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKE------------------------------------------------------------------------------ATNTTSEPSAPSQDLLDLSP----------------------------------------SPRMPRATLGELNTMNNQ---------------LSGLNFSLPSSDVTN-----------------NLKPSLHPQMNLLALENT------------------------------EIP-PFAQRTS------------------QNLTSSHAYDNFLEHSNSV------------------------------------FLQPVSLQTIAAAPSN-QSLPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAV--TTEAIYEEIDAHQHKGAQNDGD-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38817-1", "uniprot_id": "GGA2_YEAST", "id": "P38817-1", "name": "ADP-ribosylation factor-binding protein GGA2", "aln": "MSHPHSHSIYLSELPVRKPQALG---NPLLRKIQRACRMSLAEPDLALNLDIADYINEKQGAAPRDAAIALAKLINNR---ESHVAIFALSLLDVLVKNCGYPFHLQISRKEFLNELVKRFPGHPPLRYSKIQRLILTAIEEWYQTICKHSSYKNDMGYIRDMHRLLKYKGYAFPKISESDLAVLKPSNQLKTASEIQKEQEIAQAAKLEELIRRGKPEDLREAN--------KLMKIMAGFKEDNAVQAKQAISSELNKLKRKADLLNEMLESPDSQNWDNETTQELHSALKVAQPKFQKIIEEEQEDDALVQDLLKFNDTVNQLLEKFNLLKNGDSNAASQIHPSHVSAPLQ-------------------------------------------------------------------------QSSGALTNEINLIDFNDLDEAP---------------------------------SQGNNNTNGTGTPAAAETSVNDLLG------------DLTDLSISNPSTANQASFG-----LGGDIVLGSSQPAPPVTTTNNSNNTLDLLG-----------------------LSTPQSPTNSQAVNS------------SGFDLLMGFNPTTGTTTAPARTLVNQSPNLKIEFEISRE---------------------SNSVIRIKSFFTNLSSSPISNLVFLLAVPKSMSLKLQPQSSNFMIGNAKDGISQEGTIENAPANPSK-ALKVKWKVNYSVNSTQAEETAVFTLPNV-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: * : :.: :* . : : : : : :*:::: :: ** *: : *:. : : :: . : : : * :* : :: . :. :: . . : : . : ::: ::: .: :.. . .: . . . . . . : ", "identical_positions": 9, "similar_positions": 70, "identity": "1.15%" }, { "cls_id": "homologset.agr.SGD:S000001152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2R4-1", "uniprot_id": "TMD11_MOUSE", "id": "Q9D2R4-1", "name": "Transmembrane emp24 domain-containing protein 11", "aln": "---------------------MQIQTILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLESA-PGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMK---HLKDFFIAKKLV-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE21-1", "uniprot_id": "D3ZE21_RAT", "id": "D3ZE21-1", "name": "", "aln": "---------------------MQTQTILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKIQQWDIGRHDFLESA-PGLGMFVTVTN-NDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAVIVQAKDKVNEVAFTLRHLIEQIEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMK---HLKDFFIAKKLV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3V6N2-1", "uniprot_id": "G3V6N2_RAT", "id": "G3V6N2-1", "name": "", "aln": "MAG------VGVRP---LQGMVRFVLLVLTVCAAGARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPST-PGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRVRDLHLEAAVDLYTHCVCNVSAGPFSTQEDVG---VT---SLHSIVKNASV--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1V4-1", "uniprot_id": "TMED4_MOUSE", "id": "Q8R1V4-1", "name": "Transmembrane emp24 domain-containing protein 4", "aln": "MAG------VGVGP---LQGMVRFGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPST-PGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7H5-1", "uniprot_id": "TMED4_HUMAN", "id": "Q7Z7H5-1", "name": "Transmembrane emp24 domain-containing protein 4", "aln": "MAG------VGAGP---LRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPST-PGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1MZX1-1", "uniprot_id": "A0A8M1MZX1_DANRE", "id": "A0A8M1MZX1-1", "name": "", "aln": "---------MEMKT---LVSCVGFLLLFVWLSPS--QALYFHIGETEKKCFIEEIPDETMVIGRYRTQLWDKQAGSFLPST-PGLGMHVEIKDPETKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTVILIITGIWQMK---HLKSFFEAKKLV-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5I0E7-1", "uniprot_id": "TMED9_RAT", "id": "Q5I0E7-1", "name": "Transmembrane emp24 domain-containing protein 9", "aln": "MAAVRGVRVVGTSPGLLLGRGMRAFLLLLCLAARG-GALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPAT-PGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KF1-1", "uniprot_id": "TMED9_MOUSE", "id": "Q99KF1-1", "name": "Transmembrane emp24 domain-containing protein 9", "aln": "MAAVRGVRVVGSSPGLLLGRGMRAFLLLLWLAARG-SALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPAT-PGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVK6-1", "uniprot_id": "TMED9_HUMAN", "id": "Q9BVK6-1", "name": "Transmembrane emp24 domain-containing protein 9", "aln": "MAVELGVLLVRPRPGTGLGRVMRTLLLVLWLATRG-SALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPAT-PGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BA5-1", "uniprot_id": "Q86BA5_DROME", "id": "Q86BA5-1", "name": "", "aln": "-----------------MRDQFISLALILCVLHSA-CGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSS-PGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNST--AWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNLFHTCVYINEQCLCVCCLYIKKISALGLINDKINGLPDP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K5-1", "uniprot_id": "TMEDE_DROME", "id": "Q9I7K5-1", "name": "Transmembrane emp24 domain-containing protein eca", "aln": "-----------------MRDQFISLALILCVLHSA-CGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSS-PGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNST--AWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38819-1", "uniprot_id": "ERP5_YEAST", "id": "P38819-1", "name": "Protein ERP5", "aln": "-----------------MKYNIVHGICLLFAITQAVGAVHFYAKSGETKCFYEHLSRGNLLIG--DLDLYVEKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHTGDVTFTALDTGEHRFCFTPFYSK----KSATLRVFIELEIGN--VEALDSKKKEDMNSLKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLR---YLKNFFVKQKVV-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ..:*: . * :*: *.:. . : : : : . ..: : * : . :* : . * . **: .*:* :*: . : .. **:.:::.:*: : *:.:..: :* :::..* ***: * :: .:. : . : : : . : ", "identical_positions": 22, "similar_positions": 71, "identity": "8.3%" }, { "cls_id": "homologset.agr.SGD:S000001153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L1R3-1", "uniprot_id": "A0ABK0L1R3_RAT", "id": "A0ABK0L1R3-1", "name": "Adenylyltransferase and sulfurtransferase MOCS3", "aln": "MTNLREAPEADLRHLTRTVPNPGARGRLGFSTSQRVFRGILRFCDCFRSIVKASQAITHSFHFQALGSVLVFESLSDGKPETEVTPQMFPEDAVMAAPEDVAALQDEIARREEELASLKQRLAAALAVE--PEPERPIPVMP---LPSRAALSRDEILRYSRQLLLPELG-VRGQLRLAAASVLVVGCGGLGCPLAQYLAAAGVGRLGLVDHDVVETSNLARQVLHGEAQAGHAKAWSAAAALRRLNSAVEYVPYARALSEAWALDLVRGYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQMTVYHYDD-GPCYRCVFPRPPPAETVTNCADGGVLGVVPGVLGCVQALEVLKIAAGL--GTTYSGSMLLFDGL-GGHFRRIRLRRRRPDCVVCGQQPTVT------CLKNYEAFCGSSATDKCRSLKLLSPEERISVTDYKRLLDSG---VPHVLLDVRPQVEVDICRLQHSLHIPLSLLERRDADSLKLLGAALQEEKRNSQEGAALAVYVICKLGNDSQKAVRVLQSLTAVPELDSLKVQDISGGLMAWAAKIDGTFPQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BDX3-1", "uniprot_id": "MOCS3_MOUSE", "id": "A2BDX3-1", "name": "Adenylyltransferase and sulfurtransferase MOCS3", "aln": "----------------------------------------------------------------------------------------------MAAPEDVAALQAEITRREEELASLKRRLAAALTAE--PEPERPLRVPPP-PLAPRAALSRDEILRYSRQLLLPELG-VRGQLRLAAAAVLVVGCGGLGCPLAQYLAAAGVGRLGLVDHDVVETSNLARQVLHGEAQAGESKARSAAAALRRLNSAVECVAYPRALAEDWALDLVRGYDVVADCCDNVPTRYLVNDACVLAGRPLVSASALRFEGQMTVYHHDG-GPCYRCVFPRPPPPETVTNCADGGVLGAVPGVLGCAQALEVLKIAAGL--GSSYSGSMLLFDGL-GGHFRRIRLRRRRPDCVVCGQQPTVT------RLQDYEAFCGSSATDKCRALKLLCPEERISVTDYKRLLDSG---APHVLLDVRPQVEVDICRLPHSLHIPLSQLERRDADSLKLLGAALRKGKQESQEGVALPVYVICKLGNDSQKAVKVLQSLTAVPELDSLTVQDIVGGLMAWAAKIDGTFPQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95396-1", "uniprot_id": "MOCS3_HUMAN", "id": "O95396-1", "name": "Adenylyltransferase and sulfurtransferase MOCS3", "aln": "----------------------------------------------------------------------------------------------MASREEVLALQAEVAQREEELNSLKQKLASALLAEQEPQPERLVPVSP---LPPKAALSRDEILRYSRQLVLPELG-VHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDG-GPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGL--GPSYSGSLLLFDAL-RGHFRSIRLRSRRLDCAACGERPTVT------DLLDYEAFCGSSATDKCRSLQLLSPEERVSVTDYKRLLDSG---AFHLLLDVRPQVEVDICRLPHALHIPLKHLERRDAESLKLLKEAIWEEKQGTQEGAAVPIYVICKLGNDSQKAVKILQSLSAAQELDPLTVRDVVGGLMAWAAKIDGTFPQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AWD2-1", "uniprot_id": "MOCS3_DANRE", "id": "Q8AWD2-1", "name": "Adenylyltransferase and sulfurtransferase MOCS3", "aln": "------------------------------------------------------------------------------------------------MDDTIVSLKSQLLEREREVATLKKKLDQIEKGNS-TLPELQEKVTSLSPLRLNTSLNNDDIMRYSRQLLLPELG-VKGQIAISNISVLVVGCGGLGCPLAQYLAAAGIGRLGLLDYDVVELSNLHRQVLHTELTQGQPKALSAAQAISRMNSTVQCVPYHLQLSRENAIQLIQQYDIVADCSDNVPTRYLVNDACVLTSRPLVSASALRMEGQLTVYNYRG-GPCYRCLYPIPPPPETVTNCSDGGVLGVVPGIMGCLQALEVLKIASGQ--ECSFAQQLLMFDGE-QTRFRSIRLRSRQKECVVCGEKPTIT------ELQDYEHFCGSAATDKCRRLHLLSREQRVSVQDYKGILDHS---TPHLLLDVRPKVEVDICRLSNSLHIPLASLEDKKPEHITLLKEAISDLQEHLNNQSPVQVFVVCKLGNDSQKAVQLLEKMSGA-EVEAMTVKDIGGGLMAWAKKIDYCFPQY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLJ8-1", "uniprot_id": "MOCS3_DROME", "id": "Q9VLJ8-1", "name": "Adenylyltransferase and sulfurtransferase MOCS3", "aln": "------------------------------------------------------------------------------------MMESEVDSERTMLKREIAELRAALNQKEQCLRELDSLFSFATRPE--QEVVGNDLESPD--VAVHTKLTNDDIARYSRQLILPDFG-VQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIALLELNPHCEIQCHSRMLYPHNAMHIIRGYDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLTVYNYAN-GPCYRCIFPVPPPPEAVTNCGDGGVLGAVTGTIGAMQALEAIKVIVGM--GDVLAGRLLIFDGG-SGVFRNIRIRSKRPNCHMCSAQPLIT------ELINYEMFCGMHATDKNNPMLLLSTDERLSVEDYQQKIQA----QPHLLIDVRPTAEFEICQLPEAVNVPLVEILDDS--YLKRLGKQLEDKE--------LPIVLVCRRGNDSQIAVQHLRN-----RFPTHFVRDLIGGLHAWTNSVDPSFPIY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38820-1", "uniprot_id": "UBA4_YEAST", "id": "P38820-1", "name": "Adenylyltransferase and sulfurtransferase UBA4", "aln": "-----------------------------------------------------------------------------------------------MNDYHLEDTTSELEALRLENAQLREQLAKREDSS------------------RDYPLSLEEYQRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKGYNYILDCTDSPLTRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPPPPNAVTSCQEGGVIGPCIGLVGTMMAVETLKLILGIYTNENFSPFLMLYSGFPQQSLRTFKMRGRQEKCLCCGKNRTITKEAIEKGEINYELFCGARNYNVCE------PDERISVDAFQRIYKDDEFLAKHIFLDVRPSHHYEISHFPEAVNIPIKNLRDMNG-DLKKLQEKLPSVEKDSN------IVILCRYGNDSQLATRLLKD-----KFGFSNVRDVRGGYFKYIDDIDQTIPKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * : . *. :: **.**::: : * * **: : **:** ****** ***.** *::*::* * ** **: **:** . * *. ** : .:*. : : * *:.:.: *: : ** *. ****:.*..* . .:**.*.* :**:*: :. . ******.:* ***.::**.* :***:* * :* *:*.:*: * : ::::.. :* :::* :: .* *. . :* :** *** : . ::*:** :: . *:::**** . :*.:: .::::*: : . :. * : . : : ::*: ***** *.: *.. .. *:*: ** : .:* :* *", "identical_positions": 120, "similar_positions": 130, "identity": "21.02%" }, { "cls_id": "homologset.agr.SGD:S000001155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A8L3-1", "uniprot_id": "A0A8I6A8L3_RAT", "id": "A0A8I6A8L3-1", "name": "Aspartyl aminopeptidase", "aln": "-----MNPPEAEVAMNGRARKEAIQATARELIKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWD--ILPENKYFLTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRRSQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRFVHIERPILRIPHLAIHLQRNVNENFGPNTEMHLVPIL-----ATAVQEELEKGTPEPGPLSATDERHHSVLMSLLCTHLGLS-PDNIMEMELCLADTQPATLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLAREPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRISAS---------PQRLTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESLIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2W0-1", "uniprot_id": "DNPEP_MOUSE", "id": "Q9Z2W0-1", "name": "Aspartyl aminopeptidase", "aln": "------------MAMNGRARKEAIQATARELLKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWD--IVPENKYFLTRNSSSIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRRSQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRLVHIERPILRIPHLAIHLQRNINENFGPNTEIHLVPIL-----ATAVQEELEKGTPEPGPLGATDERHHSVLMSLLCTHLGLS-PDSIMEMELCLADTQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLARDPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRISAS---------PQRLTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESMIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULA0-1", "uniprot_id": "DNPEP_HUMAN", "id": "Q9ULA0-1", "name": "Aspartyl aminopeptidase", "aln": "MSGHSPTRGAMQVAMNGKARKEAVQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELKETEKWN--IKPESKYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRSRRSQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVHVERPILRIPHLAIHLQRNINENFGPNTEMHLVPIL-----ATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCAHLGLS-PKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYDNEEVGSESAQGAQSLLTELVLRRISAS---------CQHPTAFEEAIPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNLLVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38821-1", "uniprot_id": "DNPEP_YEAST", "id": "P38821-1", "name": "Aspartyl aminopeptidase 4", "aln": "---------MFRIQLRTMSSKTCKSDYPKEFVSFLNSSHSPYHTVHNIKKHLVSNGFKELSERDSWAGHVAQKGKYFVTRNGSSIIAFAVGGKWEPGNPIAITGAHTDSPALRIKPISKRVSEKYLQVGVETYGGAIWHSWFDKDLGVAGRVFVKDAKTGKSIARLVDLNRPLLKIPTLAIHLDRDVNQKFEFNRETQLLPIGGLQEDKTEAKTEKEINNGEFTSIKTIVQRHHAELLGLIAKELAIDTIEDIEDFELILYDHNASTLGGFNDEFVFSGRLDNLTSCFTSMHGLT--LAADTEIDRESGIRLMACFDHEEIGSSSAQGADSNFLPNILERLSILKGDGSDQTKPLFHSAILETSAKSFFLSSDVAHAVHPNYANKYESQHKPLLGGGPVIKINANQRYMTNSPGLVLVKRLAEAAKVPLQLFVVANDSPCGSTIGPILASKTGIRTLDLGNPVLSMHSIRETGGSADLEFQIKLFKEFFERYTSIESEIVV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : * . . .:*::.*:* * **:*.* : :.:*:. ** **.* : * : :.***:***.*:********:: *** ::: *******.**:* *:* . : *********.** :***:** :****::* ..:*: ::*.::**:*:** *****:*::*::* * * :*:** * : * * .. * .: : :***: *:.*:. .*.:. ..* ::** * * :.:.*** :**:*: ***** *** :::.* *. .: :. :*::: :*:**:**.*****:* : :*.*:* :*: *: .***::*:*:******** :*:*.:*:**: *****:*::*** :*: . :::.:* . **** ::* **:***:********: *:*.****.* *:****** . ::.: :.*** *** :.*:. :::* ", "identical_positions": 204, "similar_positions": 160, "identity": "40.64%" }, { "cls_id": "homologset.agr.SGD:S000001156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K012-1", "uniprot_id": "FBP1L_MOUSE", "id": "Q8K012-1", "name": "Formin-binding protein 1-like", "aln": "----------------------------------------------------------------MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEE-------------PRFTSCIAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEK-----AKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISAAKQESGKMDSKSTVGKAKGKLWLFGKK--------PKPQSPPLTPTSLFTSSTPNGSQFLTLSIEPVHYCMNEIKTGKPRIPSFRSLKRGVSLIMGPALEDFSHLPPEQRR---KKLQQRIDELNRGLQK---EADQKEALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGIR---GDRRHS--------SDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHSEFDDEFEDDDPLP--------------------------------------AIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNG----EEGYVPTTYIDVTLEKSSKGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2HWF0-1", "uniprot_id": "FBP1L_RAT", "id": "Q2HWF0-1", "name": "Formin-binding protein 1-like", "aln": "----------------------------------------------------------------MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEE-------------PRFTSCIAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEK-----AKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTVSDGTISASKQEGGKMDSKSTAGKAKGKLWLFGKK--------PKPQSPPLTPTSLFTSSPPNGSQFLTLSIEPVHYCMNEIKTGKPRIPSFRSLKRGWSMKMGPALEDFSHLPPEQRR---KKLQQRIDELNRGLQK---ESDQKEALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGVR---GDRRHS--------SDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHSEFDDEFEDDDPLP--------------------------------------AIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNG----EEGYVPTTYIDVTLEKNSKGS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T0N5-1", "uniprot_id": "FBP1L_HUMAN", "id": "Q5T0N5-1", "name": "Formin-binding protein 1-like", "aln": "----------------------------------------------------------------MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEE-------------PRFTSCVAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEK-----AKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKK--------PKPQSPPLTPTSLFTSSTPNGSQFLTFSIEPVHYCMNEIKTGKPRIPSFRSLKRGWSVKMGPALEDFSHLPPEQRR---KKLQQRIDELNRELQK---ESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGR---GDRRHS--------SDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLP--------------------------------------AIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNG----EEGYVPTSYIDVTLEKNSKGS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80TY0-1", "uniprot_id": "FNBP1_MOUSE", "id": "Q80TY0-1", "name": "Formin-binding protein 1", "aln": "----------------------------------------------------------------MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEE------------YKYTACKAFLSTLNEMNDYAGQHEVISENMTSQITVDLMRYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEK-----ARQQAQIRQQMAEDSKADYSLILQRFNQEQWEYYHTHIPNIFQKIQEMEERRIVRIGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVVEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSSSK-EGKPE--LRFGGKSRGKLWPFIKKNKLMSLLTSPHQPPPPPPASASPSAVPNGPQSPKQPKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGVTPEDFSNFPPEQRR---KKLQQKVDDLNREIQK---ETDQRDAITKMKDVYLKNPQMGDPASLDQKLTEVTQNIEKLRLEAQKFEAWLAEVEGRLPAR-SEQARRQSGLYDGQ-THQTVTNCAQDRESPDGSYTEEQSQE----SEHKVLAPDFDDEFDDEEPLP--------------------------------------AIGTCKALYTFEGQNEGTISVVEGETLSVIEEDKGDGWTRIRRNED----EEGYVPTSYVEVYLDKNAKGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R511-1", "uniprot_id": "FNBP1_RAT", "id": "Q8R511-1", "name": "Formin-binding protein 1", "aln": "----------------------------------------------------------------MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEE------------YKYTACKAFLSTLNELNDYAGQHEVISENMTSQITVDLVRYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEK-----ARQQAQMRQQMAEDSKADYSLILQRFNQEQWEYYHTHIPNIFQKIQEMEERRIVRIGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVVEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSSSK-EGKPE--LKFGGKSRGKLWPFIKKNKLMTLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGVTPEDFSNFPPEQRR---KKLQQKVDDLNKEIQK---ETDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVTQNIEKLRLEAHKFEAWLAEVEGRLPAR-SEQARRQSGLYDGQ-THQTVTNCAQDRESPDGSYTEEQSQE----SEHKVLATDFDDEFDDEEPLP--------------------------------------AIGTCKALYTFEGQNEGTISVVEGETLSVIEEDKGDGWTRIRRNED----EEGYVPTSYVEVYLDKNAKGS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RU3-1", "uniprot_id": "FNBP1_HUMAN", "id": "Q96RU3-1", "name": "Formin-binding protein 1", "aln": "----------------------------------------------------------------MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEE------------YKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEK-----ARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSNSRGEGKPD--LKFGGKSKGKLWPFIKKNKLMSLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGATPEDFSNLPPEQRR---KKLQQKVDELNKEIQK---EMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVSQNIEKLRVETQKFEAWLAEVEGRLPAR-SEQARRQSGLYDSQ-NPPTVNNCAQDRESPDGSYTEEQSQE----SEMKVLATDFDDEFDDEEPLP--------------------------------------AIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNED----EEGYVPTSYVEVCLDKNAKDS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4Q2-1", "uniprot_id": "A0A8M3B4Q2_DANRE", "id": "A0A8M3B4Q2-1", "name": "", "aln": "-----------------------------------------------MHSNRGLSRRSCLETMSCSWGTELWDQFDNLEKHTQWGIEFLERYTKFVKERSEIELSYAKQIRNLSKKYQLKKNSKEEEE------------YKYTTCRAFLMTLNELNDYAGQHEVIAENLSSQIIAELSRYTQELKAERKSHFHDGRRAQQHIENSWKQLESSKRRFERDCKEADRAQHYFDKMDADINVTKADVEKRCSLKAKQQAQMRHQIAEDSKNEYLTYLQKFNKDQHEHYYTLIPHIFQRIQEMEERRVGRVRESMRVYTEVERKVLPIVSKCLDGMTKAAESVEPKMDSKQVVESYKSGFEPPGDVDFEDYSVSMKRAVSESSFLNARGESRR--------RSRSKLWPLLKRNKLMSLLASPRQPPPPPPTSPSPDGLQNGPQSPQQPKEPLSQRLNDFMGTKHKMHCLRSLKRGLSLKLGTGQEDYSHLPPEQRR---KKLQAKLNDVNKDIQK---EMDQRDALTKMKDVYIKNPHLGDPDSIDPRLEEITQSLEKLQFEAHKYEGWLTEVERKLLEKGSESQRRQSSHFDSQGNTPLTNNYGQNRESPDGSYTEDPSTEN--TMQFKSRSTEFDDEFDEEEPLP--------------------------------------TIGTCKALYPFEGQNEGTISMAEGEMLYVIEEDKGDGWTRVRRNED----EEGYVPTSYIKLFLDTNAKGAMTYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CJ53-1", "uniprot_id": "CIP4_MOUSE", "id": "Q8CJ53-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERAEVEQAYAKQLRSLVKKYLPKRPTKDDPE------------VKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEK-----AKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSQVLIELHKSGFARPGDLEFEDFSQVINRVPSDSSLGTP--DGRPE-LRAASSRSRAKRWPFGKKNKP-------RPPSLSLLGGHLPSTLSDGPSSPRSGRDPLAILSEISKSVKPRLASFRSFRG---GRGTVATEDFSHLPPEQQR---KRLQQQLEERNRELQK---EEDQREALKKMKDVYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPP-TTAPPDSSSSSTNSGSQDNKESSSEEPPSEGQDTPIYTEFDEDF--EEPAS--------------------------------------PIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQG----AEGYVPTSYLRVTLN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97531-1", "uniprot_id": "CIP4_RAT", "id": "P97531-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERVEVEQSYAKQLRSLVKKYLPKRPAKDDPE------------IKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEK-----AKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSKVLIELHKSGFARPGDLEFEDFSQVMNRVPSDSSLGTP--DGRPE-LRAASSRSRAKRWPFGKKNK------------------------------------------------------------------TVVTEDFSHLPPEQQR---KRLQQQLEERNRELQK---EEDQREALKKMKDVYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHTRPPDPP-TTAPPDSSSSSNNSGSQDNKESSEEPPSEEGQDTPIYTEFDEDF--EEPAS--------------------------------------PIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQG----GEGYVPTSYLRVTLN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15642-1", "uniprot_id": "CIP4_HUMAN", "id": "Q15642-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPE------------SKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEK-----AKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPS-DGRPE-LRGPG-RSRTKRWPFGKKNKP-------RPPPLSPLGGPVPSALPNGPPSPRSGRDPLAILSEISKSVKPRLASFRSLRG---SRGTVVTEDFSHLPPEQQR---KRLQQQLEERSRELQK---EVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPP-ASAPPDSSS---NSASQDTKESSEEPPSEESQDTPIYTEFDEDFE-EEPTS--------------------------------------PIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEG----GEGYVPTSYLRVTLN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3Q6-1", "uniprot_id": "CIP4_DANRE", "id": "Q5U3Q6-1", "name": "Cdc42-interacting protein 4 homolog", "aln": "----------------------------------------------------------------MDWGTELWDQYDILDKHTQSGLDLVDKYMKFVKERTDIEQNYAKQLRNLTKKYSPKRGSKEEQE------------CRFSNHQAFLDILNEMNDYAGQRELIAENMMINICVELNKYLQELKQERKMHLSEAKKSQQSLEAMYKQLDNSKKRFEREWREAEKAAQYADKTDQDLNATKADVEK-----AKQQAHLRTHIAEDCKNDYAAQLQKYNKGQSQFYFTDMPQIFNKLQDMDERRIKKMAQGYILFADTERHVMPIIGKCLEGMTRAGTNVNARNDSMVLIEQHKSGFERPGDLDFEDYSQGINRASSDSSLGTP--KGPLE-LLGKN-KNKTFRL-FNKKSKF-------TPEK------------------------------------------------------PVDTEGFTHLPPEQRR---KRLQQKIDDMSKELQK---EMDQSEALGKMKDVYEKNPQMGDPASLAPQIGQTAQNMDRLRGELNKYESWLAEAGG-----RGDSIRYSTHSINNN-GAHNPNSHDGSCTLFSPG-ALSDETDPSQ-----AIYTEFDDEFEEEELAT--------------------------------------PIGQCTALYNFPGSSEGTISMQEGEVLAVVEEDKGDGWTRVRRNNG----DEGYIPTSYATITLNK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNK4-1", "uniprot_id": "A8JNK4_DROME", "id": "A8JNK4-1", "name": "", "aln": "MLKKKLAQITKKKTVADLEAECVHSAIAFTCVRVCAKLLASGSSRSSSNNKLAESENSAQNSNNMSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK--KEEED------------NEFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQLSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVER-----YKNVMTSKIQQSDDAKNEYANQLQKTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESINEKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGTMSANKLKKRVGIFNIFGSN-----------------------------------------------------------KNSLTADGQKEDFSDLPPNQRR---KKLQAKIAELTQNIAQ---ETKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIEITLYA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38822-1", "uniprot_id": "BZZ1_YEAST", "id": "P38822-1", "name": "Protein BZZ1", "aln": "------------------------------------------------------------MSADLSIGNEIKDSFKETHKWVQNNLKWLKDIEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAWNEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELEKAKKDYDEACSTMEMARNRYTKASNDRNKKKLDEKE--------------MEMNKCKNEYLIKINQANRTKDKYYFQDVPEVLDLLQDVNEAKTLFLNDLWLKAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVWHDDEKFAVPSSLEVEDLRIKLAKAENDYNSLQDKTQNELSKLS----TLNKIKHEMKTNEDNINATKFYDTLKEYLNVVSPFTSHETLKLQAEVQIESIQNNVPEEYDLSTDNIDLSKTKKKSGIFSKFKHNILNVDSKPSSGGSTGNGNGGPLHITSLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNSSDDGKNKVLYAYVQKDDDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAATVKANDRGPAPEVP----------------------------PPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYG-ECDG----LKGLFPTSYCK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*: *. . .: .:. :. :* ::* :* *: :: * :* *: .. . : :: *.: . : ::: :: .: .: : : . : .:: :*: ::. : * . : . * * .: : :. :. * :* ::. * : ..: :* : . :*:::* : . :. : : . :.: ::. . . :: .:. ..: * *. :: . . :. .::: .::: .: : . . . ::. :: . : : . : :. : . . . .: *:* : . .:. :.: *: : ::. *.*.*** . :. :* .**:* ", "identical_positions": 35, "similar_positions": 162, "identity": "4.62%" }, { "cls_id": "homologset.agr.SGD:S000001157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76064-1", "uniprot_id": "RNF8_HUMAN", "id": "O76064-1", "name": "E3 ubiquitin-protein ligase RNF8", "aln": "MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKR---KIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38823-1", "uniprot_id": "DMA1_YEAST", "id": "P38823-1", "name": "E3 ubiquitin-protein ligase DMA1", "aln": "--MSTNTVPSSPPNQTPPAASGIATSHDHTKFNNPIRLPISISLTINDTPNNNSNNNSVSNGLGILPSRTATSLVVANNGSANG----------------------NVGATAAAAATVETNTAPAVNTTKSIRHFIYPPNQ---------VNQTEFSLDIHLPPNTSLPERIDQSTLKRRMDKHGLFSIRLTPFIDTSSTSVANQGLFFDPIIRTAGAGSQIIIGRYTERVREAISKIPDQYHP------------VVFKSKVISRTHGCFKVDDQGN--------WFLKDVKSSSGTFLNHQRLSSASTTSKDYLLHDGDIIQLGMDFRGG----TEEIYRCVKMKIELNKSWKLKANAFNKEALSRIKNLQKLTTGLE-----QEDCSICLNKIKP-------CQAIFISP----CAHSWHFHCVRRLVIMNYPQFMCPNCRTNCDLETTLESESESEFENEDEDEPDIEMDIDMEINNNLGVRLVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *... .. . . :. * . ::: .:.:. .: :. .: :*.. :* ... . .: :* * ** ::*.. ..* : : : ::* : * *: .: :**** *.:. *..:... * :. .. : . : ::.:. : * :*:** : : ** :* :. .. : : :* :: .: .. ::*..* : : ::::. .. : .* ..* . . : ::: : *::: * .::: :.:: : * :. : . : *: :: *:*:: . * :*: :*.: *. **.. ****: :*:.. : :: ** **.: . :* .:. : :: ..::: : *.:. . **. ", "identical_positions": 57, "similar_positions": 177, "identity": "11.66%" }, { "cls_id": "homologset.agr.SGD:S000001158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LBZ4-1", "uniprot_id": "A0ABK0LBZ4_RAT", "id": "A0ABK0LBZ4-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 7", "aln": "--------------------------------------------------MPMVTRRLRDPDINPCLSESD--ASTRCMDEN--------NYDRERCSSYFLKYKNCRRF-WNSVMIQRRQNG-VQPSMPTAAE-RDEILGAMQK-MPY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2Q5-1", "uniprot_id": "CHCH7_MOUSE", "id": "Q8K2Q5-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 7", "aln": "--------------------------------------------------MPMVTRRLRDPDINPCLSESD--ASTRCMDEN--------NYDRERCSSYFLKYKNCRRF-WNSVMIQRRQNG-VQPSMPTAAE-RDEILGAMQK-MPY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUK0-1", "uniprot_id": "CHCH7_HUMAN", "id": "Q9BUK0-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 7", "aln": "--------------------------------------------------MPSVTQRLRDPDINPCLSESD--ASTRCLDEN--------NYDRERCSTYFLRYKNCRRF-WNSIVMQRRKNG-VKPFMPTAAE-RDEILRAVGN-MPY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPC2-1", "uniprot_id": "Q9VPC2_DROME", "id": "Q9VPC2-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 7", "aln": "--------------------------------------------------MPRNQNAEQD---NPCLKEQE--LSFKCLNKN--------NFDRDKCEIYFANYNNCKEF-WNKVKTERRAKG-IAPYLPPLEE-RDGIKAEYMKGKPQQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38824-1", "uniprot_id": "COX23_YEAST", "id": "P38824-1", "name": "Cytochrome c oxidase-assembly factor COX23, mitochondrial", "aln": "MEKPSPTRRQTSSLSTISNGMTMTNDNRDTTNTNSGSTSSNNSQPSSSSTPPAASGPVTDRTKVNYVPKSDDPSSFQYYPDDPENPVNKYKFALKADSQYYDPCEESSKLSFQCLERNDYDRSKCQEYFDAYRECKKQWLTARRKNRQQWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :.: * : .: :: . . *: ::. .: :: : : .. : . * :. : ", "identical_positions": 5, "similar_positions": 28, "identity": "3.31%" }, { "cls_id": "homologset.agr.SGD:S000001159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZW5-1", "uniprot_id": "TOM70_MOUSE", "id": "Q9CZW5-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPIEAAMAAAAAPGSGNGVGGGGGTAGPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGG---------RGDASGLKRNSERKTPEGRASPALGSGHHDGSGDS--LEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNRE----PLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALE---VKENSGYLKAKQYMEE--ENYDKIISECSKEID---AQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG-------LLQLQWKQD--------LDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q75Q39-1", "uniprot_id": "TOM70_RAT", "id": "Q75Q39-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGG---------RGDASGLKRNSERKTPEGRASPALGSGP-DGSGDS--LEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNRE----PLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALE---VKENSGYLKAKQYMEE--ENYDKIISECSKEID---AQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG-------LLQLQWKQD--------LDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94826-1", "uniprot_id": "TOM70_HUMAN", "id": "O94826-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPVEAAVVAAAVPSSGSGVGG-GGTAGPGTGG--LPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARG---------RGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAH--LDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNRE----PLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALE---VKENSGYLKAKQYMEE--ENYDKIISECSKEID---AEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG-------LLQLQWKQD--------LDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC8-1", "uniprot_id": "Q9VKC8_DROME", "id": "Q9VKC8-1", "name": "", "aln": "----------MAMTLNIGSMK-----------------LTKWQLALILGTPLAIGLGTYAVKSWTAASKELDG---------EKKRPKAKIEKQAISLDGTAPDQELERNQKSAELG--EKLSPLKEANNYKTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRV----PVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPP---------------KGFLRAHLAFLE--EKYEEIIPACTEEIESSEAEAQYKVEALLMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQA-------IMVLQWRGD--------INLAVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSGLMAQGVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38825-1", "uniprot_id": "TOM71_YEAST", "id": "P38825-1", "name": "Protein TOM71", "aln": "-MAENSLLRFITKNKVAILATVSAGTAAVGAYVYYQQIKQQQQQQLKGTKDNRRQSEAFAGQNEDEADLKDDGSVVSGSNKRKKKKNKRKRNNKAKSGEGFDYPSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNEP-----VFYSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSLASFFGIFDSHLEVSSVNTSSNYDTAYALLSDALQRLYSATDEGYLVANDLLTKSTDMYHSLLSANTVDDP----LRENAALALCYTGIFHFLKNNLLDAQ-----VLLQESINLHPTPNSYIFLALTLADKENSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYIQLACLLYKQG-------KFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKATILARQSSQDPTQLDEEKFNAAIKLLTKACELDPRSEQAKIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFAEAAKIQKRLRADPIISAKMELTLARYRAKGML--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : * : . : * . . * :.: : :* . . . . * *..**: : ::::**: * **. *.* **.* :*.: . .:* : * ::*::* : ** *** *:* : .:.: *::. .: *:. . : :: *: . :: : ::** : :: * . . : * .*:* *: : : : *..::. : : : . ** . *::* .. :: :: . : : . : * . : :: * * ::* . .*::*.*: ::*: : * :*: . : *: . . * . *: . :. *:: :** * :: *: *:*: :* * : *. . * : * . :: * * :: .::*:.** *:* :.: * :. :::* :: .*:::*:.: *:: * : :: :** * .: . :. ", "identical_positions": 86, "similar_positions": 182, "identity": "12.97%" }, { "cls_id": "homologset.agr.SGD:S000001161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFT2-1", "uniprot_id": "SET1B_MOUSE", "id": "Q8CFT2-1", "name": "Histone-lysine N-methyltransferase SETD1B", "aln": "--------------------------MENSHP-HHHHQQPPPQPG---------PSGERRNHHWRSYKLMID----PALKKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNVRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKEAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVG--ELDAISP-IVSETLQLSDALKRLKDGSLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTP-NSYG-------------QGTPITPR-LGTPFSQDSSYSSRQ----------------PTPSYLFS-QDPTATFKARRHES-----KFTDAYNR----------------------------------------------------------RHEHHYVHN----SAVAGATAPFRGSSDLSFGTVGSSG----TPFKAQSQDAT--------------------TFAHTPPPAQTATASGFKSAFSP----------YQTPAPPFPPPPE----------EPTATAAFG---------------------------------------SRDSGEFR----RAP-APPPLPPAEPP--------AKEKPGTPPGPPPPDSNSMELGGR-------------------------------------------PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLPFLREQ-DSDTEIQMEGSP-----------ISSSSSQLSPLSHFGTNSQPGFRG-------PSPPSSRPSSTGLEDISPTPLPDSDEDEDLGLGLGPRPPPEPGPPDPMGLLGQTAEVDLDLAGDRTPTSERMDEGQQSSGEDMEISDDE-----MPSAPITSADCPKPMVVTPGAGAVAAPNVLAPNLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPP-AHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQMLSRLMTGQG----ACPYPPFMAAAAAAASAGLQFVN-LPPYRSPFSLSNSGPGRGQ-----------HWPP-------------------LPKFDPSVPP-------------------PGYIPRQED------------PHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVK-----SGEHKDEDRPKPKDRIAS------CLLESWGK-GEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTASSGDQKRLRPSTSVDEEDEESERERDRDIADAPCELTK---RDPKSVGVRRRPGRPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEDRESTEEEEEEEEEEAEEEEEEGPRSRISSPSSSSSSDKDDEDDNEADSDGQI------DSDIDDQGAPLSEASEKDNGDSEEEETESITTSKAPAESSSSSS-----ESSGSSEFESSSESESSSSSSEDEEEMTVPGVEEEEEEEEEEEKETAMAAATVVAMAEESMPPAGGQDFEQDRAEVPLGPRGPMRESLGTEEEVDIEAEDEVPEMQAPELEEPPLPMGARKLEGSPEPPEEPGPNTQGDMLLSPELPARETEEAQLPSPPEHGPESDLDMEPEPPPMLSLP-LQPPLPPPRLLRPPSPPPEPETPEPPKPPVPLEPPPEDHPPRTPG-----LCGSLAKSQSTETVPATPGGEPPLSGSSSGLSLSSPQVPGSPFSYPSPSPGLSSGGLPRTPGRDFSFTPTFPEPSGPLLLPVCPLPTGRRDERTGPLASPVLLETGLPLPLPLPLPLPLALPVPVLRAQPRPPPQLPPLLPATLAPCPTPIK-RKPGRPRRSPPSMLSLDGPLVRPPPGPALGRDLLLLPGQPPAPIFPSAHDPRAVTLDFRNTGIPAPPPPLPPQPPPPPPPPPVESTKLPFKELDNQWPSEAIPPGPR-RDEVTEEYVDLAKVRGPWRRPPKKR---HEDLVAPSASPEPSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAK---KKKREDGI-REHVTGCARSEGFYTIDKKDKLRYLNSSR--ASTDEPPMDTQG-------MSIPAQPHASTRAGSERRSEQRRLLSSFTG--SCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIE---DVKIPCLCGSENCRGTLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ANV4-1", "uniprot_id": "A0A8I6ANV4_RAT", "id": "A0A8I6ANV4-1", "name": "[histone H3]-lysine(4) N-methyltransferase", "aln": "--------------------------MENSHP-HHHHQQPPPQPG---------PSGERRNHHWRSYKLMID----PALKKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKEAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVG--ELDAISP-IVSETLQLSDALKRLKDGNLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTP-NSYG-------------QGTPITPR-LGTPFSQDSSYSSRQ----------------PTPSYLFS-QDPAATFKARRHES-----KFTDAYNR----------------------------------------------------------RHEHHYVHNSAVAAAVAGATAPFRGSSDLSFGTVGGSGG--GTPFKTQSQDST--------------------TYAHTPPPAQTATASGFKSAFSP----------YQTPAPPFPPPPE----------EPTATAAFG---------------------------------------TRDSGEFR----RAP-APPPLPPSEPP--------AKEKPGTPPGPPPPDNNSMELGGR-------------------------------------------PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLPFLREQ-DSDTEIQMEGSP-----------ISSSSSQLSPLTHFGTNSQPGFRG-------PSPPSSRPSSTGLEDISPTPLPDSDEDDDLGLGLGPRPPPEPGPPDPMGLLGQTAEVNLDLAGDRTPTSERMDEGQQSSGEDMEISDDE-----MPSAPITSADCPKPMVVTPGAGAVAAPNVLAPNLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQMLSRLMTGQG----TCPYPPFMAAAAAAASAGLQFVN-LPPYRSPFSLSNSGPGRGQ-----------HWPP-------------------LPKFDPSVPP-------------------PGYIPRQED------------PHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVK-----SGEHKDEDRPKPKDRIAS------CLLESWGK-GEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTASSGDQKRLRPSTSVDEEDEESERERDRDMADAPCELAK---RDPKSVGVRRRPGRPLELDSGGEEDEKESLSVSSSSSASSSSGSSTTSPSSSASDKEEEERESTEEEEEEEEAEEEEEDEERPRSHISSPSSSSSSDKDDDDDD--DSDDQI------DSDIDDQGTALSVASEKDNVDSEEEEIERVTTSKAPAVSSSSSSSSSSSESSGSSEFDSSSESSSSSSSSEDEDEMTVPG-EDEEEEEEEEEKETAMATATVVAMAEESMPPVGGQDFEQDRAEVPLGPRGPLRESLCTEEEVDIEAEDEVPEMQAPVPEESPLPMGAQELS--PEPPEEPSPNTQGDMLLSPELPARET-EAQPPSLPEHGPESDLEVEPEPPPMLSLP-LQPPLLPPRHPRPPSPPPEPETPEPPKPPVPLEPPPEDQPPRTPG-----LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPSPSPGLSSGGLPRTPGRDFTFTPTFPEPSGPLLLPVCPLPTGRRDERAGPLASPVLLETGLPLPLPLPLPLPLALPVPVLRAQPRPPPQLPPLLPATLAPCPTPIK-RKPGRPRRSPPSMLSLDGPLVRPPPGPALGRDLLLLPGQPQAPIFPSAHDPRAVTLDFRNTGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR-RDEVTEEYMDLAKVRGPWRRPPKKR---HEDLVAQSASPEPSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAK---KKKREDGI-REHVTGCARSEGFYTIDKKDKLRYLNSSR--ASTDEPPMDTQQG------MSIPAQPHASTRAGSERRSEQRRLLSSFTG--SCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIE---DVKIPCLCGSENCRGTLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPS6-1", "uniprot_id": "SET1B_HUMAN", "id": "Q9UPS6-1", "name": "Histone-lysine N-methyltransferase SETD1B", "aln": "--------------------------MENSHPPHHHHQQPPPQPG---------PSGERRNHHWRSYKLMID----PALKKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVG--ELDAVSP-IVNETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTP-NSYG-------------QGTPLTPR-LGTPFSQDSSYSSRQ----------------PTPSYLFS-QDPAVTFKARRHES-----KFTDAYNR----------------------------------------------------------RHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSA--------------------TFAHTPPPAQATPAPGFKSAFSP----------YQTPVAHFPPPPE----------EPTATAAFG---------------------------------------ARDSGEFR----RAP-APPPLPPAEPL--------AKEKPGTPPGPPPPDTNSMELGGR-------------------------------------------PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREP-DSDTELQMEGSP-----------ISSSSSQLSPLAPFGTNSQPGFRG-------PTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDE-----MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPP-AHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQG----ACPYPPFMAAAAAAASAGLQFVN-LPPYRGPFSLSNSGPGRGQ-----------HWPP-------------------LPKFDPSVPP-------------------PGYMPRQED------------PHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVK-----SGEHKDEDRPKPKDRIAS------CLLESWGK-GEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAK---RDPKGVGVRRRPARPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEE-QESTEEEEEAE----EEEEEEVPRSQLSSSSTSSTSDKDDDDDD---SDDRD------ESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESS--------ESSEFESSSE--SSPSSSEDEEEVVARE---EEEEEEEEE-----------MVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEV-EARPPLSPERAPEHDLEVEPEPPMMLPLP-LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPG-----LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPA-VLRAQARAPTPLPPLLPAPLASCPPPMK-RKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKR---HEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAK---KKKRDDGI-REHVTGCARSEGFYTIDKKDKLRYLNSSR--ASTDEPPADTQG-------MSIPAQPHASTRAGSERRSEQRRLLSSFTG--SCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIE---DVKIPCLCGSENCRGTLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY77-1", "uniprot_id": "SE1BA_DANRE", "id": "Q1LY77-1", "name": "Histone-lysine N-methyltransferase SETD1B-A", "aln": "MCWKVEIVVYCKRQKPQTRGTQYVPGERNKLNEDHGRRQSSSLANGMDNSHPICSSGEKRSHHWRSYKLIID----PALKKGSHKVYRYDGHQFSTPSFGMSPVDIVRDPRIGRLWTKYKETDLPVPKFKIDECYVGRVPPKEVTFAKLNDNVREGFLTDMCKKFGDIEEVEILYNPKNKKHLGIAKVVFETVKAAKDAVQNLHNTSVMGNIIHVELDPKGENRQRYFQRLINGSYTPLTLPVGGEEACDVSPRSLAEALMACEPSRRLFEGGSSVVAG-----TTPSGTNTPMSLDTAYSSLRQDTP-QS---------------QGTPHTPRPSGTPFSQDSSYSSRQ----------------GTPAFQANRAESSGGYKSRRHET-----KFQDAYNR----------------------------------------------------------RPERRYVHG-----------PTQRGNTEQPPSFK---------QHQPPEPPSP--------------------AFTHTPPPP---TSANFKTAYSQ----------YQP-----PIPQE----------YTVASYHQP---------------------------------------VQRELDYR----RPPQAPPPPSTDFLP--------VRDRPTTPPIPEPPPAPETQPTTP-------------------------------------------PSS--TPEPCPSP---TQESE-------RNSLDSRIEMLLK------PFLNERGDSDAEVRMDGSP-----------ISSSSSQLSPIP-------------------PQRPS-RPSSTGLEDISPTPLPDS-EDDEPIRGTASLLANSRG-------MSPTNMHSKSCVGEPRTAIDKMDTGHQSSGEDMEISDDE-----MPGTPIASGDCDKNIVVN-------SALSLIQTIPMPPP-GFPPLP-------HAAGFPLPPHHLP--------HHSTVSHLP---------SHHPMLHPLHSY--GMMHFLPVDLLSSLP---QLLQMPFQMQTQMLSRMAQSQH----PYAYP---YPAPSANPAAMPFGGPYPPLSVVSAPADTLHGQPW-----------PLPS-------------------MPQFNPAVPP-------------------PGYEPQKED------------PHKATIDGVLMAIVKELKAIMKKDLNRKMVEVVAFRKFDEWWDKQELSAKATLTPVK-----TGEGKDEEKERAKPKETM------SSHLPWNK-GEGLGFEGMGLGIGLRG-IRLPSFKVKRKQPPEPTSTSDNKRVRPSTPVDDELEDEESERMG-----RTDGSR---VDPAGSSSKRRPARPLELDSEGEEEEETSGKEESSLSDHEEEPVDDASERLSSGKDLEEEDEKKSESHSSESESSDSSDDEAS----SSSSSKSGSDSSGSESS---SDYES------SSEEEEE----EEEEEERIVGMDDEEDVDARTSTSSSTTSTSSS---------DEEEVVEVKAPSTPTGPPPEEEPNELGRLEAVDEAEIDH--------------KPSMVSLIKTKVEEVR---PPSPKGLPAD----ELDVDLEVKIPVPKTEASLEEVGNL-----------RPPTPTGSFADSDQDTRPKIPTEDF-----PRTPGHEGPVPLESETTVPRSLPTPSMHLPLPPSHVPDPQSLLPPPET--LPDMPVRGRLPTEEDIPRTPGRDLMDRARGLGKLQSTDTVPVTPGSDTPLTGN----SLSSPHILGSPFSYPAQSPVLSAG-IPRTPGRDLTFAPAFPDSAG----LSAGLPIHRKASSEILEEKPLFKEPLLSASPQASLPNNAASSP--FPGPPLPTASLPEPALPPQGSPPASIENSFPASPKELPVPMIDVPVPLDDTPSKKKLVRSKNKK----------GIQDSEEPQVTLIEASSLPELPVNNQYPDLPSESIKEEDGEPAFSEKEESQVPTIIP-----KVEETSFYVEEPIQK---TRRQRRG---WQELLLSMHSPVASPRRPSFMPRSDFEEMTILYDIWNDGIDEEDIRYLKITYDKMLQQDNAHDWLNDTLWVHHPPTNMGSATGVKKKRKEDGI-RDHVTGCARSEGYYKIDKKDKMKYLNSSR--LQSEEPDVDTQG-------KSIPAQPQVSTRAGSERRSEQRRLLSSFS----CDSDLLKFNQLKFRKKKIRFCRSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSRQPINVNEEITYDYKFPIE---DEKIPCLCGAENCRGTLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PYH6-1", "uniprot_id": "SET1A_MOUSE", "id": "E9PYH6-1", "name": "Histone-lysine N-methyltransferase SETD1A", "aln": "-------------------------------------MDQEGGGD----------GQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPR-CHVRSKARDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGS-GAAAET-TEARRRSSSD-TAAYPAGTTVGGTPGNGTPCSQDTNFSSSRQDTP-SSFG-QFTPQSSQ-----GTPYTSR-GSTPYSQDSAYSSS---------------------------TTSTSFKPRRSEN-----SYQDSFSR----------------------------------------------------------RHFSTSSAPATTATATSATAAATAASSSSSSSSSSSSSSSSSSS-ASQFRGSD----------------SSYPAYYESWNRYQRHTSYPPRRATRE-----------DPSGASFAEN-------TAERFPPSYTSYLA------------------PEPN-----------------RSTDQDYR---PPASEAPPPEPPEPGGGGGGSGGGGGGGGGGGGGAPSPEREEARTPPR-----------------------------------------------PASPARSGSPAPETTNESVPFAQHSS-LDSRIEMLLKEQRSKFSFLASDTEEEEENSSAGPG-----------ARDAGAEVP------------------------------SGAGHGPCTPPPAPANFEDVAP-----------------------TGSGEPGAARESPKANGQNQASPCSSGEDMEISDDD------------RGGSPPPAPT-----PPQQPPPPPPPPPPPPPPYLASLP-----------LGYPPHQPAYLLP------PRPDGPPPPE-----YPPPPPPPPPHIYD----FVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAAS---AGPPGGAFGEAFLP--FPPPQEAAYGLPYALYTQGQEGRGSYSREAYHLP--------------------LPMAAEPLPS----------------SSVSGEEARLPHREEAEIAESKVLPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAK------QQAKEEDKEKMKLKEPG-----MLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPG--RPGTKPPKRDEERGKTQGKHRKSFTLDSEGEEASQESSSEKDEDDDDEDEEDEEQEEAVDATKKEAEASDGEDEDSDSSSQCSLYADSDGENGSTSDSESGSSSSSSSSSSS---SSSSS------SSESSSE----------EEEQSAVIPSASPP-REVPEPLPAP------------DEKPETDGLVDSPVMPLSEKETLPTQPAGPAEEP------------------PPS-VPQPPAEPPAGPPDAAPRLDERPSS--PIPLLPPPKKR-------RKTVSFSAA----------EEAPVPEPSTAAPLQAKSSGP-----------------------VSRKVPRVVERTIRNLPLDHASLVKSWPEEVA----RGGRNRAGGRVR---------------STEEEEATESGTEVDLAVLADLALT-------PARRGLATLP----------TGDDSEATETSDEAERP---------------SPLLS----HILLEHNYALAIKPPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEP-----------------------------------------------------------------------KQQLQQQ-HPEQEGEEEEEDEEEESESSESSSSSSS-DEEGAIRRRSLR---------------------SHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVQHTITNLSTPK--RKRRPQDGP-REHQTGSARSEGYYPISKKEKDKYLDVCP-VSARQLEGGDTQG----------------TNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLE---DNKIPCLCGTESCRGSLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6T6-1", "uniprot_id": "A0A0G2K6T6_RAT", "id": "A0A0G2K6T6-1", "name": "[histone H3]-lysine(4) N-methyltransferase", "aln": "-------------------------------------MDQEGGGD----------GQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPR-CHVRSKTRDFSLPVPKFKLDEFYIGQVPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSSGATTET-TEARRRSSSD-TAAYSAGTTVGGTPGNGTPCSQDTNFSSSRQDTP-SSFG-QFTPQSSQ-----GTPYTSR-GSTPYSQDSAYSSS---------------------------TTSTSFKPRRSEN-----SYQDSFSR----------------------------------------------------------RHFSASSAPATTATATSATAAATVASSSSSSSSSSSSSSSSSSSSASQFRGSD----------------SSYPAYYESWNRYQRHTSYPPRRATRE-----------DPSGAPFAEN-------TAERFPPSYTSYLA------------------PEPN-----------------RSTDQDYR---PPASEAPPPEPPEPGG---GSGGGGGGGSGGGGGAPSPEREEARTSPR-----------------------------------------------PASPARSGSPAPETTNESVPFAQHSS-LDSRIEMLLKEQRSKFSFLASDTEEEEENSSAGPG-----------ARDAGGEVP------------------------------SGAGHGPCTPPPAPANFEDVAP-----------------------TGSGEPGAARESPKANGQNQASPCSSGEDMEISDDD------------RGGSPPPAPT-----PPQQPPPPPPPPPPPPPPYLASLP-----------LGYPPHQPAYLLP------PHPDGPPPPE-----YPPPPPPPP-HIYD----FVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAAS---AGPPGGAFGEAFLP--FPPPQEAAYGLPYALYTQGQEGRGAYSREAYHLP--------------------LPMAAEPLPS----------------SSVSGEEARLPHREEAEIAESKALPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAK------QQAKEEDKEKMKLKEPG-----MLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPG--RPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEDDDEEDEEDEEREEAVDATKKEAEASDGEDEDGDSSSQCSLYADSDGEDGSTSDSESGSSSSSPSSSSS---SSSSS------SSESSSE----------EEEQSAVIPSASPPPREVPEPLPAP------------DEKPETDRVVDSPVMPLPEKETTSTQPAGPAEEP------------------PPN-IPQPPPEPPAGPPDPPPRLDERPSS--PIPLLPPPKKR-------RKTVSFSAT----------EEAPVPEPSTASPLQAKSPGP-----------------------VSRKVPRVVERTIRNLPLDHASLVKSWPEEVA----RGGRNRAGGRVR---------------STEEEEATESGTEVDLAVLADLALT-------PARRGLAAIP----------TGDDSEATETSDEAERP---------------SPLLS----HILLEHNYALAIKPPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEP-----------------------------------------------------------------------KQPLQQQQHPEQEGEDEEEDEEEESESSESSSSSSSSDEEGAIRRRSLR---------------------SHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLSTPK--RKRRPQDGP-REHQTGSARSEGYYPISKKEKDKYLDVCP-VSARQPEGVDTQG----------------TNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLE---DNKIPCLCGTESCRGSLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15047-1", "uniprot_id": "SET1A_HUMAN", "id": "O15047-1", "name": "Histone-lysine N-methyltransferase SETD1A", "aln": "-------------------------------------MDQEGGGD----------GQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVNDSKYIPVEDLQDPR-CHVRSKNRDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGS-GAATET-AESRRRSSSD-TAAYPAGTTAVGTPGNGTPCSQDTSFSSSRQDTP-SSFG-QFTPQSSQ-----GTPYTSR-GSTPYSQDSAYSSS---------------------------TTSTSFKPRRSEN-----SYQDAFSR----------------------------------------------------------RHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSS-SSQFRSSD----------------ANYPAYYESWNRYQRHTSYPPRRATRE-----------EPPGAPFAEN-------TAERFPPSYTSYLP------------------PEPS-----------------RPTDQDYR---PPASEAPPPEPPEPGG-------------GGGGGGPSPEREEVRTSPR-----------------------------------------------PASPARSGSPAPETTNESVPFAQHSS-LDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLG-----------ARDTGSEVP------------------------------SGSGHGPCTPPPAPANFEDVAP-----------------------TGSGEPGATRESPKANGQNQASPCSSGDDMEISDDD------------RGGSPPPAPT-----PPQQPPPPPPPPPPPPP-YLASLP-----------LGYPPHQPAYLLP------PRPDGPPPPE-----YPPPPPPPP-HIYD----FVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAAS---AGPPGGAFGEAFLP--FPPPQEAAYGLPYALYAQGQEGRGAYSREAYHLP--------------------MPMAAEPLPS----------------SSVSGEEARLPPREEAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAK------QQAKEEDKEKTKLKEPG-----LLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPG--RPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSS---SSSSS------SSSSSSESSSED---EEEEERPAALPSASPPPREVPVPTPAP------------VEVPVPERVAGSPVTPLPEQEASPARPAGPTEES------------------PPS-APLRPPEPPAGPPAPAPRPDERPSS--PIPLLPPPKKR-------RKTVSFSAI----------EVVPAPEPPPATPPQAKFPGP-----------------------ASRKAPRGVERTIRNLPLDHASLVKSWPEEVS----RGGRSRAGGRGR---------------LTEEEEA-EPGTEVDLAVLADLALT-------PARRGLPALP----------AVEDSEATETSDEAERP---------------RPLLS----HILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEP-----------------------------------------------------------------------KPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDG---EGALRRRSLR---------------------SHARRRRPPPPPPPPPPRAYEPRSEFEQMTILYDIWNSGLDSEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLTTPK--RKRRPQDGP-REHQTGSARSEGYYPISKKEKDKYLDVCP-VSARQLEGVDTQG----------------TNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLE---DNKIPCLCGTESCRGSLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PER0-1", "uniprot_id": "A0A8M9PER0_DANRE", "id": "A0A8M9PER0-1", "name": "", "aln": "-------------------------------------MDPDSGAD----------TQRTLSLQWKSYKLVQD----PALRRVTQKIYRYDGIHFSVPDSGFPPVGDLRDPRPRRIWSRHTELSLPVPKFKLDEYYVGPIPLKEVTFARLNDNIKEPFLAEMCAKFGEVEEMEILFHPKTRKHLGLARVLFTNTRGAKDTVKHLHNTSVMGNIVHVQLDIKGQQRMKYYDLIVSGSYTPQTVPTGGKALTEKFQPPVPTQPDTSSDIRRRLSTD-QMAAPAAATLN--SGSTTPCSVDTGFGDQRLDTPPSSMGGPYTPGSSASSQGGGTPYTPR-SGTPFSQDSGYSVARHGGYSSTQSFPQQDMLPSSSCSSSAVSSSSGFKPPRFHDDLHAPPPQDVFQRGRPGFPASAPFRPNEPPYPYPSAGGSGMHMPLHPPVPPQFEQPPLSDRERERDRERGHRDRERDSGGGRYGGGISSRRSTYPYQQETNSSSTSKTYHAHHSHHADRREDRDGRGYRRDSSGSRSGDHSRHRNHHHSHNHHSGGGGSSRRRSSRDREWERDRDGEFNPSDPRYGSHSNSSHHSSNSLSPPSATSSFGGFSSSKDLSPYDTPSSSRLEPSSAFRPQQGAGERAFGMGGSMDNDYRGHSHHTPLAPPPPPPPLPPASVIAAAVAETLSSLDFGQDSPIREEQWTKPKRHPSTPPLPPRTPPTSSPPHASIPSSSTSPSSTSLPHHLPSSTASLSPPPPQRDSSPEPDSTNESLPFMHHSSSLDSRIEMLLKEQKAKFSFLASDDEDDEKDEVRERGKSENSKDGGNKLREHGGERPSHKRQGEMEAGQQRRRGEKDGRRSRGKRQVSGVGEGRKTPPEVASSTPTVHSLVSESLQGQIPPPQ------EEHTTSDTHRAPHTPPTYNGEAQPSPRSSGEDMEISDEDDNTITTATSHPAASSSSSPAASSQTVLPSQTTDPSASPAPDTSQHFSATMPP-------PPIPSYPPHLPPPPLPGFSLQPPPPPGIPPPLPHMELHPEYPPPLPHHMYD----YASSMELMSQY---CGGAPMSFQMQTHMLSRLHQMRMASSNSTAAPPAEVPPASEYPPSYHLHSIPPPHAPPHHPHHPYMDQDGNVASHYDQDHRYIPPPLPYAYPDPHAAQLPHHHTIPPPHTPWPPHLLPQQFPSHYPPPGFGAVPGVDGELYGAAGDQMAIMGHNPCEAVVQQVLAALIEEMKNIMQRDLNRKMVENVAFGTFDEWWDRKERKAKPFQTAMRGVAVVREEEKKEEKTTTTMTTSNRPREPLMSLVDWAKSGGMEGFS-------LRGALRLPSFKVKRKEPQELVEGDELKRARPSTPPDEEDEDSYQGKSADAAAGRTEERRVAERGAARRRSRAKARKPYELDSEGEETSDGSSSEKEDEDSDKVDESEDEALSADSDDESVSSSSSESSSSSSASSSSSDEEDEEEGEQAAESESLDTMDESTMDSV---AAVDT------EKDERDKASLDQPSVTTPEDKQEEEKSATPVPPSSPYPRPSSPI----------LLLPPLKKRRKTVSFSMEESEVKPSVQSSTASSP------------------SPSPVSQASDVPPSVSPVSTPTPAAPSASSKPVPMLLPFASRPSESSALTSPASPSAI----------LTVPPPVRSLRPDEPKKSPGPPPSPQ-----TPPPKNSTKRGKDSPRTPPAPVCLTVQNLPLDHASMVKMAYEDPVPLP-TTQKGRARGRPRTLSQSASASH--LHPALEEEDEDEEELEQRLKLREQLGVSSLLQLASAPKPDLSVLADVALKMDP-EADIDSEETETSDEAEEHKLEEEEGDFFAPHPRQPLLDPEGLFVMQEHNYSKTPAPQHITPPQKKTKQDSTVLLPADLNQHGVQEAPEEVIGEALAARAEAPELYGDLDLLCDGREAAETQTKTLSSPYKRTGSISKEVELEERGKGKNKKRSRKDKENEELQTSKKQKEKQVKKQKKRKLEEFEEDVDVEQLESGELSSSTSDSGDSDFGLERSLEFEKEEVRKSERLFLQEAGLTPSTQRRPKHTPESLPIPRPSYKNRSEFEQMTILYDIWNSGLDQEDMRLLKSTYEKLLQDDHGTDWLNDTHWVPHTITNIPNPR--RKKKTADGQLREHVTGCARSEGYYAISRKEKDVYLELDQPVTLREIGDYDTAG----------------SNRVLSERRSEQRRLLSAIGTPAVMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQSIRQMVADNREKRYAQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVNEEITYDYKFPIE---ENKIPCLCGTESCRGTLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BBX9-1", "uniprot_id": "A0A8M3BBX9_DANRE", "id": "A0A8M3BBX9-1", "name": "", "aln": "-------------------------MCESVEKEGQRKVNDDLIIN------DSFHPLEDAAPNWSCYKLIID----PGLTSGSQKVYRYDGQHFSEPHPECFPVDVVRDPRITRFWAKFKNADLPVPKLKVDEYYVG--APKELTFARLNDNIRDGFLSEMCKCFGEIQDLKVFYNPKNKKHLGLAKVVFESVKAANNAVKNLHKTSVMGNNIHVELDPKGLKRHRYFQMIVNGLYTPFTLPVEEEAWGPQSPSSITDSLIECESLKKLTYTLSSSSSICNGSPS--LDCSTPLSMDTAYSSMHQDTPSSFWQ------------TPQYQDTPRTPSVTHSRPGTPSQCER---------------TPNESTLINTGPIVPFIQQSTLNISHFQPGQPAINK---------------------------------------------------------PSTIQHAVQNFWMLSGTPSHNGIFSNRQRTPGGNSHPSNHVRGGHRVRPLESKYQN------------------AYNRRPQHRHYIHRPVYRRGHYHRALATN-----QVTLNRFQETPT----------TPLYSDKLTG--------------------------------------RNFTDSIKG------LCVNHISVVEDP------------LSLPYSEKLPEKTNNHIHPD--------------------------------------------------IEKNVYASENTLTQTASPVPSKTTYDVNQNHYPSQAQSSHSYVPKLCSSPETTEDISEP----------TVECPSPEFPAPE---------------------------SKPDSLDTRIQMLLSAGSPVLPLLN------------------QDSSDSESTEENDHHQRSSRAPSPTQSLTTGVSLNYDDISSVVRDTSSYPRENLSGMEDVNPTALYDVAEDKHELPSPKKPLSKMPSSTIVN---------PNEDQDTSDQPSSIPVICTNRSTSTPPMS-----EIPPPPMPSVHYPFLPGYSLPTSSCSLYPPSIIKQVCRRSNWPTSLAPLPIPTR------ITQGQTSLSPSFLPQSFSFMTHRPPYPSPGCSSTMLRYRPP----------WPPPPP------------------IPRFDPSVPP-------------------PGYVPIKES------------PHKATVDGVLAVVASELRAIVKKDIHRRMIEIMAFKAFDQWWDDKEQAAKVSAPAVK------SVGNKDIKLRVMEQSLR-----------LGTAGGEGCILDSGKIKSLHGAIKLPSFKRKG---PSGQGSTDVKRICPSPGPEHSEDEESEQQTAPDCVDETTVLN----ASEDTMVKRRHSRPLALDSEEEDDEENSEKAEDPKPEQVHACDRVDIKKVTKDQTSDPCVIVDDEDTDTETLSHSNSSASKSQGYDSLASPRSASHYSACSPSVIDSPVSSRPVFVSSDDRSDESSSVSSAEDDQSDGQSSPETPREDRRVVETIWISSDE--------DDDENQETLHTPVFLPSPHSEEDLQPPVTPSAPDSIESDVDN-------DFFDLDPAQMEDPEEELSVRVYMQGLKLPEPLRYTLQDPVKHCLTNKLKLPDPVIFFSDQESE------------LPSPPSPTYRGLSDDLETQYTTDS-----------------EDQRVIMEALEDPVHLRPITPTGFLSDSDPDIEMGRKFSPPAIEEVDLP--------------HTPGRCLELEDDENNILPPGPPTPLPPPPSPTGIKELPSSPLYYGIPLLSSYPGYEEIPKTPGRVNDPGFVFHSER---------ITPPQEPSRTLESPCNPFLSSFADSGIPRTPGRDMSLSPPVLNHRERHVQHRELLKYGQRHRNSDFAQ----------------------------------------------SDVQTNNFSKNNSHTPRSDTARLKRRRERLKKRQRMIELQRSRRCTDLNTHSSLQVSSATTKPTNQSLEPLDRVSNIRTEESNNSQQIETQRLSESSYVRRDSSLTPHLIFTPRSKRREKLVLHAVWTKGVNEEEIRHLKASYERLVVEDNEYDWLRRTRWIPHPPTSTSDDR---PRRWLDGV-RNHLTGCARSEGYYFISKREKLQYLCNER--TVSEEFTADSQG-------KSVSAQVSHSSRSGSELRAEQRRLLSSFS----CDSDLLKFNQLKFRKKRLRFGKSRIHDWGLFAEEPIAADEMIIEYVGQSIRQVIADMRERRYETEGIGSSYLFRVDHDTIIDATKCGNLARFINHSCNPNCYAKVITVEAQKKIVIYSRQPITVNEEITYDYKFPIE---DEKIPCLCAAENCRGTLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5LJZ2-1", "uniprot_id": "SET1_DROME", "id": "Q5LJZ2-1", "name": "Histone-lysine N-methyltransferase SETD1", "aln": "--------------------------MQDVRNINLVNNSSNSHDS-----------SLANSKMPRNFKLLSD----PQLVKCGTRLYRYDGLMPGDPSYPTITPRDPRNPLIRIRARAVEPLMLLIPRFVIDSDYVGQPPAVEVTIVNLNDNIDKQFLASMLDKCGTSDEINIYHHPITNKHLGIARIVFDSTKGARQFVEKYNQKSVMGKILDVFCDPFGATLKKSLESLTNSVAGKQLIGPKVTPQWTFQQAALEDTEFIHGYPEKNGEHIKDIYTTQTNHEIPNRSRDRNWNRDKERERDRHFKERSRHS--------SERSYDRDRGMRENVGTSIRRRRTFYRRR-------------------SSDISPEDSRDILIMTRERS-----RDSDSRPRD-------------------------------------------------------YCRSRERESFRDRKRSHEKGRDQPREKREHYYNSSKDREYRGRDRDRSAEIDQRDRG----------------SLKYCSRYSLHEYIETDVRRSSNTISS-------YYSASSLPIASHGFN---------SCSFPSIEN---------------------------------------IKTWSDRR--------AWTAFQPDFHP--------------VQPPPPPPEEIDNWDEEE------------------------------------------------HDKNSIVPTHYGCMAKLQPPVPSNVNFATKLQSVTQPNSD-----PGTVDLDTRIALIFKG------------KTFGNAPPFLQMD------------------------SSDSETDQGKPEVFSDVNSDSNN-----------------------SENKKRSCEKNNKVLHQPNEASDISSDEELIGKKDK-----------------------------SKLSLICEKEVNDDNMSLSSLS----------------------------------------------------------------SQEDPIQTKEGAEYKSIMSSYMYSHSNQNPFYYHASGYGHYLSGIPSESASRLFSNGAYVHSEYLKAVASFNFDSFSKPYDYN---------------------------------------------------------------KGALSDQND------------GIRQKVKQVIGYIVEELKQILKRDVNKRMIEITAFKHFETWWDEHTSKARSKPLFEKADSTVNTPLNCIKDTSYNEKNPD-------INLLINAHREVADFQSYSSIGLRAAMPKLPSFRRIRKHPSPIPTKRNFLERDLSDQEEMVQRSDSDKEDSNVEISDTARSKIKGPVPIQESDSKSHTSGLNSKRKGSASSFFSSSSSSTSSEAEYEAIDCVEKARTSEEDSPRGYGQRNLNQRTTTIRNRNLVGTMDVINVRNLCSGSNEFKKENVTK------------------------------RTKKNIYSDTDEDNDRTLFPALKEKNIS----------TILSDLEEISKDSCIGLDENGIEPTILRKIPNTP--------------------------KLNEECRRSLTPVPPPGYNEEEIKKKVDCKQKPSFEYDRIYSDSEEEKEY--------------QERRKRNTEYMAQMEREFLEEQ-------------------EKRIEKSLDKNLQSPNNIVKNNNSPRNKNDETRKTAISQTRS--------------------CFESASKVDTTLVNIISVENDINEFGPHEEGDVLTNGCNKMYTN--------SKGKTKRTQSPVYSEGG--------------------------------SSQASQASQVALEHCYSLPPHSVSLGDYPSGKVNETKNILKREAENIAIVS-------------------------------------------------------------------QMTRTGPGRPRKDPICIQKKKRDLAPRMSNVKSKMTPN--------------------------------GDEWPDLAHKNVHFVPCDMYKTRDQNEEMVILYTFLTKGIDAEDINFIKMSYLDHLHKEPYAMFLNNTHWVDHCTTDRAFWPPPSKKRRKDDELIRHKTGCARTEGFYKLDVREKAKHKYHYAKANTEDSFNEDRSDEPTALTNHHHNKLISKMQGISREARSNQRRLLTAFGS--MGESELLKFNQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRETKYEAIGIGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQPIGINEEITYDYKFPLE---DEKIPCLCGAQGCRGTLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38827-1", "uniprot_id": "SET1_YEAST", "id": "P38827-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-4 specific", "aln": "------------------------------------------MSN----------YYRRAHASSGSYRQPQE-----QPQYSRSGHYQYSNGHSHQQYSSQYNQRRRYNHNDGTRRRYNDDRPHSSNNASTRQYYATNNSQSGPYVNKKSD-------ISSRRGMSQSRYSNSNVHNTLASSSGSLPTESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKG-EFFNKDKMLSWKATDKEFSETGYYVVKELQDGQFKFKIKHRHPEIKASDPRNENGIMTSGKVATHRKCRNSLILLPRISYDRYSLG--------------------PPPSCEIVVYPAQDSTTTNIQD-------------------------ISIKNYFKKYGEIS------HFEAFND----------------------------------------------------------------------------------------------------------------------------------------PNSALPLHVYLIKYASSD-----------------------------------------------------------------------------------------------------------------------------GKINDAAKAAFSAVR---------------------------------------------------KHESSGCFIMGFKFEVILNKHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEK-------------------------------------------------------------------------------------------------AKELQGKDITLPKEPKVDTLSHSSGSEKRIPYDLLG------------------------------VVNNRPVLHVSKIFVAKHR----------------------------------------------------------------FCVEDFKYKLRGYRCAKFIDHPTGIYIIFNDIAHAQTCSNAESGNLTIMSRSRRIPILIKFHLILPRFQNRTRFNKSSSSSNS----------------------------------------------------------------TNVPIKYE------------SKEEFIEATAKQILKDLEKTLHVDIKKRLIGPTVFDALDHANFPELLAKRELKEKEK---------RQQIASKIAEDELK------------RKEEAKRDFDLFG----LYGGYAKSNKRNLKRHNSLALDHTSLKRKKLSNG----------------------------------------IKPMAHLLNEETDSKETTPLNDEGITRVSKEHDEEDENMTSSSSEEEEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSM----------------------------------------------------------------------YKPTATEIPEPVYPPEEYDLKYSQTLSSMDLQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AIKDEEDMLILKQLLSTYTPTVTP----------------------------------ETSAALEYKIWQSRRKVLEEEKASDWQIELNGTLFDSELQPG--SSFKAEGFRKIADKLKINYLPHRRRVHQPLNTVNIHN-------------------ERNEYTPELCQREESSNKEPSDSVPQEVSSSRDNRAS---------------NRRFQQDIEAQKAAIG--------TESELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : *:*.. : . . * . . . .* . . : : . * . .. : . .. * . . : : : . . : . . . . . * : . : . : .::. :: *:::::: .* :: . : : . . .. : . . * . . : .. . . . . * . : . : : . :: : : . :* : : . *.* : ::: * : .::: : :*:**.:***: *** : * :* **:***:* :.***.**:*****: ** :*: ** :* ******:**:* :*:***** *.:******.* *** **:*.: ..::****: : * .**:****** * : ::****.: .*:* **", "identical_positions": 99, "similar_positions": 146, "identity": "4.1%" }, { "cls_id": "homologset.agr.SGD:S000001163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MHD2-1", "uniprot_id": "LSM12_HUMAN", "id": "Q3MHD2-1", "name": "Protein LSM12", "aln": "------MAAP-PGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSG---KPNHADILLINLQYVSEVEIINDRT--ETPPP----LASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKT--IKDCKWQEKN----IVVMEEVVITPPYQVENCKGKEG---SALSHVRKIVEKHFRD-----VESQKILQRSQAQQPQKEAALSS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0R8-1", "uniprot_id": "LSM12_MOUSE", "id": "Q9D0R8-1", "name": "Protein LSM12", "aln": "------MAAP-PGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSG---KPNHADILLINLQYVSEVEIINDRT--ETPPP----LASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKT--IKDCKWQEKN----IVVMEEVVITPPYQVENCKGKEG---SALSHVRKIVEKHFRD-----VESQKILQRSQAQQPQKEAALSS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM11-1", "uniprot_id": "A0A8I6GM11_RAT", "id": "A0A8I6GM11-1", "name": "", "aln": "------MAAP-PGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSG---KPNHADILLINLQYVSEVEIINDRT--ETPPP----LASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKT--IKDCKWQEKN----IVVMEEVVITPPYQVENCKGKEG---SALSHVRKIVEKHFRD-----VESQKILQRSQAQQPQKEAALSS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBA2-1", "uniprot_id": "LS12A_DANRE", "id": "Q6PBA2-1", "name": "Protein LSM12 homolog A", "aln": "------MAAPGPGEYFSVGSHVSCLTCLGQRLQGEVVAFDYPSKMLTLKCPSSSG---KPNLSDVILINLAYVSEVDIINDRT--ETPPP----LASLNISKLANRARTEKEDKLSQAYAISAGVSIEGQQLFQTIHKT--IKDCKWQEKN----IIVMDDVVISPPYQVENCKGKEG---SALSHIRKIVEKHFRD-----VESQKTMQRSQAQQTQKDSSLSS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NSN1-1", "uniprot_id": "LS12B_DANRE", "id": "Q6NSN1-1", "name": "Protein LSM12 homolog B", "aln": "------MAAPGPGEYFSVGSHVSCLTCLGQRLQGEVVAFDYPSKMLTLKCAPSSG---KPNLSDVMLVNLAYVSEVDIITDRA--ETPPP----LASLNFNKLVNRARAEKEDKLSLAYAVSAGVSVEGQQLFQTIHKT--IKECKWQEKN----IIVMDDVVISPPYQVDNCKGKEG---SALSHVRKIVEKHFRD-----VESQISVQHSQQAQHTQDSALSS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR0-1", "uniprot_id": "LSM12_DROME", "id": "Q9VYR0-1", "name": "LSM12 homolog A", "aln": "MAAAAASAVNAVNDCFSIGSTVVCTTCFNEEVEGEVLAFDHNTKMLILKCRSKS----TEELSDIYAMNLSLCSNVQVIKECN--GNFDD----PQKLNLEQVKMRLRKTVERRQDYLKSKNADVSPEAQELYRAIAKQYGYNEVSWQGLN----IQILNEVTISPPYRVDNVVSSSNNE-TSCNYIKRIIKQFFNTRPSPVPESGAAASTSSPSVSPTSSSLASGSPVPAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT67-1", "uniprot_id": "HEZ_DROME", "id": "Q9VT67-1", "name": "LSM12 homolog B", "aln": "--------MSSLAPCFTVGSIVRCKTCFGDNISGEVVAFDLGVKMLIMKCPSSNGGGDEQTTCNVTIVNLSLCMDIEIVKEAIPPAEVQQ----PEPIDLPMIRERYRYATEHRTLSCRSYHPNASPFGQALFRLLVKRFGDPAIIWQNKGDQVAINILRQVVIDAPYATENIRYLDWNP-KLAICVQEVVQNFCSKQF---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38828-1", "uniprot_id": "LSM12_YEAST", "id": "P38828-1", "name": "Protein LSM12", "aln": "---------MSVSLEQTLGFRIKVTNVLDVVTEGRLYSFNSSNNTLTIQTTKKNQ-----SPQNFKVIKCTFIKHLEVIGDKPSFNSFKKQQIKPSYVNVERVEKLLKESVIASKKKELLRGKGVSAEGQFIFDQIFKT--IGDTKWVAKD----IIILDDVKVQPPYKVEDIKVLHEGSNQSITLIQRIVERSWEQ-----LEQDDGRKGG--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : . .*.: :*: : * :: .. :. :: .:::: : ::. : : ..* .* :: : * * . * :: :* : .** .:: ::.:::. ", "identical_positions": 12, "similar_positions": 51, "identity": "5.17%" }, { "cls_id": "homologset.agr.SGD:S000001164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8Q7-1", "uniprot_id": "D3Z8Q7_RAT", "id": "D3Z8Q7-1", "name": "Cytosolic iron-sulfur assembly component 2B", "aln": "----------------------------MVGGGGGGGGG------------------GLLENANPLIYERS------GERPVTAGEEDE---------EVPDSIDAR--EIFDLIRSINDPEHPLTLEELNVVEQVRIQVSDPEST-----VAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D187-1", "uniprot_id": "CIA2B_MOUSE", "id": "Q9D187-1", "name": "Cytosolic iron-sulfur assembly component 2B", "aln": "----------------------------MVGGGGSGGG--------------------LLENANPLIYERS------GERPVTAGEEDE---------EVPDSIDAR--EIFDLIRSINDPEHPLTLEELNVVEQVRIQVSDPEST-----VAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3D0-1", "uniprot_id": "CIA2B_HUMAN", "id": "Q9Y3D0-1", "name": "Cytosolic iron-sulfur assembly component 2B", "aln": "----------------------------MVGGGGVGGG--------------------LLENANPLIYQRS------GERPVTAGEEDE---------QVPDSIDAR--EIFDLIRSINDPEHPLTLEELNVVEQVRVQVSDPEST-----VAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTC4-1", "uniprot_id": "GALL2_DROME", "id": "Q9VTC4-1", "name": "MIP18 family protein galla-2", "aln": "----------------------------MPT---------------------------EIENINPNVYDRI------KERVLTANEEDE---------NVPDPFDKR--EIFDLIRNINDPEHPLTLEELHVVQEDLIRINDSQNS-----VHISFTPTIPHCSMATLIGLSIRVKLLRSLPPRFKVTVEITPGTHASELAVNKQLADKERVAAALENNHLAEVINQCIAAKG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38829-1", "uniprot_id": "YHS2_YEAST", "id": "P38829-1", "name": "MIP18 family protein YHR122W", "aln": "MSEFLNENPDILEENQLPTRKEDSTKDLLLGGFSNEATLERRSLLLKIDHSLKSQVLQDIEVLDKLLSIRIPPELTSDEDSLPAESEDESVAGGGKEEEEPDLIDAQ--EIYDLIAHISDPEHPLSLGQLSVVNLEDIDVHDSGNQNEMAEVVIKITPTITHCSLATLIGLGIRVRLERSLPPRFRITILLKKGTHDSENQVNKQLNDKERVAAACENEQLLGVVSKMLVTCK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9H5X1-1", "uniprot_id": "CIA2A_HUMAN", "id": "Q9H5X1-1", "name": "Cytosolic iron-sulfur assembly component 2A", "aln": "-----------------------------------------------------------MQRVSGLLSWTLS-----RVLWLSGLSEPG-------AARQPRIMEEKALEVYDLIRTIRDPEKPNTLEELEVVSESCVEVQEINEEE--YLVIIRFTPTVPHCSLATLIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCVLEPD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : :.. .* . * :: : *::*** * ***:* :* :* **. : : : . * : :***:.***:****** ::*:* *.** :.:: : :. *** :* :***: ******** ** :* ::.: : ", "identical_positions": 51, "similar_positions": 47, "identity": "21.89%" }, { "cls_id": "homologset.agr.SGD:S000001165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F7D7-1", "uniprot_id": "B4F7D7_RAT", "id": "B4F7D7-1", "name": "Ethanolaminephosphotransferase 1", "aln": "MKRRRQWGGGTWRWLSCSDWVKAVLGADRVRGGVPTRGSLEGCACALGGLRVRGGRSAPLPSLPAQAFLTLHIAVRCSCFLTLSSSVAAAAEWAFSFRVIMAGYEYVSPEQLAGFDKYKYSALDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASA--PGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWACVYFVVTVYSIFGRG-PTGVSVFVLYLLLWVVLFSFILSHWEKYNTGVL-FLPWG--YDISQVTISFVYIVTAVVGVEAWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFYRSYKSNSLKHNSIYEAMVPFFSPCLLFTLSTVWILRSPSDILEMHP-----RIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLFLVVATVIVGTTTS-----RLESVLLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRK-------PNSD-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TA1-1", "uniprot_id": "EPT1_MOUSE", "id": "Q80TA1-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MAGYEYVSPEQLSGFDKYKYSALDTNPLSLYIMHPFWNTIVKVFPTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASA--PGHKHVPDWVWIVVGILNFAAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRG-PTGVSVFVLYLLLWVVLFSFILSHWEKYNTGVL-FLPWG--YDISQVTISFVYIVTAVVGVEAWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKSNTLKHKSVYEAMVPFFSPCLLFTLCTVWILWSPSDILEIHP-----RIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLLLVVAAVIVGAATS-----RLESALLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRK-------PNSDULGMEEQNIGL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0D9-1", "uniprot_id": "EPT1_HUMAN", "id": "Q9C0D9-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MAGYEYVSPEQLAGFDKYKYSAVDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFLLVVFNFLLMAYFDPDFYASA--PGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRG-STGVSVFVLYLLLWVVLFSFILSHWEKYNTGIL-FLPWG--YDISQVTISFVYIVTAVVGVEAWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKNNTLKLNSVYEAMVPLFSPCLLFILSTAWILWSPSDILELHP-----RVFYFMVGTAFANSTCQLIVCQMSSTRCPTLNWLLVPLFLVVLVVNLGVAS------YVESILLYTLTTAFTLAHIHYGVRVVKQLSSHFQIYPFSLRK-------PNSDULGMEEKNIGL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAB3-1", "uniprot_id": "A0A8M1PAB3_DANRE", "id": "A0A8M1PAB3-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MALYHYVTQEQLSGFDKYKYSAVDSNPLSIYVMHPFWNSVVKVLPTWLAPNLITFTGFMFLVLTFTMLSFFDFDFYASG--EGHTHVPSWVWIAAGLFNFLAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWACVFFVATVYSVFGRG-ETGVSVVTLYYLLWVVLFSFILSHWEKYNTGIL-FLPWG--YDISQVTISIVYIITAVVGVETWYKPVFLN---IHYRDLFTVMIIGCLFVVTLPMSLYNVFKAYRNNTLKHSSLYEALLPFFSPVLLFVLSTLWISFSPTNIVQKQP-----RIFYLMVGTAFSNVTCKLIVCQMSNTRCKPLSLLLLPMSIVVLLVISGTVQ------GGESLVLFIWTAVVLLTHIHYGVSVVKQLSDHFNIFAFSLKK-------PNSD--UQDEEKIGLKAAEV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIU4-1", "uniprot_id": "Q9VIU4_DROME", "id": "Q9VIU4-1", "name": "Ethanolaminephosphotransferase 1", "aln": "---------------------------------------------------------------------------------------------MRQLFRRLMNHQYLTQDQINGFDNYKYSAIDTSPLSQYVMHPFWDWLVKFFPRWFAPNLMTFLGFLFSAMNLVLLSYYDWNFDASSGEEGTTPIPSWVWLCTAINIFLAYTLDGIDGKQARRIGLSGPLGELFDHGLDSYTAMLIPTCLYSIFGRSRVYSVRPMRMYYVCLTVYFNFFISHWEKYNTGIL-YLPWG--YDLSMWGSTAMYLVTWWMGFERWKFELPLGSYGTLPLGNVMEAVLHVSAMANLPLVIINVYNSYAHRTGRLLSFWEAVRPMWPFITYFVILLAWPYVSPNDIMEKDP-----RAIFMLSGTIFSNVSCRLIVSQMSVTRCEAWHWQTP---MFILSFLTSLWIP-----LLERPLLYLLLIVTTLSHWQYGASVVNQMCEHFNRVCFTVHKRVPQEELPKKKTLLAEEISQADKPQAEEPLKKDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8C025-1", "uniprot_id": "CHPT1_MOUSE", "id": "Q8C025-1", "name": "Cholinephosphotransferase 1", "aln": "----------------------------------------------------------------MAAGAGARP-----APRWVKALG-----------------EPLSAAQLRRLEEHRYTAVG-ESLFEPPLQLYWTWLLQWIPLWMAPNTITLIGLAINLVTTLVLIFYCPTVTEEA--------PYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLG----THPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD--VTEIQVALVIVFMLSTFGGATMWDYTIPILE---IKLKIVPVLGVVGGLIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNMFEKHP-----CLYTLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFI-------DEYVVLWIAMVISSFDMMIYFTSLCLQISRHLHLNIFKTSC-------QQAPEQVYKHID---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H21-1", "uniprot_id": "CHPT1_RAT", "id": "Q66H21-1", "name": "Cholinephosphotransferase 1", "aln": "----------------------------------------------------------------MAAGAGARP-----APRWVKALG-----------------EPLSAAQLRRLEDHRYSAAG-ESLFEPPLQLFWTWLLQWIPLWIAPNTITLFGLAINLFTTLVLIFYCPTVTEEA--------PYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLG----THPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD--VTEIQVALVIVFLLSTFGGAMMWDYTIPILE---IKLKILPVLGVVGGLIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNVFEKHP-----CLYTLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFI-------DEYVVLWIAMVITSFDMMIYFSSLCLQISRHLHLSIFKTSY-------QQAPEQVHKHID---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGS7-1", "uniprot_id": "CEPT1_MOUSE", "id": "Q8BGS7-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAG-RSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQA--------PLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLN---IQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHP-----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKA-------STAHSNHH-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM5-1", "uniprot_id": "CEPT1_RAT", "id": "Q6AXM5-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCILNKLFQLPTPPLSRHQLKRLEEHRYQSAG-RSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQA--------PLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLN---IQMKLFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHP-----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKT-------STAHSNHH-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6K0-1", "uniprot_id": "CEPT1_HUMAN", "id": "Q9Y6K0-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAG-RSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQA--------PLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID--VTEVQIFIIIMHLLAVIGGPPFWQSMIPVLN---IQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHP-----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKV-------STAHSNHH-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22140-1", "uniprot_id": "EPT1_YEAST", "id": "P22140-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "------------------------------------------------------------------------------------------------------MGYFVPDSHIENLKSYKYQSEDRSLVSKYFLKPFWQRFCHIFPTWMAPNIITLSGFAFIVINVLTVFYYDPNLNTDT--------PRWTYFSYALGVFLYQTFDGCDGVHARRINQSGPLGELFDHSIDAINSTLSIFIFASETGMG-----FSYNLMLSQFAMLTNFYLSTWEEYHTHTLYLSEFSGPVEGILIVCVSLILTGIYGKQVIWHTYLFTITVGDKVIDVDTLDIVFSLAVFGLVMNALSAKRNVDKYYRNSTSSANNITQIEQDSAIKGLLPFFAYYASIALLVWMQPSFITLSFILSVGFTGAFTVGRIIVCHLTKQSFPMFNAPMLIPLCQIVLYKICLSLWGIESNKIVFALSWLGFGLSLGVHIMFMNDIIHEFTEYLDVYALSIKR-------SKLT-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: :..::* : . : :: :* . .* *:*** :*: *: : . : :: . * *.:: . * ::*. ** :*** . . ********. *: . : . * : *: * : * . : : * . : . : : :. :. : * : ::::.::: . : : : : :: ::. : ", "identical_positions": 33, "similar_positions": 78, "identity": "6.16%" }, { "cls_id": "homologset.agr.SGD:S000001170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3Q5-1", "uniprot_id": "A0A8I6G3Q5_RAT", "id": "A0A8I6G3Q5-1", "name": "Uracil phosphoribosyltransferase homolog", "aln": "MATELQRPDSMPCHNRQVNSTSSPSPERLLAEDPVLDHAEENNAAMAKLTLLPGHAHSSVLSERDSPACCSTNLHCENHSDSSDSGNYEAPVG-DSLLGDCELYPQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIHRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHP-------VAP--THFGQKYFGTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVZ0-1", "uniprot_id": "UPP_MOUSE", "id": "B1AVZ0-1", "name": "Uracil phosphoribosyltransferase homolog", "aln": "MASELQRPDSMPCHNRQVNSTSSPSPEHLLAEDRVLDHAEENNAAMAKLTLLPGHAHSSVLSERDSPACCSTNLHSENHSDSSDSGNYDAPVGGDSLLGDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIHRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHP-------VAP--THFGQKYFGTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BW1-1", "uniprot_id": "UPP_HUMAN", "id": "Q96BW1-1", "name": "Uracil phosphoribosyltransferase homolog", "aln": "MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAG-NSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHP-------VAP--THFGQKYFGTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYU7-1", "uniprot_id": "UPP_DANRE", "id": "Q6NYU7-1", "name": "Uracil phosphoribosyltransferase homolog", "aln": "----------MPCHNQQLNNNSE-SPE---------------------------HAAKHVRFAQSSAAAAETCQNDAEQPEYQTTS---------------EIHQQIGPQLKLLPLNDQIRELQTIIRDKTTSRGDFVFCADRLIRLVVEEGLNQLPYSECTVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQKAKVYYAKFPPDISRRKVLLMYPILSTGNTVIEAVRVLTEHGLQAKHIILLSLFSTPHGARSIVQEFPDITILTTEVHA-------VAP--THFGQRYFGTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHI7-1", "uniprot_id": "M9PHI7_DROME", "id": "M9PHI7-1", "name": "Uracil phosphoribosyltransferase homolog", "aln": "------------MRTGSPSSSGSQSEE--------------------------GSSSSDHQQPQQEAQEQEQQLHTPTHAHAAVPAATS-----------EEILAEYGSNLKLLECNSQVAELLTILRDKNTTRSDFKFYADRLIRLVIEESLNQLPYTHCDVETPTGAIYEGLKYRSGNCGVSIIRSGEAMEQGLRDCCRSIRIGKILVESDANTHEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGVPESCIILSNLFCTPIAARTVVNAFPKLKILTSELHP-------VAP--NHFGQKYFDCI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18562-1", "uniprot_id": "UPP_YEAST", "id": "P18562-1", "name": "Uracil phosphoribosyltransferase", "aln": "------------------------------------------------------------------------------------------------------MSSEPFKNVYLLPQTNQLLGLYTIIRNKNTTRPDFIFYSDRIIRLLVEEGLNHLPVQKQIVETDTNENFEGVSFMGKICGVSIVRAGESMEQGLRDCCRSVRIGKILIQRDEETALPKLFYEKLPEDISERYVFLLDPMLATGGSAIMATEVLIKRGVKPERIYFLNLICSKEGIEKYHAAFPEVRIVTGALDRGLDENKYLVPGLGDFGDRYYCV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: ** ..*: * **:*:*.::* ** * :**:***::**.**:** . * * *. :**:.: *****:*:**:***********:******:: * :* .:: * ::* ** * *:*: *:::**.:.: *..** ::*: . * : .*:.: . .. **.: *:* :. :.* .**::*: ", "identical_positions": 79, "similar_positions": 70, "identity": "24.76%" }, { "cls_id": "homologset.agr.SGD:S000001171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5C5-1", "uniprot_id": "ACTY_MOUSE", "id": "Q8R5C5-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGADFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AKZ9-1", "uniprot_id": "A0A8I6AKZ9_RAT", "id": "A0A8I6AKZ9-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGADFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42025-1", "uniprot_id": "ACTY_HUMAN", "id": "P42025-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGVDFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61163-1", "uniprot_id": "ACTZ_HUMAN", "id": "P61163-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P85515-1", "uniprot_id": "ACTZ_RAT", "id": "P85515-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61164-1", "uniprot_id": "ACTZ_MOUSE", "id": "P61164-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45889-1", "uniprot_id": "ACTZ_DROME", "id": "P45889-1", "name": "Actin-related protein 1", "aln": "---MEPYDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRR-EGFNFRSTAEFEIVRSIKEKVCYLATNPQKEE-----TVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38696-1", "uniprot_id": "ARP1_YEAST", "id": "P38696-1", "name": "Centractin", "aln": "MDQLSDSYALYNQPVVIDNGSGIIKAGFSGEERPKALEYCLVGNTKYDKVMLEGLQGDTFIGNNAQKLRGLLKLRYPIKHGVVEDWDSMELIWSYVLNEVLQLQNIGEHPLLITEAPMNPLKNREQMAQVLFETFDVSALYVSNPAVLSLYASGRTTGCVVDCGEGYCSTVPIYDGFALPASMMRMDIGGADITEQLQFQLRKSAGVSLFSSSEREIVRTMKEKVCYLAKNIKKEEEKYLQGTQDLISTFKLPDGRCIEVGNDRYRAPEILFSPQIIGLGYDGLSDMCMQSIWKVDLDLRKPLLSSIILSGGTTTLKGFGDRMLWDLEALTKGTSKIKIIAPSERKYTTWIGGSILTGLSTFQRLWTKKSDWLEDSTRVYSNLM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : ***********:*****:*:. ** :*..*: :** .*:** *:* :*:: ****.:***::**:* **:.** **.*: .: :**:*:****:** :***: *:.:** ::..**::* *******:**.** *:*.*:* :****:***:* *:**:**.* *::. *: :*: * .: :::* *:*:::**:.***: * :*:* : : **** :::* *:****:** *:::* :*: :: :* * *:***: * .*:****:* :******:* ::: : **:* **.** *:**:*****:.*.**:::* .* :: *:. : . ", "identical_positions": 164, "similar_positions": 118, "identity": "42.6%" }, { "cls_id": "homologset.agr.SGD:S000001174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W478-1", "uniprot_id": "Q9W478_DROME", "id": "Q9W478-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKTMLLQLLLLVAAVA----ASLANELPSNLTLLDANEIP------QRYDEAQLWRIYNISE---AMQKRVPVGQMLEQKFGGNIWK----------------ENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFGHGRR-----TKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRE-----NKKVWIDGGIHAREWISPATVTFILYQLMSDWE--------------NQPAHIRGLTWYIMPVMNPDGYEYSRT--TNRLWRKNRSPSRRAQ--CSGVDLNRNFDIG-WNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKR---KYNLESYLTFHSYGQMIVYPWAYK-AVKVKDASVLQRVSSLAAERILQKTG---TSYRAA-VTHEVLGI--AGGGSDDWSRAALGVKYVYTIELR---DRGAYGFVLPPRFIKDTALEGWTVVETVAQAIGP--------SSSG-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W475-1", "uniprot_id": "Q9W475_DROME", "id": "Q9W475-1", "name": "Peptidase M14 domain-containing protein", "aln": "MYNARSRGSAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYMLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTD---KDKR---MADELQSKYDGQLWK----------------EVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQN---------RKGHR--LTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNAR-----NPGIWIDGGMHAREWISPATVTYIANQLVEGWE--------------DLPEHMRSINWYIHPVANPDGYEYSHT--TDRLWRKN-MRAHGRQ--CPGVDLNRNFGYK-WGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFP--RETFQAYLSFHSYGQYILYPWGYD-YQLTQDRADLDRVARQAGTSITKSTG---VKYTVG-SSATTLYP--AAGGSDDWAKGIAGIKYAYTIEMG---DTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSGSRRRGH-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19222-1", "uniprot_id": "CBPA2_RAT", "id": "P19222-1", "name": "Carboxypeptidase A2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLTLLLAALLG-------------------YIYCQETFVGDQVLEIIPSH----EEQIRTLLQLEAEEHLELDFWK-------------SPTIPGETVHVRVPFASIQAVKVFLESQGIDYSIMIEDVQVLLDQEREEMLFNQQRE------------RGGN-FNFEAYHTLEEIYQEMDNLVAENPGLVSKVNLGSSFENRPMNVLKFSTGGD------KPAIWLDAGIHAREWVTQATALWTANKIASDYGT-----------DPAITSLLNTLDIFLLPVTNPDGYVFSQT--TNRMWRKTRSK-RSGS-GCVGVDPNRNWDAN-FGGPGASSSPCSDSYHGPKPNSEVEVKSIVDFIKS---HG-KVKAFITLHSYSQLLMFPYGYK-CTKPDDFNELDEVAQKAAQALKRLHG---TSYKVG-PICSVIYQ--ASGGSIDWAYD-LGIKYSFAFELR---DTAFYGFLLPAKQILPTAEETWLGLKTIMEHVRDHPY--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q504N0-1", "uniprot_id": "CBPA2_MOUSE", "id": "Q504N0-1", "name": "Carboxypeptidase A2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLTPLLVALFG-------------------YIYCQETFVGDQVLEVIPND----EEQIKTLLQLEAEEHLELDFWK-------------SPSVPRQTVHVRVPFASIQDVKVFLESQGITYSIMIEDVQVLLDQEREEMLFNQQRE------------RGTN-FNFGAYHTLEEIYQEMDNLVAENPGLVSKVNIGSSFENRPMNVLKFSTGGD------KPAIWLDAGIHAREWVTQATALWTANKIASDYGT-----------DPAITSLLNTLDVFLLPVTNPDGYVFSQT--SNRMWRKTRSK-RSGS-FCVGVDPNRNWDAN-FGGPGASSNPCSDSYHGPSPNSEVEVKSIVDFIKS---HG-KVKAFITLHSYSQLLMFPYGYK-CAKPDDFNELDEVAQRAAQSLKRLHG---TSYKVG-PICSVIYQ--ASGGSIDWAYD-LGIKYSFAFELR---DTGYYGFLLPAKQILPTAEETWLGLKTIMEHVRDHPY--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48052-1", "uniprot_id": "CBPA2_HUMAN", "id": "P48052-1", "name": "Carboxypeptidase A2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMRLILFFGALFG-------------------HIYCLETFVGDQVLEIVPSN----EEQIKNLLQLEAQEHLQLDFWK-------------SPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRE------------RSGN-FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGK-----------DPSITSILDALDIFLLPVTNPDGYVFSQT--KNRMWRKTRSK-VSGS-LCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS---HG-KVKAFITLHSYSQLLMFPYGYK-CTKLDDFDELSEVAQKAAQSLRSLHG---TKYKVG-PICSVIYQ--ASGGSIDWSYD-YGIKYSFAFELR---DTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P8K8-1", "uniprot_id": "CBPA4_MOUSE", "id": "Q6P8K8-1", "name": "Carboxypeptidase A4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKWLLFFGALIGA------------------GICGRDKFFGDQVFRINVRN----GDEIRKLTELVNSDHLKLSVWK-------------SPSTFDRPVDILVPSVSLLPVKSFLKSQGLDYSVTIEDLQALLDNEDEEMQHNEGIE------------RSGD-FNYGAYHPLEAIYHEMDSIATDFPELVSRVKIGETFEKRPMYVLKFSTGGGK----KRPAIWLNAGIHAREWISQATAIWTARKIVTDYKK-----------DPAITSILKKVDIFLLPVANPDGYVYTQS--QNRLWRKTRSR-NPGS-RCVGADPNRNWNAS-FAGEGTSDNPCSEVYHGSHPNSEVEVKSVVDFIQK---HG-NFKCFIDLHSYSQLLMYPYGYT-VKKAPDAEELDDVARNAAQALASLSG---TKYRVG-PTCTTVYP--ASGSSVDWAYD-NGIKYAFTFELR---DTGYYGFLLPASQIIPTAEETWLGLKTIMEHVRDHLY--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI42-1", "uniprot_id": "CBPA4_HUMAN", "id": "Q9UI42-1", "name": "Carboxypeptidase A4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRWILFIGALIGS------------------SICGQEKFFGDQVLRINVRN----GDEISKLSQLVNSNNLKLNFWK-------------SPSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQE------------RSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGV----RRPAVWLNAGIHSREWISQATAIWTARKIVSDYQR-----------DPAITSILEKMDIFLLPVANPDGYVYTQT--QNRLWRKTRSR-NPGS-SCIGADPNRNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK---HG-NFKGFIDLHSYSQLLMYPYGYS-VKKAPDAEELDKVARLAAKALASVSG---TEYQVG-PTCTTVYP--ASGSSIDWAYD-NGIKFAFTFELR---DTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPZ8-1", "uniprot_id": "CBPA1_MOUSE", "id": "Q7TPZ8-1", "name": "Carboxypeptidase A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRLLVLSVLLA-------------------AVFGNENFVGHQVLRISATD----EAQVQKVRELEELEHLKLDFWR-------------DPARAGLPIDVRVPFPTIQSVKAFLEYHDISYEIMIEDVQSLLDEEKQQMSAFQARA------------LSTDAFNYATYHTLDEIYEFMDLLVTEHPQLVSKIQIGSTFEGRPINVLKFSTGGT-----NRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQ-----------EPTLTAILDNMDIFLEIVTNPDGFVYTHK--TNRMWRKTRSH-TEGS-LCVGVDPNRNWDAA-FGMPGASSNPCSETYRGKFPNSEVEVKSIVDFVTS---HG-NIKAFISIHSYSQLLLYPYGYT-SEPAPDKEELDQLAKSAVTALTSLHG---TKFKYG-SIIDTIYQ--ASGSTIDWTYS-QGIKYSFTFELR---DTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00731-1", "uniprot_id": "CBPA1_RAT", "id": "P00731-1", "name": "Carboxypeptidase A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRLLILSLLLE-------------------AVCGNENFVGHQVLRISAAD----EAQVQKVKELEDLEHLQLDFWR-------------DAARAGIPIDVRVPFPSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARA------------LSTDSFNYATYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGT-----NRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQ-----------DPTFTAVLDNMDIFLEIVTNPDGFAYTHK--TNRMWRKTRSH-TQGS-LCVGVDPNRNWDAG-FGMAGASSNPCSETYRGKFPNSEVEVKSIVDFVTS---HG-NIKAFISIHSYSQLLLYPYGYT-SEPAPDQAELDQLAKSAVTALTSLHG---TKFKYG-SIIDTIYQ--ASGSTIDWTYS-QGIKYSFTFELR---DTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15085-1", "uniprot_id": "CBPA1_HUMAN", "id": "P15085-1", "name": "Carboxypeptidase A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGLLVLSVLLG-------------------AVFGKEDFVGHQVLRISVAD----EAQVQKVKELEDLEHLQLDFWR-------------GPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRA------------RSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGS-----KRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQ-----------DAAFTAILDTLDIFLEIVTNPDGFAFTHS--TNRMWRKTRSH-TAGS-LCIGVDPNRNWDAG-FGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKD---HG-NIKAFISIHSYSQLLMYPYGYK-TEPVPDQDELDQLSKAAVTALASLYG---TKFNYG-SIIKAIYQ--ASGSTIDWTYS-QGIKYSFTFELR---DTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R4H4-1", "uniprot_id": "CBPA5_MOUSE", "id": "Q8R4H4-1", "name": "Carboxypeptidase A5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQGTQRGGLVPGLSPLDRRTLLFCNFILA-------------------VAWGQVNFTGDQVLRVLAKN----EKQLSLLRDLETQKPQKVDFWR-------------GPARPSLPVDMRVPFSELPSVKAYLKSHGLAYSIMIKDIQVLLDEERDAMAKSRRLE------------RSTNSFSYSSYHTLDEIYSWIDNFVAEHSNLVSKIHIGKSFENRSILVLKFSTGGP-----NRPAIWIDTGIHSREWITHATGIWISQKIVNAYGK-----------DHVLKRILNTMDIFIEIVTNPDGFAFTHS--MNRLWRKNKSS-QPGI-FCIGVDLNRNWKAG-FGGNGSNKNPCSETYRGPAPESEPEVAAIVDFITG---HG-NFKAMISIHSYSQMVMYPYGHS-LEPVPNHEELFNLAKDAVKALNKVHG---IQYIFG-SISTTLYS--ASGISVDWAYD-SGIKYAFSFELR---DTGQYGFLLPASQIVPTAEETWMALQTIMKHTLNHPY--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXQ8-1", "uniprot_id": "CBPA5_HUMAN", "id": "Q8WXQ8-1", "name": "Carboxypeptidase A5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQGTPGGGTRPGPSPVDRRTLLVFSFILA-------------------AALGQMNFTGDQVLRVLAKD----EKQLSLLGDLEGLKPQKVDFWR-------------GPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLE------------RSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGS-----RHPAIWIDTGIHSREWITHATGIWTANKIVSDYGK-----------DRVLTDILNAMDIFIELVTNPDGFAFTHS--MNRLWRKNKSI-RPGI-FCIGVDLNRNWKSG-FGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITA---HG-NFKALISIHSYSQMLMYPYGRL-LEPVSNQRELYDLAKDAVEALYKVHG---IEYIFG-SISTTLYV--ASGITVDWAYD-SGIKYAFSFELR---DTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U901-1", "uniprot_id": "CBPA6_MOUSE", "id": "Q5U901-1", "name": "Carboxypeptidase A6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNFLGNPRSHTAAFLPVCWLLLNILKPGH----------------CHSYDNRYAGDKVIRLIPKS----EEEALALKNIY--HQLKVDLWQPS---------SISYVSEGTITDVHISQNASRTLLAFLQETHIYYKVLIEDLQKAVENENSLQTQRNR--------------RSLSEYNYEVYHSLEDIQSWLHHLNQTQPGLVRVFSIGRSYEGRPLFIMQLGRKSRA----YKRAVWIDCGIHAREWIGPAFCQWFVREAILTYKT-----------DPAMKKMLNHLYFYIMPVFNVDGYHFSWT--HDRFWRKTRSR-DSKF-RCRGVDANRNWKVK-WCDEGASAHPCDDTYCGPFPESEPEVKAVANFLRK---HRKRIRAYLSFHAYAQMLLYPYSYK-YATIPNFSCVEFAAHKAVKALRSVHG---IRYRHG-PASQTLYV--SSGNSMDWAYK-NGIPYAFAFELR---DTGHFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M4P0-1", "uniprot_id": "F1M4P0_RAT", "id": "F1M4P0-1", "name": "Carboxypeptidase A6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKFLGKPRSLTAAFLPVCCLLLKILQPGH----------------CHSYDNRYAGHKVIRLIPKS----EEEALALKSVS--HQLKVDLWQPS---------SISYVSEGTITDVRVTQNASRTLLAILQETNIQYKVLIEDLQKAVENENSVHTQRNR--------------RSLSEYNYEVYHSLEDIQSWMHHLNQTQPGLVRVFPIGRSFEGRSLLIIQLGRKSQV----YKRAVWIDCGIHAREWIGPAFCQWFVKEAILTYKT-----------DPAMRKMLNHLYFYIMPVLNVDGYHFSWT--HDRFWRKTRSR-NSKF-HCRGVDANRNWKVK-WCDEGASADPCDDTYCGPFPESEPEVKAVANFLRK---HRKRIRAYLSFHAYAQMLLYPYSYK-HATIPNFSCVEFAAHKAVKALRSVHG---IRYRHG-PASQTLYV--SSGNSMDWAYK-NGIPYSFAFELR---DTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKNCP--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4T0-1", "uniprot_id": "CBPA6_HUMAN", "id": "Q8N4T0-1", "name": "Carboxypeptidase A6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKCLGKRRGQAAAFLPLCWLFLKILQPGH----------------SHLYNNRYAGDKVIRFIPKT----EEEAYALKKIS--YQLKVDLWQPS---------SISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNR--------------RSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSR-----LKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKS-----------DPAMRKMLNHLYFYIMPVFNVDGYHFSWT--NDRFWRKTRSR-NSRF-RCRGVDANRNWKVK-WCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRK---HRKHIRAYLSFHAYAQMLLYPYSYK-YATIPNFRCVESAAYKAVNALQSVYG---VRYRYG-PASTTLYV--SSGSSMDWAYK-NGIPYAFAFELR---DTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15089-1", "uniprot_id": "CBPA3_MOUSE", "id": "P15089-1", "name": "Mast cell carboxypeptidase A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRFFLLMAVIYTTLA---------------------IAPVHFDREKVFRVKLQN----EKHASVLKNLT--QSIELDFWYPD---------AIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKD------------------EIAGRHSYAKYNDWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGE----RK-AIFMDCGIHAREWISPAFCQWFVYQATKSYGK-----------NKIMTKLLDRMNFYVLPVFNVDGYIWSWT--QDRMWRKNRSR-NQNS-TCIGTDLNRNFDVS-WDSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRS---HLNSIKAYITFHSYSQMLLIPYGYT-FKLPPNHQDLLKVARIATDALSTRYE---TRYIYG-PIASTIYK--TSGSSLDWVYD-LGIKHTFAFELR---DKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKNTS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21961-1", "uniprot_id": "CBPA3_RAT", "id": "P21961-1", "name": "Mast cell carboxypeptidase A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LMGVIYSTLA---------------------IAPVQFDREKVFRVKLQD----EKQASILKNLT--QTIELDFWYPD---------AIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKE------------------EIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGE----RK-AIFMDCGIHAREWVSPAFCQWFVYQAAKSYGK-----------NKIMTKLLDRMNFYVLPVFNVDGYIWSWT--KDRMWRKNRSK-NPNS-TCIGTDLNRNFDVS-WDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRS---HLNSIKAYITFHSYSQMLLFPYGYT-IKLPPNHQDLLKVARIATDVLSSRYE---TRYIYG-PIASTIYK--TSGSSLDWAYD-LGIKHTFAFELR---DKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKHTS--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15088-1", "uniprot_id": "CBPA3_HUMAN", "id": "P15088-1", "name": "Mast cell carboxypeptidase A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLILPVGLIATTLA---------------------IAPVRFDREKVFRVKPQD----EKQADIIKDLA--KTNELDFWYPG---------ATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKE------------------DIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNER----RK-AIFTDCGIHAREWVSPAFCQWFVYQATKTYGR-----------NKIMTKLLDRMNFYILPVFNVDGYIWSWT--KNRMWRKNRSK-NQNS-KCIGTDLNRNFNAS-WNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRS---HLNEIKVYITFHSYSQMLLFPYGYT-SKLPPNHEDLAKVAKIGTDVLSTRYE---TRYIYG-PIESTIYP--ISGSSLDWAYD-LGIKHTFAFELR---DKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15086-1", "uniprot_id": "CBPB1_HUMAN", "id": "P15086-1", "name": "Carboxypeptidase B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLALLVLVTVALAS------------------AHHGGEHFEGEKVFRVNVED----ENHINIIRELA--STTQIDFWKPD---------SVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV------------------RATG-HSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK-AGQ----NKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGR-----------EIQVTELLDKLDFYVLPVLNIDGYIYTWT--KSRFWRKTRST-HTGS-SCIGTDPNRNFDAG-WCEIGASRNPCDETYCGPAAESEKETKALADFIRN---KLSSIKAYLTIHSYSQMMIYPYSYA-YKLGENNAELNALAKATVKELASLHG---TKYTYG-PGATTIYP--AAGGSDDWAYD-QGIRYSFTFELR---DTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19223-1", "uniprot_id": "CBPB1_RAT", "id": "P19223-1", "name": "Carboxypeptidase B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLLALVSVALA--------------------HASEEHFDGNRVYRVSVHG----EDHVNLIQELA--NTKEIDFWKPD---------SATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHT------------------RASG-HSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGK-TRP----NKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQ-----------EIHMKQLLDELDFYVLPVVNIDGYVYTWT--KDRMWRKTRST-MAGS-SCLGVRPNRNFNAG-WCEVGASRSPCSETYCGPAPESEKETKALADFIRN---NLSTIKAYLTIHSYSQMMLYPYSYD-YKLPENYEELNALVKGAAKELATLHG---TKYTYG-PGATTIYP--AAGGSDDWSYD-QGIKYSFTFELR---DTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QJN9-1", "uniprot_id": "F1QJN9_DANRE", "id": "F1QJN9-1", "name": "Carboxypeptidase B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLFLLLGLVAVALC----------------------EPITFVGDKVLQLKPIN----DEHVTIIRELG--EKIKLDFWKPR---------SADLVSIDMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQMDNRS------------------PTKG-HDYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTGS----NKPAVFMDCGFHAREWITHAFCQWFVNEAVSTYGS-----------DPDMTNLLDRMDFFVLPVFNIDGYEYTWN--RDRMWRKTRSK-NSGS-SCIGTDPNRNFNAG-WCTVGASSNPCSDTYCGSSPESEIESKNLANFIRT---NKSVIKAYLTVHSYSQLLLFPYSYK-YDLAAHHSELMSVSQGAIAALRSLYG---TKYTSG-PGAATIYP--AAGGSDDWAYD-LGVKYSYTFELR---DEGRYGFLLPESQIKPTCEETMLAVKYIANHVLNNLY--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JHH6-1", "uniprot_id": "CBPB2_MOUSE", "id": "Q9JHH6-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLHGLGILVAIILY--------------------EQHGFAFQSGQVLSALPRT----SRQVQLLQNLT--TTYEVVLWQPV---------TAEFIEKKKEVHFFVNASDVDSVKAHLNVSRIPFNVLMNNVEDLIEQQTFNDTVS----------------PRASASYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSFEKYPLYVLKVSGKEQR----IKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGK-----------ENLYTRLLRHVDFYIMPVMNVDGYDYTWK--KNRMWRKNRSA-HKNN-RCVGTDLNRNFASKHWCEKGASSSSCSETYCGLYPESEPEVKAVADFLRR---NIDHIKAYISMHSYSQQILFPYSYN-RSKSKDHEELSLVASEAVRAIESINKN--TRYTHG-SGSESLYL--APGGSDDWIYD-LGIKYSFTIELR---DTGRYGFLLPERYIKPTCAEALAAISKIVWHVIRNT---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQV9-1", "uniprot_id": "CBPB2_RAT", "id": "Q9EQV9-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLYGLGVLVAIILY--------------------EKHGLAFQSGHVLSALPRT----SRQVQLLQNLT--TTYEVVLWQPV---------TAEFIEKKKEVHFFVNASDVNSVKAYLNASRIPFNVLMNNVEDLIQQQTSNDTVS----------------PRASSSYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSYEKYPLYVLKVSGKEHR----VKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGK-----------ENTYTRLLRHVDFYIMPVMNVDGYDYTWK--KNRMWRKNRSV-HMNN-RCVGTDLNRNFASKHWCEKGASSFSCSETYCGLYPESEPEVKAVADFLRR---NINHIKAYISMHSYSQQILFPYSYN-RSKSKDHEELSLVASEAVRAIESINKN--TRYTHG-SGSESLYL--APGGSDDWIYD-LGIKYSFTIELR---DTGRYGFLLPERFIKPTCAEALAAVSKIAWHVIRNS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96IY4-1", "uniprot_id": "CBPB2_HUMAN", "id": "Q96IY4-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLCSLAVLVPIVLFC-------------------EQHVFAFQSGQVLAALPRT----SRQVQVLQNLT--TTYEIVLWQPV---------TADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVS----------------PRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQA----AKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGI-----------IGQYTNLLRLVDFYVMPVVNVDGYDYSWK--KNRMWRKNRSF-YANN-HCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR---NINQIKAYISMHSYSQHIVFPYSYT-RSKSKDHEELSLVASEAVRAIEKISKN--TRYTHG-HGSETLYL--APGGGDDWIYD-LGIKYSFTIELR---DTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IVL8-1", "uniprot_id": "CBPO_HUMAN", "id": "Q8IVL8-1", "name": "Carboxypeptidase O", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLET---------------------------YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGN----PKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKD-----------NSSIRKLLRNLDFYVLPVLNIDGYIYTWT--TDRLWRKSRSP-HNNG-TCFGTDLNRNFNAS-WCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES---KKDDILCFLTMHSYGQLILTPYGYT-KNKSSNHPEMIQVGQKAANALKAKYG---TNYRVG-SSADILYA--SSGSSRDWARD-IGIPFSYTFELR---DSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGR-VTSATMLLGLLVSCMSLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JLQ9-1", "uniprot_id": "CBPO_DANRE", "id": "B8JLQ9-1", "name": "Carboxypeptidase O", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQASITSILVVLTLVAQ----------------DRLAGGLEHKS---------------------------YDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTT----PKKAIWMDCGIHAREWIAPAFCQHFVKEVLGSYKT-----------DSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSPCHENS-TCSGTDLNRNFYAN-WGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGA---HQNHLLCYLTIHSYGQLILVPYGHP-NISAPNYDELMEVGLAAAKAIKAVHG---KSYKVG-SSPDVLYP--NSGSSRDFARL-IGIPYSFTFELR---DEGQHGFILPEDQIQPTCQEAYEGAMSIINYVHDKNFKNTAITVTATLWTTLMALWISTSHVF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL86-1", "uniprot_id": "CBPA1_DROME", "id": "Q9VL86-1", "name": "Zinc carboxypeptidase A 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLNKCLLFALLAIVASASVSAE-----------------------RVRYDNYRMYKVNSEN-----AKQLEVLKDLEGSSDSIMFLD-------------GVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRAT---------------TAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSE-------------VENIKELAENYTWYVLPHANPDGYVYTHT--TNRLWRKTR--TPYG--SCFGADPNRNWGFHWNEV-GASSSACSDTYAGPSAFSEIETLSLSKFIEG---LKGKVQLYLSLHAYSQYLLYPYGHT-SDLPDNVADFEKVFDASIAAVNKR-YG--TTYTGG-NIYDAIYP--AAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL87-1", "uniprot_id": "Q9VL87_DROME", "id": "Q9VL87-1", "name": "Peptidase M14 domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLLLLLSVNILIFCLAE-----------------------RQRFDNYKVYRVSPVK-----ANQLEGLRSLEANSEDALVLN-------------NLHLG--PTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRS---------------DDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHND---GRAEKQSIFLEAGMHAREWIGPATATYFANELLSSQ-------------QQEIMNLARSYVWYILPHANPDGYVYTHK--TNRMWRKTR--SPQDK-NCVGTDPNRNWDFHWREV-GASSDPCSESYAGPKAFSEPEVQTLSQFLKS---VPEPMFMFLSLHSFSQLLLYPYGHT-SALPENHRQLEQIFNTAVGAMKRR-YG--TRYTGG-NVYDAIYP--AAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGYKIE----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E9F9-1", "uniprot_id": "Q0E9F9_DROME", "id": "Q0E9F9-1", "name": "Zinc carboxypeptidase A 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGN------------KIINMPAARIGTQWLVILCVAMAASG-TNLDSGICPVAGDSGCRGNPPD-----QARYDNYRIYNVEFEN-----QEQIELFQKLEEQSDSLTFIG-------------HAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDA---------------SQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTS-N-----ANNKAIFIESGIHAREWISPAAATYIINQLLTSQ-------------DPKVQQLAQDYNWIIFPCVNPDGYKYTFE--HDRMWRKNR--QLFG--TCRGVDLNRNYPDHWNST-GSSSDPTRYDFAGPSAGSELETKRLIDFIRAN-AGKEQIKTYIALHSYSQMLMFPYGYT-KERVSNYDDLQEFGKKASAAIKAE-NG--RDYVSG-SLFETIYP--SSGGSMDWAHSEAGIPIAYTFELR-GPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCM8-1", "uniprot_id": "Q9VCM8_DROME", "id": "Q9VCM8-1", "name": "Zinc carboxypeptidase A 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYACQSALQENEMEIFYTDFKLRRIKMLPKGGTPKTWLLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELAS-----EEHVRLFQALEQASDSCSFMG-------------HARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVAPEDTKP---------------EEFDWKRYHPLESINAWLKKLAETHP-EVLLVELGVSAQGRPILGVQIAFDN-----ENRTTVFVESGIHAREWIAPATATYIIDQLVNSK-------------DSAVQALARSQRWYIFPTVNPDGYQYTFK--GDRMWRKNR--ALFG--ICRGVDLNRNFPFHWNVT-GASGDPCRYDYSGPSAASEVETQRMIEFIRHR-VESERIRTFISLHSYSQMIMFPYGHS-AERVDNYHDLTDIGKLAANKIKDV-SG--RIYKSG-SIYETIYP--SSGGSKDWAHGQLKIPITFSYELR-GPADSEDLFILSAKEIEPTAAEAFASIQTIVQEAGKRGYYQ------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLZ2-1", "uniprot_id": "Q9VLZ2_DROME", "id": "Q9VLZ2-1", "name": "Zinc carboxypeptidase A 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLWLLATLVALTSAGILKDSP----------------------KERYDNFRVYKLTIQN-----KIQLAAIEKIGELTKKYNIWK-------------EYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADS------------------ATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKA------GNPGIFIESNIHAREWITSASATWFINQLLTSE-------------DADVRSLADNYDWHIIPVFNVDGFEYSHK--KDRMWRKTRQPHA-TN-ACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTK---IQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYG--TVYQYG-STADVLYV--ATGTSVDWVFNELGKKIGYTIEYR---DKGRYGFILPPVQIIPNCEELMVGMLALIEKTKELGYL-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLZ1-1", "uniprot_id": "Q9VLZ1_DROME", "id": "Q9VLZ1-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALNSLPIVLALVVLAQGASFGQDE----------------------RLRYDNYSVYKVKFET-----QAQRSILRKLAEDRENFRLWH-------------EAKD---ELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRD----------------GTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKS------NNPGVLIESNIHAREWITSATATWLINEFLTST-------------DELVRDLAENHDWYIVPVLNVDGFVYTHE--KDRMWRKTRQPSE-IS-SCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVIS---IKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYG--TVYRYG-SAAGILYP--ASGATIDWAYNEQGVEISYTIEFR---DTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGYLGLKSAL-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRZ3-1", "uniprot_id": "Q9VRZ3_DROME", "id": "Q9VRZ3-1", "name": "Zinc carboxypeptidase A 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLKILLVVGLFGLARSVE----------------------QVRYDNYKVYNVRIDD-----LEQFKLLHTQ-ERSLKLSSWR-------------EARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRITS--------------------MEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKE------GNPAVFIESNIHAREWITSATITYFIDELLVPR-------------NPAVRDIAQNVDWYIIPVLNTDGFAYSHE--VERLWRKSRLPSDPTG-ECIGTDLNRNFDYLWMLT-GAESDPCSQLYAGPSPESDPEISQLTAYINNS-IPEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRR-YG--TVFTYG-SSATTLYE--VSGSGKEWAYAVKNIKIHYTIELR---DKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREIDIL-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS66-1", "uniprot_id": "Q9VS66_DROME", "id": "Q9VS66-1", "name": "Peptidase M14 domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKFSLGLLVLFLGATLVAAEQD-----------------------YEGYRIYEVIPST-----ADQADLLHQLSLQG--YDFIS-------------ETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAP----------ITGKGRLSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGD---GKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQ--------------FEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEE-GASSNPCADTYAGPTAFSEPETITVRDLMHS---LADRGIMYLTLHSYGNYLLYPWGWT-SDLPENWEDLDAVARTGAEAIENA-TG--TVYTYG-SSTNVLYI--AAGASDDYGYY-AGFNVSITMELPG---AGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIEMY---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS67-1", "uniprot_id": "Q9VS67_DROME", "id": "Q9VS67-1", "name": "Peptidase M14 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVVWVILALSCLSLSAGLQRTNK------------------------YEGYKIYEVSSEAR---SVAFSEALSELVKNASYYEVFS-------------ELN-AGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFP----------YNG--RLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGD---ARRNKNVILVDGGFHAREWISPAAATYLINQLVYN--------------LEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSSD---CIGTDPNRNFDFHWNEE-GASDDPCDNIYAGAKPFSEPEALVVGDLIHS---YVDRGQMYLTLHSYGSLILYPWGWT-AAVPDTEEDLHEVAAAGQSAIQEA-TG--TIYKIGPSATTINYA--ASGASDDYAFN-AGFPISFTMELP----FGGTGFDPPASDIDSIVKETWVGIAAMARKVIQKYPLA------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS64-1", "uniprot_id": "Q9VS64_DROME", "id": "Q9VS64-1", "name": "Peptidase M14 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQGIVCSLALCLVGLAGLGIAN---------------------NLAGYEGYTKYTVQHGD-----ENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPR--------RRTRRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVR---PRRVAYIQAATHGREWITTQTVLYLAYELLSNLR--------------AFTRVLQDVEIFLVPLVNPDGYEYTHT--TDRFWRKNRHRYAGHS--CSGVDINRNFGNH-WNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFN---RNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRG---TRYTTG-TSASILYE--ASGSLDDFAYGNLGIPLSYTLELP------GDEFHVPAHDIIHVCKETFAGFIEFIRHVSLY----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38836-1", "uniprot_id": "ECM14_YEAST", "id": "P38836-1", "name": "Inactive metallocarboxypeptidase ECM14", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLHMNSLWGCFLFVLLAVTGAVQG----------------------LQEDYSEYAVYRFTSDN------YSTLVRDVIAPLTDDYDVWT----------------RSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYD-----------------FFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPE-SNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGS-----------SKKETKYLDDLDFLVIPVFNPDGYAYTWS--HDRLWRKNRQRTHVPQ--CLGIDIDHSFGFQ---WEKAHTHACSEEYSGETPFEAWEASAWYKYINET-KGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYH-HRAHWAFQLKLR---DTGNHGFLLPPENIKPVGKETYAALKYFCDFLLDPEI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W477-1", "uniprot_id": "Q9W477_DROME", "id": "Q9W477-1", "name": "Peptidase M14 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRLPWKWAWLPLLLLITAKLEQVGGKTYLDWARTDSQLTRLPFFGGGVGHLLRYLHPLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGSSMAEREEDDEAAEKRQVLASPDAQFNEVVALFALTFVALIGSVFGQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQWLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFG--------SEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNPD-----NWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQ--TDRLWTKNRGYDSVSG--CYGVNLDRNFDYG-WDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSG---MREYLGAYVSLGGYGQAITYPWGDA-DYVTENQRNLKQTARRAVLALRRLNQ---AEYSSGTSYRQKLAR---PGNSADWVQDRIGPQLVFNMFLK---DQGRYGYLLPPHYIVESGEEVFEFLRIIAQQLQ------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : : : : . . :.*:*: . * **: : *:* *. * * ::.: : * . . * : : . .:.. : *:. . : * :: : . * : . ", "identical_positions": 16, "similar_positions": 42, "identity": "1.32%" }, { "cls_id": "homologset.agr.SGD:S000001175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A242-1", "uniprot_id": "D4A242_RAT", "id": "D4A242-1", "name": "Insulin-induced gene protein", "aln": "-----------MPRLHDHVWSYPSAGAARPYSLPRGMIAAALCPQ---------GP------GAPEPEPAPQGQREGTAA---FSTRPGSWHHDLVQRSLVLFSFGVVLALVLNLLQIQRNVTLFPDEVIAT----------------IFSSAWWVP--PCCGTAAAVVGLLYPCIDSHLGEPHK-------FKREWASVMRCIGVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSLSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLLCIFFSGGVTVGNIGRQLA-----------HSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08755-1", "uniprot_id": "INSI1_RAT", "id": "Q08755-1", "name": "Insulin-induced gene 1 protein", "aln": "-----------MPRLHDHVWSYPSAGAARPYSLPRGMIAAALCPQ---------GP------GAPEPEPAPRGQREGTAG---FSARPGSWHHDLVQRSLVLFSFGVVLALVLNLLQIQRNVTLFPDEVIAT----------------IFSSAWWVP--PCCGTAAAVVGLLYPCIDSHLGEPHK-------FKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGI3-1", "uniprot_id": "INSI1_MOUSE", "id": "Q8BGI3-1", "name": "Insulin-induced gene 1 protein", "aln": "-----------MPRLHDHVWNYPSAGAARPYSLPRGMIAAAACPQ---------GP------GVPEPEHAPRGQRAGTTG---CSARPGSWHHDLVQRSLVLFSFGVVLALVLNLLQIQRNVTLFPDEVIAT----------------IFSSAWWVP--PCCGTAAAVVGLLYPCIDSHLGEPHK-------FKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15503-1", "uniprot_id": "INSI1_HUMAN", "id": "O15503-1", "name": "Insulin-induced gene 1 protein", "aln": "-----------MPRLHDHFWSCSCAHSARRRGPPRASAAGLAAKVGEMINVSVSGPSLLAAHGAPDADPAPRGRSAAMSGPEPGSPYPNTWHHRLLQRSLVLFSVGVVLALVLNLLQIQRNVTLFPEEVIAT----------------IFSSAWWVP--PCCGTAAAVVGLLYPCIDSHLGEPHK-------FKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AV61-1", "uniprot_id": "INSI1_DANRE", "id": "Q8AV61-1", "name": "Insulin-induced gene 1 protein", "aln": "-----------MPRLEEHCWSCSCSTSVKTKDLS--SAGWIVCKT-------------------GEMMSIITSVLSHAYG-----SLHSLQSANLIRRGLVLFIVGVVLALVLNLLQIQRNVTLFPEEVLDT----------------LFSSAWWIP--LCCGTAAAVVGLLYPCLDHHLGEPHK-------FKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGFGLGLTTALLATLIAQLLVYNGIYQYTSPDFLYVRSWLPCIFFSGGVTVGNIGRQLAM----GSTEKIHND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91WG1-1", "uniprot_id": "INSI2_MOUSE", "id": "Q91WG1-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------------MAEGETES-----------------------PRPKKCGPYISS-------VTSQSVNVVIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVITS----------------IFSSAWWVP--PCCGTASAVIGLLYPCIDRHLGEPHK-------FKREWSSVMRCVAVFVGINHASAKVDFDNNFQFSLTLAALSVGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80UA9-1", "uniprot_id": "INSI2_RAT", "id": "Q80UA9-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------------MAEGETES-----------------------PRPKKRGPYISS-------VTSQSVNVVIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVITS----------------IFSSAWWVP--PCCGTASAVIGLLYPCIDRHLGEPHK-------FKREWSSVMRCVAVFVGINHASAKVDFDNNFQFSLTLAALSVGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5U4-1", "uniprot_id": "INSI2_HUMAN", "id": "Q9Y5U4-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------------MAEGETES-----------------------PGPKKCGPYISS-------VTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIAS----------------IFSSAWWVP--PCCGTASAVIGLLYPCIDRHLGEPHK-------FKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38837-1", "uniprot_id": "NSG1_YEAST", "id": "P38837-1", "name": "Protein NSG1", "aln": "MGKKKSKNQLNTGGVPNGVHNTKKEAALPPLGNKLGSASFTAINTLTKP---ALFSFYDDDITKNEGNVYDKALLSNASQLEMVPPSATARHERSLYAKIINTIAAFFILFIAGILFPMISECLFDNDQLAKGDIVSFLKHGIEIKNKIVAEPDMVPDWAVFGTEGVIFGSIVPFIDSFVRYQHQPKTRSSVYKNTLGSFIRCANTLLGLIFGIRKLEWSSSLQAAGAWSLLNIVLWLFFDGTLTVFFPGLVIGALSAFTCSQCFSQ----------LSLALYFIDFYFFGFLMFSKLGRYLFN-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: ...: :: .:* . ** : : . :.:.. :* ** ..:.* : * :* .: *: :*. .*.:** .::*: .. *::: ...* : : : *.: ** ** : : : *: . *::. . . : * : :: ::* * : ..::** * ", "identical_positions": 30, "similar_positions": 74, "identity": "9.46%" }, { "cls_id": "homologset.agr.SGD:S000001177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCP0-1", "uniprot_id": "KC1G1_HUMAN", "id": "Q9HCP0-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPSREK----------------------DERQRTTKPMAQRSA---HCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN-------------------------------------QVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTH8-1", "uniprot_id": "KC1G1_MOUSE", "id": "Q8BTH8-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK----------------------DDRQRTTKTMAQRNT---HCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRNQTTSSERRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62761-1", "uniprot_id": "KC1G1_RAT", "id": "Q62761-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK----------------------DDRQRTTKTMAQRNT---HCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIEALCENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN--------------------------------------QPRSLTAEWFVLAPL-SHPPAPT------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PRD4-1", "uniprot_id": "KC1G1_DANRE", "id": "Q5PRD4-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPREKE----------------------ADRPVRSSKVPQGRS---GHSRPSSSSASSGVLMVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKTLGSA-----DGLPQVFYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRNLFTELFDRKGYAFDYSYDWV------GRQIPTPVGTVHVDSGASAIT-RESHAHRDRPSQHQPLRN-------------------------------------QVVSSTNGELNADDPLAAHSNAPITAQAEVEVVDEA--------KCCCFFKRKRKKNTPRHK----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y6M4-1", "uniprot_id": "KC1G3_HUMAN", "id": "Q9Y6M4-1", "name": "Casein kinase I isoform gamma-3", "aln": "MENKKKDK----------------------DKSDDRMARPSGRSG---HNTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKMQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62763-1", "uniprot_id": "KC1G3_RAT", "id": "Q62763-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK----------------------DKSDDRMARPSGRSG---HSTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4X2-1", "uniprot_id": "KC1G3_MOUSE", "id": "Q8C4X2-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK----------------------DKSDDRMARPSGRSG---HSTRGTGSS-SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQ----------------------------------------VVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BVP5-1", "uniprot_id": "KC1G2_MOUSE", "id": "Q8BVP5-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG-------------------KGELEEGRRMSKTGTSRS---NHG-VRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWA------GKPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62762-1", "uniprot_id": "KC1G2_RAT", "id": "Q62762-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG-------------------KGELEEGRRMSKTGTNRS---NHG-VRNSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWA------GKPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78368-1", "uniprot_id": "KC1G2_HUMAN", "id": "P78368-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG-------------------KGETEEGRRMSKAGGGRS---SHG-IRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWA------GKPLPTPIGTVHTDLPSQPQL-RDKTQPHSKNQ---------------------------------------------ALNSTNGELNADDPTAGHSNAPITAPAEVEVADET--------KCCCFFKRRKRKSLQRHK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIW9-1", "uniprot_id": "A0A8M2BIW9_DANRE", "id": "A0A8M2BIW9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDFDKRGGGGG----------------KGEAEDGKRMSKTGGSRT---GHGGSRGSGNNTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGNA-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRDVKPENFLVGRPGTKRQHTIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFP-EMATYLRYVRRLDFFERPDYEYLRKLFTDLFDRNGYVFDYEYDWV------GKPLPTPIGPMPSDTPLQPSN-RDKAQPQTKNQSPEPKGSESQPT-----------PVTNRELLGSHLTADRLGGSVQVMSSTNGEVNTDDPTAGHSNAPITAPAEVEVADDT--------KCCCFFKRRKRKALQRHK----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHL4-1", "uniprot_id": "A0A0B4KHL4_DROME", "id": "A0A0B4KHL4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQRRERQASGGGPQTTTAG-------PSAGNVANATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWT------GKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVP--------------KPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDET--------KCCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSNSRDSVLNNPSQDYIQQATSQHTLRYPPSASMLTPTPTTNTPTLPL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23291-1", "uniprot_id": "KC11_YEAST", "id": "P23291-1", "name": "Casein kinase I homolog 1", "aln": "MSMPIASTTLAVNNLTNINGNANFNVQANKQLHHQAVDSPARSSMTATTAANSNSNSSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGT-----PNIPYAYYFGQEG-LHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDWMKLNDGRGWDLNINKKPNLHGYGHPNPPNEKSRKHRNKQLQMQQLQMQQLQQ-----------------------------QQQQQQYAQKTEADMRNSQYKPKLDPTSYEAYQHQTQQK--------YLQEQQKRQQQQKLQEQQLQEQQLQQQQQQQQQLRATGQPPSQPQ-----AQTQSQQFGARYQPQQQPSAALRTPEQHPNDDNSSLAASHKGFFQKLGCC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . . :** ::::***** *.** * *.*: .. ****:** *:.****: **: ** *. .:* :::* * :* :*::*** ******: * *.*::***: :* *:: :* :*:: *****:**:***:** . : **:****:**:* * .*::******:***:***********:*:*******:*****:*:***** ******** . *::*:***:.** * : *.:. * :: **. ** *.* * ***: * *: .::: * : :** * : . . .. : : . * . * ", "identical_positions": 152, "similar_positions": 90, "identity": "25.94%" }, { "cls_id": "homologset.agr.SGD:S000001179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64602-1", "uniprot_id": "AADAT_RAT", "id": "Q64602-1", "name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial", "aln": "---------------MNYSRFLTATSLARKTSPIRATVEIMSRAPKDIISLAPGSPNPKVFPFKSAVFTVENG-----------------STIRFEGEMFQRALQYSSSYGIPELLSWLKQLQIKLHNPPTVNYSPNEGQMDLCITSGCQDGLCKVFEMLINPGDTVLVNEPLYSGALFAMKPLGCNFISVPS------DDCGIIPEGLKKVLSQWKPEDSKDPTKRTPKFLYTIPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFLQFT------------------------KPWEPTFLSMDVDGRVIRADSLSKVISSGLRVGFITGPKSLIQRIVLHTQISSLHPCTLSQLMISELLYQWGE--------------EGFLAHVDRAIDFYKNQRDF---ILAAADKWLRGLAEWHVPKAGMFLWIKVNG--------ISDAKKLIEEKAIEREILLVPGNSFFVDN---SAPSSFFRASFSQVTPA-QMDLVFQRLAQLIKDVS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVM8-1", "uniprot_id": "AADAT_MOUSE", "id": "Q9WVM8-1", "name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial", "aln": "---------------MNYSRFLTATSLARKPSPIRTTADILSKAPKTLISLAPGSPNPSMFPFKSAAFTVENG-----------------STIRFEDDLIKRALQYSPSYGIPELLSWLKQFQVKLHNPPTVNYPPNQGQMDLCITSGCQDGLCKAFEMLINPGDTILVNEPLFPGTLYAMKPLGCNIINVPS------DEHGIIPEGLKKILSQWKPEDSKDPTKKTPKFLYTVPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFLQFS------------------------KPWEPTFLSMDVDGRVIRADTFSKTVSSGLRVGFMTGPKTLIQNIVLHTQVSSVHACTLSQLMILQLLHQWGE--------------EGFLAHIDRTIDFYKNQRDS---ILAAADKWLRGLAEWHVPKAGMFLWIKVKG--------ISDTKQLIEEKAIEREVLLVPGNGFFIDG---SAPTSFFRASFSLATPA-QMDTAFQRLAQLIKESL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5Z0-1", "uniprot_id": "AADAT_HUMAN", "id": "Q8N5Z0-1", "name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial", "aln": "---------------MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENG-----------------KTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVAS------DESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFN------------------------KFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGE--------------EGFMAHVDRVIDFYSNQKDA---ILAAADKWLTGLAEWHVPAAGMFLWIKVKG--------INDVKELIEEKAVKMGVLMLPGNAFYVDS---SAPSPYLRASFSSASPE-QMDVAFQVLAQLIKESL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38840-1", "uniprot_id": "ARO9_YEAST", "id": "P38840-1", "name": "Aromatic amino acid aminotransferase 2", "aln": "MTAGSAPPVDYTSLKKNFQPFLSRRVENRSLKSFWDASDIS----DDVIELAGGMPNERFFPIESMDLKISKVPFNDNPKWHNSFTTAHLDLGSPSELPIARSFQYAETKGLPPLLHFVKDFVSRINRP--AFSDETESNWDVILSGGSNDSMFKVFETICDESTTVMIEEFTFTPAMSNVEATGAKVIPIKMNLTFDRESQGIDVEYLTQLLDNWSTGPYKDLNK--PRVLYTIATGQNPTGMSVPQWKREKIYQLAQRHDFLIVEDDPYGYLYFPSYNPQEPLENPYHSSDLTTERYLNDFLMKSFLTLDTDARVIRLETFSKIFAPGLRLSFIVANKFLLQKILDLADITTRAPSGTSQAIVYSTIKAMAESNLSSSLSMKEAMFEGWIRWIMQIASKYNHRKNLTLKALYETESYQAGQFTVMEPSAGMFIIIKINWGNFDRPDDLPQQMDILDKFLLKNGVKVVLGYKMAVCPNYSKQNSDFLRLTIAYARDDDQLIEASKRIGSGIKEFFDNYKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *:: *. ..: :* . :*.** * ** .**::: :.:.: . : *::**: : *:* ** ::*:: :::.* .:.: *: ::.*.::.: *.** : : . .::::* :. :: :.. *.:.* : :. ** : * .:*..*.. *: * *:.***:..*:**** *:. ::::**:**:::****:***** :* * . :**::*.*.**** :::** .:.***:.*:.. * *::.:: :::: .. .* :: . : .* **:: : : . *.:::: * ::.: * * ****: **:: : : .:::: :: : :: * : : . : ::* ::: . *: . : :.. **: ", "identical_positions": 96, "similar_positions": 176, "identity": "18.43%" }, { "cls_id": "homologset.agr.SGD:S000001182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C138-1", "uniprot_id": "ADTRP_MOUSE", "id": "Q8C138-1", "name": "Androgen-dependent TFPI-regulating protein", "aln": "----------------------------------MTKTT------TCVYHFLVLNWYIFLNYHIPQIGRNEEKLREFHDGGRSKYLTLLN-LLLQAIFFGVACLDDVLKRVI--GRKDIK-----FVTSFRDLLFTTMAFPISTFVFLVFWTLFHYDRSLVYP---KGLDDFFPAWVNHAMHTSIFPFSLFETILR---PHNYPSKKLGLTLLGAFNFAYIIRILWRYVQTG--NWVYPVFDSLSPLGIIIFFSAAYILVAGIYLFGEKINHWKWGAIAKPQMKKN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M828-1", "uniprot_id": "ADTRP_RAT", "id": "Q5M828-1", "name": "Androgen-dependent TFPI-regulating protein", "aln": "----------------------------------MTKTT------TCLYHFVVLNWYIFLNYYIPQIGKDEEKLKEFHDGGRSKYLTLLN-LLLQAVFFGVACLDDVLKRVI--GRKDIK-----FITYFRDLLFTTLAFPLSTFVFLVFWSLFHYDRSLVYP---KGLDDFFPAWVNHAMHTSIFPFSLAETVLR---PHNYPSKKLGLSLLGACNFAYIIRILWRYVQTG--NWVYPVFASLSPLGIILFFSASYILSASLYLFGEKINHWKWGATVKPRMKKN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96IZ2-1", "uniprot_id": "ADTRP_HUMAN", "id": "Q96IZ2-1", "name": "Androgen-dependent TFPI-regulating protein", "aln": "----------------------------------MTKTS------TCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLN-LLLQTIFYGVTCLDDVLKRTK--GGKDIK-----FLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYP---KVLDTVIPVWLNHAMHTFIFPITLAEVVLR---PHSYPSKKTGLTLLAAASIAYISRILWLYFETG--TWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N590-1", "uniprot_id": "A0A8M1N590_DANRE", "id": "A0A8M1N590-1", "name": "", "aln": "----------------------------------MAASTRLGPKVLLLVHLGVFSWYLFTIWSNCSLQTADRHPGLRSYGGRWKYLTFIN-LVMHAVFFGLCVLVDAVHSAV--SVNQSRSGTPLNLSRARDFYFTVLAFPVGTFVFVSFWTLYTYDRELVYP---KLLDEIIPIWLNHAMHTVIMPLLLLQMFLQ---NHRYPSRTAGIFSLAVFVALYLSWVLWVHHASG--IWVYPIMAHLSPVGLCVFLGGASLSMAPLYLLGEKLSLMMWSSTGNQKKKKK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D8B1-2", "uniprot_id": "AIG1_MOUSE", "id": "Q9D8B1-2", "name": "Androgen-induced gene 1 protein", "aln": "----------------------------------MALVP----------CQVLRVAILLSYCSILCNYKAIEMPSHQTYGGSWKFLTFID-LVIQAVFFGICVLTDLSSLLTRGSGNQEQERQLRKLISLRDWTLAVLAFPVGVFVVAVFWTIYAYDREMIYP---RLLDNFIPGWLNHGMHTTVLPFILIEMRTS---HHQYPSRSSGLAAICTFSVGYILWVCWIHHVTG--MWVYPFLEHIGSGARIIFFGSTTILMNFLYLLGEVLNSYIWDTQRSIEEEKEKPKLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVV5-2", "uniprot_id": "AIG1_HUMAN", "id": "Q9NVV5-2", "name": "Androgen-induced gene 1 protein", "aln": "----------------------------------MALVP----------CQVLRMAILLSYCSILCNYKAIEMPSHQTYGGSWKFLTFID-LVIQAVFFGICVLTDLSSLLTRGSGNQEQERQLKKLISLRDWMLAVLAFPVGVFVVAVFWIIYAYDREMIYP---KLLDNFIPGWLNHGMHTTVLPFILIEMRTS---HHQYPSRSSGLTAICTFSVGYILWVCWVHHVTG--MWVYPFLEHIGPGARIIFFGSTTILMNFLYLLGEVLNNYIWDTQKSMEEEKEKPKLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9S4-1", "uniprot_id": "A0AB32T9S4_DANRE", "id": "A0AB32T9S4-1", "name": "", "aln": "----------------------------------MQLCDR------VSFLELFFTRPVPRRRSQLLSVSQVHRHMRRGTGQTDNSGKVIHKEVIQAVFFGVCVLTDLSSLLTKGSASMEQERQLRKLIGLRDWMMAVLAFPVGVFVVTMFWTLYLYDRDLIYP---RLLDNFIPQWLNHGMHTTVLPFIIIEMRTT---HHRYPSRPCGLLAVCAFAVGYVVWMCWVHSMTG--VWVYPLLEHIGPTARILFFFCLMALINVYYVLGEILNNYIWDSSKCILES-DKTKTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPM9-1", "uniprot_id": "Q9VPM9_DROME", "id": "Q9VPM9-1", "name": "Androgen-induced gene 1 protein", "aln": "MGKSKKQVREFNAAKEAVEATKAQLNTCNDAYTSGAFKYLRFLVHLLAAAQFSYGIYFHYFRVHWPTDLLDEDELKARWGGKFKYLTFLD-VILQAIYHSLALLNDLFGDNN------VSGDSKSMLRSVRDYVFAAFAFPVAHNVCLSFWVIYVWDRELIFP---SALDAIFPSWLNHVVHTNVALLAIMDLFTC---FRRYPSRLAGITGNVSFILLYIIWLHIVRYFSG--EWVYPILEVLPAYLRYVFLALLVGFNLVCYLLGEFANNVVWGPEFKLLNQQKLKQG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPN0-1", "uniprot_id": "Q9VPN0_DROME", "id": "Q9VPN0-1", "name": "Androgen-induced gene 1 protein", "aln": "----MASVRG------------------NSVYQ-GVYGALRTLLHLTAVVQFGYGIYYDYNYVQFPTSEP-EMRIHHPWGGKFKYLTFLD-AIIQALYYIVSLVNDFVGTNE------LTPKKPPAVRRFKDWLMATLAFPVAINVGVTFWTLYAIDRELVFP---KVLDPVFPSWLNHVLHTNIVVFIILELFIS---YRSYPKRSQGLAGLAIFMGAYLVWIHVVKHYSG--VWVYPVLEVLQLPQRILFFAAVVGFTLSLYLLGEFLNNTVWAKEVKLAKRKSN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTI1-1", "uniprot_id": "Q9VTI1_DROME", "id": "Q9VTI1-1", "name": "Androgen-induced gene 1 protein", "aln": "------------------------------MERLNLSNRARLFFHLSATVHLGYAIYFDCRYAQLP-QVAVTLRLEPPIGGKFKYMTFLC-GLLQLGYYTLALTFDLLR--------------LRSLRKLRDYIFATFAVPLALTVGLTFWTLFAIDREVIYP---VLLDLVYPNWLNHTMHTFVVIYAFVELGIT---RHQYPKRSRGFTGLGAFMLGYLVWIHIVWFRTD--IWVYPFLGGIAWQLRVIFFVLIMVLGFIYYLFGERVNNVLWQRSTGVHRWIDSH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38842-1", "uniprot_id": "YHU0_YEAST", "id": "P38842-1", "name": "UPF0641 membrane protein YHR140W", "aln": "----------------------------------MMSCLVP-----TRFTLTLNTACLLTSTWGFVRATSVVLPPSLSKAGHKQFLTIIS-IIATIINNAVNISNYYIQRNN-----KMNLETKKKSDFISRHVTLPVSLVLESIVATVYWPLRLFFVNLIMHGVESTAKTPFPMTVDMAIHLYPILYLLADHYLSGSGTKFKLSNKHAWLIVTSLAFSYFQYLAFLIDAGQGQAYPYPFLDVNEPYKSIIFVVVATITWAYYVFYQKFPPKYIKKSAKKGDKN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ..: : : .:. : * :* : .:: . * :: :* : : : .. . *. : : **.: *. . : ", "identical_positions": 8, "similar_positions": 34, "identity": "2.75%" }, { "cls_id": "homologset.agr.SGD:S000001183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83883-1", "uniprot_id": "RL36A_RAT", "id": "P83883-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83882-1", "uniprot_id": "RL36A_MOUSE", "id": "P83882-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83881-1", "uniprot_id": "RL36A_HUMAN", "id": "P83881-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q969Q0-1", "uniprot_id": "RL36L_HUMAN", "id": "Q969Q0-1", "name": "Ribosomal protein eL42-like", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGRRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R7E5-1", "uniprot_id": "M0R7E5_RAT", "id": "M0R7E5-1", "name": "", "aln": "MWRSLVAHVTATPYVVNVPKTRQTFCK--KCGKHQPHKVTQYKMGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKSTKKNVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKCQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0A6YW33-1", "uniprot_id": "A0A0A6YW33_MOUSE", "id": "A0A0A6YW33-1", "name": "", "aln": "--------------MVNVPKTRQTFCK--KCGKHQSHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLESVEPNCRSKRMLARKRCEHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61485-1", "uniprot_id": "RL36A_DANRE", "id": "P61485-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTYCK--KCKKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT7-1", "uniprot_id": "Q9VLT7_DROME", "id": "Q9VLT7-1", "name": "", "aln": "--------------MVNVPKQRRTFCK--KCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTE--CKYRKQTPLKRCKHFELGGDKKRKGQMIQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX28-1", "uniprot_id": "RL44B_YEAST", "id": "P0CX28-1", "name": "Large ribosomal subunit protein eL42B", "aln": "--------------MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***** *:*:** .* * ******* .* ***:*******.*:******:*:****:*** ***:*..: *: : . ***:******:**:* * :**", "identical_positions": 64, "similar_positions": 22, "identity": "52.46%" }, { "cls_id": "homologset.agr.SGD:S000001185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53803-1", "uniprot_id": "RPAB4_HUMAN", "id": "P53803-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "aln": "----------------------------MDTQKD-VQPPKQQPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LDU3-1", "uniprot_id": "A0ABK0LDU3_RAT", "id": "A0ABK0LDU3-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "aln": "----------------------------MDTQKD-VQPPKQQPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZL46-1", "uniprot_id": "A0A8I5ZL46_RAT", "id": "A0A8I5ZL46-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "aln": "MEVKKSFRGNGVCVLRGGTLSGVAEARTVDTQKD-VQPSKQQPMINICGECHTENEIKSRDPIRCKECGYRIMYKKRTKRLMVFDARWNRGVEERLHTFASLMFLFNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63871-1", "uniprot_id": "RPAB4_MOUSE", "id": "Q63871-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "aln": "----------------------------MDAQKD-VQPPKQQPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40422-1", "uniprot_id": "RPAB4_YEAST", "id": "P40422-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "aln": "-----------------MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .. .: .: **.** :: .:. *.:**::**:**: * *****: *:** ", "identical_positions": 21, "similar_positions": 22, "identity": "19.44%" }, { "cls_id": "homologset.agr.SGD:S000001187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2D6-1", "uniprot_id": "DCTD_MOUSE", "id": "Q8K2D6-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSDISCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPN---GCSDDLLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSADVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSR-PSQKPQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9G0-1", "uniprot_id": "DCTD_RAT", "id": "Q5M9G0-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSDISCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPN---GCSDDLLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSADVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSR-PSQKPQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32321-1", "uniprot_id": "DCTD_HUMAN", "id": "P32321-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSEVSCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPN---GCSDDVLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSTDVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSR-PSQKLQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWA2-1", "uniprot_id": "DCTD_DROME", "id": "Q9VWA2-1", "name": "Probable deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MAEVSAQDLISQLSKSPESHKRKEYL----------------------------------------HWDDYFMATSLLSAKRSKDPVTQVGACIVDSQNRIVAIGYNGFPR---NCSDDVFPWSKAKKGSQEFDPLEDKKMYVVHAEANAILNSNGMSLSG-TRLYTTLFPCNECAKLIIQVGISQVLYLSDKYADKPTYRASKRMLDAVGVEYKRHIPQKKTITIDFDTFPEEDPNASLGLNELHL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06773-1", "uniprot_id": "DCTD_YEAST", "id": "P06773-1", "name": "Deoxycytidylate deaminase", "aln": "MLIGVSGTKFCGCEDVINMLVDHFHFELLNHLDNPEEILDYATKNYTKNSVIFLEKLSLLEKLEKRPFFVHLSIDAPVTTRVALYRKTTQAESLSLEQIIQAIDQHDFQPEGIKLREKSHLRFKIVNEDRRGRRQSLINNITTQLKILDDKEKQMAPLMRPSWDSYFMKLATLAASRSNCMKRRVG-CVIVRECRVIATGYNGTPRHLTNCFNGGCPRCNDGDS------RNLHTCLCLHAEENALLEAGRDRVGQNATLYCDTCPCLTCSVKIVQTGISEVVYSQSYRMDEE----SFKVLKNAGITVRQFSFTEEPRIVMI-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :...:* * .*** : *:*.**: :** *:: : :::. **** *. .* :. * . .. : : *** **::: . : :* ** *: *:*.**.:*:: .. *. : ::. .*: ::. . : : ", "identical_positions": 35, "similar_positions": 58, "identity": "10.23%" }, { "cls_id": "homologset.agr.SGD:S000001191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921Y2-1", "uniprot_id": "IMP3_MOUSE", "id": "Q921Y2-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP3", "aln": "MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREEYTRYNQLSRAVRELARRLRDLPERDPFRVRASAALLDKLYAMGLVPTRGSL-ELCDSVSASSFCRRRLPTLLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDFDLDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV31-1", "uniprot_id": "IMP3_HUMAN", "id": "Q9NV31-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP3", "aln": "MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREDYTRYNQLSRAVRELARRLRDLPERDQFRVRASAALLDKLYALGLVPTRGSL-ELCDFVTASSFCRRRLPTVLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDFDLEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32899-1", "uniprot_id": "IMP3_YEAST", "id": "P32899-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP3", "aln": "MVRKLKHHEQKLLKKVDFLEWKQ-DQGHRDTQVMRTYHIQNREDYHKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVTVSAICRRRLPVIMHRLKMAETIQDAVKFIEQGHVRVGPNLINDPAYLVTRNMEDYVTWVDNSKIKKTLLRYRNQIDDFDFS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.*******:****:*: *:. :: :*:* *::*.**:* :**::. :*.**.:* ** * ** : . *******:*::.*:..: :* : *:.*::******.:: :*:**: :* ** *:*********:::.***:****.***:*****.****: :*.*.:: ****:. ", "identical_positions": 96, "similar_positions": 62, "identity": "51.89%" }, { "cls_id": "homologset.agr.SGD:S000001198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZU57-1", "uniprot_id": "A0A8I5ZU57_RAT", "id": "A0A8I5ZU57-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS------------PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLF-------INH-HPPGQ---------------------TSRKYSSCST--------------------------------------------------------------------------IFLDDSTVSQPNLKYTIKCVALAIYYHIKNRD-----------------------------------------------------------------------PDGRMLLDIFDENLHPLSKSE--------------------VPPDYDKHNPEQ----------------------------------------------------------------------------------------KQIYRFVRTLFSAAQLTAECAIVTLVYLERLLT--YAEIDICPANWKRIVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFN-----------------INVPSSVYAKYYFDLRSLAEANSLSFPLEPLSRERAHKLEAISRLCEDKY---KDLRKPMRKRSASADNLI--LPRWSPAIIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGU5-1", "uniprot_id": "CCNY_MOUSE", "id": "Q8BGU5-1", "name": "Cyclin-Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS------------PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLF-------INH-HPPGQ---------------------TSRKYSSCST--------------------------------------------------------------------------IFLDDSTVSQPNLKYTIKCVALAIYYHIKNRD-----------------------------------------------------------------------PDGRMLLDIFDENLHPLSKSE--------------------VPPDYDKHNPEQ----------------------------------------------------------------------------------------KQIYRFVRTLFSAAQLTAECAIVTLVYLERLLT--YAEIDICPANWKRIVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFN-----------------INVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKY---KDLRKPMRKRSASADNLI--LPRWSPAIIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND76-1", "uniprot_id": "CCNY_HUMAN", "id": "Q8ND76-1", "name": "Cyclin-Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS------------PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLF-------INH-HPPGQ---------------------IARKYSSCST--------------------------------------------------------------------------IFLDDSTVSQPNLKYTIKCVALAIYYHIKNRD-----------------------------------------------------------------------PDGRMLLDIFDENLHPLSKSE--------------------VPPDYDKHNPEQ----------------------------------------------------------------------------------------KQIYRFVRTLFSAAQLTAECAIVTLVYLERLLT--YAEIDICPANWKRIVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFN-----------------INVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKY---KDLRRSARKRSASADNLT--LPRWSPAIIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y7Z8-1", "uniprot_id": "A0A286Y7Z8_DANRE", "id": "A0A286Y7Z8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNSTSCCVSSS------------PKLRRN---------------------AHSRLEPYR---PEPELSREDTGCN------------------LQHISDRENIDELNMEYNPSDHPRASTIFLSKSQTD---VREKRKSLY-------VNHQHPSGP---------------------MRRKYSSCST--------------------------------------------------------------------------IFLDDSTVSQPNLKYTIKCVALAIYYHIKNRN-----------------------------------------------------------------------VDGRMLLDIFDEKLHPLSKSE--------------------VPSDYDKHDPEQ----------------------------------------------------------------------------------------KQIYRFVRTLFSAAQLTAECAIVTLVYLERLLT--YAEIDICPANWKRIVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFN-----------------INVPSSVYAKYYFDLRSLSEANNLSFPLEPLSRDKAQKLEAISRLCDDKY---KDLRKAAKKRSVSADNLS--VVRWSPAIIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08CI4-1", "uniprot_id": "CCYL1_DANRE", "id": "Q08CI4-1", "name": "Cyclin-Y-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTVSCCVSPSGS----------PKLPR----------------------QVERLEDYQ---NNTDIS-DDTGPY------------------LQHISDREVPDDLALESNPSDHARASTIFLSKSQTD---VRDRRKSNH-------INH-VSPGL---------------------LSKKYSSCST--------------------------------------------------------------------------IFIDDSTVSQPNLKSTIKCVTLAIYYHIKNRD-----------------------------------------------------------------------SDR--SLDIFDEKMHPLSREQ--------------------VPDDYSRTDPEH----------------------------------------------------------------------------------------KLIYRFVRTLFSAAQLTAECAIVTLVYLERLLT--YAELDICPSNWKRIVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNEMERHFLELLQFN-----------------INVPASVYAKYYFDLRSLADDNNLSFPLEPLSNERAQKLEAISRLCEDKY---KDLSRVAMRRSFSADNLV--GIRRSNAVLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKF0-1", "uniprot_id": "Q9VKF0_DROME", "id": "Q9VKF0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNKNSCCAYSS------------PQSDRKSKDMPPVFEERIIQLGHPPHTSQHQLDGHHGSASAVHLHHHHHGHNQQQNQQGGGGDNYENQQNLQHISERE---ALEGEEDPSVDPTAATMFLERSKVENGGMTRKRSQQQ-------IAQQAGSGGGGGGGGGGGSTPGGNSCGGGGGMKKSSSCST--------------------------------------------------------------------------IYLDDSTVSQPNLKNTVKCVSLAIYYHIKNRQ-----------------------------------------------------------------------SDRR--LDIFDEKLHPLTHDQ--------------------VPDNYDTHNPEH----------------------------------------------------------------------------------------RQIYKFVRTLFNAAQLTAECAIITLVYLERLLT--YAELDVGPCNWKRMVLGAILLASKVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFN-----------------INVPSSVYAKYYFDLRTLAEANELNFPTEPLSKERAQKLEAMSRVMQDKVT--AEALKNGIKKWSSMDNISQGGPRRSVAILS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38851-1", "uniprot_id": "LAM1_YEAST", "id": "P38851-1", "name": "Membrane-anchored lipid-binding protein LAM1", "aln": "MHEHKAELRLITVALNEASTDSPSFRASVNYFHTRMESLSSWMHSTVDYVENTYKPSFQDFQRIKETLFSQLLPSPILLSNGFVSNQPYTPLLVRDFTRDVSDLSNTVMKIILGDENSQYTAALSALSSDAINPYFNKRKTFEYYQRKYDSFLTDFLAATNDGNTLIPQNLQNETFKLVDIKHKYIEASLDLTEAISLMKVNLDKFLIETIDIVRKNNVITTKDTKDVIDITPELTETLKDWTDWIESNLQTLQALSSKLSEAKYAILKLSLARMKPSRLIQDYDLKSIQNLKFNLPKSISNGNNSEEKGLSGWLYMKTTVGHDPKRVVWVRRWCFLQNNVFGVFSLSPSKTYVEETDKFGILWITVEYLPKEPRNFCFKLRIQN---------PNCKTEEENTYIDIILQAESIDELKSWINTLTSHKRIALSIKEENDPRYQLARKKIEPQFFEFASSSSTSTDKLLTSFSSKTLTLVEELKKNYMSEDDIYSIIDNKAYHLRVISTPIATQLTHLALFSTFLSVSNYYPCATQANTWGTANWNDLSYLVNPLKGSSVHKPATVSNSSRFSVSYPDYYPYSLKVDDIQFRSIFFSVNHDFLQVPKELVLLRYSSVWCPNNKQKFASMAFVTLNHIYVYLNISGFSYLRRIDLLDIDSIEYDKSPKHVSSRMLHMQRGDGLRFNMSVFFTDRRAVASKLQFLIENKAMHIPKGEKEVLEIFQELDEEIENEKKIIKDNLSESEHYSKDYDYLLKSTYDHHFENTNETPMELMSRKLRLEREAWCYFQDNFKVGSKTLFHVLFGDKSQVFPSSLFLCKKGSNLNNNSYWERIRRAKEDASCQFELCRKLQFQLNRTSNFIKDLLWLKDDNDNFKLVLQQRVTKIKQGYYFEVEEGPIIVKFPLCHPLLLRVRFIIAECITSQGESLKKCDLAILYDFNYVESIDKLNTKVEKLWLFERIHLNWALRYCKLEHSEINRKTREYLKKFNDREKMSDVIKLCGFLGVLPKERIENDEKAGDFMQPVYINYDFLSLSKIFTKLTVFYLSSVIIKTMKVLLAMVMVIFKCFSKVNKTLYYCLLISAVTNLFFVGKSIHSYFSVKSAETLFQNYANGDQRGLQIMHRSLTVPDLNLLTRKMMDNDQENPVFKRFDEDKNAYQYKGTRQEIAIKRNQVLTELKILQNTEKELVQGSYRKFIITERDKCITTQNEIFDLWINDTKLQDYCMACFAEYNRLSAIPV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : .. *: * . : : . . . :: *: * .* . : .:: . *. : :.. : . : .*:* : : *:* ** * .. .:::. ** . *:**:* . : ..: : *. : . .*:: *: : . : :: : :: * *:: * * : .:** :. :.: . * . : . **.::::: :. :* *: ** : * * : * ..::: .* *..:: .: * . . : : : : .::: ", "identical_positions": 41, "similar_positions": 115, "identity": "3.31%" }, { "cls_id": "homologset.agr.SGD:S000001199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F786-1", "uniprot_id": "B4F786_RAT", "id": "B4F786-1", "name": "CD2 antigen cytoplasmic tail-binding protein 2", "aln": "MPKRKVTFQGVGDEDDEDEISVPKKKLVDPVAGAGGPGSRFKGKHSLDSDEE-DDDE-GSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNQDSQIRDSWLDNIDWVRIKER------------PPDKQQVSDSEEEGSLGQTPMSVQALLEGLLELLLPRETVAGALRRLGARGGGKG-NSKGTGRPN-----SPQRLDRLSGLADQMVAR-GNLGVYQETRERLAMRLKGLGCRTQGSHDPTPPPSLDMFAEEVTEGELETPTPTHREEADSAGDGLMDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWK3-1", "uniprot_id": "CD2B2_MOUSE", "id": "Q9CWK3-1", "name": "CD2 antigen cytoplasmic tail-binding protein 2", "aln": "MPKRKVTFQGVGDEDGEDEISVPKKKLVDPVAAAGGPGSRFKGKHSLDSDEE-DDDEEGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNQDAQIRDSWLDNIDWVRIKER------------PPDKHQVSDSEEEDSLGQTPMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGSNSKGTGRPN-----SPQRLDRLSGLADQMVAR-GNLGVYQETRERLAMRLKGLGCRAQGSHDPTPPPSLDMFAEEVAEGELETPTPTQREEAESAGDGLMDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFELYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95400-1", "uniprot_id": "CD2B2_HUMAN", "id": "O95400-1", "name": "CD2 antigen cytoplasmic tail-binding protein 2", "aln": "MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRER------------PPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKG--RKGPGQPS-----SPQRLDRLSGLADQMVAR-GNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKV5-1", "uniprot_id": "CD2B2_DROME", "id": "Q9VKV5-1", "name": "CD2 antigen cytoplasmic tail-binding protein 2 homolog", "aln": "-------------------MASKRKHQASQKVKE----ESFK-KHTLDSDEE----DSDDYEREYLNDSDIEGGEEGVAKVEDDVKVTPFNMKEELEEGHFDKDGHYHWNKETEAKDNWLDNIDWVKIGTQKNAFD-------PAKDEENSSDEEKNEPVGKAFNLSMNLMKMVEFMKPGETVKMTLQRLGKQRPVLTTLQRIKQKKAGIVDPKTQEISQLTELANEILSKTGNMDIYQDTYESIKAKIADL----PGTSKPKVADDIDMYADDFETKELER-SKTSSSDSSKPTTTTSEVTWEFKWSQD-ETDIQGPFSTEKMLKWSQENYFKNGVYVRKCG-ENTNFYTSNRIDFDLYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38852-1", "uniprot_id": "LIN1_YEAST", "id": "P38852-1", "name": "Protein LIN1", "aln": "------------MKYTQYPNSSKLKRNSDRREHDEKLSDELHNQSTIYEDEE-----LSRAEYDSDSDSSVEDSTDNENSGKEMDEKSYEKNEDHVEDHRKRKKSKIQLLDIAEFKKENLADLDYQIGNSESKVEKGVNIEPFNIDDEIKHGVFDKDGNYIKTENATENDQQDNEEWMNDVINTEEVNRLEKEQSVKTQNSRHYMVHEALN-LLKFFLVDENETVLESLGRLNKLRKIAISKKNKSLKYVIHGIELLSDLINILEKKGFSEVYEYNRLKVQDAIEEEIFDDSSRIVNHKTKLWGFKWLNK-LDEYHGLYTNYEMSYWQKS-YFKNSVIVKFHSEPDRDENWIHVSCLSFM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :: : :: .*** . : : ...:*. : . : : ::.:*: : ..: :: :.. * ::*: . .. . ::. .. . * :.** . : : . . : :.: .:: : : : . . . : ::: : .. * :** : : * ::. :* * .. ** :.* : . . : : :.: ", "identical_positions": 20, "similar_positions": 94, "identity": "5.54%" }, { "cls_id": "homologset.agr.SGD:S000001201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCH5-1", "uniprot_id": "RABEK_MOUSE", "id": "Q8VCH5-1", "name": "Rab9 effector protein with kelch motifs", "aln": "------------------------------------MRGLRQGIMKQLPILEPGDKPRKATWYTLTCPGDRPCPRVGHSCSYFPPVGDAE-----------SGKIFIVGGANPNQSFSDVHTMDLGTHQWD-----TATREGLLPRYEHASFLP--SCSPHSIWVFGGADQSGNRNCLQVMSPED-----RTWSTPEVTGSPPSPRTFHTSSAAIGNQLYVFGGGERGAQP--------------VED------VKLHVFDAN-----TLTWSQPETHGSPPSPRHGHVMVAAG------TKLFIHGGLAG---------DKFFDDLHCIDIGDMSWQKLGPTGAVPVGCAAHAAVAVG-HHVYMFGGMTAT--------------GALNMMYKYHTEKQHWTVLQFDT------SLPAGRLDHSMCVIPWPVMSTSENKDSDSVILTLQDEKGDAAEKAETQSGGPHEESPTTVLLCFVFGG--------------------MNTEGEVYDDCLVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8F4-1", "uniprot_id": "RABEK_RAT", "id": "Q4V8F4-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------------------------------------------MKQLPILEPGDKPRKAAWYTLTCPGDKPCPRVGHSCSYFPPVGEAE-----------KGKVFIVGGANPNQSFSDVHTMDLGTHRWD-----TATREGLLPRYEHASFLP--SCSPHSIWVFGGADQSGNRNCLQVMNPEA-----RTWSTPEVTGCPPSPRTFHTSSAAIGNHLYVFGGGERGAQP--------------VQD------VKLHVFDAN-----TLTWAQPETHGSPPSPRHGHAMVAAG------TKLFIHGGLAG---------DRFFDDLHCIDIGDMSWQKLGPTGTAPVGCAAHAAVAVG-HHVYVFGGMTAT--------------GALNTMYKYHTEKQHWTILQFDT------SLPPGRLDHSMCVIPWPVMSASDTEDSGSVILSLQDEKGDAAEKPETRSGGSREESPTTLLLCFVFGG--------------------MNTEGEIYDDCLVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z6M1-1", "uniprot_id": "RABEK_HUMAN", "id": "Q7Z6M1-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------------------------------------------MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAK-----------RGKVFIVGGANPNRSFSDVHTMDLGKHQWD-----LDTCKGLLPRYEHASFIP--SCTPDRIWVFGGANQSGNRNCLQVLNPET-----RTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQP--------------VQD------TKLHVFDAN-----TLTWSQPETLGNPPSPRHGHVMVAAG------TKLFIHGGLAG---------DRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMG-KHVYIFGGMTPA--------------GALDTMYQYHTEEQHWTLLKFDT------LLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLCLVFGG--------------------MNTEGEIYDDCIVTVVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GQN7-1", "uniprot_id": "RABEK_DANRE", "id": "Q6GQN7-1", "name": "Rab9 effector protein with kelch motifs", "aln": "--------------------------------------------MELIPVLEPEQKPQNRHWYVLEPTGAAPGVSVGHTCSFLPAAHHHDED------GGGKGKIVIVGGANPSGSFADSYIINLDTHQWD-----LPDWEGLQARYEHCSFTP--ESEPQSLWVFGGAEKSTNRNCVQALRFSDGGEGRRFWQSVQVTGVPPSGRTYHTNSACVGNRLFVFSGGEAGSSA--------------VTD------AQLHVFDAV-----SVTWTQPDTTGTPPAQRHGHVITAVG------SDIYIHGGMSG---------EKFHSDMFTLNTESLKWQKVKAKGDLPPGVAAHSSVTFN-KNIFIFGGMTAD--------------GATNSMFKFQCDKQRWTLLKFEG------DLPPGRLDHSMCLLPWRVK----MEDS---------------------------EHADVQHLCFVFGG--------------------MDTQGVIFNDCLVTVLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D968-1", "uniprot_id": "HCFC2_MOUSE", "id": "Q9D968-1", "name": "Host cell factor 2", "aln": "------------------------------------------MAAPS--------LLN--WRRVSSFTGPVPRARHGHRAVAIR-------------------ELMIIFGGGNEGIADELHVYNTVTNQWF-----LPAVRGDIP-PGCAAHGF--VCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPQPPPSGFPPCPRLGHS-FSLYGNKCYLFGGLANESED--------------SNNNVPRYLNDFYELELQ-HGSGVVGWSIPATKGVVPSPRESHTAIIYCKKDSASPKMYVFGGMCG---------ARLD-DLWQLDLETMSWSKPETKGTVPLPRSLHTASVIG-NKMYIFGGWVPHKGENPETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLN----TDLTYQATSSDSSAAPSVLGG------------------------------------------------------------------------------RMDPHRQGSNS-------------------------------------------------------------------------------------------------------------------------TLHNS--------------------------------------------VSDTVNSTKTEHTAVR------------------------------------------------------------------------------------------------------------------------------------------------GTSLRSKPD---------------------------------------------SRAVDSSAALHSPLAPN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSNNSSWVTDMLRKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVDEICALP--------------------------------------------------------------------------------------------------------------------------------------------ATKIS-------------------------------------------------------------------------------RVEVHAAATPFSKET-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSK-VGNADVPDYSLLKKQDLVPGTVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISKNV-DGIHLSWEPP-TSPSGNILEYSAYLAIRTAQMQ-----DNPSQLVFMRIYCGLKTSCTVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQDQEKDVG------------PWF-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61191-1", "uniprot_id": "HCFC1_MOUSE", "id": "Q61191-1", "name": "Host cell factor 1", "aln": "------------------------------------------MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIK-------------------ELIVVFGGGNEGIVDELHVYNTATNQWF-----IPAVRGDIP-PGCAAYGF--VCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHS-FSLVGNKCYLFGGLANDSED--------------PKNNIPRYLNDLYILELR-PGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSG---------CRLG-DLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIG-NKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDN---IPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASVRMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQETAASLVTSAVGQQNGNVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTSTATTAMSSMGTGQQRDTRRTTNTPTVVRITVAPGALERVQGTVKPQCQTQQTNMTTTTMTVQATGAPCSAGPLLRPSVALESGSHSPAFVQLALPSVRVGLSGPSSKDMPTGRQPETYHTYTTNTPTTTRSIMVAGELGAARVVPTSTYESLQASSPSSTMTMTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGAGQPEGGQQPASGHPCETHQTTSTGTTMSVSVGTLIPDATSSHGTLESGLEVVAVPTVTSQAGSTLLASFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVASTQGDSTNITSASAITTSVSSTLPRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTPLMGESTEVLSASQTPELQAAVDLSSTGDPSSGQEPTTSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAAVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQQLQEAQAQAQQQHHLPTEALAPADSLNDPSIESNCLNELASAVPSTVALLPSTATESLAPSNTFVAPQPVVASPAKMQAAATLTEVANGIESLGVKPDLPPPPSKAPVKKENQWFDVGVIKGTSVMVTHYFLPPD-DAVQSD-DDSGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP-DGAHLTWEPP-SVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEMKSAPKKSKADGQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V4C8-1", "uniprot_id": "HCF_DROME", "id": "Q9V4C8-1", "name": "Host cell factor", "aln": "MEGSDFVDPAFSSGERISASDLNSEHIIQAENHSFANRISMDMDVPDG-HQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINIK-------------------ELMVVFGGGNEGIVDELHVYNTVTNQWY-----VPVLKGDVP-NGCAAYGF--VVEGTRMFVFGGMIEYGKYSNELYELQATKWEWRKMYPESPDSGLSPCPRLGHS-FTMVGEKIFLFGGLANESDD--------------PKNNIPKYLNDLYILDTRGVHSHNGKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSG---------CRLG-DLWLLETDSMTWSKPKTSGEAPLPRSLHSSTMIG-NKMYVFGGWVPLVIND-SKSTTEREWKCTNTLAVLDLETMTWENVTLDTVEEN---VPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTATTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISANRSGSALG-----------LGVEATSTVLKLEKESLQLSGCQPETNVQPSVNDLLQSMSQPSSPASRADKDPLSSGGGTTFNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTAVSIATSTSDPLSVRVPSTMSANVVLSSSSSTLRIVPS--VTASHSLRIASSQASGNNCRSSSAINILKTALPNVAVQSQPTSSTTTSIGGKQYFIQKPLTLAPNVQLQFVKTSGGMTVQTLPKVNFTASKG--------------------------------------TPPHGISIANPHLASGITQIQGSTVPGSQIQKPIVSGNVLKLVSPHTMAGGKLIMKNSNILQMGKVTPNVMGGKPAFVITNKQGTPLGNQQIIIVT-------TGGNVRSVPTS-----------------------------TVMTSAGGSASGTNIVSIVNSTSTTPSPLQALSGQKTLIS-----------------------------------------------------NQSGVKMLRNISSVQASSSMAFGQKQSGTPIHQKTALYIGGKAVTVMSTNTSMAASGNKVMVLPG----------------------------------------------TSSNNSPATTTALSARKSFVFNAGGSPRTVTLATKSINAKSIPQSQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------PVTETNNHSVATIKDTDPMDDIIEQLDGAGDLLKLSESEGQHGSE----------------------------------------------------------------------------------------------ENENNGENATSSSASALFTGGDTAGPSRAQNPIVMEHPVDIIEDVSGVSSTTDVNETAIVSGDTIESLKMSEKENDDVKSMGEKSILSDDCHQPTTSETEAATILTTIKSAEALVLETAEIRKDHTGCTIGSLKENQDENKKFKQRQESSPSQNIHQFQNVDGSQLEALASAALLQAATSDTTALALKELIERPESETNTRSSNIAEIQ---------------------------------------------------------------------------------------------------------------------------------------------------------------QNNVQSTLAVVVPNTSQNENQKWHTVGVFKDLSHTVTSYIDSNCISDSFFDGIDVDNLPDFSKFPRTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQKTKEIIEYSVYLAVKPTAKD---KALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPAIIFRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLKRGPEKSTIGSSNIANTFCSPHKRGRNGLHD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8VEM9-1", "uniprot_id": "KLDC3_MOUSE", "id": "Q8VEM9-1", "name": "Kelch domain-containing protein 3", "aln": "-----------------------------------------------------------MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGG---------------YCSGEDYETLRQIDVHIFNAVSLRWTKLPPVRPAVRGQAPVVPYMRYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVN----THKWSTPRVSGTVPGARDGHS-ACVLGKIMYIFGGYEQLADC--------------FSN-------DIHKLDTS-----TMTWTLVCTKGNPARWRDFHSATMLG------NHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPHTPVLPEGRRSHSAFGYN-GELYIFGGYNARLN------------RHFHDLWKFNPGSFTWKKIEPKG------KGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYSLDQSCLPHDIR------------WELNAMTTNSNISRPIVSSHG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G5Y1-1", "uniprot_id": "KLDC2_MOUSE", "id": "Q4G5Y1-1", "name": "Kelch domain-containing protein 2", "aln": "-------------------------------------------MADGNEDARAEDLPGPAFENYEAMELACPAERSGHVAVSDGRHMFVWG---------GYKSNQVRGLYDFYLPREELWIYNMETGRWK-----KINTEGDVPPSMSGSCAV---CVDRVLYLFGGHHSRGN-TNKFYMLDSRSADRGLQWERIDCQGIPPSSKDKLG-VWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTE-----TFAWSQPITTGKAPSPRAAHACATVG------NKGFVFGGRYR---------DARMNDLHYLNLDTWEWNELIPQGVCPVGRSWHSLTPVSSDHLFLFGGFTTEK-------------QPLSDAWTYCISKNEWIQFNHPY-------VEKPRLWHTACASDEGEVIVFGGCANNLLVHHRAAHSNEVLIFSVQPKSLVRLSLEAVICFKEMLAN-------------------SWSCLPKHLLHSVNQRFGSNNTSGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38853-1", "uniprot_id": "KEL1_YEAST", "id": "P38853-1", "name": "Kelch repeat-containing protein 1", "aln": "--------------------MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTKQETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAVPPQQRNVSGPSTTLHKQLSKQREYTVWN-RIKLQNSPFPRYRHVASAY--VTDKNQIYVIGGLHDQSVYGDTWILTAFDN-ATRFSTTTIDISEATPPPRVGHA-AVLCGNAFVVFGGDTHKVNK------------------EGLMDDDIYLLNIN-----SYKWTVPAPVGPRPLGRYGHKISIIAT-TQMKTKLYVFGGQFDDTYFN----DLAVYDLSSFRRPDSHWEFLKPRTFTPPPITNFTMISYD-SKLWVFGGDTLQG--------------LVNDVFMYDPAINDWFIIDTTG------EKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFTAGIPQGRSGHSLTLLKNDKILIMGG----------DKFDYARVEEYDLHTSDIDMQRGTIVYTLDLARIKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKDFSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEIKTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIGVAQMASSPSKDQFKIKHYNESSELSQN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NTEIDKLSEPVDITIKKSD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAGHDSANHVIDASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKALEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNELEELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNESKQHN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKENEIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENFENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLLNLENNTKQVNEDADSDLL----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .: .. . : : ** . * : : .*.* . ..: :: * . * . * * . :.** : : * * .: . .:::*** * . : . ", "identical_positions": 17, "similar_positions": 37, "identity": "0.79%" }, { "cls_id": "homologset.agr.SGD:S000001204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TTZ3-1", "uniprot_id": "A0AB32TTZ3_DANRE", "id": "A0AB32TTZ3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFAAPETAAAAEGGAT-----ASTPTPAADGTAPAESAG----------------------------------------------------------------------ASEAKPAA------------------------------------------------------------------AAAAGGGGGDLM-------------------------------------------------------------SAFDGLGDVLMPAMAP--QAAGASPMASS-----------------------------------PVKPMGGDLDSAMANMAGNLGMG---NQKPG---------EAAGGANWQ-------------------------------------AQTPTIGVCPVMGSPSP-FGMP-----AGGAAPMMPGSPMMAAQQPVRPQFP----AGAPGQPMSPG---MAQSPRKPPPPKDPLADLNIKDFM----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T6A8-1", "uniprot_id": "A0A8N7T6A8_DANRE", "id": "A0A8N7T6A8-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSLTGSEVARAVCKATTHEVMAPKKKHLEYLIQATQESNVNIPQMADTLFERAGNASWIVVFKALVATHHLMVHGN-ERFIQYLASRNTLFNLSNFLDK-----------TGSHGYDMSTFIRRYSRYLNEKAFAYRQMAFDFG-------RVKKG--ADGVMRTMTPDKLLKGMPTLQSQIDALLEFDVHPKDLVNGVINAAFLLLFKDLIKLYACYNDGIINLLEKFFQMKKGQCKDALEIYKRFLTRMTRVSEFLKIAEQVGIDKNDIPELTQ-------APESLLESLETHLNTLEGKKVSP----------TKKGSPTNNGTPAGTPAKSAEPSAAVTEPAASEPTKAAPAKTTINSGFNDLVDFDLLAPTAGVSAAP------TASWGDLLGGDSLAAPASASSEAPLSEAESASAAAATEPAADAISAPAAASLPVPTSTATTSDMDLFGDAFAPSPGDGPSEGF---------APAAAADACAGSDPWATSEGSASIAPELDLFAMKPVESVSVAAAASPTSAEPVISPTEAPETLSPATNTTT-----TTSTTTTVTASATAEPAAPPTLDLFSDMFDSMPEQSSSTEPKASTPSVDLFGADLPAVSRGPSPLPETNVTGDLLSDSFVAPAVAPVVPAPAAPAAPVSPPKAEPGPVL---------------------------------------DLLDTFGDTTAESQSAAPGAPSGDLLGGLISPVAPTVTPTPAVVPSSAPADLLESGFDAFGSLPVSSTPVVVDSTNSTTAPSGGFDASVFDGLGDLLMPAITP--QSTGGTPMAAASPQLAPGLMPTAGPTMVPAMAPAMAPTMVPAAAAQPVKPIGGDLDSSLANLVGNLGVV---SQKKDNQW--NE-KKLTGGANWTPQVALSSWGT-PGAQMPG------------SAPGAPGAAAPPGAMAPPMGAQPS-FGMPP----AAAGAPIMP-QPVMMGQPMMRPQFTGPSATGTPGAPLSPGP--AAQSPKKPPS-KDPLADLNIKDFL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O60641-1", "uniprot_id": "AP180_HUMAN", "id": "O60641-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHGN-ERFIQYLASRNTLFNLSNFLDK-----------SGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFA-------RVKKG--ADGVMRTMAPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQ-------APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASAS--TTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT--APPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFG-------------------------------------------SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFG----------------TTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP-------------------------------AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGE-KKLTGGANWQPKVAPATWSAGVPPSAPL------------QGAVPPTSSVPPVAGAPSVGQPGAGFGMPP----AGTGMPMMPQQPVMFAQPMMRPPFG---AAAVPGTQLSPSPTPASQSPKKPPA-KDPLADLNIKDFL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61548-1", "uniprot_id": "AP180_MOUSE", "id": "Q61548-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHGN-ERFIQYLASRNTLFNLSNFLDK-----------SGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFA-------RVKKG--ADGVMRTMVPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQ-------APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDIFATASAAAPVSSAKPSSDLLDLQPDFS--GAAAGAAAPVVPPSGGATAWGDLLGEDSLAALSSVPCEAPISDPFAPEPSPPTTTTEP--ASASAS--TTTAVTAVTTEVDLFGDAFAASPGEAPAASEGATAPATPAPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSAPVVTPTASTAPPVPATAPSPAPTAVAATAATTTAAAAATTTATTSAAAATTAAAPPALDIFGDLFDSAPEVAAAPKPDAAPSIDLFGTDAFSSPPRGASPVPESSLTADLLSVDAFAAPSPASTASPAKAESSGVIDLFGDAFG-------------------------------------------SGASETQPAPQAVSSSSASADLLAGFGGSFMAPSTTPVTPAQNNLLQPSFEAAFG----------------TTPSTSSSSSFDPSVFDGLGDLLMPTMAPSGQPAPVSMVPPSP-------------------------------AMAASKGLGSDLDSSLASLVGNLGISGTTSKKGDLQWNAGE-KKLTGGANWQPKVTPATWSAGVPP----------------QGTVPPTSSVPPGAGAPSVGQPGAGFGMPP----SGTGMTMMSQQPVMFAQPMMRPPFG---AAAVPGTQLSPSPTPATQSPKKPPA-KDPLADLNIKDFL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7M6Y3-1", "uniprot_id": "PICAL_MOUSE", "id": "Q7M6Y3-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFT-------KVKRG--ADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ-------APSSLLDALEQHLASLEGK----------------------KIKDSTAASRATTLSNAVSSLASTGLSL-----------------------------------------------------------------------------------------------------------------------------------------------TKVDEREKQAALEEEQARLKALK---EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS---SNSTSKLPNDLLDLQQPTFHPSVHAMSAAPQGASTWGDPFSATLDAVEDAIPSLNPFLTKSSGD-VHLPIAS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFSPSPVAQPHSSAGLNVDFESVFGNKSTN-------------------------------------------VAVDSGGFDELGGLLKPTVASQNQSLPVAKLPPN-------------------------------------KLVSDDLDSSLANLVGNLGIG-NGTTKNDVSWSQPGEKKLTGGSNWQPKVAP-TTAWSAATMN---------------GMHFPQYAPPVMAYPATTPTGMIGYGIPP----QMGSVPVMTQPTLIYSQPVMRPPNP---FGPVSGAQIQFM-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55012-1", "uniprot_id": "PICAL_RAT", "id": "O55012-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFT-------KVKRG--ADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ-------APSSLLDALEQHLASLEGK----------------------KIKDSTAASRATTLSNAVSSLASTGLSL-----------------------------------------------------------------------------------------------------------------------------------------------TKVDEREKQAALEEEQARLKALK---EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS---SNSTSKLPNDLLDLQQPTFHPSVHAMSAAPQVASTWG-------DAVDDAIPSLNPFLTKSSGD-VHLPISS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFSPSPVTQPHPSAGLNVDFESVFGNKSTN-------------------------------------------VAVDSG-----GGLLKPTVASQNQSLPVAKLPPN-------------------------------------KLVSDDLDSSLANLVGNLGIG-NGTTKNDVSCSQPGEKKLTGGSNWQPKVAP-TTAWSAATM-----------------------APPVMAYPATTPTGMIGYGIPP----QMGSVPVMTQPTLIYSQPVMRPPNP---FGPVPGAQIQFM-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13492-1", "uniprot_id": "PICAL_HUMAN", "id": "Q13492-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFT-------KVKRG--ADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ-------APSSLLDALEQHLASLEGK----------------------KIKDSTAASRATTLSNAVSSLASTGLSL-----------------------------------------------------------------------------------------------------------------------------------------------TKVDEREKQAALEEEQARLKALK---EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS---SNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGD-VHLSISS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFTPSPVAQPHPSAGLNVDFESVFGNKSTN-------------------------------------------VIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPS-------------------------------------KLVSDDLDSSLANLVGNLGIG-NGTTKNDVNWSQPGEKKLTGGSNWQPKVAP-TTAWNAATM-----------------------APPVMAYPATTPTGMIGYGIPP----QMGSVPVMTQPTLIYSQPVMRPPNP---FGPVSGAQIQFM-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GJ72-1", "uniprot_id": "A0AC58GJ72_DANRE", "id": "A0AC58GJ72-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSITDRITAAQHIVTGSAVSKTVCKATTHEVMGPKKKHLDYLIQCTNEMNVNIPQLADTLFERTTNTSWVVVFKSLITTHHLMVYGN-ERFVQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFT-------KVKRG--ADGVMRTMNTEKLLKTIPIIQNQMDALLDFNVNANELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKAQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ-------APSSLLDALEQHLASLEGK----------------------KVKDSTAASRASTLSNAVSSLANTGISF-----------------------------------------------------------------------------------------------------------------------------------------------TKADEREKQAALEEEQARLKALK---EQRLKELSKKPSTTSTTAASPVSTETGSISTVPAIDLFSATSTF--ANSTPKVPNDLLDLQ-PAFQPSLP-LSSGLPLANTWGDPFTST-EAADDSIPNLNPFLTKPVVDPVHLPVVSSDAVSFSSRTPSHEMFGDSF-------------------------------CSPTAYPNTPLFHSEPSTVAGLFGGFSAPPAAQPPSSTGLNVDFDSVFGNKSVA-------------------------------------------NSTDSAD-DILGGILKPTVTSPNQGLTPSAQLSG-------------------------------------KLVSDDLDSSLANLVGNLGIG-NGTAKNDIHWSQPGEKKLTGGMNWQPKTAP-TTTWNPATMN---------------GMLFPQYAPSVMAFPATTPTGMMGYAMPP----QMGSMAMMTQPTMMYTQPVMRPANP---FGPVSGAQLSTASSPSSSSPLRAPG-QDPFAQLSMKDFL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z9M1-1", "uniprot_id": "A0A8M6Z9M1_DANRE", "id": "A0A8M6Z9M1-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSITDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIHCTNEMNVNIPQLADSLFERTTNTSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFT-------KVKRG--VDGVMRTMNTEKLLKTIPIIQNQMDALLDFNVNANELTNGVINAAFMLLFKDSIRLFAAYNEGIINLLEKYFDMKKVQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQFTV---CAPSSLLDALEQHLASLEGK----------------------KVKDSTAASRASTLSNAVSSLANTGMSF-----------------------------------------------------------------------------------------------------------------------------------------------TKVDEREKQAALEEEQARLKALKQ--EQRLKELSKRP-SFATTDTSPVSTTAACISTAPAIDLFSTPSC---SNGALKMESDLFDLQ-TNFQSSMQ---PGPSVATAWGDPFSSS-EAVDDSIPNLNPFLSKLVVDGAHLPVMSSDGVSFSSRTSGHEIFSDQYNPFIDSSSSVSTNYKRTVRIEHLISDSFGQPSMVQHLPNPSPFQSEPSTVAGLFRGYGAPQMPPPQNSGELRVDFESVFGTKAASS------------------------------------------NSLDTD-----AGILKPTVAGSSQ---SSNQLPE-------------------------------------KLVSDDLDSSLANLVGNLGIG-NGTTKNDIHWSQPGEKKLTGGMNWQPKTAP-STTWNPVSMP-----------------------PSIMAFPATTPTGMMGYGMPP----QLPSMSMMTQPTMMYTQPVMRPSNP---FGSVSSAQPSAASSPSSQSPLRAPG-QDPFAQLSLKDFL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TVT4-1", "uniprot_id": "A0AB32TVT4_DANRE", "id": "A0AB32TVT4-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSITDRIAAAQHSMTGSAISKAVCKATTHEVSGPKKKHLDYLIHCTNEMNVNVPQLADTLFERTTNSSWVVVFKALITTHHLMMYGN-ERFIQYLASRNTLFNLNNFLDK-----------GALQGYDMSTFIRRYSRYLNEKALSYRLVAVDFT-------KMKRG--IDGVMRTMNTEKLIKTLPIIQNQLDALLDFQANPNELTNGVINAAFMLLFKDSIRLFAAYNEGVINLLEKYFDMKKNQCKDALDIYKKFLYRMTKLSEFLKVAEQVGIDQGDIPDLTQTTRGSYLAPSSLLEALEQHLASLEGK----------------------KTKELSADNRANTLSNAVSSLSNTGMSFSFSS-------------------------------------------------------------------------------------------------------------------------------------------SRMDEKEKQQALEEEQARLQALK---NQRLKEIGMQTPTASPSTQSLGSANN----HNADVDLFTNTTSPPSINSMPNLTSDLFDLQ-PAFVPAVQS-TPISTASSAWG--------------------------------------------------------------------------------------------------------------GVESSTLHSMTSMPTMNVDFDAVFGTKASNT------------------------------------------DVKPSAGYDASGDLLKPTVTVHSQTPVMHHHTGS-------------------------------------KLLANDLDSSLANLVGNLQFGGTPGKKSDMQWTQPGEKKLTGGTNWQSKTMSSTTAWSPAPLPPAAMPPAAMPVPHMTGMFYTSYAPAPMAFPMTTPQ-VPVYGMVPPQLGQMGGVPVMTQQPMLYNQPVLRPTNP---FTPIPGAQMQFM-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI75-1", "uniprot_id": "PICAL_DROME", "id": "Q9VI75-1", "name": "Phosphatidylinositol-binding clathrin assembly protein LAP", "aln": "MTMAGQTINDRLLAARHSLAGQGLAKSVCKATTEECIGPKKKHLDYLVHCTNEPNVSIPHLANLLIERSQNANWVVVYKSLITTHHLMAYGN-ERFMQYLASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSLSYRAMAFDFC-------KVKRGK-EEGSLRSMNAEKLLKTLPVLQAQLDALLEFDCQSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAENVGIDKGDIPDLTK-------APSSLLDALEQHLATLEGR----------------------KVSAANTPTQSSSSAFGTAAASSKFDTT-----------------------------------------------------------------------------------------------------------------------------------------------NGIDEQLKAQVLAEEEAAMNQYK------------------SKVSSPTSSGAAGASAALTNPFLSSPPA----------------------------------------------------------------------------------------------------------------------------------------------------------AQAGQP---------IVDLFGAASAQ-----------------------------------------------------------PAAAAAATKASDDLLQLG-------------------------------------NPFADMFDASGG---GAAAVG---ATGN----AGDGTAKYDGGAGSSP-----------------------------------------FDWGATDDDGGAAQ-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38856-1", "uniprot_id": "AP18A_YEAST", "id": "P38856-1", "name": "Clathrin coat assembly protein AP180A", "aln": "--------------------MTTYFKLVKGATKIKSAPPKQKYLDPILLGTSN-EEDFYEIVKGLDSRINDTAWTIVYKSLLVVHLMIREGSKDVALRYYSRNLEFFDIENIRGS-----------NGSASGDMRALDR-YDNYLKVRCREFGKIKKDYVRDGYRTLKLNSGNYGSSRNKQHSINIALDHVESLEVQIQALIKNKYTQYDLSNELIIFGFKLLIQDLLALYNALNEGIITLLESFFELSHHNAERTLDLYKTFVDLTEHVVRYLKSGKTAGLKIPVIKHITT----------KLVRSLEEHLIEDDKT---------------------HNTFVPVDSSQGSAGAVVAKSTAQER-----------------------------------------------------------------------------------------------------------------------------------------------LEQIREQKRILEAQLKNEQVAISPALT--TVTAAQSYNPFGTDSSMHTNIPMAVANQTQQIANNPFVSQTQPQVMNTPTAHTEPANLNVPEYAAVQHTVNFNPVQDAGVSAQQTG-----------------------------------------------------------------------------------------------------------YYSINNHLTPTFTGAGFGGYSVSQDTTAASN------------------------------------------QQVSHSQTGSNNPFALHNAATIATGNPAHENVLNN------------------------------------PFSRPNFDEQNTNMPLQQQIISNPFQNQTYNQQQFQQQKMPLSSINSVMTTPTSMQGSMNIPQR----------------------FDKMEFQAHYTQNHLQQQQQQQ---QQQQQQQQQQPQQGYYVPATAGANPVTNITGTVQPQNFPFYPQQQPQPEQSQTQQPVLGNQYANNLNLIDM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :* . : . ", "identical_positions": 1, "similar_positions": 7, "identity": "0.09%" }, { "cls_id": "homologset.agr.SGD:S000001205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38718-1", "uniprot_id": "MPC2_RAT", "id": "P38718-1", "name": "Mitochondrial pyruvate carrier 2", "aln": "------------------MAAAGAR-------------GLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLAD-MARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWKYNQELKS---------KGIQ-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D023-1", "uniprot_id": "MPC2_MOUSE", "id": "Q9D023-1", "name": "Mitochondrial pyruvate carrier 2", "aln": "------------------MAAAGAR-------------GLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLAD-MARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWRYNQELKS---------KGIQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95563-1", "uniprot_id": "MPC2_HUMAN", "id": "O95563-1", "name": "Mitochondrial pyruvate carrier 2", "aln": "------------------MSAAGAR-------------GLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLAD-MARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKA---------KAHK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2B8-1", "uniprot_id": "A0A8M1N2B8_DANRE", "id": "A0A8M1N2B8-1", "name": "Mitochondrial pyruvate carrier", "aln": "------------------MNMNSGRLYSRLRLCRFYSGGVRATYHRTLDRIELMLPPKLRPVYNHPAGPKTVFFWAPVFKWGLVAAGFSD-MTRPPEKLSVSQSCVITATGLIWSRYCLVIIPKNWALFAVNFFLGMCGSIQLFRIWRYNQELKQ---------KEAEVQQT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHB2-1", "uniprot_id": "Q9VHB2_DROME", "id": "Q9VHB2-1", "name": "Mitochondrial pyruvate carrier", "aln": "MSAT----PPTTPAP--TAAASAGKG------------LHSRAYNGLIKACDKYVPPKMRPLWMHPAGPKTIFFWAPIVKWSLVIAGLSD-LTRPADKISPNGCLALGATNLIWTRYSLVIIPKNYSLFAVNLFVSLTQLFQLGRYYNYQWEQSR---------LEKNGEQCPAIEASL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHB1-1", "uniprot_id": "Q9VHB1_DROME", "id": "Q9VHB1-1", "name": "Mitochondrial pyruvate carrier", "aln": "MSSTAVQPPPPVPPPPPSAVPSAGKG------------IHSKLYNGMIGAADKFVPAKLRPLWMHPAGPKTIFFWAPVFKWGLVAAGLSD-LARPADTISVSGCAALAATGIIWSRYSLVIIPKNYSLFAVNLFVGITQVVQLARAYHYHQSQEK---------LKQE-QQQPAVQN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INZ7-1", "uniprot_id": "Q8INZ7_DROME", "id": "Q8INZ7-1", "name": "Mitochondrial pyruvate carrier", "aln": "--------------------MSKGTG------------PLSKLYNITISTIDKFVPGAVQPLWQSPAGPRTVFFWAPAFKWSLVLAGLSDTLSRPPANISLNQCGSLAVTGLIWSRYSVVITPKNYNLLAVNIAVFLIQGYLMVKHLRWRSENSR---------NAVFNHSHYPIKSGDDW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38857-1", "uniprot_id": "MPC2_YEAST", "id": "P38857-1", "name": "Mitochondrial pyruvate carrier 2", "aln": "--------------------MSTSS-----------------------------VRFAFRRFWQSETGPKTVHFWAPTLKWGLVFAGFSD-MKRPVEKISGAQNLSLLSTALIWTRWSFVIKPRNILLASVNSFLCLTAGYQLGRIANYRIRNGDSISQLCSYILSGADESKKEITTGR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: .: :**:*:.**** .**.** **::* : ** .:* : * :**:*:..** *:* * :** : : : .:. ", "identical_positions": 28, "similar_positions": 31, "identity": "15.47%" }, { "cls_id": "homologset.agr.SGD:S000001206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85971-1", "uniprot_id": "6PGL_RAT", "id": "P85971-1", "name": "6-phosphogluconolactonase", "aln": "MAAPAPGLISVFSSPQE-LGASLAQLVAQRAASCLEGNRGRFALGLSGGSLVSMLARDLPAATAPAGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLP-IPDSQVLTIDPALPVEDAAEDYARKLRQAFQGDTVPVFDLLILGVGPDGHTCSLFPGHP---LLQEREKIVAPIGDSPKPPPQRVTLTLPVLNAAQSVIFVATGEGKAAVLKRILEDQE-SALPAAMVQPRTGALC-WFLDEAAARLLSVPFEKHSTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ60-1", "uniprot_id": "6PGL_MOUSE", "id": "Q9CQ60-1", "name": "6-phosphogluconolactonase", "aln": "MAAPAPSLISVFSSPQE-LGASLAQLVAQRAASCLEGDRGRFALGLSGGSLVSMLARDLPAAAAPAGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLP-IPDSQVLTINPALPVEDAAEDYARKLRQALQGDAVPVFDLLILGVGPDGHTCSLFPDHP---LLQEREKIVAPISDSPKPPPQRVTLTLPVLNAAQSIIFVATGEGKAAVLKRILEDKE-GTLPAALVQPRTGALC-WFLDEAAARLLSVPFEKHSTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95336-1", "uniprot_id": "6PGL_HUMAN", "id": "O95336-1", "name": "6-phosphogluconolactonase", "aln": "MAAPAPGLISVFSSSQE-LGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPAAVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLP-IPESQVITINPELPVEEAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHP---LLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLC-WFLDEAAARLLTVPFEKHSTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ64-1", "uniprot_id": "6PGL_DROME", "id": "Q9VZ64-1", "name": "Probable 6-phosphogluconolactonase", "aln": "MSEKKGALKVIPSASEEQLVQALGDLLQRCSQEALA-KHDKFSVGLSGGSLVQLLTKALKSCNLKT-----AKWVFFFCDERYVRLDDSDSTYGAYRAEWLTQLPCIQESQFVRADTSQPLDACAADYEAKVKSQVDR-----FDLLLLGMGPDGHTCSLFPEQPA--TLQETKRLVIPIRNSPKPPPERITFTLPLINKARNVAFVVTGAAKASVVKSVFVDLD-KKFPAAWVNPTKGQLT-LIVDAGAGKEIETLK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38858-1", "uniprot_id": "SOL3_YEAST", "id": "P38858-1", "name": "6-phosphogluconolactonase 3", "aln": "-----MVTVGVFSERAS-LTHQLGEFIVKKQDEALQ-KKSDFKVSVSGGSLIDALYESLVADESLSSRVQWSKWQIYFSDERIVPLTDADSNYGAFKRAVLDKLPSTSQPNVYPMDESLIGSDAESN--NKIAAEYERIVPQVLDLVLLGCGPDGHTCSLFPGETHRYLLNETTKRVAWCHDSPKPPSDRITFTLPVLKDAKALCFVAEGSSKQNIMHEIFDLKN-DQLPTALVNKLFGEKTSWFVNEEAFGKVQTKTF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * *.::: : .* : * :.:*****:. * . * : : ::* : *.*** * : .::*.** :: * :** :.:. : . . : *: : :**::** *********** .. *:* : * :*****.:*:*:***::: *: : **. * .* ::: :: : :*:* *: * ::: * : . ", "identical_positions": 63, "similar_positions": 72, "identity": "23.86%" }, { "cls_id": "homologset.agr.SGD:S000001207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG52-1", "uniprot_id": "DNA2_RAT", "id": "D3ZG52-1", "name": "DNA replication ATP-dependent helicase/nuclease DNA2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLDDLDLLLLEEDSGAEAVPRMEILQKKADAFFAETVLSRGVDNRYLVLAVETKLNERGAEEKHLLITVSQEGEQ-----------------EVLCILRNGWSSVPVEPGDIIHIEG--DCTSEPWIVDDDFG---------YFILSPDMLISGTSVASSIRCLRRAVLSETFRVS-DTATRQMLIGTILHEVFQKAISESFAPEKLQELALQTLREVRHLKEMYRLNLSQDEVRCEVEEYLPSFSKWADEFMHKGTKAEFPQMHLSLPSDSSDRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKTKYKIMPLELKTGKESNSIEHRGQVILYTLLSQERREDPEAGWLLYLKTG-QMYPVPANHLDKRELLKLRNQLAFSLLHRVSRAAAGEE-ARLLALPQIIEEEKTCKYCSQMGNCALYSRAV-EQVHDTSIPEGMRSKIQEGTQHLTRAHLKYFSLWCLMLTLESQSKDTKKSHQSIWLTPASKLEESGNCIGSLVRTEPVK-RVCDGHYLHNFQRK----NGPMPATNLMAGDRIILSGEERKLFALSKGYVKRIDTAAVTCLLDRNLS----------------------------TLPETTLFRLDREEKHGDINTP------------------LGNLSKLMENTDSSKRLRELIIDFKEPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQSHKVHPDIQKFTEEEMCRLRSIASLAHLEELYNSHPVVATTCMGISHPMFSR--KTFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHKQLPPLVLNREARALGMSESLFKRLERNE-SAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVR--LEFYAD----------------------YSDNPWLAGVFEPDNPVCFLNTDKVP-APEQIENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGIIAPYRQQLRTITDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSN------EDGTLGELLKDWRRLNVAITRAKHKLILLGSVSSLKRFPPLEKLFDHLNA----------EQLISNLPSREHESLYHILGDCQRD---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQJ5-1", "uniprot_id": "DNA2_MOUSE", "id": "Q6ZQJ5-1", "name": "DNA replication ATP-dependent helicase/nuclease DNA2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLDELDLLLLEEDGGAEAVPRVELLRKKADALFPETVLSRGVDNRYLVLAVETSQNERGAEEKRLHVTASQDREH-----------------EVLCILRNGWSSVPVEPGDIVHLEG--DCTSEPWIIDDDFG---------YFILYPDMMISGTSVASSIRCLRRAVLSETFRGS-DPATRQMLIGTILHEVFQKAISESFAPERLQELALQTLREVRHLKEMYRLNLSQDEILCEVEEYLPSFSKWAEDFMRKGPSSEFPQMQLSLPSDGSNRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKMKYKVMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGWLLYLKTG-QMYPVPANHLDKRELLKLRNWLAASLLHRVSRAAPGEE-ARLSALPQIIEEEKTCKYCSQIGNCALYSRAVEEQGDDASIPEAMLSKIQEETRHLQLAHLKYFSLWCLMLTLESQSKDNRKTHQSIWLTPASELEESGNCVGNLVRTEPVS-RVCDGQYLHNFQRK----NGPMPATNLMAGDRIILSGEERKLFALSKGYVKKMNKAAVTCLLDRNLS----------------------------TLPATTVFRLDREERHGDISTP------------------LGNLSKLMESTDPSKRLRELIIDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATTCMGINHPIFSR--KTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFKRLERNE-SAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQLYAD----------------------YSDSPWLAGVLEPDNPVCFLNTDKVP-APEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSN------EDGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNA----------EQLILDLPSREHESLSHILGDCQRD---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51530-1", "uniprot_id": "DNA2_HUMAN", "id": "P51530-1", "name": "DNA replication ATP-dependent helicase/nuclease DNA2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQLNELELLMEKSFWEEAELP-AELFQKKVVASFPRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLEN-----------------KELCILRNDWCSVPVEPGDIIHLEG--DCTSDTWIIDKDFG---------YLILYPDMLISGTSIASSIRCMRRAVLSETFRSS-DPATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTG-QMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQK-TQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVK-IVCDGQYLHNFQCK----HGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLS----------------------------VLPESTLFRLDQEEKNCDIDTP------------------LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSR--KIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNK-SAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYAD----------------------YSDNPWLMGVFEPNNPVCFLNTDKVP-APEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSN------KDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNS----------EKLIIDLPSREHESLCHILGDFQRE---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38859-1", "uniprot_id": "DNA2_YEAST", "id": "P38859-1", "name": "DNA replication ATP-dependent helicase/nuclease DNA2", "aln": "MPGTPQKNKRSASISVSPAKKTEEKEIIQNDSKAILSKQTKRKKKYAFAPINNLNGKNTKVSNASVLKSIAVSQVRNTSRTKDINKAVSKSVKQLPNSQVKPKREMSNLSRHHDFTQDEDGPMEEVIWKYSPLQRDMSDKTTSAAEYSDDYEDVQNPSSTPIVPNRLKTVLSFTNIQVPNADVNQLIQENGNEQVRPKPAEISTRESLRNIDDILDDIEGDLTIKPTITKFSDLPSSPIKAPNVEKKAEVNAEEVDKMDSTGDSNDGDDSLIDILTQKYVEKRKSESQITIQGNTNQKSGAQESCGKNDNTKSRGEIEDHENVDNQAKTGNAFYENEEDSNCQRIKKNEKIEYNSSDEFSDDSLIELLNETQTQVEPNTIEQDLDKVEKMVSDDLRIATDSTLSAYALRAKSGAPRDGVVRLVIVSLRSVELPKIGTQKILECIDGKGEQSSVVVRHPWVYLEFEVGDVIHIIEG-KNIENKRLLSDDKNPKTQLANDNLLVLNPDVLFSATSVGSSVGCLRRSILQMQFQDPRGEPSLVMTLGNIVHELLQDSIKYKLSHNKISMEIIIQKLDSLLETYSFSIIICNEEIQYVKELVMKEHAENILYFVNKFVSKSNYGCYTSISGTRRTQP----ISISNVIDIEENIWSPIYGLKGFLDATVEANVE---NNKKHIVPLEVKTGK-SRSVSYEVQGLIYTLLLNDRYEIPIEFFLLYFTRDKNMTKFPSVLHSIKHILMSRNRMSMNFKHQLQEVFGQAQ-SRFELPPLLRDS--SCDSCFIKESCMVLNKLLEDGTPEESGLVEGEFEILTNHLSQNLANYKEFFTKYNDLITKEESSITCVNKELFLLDGSTRESRSGRCLSGLVVSEVVEHEKTEGAYIYCFSRRRNDNNSQSMLSSQIAANDFVIISDEEGHFCLCQGRVQFINPAKIGISVKRKLLNNRLLDKEKGVTTIQSVVESELEQSSLIATQNLVTYRIDKNDIQQSLSLARFNLLSLFLPAVSPGVDIVDERSKLCRKTKRSDGGNEILRSLLVDNRAPKFRDANDDPVIPYKLSKDTTLNLNQKEAIDKVMRAEDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLGMKHKVHPDTQKYVPNYAS----VKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESAN----------------------SKQ--WLEDILEPTRKVVFLNYDNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFNKNVYDGLEILTADQFQGRDKKCIIISMVRRN------SQLNGGALLKELRRVNVAMTRAKSKLIIIGSKSTIGSVPEIKSFVNLLEERNWVYTMCKDALYKYKFPDRSNAIDEARKGCGKRTGAKPITSKSKFVSDKPIIKEILQEYES", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IRL9-1", "uniprot_id": "Q8IRL9_DROME", "id": "Q8IRL9-1", "name": "DNA replication ATP-dependent helicase/nuclease", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATKRVLTPNILENDNTDVTSSNPQKKFKEQLDFSSDEVENIDWGDNDDFDLALIAAMDSISNHRLELTKWQRCEVVRLEQLPNRKGLKVHVKRISGGDP----------------ETADCQLLPPWNCMPMQVGDTVSLLGKWDPSAGCYVVDKEQG---------YCVSHPDFLISGTTVTGSLFCKRKSVLQERFRGL-DSGNSVMVIGTLVHELLQKVLRQKLFDKKHIQSALQEMLAS---SSLAHLLYASNLIQVEMEDHLMKFIDPIVSFVAQYVKGEPPSVLLPEVYRG---------QIHEICDIEENLWVPQLGLKGKVDVSVKVKNQ---RQREEIIPLELKTGRASFSMEHKGQLLLYQLMHSAQGRDTQSGLLLYLKEG-LLREVASGRNEQRDLLMLRNDLAYWLTREVAIPASKEDPLEQLPLPEPVYHHSACGNCAYNTICSSFAQKDSSLQLSDS--HPLKKLMPQLLEHLSEADHAYVQHWCGLLALEEQHNRQSSHVRSFWTKDPAEREKEGIAIRHLKLVKGQEVILEEGRYRQTLELGEEADPSRDLSLSGFDLGEYVVISS-TSRLAVAAGFIVSIEARRLDLRLERDLS----------------------------QRYSEETFIIDKHDSQSFATFN------------------FTNLGMLLSEGERFQELRDIIVAKKPP----EQHKVLPKIILTKGAPILLNLNKVQQNAALRALTTSSHLLIKGLPGTGKTQTLVALVRLLHLLGKSVLITAQTHSAVDNLIMRLLPFGLPMMRLGSGSRIHKQLEEISEERLT--KDCKTVEELEKALGQPSIVGVTCLGCGHPLFQR--RQFDYCIVDEATQVLQPTVLRPLIHCSKFVLVGDPEQLPPIVRSKEARQRGADETLFQRLDSEK--ATAVLSLQYRMNKTITRLANELTYGGDLKCASDEVSGARFEVELLNEAPRWVQRALTTHLEQAVTLINTGDCLERCQEFVYASQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVSKYTNYCEAGIVMHLLRYLLKSGYEASRIGVIAPYRAQVELFKKLASK-LDTDLECNTVDQFQGRDKNLIIYSCSKTGGDFSDMERSREAEILEDQRRLTVAITRAKNKLILLGDIKCLEQYGPFRQLFKHIPD-----------RCRLKLEEGRMEFGWQRIQEDLVGLMDT-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .* . : . : :: : : : * : .: ** : : . ::..: . : **.::*.*:: .*: * *:::*. *: . . * :*.::**::*. : .: :: : . : ..: : * : .. . *: : . . . .: : ****.:* * **** :*.:* .: . . : .::***:***: * *:.:. * ::* *: . : . ***:. . : ..: . :.:* ** :: : :.: . . * :* * * : . * : :. . * :.: . . : .:. ...* .: * : . :* * :. . . : . :: .. :.:. * : :: : :.*.* : :*:.: : . : . * . . .::: .. . ** *::* :.: :..: ** *:****** .: ::::* * **:*: *******::::* : ::*** ::* :: : : . .. :*..**:* .. :* : **: *:***:*: * * ** . :*::*** ****:* . ** * .*:**: : :. :.. *::**** * *:* * * ..*:*..:.* : : : : * . .. . : *: .: . . :* ** : : :: :* . **::: ** *:. :..: : :* *.*::*****. :: * : . . . :*:: **:.**:**** ***::* : : :.. : .: . ", "identical_positions": 171, "similar_positions": 308, "identity": "10.91%" }, { "cls_id": "homologset.agr.SGD:S000001208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6H2-1", "uniprot_id": "G3V6H2_RAT", "id": "G3V6H2-1", "name": "Pre-mRNA-processing-splicing factor 8", "aln": "-------------------------------------------------MAGVFPYRGPGN----PVPG-------PLAPLPDYMSEEKLQEKARKWQQLQ-----------------AKRYAEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKT-EDPDLPAFYFDPLINPISHRHS--VKSQEPLPDDDEEFELPEFVEPFLKDTP-LYTDNTANGIALLWAPRPFNLRSGRTRRALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTVTEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQ-------LTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLP--SQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNP-KGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEG-EVYSADREDLYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PV0-1", "uniprot_id": "PRP8_MOUSE", "id": "Q99PV0-1", "name": "Pre-mRNA-processing-splicing factor 8", "aln": "-------------------------------------------------MAGVFPYRGPGN----PVPG-------PLAPLPDYMSEEKLQEKARKWQQLQ-----------------AKRYAEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKT-EDPDLPAFYFDPLINPISHRHS--VKSQEPLPDDDEEFELPEFVEPFLKDTP-LYTDNTANGIALLWAPRPFNLRSGRTRRALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTVTEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQ-------LTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLP--SQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNP-KGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEG-EVYSADREDLYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P2Q9-1", "uniprot_id": "PRP8_HUMAN", "id": "Q6P2Q9-1", "name": "Pre-mRNA-processing-splicing factor 8", "aln": "-------------------------------------------------MAGVFPYRGPGN----PVPG-------PLAPLPDYMSEEKLQEKARKWQQLQ-----------------AKRYAEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKT-EDPDLPAFYFDPLINPISHRHS--VKSQEPLPDDDEEFELPEFVEPFLKDTP-LYTDNTANGIALLWAPRPFNLRSGRTRRALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQ-------LTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLP--GQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNP-KGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEG-EVYSADREDLYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4I2-1", "uniprot_id": "A0A8M2B4I2_DANRE", "id": "A0A8M2B4I2-1", "name": "Pre-mRNA-processing-splicing factor 8", "aln": "-------------------------------------------------MAAPFPYRGLPG----PMPPGVPPPPPAVAPVPDYMTEEKLQEKARKWQQLQ-----------------AKRYSEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGTMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQMELDPDEDSSVTDWLYEHQPLKDTTKYVNGTTYRRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKT-EDPDLPAFYFDPLINPISHRHS--VKSQEPLPDDDEEFELPEYVEPFLKETP-LYTDNTANGIALLWAPRPFNLRSGRTRRAIDVPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLSKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAPGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSESWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAIYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETAEGECNVMLESRYEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDTATESAHPIRLYCRYIDRIHIFFRFSADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTIQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKFWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGAKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQ-------LTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGTSPPDNPQVKEIRCIVMVPQWGTHQTVHLP--NQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKVMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNP-KGYLPSHYERVQMLLSDRFLGFFMVPGQVSWNYNFMGVRHDPNMKYDLQLANPKEFYHEVHRPSHFLNFASLQEG-EIYNADREDMYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8U0-1", "uniprot_id": "A1Z8U0_DROME", "id": "A1Z8U0-1", "name": "Pre-mRNA-processing-splicing factor 8", "aln": "MSIPPYMIPQNAWAAQLMAQQAYAAAHAQQAQLHAQQQMANQIQQIPPPGAPLPPAGGHTNGIPIPVGGQGPGLGQIPTPKPDILTEEKLQEKALKWQHLQ-----------------SKRFAEKRKFGFVDTQKEDMPPEHIRKIIRDHGDMTSRKYRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVQVLYHITGAITFVNEIPWVIEPVYIAQWGTMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNVLDVEPLEAIQIELDNDEDNAVYKWFYDHRPLVDT-QFVNGTTYRKWNLSLPQLATLYRLANQLLTDLVDNNFFYLFDPKSFFTAKALNMAIPGGPKFEPLIKDHNVGDEDWNEFNDINKVIIRQPIRTEYRIAFPYLYNNMPHFVHLSWYHTPNVVYIKT-EDPDLPAFYFDPLINPISHRNAN-SKIQEPLPDDDEDFTLPDDVQPFLQDTP-LYTDNTANGIALLWAPRPFNMRSGRSRRAIDVPLVKCWYKEHCPPGHPVKVRVSYQKLLKYYVLNALKHRKPKPQKKRYLFRSFKATKFFQTTTLDWVEAGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREILRLTKLIIDSHVQYRLNNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAPGWRVWLFFMRGITPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELRASVMHDIVDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPIPIENMILRYVKMKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYISPEEAVAIYTTTVHWLESRRFAPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLIPVYEVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPSDTEPPPLLAYKWCQGINNLQDVWDVGEGECNVLLESRFEKLYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFSSFITQYYGLVLDLLVLGLHRSSEMAGPPQMPNDFLTFQDTVTETAHPIRLYCRYVDRIHLFFRFSAEEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTIGWESTFVSVYSKDNPNLLFNMSGFECRILPKCRTQNEEFTHRDGVWNLQNEITKERTAQCFLRVDDESLGRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEANAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRIRTEFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFPAYKWNVSRPSLLADTKDTMDNTTTQKYWLDIQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGCKTLIQQAMAKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNTERTKIILKPDKTTITEAHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSAQRQQIAEIEKQTKEQNQ-------LTATTTRTTNKHGDEIITSTTSNYETQTFSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFVTISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMPPQWGTHQTINLP--NTLPTHQYLKDMEPLGWIHTQPNELPQLSPQDITTHAKIMQENSNWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGSKNTDKGNNP-KGYLPSHYERVQMLLSNKFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHELHRTSHFLLFSNLEDGGDGAGADREDVYA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33334-1", "uniprot_id": "PRP8_YEAST", "id": "P33334-1", "name": "Pre-mRNA-splicing factor 8", "aln": "----MSGLPPPPPGFEEDSDLALPPPPPPPPGYEIEELDNPMVPSSVNEDTFLPPPPPPPSNFEINAEEIVDFTLPPPPPPPGLDELETKAEKKVELHGKRKLDIGKDTFVTRKSRKRAKKMTKKAKRSNLYTPKAEMPPEHLRKIINTHSDMASKMYNTDKKAFLGALKYLPHAILKLLENMPHPWEQAKEVKVLYHTSGAITFVNETPRVIEPVYTAQWSATWIAMRREKRDRTHFKRMRFPPFDDDEPPLSYEQHIENIEPLDPINLPLDSQDDEYVKDWLYDSRPLEEDSKKVNGTSYKKWSFDLPEMSNLYRLSTPLRDEVTDKNYYYLFDKKSFFNGKALNNAIPGGPKFEPLYPRE--EEEDYNEFNSIDRVIFRVPIRSEYKVAFPHLYNSRPRSVRIPWYNNPVSCIIQNDEEYDTPALFFDPSLNPIPHFIDNNSSLNVSNTKENGDFTLPEDFAPLLAEEEELILPNTKDAMSLYHSPFPFNRTKGKMVRAQDVALAKKWFLQHPDEEYPVKVKVSYQKLLKNYVLNELHPTLPTNHNKTKLLKSLKNTKYFQQTTIDWVEAGLQLCRQGHNMLNLLIHRKGLTYLHLDYNFNLKPTKTLTTKERKKSRLGNSFHLMRELLKMMKLIVDTHVQFRLGNVDAFQLADGIHYILNHIGQLTGIYRYKYKVMHQIRACKDLKHIIYYKFNKN-LGKGPGCGFWQPAWRVWLNFLRGTIPLLERYIGNLITRQFEGRSNE-IVKTTTKQRLDAYYDLELRNSVMDDILEMMPESIRQKKARTILQHLSEAWRCWKANIPWDVPGMPAPIKKIIERYIKSKADAWVSAAHYNRERIKRGAHVEKTMVKKNLGRLTRLWIKNEQERQRQIQKNGPEITPEEATTIFSVMVEWLESRSFSPIPFPPLTYKNDTKILVLALEDLKDVYASKVRLNASEREELALIEEAYDNPHDTLNRIKKYLLTQRVFKPVDITMMENYQNISPVYSVDPLEKITDAYLDQYLWYEADQRKLFPNWIKPSDSEIPPLLVYKWTQGINNLSEIWDVSRGQSAVLLETTLGEMAEKIDFTLLNRLLRLIVDPNIADYITAKNNVVINFKDMSHVNKYGLIRGLKFASFIFQYYGLVIDLLLLGQERATDLAGPANNPNEFMQFKSKEVEKAHPIRLYTRYLDRIYMLFHFEEDEGEELTDEYLAENPDPNFENSIGYNNRKCWPKDSRMRLIRQDVNLGRAVFWEIQSRVPTSLTSIKWENAFVSVYSKNNPNLLFSMCGFEVRILPRQR-MEEVVSNDEGVWDLVDERTKQRTAKAYLKVSEEEIKKFDSRIRGILMASGSTTFTKVAAKWNTSLISLFTYFREAIVATEPLLDILVKGETRIQNRVKLGLNSKMPTRFPPAVFYTPKELGGLGMISASHILIPASDLSWSKQTDTGITHFRAGMTHEDEKLIPTIFRYITTWENEFLDSQRVWAEYATKRQEAIQQNRRLAFEELEGSWDRGIPRISTLFQRDRHTLAYDRGHRIRREFKQYSLERNSPFWWTNSHHDGKLWNLNAYRTDVIQALGGIETILEHTLFKGTGFNSWEGLFWEKASGFEDSMQFKKLTHAQRTGLSQIPNRRFTLWWSPTINRANVYVGFLVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESIVFDICQILDGELDVLQIESVTKETVHPRKSYKMNSSAADITMESVHEWEVSKPSLLHETNDSFKGLITNKMWFDVQLRYGDYDSHDISRYVRAKFLDYTTDNVSMYPSPTGVMIGIDLAYNMYDAYGNWFNGLKPLIQNSMRTIMKANPALYVLRERIRKGLQIYQSSVQEPFLNSSNYAELFNNDIKLFVDDTNVYRVTVHKTFEGNVATKAINGCIFTLNPKTGHLFLKIIHTSVWAGQKRLSQLAKWKTAEEVSALVRSLPKEEQPKQIIVTRKAMLDPLEVHMLDFPNIAIRPTELRLPFSAAMSIDKLSDVVMKATEPQMVLFNIYDDWLDRISSYTAFSRLTLLLRALKTNEESAKMILLSDPTITIKSYHLWPSFTDEQWITIESQMRDLILTEYGRKYNVNISALTQTEIKDIILGQNIKAPSVKRQKMAELEAARSEKQNDEEAAGASTVMKTKTINAQGEEIVVVASADYESQTFSSKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKK----RDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFSELAGD-EELEAEQIDVFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .* *. *. ** : : : :*: ::* * . : : * :*****:****. *.**:.: :. **:.:******:***:******** **** ::* **** :***:**** * ****** :**.: ** ******** ************:****.* ::: ::***:.*:: ** ::* * .*:*: :** : : ***::*::*.: ** ::.****:. * ::.*.*::**** *:**..**** *********** :**:****.*:::*:* ***:**::***:***. *: *::.**:.* *:. *: * **::*** :***.* . : . ..:: :* **: . *:* : * ** :.::* :* *** .*: ** *:.*.* *: :* ****:******** **** *: *. ::* *::*:* **:** *.:****.***:****:**********.*.************.************:**:*** **:*:: **::*:***:**.**********::**: *:*****:******:*:*** ******:***:**.. :********* ..***** *:** *****::***::****** .: :.**.****:::::***** :**.**::****.*:*:***********:**********.***:* **:::* **:* *** *..:********:*** *:**: **********::* *****:: *:** *:.***.::::. *.***** *:*******:**:***:*:**** **:.*: * *** *:****.***:******::*.***::*****.** *.* :*: *.:: ***.*:*******************:*:*** ****:*:* ****.*** ******.::*:...*:. *:**: :: ****:************ *****:*********:***.*.*.**:****:*:*** ******:***:** .*::::***.: **:*: *:. .* ******: **:***:::*:* :*..:* :.**:*:**** ** :****:****:*:****:::**********:*:.*:* *:*:: **.:*******:******.*.*** ****: * * .:: :***:* :* **:***:.:*:*.:*.: :*..*:* ************:. ****:**.*:******:* *: ***:*** *.:**.*:*:*******:****.*************:* .*:*** *** ******.******:**:*::::***.::*** .**.**:********** ***** *****::*:**.*********.****:********:* *:* :****.: ::.*****:.:********* ****:******:* ********** * :*************:**::****:***:**.************************ *********:****************************:*:**::* ***.*:**:* ***:***********.*** : . ::*:**:**** :::* :.. *:* *:*:***:*******:.**.***********:*:*******:*.******::.****** * *.***::* .*****************.**:*.*. **:*.*.**.***.*:* ***********:*******::**.***.** :**:**:*****************.***********:**:**** ************.********:******.*: :**:***.*.:.::*:.*:::***********:*****. ********** *:****:.* : :*:** .* * :.:*:**::***:**.:* *::****::**:* ***:::***:**:***** :*.*** :**::**:* .*:.: *. *:* * :*:**:. ::::**:******.*** **: : *:** ::****:**: * .*:****:****: ***:: *:*.::** *. *:*:****: :*: ** * ::::. : : :* *******.:* ::..:::**:*:: :: .. * *: **** :*:**:** .*::** :*.* * :*: *:. :.*:***::: * *::*. ***.***. .: : .*::: . * ***:*:**. *** *: * . : *:: *:::", "identical_positions": 1400, "similar_positions": 608, "identity": "57.68%" }, { "cls_id": "homologset.agr.SGD:S000001209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AB31-1", "uniprot_id": "A0A8I6AB31_RAT", "id": "A0A8I6AB31-1", "name": "Cell division cycle protein 23 homolog", "aln": "MAANSSVVSVAAAATTVPGVSTVADFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALP--LSELQPPP-------PLTEEDAQDVDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDD-------------------------------------ETVDSLGPLEKGQVKNEALRELRVELSRKHQARGLDG-------FGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLS--------------------LPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD-PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQC--YIKYIQDIYSCGETVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRN----------------------------------------------------------------------QGETPTSDTPGTFFLPAS------------LSANNTPTRRVSPLNLSSVTP---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGZ4-1", "uniprot_id": "CDC23_MOUSE", "id": "Q8BGZ4-1", "name": "Cell division cycle protein 23 homolog", "aln": "MAANSSVVSVAAAATAVPGVSTVADFSDLQEIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALP--LSELQPPP-------PLTEEDAQDVDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDD-------------------------------------ETVDSLGPLEKGQVKNEALRELRVELSRKHQARGLDG-------FGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLS--------------------LPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD-PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKKALVKLAKLHEQLTESEQAAQC--YIKYIQDIYSCGETVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRN----------------------------------------------------------------------QGETPTSDTPGTFFLPAS------------LSANNTPTRRVSPLNLSSVTP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX2-1", "uniprot_id": "CDC23_HUMAN", "id": "Q9UJX2-1", "name": "Cell division cycle protein 23 homolog", "aln": "MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALP--LAELQPPP-------PITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDD-------------------------------------ETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDG-------FGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLS--------------------LPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD-PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQC--YIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRN----------------------------------------------------------------------QGETPTTEVPAPFFLPAS------------LSANNTPTRRVSPLNLSSVTP---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L8-1", "uniprot_id": "Q9I7L8_DROME", "id": "Q9I7L8-1", "name": "Cyclosome subunit 8", "aln": "------MAMQKFFSVLLPDVK--------RELRRGIIECS----KRGLLHSTKWLAEMHHGLADVH--IDNEAPDEDRTFSECQLEGIAPEEYSDYFLAKSYYDVREYDRAAHAVRNCESSVPRFLHFYSSYMAREKRRLD-------------------------------------STTDQANLHEPNQMR--DLADLLATLRMEYGKSRLDG-------YGIYLYGVVLKALNLNQAAEQMLVQAIRLVPMLWSAYLELSPLIMEKKKLLSLQ--------------------LGGHWMRHFFMAHTYLELYLNDDGLKIYEDLQASGFSKSIYLIAQMALVYHNKRDVDKAIELYQALLESD-PYRLDNVDTYSNLLFVKEMKTEMAQLAHKAVSINKYRPETCCVIGNYYSIRCDHQVAISYFQRALKLNPKYLAAWTLMGHEFMELKNTNAAIQSYRKAVEVNKRDYRAWYGLGQAYEIIKMHYYSLYYFKIAHQLRPYDSRMLVALGETYEKLDKCENAVKCYWKAIDVGDIEGIAMYKLANLHEKLGDHETAVHC--YIMYCEDERAA---TDKQSLYQGFITLANYYEKKGEYERAAYYAYKCLDSEDRKMEAKALLKTIDWKRNAEGQKKVKTSTAVANADTSSEDEMEWELQDVRVRVPITSIATTTTSTTTVAAESASSSSLISLRPDRNLIQGMRRSQSSRTSLTAPASGTTTTPSATAVTMSTEETPGTSGGPSNPPEQAPSDDNSSMEISSVSID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JHM5-1", "uniprot_id": "E1JHM5_DROME", "id": "E1JHM5-1", "name": "Cdc23 domain-containing protein", "aln": "------MAMQKFFSVLLPDVK--------RELRRGIIECS----KRGLLHSTKWLAEMHHGLADVH--IDNEAPDEDRTFSECQLEGIAPEEYSDYFLAKSYYDVREYDRAAHAVRNCESSVPRFLHFYSSYMAREKRRLD-------------------------------------STTDQANLHEPNQMR--DLADLLATLRMEYGKSRLDG-------YGIYLYGVVLKALNLNQAAEQMLVQAIRLVPMLWSAYLELSPLIMEKKKLLSLQ--------------------LGGHWMRHFFMAHTYLELYLNDDGLKIYEDLQASGFSKSIYLIAQMALVYHNKRDVDKAIELYQALLESASPYRLDNVDTYSNLLFVKEMKTEMAQLAHKAVSINKYRPETCCVIGNYYSIRCDHQVAISYFQRALKLNPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16522-1", "uniprot_id": "CDC23_YEAST", "id": "P16522-1", "name": "Anaphase-promoting complex subunit CDC23", "aln": "-------MNDDSQDKIIHDIRIQLRKAATELSRWKLYGSSKWAAEALAGLAEAIDVDQTHSLADESPLRNKQGVPKQMFEIPQNGFGLSETEYDLYLLGSTLFDAKEFDRCVFFLKDVTNPYLKFLKLYSKFLSWDKKSQESMENILTTGKFTDEMYRANKDGDGSGNEDINQSGHQRANLKMVSNEHESQSNISSILKEINTFLESYEIKIDDDEADLGLALLYYLRGVILKQEKNISKAMSSFLKSLSCYSFNWSCWLELMDCLQKVDDALLLNNYLYQNFQFKFSENLGSQRTIEFNIMIKFFKLKVFEELNGQLEDYFEDLEFLLQVFPNFTFLKAYNATISYNNLDYVTAESRFDDIVKQD-PYRLNDLETYSNILYVMQKNSKLAYLAQFVSQIDRFRPETCCIIANYYSARQEHEKSIMYFRRALTLDKKTTNAWTLMGHEFVELSNSHAAIECYRRAVDICPRDFKAWFGLGQAYALLDMHLYSLYYFQKACTLKPWDRRIWQVLGECYSKTGNKVEAIKCYKRSIKASQTVDQNTSIYYRLAQLYEELEDLQECKKFMMKCVDVEELLEGIVTDETVKARLWLAIFEIKAGNYQLAYDYAMGVSSGTSQEIEEARMLARECRRHM----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : : : .: ..*. : : . * *..: :*.:*:**... ::. . ** :** ::: :*: : . . . . .* . : . : .: *. ** **:*: . . * . :::: .: *..:*** : . . *. : * .** : : ** : .: *.: :: : * :* * .* . :: : :. ***:::::*:**:*:* . ::::: **: .*:::* ****:*.**** * :*: : **:***.*: : ", "identical_positions": 64, "similar_positions": 114, "identity": "8.31%" }, { "cls_id": "homologset.agr.SGD:S000001211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AFK4-1", "uniprot_id": "A2AFK4_MOUSE", "id": "A2AFK4-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "-------------------MVSTRLVLARTCTVFEGVLKWAPSTRAVLRPSHLL-LQASCRLLSVGIVDHAKHREPSGKKVLSEKKLKRHFVDHRRVLVRGGSGGSGMSCFHSEPRKEFGGPDGGDGGNGGHIILRVDQQVKS----LSSVLSQYQGFSGEDGGSKNCSGRGGATLYIQVPVGTLVK-------------------EGDKIVADLSNLGDEYVAALG-----------------------------------------------------------------------------GAGGKGNRFFLANDNRAPVTCTPGQPGQERVLYLELKTMAHAGMVGFPNAGKSSLLRAISNAKPAVASYPFTTLNPHVGIVHY-EGHQQVAVADIPGIIRGAHQNKGLGLSFLRHIERCRFFLFVVDLT---------LPEPWTQVDDLKYELEKFEEGLSERSHVIIANKIDLPQAR----ARLPQLQARLG-----------------QEAIGLSALTGENLEQLLLHLKELHDAHIEAELEQGRQPLRW---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AA18-1", "uniprot_id": "A0A8I6AA18_RAT", "id": "A0A8I6AA18-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "-------------------MVPTRLVLARTCTVFDSVLKWAPSTCAVLKPSQLLPLQASCRLLSVGIVDHAKHREPSGKKLLSEKKLKRHFVDHRRVLFRGGSGGSGMSCFHSEPRKEFGGPDGGDGGNGGHIILRVDQQVKS----LSSVLSQYQGFSGEDGGSKNCFGRGGATLYIQVPVGTLVK-------------------EGDEIVADLSHLGDEYVAALG-----------------------------------------------------------------------------GAGGKGNRFFLANDNRAPVTCTPGQPGQERVLYLELKTMAHAGMVGFPNAGKSSLLRAISNAKPAVASYPFTTLNPHVGIVHY-EGHQQVAVADIPGIIRGAHQNKGLGLSFLRHIERCRFFLYVVDLS---------LPEPWTQVDDLKYELEKYEEGLSERSHVIIANKIDLPQAR----AHLLQLQDRLG-----------------QEVIALSALTGENLEQLLLHLKVLHDAHIEAELEQGRQPLRW---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4K7-1", "uniprot_id": "MTG2_HUMAN", "id": "Q9H4K7-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "-------------------MAPARCFSARLRTVFQGVGHWALSTWAGLKPSRLLPQRASPRLLSVGRADLAKHQELPGKKLLSEKKLKRYFVDYRRVLVCGGNGGAGASCFHSEPRKEFGGPDGGDGGNGGHVILRVDQQVKS----LSSVLSRYQGFSGEDGGSKNCFGRSGAVLYIRVPVGTLVK-------------------EGGRVVADLSCVGDEYIAALG-----------------------------------------------------------------------------GAGGKGNRFFLANNNRAPVTCTPGQPGQQRVLHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHY-EGHLQIAVADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLS---------QPEPWTQVDDLKYELEMYEKGLSARPHAIVANKIDLPEAQ----ANLSQLRDHLG-----------------QEVIVLSALTGENLEQLLLHLKVLYDAYAEAELGQGRQPLRW---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLN0-1", "uniprot_id": "Q9VLN0_DROME", "id": "Q9VLN0-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "-------------------------------------MLFSTGKSFLARFSLNISRNAKPIGLIANYCQVASALRP--KKAKSTRKEAQYFSDAKRIRAIGGKGGDGCVSFLQLWCNERAGPDGGDGGHGGHVVFQASNDVRN----FNHVGSVLKAEEGEPGSSKDCHGKNAKHSVIKVPIGTVIRN------------------AQGQIVGDLGQADLMFVAARG-----------------------------------------------------------------------------GAGGKGNRFFTTDKETSPKVSEYGPRGEDLSYTLELRSMADVGLIGYPNAGKSTLLNALTRAKPKVAPYAFTTLRPHLGTVQY-DDHVQLTIADLPGLVPDAHRNKGLGIQFLKHAERCTLLLFVLDAS---------APEPWTHYEQLMHELRQFGGRLASRPQLVVANKLDVEEGQ----NNFEELQRRLQ-----------------NPVLGISAKMGHNLGQLLNSIRRGYDRHKDQPQESS---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38860-1", "uniprot_id": "MTG2_YEAST", "id": "P38860-1", "name": "GTPase MTG2, mitochondrial", "aln": "MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETLRPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSGAGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGS----LAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLS---------NKNPLNDLQLLIEEVGTLEK-VKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSK-----------------SQEWDCVPISALREENIDVLKKKMFKCARQSEFDK----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D4A3U1-1", "uniprot_id": "D4A3U1_RAT", "id": "D4A3U1-1", "name": "GTP-binding protein 10", "aln": "----------------------------------------------MVRCGCALLRKYG------------------------------NFIDNLRIFTKGGSGGMGYPRLG------------GEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALKGSKGKDCEVPAPVGVSVTD------------------ENGEVLGELNKEKDRILVAKG-----------------------------------------------------------------------------GLGGKLHTNFLP------------LKGQKRIIHLDLKVIADVGLVGFPNAGKSSLLSRVSHATPVIASYAFTTLRPELGKIMY-NDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQVKLHELMKQLQKPEDFLHLFEAKMIPEKAIEFQHIIPISAVTGEGIEELKNCIRESLDEQDDKENDAFHNKQLLSLQRSGSAS------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K013-1", "uniprot_id": "GTPBA_MOUSE", "id": "Q8K013-1", "name": "GTP-binding protein 10", "aln": "----------------------------------------------MVRCGCALLRKYG------------------------------NFIDNLRIFTKGGSGGMGYPRLG------------GEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALQGSKGKDCEVPAPVGISVTD------------------ENGQVLGELNKEEDRVLVAKG-----------------------------------------------------------------------------GLGGKLHTNFLP------------LKGQKRIVHLDLKVIADVGLVGFPNAGKSSLLSRVSHATPVIADYAFTTLRPELGKIMY-NDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAINKMDLPDAQVKLQELMKQLLSPEDFLHLFETKMIPEKALEFQHIVPISTVTGEGIAELKSCIRKALDEQDGKESDAHRSKQLLNLQSSS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1E9-1", "uniprot_id": "GTPBA_HUMAN", "id": "A4D1E9-1", "name": "GTP-binding protein 10", "aln": "----------------------------------------------MVHCSCVLFRKYG------------------------------NFIDKLRLFTRGGSGGMGYPRLG------------GEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTD------------------ENGKIIGELNKENDRILVAQG-----------------------------------------------------------------------------GLGGKLLTNFLP------------LKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMY-SDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHF7-1", "uniprot_id": "GTPBA_DANRE", "id": "Q6DHF7-1", "name": "GTP-binding protein 10", "aln": "----------------------------------------------MVWTSRICFRKYG------------------------------NFVDNVRLYVRGGTGGMGLPRLG------------GHGGDGGDVWVVAKKDTRLKQIKDKHPDKRFIAGVGSNSSIQALRGAKGEDVEVFAPTGISVTS------------------DHGRMLGELNREGDKLLVAKG-----------------------------------------------------------------------------GRGGSPQSGFLP------------NKGQTRNIRLDLKLIADFGLVGFPNAGKSSLLTALSHAKPKIANYPFTTIKPEIGKVMY-DDHKQVSVADLPGLIEGAHVNKGMGHKFLKHVERTKQLMFVVDVCGFQLASKTPFRSAFETVLLLSKELELYKEELLSKPAILVINKMDLPEAQSHFQELEAQLENQGESIHLFSEDVIPKSLMHFTHIVPVSAMTGHGLPLLKSLIRQSLEEQDTIDTEAQRSQKILELRREIPSSSIPSWGLPQPT-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7M2-1", "uniprot_id": "GTPBA_DROME", "id": "Q9I7M2-1", "name": "GTP-binding protein 10 homolog", "aln": "----------------------------------------------MVQIFKFLLKSSKSTGRAH---------------------FRPTFLDTLRLAVRGGHGGNGLPKYG------------GVGGQGGCVYLVAKEGLTLRKVVQGLKDKRVAASSGEDSSKASIFGRRGADQRIEVPVGVQVYD------------------DQQKLIADLDEHEATCIVAGG-----------------------------------------------------------------------------GTGGCTATNFLG------------RPGENRTVNLDLKLIADVGLVGFPNAGKSTLLKAVSNAKPKIAAYPFTTIRPQIGTIEY-RDLRSITVADLPGLIEGAHANFGMGHKFLKHIERTRLLVFMVDIFGFQLSPKHPHRDCLANVYALNKELELYDPSLLEKPSVLLLNKMDKEGAHEIFTKVKPLVSDLASGLEQCPEELRPKQVLNFDSIVPISAMNSSKITQVKSQLRRTLVRLAEKQFLADEDQVKEKLRQRVGVVG------PKIT-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : .* ** * * ** ** : . . . . * . * . : .* * : : . *. .: * * ** * * ::*: :*. *::* ******::* ::.* * :. : ***: * :* : . .::**:**:: .* : *:* **:* ** ::::* * *: : : : **:* : : . . : : ", "identical_positions": 58, "similar_positions": 61, "identity": "9.95%" }, { "cls_id": "homologset.agr.SGD:S000001212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTF0-1", "uniprot_id": "E9PTF0_RAT", "id": "E9PTF0-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELRLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIRFLVLDEADRLLEQGCTDFTADLETILSAVPAR--RQTLLFSATLTDTLKELQGLATN--QP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALARFKSSTYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEEIKQQLAEL--AVEEAQVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVEQTLRQQKAGSTGRRSRPPRPRP-QEPARAEAQN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4FZF3-1", "uniprot_id": "DDX49_MOUSE", "id": "Q4FZF3-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAEIGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPAR--RQTLLFSATLTDTLKELQGLATN--EP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEQIKQQLAEL--VVEEAEVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVGQTLRRQKAGSTVRRSRPPRSRP-QEPAQAEAQD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6V7-1", "uniprot_id": "DDX49_HUMAN", "id": "Q9Y6V7-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFS-IKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR--RQTLLFSATLTDTLRELQGLATN--QP----FFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLVHAIEEQIKKKLEEF--SVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPD------------------------LEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQGLV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38719-1", "uniprot_id": "DBP8_YEAST", "id": "P38719-1", "name": "ATP-dependent RNA helicase DBP8", "aln": "-----MADFKSLGLSKWLTESLRAMKITQPTAIQKACIPKILEGRDCIGGAKTGSGKTIAFAGPMLTKWSEDPSGMFGVVLTPTRELAMQIAEQFTALGSSMNIRVSVIVGGESIVQQALDLQRKPHFIIATPGRLAHHIMSSGDDTVGGLMRAKYLVLDEADILLTS---TFADHLATCISALPPKDKRQTLLFTATITDQVKSLQNAPVQKGKPPLFAYQVESVDNVAIPSTLKIEYILVPEHVKEAYLYQLLT--CEEYENKTAIIFVNRTMTAEILRRTLKQLEVRVASLHSQMPQQERTNSLHRFRANAARILIATDVASRGLDIPTVELVVNYDIPSDPDVFIHRSGRTARAGRIGDAISFVTQ-RDVSRIQAIEDRINKKMTETNKVHDTAVIRKALTKVTKAKRESLMAMQKENFGERKRQQKKK---------------------------------------------------------------QNDGKSLRS-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07886-1", "uniprot_id": "DDX49_DROME", "id": "Q07886-1", "name": "Probable ATP-dependent RNA helicase Dbp45A", "aln": "MQRKEANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLADHLTGC--DTFS-FDNLKYLVVDEADRMLNG---DFDESLSIIERCLPKT--RQNLFFSATMKDFIKESSIFPIAS-----DCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEH--PIDQRMVERIFMQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEPAASEEGKALLQDERFKSVDSARFEKKGKGRSRATQEDTPTKPLKRLNKEKPVAQKGRADVKKDKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * **.:. : :. .*.:* *** ** *:**:* ******** **. *:* : **:* . * :*****:*** **:*** . *..:.:: .:: ** . : :: .* ::**.::* *****.*: .. :*.. : . ::**:**** :* * * .:* **.*:*:**:.* ::. . . : . * . *. .*:* .: :: * . : :: *: . :**.* .::* *:::.. ..**. * *:** :* :*::. * *******:******:*::*:*: * *. :*** ******** * :*::. *: : ***:.*: :: * : : : : :*. .:**. : :: .*.*: . ::* : * : ", "identical_positions": 139, "similar_positions": 139, "identity": "25.93%" }, { "cls_id": "homologset.agr.SGD:S000001213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC44-1", "uniprot_id": "B1WC44_RAT", "id": "B1WC44-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMTESVD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGTVPCRYKSSQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSIVR--DLKRNAGAGVISKKHTLGEVWIQKTSEMDT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMKSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDREDMDT--------------DDERQYQDFLEDLEEDETIRKNVNIYRDS--TVPV-ESDTD---DEGAPRISLAEMLEDLRISQ--DATGEEGASMMS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L48-1", "uniprot_id": "NMD3_MOUSE", "id": "Q99L48-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESIE--------HSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTVR--DLKRSAGAGVISKKHTLGEVWIQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDRENMDT--------------DDERQYQDFLEDLEEDEAIRKHVNIYRDA--TIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMMS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96D46-1", "uniprot_id": "NMD3_HUMAN", "id": "Q96D46-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESTD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQ--DIKRAAGAGMISKKHTLGEVWVQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDT--------------DDERQYQDFLEDLEEDEAIRKNVNIYRDS--AIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMLT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BLF0-1", "uniprot_id": "NMD3_DANRE", "id": "Q5BLF0-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMQAPPS--------SSHGNILCCTCGVPIPPNP-ANMCVSCLRTQVDISEGIPKQVTIHFCRQCERYLQPPGSWVQCALESRELLALCLKKLKASMSKVRLIDAGFLWTEPHSKRIKIKLTIQKEVMNGAILQQVFTVEFVVQGQMCEDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKHKLHQNTVRIKEIHEGIDFYYATKQHAQKMVDFLQCTVPCRSKASQRLISHDVHSNTYNYKSTFSVEIVPVCKDNVVCLSPRLAQSLGNMGQVCVCVRVTSSIHLIDPNTLQIAEVDGSTFWRHPFNSLCSPRQLEEFIIMDIDIIR--DQRLGAGAGLKSNKHTLAEVWVQKTSEMDS-SHQYHCRTFMGHLLNIGDLVLGFDFANANINDEFLNKMNPQHVPDVVLIKKSYDRMKRARKRVWKLKEMDREKDAADT--------------DDERQYTEFLEDLEEDEMLRKNINIFRDAS-KIPVEESDTD---DDGAPRISLAEMLEDLSLS---DATGGEGADMMTD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46050-1", "uniprot_id": "O46050_DROME", "id": "O46050-1", "name": "60S ribosomal export protein NMD3", "aln": "MDHEYVGVSPLGAADGKGAGSNAVILCCECGVAIQPNP-ANMCVTCLRNHVDITENIPKQAVLHFCRNCERYLQPPNEWIQAALESRELLAICLKKLKG-LKEVKLVDAGFIWTEQHSKRIKVKLTVHGEIIGGTMLQQVFVVEFTVQNQMCNDCHRTEAKDFWRCLVQVRQRAENKKTFYYLEQLILKHKAHENTLGIKPEHGGLDFFYANDNHARRMVDFLLTMVPGKVTTSKRLISHDIHSNNYNYKYNWSVEIAPVSKDSAVCLSKKLRHQLGNLSPLVLVNRVSSSIHLIDPLTAQIAELTSQVYFRAPFEAVCNPKQLVEYVVMDIDVIMEKDRKTYPGQGQVSFKHALCDIWVVRASELGINDNPIHTRSHLGHLLKVGDSVMGYNTGEANINDLEFDKLSSDEIPDVILVRKHYDRQTRLSQRVWKIKHLA--AEATDE--------------RSKYDYHEFLDDLEENEDIRGQVNIYRDTN-KTIPIEVQAA---GGDVPQITLEEMLEDMTLECADDEMGEEGGADDTEPQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38861-1", "uniprot_id": "NMD3_YEAST", "id": "P38861-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEFTPIDPHQH------QNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVDITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKG-LTKVRLVDASFIWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQIRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVVPIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLCSKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTG-----------ISRGNRVLADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYVPDVVLVKKLYQRKSK-KSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFLQELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMT--LEDGVENTPVESQQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :*** **..* .. :* *:: ***::.:*::. : **::*:*::*** *::. ********:**:::*. :.:*:*:**.*:*** **:*:::***:: * : .:::**.* *:: * * ** * :.: *:. :*:**:. :*:** :*******: * :*: *. : *:**:*: .:** :*::** ** : . *:.***:* *:. .** .:****.*:.**. * *. :* :.:**:. . : :::.:::::** * * *:: ..:: **:::. ** *::::: . ::.* :: : ::*::. .: . *:.:* : : ** *:*: .:.* *. .: :. : :***:*::* *:* .: * **:*.: . * : :* **::***: :* :*:::: * : . ..*:*.: *:*::: * *. : ", "identical_positions": 151, "similar_positions": 191, "identity": "27.81%" }, { "cls_id": "homologset.agr.SGD:S000001214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Y5-1", "uniprot_id": "ATG7_RAT", "id": "Q641Y5-1", "name": "Ubiquitin-like modifier-activating enzyme ATG7", "aln": "----MGDPGLSKLQFAP-FNSALDVGFWHELTQKKLNEYRLDEAPKDIKG--YYYNGDSAGLPTRLTLEFSAFDMSAPTPARCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVGLDQRLSPKQIQALEHAYDDLCRTEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKLTVGVYDPCNLTQHPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNASGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEELIDSHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPAD-LGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEQEGFTFLAKVFNSSHSFLEDLTGLTLLHQETQ--AAEIWDMSDEETV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D906-1", "uniprot_id": "ATG7_MOUSE", "id": "Q9D906-1", "name": "Ubiquitin-like modifier-activating enzyme ATG7", "aln": "----MGDPGLAKLQFAP-FNSALDVGFWHELTQKKLNEYRLDEAPKDIKG--YYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPAD-LGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQ--AAEIWDMSDEETV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95352-1", "uniprot_id": "ATG7_HUMAN", "id": "O95352-1", "name": "Ubiquitin-like modifier-activating enzyme ATG7", "aln": "MAAATGDPGLSKLQFAP-FSSALDVGFWHELTQKKLNEYRLDEAPKDIKG--YYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQ--AAEIWDMSDDETI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38862-1", "uniprot_id": "ATG7_YEAST", "id": "P38862-1", "name": "Ubiquitin-like modifier-activating enzyme ATG7", "aln": "----MSSE--RVLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDG-----IKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYS------------KWVCILDADDEIVNYDKCI------IRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVP-DLIDFKLLIIR----QNEGSFALNATFASIDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDC---GKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKL----VNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSS---------------------------KQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSG------------SETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHP-LYLEEISGLSVIKQEVERLGNDVFEWEDDESDEIA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *.:** *.* **..*::**:: **: :**.: : :. :* .:. . * * :*: . :. * *::.* *.*: **. **:*:*.* * * ** ::: .*::::*******:****: *.: *.* * * : : * : :: *. :: * : :*. * *.. .:.: *...: : *. :*** : : . .: ..::: :* *. ..: . * *: : * *. ***:* :* :.**:*:** :** ::*:.********* **::* *:** : ..* ********** *:*:*:.****::*****..:********.**:**** ***** ** *::*** ::* *.::**** ** : *. * ::*.::*. **..**::***:*:*******:::: :.* *********:::***** :. :.. :******:***** ** ****** ***:***:*::*.:******.*:** .* . .* ** :******** .*. : : *:::*.***.**:: : *: *: *.:: . :**:::**::::**.: . :::: .*:*: ", "identical_positions": 253, "similar_positions": 206, "identity": "35.58%" }, { "cls_id": "homologset.agr.SGD:S000001215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921G8-1", "uniprot_id": "GCP2_MOUSE", "id": "Q921G8-1", "name": "Gamma-tubulin complex component 2", "aln": "MSEFRIHHDVNELLSLLRIHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQFLQQNAKERAELAASAATSNTTS-FSIPVAASKMSTQELEELRKQLGSVSTGSTLQQSLELTRKMLRDKQNKKNSGQPLPVFPAWVYERPTLAGDFLIGSGLSSDTVLPIGTLPLASQESAVVEDLLYVLVGVDGRYITAQP---------LAGRQNRTFLVDPNLDLSIRELVNRILPVAASYSTVTRFIEEKSSF-EYGQVNHALAAAMRTLVKEYLILVTQLEQLHRQGLLSLQKLWFYIQPAMRTIDILASLATSVDKGECVGGSTLSLLHDRSFNYTG-DSQAQELCLYLTKAASAPYFEILEKWIYRGIIHDPYSEFMVEEH----ELRK-EKIQEDYNDKYWDQRYTVLPQQIPSFLQKVAGKILSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIE---------KAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQ-GDFFVHFMDLTEEELRKPVEDIILTRLEALLE--LALRMSTANTDPFKDDLKIELMPHDLITQLLRVLAI--------ETKQEKAMTHADPTELTL---------------------------SGLEAFSFDYMVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHALH------SAKWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCMLTN-PELLKVFSKLMSVCVMFTNCMQKFTQSMKLDSELGRLTLDQGSVQGPPTETERIEDRPRKELTRKHLSEHVDAPQLASGFEATINNFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYAERLERLSAERSQKAAPQVPVPRGPSAPAPRVAIPAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSJ2-1", "uniprot_id": "GCP2_HUMAN", "id": "Q9BSJ2-1", "name": "Gamma-tubulin complex component 2", "aln": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTS-INVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAWVYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQP---------LAGRQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSF-EYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTG-DSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEH----ELRK-ERIQEDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIE---------KAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQ-GDFFVHFMDLAEEELRKPVEDITPPRLEALLE--LALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAI--------ETKQEKAMAHADPTELAL---------------------------SGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLH------SAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTN-PELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTLEHSTVLGLPAG---AEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVTAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYP7-1", "uniprot_id": "GCP2_DROME", "id": "Q9XYP7-1", "name": "Gamma-tubulin complex component 2 homolog", "aln": "MYALLVFVERYSECKPVSESSSSTSLSAMGLPHGNKTSDVNSAAGSVPTTLAIASTSTILTTSQNVSGSTR--------------LSLTQSQDFPTSTPVNCKKATESDTTPVVFVRRGPMDRNRGAGKDERNDLSVIKERVLNAVSDQSLSGYRSVTNKTGNSPKSMPNDLVTLTDVPDEYRTHLLWEYYKVDGDKVP---RAEIAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISA---VGLAKYDTDFDIHTHLDRSLTHQVREILPLASYFMGVQKIIAATD---GLGQVMNSLNEALQELTHDFYLIIVQAEQELRHNRLTLQKLLYYLQPTMWVMHEVWSSLVIIQLSDSRDAEVLTYLHERIKRLEG-NKDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDN----EVIHRDELPEHYSDDYWERRYTLRDEQIPSFLAKYSDKILRTGKYLNVIRQCGKRVMPTQEMNLEFDPTSERHVSVIN---------DAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQ-GDFTMQFMDACEDELTKNVDHVLPMTLENLLG--LTLRISSARNDPYKDDLHCELLPYDLVTQMSKIMKK--------EEN------WQAQPRLDL---------------------------SGLECFAFTYEVKWPCSLVLNHISISKYQMLFRQLFYCKHVERQLCKIWKENSIARQFEPQ------AASLYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSHLNRSIFKLCKICLKYCEFIQ-ITQRYFQDAELRSMVRDS-------------ADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQINSMAKKNTADCFMNLVHRINFNAFYTDQMDKMCVEDAIG-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS91-1", "uniprot_id": "Q9VS91_DROME", "id": "Q9VS91-1", "name": "Gamma-tubulin complex component", "aln": "---------------------------------------------------------------------------------------------------MNSDKSESDFANKVRFHLSK-------------DELERQMRKIHDRE--ESVDEKMRPSGSENSGHNCNTSSSSSLPRQESWIFES--VGGYFLAN--------ENLAKMSLPCQEQLLMRDLIYAFSGVPSAYVKPDIQIDQISEMSAVDIAKIRFRLKKTFTGAFRALANETLPLIGYYISVQSYIEETNMSPNCGRTRLTLATALSDQLQDYYDLQSKLETDLQDKKLDLKDLVRQVRPWLPILKTFSNMASSAR-GNLTSAQVLTLLDQFYRDLKDTDIDLKERVNKILTSTSRAYMKIVQLWMQKGVLFDTQHEFFVEDTEPSSTMSSTLLAPEKCCHAYWAERYRLLPDRLPGFLLSQADDIFLAGKYLNILRQCN-VSLKLLQRPLAYSQGDLGHEEIIK---------TSYELPAHKFLKVLVEEHNLPLHIRNLKSYFLLQE-EGFSETFLHKCHEYLKYNVERLIPEKLQTLLA--ETLHKS---NDFIKDNVRCQLKVCDVATLLGRQHKAQRAVEDEEEEEKESCSEQDPPEVLNL---------------------------YGYEALALGYETKWPLSFIIYPELLEQLQMLQRVLFFLHYVKHHLTVLWQS-----PCEGT------GLQLTNRSGKLRHRMLMCMLSLENHIIQDITEPRWQSLTLTVDKAKCIDEVLNKLESTVEECLRLGLLPTANTFVKSLYTLGHVCLNFCDFVE----------------------------------------SSIGEKSTKELEQEVVEYEEEFKSFLTSILELVSQLAKTKDIAERDSCKQLLKRLGELIEFSDLDKDQIASNI-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38863-1", "uniprot_id": "SPC97_YEAST", "id": "P38863-1", "name": "Spindle pole body component SPC97", "aln": "-----------------------------------------------------------------------------------MEIKEVDDRAELLRYTNNIPLLGKLVNHQPLWSTNP--------------KLKSFSLEKISAPDQRRVQEALVVKDLLN---VLIGLEGTYIRYFNDYEPSDPETPIEFKIAKKMDPSFKTFSRRIVRYGKQYMILTRAYEKWSDTSFGMVLQRF-----------AYEIRRFLEDVYLKTLVERLERDFNKVPNFSIRELEQIINETEVNKQMELLYNIYEEIFREIEERRTNQSSQEDFNN----FMDSMKNESSLHLRLMVAFDTTVYPVP----KGGAILKIFQQKILENLG-DRSSVMFLKKLLNNISQDYCTMLYEWLTQGILNDPYQEFMTYDDLEGKTDNIFDTRDRAWDTQYFIRKDVLLRDCDSEEDKNLLFKMLRTGILLKVVRASLQIPTIPSNSSDITIQEINDFADLMEGSNLELYVDKCYSRANEIFLKLFFQGYDLINVLKHLQQIFLGYQSGHNVLKFLTKNMGELTKHYRNDNNANYDKLLQNFELERQSENPNNLMRQLLMIQFDTETLPQVLSHYLQIYPEVPENNSANDDSDPLMHANNFKNMNAILFDELSKERTGAYHGSNLELYTPKSAIYHLKFDINIPYPLNIIISRTCMIKYQIILRYQLVLQYHSRLLDETWMDLNKTPSWKYRGYSHTVKRRIVRATRVLHAKMNHFIKTIMEYFNQNVIDKEVYSLEKCYRNPTLAVAIQNELEGGLTNIMTNRCLSD---LIPLQLQIFDIVYKFCKFIKSMRAKLCQLDP------------------------VLYEKHKSGMMKTLNEGYRTNNGGQEDVGYQEDAALELIQKLIEYISNASSIFRKCLINFTQELSTEKFDFYDSSSVDAAGIERVLYSIVPPRSASASSQR------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .*. . . :. . . : : :: :: . : * . : . . : * . : : .: . * . :..: : : . . .. *. :.: . : . : : * :: *: :*:: * **:. : . *: .: : : . . .:: :* *:::* . . . :: .: . . :*..:. :* :: :: :* : *: * : ** : * .: :: : :: : : : . : : . : : :* .::: : : *:: * : :: .: * * . : *: :* : .: :: :: : : . : . : : *. : : : : . :: . . : . : . . . : . :. . : ", "identical_positions": 32, "similar_positions": 166, "identity": "3.28%" }, { "cls_id": "homologset.agr.SGD:S000001217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGN--PDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGN--PDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGN--PDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGN--SDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGN--SDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGN--SEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGN--PEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVKRAVKYVNEFLAPALCNQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGN--PEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYPVVSIEDPFDQDDWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGN--KEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00925-1", "uniprot_id": "ENO2_YEAST", "id": "P00925-1", "name": "Enolase 2", "aln": "-------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : **.: **********:* * * **: ********::****:** ** .: **.* .** :*. :.. : . :.* :* :*.:::.:*** ****:*********:*..:*.*.:: :***:*:*:*: . :**** :**:*******. **:***** *.** .* :**::*:**** **.: * ::* .* ******.**** .*.*:*: ** **: :: **:* *:***:: *:******. * :: :. :*. :*:.::: :*:******* :*.* :* : ..**:*.******** ** * .*:.:.*********:::*:: * : .**.***********:**.****** *********.******* **::**** :* . :**..*:: ", "identical_positions": 222, "similar_positions": 123, "identity": "44.05%" }, { "cls_id": "homologset.agr.SGD:S000001218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K211-1", "uniprot_id": "COPT1_MOUSE", "id": "Q8K211-1", "name": "High affinity copper uptake protein 1", "aln": "-----MNHMGMNHMEMHHHMGMNHTD---------------------DNITMPP-HHHPTTSASHSHGGGDS---MMMMPMTFYFDFKNVNLLFSGLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLLRKSQVSIRYN----------------------------------SMPVPGPNG-TILMETHKTVGQQ-----------------------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JK41-1", "uniprot_id": "COPT1_RAT", "id": "Q9JK41-1", "name": "High affinity copper uptake protein 1", "aln": "--------MRMNHMEMHH-MGMNHTD---------------------DNITMPP-HQHPTTSASHSH--------EMMMPMTFYFGFKNVDLLFSSLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLLRKSQVSIRYN----------------------------------SMPVPGPNG-TILMETHKTVGQQ-----------------------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15431-1", "uniprot_id": "COPT1_HUMAN", "id": "O15431-1", "name": "High affinity copper uptake protein 1", "aln": "-------------MDHSHHMGMSYMD---------------------SNSTMQPSHHHPTTSASHSHGGGDSS--MMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYN----------------------------------SMPVPGPNG-TILMETHKTVGQQ-----------------------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKH1-1", "uniprot_id": "F1QKH1_DANRE", "id": "F1QKH1-1", "name": "Copper transport protein", "aln": "-------------MDMSH--SHHHVE---------------------ETTMPSPASDDHGGHLTTSGNGHGDH--MMMMQMTFYFGYKNVELLFAGLVINTPGEMAGACIGVFLLAVLYEGLKIGREVLLRRNQVNVRYN----------------------------------SMPVPGSDG-TVLMETHKTVGQR-----------------------------MLSMAHFLQTLLHIIQVVVSYFLMLVFMTYNGYLCIAVAAGAGLG-YFLFSWKKAVVVDITEHCH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NE97-1", "uniprot_id": "M9NE97_DROME", "id": "M9NE97-1", "name": "Copper transport protein", "aln": "MDHAHHSAPGVDHSMHHDHVGMHHDHSGIPAATASPMDAASMFDLIPDTSDLQASHAGHAAHGAHNHGGGSGTGMEHMMPMAFHFGYN-ETILFSWWHIETVAGLIGSMIAIFLLALMYEGLKYYREYLFWKTYNLLEYRPVT----------------------GPQRNPEAPRIPSPAAAAPSPVQYVGEVVHKQP--------------------------PSMLSINHLLQTLLHVLQVTLSFLLMLIFMTYNVWLCLMVVLGAAVG-YFLFCWKKSVIVDVTEHCH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4AAE7-1", "uniprot_id": "D4AAE7_RAT", "id": "D4AAE7-1", "name": "Copper transport protein", "aln": "------------------------------------------------------------------------------MPMHFIFSDE-AVLLFDFWRVHSPTGMALSVLVVLLLAVLYEGIKVGKAKLLHKTLESLPTTTS------------------------------QQLILEPDQDSTGSRSTSDNRTRLR------------------------------WFLCYFGQSLVHVIQVVIGYFVMLAVMSYNTWIFLGVVLGSAVG-YYLAYPLLHMT--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VA22-1", "uniprot_id": "Q9VA22_DROME", "id": "Q9VA22-1", "name": "Copper transport protein", "aln": "----------------MDHHGVDASEGHVHHHASHGSPEPVPPSSGHEGHHSPEMNHHGNHGEHTKHGHHEGGAHDMSMAMFFHTGDS-ETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFREWLFSWDRKRLAGGRDQYNRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSPQAQSSLILTQHTHHHVQENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTFNVWLCVAVLLGAGVG-YYIFCAFRTN---VQEHCN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHS6-1", "uniprot_id": "Q9VHS6_DROME", "id": "Q9VHS6-1", "name": "Copper transport protein", "aln": "----------------MDHGSDDSTS----------------------------------------------TAKSCPMIMVFHAGHC-ERILWRGWVASTVTEFVLSALAIFLVSFLYEALKFLRQQLARREARRAS---------------------------------EQLAAEQRRKNEAPAAGGCCSEAPLAE------------------PREQTYWQRLFAS-SHIVQSLLNLLQIVISYLLMLIFMTFNYWLCLAVILGLGLG-YFFFGWNKKNP-DESECCP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38865-1", "uniprot_id": "CTR2_YEAST", "id": "P38865-1", "name": "Copper transport protein CTR2", "aln": "----------MDDKKTWSTVTLRTFNQLVTSSLIG----------YSKKMDSMNHKMEGNAGHDHSDMHMGDGDDTCSMNMLFSWSYKNTCVVFEWWHIKTLPGLILSCLAIFGLAYLYEYLKYCVHKRQLSQRVLLPNR------------------------------------------SLTKINQADKVS----------------------------------------NSILYGLQVGFSFMLMLVFMTYNGWLMLAVVCGAIWGNYSWCTSYSPEIDDSSLACH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * . ::: : : : : :: :: :** :* ::.: :*: ..:::** .*::* :: : * * * * ", "identical_positions": 15, "similar_positions": 31, "identity": "5.15%" }, { "cls_id": "homologset.agr.SGD:S000001219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3X946-1", "uniprot_id": "G3X946_MOUSE", "id": "G3X946-1", "name": "Flavin-containing monooxygenase", "aln": "---MGVKRIAVIGAGVSGLGAIKCCLEEG--LEPTCFEKKSDIGGLWKYEEIPKSG-----NLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHHSKMMEYLRMYARHFGLMK---HIQFQTNVCNIKKRPDFSSSGQWDVVVET-EEMQKTYIFDGIMVCSGHYTEKYFPLQDFEGISKFQG--SYLHTWEYKHPDNFVGKRVAVIGLGNSGADVAGEISRVADQVFLSTRQGAWIWNRVWDHGEPMDTTVFTRYNRAVQKICPRYIINRQMEKKLNGRFNHANYGLLPTHRILEQRTVLSDDLPNRIIIGKVKIKPNVKEFTSTSAIFEDGT-KENIDVVIFATGYKLSFPFLSDDSG-VLDNQYSMFKYVFPPELEKPTLAFIGILQPAGAILPTSELQSRWVVHVFKGIKKLPSRRAMIADINRKNHQIMAK------GSKKILQDHRRVTFVDYMDEIASEIGVKPNLLSLLLWDTKLAKEVFCGPCTSYQYRLQGPGKWDGARAAILTQRERMLKPLRTRVVKQS------HLSHLSWV------------KSACVVVF----FFISVVVIMHITSH----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBP5-1", "uniprot_id": "D3ZBP5_RAT", "id": "D3ZBP5-1", "name": "Flavin-containing monooxygenase", "aln": "---MGVKKVAVIGAGVSGLGAIKCCLDEG--LEPTCFEKRSDIGGLWKYEEISKSG-----NLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLLK---HIQFQTKVCSIKKRPDFSSSGQWDVVVET-GETQKTYIFDGIMVCSGHYTEKHFPLQDFEGISKFQG--SCLHSWEYKHPNSFSGKRVVVIGIGNSGADVAGEISRVADQVFLSTRRGAWVWSRVWDHGNPMDASLFTRYNRAVQKFCPRYLINRQMEKKLNARFNHANFGLLPQHRILDHRTVFSDDLPSHIITGKVKIKTNVKTFTSTSAVFEDGT-EENIDVVIFATGYKLAFPFLSDDSG-ILDSQYSMFKYVFPPELEKPTLAFIGIVQPAGAIIPTSELQSRWVVRVFTGLQKLPPKKAMMADIYRK-HQADKD------AIKNLKDSSRRVQFIDYMDEIASEIGVKPNLLSLLLWDTKLAKEIFYGPCTSYQYRLQGPGKWAGARAAILTQRERILKPLRTRVVKHSRA----SLSHLFWV------------KSVCVVSF----FFISVLVIMHLTSV----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A6T0-1", "uniprot_id": "D4A6T0_RAT", "id": "D4A6T0-1", "name": "Flavin-containing monooxygenase", "aln": "---MEVKQIAIIGAGVSGLGAIKCCLEEG--LEPTCFEKSNDIGGLWRYEETTE-------RPGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLMK---HIQFQTRVCRVRKRPDFSSSGQWDVVVEV-DGKQKTYVFDGVMVCSGHSTEKCLPLQDFAGISKFQG--KYLHSWEYRHPDSFVGKRVVVIGIGNSGADVAGEISHVAEQVFLSTRRGAWIWNRVWDNGNPLDTTLFTRYNRTIQKFYPTFLINRWAENKLNARFNHANYGLQAKHRFLSHQSIFSDNLPNHIITGRVLVKPNVKEFTPTSAIFEDGS-EEIVDNVVFATGYTFSFPFLDDSSK-ILDSEHTMFKFVFPPQLEMPTLAFIGILQPVGATIPTSELQSRWVTRVFTGLQKLPSQSNMMADINKRKRKMEKE------FVKSPRGIHR-VQYIDYMDEIASELGVKPNLLSLFLWDTKLAKEIFWGPCTPYQYRLQGPGKWAGARVAILTQRDRILKPLKTRVLKNCET----SSSSLFWV------------RYICAVIV----LFVPVLLILLVIYQ----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97872-1", "uniprot_id": "FMO5_MOUSE", "id": "P97872-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MAKKRIAVIGAGASGLTCIKCCLEEG--LEPVCFERSGDIGGLWRFQEAPEEG-----RASIYQSVVINTSKEMMCFSDYPIPDHYPNYMHNSQVLEYFRMYAKEFDLLK---YIQFKTTVCSVKKQPDFSTSGQWQVVTEC-EGKQQVDVFDGVLVCTGHHTDAHLPLESFPGIEKFKG--KYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMYYLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDGIDVVIFATGYSFAFPFLEDSVK-VVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKAREEMAKR------YVDSQR-HTIQGDYIDTMEEIADLVGVRPNILPLVFTDPRLALRLLLGPCTPVQYRLQGPGKWAGARKTILTTEDRVRKPLMTRVV-ERDS----SGGSLVTV------------RVLMLAVA----FFAVILAYF---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4C0-1", "uniprot_id": "FMO5_RAT", "id": "Q8K4C0-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MAKKRIAVIGSGASGLTCIKCCLEEG--LEPVCFERSDDIGGLWRYQENPEKG-----RASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNSQVLEYFRMYAKEFGLLK---YIQFKTTVCSVKKQPDFSTSGQWQVVTEH-EGKQQVDVFDGVLVCTGHHTDPHLPLDSFPGIEKFKG--KYFHSREYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKRGYPIDILLSSRITNYLSKICGSALKNRYMEKQLNQRFDHEMFGLKPKHSALGQHPTINDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDVVIFATGYSFAFPFLEDSVK-VVQNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKTREEMAKR------YVDSQR-HTIQGDYIDTMEEIADLVGVRPNLLSLAFTDPKLAFQLLVGPCTPVQYRLQGPGKWAGARKTILTTEDRIRKPLMTRVV-ERDS----SGTSLVTV------------RVLMLAVT----FLAVILAYF---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49326-1", "uniprot_id": "FMO5_HUMAN", "id": "P49326-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MTKKRIAVIGGGVSGLSSIKCCVEEG--LEPVCFERTDDIGGLWRFQENPEEG-----RASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLK---YIRFKTTVCSVKKQPDFATSGQWEVVTES-EGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKG--QYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVK-VVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKR------YVESQR-HTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVV-ERSS----SMTSTMTI------------GKFMLALA----FFAIIIAYF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZD07-1", "uniprot_id": "D3ZD07_RAT", "id": "D3ZD07-1", "name": "Flavin-containing monooxygenase", "aln": "---MAKKRIAVIGAGISGLGAIKCCLDED--LEPTCFERSDDIGGLWKFQKNPSEK-----MPSIYKSVTINTSKEMMCFSDFPIPDHFPNYMHNCKLMDYFRMYAEHFGLLD---HIRFKTTVRSVRKRPDFSVQGQWDVIVEA-DGKQESLVFDGILVCSGHHTDPHLPLKSFPGIEKFEG--CYFHSREYKSPEDYVGKRIIVVGIGNSGVDIAVELGRVAKQVFLSTRRGSWILHRVWNNGYPMDSSFFTRFNSFLQKLLSTEAVNKYLEKMMNSRFNHAHYGLQPQHRPLSQHPTVSDDLPNHIISGKVQVKPNVKEFRGTDVVFDDGTVEEKIDVVIFATGYSFSFPFLEDLIA-VTDNEVSLYKLMFPPDLEKPTLAVIGLIQPLGIVLPISELQSRWAVRVFKGLSKLPSVKIMNADMAQRKKAMAKR------YVKTVR-HTIQVDHIEYMDEIAALAGVKPNLLLLFLSDPLLAMEVFFGPCTPYQYRLQGPGKWDGARRAILTQRERIIKPLKTRITSEKSH----SAPGLFWI------------KMTLFGLA----FLVISLIYFSYICYEKRK------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AA53ECJ5-1", "uniprot_id": "A0AA53ECJ5_DANRE", "id": "A0AA53ECJ5-1", "name": "Flavin-containing monooxygenase", "aln": "----MVKRVAVIGAGSSGLAAIKCCLDEG--LEPVCFESSDDIGGLWRFREKPETD-----RCSIYHSLTVNTSKEMMCYSDFPVPDNFPNFMHNSLIVQYYRLYAEHFNLFE---HIHFQTTVRSVRQRPDFSVSGQWEVVTADRDGQVETHMFDGVLVCVGHYTQPIKPLSEFPGIDTFPG--TVIHSWEYKKPDQYIGKKVLIIGIGNSGGDIAVELSRTCEKTFLSTRKGSWVIGRMVEKGLPLDMMNISRVQDLMHCLIPRALVNWIGERSLNQRHDHKLYGLQPKHRILDHRPVINDDLPGRILVGELVLKPNVQTFHGSTVVFDDGSIEEKIDAVILCTGYDYKFPFLPDSLNSSADGGMKLYRRIFPPSLERPTLAIIGLLQTRGPIMPAAELQARWATRVIKGLNHLPSAEKMSKRIEKDIKPYLKS------HPCPKL-ASLQVDYIPYLDSIAKEVGACPNIAWLLMTDPALGLRVFLGPCTPYQFRLSGPGHWKGARQAILTQWERVAKPMKTRPIPEPSS-----FSLLFWLGLSG-------GGAVILAII----ALQKKIPLFMGIS-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5TZD3-1", "uniprot_id": "Q5TZD3_DANRE", "id": "Q5TZD3-1", "name": "Flavin-containing monooxygenase", "aln": "----MAKRVAIIGGGTSGLACIKCCLDEG--LEPVCFETSDDIGGLWRFKENPDLD-----QASIYHSLIINTSKEMMCYSDYPIPAHFPNYMHNSLIMEYFRMYAENFQLKR---HIRFQTRVLHVTPRPDFPHSGQWDVETESKDGLREKQVFDAVMVCTGHHCHPHLPLKDFPGIDTFKG--KFFHSRDYKNPEDWRGKRAVVIGIGNSGGDIAVELSRMAKQVYLSTRKGSWILNRVGDSGVPFDMMFNNRAVMWFLDSLPVKYRNKLGESRLNKRFDHKLYGLQPEHRIFSQHPMVNDDLPNRILSGTVSVKPNVQEFRGSSVVFEDGTVEDNIDLVVFATGYTFSFPFLSSHVIPVSNNKVSLYKFVYPPGLERSTLAVIGLIQPLGAIMPISEMQARWATRVFKGLCKLPSKNAMMKDIKAKEQAMTQR------YVAAQR-HTIQVDYIPYMDELAKQVGVRPSIPRLLLTDPRLAFKVIFGPCTPYQFRLHGPGQWEGARQAILTQWDRVVEPLKTRCTKEPQSQSF-SHSLIFSVSVAGLLSALYYGRASLQTFLENPSALLDKIRGFVPLPMPTQ-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K2I3-1", "uniprot_id": "FMO2_MOUSE", "id": "Q8K2I3-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "aln": "----MAKKVVVIGAGVSGLISLKCCVDEG--LEPTCFERTEDIGGLWRFKENVEDG-----RASIYRSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVISVKKRPDFASSGQWEVYTQS-NGKEQRTVFDAVMVCSGHHIQPHLPLKSFPGIERFRG--QYFHSREYKHPVGFEGKRILVVGIGNSAADIASELSKTAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMEQQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDIIVFATGYTFSFSFLEDSLVKVEDNRVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGLCSLPSETTMMADIVERNEKRVN-------LFGKSQSQILQTNYVDYLDELALEIGAKPDFVSLFFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQSSDSAP---VSFLLKILG----------------------LLAVVLAFFFQLQGF---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRI9-1", "uniprot_id": "FMO2_RAT", "id": "Q6IRI9-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "aln": "----MVKKVAVIGAGVSGLISLKGCVDEG--LEPTCFERTEDIGGLWRFKENVEDG-----RASIYHSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVISVKKRPDFASSGQWDVYVQS-NGKEQRAVFDAVMVCSGHHIQPHLPLKSFPGIERFQG--QYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVLSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSETTMMADIAERNEKRID-------LFGKSQSQILQTNYIDYLDELALEIGAKPDFISLLFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQTSASAP---VSFLIKVLG----------------------LLAIVLAFFFKLHGF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99518-1", "uniprot_id": "FMO2_HUMAN", "id": "Q99518-1", "name": "Flavin-containing monooxygenase 2", "aln": "----MAKKVAVIGAGVSGLISLKCCVDEG--LEPTCFERTEDIGGVWRFKENVEDG-----RASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVLSVRKCPDFSSSGQWKVVTQS-NGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKG--QYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRID-------LFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGPGQWEGARNAIFTQKQRILKPLKTRALKDSSNFS---VSFLLKILG----------------------LLAVVVAFFCQLQWS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50285-1", "uniprot_id": "FMO1_MOUSE", "id": "P50285-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSSDLGGLWRFTEHVEEG-----RASLYKSVVSNSSREMSCYPDFPFPEDYPNFVPNSLFLEYLKLYSTQFNLQR---CIYFNTKVCSITKRPDFAVSGQWEVVTVT-NGKQNSAIFDAVMVCTGFLTNPHLPLDSFPGILTFKG--EYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPIVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVFIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMVPTGETQARWVVQVLKGATTLPPPSVMMEEVNERKKNKHS-------GFGLCYCKALQTDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVKVTKTRTIQES--PS--SFETLLKLFS----------------------FLALLIAVFLIFL-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36365-1", "uniprot_id": "FMO1_RAT", "id": "P36365-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSCDLGGLWRFTEHVEEG-----RASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLR---CIYFNTKVCSITKRPDFAVSGQWEVVTVC-QGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKG--QYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERKKNKHS-------GFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQET--PS--TFETLLKLFS----------------------FLALLVAVFFIFL-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01740-1", "uniprot_id": "FMO1_HUMAN", "id": "Q01740-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MAKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSDDLGGLWRFTEHVEEG-----RASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLK---HIQFKTKVCSVTKCSDSAVSGQWEVVTMH-EEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKG--QYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPS-------WFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQES--PS--PFESFLKVFS----------------------FLALLVAIFLIFL-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3QMN6-1", "uniprot_id": "J3QMN6_MOUSE", "id": "J3QMN6-1", "name": "Flavin-containing monooxygenase", "aln": "----MGKKVAIVGAGVSGLAAIRCCLEEG--LDPICFERSIDVGGLWKFSSHAEEG-----RASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYITSFAQKKGLLR---YIQFETLVSSIKKCSSFLTTGQWVVVTEK-EGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFRG--KCLHSRDYKGPGAFQGKKVLVIGLGNSASDIAVELSRLATQVIISTRSGSWIMSRVWNDGYPWDMVYVTRFTSFLRNILPSFVSDWLYIKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPSRILCGMVTIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNTCVLPTTNEMMDDIDEKMGKKLK-------WFGQS--HTLQTDYITYMDELSSFIGAKPNIPWLFLTDPQLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWKRTVKPTRTRAVGEAQRPR--HLYDLLRMLF----------------------FPVFFLAVLLTFY-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R553-1", "uniprot_id": "M0R553_RAT", "id": "M0R553-1", "name": "Flavin-containing monooxygenase", "aln": "----MGKKVAIVGAGVSGLAAIRCCLEEG--LEPICFERSNDVGGLWKFSSHVEEG-----RASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYIKSFAQKKDLLR---YIQFETLVSSIKKCSSFLTTGQWVVVTEK-DGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFQG--KCMHSRDYKGPGDFQGKKVLVIGLGNSASDIAVEVSRLATQVIISTRSGSWVMSRVWNDGYPWDMVYVTRFASFLRNILPSFVSDWLYVKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPARILCGTVSIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNACVLPTTNEMMDDIDEKMGKKLK-------WFGQS--HTLQTDYITYMDELSSFIGAKPNIPWLFVTDPQLALEVYFGPCSPYQFRLMGPGKWDGARSAILTQWKRTVKPTRTRAVGEAQRPC--HLYDLLQMLF----------------------FPVFFLAVLLTFY-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60774-1", "uniprot_id": "FMO6_HUMAN", "id": "O60774-1", "name": "Putative dimethylaniline monooxygenase [N-oxide-forming] 6", "aln": "----MSKRVGIIGAGVSGLAAIWCCLEEG--LEPTCFERSDDVGGLWKFSDHTEEG-----RASIYQSVFTNSSKEMMCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLR---YIQFETLVSGIKKCPSFLVTGQWVVVTEK-DGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRG--NYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPFLDETIMKSRNNEVTLFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKCMFSSFFMFGQS--QTLQTDYITYVDELGSFIGAKPNIPWLFLTDPRLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWNRTVKPTRTRVVSEVQRPH--PFYNLLKMLS----------------------FPLLLLAVTLTFY-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97501-1", "uniprot_id": "FMO3_MOUSE", "id": "P97501-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MKKKVAIIGAGVSGLAAIRSCLEEG--LEPTCFERSDDVGGLWKFSDHIEEG-----RASIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHHSKLQEYITSFAKEKNLLK---YIQFETPVTSINKCPNFSTTGKWEVTTEK-HGKKETAVFDATMICSGHHIFPHVPKDSFPGLNRFKG--KCFHSRDYKEPGIWKGKRVLVIGLGNSGCDIAAELSHVAQKVTISSRSGSWVMSRVWDDGYPWDMVVLTRFQTFLKNNLPTAISDWWYTRQMNARFKHENYGLVPLNRTLRKEPVFNDELPARILCGMVTIKPNVKEFTETSAVFEDGTMFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGVFPPQLEKPTMAVIGLVQSLGATIPITDLQARWAAQVIKGTCTLPSVNDMMDDIDEKMGEKFK-------WYGNS--TTIQTDYIVYMDELASFIGAKPNLLWLFLKDPRLAVEVFFGPCSPYQFRLVGPGKWSGARNAILTQWDRSLKPMKTRVVSKVQKSCSHFYSRLLRLLA----------------------VPVLLIALFLVLI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQ76-1", "uniprot_id": "FMO3_RAT", "id": "Q9EQ76-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MKRKVAVIGAGVSGLAAIRSCLEEG--LEPTCFERSDDVGGLWKFSDHTEEG-----RASIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHNSKLQEYITSFATEKNLLK---YIQFETLVTRINKCPDFSTTGKWEVTTEK-NSKKETAVFDAVMICSGHHVYPHLPKDSFPGLNRFKG--KCFHSRDYKEPGTWKGKRVLVIGLGNSGCDIAAELSHVAQQVIISSRSGSWVMSRVWNDGYPWDMVVITRFQTFLKNNLPTAISDWWYMKQMNARFKHENYGLMPLNGTLRKEPVFNDELPARILCGTVSIKPNVKEFTETSAVFEDGTVFEGIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTTDLQARWAAQVIRGTCILPSVNDMMDDIDEKMGKKLK-------WFGNS--TTIQTDYIVYMDELASFIGAKPNILWLFLKDPRLAIEVFFGPCSPYQFRLVGPGKWSGARNAILTQWDRSLKPMKTRVVGGIQKPC--LYSHFLRLLA----------------------VPVL-IALFLVLI-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31513-1", "uniprot_id": "FMO3_HUMAN", "id": "P31513-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MGKKVAIIGAGVSGLASIRSCLEEG--LEPTCFEKSNDIGGLWKFSDHAEEG-----RASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLK---YIQFKTFVSSVNKHPDFATTGQWDVTTER-DGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKG--KCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRK-------WFGKS--ETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWPGARNAILTQWDRSLKPMQTRVVGRLQKPC--FFFHWLKLFA----------------------IPILLIAVFLVLT-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHG0-1", "uniprot_id": "FMO4_MOUSE", "id": "Q8VHG0-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCLDEN--LEPTCFERTSDFGGLWKFADTSEDG-----MTRVYRSLVTNVCKEMSCYSDFPFREDYPNFMSHEKFWDYLREFAEHFGLLR---YIRFKTTVLSVTKRPDFSETGQWDVVTET-EGKRDRAVFDAVMVCTGQFLSPHLPLESFPGIHKFKG--QILHSQEYRIPDAFRGKRILVVGLGNTGGDIAVELSEIAAQVFLSTRTGTWVLSRSSPGGYPFNMIQTR-WLNFLVRVLPSRFINWTHERKMNKILNHENYGLSIAKGKKPK-FIVNDELPTCILCGKVTMKTSVKDFTESSVIFEDGTTEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKIILYKRVFPPNLERATLAIIGLISLNGSILVGTEFQARWATRVFKGLCSIPPSQKLMAEATKTEQLIKRG------VIKDT--SQDKLDFITYMDELTQCIGAKPSIPLLFIKDPRLAWEVFFGPCTPYQYRLVGPGRWDGARNAILTQWDRTLKPLKTRIVPKSPEPT--SLSHYLIAWG----------------------APVLLVSLLLIYKSSHFLELVQGKLPRRFPPYRLLWYMPQNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4B7-1", "uniprot_id": "FMO4_RAT", "id": "Q8K4B7-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCLDEN--LEPTCFERSSDFGGLWKFAEASEDG-----MTRVYRSLVTNVCKEMSCYSDFPFHEDYPNFMSHEKFWDYLREFAEHFGLLK---YIRFKTTVRSVTKRPDFSETGQWEVVTET-EGKQDRAVFDAVMVCTGQFLSPRLPLESFPGIHKFKG--QILHSQEYRIPDAFRGKRILVVGLGNTGGDVAVELSGIAAQVFLSTRTGAWVRSRSSVGGYPLNMMQTR-WRNFLAQVLPSRFVSWNQERQMNKIFNHENYGLSIAKGKKPK-FIVNDELPTCILCGKITMKTSVKDFTESSIVFEDGTIEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKVILYKRVFPPNLERSTLAIIGLISLTGSILVGTEFQARWATRVFKGLCNIPPSQKLMAEAIKKEELIKRG------VIKDT--SQDKLDFISYMDELTQCIGAKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGRWDGARNAILTQWDRTVKPLKTRTVPKSQEPA--SLSRYLKTWG----------------------APVLIVSLLLIYKSSLFLELVQSKLQGRFSPSRILWYIPQNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31512-1", "uniprot_id": "FMO4_HUMAN", "id": "P31512-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCVDED--LEPTCFERSDDIGGLWKFTESSKDG-----MTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLK---YIQFKTTVCSITKRPDFSETGQWDVVTET-EGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKG--QILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK-FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRG------VFKDT--SKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPA--SMSHYLKAWG----------------------APVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1E9-1", "uniprot_id": "Q9W1E9_DROME", "id": "Q9W1E9-1", "name": "Flavin-containing monooxygenase", "aln": "-----MMSVCIIGAGTAGLCCARHSIANG--FETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPKEVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKK---HIKFDSYVIRVLQRKTKWQVLFKDLVTNK----IEFQYFDKVLVANGHYHTPNYS--QIPNMERFKG--QFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLT---------------------------------------------------------------------DIGQHSFFENVQQKPDVRELDEKGAFFVDGS-YQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQ-MMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEG------LRKRHAHMLGPKQIDYFTDLSQTAGVKN--------------------IKPVMTKLHNES-SKCFNENLLHFREDNFAILDDETFIKLN-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38866-1", "uniprot_id": "FMO1_YEAST", "id": "P38866-1", "name": "Thiol-specific monooxygenase", "aln": "MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYPEQKSDG------RVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKK-----NSQWEITSKD-ELRTTKSDFDFVIVASGHYSVPKLP-TNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEP------------------------------------------------------------------ASNQLKAKLIETVQTIDS--ADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMVEVFCKSLPITTTFDSNACG---------THNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDRLIDLR----NSSYTDKE--------ERNVLLAEHAQALKKKKAPYFLPAPHT-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*.* .** . . :: * .** * : . :* : * ::: :..: . . : . :: : * *.: * : : ** ::. * . : .: : . :*: ::: * ::* * :. *:: . :. * :: : : : .* :.: *** :.*: : * . : : : . .: .. : . :: ", "identical_positions": 28, "similar_positions": 81, "identity": "4.58%" }, { "cls_id": "homologset.agr.SGD:S000001224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJW3-1", "uniprot_id": "TX261_RAT", "id": "Q5BJW3-1", "name": "Protein TEX261", "aln": "MWFMYVLSWLSLFIQVAFITLAVAAGLYYLAELIEEYTVATSRIIKYMIWFSTAVLIGLYVFERFPTSMIGVGLFTNLVYFGLLQTFPFIMLTSPNFILSCGLVVVNHYLAFQFFAEEYYP----------------FSEVLAYFTFCLWIIPFAFFVSLSAGENVLPSTMQPGD----DVVSNYFTKGKRGKRLGILVVFSFIKEAILPSRQKIY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62302-1", "uniprot_id": "TX261_MOUSE", "id": "Q62302-1", "name": "Protein TEX261", "aln": "MWFMYVLSWLSLFIQVAFITLAVAAGLYYLAELIEEYTVATSRIIKYMIWFSTAVLIGLYVFERFPTSMIGVGLFTNLVYFGLLQTFPFIMLTSPNFILSCGLVVVNHYLAFQFFAEEYYP----------------FSEVLAYFTFCLWIIPFAFFVSLSAGENVLPSTMQPGD----DVVSNYFTKGKRGKRLGILVVFSFIKEAILPSRQKIY-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWH6-1", "uniprot_id": "TX261_HUMAN", "id": "Q6UWH6-1", "name": "Protein TEX261", "aln": "MWFMYLLSWLSLFIQVAFITLAVAAGLYYLAELIEEYTVATSRIIKYMIWFSTAVLIGLYVFERFPTSMIGVGLFTNLVYFGLLQTFPFIMLTSPNFILSCGLVVVNHYLAFQFFAEEYYP----------------FSEVLAYFTFCLWIIPFAFFVSLSAGENVLPSTMQPGD----DVVSNYFTKGKRGKRLGILVVFSFIKEAILPSRQKIY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1R8-1", "uniprot_id": "Q9W1R8_DROME", "id": "Q9W1R8-1", "name": "Protein TEX261", "aln": "MAVLYLLGWVSLAIQIVFLTLSIVAGLYYLAELAEEYTTAARKCILFLISFTIFVYILLLLFEDLPWSLIICGLVAQGFHLGIMSGFPFVRLLSLPLLGSLAMLVVNHFLAFQHFVTVYVP----------------FTQVLAYFTICMWIVPFALFVSLSANDSVLPTTVSDQSRRSPDVVSNYFS---RNKKQGLLSLFQYLKEALLPGRTKKAF------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38869-1", "uniprot_id": "SVP26_YEAST", "id": "P38869-1", "name": "Protein SVP26", "aln": "-MLLELISYAGTVSGFLFLTLSIASGLYYISELVEEHTEPTRRFLTRAIYGIILILILLLLLDGFPFKLTLFSIACYIVYYQNLKSFPFISLTSPTFLLSCVCVVLNHYFWFKYFNDTEVPPQFKFDPNYIPRRRASFAEVASFFGICVWFIPFALFVSLSAGDYVLPTTSEQHMAKKNDDITTNNQPKFRKRAVGLARVVINSVRKYIYSLARVFGYEIEPDFDRLAV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ::.: . . *:**::.:****::** **:* .: : : * : * * ::: :* .: .: .: :. ***: * * :: * :*:**:: *:.* * *::* ::* :*:*::***:******.: ***:* . * ::. * : *: :. . : . : ", "identical_positions": 49, "similar_positions": 66, "identity": "21.4%" }, { "cls_id": "homologset.agr.SGD:S000001226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52209-1", "uniprot_id": "6PGD_HUMAN", "id": "P52209-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKG--------TKVVG--AQSLKEMVSKLKKPRRIILLVKAG-------------QAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGNKEAWPHIKT---------IFQGIAAKVGTGEPCCDW--------------VGDEGAGHFVKMVHNG----------IEYG-DMQLICEAY-HLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQ-------------------------DTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIG----------------------EAVFARCLSSLKDERIQASKKLKGPQK--FQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLN------YGGIALMWRGGCIIRSVFLGKIK-DAFDRNPE-------------------------------------------------------------------LQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG------------QFIHTNWTGHGGTVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCD0-1", "uniprot_id": "6PGD_MOUSE", "id": "Q9DCD0-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKG--------TKVVG--AQSLKDMVSKLKKPRRVILLVKAG-------------QAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGNKEAWPHIKA---------IFQAIAAKVGTGEPCCDW--------------VGDEGAGHFVKMVHNG----------IEYG-DMQLICEAY-HLMKDVLGMRHEEMAQAFEEWNKTELDSFLIEITANILKYR-------------------------DTDGKELLPKIRDSAGQKGTGKWTAISALEYGMPVTLIG----------------------EAVFARCLSSLKEERVQASQKLKGPKV--VQLEGSKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLN------YGGIALMWRGGCIIRSVFLGKIK-DAFERNPE-------------------------------------------------------------------LQNLLLDDFFKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLTKPG------------EFIHTNWTGHGGSVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q883-1", "uniprot_id": "F1Q883_DANRE", "id": "F1Q883-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKFSRDRITAVKTLIETLIFERNQTSTMAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKG--------TKVIG--AESLKDMVSKLKKPCRIILLVKAG-------------QAVDDFIDKLVPLLEPGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEDGAR-----------------------YGPSLMPGGHKDAWPHLKD---------IFQSIAAKVGTGEPCCDW--------------VGDEGAGHFVKMVHNG----------IEYG-DMQLICEAY-HLMKDVLCMNHDEMAQVFEQWNKTELDSFLIEITANILKFK-------------------------DADGTNLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIG----------------------EAVFARCLSSLKDERVQASKSLSGPQG--VKFTGNKAQFLEDIRKALYASKIISYAQGFMLLRQAALEFGWSLN------YGAIALMWRGGCIIRSVFLGKIK-EAFDRNPE-------------------------------------------------------------------LQSLLLDSFFSKAVQDCQDSWRRVVSTGVQQGIPMPSFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPG------------TFIHTNWTGHGGKVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41572-1", "uniprot_id": "6PGD_DROME", "id": "P41572-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGQADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKD--------TKVIG--ADSLEDMVSKLKSPRKVMLLVKAG-------------SAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGEEGAR-----------------------HGPSLMPGGHEAAWPLIQP---------IFQAICAKAD-GEPCCEW--------------VGDGGAGHFVKMVHNG----------IEYG-DMQLICEAY-HIMQS-LGLSADQMADEFGKWNSAELDSFLIEITRDILKYK-------------------------DGKG-YLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIG----------------------EAVFSRCLSALKDERVQASSVLKGPST--KAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLN------YGGIALMWRGGCIIRSVFLGNIK-DAYTSQPE-------------------------------------------------------------------LSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEG------------QFHHTNWTGTGGNVSASTYQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38720-1", "uniprot_id": "6PGD1_YEAST", "id": "P38720-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKG--------KSIIG--ATSIEDFISKLKRPRKVMLLVKAG-------------APVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGSEEAWPHIKN---------IFQSISAKSD-GEPCCEW--------------VGPAGAGHYVKMVHNG----------IEYG-DMQLICEAY-DIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFD-------------------------DVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIG----------------------EAVFARCLSALKNERIRASKVLPGPEVP-KDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLN------NPAIALMWRGGCIIRSVFLGQIT-KAYREEPD-------------------------------------------------------------------LENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECAS-----DNLPVDKDIHINWTGHGGNVSSSTYQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O88658-1", "uniprot_id": "KIF1B_RAT", "id": "O88658-1", "name": "Kinesin-like protein KIF1B", "aln": "MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDPCFASQSRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEDMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLMDDYSGSGGKYLKDFQNNKHRYLLASENQRPGNFSTASMGSLTSSPSSCSLNSQAGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERNNTGEVIVTLEPCERSETYVNGKRVAHPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKREKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPVPPELLPTEMGKTHEDRPFPRTVVAVEVQDLKNGATHYWSLDKLKQRLDLMREMYDRAGEVGSNAQDDSETTMTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDAMEDFDDEAFVDDTGSDAGTEEGSELFSDGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFPSAAMTRSGLSLEELRIVEGQGQSSEVISPPEEVNRMNDLDLKSGTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRHDEAFSTEPLKNNGRGSPLGFYHVQNIAVEVTESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPSRRFFPPPMPLSRPVPATKLNTMNKTSLGQSMSKYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKSLKSSHSSSRTFYRFEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRNLFGSGYSKSPDSNRVTGIYELSLCKMADTGSPGMQRRRRKVLDTSVAYVRGEENLAGWRPRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSMSDSLSPSLSSGTLSTSTSISSQISTTTFESAITPSESSGYDSADIESLVDREKELATKCLQLLTHTFNREFSQVHGSISDCKLSDISPIGRDPSVSSFSSSTLTPSSTCPSLVDSRSSSMDQKTPEANSRASSPCQEFEQFQIIPTVETPYLARAGKNEFLNLVPDIEEVRAGSVVSKKGYLHFKEPLSSNWAKHFVVVRRPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMLKTPNTFAVCTKHRGVLLQALNDKDMNDWLYAFNPLLAGTIRSKLSRRCPSQPKY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ** *: : : :..*. : . : :: * .:.:. ::* :.::: : :: :: : * . : : : . * *. .*. : :: : .: : : *: : * :* * : :: ::*. .: *:: : * * : : * ::* :: *.: . : : .:: . . .: :. . * : * : : .:** *.: .:: .**:* * .:.:: . .: ::. * .. : ..:.::* :: .*.: : : .* :: :.: *.. * . * :: ..: .*: * .: .* .. . :: . .:. ::*: *: . : : : :: . :.: . * . : ::: *.:* .. . ", "identical_positions": 47, "similar_positions": 174, "identity": "2.59%" }, { "cls_id": "homologset.agr.SGD:S000001229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDU2-1", "uniprot_id": "D3ZDU2_RAT", "id": "D3ZDU2-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEVLERLLPRTPPPPPPLMESEMLQSPLMGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEAHELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRSPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYTTGQEACLQGNLI-AICLEQLSDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPMVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYPLPSPA-ATEGGSLTPVRDSPCTPRLRSVSSYGNIRAVTTARNLNKSLQNLSLTEESGSSVAFSPGNLSTSSSASSTLGSPENEEYILSFETIDKMRRVSSYSALNSLIGVSFNSVYTQIWRVLLHLAADPYPDVSDLAMKVLNSIAYKATVNARPQRILDTSSLTQSAPASPTNKGMHIHQVG-------------GSPPASSTSS-CSLTNDVAKQTVSRDLPSSRPGTAGPTGAQYTPHSHQFPRTRKMFDKGPDQTTDDADDAAGHKSFICATMQTGFCDWSARYFAQP-------VMKIPEEH------DLESQIRKEREWRFLRNTRVRKQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDRETKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKAYLQKHPEGHIVSVSVNGDVRFFDPRMPES-VNVMQIVKG-----------LTALDIHPQANLIACGSMNQFTAIYNGNGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4Q0-1", "uniprot_id": "RPTOR_MOUSE", "id": "Q8K4Q0-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MESEMLQSPLMGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEAHELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRSPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYTTGQEACLQGNLI-AICLEQLSDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPMVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYPLPSPA-ATEGGSLTPVRDSPCTPRLRSVSSYGNIRAVTTARNLNKSLQNLSLTEESGSSVAFSPGNLSTSSSASSTLGSPENEEYILSFETIDKMRRVSSYSALNSLIGVSFNSVYTQIWRVLLHLAADPYPDVSDLAMKVLNSIAYKATVNARPQRILDTSSLTQSAPASPTNKGMHMHQVG-------------GSPPASSTSS-CSLTNDVAKQTVSRDLPSSRPGTAGPTGAQYTPHSHQFPRTRKMFDKGPDQTTDDADDAAGHKSFICASMQTGFCDWSARYFAQA-------VMKIPEEH------DLESQIRKEREWRFLRNTRVRKQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDRETKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKAYLQKHPEGHIVSVSVNGDVRFFDPRMPES-VNVMQIVKG-----------LTALDIHPQANLIACGSMNQFTAIYNGNGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N122-1", "uniprot_id": "RPTOR_HUMAN", "id": "Q8N122-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MESEMLQSPLLGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYHTGQEACLQGNLI-AICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLVSDGSPMVRKELVVALSHLVVQYESNFCTVALQFIEE--------EKNYALPSPA-TTEGGSLTPVRDSPCTPRLRSVSSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILSFETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYKATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAG-------------GSPPASSTSS-SSLTNDVAKQPVSRDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFCDWSARYFAQP-------VMKIPEEH------DLESQIRKEREWRFLRNSRVRRQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDREMKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPES-VNVLQIVKG-----------LTALDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IFI0-1", "uniprot_id": "A0A0R4IFI0_DANRE", "id": "A0A0R4IFI0-1", "name": "Regulatory-associated protein of mTOR", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MKMDAELLHSPVLGLAEEE----EVDMTDWNLPLAFMKKRHTEKIEGYKALAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTSPCARLECWIDPLSMS-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEIWVFNKNYTQYIPLSVYDLQTWMGSPSIFVYDCSNAGIIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACDASELLPMNPDLPADLFTSCLTTPIKIALRWFCMQKSAK---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLSMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPF-----------------------------------------------------------MPAEHRTMAVFILAVIVNNYNTGQEACLQGNLI-AICLEQLNDPHPLLRQWVAICLGRIWQNYDSARWCGVRDSAHEKLYSLLSDSIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPIVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYAVPSPANSTETGNITPSRDSPAIPRLRSVNSYTNLRAATTARTLNKSLQNLNLNEE-GGPAAFSPGNLSTSSSASSTLGSPDNDEYLLSFETIDKMRRVSSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPFPDVSDLAMKVLNSIAYKATMNARTQRILDSGSLTQSAPASPTSKGTLIHQAGASHRSKCSSSPSSGSPPMPGASS-SSLTNEVPKPPV-RDGPSARPPYT-PTLGGQAPHSQQFPRTRKMFDKGPDQTAEDGDETAVHRSFVSLSLQTGLCDWSAKYFAQP-------VMKIPEEH------DSESQVRKDREWRFLRNARVRKQSQRITQRGVT--RLDDQIFINRNPGVPSVVKFHPFNPCIAVAD-KDSICFWDWEKGERLDY-------------------------FYNGNPR------------------YTRITAMEYLNGHDCSLLLTATDDGALRIWKN--------FADQ-RNPEMVTAWQGLSDMLPTTRGLARRVS----------IYLDRSKQGGAGMVVDWEQETG-LLMTSGDVRVIRIWDTEREIKVQDIPTG-ADSCVTSLS---CDPQRSLVAAGLGDGSVRVYDRRMGPNECRVMTYREHG----AWVVKAHLQKEPEGHIISVSVNGDVRFFDPRMPES-VNTLQTVKG-----------LTALDIHPQANLFACGSMNQFIAVHNSNGDVISNIKYYDG-----------------FMGQRIGAISCLAFHPFWPHLAVG-SNDYYMSIYSAEKRLR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W437-1", "uniprot_id": "Q9W437_DROME", "id": "Q9W437-1", "name": "", "aln": "MTSAVRAKSAAAAVGVAVDESSGSSNGSVADQEVASSKEAVLSVLIRKRYEKYVFAPWDDPIILIMEQLEHIEHCRSAALGNQVAIGRDPSQDDSLNDLGKVISNMRQDQSLVPIVKHIEQISDIQASNGQELASLGSLRELIRTIRKEWPRDDSIKLRLKEIQILGMPPARSLCFGERIRDDRCPLSLQTKRHKERIQAMMYERQPWRIRERMKTASVALVLCLNIGVDPPDVVKIQPCSRLECWIDPSSVS-PPKAMELIGSNLQMQYERWQPRARYKKCNDPTVDDVKKLCTSLRRNAKGERILFHYNGHGVPKPTANGEIWVFNKTFTQYIPLSIFELITWMSAPSIYVYDCSNAGIIINSFQPYAKQHEEELGKALAAAQQRGGVQQLVGGSGGAANVAANQVQLTNQMVSYKNCIHLAACAANEILPMNAQLPADLFTSCLTTPINIALKWYAMQEKLG---------------MVPRIQSELIDKIP-----GKVNDRRTMMGELNWIFTAITDTIAWNTLPRELFQRLFRQDLLVASLFRNFLLAERILRSHDCTPVSLPALPP-CYRHPMWKAWDLVVDLALQQLPEILDHNAPYRQLP------------------------------------------------------------------------------FFEHQLTAFQVWLDSESESRTPPEQLPIVLQVLLSQVHRLRALELLARFLDLGPWAVNLALGVGIFPYVLKLLQSSTRELRPVLVFIWAKILAVDPS-CQVDLVKEY--KYFLSVLQDTS-----------------------------------------------------------VSKEHRTLSAFVLSSIVHNFLLGQTSALQGPLL-SICLEQLNDGSWLLRQWLAICLGMLWQNFEKARWSGARDLAHEKLYVLLRDSIPEVRAAAVFALGTFISSVTDRSEEQANNIDRIIAITMLETVGEDMSPLVRMELAAALQWMVVLFESQFVAVYLTEHMRGHV-----SAASFVMCPDPRDLTSSTHSLERHVTIRRGASSSSISNMGGASISSGTGSSSNPLGRSKS-GSGSSGGRGAAGAAGGTNSIPFQSIFTKLWLGICNLAQDPFPRVAAIAQEIVEHVRDTALCPIMAAKEATMANASEKCSSLSVSLPPSPNTRVNYLGGGGAPGGAGATAESPPVGAAASGASHWAQKLR---------LSGSGACMGAGDPQTILQRKLRTSSINDETDSGPGYSRGVAGAGT--GLGLPSGPRESTHSARSSGSESNHYLEPGHSLTPIVLTEFIPWAISYFTRPGKERYSSAEGSAEEGRQRFPVDRNSAELRRRRLRFLRNDFVRRHAGRKHQELIDPYGFDVCVWNRKTQFTPSIVKLLPYEPQIAVAY-REKVLVYDFQYNSVRTYGAESLGGNFTGYSSGYGSGSGSSSSLNGSTPRKSGAHTSGGGGGGFSAAPFARVSSIEFINAQDMALNLVAHEDGVVRVWQSSPPASSATSEDTPSKARLVTAWTALGQVNQHNHRQRSVASGGSIGKGADASGLSSAAIGSGGIVTAWQQCSQHLVIGGGGCRFIRIWDVERELKLADIPLGRSETCARVLSPYLPNMRSDVILAGCDDGSVRLFDKRCAPQDAGISVYRRHS----APILHASLRAN-GLVLVSGCTEGRISVADMRGSQSSINPFDVVYEWDAGGD-----VTAITSHQLEDTVACGNASK-IVIYSLDGRQQKVLRTNEG-----------------FIGPKIGHPTYLYFHPYKAQLAVG-FVDNTVAIYSPTPVL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38873-1", "uniprot_id": "KOG1_YEAST", "id": "P38873-1", "name": "Target of rapamycin complex 1 subunit KOG1", "aln": "------------------------------------------------------------------------------------------------------------------------------MPEIYGPQPLKPLNTVMRHGFEEQYQSDQLLQSLANDFIFYFDDKR--------HKTNGNPIPEEDKQRDVNRYYQPITDWKIMKDRQKTVSAALLLCLNLGVDPPDVMKTHPCARVEAWVDPLNFQDSKKAIEQIGKNLQAQYETLSLRTRYKQSLDPCVEDVKRFCNSLRRTSKEDRILFHYNGHGVPKPTKSGEIWVFNRGYTQYIPVSLYDLQTWLGAPCIFVYDCNSAENILINFQKFVQKRIKDDEEG---------------------NHDVAAPSPT---SAYQDCFQLASCTSDELLLMSPELPADLFSCCLTCPIEISIRIFLMQSPLKDSKYKIFFENSTSNQPFGDSKNSFKSKIPNVNIPGMLSDRRTPLGELNWIFTAITDTIAWTSLPRPLFKKLFRHDLMIAALFRNFLLAKRIMPWYNCHPVSDPELPDSITTHPMWKSWDLAMDEVLTKIVIDLKNAPPATALESQMILQQQETLQNGGSSKSNAQDTKAGSIQTQSRFAVANLSTMSLVNNPALQSRKSISLQSSQQQLQQQQQQQQQFTGFFEQNLTAFELWLKYASNVRHPPEQLPIVLQVLLSQVHRIRALVLLSRFLDLGPWAVYLSLSIGIFPYVLKLLQSPAPELKPILVFIWARIMSIDYKNTQSELIKEKGYMYFVTVLVPDWGVNGMSATNGSAMINSGNPLTMTASQNINGPSSRYYERQQGNRTSNLGHNNLPFYHSNDTTDEQKAMAVFVLASFVRNFPLGQKNCFSLELVNKLCFYIDNSEIPLLRQWCVILLGLLFADNPLNRFVCMNTGAVEILLKSLKDPVPEVRTASIFALKHFISGFQDAEVILRLQQEFEEQYQQLHSQLQHLQNQSHLQQQQSQQQQQHLEQQQMKIEKQIRHCQVMQNQLEVIDLRKLKRQEIGNLISILPLINDGSSLVRKELVVYFSHIVSRYSNFFIVVVFNDLLEEIKLLEKSDIN---TRNTSDKYSVSQGSIFYTVWKSLLILAEDPFLENKELSKQVIDYILLELSAHKELGGPFAVMEKFLLKRSSKAHQTGKFGFNSSQVQFVKSSLRSFSPNERVDNNAFKKEQQQHDPKIS-------------------HPMRTSLAKLFQSLGFSESNSDSDTQSSNTSMKSHTSKKGPSGLYLLNGNNNIYPTAETPRFRKHTEPLQLPLNSSFLDYSREYFQEP-------QMKKQEAD------EPGSVEYNARLWRRNRNETIIQETQGEKKLSIYG-NWSKKLISLNNKSQPKLMKFAQFEDQLITADDRSTITVFDWEKGKTLSK-------------------------FSNGTPFG------------------TKVTDLKLINEDDSALLLTGSSDGVIKIYRD---------YQDVDTFKIVSAWRGLTDMLLTPR--------------------------STGLLTEWLQIRG-SLLTTGDVKVIRVWDAHTETVEVDIPAK-TSSLITSLT--ADQLAGNIFVAGFADGSLRVYDRRLDPRDSMIRRWRAGNDKQGVWINNVHLQRGGYRELVSGATNGVVELWDIRSEDPVESFVDQNVTSQYGSQQKPTTMTCMQVHEHAPIIATG--TKQIKIWTTSGDLLNSFKNSHNNGVTSTLAATGIPKSLSYSSTSDAFLSSMAFHPHRMMIAATNSHDSIVNIYKCEDERIDYF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: : . . .:: : . : :::* **.*.**:****:*******:* **:*:*.*:** .. . **:* ** *** *** . *:***:. ** *::**::*.****.:* :*:**********:** .**:****: :*****:*:::* **:.:*.*:****..* *: .*: :. :: :: . * . : ::*::**:* : *:* * .:******:.*** **:*::: : **. . .: .*** * :.**** :****************. *** **::***:**::*:********:**: ::* *** * ** *.**::***.:* * :: :.. .. ** .:****::** : * ******************:*** **.********** *:*.:************.: **:*:******:*:::* . * :*:*: **::** . *:::::.*:*: :*..: ** .:. *: :*: .. ***** .* ** :: : *: . * * * * *.:**** *::*** *:.. : : * .. . : : : . :.:: . : . . * :: . : * . . :.. * . .: : : :.:: : . . . . : : : .. . : : : . : . . :. . : : : : : :: ** .. * : * . * * ** : :.: : : . : .. *.::*: : : .* :..: .:*:: .. : ...* :::: :: :* .* :* *.. .**.:::::. : . .:*:** .* :: : . *::. * * :: *. :.:*:**.. * *** :.: *: : .:. ** ***:*::*:* :. : :* . : :. *: ::* ..:* : . * * :. . .: :*.: * .* * .: : . .* . :: .. : . . : : ***. :*. * : :*. ", "identical_positions": 339, "similar_positions": 373, "identity": "18.47%" }, { "cls_id": "homologset.agr.SGD:S000001230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L85-1", "uniprot_id": "ELP5_MOUSE", "id": "Q99L85-1", "name": "Elongator complex protein 5", "aln": "------------------MLDSLLA---IGGLVLLRDSVEWEGRSLLKALIKKSALRGEQVHVLGCEVSEEEFREGFDSDVNS-RLVYHDLFRDPLNWS-KPGEAVPEGPLKALRSMCKRTDHG---SVTIALDSLSWLLCHIPCVTLCQALHALSQQNGDPGDNSLVEQVRVLGLLHEELHGPGSMG--ALNTLAHTEVTLSGKVD--QTSASILCRRPQQRATYQTWWFSVLPDFSLTLHEGLPLRSELHPDHHTTQVDPTAHLTFNLHLSKKEREARDSLTLPFQFSSEKQKALLHPVPSRTTGHIFYEPDAFDDVDPEDPDDDLDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IUP3-1", "uniprot_id": "ELP5_RAT", "id": "Q6IUP3-1", "name": "Elongator complex protein 5", "aln": "MPRLLSGDDIRRRPEASEMLDSLLA---TGGLVLLRDSVEWEGRGLLKALIKKSALRGEQVHVLGCEVSEEEFREGLGSDVNS-RLVYHDLFRDPLNWS-QPGEAAPEGPLKALRSMCRRTDRG---SVTIALDSLSWLLCHIPCVTLCQALHALSQRNVDPGDNPLIEQVRVLGLLHEELHGPGPVG--AVSSLAHTEVTLSGKMD--QTSASILCRRPQQRATYQTWWFSILPDFSLDLHEGLPLHSELHRDPHTTQVDPASHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLHPVPGQTTGRIFYEPDAFDDVDQEDPDDDLDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TE02-5", "uniprot_id": "ELP5_HUMAN", "id": "Q8TE02-5", "name": "Elongator complex protein 5", "aln": "------------------MLDSLLA---LGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHILGCEVSEEEFREGFDSDINN-RLVYHDFFRDPLNWS-KTEEAFPGGPLGALRAMCKRTDPV---PVTIALDSLSWLLLRLPCTTLCQVLHAVSHQDSCPGDSSSVGKVSVLGLLHEELHGPGPVG--ALSSLAQTEVTLGGTMG--QASAHILCRRPRQRPTDQTQWFSILPDFSLDLQEGPSVESQPYSDPHIPPVDPTTHLTFNLHLSKKEREARDSLILPFQFSSEKQQALLRPRPGQATSHIFYEPDAYDDLDQEDPDDDLDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5V9-1", "uniprot_id": "ELP5_DANRE", "id": "A1A5V9-1", "name": "Elongator complex protein 5", "aln": "-----------------MLLEVLQAAE-AGGFILIQDSVQCCGRGILRCCINAALKRDEDVHVLGFESPETEVCAGLDSSFAQ-KLHFHKGFPDPLGWRGKSSFTVQQFTSQHITQLIRDSQPAK--ASVLVVDSLSLVLRHHDPVIVCQSLQELRKGG--------VVKT-IIGLLHSDLHLQGIVG--IVCHLASTVISVAPTNNERHAVATTTRRTKSGKVMQEEEYFSVSEDATLSVQSKPRQHDRVEKEQDSAEVDPASNLTFNLRLSEEERRAKEKVALPFVFSQEKKSALLRPTPG--SGRIMYEPDANDDFDEEDPDDDLDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38874-1", "uniprot_id": "ELP5_YEAST", "id": "P38874-1", "name": "Elongator complex protein 5", "aln": "--------MASSSHNPVILLKRILSLTESSPFILCLDSIAQTSYKLIQEFVHQSKSKGNEYPIVYISFETVNKPSYCTQFIDATQMDFVHLVKQIISYLPAATATQAKKHMVIIDSLNYISTEYITRFLSEIASPHCTMVATYHKDIKDENRTVIPDWNNNYPDKLTLLQFMATTIVDIDVVLTGTLDTEEVSELLNEFRIPRGLNN--DIFQLRLVNKRKSGRSLEYDFIVNSNTHEYELLSTTKQEEESSSNGLETPEMLQGLTTFNLGTSNKQKLAKDQVALPFLEAQSFGQG----------GAIVYEYEKDDDYDEEDPYEDPF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : : . ::* **: . ::: :: : .:: :: . : . . :: : . . : :.: . : : : : .. . :: : : . . : : ::. :: * :. : * . . . : :: : . ... : . **** *:::: *::.: *** :.. .. . *.** : ** * *** :* ", "identical_positions": 25, "similar_positions": 87, "identity": "7.58%" }, { "cls_id": "homologset.agr.SGD:S000001231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIH3-1", "uniprot_id": "A0A8I6GIH3_RAT", "id": "A0A8I6GIH3-1", "name": "", "aln": "---MAAAMPLG--LSLLLLV--LVGQGCCGRVE--------------GPRD-------------------------------SLR-------EELVITPLPSGDVAATFQFRTRWDSDLQREG------VSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKP---LGLANDTDHYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAHCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLT----------EACPLASQSLVYVDITGYSQDNETLEVSPPPTSTYQDVILGTRKTYAVYDLFDTAMINNSRNLNIQLKWKRPP-------------DNEALPVPFLHAQRYVSGYGLQKGELSTLLYNSHPYRAFPVLLLDAVPWYLRLYVHTLTITSKGKDNKPIGQTPQILHTDGLVESLFPIETSQAISTICIALNILILQAPTEQLSYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVAAKPVDWEESPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPKSGG-----LAKRLANLIRRARGVPPL------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXQ2-1", "uniprot_id": "PIGT_MOUSE", "id": "Q8BXQ2-1", "name": "GPI-anchor transamidase component PIGT", "aln": "---MAAAMPLGLPLRLLVLL--LVGRGCCGCAE--------------GPRD-------------------------------SLR-------EELVITPLPSGDVAATFQFRTRWDSDLQREG------VSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWRELSNVLSGIFCASLNFIDATNTVTPTASFKP---LGLANDTDDYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAHCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLT----------EACPLASQSLVYVDITGYSQDNETLEVSPPPTSTYQDVILGTRKTYAVYDLFDTAMINNSRNLNIQLKWKRPP-------------DNEALPVPFLHAQRYVSGYGLQKGELSTLLYNSHPYRAFPVLLLDVVPWYLRLYVHTLTITSKGKENKP---------------------------------------------SYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSVVAAKPVDWEGSPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPKSGG-----LAKRLANLIRRARGVPPL------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969N2-1", "uniprot_id": "PIGT_HUMAN", "id": "Q969N2-1", "name": "GPI-anchor transamidase component PIGT", "aln": "---MAAAMPLA----LLVLL--LLGPGGWCLAE--------------PPRD-------------------------------SLR-------EELVITPLPSGDVAATFQFRTRWDSELQREG------VSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKP---LGLANDTDHYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLT----------EPCPLASESRVYVDITTYNQDNETLEVHPPPTTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPP-------------ENEAPPVPFLHAQRYVSGYGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKP---------------------------------------------SYIHYQPAQDRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPRTGG-----LAKRLANLIRRARGVPPL------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7V1-1", "uniprot_id": "A0ACD6B7V1_DANRE", "id": "A0ACD6B7V1-1", "name": "", "aln": "----MAAYRCGLYLALILILSRIVHPGIADTLEKANDTTGEKQSASDAPRDNADARSVDLNERQWQKTDVEPYTGDDPQNTPSVRPAKDQFEEELVIRPLHSGDIYASFQFRTLWDVDFQQEGQK----TSHYRLFPKSLGQVLSKFSVRELHISFTQGYWRTMQWGQP----FIASPPGAELWVWFHHT---VTDVDGNWRELTNVLSGIFCASLNFIDLTNTVQPSASFKP---LGLGNATDHSFLRYATLPREIVCTENLTPWKKLLPCGSKAGLAVLMKSEKLFHSSFHSQAVHIRPVCQDEQCTSKAWELRQTLNVVFDLYTSGQGKKEWSMFKMFSRTLT----------EACPLASSSKVYVDITD-NPEGELFELSPVTALLSQAVVLGDRRTYSVYDLTRAETFGQLRSLNLLLRWKG---------------ESGDMLRPLLHAERYVSGFGLQTGEIHTVIYNNHPFRAFPVLLMDSVPWYLQLYIHTLTVTSKSRENKP---------------------------------------------SYIHYQPAKDRHRPHLLEMLIQLPPHSMTEITVQFDRALLKWTEYTPDPNHGFYVGSSVVSALVPSMVAMNTNFTLDQPLFSSFVPVKEESSYFMRVYTEPLLVNLPTPDFSMPYNVICLTCTVVAVGYGSFYNLLTRTFQVDEP-SPP-----LAKRLANLIRRIRGVPLLT-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3G0-1", "uniprot_id": "Q9W3G0_DROME", "id": "Q9W3G0-1", "name": "", "aln": "MYPVAFVLLLLVAPNADANLG----------------------------RD-------------------------------DER-----FHEELVVRPLSGDHVNTYFQFTTRWHYGE-KDN------LYHTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYP----IVEATSGAEMWAWFSGANLTNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRP---QFMP-ANGQRFVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTANLVYDLRLFELSNNDFSLRRLFGMGLN----------GYCELAESSKIYVQRNE---LGERYQLVPEPVHEVKTTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLAPKSAN---------RRRNLAKPSLPPVTVHRYLLGHGQERGRIVTEVTNSH-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYG-------------------------------------GQRLTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLP-MGRNYTALPPEGHLFEHSFNATR-PSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVATKMIIVGRQTSAPKNF--VKKIFNQLFRRGKATDETAAEGEGLPAAGAAATGVASGRAAISPGSPSGDQPLLEDLDEEEEEEQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38875-1", "uniprot_id": "GPI16_YEAST", "id": "P38875-1", "name": "GPI transamidase component GPI16", "aln": "-----MILTLAYFMLGTLLLGVFAEDTVSQIGIN-----------------------------------------------DSLWYP---YDEALVLKPLPNNDLLLSFAFQLQSEPFDPAVSSMSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKEAGASGVELWSQVQAMD--QEQAFHNWKKLSNSLSGLFCSSLNFIDESRTTFPRRSYASDIGAPLFNSTEKLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISLDIATICSEDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLRCDTDKPFDSYQCFPLPEPSQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLSVDDTIFSTHDNCFDLSNDQNEGGSGYDFILESTDTTKVTPIVPVPIHVSRSLTGNGQDRGGMRIVFHNDN-DTPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQEN----------------------------------------DIILDKYYLQAADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVIT-----------------------VLSLESSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFGMLYNLMVKRMVTVEEADKITLQSGLKYKLLKLKEKFLGKKKTKTD---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * **: ** ...: * * . . * *: : ::.. : :::*: :*:* * ** ...*.*:* . :. .*::*:* :**::*:****:* :.: * . : . . :: * **.* :*******: **** . :*:: *:.. ::..: ::* .:.: :* : *: .:* . : : . * *.. * :.. . . . :. .: . ::: . : . * : * * : * : . * : .. :: : :**::: *: :* : . :* . :* * **: : :* :: :: :.: **:: **.**.***. :..:::: . .. . : *..*::.*.*********** *:.*::.: :* ::.: .: : . : : :* .: . ", "identical_positions": 96, "similar_positions": 172, "identity": "12.37%" }, { "cls_id": "homologset.agr.SGD:S000001232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86Y79-1", "uniprot_id": "PTH_HUMAN", "id": "Q86Y79-1", "name": "Peptidyl-tRNA hydrolase", "aln": "------MRPGGFLG--------AGQRLSRA--MSRCVLEPRPP----------GKRWMVAGLGNPG--LPGTRHSVGMAVLGQLARRLGVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVHDELDKPLGRLALKLGG-SARGHNGVRSCISCLNSNA-MPRLRVG-----IGRPAHPEAVQAHVLGCFSPAEQ-ELLPLLLDRATDLILDHIR-ERSQ-GPSLGP------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW00-1", "uniprot_id": "PTH_MOUSE", "id": "Q8BW00-1", "name": "Probable peptidyl-tRNA hydrolase", "aln": "------------------------MRRSWA--LSRQVSEARFP----------GKRWLVAGLGNHG--MPGTRHSVGMAVLGQIARRLGVAENWTRDSRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVARAAELFGLTAEEIYLVHDELDKPLGKLALKLGG-SARGHNGVRSCISCLNSNA-MPRLLVG-----IGRPTHPNMVENHVLGCFSPEEQ-ELLSPLMDQATDLLLDHIR-ARSQ-GPLSGL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8A9-1", "uniprot_id": "F1M8A9_RAT", "id": "F1M8A9-1", "name": "peptidyl-tRNA hydrolase", "aln": "MGAGVRMLKSGLFC--------PGMRRSWT--LSRQVSEARFP----------GKRWLVAGLGNPG--MPGTRHSVGMAVLGQIAQRLGVAENWARDSRCAADLALAPFGDAQLVLLRPRRLMNVNGRSVAKAAELFGLSAEEIYLVHDELDKPLGKLALKLGG-SARGHNGVRSCISCLNSNH-RLLLQVVHVVLVFTLLPSKLFLQRHVLLCELFFLQPELLQGTQLDSCPFGATRLV-SCPR-GP----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N4D8-1", "uniprot_id": "A0A8M1N4D8_DANRE", "id": "A0A8M1N4D8-1", "name": "peptidyl-tRNA hydrolase", "aln": "MSNTIVKSKAWAFVTQVFNLPMALLRRMITNLLNRVMMMSSLPPPKMDSQVDCKKRKMVVGLGNPG--MTGSRHSVGMAVLTTLAERLGAPDGWRSDRKVSGEVVVTQLQDVQLVLLRPKLLMNVNGVSVAKAASRYLIQPEHILLIHDELDKPLGKFGIKHGG-SARGHNGVRSCVDCLQTDV-MPRLRIG-----IGRPSDKTPIDRYVLGRFSKEEQ-NVLDSVIKQSLDVLLDYLTDSRSQTSPAEGRRAAQKKKARTLSPPQNSSEEQTQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38876-1", "uniprot_id": "PTH_YEAST", "id": "P38876-1", "name": "Peptidyl-tRNA hydrolase", "aln": "------------------------MSGKWR--------------------------LVLTGIGNPEPQYAGTRHNVGLYMLELLRKRLGLQGRTYSPVPNTGGKVHYIEDEHCTILRSDGQYMNLSGEQVCKVWARYAKYQARHVVIHDELSVACGKVQLRAPSTSIRGHNGLRSLLKCSGGRVPFAKLAIGIGREPGSRSRDPASVSRWVLGALTPQELQTLLTQSEPAAWRALTQYIS------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*:** .*:**.**: :* : .*** :. . : :* ** .* .*.:. : . ::****. . *:. :: . * *****:** :.* * : :. ** :* : : ", "identical_positions": 35, "similar_positions": 41, "identity": "12.68%" }, { "cls_id": "homologset.agr.SGD:S000001233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53798-1", "uniprot_id": "FDFT_MOUSE", "id": "P53798-1", "name": "Squalene synthase", "aln": "-----------------------MEFVKCLGHPEEFYNLLRFRMGGRRNFIPKMD------QDSLSSSLKTCYKYLNQTSRSFAAVIQALDGDIRHAICVFYLVLRALDTVEDDMSISVEKKIPLLCNFHTFLYDPEWRFT--ESKEKDRQVLEDFPTISLEFRNLAEKYQTVIDDICHRMGCGMAEFVDKD------VTSKQDWDKYCHYVAGLVGIGLSRLFSASEFEDPIVGEDIECANSMGLFLQKTNIIRDYLEDQQEGRKFWPQEVWGRYIKKLEDFAKPENVDVAVQCLNELITNTLQHIPDVLTYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGVVKIRKGQAVTLMMDATNMPAVKAIIYQYIEEIYHRIPNSDPSSSKTKQVISKIRT--QNLPNCQLISRSHY--SPIYLSF--------IMLLAALSWQYLSTLSQVTEDYVQR-EH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02769-1", "uniprot_id": "FDFT_RAT", "id": "Q02769-1", "name": "Squalene synthase", "aln": "-----------------------MEFVKCLGHPEEFYNLLRFRMGGRRNFIPKMD------RNSLSNSLKTCYKYLDQTSRSFAAVIQALDGDIRHAVCVFYLILRAMDTVEDDMAISVEKKIPLLRNFHTFLYEPEWRFT--ESKEKHRVVLEDFPTISLEFRNLAEKYQTVIADICHRMGCGMAEFLNKD------VTSKQDWDKYCHYVAGLVGIGLSRLFSASEFEDPIVGEDTECANSMGLFLQKTNIIRDYLEDQQEGRQFWPQEVWGKYVKKLEDFVKPENVDVAVKCLNELITNALQHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNHQVFKGVVKIRKGQAVTLMMDATNMPAVKAIIYQYIEEIYHRVPNSDPSASKAKQLISNIRT--QSLPNCQLISRSHY--SPIYLSF--------IMLLAALSWQYLSTLSQVTEDYVQR-EH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37268-1", "uniprot_id": "FDFT_HUMAN", "id": "P37268-1", "name": "Squalene synthase", "aln": "-----------------------MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMD------QDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFM--ESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKH------VTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT--QNLPNCQLISRSHY--SPIYLSF--------VMLLAALSWQYLTTLSQVTEDYVQTGEH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPK1-1", "uniprot_id": "A0A8M9PPK1_DANRE", "id": "A0A8M9PPK1-1", "name": "Squalene synthase", "aln": "MAGVCGKSAVSFSVLKRSLWLRSPRSVLCPGRSGALEARLAARAPHPLRALRHPANVCFSCQDSMSDTLRTCYAYLNQTSRSFAAVIQALDGELRHAVCIFYLVLRALDTVEDDMSIPLEQKLPLLQDFHTFLYQPEWSFS--QSREKDRRVLEDFPTISVEFRNLGQEYREVISDICHRMGVGMAEFLEKK------VSSMKEWDKYCHYVAGLVGIGLSRLFSASQLEEPEVGRDTELANSMGLFLQKTNIIRDYLEDQQQGRAFWPEEAWSQYASGLEDLAQPQHLSSALSCLNLLVTDALRHVPDVMLYLSRLRNQSVFNFCAIPQVMAIATLSACYNNPQVFQGVVKIRKGQAVTLMMQATNMSAVYSIITQYSHEILQKVSISDPSREKTLQILSVIRE--KSVHEGCVSSRAHHHISPVCVSA--------AMILAALSWQYLNTTAGPAGGADMQGH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29704-1", "uniprot_id": "ERG9_YEAST", "id": "P29704-1", "name": "Squalene synthase ERG9", "aln": "----------------------MGKLLQLALHPVEMKAALKLKFCRTP-LFSIYD-------QSTSPYLLHCFELLNLTSRSFAAVIRELHPELRNCVTLFYLILRALDTIEDDMSIEHDLKIDLLRHFHEKLLLTKWSFDGNAPDVKDRAVLTDFESILIEFHKLKPEYQEVIKEITEKMGNGMADYILDENYNLNGLQTVHDYDVYCHYVAGLVGDGLTRLIVIAKFANESLYSNEQLYESMGLFLQKTNIIRDYNEDLVDGRSFWPKEIWSQYAPQLKDFMKPENEQLGLDCINHLVLNALSHVIDVLTYLAGIHEQSTFQFCAIPQVMAIATLALVFNNREVLHGNVKIRKGTTCYLILKSRTLRGCVEIFDYYLRDIKSKLAVQDPNFLKLNIQISKIEQFMEEMYQDKLPPNVKPNETPIFLKVKERSRYDDELVPTQQEEEYKFNMVLSIILSVLLGFYYIYTLHRA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. : : : : :* * * *: *: *********: *. ::*:.: :***:***:**:****:* : *: ** .** * ..* * . *.* ** ** :* :**::* :*: ** :* .:** ***::: .. : : :::* ********** **:**: ::: : : : : :*************** ** ** ***:* *.:* * *: :*:: . .:.*:* *: ::* *: **: **: :::**.*:*************: :** :*::* ****** : *::.: .: . *: * .:* ::. .**. * :* *. :.: : : .. : :*: :. :: : . :* . ", "identical_positions": 145, "similar_positions": 123, "identity": "30.59%" }, { "cls_id": "homologset.agr.SGD:S000001235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQ95-1", "uniprot_id": "LNP_MOUSE", "id": "Q7TQ95-1", "name": "Endoplasmic reticulum junction formation protein lunapark", "aln": "MGGLFSRWRAKPST--------VEVLENIDKEIQALEEFREKNQRLQKLWVGRLIIYSSILYLFTCLIVYLWYLPDEFTARLVMTLPFFAFPLIIWTLRTVLIFFFSKRTERNNEALDDLKSQKKKILEEVMEKETYKTAKLILERFDPDSKKAKEFEPPSAGAAVTAKPGQEIRQRTAAQRNLSPAPASSSQGPPPQGPVSPGPAKDASAPGGPPERTVA----------PAL-----PRRLGSPA-TSVPGMGLHPPGPPLARPILPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAYCFFLNPARKTRPQAPRLPEFSFEKRQAVEGSSSTGPTLLESVPSAESQLIEDSLEEQDVLDNSTEQRDDKIPVTEQTSQVIEKTSGPEEPAENQEETENEETSTNEAKSPVLRADSVPNLEPSEESLVTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0JN29-1", "uniprot_id": "A0JN29_RAT", "id": "A0JN29-1", "name": "Endoplasmic reticulum junction formation protein lunapark", "aln": "MGGLFSRWRAKPST--------VEVLENIDKEIQALEEFREKNQRLQKLWVGRLIIYSSILYLFTCLIVYLWYLPDEFIARLVMTLPFFAFPLIIWTLRTVLIFFFSKRTERNNEALDDLKSQKKKILEEVMEKETYKTAKLILERFDPDSKKAKEFEPPSAGAAATAKPGQEIRQRTAAQRNLSPAPANSNQGPPPQVPVSPGPSKDASAPGGPPERTVA----------PAL-----PRRLGSPA-TSVPGMGLHPPGPPLARPVLPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAYCFFLNPARKTRPQAPRLPEFSFEKRQAVEGSSSTGPMLLESVPSPENQLTEDSLEEQDDLDNSTEQKDDKIPVTEQTNQVIEETSGPEGSEENQEETENEETSTNEAKSPVLRSDSVSNLELSEDSVVTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0E8-1", "uniprot_id": "LNP_HUMAN", "id": "Q9C0E8-1", "name": "Endoplasmic reticulum junction formation protein lunapark", "aln": "MGGLFSRWRTKPST--------VEVLESIDKEIQALEEFREKNQRLQKLWVGRLILYSSVLYLFTCLIVYLWYLPDEFTARLAMTLPFFAFPLIIWSIRTVIIFFFSKRTERNNEALDDLKSQRKKILEEVMEKETYKTAKLILERFDPDSKKAKECEPPSAGAAVTARPGQEIRQRTAAQRNLSPTPASPNQGPPPQVPVSPGPPKDSSAPGGPPERTVT----------PALSSNVLPRHLGSPA-TSVPGMGLHPPGPPLARPILPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAYCFFLNPARKTRPQAPRLPEFSFEKRQVVEGSSSVGPLPSGSVLSSDNQFNEESLEH-DVLDDNTEQTDDKIPATEQTNQVIEKASDSEEPEEKQE-TENEEASVIETNSTVPGADSIPDPELSGESLTAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFM4-1", "uniprot_id": "LNPB_DANRE", "id": "Q6PFM4-1", "name": "Endoplasmic reticulum junction formation protein lunapark-B", "aln": "MGAIISRWKTKPST--------VELLESLDKDIKDLEEFRAKNQRLLKLWVGRLLFYSSALYLLTCLCVYYLYFPQQWGARLITALPLLAFPALVLLLRKMLIFLFSKRTERNNDKLEDLKTQKRKILEEVMETETYKNAKLILERFDPESKKKAEAEATPVRPHMTPRPGQELRQRHIAMATPG-----PVLGP-----MSPGTTPLRTAPGGPPEKGLAGSASTPAGASQAETPQQMMRRSMNPY-SPGPGSGMRPPGPPLARPILPRERGAVDRVIEYLVGDGPQNRYALICQQCFSHNGMALKEEFEFVAFRCAYCYFMNPARKTRPQAPRLPEFSFERRLRSESPETQSSAATETPEDSDAPE--DDMERTTSADPQNPAADEAPVLQESETEESQPQDVPHAEAEALEEQKKEDESN--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZU80-1", "uniprot_id": "LNPA_DANRE", "id": "Q7ZU80-1", "name": "Endoplasmic reticulum junction formation protein lunapark-A", "aln": "MGAVVSRWRAKPST--------VEVLEGLDKDIQVLEEYREKNHKQLKLWVYRLLLYSALLYLMACAVVYAWYIPERMIGKLIVASPFLLFPLLIWLLRKLLIILYNKRTERNNEKLEELKAEKKKILEQVMETETYKNAKLILERFDPDSKKKLELETQPIGPTVTPRQGQELRHRLVSPRPTGRPPPVPVPGP-----SVPG-TPL-SAPGGPPEKGLS-----------ASTPQALIRRPGTPVGTPIPVMGMHPPGPPLARPVLPRERGAVDRVIEYLVGDGPQNRYALICQQCLSHNGMALKEEFEYIAFRCAYCYFLNPARKTRPQAPRLPEFAAEAKTSQDPP--AVAMETDLPVSPPAPESKEAGPEPVKAGDGDPQTDEIPTEEMKPGDPEPHTDIPDKSDGEQDVSAMEVE----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38878-1", "uniprot_id": "LNP_YEAST", "id": "P38878-1", "name": "Endoplasmic reticulum junction formation protein lunapark", "aln": "MFSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQSILSQWQSNLTFYGIALTVLALSYTYWEYHGYRPYLVVTALLCIGSLILFKWALTKLYAFYNNNRLR----KLAKLRAIHQKKLEKLKEETHYNATSSIIQRFSSGEDQ---------NDDAMVLLDDELNAKYQELNNLK--------------------TELEKFKKESHVKGLK-----------------------------------KEDSDAWFDKIISVLAGGNE--LDSTSSLSPFK--KIICPQCHWKS-NCYRLASKPIIFICPHCNHKIDEVKEREDAIEAKQPAQPSQSEKEKTK--------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ..:* . . . *. : .:*: *: *.: . * .* :*. * ::: .* * . : : : : : .: : .:* . * .*:: ::* **:: * *: :. *::**.. ..: .:*:. : . . . : : : . . ::. *. : :: . .* : :** ** :. . : : : * *.:* . * * :* . : : : : . ", "identical_positions": 36, "similar_positions": 92, "identity": "8.02%" }, { "cls_id": "homologset.agr.SGD:S000001236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9L0-1", "uniprot_id": "M0R9L0_RAT", "id": "M0R9L0-1", "name": "", "aln": "-MPGEATETVPATEQELPQPQAETAVLPMSSALNVTAAPGQPGS--PSPSSLGPQQSPLVTAAHQSS-PLPSSLPSTPFEVPFAQP---ETAVPSGAAPPAPTFLPHLIGPPISPAALALASPVIGPAQKGARSSSAPLSLVALAPHSIQKSSVCPPHPLTLPPSAAGAESGALTSLTASIPLLESKASTSQVPSQGTPNLKGTTTPCPPDVVSAFPSHLENPLASVQPGLTSCPQT-----LSITSP-VKGVPISSALT--QSLLSLNLRGPVSSPP---------------QSTVTPSIPPAASASLGSPLPLLHHSSLDSPVQPPGQSGLTVN-----TTISVDHPFVAASYPPERSAVSPLPSRHELAADSG-----AAPSIDKGSSAVTKETCSSSGSANEAG-TSLSPAAPLTPKSSNAALQPSVTQVPPPQKPGLKETPASCIRAMHPALDNPSTMSVAP------ATHVSPPASSGLIKSEDPASPVSSLSVPAAHKPFPAPSMSTTLGIPVSP-LPATEGLQNLPIS--VN--------------AGAPVSPAQAGLPIRKDTTVQTLAPVALKESPSSQSASS---LEVLSED--TKKTTGGPAPVVRPAIATGAPTT--LDYPPAGYVNPNPVSQPLKSSAPAMAPFLSESCDSKGLVPRTAKDTFPSVNSPLVPLPSEGCPVAP-SMALSHQNASVSVTT-------AKSVP-FPAPPSAGVSFSSAKKVDVVSQMESSDSSQEGHPNASVSSQTKRPASKKGSFPSDVSPGNVS------SPHCSLETSFLPEAGLSFQGPKGAS----------------------------IVPTETSVSSKKTPAEILPSPQKTPTATASRLTSAVQSPKLDPTVSDVIP-------ATVVPRDTSASLSLKSVPAVTSLSSQKAPAAPSPNEALVAPTEIPTSLKNALATTAPKETLATSTLKVASTAPVVTSPSPQKTPKSVSPKGAPAVTS-----KKAKEIAASKEVSTSQFPKEAPLLPHAAPTSPPKSPATDPLNGALTSPSPKVAPATLVESPTSPKKAPKTAAPKETPVTPSLEGVTAVPLEINPCPKKAPKTSTPKESSVTLSSKRTPKSAVSKEIPSNEVTAVPLEISLPLKETSKSAIPVEKSTSSSKSSPKTVAPKETLPEEVTAVP--LEVSLPPKEMPQNA------------------SPRETPPEGVTAVPLEIPPTPKKAPKTSVPKQIPVTPSPKDAFTTLAESPPSPKKAPTTAAPKEVPAAPSVGITAVS-EISPSPKKTSKTAVPKEDSATSYPKRSPKTATPKENSTSSPKRSPKIEAPKETLAT-SPEGVTAMPLEIPPSPAAPASKRVPVTPSPKGASNTLAESSASPKKAPKTAAPKETS-TPSPQKIPKMSGPKETPATPPSKKSPKTVAPKETSAPSEGVTALPLKVPPSPRKAPKTAVPKETPAPSPEGVTTALVQIPPSPRK-VKRTSSKETPTNPSPEGVTAAPLEIPLTSKKNPKMASPKEMLVTPPSKKVSQTGDPKETPPEGVTAVPLEILPSPKKTP--KTVVPKQVPVTPSPKDAPTTLAESPPSPKKAPTTAAPPSERVTTAPPEKPATPQKASATVASKVLVPAETLEVAVSPKET----------HPSSHKKTPKTVDLKEGPAALPPSPTKSPKISSSKKAQNTSAPIEFPASSSIKAVTTSLAQTVP-CVQKAPSTIAPQENSAAPVAIPVSNKSPAAPTTANASVALAAASLSPTPQVKISPSKKTPATSALQTVPKEATTIPSGKKAPAIETSNETSTTLSLKGAPKETSETSTSKGVLTSTVNSSSPKKVPSS---KRASTLPATTLPSIKEASVLSPVPTSSTKDSHTYPVSTACSTATTTPQASEKLPAKKEPAALTEVPAAP---APESALAITVPIQKVPRTKRNSA-SPPKCPDPSAKKDTKGLLSAVALAPQTVPVEKNSSKPIEVLPLCPAKGSDSVHSPKGPM---ESQEATPQAAFTSDKVLPKAVSKSVAPKPTLAASLTLAPSPVPPLPPKQPFLQSAPESVLESPSKLPVPADEDELPPLIPPEAVSGGVPFQPILVNMPTPKPAGIPAPAPSAKQPVLKNNKGSGTESDSD-ESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFK---VQGEA--VSNIQENTQTPTV-----------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H009-1", "uniprot_id": "NACA2_HUMAN", "id": "Q9H009-1", "name": "Nascent polypeptide-associated complex subunit alpha-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATET-----VPATEQELP---QSQAETG------------------------------------SGTASDSG-ESVPGIEEQDSTQTTTQKAWLVAAAEIDEEPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQAQLAAAEKFR---VQGEA--VGNIQENTQTPTV-----------QEESEEEEVDETGVEVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70670-1", "uniprot_id": "NACAM_MOUSE", "id": "P70670-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "-MPGEATETVPATEQELPQPQAETAVLPMSSALKV-AAVGQPGP--TPPSSLGPQQSPIVT-AHQPS-PLPSSVSSTPFEVPFAQPITAETALPSGTAPPTPTFLPHLIGPPISPAALALASPMIGLAQKGARSSSAPLSLVALAPHSVQKSSVCPPHPLTSPPSAAGAELGALT---ASIPPLEPKTSTSQVPSQGTLNLKG-TAPCPPDVVRAFPSHLENPLASVQPGLMSCPQT-----LSNTSP-VKGVPISSALT--QSRLSLNLKGPVSPPA---------------RNTAAPSIPLAPSTSLGCHLPLLHHSSVDSPIQPPGQSGLAVS-----NPTSVGHSGIAASCPPERCVVPALPSR-LLAVDSG-----AAPSDDKGSSAVTNELCSPPGSSNVAG-TSLSPKASLVPKGSNVALQPLVTQVPASQKTGLKEIPVSCIGATHHALDNPSAISVAP------ATHVPPPTSSGLVSSKDPASPVTSLVVPAAHKQFPAPPASATLGVPVSP-LPATEGLKNLPISALVN--------------VGAPVSPAQAGLPTRKDTTLQPLAPIALKESPSSQSASS---LEVLSEDTVTKKTTGGPAPVVRPAIAGVATTTSLRADSPPAVIRADSCVSPNTVSQP-----LKRSVTDPAMAPRTAKNTAPSTTSPLVPLASEGCPVAS-SMALSPQNASVSETALALSPEIPKSVP-FPDPPLAEISFSNARKVDAVSHMESSGSSRQGHPDASVTAKGTVVCLADSSLDTSVSASKGSALSGASSPLYPLEVSFLPEAGLAVQGPKGSLNKLSPTPPSSKGAPVPSTGAPPSPKGAPIVPTESSISSKQVPAEILPSPQKTPEVTASRLISAVQSPKVDPIMSDVTPTSPKKTSATAVPKDTSATLSLKSVPAVTSLSPPKAPVAPS-NEATIVPTEIPTSLKNALAAATPKETLATS-------IPKVTSPSPQKTPKSVSLKGAPAMTS-----KKATEIAASKDVSPSQFPKEVPLLPHVPPTSPPKSPVSDTLSGALTSPPPKGPPATLAETPTYPKKSPKPAASKKTPATPSPEGVTAVPLEIPPCSKKAPKTAAPKESSATSSSKRAPKTAVSKEIPSKGVTAVPLEISLPLKETSKSATPGEKSASSPKRSPKTAGPKETPPGGVTAVP--PEISLPPKETPQNATPNESLAASSQKRSPKTSVPKETPPGGVTAMPLEIPSAPQKAPKTAVPKQIPT---PEDAVTILAGSPLSPKKASKTAAPKEAPATPSVGVIAVSGEISPSPKKTSKTAAPKENSATLPPKRSPKTA-----------------APKETPAT-SSEGVTAVPSEISPSPPTPASKGVPVTLTPKGAPNALAESPASPKKVPKTAAPEETSTTPSPQKIPKVAGPKEASATPPSKKTPKTAVPKETSAPSEGVTAVPLEIPPSPRKAPKTAAPKETPAPSPEGATTAPVQIPPSPRKGSKKAGSKETPTTPSPEGVTAAPLEIPISSKKTSKMASPKETLVTPSSKKLSQTVGPKETSLEGATAVPLEIPPSHKKAP--KTVDPKQVPLTPSPKDAPTTLAESPSSPKKAPKTAAPPSERVTTVPPEKPATPQKASATTASKVPVPAETQEVAVSSRETPVTPAVPPVKNPSSHKKTSKTIELKEAPATLPPSPTKSPKIPSSKKAPRTSAPKEFPASPSIKPVTTSLAQTAPPSLQKAPSTTIPKENLAAPAVLPVSSKSPAAPAAASASLS--------------------PATAAPQTAPKEATTIPSCKKAAATETPIETSTAPSLEGAPKETSETSVSK-----VLMSSPPKKASSS---KRASTLPATTLPSLKEASVLSPTATSSGKDSHISPVSDACSTGTTTPQASEKLPSKKGPTAFTEMLAAP---APESALAITAPIQKSPGANSNSA-SSPKCPDPSSKKDTKGLPSAVALAPQTVPVEKDTSKAIETLLVSPAKGSDCLHSPKGPV---GSQVATPLAAFTSDKVPPEAVSASVAPKPAPAASLTLAPSPVAPLPPKQPLLESAPGSVLESPSKLPVPAEEDELPPLIPPEAVSGGEPFQPILVNMPAPKPAGTPAPAPSAKQPVLKNNKGSGTESDSD-ESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFK---VQGEA--VSNIQENTQTPTV-----------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZK3-1", "uniprot_id": "NACP4_HUMAN", "id": "Q9BZK3-1", "name": "Putative nascent polypeptide-associated complex subunit alpha-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATET-----VPAIEQQL---LQPQAETG------------------------------------SGTESDSD-ESVPELEEQDSTQ-VTAQVQLVVAAEIDEEPVSKAKQRRSEKKARKARFKLGLQQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYMVFGEAKIEDLSQEAQLAAAEKFK---VQGEA--VSNIQENTQTPTV-----------QEGSEDEEVDETGVEIKDIELVLSQANVWGAKAVRALKN-SNDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIU7-1", "uniprot_id": "NACA_DANRE", "id": "Q8JIU7-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATETVPVTEQEMQQPQAET--GSGTESDSD-ESVPDLEEGDSAQTQTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVAGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFK---VQGEA--VSNIQENTQTPTV-----------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNNNDIVNAIMELTM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PAV3-1", "uniprot_id": "NACAM_HUMAN", "id": "E9PAV3-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "-MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQS-SSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGS-VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATY---------HYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE-PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASS---MTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS-------------SPKECPTEDSGASATASSKGTL---------------------------------TYLADSPSPLGVSVSPQT--KRPPTKKGSAGPDTPIGNLSSPVSP-----VEASFLPENSLSFQGSKDSPATT-----HSPTPPSPKGAPTPSAVTPLSPKG--VTLPPKETPTPS---------VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT---------PSPKWAPTPPAATPPSPKGGP---------ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT------PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK----------------GGPATPSPKGAPMPPAATPPSPKGGLATPP---------HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA--------TPPSPKGGLATPPPKGAPTT--PAATPP-------------------SPKGGLATPSPKGAPTTPAATPPSP-----KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG---------SPGTPPPKGAPTPPAVTPPSPKGTPTLPAT-----TPSSKGGPTTPSSKEGPT------PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP---------ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS---------------APKGGPATPSSKGDPTLPAVTPPSPKEPP---APKQVATSSSPKKAPATPAPMGAPT-LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP--------------------PAMTVPS--PKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP---APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-LLPVQKDSSKT--------AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFK---VQGEA--VSNIQENTQTPTV-----------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94518-1", "uniprot_id": "NACA_DROME", "id": "Q94518-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELTEIKSEA-----APSTSAEAK----PEDVRVE----------------------------------DDGSDSDSD-GGMPGLEE--AVAATTQLGGGATGLPID--LVSKAKQSRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQVAAAEKFK---APEAAGAADSVGATTSVAPI-----------AEE-DEEDVDDTGVDEKDIELVITQANTTRAKAIKALKNNNNDIVNAIMELTML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5SWP3-1", "uniprot_id": "NACAD_MOUSE", "id": "Q5SWP3-1", "name": "NAC-alpha domain-containing protein 1", "aln": "MSALPLALRSAR-RAGARSLGLIGGRGSADVIYAPPPPSRGAVAVLATPSALTDRGTERQGYRQAHVQAMPGEAAGAELPLPEAGGPGSRTDHSCDAAIAT-----ILKGDQLEPHGLTPGPSPLALTFLSSKPGARPQ------------------------PEGASWDAGPSGAASAWVDPAEGSPSLVVLPEGLPLRPVPAEGPLPTTLEPRIVMGEETCQVIASP--------------RAAWPVLRDREGGHPALHPPPELCSQGDPPVPSPP---------------PDLESYFTPPSTPTKSTHALLPDHG------------------------PHRDAWDLEAELLDELLDSTPASPSGSYITADGD---------SWASSPSCSLSLLDPAEGLDFPSDWGLSPSGSVADDLE--------------PHPAAPPEPPSSESS---------------------LSADSSSSWSQEGHFFDPNFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEED----------------------VAATAAAAAPAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAAS-----------------SDSDSASYAGADDDRLYSGEPHAQP-----SAQNTEQAYR--------SRATFPG-IESTPQTSEQEICLTNSQE------------------------SVAEIAEEILTLGLESEAMRTPPDQQAAPGPQVEETPTVTPWVGNK--------------------------------------------------------------------------VDLVVEQVSKALPEPCQEGISTTLGCKPLTAEAIPDLQEGAS---------PSLCPVLPE-KKEEG-QGLPSTLEYVAVALEGPWKAEGGVTIPQDPLMTLPPLLQSTVPTS---------------------------------------------GPESVAVVALEPQQNEGCVTVLPDVPVVLP---------------------PSPQSVDPSSGPEAMAVATYEFQRAKEGTPGLQDSPVAASPALQGPDPTSEPEPEVVVTSRSQQDEGIVTVPQESPTASSLTLQSSHPTSDQER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAATLGPQQAEEGVTIP-----QVAPVASPSLLQGLESTSDLESVVVG-------------------TPESQQDEGIATATQDTPVMAP--------------PPLRGTDSTSDPE---------------LIAPDTSQALQREAGHTPGTKPSVSEAHQELGVASGP--------------RPVPKEGDAEPPPHSAPPASNQAQ-------------------------------------QNGSEPGYKSDSFGAPEE-SDSTLSTKTS---EPTSCMGEKVAANMSAPKQGACLEA----HDGVKTHSPQREALRSKNKRGRGTK---------------------------SPGQGNGPKSATSQGAVETCRAHSAARSEVSQPQLR---------SNEDTS-------------------GPRLPVAVSVQARLGSCPGSPARATCTLSRVYAEETS-RCAPPFQHLEPMLGLGSAEQPKVTPGILN----LSPDNSAGDLLTTSQNRFLDPDP---APSTLDRASQSSPGPPDPCLCPPPQKASEEEEKPPA--------SRGPMPRAGAQGAAAITTSGSTKPPGARQRVSLSPHST-LNPKVAPTDTKDLACIISSPCQVPPPSGTQNPSGPREFPALEQ----KDEDSLEEDAQRAPGSGQR--------WESHGESSSELDEYLAPPPDAQRTPGSGQRSESHGESSSELGEQD-LSPQKSQCPAQGPAGSNEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---VPSEP--SALVPELSPGPRVRPEC-----EEQEEEDEE-VEEAGLEPRDIELVMAQANVTRAKAVRALKDNHSDIVNAIMELTM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L8A8-1", "uniprot_id": "A0ABK0L8A8_RAT", "id": "A0ABK0L8A8-1", "name": "", "aln": "------MLRGRRGRAQPNGPRLSSGR---------EAMSRGAVAVLATPSALTDRGTERQGYRQAHVQAMPGEAAGAELPLPEAGGSGSRTDLPCDAAIAT-----ILKGDQREPHGLTPGPSPLALTFLSSKPGARPQ------------------------PEGASWDAGPSGAASTWVDPAEGSPSLVVLPEGLPLRPVPADVPLPTTLEPRIVMGEETCQVLPSP--------------RAAWPVLRDREGGHTALHPPPELCSQGDPPVPSPP---------------PDLDSYFTPPSTPTKTTYALLPDHG------------------------PHRGAWGLEAELLDELLDSTPASPSGSYITADGD---------SWASSPSCSLSLLAPAEGLDFPSEWGLSPSGSVVDELE--------------PHPTAPPEPPSSESS---------------------LSADCSSSWSQEGHFFDPNCLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEE-------------------------EGAAAAAAAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAAS-----------------SDSDSASYAGADDDRLYSGEPHAQP-----SAQNIEQEYR--------SRTAFPGAAEFTPQTSEQEICLTDSQE------------------------SAAEIAEEILTLGIESEATRTPPDRQTAPDPQVEEATTVTPWVENK--------------------------------------------------------------------------DDSVAEQASKALPEPCQKGTSMILGCKPLTAKAIPDLQEGAG---------PAMCPVLPENLKEGG-QGLPSTMEYVAVASVGPWKAEGGVAIPQDPFMTLPPLLQNTDPTS---------------------------------------------GPESVAVVMLEPQQDEGCVTVLQDVPVVSL---------------------PSPQSTDPTPGPEAGAMATFEFQQAKEGVPELQDTPVASSPALQASDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQ---------------DEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTVSSVPLQSSDPTSE-----------------------------------------------------------------------PEPEVAATLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDKEIVTVPQESPTASSVPLQSSDPTSEPEPEVAATPEPQQPEEGVTIP-----QVAPVALPSPLQGLDSTSDLESVVAG-------------------TMESWQDEGIATATQDMPVVAP--------------PPLGGIESTSDPE---------------LSAQDTPQALQREAGYTPGTKPSVSEAHQELGVALGP--------------RPVPKEQDAKPP-HSELPASDQAQ-------------------------------------QNGSEPVVKNDNLGVPGEGSGPTLSTKTS---EPLSCMGEKVTENLAAPKPGACLEA----HDGAKTHSPQRQASRAKNKCGRGPK---------------------------PPGQGKGSKSTASQGTTETFKAHSAARSETSQPQLMNSAGEGTSLSVKDSS-------------------GPRLPVAVSVQSKLGSCPGSPARATCTLSRVYSEETA-RCAPPFQHPEPVLGLGSGEQPKVTLGTLN----LSSENSAGDLLTTPQNRLLDPDPDPSAPSALNRAFQSSPGPPDPCLCPTSQKDPVEEEKPSA--------SHGLRSRAGVQGAAAITTSGSTKPLGARQRVSLSPHS--ANPKVTPTDAKDPACIISSPCQVPPPSGTQNPSGPRGFPAHEQ----EDEDSLEEDSQRAPGSGQ--------------------------------------HSESHGESSGELDEQD-ISPQKSQCPAQDPAGSNEETTAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---VPSES--SALVPELAPGPRVRPEC-----EEQEEEEEE-VEEAGLEPRDIELVMAQANVSRAKAVRALKDNHSDIVNAIMELTM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15069-1", "uniprot_id": "NACAD_HUMAN", "id": "O15069-1", "name": "NAC-alpha domain-containing protein 1", "aln": "---------------------------------------------------------------------MPGEAARAELLLPEADRPGPRTDLSCDAAAATT----ILGGDRREPCALTPGPSHLALTFLPSKPGARPQ------------------------PEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSP--------------RAARTALRDQEGGHASPDPPPELCSQGDLSVPSPP---------------PDPDSFFTPPSTPTKTTYALLPACG------------------------PHGDARDSEAELRDELLDSPPASPSGSYITADGD---------SWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERE--------------LHPAGTPEPPSSESS---------------------LSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEA--------------------------------VADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAAS-----------------SDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQE------------------------LISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETD-----------------------------------------------------------------------STAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETS---------LTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSS---------------------------------------------APKPVAAATIVSQQAEEGLTLPQDSVMTPP---------------------LPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG-----------------------------------------------------------------------------------------------LTLPQDSAMTPPLPLQDTDLSSA-----------------------------------------------------------------------PKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP-----QDSAMTPPLPLQDTDLSSAPKPVAAA-------------------TPVSQQAEEGLTLPQDSAMTAP--------------LPLQDTGPTSGPE---------------PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGP--------------RPAPEEKNAALPTVPEPAALDQVQ-------------------------------------QDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLK---------------------------PLAQEHGPRSALG-GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP-------------------EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDP--SAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPG--------SLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQ---EDEDSLEEDSPRALGSGQ--------------------------------------HSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---VPSEP--SALVPESAPRPRVRLEC-----KEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38879-1", "uniprot_id": "NACA_YEAST", "id": "P38879-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRS-AGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VPV7-1", "uniprot_id": "Q9VPV7_DROME", "id": "Q9VPV7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKKQKMKKAAQMATAAEKLKTAAEKSKTAADNVVAKEKPAEEASPSPSGSGKKGKPKATQKPNVAKALQKEISSSEDALDVKNKPPAGFSGAKGKPHIMG--------------------------------------------------------------------------------QMDPAYRNKIKKLMSLAKQLPPNVFSLPNSQKEEGASAAKSCVVEDDQSTDSDDAPDLVEAD--------------------------------------------------------PKETQPDEQGQLGTVAVRTREVSKQSRGERKARRILMKLDLKPMENVARVTMKKGKNILLYIDQPDVYRVAHSSTYIFFGEICVEDTSTTSVASQAAVKAAERFRGTSPAGRQGNEDGKAPGEESPHD----DDDDENDGEDADAMGLHAKDIELVQMQAACSRKKAIQALLKNDNDVVNAIMALTVG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*::**. **.* : .: *:*: * .* : * : :*:: .. *:.*** ::: : : : : .: .:. *::** *: :*::** .*:***** *: ", "identical_positions": 30, "similar_positions": 43, "identity": "1.27%" }, { "cls_id": "homologset.agr.SGD:S000001243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55036-1", "uniprot_id": "PSMD4_HUMAN", "id": "P55036-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLIT-LANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGP-SLADALISSPILAGE-GGAMLGLGAS---------DFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAG----------------IATTGTE---DSDDALLKMTISQ-QEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2A3N6-1", "uniprot_id": "PIPSL_HUMAN", "id": "A2A3N6-1", "name": "Putative PIP5K1A and PSMD4-like protein", "aln": "MASEVPYASGMPIKKIGHRSVDSSGGTTSSALKGAIQLGITHTVGSLSTKPESDVLMQDFHMVESIFFPSEGSNLTPAHHYNAFRFKTYAPVAFRYFWELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIVKTVRHKEAEFLQKLLPGYYINLNQNPRTLLPKFYGLYCVQTGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYRRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADVHNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALIHDGDTVSVHRPGFYAEWFQRFMCNTVFKKIPLKPSPSKKLRSGSSFSQRAGSSGNSCITYQPLVSGEHKAQVTTKAEVEPGVHLGCPDVLPQTPPLEEISEGSPTPDPSFSPLVEETLQMLTTSVDNSEYMGNGDFLPTRLQAQQDAVNTVCHSKTRSNPENNVGLIT-LDNDCEVLTTLTPDTGRILSKLHTVQPKGKITFCMGIHVAHLALKHRQGNNHKIRIIAFVGNPVEDNEKNLVKLAKCLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGP-SLADALISFPILAGE-GGAMMGLGAS---------DFEFGVDPSADPELALVLRVFMEEQRQRQEEEARQAAAASAAEAG----------------IATTGTE---DSDDALLKMTISQ-QEFGHTGLPDLSSMTEEEKIVCAMQMSLQGAEFGLAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAVGSLASQATKDSKKDKKEEDKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35226-1", "uniprot_id": "PSMD4_MOUSE", "id": "O35226-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLIT-LANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGP-SLADALISSPILAGE-GGAMLGLGAS---------DFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAG----------------IATPGTE---DSDDALLKMTINQ-QEFGRPGLPDLSSMTEEEQIAYAMQMSLQGTEFSQ-ESADMDASSAMDTSDPVKEEDDYDVMQDPEFLQSVLENLPGVDPNNAAIRSVMGALASQATKDGKNDKKEEEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55035-1", "uniprot_id": "PSMD4_DROME", "id": "P55035-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLESTMICFDNSDFQRNGDYFPTRLIVQRDGINLVCLTKLRSNPENNVGLMT-LSNTVEVLATLTSDAGRIFSKMHLVQPKGEINLLTGIRIAHLVLKHRQGKNHKMRIVVFVGSPINHEEGDLVKQAKRLKKEKVNVDIVSFGDHGNNNEILTAFINALNGKDGTGSHLVSVPRGS-VLSDALLSSPIIQGEDGMGGAGLGGN---------VFEFGVDPNEDPELALALRVSMEEQRQRQESEQRRANPDGAPPTGGDAGGGGGVSGSGPGNEESAGAENEANTEEAMLQRALALSTETPEDNLPDFANMTEEEQIAFAMQMSMQDAPDDSVTQQAKRPKTDEANAPMDVDEDYSEVIGDPAFLQSVLENLPGVDPQSEAVRDAVGSLN--KDKDKKSDGKDSQKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38886-1", "uniprot_id": "RPN10_YEAST", "id": "P38886-1", "name": "26S proteasome regulatory subunit RPN10", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANPRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEETSHLLTVTPGPRLLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDFGVDPSMDPELAMALRLSMEEEQQRQERLRQQQQ----------------------------------------------------QQDQPEQSEQPEQHQDK-----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: .***:: ***: **: .* *.:: : :* .*****.***:: .**:*:*.: *:*:: :* .* :*:: : .:::*:*.*****.: :: **:.** .*:.... :*:: ** ***::* ***:.**: *.* * *: ::*. : ***::*. *. * : : * **: * . . .:*.. ::*****. *****:.**: ***::**** :: . . *: :. .*:.: ", "identical_positions": 90, "similar_positions": 95, "identity": "10.07%" }, { "cls_id": "homologset.agr.SGD:S000001244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BIW1-1", "uniprot_id": "PRUN1_MOUSE", "id": "Q8BIW1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQDCRAALQ-----------------DSRPLHVVLGNEACDLDSMVSALALAFY--------LTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIPEPALIFRDEID--LLALHQAGQLTLILVDHHILPKSDAALEEAVAEVLDHRPIEQ------KYCPPCHVSVEL-VGSCATLVTERILQGAPETLDRQT--AALLHGTIILDCVNMDTNIGKATPKDSKYVEELEALFP-DLPKR-----KDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQG-----TKVAISAIYMDLKAFLQRTD----LFTDLSSFCHDHSYDALVAMTIFFNTQNEPVRQLAIFCP--HEALRMTICGILERSTSPPLKLTPIPSTSPNLQ--AYHQGNTQVSRKKLLPVLQEALSAYLDSAKMASGQSEVAVGMSREQVDKDLDKASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKFSAEAVFEKCSQISLSQSARACTSNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYG3-1", "uniprot_id": "PRUN1_RAT", "id": "Q6AYG3-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQDCRAALQ-----------------ESRPLHVVLGNEACDLDSMVSALALAFY--------LTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIAESALIFRDEID--LLALHQAGQLTLILVDHHMLPKSDAALEEAVAEVLDHRPIEQ------KYCPPCHVSVEL-VGSCATLVAERILQGAPETLDRQT--AALLHGTIILDCVNMDAKIGKATLKDNEYVEKLEALFP-DLPKR-----KDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQG-----TKVAVSAVYMDLEAFLQRSG----LLSDLSAFCQDHSYDALVAMAIFFNTHNEPVRQLAIFCP--HEALRMTICGVLEQSTSPALKLTPIPSISAHLQ--AYLQGNTQVSRKKLLPVLQEALSAYLDSMRTPAGQLEAALGMSREQADKELDKASNSLIAGLSQDDEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTRACPSNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TP1-1", "uniprot_id": "PRUN1_HUMAN", "id": "Q86TP1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQGCRAALQ-----------------ESRPLHVVLGNEACDLDSTVSALALAFY--------LAKTTEAEEVFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEID--LHALYQAGQLTLILVDHHILSKSDTALEEAVAEVLDHRPIEP------KHCPPCHVSVEL-VGSCATLVTERILQGAPEILDRQT--AALLHGTIILDCVNMDLKIGKATPKDSKYVEKLEALFP-DLPKR-----NDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQG-----VKVAISAIYMDLEAFLQRSN----LLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCP--HVALQTTICEVLERSHSPPLKLTPASSTHPNLH--AYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETAD-VSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18399-1", "uniprot_id": "O18399_DROME", "id": "O18399-1", "name": "", "aln": "-----MCFLRFLAQARGTLGRHLAEASPVAWAAAPDVSGRKLHLVMGNESCDLDSAVSAVTLAFV--------YAQR-HREHDYVPILNIPRRDYPLKTEVGHLFVKCGIAEPVLLFRDDIP--REVVQDVN---VILVDHHVSP-----LAPNVTEILDHRPLEDSSPSFKQLPTLCQLDIDASVGSCATLVAQRYLAED-QPRSTSV--AQLLHATIVLDTINFAPAAKRYGPKDEAMVQKLESELNRKDAQR-----SSLFDELVAARADISKLTLTEVLRKDMKVLQTDR-----QVVPLAGMPILVRDFVEKSG----AEKAVREFGVESNLLVILGMYVSP-ADGQVQRDLALISLSGQGQFVQRVQQALMESNDPKLELRPHEVDTRFMGGCFLRQHNVQATRKHILPIVKRALLEWEADHACDCD-----------------------------------------------------------EVYFFKEKPQLGLS----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38698-1", "uniprot_id": "PPX1_YEAST", "id": "P38698-1", "name": "Polyphosphatase", "aln": "MSPLRKTVPEFLAHLKSLPIS-------------KIASNDVLTICVGNESADMDSIASAITYSYCQYIYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFFIEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQ-------KHLDAEPRIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTSNMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDIKGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGGEADFVNQCRRFQAERGLDVLVLLTSWR-KAGDSHRELVILGD-------SNVVRELIERVSDKLQLQLFGGN-LDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :. .. * : :***:.*:** .**:: :: :: . :*:::* * : .*: : ..: : * * *:* ::: : : ***:: . *. ::**: .. : ***::** : . * ** .:*::* *: . : : : . . : ..::..: : *:. :: ::*:** * . : : ::.: : :.:. . * . .:: : .: *:*.:: : * . . *:* * *.:.:**:::* ::.* ", "identical_positions": 52, "similar_positions": 116, "identity": "10.08%" }, { "cls_id": "homologset.agr.SGD:S000001246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62702-1", "uniprot_id": "RS4X_MOUSE", "id": "P62702-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62701-1", "uniprot_id": "RS4X_HUMAN", "id": "P62701-1", "name": "Small ribosomal subunit protein eS4, X isoform", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62703-1", "uniprot_id": "RS4X_RAT", "id": "P62703-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22090-1", "uniprot_id": "RS4Y1_HUMAN", "id": "P22090-1", "name": "Small ribosomal subunit protein eS4, Y isoform 1", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQRFIKIDGKVRVDVTYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITVEEAKYKLCKVRKITVGVKGIPHLVTHDARTIRYPDPVIKVNDTVQIDLGTGKIINFIKFDTGNLCMVIGGANLGRVGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGNGNKPWISLPRGKGIRLTVAEERDKRLATKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TD47-1", "uniprot_id": "RS4Y2_HUMAN", "id": "Q8TD47-1", "name": "Small ribosomal subunit protein eS4, Y isoform 2", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQHFLKIDGKVRVDITYPAGFIDVISIEKTGEHFRLVYNTKGCFAVHRITVEEAKYKLCKVRKITVGTKGIPHLVTHDARTIRYPDPLIKVNDTVQIDLGTGKITSFIKFDTGNVCMVIAGANLGRVGVITNRERHPGSCDVVHVKDANGNSFATRISNIFVIGNGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H9-1", "uniprot_id": "RS4X_DANRE", "id": "Q642H9-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPTGFMDVVSIEKTGENFRLIYDVKGRFTVHRITNEEAKYKLCKVRKILIGTKGIPHLVTHDARTIRYPDPLIKVNDTIRIDLDTGKITDFIKFETGNMCMVTGGANLGRIGVITNREKHPGSFDVVHVKDSIGNSFATRLSNIFVIGKGNKPWVSLPRGKGVRLTIAEERDKRLAAKQSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41042-1", "uniprot_id": "RS4_DROME", "id": "P41042-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIVMQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQLGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAKTH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX36-1", "uniprot_id": "RS4B_YEAST", "id": "P0CX36-1", "name": "Small ribosomal subunit protein eS4B", "aln": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:***: *:**** * :*****:*******.***::**********.* **. * **: :*:*****.* ***:*::**:::: *.* ***:*:.** *.:***: ***.*** **:* :* **:*.:****.******** *:.**::::*: :*** .:***::*:: : .* ****:*.:.::*:* *. *:**:**: .: *.**:.*:*:**: .**::***:***::*::*****:* * : ", "identical_positions": 149, "similar_positions": 80, "identity": "56.65%" }, { "cls_id": "homologset.agr.SGD:S000001247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925U4-1", "uniprot_id": "EDEM1_MOUSE", "id": "Q925U4-1", "name": "ER degradation-enhancing alpha-mannosidase-like protein 1", "aln": "MQWRALVLGLVLLRLGLHAVLWLVFGLGPSMGFYQRFPLSFGFQRLRDPDG-----SGPVGPPG---GPAWLHRPRRGTEGRLETPPEPGPTPGPGVCGPAHWGYALGGGGCGPDEYERRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIYCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVS---FDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIEDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVP-----PDSNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQSYLRRGREACNEGEGDPPLYVNVNMFSGQLMN-TWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQ------------------LQAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSKEDRMESFFLSETCKYLYLLFDEENPVHKSGTRYMFTTEGHIISVDKRLRELP----------------------------------------------------------------------------------------------------WKEFFSEDGERDQEEKFVHRPKSQELRVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJE0-1", "uniprot_id": "D3ZJE0_RAT", "id": "D3ZJE0-1", "name": "alpha-1,2-Mannosidase", "aln": "MQWRALVLGLVLLRLGLHAVLWLVFGLGPSMGFYQRFPLSFGFQRLRDPDG-----SGPVGPPG---GPSWLHRPRRGTEGRLETPPGPG--PGPGVCGPAHWGYALGGGGCGLDEYERRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIYCRGRGPDLGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVS---FDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIEDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVP-----PDSNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQSYLRRGREACNEGEGDPPLYVNVNMFSGQLMN-TWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQ------------------LQAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSKEDRMESFFLSETCKYLYLLFDEENPVHKSGTRYMFTTEGHIISVDKRLRELP----------------------------------------------------------------------------------------------------WKEFFSEDGERDQEEKFVHRPKSQELRVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92611-1", "uniprot_id": "EDEM1_HUMAN", "id": "Q92611-1", "name": "ER degradation-enhancing alpha-mannosidase-like protein 1", "aln": "MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPG---TGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVS---FDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVP-----PDTNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMN-TWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQ------------------LQAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELP----------------------------------------------------------------------------------------------------WKEFFSEEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEF7-1", "uniprot_id": "A0A8M2BEF7_DANRE", "id": "A0A8M2BEF7-1", "name": "alpha-1,2-Mannosidase", "aln": "------MWMLHSATMLP--AFWLLFFMGTCIRLS----------------------------------------------------------------------------------------ETMSRDEKSKLRIQVLEMFDHAYRNYMDHAYPADELMPLTCRGRVRG-LEPSRGDVDDALGKFSLTLIDTLDTLALLNKTVEFEEAVRRVVKDVR---LDNDIVVSVFETNIRVLGGLLGGHSMAVMLKE--NGQ-MVWYQNELLHMAKDLGLRLLPAFN-TSSGLPYPRVNLRHGVHGPETRTGTETETCTACAGTIILEFAALSRFTGDPTFEAHARRALDFLWEKRQRNSNLVGTTINIHSGEWVRRDSGVGAGIDSYYEYLMKAYILLGDDQLLLRFNTHYASIMKYIS-----------QPPLLLDVHIHKPLLPARTWMDSLLAFFPGLQVLKGDIRPAIETHEMLYQVTKKHNFLPEAFTTD------------------FRV-HWAQHPLRPEFAESTYFLYKATRDPYYLEVGRTVLENLNRFARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLFLLFAEEEDLPFNVEDYVFTTEAHLLPLSLSTASNSPAPPVINSVVIEELDDLNFEWTCPNTRLLFPDPAFPRNFREPIRSAVDKSCLRPIAHREPGMGRPPLRAQDFMANNPEHLELLRRMGVSLIHLKD---GRVQLVQHATQAVSAVAAEDGMRFMQEMMELSSQQQKEQLPP-RAVQIVSHPFFG-RVVLTAGPAQFGMDLSKSSSGVRGFVTVAEPYNGCSE-LSNGEIVAGRIALLQRGQCMFAEKARHVQKAGAIGGIVIDDNEGSSSDTAPLFQMAGDGRNTDDVTLPLLFLFHKEGNILLEALKEYKEVEVLLSDKARDREAIFKGKALPGALLDGTTDGAEEEDCSTEERDHSSPAPSEPVDQSQVTTQEQTAGDSESVQPAEGLGSYVSVDAGEEPPADEDSNNQSVDSLMADWQEDLEAFKQMEKDEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK27-1", "uniprot_id": "Q9VK27_DROME", "id": "Q9VK27-1", "name": "alpha-1,2-Mannosidase", "aln": "------MSTTSSESFVRGQRLMLIFLVAMCIVVACVLSTETTMP-----------------------------------------------------------------------------TQNMSNKERAELREEARDMFYHAYNAYMQNAYPADELMPLSCKGRYRG-VTPSRGDMDDILGNFSMTLVDTLDTLVLLGDFTEFDHAVKLVIRDVQ---FDSDIIVSVFETNIRMVGGLLSAHILAEYLQK--HADTMHWYKGELLEMSRELGYRLLPAFN-TSTGIPHARVNLRLGMKDPMLKK--SRETCTACAGTILLEFAALSRLTGDPIFEVRAHAAMDALWKLRHRGSDLMGTVLNVHSGDWVRRDSGVGAGIDSYYEYLFKSYVLLGDDKYLARFNRHYNAVMKYVS-----------EGPMLLDVLMHRPHAKSKNFMDSLLAFWPGLQVLSGDLKPAVQTHEMLYQVMQMHTFIPEAFTVD------------------FQI-HWGQHPLRPEFIESTYFLYRATGDHHYLQVGKKALKTLQQHAKVSCGYAAVNDVRTGKHEDRMDSFVLSETIKYLFLLFSDPQDLIINVDEFVFTTEAHLLPLSIAQLGN----ATFSFRQTDEHNVLDFMRTCPSSNRLFP-----EKVRKPLRNFITGSCPRTTAGKR-------LSALDFQASNADHLRAVYDMGITMVSVGDRSQGKVRLFHSFYNAKSHEEGEMGLQFMQEMLELTKMQSINQLAQLQAVAYATDENSQDWIALMAGPSHFSPELTG-DQFVEGDVILAKPLRACDESLENAEEAKGKVLVAERGDCTFVSKARLAQKVGAAALIVCDNVPGSSGETQPMFAMSGDGK--DDVLIPVVFMYSMEFGKLSAVMQRRKQPLRVR----VMQMVEFKRWQLA-----------------KEQR------------------QNQTASVAQ--KPEKEL---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38888-1", "uniprot_id": "MNL1_YEAST", "id": "P38888-1", "name": "ER degradation-enhancing alpha-mannosidase-like protein 1", "aln": "--------MVCCLWVLLALLLHLDHVACEDDAYS------------------------------------------------------------------------------------------FTSKELKAYKQEVKELFYFGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNFTITLIDSLTTIAILEDRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHLYATDPTK--AVYLGDDYDGSLLRLAQNMADRLLPAYL-TSTGLPMPRRNIKRKWDVSEFPEFLETENNVAAMASPMFEFTILSYLTGDPKYEKVTRYAFDKTWSLRTG-LDLLPMSFHPEKLTPYTPMTGIGASIDSLFEYALKGAILFDDSELMEVWNVAYEALKTNCKN------------DWFFANVMADTGHLFVPWIDSLSAFFSGLQVLAGDLDDAIANHLMFLKMWNTFGGIPERWNFSPPEFPPLSPLERSGAVALDNILPLEWYPLRPEFFESTYFLYRATKDPFYLNIGVHLLKDLKQRFKSNCGFAGFQNVITGELQDRMETFVLSETLKYLYLLFDEENELHNSASDVIFSTEAHPMWLPQEVRSNY---------------------------------------------------------------------------------------------------KRNAKFNNSVYSSHLEICQKKDREQAGENTLSQRIVGFAKSIFHKGPPDEEATDPIIDYTIDTELPGTCSIKPHHVIGDEFWYSPMLSNFDRLFEIDSRFAATLIKPSHMHNYNAIELEPGFYNRWSNPQFSTCLIPPTTEIFELLFDLPGYHQLNPLMLENKTITFETFGGRSRLKIEKLQIYQIDYYGDLITASTFQDVSRKDIFSNACDAVASLYSPTYLYRVVAINGRILPRHGSVQIKKHSPVLTSNGTREEDEFKMDGIGINDHSQLMLECTPIINLFIV-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . :. . : . :* ..: *: :.:* **: *: * : . *: . :* **::::**:*:* *:.:: . :* .**: * . . :* * :.*** .**::*.**..* : *...** :::::. *****: *.:*:* .* *:: . *. .* .: :.** ** : **. :* :: *.. *. * .*: .: .. :*:**.:** :** :*. :*:.:.: : :* * :: . . : ::*** **:.***** **: *: * : : : . :** :. . . :*****: ****:**:** : .**.:* *: *:: : **:* .:.* . :***::*.*:* ***:*** : : : . :*:**.* : : . . : . . : . ", "identical_positions": 123, "similar_positions": 160, "identity": "11.96%" }, { "cls_id": "homologset.agr.SGD:S000001248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4U9-1", "uniprot_id": "SGK2_RAT", "id": "Q8R4U9-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPVG-------------------------VPSPQPSRANGNINLGPSAN------------------------------PNARP-------TDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVR--HPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHS-LNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEP-YDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPG-GRTVAACDLLQGLLHKDQRQRLGS-KEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKS---------IGCTPD---TMSSSSGASS-----------AFLGFSYAQDDDDILDS-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS5-1", "uniprot_id": "SGK2_MOUSE", "id": "Q9QZS5-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPVG-------------------------VPSPQPSRANGNINLGPSAN------------------------------PNARP-------TDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVR--HPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHS-LNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEP-YDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPG-GRTVAACDLLQGLLHKDQRQRLGS-KEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKS---------IGCTPD---TVASSSGASS-----------AFLGFSYAQDDDDILDS-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVC6-1", "uniprot_id": "SGK1_MOUSE", "id": "Q9WVC6-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVKAEAARST--LTYSRMRGMVAILIA------------------------------------------FMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEP---------------------ELMNANPSPPPSPSQQINLGPSSN------------------------------PHAKP-------SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK--HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKP-NITNSARHLLEGLLQKDRTKRLGA-KDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSS---------IGRSPDSILVTASVKEAAE-----------AFLGFSYAPPVDSFL---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06226-1", "uniprot_id": "SGK1_RAT", "id": "Q06226-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVKTEAARST--LTYSRMRGMVAILIA------------------------------------------FMKQRRMGLNDFIQKLANNSYACKHPEVQSYLKISQPQEP---------------------ELMNANPSPPPSPSQQINLGPSSN------------------------------PHAKP-------SDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK--HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK--NITNSARHLLEGLLQKDRTKRLGA-KDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSS---------IGRSPDSILVTASVKEAAE-----------AFLGFSYAPPMDSFL---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZTW4-1", "uniprot_id": "SGK1_DANRE", "id": "Q7ZTW4-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTIQTETSVSAPDLTYSKTRGLVANLSA------------------------------------------FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTPPQDV---------------------ELMNSNPSPPPSPSQQINLGPSSN------------------------------PTAKP-------SDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK--HPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKP-NISNAARHLLEGLLQKDRTKRLGF-TDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNS---------IGCSPDSALVTSSITEATE-----------AFLGFSYAPAMDSYL---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ERE3-1", "uniprot_id": "SGK3_MOUSE", "id": "Q9ERE3-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRDCIMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQS----------------DPSEDEDERSTSKPHSTSRNINLGPTGN------------------------------PHAKP-------TDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVK--HPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHS-IKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQP-YDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRP-GVSLTAWSILEELLEKNRQNRLGA-KEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYS---------VCVSSDYSIVNASVLEADD-----------AFVGFSYAPPSEDLFL--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4V0-1", "uniprot_id": "SGK3_RAT", "id": "Q8R4V0-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRDCTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQS----------------DPSEDEDERSTPKPHSTSRNINLGPTGN------------------------------PHAKP-------SDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVK--HPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHS-IKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQP-YDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRP-GVSLTAWSILEELLEKNRQNRLGA-KEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYS---------VCVSSDYSIVNASVLEADD-----------AFVGFSYAPPSEDLFL--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AQL0-1", "uniprot_id": "A0A8M3AQL0_DANRE", "id": "A0A8M3AQL0-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKKAKSPVTYAKMKGIVSYFTA------------------------------------------LIKDKKL----------RSSHPIYHHFYHSRMDFLRPEGS----------------------LSDDDRATAVCYSNPVREEPQSQ------------------------------VSAG---------DFDYLKVIGTGSFGKVFLATHRENGKYYAVKVLQKHIILTRKEERNVMCEHRVLLKTLN--HPFLVKLHFSFQTKERLYLVLDYACGGELFYHLQREGVFGEARARFYAAEMACALGYLHS-LKIVYRDLKPENILLDSAGHVVLTDFGLCKEGMSGRGTTRTFCGTPEYLAPEVLLQEE-YDRTVDWWGLGAVLHEMLYGLPPFYNADRLEMLRNIIYQPLALKA-GVSSAARDLLKRLLNRDRAKRLGA-KRDLIELQSHAFFSPIQWDELVAKKIQPPYVPVLSGPGDLTNIDPRFTELPVPHS---------LGACEDHGANFPGFTFINE-----------NILSLTRGH---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63484-1", "uniprot_id": "AKT3_RAT", "id": "Q63484-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDVTIVKEDWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQ---------------RQE--EERMNCSPTSQIDNIGEEEMDASTT------------------------------HHK-----RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTES-RVLKNTR--HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITIT---------PPEKDDDDGMDCMDNERRP-----------HFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA6-1", "uniprot_id": "AKT3_MOUSE", "id": "Q9WUA6-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQ---------------RQE--EERMNCSPTSQIDNIGEEEMDASTT------------------------------HHK-----RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTES-RVLKNTR--HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITIT---------PPEKYDDDGMDGMDNERRP-----------HFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y243-1", "uniprot_id": "AKT3_HUMAN", "id": "Q9Y243-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQ---------------RQE--EERMNCSPTSQIDNIGEEEMDASTT------------------------------HHK-----RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTES-RVLKNTR--HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITIT---------PPEKYDEDGMDCMDNERRP-----------HFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT6-1", "uniprot_id": "E7EXT6_DANRE", "id": "E7EXT6-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDLNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--ADLA-YPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEERDEWVEAIQMVADKLA---------------KQE--EEGILCSPISQIENVNEEEMDTSTS------------------------------HHK-----RKTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTES-RVLKNTR--HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-AKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIKFPR-TLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTALDWQDVYDKKLVPPFMPQVSSETDTRYFDEEFTAQTITIT---------PPEKYDEDGMDAADSERRP-----------HFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q60823-1", "uniprot_id": "AKT2_MOUSE", "id": "Q60823-1", "name": "RAC-beta serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA--PDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLK---------------QRGPGEDAMDYKCGSPSDSSTSEMMEVAVN------------------------------KARA----KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES-RVLQNTR--HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITIT---------PPDRYD--SLDPLELDQRT-----------HFPQFSYSASIRE-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31751-1", "uniprot_id": "AKT2_HUMAN", "id": "P31751-1", "name": "RAC-beta serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA--PDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLK---------------QRAPGEDPMDYKCGSPSDSSTTEEMEVAVS------------------------------KARA----KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES-RVLQNTR--HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITIT---------PPDRYD--SLGLLELDQRT-----------HFPQFSYSASIRE-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31750-1", "uniprot_id": "AKT1_MOUSE", "id": "P31750-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VDQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLK---------------RQE--EETMDFRSGSPSDNSGAEEMEVSLA------------------------------KPKH----RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN-RVLQNSR--HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITIT---------PPDQDD--SMECVDSERRP-----------HFPQFSYSASGTA-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47196-1", "uniprot_id": "AKT1_RAT", "id": "P47196-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VEQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLK---------------RQE--EETMDFRSGSPSDNSGAEEMEVALA------------------------------KPKH----RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN-RVLQNSR--HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITIT---------PPDQDD--SMECVDSERRP-----------HFPQFSYSASGTA-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31749-1", "uniprot_id": "AKT1_HUMAN", "id": "P31749-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLK---------------KQE--EEEMDFRSGSPSDNSGAEEMEVSLA------------------------------KPKH----RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN-RVLQNSR--HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITIT---------PPDQDD--SMECVDSERRP-----------HFPQFSYSASGTA-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INB9-1", "uniprot_id": "AKT1_DROME", "id": "Q8INB9-1", "name": "RAC serine/threonine-protein kinase", "aln": "------------------------------------------------------------------------------------------------------------MNYLPFVLQRRSTVVASAPAPGSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQTQVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVG--------EVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGT------------------------------TCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTES-RVLKSTN--HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS-QGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDND-YGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPR-NITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELT---------PPDPTG----PLGSIAEEP-----------LFPQFSYQGDMASTLGTSSHISTSTSLASMQ-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11792-1", "uniprot_id": "SCH9_YEAST", "id": "P11792-1", "name": "Serine/threonine-protein kinase SCH9", "aln": "MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPCKLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHD-NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVDESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNMNNSHSQMDFDGDQHMDDEFVSGRFEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *:::*.*.:*:* .: **:*:* *. :: ..* : : * :: . **: *:::*** * :* :: *****:**.:* * * *::** **: *: :**. ::***:* **::** *:: : ****.* : *****.******:: .: * . **:* *.::.** * **: : : * : : . :: ** :: :*** * :: * ** : * : *:: **: * : . * :* ** : : ", "identical_positions": 93, "similar_positions": 83, "identity": "11.23%" }, { "cls_id": "homologset.agr.SGD:S000001249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5ND04-1", "uniprot_id": "HSF5_MOUSE", "id": "Q5ND04-1", "name": "Heat shock factor protein 5", "aln": "MEEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGAGGAGGAGSSGGGGGSGVGAAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFRRDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNR-------FQRLLITSASASASASTSPLQHQDPPPQPAGPRPEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSAFPLKGLDRTP-IPPRTWQNSLGMHPGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPPTHMDALSSCVTPTASSYAHCNYFQNPPMQSSYPVEFLPSNWPCSATDENKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVETQCPSSQANRGQHILPNANSSNPSSTSQASQLEPLTPVGSDITSFVVGTEQAITCSLPQSPEYIYTIH-TAQPLENSTMQESATIQQTHVKLKEQLNHNPSPSSVVFVQEGLPFSTPQVDSSIKCQTNPSENILPSEQMGFLISEMGPANKSTKDTGLSTPARYRERRSNSQGKSPDLHLLVDVACKQEHFPKEEELKE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G7F5-1", "uniprot_id": "A0A8I6G7F5_RAT", "id": "A0A8I6G7F5-1", "name": "Heat shock factor protein 5", "aln": "MEEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGAGGAGGAGSSGGGGGSGVGAAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFRRDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNR-------FQRLLITSASASASASTSPLQHQDPPPQPAGPRPEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSTFPLKGLDRTP-IPPRTWQNSLGMHPGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPSTHMDALSSCVTPTASSYAHCNYFQNPPMQSSYPVEFLPSNWPCSATDDSKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPSSQSNRGQHILPNSNSSNPSSTSQASQLEPLTPVGSDITSFVVGTEQAITCSLPQSPEYIYTIH-TAQPLENSTMQESATMQQTHVKLKEQLSHNSPPSSVVLVQEGLPFSTPQVDSSIKCQTNPPESILPSEQMGFLISEMGPASKSSKDTGLSTPARYRERRSNSQGKSPDLHLLVDVACKQEHFPKEEELKE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96LI6-1", "uniprot_id": "HSFY1_HUMAN", "id": "Q96LI6-1", "name": "Heat shock transcription factor, Y-linked", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVSSET-------QDVSPKDELTASEASTRSPLCEH-TFPGDS----DLRSMIEEHAFQVLSQGSLLESPSYTVCVSEPDKDDDFLSLN----FPRKLWK----IVESDQFKSISWDENGTCIVINEELFKKEILETKAPYR-IFQTDAIKSFVRQLNLYG----FSKIQQNFQRSAFLATFLSEEK----------ESSVLSKLKFYYNPNFKRGYPQLLVRVKRRIGVKNASPISTL----FNEDFNKKHFRAG-ANMENHNSALAAEASEES----LFSASKNLNMPLTRESSVRQIIANSSVPIRSGFPPPSPSTSVGPSEQ----------IATDQHAILNQLTTIHMHSHSTYMQARGHIVNFITTTTSQYH-IISPLQNGYFGLTVEP--SAVPTRYPLVSVNEAPYRNMLPAGNPWLQMPTIADR-----SAAPHSRLALQPSPLDKYHPNYN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIQ7-1", "uniprot_id": "Q5XIQ7_RAT", "id": "Q5XIQ7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAPSDM-------LDVSPNSLSTDSETSSGDPWCDNNTGQKDS----ELWAIIEESAFQVLAQRFLIKRPPHTLCASEPDEDSNLFSMT----FPRKLWK----IVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFR-IFETDSMKSLVRQLNLYG----FRKMRQNFQRSASLPDFLAEEK----------GISASCKLQFYQNPNFLRDCPHLIERMKRRIGIKTVSRGAAP----SLPDFKNKHFRPDLGKMDDHSLGVAVQTSERN----LLSGSSISNVYLRQKPSLTQGSSDSMDVIRSDFS-LATSSSFRPPEE----------VLTHRPAPLNDVSSLHMDSQRIYTQANDSTVNFIITSITQNRRDMSHLWNSCIEMQGEP--SFQPG-FPHFSSSSSTYSDSKAKGEP--ELPIHKER-----VAS--TTLASTSN----HHPSS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1B0GWH4-1", "uniprot_id": "HSFX3_HUMAN", "id": "A0A1B0GWH4-1", "name": "Heat shock transcription factor, X-linked member 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MASQNTEQ-------EYEAKLAPSVGGEPTSGGPSGSSPDPNPDSSE--VLDRHEDQAMSQDPGSQDNSPPEDRNQRVVNVEDNHNLFRLS----FPRKLWT----IVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAER-IFKTDSLTSFIRQLNLYG----FCKTRPSNSP-------------------------GNKKMMIYCNSNFQRDKPRLLENIQRKDALRNTAQQATR-----VPTPKRKNLVATRRSLRIYHINARKEAIKMC-----QQGAPSVQGPSGTQSFRRSGMWSKKSATRHPLGNGPPQEPNGPSWEG-----------TSGNVTFTSSATTWMEGTGILSSLVYSDNGSVMSLYNICYYALLASLS---------------------VMSPNEPSDDEEE------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1B0GTS1-1", "uniprot_id": "HSFX4_HUMAN", "id": "A0A1B0GTS1-1", "name": "Heat shock transcription factor, X-linked member 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MASQNTEQ-------EYEAKLAPSVGGEPTSGGPSGSSPDPNPDSSE--VLDRHEDQAMSQDPGSQDNSPPEDRNQRVVNVEDNHNLFRLS----FPRKLWT----IVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAER-IFKTDNLTSFIRQLNLYG----FCKTRPSNSP-------------------------GNKKMMIYCNSNFQRDKPRLLENIQRKDALRNTAQQATR-----VPTPKRKNLVATRRSLRIYHINARKEAIKMC-----QQGAPSVQGPSGTQSFRRSGMWSKKSATRHPLGNGPPQEPNGPSWEG-----------TSGNVTFTSSATTWMEGTGILSSLVYSDNGSVMSLYNICYYALLASLS---------------------VMSPNEPSDDEEE------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UBD0-1", "uniprot_id": "HSFX1_HUMAN", "id": "Q9UBD0-1", "name": "Heat shock transcription factor, X-linked", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MEDKRSLSMARCEERNSRGQDHG-------LERVPFPPQLQSETYLHPADPSPAWDDPGSTGSPNLRLLTEEIAFQPLAEEASFRRP-HPDGDVPPQGEDNLLSLP----FPQKLWR----LVSSNQFSSIWWDDSGACRVINQKLFEKEILKRDVAHK-VFATTSIKSFFRQLNLYG----FRKRRQCTFRTFTRIFSAKR------------LVSILNKLEFYCHPYFQRDSPHLLVRMKRRVGVKSAPRHQEE----DKPEAAGSCLAPADTEQQDHTSPNENDQVTPQHR---EPAGPNTQIRSGSAPPATPVMVPDSAVASDNSPVTQPAGEWSEGSQAH---------VTPVAAVPGPAALPFLYVPGSPTQMNSYGPVVALPTASRSTLAMDTTGLPAPGMLP------FCHLWVPVTLVAAGAAQPAASMVMFPHLPALHHHCPHSHRTSQYMPASDGPQAYPDYADQST-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38889-1", "uniprot_id": "SKN7_YEAST", "id": "P38889-1", "name": "Transcription factor SKN7", "aln": "MSFSTINSNVNKTTGDSNNNTTENSSTADLLGMDLLQSGPRLMNTMQPNNSSDMLHINNKTNNVQQPAGNTNISSANAGAKAPANEFVRKLFRILENNEYPDIVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFVRQLNKYDFHKVKRSPEERQRCKYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKALLHFNSEGTNPNNPSGSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVELQKLNSKYNTVIESLITFKTINENLLNNFNTLCSTLANNGIEVPIFGDNGNRNPTGNTNPATTTAIQSNNNTNNASPATSTVSLQLPN---------LPDQNSLTPNAQNNTVTLRKGFHVLLVEDDAVSIQLCSKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLDG----ATATSIVRSFDNETPIIAMTGNIMNQDLITYLQHGMNDILAKPFTRDDLHSILI-RYLKDRIPLCEQQLPPRNSSPQTHSNTNTANSNPNTINEQSLAMLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQHQIFHAQQQQQHHNAIANARSDVAIPNLEHEINTVPHSSMGSTPQLPQSTLQENQLS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5CZP2-1", "uniprot_id": "HSF4_DANRE", "id": "Q5CZP2-1", "name": "Heat shock factor protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MQENPGSIG---------VDGGYASNVPAFLTKLWTLVEDPETNHLICWSATGTSFHVFDQGRFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVNIEQSGLVKP--ERDDTEFQHLYFLQGHEHLLEHIKRKVSIVKSEETKVR----QEDLSKLLYEVQVLRSQQENMEMQMQDMKQQNDVLWREVVS----------LRQNHTQQQKVMNKLIQFLFSQMQSNSPSTVGMKRKLPLMLDDGCSTPPASKFSHNHSMESLQESFYIQSPSTESASCSTSSVMTGGPIISDVTEIPQSSSMALQMQAEESREKCLMLIKEEPVSPGVQGRAEGVPLGSCEVCAEPPVLPVAMVQSVLEGRGSNLGERRAKRPMLERPEIPDGVENVDMSLEDLQLLLRSHQQSMENNAAAMDQFTFSLPLNEWNFAEMDPNLKSELANALIPAAVSQYMFQGQEGELYPTAGYEEQ----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : : : . . . ", "identical_positions": 0, "similar_positions": 11, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000001250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GMV2-1", "uniprot_id": "SMYD5_HUMAN", "id": "Q6GMV2-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVAGRARVSVEVRFVSSAKGKGLFATQLIRKGETIFVERPLVAAQF-----LWNALYRYRACDHCLRALEK--AEENAQRLTGKPGQVLP--HPELCTVRKDLHQNCPHCQVMYCSAE--CRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKG----QLELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIG-TSSLSQWVHACD-TLELKPQDREQLDAFIDQL----------------------YKDIEAATGEF-----LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADEPN------------------VTSEEEEEEEEEEEGEPEDAELGDEMTDV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZII8-1", "uniprot_id": "D3ZII8_RAT", "id": "D3ZII8-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVAGGARGSVEVRFVSSAKGKGLFATQLIRKGETIFIERPLVASQF-----LWNALYRYRACDHCLRALEK--AEENAQRLTGKPGQVLP--HPELCSVRKDLHQNCPRCQVTYCSAE--CRLAAAEQYHQILCPGPSQDDPRHPLNKLQEAWRSVHYPPETASIMLMARMVATVKQAKDKDHWVRLFSHFCSKTANEEEEIVHKLLGDKFKG----QLELLRRLFTEALYEETLSQWFTPDGFRSLFALVGTNGQGIG-TSSLSQWVHACD-ALELKPQEREQLDTFIDQL----------------------YKDIEAATGEF-----LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIEPGEEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADDPN------------------VTSEEEEEEDEEE-GEPEDAELGDEMTDV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYX3-1", "uniprot_id": "SMYD5_MOUSE", "id": "Q3TYX3-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVADRARGSVEVRYVDSIKGKGLFATQLIRKGETIFIERPLVAAQF-----LWNALYQYRACDHCLRALEK--AEENAQRLTGKPSQILP--HPELCSVRKDLHQNCPHCQVMYCSAE--CRLAAAEQYHQILCPGPS-HDPRHPLNKLQEAWRSVHYPPETASIMLMARMVATVKQAKDKDHWVRLFNHFCSRTANQEQAIVHKLLKGKFKD----QLELLLGLFKEALYEEALSLWFTPEGFRSLFALVGTNGQGIG-TSSLSQWVHACD-ALELTPQDREQLDTFIDQL----------------------YKDIEAATGEF-----LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFVLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLFNCSCPKCLAEADDPN------------------VTSEEEEEEDEEE-GEPEDAELGDEMTDV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RET2-1", "uniprot_id": "SMYD5_DANRE", "id": "F1RET2-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAAPVDDMFSRCVDSA-KASNCVDVRFINNVKGKGLFAKKPFKKGDTIFIERPLVSSQF-----LWNALYKYRACEYCLRALET--AEENARRLSGLPALILP--HPELCKVRPDRHQACPQCQVMYCSSE--CRQAAMDQYHKILCLGPSNDDPDHPVNKLQDAWRSVHFPPETSSVMILAKMVATIKQTQDKERWQRLFTNFCSRTANEEEEIVHKLLGEKFQG----QLGLLRNLFTTALYEDRLSQWFTPEGFRSLFSLVGTNGQGIG-TSSLSQWVHACD-ALELPRQQREQLDAFIDQL----------------------YKDIDKETGDF-----LNCEGSGLFLLQSSCNHSCVPNAEASFPENNFLLHLTALGDIGPGEEICISYLDCCQRDRSRHSRHKILRENYLFICSCQKCLSQMDDAD------------------MTSEDEEEVEGEG--ETEGEDMEDEMTDV------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDD0-1", "uniprot_id": "Q9VDD0_DROME", "id": "Q9VDD0-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "--------------------------------------MNNFEIRELP-GKGRAMIATKNFAKDEVIFEEEPFVSRQF-----SWNVAYGYAACDHCMRPLET--VLENVRRLASDPKVEVPLLQHDPTAQWVAQFTQCPRCKVRYCSED--CLMEAQKRYHRVACMGAFHSDDTHPINVLNETWKKMHYPPETGSIMLIVRLMALYQQSTKKEEFLEQLQSFQSLIVNREQKIYHKMLGENFEQ----QMEQLYLAFCNAFTGEEFSIFKTPDAFKTLMAILGTNSQGIA-TSVLSQWVAKVS-DLPLTDSEKEQLDTVIDGL----------------------YAKVGEFAGEF-----LNNEGSGLYLLQSKINHSCVPNACSTFPYSNDIVVLKALAPIQQGEEICISYLDECMLERSRHSRHKVLRENYVFICQCPKCRAQASDPD------------------ETSEDDDDDDEMD-----DYDDDDDMN--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38890-1", "uniprot_id": "SET5_YEAST", "id": "P38890-1", "name": "Histone-lysine N-methyltransferase SET5", "aln": "MTLTIKIGTLNDSDQSAVHNGTENGSDFRKITPTEEEICDDVVLLWKEEPGTEDATIQHLYDRITERNQSWKLSASRFRK---ILNEHHLYDTDLETVSLYKD--KIHFPKALDSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKP--IVYIPPLDKLFLISNGKACARCGKALYDLTQHKIMVHYLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRFVNYCEKYCFTAAFSVGLIYGSMLLDTTGEVKEQWQKLASISQRERIKLRDASGIGSTFSLLNGTTVHT-EEESDNGTKKGVEKNIDDETVWEKCYELFCGAFPKASEEIDFEKFLTMIGTFN----INQYNGQVYHWISFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQIRITYVNPLHGVR---LRRRELRVNWGFLCQCDRCQNELSTFERVPNLEKKNADANLGVEKIDSNDSSEDGSKKSTGNRKSSMREAQPDLKEILKNGKEFELDIPETVDTQGNVRKTSVRFDSNVSVAVDER", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D4A3D2-1", "uniprot_id": "D4A3D2_RAT", "id": "D4A3D2-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "----MTVGSMENVEVFTS-EGKGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQERLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGK--VPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRQQLKKQYYFDCSCEHCQKGLKDDLFLAVKEDPKP-SQEVVKEMTQFSKDTLEKIDKAR--------------SEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIVSEVLSYLQAFEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPS-----------------HPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M6Z3-1", "uniprot_id": "SMYD2_RAT", "id": "Q7M6Z3-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-----MRAEARGGLERFCSAGKGRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLECSSMVVFGENWNPSETVRLTARILAKQKMHPERTPSEKLLAVREFESHLDKLDNEKKDLIQSDIAALHQFYSKHLEFPDHSSLVVLFAQVNCNGFTIEDEE-LSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGDEVFTS-------------YIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDKAKVEIRKLSNPPQAEAIRDMVRYARNVIEEFRRAKHYK--------------SPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGRLYMGLENKAAGEKALKKAIAIMEIAHGKDHP----------------YISEIKQEIESH-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : * . . : . :. . . . : . :: .. . :: . .. . :: . ", "identical_positions": 1, "similar_positions": 30, "identity": "0.18%" }, { "cls_id": "homologset.agr.SGD:S000001251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54687-1", "uniprot_id": "BCAT1_HUMAN", "id": "P54687-1", "name": "Branched-chain-amino-acid aminotransferase, cytosolic", "aln": "-----------------------------------------MKDCSNGCSAECTGE-------------GGSKEVVGTFKAKDLIVTPAT--ILKEKPDPNN-LVFGTVFTDHMLTVEWSSEF-GWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINED-GEEELATPPLDGIILPGVTRRCILDLAHQWG---EFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTM--ENGPKLASRILSKLTDIQYGREES-DWTIVLS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24288-1", "uniprot_id": "BCAT1_MOUSE", "id": "P24288-1", "name": "Branched-chain-amino-acid aminotransferase, cytosolic", "aln": "-----------------------------------------MKDCSNGCSAPFAGE-------------RGSEEVAETFRAKDLIITPAT--VLKEKPDPDS-LVFGATFTDHMLTVEWSSAS-GWEKPHIKPFGNLPIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMDRMCRSAVRTTLPMFDKEELLKCILQLLQIDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPSKALLFVILSPVGPYFSSGSFTPVSLWANPKYIRAWKGGTGDCKMGGNYGASLLAQCEAVENGCQQVLWLYGKDNQITEVGTMNLFLYWINED-GEEELATPPLDGIILPGVTRQSILELAQQWG---EFKVCERHLTMDDLATALEGNRVKEMFGSGTACVVCPVSDILYKGQMLHIPTM--ENGPKLASRILGKLTDIQYGRVES-DWTIELP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54690-1", "uniprot_id": "BCAT1_RAT", "id": "P54690-1", "name": "Branched-chain-amino-acid aminotransferase, cytosolic", "aln": "-----------------------------MAYLSRATATLARQDCSNGCSASYAEEEELEASTESYDEEGGSEASTQTFRAKDLIITKAD--VLKKKPDPSS-LVFGASFTDHMLMVEWTSKY-GWDKPHIKPFENLSIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMKRMCRSAVRTTLPEFDKEELLQCVLQLIQLDREWVPYSTSASLYIRPTFIGIEPSLGVKKPSKALLFVILSPVGSYFSNGTFSPVSLWANPKFVRSWKGGTGDFKMGCNYGSSLLAQCEAAENGCHQVLWLYGKENRITEVGTMNLFLYWINKD-GEEELATPPLDGVILPGVTRQSILELGEEWG---EFKVCERHITMDDLSTALEENRVKEMFGSGTACVVCPVASILYKGQMLHIPTM--ENGHKLSSRIMAKLTDIQYGRIKS-EWTLELP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35855-1", "uniprot_id": "BCAT2_MOUSE", "id": "O35855-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "----------------------------------MAAATLGQVWARKLLPVPWLLC-------------GSKRCVSSIFKAADLQIQMTK--EPQKKPAPSQALLFGKTFTDHMLMVEWNNKA-GWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGDSMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHED-GVLELVTPPLNGVILPGVVRQSLLDLARTWG---EFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQLHIPTM--ENGPELILRFQKELKAIQYGASAH-DWMFRV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35854-1", "uniprot_id": "BCAT2_RAT", "id": "O35854-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "----------------------------------MSAAILGQVWTRKLLPIPWRLC-------------VPGRCVSSNFKAADLQVQVTR--EPQKKPAPSQPLLFGKTFTDHMLMVEWNSKT-GWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGRDKQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLFVILCPVGSYFPGDSMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQQEAQKKGCEQVLWLYGPDHQLTEVGTMNIFVYWTHED-GELELATPPLDGIILPGVVRQSLLDLARTWG---EFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQLHIPTM--ENGPELILRFQKELKAIQYGTSAH-DWMLRV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15382-1", "uniprot_id": "BCAT2_HUMAN", "id": "O15382-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "----------------------------------MAAAALGQIWARKLLSVPWLLC-------------GPRRYASSSFKAADLQLEMTQ--KPHKKPGPGEPLVFGKTFTDHMLMVEWNDK--GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHED-GVLELVTPPLNGVILPGVVRQSLLDMAQTWG---EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTM--ENGPELILRFQKELKEIQYGIRAH-EWMFPV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYD5-1", "uniprot_id": "Q9VYD5_DROME", "id": "Q9VYD5-1", "name": "Branched-chain-amino-acid aminotransferase", "aln": "MTTKMAINAKDIFRNQHRLIRFLEQSIRLCSNQSLKAAQAAQLQQKSSADFEITASLDAQYTSAP-EPIKHDKNLGHQFRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAAKVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSEWVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWPGGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQ-GEQELVTPPLSGLILPGITRDSILRMTRQWG---KFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISYLGQDLYIPTM--EQEKPVHELIRETLTDIQYGRVDH-PWAVVID---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38891-1", "uniprot_id": "BCA1_YEAST", "id": "P38891-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "-----------------------------------------MLQRHSLKLGKFSIR---------------TLATGAPLDASKLKITRNP---NPSKPRPNEELVFGQTFTDHMLTIPWSAKE-GWGTPHIKPYGNLSLDPSACVFHYAFELFEGLKAYRTPQNTITMFRPDKNMARMNKSAARICLPTFESEELIKLTGKLIEQDKHLVPQGNGYSLYIRPTMIGTSKGLGVGTPSEALLYVITSPVGPYYKTG-FKAVRLEATDYATRAWPGGVGDKKLGANYAPCILPQLQAAKRGYQQNLWLFGPEKNITEVGTMNVFFVFLNKVTGKKELVTAPLDGTILEGVTRDSVLTLARDKLDPQEWDINERYYTITEVATRAKQGELLEAFGSGTAAVVSPIKEIGWNNEDIHVPLLPGEQCGALTKQVAQWIADIQYGRVNYGNWSKTVADLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * .: : ** .. * ** ****** : : ** *.* * ** :.*.. :**:.:****:**:: : : :*:* ** ** :* * ** *: *::: :*:. * . ** ***:**.:** . *** ***:.: .***.*: . .* * * *:* **.*: *:* **.. : * :* .* .* ***:* ::.:*******:*. : :. * **.*.**.* ** *:.* .:* : . :: : * *: : : ..: * **:***. *.*: * : .. :::* : *: : . : **** * : ", "identical_positions": 119, "similar_positions": 100, "identity": "26.21%" }, { "cls_id": "homologset.agr.SGD:S000001252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UX53-1", "uniprot_id": "TMT1B_HUMAN", "id": "Q6UX53-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "MDILVPLLQLLVLLLTLPLHLMALLGCWQPLCKSYFPYLMAVLTPKSNRKME-SKKRELFSQIKGLT---GASGKVALLELGCGTG-ANFQFYPPGCRVTCLDPNPHFEKFLTKSMAENRHLQYERFVVAPGEDMRQLADGSMDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPYGSW---AFMWQQVFEPTWKHIGDGCCLTR-----------ETWKDLENAQFSEIQMERQPPP-----------------------------------LKWLPVGP-------HIMGKAVK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DD20-1", "uniprot_id": "TMT1B_MOUSE", "id": "Q9DD20-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "MDALVLFLQLLVLLLTLPLHLLALLGCWQPICKTYFPYFMAMLTARSYKKME-SKKRELFSQIKDLK---GTSGNVALLELGCGTG-ANFQFYPQGCKVTCVDPNPNFEKFLTKSMAENRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQSPRKVLQEVQRVLRPGGLLFFWEHVAEPQGSR---AFLWQRVLEPTWKHIGDGCHLTR-----------ETWKDIERAQFSEVQLEWQPPP-----------------------------------FRWLPVGP-------HIMGKAVK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X9G9-1", "uniprot_id": "G3X9G9_MOUSE", "id": "G3X9G9-1", "name": "", "aln": "MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFPYFLKRFAMIYNWKMA-SLKQELFSNLQEFA---GPSGKLTLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRQLQFERFVVAVGEDMHQVTDGSVDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTW---NYFWQQVLARVWFLAFDGCNLTR-----------ESWKAIEQANFSKLNLQHIQAP-----------------------------------LPLTLVRP-------HIYGYAVK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A343-1", "uniprot_id": "A0A8I6A343_RAT", "id": "A0A8I6A343-1", "name": "", "aln": "MTLAILALRLVVCTLSFPLFLLNLIGVWSWVCKRCFPYFLKRFTVMYNEQMA-TRKRELFSNLQEFA---GPSGKLSLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRHLQFERFLVAVGEDMHQVADGSVDVVVCTLVLCSVKSQEKILREVCRVLRPGGAFYFMEHVADERSTW---NYFWQQVLDPVWFLVFDGCNLTR-----------ESWKTLEQASFSKLKLQHIQAP-----------------------------------LSWALVRP-------HIYGYAVK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8H3-1", "uniprot_id": "TMT1A_HUMAN", "id": "Q9H8H3-1", "name": "Thiol S-methyltransferase TMT1A", "aln": "MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMA-SKKRELFSNLQEFA---GPSGKLSLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTW---NYFWQQVLDPAWHLLFDGCNLTR-----------ESWKALERASFSKLKLQHIQAP-----------------------------------LSWELVRP-------HIYGYAVK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38892-1", "uniprot_id": "CRG1_YEAST", "id": "P38892-1", "name": "Probable S-adenosylmethionine-dependent methyltransferase CRG1", "aln": "--------------------------------MPKTSYLNKNFESAHYNNVRPSYPLSLVNEIMKFH---KGT-RKSLVDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLDKKIRFINAPGEDLSSIRPESVDMVISAEAIHWCN-LERLFQQVSSILRSDGTFAFWFYIQPEFVDF---PEALNVYYKYGWSKDYMGKYLNDNQREILLNYGGEKLRSLLSDRFGDIEVTIYSPSDPNASTVTAENSQFLWRAAITLNQFKEFVKSWSIYTSWARDNPSKPD-IADIFINELKEICHCEDLNVPLKIEWSTFYYLCRKRE--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q1LYP9-1", "uniprot_id": "Q1LYP9_DANRE", "id": "Q1LYP9-1", "name": "", "aln": "---------------------------------MAVRLFEGKEHANSYWKYRISPSEELIGKVLQFHRNNEYSSNGLAVDVGCGSGQGTLLLAPHFTRVVGTDISPAQLEMGRKHVN----IPNVSFRESPAEELP-FEDGSVDLVTAMSAFHWFD-HSRFLQEADRVLKPHGCLALLNYTLDMELTYGNCSEALNLICNEFYAALHPLRDPHLG----------PSSFELYKRTYDSLQYPVKEWHDLFWVKKAVPLSGYIG-----------MVKSFSTFQTLLKTDPEEARRLSQGIEDRLKRAMDVTSSETEVIMGVKYFYFLAQKPAND", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .*..:: : : . :::***:* ..: . * .* * .. .: * * : .*:: . *:*:* . .: . :.:::. :*:. * : : : : : . : :..:: * . :* ", "identical_positions": 18, "similar_positions": 58, "identity": "5.39%" }, { "cls_id": "homologset.agr.SGD:S000001253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K157-1", "uniprot_id": "GALM_MOUSE", "id": "Q8K157-1", "name": "Galactose mutarotase", "aln": "-MVSVTRTVFG-----ELPSGGGTVEKFQLR-SDQLSVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQ-KQPYFGAVVGRVANRIAKGRFTIGGKEYHLPV-NRE-PNSLHGGFTGFDKVLWTPQVLT-NGVQFFRVSPDGE----EGYPGELKVWVTYTLDGGE----LVINYRAQASQTTPVNLTNHSYFNLAGQGS--PNIYDHEVTIAADAYLPVDETL-IPTGVIAPVEGTAFDLRKPVELGTHLQDYH---IHGFDHNFCLKES---KEKKFCARVRHAASGRILEVYTTQPGVQFYTGNFLDG------TLKGKNGAVYPKHSGLCLETQNWPDSVNQPQFP-PALLRPGEEYNHTTWFKFSVA--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG4-1", "uniprot_id": "GALM_RAT", "id": "Q66HG4-1", "name": "Galactose mutarotase", "aln": "-MVSVTRTVFG-----ELPSGGGAVEKFQLR-SDQLNVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQ-KQPYFGAVVGRVANRIAKGRFTVDGKEYHLPI-NRE-PNSLHGGFRGFDKVLWTPQVLS-NGVQFSRVSPDGE----EGYPGELKVWVTYTLDGGE----LVVNYRAQASQTTPVNLTNHSYFNLAGQGS--PDIYDHEVTIAADAYLPVDETL-IPTGVIAPVEGTAFDLRKPVELGKHLQSYH---IHGFDHNFCLKES---KEKKFCARVHHAASGRILEVYTTQPGVQFYTGNFLDG------TLKGKSGEVYPKHSGFCLETQNWPDAVNQPQFP-PILLRPGEEYNHTTWFKFSVA--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C23-1", "uniprot_id": "GALM_HUMAN", "id": "Q96C23-1", "name": "Galactose mutarotase", "aln": "-MASVTRAVFG-----ELPSGGGTVEKFQLQ-SDLLRVDIISWGCTITALEVKDRQGRASDVVLGFAELEGYLQ-KQPYFGAVIGRVANRIAKGTFKVDGKEYHLAI-NKE-PNSLHGGVRGFDKVLWTPRVLS-NGVQFSRISPDGE----EGYPGELKVWVTYTLDGGE----LIVNYRAQASQATPVNLTNHSYFNLAGQAS--PNINDHEVTIEADTYLPVDETL-IPTGEVAPVQGTAFDLRKPVELGKHLQDFH---LNGFDHNFCLKGS---KEKHFCARVHHAASGRVLEVYTTQPGVQFYTGNFLDG------TLKGKNGAVYPKHSGFCLETQNWPDAVNQPRFP-PVLLRPGEEYDHTTWFKFSVA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKF7-1", "uniprot_id": "Q9VKF7_DROME", "id": "Q9VKF7-1", "name": "Aldose 1-epimerase", "aln": "MSITVEERNFG-LATNPLTEARQMVHSYTLKNTKGMSVTVIQLGATIQSINFPDGSKKVEDVCLGFDDIAGYVTNKAAYMGGTLGRVANRVASGGFTLDETTVNLTR-NVEGQFHLHGGFLGFDSVIWEVVQKTPQGVVFRHESQHGH----EGYPGILTCLITYRLDNEDR---LSISFEATTDRQTIVNLSNHAYFNLAGHNAGPKGLAEHTVEIASSEIVETDDRQ-IPTGELTLVDNTAYDLRSPVVLGDRLKQFENCPIQGFDNCYVVNGGQLLRSTVKVAKIVHPPSGRALEVWTNQPGIQFYTANNITK-------ITGKKGLFYVKHGALCVQTVKFPDAINHQNFP-SINLNPNETYRHEVVYWFKVEKTCRCCYKK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP02-1", "uniprot_id": "Q9VP02_DROME", "id": "Q9VP02-1", "name": "Aldose 1-epimerase", "aln": "MSITLEEEIFG-LAVNPFTKSPEMVRRYTLKNSKGMTVSVIQLGAIIQSVCLPDAYKKVDDVCLGFDDIASYLANKGAYIGGTLGRVANRVANGEYTFNDTKVSVTK-NIQDKFQLHGGFIGFDSVIWEVVQKSAEGVIFRHVSPHGH----EGYPGKLTCLITYQLDNENR---LWVRYEATTDRSTMVNLSSHAYFNLAGHGSGAKGLSEHTVEIASDQIVDTDELQ-IPTGKLVDVKDTVFDLRLPVLMRDRLMQFENRQIKGYDNCFVVNGGRVQKSVAKVAKIVHPPSCRVLEVWTDQPGMQFYTANNLTS-------IVGKNCTKYEKHGSFCVETEKFPDAMNHPEFP-SISLEPNEKYRHDVLYWFKVEESWKCCCNNDP---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY83-1", "uniprot_id": "Q9VY83_DROME", "id": "Q9VY83-1", "name": "Galactose mutarotase", "aln": "-MVKVVEDIFG-IATNPFTKQAQVIRRYTMTNTNRLSVAIIQLGATIQSIQVPDAYHQLSDVVLGFDDVAGYTKYRNYHFGCTIGRVSDVVGNGEFIMDERRVVVSK-NLGQKHQTNGGFVGFDQVIWDLEMKRPDGVTLRHISPDGH----EGYPGTLKVLLHFTINDDNR---FFIQIEATTNQTTPVNISNHIIFNLAGQSTGIKGIFDHQINIEAIETMETSNGDGLPTGRFKNVNDSVYDIRLPVFMGDRVRQFEKKPVKGYDVCFALDKEFDAIRTRYVGRFLHPDSGRFMEIFSNQPCVKFTTGNCFPQEPLGEPPILGKKCTRYWQHCGFSLQLLNYPDAVNQPDFP-RIFINPGEHYFHETIYHFGVQESWKCCADPEELEALGEEPLRKPKAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRU1-1", "uniprot_id": "Q9VRU1_DROME", "id": "Q9VRU1-1", "name": "Aldose 1-epimerase", "aln": "-MVNVTEDVFANGAVNPFTKSKDTIKRFTLTNGAGMSVQLITRGATITSIKTPDASGQIDDVTLGFDDLAGYQSERNPYFGATIGRVCNRIANGSFYLDGKLVQVSK-NRDNKFQLHGGFVGFDKAHWEVVEVRVDGVTLSHTNPDGH----EGYPGKVTATASFTLSEDNC---LHVQMSALADKTTPVNLTNHSYFNLAGHKSGANGLYEHTIEINAYGITETDQSS-IPTGRITPVEGTGFDLRVSSNLGERLKALQ--PARGYDDNFCVTFS-PPQPLAKVARATHPPSGRWLEVVSNQPGVQFYTSNFMPDVERGESPIPGKDGAAYAKHCAFCLETQKFPDSVNHSNFP-STILRPGESYQHEVIYKFGVSH-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38893-1", "uniprot_id": "YH10_YEAST", "id": "P38893-1", "name": "Uncharacterized isomerase YHR210C", "aln": "---------------MSNNKAGGEYEVITIGDAKKLQATISELGATLLDLKVNN-----ESIVLGYPDIHGYISDGYNYIGATVGRYANRIYKGMFSMEDGPHQLTVNNCGNTNHSSISSFHLKKYKASKVQNPLDDLYIVEFTLLDDRTLPNEFPGDLAVNLKYTLNVADMTLDLEYEAKLVSGEATPINMTNHTYFNLN-KTMDKKSISGTEVRLCSDKSLEVSEGALIPTGKIVQRKIATFDSSKPTILQDDGPIYDYAFIVDENKNLKTTDSVSVNKLVPAFKAYHPASRLSLEVSTTEPTVLFYTGDNLCDG--------------FTPRSGFAVEQGRYVDAINRDGWRDCVLLRRGEVYTSKTRYRFAV---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : *. : : : ..: **: :: .* ::* .:** .: : .* : . :. * . :.. :.: : . . .. : :** : : :. : : :.. * :*::.* *** : .: : : : ..: :*** . . : :* . : . . : : *. * :*: : :* : * *.: : : : .:.:: .: *::*: : :. .* * . : * * ", "identical_positions": 33, "similar_positions": 103, "identity": "8.19%" }, { "cls_id": "homologset.agr.SGD:S000001258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2L6-1", "uniprot_id": "MINP1_MOUSE", "id": "Q9Z2L6-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "-MLRGARSHLPASVAPAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDANPWLLVDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLKQLQGLLQTRE-------SRDGGSQ------VAAALAEWPLWYGDWMDGQLVEKGRQDMRQLALRLAALFPDLFSRE-NYDRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECGPPRINDKLMRFFDHCEKFLTDVERNETALYHVEAFKTGPEMQKVLKKVAATLQVPMNSLNADLIQVAFFTCSFDLAIKG----------VHSPWCDVFDVDDARVLEYLNDLKQYWKRSYGYTINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVNRKFRSGHIVPYASNLIFVLYHCDNAQSPEEQFQIQLLLNEKVLPLAHS---QRPVGLYEELKTHYRDILQSCQTSKECSPPKANITSDEL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35217-1", "uniprot_id": "MINP1_RAT", "id": "O35217-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "-MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRE-------SVDGGSR------VAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRE-NYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAIQG----------VHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSSVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHS---QKTVALYEDLKNHYQDILQSCQTSKECNLPKVNITSDEL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNW1-1", "uniprot_id": "MINP1_HUMAN", "id": "Q9UNW1-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "-MLRAPGCLLRTSVAPAAALAAALLSSLARCSLLEPRDPVASSLSPYFGTKTRYEDVNPVLLSGPEAPWRDPELLEGTCTPVQLVALIRHGTRYPTVKQIRKLRQLHGLLQARG-------SRDGGASSTGSRDLGAALADWPLWYADWMDGQLVEKGRQDMRQLALRLASLFPALFSRE-NYGRLRLITSSKHRCMDSSAAFLQGLWQHYHPGLPPPDVADMEFGPPTVNDKLMRFFDHCEKFLTEVEKNATALYHVEAFKTGPEMQNILKKVAATLQVPVNDLNADLIQVAFFTCSFDLAIKG----------VKSPWCDVFDIDDAKVLEYLNDLKQYWKRGYGYTINSRSSCTLFQDIFQHLDKAVEQKQRSQPISSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNYKKQMHRKFRSGLIVPYASNLIFVLYHCENAKTPKEQFRVQMLLNEKVLPLAYS---QETVSFYEDLKNHYKDILQSCQTSEECELARANSTSDEL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W438-1", "uniprot_id": "Q9W438_DROME", "id": "Q9W438-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "-MLSQFYCLF---LLLLHFFVGVTLSEEGECRRLNRAD-----IEGRLSTKTPYRAIANYDETPPKYAG---------CHPTRIWTIIRHGTRNPSESVILQAQNRLSEIKKRI-------LDQTKPPICTAELEKLRQWHWMHLNATEDEKLLVAEGEDELIELAERMQRRFPDLLPELYNPEWYYFKYTATQRTLKSAESFATGLFGRHR-------IHTVRYPPPLHEDPVLRFYKGCGKWKTDVDKNPETLVNARRFLAEPQMQSAVEQVRSSTRLP--DLQPEDVQLMYTVCAFETAWHRPRHDSGSKSSYESVWCNFFDVAALEALEFFEDLEYYWNDGYGYELTHRIACPAIADMFAAISSSEETRQRR----ANATLYFTHSGTLLKLLAHLGLARDNKPLTHKHFAS--ERLWRTSQIDAFATNLAFLRYDCDKGNP-----QVLVLHQERVVRLPGCPQ-DKDLCPLATLRRIYANSVDHCDREKMCRV---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VV72-1", "uniprot_id": "MINP1_DROME", "id": "Q9VV72-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "-----------MRLLILLLLPLVAIAQDDYCFSKDTSR----LQTRQFSSKTAYQIVKGTDIDKQYLVPG--------CQPQKMWIFHRHGTRLPKKSMINKASRVAELRDLIINNYQVARTKPETDALCQTDLIAIKLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYPTVLTANYNDTYYQFRHTDTQRTTESFKAFAEGLFGSQN------AAHPVEIP---KQDLLLRPYDYCSSFKNVNYKDEGSEY--YKFHQSKLYNDTLADISTRLGFLY-TLEEADIKLMYDMCRYEQAWNVD---------RNSVWCGAFLPEQITVFEYLEDLKYYYGSGYGFPENAHLNCRLVQDLLTHLSNPVS---------PHVVAHFGHSTGLLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDCPADLDRE---KVVFFLNQQAVQLDWC---SVGLCKWSDVLEKYKTIADADCGEYYCRTGGAPSLGSGVGGLLATTLAAMLVYLMH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38693-1", "uniprot_id": "PPAC_YEAST", "id": "P38693-1", "name": "Acid phosphatase PHO12", "aln": "MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPES---------------CEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTG-----QFSGALSFLNDDYEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFN------ISLQTISEAESAGANTLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKGLN--------LTSSDANTFFAWCAYEINARG-----------YSDICNIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQ-------KVWLSFTHDTDILNYLTTIGIIDDQNNLTAEHVPFMENTFHRS-WYVPQGARVYTEKFQCSNDTY------VRYVINDAVVPIETCSTGPGFSCEINDFYGYAEKRVAGTDFLKVCNVSSVSNSTELTFFWDWNTKHYNDTLLKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::. . * * :: . *** * *. . . . . : . : . * . : .:* .: * ** . : .. * : : : . * : : * :: . * *. * :.: :**: *: . *: . . . :... . * * :* *: :* *. * : :: . .:.. :.* : . :: .: : . . * ", "identical_positions": 31, "similar_positions": 77, "identity": "5.89%" }, { "cls_id": "homologset.agr.SGD:S000001259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24547-1", "uniprot_id": "IMDH2_MOUSE", "id": "P24547-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGG-TSYVP--------------DDGLTAQQLFNC--GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU28-1", "uniprot_id": "IMDH2_RAT", "id": "E9PU28-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGG-TSYVP--------------DDGLTAQQLFNC--GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNESDELVAIIARTDLKKNRDYPLASKDT-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHGLHSYEKRLF------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12268-1", "uniprot_id": "IMDH2_HUMAN", "id": "P12268-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGG-TSYVP--------------DDGLTAQQLFNC--GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXP9-1", "uniprot_id": "IMDH2_DANRE", "id": "B0UXP9-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGQ-TGYVP--------------DDGLTGQQLFNS--GDGLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTESGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKARHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDS-RKQLLCGAAIGTHNDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLIDAGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAKALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMD----KNLGSQTRYFSESDKIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTMSAQMEGGVHSLHSYEKRLF------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50096-1", "uniprot_id": "IMDH1_MOUSE", "id": "P50096-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGG-TGYVP--------------EDGLTAQQLFAN--ADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDS-HKQLLCGAAVGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLZ7-1", "uniprot_id": "IMDH1_RAT", "id": "D3ZLZ7-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGG-TGYVP--------------EDGLTAQQLFAN--ADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDS-HKQLLCGAAVGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20839-1", "uniprot_id": "IMDH1_HUMAN", "id": "P20839-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGG-TGYVP--------------EDGLTAQQLFAS--ADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS-QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGV1-1", "uniprot_id": "IMDH3_DANRE", "id": "Q5RGV1-1", "name": "Inosine-5'-monophosphate dehydrogenase 1b", "aln": "--------MADYLISGG-TGYIP--------------DDGLSAQQLFAV--GDGLTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLEAKVRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGVTLKEANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDS-RKQLLCGAAIGTREDDKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVKALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KNTSSQKRYFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEKRTMSAQVEGGVHGLHSFEKRLY------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6GMG5-1", "uniprot_id": "IMDH1_DANRE", "id": "Q6GMG5-1", "name": "Inosine-5'-monophosphate dehydrogenase 1a", "aln": "--------MADYLISGG-TGYVP--------------EDGLTAQQLFAI--GDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKVRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLKEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDS-RKQLLCGAAIGTREDDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KNNSSQKRYFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTMSAQVEGGVHGLHSYSFLPFTRNGYIEPGSRGHPRAGPNVPSPAVTKHSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07152-1", "uniprot_id": "IMDH_DROME", "id": "Q07152-1", "name": "Inosine-5'-monophosphate dehydrogenase", "aln": "MESTTKVKVNGFVESTS-SSAAPAIQTKSTTGFDAELQDGLSCKELFQN--GEGLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFR-ENQPEVLLADIMTT--ELVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDS-NKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38697-1", "uniprot_id": "IMDH2_YEAST", "id": "P38697-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "-----MAAIRDYKTALDFTKSLPR-------------PDGLSVQELMDSKIRGGLTYNDFLILPGLVDFASSEVSLQTKLTRNITLNIPLVSSPMDTVTESEMATFMALLGGIGFIHHNCTPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKEKYGFAGFPVTTDGKRNAKLVGVITSRDIQFVEDNS--LLVQDVMTK--NPVTGAQGITLSEGNEILKKIKKGRLLVVDEKGNLVSMLSRTDLMKNQNYPLASKSANTKQLLCGASIGTMDADKERLRLLVKAGLDVVILDSSQGNSIFELNMLKWVKESFPGLEVIAGNVVTREQAANLIAAGADGLRIGMGTGSICITQEVMACGRPQGTAVYNVCEFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCRSLTLLKNNVQRGKVRFEFRTASAQLEGGVHNLHSYEKRLHN-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : : * ***: ::*: ************ :** :.:*.* : **:.:*:. **:*********: ** *** ****:******** ** *::**.:::**: :* *:** * :. . : : ** * *:* * ..:*:*:::****:* :.. : : ** : *... *:.* .* **:: ***:* :*:: . **::::**** * :.:* ***.: **** **::** . ** ** ** * *:::********:::: *::::*:.:* ::*:.***** ** *** **.*.**:*** *********:*** **.*:**:*. :*.:**** :****:*.:**:.**::**:*:****.:**.*:*:*****:.** *** ******::**: * . *..* *.: :******:: ****: :::*** *:**.*****..*:. :: : *:::* ** ***:**.**.*.*:. . ", "identical_positions": 247, "similar_positions": 157, "identity": "43.03%" }, { "cls_id": "homologset.agr.SGD:S000001263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIU1-1", "uniprot_id": "ABTB1_RAT", "id": "Q5XIU1-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQG-IHSDVVF-VVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPPELRGDLGELPFPCPDGFSSCPDICFRVADSS-----FLCHKAFFCGRSDYFRALLDDHFRESEEPVASGDP--------PVVTLHDISPDIFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQ---LLEEDSVVGVWRIAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQQLRALENLLVSIGLDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ2-1", "uniprot_id": "ABTB1_MOUSE", "id": "Q99LJ2-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQG-IHSDVVF-VVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPSELRGDLGELPFPCPDGFSSCPDICFRVADSS-----FLCHKAFFCGRSDYFRALLDDHFQESEEPAASGDP--------PVVTLHDISPDIFIHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQ---LLEEDSVVGVWRIAKMFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQRLRALEDLLVSIGLDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969K4-1", "uniprot_id": "ABTB1_HUMAN", "id": "Q969K4-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "aln": "-------MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQG-IHSDVVF-VVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCS-----FLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGP--------PAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQ---MLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYS------------------AIEEAQQRLRALEDLLVSIGLDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40560-1", "uniprot_id": "YIA1_YEAST", "id": "P40560-1", "name": "Ankyrin repeat-containing protein YIL001W", "aln": "MADKLMDKNFEELCYSCRTGDMDNVDRLISTG-VNVNSVDKFDNSPLFLASLCGHEAVVKLLLQRGAVCDRDRYEGARCIYGALTDTIRDTLLSYDISKAVDVKQPFATHISSMYNDEGFLKRDITFRVSNGKLFTAHKFLLCARSEILAEKMVNEWAKHEIVSL---EVRPDIFDIFLKFLYLIPILHQIE-PGQYEELIELSSKFDI--ELLPEFLDKARHTADPTEKSRLMSDYQYKFTEVARSQLLIFVNNCIFRSTVDLANSERRVFSLMNCPAYPDVQLMVKNRNGAIRIYPCHLAVLS-RAEYFKVMFTNNFKEKVTYIKAKHVTGKYNSIIPQLTLPNCEFEVAEIILRYLYADNTDIPWMYAVDVLLLADILLEDRLKTIASTIITQSKEFIQQYNVFDVLYLSWEIGVERLEQFAAKFIAIHLQELYKDPEIKRAIMLSSQRISLRQETDTIELVDDIRYYLLRKYSFEPDDVELFENQDDLEYLKQVGYLEYRKDMGMLDNILADLELDV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* ***.**:..* *:. *:** **:*.:**: *.***** :* ** .** *: : ::* **:****:*.** :* .*. .* :: : .: . ::* :: *:.* * :** * .*: :* *** :*: : .:* :.:* * :.* *. :*::** : :* .: *.* : .. :*: :* .: . :...*. . .. : : :: : :: :* : . : * . . . : **: : * . . : ** *.:. *::**:.:: ::*:*. : * :** . . :: :* *:*:*:*::. * *** :**: * ** :.. ::* :::: .*..* :: : : ***: .::::* :::* : :: .*: .: :: *****:* ******::: . . . . * :: : *:::*..: ** ", "identical_positions": 124, "similar_positions": 179, "identity": "23.8%" }, { "cls_id": "homologset.agr.SGD:S000001264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHC4-1", "uniprot_id": "SYNJ1_MOUSE", "id": "Q8CHC4-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-------------MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAE--KEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRVDASD----------------EDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD--NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGS-HRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKASEHASDIHMVSFDYHQMVKGGKAEKLHSILKPQVQKFLDYG-FFYFDGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTIS---RDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQESTFFDDALIDELLRQFAHFGEVILIRFVEDKMWVTFLEGSSALNALSLNGKELLNRTITITLKSPDWIKHLEEEMSLEKISVTLPSSAS-STLLGEDAEVA-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTVPEYSAPSLPIRPSRAPSRTPGPPSS-----------QGSPVDTQPAA---QKDSSQTLEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVARREIEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPAGYGAARPTIPARAGVISAPQSQARVCAGRPTPDSQSKPSETLKGP-AVLPEPLKPQAAFPQQPSLPTPAQKLQDPLVP--------------IAAPTMPPSGPQPNLETP---------PQPPPRSRSSQSLPSDSSPQLQQEQPTG-QVKINGISGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSVQISPVLTPDPKM-LIQLPSASQSQVNPLSSVSCMPTRPPGPEESKSQESMGSSANPFPS-LPCRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVPNSPFPPLMPLSHDTSKASSSLGGFEDNFDLQSQSTVKTSNPKGWVTFDEDDNFPTT--GKSKSVCPDLVGNAPASFD-------DDWSKGASVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLPSKAPSTLDFTER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62910-1", "uniprot_id": "SYNJ1_RAT", "id": "Q62910-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-------------MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAE--KEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRVDASD----------------EDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD--NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGS-HRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKASEHASDIHMVSFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFDGSA-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTIS---RDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQENTFFDDALIDELLQQFAHFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITITLKSPDWIKTLEEEMSLEKISVTLPSSTS-STLLGEDAEVS-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTAPEYSAPSLPIRPSRAPSRTPGPLSS-----------QGAPVDTQPAA---QKESSQTIEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVTRREMEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPSGYGAARPTIPARAGVISAPQSQARVSAGRLTPESQSKPLETSKGP-AVLPEPLKPQAAFPPQPSLPTPAQKLQDPLVP--------------IAAP-MPPSIPQSNLETP---------PLPPPRSRSSQSLPSDSSPQLQQEQPTGQQVKINGACGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSAQISPVLTPDPKM-LIQLPSASQSKVNSLSSVSCMLTMPPVPEQSKSQESVGSSANPFPS-LPTRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVSNSPFPPLMPLSHDMSKPSSSLDGFEDNFDLQSQSTVKTSNPKGWVTFDEDEDFPTK--GKSRSVYPDSLGNTAASFD-------DDWSKGTNVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLSSKASPTLDFTER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43426-1", "uniprot_id": "SYNJ1_HUMAN", "id": "O43426-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-------------MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAE--KEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSD----------------EDRISEVRKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTD--NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQVGS-HRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFNGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTIS---RDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKS-SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTS-STLLGEDAEVA-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-----------QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS------------PQAGLAG-------PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS-TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP--------------VAAP-MPQSGPQPNLETP---------PQPPPRSRSSHSLPSEASSQPQ--------VKTNGISDGKRESPLKIDPFEDLS----FNLLAVSKAQLSVQTSPVPTPDPKR-LIQLPSATQS--NVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVK--GKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPP--PVPLLPPGTSPPVDPFTTLASKASPTLDFTER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N6-1", "uniprot_id": "A0A8M2B1N6_DANRE", "id": "A0A8M2B1N6-1", "name": "Synaptojanin-1", "aln": "-------------MAFSKGYRIYHKLDPP-PYSVIVETRNREECLMFESGAVAVLSAAE--KETIKASYTKMLDAYGILGVLRLNLGDSMLHSLVVVTGCSSVGKVQDSEVFRVTGTDFVSLKNDPTD----------------EDRIADVRKVLNSGNFYFAWSSTGVSLDLSLNAHRRIREDTSD--NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAGHKQAKACVISRLSSERAGTRFNVRGTNDDGQVANFVETEQIIFLDDKVSSFIQIRGSIPLFWEQPGIQVGS-HRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLLGMKEGEHMLSKAFQSHLKASEHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMGLTEKPQLVARFQEVFRSMWSTNGDSISKIYAGTGALDGKAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDILRLGSTLNSDLADKARALLTTSSLYVSEPILQS---------ASPRVLLGMCQNHFKYTRPKKIRVCVGTWNVNGGKQFRSIAFRNHTLNDWLLDAPKKAGHPEFQDVKNNPVDIFAIGFEEMVELNAGNIVSASTTNQKLWAAELQKNIS---RDQRYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGGVAIRMLFHTTSICFVCSHFAAGQSQVKERNDDYNEIARKLSFPMGRLLYSHDYVFWCGDFNYRINIPNEEVKELIRQQNWDALIGGDQLVEQKNAGQVFRGFIEGKLDFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWKRRKWNFDKTAEELELNVVGAPVNEEEQYPWSPGDLKYYGRAELKTSDHRPVVAIIDVDILEVDPEARHQVYKEVIALQGPPDGTILVSLCS-SGPDD-YFDDALIDDLLDKFANFGEVILIRFVEEKMWVTFLEGYSALAALSLSGSTVNGKTIDIRLRSPGWIKSLEEEMSVERICGSIPTSTS-STLLAENSDLG-EEYDMEGDVD---EEVEDILPQHLQPGAGMDLSASPATSPRTSPCPSPTHG---EPAPPIRPSRAPPRTAGPPQGGLSPASIRRELAGSPVDGQPAG----APFSQGLEPKRPPPPRPNAPPARPAPPQRPPPPSGGRSPTPVRKDSAGFAEPLNLEFDLTDNEGQKSPALARADAAGRGQATGPAPGGIPRPIPPRAGVISVTPQARPPPPAHPGAPRPTAEVHPGAP-RPSPDNHPGAPRPTAEPQSKPSELPLGPPPTLPGPVRPQMTSPMQPQSVSPVQPPVQPQLPPPIQSQLPPPMQPTLPAPLMPQQAPQTSAGAAAAPQPGLASPKPPPRSRSSHALPPESAPAPT--------TQAKNMNGVQREAQWNLDPFDMLNPQSLFQNTPFTASLPRSSSSSTSTPSPSSSSSTLPSNLSLFSAPDTSSASCLLAPPAPSRSKSQETLRCSPNPFLTDIQPR-PNSTNPFTSGLQFSPRRS---LTPDFYTQMQASKPDFNRAMSAVGHSSTLPPTFS--RQQSLVTATAPAPNKQTQKWVTFDDDLDFLSKRVGTGPLASPLPFPQTQSSFP--------SSGFGMDNNWASLPTSAFPAIPPPVPTR----TNTSIKNAQLPSRN----DFTER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D2G5-1", "uniprot_id": "SYNJ2_MOUSE", "id": "Q9D2G5-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "-------------MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEE--KEVIKGLYSKLTDAYGCLGELRLQSGGVPLSFLVLVTGCMSVGRIPDAEIYKITATELYPLQEEAKE----------------EDRLPTLKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDGSEWG-TSFFWNQLLHVPLRQHQVNCHN----------WLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQTIYMDDGVSSFVQIRGSVPLFWEQPGLQVGS-HHLRLHRGLEANAPAFERHMVLLKEQYGKQVVVNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLQLHWEDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-IIDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALL-----------------ATPRILKAMTERQSEFTNFKRIQIAVGTWNVNGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQD-DGSPADVFAIGFEEMVELSAGNIVNASTTNRKMWGEQLQKAIS---RSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLMEFDQLQLQKSSGKIFKDFHEGAVNFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDPQIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELLRKRDSMAPVSPTANSCLLEENFDFSSLDYESEGDVLE---EDEDYLVDGFGQPVVSDSELGGDNSSDTMSSLTPASK---SPALAKKKQHPTYK------------------------------------------------------------------AGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYN----------VKQIKTTN--------AQEAEAAIRCLLEASGGVP-----ESAPGAIPLRNQGSSKP-EATLGP-PALPRRPAPRVPTMKKPTLRRTGKPMLPEENFE-------------PQPVHFTMASQEMNLETP-----------PPITATPIPPVPKPRTLQPG-----------KGVEG--RPSSGKPEPDEAPS-----VTGTVESPPPEAQEAPSLAPKVPP-------------RRKKSAPAAFHLQVLQNNSQVLQGLTCSSS------------SPPSLKPDTHPLCLQVALGTSSARSPETHGPRVTEPEAASFHGNYP----------DPFWSLLHHPKLLNN-TWLSKSSEPLDVGSR--------NPERTHTEPAQVN------------------ASLAERGLPPDHGGKDLSHWVTASNKDKRTTLGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55207-1", "uniprot_id": "SYNJ2_RAT", "id": "O55207-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "-------------MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEE--KEVIKGLYGKPTDAYGCLGELSLKSGGVPLSFLVLVTGCTSVGRIPDAEIYKITGTEFYPLQEEAKE----------------EDRLPALKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDCSEWG-TSFFWNQLLHVPLRQHQVNCHD----------WLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQAIYMDDGVSSFVQIRGSVPLFWEQPGLQVGS-HHLRLHRGLEANAPAFERHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLKLHWDDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-ITDRFVESFKAMWSLNGHGLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLGLGSNKQNSLSGMLDGKATPRILKAMTERQSEFTNFKRIQIAMGTWNVNGGKQFRSNLLGTTELTDWLLDAPQLSGAVDSQD-DGGPADIFAVGFEEMVELSAGNIVNASTTNRKMWGEQLQKAIS---RSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLMEFDQLQLQKSSGKIFKDFHEGTINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDANIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVIVNLQSPTLEERNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDVLE---DDEDYLADEFGQPVVSDSELGGDDSSDTMSASTPASK---SPALAKKKQHPTYKDDADLMT-------------LKLELEVAGNFRHRSPSRSLSVPNRPRP--------PHPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYN----------VKQIKTTN--------AQEAEAAIRCLLEAGGGVP-----ESAPGATPLRNQGSSKP-EASLGP-PVLPRRPVPRVPTMKKPTLRRTGKPMLPEEQCE-------------QQPVHFTMASQEMNLETP-----------PPITA-PIPPVPKPRTFQPG-----------RGVER--RPSGGKPEPDDAPP-----VTGAVELSSPEAPEAPSLAPKVPP-------------RRKKSAPAAFHLQVLQSNSQLLQGLTCSSS------------SPSPPKPDTPLLYPQMALGTSSAISPETDGPRVTEPEAASFHGDYP----------DPFWSLLHHPKLLNNNTWLSKSSEPLDLGSR--------TPERTHTDSAQVN------------------ASVVERGLPPDHGGKDFSHWMAASNKDKRTTLGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40559-1", "uniprot_id": "INP51_YEAST", "id": "P40559-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51", "aln": "MRLFIGRRSRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIFNGLLGLVCLNGDIYVAVISGVQNVGFPRWKLIDHQVRPSESIYKVLDVDFYSLENDVFDYLLCERSEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSHNLEYTVDNQDLSFIWNANLASEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSES---QEKLALTYKDCAESKGIKITNIEYSSSVLTKSPHKLLYLLK---QDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELT---SPFLDAHDKLWSENYYWLDRTYTKHTKNSGKYT-------------KVYSKLFGSR-------VRLYDPLHIYISQYLKQLRS------------------------------------KYTFEKDISIFAGTFNISG-------KIPKDDIKDWIFPKSMSK--------EDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGE----------------------------VLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKK-------TTLGTQIYEKIMERLEG-------------LDDDEKIAVLSDDAFVIESFEGSDSIAGPTHSPTPIPEPKRGRKLPPPSSDLKKWWIGSGKQVKVVLDVDPAVYMINPKRDPNPFVEN--------------------EDEPLFIER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: :* . * . : .: ::: . : *:. . *. . : . * : : . . . . .:::: .:: .*. : : *. ::*::..* **:: : . : *:** * : : : : :* :: * : . : *. :***:* * : .* .:**:*: ***** : :. : *: *:.**:*****. *: ::::: :. **:**: *. ** ::*:: : . .. : . .: : .::: . . . .** :*: . : . . *.*.:* ..:*.:::.*:*: ::. *:* : :.: . . * : . :** * :.: :: .** . .: .::*.. : : . : :: : * ::: * * : **:*:.* : . :.**:: . . .*::.:*:**:***..*::: :.. :::* :: . :. *.::*: * * ** *: * :*:. . . ::.: *. ***:** :.***.*.: : :* :*.: **::** .:*::*::*: *::.: *. * : .** ::* ******* :. *:* : ::: *: *** * :*: * * * : * ****:* : ****:* * ******:* . * : :: ****** *:. : *: : :: .:: : . : . :::. : . :: .: * : : : . : :. : . . . :: : : * : : ", "identical_positions": 168, "similar_positions": 308, "identity": "9.81%" }, { "cls_id": "homologset.agr.SGD:S000001265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R061-1", "uniprot_id": "NUBP2_MOUSE", "id": "Q9R061-1", "name": "Cytosolic Fe-S cluster assembly factor NUBP2", "aln": "MEAAAGERAEPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLRAQGKAVHQCDNGWVPVFVD--QEQSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDEHMATMEALRPYRPLGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGVPFLGSVPLDSQLTRSLE----EGRDFIQEFPKSTAYSALTSIAQRVVHRMSALCS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FS1-1", "uniprot_id": "NUBP2_RAT", "id": "Q68FS1-1", "name": "Cytosolic Fe-S cluster assembly factor NUBP2", "aln": "MEAAA----EPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLHAQGKAVHQCDSGWVPVFVD--QEQSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGELDYLVVDTPPGTSDEHMATVEALRPYKPLGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFACPHCAECTNVFSSGGGEELARLAGVPFLGSVPLDPQLTRSLE----EGRDFIQEFPKSTAYSALTSIAHKVLHQMPALCS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5Y2-1", "uniprot_id": "NUBP2_HUMAN", "id": "Q9Y5Y2-1", "name": "Cytosolic Fe-S cluster assembly factor NUBP2", "aln": "MEAAA----EPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHAGKKVGILDVDLCGPSIPRMLGAQGRAVHQCDRGWAPVFLD--REQSISLMSVGFLLEKPDEAVVWRGPKKNALIKQFVSDVAWGELDYLVVDTPPGTSDEHMATIEALRPYQPLGALVVTTPQAVSVGDVRRELTFCRKTGLRVMGIVENMSGFTCPHCTECTSVFSRGGGEELAQLAGVPFLGSVPLDPALMRTLE----EGHDFIQEFPGSPAFAALTSIAQKILDATPACLP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3B7Q7-1", "uniprot_id": "NUBP2_DANRE", "id": "Q3B7Q7-1", "name": "Cytosolic Fe-S cluster assembly factor nubp2", "aln": "MDGSG-----KGNLDQVKHVLLVLSGKGGVGKSTITTELALAFRHAGKKVGILDVDLCGPSIPRMLSVGKPEVHQCDSGWVPVYADP-QQQQLALMSIAFLLEDSDEAVIWRGPKKTALIGQFVSDVAWGELDILLVDTPPGTSDEHLAVLENLRKHRVDGAVLVTTPQAVSTGDVRREITFCKKTNLKILGIVENMSGFVCPHCSECSNIFSKGGGEELAKLTGSAFLGSVPLDPLLTESLE----EGRDFLQAFPESSTFTAISHIANTLLNSLNA----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD2-1", "uniprot_id": "NUBP2_DROME", "id": "Q9VPD2-1", "name": "Cytosolic Fe-S cluster assembly factor Nubp2 homolog", "aln": "------------MLDKVKNVIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDDGWVPVYTD--ESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSCTNIFSSNGGVSLATYAQVPHLGTLPIDPRVGILAG----TTTSVLDELPDSTTAEVLTHIVEKLKTMLVS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40558-1", "uniprot_id": "CFD1_YEAST", "id": "P40558-1", "name": "Cytosolic Fe-S cluster assembly factor CFD1", "aln": "MEEQEIG-VPAASLAGIKHIILILSGKGGVGKSSVTTQTALTLCSMGFKVGVLDIDLTGPSLPRMFGLENESIYQGPEGWQPVKVETNSTGSLSVISLGFLLGDRGNSVIWRGPKKTSMIKQFISDVAWGELDYLLIDTPPGTSDEHISIAEELRYSKPDGGIVVTTPQSVATADVKKEINFCKKVDLKILGIIENMSGFVCPHCAECTNIFSSGGGKRLSEQFSVPYLGNVPIDPKFVEMIENQVSSKKTLVEMYRESSLCPIFEEIMKKLRKQDTTTPVVDKHEQPQIESPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::::::**********:::*: :*:: * ***:**:** ***:* :: :.* ** ** : ::::*:.*** . :.*:****** :* **::** *.:** *::**********:: * *: *.::***** *: **::*:.**:*..:.::*::******.****:.*:.:** ..* *: ..**.:*:*. . .:: *. : * . : : ", "identical_positions": 97, "similar_positions": 83, "identity": "32.99%" }, { "cls_id": "homologset.agr.SGD:S000001266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62896-1", "uniprot_id": "BET1_RAT", "id": "Q62896-1", "name": "BET1 homolog", "aln": "--------------------------MRRAGLGDGAPPGGYGNYGYANSGYNACEEENDRLTESLRSKVTAIKSLSIEIGHEVKNQNKLLAEMDSQFDSTTGFLGKTMGRLKILSRGSQ--TKLLCYMMLFSLFVFFVIYWIIKLR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35623-1", "uniprot_id": "BET1_MOUSE", "id": "O35623-1", "name": "BET1 homolog", "aln": "--------------------------MRRAGLGDGAPPGSYGNYGYANTGYNACEEENDRLTESLRSKVTAIKSLSIEIGHEVKNQNKLLAEMDSQFDSTTGFLGKTMGRLKILSRGSQ--TKLLCYMMLFSLFVFFVIYWIIKLR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15155-1", "uniprot_id": "BET1_HUMAN", "id": "O15155-1", "name": "BET1 homolog", "aln": "--------------------------MRRAGLGEGVPPGNYGNYGYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLGKTMGKLKILSRGSQ--TKLLCYMMLFSLFVFFIIYWIIKLR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQT6-1", "uniprot_id": "Q6IQT6_DANRE", "id": "Q6IQT6-1", "name": "BET1 homolog", "aln": "--------------------------MRRAGLGEGGPQGNY-----VASGYSVYEEENEHLQEGLRDKVHALKHLSIDIGNEVKIHNKMLGEMDSDFDSTGGLLGATMGRLKLLSRGSQ--TKVYCYMLLFALFVFLVLYWVIKLR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35153-1", "uniprot_id": "BET1L_MOUSE", "id": "O35153-1", "name": "BET1-like protein", "aln": "--------------------------MADWTRAQS-----------SGAVEDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLCGMAVVLIVAFFILSYLLSRTRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35152-1", "uniprot_id": "BET1L_RAT", "id": "O35152-1", "name": "BET1-like protein", "aln": "--------------------------MADWTRAQS-----------SGAVEEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLCGMAVVLIVAFFILSYLFSRTRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYM9-1", "uniprot_id": "BET1L_HUMAN", "id": "Q9NYM9-1", "name": "BET1-like protein", "aln": "--------------------------MADWARAQS-----------PGAVEEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLSRART", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVX6-1", "uniprot_id": "Q9VVX6_DROME", "id": "Q9VVX6-1", "name": "BET1 homolog", "aln": "--------------------------MRRNNYPYQPLNQHPS--GPHPASHDALEAENEQAAEELKQKIGALKSLTIDIGNEVRYQDKLLRGIDDDMDRTSGFLGNAMTRVVRLAKQGGG-ARQMCYMFLFILVVFLILWITLKFK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22804-1", "uniprot_id": "BET1_YEAST", "id": "P22804-1", "name": "Protein transport protein BET1", "aln": "MSSRFAGGNAYQRDTGRTQLFGPADGSNSLDDNVSSALGSTDKLDYSQSTLASLESQSEEQMGAMGQRIKALKSLSLKMGDEIRGSNQTIDQLGDTFHNTSVKLKRTFGNMMEMARRSG--ISIKTWLIIFFMVGVLFFWVWIT----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :... : .:: :* *::.:. : . :: : :.. : * :. .. ::: . : : :. .:.: :. ", "identical_positions": 3, "similar_positions": 43, "identity": "2.03%" }, { "cls_id": "homologset.agr.SGD:S000001267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W90-1", "uniprot_id": "TXND5_MOUSE", "id": "Q91W90-1", "name": "Thioredoxin domain-containing protein 5", "aln": "-------------------------------------------------------------MPPRPGRLLQPLAGLPALATLLLLLG-----ARKGARAQEVEADSG---------VEQDPHAKHLYTADMFTHGIQS-------------------------------------AAHFVMFFAPWCG----------HCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLKFFKPGQE-----AVKYQGPRDFETLENWMLQTLNEEPATPEPEAEPPRAPELKQG-LYELSANNFELHVSQGN------HFIKFFAPWCG---------------------HCKALAPTWEQLALGLEH--SETVK--IGKVDCTQHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQL-QGSE--AAPETVEP--SEAPVMAAEPTGDKGTVLALT-EKSFEDTIAQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERN--VCSKYSVRGYP--------------------------------------TLLLFRGGEKVGEHNGGRDLDSLHSFVLR----------QAKDEL---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M279-1", "uniprot_id": "A0ABK0M279_RAT", "id": "A0ABK0M279-1", "name": "Thioredoxin domain-containing protein 5", "aln": "----------------------------------------------MGDPRPRRELASPAAMPPRPGRLFQPLAGLPALATLLLLLG-----ARKGARAQEVEADSG---------VEQDPHAKHLYTADMFTHGIQS-------------------------------------AAHFVMFFAPWCG----------HCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTANSDVCSAQGVRGYPTLKFFKPGQE-----AVKYQGPRDFETLENWMLQTLNEEPATPEPEAEPPRAPELKQG-LYELSANNFELHVSQGN------HFIKFFAPWCG---------------------HCKALAPTWEQLALGLEH--SETVK--IGKVDCTQHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQL-QGSE--AAPETVEP--SEAPVLAAEPPGDKGTVLALT-EKSFEDTIAQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLADVTIAEVDCTAERG--VCSKYSVRGYP--------------------------------------TLLLFRGGEKVGEHNGGRDLDSLHSFVLR----------QAKDEL---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBS9-1", "uniprot_id": "TXND5_HUMAN", "id": "Q8NBS9-1", "name": "Thioredoxin domain-containing protein 5", "aln": "-------------------------------------------------------------MPARPGRLLPLLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQS-------------------------------------AAHFVMFFAPWCG----------HCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQE-----AVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQG-LYELSASNFELHVAQGD------HFIKFFAPWCG---------------------HCKALAPTWEQLALGLEH--SETVK--IGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQL-QRTET-GATETVTP--SEAPVLAAEPEADKGTVLALT-ENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERN--ICSKYSVRGYP--------------------------------------TLLLFRGGKKVSEHSGGRDLDSLHRFVLS----------QAKDEL---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYV3-1", "uniprot_id": "TXND5_DROME", "id": "Q9VYV3-1", "name": "Thioredoxin domain-containing protein 5 homolog", "aln": "-------------------------------------------------------------MLTRS---ILSVAVCGLLLSPLLPIT----------RASQEEDTGK-----------QDKQFTVELDPETFDTAIAG-------------------------------------GNVFVKFFAPWCG----------HCKRIQPLWEQLAEIMN-VDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEE----SVKFKGTRDLPAITDFINKELSAPAEADLGEVKREQVENLNIGKVVDLTEDTFAKHVSTGN------HFVKFFAPWCS---------------------HCQRLAPTWEDLAKELIK--EPTVT--ISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVGVPLEK-TAGEAGDEKVVIEEVAGEEDAAKKLTPQQLTGEDEFDQAIAEGVAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYP--------------------------------------TLFLYKNGQRQNEYEGSRSLPELQAYLKKF---------LGHDEL---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q921X9-1", "uniprot_id": "PDIA5_MOUSE", "id": "Q921X9-1", "name": "Protein disulfide-isomerase A5", "aln": "---MARAWG--LLLAIGVVLPTWLSSTKVSSLIERISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTVCWVDCGDAESRKLCKKMKVDLSPKD--KKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLLKREEKPLLMMFYAPWCS----------MCKRIMPHFQKAATQVR--GHIVLAGMNVYPSEFENIKEEYNVRGYPTICYFEKGRFL----FPYENYGSTAEDIVEWLKNPLPPQPQVPETPWADE------GGSVYHLTDEDFDQFVKEHSS-----VLVMFHAPWCG---------------------HCKKMKPEFESAAEVLHG--DAESSGVLAAVDATVNEALAGRFHISAFPTLKYFKNG----EQQAVPALRTKKKFIEWMQ--------NPEAPPP-------PEPTWEEQQTSVLHLVGDNFRDTLKKKKHTLVMFYAPWCPHCKKVIPHFTATAD-AFKEDRKIACAAVDCVKDKNQDLCQQEAVKAYP--------------------------------------TFHYYHYGKLVEKYESDRTELGFTSFIRTLREGDLKRLEKRREEL---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0H9-1", "uniprot_id": "PDIA5_RAT", "id": "Q5I0H9-1", "name": "Protein disulfide-isomerase A5", "aln": "---MARAWG--LLLAIGVILPTWLSSTKVSSLIERISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKD--KKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLLKKEEKPLLMMFYAPWCS----------MCKRIMPHFQKAATQVR--GHTVLAGMNVYPPEFENIKEEYNVRGYPTICYFEKGRFL----FQYENYGSTAEDIVEWLKNPQPPQPQVPETPWADE------GGSVYHLTDEDFDQFVKEHSS-----VLVMFHAPWCG---------------------HCKKMKPEFESAAEVLHG--DAESSGVLAAVDATINEALAERFHISAFPTLKYFKNG----EQQAVPALRTKKKFIEWMQ--------NPEAPPP-------PEPTWEEQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATAD-AFKDDRKIACAAVDCVKDKNQDLCQQESVKAYP--------------------------------------TFHYYHYGKLVEKYESDRTELGFTSFIRTLREGDLKRLEKRREDL---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14554-1", "uniprot_id": "PDIA5_HUMAN", "id": "Q14554-1", "name": "Protein disulfide-isomerase A5", "aln": "---MARAGPAWLLLAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKD--KKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCS----------MCKRMMPHFQKAATQLR--GHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFL----FQYDNYGSTAEDIVEWLKNPQPPQPQVPETPWADE------GGSVYHLTDEDFDQFVKEHSS-----VLVMFHAPWCG---------------------HCKKMKPEFEKAAEALHG--EADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNG----EKYAVPVLRTKKKFLEWMQ--------NPEAPPP-------PEPTWEEQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATAD-AFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYP--------------------------------------TFHYYHYGKFAEKYDSDRTELGFTNYIRALREGDHERLGKKKEEL---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ17-1", "uniprot_id": "Q9VQ17_DROME", "id": "Q9VQ17-1", "name": "Thioredoxin domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTFRCIYFLFSLLIWSAQSD----KSLSKQSGNVTTITNLSVKARSADQCTP--------------GTILKLRVDNFFETTEDGT------FFVKFYEPNCM---------------------GCHDFETTWTDMAKSFKS--KENIC--FAELNCKFAKTICNDYELRYEPNLIWLENGEEVQQYDGDLTSPGIKIFVWEMI----------------------------RRNETNKSAAKRPYFHTKP------IILFG-WFLYAGDVISYFA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40557-1", "uniprot_id": "EPS1_YEAST", "id": "P40557-1", "name": "ER-retained PMA1-suppressing protein 1", "aln": "MKMNLKRLVVTFFSCITFLLKFTIAAAEPPEGFPEPLNPTNFKEELSKGLHIIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIKSFTETPRTKESLIAFARRESMDPNNLDTDLDSAKSESQYLEGFDFLELIAGKATRPHLVSFWPTKDMKNSDDSLEFKNCDKCHEFQRTWKIISRQLAVDDINTGHVNCESNPTICEELGFGDLVKITNHRADREPKVALVLPNKTSNNLFDYPNGYSAKSDGYVDFARRTFTNSKFPNITEGELEKKANRDIDFLQERGRVTNNDIHLVFSYDPETVVIEDFDILEYLIEPLSKIPNIYLHQIDKNLINLSRNLFGRMYEKINYDASQTQKVFNKEYFTMNTVTQLPTFFMFKDGDPISYVFPGYSTTEMRNIDAIMDWVKKYSNPLVTEVDSSNLKKLISFQTKSYSDLAIQLISSTDHKHIKGSNKLIKNLLLASWEYEHIRMENNFEEINERRARKADGIKKIKEKKAPANKIVDKMREEIPHMDQKKLLLGYLDISKEKNFFRKYGITGEYKIGDVIIIDKSNNYYYNKDNFGNSLTSNNPQLLREAFVSLNIPSKALYSSKLKGRLINSPFHNVLSFLDIIHGNGMPGYLIVIVLFIAILKGPSIYRRYKVRKHYRAKRNAVGILGNMEKKKNQD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : . : :: . * : : . : : . : : *.: :.:* : . : . : . * : : ", "identical_positions": 5, "similar_positions": 30, "identity": "0.71%" }, { "cls_id": "homologset.agr.SGD:S000001268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMG8-1", "uniprot_id": "S2532_MOUSE", "id": "Q8BMG8-1", "name": "Solute carrier family 25 member 32", "aln": "------------------------------------------------------MTGQGQSAAGSAAWSAVFRHVRYEN-LVAGVSGGVLSNLALHPLDLVKIRFAVS--DGLEVRPKYKGILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEPLEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNKHINRLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTD----VITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLYDLR-------------EKKVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y115-1", "uniprot_id": "A0A8I5Y115_RAT", "id": "A0A8I5Y115-1", "name": "Solute carrier family 25 member 32", "aln": "------------------------------------------------------MTSQGQSAAGSAAWSAVFRHVRYEN-LVAGVSGGVLSNLALHPLDLVKIRFAVS--DGLEVRPKYKGILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEALEYLISAAEAGAMTLCITNPLWVTKTRLMLQYGGVVNPSQRQYKGMIDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEVLKLKYNKHINKLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTD----VITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENCMCLKQQQTPLCLKHKARKSPAEQHSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2D1-1", "uniprot_id": "S2532_HUMAN", "id": "Q9H2D1-1", "name": "Solute carrier family 25 member 32", "aln": "------------------------------------------------------MTGQGQSASGSSAWSTVFRHVRYEN-LIAGVSGGVLSNLALHPLDLVKIRFAVS--DGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVID----VITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLR-------------EKRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40556-1", "uniprot_id": "YIA6_YEAST", "id": "P40556-1", "name": "Mitochondrial nicotinamide adenine dinucleotide transporter 1", "aln": "MTQTDNPVPNCGLLPEQQYCSADHEEPLLLHEEQLIFPDHSSQLSSADIIEPIKMNSSTESIIGTTLRKKWVPLSSTQITALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYKGLVPIVLGYFPTWMIYFSVYEFSKKFFHG-IFPQFDFVAQSCAAITAGAASTTLTNPIWVVKTRLMLQSN--LGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLKVRFHCYSRENNTNSINLQRLIMASSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRTIPASAITLVSFEYFRNRLENIS-------------TMVI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *... :* *:: . . : ::*. .*.**.:*: ***:.* *: .. : .* *.**: *:** : :* ****:*:.* : * :* :** .*: *.: ::: :* *** : :***:**.******* . . :*** :*:: *:: **.:.** *:**.*:* * *::* ** **:::: : .. .:. . * .:::**::* *.***::::*:*:* : ..: :*. *: :**: ***.*::.**:*. **..**:* :* : ", "identical_positions": 98, "similar_positions": 107, "identity": "25.13%" }, { "cls_id": "homologset.agr.SGD:S000001269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2X8-1", "uniprot_id": "A0ABK0M2X8_RAT", "id": "A0ABK0M2X8-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSSEEVRHRAESSEARAAAVSDIQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHAR--DKEKQARDMAEAREEAMNRRLA-SDSPALP--KAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SLQNVGSVVQHSEGKPLNVMVIRRGEKHQLRLTPTR-WAGKGLLGCNITPLQR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR00-1", "uniprot_id": "PSMD9_MOUSE", "id": "Q9CR00-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSGEDVPHRAESSEARAAAVSDIQDLMRRKEEIEAEIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHAR--DKEKQARDMAEAREEAMNRRLA-SNSPVLP--QAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SVQNVGTVVQHSEGKPLNVTVIRRGEKHQLRLIPTR-WAGKGLLGCNIIPLQR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00233-1", "uniprot_id": "PSMD9_HUMAN", "id": "O00233-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHAR--DKEKQARDMAEAHKEAMSRKLGQSESQGPP--RAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTR-WAGKGLLGCNIIPLQR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFS8-1", "uniprot_id": "PSMD9_DROME", "id": "Q9VFS8-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------------------MAAGTTTKERLERLINAKKQLEAQINRNGQILAANDNVGMSGPLVDAEGFPRNDIDVYQVRLARQTIICLQNDHKELMNQIQTLLNQYHSEIATTDPELVNRASALDLDSDRSPGGANITDLAPARAIVVVNLVSPDSPAERAGLCAGDAILRFGSINSGNFKGDLAQIGELVRNMQSQNVQLKVKRGEQQLDLILVPKT-WSGRGLLGCNIVLPPEAMDH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40555-1", "uniprot_id": "PSMD9_YEAST", "id": "P40555-1", "name": "Probable 26S proteasome regulatory subunit p27", "aln": "MEEEELSKLLANVKIDPSLTSRISQIDSFKLSELMVLKTDIETQLEAYFSVLE-QQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQHFDN--------MNVKSNQDARRN-----NDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISIGNVHAANHS-KLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: * ::*:::: .:* :..:**. .** :*:** *:*: ** *:.: *:** : :::: . *:* . . : . . . : .:. :. : *.**:. *.: ..* :: :*.::: *.. .: :: :* : :.: : : : * : . * *. * *:*****.* ", "identical_positions": 40, "similar_positions": 78, "identity": "16.6%" }, { "cls_id": "homologset.agr.SGD:S000001270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BTM9-1", "uniprot_id": "URM1_HUMAN", "id": "Q9BTM9-1", "name": "Ubiquitin-related modifier 1", "aln": "MAAP-LSVEVEFGGGAELLFDGIKKHRVTLPGQEEPWDIRNLLIWIKKNLLKERP--ELFIQGDSVRPGILVLINDADWELLGELDYQLQDQDSVLFISTLHGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D2P4-1", "uniprot_id": "URM1_MOUSE", "id": "Q9D2P4-1", "name": "Ubiquitin-related modifier 1", "aln": "MAAP-LCVKVEFGGGAELLFDGVKKHQVALPGQEEPWDIRNLLVWIKKNLLKERP--ELFIQGDSVRPGILVLINDADWELLGELDYQLQDQDSILFISTLHGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F2Z4T6-1", "uniprot_id": "F2Z4T6_DANRE", "id": "F2Z4T6-1", "name": "Ubiquitin-related modifier 1", "aln": "MAAP-LGLHLEFGGGAELLFDGVKNHHVTLPDQSNPWDMKQLLAWIRGNMLKERP--ELFMQGDTVRPGILVLINDADWELMGELDYQLQDKDNVVFISTLHGG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KU86-1", "uniprot_id": "URM1_DROME", "id": "Q7KU86-1", "name": "Ubiquitin-related modifier 1 homolog", "aln": "MGTPELKIILEFSAGAELLFGNIKRRELNLDGKQK-WTIANLLKWMHANILTERP--ELFLQGDTVRPGILVLINDTDWELLGELDYELQPNDNVLFISTLHGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40554-1", "uniprot_id": "URM1_YEAST", "id": "P40554-1", "name": "Ubiquitin-related modifier 1", "aln": "----MVNVKVEFLGGLDAIFGKQRVHKIKMD-KEDPVTVGDLIDHIVSTMINNPNDVSIFIEDDSIRPGIITLINDTDWELEGEKDYILEDGDIISFTSTLHGG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :** .* : :*. : :.: : :.. : :*: : .::.: .:*::.*::****:.****:**** ** ** *: * : * ******", "identical_positions": 32, "similar_positions": 36, "identity": "30.77%" }, { "cls_id": "homologset.agr.SGD:S000001271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZW4-1", "uniprot_id": "ACSL3_MOUSE", "id": "Q9CZW4-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNQIKAKPV----------------------SSKPDSAYRSIN-SVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKP--KANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP-----------------PTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMAR-RIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKG---TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63151-1", "uniprot_id": "ACSL3_RAT", "id": "Q63151-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTIHPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNHIKAKPV----------------------SSKPDSAYRSVN-SMDGLASVLYPGCDTLDKVFMYAKNKFKDKRLLGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKP--KANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP-----------------PTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMAR-RIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFNG---TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95573-1", "uniprot_id": "ACSL3_HUMAN", "id": "O95573-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFS----ESRQEKSNRIKAKPV----------------------NSKPDSAYRSVN-SLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKP--KTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP-----------------PTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAE-RIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKG---TWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXZ5-1", "uniprot_id": "A0AB32TXZ5_DANRE", "id": "A0AB32TXZ5-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MKLKEDMSPLLLQVFRSVVWVYSVITFLPWYLLSGASGN--QARAKRVKARAI----------------------NGNPAGPYRAVN-SQLKLASLLHEGVDTLDKVFEYAVVHFPERDCLGTRELLSEEDEIQPNGKVFKKVILGDYNWLSYQDTFHLAQRFGSGLAALGQKP--LCNIAIFCETRAEWVIAAQACFMYNFPLVTLYSTLGGSAIAHGLNETEVTHIVTSKDLLQSRLKAILLEVPRLKHIIVVDTKP-----------------TSWPDLPRGIMVHNMAAVQELGSKPENIMVSRRQPVPSDIAVIMYTSGSTGIPKGVMISHSNIIAGITGMAE-RIPNLDENDTYIGYLPLAHVLELSAELVCVSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMTKVEEMSSVQKTLFVLAYNYKMEQISKGYTTPLCDRLVFRKVRSLLGGNTRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISEMSDYSTGRVGAPLVCSEIMLKDWEEGGYFGTDKPNPRGEILIGGPNVTMGYYKNEQKNREDFFEDKNGQRWFCTGDIGEFHPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAVLKNCPLIDNICAYANSDESYVIGFVVPNQKQLTALAGQKGIRG---SWEEICNHAEMEKEVLRIITDAAISGKLERFEIPKKICLSAEPWTPETGLVTDAFKLKRKELKTHYQDDIERMYGGK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LVA8-1", "uniprot_id": "Q1LVA8_DANRE", "id": "Q1LVA8-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MRLTQDLSPAVVLVFRLVVWLYSLISYLPYLLLRSPESQSLSECSRRLKARSV----------------------SGDPAGPYRDVA-ALKGLEMCLHPGINTLDQVFQSSVSHFPNSDCLGTRELLSEEDETQEDGKVFKKVILGEYRWMSYEQVFKEVNAFGSGLAALGQKP--MKNIAIFCETRAEWIIAAQACFMYNFPLVTLYSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVDDKL-----------------STSSEYPRGISIHSMASVKELGARPENASKPKNPPCSSDVAVIMYTSGSTGVPKGVMISHSNIISGITGMTH-RIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYSSPQTLSDQSTKIKKGSRGDISVLRPTLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKMEQLAMGYSTPLCDKLVFRKVRALLGGRLRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISHLWDYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKNTHKTSEDFFVDKKGQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLVDNICAYANSDESYVIGFVVPNQKQLLALAERKRVRG---LWEELCNNPVIEEAVLTVLTEAALTAQLERFEIPRKIRLSVEPWTPDTGLVTDSFKLKRKELKTHYQNDIERMYGAK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QUJ7-1", "uniprot_id": "ACSL4_MOUSE", "id": "Q9QUJ7-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKT-----------------INRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG---SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35547-1", "uniprot_id": "ACSL4_RAT", "id": "O35547-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIVLLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVDNKT-----------------INRAEYPEGLEIHSMQSVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG---SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60488-1", "uniprot_id": "ACSL4_HUMAN", "id": "O60488-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKA-----------------INKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEG---TWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFE4-1", "uniprot_id": "A0A0B4KFE4_DROME", "id": "A0A0B4KFE4-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-------------MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKP--WKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKP--RENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLP-KFKTLLDKCPLVKTIIYIEDQLQK---------------TETTGFKEGVKILPFNQVVKTGQDSKFEHVP---PKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVD-MVP-IYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFE-EDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDK--SFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39002-1", "uniprot_id": "LCF3_YEAST", "id": "P39002-1", "name": "Long-chain-fatty-acid--CoA ligase 3", "aln": "-----------------------------------MSEQHSVAVGKAANEHETAPRRNVRVKKR---------------------------PLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTIVRKVDGKDKSIEKTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDPNDRRQNGKLYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSK-DEVKLHPPEPKDLACIMYTSGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGYGSVKTLTNTSTRN---CKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYSMKEKSVP---CTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLCP-MIIGYGLTETVANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNN---QGELLLKGAPVCSEYYKNPIETAVSFTY----DGWFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ..::.: * :. : . . : . :.: : : : :. *. .: : :* ** :* ** .: **..* :*: *: : :** * *** .: * : *:* : :.*. :** : : . .. : : * * .. * .*:* :****** . ****:: * * :: : * . : * :.:*****::** * .. . :**.: ** : *:: .:** ::** * .*. : : : * : ::.. . . :.:* *. * : : : : . ::*::* **. : :: **:.:* ::. :. :* : ******: . . : . . * .* : * : : .* : :**::: * : *:* :. .: : *: **** * .* *:****:*:*** ***::* *:*: :. :.***.:.. . :.:**** * :* . : :. :: : * * *: : : : *:*: *:** : ****::: :::*:* ", "identical_positions": 135, "similar_positions": 191, "identity": "17.51%" }, { "cls_id": "homologset.agr.SGD:S000001277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5Z0-1", "uniprot_id": "BACE2_HUMAN", "id": "Q9Y5Z0-1", "name": "Beta-secretase 2", "aln": "MGALARALLLPLLAQWLLRAAPELAPAPFT--LPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVT-----------VKYTQGSWTGFVGEDLVTIP--KGFN---TSFLVNIATIFESE--------NFFLPG-IKWNGILGLAYATLAKPSSSLETF--FDSLVTQANIPNVFSMQMCGAGLPVAG-----SGTNGGSLVLGGIEPSLYKG-----DIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTN------SETPW--SYFPKISIYLRDENSSRSFRITILP------QLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEG----------FYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMS---VCGAILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12630-1", "uniprot_id": "BAR1_YEAST", "id": "P12630-1", "name": "Barrierpepsin", "aln": "MSAINHLCLKLILASFAIINTITALTNDGTGHLEFLLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDSGTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNASEVSKKLVNIQTDGSISGAKIATAEPWSTNEPFTVTSDIYSSTGCKSRPFLQSSTASSLIAETNVQSRNCSTKMPGTRSTTVLSKPTQNSAMHQSTGAVTQTSNETKLELSSTMANSGSVSLPTSNSIDKEFEHSKSQTTSDPSVAEHSTFNQTFVHETKYRPTHKTVITETVTKYSTVLINVCKPTY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*: : * :**.: : : . * * : : : *.* . ***:: : : . . :. . *. :. . ... *: . :.:. : **.: . : ** .* ..:: :: ..:. .**: . :*.:* .: **:: ..: *:. *::** .:** . . .* : :. :* *..* ** .:. * .: * .::* : * * . : *. ** . .** :. * : :: .: : * *: . ::: . .* * . ::*: *:. . ** :. :.* * :.: :. : ::: * * ..* : :: :.* . :*: : : . : :. . :. * *.::.:*: :.* . .::.:. :. .: *. * : :::. . : : .* .:*:.. : : . * *. : .: :* ::. .*.*.. *::: : * ", "identical_positions": 78, "similar_positions": 201, "identity": "13.29%" }, { "cls_id": "homologset.agr.SGD:S000001279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M943-1", "uniprot_id": "F1M943_RAT", "id": "F1M943-1", "name": "Armadillo repeat-containing protein 8", "aln": "-----------------------------------MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQG-VIDMKNAVIGNNKQKANLIVLGAVP-----RLLYLLQQEASSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTS-----PVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVS----MTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVR------------------------------LAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQN-----------------APDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQS-----------------------ENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDMNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVT------------------------LILEGEHSMEVKEQTLCILANIADG-TTAKELIMTNDDILQKIKYYMGHS---------HVKLQLAAMFCISNLIWN------------------------------------------------------------------------EEEG---------------------SQERQDKLRDMGIVDILHKLSQSTDSNLCDKAKTALQQYLA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBR3-1", "uniprot_id": "ARMC8_MOUSE", "id": "Q9DBR3-1", "name": "Armadillo repeat-containing protein 8", "aln": "-----------------------------------MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQG-VIDMKNAVIGNNKQKANLIVLGAVP-----RLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTS-----PVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVS----MTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETETMMDRIVTGSSESSVKVR------------------------------LAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQN-----------------APDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQS-----------------------ENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDMNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVT------------------------LILEGEHSIEVKEQTLCILANIADG-TTAKELIMTNDDILQKIKYYMGHS---------HVKLQLAAMFCISNLTWN------------------------------------------------------------------------EEEG---------------------SQERQDKLRDMGIVDILHKLSQSADSNLCDKAKTALQQYLA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUR7-1", "uniprot_id": "ARMC8_HUMAN", "id": "Q8IUR7-1", "name": "Armadillo repeat-containing protein 8", "aln": "-----------------------------------MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQG-VIDMKNAVIGNNKQKANLIVLGAVP-----RLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTS-----PVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVS----MTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVR------------------------------LAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQN-----------------APDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQS-----------------------ENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVT------------------------LILEGEHNIEVKEQTLCILANIADG-TTAKDLIMTNDDILQKIKYYMGHS---------HVKLQLAAMFCISNLIWN------------------------------------------------------------------------EEEG---------------------SQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05AL1-1", "uniprot_id": "ARMC8_DANRE", "id": "Q05AL1-1", "name": "Armadillo repeat-containing protein 8", "aln": "-----------------------------------MACLLEAPLRISVLSEVTATSRHYVDRLFDPDPQNVLQG-VIDMKNAVIGNNKQKANLIVLGAVP-----RLLYLLQQSSSTLELRTECAVVLGSLSMGTENNIKSLVDCHIIPALLQGLLCSDLIFIEACLRCLRTVFIS-----PVTPVQLLYTDPTVIPHLMSLLSRSQHTQEYITQIFAHCCKTPEHQTVLFNHGAIQNIAPLLISPSYKVRMQALKCFSVLAYENAQVS----MTLVNVLVDGEQLSQVFVRMMQRDKPIEMQLTAAKCLTYMCRAGAIRTEDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLMEPDIELQRIASVTDHLVSMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGSNDEDIRKKITETENMMDRIVSGLSESSIKVR------------------------------LAAVRCLHSLSRSVQQLRTSFHDHAVWKPLMKLLQN-----------------APDEVLVMASSTLCNLLLEFSPSKEPILESGVIELLCSLTQS-----------------------DSSALRVNGIWALMNMAFQADQKVKVEIVRALGTEQLFRLLSDPDTNVLMKTLGLLRNLLSTRPHIDQIMSSHGKQIMQAVT------------------------LILEGEHSIEVKEQTLCILANIADG-NTAKELIMTDDDMLQKIKYYMGHS---------NVKLQLAATFCISNLIWN------------------------------------------------------------------------EEDG---------------------SQERQDKLREMGFVDILHKLTQASDPDLCDRAKTAMQQYLA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40547-1", "uniprot_id": "VID28_YEAST", "id": "P40547-1", "name": "GID complex subunit 5", "aln": "MTVAYSLENLKKISNSLVGDQLAKVDYFLAPKCQIFQCLLSIEQSDGVELKNAKLDLLYTLLHLEPQQRDIVGTYYFDIVSAIYKSMSLASSFTKNNSSTNYKYIKLLNLCAGVYPNCGFPDLQYLQNGFIQLVNHKFLRSKCKIDEVVTIIELLKLFLLVDEKNCSDFNKSKFMEEEREVTETSHYQDFKMAESLEHIIVKISSKYLDQISLKYIVRLKVSRPASPSSVKNDPFDNKGVDCTRAIPKKINISNMYDSSLLSLALLLYLRYHYMIPGDRKLRNDATFKMFVLGLLKSNDVNIRCVALKFLLQPYFTEDKKWEDTRTLEKILPYLVKSFN----YDPLPWWFDPFDMLDSLIVLYNEITPMNNPVLTTLAHTNVIFCILSRFAQCLSLPQHNEATLKTTTKFIKICASFAASDEKYRLLLLNDTLLLNHLEYGLESHITLIQDFISLKDEIKETTTESHSMCLPPIYDHDFVAAWLLLLKSFSRSVSALRTTLKRNKIAQLLLQILSKTYTLTKECYFAGQDFMKPEIMIMGITLGSICNFVVEFSNLQSFMLRNGIIDIIEKMLTDPLFNSKKAWDDNEDERRIALQGIPVHEVKANSLWVLRHLMYNCQNEEKFQLLAKIPMNLILDFINDPCWAVQAQCFQLLRNLTCNSRKIVNILLEKFKDVEYKIDPQTGNKISIGSTYLFEFLAKKMRLLNPLDTQQKKAMEGILYIIVNLAAVNENKKQLVIEQDEILNIMSEILVETTTDSSSNGNDSNLKLACLWVLNNLLWNSSVSHYTQYAIENGLEPGHSPSDSENPQSTVTIGYNESVAGGYSRGKYYDEPDGDDSSSNANDDEDDDNDEGDDEGDEFVRTPAAKGSTSNVQVTRATVERCRKLVEVGLYDLVRKNITDESLSVREKARTLLYHMDLLLKVK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***. .* : : . *. ::*: :.:: :*: .*: . . :.: .: . :** * .. : : * : : ..: ::* . . : :::: * * : * :: * . . *. :. . : *:: :* . * : *. . * : : *. :: . : . *:.:. : *:*: * : : .: ::** : :.: :::: .: * * : : :*. : * ** **: . : :.: * . : :.*:.:.: ::: **. . :* ::: * :. : : : :*: **:.:.**. * : : ::::: * .. :: * : *:*:****. ***::: : : : *:::*.: . :: :: . :**:::*** :. :*..* :::: : . ::.*.:*.* :: ::.::: * ::: : : :: ::.*. * : : ***** .. :* :*: : *:: : * . :. :. * * *:.*:* . *:*:: :*::*: :. : .: . :*:**. : :.** ** :::* : ** ** ::*: *:::* . .: ::*: : : ", "identical_positions": 110, "similar_positions": 263, "identity": "11.89%" }, { "cls_id": "homologset.agr.SGD:S000001280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62918-1", "uniprot_id": "RL8_MOUSE", "id": "P62918-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62919-1", "uniprot_id": "RL8_RAT", "id": "P62919-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62917-1", "uniprot_id": "RL8_HUMAN", "id": "P62917-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A6W6-1", "uniprot_id": "D4A6W6_RAT", "id": "D4A6W6-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRDQRKGAGSVFRAHLKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRSAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVQGVAMNPVEHPFGGDNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P0V6-1", "uniprot_id": "RL8_DANRE", "id": "Q6P0V6-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFKAHVKHRKGAAKLRHIDFAERHGYIKGIVKDIIHDPGRGAPLAKVMFRDPYRFKKRTELFIAAEGIHTGQFIYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKSRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQDKEN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3G1-1", "uniprot_id": "RL8_DROME", "id": "Q9V3G1-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRAQRKGAGSVFKAHVKKRKGAAKLRSLDFAERSGYIRGVVKDIIHDPGRGAPLAVVHFRDPYRYKIRKELFIAPEGMHTGQFVYCGRKATLQIGNVMPLSQMPEGTIICNLEEKTGDRGRLARTSGNYATVIAHNQDTKKTRVKLPSGAKKVVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGKASTVKRGTSAGRKVGLIAARRTGRIRGGKGDSKDK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX46-1", "uniprot_id": "RL2B_YEAST", "id": "P0CX46-1", "name": "Large ribosomal subunit protein uL2B", "aln": "MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *******:* :* : *:***:** :*:*** ***:*:**:*:**.**.**** * *****::: * *:*** **:*****:*.*:** *::***:*:. :*****:. :***.**** ***:****. :*.** : :*:**:****:***:.* *.::*::*****:***:******:***: ***.**:.:*******:**.**.*******.**: *.: :*:*.********* :** : .. ", "identical_positions": 158, "similar_positions": 69, "identity": "61.48%" }, { "cls_id": "homologset.agr.SGD:S000001283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB90-1", "uniprot_id": "Q5EB90_RAT", "id": "Q5EB90-1", "name": "DNA-directed RNA polymerase II subunit RPB3", "aln": "MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVE-QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPK----PEEWPKSEYSELDEDESQ-APYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQS--------------------DVLTIN------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97760-1", "uniprot_id": "RPB3_MOUSE", "id": "P97760-1", "name": "DNA-directed RNA polymerase II subunit RPB3", "aln": "MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVE-QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPK----PEEWPKSEYSELDEDESQ-APYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQS--------------------DVLTIN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19387-1", "uniprot_id": "RPB3_HUMAN", "id": "P19387-1", "name": "DNA-directed RNA polymerase II subunit RPB3", "aln": "MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVE-QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPK----PEEWPKSEYSELDEDESQ-APYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQS--------------------DVLTIN------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97183-1", "uniprot_id": "O97183_DROME", "id": "O97183-1", "name": "DNA-directed RNA polymerase II subunit RPB3", "aln": "MPYANQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLAHRIGLIPLISDDVVERLQYTRDCICLDFCPECSVEFTLDVKCSEEQTRHVTTADLKSSNAKVLPVTSRNQGEEDNEYGESNDEILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVCFEYDPDNSMRHTLYPK----PDEWPKSEHTELEDDQYE-APYNWEAKPNKFFFNVESAGALKPENIVVMGVQVLKNKLSNLQTQLSHESQN--------------------DALAV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16370-1", "uniprot_id": "RPB3_YEAST", "id": "P16370-1", "name": "DNA-directed RNA polymerase II subunit RPB3", "aln": "MSEEG-PQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMD-IEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSN----LMGRNIGHPIIQDKE-GNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * *:* * :.:**.*::.:.:*::***:***:*** * :*** *::::*::** ***:***:***** * * :::*:*:*** * :.* :*** :**:. ..:.* :* : ** . : .** .. : * : :** ********:* . ****:.******.*:*.: ***** * ::** * ..***:*: * :: : *:: :.:.: *: **** *:: : :*: .:. *::*::.: *:: *. *.: ", "identical_positions": 108, "similar_positions": 95, "identity": "33.23%" }, { "cls_id": "homologset.agr.SGD:S000001284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35094-1", "uniprot_id": "TIM44_RAT", "id": "O35094-1", "name": "Mitochondrial import inner membrane translocase subunit TIM44", "aln": "-MAAAALR---------GGWCRCPRRCLGSGIQFLSSHNLPRGGSSYQISRPGGELTLTKS--YSS-GSRKGFLSGLLDNIKQELAQNKEMKESIKKFRDEAKKLEESDALQEARRKYKTIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKGGEKLGKTAAFKAISQGVESVKKEIDESVLGHTGTYRRPERLRKRTEFAGAKFKESKVFE-ANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMK-MKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDRFLHQCETDIIPNILEAMISGELDILKDWCYEATYNQLAHSIQQAKALGLQFHSRILDISNVDLAMGKMME--QGPVLIVTFQAQLVMVIKNPK-GEVFDGDPDKVLRMLYVWALCRDQEELN--PYAAWRLLDISASSTEQIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35857-1", "uniprot_id": "TIM44_MOUSE", "id": "O35857-1", "name": "Mitochondrial import inner membrane translocase subunit TIM44", "aln": "-MAAAALR---------GGWCRCPRRCLGSGIQFLSSHNLPHG-SSYQISRPGRELTLTKS--YSS-GSRKGFLSGLLDNIKQELAKNKEMKESIKKFRDEAKKLEESDALQEARRKYKSIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKSGEKLGKTAAFKAISQGVESVKKELDESVLGQTGPYRRPERLRKRTEFAGAKFKESKVFE-ANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMK-MKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDHFLHQCETDIIPNILEAMISGELDILKDWCYEATYSQLAHPIQQAKALGFQFHSRILDISNVDLAMGKMME--QGPVLIVTFQAQVVMVIKNSK-GEVYDGDPDKVQRMLYVWALCRDQEELN--PYAAWRLLDISASSTEQIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43615-1", "uniprot_id": "TIM44_HUMAN", "id": "O43615-1", "name": "Mitochondrial import inner membrane translocase subunit TIM44", "aln": "-MAAAALR---------SGWCRCPRRCLGSGIQFLSSHNLPHG-STYQMRRPGGELPLSKS--YSS-GNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFE-PNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMK-MKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDNVDLAMGKMME--QGPVLIITFQAQLVMVVRNPK-GEVVEGDPDKVLRMLYVWALCRDQDELN--PYAAWRLLDISASSTEQIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDZ7-1", "uniprot_id": "Q9VDZ7_DROME", "id": "Q9VDZ7-1", "name": "Mitochondrial import inner membrane translocase subunit TIM44", "aln": "-MKATSCRPIPFINFRIVRYFYRPRRLNKYYDIYRIAALVRDRACLFTCQQASQNLQQQQPRFYSAPGRRAGFFSQFFDNMKAEMDKNKEIKDNIRKFREEAQKLEESDALKSARQKFNIVESEAQKSSSMLKEQLGAIKERVGDVLEDASKSHLAKKVTE---ELSKKARGVSDTISDTSGKLGQTSAFQAISNTTTTIKKEMDSASIENR-VYRAPAKLRKRVQLVMS--DSDRVVE-PNTEATGMELHKDSKFYESWENFKNNNTYVNKVLDWK-VKYDESENPVIRASRLLTDKVSDVMGGLFSKTELSETMTELVKIDPSFDQKDFLRDCETDIIPNILESIVRGDLEILKDWCFESTFNIIANPIKEAKKAGVYLDSKILDIENIELAMGKVME--QGPVLIITFQAQQIMCVRDQK-SQVVEGDPEKVMRVHYVWVLCRDRNELN--PKAAWRLMELSANSSEQFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01852-1", "uniprot_id": "TIM44_YEAST", "id": "Q01852-1", "name": "Mitochondrial import inner membrane translocase subunit TIM44", "aln": "MHRSTFIR----------TSGTSSRTLTARYRSQYTGLLVARVLFSTSTTRAQG-------------GNPRSPLQIFRDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQ----RGSTIVGKTLKKTGETMEHIATKAWESELG-------KNTRKAAAATAKKLDESFEPVRQTKIYKEVSEVID----DGESSRYGGFITKEQRRLKRERDLASGKRHRAVKSNEDAGTAVVATNIESKESFGKKVEDFKEKTVVGRSIQSLKNKLWDESENPLIVVMRKITNKV----GGFFAETESSRVYSQFKLMDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIFKEQDVYADGRILDIRGVEIVSAKLLAPQDIPVLVVGCRAQEINLYRKKKTGEIAAGDEANILMSSYAMVFTRDPEQIDDDETEGWKILEFVRGGSRQFT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .* . : :. * . :. : *..* * :.:*:::.*:.::: : :* **:. :.**. : : : * : : * : . .. :*.*. : : * :..:.. : :* :: :*: : :.: . *:* : * .. . . :.....: :. ::**::.. . . . * :***:* .* . * :*:** **:*::** *.. ::: :**:*.:. * :. . *:*::**: : *::.:**.* *:.:. * : * .. ..:**** .:::. .*:: : ***:: :** : :. * .:: ** :: *. .: ** :::: .*::::: ..:.*: ", "identical_positions": 74, "similar_positions": 167, "identity": "15.64%" }, { "cls_id": "homologset.agr.SGD:S000001285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q31125-1", "uniprot_id": "S39A7_MOUSE", "id": "Q31125-1", "name": "Zinc transporter SLC39A7", "aln": "--------MTMGLRAPHWVAVGLLTWAALGLLVAGHEGHGDLHKDVEEDFHG--HSHGHSHEDFHHGHSHGHSHEDFHHGHGHTHESIWHGHAHSHDHGHSREELHHGHSHGHSHDSLHHGGHGHAHREHSHGTSREAGAPGIKH-HLDTVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-------RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHAPEQP-----------GHGHSH-SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHG-HSHGHGDRHAHG-DSHTHGDRHECSSKEKPSTEEE-KEVGGLRKRRGGNTGPRDGPVKPQSPEEEKAGSDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLVTAIGALAGTACALLTEGGAV---DSDVAGGAGPGWVLPFTAGGFIYVATVSVLPELLR-EASPLQS------LLEVLGLLGGVAMMVLIAHLE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92504-1", "uniprot_id": "S39A7_HUMAN", "id": "Q92504-1", "name": "Zinc transporter SLC39A7", "aln": "--------MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHG--HSHRHSHEDFHHGHSHAH-------GHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDH-EHSHGGYGESGAPGIKQ-DLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-------RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQP-----------GHGHSH-SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHG-HSHGHGHAHSHTRGSHGHG-RQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAV---GSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLR-EASPLQS------LLEVLGLLGGVIMMVLIAHLE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUB8-1", "uniprot_id": "S39A7_DANRE", "id": "Q9PUB8-1", "name": "Zinc transporter Slc39a7", "aln": "--------MRVFSKSLLLIAVGILMSQQTLAHSHHHHGHGD------GGCHG--HSHGG--AKMHHGASKWS---------AEANLPHAEEEHHVHDHGHTHNHAHD-HGHAHSHGDIHDHGHAHKH-GHAHDHGAEKSKKVVEAGKRNMVELWMQAIGATLLISAAPFLILFLIPVQSNTDQH-------QNLLKVLLSFASGGLLGDAFLHLIPHALEPHSHHSQPHSEESHGQSHGEESHGHSHGAAHGHMMSVGLWVLGGIVAFLVVEKFVRLLKGGHS-HSHSH----------------SPSAPKSKDSDEED--DKKGQKKGEKDKVVSQQKPTK----KTVETSSDIKVSGYLNLAADFTHNFTDGLAIGASFLVGPAVGAVTTITILLHEVPHEIGDFAILVQSGCTKRKAMCLQLLTAVGALAGTACSLLAEG----------VGDAATAWILPFTAGGFVYIATVTVLPELLAGHSSFWQS------LLEILALLFGVGMMVLIAEYE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3A4-1", "uniprot_id": "CSUP_DROME", "id": "Q9V3A4-1", "name": "Protein catecholamines up", "aln": "MAKQVADYQCSKLQLYQKLALVVILGAVLFSLPALCAGQGNPSFKYSREANENFDPQKAPRAEHHHHHDHDH---------DHGHHHHGHDHDHDHDHGHDHGHHHHGHDHDHDHD------HGHHH--HGHDERHTKAKP-----DLDMSTIWLHSIGSTLLISAAPFVLLYIIPLD-NSEAM-------KPRLKVLLAFASGGLLGDAFLHLIPHATHPHSHGEHGHDHG---HDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEKLVRILKGGHGGHGHSHGAPKP-----------KPVPAKKKSSDKED--SGDGDKPAKPAKIKSKK--------PEAEPEGEVEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILIKSGCSRRKAMLLQLVTALGALAGTALALLGAGG----------GDGSAPWVLPFTAGGFIYIATVSVLPELLEESTKLKQS------LKEIFALLTGVALMIVIAKFE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2M1K6-1", "uniprot_id": "S39AD_RAT", "id": "Q2M1K6-1", "name": "Zinc transporter ZIP13", "aln": "--------MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDSKESESWGALLSGER------------------------------------------------------------------------------LDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQ---SEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQ-----------------SLQRQQQLGLWVIAGFLTFLALEKMFLNCKEEDPSQAPSKDPT--AAALN---------------GGHCL---------AQPAAEPGLR-----------AVVRNLKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKG--------VEETVVWTLPFTSGGFLYVALVNVLPDLLEEDDPWHLN-----PPLPTGTPCSRCCCSAPVSW----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZH0-1", "uniprot_id": "S39AD_MOUSE", "id": "Q8BZH0-1", "name": "Zinc transporter ZIP13", "aln": "--------MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDNKESESWGALLSGER------------------------------------------------------------------------------LDTWICSLLGSLMVGLSGVFPLLVIPLEMGTLLQ---SEAGAWRLRQLLSFALGGLLGNVFLHLLPEAWAYTCNITPGGEGQ-----------------SLQRQQQLGLWVIAGFLTFLALEKMFLNSKE-DPSQAPSKDPT--AAALN---------------GGHCL---------AQPAAEPGLR-----------AVVRNLKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKG--------VEETVVWILPFTSGGFLYIALVNVLPDLLEEDDPWHS-------LQQVLLLCSGVLVMVLLSLFVE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H72-1", "uniprot_id": "S39AD_HUMAN", "id": "Q96H72-1", "name": "Zinc transporter ZIP13", "aln": "--------MPGCPCPGCGMAGPRLLFLTALALELLERAGGSQPALRSRGTATACRLDNKESESWGALLSGER------------------------------------------------------------------------------LDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLR---SEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQ-----------------SLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQAPNKDPTAAAAALN---------------GGHCL---------AQPAAEPGLG-----------AVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV-VGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRS-------LQQLLLLCAGIVVMVLFSLFVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW42-1", "uniprot_id": "S39AD_DANRE", "id": "Q8AW42-1", "name": "Zinc transporter ZIP13", "aln": "-----------------------MMIQTAVAQAKTAPAG---PGPWSIK-------DLVDLQYLDELMSIDN------------------------------------------------------------------------------LDVWFCSLVGSIAIGLSGIFPLLVIPIEAGTALK---TEAGCQKLKKLLSFAIGGLLGDVFLHLLPEAWAYTS--SPGG--------------------SHRHYCTQGLWVIGGLMSFLTLEKMFPDEVGDPETKTSFQRTTSSSSDLSSQF------SVSPQTNGICSNNNS----DSKPKTDISPY-----------TQPEKIKTSGYLNLLANCIDNFTHGLAVAGSFLVSRKVGFLTTFAILLHEIPHEVGDFAILLRAGFDRWKAARMQLSTALGGVLGACFALCSQSQHG--------AENATTWILPFTSGGFLYIALVNVVPDLLEETNPRNS-------LLQVLLLFSGIGVMALLSIAMD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAF0-1", "uniprot_id": "S39AD_DROME", "id": "Q9VAF0-1", "name": "Zinc transporter ZIP13 homolog", "aln": "------------------MTTNSSFFDEHIAMIYSNLMD----------------------QYMPEYFKSFE------------------------------------------------------------------------------YTPWVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLPEAWEGDN------QDP-----------------SSHPSLRSGLWVLSGILIFTIVEKIFSGYASADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGACDIEDVGKVCFLREQEQKSKE-----------RKEQPKKVAGYLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLGALVAIGGSGVTS-------AMEARTSWIMPFTAGGFLHIALVTVLPDLLKEEERKES-------IKQLLALVFGIALMAVMTMLFEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40544-1", "uniprot_id": "YKE4_YEAST", "id": "P40544-1", "name": "Zinc transporter YKE4", "aln": "--------------MKASHICSYLLSIAPLVVSHGVHHNRDHGHEANHESKQSFLILKQESIFYSLVCFLQN--------------------------------------------------------------------------HLFVLGPRYNAIVAILIIQLMPCLFVLFVPGLRKNDRA-------SLTLSLLVSFSLGTLLGDILLHVIPESLSGVT-----------------------------DVTMVGGAIFLGFISFLTLDKTMRILSGTSNDDGSIHSHSHS----------------------------------HTPQQTAEKK--------------AGFNMSAYLNVISGIAHHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKATSSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLREFKKWALQLVFIFVGFAVMALMDEH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : : . : .:* * *::*: * ***: :**::*.: * :: *:: * ::* . . : . :.***: :. .::*.*:*:. *: . * :::::: :**:***:******: :* * * ** ..: *: . :***:**::::* ..*:*::* . ", "identical_positions": 49, "similar_positions": 70, "identity": "9.4%" }, { "cls_id": "homologset.agr.SGD:S000001288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXT2-1", "uniprot_id": "D3ZXT2_RAT", "id": "D3ZXT2-1", "name": "Cohesin subunit SA", "aln": "-----------------MIAAPEIPTDFNLLQ----ESETHFSSDTDFEDIEGK-------NQKQGKGKT------CKKGKKGPAEKGKSGNGGGKPPSGPNRMNGHHQQ--NGV-------------------ENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE----IIRKMTEEFDEDSGDYPLTMAGPQWKKFKS-----SFCEFIGVLVRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPE-EDGIMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRV-LTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCN-EEFTIFNRVDISRSQLIDELADKFNRLLED---FLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIE------NGDMPEQIVIHALQCAHYVILWQLAKITESTSTKED----LLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQE----NGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSS--RGSTVRSKKSKP-STGKRKVLEGMQLALPEESSSSDS---MWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM----------------------------QTEHHQTPLDYN--------------------------------------QRGTSIMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMD-ESVLGVSMF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35638-1", "uniprot_id": "STAG2_MOUSE", "id": "O35638-1", "name": "Cohesin subunit SA-2", "aln": "-----------------MIAAPEIPTDFNLLQ----ESETHFSSDTDFEDIEGK-------NQKQGKGKT------CKKGKKGPAEKGKSGNGGGKPPSGSNRMNGHHQQ--NGV-------------------ENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE----IIRKMTEEFDEDSGDYPLTMAGPQWKKFKS-----SFCEFIGVLVRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPE-EDGLMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRV-LTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCN-EEFTIFNRVDISRSQLIDELADKFNRLLED---FLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIE------NGDMPEQIVIHALQCAHYVILWQLAKITESTSTKED----LLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQE----NGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSS--RGSTVRSKKSKP-STGKRKVVEGMQLALPEESSSSDS---MWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM----------------------------QAEHHQTPLDYN--------------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMD-ESVLGVSMF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3U4-1", "uniprot_id": "STAG2_HUMAN", "id": "Q8N3U4-1", "name": "Cohesin subunit SA-2", "aln": "-----------------MIAAPEIPTDFNLLQ----ESETHFSSDTDFEDIEGK-------NQKQGKGKT------CKKGKKGPAEKGKGGNGGGKPPSGPNRMNGHHQQ--NGV-------------------ENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE----IIRKMTEEFDEDSGDYPLTMAGPQWKKFKS-----SFCEFIGVLVRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPE-EDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRV-LTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCN-EEFTIFNRVDISRSQLIDELADKFNRLLED---FLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIE------NGDMPEQIVIHALQCTHYVILWQLAKITESSSTKED----LLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQE----NGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISS--RGSTVRSKKSKP-STGKRKVVEGMQLSLTEESSSSDS---MWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM----------------------------QTEHHQTPLDYN--------------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMD-ESVLGVSMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZR5-1", "uniprot_id": "A0A0R4IZR5_DANRE", "id": "A0A0R4IZR5-1", "name": "Cohesin subunit SA", "aln": "-----------------MIAAPELQTEFHYPQ----DTDTRFSSDTDFDDPDGR-------NAIIGKGK-------AKKGKKGPGEKGK---GMGK---GVGRMNGHHQE--NGM-------------------ENVMLFEVVRLGKSA-MQSVVDDWIESYKHDRDVALLDLINFFIQCSGCKGVVSGEMFRNMQNSE----IIRKMTEEFDEDSGDYPLTMTGPQWKKFKS-----SFCEFIGVLVRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANDRLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYHNRE-----LNAKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLHSSDEVLTAEDCESVYHLVYSAHRPVAVAAGEFLFKKLFSHRDPE-DDSMPKRRGRQSVNANLIKTTVFFFLESELHEHAAYLVDSMWDCAAELLKDWECMISLLLDEPLPGEEALTDRQETALIEILLCTIRQAAECHPPVGRGTGKRV-LTAKEKKTQLDDRTRMTELFAIALPALLAKYSVDAEKVTNLLQLPQFFDLEIYTTGRLEKHLDSLLRQIREIVEKHTDTDVLEACSKTYHSLCN-EEFTIFNRVDIARSQLLDEQVDKFNKLLED---FLQEGEDPDEDDAYQVLSTLKRISAFYNAHDLSKWDLFTSNYKLLNTGIE------NGDMPEQIVVHALQCTHYVILWSLAKVSEGCYKKED----MLTLRKQMRAFCLMCQRYLTS-VNTAVKEQAFTILCDLLLIFSHQIISGGREALEPLVYTPEASLQSELLNFILDHVFIDQDEDSNSTDGQQDDEAGKIEALHKRRNLLAAYCKLIIYNVVEMSTGADIFKQYMRYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMLSE----LGPSFDRSSSAFCGIKELARRFSLTFGLDQLKTREAIAMLHKDGIEFAFKEANPQGDGHPPLNLAFLDILSEFSSKLMRQDKRTVHMYLERFMTFQMALQREDCWLPLISYRNSLQAGGDDDTMSVVSGISS--RGSSVRSKKAKP-ATAKRKLPE-------EESSSSSE---VWMSREQSM-QTPVMMPSPHLTSTIMREPKRLRPEESYMGVYTMTPDQQQQH--------------THPHTPQPQHHQTPMDYNTQVTWMLAQRQQQEEVARQQQERAMNYAKLRSNLQHAIRRGTGLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERSELKPDFFDPASIMD-ESVRSTHFLGYDAFQR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NE13-1", "uniprot_id": "A0A8M1NE13_DANRE", "id": "A0A8M1NE13-1", "name": "Cohesin subunit SA", "aln": "-----------------MIAAQELQADFYQEG----HS---LLSDTDLEDHEGR-------NGKLAKGK---------KGKKSIGEKLKGSEVRGR-------VNGHHQE--NDM-------------------ENLSLFEIVRLGKSA-TQSVVDDWIESYKTDRDSALLELINFFIHCSGCKGTVSFEMFRNMQNSE----IIRKMTEEFDEDSGDYPLAMAGPAWKKFKT-----NLCEFIATLVRQC------------QYSIIYDEYMMDTLISLLTGLSDSQVRAFRHTSTLAAMKMMTALVNVALNLSINLDNTQRQYETERNKSIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFIHRYRDVIAEIRVVCIEEIGMWMKMYSEAFLNDSYLKYVGWTMYDKQGEVRLKCLTALQGLYYSRE-----LNARLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSDEVLMAEDCESVYHLVYSAHRPVAVAAGEFLYKKLFSHHGPE-DEGRP-RRGRQCLNANLIRTTVLFFLESELHEHGAYLVDSLWDCASELLKDWESMISLLLDEPFPGEEALSDAQEVALIEIMFCAVRQTCECHPPIGRGTGKRV-LTAKEKKTQLDDRTKITETFAVALPLLLAKYSMDPEKVTNLLQFPRYFDLEIYTTGRLEKHLDALLRQVRDVVEKHTDTDVLEACSMTFQALCN-DEFTIYNRVDLVRSQMLDEQIDKFHRLLED---FLLEGEEPDEDDTYQVLSTLKRITAFHNAHDLTKWDLFTSNYRLLNSGLQ------NGDMPEQIVAHALQCTHYVILWHLAKVSEGSASKDD----MVLLRRQVRAFCLMCQRYLNS-MSTAVKEQAFTILCDALLIFSYQIVASGREILEPLVFSPDASLQSELLNFILDHVFVEQDED-----GSTDDEAGKIEALHRRRNLLAAFCKLIIFNVVEMKTGADVFKQYMRYYTDYGDIIKETMSKARQIDKIQCAKTLILSLQQLFNEMLSD----LGCNFDRSTSAFCGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPSPQGEGGPPLNLAFLDILSEFSSKLLRQDKKTVHVYLERFMTFQMALQRDDCWLPLISYRNSLQAGADDDTLSVISGMSR----SSARSRRGKPPAASKRKLPD-------EDSSCSSSDVSMWVNRVQTVPHSPVMMSSPHIVSTVLRDAKKLRPEQGYIGVYSMSN---------------------EAQHTPLQQPHQHMDYNSQVAWMMAQKQQQERAN-------LQYGKMRGHIQHTIRRGSGLMEDDEEPIVEDVMMSSEERLDDLNEGMDFDTMDIDLPPSKNRRERSELKQDYFDPSSIMD-DSVLNVSMF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D3E6-1", "uniprot_id": "STAG1_MOUSE", "id": "Q9D3E6-1", "name": "Cohesin subunit SA-1", "aln": "-----------------MITSELP-VLQDSTN----ETTAHSDAGSELEETEV--------KGKRKRGRPGRPPSTNKKPRKSPGEKSRIEAGIRG--AGRGRANGHPQQNGDG--------------------DPVTLFEVVKLGKSA-MQSVVDDWIELYKQDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAE----IIRKMTEEFDEDSGDYPLTMPGPQWKKFRS-----NFCEFIGVLIRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRE-----LFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGKRV-LTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCS-EEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIE------HGAMPEQIVVQALQCSHYSILWQLVKITDGSPSKED----LLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRSKKGRPPLHRKR----------VEDESLDNT----WLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMGEQIQEPES-EHGSE----------------------PDFLHNPQMQISWLGQPKLEDLNRKDRTGMN-----------YMKVR-AGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVM7-1", "uniprot_id": "STAG1_HUMAN", "id": "Q8WVM7-1", "name": "Cohesin subunit SA-1", "aln": "-----------------MITSELP-VLQDSTN----ETTAHSDAGSELEETEV--------KGKRKRGRPGRPPSTNKKPRKSPGEKSRIEAGIRG--AGRGRANGHPQQNGEG--------------------EPVTLFEVVKLGKSA-MQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAE----IIRKMTEEFDEDSGDYPLTMPGPQWKKFRS-----NFCEFIGVLIRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRE-----LFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGKRV-LTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCS-EEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIE------HGAMPEQIVVQALQCSHYSILWQLVKITDGSPSKED----LLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRNKKGRPPLHKKR----------VEDESLDNT----WLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPES-EHGSE----------------------PDFLHNPQMQISWLGQPKLEDLNRKDRTGMN-----------YMKVR-TGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ADB5-1", "uniprot_id": "A0A8I6ADB5_RAT", "id": "A0A8I6ADB5-1", "name": "Cohesin subunit SA", "aln": "-----------------MITSKVGNIILDSTN----ETTAHSDAGSELEETEV--------KGKRKRGRPGRPPSTNKKPRKSPGEKSRIEAGIRG--VGRGRANGHPQQNGEG--------------------DPVTLFEVVKLGKSA-MQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAE----IIRKMTEEFDEDSGDYPLTMPGPQWKKFRS-----NFCEFIGVLIRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRE-----LFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGKRV-LTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCS-EEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIE------HGAMPEQIVVQALQCSHYSILWQLVKITDGSPSKED----LLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRSKKGRPPLHRKR----------AEDESLDNT----WLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMGEQIQEPES-EHGSE----------------------PDFLHNPQMQISWLGQPKLEDLNRKDRTGMN-----------YMKVR-AGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ACD6B6N8-1", "uniprot_id": "A0ACD6B6N8_DANRE", "id": "A0ACD6B6N8-1", "name": "Cohesin subunit SA", "aln": "-----------------MINSDFP-VLQDSSNDGQGDTISLAISVSELDDPEVG-------KGKKKRGRPGKQGAANKKARRSPVDK------------GGRRPNGVAHQNGEGT-------------------DPSTLFEVVKQGKSA-MQSVIDDWIESYKQDRDLALLDLINFFIHCSGCKGTVRIEMFRNMQNAE----IIRKMTEEFDEDSGDYPLTMTGPQWKKFRY-----NFCEFIMVLIRQC------------QYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINQDNTQRQYEAERNKVAGKRANEKLELLLEKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKLYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQTLYTNRE-----LYPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEDALSNEDCENVYHLVYSAHRPVAVAAGEFLHRKLFSRHDPQAEEALAKRRGRNSPNGNLIKMLVLFFLESELHEHAAYLVDSLWDSSHDLLKDWDCMVELLLEDPVQGEEVLGDRHESALIELMVCTIRQAAEAHPPVGRGTGKRV-LTAKEKKTQIDDKNRLTEHLIVALPMLLSKYQVDAEKVANLLQIPQYFDLEVYSSGRMEKHLDALLKQIRVVVEKHAEMEVLEACSKTYSILCS-EEYTIMNRVDIARSQLIDELTDKFAHSVED---LLQEGEEADDDDIYNVLSTLKKLTAFHNAHDLTKWDLFKNCYRLLKMGIE------QGSMPEQIAVQALQCSHYSILWQLVKITEGCPSKDD----LLALRRVVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLVSGGREGLQPLVFNPDGSLQNELLNFVLDHVFIDQDDENQSMEGDEEDEANKIEALHKRRNLLAAFCKLIIYDIVDMPAAADIFKQYMKYYNDYGDIIKETLSKTRQMDKIQCAKTLILSLQQLFNELIQD----QGPNLDRTSSHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKVPNPKGPEYPPPNLAFLEVLCEFSSKLLRQDKKTVHSYLEKFMTEYMMERREDVWLPLIAYRNSLLTGGDDDRLSVTTGASSTSKASTVRSKRGRPPQHKRR----------PDEESVEGS----WVMRNDT-LQTPGGLHTPQLTSTVLRENPRQAADHIPDQDSSEPGSE----------------------PDYMHNPQMQMSWLDQQKMEEVNRKERSGMN-----------YMKSRSAGVRQQVRGLMEDDAEPIFEDVMMSSRGQLEDMNEEFE-DTMVIDLPASRNRRERAELRPDFFDSTAIMEDDPGFGMQMF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70576-1", "uniprot_id": "STAG3_MOUSE", "id": "O70576-1", "name": "Cohesin subunit SA-3", "aln": "MPTLWSPSTQHHGSSSGSESSPLQKSVRRAQMALSPCSSS--ILPCDDRDSQGTAEWD---SPSTNEDSDFEDSLRRNVKKRAAKQPPKAVPAAKHRKKQSRIVSSGNGKNESVP-------------------STNYLFDAVKAARSC-MQSLVDEWLDNYKQDENAGFLELINFFIRACGCKSTVTPEMFKTMSNSE----IIQHLTEEFNEDSGDYPLTAPGPSWKKFQG-----SFCEFVKTLVYQC------------QYSLLYDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEDIEGMMNAIFRGVFVHRYRDILPEIRAICIEEIGYWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQE-----LSLRMELFTNRFKDRMVSMVMDRECEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSDRERRRSPQAQKTFIYLLLAFFMESEHHNHAAYLVDSLWDCAGSYLKDWESLTNLLLQK----DQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKS-LTAKERKLQAYDKMKLAEHLIPLLPQLLAKFSADAENVAPLLQLLSYFDLSIYCTQRLEKHLELLLQQLQEVVVKHVEPEVLEAAAHALYLLCK-PEFTFFSRVDFARSQLVDFLTDRFQQELDD---LMQSS-FLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVD------TGEVPHQVILPALTLVYFSILWTVTHISES-TSHKQ----LMSLKKRMVAFCELCQSCLSD-VDPEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGN---GQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQE----QGPQGLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSHEPPNLAFLELLSEFSPRLFHQDKRLLLSYLEKCLQRVSKAPN-HPWGPVTTYCHSLHP------LEITAEASP---RGPPHSKKRCVEGPCRP----------QEEESSSQE----------ESLQLNSGPTTPTLTSTAVKRKQSLRTVGKKQKGRPGPGPGPGP----------------ELICSQQLLGTQRLKMSSAPCFQIRCDPSGSGLG-------------------KQLTRLSLMEEDEE---EELRLLD--------EEWQRGDKMLHSPSSP-----SEHGLDLLDT-------TELNMEDF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M76-1", "uniprot_id": "STAG3_RAT", "id": "Q99M76-1", "name": "Cohesin subunit SA-3", "aln": "MPTLWSPSTQHHGSSSGSMSSPLRKSVRCAQMALSPCSSN--IQPCDDRDSQGTAEWD---SSSTSEDSDFEDSLRRNVRKRAAKRPPKAIPVAKHPKKQSHIVPGGNDKNKSVP-------------------PTSDLFDAVKAARSC-AQSLVDEWLENYKQDENAGFLELVNFFIRACGCKSTVTPEMFKTMSNSE----IIQHLTEEFNEDSGDYPLTAPGPSWKKFQG-----SFCEFVKTLVCQC------------QYSLLFDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEEIEGMMNAIFRGVFVHRYRDILPEIRAVCIEEIGCWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQE-----LSSRMELFTNRFKDRMVSMVMDRESEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSGRERRRSPQAQRTFIYLLLAFFMESEHHDHAAYLVDSLWDCAGSYLKDWESLTSLLLQK----DQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKS-LTAKERKLQAYDKVKLAEHLIPLLPQLLAKFSADAENVAPLLRLLSYFDLNIYCTQRLEKHLELLLQQLQEVVVKHVEPEVLEAAAHALYLLCK-PEFTFFSRVDFARSQLVDLLTDRFQQELDD---LMQSS-FLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVD------TGEVPHQVILPALTLVYFSILWTVTHISES-TSQKQ----LMSLKKRMVAFCELCQSCLSD-VDPEIQEQAFVLLSDLLLIFSPQMVVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGN---GQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQE----QGPQDLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSREPPNIAFLELLSEFSPRLFHQDKQLLLSYLEKCLQRVSMAPS-HPWGPVTTYCHSLHL------VENTAEASS---QGPPHSKKRCIEVPRRL----------QEEESSSQG----------ESLQLNSGPTTPTLTSTAVKRRQSPRTVGKRQKGGPGPGPGPGPGPGPGPGPGPGPGPGPELICSQQLSGTQRLKMSSAPCFQIRCDPSGSGLG-------------------KQMTRLSLMEEDEE---EELRLLD--------EEWQCGDKLLHSPSSP-----SEHGLDLLDT-------TELNMEDF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJ98-1", "uniprot_id": "STAG3_HUMAN", "id": "Q9UJ98-1", "name": "Cohesin subunit SA-3", "aln": "------------------MSSPLQRAVGDTKRALSASSSSSASLPFDDRDSNHTSEGNGD-SLLADEDTDFEDSLNRNVKKRAAKRPPKTTPVAKHPKKGSRVVHR-HSRKQSEP-------------------PANDLFNAVKAAKSD-MQSLVDEWLDSYKQDQDAGFLELVNFFIQSCGCKGIVTPEMFKKMSNSE----IIQHLTEQFNEDSGDYPLIAPGPSWKKFQG-----SFCEFVRTLVCQC------------QYSLLYDGFPMDDLISLLTGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSVHQDNNQRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRGVFVHRYRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRLKCVKALKGLYGNRD-----LTTRLELFTSRFKDRMVSMVMDREYDVAVEAVRLLILILKNMEGVLTDADCESVYPVVYASHRGLASAAGEFLYWKLFYPECEIRMMGGREQRQSPGAQRTFFQLLLSFFVESELHDHAAYLVDSLWDCAGARLKDWEGLTSLLLEK----DQNLGDVQESTLIEILVSSARQASEGHPPVGRVTGRKG-LTSKERKTQADDRVKLTEHLIPLLPQLLAKFSADAEKVTPLLQLLSCFDLHIYCTGRLEKHLELFLQQLQEVVVKHAEPAVLEAGAHALYLLCN-PEFTFFSRADFARSQLVDLLTDRFQQELEE---LLQSS-FLDEDEVYNLAATLKRLSAFYNTHDLTRWELYEPCCQLLQKAVD------TGEVPHQVILPALTLVYFSILWTLTHISKSDASQKQ----LSSLRDRMVAFCELCQSCLSD-VDTEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFIQPGDLGS---GDSQEDHLQIERLHQRRRLLAGFCKLLLYGVLEMDAASDVFKHYNKFYNDYGDIIKETLTRARQIDRSHCSRILLLSLKQLYTELLQE----HGPQGLNELPAFIEMRDLARRFALSFGPQQLQNRDLVVMLHKEGIQFSLSELPPAGSSNQPPNLAFLELLSEFSPRLFHQDKQLLLSYLEKCLQHVSQAPG-HPWGPVTTYCHSLSP------VENTAETSP---QVLPSSKRRRVEGPAKPN---------REDVSSSQE----------ESLQLNSIPPTPTLTSTAVKSRQPLWGLKEMEEEDGSE---------------------LDFAQGQPVAGTERSRFLGPQYFQTPHNPSGPGLG-------------------NQLMRLSLMEEDEE---EELEIQDES-----NEERQDTDMQASSYSST-----SERGLDLLDS-------TELDIEDF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM62-1", "uniprot_id": "Q9VM62_DROME", "id": "Q9VM62-1", "name": "", "aln": "-------MMARRGGKRIRMDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDK-PPIIDDDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREITT--------------DENSLYYIVRHSKNP-IASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTS----IIRRMTEEFDEESGEYPLIMSGTQWRKFKN-----NFCDFVQTLVKQC------------QYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDE-----LKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFH-LTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGREVLETCAKTLECLCA-EGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENI--DRCLPNEALVYCIEACYFSISWGLQYVENECESVNVT-EVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQ--------DETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQS---EDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANK-EPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHG------------------------------------------------------------------ETDQAPVASKRAYTRKRRDHDEEEEEE--------------------------------------------------------------------------------------------EDEEE----------------------------------------HNDPDYRG-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0F4-1", "uniprot_id": "Q9W0F4_DROME", "id": "Q9W0F4-1", "name": "", "aln": "-----------------MSDISFDDAVLNDSQ------------ASNQMDFEIR-----------------------EECSIAPNDEPVCVDGTVGDATNKSLLQMILSRKRLSP---------------------------TNKRNSH-IESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSD----ILSNSSSHFSNTHIYPLIRKPADVFVNQVG-----SFLN--ALLLVAN------------KFRSDSYQLFLVQLTNFVMACSESNIRTFRHTATMIGLKIMTILSDLKS----------------------------------------LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDVIQCSLDNISVLCRKDV-----LFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMAANRGLAQAAADLFILRRNGLDGET--------------FCQRVKHLLQLFIECG-HEQADYLVDSLID-NCELVLDWKSMIAVLLENP--KSRELSDIHCSSLIAILLAGVKQATAGEIPPGRYTKDLK------REPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFLN-RMIPIPLTKQLLNSAVTNYKMAWHRTQDTS-------PSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHG-NLCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSD--------LMLETNSDQLQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQP-TEATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRP---------------------------------------------------------------------RKTKSYPQAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40541-1", "uniprot_id": "SCC3_YEAST", "id": "P40541-1", "name": "Cohesin subunit SCC3", "aln": "--MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSASNTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEK-KKRPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHNSKSTDNSAIRQVFERFKTKILEVAIR-DVNLDVRIHSIQVLTEASSLGYLDDSEILIISSLMFDEEFDPFKTS-SFNKRSKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLSPYISTHLKTICNLLISDTESNELIQKLQNSAN------NNSDDEDVDDEELDITPLFP---------IDRNSTILYLNVFHGLCAGANNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESFITFSLDDWISIGYETELKKITDKTIKAFMD-------STIGNSKVDMKYDIFAKFIHHIHHFEKKELQEKFLNQIATLKIHLKKFLQEKMDPNNSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATN--------------ETFENINSLFYLKWSACTSLMDIIVAIKIFELKLPADATT---WRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAK-------QVDVQLERVADEDANLNDLPETGFFENIETEFLLFTVKLKGLMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPEPNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEP------------------------------IEESSQNNS-------------ELAPIEEHPTVVDAIDNSDEITQD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: * : * . : ::::.:. .*. : . . :. : .. . : : .: : *: . : : . : . * .::* **: :*: : * . : :.. *: * :* ** .: .:. *: *. .* : *: . : * .* : * . : . ..*: :: : : : : . : * : :: . :: .: :* : ::. : : : * : : . : : . . : : : :* : :* . . : : . . :. : : . .: . . . . : : : . : :. . : : : : . . : . : :: . : : : . * :: . ..:: : :: . : :: . .: . . . :. : :. . : :: *: . : :: : : :: :: . . . ", "identical_positions": 30, "similar_positions": 192, "identity": "2.12%" }, { "cls_id": "homologset.agr.SGD:S000001289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF51-1", "uniprot_id": "EMC5_RAT", "id": "B5DF51-1", "name": "ER membrane protein complex subunit 5", "aln": "MAPSLW-KGLVGVGLFALAHAAFSAAQHRSYMRLTEKEDES-----LPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATS----------ELKNKTFDTLRNHPSFYVFNHRGRVLFR-PSDATNSSNLDALSSNTSLKLRKFDSLRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K273-1", "uniprot_id": "EMC5_MOUSE", "id": "Q8K273-1", "name": "ER membrane protein complex subunit 5", "aln": "MAPSLW-KGLVGVGLFALAHAAFSAAQHRSYMRLTEKEDES-----LPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATS----------ELKNKTFDTLRNHPSFYVFNHRGRVLFR-PSDATNSSNLDALSSNTSLKLRKFDSLRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4V1-1", "uniprot_id": "EMC5_HUMAN", "id": "Q8N4V1-1", "name": "ER membrane protein complex subunit 5", "aln": "MAPSLW-KGLVGIGLFALAHAAFSAAQHRSYMRLTEKEDES-----LPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATS----------ELKNKTFDTLRNHPSFYVFNHRGRVLFR-PSDTANSSNQDALSSNTSLKLRKLESLRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TLE4-1", "uniprot_id": "EMC5_DANRE", "id": "Q6TLE4-1", "name": "ER membrane protein complex subunit 5", "aln": "MASSFW-KGVVGIGLFALAHAAFSAAQHRSYMRLTEKENET-----LPIDIVLQTLLSFVITCYGIVHISGEFKDMDASS----------ELKNKTFDTLRNHPSFYLFNHRGRVLFRTPEQEPSTPNAQALPSNP-LRLRKLENFH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P719-1", "uniprot_id": "MMGT2_RAT", "id": "Q6P719-1", "name": "Membrane magnesium transporter 2", "aln": "MVAWLW-KVLVGVGLSALAHAAFSAAQHRSHTRLAEMKYEP-----LPTDIVLQTLLAFALTCYGVVHTAGDFRDRDATS----------ELKNVTFDTLRNRPSFYVFQHSGSSLLQ-PSDTTRSSNLNVPSSDD-IRLKF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3L0-1", "uniprot_id": "MMGT2_MOUSE", "id": "Q8R3L0-1", "name": "Membrane magnesium transporter 2", "aln": "MVAWLW-KVLMGVGLFALTHAAFSAAQHRSHARLTEKKYEP-----LPADIVLQTLLAFALTCYGVVHTAGDFRDRDATS----------ELKDMTFDTLRNRPSFYVFHRSGYRLFQ-RPDSTHSSNLSASSSD--LPLKF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VJ25-1", "uniprot_id": "Q9VJ25_DROME", "id": "Q9VJ25-1", "name": "Membrane magnesium transporter", "aln": "MGSKLFNKLLLIAGFASLAHAAFSAAHHRTYLRLTEQEWNS-----LPLDIILQTVISLVIVIYNIIEIVGNFKEIRATV----------DMQQKTWDTLGNFPSFYSFNHRGRALNP--GYTPPE----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40540-1", "uniprot_id": "EMC5_YEAST", "id": "P40540-1", "name": "ER membrane protein complex subunit 5", "aln": "--MSFVSKLLYTVSALVLFHSGFSSYEFHHLLKLNSLNNAQGAISKLPKDIMYETYAGLILFVLAVFTSFEKLQYLPIESNDGKIISQGNYLKEIALNKATNVDNLIGSNPNGEIIFT-PSFVDVHMKRKICREWASNTVKKEK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . * *:.**: ..: :* . : ** **: :* .: : :. .:: ::: : :. * .: : * : ", "identical_positions": 13, "similar_positions": 32, "identity": "8.78%" }, { "cls_id": "homologset.agr.SGD:S000001292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M1F1-1", "uniprot_id": "F1M1F1_RAT", "id": "F1M1F1-1", "name": "E3 ubiquitin-protein ligase MARCHF6", "aln": "-----------------------------MDTAEE-DICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHS--------RKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTA---CRIYKCLFTG------------------------------------------------SVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA------------------------------------PPFNAAGHHQNEAPVGGNG-AENPAADQPANPAGENAVLGENPDAQDGQAEEEEEDNEEEDDAGVEDAADANNGAQDDMN-------WNALEWDRAAEELTWERMLGLDGS-----------------------------------------------------LVFLEHVFWVVSLNTLFILVFAFCPYHIGH-----------FSLVGLGFEEHVQ-ASHFEGLITTIVGYILLAITLIICHALATLVKFHR-----------------------------------------------------SRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDI---CSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLR-EVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIK-SLLPHFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQG--HTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEES------------------------------ENSANQQVNNNQPARNNNAVP---------------AGEGLHAAHQAILQQGGPVG---------------------------FQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPAFLFSVFAGRWLMSFWTG-----------------------------------TAKIHELYTAACGLYVCWLTIRAVTVLVAWMPQGR------RVIFQKVKEWSLMIMKTLIVAVLLAG--------------VVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG-PQWWLKTVIEQVYANGIRNIDLHYIIRKLAAPVISVLLLSLCIPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMGILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQG----PSTPPPVSSQE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ89-1", "uniprot_id": "MARH6_MOUSE", "id": "Q6ZQ89-1", "name": "E3 ubiquitin-protein ligase MARCHF6", "aln": "-----------------------------MDTAEE-DICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHS--------RKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTA---CRIYKCLFTG------------------------------------------------SVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA------------------------------------PPFNAAGHHQNEAPVGGNG-AENPAADQPANPAGENAVLGENPDAQDGQAEEEEEDNEEEDDAGVEDAADANNGAQDDMN-------WNALEWDRAAEELTWERMLGLDGS-----------------------------------------------------LVFLEHVFWVVSLNTLFILVFAFCPYHIGH-----------FSLVGLGFEEHVQ-ASHFEGLITTIVGYILLAITLIICHALATLVKFHR-----------------------------------------------------SRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDI---CSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLR-EVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIK-SLLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQG--HTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEEN------------------------------ENSANQQVNNNQPARNNNAVP---------------AGEGLHAAHQAILQQGGPVG---------------------------FQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLP-----VFAGRWLMSFWTG-----------------------------------TAKIHELYTAACGLYVCWLTIRAVTVLVAWMPQGR------RVIFQKVKEWSLMIMKTLIVAVLLAG--------------VVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG-PQWWLKTVIEQVYANGIRNIDLHYIIRKLAAPVISVLLLSLCVPYVIASGAVPLLGVTAEMQNLVHRRIYPFLLMVVVLMGILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQG----PSTPPPVSSQE---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60337-4", "uniprot_id": "MARH6_HUMAN", "id": "O60337-4", "name": "E3 ubiquitin-protein ligase MARCHF6", "aln": "-----------------------------MDTAEE-DICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHS--------RKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTA---CRIYKCLFTG------------------------------------------------SVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA------------------------------------PPFNAAGHHQNEAPAGGNG-AENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMN-------WNALEWDRAAEELTWERMLGLDGS-----------------------------------------------------LVFLEHVFWVVSLNTLFILVFAFCPYHIGH-----------FSLVGLGFEEHVQ-ASHFEGLITTIVGYILLAITLIICHGLATLVKFHR-----------------------------------------------------SRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDI---CSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLR-EVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIK-SVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQG--HTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEEN------------------------------ENSANQQVNNNQHARNNNAIPV--------------VGEGLHAAHQAILQQGGPVG---------------------------FQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLP-----VFAGRWLMSFWTG-----------------------------------TAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGR------RVIFQKVKEWSLMIMKTLIVAVLLAG--------------VVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG-PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQG----SSPPPPQSSQE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QDQ9-1", "uniprot_id": "E9QDQ9_DANRE", "id": "E9QDQ9-1", "name": "E3 ubiquitin-protein ligase MARCHF6", "aln": "-----------------------------MDTAEEADICRVCRSEGTQDKPLYHPCVCTGSIKFIHQECLVQWLKHS--------RKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTA---CRIYKCLFTG------------------------------------------------SVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPLWLEQNQ------------------------------------QQPANAAGPPNEAPGQGNGGAENQPMPAPAEPPAENAAAAEAPDLPADPAEEMELDNEDEDDGGAEDVADANNGAQDDMN-------WNALEWDRAAEELTWERMLGLDGS-----------------------------------------------------LVFLEHVFWVVSLNTLFILVFAFCPYHIGH-----------FSVVGLGFEEYVR-ASHFEGLITTIVGYVLLAITLIVCHGLAALVRFQR-----------------------------------------------------SRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDI---CSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLR-EVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIK-HIFPSFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQG--HTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEDN------------------------------ENNANQQANNNNQQARNNAIPV--------------VGEGLHAAHQAILQQGGPVG---------------------------FQPYHRPMKFPLRIVLLILFMCVTLLLASLVCLTLP-----VFTGRWLMSFWTG-----------------------------------SAKIHELYTAACGLYVCWLSIRAITVLLAWMPQGR------RVILLKIQEWTLMIMKTLIVAVLLAG--------------VIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG-PQWWLKTVIEQVYANGIRNIDLHFIIRKLAAPVIAVLLLSLCIPYVIAVGIVPLLGVTMEMQNLVQRRIYPFLLMVVFLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYERKAGKAS----ASTHSS-SVQE---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W023-1", "uniprot_id": "Q9W023_DROME", "id": "Q9W023-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-----------------------------MDDLSQGDICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYS--------HKEYCELCSYSFSFQPIYAPDMPRVLPIKDVLVGLMSAVLEGARCWLHYTLVGLAWFGVVPLSA---YRTYRYLFRAS-----------------------------------------------SFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGLVWLREQILHGGGPDWLERDD------------------------------------APLQAAAANP----------APDPAAEAAPQPQDDNNNADDN---EAPAPADNDGQDAQAQDAAPAAAAPVVDADADEQN-------WNPMEWDRAAEELTWERLLGLDGS-----------------------------------------------------LVFLEHVFWIISLNTMFIFTFAFCPYCVGN-----------FILSSMDLLQPEKPLLHFHGLITTLFGYCCIGLTLVVLHFFSRVFRLRR-----------------------------------------------------VCWFIGLCYIVVKVSLLSVLEIGVLPLICGWWLDI---CSLPLLDASLKDRKESFKAAPGTSLFVHWMFGMVYVYYFAAFVSLLR-EVLRPGVLWIFRNVNDPDFSPIQEMIHVPIVRHIRRLVASAMIFGFAVLLMLWLPIRILQ-VVCPDFLPY--ALSGDS---AVNLQLLLLQIVLPGFFEQT--QTRIWLKGLLRIWCTAVAWLLGIRSYLLPAPEPEPE-------------------IPAAGEEGVENAAGENENQEGEAADAAAQPPAPPPPPPPPVEPAPAPRNLAAAHQAIMQRDAPVG---------------------------FQPYDKPSLFALRLCALLALMCLSIVCAAMLTLTVP-----VYIGRRLMLIWSSQPDEKAAGAAAAEGAGEVVENLDPIDPEGARKNERLLRSHELYTAELGGYLCWIVCRVVAAVVTLLPQGR------AAIVDKIKHWVRVALQYALPVLTLLGI-----------FVLVPLLIGLLIELAVVIPLRVPLRKTPIHFLWEDWALGVLYCKIAIALTMMG-PDWHLKRALDRAYMDGLRDFDLKFVMRDLAVPVVTTIGLALAIPYVMAHMMFPIFLADAYAQHVVARLVYPVSFIVVGSICILLFQIDQLKKLYLSIKVDKYLVGQRLVNYEHRKKQQQ----QQEEEKEQQRAARELRENQERDREREREQLVQELELAELL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40318-1", "uniprot_id": "DOA10_YEAST", "id": "P40318-1", "name": "ERAD-associated E3 ubiquitin-protein ligase DOA10", "aln": "MDVDSDVNVSRLRDELHKVANEETDTATFNDDAPSGATCRICRGEATEDNPLFHPCKCRGSIKYMHESCLLEWVASKNIDISKPGADVKCDICHYPIQFKTIYAENMPEKIPFSLLLSKSILTFFEKARLALTIGLAAVLYIIGVPLVWNMFGKLYTMMLDGSSPYPGDFLKSLIYGYDQSATPELTTRAIFYQLLQNHSFTSLQFIMIVILHIALYFQYDMIVREDVFSKMVFHKIGPRLSPKDLKSRLKERFPMMDDRMVEYLAREMRAHDENRQEQGHDRLNMPAAAADNNNNVINPRNDNVPPQDPNDHRNFENLRHVDELDHDEATEEHENNDSDNSLPSGDDSSRILPGSSSDNEEDEEAEGQQQQQQPEEEADYRDHIEPNPIDMWANRRAQNEFDDLIAAQQNAINRPNAPVFIPPPAQNRAGNVDQDEQDFGAAVGVPPAQANPDDQGQGPLVINLKLKLLNVIAYFIIAVVFTAIYLAISYLFPTFIGFGLLKIYFGIFKVILRGLCHLYYLSGAHIAYNGLTKLVPKVDVAMSWISDHLIHDIIYLYNGYTENTMKHSIFIRALPALTTYLTSVSIVCASSNLVSRGYGRENGMSNPTRRLIFQILFALKCTFKVFTLFFIELAGFPILAGVMLDFSLFCPILASNSRMLWVPSICAIWPPFSLFVYWTIGTLYMYWFAKYIGMIRKNIIRPGVLFFIRSPEDPNIKILHDSLIHPMSIQLSRLCLSMFIYAIFIVLGFGFHTRIFFPFMLKSNLLSVPEAYKPTSIISWKFNTILLTLYFTKRILESSSYVKPLLERYWKTIFKLCSRKLRLSSFILGKDTPTERGHIVYRNLFYKYIAAKNAEWSNQELFTKPKTLEQAEELFGQVRDVHAYFVPDGVLMRVPSSDIVSRNYVQTMFVPVTKDDKLLKPLDLERIKERNKRAAGEFGYLDEQNTEYDQYYIVYVPPDFRLRYMTLLGLVWLFASILMLGVT------FISQALINFVCSFG------------FLPVVKLLLGERNKVYVAWKELSDISYSYLNIYYVCVGSVCLSKIAKDILHFTEGQNTLDEHAVDENEVEEVEHDIPERDINNAPVNNINNVEEGQGIFMAIFNSIFDSMLVKYNLMVFIAIMIAVIRTMVSWVVLTDGILACYNYLTIRVFGNSSYTIGNSKWFKYDESLLFVVWIISSMVNFGTGYKSLKLFFRNRNTSKLNFLKTMALELFKQGFLHMVIYVLPIIILSLVFLRDVSTKQIIDISHGSRSFTLSLNESFPTWTRMQDIYFGLLIALESFTFFFQATVLFIQWFKSTVQNVKDEVYTKGRALENLPDES", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . **:** *. :.**::** * ****::*:.**: *: . . *::* : : * .**: :** :*.. :: : :. * : *... :: *** : * :: . . * : *:: *:: :. . : : : . : * ::.. :* : : . : :* . : :: : :. :. : * . :. ::* : .:: . * .: :.: : :.:::: : * :* . : .: . :*.:. :.:: : * : :. : . :: ..** * .:*:. :*::.* **: *.: :: : * ::*::* .* :*:::** :: ::* :::*****:::*. :**::. ::: : *: :: *: * .::. ::* : : **: : * : .:: :** : :. : : .: *: : . * : *::* : : : * . : : . .: : . : :: * . : :: : : *::: * :. : .: *: : . * : : :: : :.:*: . :::. : : : . . .:: .:*.: :: : : : * : *:* . :: ::* ..: : * :.: . . : * : . . : * .: :* . :::: : : .. *: : : . :.: : .: : : ", "identical_positions": 101, "similar_positions": 302, "identity": "7.55%" }, { "cls_id": "homologset.agr.SGD:S000001293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BUH8-1", "uniprot_id": "SENP7_MOUSE", "id": "Q8BUH8-1", "name": "Sentrin-specific protease 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLSKLRGSECW-----WTRSLRNKVICLDHKKPKAARGCPP--KGLPKRHLRVMLTNVLWTDLGREFRKTLPRKDANLCAPSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERTPRVILTDIRQTELGRKYLKIPPVTEASLSDTANLKSEQLSSSSDGSLESCQSVN-HHKSFLSESGPKPSRTG-DVPAKEAACGGQKQGDDGGVTPEMAAPHPKDFNTGNKGCDYLEEGTSNKNTSYSYSEMDHTPVSRKRKKRGRSNFHDSHNSKTSLDKPTEHTKEEENDSSVSRKLEESGEDSHQDPAPPEGLAPESLESEATNLRSFAAGQEPDASAASGRASS--PNKSLESSASSEVSENSSVAVKGE-ALTLKEASPPGGSSEESQLLISAEPIVVS----SDEEGPVEHKNSVILKLQPP--HEIMSENQGTSDPQLSELTLGACESVQVTSELFPYNPDVENISCIKSNSEMDLKLDFIFTCVYIGKIKGTPKG-----CVTFTKKYIKIPFQVSTNEISLTVDTARLKRFGLWESK------DEDHSKRSHAILFLWLSSDYLQDIQTQLENPMLSQQSKANEFIFLELNSSISQREELKLKDIMMEISTKNGNLHLSCPLP---WVQALPLFQDLSPQEISFLHYYYASASALPT--AAGADMKKKSVSQPSNSDTIKPTYTFLHK---------------------QSSGCYSLSITSSPEEEWQEVRNTGPVQKLIVYP-------PPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDCPQTVSQQ------------------------------------------------------------------FQGQQSQHDHKMTDNDPHTTSTVSTSAEDSQSTEVNMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKR--KTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIH-LEKWFPRHVIKTKREDIRELILKLHLQQQKGGSC------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF42-1", "uniprot_id": "SENP7_RAT", "id": "D3ZF42-1", "name": "Sentrin-specific protease 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLPKLRGSECW-----WTRSLRNKVICLDHKTTKAAHGCPP--KALPKRHLKVMLTNVLWTDLGREFRKTLPRNDAKLCDTSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERIPRVILTDIRQTELGRKYLKIPSVTEASLSDTASPKSEELSSSADGSLESCQNVN-HLKSFLSERGSKPSRTG-DISAKEAANGRQEQGDDGDIAPEMVTPQSKDFNSGNKG-DYHEEGTSNKNTSYSHSETDHTPVSRKRKKRGRSNFHNSHNPKSSVDKSTEYIKEEENESTVSSKLEESNEDSHQDPAPPEGLTPDSLETEATNVCSFVV-QEPDVSAASGRACS--PNKSSESSVSSEVAENSSAAEKGE-ASTVKEAPPPGGNSEENQLLMSAEPIVVS----SDEEGPVEHKNSVILKLQPSQDYEFMSENQTTSDPQLSELMLGACESVQVSSELCPYNPDMENISCINPNSEMDLKLDFIFTCVYIGKIKGTSKG-----CITFTKKYIKIPFQVSMNEISLTVDTARLKRFGLWESK------DDDHSKRSHAILFLWVSSNYLQDIQTQLENPMLSQQSKANEFIFLELNSPISQREELKLKDIMMEIGATNGELQLSCPLP---WVQAFPLFQDLSPQEISFLHYYCASASSFPA--VAGADMKKKPVSQPSNADVVKPTYTFLHK---------------------QSSGCYSLSITSSPDEEWREVRNTGPVQKLIVYP-------PPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQE------------------------------------------------------------------FQDQQSQHDNKTIDNDPHTTSTVFTSAEESQSTETSMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKR--KTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIH-LEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQF6-1", "uniprot_id": "SENP7_HUMAN", "id": "Q9BQF6-1", "name": "Sentrin-specific protease 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKRKLGRRPSSSEIITEGKRKKSS-SDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQ-YCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNS-QELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVS----SDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKG-----CVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSK------DDNHSKRSHAILFFWVSSDYLQEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLS---WVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQK---------------------QSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYP-------PPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQ------------------------------------------------------------------SQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKL--KTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIH-LEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYJ5-1", "uniprot_id": "Q9VYJ5_DROME", "id": "Q9VYJ5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRKETVSKDQAVRRIAHNDFILVS-RQLLINRAD---TDPDKGSARMLIIYSSGKQHIVTFKLPNLACRVQDLFFQMDLQIDESTTIDCIENAGGIIHLVVSVGFPISDNIAETVAHAEEFYRK--VHQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNGCQPAASATKGKKHK--KSPCGSP--GEN-NDGQVILS-----------ADQDANTNTKAK------KQKKCHIAKDNNGIQAASSHDN------PSSSGNKQ-------------------------------------------------------------GSHNSTAITSNSTMTSNG---------------------------LRG-VQPAEDAPAISQWIQSRNNAAV---------------SKKSEETAGGSQSR------------VQSNVASIS--SPAVKATSDAAIPTPAERAE----------------RSRLRRNRNWILSRD---------------------VDEDAVVLVSSGDEETTAADDGQ--TERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTHIFSTFFHKRLTTRTN---PRNTKQTAAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNN--------------------------------------------------------------------------------------------------------VQTTLSDDIP-IKQPLILIFDSLAVTSRHRAIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCGLYLLQYVEQFFTKPINDYTLPIKELSNWFDLLTVTKKREDIANLIKKLMNESNQQ-RKILPVIKFPTLNGQLVMDEEDSE------EENSKEEHKTTLVCSKDRK-------------------------------PPRRRNTLK---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRY4-1", "uniprot_id": "Q9VRY4_DROME", "id": "Q9VRY4-1", "name": "", "aln": "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-QHVLNNRAGQEIAERDKNSAKMLVILASGEQRLITFTLPRESCTVQDLLEQVGVPFDHNTTIQCVEHRGANVDFVVTVGFTVHESASELISRAEESLQMNRSQENQAAVAGAAAAANSNPATTSASPAYAQANAAAEQAKREAASSASGNTVVGTVSSAGSA--GATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKSYVPKNSAASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGRGSMAMRGGRARGGRRVPEVDPVVLLSSEDEAEGGEGTSDSSNQPTNNSKLNSNGNLHELSAAFPCEPNLPEIDEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRLVPYRFEITEPVCFTTKGVRIAGILKDKDEKFELNIHKQEVIKVIAHFGNVEPAQPLVTLYLLKTCAEYVKNQLKLPDDQHHEHTGFKTHSYHTRRLILLFDSISVSARGNIKSMFSCVDEISSTDAAEILERIADSDRKTQDKSSQPPPRQLRADEQVSLLMYPPKGTGGLCIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFSTFFYKRLTTLTR---PADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYPNLKGPVTFDTNQPVEPQQLKRPRGKKVALQIGNTTITPLTKRAEGGQLPAALTAENVCRIADDESERDEAEGDESDMASEDSENSNSAKEPAATPTSTTASTPSLSSSQPTATGPARNIASDDVPAVKQPLILIFDSLAGASRSRVVATLRDYLTCEYRVKKPDAQAHVFNKDNMPGHCVKVPQQNNFTDCGLYLLQYVEQFFGEPIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDEGNQQQRLILPVIEFPTLNGQLVEYPEDTESAEFEEEEGHDDEDPASEMHDENNAGTDMEVDPVNEEPALAGKTAALAPASTTAAAPTGKRFVLKRRLHNGAVSSPTNGNGEASSNGGALIPQLVSTAAATTTGVSSGVAHLGPRGPSGGLKIRKIEP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B8Q7-1", "uniprot_id": "A0A8M2B8Q7_DANRE", "id": "A0A8M2B8Q7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDTYRESFRQACALLFLQMAVSFRIPKKKQPSDSCSLDMQSPLSRLQDDNSQKSQWGSVTFNGRTPHKTSSNENMLSKDSQRSDS------LRGATRGRFSFKMNQQPIKISPARVNGTPHKVSDTSGFRPQCQTPTTAPDFTANNRWRPKRASDRLLSHDENHTKASECSAFKIHRGLDSEELEEEETEGTQGHSQVKETQRATSSEDYKVTSAASVFEKATSKHKNGTEKAVSKPFNHSG-LHVQEAPARHLRTSEERAASSVPVRKDPLTSETAENKSKDPFASFYSSKLRRKPQSFCKTYKRTKPSSTEPIVLSSDDEGANEVNDVSGGLQEQRISEGIRDTQTGNQK-------SSKTNVGGERSTTKVEVPSIMELEFSRLHYDTIQAQANGTVVITDEGISIPLKDAD-----------------------------------------------------------GEGEVAISISCSQLQMYGMWDGG--------------------LASDGSLLSITEEPAPSLFFLMVSDAQARLLRKELSLQYNTHTSGQACPFVLLVLSG------------QLDDLRVALLASLMDVIGLRYAQDSLSNPVSWADGLSRLLCHPRGEHFLSLLGQNCKDTGQDK--------------------AKENASGIKEPTARRPLRSHSKPQSLPRRLIQYP-------PPPSKGGITVTTEDLECLKDGEFLNDVIIDFYLKYLLLERADKDIAERSHIFSSFFYKQLTRKDTS-GPEETGSTSAYRRHQRVRTWTRHVDIFSKDYLFIPVNHEAHWYLVLICFPALERPQIVEWRQKSSVSQDE----------------------------------------------------------SQTTKERPSGESQRESSQQPKGNPSKINESRSHNLPDCTVHSCTKETICKRPCILIMDSLKLSYHQRTYTLLREYLQVEWEVRK--GSCRSFSNESITGSLCRVPLQDNSSDCGLYLLQYVESFLQNPVVDFALPLR-LDQWFPRSQVRKKREDLRELVLLLYRRQTEPRAT------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40537-1", "uniprot_id": "ULP2_YEAST", "id": "P40537-1", "name": "Ubiquitin-like-specific protease 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSARKRKFNSLKPLDTLNSSRASSPRSSASLPPKRYNTFRKDPKIVDHLNNASTKDFLPVLSMNSESKRQIELSDNDVDNNDEGEGVNSGCSDQDFEPLQSSPLKRHSSLKSTSNGLLFQMSNNLGNGSPEPAVASTSPNGSIISTKLNLNGQFSCVDSKTLRIYRHKAPCIMTFVSDHNHPKFSLYFQQSVIYNSQVNLLDDVELIILDKKNSFMAIILKDLKKVKMILDVNNSSININTNILIWSTASSASNKKIKSIKRFLLMSYSSSIKVEILDHKEQILERLKHLIHPISSSSPSLNMERAINSTKNAFDSLRLKKTKLSTNDDESPQIHTHFLSNKPHGLQSLTKRTRIASLGKKEHSISVPKSNISPSDFYNTNGTETLQSHAVSQLRRSNRFKDVSDPANSNSNSEFDDATTEFETPELFKPSLCYKFNDGSSYTITNQDFKCLFNKDWVNDSILDFFTKFYIESSIEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNN------------------------------------------TDLFSKKYVVIPINISYHWFSCIITNLDAILDFHQNKD------------------KNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISYALDKYSIQLDKTQIKMKTCP---------VPQQPNMSDCGVHVILNIRKFFENPVETIDVWKNSKIKSKHFTAKMINKYFDKNERNSARKN------------------LRHTLKLLQLNYISYLKKENLYEEVMQMEEKKSTNIN------NNENYDDDDEEIQIIENIDQSSKDNNAQLTSEPPCSRSSSISTTEREPTELHNSVVRQPTGEIITD--NEDPVRAASPETASVSPPIRHNILKSSSPFISESANETEQEEFTSPYFGRPSLKTRAKQFEGVSSP-----------------------------------------------------------------IKNDQALSSTHDIMMPSPKPKRIYPSKKIPQLSSHVQSLSTDSMERQSSPNNTNIVISDTEQDSRLGVNSESKNTSGIVNRDDSDVNLIGSSLPNVAEKNHDNTQESNGNNDSLGKILQNVDKELNEKLVDIDDVAFSSPTRGIPRTSATSKGSNAQLLSNYGDENNQSQDSVWDEGRDNPILLEDEDP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . . . . . . . . : . . . . : .: .. : : : . . *: : : :.:..:.. : : : : . : : .. :: . *. : :. : . ::. : : :.. : .: . . : : :: . * : . . . : : : : : : . * . . ", "identical_positions": 4, "similar_positions": 88, "identity": "0.22%" }, { "cls_id": "homologset.agr.SGD:S000001295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31324-1", "uniprot_id": "KAP3_MOUSE", "id": "P31324-1", "name": "cAMP-dependent protein kinase type II-beta regulatory subunit", "aln": "--------------------MS------IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAA-------EAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEE-NGAVEIARCFRGQYFGELALVTNKPRAASAHAIG-TVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12369-1", "uniprot_id": "KAP3_RAT", "id": "P12369-1", "name": "cAMP-dependent protein kinase type II-beta regulatory subunit", "aln": "--------------------MS------IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGTPSKGVNFAEEPMRSDSENGEEEEAA-------EAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEE-NGAVEIARCLRGQYFGELALVTNKPRAASAHAIG-TVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31323-1", "uniprot_id": "KAP3_HUMAN", "id": "P31323-1", "name": "cAMP-dependent protein kinase type II-beta regulatory subunit", "aln": "--------------------MS------IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAP-----ADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEE-NGAVEIARCSRGQYFGELALVTNKPRAASAHAIG-TVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12367-1", "uniprot_id": "KAP2_MOUSE", "id": "P12367-1", "name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "aln": "--------------------MSH-----IQIPPGLTELLQGYTVEVG-QQPPDLVDFAVEYFTRLR-EARRQESDTFIVSPTT---FHTQESSAVP-----VIEEDGESDSDS--------------EDADLEVPVPSKFTRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYGVG-DVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMDPGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12368-1", "uniprot_id": "KAP2_RAT", "id": "P12368-1", "name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "aln": "--------------------MSH-----IQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLR-EARRQESDSFIAPPTT---FHAQESSGVP-----VIEEDGESESDS--------------DDEDLEVPIPSKFTRRVSVCAETFNPDEEE-DNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSDGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSKTKTNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYAVG-DVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLLDPGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13861-1", "uniprot_id": "KAP2_HUMAN", "id": "P13861-1", "name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "aln": "--------------------MSH-----IQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLR-EARAPASVLPAATPRQSLGHPPPEPGPDR-----VADAKGDSESE---------------EDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVG-DVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P81900-1", "uniprot_id": "KAPR2_DROME", "id": "P81900-1", "name": "cAMP-dependent protein kinase type II regulatory subunit", "aln": "--------------------MSSDSSRRIQVPEELKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQ--SERPSVS------------HTDQS----------TDDQLSVNSQ----------------DADAEPPVMAS-SRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYIN----DKHINTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQD--------DAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQLVKIFGSKNNITDTR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12849-1", "uniprot_id": "KAP1_MOUSE", "id": "P12849-1", "name": "cAMP-dependent protein kinase type I-beta regulatory subunit", "aln": "--------MASPSCFHSEDEDSLKGCEMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQILARQ------------------------KSNSQCDSHDEE--------------ISPTPPNPVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVN----GEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPN------EEYVEVGRLGPSDYFGEIALLLNRPRAATVVARG-PLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31321-1", "uniprot_id": "KAP1_HUMAN", "id": "P31321-1", "name": "cAMP-dependent protein kinase type I-beta regulatory subunit", "aln": "--------MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQ------------------------KSNSQSDSHDEE--------------VSPTPPNPVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVN----GEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPN------EEYVEVGRLGPSDYFGEIALLLNRPRAATVVARG-PLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5I0F6-1", "uniprot_id": "KAP0_DANRE", "id": "Q5I0F6-1", "name": "cAMP-dependent protein kinase type I-alpha regulatory subunit", "aln": "--------MASSSTS-SEEERSLRECERYVQKHNIQQLLKDCIVQLCTARPERPMAYLRDYFEKLELEEAKQMVSQQ------------------------KSSSRSDSREDE--------------VSP-PMNPVVKGRRRRGAISAEVYT--EEDATSYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVIDQGEMDVYVN----NEWVTSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALETVQFEDGQKIVVQGQPGDEFFIILEGSAAVLQRRSEN------EEFVEVGRLAPSDYFGEIALLMNRPRAATVVARG-PLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16905-1", "uniprot_id": "KAPR1_DROME", "id": "P16905-1", "name": "cAMP-dependent protein kinase type I regulatory subunit", "aln": "---------MSYMMAKTLEEQSLRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVKLDASRQ------------------------VISP---DDCED--------------LSPMPQTAAPPVRRR-GGISAEPVT--EEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVN----SELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEG------EDPAEVGRLGSSDYFGEIALLLDRPRAATVVARG-PLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07278-1", "uniprot_id": "KAPR_YEAST", "id": "P07278-1", "name": "cAMP-dependent protein kinase regulatory subunit", "aln": "MVSSLPKESQAELQLFQNEINAANPSDFLQFSANYFNKRLEQQRAFLKAREPEFKAKNIVLFPEPEESFSRPQSAQSQSRSRSSVMFKSPFVNEDPHSNVFKSGFNLDPHEQDTHQQAQEEQQHTREKTSTPPLPMHFNAQRRTSVSGETLQP-NNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVN----DNKVNSSGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQG-----------VINKLKDHDYFGEVALLNDLPRQATVTATK-RTKVATLGKSGFQRLLGPAVDVLKLNDPTRH------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : * . . : . * .: .* : * . * :: . .** *: .. :::.: . :* **::** ***:: * .. :. . : . . ******:*. *****: * : **.:** ::*:*:: . :** *::.::. :..:::* :* .:.* : :. *: *: :* .: :::: * . : : : :****:**: . ** *:. . * :. *:*:***. :::* * . ", "identical_positions": 63, "similar_positions": 100, "identity": "13.97%" }, { "cls_id": "homologset.agr.SGD:S000001296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI32-1", "uniprot_id": "CAPZB_RAT", "id": "Q5XI32-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47756-2", "uniprot_id": "CAPZB_HUMAN", "id": "P47756-2", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUB3-1", "uniprot_id": "A0A8M3AUB3_DANRE", "id": "A0A8M3AUB3-1", "name": "F-actin-capping protein subunit beta", "aln": "MNEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYEPPID-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTTKTG-SGTMNLGGSLTRQMEKDETVSES-------SPHIANIGRLVEEMENKIRSTLNEIYFGKTKDIVNGLRSIESLPDNQKYRQLQRELSQVLTQRQIYID---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47757-1", "uniprot_id": "CAPZB_MOUSE", "id": "P47757-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48603-1", "uniprot_id": "CAPZB_DROME", "id": "P48603-1", "name": "F-actin-capping protein subunit beta", "aln": "MSEMQMDCALDLMRRLPPQQIEKNLIDLIDLAPDLCEDLLSSVDQPLKIAKDKE-HGKDYLLCDYNRDGDSYRSPWSNSYYPPLE-----DGQMPSERLRKLEIEANYAFDQYREMYYEGGVSSVYLWDLD------HGFAAVILIKKAGDGSKMIRGCWDSIHVVEVQEK-TTGRTAHYKLTSTAMLWLQTNKQG-SGTMNLGGSLTRQQEQDANVSES-------SPHIANIGKMVEEMENKIRNTLNEIYFGKTKDIVNGLRSTQSLADQRQQAAMKQDLAAAILRRNVKPESN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13517-1", "uniprot_id": "CAPZB_YEAST", "id": "P13517-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDAQFDAALDLLRRLNPTTLQENLNNLIELQPNLAQDLLSSVDVPLSTQKDSADSNREYLCCDYNRDIDSFRSPWSNTYYPELSPKDLQDSPFPSAPLRKLEILANDSFDVYRDLYYEGGISSVYLWDLNEEDFNGHDFAGVVLFKKNQSD----HSNWDSIHVFEVTTSPSSPDSFNYRVTTTIILHLDKTKTDQNSHMMLSGNLTRQTEKDIAIDMSRPLDVIFTSHVANLGSLIEDIESQMRNLLETVYFEKTRDIFH--QTKNAAIASSAEEANKDAQAEVIRGLQSL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *:*.****:*** * :::** :**:* *.*.:******* **. :*. .::** ****** **:******.* * :. *. :** *****: ** :** **::*:***:********: *.**.*:*:** .. :. ******.** . :: : :*::*:* :* *:..* . .. * *.*.**** *:* :. . :.*:**:* ::*::*.::*. *: :** **:**.: :: :: . : .: : ", "identical_positions": 116, "similar_positions": 88, "identity": "38.93%" }, { "cls_id": "homologset.agr.SGD:S000001297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54833-1", "uniprot_id": "CSK22_MOUSE", "id": "O54833-1", "name": "Casein kinase II subunit alpha'", "aln": "----------------MPGPAAGSRARVYAEVNSLR-----SREYWDYEAHVP------------------------------SWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLR--------------------------------------GGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVS-PEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCAEN------TVLSSG-------------------------LTAAR--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FH41-1", "uniprot_id": "F7FH41_RAT", "id": "F7FH41-1", "name": "Casein kinase II subunit alpha", "aln": "VSSASSSSLFAAAAAAAPLPAGGCRCRCRCRHHRLWGPRAERRPPRSTNPAVPPAAEGPGPAWPAPPAPPARASVRPPAPAGPAWRGRPPPPRSSSCSGGPRPAASRACRPALRAAPPPPSAPRGAPRSRPPCPARPRAVGPGSTPSNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLR--------------------------------------GGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDDLYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVS-PEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCAEN------TVLSSG-------------------------LTAAR--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19784-1", "uniprot_id": "CSK22_HUMAN", "id": "P19784-1", "name": "Casein kinase II subunit alpha'", "aln": "----------------MPGPAAGSRARVYAEVNSLR-----SREYWDYEAHVP------------------------------SWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLR--------------------------------------GGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVS-PEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADN------AVLSSG-------------------------LTAAR--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68400-1", "uniprot_id": "CSK21_HUMAN", "id": "P68400-1", "name": "Casein kinase II subunit alpha", "aln": "--------------MSGPVPSRA---RVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLR--------------------------------------GGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS-PEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSS-MPGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NEV1-1", "uniprot_id": "CSK23_HUMAN", "id": "Q8NEV1-1", "name": "Casein kinase II subunit alpha 3", "aln": "--------------MSGPVPSRA---RVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLR--------------------------------------GGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYDQLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS-PEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSS-MPGGSTPVSSANVMSG--ISSVPTPSPLGPLAGSPVIAAANPLGMPVPAATGAQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60737-1", "uniprot_id": "CSK21_MOUSE", "id": "Q60737-1", "name": "Casein kinase II subunit alpha", "aln": "--------------MSGPVPSRA---RVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLR--------------------------------------GGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS-PEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSTS-MAGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19139-1", "uniprot_id": "CSK21_RAT", "id": "P19139-1", "name": "Casein kinase II subunit alpha", "aln": "--------------MSGPVPSRA---RVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLR--------------------------------------GGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS-PEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSAG-MAGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B6B1-1", "uniprot_id": "A0A8M2B6B1_DANRE", "id": "A0A8M2B6B1-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------MSGPVTSRS---RVYPDVNTQR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLR--------------------------------------GGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS-TEALDFLDKLLRYDHQARLTAREAMEHPYFYPIVKDQARMGSTSGLSTGSTPVSTSSMITAGGVTSLSSSQPMANMAGSPVISSPSALATQVPAAAGAQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08181-1", "uniprot_id": "CSK2A_DROME", "id": "P08181-1", "name": "Casein kinase II subunit alpha", "aln": "--------------MT--LPSAA---RVYTDVNAHK-----PDEYWDYENYVV------------------------------DWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLR--------------------------------------GGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVS-PEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15790-1", "uniprot_id": "CSK21_YEAST", "id": "P15790-1", "name": "Casein kinase II subunit alpha", "aln": "--------------MKCRVWSEA---RVYTNINKQR-----TEEYWDYENTVI------------------------------DWS------------------------------------------------------------TNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMD-QYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . : * * * .**:: .*:*********:.::: .. : *:*:************:*** :* * .*** * :***:*:****:**:::*.**: ** *:* :**:*::*:********* ****************:::************** *********:**********:*******:* :* *******::****** .* ****:*.*.***.:: *: **.* * .* *: :: ** *..*::. *:** . * :*::*:****** ****:*** **:* .: : . ", "identical_positions": 183, "similar_positions": 77, "identity": "33.52%" }, { "cls_id": "homologset.agr.SGD:S000001300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUV9-1", "uniprot_id": "D3ZUV9_RAT", "id": "D3ZUV9-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAAN-ANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQD-RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNA---SGPSNAQPRPPSAQPSGGSGGGSGG--SSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNP----APSTLKESSTAAPSGAGSVASGS----GNNSGGPSLLVPLPVNP--------------PSSPTPSFSEAKAAG-------------TLLNGPPQFSTTPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQISAPLFVHSLTTFFPGQGTYIYFDYEKWGQRKKEGFTFEYRYLED--------RDLQ--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0V4-1", "uniprot_id": "CNOT3_MOUSE", "id": "Q8K0V4-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAAN-ANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQD-RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNA---SGPSNAQPRPPSAQPSGGSGGGSGG--SSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNP----APSTSKESSTAAPSGAGNVASGS----GNNSGGPSLLVPLPVNP--------------PSSPTPSFSEAKAAG-------------TLLNGPPQFSTTPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE-----------------QGTYIYFDYEKWGQRKKEGFTFEYRYLED--------RDLQ--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75175-1", "uniprot_id": "CNOT3_HUMAN", "id": "O75175-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAAN-ANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQD-RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAP---SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNP----PPSTSKEPSAAAPTGAGGVAPGS----GNNSGGPSLLVPLPVNP--------------PSSPTPSFSDAKAAG-------------ALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE-----------------QGTYIYFDYEKWGQRKKEGFTFEYRYLED--------RDLQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06102-1", "uniprot_id": "NOT3_YEAST", "id": "P06102-1", "name": "General negative regulator of transcription subunit 3", "aln": "-MAHRKLQQEVDRVFKKINEGLEIFNSYYERHESCTNNPSQKDKLESDLKREVKKLQRLREQIKSWQSSPDIKDKDSLLDYRRSVEIAMEKYKAVEKASKEKAYSNISLKKSETLDPQERERRDISEYLSQMIDELERQYDSLQVEIDKLLLLNKKKKTSSTTNDEKKEQYKRFQARYRWHQQQMELALRLLANEELDPQDVKNVQDDINYFVESNQDPDFVEDETIYDGLNLQ--SNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAVKTSIKSPRSSADNLLPSLQKSPSSATPETPTNVHTHIHQTPNGITGATTLKPATLPAKPAGELKWAVAASQAVEKDRKVTSASSTISNTSTKTPTTAAATTTSSNANSRIGSALNTPKLSTSSLSLQPDNTGASSSAATAAAVLAAGAAAVHQNNQAFYRNMSSSHHPLVSLATNPKSEHEVATTVNQNGPENTTKKVMEQKEEESPEERNKLQVPTFGVFDDDFESDRDSETEPEEEEQPSTPKYLSLEQREAKTNEIKKEFVSDFETLLLPSGVQEFIMSSELYNSQIESKITYKRSRDMCEISRLVEVPQGVNPPSPLDAFRSTQQWDVMRCSLRDIIIGSERLKEDSSSIYAKILENFRTLEMFSLFYNYYFAITPLEREIAYKILNERDWKVSKDGTMWFLRQGEVKFFNEICE-----------------VGDYKIFKLDDWTVIDKINFRLDYSFLQPPVDTASEVRDVSVDNNNVNDQSNVTLEQQKQEISHGKQLLKQLKQGKISV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**** *:** :**:.**:* *:. ::: ...:* ..**:* *:***:*:*******:***:* :* :**** .*:: *: :* **::*.**: :* ****: .* ::.:** ::*:.::.::*:: ** *: * *.:: *::.* : .:*** .. .:* : * **. ::*:* : :* **:* *:.: : :::::**::*:*:*.***** *:* :**.*:*: .: :* . ..: :: *::*.: * . * :. . . .:::. * . .. : .: . * .*.* .::. . **..* :: . . :.. :* :... * *. . :** : ... .:: . :*.:. :* . ..:*:* . .. : ..... :...: .* :*. .:..* :.:. .* *. .: *...* . :* ..*: .::. .:**. * .. * *.. **.*..** *...* .. : * :::. : . .* :. * .. .. .. : : . .::: : :* .:.. .. * *::: :: . :: * . :. . : ..: : :* * : :.: .. ::. :* :: *. :**: :*: . : :* * *:::.*:. .. *** *: * * :.: * * * *. :.* .* .* ::* :*: **:. ", "identical_positions": 170, "similar_positions": 313, "identity": "19.86%" }, { "cls_id": "homologset.agr.SGD:S000001304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00972-1", "uniprot_id": "BCKD_RAT", "id": "Q00972-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "------------MILTSVLGSGPRSGSSLWPLLG---------SSLSLRVRSTSATDTHHVELARERSKTVTSFYNQSAIDVVAEKPSVRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAH---RIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFP--PIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIE------DEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAA-------RFPFIPMPLDYILPELLKNAMRATMESHLDTPYN-VPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDG---------REESFRI------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55028-1", "uniprot_id": "BCKD_MOUSE", "id": "O55028-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "------------MILTSVLGSGPRSWSSLWPLLG---------SSLSLRARSTSATDTHHVELARERSKTVTSFYNQSAIDVAAEKPSVRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAH---RIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFP--PIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIQ------DEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAA-------RFPFIPMPLDYILPELLKNAMRATMESHLDTPYN-VPDVVITIANNDIDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRINPLFGHLDMHSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDG---------REESFRI------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14874-1", "uniprot_id": "BCKD_HUMAN", "id": "O14874-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "------------MILASVLRSGPGGGLPLRPLLG---------PALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAH---RIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFP--PIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIE------DEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAA-------RFPFIPMPLDYILPELLKNAMRATMESHLDTPYN-VPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDG---------REESFRI------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BFP9-1", "uniprot_id": "PDK1_MOUSE", "id": "Q8BFP9-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "aln": "------------MRLARLLRGGTSVRPLCAVPCASRSLASASASGSGPASELGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKT------------------------SFMFLRQELPVRLAN---IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQGVTEYKESFG--VDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKG--SPSHRKHIGSINPNCDVVEVIKDGYENARRLCDLYYVNSPELELEELNAK-SPGQTIQVVYVPSHLYHMVFELFKNAMRATMEHH-ADKGV-YPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVET--------------SRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESVERLPVYNKAAWKHYKANHEADDWCVPSREPKDMTTFRSS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63065-1", "uniprot_id": "PDK1_RAT", "id": "Q63065-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "aln": "------------MRLARLLRGGTSVRPLCAVPCASRSLASDSASGSGPASESGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKT------------------------SFMFLRQELPVRLAN---IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQGVTEYKESFG--VDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKG--SPSHRKHIGSINPNCDVVEVIKDGYENARRLCDLYYVNSPELELEELNAK-SPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHH-ADKGV-YPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVET--------------SRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESIERLPVYNKAAWKHYRTNHEADDWCVPSREPKDMTTFRSS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15118-1", "uniprot_id": "PDK1_HUMAN", "id": "Q15118-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "aln": "------------MRLARLLRGAALAGPGPGLRAAGFSRSFSSDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKT------------------------SFMFLRQELPVRLAN---IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFG--VDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAK-SPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHH-ANRGV-YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVET--------------SRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JK42-1", "uniprot_id": "PDK2_MOUSE", "id": "Q9JK42-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWVRALLK----------------------NASLAG----APKYIEHFSKFSPSPLSMKQFLDFGSSNACEKT------------------------SFTFLRQELPVRLAN---IMKEINLLPDRVLGTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYG--DDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTN--PAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNAT-NANQPIHMVYVPSHLYHMLFELFKNAMRATVESH-ESSLT-LPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG---------------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64536-1", "uniprot_id": "PDK2_RAT", "id": "Q64536-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWFRALLK----------------------NASLAG----APKYIEHFSKFSPSPLSMKQFLDFGSSNACEKT------------------------SFTFLRQELPVRLAN---IMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYG--DDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTN--PAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNAT-NATQPIHMVYVPSHLYHMLFELFKNAMRATVESH-ESSLT-LPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG---------------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15119-1", "uniprot_id": "PDK2_HUMAN", "id": "Q15119-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWVWALLK----------------------NASLAG----APKYIEHFSKFSPSPLSMKQFLDFGSSNACEKT------------------------SFTFLRQELPVRLAN---IMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYG--DDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTN--PAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAA-NSKQPIHMVYVPSHLYHMLFELFKNAMRATVESH-ESSLI-LPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG---------------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q154-1", "uniprot_id": "A0A8M1Q154_DANRE", "id": "A0A8M1Q154-1", "name": "Protein-serine/threonine kinase", "aln": "------------MKFVRFIMK----------------------NAALAN----VPHHIEHFSKFSPSPLSMKQFLDFGSTNACEKT------------------------SFVFLRQELPVRLSN---IMKEINLLPKRLLTTPSVQMVHSWYIQSLMEILEFLEKSPDDHSILEEFVAALVNIRNRHNDVVPTMAQGVIEYKEVFG--QDPVTNQNIQYFLDRFYLSRISIRMLINQHTLVFDGATN--PVHPNTIGSIDPHCQVADVVKDAYESARMLCDQYYLNSPDLDLQELNTN-NRNQPISIVYVPSHLYHILFELFKNAMRATIESH-KEGSN-LPAIQVMVAVGGEDLTIKMSDRGGGVPFRKMENLFSYMYSTAPTPQMDE--------------KQRAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGHGTDAVIHLKALSTDSVERLPVFNKTARRNYEVTQGADDWCVPSREPLDLAVFKLAK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70571-1", "uniprot_id": "PDK4_MOUSE", "id": "O70571-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial", "aln": "------------MKAARFVMR----------------------SASSLSSASLVPREVELFSRYSPSPLSMKQLLDFGSENACERT------------------------SFAFLRQELPVRLAN---ILKEIDILPDRLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKALSEFVDTLVKVRNRHHNVVPTMAQGILEYKDTCT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSK---TGNPSHIGSIDPNCDVVAVVQDAFECAKMLCDQYYLTSPELNLTQVNGK-FPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQ-ENRPS-LTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDN--------------SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESVEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEKLAV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54937-1", "uniprot_id": "PDK4_RAT", "id": "O54937-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial", "aln": "------------MKAARFVMR----------------------SASSLGNAGLVPREVELFSRYSPSPLSMKQLLDFGSENACERT------------------------SFSFLRQELPVRLAN---ILKEIDILPEHLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKVLSDFVDTLVKVRNRHHNVVPTMAQGILEYKDNCT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSK---TGNPSHIGSIDPNCDVVAVVEDAFECAKMLCDQYYLTSPELKLTQVNGK-FPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQ-ENRPF-LTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDN--------------SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSKEPKNLSKEKLAV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16654-1", "uniprot_id": "PDK4_HUMAN", "id": "Q16654-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial", "aln": "------------MKAARFVLR----------------------SAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERT------------------------SFAFLRQELPVRLAN---ILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQ---TGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGK-FPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQ-ENQPS-LTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDN--------------SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q922H2-1", "uniprot_id": "PDK3_MOUSE", "id": "Q922H2-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "aln": "------------MRLFYRLLK------------------------------QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKT------------------------SYMFLRKELPVRLAN---TMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPRVLDNFLNVLINIRNRHNDVVPTMAQGVIEYKEKFG--FDPFISSNIQYFLDRFYTNRISFRMLINQHTLLFGGDTN--PAHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAK-APNKPIQVVYVPSHLFHMLFELFKNSMRATVELH-EDKKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEP--------------TRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQDKIKSNRTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15120-1", "uniprot_id": "PDK3_HUMAN", "id": "Q15120-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "aln": "------------MRLFRWLLK------------------------------QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKT------------------------SYMFLRKELPVRLAN---TMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFG--FDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTN--PVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAK-APDKPIQVVYVPSHLFHMLFELFKNSMRATVELY-EDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEP--------------TRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91622-1", "uniprot_id": "PDK_DROME", "id": "P91622-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial", "aln": "------------MRLFPVRFS------------------------AASSSMASLAKMLDFYSGFNPSPLSIKQFMDFG-QNACEKK------------------------SYIFLRKELPVRLAN---IMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEP-THDNLQKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNP---HAGGRHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSD--------------LHTVPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATVPTGDWSNQVKYAKKKKTSAVNQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40530-1", "uniprot_id": "PDK1_YEAST", "id": "P40530-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 1, mitochondrial", "aln": "MWKIMRSWKCGGMRWAHRQRPSHELLSQLS-------------FDQHYKIRSNIELLIQDYASKPIAPLNYEYFLQYRPPLTKKEE-------------------------YMLTIKTINLLLSLTCKRLNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIAY--PYELHNPPKIQAKFTELLDDHEDAIVVLAKGLQEIQSCYP-------KFQISQFLNFHLKERITMKLLVTHYLSLMAQNKG--DTNKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQRTPVLIHPPSQ-----DITFTCIPPILEYIMTEVFKNAFEAQIALG----KEHMPIEINLLKPDDDELYLRIRDHGGGITPEVEALMFNYSYSTHTQQSADSESTDLP-------GEQINNVSGMGFGLPMCKTYLELFGGKIDVQSLLGWGTDVYIKLKGPSKTALLSKK---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . : : . . : : : :: :. . ** : . . *:::: : . . : : *.:.: :*:*: * :. . : **: .*: ::* .:: : :* : ::.. : . :* : : :* * ::: *::**::.* : . : . :: ::: * ***:. ::.* ::* : * *:*** .: * . : *.: : * * ***. : :: . ", "identical_positions": 38, "similar_positions": 97, "identity": "7.54%" }, { "cls_id": "homologset.agr.SGD:S000001305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCN2-1", "uniprot_id": "NB5R3_MOUSE", "id": "Q9DCN2-1", "name": "NADH-cytochrome b5 reductase 3", "aln": "MGAQLSTLSHVVLSP-VWFIYSLFMK--------LFQRSTP-----AITLENPDIKYP-LRLIDKEVISPDTRRFRFALPSPQ----------HILGLPIGQHIYLSTRIDGNLVIRPYTPVSSD-DDKGFVDLVVKVYFKDTHPKFPAGGKMSQYLENMKIGDTIEFRGPNGLLVYQGKGKFAIRADKKSNPVVRTVKSVGMIAGGTGITPMLQVIRAVLKDPN-DHTVCYLLFANQSEKDILLRPELEELRNEHSARFKLWYTVDKAPD----------------------AWDYSQGFVNEEMIRDHLPTPGEE-PLILMCGPPPMIQFACLPNLER-------VGHPKERCFTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20070-1", "uniprot_id": "NB5R3_RAT", "id": "P20070-1", "name": "NADH-cytochrome b5 reductase 3", "aln": "MGAQLSTLSRVVLSP-VWFVYSLFMK--------LFQRSSP-----AITLENPDIKYP-LRLIDKEIISHDTRRFRFALPSPQ----------HILGLPIGQHIYLSTRIDGNLVIRPYTPVSSD-DDKGFVDLVVKVYFKDTHPKFPAGGKMSQYLENMNIGDTIEFRGPNGLLVYQGKGKFAIRADKKSNPVVRTVKSVGMIAGGTGITPMLQVIRAVLKDPN-DHTVCYLLFANQSEKDILLRPELEELRNEHSSRFKLWYTVDKAPD----------------------AWDYSQGFVNEEMIRDHLPPPGEE-TLILMCGPPPMIQFACLPNLER-------VGHPKERCFTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00387-1", "uniprot_id": "NB5R3_HUMAN", "id": "P00387-1", "name": "NADH-cytochrome b5 reductase 3", "aln": "MGAQLSTLGHMVLFP-VWFLYSLLMK--------LFQRSTP-----AITLESPDIKYP-LRLIDREIISHDTRRFRFALPSPQ----------HILGLPVGQHIYLSARIDGNLVVRPYTPISSD-DDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPD-DHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPE----------------------AWDYGQGFVNEEMIRDHLPPPEEE-PLVLMCGPPPMIQYACLPNLDH-------VGHPTERCFVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY12-1", "uniprot_id": "NB5R2_RAT", "id": "Q6AY12-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "----------------------------------MSVKKKD-----LITLQDPEAKYP-LPLIEKEQINHNTRRFRFGLPSPD----------HVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKTDKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDTS-DGTRMSLLFANQTEEDILLRKELEEVATTHQNQFSLWYTLDRPPS----------------------GWEYSSGFITADMIKEHLPPPGEA-TLILVCGPPPLIQEAAHPSLEQ-------LGYTKDMIFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3KNK3-1", "uniprot_id": "NB5R2_MOUSE", "id": "Q3KNK3-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "----------------------------------MSVKKKD-----LITLQDPEAKYP-LPLIEKEQISHNTRRFRFGLPSPD----------HVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKANKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDTS-DETRMSLLFANQTEEDILLRKELEEVATTHHKQFNLWYTLDRPPS----------------------DWKYSSGFVSADMIKEHLPPPGED-TLILVCGPPPLIQAAAHPSLEQ-------LSYTKDMIFIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6BCY4-1", "uniprot_id": "NB5R2_HUMAN", "id": "Q6BCY4-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "----------------------------------MNSRRRE-----PITLQDPEAKYP-LPLIEKEKISHNTRRFRFGLPSPD----------HVLGLPVGNYVQLLAKIDNELVVRAYTPVSSD-DDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPS-DRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPI----------------------GWKYSSGFVTADMIKEHLPPPAKS-TLILVCGPPPLIQTAAHPNLEK-------LGYTQDMIFTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P487-1", "uniprot_id": "NB5R2_DANRE", "id": "Q0P487-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "MDILTAPVLIGVSIV-VITVLYLFLKPAGSNSTPPKPQNKI-----PKALQDPSVKYP-LPLIEKEEINHDTKRFRFGLPSSS----------HVLGLPIGQHIYLSAKVNGSLVVRAYTPVSSD-QDQGYVDLVVKVYYKNTHPSYPDGGKMSQYLDNMKIGDTIDFRGPNGLLVYNGKGKFAIRPDKKSEAEVRKFKHVAMIAGGTGITPMLQLIRSITADSF-DETVCSLIFANQTEKDILLRNELDEVHRNHPSKLKLWYTLDRPSE----------------------GWKYSEGFVNAAMMKDHLPPADSD-VLVVMCGPPAMIEKACLPNLLK-------LGYKKENIFAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DB73-1", "uniprot_id": "NB5R1_MOUSE", "id": "Q9DB73-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "MGIQPSPVLLASLGVGLLTLLGLALG-----TYLVRRSRRP-----QVTLQDPDEKYL-LRLLDKTTVSHNTRRFRFALPTAH----------HILGLPVGKHVYLSARIDGSLVIRPYTPVTSD-EDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKIGDMVEFRGPSGLLSYAGKGNFNIQPNKKSPPELRVAKKLGMIAGGTGITPMLQLIRAILKVPE-DPTQCFLLFANQTERDIILREDLEELQAQYPNRFKLWFTLDSPPE----------------------DWTYSKGFVTADMIQEHLPAPAED-VLLLLCGPPPMVQLACHPNLDK-------LGYSQKMRFTY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5EB81-1", "uniprot_id": "NB5R1_RAT", "id": "Q5EB81-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "MGIQPSPVLLASLGVGLFTLFGLALG-----TYLVRRSRRP-----QVTLQDPDEKYL-LRLLDKTTVSHNTRRFRFALPTAH----------HILGLPVGKHVYLSARIDGSQVIRPYTPVTSD-EDQGYVDLVIKVYLKGVHPKFSEGGKMSQYLDSLKIGDVVEFRGPSGLLSYAGKGNFNIQPNKKSPPELRVAKKLGMIAGGTGITPMLQLIRAILKVPE-DPTQCFLLFANQTEKDIILREDLEELQAQYPIRFKLWFTLDYPPE----------------------DWTYSKGFVTADMIQEHLPAPAED-VLLLLCGPPPMVQLACHPNLDK-------LGYSQKMRFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHQ9-1", "uniprot_id": "NB5R1_HUMAN", "id": "Q9UHQ9-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "MGIQTSPVLLASLGVGLVTLLGLAVG-----SYLVRRSRRP-----QVTLLDPNEKYL-LRLLDKTTVSHNTKRFRFALPTAH----------HTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSD-EDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPE-DPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLWFTLDHPPK----------------------DWAYSKGFVTADMIREHLPAPGDD-VLVLLCGPPPMVQLACHPNLDK-------LGYSQKMRFTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X2JGK6-1", "uniprot_id": "X2JGK6_DROME", "id": "X2JGK6-1", "name": "NADH-cytochrome b5 reductase", "aln": "MARIVESNFVPLAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDKYL-LPLIEKENLSHDTRRFRFGLPSKQ----------HVLGLPVGQHIHLIATIDNELIIRPYTPISSD-EDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAIKRMP--------RMGNARFVAWSYNTGHVNDDMMQQHLYPPGED-TLCLLCGPPPMVNYTCIPGLER-------LGHRAEQRFSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38626-1", "uniprot_id": "NCB5R_YEAST", "id": "P38626-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "MAIDAQKLVVVIVIVVVPLLFKFIIG----------PKTKP------VLDPKRNDFQS-FPLVEKTILTHNTSMYKFGLPHAD----------DVLGLPIGQHIVIKANINGKDITRSYTPTSLDGDTKGNFELLVKSYPT---------GNVSKMIGELKIGDSIQIKGPRGNYHYERN----------------CRSHLGMIAGGTGIAPMYQIMKAIAMDPH-DTTKVSLVFGNVHEEDILLKKELEALVAMKPSQFKIVYYLDSPDRE---------------------DWTGGVGYITKDVIKEHLPAATMDNVQILICGPPAMVASVRRSTVDLGFRRSKPLSKMEDQVFVF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VWK8-1", "uniprot_id": "Q9VWK8_DROME", "id": "Q9VWK8-1", "name": "FAD-binding FR-type domain-containing protein", "aln": "MLSYLEDLKENEDQLRDSDCCGNGCTN-----CILDNKPRPSKRVLLAGKRNVILSYTKFRLLRREALGPNGQLLLLHFAHAAEEGDGDGAVDTVLDIPPGHHVMLRVGS----LLRPYSPYWSD-----FVAKEFRILVK-----LQPEGPMSRHLQAVQPDDLLEFRGPIGQYVHEPQ----------------PAKCIYIIAQGVAIAPTLPLVRQVLDNEE-DMSRLWHLVCAHDLLHVYFREEMLEFAQFWNYRSCLYLPHQQCDSSACQEAGHCAQQCPQLRDNLRYKETAKVSRLDATELATHLNPAIPGQRVLIVAGDSSFQKNIAQIATQS-------LDVDPANIYML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: : : : : :. *.:* *::: : . : *.*:* * . .: . * ::: : :: .: : ::** * : : :** *..*:* : : : * : :. .: .: :: . : : : . : : ** .. ::.* ..: :. : ", "identical_positions": 21, "similar_positions": 70, "identity": "5.87%" }, { "cls_id": "homologset.agr.SGD:S000001306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN29-1", "uniprot_id": "SMAP2_MOUSE", "id": "Q7TN29-1", "name": "Stromal membrane-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------MTGKSVKD-----VDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDP-----------AVEGFIRDKYEKKKYMDRS--------------------------LDINVLRKEKDDKWK-RGNEPAPEKKMEPVVFEKVKMPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKT---SNALEKDLDLLASVPS--------PSS-VSRKAVGSMPTAGSAGSVP-----------------------ENLNLFPEPG--SKSEETGKK-QLSKDSILSLYGSQT-PQMPAQA--MFMAPAQMAYPTAYP-SFPGVTPPNSIMG------GMVPPPVGMVAQPGASGMLTPMAMPAGYMGGMQASMMGVPNGMMTTQQAGY------------------MASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQS---MGGGNGQAANQTLS----PQMWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XM71-1", "uniprot_id": "A0A8J8XM71_RAT", "id": "A0A8J8XM71-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTGKSVKD-----VDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDPFFDSSLISVCRAVEGFIRDKYEKKKYMDRS--------------------------LDINVLRKEKDDKWK-RGSEPAPEKKMEPVVFEKVKMPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKT---SNALEKDLDLLASVPS--------PSS-VSRKAVGSMPTAGSAGSVP-----------------------ENLNLFPEPG--SKSEETGKK-QLSKDSILSLYGSQT-PQMPAQA--MFMAPAQMAYPTAYP-SFPGVTPPNSIMG------SMMPPPVGMVAHPGASGMVTPMAMPAGYMGGMQASMAGVPSGMMTTQQAGY------------------MASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMSYGQS---MGGGNGQAANQTLS----PQMWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WU79-1", "uniprot_id": "SMAP2_HUMAN", "id": "Q8WU79-1", "name": "Stromal membrane-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------MTGKSVKD-----VDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDP-----------AVEGFIRDKYEKKKYMDRS--------------------------LDINAFRKEKDDKWK-RGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIANSKT---SNTLEKDLDLLASVPS--------PSSSGSRKVVGSMPTAGSAGSVP-----------------------ENLNLFPEPG--SKSEEIGKK-QLSKDSILSLYGSQT-PQMPTQA--MFMAPAQMAYPTAYP-SFPGVTPPNSIMG------SMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGY------------------MAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQS---MSGGNGQAANQTLS----PQMWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VZ6-1", "uniprot_id": "SMAP1_MOUSE", "id": "Q91VZ6-1", "name": "Stromal membrane-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGN-TKARLLYEANLPENFRRPQTDQ-----------AVEFFIRDKYEKKKYYDKNAIAITN---------------------------KEKEKKKDEKKREKEPEKPAKPLTTEKLPKKEEQQLEPKKSTSPKNAAEPTIDLLGLDGPAEAPVTNGNP-ATAPALSDDLDIFGPMISNPLP----AAVMPPAQGTASVPAPATLSTVT----------------------SGDLDLFTEQT--TKSEEVAKK-QLSKDSILSLYGTG--AQQSTPG--VFMGPTNIPFTSQAPTAFQGFPSMGVPVP-------AAPGLIGNMMGQ-NTGMMVGMPMHNGFMGNAQTGVMPLPQNVVGPQGG--------------------MVGQMGAPQSKFGLPQAQQPQWNLSQMNQQMAAMNLSSANASAGFGQPPSTTAGWSGSSSGQTLS----TQLWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9X6-1", "uniprot_id": "A0ABK0L9X6_RAT", "id": "A0ABK0L9X6-1", "name": "", "aln": "MRSAQSSVLPEAAALPAPPLAGSGGACGGPGEEAGHVGAASAAAAPPPVPAAAATATAAAAAAASWAESARGPSGARFPRPPGLISAVRPLARVPARRPAADMATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGN-TKARLLYEANLPENFRRPQTDQ-----------AVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLPAAVDKNKIEKEKEKKKEEKKREKEPEKPAKALTTEKLQKKEDQQPEPKKSTSPKNVAEPTVDLLGLDGPAEAPVTNGNT-TAAPPLSDDLDIFGPMISNPLP----AAVMPQAQGTASIPAAAALSTIT----------------------SGDLDLFTEQT--TKSEEGAKK-QLSKDSILSLYGTG--AQQSTPG--VFMGPTNIPFTSQAPTAFQGFPSMGVPVP-------AAPGLMGNMMGQ-NTGMMVGMPMHNGFMGNAQTGVMPLPQNVVGPQGG--------------------MVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAAMNLSSANSSAGFGQPPSTTAGWSGSSSGQTLS----TQLWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYB5-1", "uniprot_id": "SMAP1_HUMAN", "id": "Q8IYB5-1", "name": "Stromal membrane-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGN-TKARLLYEANLPENFRRPQTDQ-----------AVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPLTAEKLQKK-DQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGN--TTVPPLNDDLDIFGPMISNPLP----ATVMPPAQGTPSAPAAATLSTVT----------------------SGDLDLFTEQT--TKSEEVAKK-QLSKDSILSLYGTGTIQQQSTPG--VFMGPTNIPFTSQAPAAFQGFPSMGVPVP-------AAPGLIGNVMGQ-SPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGG--------------------MVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLS----TQLWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9Y2-1", "uniprot_id": "A0A8M9Q9Y2_DANRE", "id": "A0A8M9Q9Y2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTTRSEREKAQKLNEQHQAILSKMLREDDNKYCADCEAKG-PRWASWNLGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQSVQSMGN-TKARQLYEAHLPENFRRPQTDQ-----------AVEFFIRDKYERKKYYDKNSVNGAIKSSD--AALPSVSSPSSQ-AAEKSKLEKEREKKKEEKKREKDTDKENKPAVLEK--KREDNQIDSR--ISPKKSAEPAIDLLGLDAPTVGSASSGAGTSSAAPISDDLDIFGPMVSNPLPSNSNSSQVSSSKAAGSAQASSAGGAVAGATGTGSAAPA-----------QGDLDLFSETSGNSKAEDSAKK-PLSKDSILSLYGSSTVPQQPAQATAMFMGPSQMQFPAQPQGNFQAFPGMGGAMPPTTM-MGAVMGQGGAMMGQ-NTGMMVGMTMPNGFMGNAQPGVMGLAPGMMGPQG-------------------------MVPPQNMYAMQPGQQGQWNMAQINQQMSGMNLNGSGAPMAFGQPGAPMGGWVAPPSGQTLS----TQLWK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40529-1", "uniprot_id": "AGE2_YEAST", "id": "P40529-1", "name": "ADP-ribosylation factor GTPase-activating protein effector protein 2", "aln": "------------------------------------------------------------------------------------------------------MSTSVP----------VKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTS---------SLQNFIKNKYEYKKWIG-----------------------------------DLSSIEGLNDSTEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPP---------------------------------SHLLSTSRSNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGN--------------------------RVGEFGQRND-----LKKSILSLYSKPSAQTQSQNSFFTSTTPQP------------------------------CNTPSPFVNTGITATNNNSMNSNS-----------------------------------------------------------------------------------------------SSNISLDDNELFK-----NVWS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z7K6-1", "uniprot_id": "A1Z7K6_DROME", "id": "A1Z7K6-1", "name": "Arf-GAP domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------MSSSNAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKG-PRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTWTPEQVISLQQMGN-SRARAVYEAQLPDGFRRP--QTDT---------ALENFIRAKYEHKKYLAREWVPPSPPKVD----------------WAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFGGFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNAFSNAAISSATAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQTNQSILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQGAGGFAATGPTTSSVPSNLNQQFGNLNIGNVWQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : *: :* : .*..*.**.:: ******.:*:*:**:******.**.***:****:** *. *:: : .: * :*. *** *.: ::: ::: **: *** **: . : : . . . .::. . : * :. : . .: *.***:**.. . . * . .: : ::*.", "identical_positions": 58, "similar_positions": 70, "identity": "8.95%" }, { "cls_id": "homologset.agr.SGD:S000001307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R5-1", "uniprot_id": "PPR3C_RAT", "id": "Q5U2R5-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHS----------------PPLKSFLGPYNGLQRRHFVN-KPKPLKPCLSVKQEAK-SQKEWKSPHSQA---------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSSLKLHEEKNLVFDFPQPSSDYLSF-RDRFQKNFVCLENCSLQDRT--VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKNVYGSSDSDTFSFAIDLPRVIPTE-EKIEFCISYHAN--GRVFWDNNEAQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQVPLKTELEPTVFG--SPRLASGLFPEWQSWGRVENLASYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMB3-1", "uniprot_id": "PPR3C_MOUSE", "id": "Q7TMB3-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHS----------------PPLKSFLGPYNGFQRRNFVN-KLKPLKPCLSVKQEAK-SQSEWKSPHNQA---------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSSLKLHEEKNLVFDFPQPSTDYLSF-RDRFQKNFVCLENCSLQDRT--VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYMKNVYSSSDSDTFSFAIDLPRVIPTE-EKIEFCISYHAN--GRIFWDNNEGQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQGPPKTEIEPTVFG--SPRLASGLFPEWQSWGRVENLTSYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQK1-1", "uniprot_id": "PPR3C_HUMAN", "id": "Q9UQK1-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHS----------------PPVKSFLGPYDEFQRRHFVN-KLKPLKSCLNIKHKAK-SQNDWKCSHNQA---------KKRVVFADSKGLSLTAIHVFSDLP--EEPAWDLQFDLLDLNDISSALKHHEEKNLILDFPQPSTDYLSF-RSHFQKNFVCLENCSLQERT--VTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTE-QKIEFCISYHAN--GQVFWDNNDGQNYRIVHVQWKPDGVQ--TQMAPQDCAFHQTSPKTELESTIFG--SPRLASGLFPEWQSWGRMENLASYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTC2-1", "uniprot_id": "F1QTC2_DANRE", "id": "F1QTC2-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "--------------------------------------------------------MSSTRVLHILSP-PMPGPVMPVDVAVQLYITHS----------------PPLRNFLSSYEDYRTRNLVSNCCKPLRPCLSSRAQLEHSCRSWQNPKSKT---------KKKVVFADSKGMSLTAVHVFSTFDNKETATSELQFDLEDLEELKNTLHINSVQSRILDFLQPAADYLDF-RSHLLKNLVCLENCTLQERA--LTGTIKVRNLAYEKSVHVRITFDSWKSFEDIECTFMNNVYGCQDTDTFSFAIELPGYVPPQ-NKVEFCISFRTG--EQIYWDNNDGRNYGLISTSWQQNNKLNSSTQTKKSDEFRKKSSKKTQEKGVFKCKSSLQSNGIFPNWQSWGQIAATGPYW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P950-1", "uniprot_id": "PR3CB_DANRE", "id": "Q6P950-1", "name": "Protein phosphatase 1 regulatory subunit 3C-B", "aln": "--------------------------------------------------------MNCTRVLQILNPRPMPSPIMPVDVAMRICLAHS----------------PPLRSFLSSYEDCKSRNLVN-QYKPLRSCISSKTEDDTANITWKSPETKA---------KKKVVFADSKGMSLTAVHVFKEFE--EDLMLDLQFELSDLEDAIVGLKAEKEKNFSLGFPQPAADYLDF-RNRLKKNLVCLENCIIQERS--VTGTVKVSNVSFEKVVHVRITFDSWKSHTDIPCTYMNNVYGCEDVDTFSFSIDLPSFVAPH-EQVEFCLSYKTH--DMTYWDNNDGKNYKLVHT---ENDSSQASVIQNATTDFKAQGKRPDMEFDQFG--SPRTSSGFFPEWQSWGHIENNTPYW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C767-1", "uniprot_id": "PPR3B_MOUSE", "id": "Q8C767-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MAVDIQYSYSSMAPSLRRERFTFKISPKLS----------------KPLRPCI---------------------QLGSKDEAS-GMVAPAVQEKKV---------KKRVSFADNQGLALTMVKVFSEFD----DPLDIPFNITELLDNIVSLTTAESESFVLDFPQPSADYLDF-RNRLQTNHVCLENCVLKDKA--IAGTVKVQNLAFEKVVKIRMTFDTWKSFTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVCYECN--GQAYWDSNKGKNYRITRAELRSSP----GKIEPYN------GPDFGISFDQFG--SPRCSFGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IN01-1", "uniprot_id": "PPR3B_RAT", "id": "Q6IN01-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MAVDIEYSYSSMAPSLRRERFTFKISPKLN----------------KPLRPCI---------------------QLGSKDEAG-RMVAPTVQEKKV---------KKRVSFADNQGLALTMVKVFSEFD----DPLDIPFNITELLDNIVSLTTAESESFVLDFPQPSADYLDF-RNRLQTNHVCLENCVLKEKA--IAGTVKVQNLAFEKVVKIRMTFDTWKSFTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVCYECN--GQSYWDSNKGKNYRITRAELRSTQ----GMTEPYN------GPDFGISFDQFG--SPRCSFGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XI6-1", "uniprot_id": "PPR3B_HUMAN", "id": "Q86XI6-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "----------------------------------------------------------MMAVDIEYRYNCMAPSLRQERFAFKISPKPS----------------KPLRPCI---------------------QLSSKNEAS-GMVAPAVQEKKV---------KKRVSFADNQGLALTMVKVFSEFD----DPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDF-RNRLQADHVCLENCVLKDKA--IAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSY-ERMEFAVYYECN--GQTYWDSNRGKNYRIIRAELKSTQ----GMTKPHS------GPDLGISFDQFG--SPRCSYGLFPEWPSYLGYEKLGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803M0-1", "uniprot_id": "PPR3B_DANRE", "id": "Q803M0-1", "name": "Protein phosphatase 1 regulatory subunit 3B", "aln": "-----------------------------------------------------------MPIELA-----MSLYLSSDEFLNPRASKYS----------------RPLQPCLNQCKSS----------KLSFSSLKEQSEFN-GVSRALMIPGRA---------KKHVSFADHKGLALTVVKIFSEFD----DPIDIPDNIDNFFTSSLTVSEGK-DKLTLDFDQPSADYLKF-RQRIENDHVCLEHCMLKEKS--IMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSH-ERIEFAICYEVN--GDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYS------QSDWDIHFDRYG--SPRCSRGIFPHWPSYVGYEDIGPYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AJW4-1", "uniprot_id": "A2AJW4_MOUSE", "id": "A2AJW4-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "--------------------------------------------------------MSKGSGSAPLPSTPGSRKLVPRSLSCLSDMDR------RPCRPPG--------------CDPRLRPIIQRRSRSLPTSPERRAKAAGAPGAACGAGCNR---------QVRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLQCLVPDFSPPIETPGF-GERLARQLVCLERVTCSDLG--ISGTVRVRNVAFEKQVTVRYTFSGWRSAHEAVARWRGPAGAEGTEDIFAFGFPVPPFLLELGSQVHFALRYGVA--GAEYWDNNDGRDYSLTCRS-------------------------------------HALHMPRGECEESWIHFI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95685-1", "uniprot_id": "PPR3D_HUMAN", "id": "O95685-1", "name": "Protein phosphatase 1 regulatory subunit 3D", "aln": "--------------------------------------------------------MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQ---------KLRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADF-GERLQRQLVCLERVTCSDLG--ISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVA--GAEYWDNNDHRDYSLTCRN-------------------------------------HALHMPRGECEESWIHFI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MR9-1", "uniprot_id": "PPR3A_MOUSE", "id": "Q99MR9-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "-----------------------------------------------------------------MEPAEEPGQISKDNFLEVPNLSDS-------------------------VCEDEEVKATFKPG--FSPQPSRRGSGS-SEDMYLDTPTSA---------SRRVSFADSLGFSLVSVKEFDCWELP----------SVSTDFDLSGDVFHTDEYVLSPLFDLPSSKEKL-MEQLQVQKAVLESAEHLPGS-SMKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEY-VPNSCDGETDQFSFKISLVPPYQKEGGKVEFCIRYETS--AGTFWSNNNGTNYILVCQKKRKEPEPVKPLEEAPSRQIKGCLKVKSRSKEEPLLAPEENKFETLKFTESYIPTIICSHEDKDDLGANHPNVDDINKKHDEHNGKELDLMINQRLITS-----QDEKNTFATDTVNFTNKAEGSEKKQAYHEINTDLFMGPLSPSLSAESSLKRDFYHSRSSSPGNEYGHPHSEEIISDMGEKGPSLGDTSSDELMQLELCSKEDLDDNANPANGSGRV---CSSFDQRMACGLKNNEAG------IKKTGIQDYKYSHGDSTKLEESN---ASSRDDYAKVDNKKEKQTCLGVNENPSKNFQSVFQTQEGHMGYPKISTEGDKANNQDLTSLLSKDITANTWAVTVDPCPSTNAKRSWREVGS----------GSNLEPGTSDLSSPRNFSPLTDDHLFQADRENSDSSNPENQNMNTRHRKKWNVLETQSETSETESDIAKHTKEQAEYKDMWEKTDNSRNLKATPTEHLFTCRETECYGLSSLADHGITEKAQAVTAYIIKTTLESTPESASARGKAIIAKLPQETAGNDRPIEVKETAFDPHEGRKDDSHYSLCHGDTAGVIHDNDFERESHLDICNLRVDEMKKEKTTSTCFPQKTYDKEKHGIGSVTSIDEPSQVITGNQKATSKLDLHLGVLPTDRAIFQANADLELLQELSRRTDFNAVP-SAFNSDTASASRDSSQVYRHCSKKSVPS----YGEEKAVTNTTLQSIPTKSEYNWHPESEVLG-----HAMSKPEDVFKSSEIMKSGSGGERGGGPILQQKEGSLENSQGPMFFTNEPLENLDEASSENEGLMHSGQSQCYLGDKGLVSSASATVSTQELEAQGRESLLSISTNSKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16821-1", "uniprot_id": "PPR3A_HUMAN", "id": "Q16821-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "-----------------------------------------------------------------MEPSEVPSQISKDNFLEVPNLSDS-------------------------LCEDEEV--TFQPG--FSPQPSRRGSDS-SEDIYLDTPSSG---------TRRVSFADSFGFNLVSVKEFDCWELP----------SASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDL-MQQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEY-VPNSCDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETS--VGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKS-SKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVE-EKSGGINSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKAT-TEELFTCQETVCCELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFLLFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUF3-1", "uniprot_id": "Q9VUF3_DROME", "id": "Q9VUF3-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MISHSPPIFSHSPPVSFLADFMSGHPRQSLNYNDEPNRASRYCRPQVITLASKAMVNNASAAVQGQGPSQQKAGATPLGVGSRSGRSYLER-----MASAPLLTNQPKSCLSRKSCLHKSQNTTASSADLSPTDTDVADSASHSCICSKDSDSNGEVSRGP---KKHVIFADDEGLSLTEVRVMSEPS----NVPPYWSMKFLEQITQGLVSPHPPDQWTVDFKQPASDYLSF-RQKIERDFVSLENVIVKDEESIVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYARAYGPATCAHVVFDTFSFKITLPPSSKRLEFCICYRTN--ETEYWDNNDGKNYTISKRSPFYYNALS-------------PYDKGQNRNSSQQIRSTLTDALAKVQDQNGWHQEPHTPYW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B1R9-1", "uniprot_id": "A0A8M2B1R9_DANRE", "id": "A0A8M2B1R9-1", "name": "", "aln": "---------------------------------------------------------MSITKQYVLSSNPFPEHVMPVDLSMNAQITSFAS-------------------------RSSTDRHRFSPSSPTSSLSSSSSGGSLSSYSSGTSTLRK---------KKQVVFADSKGLNLVSIRIFIADP---SEMETEEAAQSEELVKPRTPVQNLRFKVKLGFSQPVPD-----IASLMKNFVQLESCRVKGRL--LSGTVRVFNLMLDKTVFVRITYDSWRSHRDIPCINVREPHLSFQTALFEFMEYLPSDLDPK-ELLEFFVVFCPGNVKKQYVDDNEGKQYQLHVENVAAESRLGSSESRLAPLEHRLVSSESRLSPSKHRLVTTEHRRAQSEAHRLAIESRTVTLRRRSFITPSPQCYSAWPAERVLDQQRMTNMTCRASPDHRVSKNFRSTSVTQVIC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40187-1", "uniprot_id": "PIG2_YEAST", "id": "P40187-1", "name": "GSY2-interacting protein PIG2", "aln": "-MATTTQPQNILMDEPLNLPNNSAHNNNYGNINANIRTFAGMSMHMHPARLNSLEFLHKPRRLSNVKLHRLPQDELQRNTDMNKGMYFNGK------------QVHAHHPFINSGANFNAHHQDVSKLGEEEDEISPLSHDNFQYESEENGNPSPPIYKKSGELVKSSLKRRSKSLPITPKSIFNKTG---SKSKHVNLDHVDTRLLQRSKSVHFDRVLPIKLFNENEKPIDVGKQMVQQDVLNFKHKPLTRLSALNGGSDSVPIEDLLSENNQNEYGDTWLQNPKGVFLFGTNSNNRRNK-KKKFKLSDDDSDIENDNDSDDAINRLVRQQDKDQAHLAHGLKNLLINDDDDYLETRTNSAKSGANLFIGNSKRIVGLYNKNFPILSDRNRKSLKLNIFLNLSRGRPVFLQEITLLTGFHNMVIIGKVFVKNIYFDKKIIVRYTWDAWRTFHESECVYFSNANGILPGSNMDIFKFSIDDIHNPNDKDSNISQLEFCIQYLTWGVDRSRKEYWDNNDSANYKIDVVTNETRTGPTTDVNDNYEMKHSLFRNPFH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. : . . : :: * * . . . * . . : . : ", "identical_positions": 3, "similar_positions": 18, "identity": "0.24%" }, { "cls_id": "homologset.agr.SGD:S000001309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GL93-1", "uniprot_id": "A0A8I6GL93_RAT", "id": "A0A8I6GL93-1", "name": "Solute carrier family 53 member 1", "aln": "MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDE---------------------------------DTVKRYFAKFEEKFFQTCEK------ELAKINTFYSEKLAEAQRRFATLQNELQSS---------------------------------------------------------------------------------------LDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWR---------VAHVEVAPFYICKKINQLIS------------------------ETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVG------LFFGIFIVLNITLVFAAVFKLETDR----TVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNH--VLIFELNPRNNLSHQH----------LFEIAGFLGILWCLSLLACFFAPISIIP-IYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHGYTYGVRAIVQCIPAWLRFIQCLRRYRDT-RRAFPHLVNAGKYSTTFFTVTFAALYSTHKER-GHSDTMVFFYLWVVFCIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQ-------------KAYYYCAIVEDVILRFAWTIQISITATTFKPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAP---------LNADDQ--TLLEQMMDQEDGVRNRQKSRSWKYNQSISLRRPRLPSQAKKKTTKQNMFFQRGATGKEIVLTLQSAVRKGNLKARRWPGGHCQVQDSKRPGLGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0U0-1", "uniprot_id": "S53A1_MOUSE", "id": "Q9Z0U0-1", "name": "Solute carrier family 53 member 1", "aln": "MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDE---------------------------------DTVKRYFAKFEEKFFQTCEK------ELAKINTFYSEKLAEAQRRFATLQNELQSS---------------------------------------------------------------------------------------LDVQKESSGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWR---------VIHVEVAPFYTCKKINQLIS------------------------ETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVG------LFCGIFIVLNITLVFAAVFKLETDR----TVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNH--VLIFELNPRNNLSHQH----------LFEIAGFLGILWCLSLLACFFAPISIIP-IYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHKYSYGVRAIVQCIPAWLRFIQCLRRYRDT-RRAFPHLVNAGKYSTTFFTVTFAALYSTHEEQ-NHSDTVVFFYLWVFFCIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQ-------------KAYYYCAIIEDVILRFAWTIQISITAT-FKPHVGNIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAP---------LNADDQ--TLLEQMMDQEDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTK---------------VLIEDTDDEANT----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBH6-1", "uniprot_id": "S53A1_HUMAN", "id": "Q9UBH6-1", "name": "Solute carrier family 53 member 1", "aln": "MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDE---------------------------------DTVKRYFAKFEEKFFQTCEK------ELAKINTFYSEKLAEAQRRFATLQNELQSS---------------------------------------------------------------------------------------LDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWR---------VAHVEVAPFYTCKKINQLIS------------------------ETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVG------LFCGIFIVLNITLVLAAVFKLETDR----SIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNH--VLIFELNPRSNLSHQH----------LFEIAGFLGILWCLSLLACFFAPISVIP-TYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDT-KRAFPHLVNAGKYSTTFFMVTFAALYSTHKER-GHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQ-------------KAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAP---------LNADDQ--TLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTK---------------VLIEDTDDEANT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZH4-1", "uniprot_id": "S53A1_DANRE", "id": "A8DZH4-1", "name": "Solute carrier family 53 member 1", "aln": "MKFTEHLSAHITPEWRKQYIQYEAFKEMLYSAQDQAPSIEVTDE---------------------------------DTVKRYYAKFEEKFFQTCEK------ELAKINTFYSEKLAEAQRRFATLQNELQSS---------------------------------------------------------------------------------------LDAQRESSRAAGLRHRR-TVFHLSQQERCKHRNIKDLQLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKIFETSRGADWR---------VAHVEVAPFYTCKKITQLIS------------------------ETETLVTTELEGGDRQKAMKRLRVPPLGAAQPAPAWTTFRVG------LYCGVFVALTVTVIIAGVVKLVEHFGDNTDVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNH--VLIFELNPRNNLSHQH----------LFEIAGFLGVLWCVSILSCLFAENTLIP-IHMNPLALYGFFFLFLINPLKTCYYKSRFWLLKLLFRVVTAPFHRVGFADFWLADQLNSLVVVLMDLEYMICFYSLELNWTMSEGELWIKEGE-RICYSYSYGVRAVIKCLPAWFRFVQCLRRYRDT-KRAFPHLVNAGKYSTTFFVVIFEALFKTHSG----DERFVFLYIMIACRIVNSCYTLLWDLKMDWGLFDRNAGENTLLREEIVYPQ-------------KAYYYCAIVEDVILRFAWTIPLSLEVVYDRPVISNILGTVLPPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAP---------LNADDQ--TLLEQMMDQEDGVRNRLGKKNWKRSYSMSLRRPRLSSQSKVRDTK---------------VLIEDTDDDT------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWZ2-1", "uniprot_id": "Q9VWZ2_DROME", "id": "Q9VWZ2-1", "name": "Solute carrier family 53 member 1", "aln": "MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVED---------------------------------DVLKRHFANFDENFFHYCDK------ELKKINTFYSEKLAEATRKFATLNAELKTS---------------------------------------------------------------------------------------IEE---SERSAKKSKGH------KRHAALPDRKARELKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDKLLRVDTGAKWR---------QEYVEASHFFTNKDIDNIIN------------------------ETETTVTGELEGGDRQRAMKRLRVPPLGEQQ--SPWTTFKVG------LFSGSFIVLVIVVVVSAIFHEISGE----NLKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNH--VLIFELDPRNHLSEQH----------LMELAAIFGVIWTLSMLSFLYSASLAIP-AFINPLTLTLIMVLFLANPFHVLYHDARFWLWRITGRCVSAPFFHVGFADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEA--------RDASICMEKDFIIRPIVNCLPAWFRFAQCLRRYRDS-REAFPHLVNAGKYSTTFMVVIFATLKSFHSPNYASTFDNPYTWLWIIASIVSSCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSS-------------TGFYYFAILEDLALRFIWALSFYLTEM--KIVSSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISIAP---------LDSSDQ--ALILRLMDEADGVIN-RYTKANRP-KPKKVKDPEKRSLLQTRG------------------SLPDLRIDMDSKKL-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRR2-1", "uniprot_id": "S53A1_DROME", "id": "Q9VRR2-1", "name": "Solute carrier family 53 member 1", "aln": "MKFAEHLTAHITPEWRKQYINYEEMKAMLYAAIEQSPSAELVER---------------------------------EMVTRYFAKFDEEFFHYCDK------ELAKINTFYSEKMAEATRKYGSLRSELTEA---------------------------------------------------------------------------------------LEMGHPKKLPAWKRRTP------LGKKNVPARKIQDLKLAFSEFYLGLILLQNYQNLNFTGFRKILKKHDKLLSVDYGARWR---------TDHVEAAHFYTNKDIDRLIQ------------------------ETEQAVTQDIEGGDRQRAMKRLRVPPLGEQQ--SPWTTFKVG------LFSGAFVVLFITVVIAAMFYGF-GE----NWRAGMRMFRAPFLIIECLFLWGVNVYGWRSSGVNH--VLIFELDPRNHLSEQN----------IMEVASVFGVIWACCVLSYIFCDPLGIP-QYAAPLCLYTLMAAFLLNPTKTFHHEARFWAIRILIRVIMAPFCFVNFADFWLADQLNSMVPAFLDIPFLICFFGRSPTWHKAG-------KAASHCVEYVSLLHPIVAIMPAYFRFAQCIRRYRDT-KESFPHLVNAAKYATSFFVVIFAHKYHTTTDTYPLSKENPWFYCWITAAIFSSCYAYTWDIKMDWGLFDSKAGDNRFLREEIVYSS-------------TWFYYFGIIEDLILRFSWTLSMSLIEA--GYIEGDVMMTILSPLEVFRRFIWNYFRLENEHLNNVGKFRAVRDISVAP---------MDCSDQ--TTILRMMDETDGVLNRRRGKAAGG-KSATKKNKQEQRLLLQGE------------------SIEDLCS--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4P9-1", "uniprot_id": "Q9W4P9_DROME", "id": "Q9W4P9-1", "name": "Solute carrier family 53 member 1", "aln": "MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSPLTSSD---------------------------------YEVQAYYKAFEETFLTECQS------ELTGVNNFFLEKLLEARRKHGHLKLQLLAY---------------------------------------------------------------------------------------SREP---GHTGSDSSLS----QRAERSQKKLMTTRQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWF---------VENVLDAPFTDVRLLQRMTI------------------------EVEDLYTTHLANGDRSLAMEKLRVPPLGEPT--PPSMVFRAG------IALGMLIMLLVATAISYWKRAPLED----HTPGLMRLFRGPFTWVIFNFYMAANVAGWQQAGVNH--ILIFEIDPRSHLQPAT----------FLEIACTFGILWALSMLGFLYNDLIGVSDPYVFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVGRVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAIS--WLRY--------DRVNNCFEPDVMV-PITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPYTWLFLSSCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYP--------------QAFYYFVIVENLVLRLFWAVEFTILYH--NLMTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHLAA---------LNPRQE--RMLESMMDESDGVSNRRKSN----------ERIRLGKEYF------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KT29-1", "uniprot_id": "Q7KT29_DROME", "id": "Q7KT29-1", "name": "Solute carrier family 53 member 1", "aln": "MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVEKAPSGSRPSN---------------------------------DVAIGYYRNFEELFFNSCRV------ELTKVNYFFAHKQAEAHRKLATLNYQLDRR---------------------------------------------------------------------------------------RAQQDPRGSTASRGSASS--WSRQPEGKRKFPPIKKLRLAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKNLKSEAGFAWY---------EKYVLKSTLAITLQLDRMIS------------------------TTENMYTDYLANGDRSEAMAKLRVPPLGHPT--PPVHVFSAG------LFLGLFLVSAILCFISYFAVDTSPE----FRYTFVSLFRGPISGVTFGFCLAINIKVYETVGVNQ--VLIFEVERRNAIGAMR----------ALEISSFFGYMCTLSILLYLLHKEFFIEDPIYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPFFFVNFADFWVADQWTSLVVTIVDHYYLVRFYVRY--FLDR--------SDA-FEFEPDYAV-AVIRCLPAWFRFAQSLRRFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTWAYITICIVSSIYTVFWDLLMDFGLFRVWNGENKFLRDNLVYP--------------RWFYYFVIVENTLLRCVWILEFALVHQ--ELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDIFITR---------LDPQEE--RFLESVMDNTEDLG-----------------REKLNKKYF------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40528-1", "uniprot_id": "S53A1_YEAST", "id": "P40528-1", "name": "Phosphate exporter SYG1", "aln": "MKFADHLTESAIPEWRDKYIDYKVGKKKLRRYKEKLDAEEEQSSSYRSWMPSVSVYQTAFQQREPGKSRSDGDYRSGPAFKKDYSALQREFVADFIEDWLISFQLSKCNEFYLWLLKECDKKFEVLQSQLHYYSLQKNYERDNLNRSSSNVDMSTSLYAAGLAGRSDSRVNSIDSDSRSVMYGSMPCTKEAKKPRLSLLAYCQKVLKDNRLLPSWPKRGFSLLQDLRQDASSRGRETFAFGASFLETMTTTQARNLLSNAIIEYYLYLQLVKSFRDINVTGFRKMVKKFDKTCHTRELTTFMSYARTHYTLFKHADANVQLVAQKMQQITSSQPTPTSELSSAQRDKEPITWLETQITEWFTTALTNSPKDRKHNTHKLKKLTIQYSISEQMVHRNNRSIVQMLVVGLGIGVSMTLITYTLYLGISSEETSFTHKILFPLWGGWYMVLLIAFLFLVNCFIWHRTGINYRFIMLGEIQSKNGTQFFNNDFATSKIPLKLYFLTFFIVPCAVCSMLSFALEKLTPLGFLYIGIVSFLFLCPSGLIPYWDKVVHTRKWLVVTLIRLMMSGFFPVEFGDFFLGDIICSLTYSIADIAMFFCVYSHTP---------------NNLCGSSHSRAMGVLSCLPSYWRFMQCLRRFADS-GDWFPHLLNAAKYTLGIAYNATLCAYRLSDRS------EQRRTPFIVCATLNSILTSAWDLVMDWSFAHNTTSYNWLLRDDLYLAGKKNWENGSYSFSRKLVYYFAMIWDILIRFEWIVYAIAPQT---IQQSAVTSFILALLEVLRRFVWIIFRVENEHVANVHLFRVTGDAPLPYPIAQVGDDSMDSSDLGSKAFSSLNDIPITPSHDNNPHSFAEPMPAYRGTFRRRSSVFENISRSIPWAHATDFQRPTVNTVDDRSPETDSESEVESIM--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . *** :*: * * : :: : . : ::. *. :* * *: *. :: *. :* . . * * *:** * :::.:: :* *.***: **.** : . : .: * : .. :. :: * . .. . : * : : . :: . : * * :. *:* ::: *:: :. : . : . : : : :. * * * * . : : * *.**::.* *: : * . .: : :*.: ** *.:**: *: :*:** ** : : . : **: *:.: . . :**.:: . ** :: : :* * : : *: ***.* .*:****: * **.. * :. :: : : : * . ", "identical_positions": 86, "similar_positions": 134, "identity": "9.14%" }, { "cls_id": "homologset.agr.SGD:S000001310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98195-1", "uniprot_id": "ATP9B_MOUSE", "id": "P98195-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "-------------------------------------------------------------------------------MADQIPLYPVRSAG-AAASH-------------RRAAYYSSAGPGPGADRRGRYQLEDESAHLDEMPLMMSEEGFENDESDYHTLPRARITRRKRGLEWFVCGGWKFL----CTSCCDWLINVCQRKK----ELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVVSCSQFVPALKIGYLYTYWAPLGFVLAVTIAREAIDEFRRFQRDKEMNSQLYSKLTVR---GKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQRLPALGDLFSISAYVYAQKPQLDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPNNKVGLLDLELNQLTKALFLALVVLSVVMVTLQGFAG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHVLNSYLQVHS-QPSGHNPSSAPLR--RSQSSTPKVKKSVSSRIHEAVKAIALCHNVTPVYEARA-GITGETEFAEADQD-------------FSDENRTYQASSPDEVALVRWTESVGLTLVSRDL--ASMQLKTPSGQ---VLTYCILQMFPFTSESKRMGIIVRDESTAEITFYMKGADVAMSTIVQYNDWLEEECGNMAREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRALKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHVFRPVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAILYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALLLFEDEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAEFLSLGCYVASLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLKRKLSPPSYSKLSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABB8-1", "uniprot_id": "ATP9B_RAT", "id": "D4ABB8-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "-------------------------------------------------------------------------------MADQIPLYPVRSAAAAAASH-------------RRAAYYSAVGPGPGADRRGRYQLEDESAHLDEMPLMMSEEGFENDESDYHTLPRARITRRERGLEWFVCGGWKFL----CTSCCDWLINVCQRKK----ELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVVSCSQFVPALKIGYLYTYWAPLGFVMAVTIAREAIDEFRRFQRDKEMNSQLYSKLTVR---GKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQRLPALGDLFSISAYVYAQKPQLDIHSFEGTFTRDDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNQLTKALFLALVVLSVVMVTLQGFAG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHVLNSYLQVHS-QTSGHNPSSAPLR--RSQSSTPKVKKSVSSRIHEAVKAIALCHNVTPVYEART-GITGETEFAEADQD-------------FSDENRTYQASSPDEVALVRWTESVGLTLVSRDL--ASMQLKTPSGQ---VLTYCILQMFPFTSESKRMGIIVRDEATAEITFYMKGADVAMSTIVQYNDWLEEECGNMAREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRTLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRPVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAILYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALLLFEAEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAEFLSLGCYVASLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLKRKLSPPSYSKLSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43861-1", "uniprot_id": "ATP9B_HUMAN", "id": "O43861-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "-------------------------------------------------------------------------------MADQIPLYPVRSAAAAAANR-------------KRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFL----CTSCCGWLINICRRKK----ELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVR---GKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQS-QAGGNNTGSTPLR--KAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA-GVTEETEFAEADQD-------------FSDENRTYQASSPDEVALVQWTESVGLTLVSRDL--TSMQLKTPSGQ---VLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPPSYCKLAS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4S1-1", "uniprot_id": "ATP9B_DANRE", "id": "F1Q4S1-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "-------------------------------------------------------------------------------MADGIPLNPVR------KNL-------------RKTAYYDASRP-------ARYQIEDESSNLDEMPLMMSEEAFENDESDYQTLPRARVSQRRRGLGWFLCGGWKVL----CSSCCECLVHTCRRKK----ELKARTVWLGHPEKCEEKYPKNAIKNQKYNIVTFVPGVLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRCRRDKEMNSQLYSKLTVR---GKVQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLRIGVACTQRLPALGDLFSISAYVYVQKPQLDIHSFEGNFTREDCDPPIHESLSIENTLWASTVVAS-GTVIGVVIYTGKEMRSVMNTSQSKNKVGLLDLELNRLTKALFLAQVVLSVVMVALQGFLG-PWFRNLFRFVVLFSYIIPISLRVNLDMGKSAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHIIQSYAQVSSAQSNGSSASSTPSR--KPQPPAPKVRKSVSSRIHEAVKAIALCHNVTPVYESRVNGANAEPESTEADQD-------------FSDDNRTYQASSPDEVALVRWTESVGLTLVNRDL--TSLQLKTPAGQ---ILTYYILQIFPFTSESKRMGIIVREEATGDITFYMKGADVAMASIVQYNDWLEEECGNMAREGLRTLVVAKKSLTEEQYQDFENRYNQAKLSIHDRNLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRNQDIHVFKPVSNRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHEFVELACQCPAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFKHIGRLLMVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALVLFDQEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAQLISLACYLASLAFLNEYF-----------DLSFITTRVFLWKVCVITLVSCLPLYIIKYLKRKFSPPSYSKLSS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70228-1", "uniprot_id": "ATP9A_MOUSE", "id": "O70228-1", "name": "Probable phospholipid-transporting ATPase IIA", "aln": "-------------------------------------------------------------------------------MTDSIPLQPVR--------------------------------------------------------------------------HKKRVDSRPR------------------AGCCEWLR--CCGGG----EPRPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFSQFRYFFNFYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTIIREAVEEIRCYVRDKEMNSQVYSRLTSR---GTVKVKSSNIQVGDLILVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFLGTFTREDSDPPISESLSIENTLWAGTVIAS-GTVVGVVLYTGRELRSVMNTSDPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMVFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQ---------DPPAQ--KGPTVTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNG-----VTDQAEAEKQ-------------FEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPGDQ---VLNLTILQVFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFI-----------DVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A913-1", "uniprot_id": "A0A8I6A913_RAT", "id": "A0A8I6A913-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MTDSIPLQPVR--------------------------------------------------------------------------HKKRVDSRPR------------------AGCCEWLR--CCGGG----EPRPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFSQFRYFFNFYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTIIREAVEEIRCYIRDKEMNSQIYSRLTSR---GTVKVKSSNIQVGDLILVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFLGTFTREDSDPPISESLSIENTLWAGTVIAS-GTVVGVVLYTGRELRSVMNTSDPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMVFKRLHLGTVAYGLDSMDEVQSHIFSIYTQPSQ---------DPPAQ--KGPTVTTKVRRTMSSRVHEAVKAIALCHNVTPVYECNG-----VTDQAEAEKQ-------------FEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPGDQ---ILNLTILQVFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFI-----------DVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75110-1", "uniprot_id": "ATP9A_HUMAN", "id": "O75110-1", "name": "Probable phospholipid-transporting ATPase IIA", "aln": "-------------------------------------------------------------------------------MTDNIPLQPVR--------------------------------------------------------------------------QKKRMDSRPR------------------AGCCEWLR--CCGGG----EARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTAR---GTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVAS-GTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQ---------DPPAQ--KGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNG-----VTDQAEAEKQ-------------YEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPGDQ---ILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFI-----------DVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK06-1", "uniprot_id": "Q9VK06_DROME", "id": "Q9VK06-1", "name": "Phospholipid-transporting ATPase", "aln": "MAESNVPLRDFDEESETDSETELLIRRDVPSGKQNNNNIRGRRKSSMGYSGVDAGAGSSAAGGGGSFLGNLFGSNSFGSAAGQIRYRNERSRERAKHSNGSYSSISKLAQLTHTSSGVAGAGSIGGGGGGSGSATGIKVTTGDGSVAASGGSAATGDLSNGATHSTTVIDPENGSSTVFYQHNRRKSKSRSIGNVCKLCLCSCWRKWFRPRELRARTVNLGRVN--TEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSE--DTGLSVENTLWANTVVAA-GTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGG-PWYRYMFRFVLLFSYIIPISLRVNLDMGKAFYSWQMQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTES-LERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVKTRTDAHQELNSFRRKQGHALVISGESLEVCLQYYRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSLVLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYG---ALILFVDEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYF-----------DWEFIWSYDFLWKVSLITLVSCLPLYIIKFLRKKCSPPSYLKLS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40527-1", "uniprot_id": "ATC7_YEAST", "id": "P40527-1", "name": "Phospholipid-transporting ATPase NEO1", "aln": "-------------------------MPNPPSFKSHKQNLFNSNNNQHANS-VDS--------------FDLHLDDSFDAALDSLQINNNPEPLSKHNTVG------------DRESFEMRTVDDLDNFSNHSSDSHRKSSNTDTHPLMYDNRLSQDDNFKFTNIASSPPSSSNNIFSKALSYLKVSN----TKNWSKFGSPIELSDQ----HIEREIHPDTTPVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRN-----RSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRIS--ITASAPEKSIHKFLGKVTYKDSTS---NPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKND-----------SLN--NSKVALSTTRKDMSFRVRDMILTLAICHNVTPT---------------------------------FEDDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKT----LNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESNDWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALEIYTWNKTMLVTEIATLLFYIVSVPFLGDYF-----------DLGYMTTVNYYAGLLVILLISIFPVWTAKAIYRRLHPPSYAKVQEFATP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . . ::. * : * *** .**:* :*:.**::* *:***::: ** :* :::* :* **.**: **: :**:::.: **:* *.: * :: : *..::***:* *.*.:*:*:*:::*::*: *. *::*********** :: . **.*. : * . .. *: .**.* ... * **::*****.*::*: * . *:*** : *..**.: .. * **:::*:* ::* * . . :*:::: : * . *: ::*:::*** ***:*******:.* *. : .*..* *:**::****:***: *:*:*********:* :*::*** *:: :::. : . : . . . . :: . * : : ::.:******. * ***:****:*:*::**.***:*. ** :: . .. * ***:***. :*****:***:. : * ****..*: **: ****.** *********.**:.:: * :: *.:*: .* * **: :* ::: * . ** ::*** ******:** :*:.::* *****:::*******:*** * : .::*: * * :* : *. *. :*: :: ::. .*:*.*:** : *::*. *:.::. *:*:.***:* *** :. :::: * . .*.:*********** :* *:*: *:**:*****.****.** *: .**: ***.****** *.***:**.: *: ***:* : .:.****:*::**:* *** *****.**:*: . : ******:* :*:.**:***::***:*::**. : *: :* ::*****::*::.**:**** : **: * :::: :* *: *: .* ::: * :: : : : * ::* :*:: * : :: **** *: ", "identical_positions": 391, "similar_positions": 330, "identity": "30.5%" }, { "cls_id": "homologset.agr.SGD:S000001311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJM1-1", "uniprot_id": "SR5A3_RAT", "id": "Q5RJM1-1", "name": "Polyprenal reductase", "aln": "MAGWAGAELSVLN------PLRALWLLLAAAFLLALLLQLAPARLLPSCA-LFQDLIRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVVSVLWNGSLLWFLSQSLFLGAPFPSWLWALLRTLGVTQFQALGMESKASRIQGKKLALSTFLVLVFLWVHSLRRLFECFYVSVFS-NTAIHVVQYCFGLVYYVLVGLTVLSQVPMNDKNVYALGKNLLLQARWFHILGMMMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNVTWWLVVTYVFFSQALSAFFNHRFYKSTFVSYPKHRKAFLPFLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUP4-1", "uniprot_id": "SR5A3_MOUSE", "id": "Q9WUP4-1", "name": "Polyprenal reductase", "aln": "MAGWAGFELSALN------PLRTLWLALAAAFLFALLLQLAPARLLPSCA-LFQDLLRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVISVVWNGSLLWLLSQSLFLGAPFPNWLSALLRTLGATQFQALEMESKASRMPAAELALSAFLVLVFLWVHSLRRLFECFYVSVFS-NAAIHVVQYCFGLVYYVLVGLTVLSQVPMDDKNVYVLGKNLLIQARWFHILGMVMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNLTWWLVVTYVFSSQALSAFFNHKFYRSTFVSYPKHRKAFLPFLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8P0-1", "uniprot_id": "SR5A3_HUMAN", "id": "Q9H8P0-1", "name": "Polyprenal reductase", "aln": "MAPWAEAEHSALN------PLRAVWLTLTAAFLLTLLLQLLPPGLLPGCA-IFQDLIRYGKTKCGE--PSRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQ------------GGELALSAFLVLVFLWLHSLRRLFECLYVSVFS-NVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLR-KNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIU9-1", "uniprot_id": "SR5A3_DANRE", "id": "Q5RIU9-1", "name": "Polyprenal reductase", "aln": "-------MFHILS------IVNIIWLLLALCFGAAFCLNKFSVKLPNRVEHVFQDFIRYGKTKEN---IKRASWQLVFDLSKRYFYHFYVVSVMWNGLLLLFSIRSVVMSEAFPDWIIDVLGSLTGRSRG-----------AWNEIHLSTLLLQVLLWVHTLRRLLECLFVSVFS-DGVINVVQYAFGLSYYIILGLTVLCTNDSLPQSESVS---FFNQLTWYHVVGTLLFFWASFLQHQSLSLLAKMR-TDSSGKVETLAHKMPCGGWFELVSCPHYLAELLIYAAMCVCCGCASLTWWMVVLYVLCNQALAAQLCHEYYRSKFKTYPHHRKAFIPFVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40526-1", "uniprot_id": "DFG10_YEAST", "id": "P40526-1", "name": "Polyprenal reductase", "aln": "----------MYF------DEEQLLKYTIYAYRLSFFVGICSLFIAKSCLPEFLQYGKTYRPKENSKYSSILERIKKFTVPKAYFSHFYYLATFLSLVTLYFYPK---------------------------------------------FPIVWIIFGHSLRRLYETLYVLHYTSNSRMNWSHYLVGIWFYSVLLLILNISLYKN------------SIPNTLNMNAFIIFCIASWDQYKNHVILANLV-KYS----------LPTGRLFRLVCCPHYLDEIIIYSTLLP----YEQEFYLTLVWVITSLTISALETKNYYRHKFKDNHVAPYAIIPFII", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VLP9-1", "uniprot_id": "SR5A3_DROME", "id": "Q9VLP9-1", "name": "Polyprenal reductase", "aln": "MAPPENGILEVLENLLDRYKINLLQMMFGTFIATIVFFGGLMTFVEKYLPNSIRQSFRYGKHSFKG---ETDPLVAWLEVPKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEYVLQFLDIMGGGRSHR----------KVEIDSTTACVGAFMLTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFS-LDKLTSQQILYLGVFFLAWQQQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNLLSSPHMFLEVVMYFCIADLY-MPVRIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIPFLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : : : : : . : :.* :* *** .: . . : :: : **: * :* :: . :: :* .* .* : : :: :* : *: :* :: :* * *. :...: : *:::* : : : . * . :: * :.:*: .* *::**::", "identical_positions": 27, "similar_positions": 69, "identity": "7.92%" }, { "cls_id": "homologset.agr.SGD:S000001313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52759-1", "uniprot_id": "RIDA_RAT", "id": "P52759-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "---------MSSIIRK------VISTSKAPAAIGAYSQAVLVDRTIYVSGQIGMDPSSGQLVPGGVAEEAKQALKNLGEILKAAGCDFTNVVKTTVLLADINDFGTVNEIYKTYFQGNLPARAAYQVAALPKGSRIEIEAIAVQGPFTTAGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52758-1", "uniprot_id": "RIDA_HUMAN", "id": "P52758-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "---------MSSLIRR------VISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52760-1", "uniprot_id": "RIDA_MOUSE", "id": "P52760-1", "name": "2-iminobutanoate/2-iminopropanoate deaminase", "aln": "---------MSSIIRK------VISTTKAPAAIGPYSQAVQVDRTIYISGQVGLDPSSGQLVPGGVVEEAKQALKNLGEILKAAGCDFNNVVKTTVLLADMNDFGTVNEIYKTYFQGSLPARAAYQVAALPRGSRVEIEAIAVQGPFIKA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V3W0-1", "uniprot_id": "UK114_DROME", "id": "Q9V3W0-1", "name": "RutC family protein UK114", "aln": "---------MSTIVRK------LISTANAAKPVAPYNQAVVADRTVYVSGCLGLDKDTMKLVPGGPTEQAQKALENLEAVLKAADSGVDKVIKNTVFLKDLNDFGAVNEVYKRVFNKDFPARSCFQVAKLPMDALVEIECIALTGSVETKTVQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40185-1", "uniprot_id": "MMF1_YEAST", "id": "P40185-1", "name": "Protein MMF1, mitochondrial", "aln": "MFLRNSVLRTAPVLRRGITTLTPVSTKLAPPAAASYSQAMKANNFVYVSGQIPYTPDN-KPVQGSISEKAEQVFQNVKNILAESNSSLDNIVKVNVFLADMKNFAEFNSVYAKHFHTHKPARSCVGVASLPLNVDLEMEVIAVEKN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::*: :** *. . ..*.**: .:. :*:** : .. : * *. *:*::.::*: :* :.... :::* .*:* *:::* .*.:* *: ***:. ** ** . :*:* :*: ", "identical_positions": 34, "similar_positions": 54, "identity": "22.22%" }, { "cls_id": "homologset.agr.SGD:S000001314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1R9-1", "uniprot_id": "RL34_MOUSE", "id": "Q9D1R9-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTQKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49207-1", "uniprot_id": "RL34_HUMAN", "id": "P49207-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11250-1", "uniprot_id": "RL34_RAT", "id": "P11250-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVLPGRLRGVVAVRPKVLMRLSKTKKHVQQGLWWLHVRQVCPDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZWJ7-1", "uniprot_id": "RL34_DANRE", "id": "Q7ZWJ7-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKTGKSPKSACGICPGRLRGIRAVRPQVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQTQKSK---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHE5-1", "uniprot_id": "Q9VHE5_DROME", "id": "Q9VHE5-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTLRRRLSYNTRSNKRRIVRTPGGRLVYQYVKKNPTVPR--CGQCKEKLKGITPSRPSERPRMSKRLKTVSRTYGGVLCHSCLRERIVRAFLIEEQKIVK-ALKSQREALVKPVKAPKAKPEPKKKPAAGAKGTKAGAGKVTKGGAGAKGAAGKKPGQKPAAG---KPRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBH8-1", "uniprot_id": "Q9VBH8_DROME", "id": "Q9VBH8-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTLRRRLSYNTRSNKRRIVRTPGGRLVYQYVKKNPTVPR--CGQCKEKLHGITPSRPSERPRMSKRLKTVSRTYGGVLCHSCLRERIVRAFLIEEQKIVK-ALKSQREALVKPVKKVVEK-KPVKAAAKKPAGKAAGK-------PGAK-VAGKKPAPKGAPKGVVKSKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40525-1", "uniprot_id": "RL34B_YEAST", "id": "P40525-1", "name": "Large ribosomal subunit protein eL34B", "aln": "MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPK--CGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIVRAFLIEEQKIVKKVVKEQTEAAKKSEKKSKK---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:* *** .*** *** :: :***. : :.** . *: ** *:*: . ** :** * *.: . :** *********** .:* * :: ", "identical_positions": 44, "similar_positions": 24, "identity": "25.29%" }, { "cls_id": "homologset.agr.SGD:S000001323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62376-1", "uniprot_id": "RU17_MOUSE", "id": "Q62376-1", "name": "U1 small nuclear ribonucleoprotein 70 kDa", "aln": "---MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIR-EFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQG-DAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA---DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRD---RDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRER----ARRERERKEELRGGGGGGGGGSGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDR--EHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G5W4-1", "uniprot_id": "A0A8I6G5W4_RAT", "id": "A0A8I6G5W4-1", "name": "U1 small nuclear ribonucleoprotein 70 kDa", "aln": "---MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIR-EFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQG-DAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA---DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRD---RDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRER----ARRERERKEELR------------GGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDR--EHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08621-1", "uniprot_id": "RU17_HUMAN", "id": "P08621-1", "name": "U1 small nuclear ribonucleoprotein 70 kDa", "aln": "---MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIR-EFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQG-DAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA---DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRD---RDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRER----ARRERERKEELR------------GGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGG-GQDNGLEGLGNDSRDMYMESEGGDGYLAPENGYLMEAAPE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17133-1", "uniprot_id": "RU17_DROME", "id": "P17133-1", "name": "U1 small nuclear ribonucleoprotein 70 kDa", "aln": "---MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKS-RGYLGVAKFMA-DFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATE-DPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHA---DGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLE-REREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRG-AVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDR----------DREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00916-1", "uniprot_id": "RU17_YEAST", "id": "Q00916-1", "name": "U1 small nuclear ribonucleoprotein 70 kDa homolog", "aln": "MNYNLSKYPDDVSRLFKPRPPLSYKRPTDYPYAKRQTNPNITGVANLLSTSLKHYMEEFPEGSPNNHLQRYEDIKLSKIKN-AQLLDRRLQNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGG--RGYSNRDSRLPGRFASASTSNPAERNYAPRLPRR------------ETSSSAYSADRYGSSTLDARYR----GNRPLLSAATPTAAVTSVYKSRNSRTRES-------------------------------------QPAPKEAPDY-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :: ** .* *:.: * : ::: *:* : .::. : :.: :* * : .* :. :: .: *:* : *.::*:*:.*: ** * :*:: * :* *::* :: .: : *.:***** ::. . : *:*. * :*..: :**:**.**** : ********** ** : : : .** . : . : * :* * : : * * .. : : : * : :** . ", "identical_positions": 65, "similar_positions": 86, "identity": "13.86%" }, { "cls_id": "homologset.agr.SGD:S000001324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLF8-1", "uniprot_id": "ARPC5_RAT", "id": "Q4KLF8-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "MSKNTVSSARFRKVDVDEYD-ENKFVDEED--------GGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNG-VDLLMKYIYKGFESPS-DNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15511-1", "uniprot_id": "ARPC5_HUMAN", "id": "O15511-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "MSKNTVSSARFRKVDVDEYD-ENKFVDEED--------GGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNG-VDLLMKYIYKGFESPS-DNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPW4-1", "uniprot_id": "ARPC5_MOUSE", "id": "Q9CPW4-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "MSKNTVSSARFRKVDVDEYD-ENKFVDEED--------GGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNG-VDLLMKYIYKGFESPS-DNSSAVLLQWHEKALAAGGVGSIVRVLTARKTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D898-1", "uniprot_id": "ARP5L_MOUSE", "id": "Q9D898-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSS-RFRRVDIDEFD-ENKFVDEHEEA-----AAAAGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNG-IDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L108-1", "uniprot_id": "ARP5L_RAT", "id": "A1L108-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSS-RFRRVDIDEFD-ENKFVDEHEEA-----AAASGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNG-IDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPX5-1", "uniprot_id": "ARP5L_HUMAN", "id": "Q9BPX5-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSS-RFRRVDIDEFD-ENKFVDEQEEA-----AAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNG-VDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQD8-1", "uniprot_id": "Q9VQD8_DROME", "id": "Q9VQD8-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "MAKNTSSN-AFRKIDVDQYN-EDNFREDDG--------VESAAAGPDESEITTLLTQGKSVEALLSALQNAPLRCKNQNVKDHALNITLRVLLSIKSTQMDQAIDTLDQNDLIDVLMKYIYRGFEIPS-EGSSGHLLQWHEKAFAKGGVGCIVRVLSDTNRA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40518-1", "uniprot_id": "ARPC5_YEAST", "id": "P40518-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "------MEADWRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQLLTTDPPYSADAP-TKEQYFKSVLEALTQVRQADIGNVIKNLSDSQ-RDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*::*:* :: *. * :: .*. *. :.* . .*:: .*..* ..: :: :.:..*. . *:*:**:*:*:. * : ... ** * *: .*: *:: :: . .", "identical_positions": 25, "similar_positions": 53, "identity": "15.43%" }, { "cls_id": "homologset.agr.SGD:S000001325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDH4-1", "uniprot_id": "RNB3L_MOUSE", "id": "Q6PDH4-1", "name": "Ran-binding protein 3-like", "aln": "-------------MSTTQRKDDSHLFTSSCTRQLQVQEDRQQQEKYVIAQPIFVFEKG------------------------------------------------------------------------EHNFKRPAEDSLEETAEPEFTGFLRKRVRSSSVTLH---------------------------TTDPQSQG------------------------------VATLSQTRLRSSSFTDVPTFPPCRPVRKNNVFMTSRLLQRSDD------MNNVEQGPPMRSSEQVLRPAVLQPSQTQSCQKAGTTFGPG----------------------ALKSYKTKEKAEHEISEVGSSSSLLSENLPNARSSIQLSTDP-CISEAPSGCQPKEDKCSFTSCSSDFVFGENMVERVLGTQKLTQPPLQNLSYAKEKTFKSVLKFPN--AVSNSDSIENISLVESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATESWSERGQGILRLNDTAGRECGTLQSRLIMRNQGSLRLVLNSRLWAQMKIQR------ASQKNLRITATDLEDDGIKIFLIQASAKDTGFLYAAIHHRLVALRS-----------LAKQGDGGPAESQSDTALPQLNGESCD--EDEDEIAQVTKNGSDPSRWSHRQSIVCS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCF1-1", "uniprot_id": "A0A8I5YCF1_RAT", "id": "A0A8I5YCF1-1", "name": "Ran-binding protein 3-like", "aln": "-------------MSTTPRKDDSHLFTSVRPCQLKVQEEQQPQEKYVIAQPIFVFEKG------------------------------------------------------------------------EHNFKRPAEDSLDEAAELEFTGFLRKRVRSSSVTLR---------------------------TTDSQSLGDLNCSPNNRVPVELDKRPSSLMTCICNLLLVAALSQARLRSSSFTDVPTFPPSRPVRKNNVFMTSRLLQRNDD------MNNVGQGPPVRPSDHVLRPAVLQPSRTQSCQKGGTTLGPG----------------------ASKTCETKENTEHKISEADS--SLLSENLSNARSSVQMSTDP-CISEAPSGGHPKEDECSFTSCSSDFVFGENMVERVLGTQKLTQHPLQNLSYAKEKSFKSLLKFPN--VASNSEPIKNISLIESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATQSWSERGQGVLRLNDTAGSECGTLQSRLIMRNQGSLRLVLNSRLWAQMRTQR------ASHKSLRITATDLEDDRIKIFLIQASAKDIGFLYAAIHHRLVALRS-----------LGQQGDGGPAGKQADTVLPQVSGGSCD--EDEDDITQVTKTGPDPSRWNHRQSIVCL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VV4-1", "uniprot_id": "RNB3L_HUMAN", "id": "Q86VV4-1", "name": "Ran-binding protein 3-like", "aln": "-------------MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKG------------------------------------------------------------------------EQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFH---------------------------ITDSQSQG-------------------------------------------------------VRKNNVFMTSALVQSSVD------IKSAEQGP-VKHSKHVIRPAILQLPQARSCAKVRKTFGHK----------------------ALESCKTKEKTNNKISEGNS--YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR------ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQS-----------FNKQRDVNQAESLSETAQ-QLNCESCD--ENEDDFIQVTKNGSDPSSWTHRQSVACS------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CT10-1", "uniprot_id": "RANB3_MOUSE", "id": "Q9CT10-1", "name": "Ran-binding protein 3", "aln": "-------------------------------MADLANE-----EKPAVAPSVFVFQKDKGQK--------------------------------------------------------------------RSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLT-----------------------------HSEEKSSG--------------------------FRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQT-VPSSGTNGVSMPADCTGPATSVSPENLTQRSPSESAEETHTLEEKVPQKTPHG-TSEEGHCEE-EQAAPQAFVFGQNLRDRVKLMNENASVADVDSAAHPSSETPSATNYFLQYISSSADNATHSA--DNST-KFVFGQNMSERVLSPPKLNEANSDTSRET-------THAQSGSESSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDK------ASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRS-----------RAEQEQEAKAPPPEPGATRATEEEDS---DEDAVLAPSGVTGAGTGDEGDGQAPGST------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVI9-1", "uniprot_id": "A0A8I5ZVI9_RAT", "id": "A0A8I5ZVI9-1", "name": "Ran-binding protein 3", "aln": "MVLMGVSTAMKALLVQVLSTVCLWAARQGTAAEVLFNEYLWKPEKPAVAPSVFVFQKDKGQKSSTEHRDLPESGEEPQGEAEAPRPDAGYPESTGEHALDPSAPASASTSSPPLPAPAAQPP-CVQELSGRSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLT-----------------------------HSEEKSSG--------------------------FRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQT-VPSSGTNGVSMPADCTGPATSASPENLTQRSPSESAEGTHTFEEKVPQKTPSG-GSEETHCEE-EQVAPQAFVFGQNLRDRVKLMNEKANVADVDSAAHPGSETPTATNYFLQYISSSADNSTHSA--DTST-KFVFGQNMSERVLSPPKLNEANSDTSRET-------THAQSGSESSSQEAVPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASADDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDK------ASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRS-----------RAEQEQEAKAPPPEPGATRAAEEEDS---DEDAVLAPSGVTGAGAGDDGDGQATGST------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6Z4-1", "uniprot_id": "RANB3_HUMAN", "id": "Q9H6Z4-1", "name": "Ran-binding protein 3", "aln": "-------------------------------MADLANE-----EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFP------------------------PSQSEERSSG--------------------------FRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQT-VPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSA--DASSNKFVFGQNMSERVLSPPKLNEVSSDANREN-------AAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDK------ASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRS-----------RVEQEQEAKMPAPEPGAAPSNEEDDS---DDDDVLAPSGATAAGAGDEGDGQTTGST------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GPP8-1", "uniprot_id": "A0AC58GPP8_DANRE", "id": "A0AC58GPP8-1", "name": "Ran-binding protein 3-like", "aln": "----------------------------------MADDN----DKPAVAPPVFVFQKDKAQK--------------------------------------------------------------------RSAEESSTEDGEDSDKEDGSYSPAAKRGRTSPFTQFPPTHSVSKNNVFMPSSLCQSPTENSDSEPEEKTVG--------------------------FRLKPPTLIHGQAPSAGVPSPKPKEAQRSILRPPVLQPPPVKSPPQNNISSNSSNGVKKLSDGGTECEGHSEASAAGTQENSESLDKSTLEPETDDK-------PEQHGAQ----IDASFVFGENMRDRAKVGNS---LDSSQKADGLQTENSGETNYFLQCITPSAQ-KPDSS--NANSVKFVFGQNMLDRVVALPKFTTDAPGGSRESGSEMGLFSQLSSTQEQTVEKSDNMKESLEESAARHEAHKPQKCLLERVEVRTGEESESNVLQMQCKLFVFEMLSQSWVERGCGVLRLNDKTSTDDGTLQSRLVMRTQGSLRVILNTKLWPQMQVDK------ASEKSLRITAIDTEEQGVKVFLISSSSKDAAQLFAALHHRILALRS-----------ISGQESDGQPALPDGEIIRFSDDDESRTPPTAATPAPGELPEQRPAACLAHLFISADITVYIKT-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCI7-1", "uniprot_id": "Q9VCI7_DROME", "id": "Q9VCI7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MSENNEASVETNCFRGGFTLKASRLGGAVLRP----------------------------AVLANSSG----------------------------------------SNNSSTSPSAGEDSALLNNPFLRESKDDDDDEE-VVATGSAAAESTGDKEDDDVDERPDPLTKLRSNGIERSSMFAAAKNNMPN----------------VQSSGFVFGQNVHERVVAPNAEQVTAEPDADTAASSVS-------------AQEAASSSTAATSSSAPLLFSSVIQNAAQTTETSEAAASSSICSS---------------SSNNKESAEAKSLTDVAREYEESRAQKRKYEEVETFTGEEDEINIIDVSCKLFAFLNS--NWEERGRGSLRLNDAKDLRG---DSRVVFRTSGNLRLLLNTKVWAAMVAER------ASQKSLRLTAIDNSG-VVKIFLAMGRPADIAQLHKALSERIAKRKVSHPEECSVEEAKNGVASEAAASLQPESTTHDDEDEDAAPGPSGAISAEADSYGPSPKKVIVQPDSSADVPVPPVEEGDEDAEAEAKESTDQN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40517-1", "uniprot_id": "YRB2_YEAST", "id": "P40517-1", "name": "Ran-specific GTPase-activating protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------MSETNGGNAARENSEVKQTAVENPIDKLDGTPKRPR------------------------------EKDQD--------------------------------------------------------------EQAEETSDKSE------APNKNDEEKKEEGKKDQEPSHKKIKVDDGKTVESGIVEDDK---------------------KEDKFVFGAASKFGTGFGVAKKDTKDGDATTSTESLP-------------ASDSKTKKPFAFGSGLSFGSGFNILKNKTENNSESEKKATDVDKD--------------------KVHSGSEQLANASEDTKDKPKPLKLQKQEVKSGEESEECIYQVNAKLYQLSNIKEGWKERGVGIIKINKSK---DDVEKTRIVMRSRGILKVILNIQLVKGFTVQKGFTGSLQSEKFIRLLAVDDNGDPAQYAIKTGKKETTDELYNIIVKSVPK-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . . . . . : : . . . : . : . . . * . :. :. :*** * : .:..*:: : .* *** * :::*. .:*:::*. * *:::** :: : :: ..* :*: * * . : : . *. : . : ", "identical_positions": 23, "similar_positions": 64, "identity": "3.25%" }, { "cls_id": "homologset.agr.SGD:S000001326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D853-1", "uniprot_id": "EFMT2_MOUSE", "id": "Q9D853-1", "name": "EEF1A lysine methyltransferase 2", "aln": "MNADAEGHSGAVVPAQSPEGSSAADDFVPSALGTREHWDAVYERELRTFQEYG-DTGEIWFGE-ESMNRLIRWMQK----HKIPLDAS-VLDIGTGNGVFLVELVKHGFS-NITGIDYSPSAIKLSASILEKEGLSN-INLKVEDFLNPSTKLSGFHVCVDKGTYDAISLN-------PDNAIEKRKQYVMSLSRVLE-VKGFFLITSCN------------WTKAELLDAFSEG-------FELFEELPTPKFSFGGRSGNT---VAALVFQKRGTSLDKIS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JPI9-2", "uniprot_id": "EFMT2_HUMAN", "id": "Q5JPI9-2", "name": "EEF1A lysine methyltransferase 2", "aln": "MSSGADGGGGAAVAARSDKGSPGEDGFVPSALGTREHWDAVYERELQTFREYG-DTGEIWFGE-ESMNRLIRWMQK----HKIPLDAS-VLDIGTGNGVFLVELAKFGFS-NITGIDYSPSAIQLSGSIIEKEGLSN-IKLKVEDFLNLSTQLSGFHICIDKGTFDAISLN-------PDNAIEKRKQYVKSLSRVLK-VKGFFLITSCN------------WTKEELLNEFSEG-------FELLEELPTPKFSFGGRSGNS---VAALVFQKM------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5D013-1", "uniprot_id": "EFMT2_DANRE", "id": "Q5D013-1", "name": "EEF1A lysine methyltransferase 2", "aln": "MNSSVSTHGTGDCPVNCTK----SEDFAPSKLGTKEYWDGAYKRELQTYKDIG-DVGEIWFGE-ESMHRVIRWMEA----QNISENAA-ILDIGTGNGMFLVELARHGFS-NLTGIDYSKAALELTTNILVEEGLKN-INIQVEDFLNPSTELKGFDVCIDKGTFDAISLN-------PEDREEAKKHYVTSLRAVMR-PNGFFIITSCN------------WTKEQLLEIFKPG-------FELVRELPTPNFQFGGVTGNS---VTALVFKQTD-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQJ8-1", "uniprot_id": "Q9VQJ8_DROME", "id": "Q9VQJ8-1", "name": "Protein-lysine N-methyltransferase CG9643", "aln": "MDSELNG----------------------SELGTKEFWESSYNREIRNYKSHG-DVGEIWFDE-SAQWRTIDWLLNE---EKIDKEASRVLDLGCGNGMFLVGLANEGFTGDLTGVDYSPKAVELAQNIAEDNKLS--ITYKVADLTQPQNELGQFDVVHDKGTYDAVSLC-------PDNAKEKRALYLDTVEKLLRTADSLFVITSCN------------WTEDELVDSFAEK-------FVKYYTIPTPTFKFGGKVGNV---VTSIVFKRKKE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40516-1", "uniprot_id": "EFM4_YEAST", "id": "P40516-1", "name": "Protein-lysine N-methyltransferase EFM4", "aln": "MQGTADLS--------------------TSKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS-VVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFSGDWKPGKYDIVLDKGTLDAISLSGMK----INGKLDVVDVYAGVVERILK-KDGIFLITSCN------------FTQDELVKIIETDN------LKMWKTIKYPVFQFGGVQGAT---ICSVAFVKQN-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D4ADU7-1", "uniprot_id": "D4ADU7_RAT", "id": "D4ADU7-1", "name": "EEF1A lysine methyltransferase 4", "aln": "MASPRTPVS-------------------PPELPERNLQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCP---------EDRILVLGCGNSALSYELFLGGFP-NVTSVDYSP--VVVAAMQVRYAHVPS-LRWETMDIRALDFPSGSFDVVLEKGTLDALLAGEPDPWNVSSEGVHTVDQVLSEVSRVLVPGGRFISMTPAGPHFRIRHYAQPCYDWSLRHTTYSSGFHFHFYVMHKGRELTVSQLALGAQILSPPSPPAPPCFLQDSDNEDFLSAIQL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . * :: . :: . **.: : : :: :* **. : * * .:..:*** : :: : : : *: . :.: :*** **: . . : :: :: :*... : : : . : :*. . * : ", "identical_positions": 21, "similar_positions": 55, "identity": "7.32%" }, { "cls_id": "homologset.agr.SGD:S000001327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84817-1", "uniprot_id": "FIS1_RAT", "id": "P84817-1", "name": "Mitochondrial fission 1 protein", "aln": "---------MEAVLNELVSVEDLKNFERKFQSE-QAAGSVSKSTQFEYAWCLVRSKYNDDIRRGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGL-IGLAVSKSKS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ92-1", "uniprot_id": "FIS1_MOUSE", "id": "Q9CQ92-1", "name": "Mitochondrial fission 1 protein", "aln": "---------MEAVLNELVSVEDLKNFERKFQSE-QAAGSVSKSTQFEYAWCLVRSKYNEDIRRGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGL-IGLAVSKSKS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3D6-1", "uniprot_id": "FIS1_HUMAN", "id": "Q9Y3D6-1", "name": "Mitochondrial fission 1 protein", "aln": "---------MEAVLNELVSVEDLLKFEKKFQSE-KAAGSVSKSTQFEYAWCLVRSKYNDDIRKGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGL-IGLAVSKSKS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZT2-1", "uniprot_id": "FIS1_DROME", "id": "B7YZT2-1", "name": "Mitochondrial fission 1 protein", "aln": "---------MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEELARTHP-DGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIES-NDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARNKQKREK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40515-1", "uniprot_id": "FIS1_YEAST", "id": "P40515-1", "name": "Mitochondrial fission 1 protein", "aln": "MTKVDFWPTLKDAYEPLYP-QQLEILRQQVVSE--GGPTATIQSRFNYAWGLIKSTDVNDERLGVKILTDIYKEAE-SRRRECLYYLTIGCYKLGEYSMAKRYVDTLFEHERNNKQVGALKSMVEDKIQKETLKGVVVAGGVLAGAVAVASF---FLRNKRR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : . ::* :.:: * .: .::*:**: *::* :* * *: :* :: . :*: ::**:.* :: ** . :* ::: * *.*. *: :.. :.*: *:.:.** .: .: : .* : ", "identical_positions": 27, "similar_positions": 59, "identity": "16.36%" }, { "cls_id": "homologset.agr.SGD:S000001328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Q5-1", "uniprot_id": "Q5U2Q5_RAT", "id": "Q5U2Q5-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLEIVMAHKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP-----EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPEDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------LKDKEKAL--KEEEEKER----------------------------------------------NTAAMVCSLENREECLMCGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07742-1", "uniprot_id": "RIR1_MOUSE", "id": "P07742-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP-----EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------LKDKEKAL--KEEEEKER----------------------------------------------NTAAMVCSLENREECLMCGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23921-1", "uniprot_id": "RIR1_HUMAN", "id": "P23921-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTS-----EHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------LKDKEKVS--KEEEEKER----------------------------------------------NTAAMVCSLENRDECLMCGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79732-1", "uniprot_id": "RIR1_DANRE", "id": "P79732-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGGQEGVMFDKITSRIQKLCYGLNSDFVDPTQITMKVIQGLYSGVTTVELDTLAAETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKETLDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMYLEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLDECWGEEFEKLYAKYEQEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNLGTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYVTS-----ERTFDFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFESTEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDWAALKEKIANDGVRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAYIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLNKEK-------------------------LKETQKTTSSEDEETKER----------------------------------------------NKAAMVCSLENRHECLMCGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48591-1", "uniprot_id": "RIR1_DROME", "id": "P48591-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTP-----EKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSM------------------NGQNGTAEGSPQKYEEDRER----------------------------------------------KMADMVCSLENKDACMSCGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21672-1", "uniprot_id": "RIR3_YEAST", "id": "P21672-1", "name": "Ribonucleoside-diphosphate reductase large chain 2", "aln": "-----------MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGRG-KTIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVSEDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDWETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVYVPKGTKFSEQKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDSVAPAVPTETIKEDSDEKKCDIYNEKVIACTAPTPEACESCSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::****** :* * ******** :*.*.*: : :*.. :* ::*.*:*.**** ***.**** .* * ***** ******:*****:*.* **.*:***:: :* ..:: *:::. ::* : ***:*:***** *.:************: **::******::***::*** .** :.::****:* ::********* *.* :**:*****::*. ******:.::::**:***:***:*: : **:.* *.****.****:**:** **.********.*******::***** *:*:*::::*. **** ****** ************: : *:*:.* .***.: **:***:** **::** :.:***.**:**:::*.***.*:*::**:****:*:**:****.**** *****:: ** *******:** :* :::*::* .::*::.:***::** ****: ** ** :***:.:*:**:**: :::* *:** ** ** *******:.:**:**:** * *.*: *.*.******:***: * .:*** *::.* *:**** :********:**:* **.:** *:*:* *********:** :**:**.: .:*.:.**: :*: .**** : :* .:::********* *: ::***:*. :****:*:*:.: *. **:**:***.** ***********:..: .****:::: . .. .*: : :.*: . . * *..", "identical_positions": 430, "similar_positions": 232, "identity": "48.81%" }, { "cls_id": "homologset.agr.SGD:S000001330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62825-1", "uniprot_id": "EXOC3_RAT", "id": "Q62825-1", "name": "Exocyst complex component 3", "aln": "-------------------------------------------------------------------------------------------------------------------MCKDSACFSTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAA-IQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWR----------------------------QSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPE----IVRETQDLIEQGALLQAHRKLMDLECSRDGLMCEQYRMDSG-----NKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVP----------PGRPKNWKEKMFA-VLDRTVTTRIEGTQADTRESDKM--WLVRHLEIIRKYVLDDLVIAKNLLVQCFPPHYDIFKNLLSMYHQALSIRMQDLAS-EDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVNALEPLLSPNVVSELLDTYMSTLTSNIIAWLRKALETDKKDWSK-ETEPEADQDGYYQTTLPAIVFQ-----------------MFEQNLQVAA-----QISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYKEEHLRNR----------QHPHCYVQYMVAIINNCQTFKESIISLKRKYLKPETEESLCQSQPSMDGILD---AIAKEGCSSLLEEVFLDLEQHLNELMTKKWML-GSNAVDIICVTVEDYFNDFA-KIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSL--LYLEVSTLVSKYPDIRDDHIGALLALRGDASR---DMKQTIMETLE-QGPMQASPNYVPIFQEIVVPSLNVAKLLK------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KAR6-1", "uniprot_id": "EXOC3_MOUSE", "id": "Q6KAR6-1", "name": "Exocyst complex component 3", "aln": "-------------------------------------------------------------------------------------------------------------------MCKDSACFLTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAA-IQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWR----------------------------QSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPE----IVRETQDLIEQGALLQAHRKLMDLECSRDGLMCEQYRMDSG-----NKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVP----------PGRPKNWKEKMFA-ILDRTVTTRIEGTQADTRESDKM--WLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLSMYHQALSTRMQDLAS-EDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVSALEPLLSPNIVSELLDTYMSTLTSNIIAWLRKALETDKKDWSK-ETEPEADQDGYYQTTLPAIVFQ-----------------MFEQNLQVAA-----QISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR----------QHPHCYVQYMIAIINNCQTFKESIISLKRKYLKTEAEEGLCLSQPSMDGILD---AIAKEGCSSLLEEVFLDLEQHLNELMTKKWLL-GSNAVDIICVTVEDYFNDFA-KIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSL--LYLEVSTLVSKYPDIRDDHIGALLALRGDASR---DMKQTIMETLE-QGPMQASPNYVPIFKEIVVPSLNVAKLLK------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60645-1", "uniprot_id": "EXOC3_HUMAN", "id": "O60645-1", "name": "Exocyst complex component 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAA-IQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWR----------------------------QSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPE----IVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSG-----NTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVP----------PGRPKNWKEKMFT-ILERTVTTRIEGTQADTRESDKM--WLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLAS-EDLEANEIVSLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVK-ETEPEADQDGYYQTTLPAIVFQ-----------------MFEQNLQVAA-----QISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR----------QHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILD---AIAKEGCSGLLEEVFLDLEQHLNELMTKKWLL-GSNAVDIICVTVEDYFNDFA-KIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVAVAEVIKLTDPSL--LYLEVSTLVSKYPDIRDDHIGALLAVRGDASR---DMKQTIMETLE-QGPAQASPSYVPLFKDIVVPSLNVAKLLK------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8K2-1", "uniprot_id": "EXOC3_DROME", "id": "Q9V8K2-1", "name": "Exocyst complex component 3", "aln": "---------------------------------------------------------------------------------------------------------------------------MDLQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTG-MQGQLDGVRVGLKQLETCMQDVREVRRRMDEVERLLR----------------------------GVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDA----SVQKTMALIEDDKLLNAHQCLADLENSRDDLLYELHKQPKQ-----HASDKITLKRHFEKVDTVSQELEKKLRLILSRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLP----------PGRPKAWRRMIMD-VLQQSVITRIEGSKLEERADNKM--WLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVR-SGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVHR-QIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWFT-ETVPDQDEE-YYHTSAPVIIFQ-----------------MIDQHLQVTN-----TIHQELTFKALVMSIQQVEIFGQTYLKNVIELKEHHFRNR----------DQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFER-LLATFQ---RIRAHAASYLLEEAFLDMECHFNDLFTAKWLA-SNIAVDTICVTLDDYFQDYN-HLRPNNFEMVINEAQKLLAKRYIRALLSKRLS-KPRAECDAITRKIKTEAKRFKLFFEKIAPKISLS-DSPLDLISTLSALLS-SDIEL--LVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAA--EVREKVQDAMKSKKAMVSIAKQDCIFKEIVFS----DKLW-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BI71-1", "uniprot_id": "EX3L1_MOUSE", "id": "Q8BI71-1", "name": "Exocyst complex component 3-like protein", "aln": "-----------------------------------------------------------------------------------------------------MDSKIQP--TLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYRPEQLTRLGQYRSREIQRNYSLEARIKSV-VQSYLEGVQTGVWQLTRALEAVQGTREALSQAHHLLK----------------------------GLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPA----TVAHTQTLIDSERLLEAYVSLRELEQLKEETLAPLGG---------------LELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDPALLVAAIRVAEVE--------TER-TILGQ-------------APRDWRQRCLR-ALQEGLERVHFASPVLPEPG-----ALAGWLEALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADTFALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLTSENIEQLEAAFVAQVQVSVAQWLKKALDGEVAEWSG-EQEPPTDPSGFYHSPMPAIVLQ-----------------ILAENIQVTN-----LISDSLHRRAHNMAVSELGAFLRSFSDALIRFSRDHLRGD----------AVAPHYVPYLLSAFNHQSALRSSVSVLLP-------DGEASGVLAPVEAALD---DVQRRICRLVLEVLQVELQPLFSALPSRRWLL-SSELLDGVCEQTSHFCQDFW-RVRKPGVQLLLAEAERTVVLQYLRALMQGRLVCRGTDERSQAAERLRQDAAQLKELFLGLGLEESA---HCAPVLLALRELLNLHDPTL--LGLEVAGLRQQFPDVSEDHVSALLDLRGDVSR---EHRQAALSSLQAGPPPSPSTGRRALFSLVPTPTPSLSSCLPSGPCS-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VI1-1", "uniprot_id": "EX3L1_HUMAN", "id": "Q86VI1-1", "name": "Exocyst complex component 3-like protein", "aln": "-----------------------------------------------------------------------------------------------------MDSAAKD--EMQP-ALSPGPEWPEQERAEQLARGAALKWASGIFYRPEQLARLGQYRSREVQRTCSLESRLKSV-MQSYLEGVQTGVWQLAQAIEVVQGTREALSQARGLLQ----------------------------GMSQALQTLEPLRERVAQHKQLQALSHLLPRLRAVPA----AVSHTQTLIDGQQFLEAYVSLRELEQLREDTWAPLGG---------------LELPVFQGLDLLFEALGQAVEAAAGAAGKLAREDPALLVAAVRVAEVE--------TGRTTPLGQ-------------VPRDWRQRCLR-ALQEGLEQAHFGSPLLPAPG-----ALPGWLEALRVALPVELATAEALVAPCCPPQYNVVQLWAHTLHSGLRRSLQNLLAGPELEAADAFALLHWALHVYLGQEMMGSLELGPEADVSQLEPLLTLENIEQLEATFVANIQASVSQWLQNALDGEVAEWGR-EHGPNTDPSGSYYSPMPAIVLQ-----------------ILEENIRVAS-----LVSESLQQRVHGMALSELGTFLRSFSDALIRFSRDHFRGK----------SMAPHYVPYLLAALNHKSALSSSVSVLQL-------DGAPSGALAPVEAALD---ELQRRIYRLVLEALQAELQPLFADLPSRQWLS-SPELLQSVCERTGRFCRDFW-RVRNPTVQLLLAEAERAVVLQYLSALMQGRLVCRGADERTQAAERLRHDAAQLQQLFLSLGLEENA---HCAPVLLALRELLNLRDPAL--LGLEVAGLRQQFPDVSEDHVSALLGLRGDLSR---EQHLAALSSLQAALPPSPRASRRVLFSLVPAPALAPASCLPSGSCARALLLAE------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AV37-1", "uniprot_id": "EX3L1_DANRE", "id": "A2AV37-1", "name": "Exocyst complex component 3-like protein", "aln": "-----------------------------------------------------------------------------------------------------MSDGDKNGRDNHEEALVPVEVWQELERAECLARGAALKWASGVFCRPEHLEKLGQYKKRESQRTASIQSRLKSV-VQSYLEGVDWGLGQLREARAELRGVSHDLYKANLESR----------------------------KNSEEVTTLETLREISVSHCQLLAAVSNLPRLYKVRS----MVLETERLVESRRLLEAHARLMELERWQDEVLLQLQGPRGSSGTELNSEDEELVRNYFSGVGRLVDALAKELWAVVGSGLSLAHQNPTPFVSAVRIVEREEALDQFFLEERRSTSGHNIP------MPAGRPRNWRDRFFK-VMEEAVSARFRSVSYLHTRGP----GLASHLSALQHCIMGDLSTVRHCLEQCVPAHYHLTRAYLHFCHQFLQTHLG-LVSGWELEGGEIFAVLNWVLHIYNSSEMMGEPALLAELEIENLGPLISQEGLEQLQNKYVQKVRKSVSEWMQKALEVELTDWQR-DQEPDIDHEGYYHTSLPTIITQ-----------------MLEENARVAL-----MISEALRDQTIQMGLYEMEKLLSRFRDAVIEFGKEHRKDP----------TVNKFYLHYLLACINNCIILKTSTESLQQQIC-SFVSNRYSRIPLGPLAALD---RAVRKACRLVMDHLLFELQPHLQELLSSTWLD-QGDVTLNMCGVLERHCELYN-RVRQPCRQRLKEECQWLTVVEYVRAVMQKRLVCRSSDEQKQLAQRMTQDAQQLRDHLQSMEIDGTIGEVNPTALIAALADIINLKDPGM--LLLEISGLLSKYPDISEEHVSVLLDIRGDVPK---EVRKSVLDFLDQSAPPLP-PGYRPIFTEILVPSSSIPFCLPTAKCT-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61333-1", "uniprot_id": "TNAP2_MOUSE", "id": "Q61333-1", "name": "Tumor necrosis factor alpha-induced protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------MLKMVTFFQGFPGQQSVPGTLNFAVSPQKPRSTSEAESETSMSEA-SSEDLMPSPEAPDG----EEESAKKKE---KKSKGLA----------------------------NMFSVFTKGKKKKKDQPRLSDLEVQPKPRPELDGPLP----TVEELKEALEHGRLEVAWQVLALERQLEAAAAAGGMSNEE-------------LVWRQSKVEALYVLLCDQVLGVLRRPLEAAPERLSQALAVVSQEELEDR-RASGGPLAAALEATR-------------PRRWLQRWRG-VVAEVAAERLDAQPATAPEGRSE--AESRFLHMG-RTMKEDLEVVVERLKPLFPDEFNVVRTYAESYHYHFASHLCALAQ-FELCERDTYLLLLWVQNLYPN-DILNSPKLAQELQGVGLGSLLPPKQIRLLEAMFLSNEVTSVKQLMARALELESQRWTQ-DVAPQ-SLDGHCHSELAIDILQ-----------------IISQGQTKAE-----NITSDVGMQIKQLLLVELAALLRSYQRAFDEFLEKS--------------KLLRNYRVNIMANINNCLFFWTSVEQKWQIS---------HDSLNRLLEPLK---DLKAHGFDTLLQSLFLDLKPLFKKFTQTRWAN-PVETLEEIITTVSSSLPEFS-ELQDCFREELMETVHLHLVKEYIIRLCKRRLVLKTAEQQQQLARHILANADAIQGFCTENGSTATW----LHRALPMIAEIIRLQDSSA--IKIEVATYATWYPDFSKGHLNAILAIKGNLPS---SEVRSIRNILDINTGVQE--PPRPLFSLIKVT---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZYQ3-1", "uniprot_id": "D3ZYQ3_RAT", "id": "D3ZYQ3-1", "name": "Tumor necrosis factor alpha-induced protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------MLKMVTFFQGLPGQQSVPGTLDLPGSPQKPRSTSEAESETSMSEA-SSEDLMPSQEAPEG----EEESAKKKE---KKSKGLA----------------------------NMFSVFTKGKKKKKDQPRLSDPEVQSKSRPEEDGPLP----TVEELKEALELGRLEVAWQVLALERQLEAAAAAGGTSDEE-------------LVWRQSKVEALYVLLRDQVLRVLRRPLEAAPERLSQALAVVSQEELEDR-RASRGPLATALAITR-------------PRRWLQLWRG-VVAEVAAERLDAQPAFVPEGRSE--AENRFLHMG-RTMREDMEVVVERLKPLFPEEFNVVHTYAESYHEHFATHLCTLAQ-FELCERDTYLLLLWVQNFYPN-DILNSPKLAQELQGIRLGSLLPPKQIRLLEAVFLSNEVTNVKQLMTRALELESQRWAQ-DVAPQ-SLDGRRHSELAIDILQAQSRAGWAAMLTHCSLQIISQGQTKAE-----NITSDVGMQIKQLLLVELAALLRSYQRVFDEFLEKS--------------KLLRNYRVNIIANINNCLSFRTSVEQRWQIP---------QDSLNRLVEPLK---DLKAHGFDTLLQSLFSDLKPLFKKFTQTRWAK-PVETLEEIITTVSVSLPEFS-ELQDCFREELMEAVHLHLVKEYIIRLSKRRLVLKTAEQQQQLAKHILANADTIQHFCTENGSTATW----LHAALPTISEIIRLQDPSA--IKIEVATYATWYPDFSKGHLNAILAIKGNLPS---SEVRSIRNILDINTGVQE--LSRPLFSLIKVA---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03169-1", "uniprot_id": "TNAP2_HUMAN", "id": "Q03169-1", "name": "Tumor necrosis factor alpha-induced protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEA-SSEDLVPPLEAGAAPYREEEEAAKKKKEKKKKSKGLA----------------------------NVFCVFTKGKKKK-GQPSSAEPEDAAGSRQGLDGPPP----TVEELKAALERGQLEAARPLLALERELAAAAAAGGVSEEE-------------LVRRQSKVEALYELLRDQVLGVLRRPLEAPPERLRQALAVVAEQEREDRQAAAAGPGTSGLAATR-------------PRRWLQLWRR-GVAEAAEERMGQRPAAGAEVP-----ESVFLHLG-RTMKEDLEAVVERLKPLFPAEFGVVAAYAESYHQHFAAHLAAVAQ-FELCERDTYMLLLWVQNLYPN-DIINSPKLVGELQGMGLGSLLPPRQIRLLEATFLSSEAANVRELMDRALELEARRWAE-DVPPQ-RLDGHCHSELAIDIIQ-----------------ITSQAQAKAE-----SITLDLGSQIKRVLLVELPAFLRSYQRAFNEFLERG--------------KQLTNYRANVIANINNCLSFRMSMEQNWQVP---------QDTLSLLLGPLG---ELKSHGFDTLLQNLHEDLKPLFKRFTHTRWAA-PVETLENIIATVDTRLPEFS-ELQGCFREELMEALHLHLVKEYIIQLSKGRLVLKTAEQQQQLAGYILANADTIQHFCTQHGSPATW----LQPALPTLAEIIRLQDPSA--IKIEVATYATCYPDFSKGHLSAILAIKGNLSN---SEVKRIRSILDVSMGAQE--PSRPLFSLIKVG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5H9-1", "uniprot_id": "A0A8M9Q5H9_DANRE", "id": "A0A8M9Q5H9-1", "name": "", "aln": "MYGQLLSESDTYCLTNQHKNTHRYKVAGTLGCPCSETFRDLPSLCCQTSIHPPSATMPVLKNLPSRLKGGRFSVDLETTRSEFILRKMSLNHNPFEEPGSDEDWPRSNGGSLLDGRVPRDRNPFEDEEDENEANEVRRGGSGKGGSIKGTLERMKGVSPLKTLGKLGKNLRLSSR-SKGRETPSPQGSIGSASPMERKKKGRRSSEGSLLRMAGRCKDRKESLTNGELCSETDADSTSRRLSFLKMVGKGKMKRESLQDHSSQGPEEEPVEEVPEVKPREPLSVLEILQLVTKRDLFLADTHILELEQECREAESPTAGGTEDFS---SPSSKDSSRRKAKDVELLYEALQKELWDVVRDSLRCPTAGPNLGLVVQVLQQEEQADRDWAQSEGAAPGGPR-------------PREFRKRWKE-AVVELADANLP----QHAEARAG--ELATFLDKLRVRMVEDLGAARRNAVSVYPAEYDSFQVYTQSYHQAVTRRLQALTN-GDLQITDIYSLLDWLYNIYNR-DVLGTVTITTPINLSQLGPLLPTETVDKLELDCLNSVRGKVTNELSQVLEEEEKRWLD-TLNIE-----EYQIPLARTVIQR-----------------LQEDLERSA-----AVNRHLGSRVAQCSLNGLADFLYSFQRKVEMFHEMLVSSFG---------ENEDGYIAKTIALANCCPSFRSFVQRCGQCDP-----STSEDSIRRANSALD---RIVNLSVRVLNDRLFEHIRPFFDKLIKRKWLS-NTEPFEQIEALIKEHFKKFR-RMDNPPYEVLVVEVHRRVMTEYVRAIMRGRIICTSLKMRKRMAGRLRDEGKHLKTLFKELESSASW----LDSAIPHLSEIILLEDTPS--IQMEVGVLVREFPDIRRKHVSAILNIRGMTRQTERQEILNIVKDIENSDSVARVSRDRALFAEVPVTSEVHCLNLGLSRVALTASNLFSSMRRRRTPTRENHDDVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B7A4-1", "uniprot_id": "A0A8M2B7A4_DANRE", "id": "A0A8M2B7A4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------MALRKVREVWTRSESVLSTYRYKEKDLEKGEEIQGDEHGAEENPEAQYEKQNHKFKIPKNI-KMKNLITSKKNSKSEAVFRPEVVDVDFEAIECIADSP----------------------------EDPEEKSQKSKIKIANKIKLPDFMKRQKNSKYPEAPS----VSLDFNGNLEQNRLADAQQLLVKAEERLFGSNNLGRTEDEE-----------------DKLLRDSEIFRERLKFAILDSFNEENQE-TLKSALISILQEEAQDRRWAEVSENQRPIWR-------------PTECRQKIHDPLLKTLVETRLKNADGQENKADKLSTSLKREVCRTGKQVQKDLLIVVRNLKECYPADFDICRTYAQLYHQTFSARLQELTR-SSIEFEDCAYILSWIKIYYPK-DVLKHKELEQHINSSLLGPLLPEEHLKRLEDQYFSCKENEVRNWLSNAFDKEVDKWSD-GFEPE-LIEGCYFGNLAVDVLP-----------------LIEGTVKEVN-----ALLECESKSWSLLCLLDSS--LLSYGTSLKELVKRKQENIP---------KILRDSLVNIYVFKNYVQKVENFFS---------------EDTRTTRMSILM---DLRNICHTYFLSRIHKELKPVYRKLWTQTWFAGNSEVVEELVKAIEKISNDFK-DLKPACREELLAELHVEVMVEYVRRMMKRKLKLKDKEKQEAAAEFMSQDSNEICSVFVKLGSKEDW----LSKILPKLSEILKLQDPGS--LQIEIATLARDYPDISEQHVLALLNLKANISS---SDLRRIKGCLTDNRSPQE--SSTAFFSKVLVKRKII-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32844-1", "uniprot_id": "SEC6_YEAST", "id": "P32844-1", "name": "Exocyst complex component SEC6", "aln": "----------------------------------------------------------------------------------------------------MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIY----------------------------NFVALMEHIERLLVAELAEDALETGCPHLLEIHFLLTSAR-DFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSKNTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVG--DQKFDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVE-SEPETIIILDILAFDK------TFQDTLKQDFGFTKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQ-----------------MFTQQVEVAAGTNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNHKYDIDPESITPEDECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYM--GSQAQQIADTLDEYLLDIKPQMNSVLFVNFIDNVIGETIIKFLTALS---FEHSFKNKNNKFLEAMKRDFEIFYQLFVKVLDGNESKDTLITQNFTVMEFFMDLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSS--ERKKIVQQATEMLHEYRRNMEANGVDREPTLMRRFVLEFEKQ-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * : . . : : : :: . * : : . : : :: : . : .:: . * . .. : . . : : . : . * : . .:. : * : : . .:: : : : : : : : .: : : . : :: : . . ", "identical_positions": 5, "similar_positions": 68, "identity": "0.5%" }, { "cls_id": "homologset.agr.SGD:S000001331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62847-1", "uniprot_id": "RS24_HUMAN", "id": "P62847-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62849-1", "uniprot_id": "RS24_MOUSE", "id": "P62849-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62850-1", "uniprot_id": "RS24_RAT", "id": "P62850-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W229-1", "uniprot_id": "Q9W229_DROME", "id": "Q9W229-1", "name": "40S ribosomal protein S24", "aln": "MSGTTATIRTRKFMTNRLLARKQMVCDVLHPGLSSVNKTEIREKLAAMYKVTPDVVFAFGFRTNFGGGRSTGFALIYDTLDFAKKFEPKYRLARHGLFEQ-KKQTRKQRKERRNRMKKVRGTAK--AKIGTGKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX32-1", "uniprot_id": "RS24B_YEAST", "id": "P0CX32-1", "name": "Small ribosomal subunit protein eS24B", "aln": "MS-DAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :.******.::* ** ***:* *****. :.* * *:***** :**. *.: .*****:****::.**.::*::: *** **.:**.*:** *: :* :*:***:::** **: **.* *: : :: ", "identical_positions": 66, "similar_positions": 43, "identity": "48.18%" }, { "cls_id": "homologset.agr.SGD:S000001332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35796-1", "uniprot_id": "C1QBP_RAT", "id": "O35796-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRALG-AAATGLRASIPAPPLRHLLQPAPRPCLRPFGLLSVRAGSARRSGLLQP--PVPCACGCGALHTEGDKAFVEFLTDEIKEEKKIQKHKSLPKMSGDWELEVNGTEAKLLRKVAGEKITVTFNINNSIPPTFD-----GEEEPSQGQKAEEQEPELTSTPNFVVEVTKTD-GKKTLVLDCHYPEDEIGHEDEAESDIFSIKEVSFQTTGDSEWRDTNYT-LNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35658-1", "uniprot_id": "C1QBP_MOUSE", "id": "O35658-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRSLG-AAS-GLRTAIPAQPLRHLLQPAPRPCLRPFGLLSVRAGSARRSGLLQP--PVPCACGCGALHTEGDKAFVEFLTDEIKEEKKIQKHKSLPKMSGDWELEVNGTEAKLLRKVAGEKITVTFNINNSIPPTFD-----GEEEPSQGQKAEEQEPERTSTPNFVVEVTKTD-GKKTLVLDCHYPEDEIGHEDEAESDIFSIKEVSFQATGDSEWRDTNYT-LNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07021-1", "uniprot_id": "C1QBP_HUMAN", "id": "Q07021-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRVLG-SSVAGLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACGCGCGSLHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRKVAGEKITVTFNINNSIPPTFD-----GEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDDGKKALVLDCHYPEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTNYT-LNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40513-1", "uniprot_id": "MAM33_YEAST", "id": "P40513-1", "name": "Mitochondrial acidic protein MAM33", "aln": "--MFLRSVNRAVTRSILTTPKPAVVKSSWRVFTVANSKRCFTPAAIMRNQE-TQRVGDILQS-----------ELKIEKETLPESTSLDSFNDFLNKYKFS-LVETPGKNEAEIVR------RTESGETVHVFFDVAQIANLPYNNAMDENTEQNEDGINEDDFDALSDNFANVNVVISKESASEPAVSFELLMNLQEGSFYVDSATPYPSVDAALNQSAEAEITRELVYHGPPFSNLDEELQESLEAYLESRGVNEELASFISAYSEFKENNEYISWLEKMKKFFH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.* * : : :.: . * : . .: * * .:: : : * .:*:. *: : :. . *.::: : *.. * : .* * *: *. :**.: * *:: : .:: . *: .:* : :: :. . .*. * : * . .: :: :: :* . :: : *: . *:: . :: * ..** * : * :* .***:: :*. : * *::***::**.:*.*.: ", "identical_positions": 48, "similar_positions": 97, "identity": "16.61%" }, { "cls_id": "homologset.agr.SGD:S000001334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWE7-1", "uniprot_id": "HORM1_RAT", "id": "D3ZWE7-1", "name": "HORMA domain-containing protein 1", "aln": "MATMQL----RRTASMSALVFPNKISTEQQSLMFVKRLLAVSVSCITYLRGIFPERAYGTR-----------------YLDDLCVKILKEDKNCPGSSQLVKWMLGCYDALQKKYLRMIILAVYTNPEDPQTISECYQFKFKYTKNGPIMDFI--SKNQNNKSSTTSA-------DTKKASILLIRKIYVLMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFDG----DPTYLNVGEVPTPFHTFRLKVTTEKERMENIDSAILTPKDSKIPFQKILMDKDDVEDEN----HNNFDIKTKMNEQNENSGTSEIKEPNLDCKEEEIMQFKKNQS---------------------------------------------SSISQCQVEQLISKTSELDVSESKTRSGKIFQCKMVNGN-QQGQISKENRKRSLRQSGKTVLHILESSS-------------QESVLKRRRVSEPNEHT-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5T7-1", "uniprot_id": "HORM1_MOUSE", "id": "Q9D5T7-1", "name": "HORMA domain-containing protein 1", "aln": "MATMQL----QRTASLSALVFPNKISTEHQSLMFVKRLLAVSVSCITYLRGIFPERAYGTR-----------------YLDDLCVKILKEDKNCPGSSQLVKWMLGCYDALQKKYLRMIILAVYTNPGDPQTISECYQFKFKYTKNGPIMDFI--SKNQNNKSSTTSA-------DTKKASILLIRKIYVLMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFDG----DPTYLNVGEVPTPFHTFRLKVTTEKERMENIDSTILKPKESKTQFEKILMDKDDVEDEN----HNNFDIKTKMNEQNENSGASEIKEPNLDCKEEETMQFKKSQS---------------------------------------------PSISHCQVEQLVSKTSELDVSESKTRSGKIFQSKMVNGNNQQGQTSKENRKRSLRQFRKTVLHVLESS--------------QESVLKKRRVSEPKEHT-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X24-1", "uniprot_id": "HORM1_HUMAN", "id": "Q86X24-1", "name": "HORMA domain-containing protein 1", "aln": "MATAQL----QRTP-MSALVFPNKISTEHQSLVLVKRLLAVSVSCITYLRGIFPECAYGTR-----------------YLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECYQFKFKYTNNGPLMDFI--SKNQSNESSMLST-------DTKKASILLIRKIYILMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFEG----EPMYLNVGEVSTPFHIFKVKVTTERERMENIDSTILSPKQIKTPFQKILRDKD-VEDEQEHYTSDDLDIETKMEEQEKNPASSELEEPSLVCEEDEIMRSKESPD---------------------------------------------LSISHSQVEQLVNKTSELDMSESKTRSGKVFQNKMANGN-QPVKSSKENRKRSQHESGRIVLHHFDSSS-------------QESVPKRRKFSEPKEHI-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF66-1", "uniprot_id": "HORM1_DANRE", "id": "A2BF66-1", "name": "HORMA domain-containing protein 1", "aln": "-MTCEQ----KSRPVQSCQMLPDVVSNEQQSLVLVKKLLAIAISSITYLRGLFSEKAYGRK-----------------YVGELKVYILRED-SCPGAQQIVHWLQGCFDALQRRYLRMVLLSIYCDPDNPQKVTECYQFKIKYTEKGPQMDFE--SKNGQSLTKMACD-------NTQKSSMLLVRKLYMLMQNLGPLPDDVCLNMKLLYYDEVTPQEYQPPGFKED-DNGTLMFER----EPVNLTMGEVVTPFHSIKMNVTTEKKRIEPFEDDVEVCVSTKWSLK---ISEDGMMSET------SVQQECMTKENVITDAGIEYSET----QETQEQPHRHTKE---------------------------------------------DFSTNPKMDNLVKKTADLKVDARKTRSGRIFEP----------QISQLEFPLSQDP--------------------------QPSVPKRRKVSVPK----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5SQP1-1", "uniprot_id": "HORM2_MOUSE", "id": "Q5SQP1-1", "name": "HORMA domain-containing protein 2", "aln": "MATAQLSHNTRTLKASKNTIFPSQVTNEHESLVVVKKLFATCISCITYLRGLFPESSYRDR-----------------RLDDLSLKILREDKKCPGSLHIIKWIQGCFDALEKRYLHMAVLTLYTNPKEPEKVTEIYQFRFKYTKKGTTMDFD--SSSTSFESGTDSE-------DIKKACSLLIRQLYILMQNLGPLPNDVILTMKLHYYNSVTPHDYQPPGFKEAVNSHFLLFEG----EPVSLRMGSVSSGFHSMKVKVTTEATRMLDGENSVS--------------QDD---------------------------GTTEIAHQGLDCDEEEEA-----------------------------------------------------CGSQVQRMNFVHIEPSFESSRKKKK-----------------------------------------------------------VSEPVTVFIPNRK--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JU34-1", "uniprot_id": "A0A0G2JU34_RAT", "id": "A0A0G2JU34-1", "name": "", "aln": "MATAQLSHNPRTLKASKKTIFPSQITNERESLVMVKKLFATSISCITYLRGLFPESSYRDR-----------------YLDDLSLKILREDKKCPGSLHIIKWIQGCFDALEKRYLHMAVLTLYTNPKEPEKVTEIYQFKFKYTKKGTSMDFD--SSSTSFESGAHSK-------DVKKACSLLIRQLYVLMQNLGPLPNDVILTMKLHYYNSVTPHDYQPPGFKEGVNSHFLLFEG----EPVSLQMGSVSSDFHSMKLKVTTEATRMLDGENSVG--------------QDDSTTGIA----------PQGIDCVSQDNGTTEIAHQGLDWDEEEEA-----------------------------------------------------SSSQVQRMNFVHIEPSFESTRKKRK-----------------------------------------------------------VSEPVTIFIPNRK--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N7B1-1", "uniprot_id": "HORM2_HUMAN", "id": "Q8N7B1-1", "name": "HORMA domain-containing protein 2", "aln": "MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGER-----------------HLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMYQFKFKYTKEGATMDFDSHSSSTSFESGTNNE-------DIKKASVLLIRKLYILMQDLEPLPNNVVLTMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDK----EPINVQVGFVSTGFHSMKVKVMTEATKVIDLENNLF--------------REN---------------------------STTEIAHQGLDCDEEEE------------------------------------------------------CNDHIQRMNFVCSQQSSECSRKKRK-----------------------------------------------------------VSEPVKVFIPNRK--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20050-1", "uniprot_id": "HOP1_YEAST", "id": "P20050-1", "name": "Meiosis-specific protein HOP1", "aln": "---------MSNKQLVKPKTETKTEITTEQSQKLLQTMLTMSFGCLAFLRGLFPDDIFVDQRFVPEKVEKNYNKQNTSQNNSIKIKTLIRGKSAQADLLLDWLEKGVFKSIRLKCLKALSLGIFL--EDPTDLLENYIFSFDYDEENNVNINVNLSGNKKGSKNADPENETISLLDSRRMVQQLMRRFIIITQSLEPLPQKKFLTMRLMFNDNVD-EDYQPELFKDATFDKRATLKVPTNLDNDAIDVGTLNTKHHKVALSVLSAATSSMEKAGNTNFIRVDPFDLILQQQEENKLEESVPTKPQNFVTSQTTNVLGNLLNSSQASIQPTQFVSNNPVTGICSCECGLEVPKAATVLKTCKSCRKTLHGICYGNFLHSSIEKCFTCIFGPSLDTKWSKFQDLMMIRKVFRFLVRKKKGFPASITELIDSFINVEDQNNEVKERVAFALFVFFLDETLCLDNGGKPSQTIRYVTSSVLVDVKGIVIPNTRKQLNVNHEYKWHFTTSSPKAESFYQEVLPNSRKQVESWLQDITNLRKVYSEALSPSSTLQELDLNSSLPTQDPIISGQKRRRYDLDEYLEEDKSSVVNDTIKAKDFDESVPAKIRKISVSKKTLKSNW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .:* .:: ::: ....:::***:*.: : : ..: : * .. .. . : * :.::. : *: * :: . : * * * :.* ::. * . . . : :: *:*:: :: *.* ***:. *.*:* : : * :*** **: :. : : :* : : .* . :.* : . .: . . .: : ::: * : : . . *: ", "identical_positions": 35, "similar_positions": 98, "identity": "5.67%" }, { "cls_id": "homologset.agr.SGD:S000001335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IYF3-1", "uniprot_id": "TEX11_HUMAN", "id": "Q8IYF3-1", "name": "Testis-expressed protein 11", "aln": "MISAHCN------LRLLCSSDSSASASQVAGTTEVVENLVTNDNSPNIPEAIDRLFSDIANINRESMAEITDIQIEEMAVNLWNWALTIGGGWLVNEEQK----IRLHYVACKLLSMCEASFASEQSIQRLIMMNMRIGKEWLDAGNFLIADECFQAAVASLEQLYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCK-----DMLMRLPQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQS----YDIGKMDKKSTGPEMLAKVLRLLATNYLD-WDDTKYYDKALNAVNLANKEHLSSPGLFLKMKILLKG-------ETSNEELLEAVMEILHLD---MPLDFCLNIAKLLMDHERESVGFHFLTIIHERFKS---SENIGKVLILHTDMLLQRKEELLAKEKIEEIFLAHQTGRQLTAESMNWLHNILWRQAASSFEVQNYTDALQWYYYSLRFYSTDEMDLDFTKLQRNMACCYLNLQQLDKAKEAVAEAERHDPRNVFTQFYIFKIAVIEGNSERALQAIITLENILTDEESEDNDLVAERGSPTMLLSLAAQFALENGQQIVAEKALEYLAQHSEDQEQVLTAVKCLLRFLLPK-----IAEMPESEDKKKEMDRLLTCLNRAFVKLSQPFGEEALSLESRANEAQWFRKTAWNLAVQCDKDP--VMMREFFILSYKMSQFCPSDQVILIARKTCLLMAVAVDLEQGRKASTAFEQTMFLS--RALEEIQTCNDIHNFLKQTGTFSNDS--------CEKLLLLYEFEVRAKLNDPLLESFLESVWELPHLETKTFETIAIIAMEKPAHYPLIALKALKKALLLYKKEEPIDISQYSKCMHNLVNLSVPDGASNVELCPLEEVWGYFEDALSHISRTKDYPEMEILWLMVKSWNTGVLMFSRSKYASAEKWCGLALRFLNHLTSFKESYETQMNMLYSQLVEALSNNKGPVFHEHGYWSKSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40511-1", "uniprot_id": "SPO22_YEAST", "id": "P40511-1", "name": "Sporulation-specific protein 22", "aln": "MSDHNVNSTFRKTLVELCETATWITSQVYAAKNLEKNDLITVDNKISALYPIAEKYDRSFRTTTVILDEELILKLENAASSLWNSLTIAMKAEKASDKYFNEVFCKCKIFATKLLSIHEALFRTNTNLLRNFKCYISSFKSASEYR-FDDLITNTQQHSEKYLQIINENVESFSNEEKTEFKKLTFEFYLVNFQLYLSENDLDTANIYTAKVNITDNSKYMDADLLIELCRMIYNSTVMLKEINNPETQLVDVNIISFLKDVEKYLELPVENLKSHTDYSNLKYSVLIFMANCLVEGHPQASELEQCDHYLSLLQNEYPNKVDPFILAINLTKRRNIVNPAETIEEILMRMIMSVDVISNFQAVIASINDLSKMNTKFSIVCLDYLLINKLNSKNDSKFLGKAICSRFLITTQSKTMNDSEIAESLENFSTQMERIVSEPLTKHAISCIITLLWNTGKKLEKMEKYVVSIRFYKLALKDIISQNYS-DRGKIQRALQVVYNKIEDYSNTVRVYQDMDEVDRQSPLCQLLMLQSFLADDKTEEALTCLQKIKSSEDEKSTDALILAVAECKRKTDLSVQGLLMIFDKLQSKSNSQTISSTSSSQTLSILRYTLQMIVKVSEEEPLETFINYLPTVQKLLQKAVEFLKTVKLLNQLPPDVEKEAIYQQSVAVNEIEWFASFSYNVAVKCLVDQSCESISEFPQYCIQFIDLIPVQDFTFPKMYHFTYWRFKATILQLIIAKEKAKQDQHQKDWDIYEKSEELVNSINVMKKSSEFKDGSSLEDRNTLHECFLEALTIHLESALMMPDQTRILDILKKTELYQDSRVDALLIDISSNMEDLPKGVLIEILETVLKRNMGPEVKERELCSWLRILLENAIN-LNHEVELRILDRVLKILNINQSSLQDTDGVLQTELETIATYCWNIGVNYIIKDNKSNGIVWCKHSMGFANMVN---EGLQEQLYSLWESLASSANIDINSIAK---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : * * **.: : ::. *... ::*:* **. . .* . :. . . : * :::*: * .*** . ..:: : : .* ****: ** * :: .: * : : *. : * * . *: : :: * * . ::*:*.* ... * :*. : .:: *.: : : . *:*:.* :* . : ::. : . : ** . . : ::..:: .:: .** ::*. :: ::. ::. : :.* ::*: .. . *: * * ** :* *:. :*.: :. : :::*: ... .:.: ::. ::.: .* .: * . ::: *: ...*: . : . : : ... ** .::. : .:**. . . ::::*. ::::* :*: ::: . * *:** : * :::: .:: .. : :. * :. : *: ::: : :.::*.** .: .::. ::.:: *.. . . . **: . : : : * ::. :. *: . : ::: :::. : * :* :. :: .:*. :: .: * . . .** :** . ::*:**:* * : ** . :: :: * ::. : . . : * *. :* . . *: : : *.:*::. *.:.* * :* :.:.: * * :*: : : : . .::: * .: . * .* : :::* : :. : .. :: *:: :: :*** *:.* :: * :. *.. : *: : . .** ** : :.: :.. ** :: * * :. *. : *: *:..*..: . : ..: : ", "identical_positions": 138, "similar_positions": 376, "identity": "13.94%" }, { "cls_id": "homologset.agr.SGD:S000001336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08651-1", "uniprot_id": "SERA_RAT", "id": "O08651-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKILISDSLDPCCRKILQDGGLQVVEKQN-LSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61753-1", "uniprot_id": "SERA_MOUSE", "id": "Q61753-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQN-LSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEAMGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHNPGVPGEQGSGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLVFRAQPSDPGMLPTMIGLLAEAGVQLLSYQTSMVSDGEPWHVMGLSSLLPSLETWKQHVLEAFQFCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43175-1", "uniprot_id": "SERA_HUMAN", "id": "O43175-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQN-LSKEELIAELQDCEGLIVRSATKVTADVINAAEK-LQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKI8-1", "uniprot_id": "Q9VKI8_DROME", "id": "Q9VKI8-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "-----------------------------------------------------MPLNIRKVLVCDAVDKSCVELLEQHGIKVTYKLK-LPVEELCQEVKNFDAAIVRSDTKITAEVLAAGSGSLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTCILIGSLARPVVPAGQSMKEGRWDRKLYAGTELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPITTEAEAKAAGIEKMTLEEIWPLADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLDGLESGKVAGAAFDVYPEEPPKSAV----------TKALISHPKVVATPHLGASTSEAQVRVAVEVAEQFIALN----------------------------------------------------GTSPKYTS------------------------YAGVINKEA----------------------------LAHYQ----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40510-1", "uniprot_id": "SER33_YEAST", "id": "P40510-1", "name": "D-3-phosphoglycerate dehydrogenase 2", "aln": "MSYSAADNLQDSFQRAMNFSGSPGAVSTSPTQSFMNTLPRRVSITKQPKALKPFSTGDMNILLLENVNATAIKIFKDQGYQVEFHKSSLPEDELIEKIKDVHAIGIRSKTRLTEKILQHARN-LVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTAR--QVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYIN--------------------------------------------------EGNSVGSVN------------------------FPEVSLKSLDYDQEN-----------------TVRVLYIHRNVPGVLKTVNDILSDHN--------------IEKQFSDSHGEIAYLMADISSVNQSEIKDIYEKLNQTSAKVSIRLLY-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*: : :: . ::::: * :* : . *. :** :::: .. :** *::* .:: . * :* *.:::*: *: :.: *:*:* .** *..**. : .*** : .:: * *:: *: ****.::* *:** ::: :: *:: : ** : . : : .*:*: .*::*:*.* * * ::. :* *.*. *:* :** ::* ::: .:::.: ****:**:..**.: *:. ::: **:*.**.*** . *:* : *.* .. . : *. : ", "identical_positions": 78, "similar_positions": 123, "identity": "13.0%" }, { "cls_id": "homologset.agr.SGD:S000001337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88761-1", "uniprot_id": "PSMD1_RAT", "id": "O88761-1", "name": "26S proteasome non-ATPase regulatory subunit 1", "aln": "-MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGE--KKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPG------MLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDTQAVSDILEKLVK---EDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTN-TGTVP-------GPEKDSDSMETEEKTAGAVAGKTPDASPEPKDQTLK----MIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVR--NSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASN-------DIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNTQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGVCCAGTGNKEAINLLEPMTN-DPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSR-TGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCIIGLN-KDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVD---------------------------------EAEKKEEKEK-------------------KKEPEPNFQLLDNPARVMPAQLKVLSMTETCRYQPFKPLS-IGGIIILKDTSEDIE-ELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TXS7-1", "uniprot_id": "PSMD1_MOUSE", "id": "Q3TXS7-1", "name": "26S proteasome non-ATPase regulatory subunit 1", "aln": "-MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGE--KKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPG------MLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVK---EDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTN-TGTVP-------GSEKDSDPMETEEKTASAVAGKTPDASPEPKDQTLK----MIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVR--NSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASN-------DIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTN-DPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSR-TGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVD---------------------------------EAEKKEEKEK-------------------KKEPEPNFQLLDNPARVMPAQLKVLSMTETCRYQPFKPLS-IGGIIILKDTSEDVE-ELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99460-1", "uniprot_id": "PSMD1_HUMAN", "id": "Q99460-1", "name": "26S proteasome non-ATPase regulatory subunit 1", "aln": "-MITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGE--KKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPG------MLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVK---EDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTN-TGTVP-------GSEKDSDSMETEEKTSSAFVGKTPEASPEPKDQTLK----MIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVR--NSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASN-------DIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTN-DPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSR-TGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVD---------------------------------EAEKKEEKEK-------------------KKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLS-IGGIIILKDTSEDIE-ELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QK93-1", "uniprot_id": "F1QK93_DANRE", "id": "F1QK93-1", "name": "26S proteasome non-ATPase regulatory subunit 1", "aln": "-MITSAAGIISLLDEDEPQLKEFALHKLNSVVNDFWAEISESVGKIEVLYEDETFRSREFAALVASKVFYHLGAFDESLSYALGAGDLFNVNDDSEYVETIIAKCIDHYTKQRVENAELPEEEE-KKDIDPRLEGIVNKMFQRCLGDHKYKQAIGIALETRRLDIFEKTILESNDIGG------LLAYSLKICMSLMQNKKFRNEVLRVLVKLYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVK---EDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIPAVPGSTN-TGTVP-------TPDKDSDSMETEDKAGSSPAGKTADAKDEPKDQNSK----MIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVR--NSVCHTATVIANSFMHTGTTSDQFLRENLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLSQLKNASN-------DIVRHGGALGLGLAALGTARQDVYDLLKSNLYQDDAVTGEAAGLALGLVMLGSKSAQAIEDMVGYAQETQHEKILRGLAVGIAMVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESIGFIMFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTN-DPVNYVRQGALIASALIMIQQTEVTCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGVLDAGGRNVTISLQSR-TGHTHMPSVVGLLVFTQFWFWFPLSHFLSLAFTPTAIIGLN-KDLKMPKVQYRSNCKPSTFAYPPPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKKEKEEEKMEVETQAEA-----------------------EKEKKDEEKEKEKEK-------------------KKEPEPNFQMMENPARALPAQLKVLTMPDSCRYQPFKPLH-TGGIIILKDTSEEEE-ELVEPVSAHGPKIEEEEQEPEAPEPFEYIDE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3P6-1", "uniprot_id": "PSMD1_DROME", "id": "Q9V3P6-1", "name": "26S proteasome non-ATPase regulatory subunit 1", "aln": "MSLTSAAGIISLLDEPMPDLKVFALKKLDNIVDEFWPEISESIEKIEMLHEDRSFPENKLAGMVASKVFYHLGSFEDALTYALGAGDLFDVNARNEYTETIIAKCIDFYIAQRVEFIENPKEA---SVVDERLEGIVNRMIQRCLDDNQFRQALGIALETRRMDTFKDAIMKSDDVRG------MLAYAYNVTMSLIQNRGFRNEVLRCLVSLYRDLGVPDYVNMCQCLIFLEDPFAVAEMLDNLTRSSVETNNLMAYQIAFDLYESATQEFLGNVLQHLKNTAPIPTALPSTFKPQGTTSEDGAKSEGDKSKSDEDITEETPADDKVERTIDSLNEVEKLHQKNIEKLISILSGEVSIDLQLQFLIRSNHADLQVLRGTKEAVR--VSICHTATVIANAFMHSGTTSDQFLRDNLDWLARATNWAKLTATASLGVIHRGHEKDSLALMQSYLPKEAGPSSGYSEGGALYALGLIHANHGANIIDYLLQQLKDAQN-------ENVRHGGCLGLGLAGMGTHRQDLYEQLKFNLYQDDAVTGEAAGIAMGMVMLGSKNAQAIEDMVSYAQETQHEKILRGLAVGISLTMFSRLEEADPLVTSLSSDKDPVLRRSGMYTIAMAYNGTGSNKAIRKLLHVAVSDVNDDVRRAAVTAIGFILFRSPEQCPSVVSLLAESYNPHVRYGAAMALGIACAGTGLREAIALLEPMVKFDPVNFVRQGALIASAMILIQHTDQSCPKSTFFRQLYAEVISNKHEDVMAKYGAILAQGIIDAGGRNATLSLQSR-TGHTNLQAVVGMLAFTQYWYWFPLAHTLSLAFTPTCVIGLN-SDLKMPKMEYKSAAKPSLYAYPAPLEEKKSEEREKVATAVLSIAARQKRREN-ADKKEDEKMDVDEDSKEGAAVKKDEEAKADEKMVTDEKPKKKDEKEKKKEEDKEKEAAGTSSEKDKDKEKDKKEKKEPEPTSEILQNPARVLRQQLKVLSVIDGQSYEPLKDVT-IGGIIVFQHTGKAEDQELVEPVAAFGP-MNDEEKEPEPPEPFEYIED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32565-1", "uniprot_id": "RPN2_YEAST", "id": "P32565-1", "name": "26S proteasome regulatory subunit RPN2", "aln": "MSLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLFKKLKE---ENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLN------------------------------------------------------------ILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLPGSR-ASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTK-DPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENADTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEK----------------------------KKEHEEKEKERETNKKGIKETKENDEE-----FYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 314, "similar_positions": 351, "identity": "30.11%" }, { "cls_id": "homologset.agr.SGD:S000001338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9R8-1", "uniprot_id": "A0A8I6A9R8_RAT", "id": "A0A8I6A9R8-1", "name": "Coatomer subunit epsilon", "aln": "MAPPAPGAVSGSSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENRRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNP--DAALRTLHQG---DGLECTAMTIQILLKLDRLDLARKELKRMQEQDEDAT------LTQLATAWVNLAMGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDS----------GHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRTHPFIKEYQAKENDFDRLALQYAPSA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89079-1", "uniprot_id": "COPE_MOUSE", "id": "O89079-1", "name": "Coatomer subunit epsilon", "aln": "MAPPVPGAVSGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENQRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNP--DAALRTLHQG---DGLECMAMTIQILLKLDRLDLARKELKKMQDQDEDAT------LTQLATAWVNLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDS----------GHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRLAMQYAPSA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14579-1", "uniprot_id": "COPE_HUMAN", "id": "O14579-1", "name": "Coatomer subunit epsilon", "aln": "MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNP--DAALRALHQG---DSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT------LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDS----------GYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0Y5-1", "uniprot_id": "Q9Y0Y5_DROME", "id": "Q9Y0Y5-1", "name": "Coatomer subunit epsilon", "aln": "MSRQQNEEDTNS-----VLFDARNEYYIGNFMGSINFVLPEQGTAGP---ELLSYMYLSYLAIDSGRIVASDIKEGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETN-IWHLATAIVYCHDGQF--ENALKILHGS---TNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDAT------LTQLAQAWVALAQGTEQMQDAFHIYQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKH----------NDYDTLINLMVHAHLTGKPTEAITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQYDVEGGEKLLAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40509-1", "uniprot_id": "COPE_YEAST", "id": "P40509-1", "name": "Coatomer subunit epsilon", "aln": "----------------MDYFNIKQNYYTGNFVQCLQEIEKFSKVTDN---TLLFYKAKTLLALGQYQSQDPTSKLG-----KVLDLYVQFLDTKN-----IEELENLLKDKQNSPYELYLLATAQAILGDLDKSLETCVEGIDNDEAEGTTELLLLAIEVALLNNNVSTASTIFDNYTNAIEDTVSGDNEMILNLAESYIKFATNKETATSNFYYYEELSQTF-PTWKTQLGLLNLHLQQRNIAEAQGIVELLLSDYYSVEQKENAVLYKPTFLANQITLALMQGLDTEDLTN---QLVKLDHEHAFIKHHQEIDAKFDELVRKYDTSN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :: :* *.: .:: . : : : ** . * . :.: : : : . : :* : . : . : * :* * : : .:. :. . * :::: * :.:. * . . : :*:. : :** ::: :* . * . :: ::*:.:. ** * * . *:.::. * . * * :. : * .* .. ** . *:.. : . .**.* :* . ", "identical_positions": 36, "similar_positions": 91, "identity": "10.71%" }, { "cls_id": "homologset.agr.SGD:S000001340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAW1-1", "uniprot_id": "A0A8I6AAW1_RAT", "id": "A0A8I6AAW1-1", "name": "threonine--tRNA ligase", "aln": "MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQAEGPRLTREVAQLQAENRDLHQRLCDLRLRLAEQGG----------PGARRAAAHEPPTQNQEKDTKRKRLKDSEPNREVK-QPNFIKERLQLFETLKTDHQLLPATQEKK-NTNNVISVRVAGGKTVQGEEWKTTPYQVAAGISKELAENTVIAKVNGVLWDLDRPLEGDS----TVELLMFDNEEAQAVYWHSSAHVLGEAMELYYGGHLCYGPPIENGFYYDMFIGD----------RVVSSTELSALENICKTIIKEKQPFERLEVSKDSLLEMFKYNKFKCRILKEKVDTP-TTTVYRCGPLIDLCKGPHVRHTGKIKAIKIFKNSSTYWEGNPEMETLQRVYGISFPDSKMMRDWEKFQEEARSRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLMDFIREEYHKRNFTEVLSPNMYNSKLWETSGHWQHYSNNMFTFDIE-----------------KDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLHRNELSGTLTGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLSTRPEHFLGETEIWDEAERQLQNSLTGFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMIIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKLNNSVNVRTRDNK----IHGEISITSVIEKLKNLKKSRTLNAEEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLY2-1", "uniprot_id": "SYTC2_MOUSE", "id": "Q8BLY2-1", "name": "Threonine--tRNA ligase 2, cytoplasmic", "aln": "MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQAEGPRLTREVAQLQAENRDLHQRLCGLRLRLAEQRR----------TEAGRAAAHEPPTQNQEKDTKKKRLKQSEPGREVK-QPNFIKERLQLFETLKTDHQLLPATQEKK-NTNNVISVRVAGGKTVQGERWKTTPYQVAAGISKELAEHTVIAKVNGVLWDLDRPLEGDS----TVELLMFDNEEAQAVYWHSSAHILGEAMELYYGGHLCYGPPIENGFYYDMFIED----------RVVSSTELSALENICKTIIKEKQPFERLEVSKDTLLEMFKYNKFKCRILKEKVDTP-TTTVYRCGPLIDLCKGPHVRHTGKIKAIKIFKNSSTYWEGNPEMETLQRIYGISFPDSKMMKDWEKFQEEAKSRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNALMDFIREEYHKRNFTEVLSPNMYNSKLWETSGHWQHYSNNMFTFDVE-----------------KDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLHRNELSGTLSGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLSTRPEHFLGEIEIWDEAERQLQNSLVEFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMVIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKINNAVNVRTRDNK----IHGEISIASVIEKLKNLKKSRTLNAEEDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RTX5-1", "uniprot_id": "SYTC2_HUMAN", "id": "A2RTX5-1", "name": "Threonine--tRNA ligase 2, cytoplasmic", "aln": "MAAEALAAEAVASRLERQEEDIRWLWSEVERLRDEQLNAPYSCQAEGPCLTREVAQLRAENCDLRHRLCSLRLCLAEERSRQATLESAELEAAQEAGAQPPPSQSQDKDMKKKKMKESEADSEVKHQPIFIKERLKLFEILKKDHQLLLAIYGKKGDTSNIITVRVADGQTVQGEVWKTTPYQVAAEISQELAESTVIAKVNGELWDLDRPLEGDS----SLELLTFDNEEAQAVYWHSSAHILGEAMELYYGGHLCYGPPIENGFYYDMFIED----------RAVSSTELSALENICKAIIKEKQPFERLEVSKEILLEMFKYNKFKCRILNEKVNTA-TTTVYRCGPLIDLCKGPHVRHTGKIKTIKIFKNSSTYWEGNPEMETLQRIYGISFPDNKMMRDWEKFQEEAKNRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLTDFIREEYHKRDFTEVLSPNMYNSKLWEASGHWQHYSENMFTFEIE-----------------KDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSGTLSGLTRVRRFQQDDAHIFCTVEQIEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGEIEMWNEAEKQLQNSLMDFGEPWKMNPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKKRPVIIHRAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQVSSEFFEEGFMADVDLDHSCTLNKKIRNAQLAQYNFILVVGEKEKIDNAVNVRTRDNK----IHGEILVTSAIDKLKNLRKTRTLNAEEAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0R2-1", "uniprot_id": "SYTC_MOUSE", "id": "Q9D0R2-1", "name": "Threonine--tRNA ligase 1, cytoplasmic", "aln": "-----------------------------MSQEKASSPSGKMDG-EKPVDASEEKR------------------------------------------------KEGGKKKSKDGGGDGGRAELNPWPEYINTRLDMYNKLKAEHDSILAEKAAK--DSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVVAKVNKVVWDLDRPLETDC----TLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEE----------GGVSSNDFSSLETLCKKIIKEKQTFERLEVKKETLLEMFKYNKFKCRILNEKVNTP-TTTVYRCGPLIDLCRGPHVRHTGKIKTLKIHKNSSTYWEGKADMETLQRIYGISFPDPKLLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNTLMEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVE-----------------KEQFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEIWNQAEKQLENSLNEFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSH--DGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADTDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKASGTVNIRTRDNK----VHGERTVEETVRRLQQLKQTRSKQAEEEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHY5-1", "uniprot_id": "SYTC_RAT", "id": "Q5XHY5-1", "name": "Threonine--tRNA ligase 1, cytoplasmic", "aln": "-----------------------------MSEEKASSPSGKMDG-EKP---------------------------------------------------------------------------LNPWPEYINTRLDMYHKLKAEHDSILAEKAAK--DSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVVAKVNKVVWDLDRPLETDC----TLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEE----------GGVSSNDFSSLETLCKKIIKEKQTFERLEVKKETLLEMFKYNKFKCRILNEKVNTP-TTTVYRCGPLIDLCRGPHVRHTGKIKTLKIHKNSSTYWEGKADMETLQRIYGISFPDPKLLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNTLMEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVE-----------------KEQFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEIWNQAEKQLENSLNEFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSH--DGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQEFHDAKFMVDIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKASGTVNIRTRDNK----VHGERTVGETVERLQQLKQLRSKQAEEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26639-1", "uniprot_id": "SYTC_HUMAN", "id": "P26639-1", "name": "Threonine--tRNA ligase 1, cytoplasmic", "aln": "-----------------------------MFEEKASSPSGKMGGEEKPIGAGEEKQ------------------------------------------------KEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEK--DSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDC----TLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEE----------GGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTP-TTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVE-----------------KELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSH--DGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNK----VHGERTISETIERLQQLKEFRSKQAEEEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKB0-1", "uniprot_id": "Q9VKB0_DROME", "id": "Q9VKB0-1", "name": "threonine--tRNA ligase", "aln": "-------MLKLAPQGGRYYSQISRICQWILPKIQTQSKPPKQQQQQQPQLKEQQQHSYATL-----------------------------------------AAKMKKEKKEKPSGGGDTRKELSPLPKYIEERNVFWEKCKAEYE---AELAAK--KREPIKVTLPDGKQVDATSWETTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNC----TLQLLKFDDPEAQAVFWHSSAHIMGEAMERIYGGHLCYGPPIENGFYYDMHLEG----------EGISTNDYGAMEGLVKQIVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTTD-RTTVYKCGSLIDLCRGPHVRHTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKEWEKLQEEAAKRDHRKIGREQELFFFHELSPGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVISPNIYNAKLWMTSGHWQHYAENMFSFEAE-----------------KEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAPEQIKSEMKGCLEFLKYVYTIFGFSFQLVLSTRPDNYLGELEQWNDAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRAHQCATIQLDFQLPIRFNLSYIAD--DGE-KKRPVIIHRAILGSVERMIAILTENFAGKWPFWLSPRQVMVVPVGPAYDQYAQSVRDQLHDAGFMSEADCDAGDTMNKKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNK----VHGEVSVAELITKLQKIRDEFIAN-EDSF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04801-1", "uniprot_id": "SYTC_YEAST", "id": "P04801-1", "name": "Threonine--tRNA ligase, cytoplasmic", "aln": "---------------------------------MSASEAGVTEQVKKLSVKDSSND-------------------------------------------------AVKPNKKENKKSKQQSLYLDPEPTFIEERIEMFDRLQKEYNDKVASMPRV-----PLKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNGQLWDLDRPFEGEANEEIKLELLDFESDEGKKVFWHSSAHVLGESCECHLGAHICLGPPTDDGFFYEMAVRDSMKDISESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHYSKYKTYLVQTKVPDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFPDKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVE-----------------KETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFLQYIYGVFGFEFKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGPKIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTG-NTLQKKVRNGQMLKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLRNLKDEKRGDNVLA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M9PJQ9-1", "uniprot_id": "A0A8M9PJQ9_DANRE", "id": "A0A8M9PJQ9-1", "name": "threonine--tRNA ligase", "aln": "------------------------------MVIPVFSRWPVRLAAVRAAGWN-----------------------------------------------------------------------CRHYGKLVHERLQVFQSLRDRLLKASGSPSGR-----DLAIRLADGRTVKGSAGVTSPLQIAR---SERVTGAVVSRVNGELWALSRPLLEDC----ELQLLGFDSLEGKEVVWRTGACVLASVLERVFSAGVCREGVSDTGLYCDYQLQD-------------SSISLLEVEQACKQVAAGKIPITTLELTLQDLKELFQDNAVRLQLAEEQMMGD-TVGVFRCGDSVGVCSGLLLPHTGFLKAFKMLQVSPVTLSGSSEASGILRMIGVSFPSEREREQWEKEQEEARRRDHRRIGKAQELFFFHDVSPGSCFFMPKGAHIYNTLTDFIKSEYRRRGFSEVVTPTLFSTALWERSGHWQHYSENMFSVSSE-----------------THTFALKPMNCPAHCVMFEQRLRSWREMPIRWADFGALHRNEASGTLGGLTRVRRFCQDDAHIFCTPEQLELEITACLDFVRSVYRVFGFSFHCLLSTRPASSMGDSALWDCAEQQLESSLKLFQERWELNPGDGAFYGPKIDILIRDALGRQHQCATIQLDFQLPIRFNLQYVGA---DGQMKRPIMIHRAVLGSLERMIAILAENFGGKWPFWLSPAQVMVVPVGGSSEAYAQQVVSRLREAGFMADIDDDHGNTLNKKIRSAQLAQYNYIFVVGEKESECGTVSVRTRAGQ----QIGQKTLEDVMKTLTQLTETRSNEELI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UQ84-1", "uniprot_id": "SYTM_MOUSE", "id": "Q3UQ84-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "-----------------------------MGLCLRWRRLGFPLPEFRRCELHTVRE-----------------------------------------------------------------ASAPTPPHWLAERFGLFEELWTAHVKKLASMTQK--KARAIKISLPEGQKVDAVAWNTTPYQLAHQISVTLADTAVAAEVNGELYDLDRPLETDC----HLRFLTFDSPEGKAVFWHSSAHVLGAAAEQQLGAVLCRGPSTESGFYHDFFLGK---------ERTVRSAELPILERICQELIAAAQPFRRLEASRDQLRQLFKDNHFKLHLIEEKVTGP-TATVYGCGMSVDLCRGPHLRHTGQIGALKLLTNSSALWRSLGAPETLQRVSGISFPKVELLRNWEARREAAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYARRGFSEVKTPTLFSTKLWEQSGHWEHYRADMFSLKPPGTDGVDNSQSGHPARCPKDTLALKPMNCPAHCLMFAHRPRSWRELPVRLADFGALHRAEASGSLGGLTRLWRFQQDDAHIFCAPHQLEAEIQGCLDFLRCVYSVLGFSFHLALSTRPPGFLGEPRLWDQAEQVLQQALEKFGEPWDLNPGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGP---AGTPECPVLIHRAVLGSVERLLGVLAESCGGKWPLWLSPLQVVVIPVRTEQEEYARQVQQCLQAAGLVSDLDADSGLTLSRRVRRAQLAHYNFQFVVGQREQSQRTVNVRTRDNR----QLGERDLAESVQRLLELQNARVPNAEEVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FW7-1", "uniprot_id": "SYTM_RAT", "id": "Q68FW7-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "-----------------------------MGLCLRWRRLGFPLPGFRRCELHTVRE-----------------------------------------------------------------APIPTPPHWLAERFGLFEELWTAQVKRLASMTQK--KARTIKISLPEGQKVDAVAWNTTPYQLAQQISSTLADTAVAAEVNGELYDLDRPLETDC----HLRFLTFDSPEGKAVFWRSSAHVLGAAAEQHLGAVLCRGPSTESGFYLDFFLGK---------ERTVRSTELPTLERICQEIITAAQPFRRLEASRGQLRQLFKDNHFKLHVIEEKVTGT-TATVYGCGMSVDLCQGPHLRHTGQIGALKLLTNSSALWRSSEAPETLQRVSGISFPKAELLRNWEARREEAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRIYNALVAFIRAEYARRGFSEVKTPTLFSTKLWEQSGHWEHYRAHMFSLKPPGTDGVDSSQSGHPARCPKDTLALKPMNCPAHCLMFAHRPRSWRELPVRLADFGVLHRAEASGSLGGLTRLWRFQQDDAHIFCAPSQLEAEIRGCLDFLRSVYSVLGFSFHLALSTRPPGFLGEPHLWDQAEKVLQQALEEFGEPWNLNPGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGP---AGAPECPVLIHRAVLGSVERLLGVLAESCGGRWPLWLSPFQVVVIPVRTEQEDYARQVQQCLQAAGLVSDLDADCGLTLSRRVRRAQLAHYNFQFVVGQREQSQMSVNVRTRDNR----QLGERGLAESVQRLLELQDARVPNAEELF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW92-1", "uniprot_id": "SYTM_HUMAN", "id": "Q9BW92-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "-----------------------------MALYQRWRCL--RLQGLQACRLHT--------------------------------------------------------------------AVVSTPPRWLAERLGLFEELWAAQVKRLASMAQK--EPRTIKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDS----DLRFLTFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGK---------ERTIRGSELPVLERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGP-TATVYGCGTLVDLCQGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTKLWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRPRSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLRSVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQ---AGALERPVLIHRAVLGSVERLLGVLAESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRAQLAHYNFQFVVGQKEQSKRTVNIRTRDNR----RLGEWDLPEAVQRLVELQNTRVPNAEEIF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .:. . : : : * .. *:* ::* . :.** : *.* : :. :.:* *:. *.: * *::.: ::. * .. :* : *:: : : . :* : : : * . * :*: . : : : :: . *: ** :.:* * : *** : :*: *. . . : *: *:*** . * ****:**: ***::*:::******: *:*: :**:* ::: ** :*.: ** :*.::.: ** **** :* .**:.. .. :.*******.**::* * **:**:* * ****.:** * ** * ****: * ******** *:: *: :.*:: :* :**.*: ***** :*. *: ** * .:* : *. *.***********: : **: * ***.********* **:* : . : *:::***:***:**: .:*:* .*:**:**** **:::** : ** .. . : : * *:.:::* .*: ::*: ::**::* :*.:*.* . : . : * :: . : ", "identical_positions": 198, "similar_positions": 188, "identity": "23.57%" }, { "cls_id": "homologset.agr.SGD:S000001341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC15-1", "uniprot_id": "ZCHC7_RAT", "id": "B1WC15-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGFETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYSQNIHNANEEEG-------------YEE----KNCESSETVSIQPDQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAQEKTQSPATPRSNK--VANKCKRSNKKPEPEESPSTIREVMIIEVSSDEEEESTI-SENENVESWMLLGCEED-------------------------------------------------DKDNDILLNLVGCKDAGAEGENDVN----WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRPCCLCSERGHLQYGCP-ARYCLDCSLPMSSTHRCFERSSWRKR--CDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCY------NCAQ-------KGHYGHECTERRMF-------------------------NQAFPTSPFIYCYD---------DKYDIQQRDR-RIKRKLKDIKKNGDFP-----------------RQFKRPHGEETD-RYHHDRRK---------SRFSGKRSRWPRE-----------SKETQKE-KTRGREGEKHRRDRQ---PRDEDEDFPRGLKPNSS-SSSNS------QKPSKS--------------------------------------------------------LHQASHYHRLREEKLRRE--SMRSKPKKR-KFVEDGSHDDLFLIKQRKKKPKSSGF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AX39-1", "uniprot_id": "ZCHC7_MOUSE", "id": "B1AX39-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGYETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYAQSIHNANKEEG-------------YEE----KNCENSETVSSQPNQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAEEKTQSPATSHSNK--VAQKCKRNNKKPKPEERPGVIREVMIIEVSSNEEEESTT-SENENVESWMLLGSEED-------------------------------------------------GKDNDILLNLVGCETAGA--EDDVN----WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRACCLCSERGHLQYGCP-ARYCLDCSLPMSSNHRCFERLSWRKR--CDRCDMIGHHADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCY------NCAQ-------KGHYGHECTERRMF-------------------------NQTFPTSPFIYCYD---------GKYDIQQRDR-RIKRKVKDLKKNGDFP-----------------RQFKRPHVEETDKRRHHDMRK---------SRSPRKYRRWPRE-----------NKETQKE-KTRSREGKTHRRGHQ---PRGEDEDFPRGSKPNAS-GCANN------QKPSKS--------------------------------------------------------LHHASHYHRLREERLLRE--SKRSKPKKR-KSTEDGSHDDLFLIKQKKKKPKPSGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3Z6-1", "uniprot_id": "ZCHC7_HUMAN", "id": "Q8N3Z6-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFGGYETIEAYEDDLYRD--ESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEE-------------HEE----KNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTI-SEGDNVESWMLLGCEVD-------------------------------------------------DKDDDILLNLVGCENSVTEGEDGIN----WSISDKDIEAQIANN---------------------------------------------------RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCP-APLCEYCPVPKMLDHSCLFRHSWDKQ--CDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCY------HCAQ-------KGHYGHECPEREVY-------------------------DPS-PVSPFICYYD---------DKYEIQEREK-RLKQKIKVLKKNGVIP-----------------EPSKLPYIKAANENPHHDIRK---------GRASWKSNRWPQE-----------NKETQKEMKNKNRNWEKHRKADR---HREVDEDFPRGPKTYSSPGSFKT------QKPSKP--------------------------------------------------------FHRSSHYHTSREDKSPKE--GKRGKQKKKERCWEDDDNDNLFLIKQRKKKS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5M8-1", "uniprot_id": "A0A8M3B5M8_DANRE", "id": "A0A8M3B5M8-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSPLSNHVCVAPYFCAQAVEITLSLLGFLPRALLEMFSGLQERYDHEDELYRDEEDSSGLSDSDSELEFRLYSQLHYNAEFQENHEESS-------------KVQPLVPQTQLQPETMPPAPPVDVIVIDSGPDSFTVSDST-----EDDESVCANKVQSLKHCKRKSQPSRFRSPSPPQVQAGRSSPDDVVVLDSDLEQSSSESEPPFVEDLDSDTDSD-SDSDGLENWMILGKGRQ-------------------------------------------------DGDQSIQLNLAQSSFVNTEYVNYRGQEQKWTVSEKDKQAQIYNKGHGP-----------------------------------------------RHVPNRSTYRYYTEKSITCRNCNKTGHLSKNCPTLKKVPCCSLCGLRGHLLRTCP-NRHCSNCSLPGHTSDDCLERAFWYKR--CHRCGMTGHFIDACPQIWRQYHLTTTAGPIRKSADPKACQKRAYCY------NCSR-------KGHFGHQCSQRRMY-------------------------NWSYPSLPVITYYD---------TVNDIKCRDF-RLKKKAREMQDAGLISPDGGVVTFTPQPPRKKQKVSHSPHPYSNNTNNHHTPKKRIAHTPKHNPQTNQQNTHWRVKQNSKKPGPHGKNTPQSKEFKSQNKEAKNKKRKKKKAAVIDEDADFPRGSKKSPHKAGFHSSTQKANVKPVKL--------------------------------------------------------FGVEKNHMKKKDKSKKKERIQRKRQQKAAKDSAAYPTDENLFQIKQRKVKRSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40507-1", "uniprot_id": "AIR1_YEAST", "id": "P40507-1", "name": "Protein AIR1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLLSEVESIDTLPYVKDTTPTGSDSSSFNKLLAPSIEDV-------------------------------------------------DANPEELRTLRGQGRYFG-------------ITDYDSNGAIMEA------------------------------------------------------------------EPKCNNCSQRGHLKRNCP---HVICTYCGFMDDHYSQHCPKAIICTNCNANGHYKSQCPHK-WKKVF--CTLCNSKRHSRERCPSIWRSYLLKT-----KDANQGDFDFQTVFCY------NCGN-------AGHFGDDCAERRSS-------------------------RVPNTDGSAFCGDN---------LATKFKQHYFNQLKDYKREASQRQHFD-----------------NEHEFNLLDYEYNDDAYDLPG---------SRTYRDKMKWKGK------------VQSTRNKNSSNNRYESSNNRKKKSPFSAQNYKVTKNKRVQTHPLDFPRS-----SQNNRT--------------------------------------------------------NDYSSQFSYNRDDFPKGP------KNKRGRSSSNKSQRNGRY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VVA9-1", "uniprot_id": "Q9VVA9_DROME", "id": "Q9VVA9-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "MSDLEEMDSERLNELESILYASIHYSDGFEEHTAMDQPAKESTSDQDARSMPPPPQQKHPIPGQRFVSGTRVINNSMQKPRYWIDGAAAVGEGQVVQAEEQQATTNKTMPAVEESSSSQSMDVDMPQDKSLLLSPEKGTSNQPKTASQPPKHQQIPQAKQQQNIHAKQLQNQQAKPQEQKNSQQKQQQSLKQQNQQSKQHQNQQKKSAPVVQKPKPQPNASTKVNHEAYEAERFDQRLLVAIPPNCPPKKQNKPQQNKQQQQQNKQQQKKQQQSLQHNKQQQQSGPGPFGKANRKLEQIQRLADKKQKSKQAQLNKKQRKQQSPPVEFVNLAETSESSDDDDVVHVPLPPAPIIELDTSDGEQTCTSSQLFHEENAMDATDVKMGLSCITEPEGTSVVASSTTPPMHSPSCSVMSSDDFIVQKDTTRLLTECENANDEDLLVLTETAIREAIGEEPKDKEVVENASEEQEHDHAADTSSEYEFVPPSRLEEIKKNYRVDDQQFRALDVYESESDLTESGIYSKAKSKTTPTIIRNVDSSSGSSSVEEVVEPSVQKTKRLRKRSCSTNNHSQSDPNNDDGLDDSDSDDGVHATGVPGIARGMAVERCKRKIRRISTRHSSDDNSKKAATRIQKPKVAAVHHASSESASEDELPSARDIAERLLNQQQGQGKVQVQKGDGDDDAISIGSDEDSHAEAEFRDAMTDRLAAVFERLDAKAKKMEEDEEQVNASGYISDEEDSRDKSADTTVRSDEDIDASNDLEETNPDKNDRDVTNEEQHVHVEHNLQELRDESLPKSGDLIGWNEEMRSFYNDSWNGENFSVHKVQRMMTGHRHEWRINTADRCPVARPRSHAKCSNCFEMGHVRSKCPRPRKPLVCFICGTMGHAEPRCP-NAICFGCGSKQEIYVQQCNKCSFHSRLVCQLCKMRGHGVDHCPDKWRRYHSTTRSNTELDSRVQYRSVQCSYCAGRHSFENCRQRIGDFRSTNYTSQIVSHQKIYKNRGGPIGNLGDLKSFFAIETPFHFKWNNPSMPKNCYYSRFLVNANLAKVQSVKRKSTTAVSQIPEKIYTHEYVPNAQVKAARGEVSTGTAKKPLTKQMPVVESIAENRTAEEPIG-KLNREDEKSKDILPLPEVPPEVKQTQDEKLVEGQPNQSQPDEELPMKDDDQEEPSSSVQREEITTNFDNPPTEPGLSRTPLAPHELDSDSNYSFSEHFELPSSTTSDGQPNTQLPLVRTMGTLPDVIPLSKDDFELSSNVQGISMCVNSSSTSLRTDETPDPDSSEELPDVPSEGKIIMAREESEYLFSAEGRTFLAAAAKQCHVSVRMDFKDYGYVLVIYGLKKHQEELQVKLLRRSQEVKRKSIEFQSQKPPKRIDVLIRFLRDGINSLNTNLGNAKSHYVRIKELEGMNTKNGFKMAEKKRRQLNMILVGQAGLLNGKTHLDQLLVLLRRLIDDFSPDEHATPQLRNEIEEHWRMIFSSYPHPNYDSLLNSYGRLDQKNRLPSLHIDPVLLGLQQKKTQSQPQSPSKGPPSPTPLPPVRQDMAPPPPPKMSKKKQRQALDQQTQNQQRQQQQQQQRLQQQHQNQQQRLQQQQKQQQQSLQQQHQQQRVQQQRMQQQQQHQQQDNNQYQQNLRRPQIDQMPYNNLQQRSRSDLQLRHTLNPECDRLLSEMDHNQPGSINKDANKPSMFWSRESLKYLDDLFKMTSNTETVERLKRVLQRSQRGLLSHNDYRAVIRLHSLMCN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..... :. : . . . . ::: : . : . * ** : **: :** : .* ** * * : * * * : *.. ** * .* .. :* :* . .: .. ..:. . . . ..: : :. . . . . . : . ... . ... . . . : . : : ", "identical_positions": 22, "similar_positions": 74, "identity": "1.27%" }, { "cls_id": "homologset.agr.SGD:S000001345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDG5-1", "uniprot_id": "PPCS_MOUSE", "id": "Q8VDG5-1", "name": "Phosphopantothenate--cysteine ligase", "aln": "-------------------------------------MAEMDLVAELPRPAGAARWAEVMARFAARLGEQGR-RVVLITSGGTKVPLEARAVRFLDNFSSGRRGAASAEVFLAAGYGVLFLYRARSAFPYAHRFPPQAWLSALRPSGPAQSGKLSLEAEENALPGFAAALQSYQEAAAAGTFLAVEFTTLADYLHLLQAAALALSPLGSSAMFYLAAAVSDFYIPVSEMPEHKIHSSG-------------------GPLQITMKMVPKMLSPLVKDWAPKAFVVSFKLETDPDIIISRARNALEVYQHQVVVANILESIKSFVIIVTKDSETELLLSEEEVAKGLVIEEKIVDDLRSRHTAFICDKN---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6X7-1", "uniprot_id": "D4A6X7_RAT", "id": "D4A6X7-1", "name": "Phosphopantothenate--cysteine ligase", "aln": "-------------------------------------MAEMDLVAELPRPEGAARWAEVMARFAARLGEQGR-RVVLVTSGGTKVPLEARAVRFLDNFSSGRRGAASAEVFLAAGYGVLFLYRARSAFPYAHRFPPQAWLSALRPSGPAQSGKLSLEAEENALPGFAAALQGYQEAAAAGTFLAVEFTTLADYLHLLQAAALALNPLGSSAMFYLAAAVSDFYIPVSEMPEHKIHSSG-------------------GPLQITMKMVPKMLSPLVKDWAPKAFIVSFKLETDPDIIISRARNALEVYQHQVVVANILESIKSFVIIVTKDSETKLLLSEDEVARGMVIEEKIVDDLRSRHTAFICDRN---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HAB8-1", "uniprot_id": "PPCS_HUMAN", "id": "Q9HAB8-1", "name": "Phosphopantothenate--cysteine ligase", "aln": "-------------------------------------MAEMDPVAEFPQPPGAARWAEVMARFAARLGAQGR-RVVLVTSGGTKVPLEARPVRFLDNFSSGRRGATSAEAFLAAGYGVLFLYRARSAFPYAHRFPPQTWLSALRPSGPALSGLLSLEAEENALPGFAEALRSYQEAAAAGTFLAVEFTTLADYLHLLQAAAQALNPLGPSAMFYLAAAVSDFYVPVSEMPEHKIQSSG-------------------GPLQITMKMVPKLLSPLVKDWAPKAFIISFKLETDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEEKIVDNLQSRHTAFIGDRN---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E2QD26-1", "uniprot_id": "E2QD26_DROME", "id": "E2QD26-1", "name": "", "aln": "------------------------------------MTHWEDFYNTHLPPADFEDNRSLLKEFCERHNKLQN-RIVLVTSGGTTVPLEHNTVRFVDNFSAGTRGSASAEYFLDHDYAVIFMHRHKSLEPFTRHFTGQQFFDMLDIADNSQSSTIAIKPDS--VDVFAPVLAKYKIARETQMILYVNFTSVVDYMWLLRAACECLAAFEERAVLYLAAAVSDFYIPEDMMPTHKMQSGD-------------------GAPTISLQLVPKMLAPLASLWVPHAFVVSFKLETDESLLIVKARDSLNKYKHKLVIANVLQTRKHRVVFVTPTDSYELHLTREQTLQGLEIEEPIVADVVQKHGEFISNAQQRQXPLSMRRRPQTQHQQHHHQQLATGDEDEDGGDLDRDPYCVTSSHYCRVLNPGTPGFARKY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40506-1", "uniprot_id": "PPCS_YEAST", "id": "P40506-1", "name": "Phosphopantothenate--cysteine ligase CAB2", "aln": "MPPLPVLNRPQIHTSVTEISHAIDRTIKEELFPVAYTTEEEQYFKTNPKPAYIDELIKDAKEFIDLQYSLKRNKIVLITSGGTTVPLENNTVRFIDNFSAGTRGASSAEQFLANGYSVIFLHREFSLTPYNRSFSHSINTLFLDYIDSE--GKIKPEFAEN-VLKNKKLYDKYMEKEEK--LLLLPFTTVNQYLWSLKSIAKLLN--NSGCLFYLAAAVSDFFVPYSRLPQHKIQSGDNGKMGANNDTEGTTRTTPDGKLIVNLDPVPKFLRRLVESWATQAMIVSFKLETDESMLLYKCTQALDRYNHQLVIGNLLQTRNKQVIFVSPENRKGDWVRLDEKHH--SIEEMIIPEVIARHDKWVAHSKTKLATK---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .* . ::**:*****.**** ..***:****:* **::*** ** .*.*:*::* * *: : *. . * . . : : . : * :* : **:: :*: *:: . * .::*********::* . :* **::*.. * :.:. ***:* *.. *..:*:::******* ::: :. .:*: *:*::*:.*:*:: : *.:*: . : :: : *** *: :: :* :: . : ", "identical_positions": 85, "similar_positions": 95, "identity": "19.72%" }, { "cls_id": "homologset.agr.SGD:S000001350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWH0-1", "uniprot_id": "S38A7_MOUSE", "id": "Q8BWH0-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAQVS--INSDYSEWASSTDAGERARLLQSPCVDVVPK------SEGEASPGDPDSGTTSTLG-AVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCG-KLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMSK----EPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVVGTWYVTAIIIIKY-IWPDKEMRPGDILTRP------------------------------------------------------------ASWMAVFN-----AMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYP---SEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLR----YKGMPVEEDVGRERRRRVL-------------------------------------------------------------------------QTLVWFLLTLLLALFIPDIGKVISVIGG-LAACFIFIFPGLCLIQAKL--------------------SEMEEVKPAS---------WWALVSYGVLLVTLGAFIFGQTTANAIFVDLLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6JWR2-1", "uniprot_id": "S38A7_RAT", "id": "Q6JWR2-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAQVS--INSDYSEWGSSTDAGERARLLQSPCVDVVPK------REGEASPGDPDSGTTSTLG-AVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCG-KLTGVLCEIAIAVYTFGTCIAFLIIIGDQQDKIIAVMAK----EPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASSLSVVGTWYVTAIVIIKY-IWPDKEMRPGDILTRP------------------------------------------------------------ASWMAVFN-----AMPTICFGFQCHVSSVPVFNSMRQPQVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYP---SEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLR----YKGTPVEEDVGRERRRRVL-------------------------------------------------------------------------QTLVWFLLTLLLALFIPDIGKVISVIGG-LAACFIFIFPGLCLIQAKL--------------------SEMEEVKPAS---------WWALVSYGVLLVTLGAFIFGQTTANAVFVDLLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DEL1-1", "uniprot_id": "S38A7_DANRE", "id": "Q6DEL1-1", "name": "Sodium-coupled neutral amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MSRPDRAINSEAGDWGYSEDAGERAWLLQSPSVDSVQ----------PPSQSDDSRGGTSSLG-AVFIVVNAALGAGLLNFPAAFNMAGGITAGVTLQMCMMAFIITGLVILAYCSQVSNESTYQEVVRAVCG-KALGVICELAIAVYTFGTCIAFLIIIGDQLDKLIGAINN----ESEKEISLHWYTDRKFTITLTSVLIILPLSIPKEIGFQKYASTLSVIGTWYVTIIVIVKY-IWPSKDVSPGIIPVRP------------------------------------------------------------ASWTDVFN-----AMPTICFGFQCHVSSVPVFNSMKKPEIRPWWGVVTISMIICLFVYTGTGVCGFLSFGSSVSQDVLMSYP---SDDVAVAIARAFIIICVVTSYPILHFCGRAVLEGLWLR----FKGEEVETDVAKERRRRIL-------------------------------------------------------------------------QTLVWFCLTLILALFIPDIGRVISLIGG-LAACFIFVFPGLCLIQAKL--------------------SEHD-VRSNS---------WNAMVAYGVIMVTIGAFIFGQTTTNAIYKDIINNPNSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G4J0-1", "uniprot_id": "A0AC58G4J0_DANRE", "id": "A0AC58G4J0-1", "name": "", "aln": "MSVSSLRSVSFGPYTEQMILVFPASMYAEPFAWLTSPQRANTGRTSPFPRTPCLLLGALGALSGDRKSNGDCDSSGPRIRFVSTGIFNKPTCLREHSLLCSGETTQSSSRNQMLRDAAIKCCLRAAALCRIGITWQIDGLHILPEESYLTVAFQLKTGLEALRMEELARESIRSI-----SLLSKPARGSDVPRLGSFG-AIFIMLKSALGAGLLNFPWAFEKAGGVNTAISVEMVSLVFLISGLVILGYASSISRQNTYHDVVRNVCG-RRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLCLSLYETVTGNTEAEMPHHWYTDYRFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLAATYLSVAVIAKYYLKDTHTADLT-PEHSQGL----------------------------------------------------------GSWASMFS-----VVPTICFGFQCHEASIAIYSSMENKKITHWVFISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYP---GNDVVMIIARLLFGISIVTIYPIILLLGRSVILTQILR-FWERR--TIMTPVF-EGRCRLI-------------------------------------------------------------------------LTILWITVTLLIAIFVPDMSEVISVIGG-ISAFFIFIFPGLCLIFVMQ--------------------TEPINHRIRI-----------LLTGWGVVTIVIGAFIFGQSTTIAVMELAHKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5WVQ9-1", "uniprot_id": "A5WVQ9_DANRE", "id": "A5WVQ9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELAKESI--------SFLSKSSLETNEPRLGSLG-AVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGRNTYQGVVTDICG-PAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEINLS-PLYSSGI----------------------------------------------------------SSWDSVFS-----VIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYS---GGDVTMIVARLLFGISIITIYPIIVLLGRSVIQDPLLR-RRLKH--TAVTESY-ESRTRVA-------------------------------------------------------------------------LTTAWVTVTLLIAVFIPDISKVISVVGG-VSAFFIFIFPGLCLIFVVQ--------------------SESVSPTMRY-----------LLVTWGMITLLCGTLIFGQSTSVAIMQLITEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A0Y7-1", "uniprot_id": "D4A0Y7_RAT", "id": "D4A0Y7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTRGSR--------GLPEKPLPATTHPPLSSLG-AVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCG-PAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLLP--------DAPQPWYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLIRQPGPLLSP------------------------------------------------------------SPWTSVFS-----VFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYP---GNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATQGSPVLADPS-GPWVRLP-------------------------------------------------------------------------LTFLWVAVTLAMALFLPDLSEIIGVIGG-LSAFFIFIFPGLCLISAVD--------------------TEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH7-1", "uniprot_id": "S38A8_MOUSE", "id": "Q5HZH7-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQPRGSR--------GPLEKPLPAATHPTLSSLG-AVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCG-PAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLLP--------DAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLIRQPGPLLSP------------------------------------------------------------SPWTSVFS-----VFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYP---GNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATRGPPVLADPS-GPWVRLP-------------------------------------------------------------------------LTFLWVVVTLTMALFLPDLSEIISIIGG-VSSFFIFIFPGLCLICAVD--------------------TEPMGPRVKC-----------CLEAWGILSVLVGTFIFGQSTAVAMVELL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969I6-1", "uniprot_id": "S38A4_HUMAN", "id": "Q969I6-1", "name": "Sodium-coupled neutral amino acid transporter 4", "aln": "-------------------------------------------------------------------------------------------------------------------------MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTG-IILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFG-WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMG------LEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFP------------KRPFSWIRHFL-------------------------------------------------------------------------IAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK--------------------KETFRSPQKVG---------------ALIFLVVGIFFMIGSMALIIIDWIYDPPNSKHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HBR0-1", "uniprot_id": "S38AA_HUMAN", "id": "Q9HBR0-1", "name": "Solute carrier family 38 member 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAAAASNWG-LITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQS-CMFLVKSASLSKRRTYAGLAFHAYG-KAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFG----------FQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQS--FSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSY----------------------------------------------------------VRWEGVFR-----CIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFP----SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCE--QQQKDGTFAAGGYMPPLRFKA-------------------------------------------------------------------------LTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40501-1", "uniprot_id": "AVT7_YEAST", "id": "P40501-1", "name": "Vacuolar amino acid transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEATSSALS-STANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFFTLCMLTYPTLAPIFDLAMIVQCFGVGLSYLVLIGDLFPGLFGGERN--------------------YWIIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDICWWK-------------------------------------------------------IHDFKGLLS-----TFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIVGLSGYLTFGNETLGNLMLNYD---PNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVIIWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGSIESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGSTSISFTLPGLLGYKLIG--------------------LDSLAIGKMIPPK------DRFYKRCSLLLVFYGLSVMFLSLYVTVFNRSDEA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: :* . * :. .: * : . : : . . : :: :: . . .::**. :.: : :. : : :: .. : :.* .. .: . : :: .: ... *:::* . ::: : . : : . : *:: * : : . : : . ::.. *. .: : * *.: . . ", "identical_positions": 13, "similar_positions": 88, "identity": "0.89%" }, { "cls_id": "homologset.agr.SGD:S000001353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M9G7-1", "uniprot_id": "UTP25_RAT", "id": "Q5M9G7-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKPQICQLSESSDS-----SHSESESESEQEHVSG-YHRLLATLKNISEEEEEEEEEEEEEEEDKEE-----VDDSAVGDSEMNGEDGGED------VRVEETAESSETQDHMSLADNSKGK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEESGGSYSQRTSQDPFQHHINKELQEKEIQAAASSPAATQQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQKPLESTWAKTNSQFLSGPGPQKSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LASVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYAHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKSVHLFITGEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTT6-1", "uniprot_id": "UTP25_MOUSE", "id": "Q8BTT6-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRNRGRSQMLSTMTKKQKKHLRDFGEEHPFYDRVSKKEAKPQICQLPESSDS-----SHSESESESEQEHVSG-YHRLLATLKNVSEEEEEEEEEEEEEEEEEEEEEEEEEDDSAVGDAEMNEEAGSEDGSVGEAAVSEAAEEAAETQEHMSLADNSKEK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEDSGGSCSQRPSQDPFQQHVNKELKEKEIQAAASSPPATQQLKWPVLGHLVFSSKFQKTETFKPPKDIDLKLLHLQKPLESTWAKTNSQFLSGP--QKSNSSFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RSQKLGVGEDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSVELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCINAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LSSVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGISRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKNVHLFVTGEK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CQ4-1", "uniprot_id": "UTP25_HUMAN", "id": "Q68CQ4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDS-----SDSESDSESEPQQVSG-YHRLLATLKNVSEEEEEDEEEEEEE-------------DSIVDDAEMNDEDGGSD----VSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGP--QKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRR-------RSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAEN--LASVIDARFNFFVNKILPQYRDAV--MSHTLIYIPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEH4-1", "uniprot_id": "UTP25_DANRE", "id": "Q6PEH4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRR-RGK-QEIDNLTKKQKKHLKEFGEQHPFHDKVVERPEKTQILRLPDSPQR-----PEPDSEDDSDAEQPSA-YQKLLSTMIQGDEDDVESEDEESEEEDNEEE-------AEVEGDSEEEVEDTDEE----DGNDAEEVLEDKVEETSDKLQKKHPEKTNGDVEENEEAEMEGEFTDKKNEAAFCLETNMPAEGEENTAQQEQDEDMFVKHQEIELSEEEVGRISQGSKVKTQVKWAKLGVLQCMCPLERFPAIGQASSAPLPPIH--KTLEANWHLLNLPFGAAT-------DVTELQKEMLGLMGTYRDLYLANLSPLKEAKEVRSAYCLHALNHVLKANSRVLRNNAKL-------KESKNG---DEDFRDQGLTRPKVLILVPFRDGALRVVQTFMTLLEP---KGKK-TDASNKKRFKEEYGEETDEKPPNLQRPDDYHAVFSGNIDDHFRIGMSILRHSMRLYAPFYSSDIIIASPLGLRTVLGAEGEKKRDHDFLSSIELLIVDQADVFLMQNWEHLLHVLEHLNLQPLDSHGVDFSRVRMWNLNNWAAYYRQTLVFSAIQEPQITNILTKHCHNYRGQVCSKTIP--KIGSICQVLVQLPHVFQMFHSDS--FMD-QDARFQFFVDKILPQYRDSV--MSHTFIYVPSYFDFVRLRNYLKKED-VSFANISEYSQRSEVSRARHYFQKGEKQFLLFSERFHFYKRYTIKGIHNLIFYGLPTYPHFYSEVCNMLQAGVRE--GGASVSFTCTALYSRYDVHRLAAITGADRAAQMLQSKKTTHLFITGEEKST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G1-1", "uniprot_id": "Q9W1G1_DROME", "id": "Q9W1G1-1", "name": "Digestive organ expansion factor homolog", "aln": "MKQKHSKNRAKPYKKPTPARRNER--FSKNYSFIQRSKQMEESHRRERMPTAPKQEYEPVAELLPEIQDDVDETEF-YKKLITGVNNIPTSDILRSKAEKEE-----------------------------------------------DHVIPVPRKIKPKKEKRSEQLGVDLEIYNSFS------------------------KRFDFELSTDNINDLIARKDVKTIKRNWSALGNVRFDIPRLTEDFKEPDCSEPKDIASTEDLQKLEVKASICANAKLP----------------LTALQSQLFYIANNYQDIYYPHRTHG-NAEDIRYVYCLHALNHMLKVRSLILRNNEKVSALAKSQKMSPNEISIPESFRDQGLKRMKVVFVVPFRESALRIVNILGDLLFGSQDDQARKTSIANYERFLGDYSGNTIYFPKTNPKPMDYEQTFSGNTDDNFKLGIRFTKKTMSLFSDMNASDMLIASPLGLRMLVT---DKESDFDFLNSIELLIIDQAELFLAQNWENLLHSLDHLHLQPQKLPDTNCQRVRTWCLSGASSFYRQTLFFSSHELPEFRAVFNSKCNNYQGKVRDSNLV--EHGDIRNVLTPIHQVFRLINCSS--VETTFDDRFQYFVKNIMPQFSKPG--FSHCMLYVPSYFDYVRIRNHFKTEM-VSFVQINEYTKKEKISRARDIFFHSGASVLLYSERAHFFRRTRIKGIRNLIMYQPPNFPHFYSEIINLMLKTNQNPRDGFGDEMSVSILYTKYDLLSLSNIVGSENAAKLTSGQKDSYLFSTKT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40498-1", "uniprot_id": "UTP25_YEAST", "id": "P40498-1", "name": "U3 small nucleolar RNA-associated protein 25", "aln": "MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDED--EVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRRE----------------------------------------------ADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKK-----TDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQ------------DNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIIS--------KSGIDQVDKKGKFYDQFRDDS---LPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLG-NTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : . ::. : .. . : . : .. .. . : : :. . .:: : .: . . .* : . . . . : .: : : .:: : .* **.::. *:*: : : .: * *.**.:**: *.. :* ** : .. ***:.* **:::** *: * *:*: : : :* :: :. :* .:. * ** :* * :*: : :::: *:: : **:::.****:: :: .*: : ***.*:**:::** . ** .::: ::*:: * . .: .*:* * :. : :***:.* . ::. * * *: .: ..* : : ::*: :. . . * **::* . *:* .. . ::*:*.* *::*:**::* : : * .* **:.: :. * * :. ..:* :** *.::* ***::.:::* *. ..**.*: .:: : :*:: * * :.* ..** : . * : * ", "identical_positions": 110, "similar_positions": 210, "identity": "13.66%" }, { "cls_id": "homologset.agr.SGD:S000001357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GK59-1", "uniprot_id": "A0A8I6GK59_RAT", "id": "A0A8I6GK59-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFS---RMPKSEG-SGGGAAAGGAAGSGLGGGFGS--SSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSG------IRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFALPFGES-QVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSILPSTLPEPMTATEAAARK-----SQMKARITDTIGPTETSIAPRQRPKAN---------------------------------------STAAISSVLTIQSSATPVKVPAPGEFSNHK-PKGALRPGNGSDILMVQGPTQQPPQQHRVLQQLQQGDWRLQQLHL-HRHP------QQQQQQQQQQQQQQQQQQQQQQ------------------------------------LLQNAYLQQYQHAMHQQQILQQQFLMHSVYQPQPLASQYPTMMQQYQQALLQQQMLAHHQQPAQQVSPEYLTSPQEFSPALAPYGSSLPAQVGTIVDSS--------------------------------------------------------------------YGATSRSVAEKEAVANFT--NQKTISHPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLGESTPS------------------------------------------------DKNVDPPPAPHSRPPEEPFASVPFISHSGSPEKK-TEHSPNQKNITAHPTKNGSSSPICK---AGQKTSENPV---------VRGHAQKGNDESESEFESDPPSPKSSEEEQEDED--AQGEHGDFNDEDTEPENLGHRPLLMDSEDEEEDDKHSSDSECEQAKAKGGESSSLRRNKPGGAP--------------------------------------EPASSP--ALTPSQEFDVFGAVPFFAVPAP-ELQHRGSG--KSVSQQMFP----EQEEYDVFTKAPFSKKVTVQDWPAVRPDTRPLPARPRSVDIFGS-TPFQPFSTAASKSESKEDVFGLVPFEEITGSQQQQQKVKQRSLQKLSSRQRR-------TKQDVSKSNGKR----------------HHGTPTSAKKPLK--------------------------PPYRTPERARRHKRVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPPDESLLDP----FGAKPFHPPDL-WHQTHQGLSDICVDHTAILPGRPRQNSVHGSFHSADALRMDDFGAVPFTELVVQSVSP---QQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z96-1", "uniprot_id": "BMP2K_MOUSE", "id": "Q91Z96-1", "name": "BMP-2-inducible protein kinase", "aln": "MKKFS---RMPKSEG-SGGGAAAGGAAGGGLGGGFAS--SSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSG------IRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-QVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFLPSTLPEPMTATEAAARK-----SQMKARITDTIGPTETSIAPRQRPKAN---------------------------------------STAATSSVLTIQSSATPVKVPAPGEFSNHK-PKGALRPGNGSEVLMVQGPPQQPPQQHRVLQQLQQGDWRLQQLHL-HRHPHHHHQQQQQQQQQQQQQQLQQQQQQQQQ------------------------------------LLQNAYLQQYQHAMHQQHILQQQFLMHSVYQPQPPASQYPAMMQQYQQAFLQQQMLARHQQPAQQVSPEYLTSPQEFSPALVSYASSLPAQVGTIVDSS--------------------------------------------------------------------YGAN-RSVAEKEAVANFT--NQKTISHPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLGASTPS------------------------------------------------DKTVDLPPAPHSRPPEEPFASVPFISHSGSPEKKTTEHSPNQKSITANLTKNGGSSPLCKDQRAGKKTSENPV---------IRGQVQKGHDDSESDFESDPPSPKSSEEEQEDED--AQGEHGDFNDDDTEPENLGHRPLLMDSEDEEEDDKHSSDSECEQAKTKRGDTSSLRRDKPGVAPDTAL---------------------------------LTPARSPADALTPSQEFDVFGAVPFFAAPAPQSLQHRGDG--KNLSQHAFP----EQEDFDVFTKAPFNKKVSVQDWPAVGPDARPLPARPRSVDIFGS-TPFQPFSVSASKSESKEDVFGLVPFEEITGSQQQQ-KVKQRSLQKLSSRQRR-------TKQDVSKSNGKR----------------HHGTPTSAKKTLK--------------------------PPYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPSDESLLDP----FGAKPFHPPDL-WHQPHQGLSDICVDHTTILPGRPRQNSVHGSFHSAETLRMDDFGAVPFTELVVQSVTP---QQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSY1-1", "uniprot_id": "BMP2K_HUMAN", "id": "Q9NSY1-1", "name": "BMP-2-inducible protein kinase", "aln": "MKKFS---RMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGG------IRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-QVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARK-----SQIKARITDTIGPTETSIAPRQRPKANS--------------------------------------ATTATPSVLTIQSSATPVKVLAPGEFGNHR-PKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHH----------------------------HHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGTIMDSS--------------------------------------------------------------------YSAN-RSVADKEAIANFT--NQKNISNPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLEERASS------------------------------------------------DKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTS-------------VQGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLN---------------------------TILLTSAQLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNE---KNLPQHRFPAAGLEQEEFDVFTKAPFSKKVNVQECHAVGPEAHTIPGYPKSVDVFGS-TPFQPFLTSTSKSESNEDLFGLVPFDEITGSQQQK--VKQRSLQKLSSRQRR-------TKQDMSKSNGKR----------------HHGTPTSTKKTLK--------------------------PTYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDP----FGAKPFHSPDLSWHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQSQQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UHJ0-1", "uniprot_id": "AAK1_MOUSE", "id": "Q3UHJ0-1", "name": "AP2-associated protein kinase 1", "aln": "MKKFFDSRREQGSSGLGSGS-SGGGGSSSGLGSGYIG-------RVFGIGRQQVTVDEVLAEGGFALVFLVRTSNG------VKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPAKLPEPVKASEAAVKK-----TQPKARLTDPIPTTETSIAPRQRPKAG---------------------------------------QTQPNPGILPIQP-ALTPRKRA-----------------TVQPLPQAAGPSNQPGLLPSVSQPKAQATPSQPLQSSQPKQPQAPPTPQQTPATQTQGLPTQAQATPQHQ-----------------------------------------QQHLLKQQQQQQQQ-----PQQPTAPPQPAGTFYQQQQQQQQQQAQTQQFQAVHPAAQQPVTAQFPVGSQGGAQQQLMQNFYHQQQQQQQQQQQ--------------------------------------------------------------------LMAQQAALQQKTAVVVPQ-SQAQPATAPQAAAAQEPGQIQAPVRQQPKVQTTPPPTIQGQKVGSLTPPS------------------------------------------------SPKT-QRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVSNASEG----------------------STWNPFDDDNFS-KLTAEELLNKDFAKLGEGKLPEKLGGSAESLIPG---FQPTQGDAFTTPSFSAGTAEKRKGGQAVDSGIPLLSVSDPFIPL----------------------------QVPDAPEKLIEG--LKSPDTS-LLLPDLLPMTDPFGSTSDAVIDK-ADVAVESLIPG----LEPPVAQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTAGLLEEFAPIALSAPTHKAAEDSNLISGFGVAEGSEKVA-EDEFDPIPVLITKNTQ-------GGHSRNSSGSS-----------------ESSLPNLARSLLL--------------------------VDQLIDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C1X8-1", "uniprot_id": "AAK1_RAT", "id": "P0C1X8-1", "name": "AP2-associated protein kinase 1", "aln": "MKKFFDSRREQGSSGLGSGS-SGGGGSSSGLGSGYIG-------RVFGIGRQQVTVDEVLAEGGFALVFLVRTSNG------VKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSQDMHCLI-YMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPTKLPEPVKASEAAVKK-----TQPKARLTDPIPTTETSIAPRQRPKAG---------------------------------------QTQPNPGILPIQP-ALTPRKRA-----------------TVQPLPQATGPSNQPSLLASVSQPKAQATPSQPLQSSQPKQPQAPPTPQQTPAPQTQGLPTQAQATPQHQ-----------------------------------------QQLLLKQQQQQQQQQQQQQPQQPTAPPQPSGTFYQQQQPQQQQAQTQQQFQAVHPAAQQSVTAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQ--------------------------------------------------------------------LMAQQAALQQKTAVVVPQ-PQAQPATAPQAAAAQEP-QIQAPARQQPKVQTTPPPTIQGQKVGSLTPPS------------------------------------------------SPKT-QRAGHRRILSDVTHSAVFGVPASKSTQLLHAAAAEASLSKSKSATTTPSGSPRTSQQNVSNASEG----------------------STWNPFDDDNFS-KLTAEELLNKDFAKLGEGKLPEKLGGSAESLIPG---FQATQGDAFATSSFSAGTAEKRKGGQAVDSGIPLLSVSDPFIPL----------------------------QVPDAPEKLIEG--LKSPDTS-LLLPDLLPMTDPFGSTSDAVIEK-ADAAVESLIPG----LEPPVAQRLPSHTESVTSNRTDSLTGEDSLLDCSLLSNPTADLLDEFAPIALSASTHKAAEDSNLISGFGVAEGSEKVA-EDEFDPIPVLITKNTQ-------GGHSRNSSGSS-----------------ESSLPNLARSLLL--------------------------VDQLIDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M2I8-1", "uniprot_id": "AAK1_HUMAN", "id": "Q2M2I8-1", "name": "AP2-associated protein kinase 1", "aln": "MKKFFDSRREQGGSGLGSGS-SGGGGSTSGLGSGYIG-------RVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNG------MKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-TEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKK-----TQPKARLTDPIPTTETSIAPRQRPKAG---------------------------------------QTQPNPGILPIQP-ALTPRKRA-----------------TVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQ-----------------------------------------QQLFLKQQQQQQQP--------PPAQQQPAGTFYQQQQ------AQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQ---------------------------------------------------------QQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEP-AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPS------------------------------------------------SPKT-QRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEG----------------------STWNPFDDDNFS-KLTAEELLNKDFAKLGEGKHPEKLGGSAESLIPG---FQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFIPL----------------------------QVPDAPEKLIEG--LKSPDTS-LLLPDLLPMTDPFGSTSDAVIEK-ADVAVESLIPG----LEPPVPQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNLISGFDVPEGSDKVA-EDEFDPIPVLITKNPQ-------GGHSRNSSGSS-----------------ESSLPNLARSLLL--------------------------VDQLIDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6K5-1", "uniprot_id": "A0A8M3B6K5_DANRE", "id": "A0A8M3B6K5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFFDSRRELVGSGPGSGGGAGGSGSGSGAGGNFIG-------RNFTVGRHQVTVEETLAEGGFAIVFLVRTNQG------VRCALKRMYVNNEHDLQVCKREIQIMRDLNGHKNIVGFLDSSITAVGGGDVWEVFILMDFCRGGQVVNLMNQRLQTGFSEQEALQIFCDTCEAVARLHQYKTPIIHRDLKVENILLHDRGHYVLCDFGSATMKFQNPQ-SEGVTAVEDEIKKYTTLSYRAPEMVNLYNGKIITTKADIWAMGCLLYKLCFFTLPFGES-QVAICDGNFTIPDNSRYSQDMHRLIRYMLEPDPDKRPDIYQVSFFAFKLARRDCPVQNVKNSPIPAKLPEPIRASEAAAKKS---QTQTKARLTDPIPTTETSITPRQRPKAAQ-------------------------------------SQSQALGGILPIQPAALTPRKRA-----------------NLP-----AG-AAQP-IAVSVN-------FAQPAAALQSQKAQASPAPQQ----KTQPIPVTVTATAGG---------------------------------------------------------------IPAASPTP-------------------QKAVATPPPSSPAPPTAPARSAR------------RKQASVAQQQS--------------------------------------------------------------------VVAPPTATQP--AVAQPP-AQAEPTAAPP--TVQQP----APQSQISPEDAEERPAAPG---LSQTPPS------------------------------------------------SPRTAQKAGHRRIQSDVTHSAMFGVPVSQSTQQLQAATAEASLNKSKSASATPSNSPQSSQQSVYQPAQQQASVSVPQAPASAANLTSPPTQPTWNPFDDDNFS-KLTAEDLLNKDFTKLAD-EPVEPLIVTSDSLIPG---LEAAE-------SAPPSSAERPADILGLEPGAGLLAV----------------------------------------PEKLIEG--LKSPDTS-LMLPDLLSMADPFGSSIEETRDVNTDVCLDSLIPG----LEPPQAQLQPVEAESASLVLTDPLIGDDSLLGG-PLSSSSASCLDDFAVLSGGPSQNIPAAEPCLISGFEPS-SAETAN-EDEFDPIPVLVSKNSQDDLPSVNGYESASCIQSSDVPAEEEEEEEVLHMCSGSKLPLLDSKLLN--------------------------TTSLKLSPSSSPDVFSSAPFPG------CGPDSRDIFTSAPFPQIQPSHPQPDVFLQAP----FYKRSESHVAQISNGDDPVLPHP-PVHSQIRFPYCAEAPMPQQPIAAHRVVSSVGQQAAISSVPVGP-LHSW-TVGVRAVMDPFLAAPFQPRGPLGKP---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BFD5-1", "uniprot_id": "A0A8M2BFD5_DANRE", "id": "A0A8M2BFD5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFFDARREMVSSGPASGAGAGGGAGS----GAFIG-------RVFSIGRYQVTVEETVAEGGFAIVFLVRTHQG------VRCALKRMYVNNEHDLQVCKMEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFSESEVLQIFCDTCEAVARLHQCKPPIIHRDLKVENILLHDRGHYVLCDFGSAINRSQNPQ-TEGVAVVEEEIKKYTTLSYRAPEMVNLYGGMVITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSHDMHCLIRYMLEPDPDMRPDIFQVSYFAFKLSRRDCPVQNVHNSPIPTKLPEPIRASEAVAKK-----SQNKARLTDPVPTTETSIAPRQRPKAG---------------------------------------QAQPITGILPIQP-ALTPRKRP-----------------SAP-----PGPSQPISVNMASQPPVAQQQATPSPPQTTPQHAQLFVQQQNTAFFTAQQQQNHSTQTQMPA-----------------------------------------AS--------------------PSTQSKP-------------------KNRAPPPPMHHPQPDRLTTLSATTQTKPKAMAPAPPAESSHSVDGE----------------------------------------------------------------------ASVSAQPKTKAMAPPPPASHASTTLPPPNSTSAA----STYSGGEPEQRSAAGSRGVHKVGSLTPPS------------------------------------------------SPKAAPKGGHRRILSDVTHSTIFGVPVSKSTQLLQAAAAEASLNKSKSASTTPSGSPCSSQQSVYQPADASG--------------HSAGATGSWNPFGDDNFS-KLTAEELLNKDFAKLDAKTAER---SCPENLISG---LQSVS--------SNKGFLQGGAGMDSLIPGLDPLQTDLKSAALP---------------------------ECLVGRDSLLDGSLLSHPSAGGLLLSSPSSLPVPSVDQFTALSSGPSHQASDQNHP-----LSGFQSSETGDQSSDNQFDPIPVLNSKSSSQEAEGKSDGYGIADDDENPTEEDFP-HSSDEDDAEKGGRSQVSGDETPS-LDCSGSRPLLQDSDDE-------DEQSPASSRNLR---------------MSSASEVASENQSE--------------------------IQAQRSGADPSVDVFSKAPFRIGQNLDDNNSNEGDVFTNAPFLRPP---AQPDIFLQAP----FGRKKEASG--------KVYTNP-VIHPMFLQGSSIDQSILGPVAPLQFQPQELSKYSRHYEEPVNSDPEHN-MASDMSSGDPFVSAPFHLKGRHEKR---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ30-1", "uniprot_id": "Q9VJ30_DROME", "id": "Q9VJ30-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKILSKFERNENSRLENPPNSSSSSSSNEKNSFVG--------KVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSS-ATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTG-NGVCEVLLLMPYCK-HHMLAMMNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQ-QHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFGES-TLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPKGSSSVHGGNPLGLGLPPSPSPRQNITSPQPQPQPVVEQFQANFPAMPPAVPPPPQAVTPAAPAASKLFESSGYPDPFNEPAAAVIPTEFLPAAEEPNKEEVPQDLNVIAGTPTKSMLTPPKPSGGGGHRRNVSDTSAFNKTFANETSQFLAPFNNNLAAMGDGQQTLASAASNPGIYASSTANSAAVSISELMKPGQTAVEKRVEAWNPFEEEQPFSQMTEDHIFEAEFDKIRQRGSQGSITAKSASTTSTLTPTEQIPSAVVAPVTAAPGAVPPPPIAAAVSPYPSQVSEDPFGSAPFSLPPGLREKASSLRKTGAKFIGVSSGGTGGGVATPIGLVAGGANTATSSNSSKWMLSPTLEVSSEEKTSLISKLKTDSECGIPGAVGGAGEGVSGYVKLPVEDRNKYEKLRSKDQPTSDDSDSEASEFFQQDSDEGGGGIFRQMQMVTSNLPETIHKIQQVAYHKVDKTAHLPIVKKLRDKTKKPTTAAHQAAQQLNLMAAAVAAQAEEAAKAAESDGDSIGSASDLRAEDDDLFDENPRQTQAKQRRPLPTEMDGISESVKTCSSSAYHAECESVTTHEDDVRSRVVVKVRMRKKDRALVTATGDPSAPSEELSPTSSDLLHKFGDRPLLLDDELDYGSGESKSSTESPVAPILPTNPDVQESEEDVFALAPFKLPVGVPLKRKTKPKAKPKPSEPEMWTSTPVKSAAVGDPSTNFASFPAQLTPTNNVGNSAQLDEFNEPIFNPFQENAQNTQSGETNQCDLFGLEPFPQVIRTIEQNPQHHQIHQFPSHNNNNNVIKVPASVSVALPASVPVSVSVNSSAPQLVTINHSIIINKTPEPPMNYNNNNNNQTAKSSGTSSVYVNVPSFSSMSTSSCSINQPQSSPAAVIPVQAPLPVPVPAPVSVPAVPVPIPAVVTHLRPLLPIADNAYVQISQDRCSDFTPDDEEEPVVLRDADVVADGIGIPTPAKPKKEKSNLAVRVLPGKLTQKVKGHSYKKVSAAALGSTSSLSSGSKQKHQRLQYQSHDDDDDEQDQDENRGAGGGRNFQSNTIQNSAKTGFSNMSFEDFPSDQEMDRLSRTIPFEVVRNEKMLLEAEKKFGSLKRRNNLFS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40494-1", "uniprot_id": "PRK1_YEAST", "id": "P40494-1", "name": "Actin-regulating kinase PRK1", "aln": "-------------------------MNTPQISLYEPG-------TILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRNFYLLRAMNQNANTQLAGEPSSTT------YVPTQKFIPVQSLQSINQP---------------------------------------------------PNMMPVTHVSTTPNLGT-------------------------FPISINDNNKTEVTAHAGLQVGSHSNLTSPLMKTKSVPLSDEFASLYYKELHPFQKSQTFKS-------------------------------------------------------------------------------------------VESFQSPQRKSMPPLSLTPVNNDIFDRVSAINRPNNYVDSETQT-------------------------------------------------------------------------IDNMAVPNLKLSPTITSKSLSSTKEIAAPDN---INGSKIVRSLSSKLKKVITGESRGNSPIKS----------------------------------------------------------RQNTGDSIRSAFGKLRHGFTGNSVNNSRSASFDNNNVNGNGNNTNRRLVSSS-----------------------------TSSFPKFNSDTKRKEESDKNQRLEKRRSMPPSILSDFDQHERNNSRTG---------------SRDYYRSHSPVKKTQASAKTTSKPTLIP-----------------------------------------DNGNVNINQEKKESIQRRVHNLLKSSDDPVTYKSASGYGKYTD-------------IGTETSNRHSSVRITPITEEKFKKTLKDGVLDIKTKSNGKDKSRPPRPPPKPLHLRTEIQKIRNFSRLQSKKLPIERISSEATETIVDVNVD--------DLEADFRKR---------------------FPSKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* ..: . ::.***: *: .. .***: * : .*: : *: * .:*:::.::*. . . **::** :*. :: ** :*: : * * *:*:.: :.:: :* :.*:****:*:**:* . * : :*****. *: . . *:.:* . ** .**:***::** * * *:****:* :***:*::: ** :* .* .. : *. .:** :: ** ** . **:* ** :: : *: *. . *. .: : * :. : . . . :. . . * : : : : . . . : : : .: . . . . : .. . . . : ", "identical_positions": 87, "similar_positions": 132, "identity": "5.8%" }, { "cls_id": "homologset.agr.SGD:S000001358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BRP7-1", "uniprot_id": "FDXA1_HUMAN", "id": "Q9BRP7-1", "name": "Ferredoxin-fold anticodon-binding domain-containing protein 1", "aln": "--------------MAPRRLLLVGEGNFSFAAALSETLDQSTQLTATCLQRPAELARDPLAWENLQCLRERGIDVRFGVDCTQLADVFELHEREFDQIYFIFPHCGRKAGVAKNRELLAKFFQSCADVLAEEGEVHVALCRGQGGTPADKPQREWHNSWQVVAMAALGGLILSDVYPFSCKAVAGYKCTGYRSQDKSFHVEGALNHIFTRSLPFEGSQPRIFRIKLGNQWFSFPEPEALVGKLNRGFLEAPSCHPIKTINEKLIAELGKVFPLKRLKCSYPLLPQEGTSVLPFWNCDFLSAAFWISLHEDNSNSESLTGGTSQDVEDFLVSFSELSLLKNPGRDGKEEACEGTCGQAKICLRPSLLVHVQDVIEVPDFLSGSLHILSGPVFQKCHILPFTMPAFHETLFILGVNQNLKDGCLQSLLDHLKGILDSLLTQTLP--------------------------------------------------------ESSK-----LSSLVKFVLQSNGKD------------YMIRVK----------------------------------------------------------------------------------------THNFSPD--------------------------------------------------------------------------------------CTEDLIIGSVITSATSVIHKDQCFVFVSMNLDLLAMLVWCISDWRMLWTFDNRFLKN-------------------------------------------------------------FVPGKIEPFKSHS-------------------------------LYPPCY-------VHDVS----------------------------------FWIDQKKGFDE-----------------------LEFHTVARAVSQDTIISIQFLSRFQHPKTQQVSLCYR--LTYQTCDKALTQQQVASMQSQFRKEIQQHLYVIPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UY23-1", "uniprot_id": "FDXA1_MOUSE", "id": "Q3UY23-1", "name": "Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog", "aln": "--------------MLPRRLLLVGEGNFSFAASLIDGLDPSVSVTATGFQHRAALEGDPVALENLKRLRERGVEVRFGVDCTQLSHALPADDRDFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAKAGEVHVTLCRGQGGTPADKPQREWHNSWQVVAMAALGGFILSDVCPFSCEAVPGYKCTGYRSQDRPFHIEGALTYIFTQSLPFESCQPRTFRVRLEDRWFYFTEPEALPGKLNRRFLEASSCHPIRTINEKLIAELGKTFPLKRLKCPLPLLSRGGPSVFLPATCDLLP-TFWIRLHEDNSCSEFQNGEITQEMEEIPVSVSECTLPESPVRDGCKGAQEGICGRVKLGLRPSLLVHVEAVIHSPDFLPASLHVLSGPVFRKCHILPFMMPAFHETLFILGFDNNMKESCLPSLLGHLKDALGNLLTQTLQ--------------------------------------------------------EGSS-----LGTSVEFVLQPNGKD------------YIIHVK----------------------------------------------------------------------------------------SLNFGPD--------------------------------------------------------------------------------------CAENLIIGSILTS-KIVKHKHQCFVFVSINLDLLVMLAYGISDWRILWTFDNRFLKR-------------------------------------------------------------FAPGKIEHFKSYS-------------------------------LYPPCY-------VHDVS----------------------------------FWVDEKKAFDE-----------------------LEFHTVARAVSQDTVVSVQYRDRFQHPETRQVSLCYR--LTYQTCDKALTPQLAAAMQSQFRKEIQRQLHVSPR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LJG1-1", "uniprot_id": "A0ABK0LJG1_RAT", "id": "A0ABK0LJG1-1", "name": "Mannosyltransferase", "aln": "MCALEIAVREPEEAMVPRRLLLVGEGNFSFAASLIDGLDPDVSVTATGFQHRADLEGDPVALENLRRLRERGVEVRFGVDCTQLAD-----EREFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAKEGEVHVALCRGQGGTPADKPQREWHNSWQVVAMAALGGLILSDVCPFSCEAVPGYKCTGYRSQDRPFHIEGALTYIFTQSLPFESSRPRTFRVRLEDRWFYFTEPEALLGKLNRRFLEAPSCHPIRTINEKLIAELGKTFPLKRLRCPLPLLSQGGPSVLPPVACDLLP-TFWICLHEDSSCSELLNGEITEDMEEIPDSGSECTLPKSPARDGCKAAQEGVCEQVKLRLRPSLLVHAEPVIHSPEFLPGSLYVLSGPVFRKCHILPFTMPAFHETLFILGFNRNTKESCLLPLLDHLKDTLGMASRRARQRLKGGGGGGGGSGGGSGSGGDAGPAAEKLRELLGSREAGVEPRPESGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLVAMTGWYMDKTPIAVLGVAAGAILGWPFSAALGLPIAFDLLAMKHRWKSFFLWSLAALVLFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFMIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSSWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPAHMNDQNREEPSRYIDISKCHYLVDVDTMRETPREPNYSSNREEWVSLAHRPFLDASRSSKLLRAFYIPFLSDQYTVYVNYTILKPRKAKQSRKKSGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40493-1", "uniprot_id": "BMT5_YEAST", "id": "P40493-1", "name": "25S rRNA (uridine(2634)-N(3))-methyltransferase", "aln": "----------------MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEK------------DETLMLCG-EGDFSFARSIVEQNYIESDNLIITSYDNSVNELK-------LKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGK-----GIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQG--YDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSE---QDTTKPAKE----------------------------------------RDARFYIFSKYVSNSSKHNRKSKKDTDSDSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *. .: .:* : :: * . : :* *:: .: . : . : ** :...: *.:: : : .. ::: : * : * : :.:.:* : : :: ** : . . : * :: :: . . . . : . : * : :: : * : * :: : *: . : *:.* * : *:. *. * . : * . * .. . . . : *:: . : : :* : * * :..:: * . :.: . ..: .... ", "identical_positions": 33, "similar_positions": 111, "identity": "3.13%" }, { "cls_id": "homologset.agr.SGD:S000001359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKJ1-1", "uniprot_id": "MAEA_RAT", "id": "Q5RKJ1-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VC33-1", "uniprot_id": "MAEA_MOUSE", "id": "Q4VC33-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L5Y9-1", "uniprot_id": "MAEA_HUMAN", "id": "Q7L5Y9-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSG--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------VWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXR3-1", "uniprot_id": "MAEA_DANRE", "id": "Q7SXR3-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQETAAQLSMALKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--FPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVN---------------VWKKKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERQE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFSQAEGGQLDEVRQVMGMLAFP-------SDTHISP---------------------------------------------------------YKDLLDPARWKMLIQQFRYDNYRLHQLGNNSVFTITLQAGLSAIKTPQCYK----EDGTS-----------------------KNPDCPVCSKSLNKLAQPLPMAHCANSRLVCK-ISGEVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVICPRTKEVFNFSQAEKVYIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40492-1", "uniprot_id": "FYV10_YEAST", "id": "P40492-1", "name": "GID complex subunit 9", "aln": "MAEKSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTAALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIKKRLEFFHELKDIKSQNSGTSHNGNNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSETKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWINENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNFTDLKLASGLLIFIKYCNDQKPTSSTSSGFDTEEIKSQSLPMKKDRIFQHFFHKSLPRITSKPAVNTTDYDKSSLINLQSGDFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLIYLSLGISSLKTRDCLHPSDDENGNQETETATTAEKEVEDLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHIQSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPG-QIMDPVDMKIFCESDSIKMYPT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. : .: :::: :::*** *.**:: :* *::**. : .* *:: :. : .:: : ::.*:. ::* .*:: : : *:*:*.::* .. :. . * :. : :: ::* * . ::*:.* : :** ::**:: :::* *:.:. ** :.. . ::* ::**. * * .* ***. *:**:***:: :: **: ::.: .:: ::: . *:* * . : *. * :*** ** :* : * * * :: :.:.. : : *. *:*::** :* : *:*.. * :*****.::: ::*.**:** :*:*. : * * :. : . . :.*:*:. . ::: * ::* *:: *:* ", "identical_positions": 95, "similar_positions": 163, "identity": "18.38%" }, { "cls_id": "homologset.agr.SGD:S000001365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K269-1", "uniprot_id": "A0A0G2K269_RAT", "id": "A0A0G2K269-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "MYACGQKRVS---------DPIADGSEPLWVLQIELSISGRTASRISRGRLANQIPPEILNSPQLQAAVHALPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTKAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPGS-SLALVSTIQFVSTLQAAAQELKAD----YHISVPQCKPLSPGEILGCTSPRLP-KEVEAVVYLGDGRFHLESVMIANPNIPSYRYDPYSKVLSR-EYYDHQRMQATRQEAIAAARSAKFWGLILGTLGRQGSPKVLEHLESQLRNLGLPFLRLLLSEIFPSKLSLLPSVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALK-EISWQQP--------YPMDFYAGSSLGPWTVNHGRDRAPRGLCQPASDKVQQGSRGHSPVPACEGCSCADQKATPPAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCQ5-1", "uniprot_id": "DPH1_MOUSE", "id": "Q5NCQ5-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "---MAALVVS---------ETAEPGSR-----------VGPGRGRISRGRLANQIPPEVLNNPQLQAAVQVLPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPGS-SLALVSTIQFVSTLQAAAQELKAD----YHISVPQCKPLSPGEILGCTSPRLS-KEVEAVVYLGDGRFHLESVMIANPNIPAYRYDPYGKVLSR-EYYDHQRMQATRQEAIAAARSAKSWGLILGTLGRQGSPKILEHLESQLRNLGLPFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALK-DISWQQP--------YPMDFYSGSSLGPWTVNYGRDRAPRGLCQPASDKVQQGSRGGSPAPACESCNCADQKATSPAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZG8-4", "uniprot_id": "DPH1_HUMAN", "id": "Q9BZG8-4", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "---MAALVVS---------GAAEQGGR-----------DGPGRGRAPRGRVANQIPPEILKNPQLQAAIRVLPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPAT-ALALVSTIQFVSTLQAAAQELKAE----YRVSVPQCKPLSPGEILGCTSPRLS-KEVEAVVYLGDGRFHLESVMIANPNVPAYRYDPYSKVLSR-EHYDHQRMQAARQEAIATARSAKSWGLILGTLGRQGSPKILEHLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGTAFPKPLLTPYEAAVALR-DISWQQP--------YPMDFYAGSSLGPWTVNHGQDRRPHAPGRPARGKVQEGSARPPSAVACEDCSCRDEKVAPLAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q567W6-1", "uniprot_id": "DPH1_DANRE", "id": "Q567W6-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "---MAASSSE---------LEVITAKK--------------PNVKGPR-RVANQIPEEILKDSDLNEAIKALPANYNFEIHKTIWRVRQAKAKRVALQLPEGLQMFACVIADIIERFTEADTLVMGDVTYGACCVDDFTARALGADFMVHYGHSCLIPIDS-TEGIKMLYVFVDIQIDTAHFLDTLRFNFPPGR-SLALVSTIQFVAALQAASAALKPD----YEVLVPQCRPLSPGEILGCTSPRLD-KHVNAVIYLGDGRFHLESIMIANPDTPAYRYDPYSKVFSR-EYYDHDAMRATRLKAIESACSAQRWGLILGTLGRQGNPKILEHLESQLKSLGRSFTRVLLSEIFPRKLELLADVD----------AQQWR----------YSRLDGRM-CIPWIS---------IPIRVWGPGLLIIRITNLNG-----LHAKPHRRLVSR--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTM2-1", "uniprot_id": "Q9VTM2_DROME", "id": "Q9VTM2-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "MLDVIQPSSN---------LPTSESTDIVVVR------ARPKKVFKPKARIN-RIPQELLDDPLLQQAIDRLPSNYNFEMHKTIWRIREMKAKRVALQLPEGLLMYAMVISDIVERFTSADTVIMGDVTYGACCVDDYTAKALGADLLVHYGHSCLIPVDQ-TCGIKVLYIFVDIKIDPLHFLDSVKLNFRPEVGQIALVSTIQFVTTLQAASTELKAAG---YDVIVPQAKPLSPGEILGCTSPQLP-ETTKMIIYLGDGRFHLESAMIANPLLKAYKYDPYEKKFTT-EQYDHSAMQNLRLDAVQRAKKARRIGIILGTLGRQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALFADIDAFVQIACPRLSIDWGSAFSQPLLNPYELSVVLG-DVEWTPHNSSPRNNAYPMDFYASGSLGPWTPNFKPPAIGECENKPSADCCGRCTRAELEKDDSGKAAALDDLLDFKKG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40487-1", "uniprot_id": "DPH1_YEAST", "id": "P40487-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "aln": "MSGSTESKKQPRRRFIGRKSGNSNNDKLTTVAENGNEIIHKQKSRIALGRSVNHVPEDILNDKELNEAIKLLPSNYNFEIHKTVWNIRKYNAKRIALQMPEGLLIYSLIISDILEQFCGVETLVMGDVSYGACCIDDFTARALDCDFIVHYAHSCLVPIDV--TKIKVLYVFVTINIQEDHIIKTLQKNFPKGS-RIATFGTIQFNPAVHSVRDKLLNDEEHMLYIIPPQIKPLSRGEVLGCTSERLDKEQYDAMVFIGDGRFHLESAMIHNPEIPAFKYDPYNRKFTR-EGYDQKQLVEVRAEAIEVARKGKVFGLILGALGRQGNLNTVKNLEKNLIAAGKTVVKIILSEVFPQKLAMFDQIDVFVQVACPRLSIDWGYAFNKPLLTPYEASVLLKKDVMFSEK-------YYPMDYYEAKGYG--------------RGETPKHAIE---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LFP2-1", "uniprot_id": "A0ABK0LFP2_RAT", "id": "A0ABK0LFP2-1", "name": "Esterase OVCA2", "aln": "----------------------------------------------------------------FKQGSSLSSQASSIICVQSIPGPSLPTPKASGCVFPKLCLLP-------LTLLSSPDSVLFSHLFLGPCSPEEQPR----------------------------GWWFSEEEADVFSALEEPTVCR-------------GLEAALETVAQALDKLG------------PFDG--LLGFSQGAALAAFVCALGQAGDPRFPLPRFIILVSGFCPRGLDHKEPILQSPISLPSLHVFGDTDRVIPSQESMQLASRFLGAVTLTHSGGHFIPAAASHRQAYLKFLDQFAE------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . .: ::: .* . :*: : : : : :::..: *.*. :: . : * . : :. : .::.:. * *:. :** :. : ** ** * :* . . * : : .: . : . :**:: . : . ", "identical_positions": 18, "similar_positions": 62, "identity": "3.77%" }, { "cls_id": "homologset.agr.SGD:S000001366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FHW6-1", "uniprot_id": "F7FHW6_RAT", "id": "F7FHW6-1", "name": "Protein SHQ1 homolog", "aln": "----------------MLTPAFELTQDRDFLTVAIRVPHARAS-------------------------EFDVYFEGVDFKFYAKPYFLRLT---------LPGRIVENGSEQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRK--------------SRSAKPLVEEIGASGVSEEGADDED-------EEFDWEIEQTPYEEVSESTLRSQCHYGFGNLRAGVVQRLQDELSEVIDIKDPDFTPVTERRQKRLAAELAKFDPDHYLADFFED----------EAVEQVLKYSPWWNDVHTEMMASLGKSQEQGDAAALVSFSEEEKYQLRK-FVNKSYLLDKTAHRQVYYSLVDILLAYCYEVRVTEGEHNVESAWTIRKLSPTLCWFETWTD---------------------VHEILVSFGRRVLCYPLYRHFKLVLKAYRDTLKILQLGKSAVLKCLLDVHKIFQENDP-AYILNDLYISDYCVWIQK--AKSK-KLAALTEALEAVSLSKAQLGFELLELE-AAAILVQEEETAGKTAQCSPTEQVPHSSPEPSDS---DSTSSSDTEDSAS--VQEELVGTQPSLLTSLQVPLLEEDSALTIRDSGLCRNMGSQKCEVRQGQ-----------PLASPR-----APLIEEVGDELKT-MLWVSTPSGVNAGSHRSVQDAKERDQVPCD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMX5-1", "uniprot_id": "SHQ1_MOUSE", "id": "Q7TMX5-1", "name": "Protein SHQ1 homolog", "aln": "----------------MLTPAFELTQDCDFLTVAIRVPHARAS-------------------------EFDVYFEGVDFKFYAKPYFLRLT---------LPGRIVENGSEQGTYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRK--------------SRSAKPLVEEIGASGVAEEGADDED-------EEFDWEIEQTPYEEVSESTLQSQCHYGFGNLRAGVVQRLQDELSEVIDIKDPDFTPVTERRQKRLAAELAKFDPDHYLADFFED----------EAVEQILKYSPWWNDAHAEMVASLGKNQEQGDSAALVSFSEEEKYQLRK-FVNKSYLLDKTAHRQVYYGLVDILLAYCYEVRVTEGEHSVESAWTIRKLSPTLCWFETWTD---------------------VHEILVSFGRRVLCYPLYRHFKLVLKAYRDTIKILQLGKSAVLKCLLDVHKVFQENDP-AYILNDLYISDYCVWIQK--AKSK-KLAALTEALKAVSLSKAQLGLELPELE-AAALLVQEEEGAGRAAQCNPSHQAPHSSPEPSDS---DSTSSSGTEDSAS--EQEEPAGTQPSLLTSLQAPLLEEDSALIIRESGLCRNMASQGCEVSQGQ-----------PLASAR-----APLIEELGDALK--MLRVSTPHGVSAGSHGSVEDAEERGQVPCD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PI26-1", "uniprot_id": "SHQ1_HUMAN", "id": "Q6PI26-1", "name": "Protein SHQ1 homolog", "aln": "----------------MLTPAFDLSQDPDFLTIAIRVPYARVS-------------------------EFDVYFEGSDFKFYAKPYFLRLT---------LPGRIVENGSEQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRK--------------SRTAKPLVEEIGASEIPEEVVDD---------EEFDWEIEQTPCEEVSESALNPQCHYGFGNLRSGVLQRLQDELSDVIDIKDPDFTPAAERRQKRLAAELAKFDPDHYLADFFED----------EAIEQILKYNPWWTDKYSKMMAFLEKSQEQENHATLVSFSEEEKYQLRK-FVNKSYLLDKRACRQVCYSLIDILLAYCYETRVTEGEKNVESAWNIRKLSPTLCWFETWTN---------------------VHDIMVSFGRRVLCYPLYRHFKLVMKAYRDTIKILQLGKSAVLKCLLDIHKIFQENDP-AYILNDLYISDYCVWIQK--VKSK-KLAALAEALKEVSLTKAQLGLELEELE-AAALLVQEEETALKAAHSVSGQQTLCSSSEASDSEDSDSSVSSGNEDSGSDSEQDELKDSPSETVSSLQGPFLEESSAFLIVDGGVRRNTAIQESDASQGK-----------PLASSWPLGVSGPLIEELGEQLKT-TVQVSEPKGTTAVNRSNIQER-DGCQTPNN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1R0-1", "uniprot_id": "SHQ1_DANRE", "id": "A1L1R0-1", "name": "Protein SHQ1 homolog", "aln": "----------------MITPAFELSQDADFLIVVIRVPYTRTS-------------------------DFDIYIQEEEFKFYAKPYFLRLT---------LPGRIVEDGREKASFDIDKGLFTLHVPKETAGQHFEGLEMLTSLLAPKG--------------SRSAKPLVEDSEACG---EGCEEED-------EEFDWQIEQEVYTEAPADTLKEYHKYGFGNLRSGVFSRLQEELNEVIDMKDPDNTNAELRRRNRLDTETAVFCADHYLVNLYEDK---------EEIRNLLKFKPWWRKLNPDPSAGYDIS---------MTFTEEEREQMRR-FTNRSYLLDKKARFHVWLGLVDIILAYVYDVRTTEGEHNVESAWTIRKLSGTLSWLETYHS---------------------VQDVLVSFGRRTYCYPLYRHFSLVTLAVKDAACIFQAGKACILKCLLAIHKIFRENDP-AYILNDLYITDYCIWIQR--VKSK-HVLALAEPLNNAKLQKNHLELELEIIEQAAELAVKEEEEKDTESDTDDSSSSSGDSDDEDDSDEECPEKAAEKKQTAFKAHAEAVTEAFCVELQRGDGRLIEELGKRLEEELTIEEDVPQERRSASEGEGERRREHYHPHAAESERDTTKAATGKELLDVCLQRKPLRILNTEELDSDDDDDDDDDGDLRITVVDERG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40486-1", "uniprot_id": "SHQ1_YEAST", "id": "P40486-1", "name": "Protein SHQ1", "aln": "----------------MITPRFSITQDEEFIFLKIFISNIRFSA-----------------------VGLEIIIQENMIIFHLSPYYLRLR---------FPHELIDDERSTAQYDSKDECINVKVAKLNKNEYFEDLDLPTKLLARQGDLAGADALTENTDAKKTQKPLIQEVETDGVSNNIKDDVKTIGQM-GEGFNWEIEQKMDSSTNNGILKT--KYGFDNLYDTVISVSTSNGNDINELDDPEHTDANDRVIERLRKENLKFDPEYYVSEYMTHKYGNEEDLEINGIKELLKFTPSIVKQYLQWYKDSTNPN----LVMPIEFTDEEQKQMQDNLPKKSYLVEDIKP--LYVTILSVLFSYVFEQIENEGTHTTESAWTMGKLCPQISFLDQQLKQVNELQDGMKEISKVNKDSSLIKIAIITGIRRALSYPLHRNYDLAMKAWTFVYYILRGGKRLVIRALLDIHETFRFHDV-YYVYDKVLLDDLTAWFIS--QGSENVIRSLALEMRKEQESLSKQDIEFECIASFNEQTGEPEWETLNIREMEILAESEYREQQQNPQ----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VI74-1", "uniprot_id": "SHQ1_DROME", "id": "Q9VI74-1", "name": "Protein SHQ1 homolog", "aln": "MLNGQIAHSYLENSCTLIIPRPPVLNQSSKSAQPAAAAAASSSAGEEFGQEAGSGLAEAEALHVDRIRNCDIFVDAHDLYFYADVKLYKFHSRRTFDLRELKTLLIKFNTTENHYQICLRCLPLTAGAQEGPGGERGGGGGTGDAAKQWN--------------SRKEYIAAFLHLPTLSANLPDKQPLVQEWKLKRITDQCQLQLDDHERTYKLTNNFGYGYASEYSGPLDLSELDR-ATCRVSEPHRMSPIQRRQERVVDEMKRFSREQYKINFVELQVP-------SGHQNPLRYKPKIYETS------------------MTQEQAHLLHNISRMQTREQQPCDVFRQNEIDCGLISILLAICYDVRTTNNEPTCESGWTRSILCPLYCYFEQFDN---------------------YRDVLVAFLRRMITYPLYRNFELGRQCVRDAIEVLKGGRNWLINQLLLTHQQFASSDPSRDSFNNYYLEDYIRYVTSPSACSDEHMRLLARNLKNVLMDVNKQHLGLGVTEIETELIKELMQEMRIDAGSQGSSPQQQHGDDDLDLDNDTSGQEDETT------TDDESVITDSFYSVDMDMRLIENEIVYEDDEEDEDDDEDGDDDEDGDGD--------------------------EDEDEDEDEDDSSSSTTTSSEAEGNSVIEQCSNSETAASTT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : :: . . * :: .: : *: . :: : ::. :: : : .. * * : : : : :. : : : : * **: . .. : :.:*. * :*: * * : * : . .: *::.* . . :: ... : : ::.:::: :: .:. . **.*. *. .::: . : ::: ** ***:*::.* . . ::: *: ::. ** *: * * :. : * :. *. : *: :. : : : : : ", "identical_positions": 36, "similar_positions": 118, "identity": "5.12%" }, { "cls_id": "homologset.agr.SGD:S000001368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7L9L4-1", "uniprot_id": "MOB1B_HUMAN", "id": "Q7L9L4-1", "name": "MOB kinase activator 1B", "aln": "MS---FLFGSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BPB0-1", "uniprot_id": "MOB1B_MOUSE", "id": "Q8BPB0-1", "name": "MOB kinase activator 1B", "aln": "MS---FLFGSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAQ1-1", "uniprot_id": "A0A8I6AAQ1_RAT", "id": "A0A8I6AAQ1-1", "name": "", "aln": "MS---FLFGSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921Y0-1", "uniprot_id": "MOB1A_MOUSE", "id": "Q921Y0-1", "name": "MOB kinase activator 1A", "aln": "MS---FLFSSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8S9-1", "uniprot_id": "MOB1A_HUMAN", "id": "Q9H8S9-1", "name": "MOB kinase activator 1A", "aln": "MS---FLFSSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3T1J9-1", "uniprot_id": "MOB1A_RAT", "id": "Q3T1J9-1", "name": "MOB kinase activator 1A", "aln": "MS---FLFSSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------SHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS-VAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q95RA8-1", "uniprot_id": "MOB1_DROME", "id": "Q95RA8-1", "name": "MOB kinase activator-like 1", "aln": "MD---FLFGSRSS--KTFK---------------------------------------------------------------------PKKNIPEG----------------------------THQYDLMKHAAATLGSG-NLRNAVALPDGEDLNEWVAVNTVDFFNQINMLYGTITEFCTEETCGIMSAGPKYEYHWADGLTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFHS-SAKTILKRLFRVYAHIYHQHFTEVVTLGEEAHLNTSFKHFIFFVQEFNLIERRELAPLQELIDKLTAKDERQI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BSU7-1", "uniprot_id": "MOB3A_MOUSE", "id": "Q8BSU7-1", "name": "MOB kinase activator 3A", "aln": "MSNPFLKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKRAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRINLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEQRFRKPTALSAPRYMDLLMDWIEVQINNEDIFPTNVGTPFPKTFLQ-AVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVTEFNLIDPKELEPLKEMTSRMCH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEX8-1", "uniprot_id": "B5DEX8_RAT", "id": "B5DEX8-1", "name": "", "aln": "MSNPFLKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKRAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEQRYRKPTALSAPRYMDLLMDWIEVQINNEDLFPTNVGTPFPKTFLQ-AVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVTEFSLIDPKELEPLKEMTSRMCH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BX8-1", "uniprot_id": "MOB3A_HUMAN", "id": "Q96BX8-1", "name": "MOB kinase activator 3A", "aln": "MSNPFLKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQ-TVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VE04-1", "uniprot_id": "MOB3B_MOUSE", "id": "Q8VE04-1", "name": "MOB kinase activator 3B", "aln": "MS-IALKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKRAQASLNSGVDLRAAVQLPNGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEDIFPTCVGVPFPKNFLQ-ICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTTRMCH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L8S1-1", "uniprot_id": "A0ABK0L8S1_RAT", "id": "A0ABK0L8S1-1", "name": "", "aln": "MS-IALKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKRAQASLNSGVDLRAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEDIFPTCVGVPFPKNFLQ-ICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTTRMSD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TA1-1", "uniprot_id": "MOB3B_HUMAN", "id": "Q86TA1-1", "name": "MOB kinase activator 3B", "aln": "MS-IALKQVFNKD--KTFR---------------------------------------------------------------------PKRKFEPG----------------------------TQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQ-ICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJG4-1", "uniprot_id": "MOB3C_MOUSE", "id": "Q8BJG4-1", "name": "MOB kinase activator 3C", "aln": "MA-LCLKQVFAKD--KTFR---------------------------------------------------------------------PRKRFEPG----------------------------TQRFELYKKAQASLKSGLDLRSVVRLPPGESIDDWIAVHVVDFFNRINLIYGTMAEHCSESSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEDVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIQEFSLVDQRELEPLREMTERICH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP72-1", "uniprot_id": "D3ZP72_RAT", "id": "D3ZP72-1", "name": "", "aln": "MA-LCLKQVFAKD--KTFR---------------------------------------------------------------------PRKRFEPG----------------------------TQRFELYKKAQASLKSGLDLRRVVRLPPGESIDDWIAVHVVDFFNRINLIYGTMAEHCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEDVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIQEFSLVDQRELEPLREMTERICH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70IA8-1", "uniprot_id": "MOB3C_HUMAN", "id": "Q70IA8-1", "name": "MOB kinase activator 3C", "aln": "MA-LCLKQVFAKD--KTFR---------------------------------------------------------------------PRKRFEPG----------------------------TQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQ-VCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL13-1", "uniprot_id": "MOB3_DROME", "id": "Q9VL13-1", "name": "MOB kinase activator-like 3", "aln": "MALNGFLEFFQKG--KTFR---------------------------------------------------------------------PKKPFASG----------------------------TIRYSLHKQAQASLQSGINLRQVVRLPQGENLNDWLAVHVVDFFNRINLIYGTVSEFCNETTCPTMSGGSRYEYLWADGDLYKKPTALSAQKYIEHLMDWIETQINNEAVFPVSTDVPFPKNFIA-ISRKILTRLFRVFVHVYIHHFDRIVSIGAEAHVNACYKHFYYFVQEFDMISAKELEPLQEMTSRICKDKD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40484-1", "uniprot_id": "MOB1_YEAST", "id": "P40484-1", "name": "DBF2 kinase activator protein MOB1", "aln": "MS---FLQNFHISPGQTIRSTRGFKWNTANAANNAGSVSPTKATPHNNTINGNNNNANTINNRADFTNNPVNGYNESDHGRMSPVLTTPKRHAPPPEQLQNVTDFNYTPSHQKPFLQPQAGTTVTTHQDIKQIVEMTLGSEGVLNQAVKLPRGEDENEWLAVHCVDFYNQINMLYGSITEFCSPQTCPRMIATNEYEYLWAFQ-KGQPPVSVSAPKYVECLMRWCQDQFDDESLFPSKVTGTFPEGFIQRVIQPILRRLFRVYAHIYCHHFNEILELNLQTVLNTSFRHFCLFAQEFELLRPADFGPLLELVMELRDR-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :*:: *:: : : .: : . :* : *. .* ** **. ::*:**: ***:*::*::**:: : *. :* * . .*** * : * .* :*: ** * : :::* :** .**: * ** *****:.*:* :** : : :: :*:.::** * *: :: :: ** *: .: ", "identical_positions": 58, "similar_positions": 66, "identity": "17.96%" }, { "cls_id": "homologset.agr.SGD:S000001370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VXV2-1", "uniprot_id": "Q9VXV2_DROME", "id": "Q9VXV2-1", "name": "Zinc metalloproteinase YIL108W", "aln": "MSSGTAGCKRAHSIEVEQPLTSERLEHSLLLVKGRLVPKCSTARQLKAILDLPEHLSQEQLTQLSAGGEFKLLFDLEQANREEEEEESACLLELRSCTATRTISFSYRPRRSSYRVQPLYLLCQDEEKTLAQQHEVHSLIDLNLRLVQSIYAHKLHAAGFPNRTFTLNGKC---CAFRSQLTR---KQALAKSEDELWQHFAGEIIACPQWGHQLLLKFVAFVGCTRYDGDAVVASGDSSYANIR--------RHLKGHAALGGGG----LALFGSAHFYAWPTSFAEIGDCVRSAQRVDIARLPDESNYRRTYGGVYASTLGAVCHELGHCFDLGHTSEGVMGQGFDYLNR----------------------------------VLTVDQPTEHLPQRIVD------ARRGSLANTNSSEG--GSSSSSSTSSS---------------------SSSAGSG---------------------AATGNRARLTKLKLQPSSQLLDNYHNQRRHDSFYFARN---------------------------------CAVILAHHRWLN-----LELEQTAAVDFEAASIQLNRDTREIRSSRPIRLIELRCNQNSLVAHYEEFEEPYVHRFQLPASLWHLLAEQCTHYVFVLTTSGDTKRLSCDSS---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40483-1", "uniprot_id": "YIK8_YEAST", "id": "P40483-1", "name": "Putative zinc metalloproteinase YIL108W", "aln": "-MVGSKDIDLFNLRENEQIVSPCLIVHGKCNKQNGAKTVQVQHPQLPPIT-YPIHNQFFKATVILTPGENKLTFVTDTNTARTIVCYYTPLTQNPPVHLCLILAKDSPLQFDSPREQ------KDREGGNGLELAIKKLR-LGARLMQAYTNEQMLRNSMGNRTFPFVEEFTWDTLFERPAMRNTIKIHVVRSEKTVKEIQDPDIAQQNSKGKNTGALFGIAMDALKSYGGPFTNNEKPVQAACMFLDTHWDGKLIRGHAALGGGDDSIKLAIFGSHGLYSWPTCLEQLVPYFTDETRSSTSEVANDCNECGTYWECLTITLGAFMHEIGHLLGCPHQESGVMLRGYTTLNRSFLTKEAYSVRTNSTGASPPIFPKEECTWNRLDTVRFLYHPSFTLPQDYYDPSFMRPTKLGGYPNIKHSVYPLGNGSCRILSPTGIYLIEIICDDLARGHIEYLPVSLGGQGPQREVIVTLDDLRARLPKNELAKFGNTFKLKILSVNAPETEFDKFPSLLDVQPLDMSKYGFSKNVQGIKSPLYGRSDGGNAVGVVAFDVRLVTAVRIYHGYALDGVRFYYKEKPTGTKDAPASKPSVPPRNYFSKITHSIKNHASINEENLKSVLFGHETQNFTDATLEPGEIIIGFNLRCGAWVDAIQIITSHGRMTDMFGNKDGGGFAELQPPNGQYILGVTGRVGQWVDAFGIIYGAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . : * ** ::. : *. :. . ** .* * * . : * : : ** ** * : . . : * : . :: . : .* * * :*.* . : ::.* *. **:*: .:: .: ****.: : *. * * :.:**. : : :* . *:: * :.. : *.... . .. * : ::********. **:*** :*:***.: :: . . * . :.:.::.* ** : ****. **:** :. * ..*** :*: *** * : :*: *** * :: *. .* : * *..*. *.: * .*.* * ** :*. *.::... :*:: . :.: ::: ** : * *: : : *.: * *:. .: . : ::.*: ::* . : . : :.. *..: : :* :* .: . *:: . ", "identical_positions": 112, "similar_positions": 168, "identity": "15.89%" }, { "cls_id": "homologset.agr.SGD:S000001371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZA8-1", "uniprot_id": "D3ZZA8_RAT", "id": "D3ZZA8-1", "name": "", "aln": "MAQPRIPAARGAAAGLQAQNGAASA------------SGSPYTNGPVQHTLMSSQVSLSQGYDSQLPG-----------------------SYPHPMPAKTLNPFSAQSNYGGSQGSG----------------QALNSPLVTSSPVPPSLHSGPVPRMALPTSQNPAATPMP---------------SGSFPPGTNPAPPLNWQYNHPSTGPQTNHFP-HVAQPTIPGNTDFTADH-------------------------------PYVSSGDPALQTS---FKKPG-SALPLQN--------------------PPLPPTFQP----GAPP----GPPPAGGPP--PSRGPVPQK---------------------------------------------------------TPPRAAFPPSLNSAVNQEG---------ITSNANTG-SAAHSTYDEIEGG---------------------GFLATPQLVNQ-------NPKTSRSVGYAYP--SLPPGYQNTAPP-VAGMPPSSLN--YPSGPQAFTQAPLGANHLTASMSGLSLH----PEGLRVVNLLQERNMLPSTPLQPPVPNLLEDVQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFK----DLVQLPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSL-------QEGLSQPQMLIVSDIDDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKFQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSS--VLSSQQ-PGLMVPFSLRLFPLFVLALLKQKSFQTGTNVRLDERIFAMCQVKNQPLVHLMLTTHPSLYRVDNLSDEG-----ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGRNCAQNFLSQVLGVQNYASIPQTMTDLPELDTPES-ARMTAFISWLR--EQRPFFPILYVIR--------------EESLMKAAFLQNLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2P1-1", "uniprot_id": "SC24A_MOUSE", "id": "Q3U2P1-1", "name": "Protein transport protein Sec24A", "aln": "MAQPRIPAARGAAASLQAQNGAASA------------SGSPYTNGPVHNTLMSPQVSSSQGYDSQPPG-----------------------SYPRPMPAKTLNPFSAQSNYGGSQGSG----------------QTLNSPLVTSGPVLPSLHSGPVPRMPLPTSQNPAATPMP---------------SGSFLPGANPPPPLNWQYNYPSTGPQTNHFP-HVAPPTLPGNPNLTADH-------------------------------QYVSSGDPALQTS---FKKPG-SALPLQN--------------------PPLPPTFQP----GAPP----GPPPAGGPP--PSRGPAPQK---------------------------------------------------------TPPRAAPPPSFNSAVNQEG---------ITSNANNGSTAAHNTYDEIEGG---------------------GFLATPQLVNQ-------NPKTSRSVGSAYP--SLPPGYQNSAPP-VAGMPPPSLS--YPSGPQAFTQTPLGANHLTASMSGLSLH----PEGLRVVNLLQERNMLPSTPLQPPVPNLLEDIQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFK----DLVQLPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSL-------QEGLSQPQMLIVSDIDDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSS--VLSGQQ-PGLMVPFSLRLFPLFVLALLKQKSFQTGTSIRLDERIFAMCQVKSQPLVHLMLTTHPSLYRVDNLSDEG-----ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSLLMLWVGRNCSQNFLSQVLGVQNYASIPQTMTDLPELDTPES-ARIAAFISWLR--EQRPFFPVLYVIR--------------EESLMKAAFLQSLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95486-1", "uniprot_id": "SC24A_HUMAN", "id": "O95486-1", "name": "Protein transport protein Sec24A", "aln": "MSQPGIPASGGAPASLQAQNGAALA------------SGSPYTNGPVQNALLSSQESVSQGYNFQLPG-----------------------SYPHPIPAKTLNPVSGQSNYGGSQGSG----------------QTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMP---------------SSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNH-------------------------------QYVSSGYPSLQNS---FIKSGPSVPPLVN--------------------PPLPTTFQP----GAPH----GPPPAGGPP--PVRALTPLT---------------------------------------------------------SSYRDVPQPLFNSAVNQEG---------ITSNTNNGSMVVHSSYDEIEGG---------------------GLLATPQLTNK-------NPKMSRSVGYSYP--SLPPGYQNTTPPGATGVPPSSLN--YPSGPQAFTQTPLGANHLTTSMSGLSLQ----PEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQK-LNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFK----DLVQLPVVTSSTIVRCRSCRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYGL-------QESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSSAKDI-HMTPSTD-FYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSS--VLSNQQ-PGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEG-----ALNIS---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPES-ARIIAFISWLR--EQRPFFPILYVIR--------------DESPMKANFLQNMIEDRTESALSYYEFLLHIQQQVNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSG8-1", "uniprot_id": "A0A8M1PSG8_DANRE", "id": "A0A8M1PSG8-1", "name": "", "aln": "MSSGQFAPQNGAGDSFA--NGPSQN------------AVYPLNPGFMAPPLQPGYISSVPAKGLPAGP-----------------------QSCYNTHRHQPSPVGTHSPLPASPNHR----------------PVLPGPPQAS-PTPPPHANSHYQHTQQPSSWSSTAAVFQ---------------STAAPPALNVMAPH--QTFGPPPAAMRGTPPLTVPPPTVAP-PPFAAAP-------------------------------PPSTIAPPPFAAA---PPPSTIAPPPFAA--------------------APPPSTIAPPPFVAAPPPSTIAPPPFAGAP--PTSTVLPP-----------------------------------------------------------PRAGVPPPSASAAVPPPP---------TGAHSDAGPYHLGQMSRPVGSG---------------------YPSLQPGYSTA-------QGYTPPVGQIQHPPGQIQPSSMGQIHP-TAQIPPPSAGQFHPAGQIPPSAQQAGLSPSLAALSLQSHT----PEALRVLNLLQERNLLPHTAVTPPLPCLPQDLQR-MNCSPEVFRCTLTSIPQTQALLNKAKLPLGLLLHPFK----DLSQLPVVTSSNIVRCRSCRTYINPFVTFVGP-TRWKCNLCHRINEVPEEFMYNPVSKSYGAPHKRPEVQNATIEFIAPSEYMLRPPQPAVYLFVLDVSHNAVETGYLDAVCRSLLDNLSSLP-GDARTKIGFITFDSTIHFYSL-------QEGLSRPQMLIVSDIDDVFLPTQDGLLVNLNECKELVQDLLSSLPQMWRQTMETHSALGPALQAAFKLLSATGGRISLFQTQLPTLGIGALKPREQPSTKTQAKDIQHLSPATD-FYKKLALDCSGQHVAVDLFLLSAQYCDLSSLGCISRYSAGSVFYYPSYHTLHNPAQAERFQKDLKRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLANVNPDAGFAVQMNIEENLLDLQTVSFQAALLYTSSKGERRIRVHTLCLPVVNSLSDIFAGADVQAITALLASMAVDRSVTASVSDARDALVNAAVDMLSSYRSS--VLTVPQ-PGLLAPACLRLFPLYILALLKHKAFGTSSATRLDERMFCMCQLKQQPLAYAMLSIHPSLYRVDDLTDEG-----ALNVN---------DCTIPQPRVQQLSVEKLSRDAAFLMDCGSVLYLWIGRNCNPAFLTQVLGVDGYANIPLNMTQLPELDTAES-CRMRAFVDWLR--ERRPFHPLLHVIR--------------DESPLKAEFLQLMIEDRSESALSYYEFLLHLQQQSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95487-1", "uniprot_id": "SC24B_HUMAN", "id": "O95487-1", "name": "Protein transport protein Sec24B", "aln": "MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPS--------QQHHQQQSLSGYSTLTWSSPGLPSTQDN---LIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQ------------------------------------------QKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYP--TLQPGYQNATAPLISGVQPSNPV---YSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKK-LNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFR----DLTQLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNL-------QEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGST--VSNLQH-SALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEG-----AVHVN---------DRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSS-ERARSFITWLR--DSRPLSPILHIVK--------------DESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LR69-1", "uniprot_id": "A0ABK0LR69_RAT", "id": "A0ABK0LR69-1", "name": "", "aln": "MSAPAGSPHPAAGARMPPKLGGAVS-----------GLAPPQQNGPAQSQMQVPSGYGLPHQNYMAPSGHYSQGPGKMTSLPLDNQCENYYSRPYTAPTQNVGTPSSANQPGAQLMYGRGPSAPHMGASMPGPFQGAPASASHSYPSASQPYSSLGNRYSSPATYSATASVASQGYPSTCSHYPISTVSNVVYPNVSYPSLPASEPYGQMFTSQSAPPPARPLKESYSGPSTAVAYPSRPPPPPSQHQQQQQQQQQQQQQSHSGYSSLPWSGPGLPPAQDS---LIRNQMGSLAIPNSHPAIN----------ENVQPPKPSSVVATVLPGPS---STRMPPAPSHPVGPVPSAPPPPEQMQTKVRFPVPSHAGCGKWRPVNRDPGLWGTYIGRMRERPPEKFANKGMQYGDYVNNQASSTPTPLSSASDDEEEEDEDEEAGVDSSSTTSSASPLPNSYDALEGGSYPDMHSSSASSPVPDRAPEPNSTLVPTPTAA------QPAKVAKPFGYGYP--TLQPAYQNAAAPPTT-AHPSGPA---YSG---YPQQYPGVHQLSSGLGGLSLQSSPQPESLRPVNLTQEKNILPATPIWAPVPNLSAELSK-LNCSPDSFRCTLTSIPQTQALLNKAKLPLGLLLHPFR----DLTQLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFLYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTVLCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNL-------QEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVHHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIFYYPSFHSTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLADTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDPLSAYSSA--VSSVPR-STLTAPSSLKLLPLYVLALLKQKAFRTGTSTRLDDRVYAMCQMKSQPLVHLMKMIHPNLYRIDRLTDEG-----AIHVN---------DRVVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWIGKGCDSNFIENVLGYPDFGSIPQKMTHLPELDTLPS-ERTRSFVTWLR--DSRPLSPVLHVVK--------------DESPARTDFFQHLVEDRTEAALSYYEFLIHVQQQVCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z813-1", "uniprot_id": "A1Z813_DROME", "id": "A1Z813-1", "name": "", "aln": "MSTYNPNFVPPAHAPMPLNGNNFVNG---------VQGSVQQQPGPPPGQQYIPQKQPQQFQQPPPAAAFPGAG----------------APGNVPPPQQFNSGITNQFLPPTSGAATPLQQLPPSTLPPHLRPPAANGPPLTNGSNGASSANSSRTASPRPVGAAPQYAQGP------------IAAALNNPPLASGLRPSPQPTHQSLANLTSNLENLNLNTTRANGGTSILPQPQTQQQYAP-------------TVTQKDGRGVASAQTGPPQFNDANSLLAASGVAAALVPNAMATPFS-----------GQKPPNLAPNPAKMFGSASMAGRPTPAGQRIPYGVPPPTNPEQQSQQ----------------------------------------------------NNNLQNAPPPPRVGAVWPPS---------LPNVAAPGAQPMMPPAQQTPQTYP------------------YSQVYQPGPQQQ--------PPPPQSAVQPPPPGMFGTQPTGAPLQYQAQAPPQAYG----QHPQQAPQTAPGGPYGTTAPLNVAQQGFSRLWGQDTIDLMQNRHILTPATLPPPKVVLHNQFHESINCSPSIMRCTLTKIPESNSLLQKSRLPLGIVIHPFR----DVNSLPVIQCINIVRCRLCRTYINPFVYFVDS-KMWKCNLCYRVNELPDDFQFDPATKTYGDVTRRPEVRSSTIEFIAPSEYMLRPPQPAMYLFLFDVSIIAQQSGYLEAACAVLNRHLDEMP-GDARTQVGFICFDSFVHFYSM-------AEGLNQPHEMTLLDIEDPFLPRPDSLLVNLKECKELVRDLLKQLPKRFAHTHDPGSALGAALQVAFKLMQASGGRITVFQSCLPNKGPGALEPREDPNNRS-AKDVAHLNPATD-FYKRFALECSGYQIACDLFLMNQQYSDMATISGISKHSGGCVHHFPLYQKTK-PHMVESFRSCFKRYLTRKIGFEAVMRIRCTRGLQVHTFHGNFFVRSTDLLSLPNVNPDAGYGMQISYEESLTDAKTICFQAALLYTNSEGERRIRVHTVCLPVTASLPEVMHSADTEAIIGLLSKMAVDRSVASNLSDARDAFINATIDVYNAFKIAQNLPSGQS-GQLIAPRSLALLPLYILALLKHPAFRVGTSTRLDDRVYAMDCMKTLPLDQLMKYVYPELYKIDALIYHAR----NSNISSNQDDDEDEDEPLPELPRLQLSAEHLDSRSIFLMDCGTLIMIYVGLNVPPDVLEAVLGISSTAELGDYVYGLPNVVSNEN-DVLKRFILRLN--YDKPYSALVQIIR--------------DTSTAKGQFTERLTDDRSESSLSYYEFLQHIRAQVK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40482-1", "uniprot_id": "SEC24_YEAST", "id": "P40482-1", "name": "Protein transport protein SEC24", "aln": "-------------------------------------MSHHKKRVYPQAQLQYGQNATP-----------------------------------------------------------------------------LQQPAQFMPPQDPAAAGMSYGQMGMPPQGAVPSMGQQ-----------------------QFLTPAQEQLHQQIDQATTSMNDMHLHNVPLVDPNAYMQPQ-------------------------------VPVQMGTPLQQQQ-------------------------------------------------------QPMAAPAYGQPSAAMGQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPMNQLYPIDLLTELPPPITD----------------------------------------------LTLPPPPLVIPPERMLVPSELS--NASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPK-SRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDSENNEESADQINMMDIADLEEPFLPRPNSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKN-PNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMAD-YCYVQVAVLLSLNNSQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVP-SDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPVQTE--------DGEATGTIVLPQPINATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . * . . * .. * : . : * : . . : .* * . *..*. :*.**. :*:..:**:*::**:*::::*:: *: *: ***** **:*:**** *: *:**:* *::* :: . . * *:: :.:*::*..:* ** * *. * *::*** : ::* * * :*. :* : **::.:: .*. :*:: : *. .: : : : *::: *:* :.::*.* .:: :. **. :*: : . . ***.**: *::*: **:: :.. **. * * *: *::.. . :* :: .. * ***.::::** : : **** . :* *::::. :*:.:.* ..:* : : * : . : :::: .: :*:*** * : ** : *:*:** **:** ::..: * .: .::. :*.: .* *:* : .:.:****: *:.:*.. :* :: ..* * : . **:::: :.:.*** : ::. * :: : . * * ::** : :* *: :* . *.* .: :: ** : :*.:* :. : .. : : : . : . :*:* *. : :::* . .: *:* . .: :* : . :: *. : ::: : : : . : :*: ** *** :: : ", "identical_positions": 166, "similar_positions": 281, "identity": "12.07%" }, { "cls_id": "homologset.agr.SGD:S000001372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM84-1", "uniprot_id": "MET18_RAT", "id": "Q4KM84-1", "name": "Histidine protein methyltransferase 1 homolog", "aln": "MAFQFNFSIEEDLENKLTSLDDGTCVLKS---------QKGKE-DKNQSTELPGLPQDRLWKCSSLGSAASSEDTDSPPSTADRSGVPEACEKQPSLKPAKEHVIPKDCDQVLENKVLEMLPGSQHVSTAVVKTISLKEKFPGENIVSQSFSSHSDLIPGVYEGGLKIWECTFDLMTYFTKAKVK--FAGQKVLDLGCGSGLLGITAS--------KGGAREVHFQDYNGLVIDEVTLPNVVANVPLQ--------------------GDSNGINEPAGKRQRKSEVAQETCKCRLFSGEWAEFCKLVLS-EKLFVKYDLILTSETIYNPDYYSTLHETLLRLLSR---NGRVLLASKAHYFGVGGGVHLFQKFVEEKG----VFETRTLEVIDEGLKRFLMEMTFKCPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZ09-1", "uniprot_id": "MET18_MOUSE", "id": "Q9CZ09-1", "name": "Histidine protein methyltransferase 1 homolog", "aln": "MAFQFNFSIEEDLENKLTSLDDGTCVLES---------QKGKQ-DKRQSTERPGLPRDHSWKCSSLGNAASSEDTGSPPPIADRSDDPEACKHQPSWKPAKEHVMPKDVNHVLENTVLEMLPGPQHANTAVVKTVSLKEKFPGENIVSKSFSSHSDLIPGVYEGGLKIWECTFDLLTYFTKAKVK--FAGQKVLDLGCGSGLLGITAS--------KGGAREVHFQDYNGLVIDEVTLPNVVANVPLQ--------------------DDSNGKNEPDGKRQRKSEVGREICKCRLFSGEWAEFCKLVLR-EKLFVKYDLILTSETIYNPDYYSTLHETFLRLLSR---SGRVLLASKAHYFGVGGGVHLFQKFVEEKG----VFETRTLEVIDEGLKRFLMEMTFKHPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95568-1", "uniprot_id": "MET18_HUMAN", "id": "O95568-1", "name": "Histidine protein methyltransferase 1 homolog", "aln": "MTFQFNFTIEDHLENELTPIRDGALTLDSSKELSVSESQKGEERDRKCSAEQFDLPQDHLWEHKSMENAAPSQDTDSPLSAASSSRNLEPHGKQPSLRAAKEHAMPKDLKKMLENKVIETLPGFQHVKLSVVKTILLKENFPGENIVSKSFSSHSDLITGVYEGGLKIWECTFDLLAYFTKAKVK--FAGKKVLDLGCGSGLLGITAF--------KGGSKEIHFQDYNSMVIDEVTLPNVVANSTLE--------------------DEENDVNEPDVKRCRKPKVT-QLYKCRFFSGEWSEFCKLVLSSEKLFVKYDLILTSETIYNPDYYSNLHQTFLRLLSK---NGRVLLASKAHYFGVGGGVHLFQKFVEERD----VFKTRILKIIDEGLKRFIIEITFKFPG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQK8-1", "uniprot_id": "Q9VQK8_DROME", "id": "Q9VQK8-1", "name": "Histidine protein methyltransferase 1 homolog", "aln": "-MFKFNFDVKAESSEDPEAVKNDIFSKQE-----------------NSEERESGITKDIDWYNS---------------EKVQPLDNLISAMDFYELNAKEMEVGKMTIKHLVAGFLLEDLKEQSHLVNLDLR---------------KSEENHSDLISGVYEGGAKIWECTEDLLLYLSEKYEDSFWKEKRVLDLGCGCGLLGIYAM--------KHGAR-VDFQDYNKDVLEYITYPNILLNLDDS--------------------LSEDE------------KLKFLDNSTTLYSGDWSHFAELSRD----VAKYDLILTSETIYNIANQQKLLDTFAGRLKS---DGVILVAAKSHYFGVGGGLEQFSENIRLGN----VFQSESVWQADENLKRGILQLKFK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40481-1", "uniprot_id": "HPM1_YEAST", "id": "P40481-1", "name": "Histidine protein methyltransferase 1", "aln": "MSFSFGFTSNDFDDDELVAQPETFVESSK----------------ENENTTAYINPLDSDFLSQAGVVQPNVEDLGTILESLKDVRLTFEEFQSPIYRKPLIKRELFDVKHQLMLETDAQSNNNSTELDILLG------------------DTSEDLRKNIYEGGLKSWECSYDLVDLLSENVDRISNDIDAVVEIGCGTALPSEFLFRSALLRNDRSKGLKFVLTDYNASVLRLVTIPNLVITWAKTVLTKEQWYALQKDECEDIPINNEELLLTSKLLAAFYDDVQSRNISVTLISGSWGRKFSNLIHEVLSGSQKVLSLSSETIYQPDNLPVIAETILDIHNLPQTDVKTYVAAKDIYFGVGGSITEFEAYLDDKINSEHLPIHSERFKVNSGLKRSIICIETNKAIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*.* : .:. . : .. . . . * : . . . . . .: : . : .. .** .:**** * ***: **: ::: . *:::*** .* . : . . : *** *: :* **:: . ..: .: . : **.*.. . : * *:*****: : :*: . . :*:* ******.: *. : : :..*** :: : : ", "identical_positions": 51, "similar_positions": 82, "identity": "12.41%" }, { "cls_id": "homologset.agr.SGD:S000001373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10888-1", "uniprot_id": "COX41_RAT", "id": "P10888-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---MLATRALS--LIG---KRAISTSVCLRAHGSVVKSEDYA------LPSYVDRRDYPLPDVAHVKLLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNES-FAEMNKGTNEWKTVVGLAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKVNPIQGFSAKWDYNKNEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19783-1", "uniprot_id": "COX41_MOUSE", "id": "P19783-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---MLASRALS--LIG---KRAISTSVCLRAHGSVVKSEDYA------FPTYADRRDYPLPDVAHVTMLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNES-FAEMNRGTNEWKTVVGMAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKANPIQGFSAKWDYDKNEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13073-1", "uniprot_id": "COX41_HUMAN", "id": "P13073-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---MLATRVFS--LVG---KRAISTSVCVRAHESVVKSEDFS------LPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKES-FAEMNRGSNEWKTVVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6I1-1", "uniprot_id": "F1R6I1_DANRE", "id": "F1R6I1-1", "name": "Cytochrome c oxidase subunit 4", "aln": "---MLSSRALVRGLQSGFWRRLSTSSGIWAAHTHDVDVTDCS------VPQYNNRLDTPLPDVPFVRNLSAEQKKLKEKEKGPWTQLSKEEKLAIYRLTHELS-FPEMRKGSKEWMTVLAGVFFFLGFTGLLVWWQRVFVYGDVPHTLSQEWIEKQTQRMLDMKVNPITGFAHKWDYEKKQWK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91W29-1", "uniprot_id": "COX42_MOUSE", "id": "Q91W29-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRAARSLVMRTG-LRTRGTGTHSPGDAAGS-QRRMTP------YVDCYAQRSYPMPDEPFCTELSEEQRALKEKEKGSWTQLSQAEKVALYRLQFHET-FAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLAAHWDYEKKEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y94-1", "uniprot_id": "COX42_RAT", "id": "Q91Y94-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRATRSLVMKTGGLRTQG--THSPGSAASSSQRRMTP------YVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHET-FAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KJ9-1", "uniprot_id": "COX42_HUMAN", "id": "Q96KJ9-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MLPRAAWSLVLRKGGGGRRG--MHSSEGTTRG-GGKMSP------YTNCYAQRYYPMPEEPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNET-FAEMNRRSNEWKTVMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDMKVNPVQGLASRWDYEKKQWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIQ8-1", "uniprot_id": "Q9VIQ8_DROME", "id": "Q9VIQ8-1", "name": "Cytochrome c oxidase subunit 4", "aln": "MALRLLNSAVLRQLASQLPKSAQVGSVAAVHTLDKIGKREIVGYGWNGTACYADRVDYPLPAVRFREPTN-EINALRAKEQGDWKKLSTQEIKALYRASFCQT-IAEVQAGSGEWKLHLGVSLLFCAAAIWVAVLMNIFVYDELPVTFDEEHQKAQLQRIIDLEINPVTGLTSKWDYENKKWKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00425-1", "uniprot_id": "COX5B_YEAST", "id": "P00425-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "---MLRTSLTKG-------ARLTGTRFVQTKALSKATLTDLP------------ERWENMPN----LEQKEIADNLTERQKLPWKTLNNEEIKAAWYISYGEWGPRRPVHGKGDVAFITKGVFLGLGISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGGYSQVQSK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* . * ::: * *. * : . . . : :: . : : . . :: : . : : . : ** * : . ", "identical_positions": 8, "similar_positions": 30, "identity": "4.35%" }, { "cls_id": "homologset.agr.SGD:S000001374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV71-1", "uniprot_id": "ASB4_MOUSE", "id": "Q9WV71-1", "name": "Ankyrin repeat and SOCS box protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGITAPISKAGAAKLVKKDFLEALKTNDFGKLKAILIERQIDVDTV-FEVEDENMILASYKQGYWLPSYKLKSS---------WATGLHLSVLLGHVECLMVLLDHNATINCR--PNGKTPLHVACEI-----ANLECVKILCDRGAKLNCYSLSGHTALHFCTTPSS-ILCAKQLVLRGANVN--MKTNN--------------------------------QDEETPLHTAAHFGLSELVAFYVENGAIVDSMN--AHMETPLAIATYWALR--------------------------------FKEQEYSREHHLICR--------TLLDNNAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVR-------------------------------------------------------------------------------------------------------------------------------------PAAQP---EICYQLLLNHGAARIYPPQFHKVIQACHSC------------------------------PKAIEVVVN------------------------------------------------AYEHIRWNIKWRRAIPDDDLEKHWDFYHSLFKVCCNTPRTLMHLSRCAIRKALHNRCHKAIPMLSLPLPLKKYLLLEPEG--------------------------IIY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y574-1", "uniprot_id": "ASB4_HUMAN", "id": "Q9Y574-1", "name": "Ankyrin repeat and SOCS box protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGTTAPVTKSGAAKLVKRNFLEALKSNDFGKLKAILIQRQIDVDTV-FEVEDENMVLASYKQGYWLPSYKLKSS---------WATGLHLSVLFGHVECLLVLLDHNATINCR--PNGKTPLHVACEM-----ANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSS-ILCAKQLVWRGANVN--MKTNN--------------------------------QDEETPLHTAAHFGLSELVAFYVEHGAIVDSVN--AHMETPLAIAAYWALR--------------------------------FKEQEYSTEHHLVCR--------MLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVR-------------------------------------------------------------------------------------------------------------------------------------PAAQP---EICYQLLLNHGAARIYPPQFHKVIQACHSC------------------------------PKAIEVVVN------------------------------------------------AYEHIRWNTKWRRAIPDDDLEKYWDFYHSLFTVCCNSPRTLMHLSRCAIRRTLHNRCHRAIPLLSLPLSLKKYLLLEPEG--------------------------IIY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9MRX4-1", "uniprot_id": "M9MRX4_DROME", "id": "M9MRX4-1", "name": "", "aln": "---------------------------MVTENG----AQGDGNTSFLRAA----------RAGNLERVLEHLKN--NIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYS-AKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKT-KNGLAPLHMAAQG-----EHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGH-VRVAKLLLDRNADAN--ARALNGFTPLHIACKKNRLKVVELLLRHGA-SISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPT--VRGETPLHLAARANQTDIIRILLRNG------------------AQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIK----------------------------VAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGAS------------PHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPLHLSSQEGH---AEISNLLIEHKAAVNHPAKN-GLTPMHLCAQEDNVNVAEILEKNGAN---IDMATKAGYTPLHVASHFG------------------------------------------------QANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESFMSDSEEEGGEDNMLSDQPYRYLTVDEMKS-LGDDSLPIDVTRDERMDSNRMTQSAEYASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIANGSGHDEPPHVGRKLSWKSFLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGN----TPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQ-FKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAKGEPPQQPICILNIVLPEAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNTDSIARQAQSMIRLYKDKPNYDILSLETALKNIGRDDIMKKCKSGRLSHSREFDEADLMKNSESVEELVRRESKRIQQINEREEVKYSAEEKEVEESESDEEAAKRTVAERREKIVKRLS--IERSIPASTQKKEITREITEIKRKSLIEDKKAHHESEILMQLPADNVIIKTTTVPDQVIKMKMGKMDSTEVSKSEFDKELTHKFKTSGRSSEEEDQPSYPDQTDKIVQDISAAEKKEKDGVTFSRVTTITRQEARDITEDFLEIEKRSQLPATSTTATVHEKFVEEIKEKTSPLASVPQETVKEVQQVISEVTEIASKKVENIISSFESSKSVDATTVLPTQPSVESTKVSETIKNLEDAKAVSAEQVKTVHVVESSSIEETIAEFEAKKVKYDFHGGEPKTQIPKFTRKPSDDSMKPTAAPRATVESETESVLETKAEKPISKIPVKTIPTEAQKVSEVDARKITQDFLQGEKLAAEPKPSPAASKIPKVEPRKSVDKQVDRESKILDDVVASTATIMTAGLGDEQLKDQLVDHSEIIAKSETVAEKVTELLDTFHKIEEKVTKSEKTSEISSKVEELVKIEEKPLSQVQPKEDKVAEKVAEVIETFHKIEEKITTADARELTRDFLSMEQQNQLPSMPQAAEKPLESSLTSTSASEPESIVTVKPSPPASKIPVVEPRKIVFDESTKPLIEPEPVKTTEKKPLNERQLTADFLSMEQQTQLVSEPAKSLVEEVMKSAEQMVEQPKQQKSLNERQLTEDFLLMEQQTQLPSDIVKPTDKLIDGIESAAPVGDEASPFHTPKLTTSVVTQEPQQLASEYDSDTFGKQATIPLGDSKIDQGLIAPVSMEPRKSLTDAEFCKSVGETITKKMSVGVIEISDELKKIESEIPHSQTPPPTPSDNKTDKQNEEPELISLERDYLADTVTTLHTTTESTLERVSAITKIEHFSVHNVKSETFTRTDEPDKLLHSVVAPPDIQKLYSQDTTSFTEMSTSSQTPKMTTTTTMTAQIDRTKVDLTIPGQDQQKQKDLKEQSAVVVDAKAETEKTASDREYLEQIMGCGDVRRKIMRLESSCSTESLESVGKSSTVTPKYIGDNVPVVREVVQSMEDKICSTVVSAIPFTVQKRKPHDDDKEPNIVELEKQILTPADLALEKIFKCEPPSEVVKISPIEAMSLGLKEIDEEVCEKVCEKRKSFVVAEDLCETEKTLTEQVIDLNRQVDQVPARVFTETIERHLDLEDRDVIEALPKVREVVQDIERKYPAASLEAKPFSPRKRVTPDRKVDVSSLEQQILTDADLILDGLGSKCVPEQKVQSPIFSSNKASSSTENLEDICEKKCSKRTISDMTKVFERQEDPTTMPSIKDVKSTTAKFLESESGKFAITESIQHFNAKGSINKEVAGIEKGQIRFLKDCDTQEFPIETNLDTKLVEFPKITHTLERLHSISKTDIADTKKVVHESSEFKSKLDKLVHKTEQTDNQNPDKFKFPTQDNFDELQTQKSLTSELVTMTDSSEYKFPPEGKSILGKEPIESESDEELDNLNKICKLQLLSKIEQSSFIDTTEIANTEKREITKFPTTNDSHSDLFSKSRATLKTQSGEKTHCTHFTETISDKNYNSFSDTSFLLNSVTASADKSPLHPEEKTKSPEKKDEKVLAQPDDNFKSVIETDKPSPKEYSDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPVKIDEEVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSLTTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKILAKPDDSSKSVVKTDKPSPKEYSDDEIEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHREEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTYGGDGSPLHPEEKPKSPEKKDEKVLAKSDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSLTTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPVKIEEEVLAKPDDSSKSVVETDKLSPKEYSDDETEDEIEIPKPLDKPFKEAMPSVTPVSTIPDVRAIDVVSFKAEECSTTIQTNIKLASTSITTKDTKIVKPIDSLSNLKDDKFPTSVGDKAQSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKILAKPDDSSKWVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPVKTEEKVLAKPDDISKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLNPEEKPNSPEKKDEKVLAKPDDISKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISQPTSLVTGATFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLNPEEKPNSPEKKDEKVLAKPDDISKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPICQPTSLVTGATFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDKIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSITTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETDDEIDIPKALDKPISHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDENDDEIDFPKALDKPISHTTSLVTSVTGGGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSGDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDSPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDGEIDFPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDGEIDFPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHQTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTSVTGSGDKSPSLVTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKQDDRSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDRSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLQPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPFSHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFDVDKSPLHPEEKPKSPDKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKTKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKTKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVIFGGDKSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEISKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDFPKPLDKPMSHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKRSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKRSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDNSSKSFTETDKPSPKEHSDGGRKGTGLSSICLKKITPFMTEEITTSIQTNFKSASSIRATLDTQISNPTSEPGQKTLSVTPLIDDQGISQHPGEKLKTISPIAQKFETQQSYLDHHVGVDLVSDIKENRSVQQIVEDTIRAGDAEVQKIVDETLKSVQKTRDIKEQVVDEGRSVEQIVEDTLKNAKYIPNISKEDKLYCPQLKETDAQEVRPVAYFVNLDDEKKSLDPVKKVPVRSQTKKIIKSETGKILDGASAKPMNKSTISKRTLTVREKPKPKPVSPAKTTIVKQTPSRKTINTDKSKLSNKTESRRSVTSSTSTTTSSASATSRVISEIHFERSSSPASSSIFYESQPQGEGSRSTTPRPRVKTDVTRIPYNTSPRSFSPQLKTTKTDKKTVNQTKTTATRSIKELTEKSSKKTERFASQEHVEKRKTPTPSATHRYMQPTLAHSMRYGLSGDGDIGQNVTLTSPKSPAPPKSPTPALTKSTRRTQTITSALTKSTSQITKQKNSIAEMKQAQPRSQIKRGSQSDSKESLIKSTDRLYKRQTSKENKLANVIGSKSQATKSMKTQSANSAKKLVSKTSIETDNKLLKKTTATIQRTKVPISVSSSARTAAKLSKSDDTVKRPQVDNKKPVKRTVSKVSESSGTTTTTTTSTRIVAKSMEPKLQKKMKDTMNESSSNSGSGTTSASGSSNSTRRSVRSVSTVSRKTDKDLTNIRRASGAVVSTSTVRVHREPTATTSAVSTVLVDDDCEVITIRSIKSSDSTKSSTSSSSGSGSNSRKVLTSEVFTKTFGPDKPLEVVYRQPEFDVEHHTIMSVRPPSATSSDQQRCINEFDVSFIDTTDSSLSDSVALPMLGSGDPDRLLAASPGSPKPTRSPLALIEETLRRQQQHHHHQQHHHHSSGAIAAALDPSLSMPVAFGESHLEAEVEVEKGSISKETLHERKVELSNLDTEKISHEIGDVKVGGGDDDSDGDSGDFVARIREEANILVDRVLEESVEIIESQGHQANGHEIAKLDYNSESENYAITCDDIGGVDVIKSPTIESMSGKSFDDNMSFTDEHIHLPLHAQNTSTTMTTTITTQFQQQQSQSAVSSTSAAKDPVAVLESVPVSFPVASSRNQTEDESETRARRIDHKIEKLSTDMDDVSARFDEAFEMSVPEDEISALQGDFSKLSWDESVSPTTNTMADMAQNQITPDNDIQDLIAETGGDLPNSSETDTTPVPPSKESESKTETEPTVVTNAFTTTSHDTPTPKPRVLKASSPVSEGTDSTTIPGPVPKPEIPIDISFDANAPVPKPRAPIKHTEPFENLAALAEQSDSISLRSFELTEDISKTDEPSTELSIRSQLRDIVTTTTVSEDHTESFEPTSEISVDDADTEKSEGAEKTTSFYIGESSRNVIIKTSTRSASVTPQEEEAQGEIGIDAKDISLMKEVSVDSDEANDVFKEFITMKPEDPIAMDSKITRQGSETRNDILEFENADKDKTAEQKLSKVTTEESLTTSTGSSGRAIIEIAPSSSEDPDESSKEIPEIVNTISEKAAASDNFELPLEKSEWETSEKEIPTEGKPKVVHSPQQPQEASMKSTLDRFHVDEILAEEQVTDEHSSSDHKSFKDQTPSELGSSTVPQEYTFAVESEDISSFIGIPEASMQTSTLDSTQPPEGLFDTTIKETLNKQAAMAHYAQDVFGRGERRDDHGSLGFISTGTAEELSSMEEHMAKEEQASLGFISTETAEDFSSMEDYYSEKLAIASVVADEVATEKSLTTSTFEELSSDQSMKPIDVVVHRLKTETSPDSINRWSIPDVDTSSSSESFHRSFDKTQSRPLSSDLDNLVTTTGTGTSSDYQTAREFTTTGRTEGTEYISAVSTLGSSSLDSQSETSANLASIDVSELSETLVASSAEVDAFEAEEMSRLRDLRADDEDSDESVELPGTAGYPSIEQQSLMKRSQEMIFKPKTLDDEPLAVQVAQIEEYPKPKEAERTWGLAYPLEDSKVDSPRESEKGEDILLYHGDPRRSIDESKLASSLDEGSILSVSMSSTSNIDTVVENFDDIIGSAGSSSLTGIEGFQYGHDESIPSASVPEDATFMLEMESKEHSPQDSNASTPPGGESKRRGHKRNESISGDALKNLDKEVALLGEGKESESESDTDPYESEYARQFRSPKERKSKKKKQAAAEMDHSGELEKRPFTPSQLVAEVIVEDSITEELEAEAAMIEERRPSQNMQDYSNIPDIMVTEDIKSPILEEETDEFPEKMLYKVRTEEELHKASDTSVYQKAKAEEKEQDFQRRVQEQYRQKLEELKRAEVGAEYDDRKAPDSPDSFEMVEQPDISDEFVIIEEVAKEANEVDLGGQSIKIKPVKYEQKHDEDVEKIIIKSAPADPKLGSQLYKDDLNFEFEESPPTGASSSSEQQEESDSSETAAANKRWVEMQLTDNQLRYPYDLAGAVLEDIKEEDGEFEVGSSRISSFKDSFSSTPEYDVAARRYHSRGEHDDVSMSSLQEFESLEQAISLENRNRTHQGSTDSSNGSFTRRYVVRHSGSGTAPGDDVSVSSLKDFEGLENACIEAHLIEIKAREEAALLSRSDESNKSNGSDKGATGNVVVTKVTRTVTRTEVVPSSQVESIEALLKQKLEREEGSVQGRVTDIGTTELDTKSKIDSQDSEKDSIDSMEISKSHDMMTSSIESFDISKDATTRSDVDSLEIDKRHSRQESIESFGDEQLDLMTKFVSGGGVTLGDGLTTTTTTTTTSTDADGHEHTVTRVITTITNVGGGIQELPMDESGMSKDVSVDSLNMCVEQTTSSAGTTATYQTSAGNSQMSGSVTSCASSTLMEDSFPGVGGMSSSQMSASFWSHDESTVVEDEGRDLAKKPQQGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KIE7-1", "uniprot_id": "Q0KIE7_DROME", "id": "Q0KIE7-1", "name": "", "aln": "----MTLGDVRVENKIQTRSETCAINGMALDNKNGIIKQNDATISFLRAA----------RSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYV-AKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKT-KNGLSALHMAAQG-----EHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGH-VKVAKLLLDYKANPN--ARALNGFTPLHIACKKNRIKMVELLIKHGA-NIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPT--IRGETPLHLAARANQADIIRILLRS-------------------AKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN----------------------------VVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSS------------PNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSG-FSPLHLAAQGGN---VDMVQLLLEYG-VISAAAKN-GLTPLHVAAQEGHVLVSQILLEHGAN---ISERTRNGYTPLHMAAHYG------------------------------------------------HLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLKIVTSTSVINSNIGAIEEKLKVMTPELMQETLLSDSDDES-CDDLLDHNHYKYMATDDLKANYGQDQKNFDTTN-----------TDHDLTDVSVLNKKEILPNEMSCIELTEIGHKPDNVVIAR-----SQVHLG-------FLVSFLVDARGGSMRGYRHNGVRIIVPPKACAEPTRITCRYVKPQRVVNPPPLMEGEALVSRILEMSPVDGMFLSPITLEVPHYGTLRKNEREIIILRSDNGESWREHNLYK--DIIG---------EDINQTEEFHSDRIVRIVTQNVPHFFAVVSRVRQEVHVIGPDGGTVFSTAVPQVKAIFPPHALTKKIRVGLQAQSVDLVECSKLLGQGVAVSPVVTVEPRRRKFHKAITLSIPAPKACTNSMVNACYGNGNSSSPTLRLLCSISGGQTRATWEDVTGSTPLSFVRDSVTFTTTVSARFWLIDCRNIIDAGRMATELYSHLAKVPFYVKFVIFAKRISQTEAKFSVFCMTDDKEDKTLEQQEYFKEVAKSRDIEVLQNQIVYLEFAGNIVPILKKGEQLYTK-FQPFCENRLSFSAHIKDQEFPHG-RICFMTYPMVGPDEVPLKPLCTLNISVDFKTITN----------HLERDNLHSLNDCINAH-----------------------------------------------------------------------------------GKLNHN------------------------------------------------------ENIVFGVKEQQVKKID--ITKACIMSSDIKLIH--------------------------------------------------------------------------------------EADVILDDICSHLG--SDWPLLANVLGVSQADIDLVKTEFLLN-----------------------------------DSVKQSMAMLQLWLEHGGILTGNVL-------------------------------------AEALYKIGRSDIVEKS-----------------FKNAEFGTHQPE-----------------------------------------------------------------------------------KVLPTAGIEKDGDYEQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BTI7-1", "uniprot_id": "ANR52_MOUSE", "id": "Q8BTI7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "-------------------------------------------------------------------------------MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSA-----------------------------DVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVC-DKKERQPLHWAAFLGHLEVLKLLVARGADLSCKDRKGYGLLHTAAASGQIEVVKHLLRMGAEIDEPN-AFGNTALHIACYL-----GQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN--YQSKEGKSPLHMAAIHGRFTRSQILIQNGS-EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRG--IHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFN----------CLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKG-RTALFLATERGS---TECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNG------------------------------------------------HVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALS--------TDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTP-----------------------------------------------------------------------------------LHCAVINNQDSTTEMLLG-----------ALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQ--------------AEVNATDHTGRTALMTAAESGQTA---------------------------------------------AVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQALLSR-------------------------------------------------------GATVLAVDEEGHTPALACAPNKDVADCLALILSTMKP---FPPKDAVSPFSFSLLKNCGIAAAKTVGGCGALPHGASCPYSQER---------HGA-IGLDGCYSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NB46-1", "uniprot_id": "ANR52_HUMAN", "id": "Q8NB46-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "-------------------------------------------------------------------------------MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSA-----------------------------DVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVC-DKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPN-AFGNTALHIACYL-----GQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN--YQSKEGKSPLHMAAIHGRFTRSQILIQNGS-EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRG--IHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFN----------CLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKG-RTALFLATERGS---TECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNG------------------------------------------------HVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALS--------TDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTP-----------------------------------------------------------------------------------LHCAVINNQDSTTEMLLG-----------ALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQ--------------AEVNATDHTGRTALMTAAENGQTA---------------------------------------------AVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQALLSH-------------------------------------------------------GATVLAVDEEGHTPALACAPNKDVADCLALILSTMKP---FPPKDAVSPFSFSLLKNCSIAAAKTVGGCGALPHGASCPYSQER---------PGA-IGLDGCYSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502K3-1", "uniprot_id": "ANR52_DANRE", "id": "Q502K3-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "-------------------------------------------------------------------------------MGVLNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGA-----------------------------DVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSAS-DKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPN-AFGNTALHVACYT-----GQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVN--MQSKEGKSPLHMAAIHGRFTRSQILIQNGG-EIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQG--IHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQNQED------GEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFN----------TLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVG-RSVLYLASQRGH---SRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGG------------------------------------------------HTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADH--------SQPQDPLTDRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPFTP-----------------------------------------------------------------------------------LHCALINGHSGSAELLLES----------SVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQG--------------ADIDAVDHSGRSALMVAADYGQSG---------------------------------------------AVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIHNPILINATNSMLQMPLHIAARNGLATVVQALLNR-------------------------------------------------------GATVLAVDEEGHTPALACASNKAVADCLALILSTMKPSSSTASSSSPSSPSLNLLKHCGITAACPPLPNGGLRHG----YGKDR---------HGATIGLDGCLTE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B2RXR6-1", "uniprot_id": "ANR44_MOUSE", "id": "B2RXR6-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B", "aln": "-------------------------------------------------------------------------------MAVLKLCEQPPLVQAIFSGDPEEIRMLIHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSA-----------------------------DVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAF-DKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEIN-VYGNTALHIACYN-----GQDAVVNELIDYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVN--IQSKDGKSPLHMTAVHGRFTRSQTLIQNGG-EIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCG--IHSMFPLHLAALNAHSDCCRKLLSSG------------------FEIDTPDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERT-------NTG---FEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKG-RTALYLAAFKGH---TECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNPEVVDVKDAKGQTPLMLAVAYG------------------------------------------------HIDAVSLLLEKEANVDAVDIVGCTALHRGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELLQIALS--------EED-CCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTP-----------------------------------------------------------------------------------LHCAIINGHESCASLLLG-----------AIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHD--------------AQVNAVDNSGKTALMMAAENGQAG---------------------------------------------AVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAK-------------------------------------------------------GACVLAVDEN------ASRSNG--------------PRS--PPG--------TAVRKEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8A2-1", "uniprot_id": "ANR44_HUMAN", "id": "Q8N8A2-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B", "aln": "-------------------------------------------------------------------------------MAVLKLTDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSA-----------------------------DVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAF-DKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEIN-VYGNTALHIACYN-----GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVN--IQSKDGKSPLHMTAVHGRFTRSQTLIQNGG-EIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCG--IHSMFPLHLAALNAHSDCCRKLLSSG------------------FEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERT-------NSG---FEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKG-RTALDLAAFKGH---TECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYG------------------------------------------------HIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALS--------EED-CCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTP-----------------------------------------------------------------------------------LHCAIINDHGNCASLLLG-----------AIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHS--------------APVNAVDNSGKTALMMAAENGQAG---------------------------------------------AVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEKNNALQTPLHVAARNGLKVVVEELLAK-------------------------------------------------------GACVLAVDEN------ASRSNG--------------PRS--TPG--------TAVQKEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q505D1-1", "uniprot_id": "ANR28_MOUSE", "id": "Q505D1-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "aln": "-------------------------------------------------------------------------------MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSA-----------------------------DVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAF-DKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPN-AYGNTPLHVACYN-----GQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN--MKSKDGKTPLHMTALHGRFSRSQTIIQSGA-VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRG--IHGMFPLHLAALSGFSDCCRKLLSSG------------------FDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG---------------------------KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSG-RTPLDLAAFKGH---VECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNG------------------------------------------------HTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATS--------VDANPAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSP-----------------------------------------------------------------------------------LHCAVINDNEGAAEMLID-----------SLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQN--------------AQVNSADSTGKTPLMMAAENGQTN---------------------------------------------TVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGK-------------------------------------------------------GASVLAVDENGYTPALACAPNKDVADCLALILATMMPVS--SSS-PLTSLTFNAINRYTNTSKTVSFEALPIMRNEASSYCSFNNIGGEQEYLYTDVDELNDSDSETY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15084-3", "uniprot_id": "ANR28_HUMAN", "id": "O15084-3", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "aln": "-------------------------------------------------------------------------------MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSA-----------------------------DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAF-DKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPN-AYGNTPLHVACYN-----GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN--MKSKDGKTPLHMTALHGRFSRSQTIIQSGA-VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRG--IHGMFPLHLAALSGFSDCCRKLLSSG------------------FDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG---------------------------KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSG-RTPLDLAAFKGH---VECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNG------------------------------------------------HTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAAS--------MDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSP-----------------------------------------------------------------------------------LHCAVINDNEGAAEMLID-----------TLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHN--------------AQVNSVDSTGKTPLMMAAENGQTN---------------------------------------------TVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGK-------------------------------------------------------GASVLAVDENGYTPALACAPNKDVADCLALILATMMPVS--SSS-PLSSLTFNAINRYTNTSKTVSFEALPIMRNEPSSYCSFNNIGGEQEYLYTDVDELNDSDSETY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBZ2-1", "uniprot_id": "E9QBZ2_DANRE", "id": "E9QBZ2-1", "name": "", "aln": "-------------------------------------------------------------------------------MVVLKIRDQPALLKAIFNVDPDEVRSLIFKKEDVNVQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSA-----------------------------DVNARDKNWQTPLHVAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGANINAF-DKKDRRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHAAASSGMISVVKYLLDMGVDMNEPN-AYGNTPLHVACYN-----GQDVVVNELIECGANVNQVNEKGFAPLHFTAASRHGALCLELLVGNGADVN--IKSKDGKTPLHMTAIHGRFSRSQAIIQNGA-EIDCEDKNGNTPLHIAARYGHELLINTLITNGADTAKRG--VHGMFPLHLAALSGFSDCCRKLLSSG------------------FDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELDKRGCTPLHYAAASDADG---------------------------KCLEYLLRNDANPGIRDNQGYNAVHYASAYGHRLCLELIASETPLDVLMETSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQG-HTPLDLAAFKGH---VECVDVLINQGASILVKDYTLKRTPIHAAATNGHSECLRLLIGNADLQSAVDIQDGIGQTPLMLSVLGG------------------------------------------------HTDCVYSLINKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASACGHVGVLGGLLHAAQS--------VESIPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTEGNPFSP-----------------------------------------------------------------------------------LHCAVINDNEGAVELLIE-----------TLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHN--------------AQVNCVDAGGKTPLMMAAENGQTN---------------------------------------------AVEVLVSSAKADLTLQDANKNTALHLACSKGHETSALLILEKITDRNLINSTNAALQTPLHVAARNGLTVVVQELLAK-------------------------------------------------------GASVLAVDENGYTPALACAPNKDVADCLALILATMMPVS--PGGGSVPTLTFSAINHYTSPTKSVTFDSLPMLRSEHSSYCSFNSIG-RHDGFYKD-EELNDSDSETY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IWZ3-1", "uniprot_id": "ANKH1_HUMAN", "id": "Q8IWZ3-1", "name": "Ankyrin repeat and KH domain-containing protein 1", "aln": "MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTVRLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGGGASGSDEDEVSEVESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTR----------MKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN-ENGHTPLMEAASA-----GHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE--HKTDEMHTALMEACMDGHVEVARLLLDSGA-QVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVN--DEGYTPLMEAAREGHEEMVALLLAQG-----------------ANINAQTEETQETALTLACCGGFSEVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTD----------------------------VADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGAN-----------VNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDG-STMLIEAAKGGH---TNVVSYLLDYPNNVLSVPTTDVSQLPPPSQDQSQVPRVPTHTLAMVVPPQEPDRTSQENSPALLGVQKGTSKQKSSSLQVADQDLLPSFHPYQPLECIVEETEGKLNELGQRISAIEKAQLKSLELIQGEPLNKDKIEELKKNREEQVQKKKKILKELQKVERQLQMKTQQQFTKEYLETKGQKDTVSLHQQCSHRGVFPEGEGDGSLPEDHFSELPQVDTILFKDNDVDDEQQSPPSAEQIDFVPVQPLSSPQCNFSSDLGSNGTN-----------------SLELQKVSGNQQIVGQPQIAITGHDQGLLVQEPDGLMVATPAQTLTDTLDDLIAAVSTRVPTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVG---------------------------------------------VVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGAN---KEHRNVSDYTPLSLAASGGYVNIIKILLNAG-------------------------------------------AEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPSDIECMRYIATITDKELLKKCHQCVETIVKAKDQQAAEANKNASILLKELDLEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQEEDEENKPKENSELPEDEDEEENDEDVEQEVPIEPPSATTTTTIGISATSATFTNVFGKKRANVVTTPSTNRKNKKNKTKETPPTAHL--ILPEQHMSLAQQKADKNKINGEPRGGGAGGNSDSDNLDSTDCNSESSSGGKSQELNFVMDVNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPLSSPNIKLNLTSPKRGQKREEGWKEVVRRSKK-----------------LSVPASVVSRIMGRGGCNITAIQDVTGAHIDVDKQKDKNGERMITIRGGTESTRYAVQLINALIQDPAKELEDLIPKNHIRTPASTKSIHANFSSGVGTTAASSKNAFPLGAPTLVTSQATTLSTFQPANKLNKNVPTNVRSSFPVSLPLAYPHPHFALLAAQTMQQIRHPRLPMAQFGGTFSPSPNTWGPFPVRPVNPGNTNSSPKHNNTSRLPNQNGTVLPSESAGLATASCPITVSSVVAASQQLCVTN---------TRTPSSVRKQLFACVPKTSPPATVISSVTSTCSSLPSVSSAPITSGQAPTTFLPASTSQAQLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANSCSSSASNTPGAPETHPSSSPTPTSSNTQEEAQPSSVSDLSPMSMPFASNSEPAPLTLTSPRMVAADNQDTSNLPQLAVPAPRVSHRMQPRGSFYSMVPNATIHQDPQSIFVTNPVTLTPPQGPPAAVQLSSAVNIMNGSQMHINPANKSLPPTFGPATLFNHFSSLFDSSQVPANQGWGDGPLSSRVATDASFTVQSAFLGNSVLGHLENMHPDNSKAPGFRPPSQRVSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTRVFLQGPAPVGTPSFNRQHFSPHPWTSASNSSTSAPPTLGQPKGVSASQDRKIPPPIGTERLARIRQGGSVAQAPAGTSFVAPVGHSGIWSFGVNAVSEGLSGWSQSVMGNHPMHQQLSDPSTFSQHQPMERDDSGMVAPSNIFHQPMASGFVDFSKGLPISMYGGTIIPSHPQLADVPGGPLFNGLHNPDPAWNPMIKVIQNSTECTDAQQIWPGTWAPHIGNMHLKYVN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0T2-1", "uniprot_id": "ANKS6_RAT", "id": "P0C0T2-1", "name": "Ankyrin repeat and SAM domain-containing protein 6", "aln": "------------------------------------------------------------------------------MGEGALAPGLQLLLRACEQGDTDTARRLLEPGGEPVAGSEAG------AEPAGPEAARAVEAGTPVPVDCSDEAGNSALQLAAAGGHEPLVRFLLRRGAS-----------------------------VNSRNHYGWSALMQAARCGHASVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGATVDHRNPSGESTASGGSR--------------------DELLGITALMAAVQHGHEAVVRLLMEWGADPNHTARTVGWSPLMLAALL-----GKLSVVQQLVEKGANPDHLGVLEKTAFEVALDRKHRDLADYLDPLTTVRPK--TDEEKRRPDIFHALKMGNFQLVKEIADEDPNHVNLVNGDGATPLMLAAVTGQLPLVQLLVEKHADMNKQDS-VHGWTALMQATYHGNKEIVKYLLNQG------------------ADVTLRAKNGYTAFDLVMLLNDPDTELVRLLASVCMQVNKDRGGRPSHRPPLPHSKARQPWSIPMLPDDKGGLKSWWSRMSNRFRKLKLMQTLPRG-------------------LAANQPLPFSDEPELALDSTMRAPPQDRTNHLGPPEAAHAAKDSGPG---------------NPRREKDDVLLTTMLRNGAPFPRLPSDKLKAVIPPFLP-PSSFELWSSDRS---RTCPNGKADPMKTVLP-PRASRAHPVGCVGTDGAAGRPVKFPSISRSPTSPASSGNFNHSPHSSGGASG-------------------------------------------------VGSMSRLGGELHNRSGGSVDSVLSQIAAQRKKAAGLCEQKPPCQQSSPVGPATGSSPPELPASLLGSGSGSSNVTSSSK---------------KLDPGKRPPSGTSATSKSTSPTLTPSPSPKGHTAESSVSS---------------------------------------------------------------------------------------------------------------------SSSHRQSKSSGGSSSGTITDEDELTGILKKLS---------------------LEKYQPIFEEQE-------------------------------------------------VDMEAFLTLTDGDLQELGIKTDGSRQQILAAISELNAGKGRERQILQETIHNFHSSFESSASNTRAPGNSPCMAGWVRP--------------------------------------------------------EETVSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40480-1", "uniprot_id": "HOS4_YEAST", "id": "P40480-1", "name": "Protein HOS4", "aln": "---------------------------------------------------------------MNETTTKQPLKKRSLSSYLSNVSTRREELEKISKQETSEEEDTAGKHEQRETLSEEVSDKFPENVASFRSQTTSVHQATQNNLNAKESEDLAHKNDASSHEGEVNGDSRPDDVPETN-----------------------EKISQAIRAKISSSSSSPNVRNVDIQNHQPFSRDQLRAMLKEPKRKTVDDFIEEEGLGAVEEEDLSDEVLEKNT-TEPENVEKDIEYSDSDKDTDDVGSDDPTAPNSPIKLGRRKLVRGDQLDATTSSMFNNESDSELSDID-DSKNIALSSSLFR-----GGSSPVKETNNNLSNMNSSPAQNPKRGSVSRSNDSNKSSHIAVSKRPKQKKGIYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNG---------------ADPTIRNAKGLTAFESVDDESEFDDEEDQKILREIKKRLSIAAKKWTNRAGIHNDKSKNGNNAHTIDQPPFDNTTKAKNEKAADSPSMASNID-----------------------------EKAPEEEFYWTDVTSRAGKEKLFKASKEGHLPYVGTYVENGGK------------------IDLRSFFESVKCGHEDITSIFLAFGFPVNQTSRDNKTSALMVAVGRGH---LGTVKLLLEAGADPTKRDKKGRTALYYAKNSIMGITNSEEIQLIENAINNYLKKHSEDNNDDDDDDDNN--------------------------------------------------NETYKHEKKREKTQSPILASRRSATPRIEDEEDDTRMLNLADDDFNNDRDVKESTTSDSRKRLDDNENVGTQYSLDWK--------KRKTNALQDEEKLKSISPLSMEPHSPKKAKSVEISKIHEETAAEREAR--------------------------------------------------------------------------------------LKEEEEYRKKRLEK---------------KRKKEQELLQKLAEDEKKRIEEQEKQKVLEMER-----------LEKATLEKARKMEREKEMEEISYRRAVR--------------------------------------------DLYPLGLKIINFNDKLDYKRFLPLYYFVDEKNDKFVLDLQVMILLKDIDLLSKDNQPTSEKIPVDPSHLTPLWNMLKFIFLYG------------------------------------------------GSYDDKKNNMENKRYVVNFDGVDLDTKIGYELLEYKKFVSLPMAWIKWDNVVIENHAKRKEIEGNMIQISINEFARWRNDKLNKAQQPTRKQRSLKIPRELPVKFQHRMSISSVLQQTSKEPFW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "F1RCL8-1", "uniprot_id": "F1RCL8_DANRE", "id": "F1RCL8-1", "name": "", "aln": "-MVDASTTCRMNPLSALGIDRTSLMRESLRVHGGMVYPPGIQTLQSEKGYVGDRIPNLLYKPDVSLDSRKTANSFVGLYKSSPPGIQKPLIVPGAGADTLGLDRRVVPGDKPPELSLNGGSSYLRVPSWMSPYHETGMYPFLDSSKYAALNMYKASILSQPPPYLPQHLAYQSLCAGAGG-------------------------SVAGTERLFYMPTYPPAPISSPLAPPLRIPPATVAPTTLSPMMHHQDKTVQSIGPRIHHEPSAFGQQTIHQHTQPHHQSPIDRQHSSSGNSSSNSKSIRTSSSKNLSSTSSIVSSSAGISSCTSSIVSVDSCPSLVMQPPRPTPRPPQPPAAPPPPLMDSTMEFQKPLYRSPSSSSSSSPSVSHPVYISSASQELRSPIRSSGQKPKAKEATMESTRGMGNERKGSSSPVKTSSDKSPQQGPITKDPADKPLDLSAKIMEFEGHTNGYPSKLEALAKLGYSPAARYGLPPNRELLKETLSPSSSAVSTSKTP----------ERPEIISTLPSSWVVPSPTQTISSEASQNKGSSIIKNKNLENVVPQSRSSSCPKVDDQNNGSVSSSAPIIITSTSRPSSVSPSPKMNGDWAKSVPTPPEKTPINNHSG--------------SHSSATKPSKTAKKTETPDIGFKPQQSHLENGHTPSHLYMQQGETYLSPG--------LAYSSRYLSYPVPESLSLSHLQLSGKGPVYPHPVLLGANSLYSTRLPPKPGIPFGIPPNHAEYLTYHDSQEMVHPLMSPHLPLDHKVTERLDLRPRTLDKTWHHDEPPYKRQSITDIDPDYKSEKESER---------------------------------------------QEVLGSKSLSKPHTVNKDEIVCIDLVQDDTDGSPEPDKHSTIDAKCKEPAKPVGSGTGMGNESGSNSEGKEPELMQILRSGQPAVSWPTDSEQRAEVCSPPRPHKQSDSPLHSQSEESSSEHSPLPDMLEEQTLR----------------------------------------------------------------------------------CARTSGERARADGAEFRVDRHHTNRQYVDLGKDGLEDTESHEDEEEGHGCSKGKRSSLAKRIANSSGYVGDRFKCVTTELYADSSKLSREQRALQMEGLSQEDSN-------------------------------------------LSQPAAFWERAMMRFSELELKEKEGCVSSAAPGLGREQERERELAESQHGAGDWERSQPSSRPSAALSALSDSTEQRNGTTP---------------------------------------------------ACANNRVPVLQRCGLPADVLQPHRTEEKRARDVKGEEEGSVGTATGRKRALGLEHSQGHPDCTHTTEERDGERPTRGEEDNGIASKRARLISDVWPQPSEQEVKKLKVRIELTGLRLSKPRHLHNLQELWDRQGQLNHDRPQFGATNLGLPPTSKASIPPLQTTRREKLDPCTPEVPRVAHGVPAVDRKVKTNGIEEKGLKRKAEVERGWTKEQLEYAESNTAIPALSDSFCSDSIRKFSSAVPPHHLSDKRQRLKEHRKSVGSSSPSPDPDCTFPGRLRRHGDPEKPKGKRQCKTKHLSQQERRMLLQSTNQECPELSPAHQHKVVKCSAQKRPALLSNYESSPIKPHPPSPAYQPAASPTPPCAVADVPVPPLAPAPPVSAEPPVNRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKVCDVNHRDNAGYCALHEACSRGWLSIVQHLLEHGADINCSAQDGTRPLHDAVENDHLDVVRLLLSYGADPTLATYSGRGLLKMTHSDIMECFLSDYFADLQGRVDDDPSVYWEFYGSAVCEPADDSSGYDILANPPGPGEDEDEQRDVFEFEFSDRPLLPCYNIQVSLSQGPRNWLLLSDVLKRLKMSARTFRATFTHIEVVTIAEAEFYKQASLSQLFSCPEELEGFMPDSKELLDLVEISGELVALLGSSIECLDDRWEPASRPRS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : : . : . * : * . : . . ", "identical_positions": 2, "similar_positions": 15, "identity": "0.01%" }, { "cls_id": "homologset.agr.SGD:S000001375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAQ8-1", "uniprot_id": "D3ZAQ8_RAT", "id": "D3ZAQ8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MTT-ASCILPSQA----IQQDN---------IYGLSQITTSLFISNSAVANDKLTLSNNHITTIINASVEVVN-TFFEDIQ-----YVHVPVSDAPNS------YLYDFFDPIADHIHGVE-MRNGRTLLHCAAGVSRSAALCLAYLMKYHTMTLLDAHTWTKSCRPIIRPNNGFWEQLIHYEFKLFSRNTVHMIYSP--MGLIPNIYEKDAYLMELM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9D8-1", "uniprot_id": "DUS21_MOUSE", "id": "Q9D9D8-1", "name": "Dual specificity phosphatase 21", "aln": "---------------------------------------------------------------------------------------------------MTT-ASCIFPSQA----TQQDN---------IYGLSQITASLFISNSAVANDKLTLSNNHITTIINVSAEVVN-TFFEDIQ-----YVQVPVSDAPNS------YLYDFFDPIADHIHGVE-MRNGRTLLHCAAGVSRSATLCLAYLMKYHNMTLLDAHTWTKTCRPIIRPNNGFWEQLIHYEFKLFSRNTVRMIYSP--IGLIPNIYEKEAYLMELM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H596-1", "uniprot_id": "DUS21_HUMAN", "id": "Q9H596-1", "name": "Dual specificity protein phosphatase 21", "aln": "---------------------------------------------------------------------------------------------------MTASASSFSSSQG----VQQPS---------IYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN-VFFEGIQ-----YIKVPVTDARDS------RLYDFFDPIADLIHTID-MRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSP--VGNIPDIYEKDLRMMISM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VE01-1", "uniprot_id": "DUS18_MOUSE", "id": "Q8VE01-1", "name": "Dual specificity protein phosphatase 18", "aln": "---------------------------------------------------------------------------------------------------MTS-PWSAFPVQ-----IPQPS---------IRGLSQITKSLFISNGVAANNKLLLSSNQITTVINVSVEVAN-TFYEDIQ-----YVQVPVVDAPVA------RLSNFFDSVADRIHSVE-MQKGRTLLHCAAGVSRSAALCLAYLMKYHAMSLVDAHTWTKSCRPIIRPNSGFWEQLIHYELQLFGKNTMQMMDSP--MGRIPDIYEKETRLMIPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXW7-1", "uniprot_id": "DUS18_RAT", "id": "Q6AXW7-1", "name": "Dual specificity protein phosphatase 18", "aln": "---------------------------------------------------------------------------------------------------MTS-PWSACPVQ-----FPQPS---------ISGLSQITKSLFISNGAAANDKLLLSSNQITTVINVSVEVAN-TFYEDIQ-----YVQVPVVDAPIA------RLSDFFDPIADHIHSVE-MKQGRTLLHCAAGVSRSAALCLAYLMKYHVMSLLDAHAWTKSRRPIIRPNSGFWEQLIHYEFQLFGKNTMQMVNSP--MGLIPDIYEKETRMMIPLSTPDGAFHKGKEKALL--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NEJ0-1", "uniprot_id": "DUS18_HUMAN", "id": "Q8NEJ0-1", "name": "Dual specificity protein phosphatase 18", "aln": "---------------------------------------------------------------------------------------------------MTA-PSCAFPVQ-----FRQPS---------VSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVN-TLYEDIQ-----YMQVPVADSPNS------RLCDFFDPIADHIHSVE-MKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSP--VGMIPDIYEKEVRLMIPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1EC97-1", "uniprot_id": "A1EC97_RAT", "id": "A1EC97-1", "name": "", "aln": "-----------------------------------------------------------------------------MSSRG-----------------HSTLPRTLMAP----RMISEGD---------IGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPN-FNWPQFE-----YVKVPLADIPHA------PIRLYFDTVADKIHSVS-KKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTP--YGIIPDVYEKESRHLMPYWGI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LD64-1", "uniprot_id": "A0ABK0LD64_RAT", "id": "A0ABK0LD64-1", "name": "", "aln": "-----------------------------------------------------------------------------MSSRG-----------------HSTLPRTLMAP----RMISEGD---------IGGIAQITSSLFLVRASVASNRHLLQARGITCVVNATIEIPN-FNWPQFE-----YVKVPLADIPHA------PIRLYFDTVADKIHSVS-KKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTP--YGIIPDVYEKESRHLMPYWGI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLY7-1", "uniprot_id": "DUS14_MOUSE", "id": "Q9JLY7-1", "name": "Dual specificity protein phosphatase 14", "aln": "-----------------------------------------------------------------------------MSSRG-----------------HSTLPRTLMAP----RMISEGD---------IGGIAQITSSLFLGRASVASNWHLLQARGITCVINATIEIPN-FNWPQFE-----YVKVPLADIPHA------PIRLYFDTVADKIHSVS-KKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTP--YGIIPDVYEKESRHLMPYWGI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95147-1", "uniprot_id": "DUS14_HUMAN", "id": "O95147-1", "name": "Dual specificity protein phosphatase 14", "aln": "-----------------------------------------------------------------------------MSSRG-----------------HSTLPRTLMAP----RMISEGD---------IGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPN-FNWPQFE-----YVKVPLADMPHA------PIGLYFDTVADKIHSVS-RKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTP--YGIVPDVYEKESRHLMPYWGI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T8A1-1", "uniprot_id": "A0AB32T8A1_DANRE", "id": "A0AB32T8A1-1", "name": "", "aln": "-----------------------------------------------------------------------------MGSRSQGFFHHQDHHHQHHNHHHHHHHRSSVVPTTIPRLLPEATSL-------LGGIAQITPSLFLGRGNVASNRSLLLSKGITCVVNATIELPN-FNWPHME-----YVKVPLADMPHS------PISLYFDSVADKIHSVG-RKRGAVLVHCAAGVSRSASLCLAYLMKYHRVSLAEAHAWVKARRPVIRPNGGFWRQLIEYERKLFGRNSVKMIQTP--YGVIPDVYERDRRNLAPYWGL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAB0-1", "uniprot_id": "Q9VAB0_DROME", "id": "Q9VAB0-1", "name": "Protein-tyrosine-phosphatase", "aln": "-----------------------------------------------------------------------------MQELIVGGIAISGVPFANETVEKESRQNQLSAS------TLEDHTP-------FPGLSRITPSLILCG-AAAVVPAYMDKLGVSCVINVAPELPD-TPLPSQKNP--LYLRIMAQDRSEV------DLAKHFDEAADLIEEVH-LSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRGSSSVAMVYFASLDKEIPDILEPEYRAMEDFYQRYRSSLKRR-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58HA54-1", "uniprot_id": "A0AC58HA54_DANRE", "id": "A0AC58HA54-1", "name": "", "aln": "---------------------------------------------------MFSLRSRRFPPGTLVSPTVQRHAVQVGPTLASPGQASRKRFIKRQASDMNAGRGISAHWSRAQKSRSHRGTS-------VMSISQITPTLFLSGADASMNQALMTRKGITLIVNVTLSHTC-PVYPGVE-----CIRVAVSDLPNA------RLGDHFDHVSARIHNN---RPGGTLVHCAAGMSRSPAVIMAYLMKYKGVTLRQAHKWVKDSRPYIRLNVGFWTQLLDYERKLYGRNTVRVAEPVDAQPTPQTPKLPSRYKMRQCPPSPRASQLRRFTSFSS-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4G0W2-1", "uniprot_id": "DUS28_HUMAN", "id": "Q4G0W2-1", "name": "Dual specificity phosphatase 28", "aln": "------------------------------------------------------------------------------------------------MGPAEAGRRGAASPVP-------------------PPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPG-PRAPGVA-----ELRVPVFDDPAE------DLLAHLEPTCAAMEAAV-RAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPA--LGLGPEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BV47-1", "uniprot_id": "DUS26_HUMAN", "id": "Q9BV47-1", "name": "Dual specificity protein phosphatase 26", "aln": "-----------------------------------------------------------------MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTA-------CNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWR-GTPEAYEGLGIRYLGVEAHDSPAF------DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIP-NRGFLRQLLALDRRLRQGLEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHV8-1", "uniprot_id": "Q9VHV8_DROME", "id": "Q9VHV8-1", "name": "protein-tyrosine-phosphatase", "aln": "MCVNRETQSSSNNNSNNTTTATSTARNNNSHNGRCECDGDGDSVSHIQSEMKMRIKREAPCLLLFMPIQNTNNNNRIGANQKDYPNKRSRENLACDEVTSTTSSSTAMNGGGRTPALTRSCSSPAVYDIETHPASPVFPHLLLGNGRDADDP---SSVGANCVLNVTCQSPNESHLQGLK-----YMQIPASDTPHQ------NIKQYFQEAYDFIEDAR-KTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPHLNSPSNPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVDSGSGSLAGSNCSSRLTSPPITPDDEAPSTSAAASSVSELDSPSSTSSSSGICSLLQSTSSSVSPRAISKPNLLSPTRQLALFKRNSPAKLRLDLESSYAPASPIPNTMPWLSVPSTPVCEEAPDSRINHVASNLTRD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40479-1", "uniprot_id": "SDP1_YEAST", "id": "P40479-1", "name": "Dual-specificity protein phosphatase SDP1", "aln": "------------------------------------------------------------------------MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLD-------VRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEAN-----DLR------MQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAAT-TKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTNVQANSYR----KVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : . : : : : : :. *::* * ***.:: **:* . : * .: : . .: ** : * ", "identical_positions": 14, "similar_positions": 25, "identity": "2.85%" }, { "cls_id": "homologset.agr.SGD:S000001376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P81155-1", "uniprot_id": "VDAC2_RAT", "id": "P81155-1", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "------------------------------------------------------------------MAECCVPVCQRPICIPPPYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFS--PNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFG----------IAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60930-1", "uniprot_id": "VDAC2_MOUSE", "id": "Q60930-1", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "------------------------------------------------------------------MAECCVPVCPRPMCIPPPYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFS--PNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFG----------IAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45880-3", "uniprot_id": "VDAC2_HUMAN", "id": "P45880-3", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "------------------------------------------------------------------MATHG-QTCARPMCIPPSYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFS--PNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFG----------IAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60932-1", "uniprot_id": "VDAC1_MOUSE", "id": "Q60932-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "-----------------------------------------------------------------MCSFFLVLLLWQNMAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFS--PNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2L0-1", "uniprot_id": "VDAC1_RAT", "id": "Q9Z2L0-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "------------------------------------------------------------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFS--PNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21796-1", "uniprot_id": "VDAC1_HUMAN", "id": "P21796-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "------------------------------------------------------------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFS--PNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60931-1", "uniprot_id": "VDAC3_MOUSE", "id": "Q60931-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFV--PNTGKKSGKLKASYRRDCFSLGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNERIETSINLAWTAGSNNTRFG----------IAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFNAGGHKVGLGFELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y277-1", "uniprot_id": "VDAC3_HUMAN", "id": "Q9Y277-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFV--PNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFG----------IAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1Z0-1", "uniprot_id": "VDAC3_RAT", "id": "Q9R1Z0-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCSTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLIFTQKWNTDNTLGTEISWENKLAEGLKLTVDTIFV--PNTGKKSGKLKASYRRDCFSVGSKVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLCQNNFALGYKAEDFQLHTHVNDGTEFGGSIYQRVNEKIETSINLAWTAGSNNTRFG----------IAAKYRLDCRTSLSAKVNNASLIGLGYTQSLRPGVKLTLSALVDGKNFNAGGHKVGLGFELEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BEA1-1", "uniprot_id": "A0A8M2BEA1_DANRE", "id": "A0A8M2BEA1-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "-----------------------------------------------------MSEKGHKQKGSSETCHHCKPKTCANMAVPPAYADLGKSAKDIFSKGYGFG-TVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFV--PNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSNNTRFG----------IAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94920-1", "uniprot_id": "VDAC_DROME", "id": "Q94920-1", "name": "Voltage-dependent anion-selective channel", "aln": "-------------------------------------------------------------------------------MAPPSYSDLGKQARDIFSKGYNFG-LWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFA--PQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFA----------IGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP2-1", "uniprot_id": "Q9VKP2_DROME", "id": "Q9VKP2-1", "name": "", "aln": "-----------------------------------------------------------------------------MAAKTPTYPDLGKLARDLFKRGYHPG-IWQIDCKTLTNSGIEFFTTGFASQDNSKVTGSLQSKYKIEDQGLTLTERWNTENWLFGEIMHRDKLAQGLMLAVEAKFQ--PGSNEADGKFKMGYAQDNFNFLADIGLNSE-PILNCSLVVGHKEFLGGVGTEFDVGNTELKGWKVALGWTNETATLHGELKNGDTWLASLFYKASEKIDAGIEVTKGAGGGEAAEGEQQGGDVVVNLGMIYHLEEDALVRAKVNNLVELGLGYEQKLRDGITASISAVLDCNNFKDGNHRFGVGIALQC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP4-1", "uniprot_id": "Q9VKP4_DROME", "id": "Q9VKP4-1", "name": "Voltage-dependent anion-selective channel", "aln": "MTNMKQRLRNLFRRNKMRARPTTVASDANKEQPEPPKQEPSKQKKTKQDASKQEPPKQEEPEKPPKEVEVEIIPSPTSEGEMPTYFHVGALAKDCLINGFKIG-AWQMHCSTRTDNDFYLNTFGEGYPTMKNVFGGMEVFKEVGNYSTSLG--WFTNNDLLSEIAVRGMNFGSRLYGLLKSTIGTKDEVSFQTKLKCGLERDPVKVELVVPLYNEPLFLGYVLVAPVENWVLGYRTEYNFDEKGFDKHALCLGYNNGRTEVGLKLENFEDLRGSIFQRIGEAWAFAIKTNLYSSENVKQFA----------IGVQYDFQNGTMVKAKLREDSRMGFVYQSKIGENIDVGYHLAFDGVDPIGGAHRIGVSWGFHC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP3-1", "uniprot_id": "Q9VKP3_DROME", "id": "Q9VKP3-1", "name": "Voltage-dependent anion-selective channel", "aln": "MP-MRERIRNLFRRNKRKR----AASDYLEPHDE--------GGGNVQDNRSAEEDKEEN--------KVEMLPPPPMEGEMPSYFHVGLLAKMCLIHGYTIG-RWKLQCTSKTEKDFYLSSFGEGYPTWNTVYGGLEAYKESGNFHASLA--WLSDGDLLSDLGVHGDGLGGTWSTVLKSMVSYPEGRKFQCKLKCGFDRNPGKVEMYIPIYKEPLLMGYIMMQPVKNYLLGYRTVFNVEDRDFNMHAFCGGYSNDVTEVGLKFENFKALRGSIFQRIGEKWAVALKANLYGNVSAKSVS----------IGGQYEWEPGSMLKAKVRGDSRIGLIFQKKLREDIEVLFHVGFEGSDPINGKHKFGSSWYFNM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40478-1", "uniprot_id": "VDAC2_YEAST", "id": "P40478-1", "name": "Non-selective voltage-gated ion channel 2", "aln": "-------------------------------------------------------------------------------MALRFFNDISRDVNGLFNRDFFHTNPLSLNISTTTENGVNFTLKAKQGVTEGPIQTSVEGRFYDRKEGVSLSQSWSNQNRLNTRIEFS-KIAPGWKGDVNAFLT---PQSIKNAKFNLSYAQKSFAARTSIDILQPKDFVG-SVTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCATASFFQNVNRYLQVGTKATLQSKTSSNMNIE---------FVTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDISLGVGMSFNALQLTEPVHKFGWSLSFSP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. .. : ..: .:. .: : ... : . :: . : * .:. * : . . . *:: . :. : : : . :: * :: .. *: . :: .*:: . . : . . : * : : . **: . : .: .: .: . *:.* . : ", "identical_positions": 11, "similar_positions": 77, "identity": "2.94%" }, { "cls_id": "homologset.agr.SGD:S000001380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BYP3-1", "uniprot_id": "RHOF_MOUSE", "id": "Q8BYP3-1", "name": "Rho-related GTP-binding protein RhoF", "aln": "MDAPGAPAPAAAPSSARKELKIVIVGDGGCGKTSLLMVYCQGSFPEHYAPSVFEKYTASVTVGNKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPTVLIGCKTDLRKDKEQLRKLRAAQLEP---------------------ITYTQGLNACEQMRGALYLECSAKFREN-VEDVFREAAKVALSALK-KAQRQ-------------------------KKHR-ICLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRB3-1", "uniprot_id": "D3ZRB3_RAT", "id": "D3ZRB3-1", "name": "", "aln": "MDAPGAPAPAAAPSSARKELKIVIVGDGGCGKTSLLMVYCQGSFPEHYAPSVFEKYTASVTVGNKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEP---------------------ITYTQGLSACEQMRGALYLECSAKFREN-VEDVFREATKVALSALK-KAQRQ-------------------------KKQR-ICLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBH0-1", "uniprot_id": "RHOF_HUMAN", "id": "Q9HBH0-1", "name": "Rho-related GTP-binding protein RhoF", "aln": "MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEP---------------------ITYMQGLSACEQIRAALYLECSAKFREN-VEDVFREAAKVALSALK-KAQRQ-------------------------KKRR-LCLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97348-1", "uniprot_id": "RHOD_MOUSE", "id": "P97348-1", "name": "Rho-related GTP-binding protein RhoD", "aln": "MNASQVAGEEAPQSG--HSVKVVLVGDGGCGKTSLMMVFAKGAFPESYSPTVFERYNATLQMKGKPVHLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNNLRKKRLEP---------------------VTYHRGHDMARSVGAVAYLECSARLHDN-VEAVFQEAAEVALSSRRHNFWRR-------------------------ITQN-CCLAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADM8-1", "uniprot_id": "D4ADM8_RAT", "id": "D4ADM8-1", "name": "", "aln": "MNASQTEGEEAPHSG--RPIKVVLVGDGGCGKTSLMMVFANGAFPESYNPTVFERYNATLQMKGKPVRLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNTLRKKRLEP---------------------VTYHRGHDMARSVGAVAYLECSARLHDN-VEAVFQEAAEVALSSRSHNFWRR-------------------------ITQN-FCVVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00212-1", "uniprot_id": "RHOD_HUMAN", "id": "O00212-1", "name": "Rho-related GTP-binding protein RhoD", "aln": "MTAAQAAGEEAPPGV--RSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEP---------------------VTYHRGQEMARSVGAVAYLECSARLHDN-VHAVFQEAAEVALSSRGRNFWRR-------------------------ITQG-FCVVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00245-1", "uniprot_id": "RHO3_YEAST", "id": "Q00245-1", "name": "GTP-binding protein RHO3", "aln": "MSFLCG---SASTSNKPIERKIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKG-VNEAFTEAARVALTAGPVATEVK-------------------------SDSGSSCTIM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P52198-1", "uniprot_id": "RND2_HUMAN", "id": "P52198-1", "name": "Rho-related GTP-binding protein RhoN", "aln": "MEGQSG------------RCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIP---------------------VTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:*::**. ****:*: *: . :* * *:***.* . : : : * ::**:*.. :*.:*.* * :: :::*:.: : :.: :* * ..* :::. * *:*.: . : : ::: .* ...: . *:***:: . *. .* *: .:* * ", "identical_positions": 43, "similar_positions": 67, "identity": "16.54%" }, { "cls_id": "homologset.agr.SGD:S000001382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14728-1", "uniprot_id": "S75A1_HUMAN", "id": "Q14728-1", "name": "Solute carrier family 75 member 1", "aln": "-----------------MGWGGGGGCTPRPP---IHQQPPER-RVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKG-NVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAP----WFALLFAASDLLFIFCFLPETLP----LEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDP------PSGDRLSSLRRLGLVYFLYLFLFSGLEYT--------LSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKR----------------------------------------------ALLLLVPAFLLIGWGRSLPVLG---LGLLLYSFAAAVVVPCLSSVVAGYGS---PGQKGTVMGTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40475-1", "uniprot_id": "QDR1_YEAST", "id": "P40475-1", "name": "Quinidine resistance protein 1", "aln": "MTKQQTSVMRNASIAKEEREGSDNNNVDRSSSDAISDNDAERSNSHSEIDNESNFDMVPYSRFSHKQKMLLVVQ-CAFTGFFSTVAG--SIYYPVLTIIERKFNITEELANVTIVVYFIFQGVAPSIMGGLADTFGRRPIVLWAILAYFCACIGLACAHNYAQILALRCLQAAGISPVIAINSGIMGDVTTKVERGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLVFSTLLMPETKR----TLVGNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGLQFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCISVKTPL---AAVLCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFRCLLSAIFIAALTKMVEKMRYGGVFTFLSAITSSSSLLLFYLLKNGKQLSFDRIRANDKSAGRSVGKNSEKVST", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3W7-1", "uniprot_id": "Q9W3W7_DROME", "id": "Q9W3W7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------MIPILEKLSGFYNTYVLAVLTIGYILGELGHYLIGVTSKQTAIELDYGDHACQQNTSMFNRHELPTQCSAVMNETSCYALDFNGTGYCEWNYNGLGIDYQILAGPTFILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMIMAAGESGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGGYGIAFPVGRYITKLNFWNLGWRVCYLGAGVLTVIMAALTGTTLREPERKAIGEGDRQTSSGKPVSLWQVIKNPAMIMLMIAASIRHCGGMTFAYNADLYYNTYFPDVDLGWWLFGVTIGIGSVGVVVGGIVSDKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLWAMITLGLSYFFAEMWFG---------------------IVFAIVVEIVPLRVRSSTIGVFLFVMNNIGGNLPILVDPVAKILGYRGSIMIFYAGFYGISSILFFITCFLLEGKPDEVGQPESPKSHPDAVLNARHMHGHDNSVFSVDETLPSNGRPAQLPQHLQMSSNGYDKSQISPPRQNGAESSRL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : . : :* .: . . : . . : .: :: :. : * :* .* :: . : : . :.: :: * : . . . .: :.*:.*: . *. :.:. * :. :* :. . : :. :: : * . .* : . . : . : *: :: : : .: . * . :. : : : * . .: :* :. : . : .. . . : . . * * .: . . ", "identical_positions": 19, "similar_positions": 105, "identity": "3.32%" }, { "cls_id": "homologset.agr.SGD:S000001383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14728-1", "uniprot_id": "S75A1_HUMAN", "id": "Q14728-1", "name": "Solute carrier family 75 member 1", "aln": "----MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLES---HGRAHDPLYGSWQGGVDWFATAIGMP--VEKRYN--SVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISK-GNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLG----ASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARR-IHPGGEVAAVKRALLLLVPAFLLIGWG-------RSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLG----ALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQK-----------LSYPAQTLKAE------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3W7-1", "uniprot_id": "Q9W3W7_DROME", "id": "Q9W3W7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MIPILEKLSGFYNTYVLAVLTIGYILGELGHYLIGVTSKQTAIELDYGDHACQQNTSMFNRHELPTQCSAVMNETSCYALDFNGTGYCEWNYNGLGIDYQILAGPTFILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMIMAAGESGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGGYGIAFPVGR-YITKLNFWNLGWRVCYLGAGVLTVIMAALTGTTLREPERKAIGEGDRQTSSGKP----VSLWQVIKNPAMIMLMIAASIRHCGGMTFAYNADLYYNTYFPDVDLGWWLFGVTIGIGSVGVVVGGIVSDKIVAKMG--IRSRAFVLAVS-QLIATLPAFGSVYFDPL-----WAMITLGLSYFFAEMWFGIVFAIVVEIVPLRVRSSTIGVFLFVMNNIGGNLPILVDPVAKILGYRGSIMIFYAGFYGISSILFFITCFLLEGKPDEVGQPESPKSHPDAVLNARHMHGHDNSVFSVDETLPSNGRPAQLPQHLQMSSNGYDKSQISPPRQNGAESSRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40474-1", "uniprot_id": "QDR2_YEAST", "id": "P40474-1", "name": "Quinidine resistance protein 2", "aln": "MAGATSSIIRENDFEDELAESMQSYNRETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAIYYPVLSVIERKFD-IDEELVNVTVVVYFVFQGLAPTFMGGFADSLGRRPVVLVAIVIYFGACIGLACAQTYAQIIVLRCLQAAGISPVIAINSGIMGDVTTRAERGGYVGYVAGFQVLGSAFGALIGAGLSSRWGWRAIFWFLAIGSGICFLASFLILPETKRNISGNGSVTPKSYLNRAPILVLPTVRKSLHLDNPDYETLELPTQLNLLAPFKILKAYEICILMLVAGLQFAMYTTHLTALSTALSKQYHLTVAKVGLCYLPSGICTLCSIVIAGRYLNWNYRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYTFNIFKARLQPAFVTLLLSSSGFCAYGWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDLFPTKTS-TATGCLNLFRCILSAVFIAALSKMVEKMKFGGVFTFLGALTSSSSILLFILLRKGKELAFKRKKQELGVN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : : . * * .:: . : .: :: :. : * :* .* :: :. : : . : : :: * : . . .: :.*:.*: . *. :. . * :. :* : * .. : : *. * :: : . :.:. . . : : .. : : :: . * . : . * . : . . : . .:. .. .: . . . : * ::: * : . .: * ", "identical_positions": 19, "similar_positions": 102, "identity": "3.47%" }, { "cls_id": "homologset.agr.SGD:S000001386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8H9-1", "uniprot_id": "G5E8H9_MOUSE", "id": "G5E8H9-1", "name": "", "aln": "--------------------------------------------------------MWLYLVSLVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDR---RGMRVLAACLTEK----GAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVG--NRGLWGLVNNAGISVPLGLSQWMNKQNFASVLDVNLLGMIEVTLTMLP-LVRKARGRVVNVSSIMGRVSLHGNGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPG--FFLTGMASSARLSSNTQMLWDQTSSEIREIYGEKYLAFYLKSLNELDK-RCNKDLSLVTDCMEHALTACHPRT--RYSAGWDAKLFFIPLSYLPTFLVDAVFYWTSMKPE--KAL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54909-1", "uniprot_id": "RDH16_MOUSE", "id": "O54909-1", "name": "Retinol dehydrogenase 16", "aln": "--------------------------------------------------------MWLYLVALVGLWTLLRFFRVRQVVSHLQDKYVFITGCDSGFGTLLARQLDR---RGMRVLAACLTEK----GAEELRNKTSDRLETVILDVTKTESIVTATQWVKEHVG--NRGLWGLVNNAGISTPSGPNEWMKKQDFAHVLDVNLLGMIEVTLSMLP-LVRKARGRVVNVSSVMGRVSLFG-GGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPG--FFLTGVTSSARLCSNTQMLWDQTSSEIREIYGEKYLASYLKRLNKLDK-RCNKDLSGVTDCMEHALTACHPRT--RYSAGWDAKLFYLPLSYLPTFLVDALLYWTSLKPE--KAL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGV4-1", "uniprot_id": "Q8CGV4_MOUSE", "id": "Q8CGV4-1", "name": "", "aln": "--------------------------------------------------------MWLYLVALVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDR---RGMRVLAACLTEK----GAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVG--NRGLWGLVNNAGISTPSGPNEWMKKQDFARVLDVNLLGMIEVTLSMLP-LVRKARGRVVNVSSVMGRMSFFG-GGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPG--GFKTCVTSSDRLSSNTKMIWDKASSEVKEIYGEKFLLFYLKNLNELDK-RCNKDLSVVTDCMEHALTACHPRT--RYSAGWDAKFLFLPLSYLPTFLVDALLYWTSMKPE--KAL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88451-1", "uniprot_id": "RDH7_MOUSE", "id": "O88451-1", "name": "Retinol dehydrogenase 7", "aln": "--------------------------------------------------------MWLYLVALVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDR---RGMRVLAACLTEK----GAEQLRNKTSDRLETVILDVTKTESIVAATQWVKERVG--NRGLWGLVNNAGICV-FAINEWLKKEDFANILDVNLLGMIEVTLSMLP-LVRKARGRVVNISSSMGRVSLCG-GGYCISKYGVEAFSDSLRREISYFGVKVAIIEPG--GFRTNVSNYERLSHSIEKLWDQTSSEVKEVYDKNFLDSYIKAIQSLTD-TCSDDLSVVTDCMEHALTACHPRT--RYSAGWDAKLFYLPLSYMPTFLVDAMLYWSSVKPA--QAL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R092-1", "uniprot_id": "H17B6_MOUSE", "id": "Q9R092-1", "name": "17-beta-hydroxysteroid dehydrogenase type 6", "aln": "--------------------------------------------------------MWFYLVTLVGLYHLLRWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDR---RGMRVLAACLTEK----GAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVG--DRGLWGLVNNAGVLQPFAYIEWYRPEDYMPIFQVNLIGLTQVTISMLF-LVKKARGRIVNVSSALGRVALFG-GFYSCSKYGVEAFSDVLRHEVQDFGVKVSIIEPG--SFKTEMTDAELTIERTKKVWEAAPEHIKESYGQQFFDDFCSTTKRELM-KCSRNLSLVTDCMEHALTSTHPRT--RYSAGWDAKFFFIPLSYLPASLVDYLLAISRGKPA--QAA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58NB6-1", "uniprot_id": "DHRS9_MOUSE", "id": "Q58NB6-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "--------------------------------------------------------MLFWLLALLFLCAFLWNYKGQLKIADIADKYVFITGCDTGFGNLAARTFDK---KGFRVIAACLTES----GSAALKAKTSERLHTVLLDVTDPENVKKTAQWVKSHVG--EKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLP-LVKKARGRVINVSSIGGRLAFGG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPG--LFKTELADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHRLKSNTS-SVNLDLSLVVGCMDHALTSLFPKT--RYIAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPKAV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3P0-1", "uniprot_id": "DR9C7_MOUSE", "id": "Q8K3P0-1", "name": "Short-chain dehydrogenase/reductase family 9C member 7", "aln": "------------------------------------------------------------MAALTDFAFMYRWFKNCNLVKNLSEKYVFITGCDSGFGNLLAKQLVD---RGMKVLAACLTEE----GAQKLLQDTSHQLQTFLLDVTKSENVKEAAQWVRDQVG--EQGLWALVNNAGVGLPSGPNEWLTIKDFVKVININLVGLIDVTLNMLP-MIKKARGRVVNMSSSGGRVAIFG-GGYCVSKFGVEAFSDSIRRELHFFGVKVSIIEPG--NYKTSILGQEALESRMKKLWDRLPQETRDSYGEEYFQTYTKKLVNLMR-SAEPRISDVTNSMEHAIVSRSPRI--RYNPGLDVKFLYLTLAKLPTPVTDFILSRYLPRPA--DSV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55240-1", "uniprot_id": "RDH5_MOUSE", "id": "O55240-1", "name": "Retinol dehydrogenase 5", "aln": "---------------------------------------------------------MWLPLLLGALLWAVLWLLRDRQSLPASDAFIFITGCDSGFGRLLALQLDQ---KGFQVLAGCLTPS----GAEDLQQMASSRLHTTLLDITDPQNVQQVAKWVKTRVG--ETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLP-LLQQARGRVVNITSVLGRIAANG-GGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPG--FFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMNLICDPELTKVTSCLEHALTARHPRT--RYSPGWDAKLLWLPASYLPARVVDAVLTWILPRPA--QSVS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80XN0-1", "uniprot_id": "BDH_MOUSE", "id": "Q80XN0-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "------------------------------MLAARLSRPLSQLPGKALSVRDRENGTRHTLLFYPASFSPDTRRTYASQADAASGKAILITGCDSGFGFSLAKHLHS---KGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGIST-FGEVEFTSMETYKEVAEVNLWGTVRTTKSFLP-LLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCN-SGSTDTSSVINAVTHALTAATPYT--RYHP---MDYYWWLRMQIMTHFPGAISDKIYIH-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51658-1", "uniprot_id": "DHB2_MOUSE", "id": "P51658-1", "name": "Estradiol 17-beta-dehydrogenase 2", "aln": "MS--PFASESAWLCLAAAAVLGGTLLCGCRSGRQLRSQAVCLAGLWGGACLLSLSLLCTLFLLSVACFLLLYMSSSDQDLLPVDQKAVLVTGADSGFGHGLAKHLDK---LGFTVFAGVLDKE--GPGAEELRKHCSERLSVLQMDVTKPEQIKDAHSKVTEKIQ--DKGLWAVVNNAGVFHLPIDGELIPMSIYRKCMAVNFFGTVEVTKAFLP-LLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAALTMFSTIIRQELDKWGVKVVTIKPGG-FKTNITGSQDIWDKMEKEILDHFSKDIQENYGQDYVHTQKLIIPTLKE-RSNPDITPVLRDIQHAISARNPSS--FYYPGRMAYLWVCLAAYCPTSLLDYVIKKGFYPQPTPRALRTVH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51661-1", "uniprot_id": "DHI2_MOUSE", "id": "P51661-1", "name": "11-beta-hydroxysteroid dehydrogenase type 2", "aln": "MERWPWPSGGAWLLVAARALLQ-LLRSDLRLGRPLLAALALLAALD-WLCQRLLPPPAALVVLAGAGWIALSRLAR-PPRLPVATRAVLITGCDTGFGKETAKKLDA---MGFTVLATVLDLN--SPGALELRDLCSPRLKLLQMDLTKAEDISRVLEITKAHTA--STGLWGLVNNAGLNIVVADVELSPVATFRKCMEVNFFGALELTKGLLP-LLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFGCELLPWGIKVSIIKPGC-FKTDAVTNVNLWEKRKQLLLANIPRELLQAYGEDYIEHVHGQFLNSLR-MALPDLSPVVDAIIDALLAAQPRS--RYYPGRGLGLMYFIHHYLPEGLRRCFLQNFFINHLLPRALRPGQHGPAPA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYR8-1", "uniprot_id": "RDH8_HUMAN", "id": "Q9NYR8-1", "name": "Retinol dehydrogenase 8", "aln": "--------------------------------------------------------------------------------MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQGEVD-------VLVNNAGMGL-VGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPG---PVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQ-NPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLSCGCLPTRVRPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40471-1", "uniprot_id": "AYR1_YEAST", "id": "P40471-1", "name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "aln": "----------------------------------------------------------------------------MSELQSQPKKIAVVTGASGGIGYEVTKELAR---NGYLVYACARRLEP---MAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLP--DGKLDLLYNNAGQSCTFPALDATD-AAVEQCFKVNVFGHINMCRELSE-FLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGG--VATDIADKRPLPETSIYNFPE---------GREAFNSRKTMAKDNKP---MPADAYAKQLVKDILSTSDPVD---VYRGTFANIMRFVMIFVPYWLLEKGLSKKFKLDKVNNALKSKQKNKDD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*.. *:* : : * * . : ::: . :.: : **** * * . : : :* :: * * * :* .: : :: .: : .* . : . ", "identical_positions": 17, "similar_positions": 37, "identity": "4.22%" }, { "cls_id": "homologset.agr.SGD:S000001387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI78-1", "uniprot_id": "ODO1_RAT", "id": "Q5XI78-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNKPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDILTHIGNVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPNLQEENFDISQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--EDGPAAQNPDKVKRLLFCTGKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60597-1", "uniprot_id": "ODO1_MOUSE", "id": "Q60597-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNKPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDVLFHIGKVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--ENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02218-1", "uniprot_id": "ODO1_HUMAN", "id": "Q02218-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNRPAAA-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPT---TTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMSCPSTGLTEDILTHIGNVASSVP--VENFTIHGGLSRILKTRGEMVKN-RTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP--EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTISRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFKNFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JI08-1", "uniprot_id": "B8JI08_DANRE", "id": "B8JI08-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MHRLRTCAARLRPITASQTAKNLSQQGPAATPRTFQPLRCFSSPVAAEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNANAGAPPGTAYQSPPPLG-VSLAGLAQAQSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGIMDADLDSCVPTDIITSSDKLGFYGLEESDLDKVFRLPT---TTFIGGDESALPLREIIRRLEMAYCQHIGVEFMFINDLDQCQWIRQKFERPGVMQFSLEEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVDTVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTNRNITLSLVANPSHLEAVNPVVQGKTKAEQFYSGDTDGK-RVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIKKQKGVLQKYAEKLIAEGAVTRQEYEEEIAKYDKICEEAHSRSKDEKILHIKHWLDSPWPGFFT-LDGQPKSISCPSTGLPEEELAQIGQVASSVP--VEDFTIHGGLSRILKGRGDMIKN-RTVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICIPMNHMSPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDFNPKITD-DFDVRQLYDCNWIVVNCSNPANYFHVIRRQILLPFRKPLIVFTPKSLLRHPEAKSNFDQMLPGTHFQRVIT--DDGPPAQNPSEVKRIVFCTGKIYYELTRERKARNMENSVAITRIEQLSPFPFDLVRAETEKFPN-ADLVWCQEEHKNQGYYDYVKPRMRTTINRT-------------------------------------------------------------------------------------------------KPVWYAGREPAAAPATGNKNTHLLELKRFLDTAFNLDAFKDHI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ULD0-1", "uniprot_id": "OGDHL_HUMAN", "id": "Q9ULD0-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "----MSQLRLLPSRLG----VQAARLLAAHDVPVF---GWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRP-------PSVVHESRSAVSSRTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPT---TTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAAD-EGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGK-KVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFN-VDGEPKSMTCPATGIPEDMLTHIGSVASSVP--LEDFKIHTGLSRILRGRADMTKN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTK-DFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIP--EDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPG-AELAWCQEEHKNMGYYDYISPRFMTILRRA-------------------------------------------------------------------------------------------------RPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZQD3-1", "uniprot_id": "OGDHL_RAT", "id": "D3ZQD3-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "----MSQLRLLLFRLG----PQARKLLATRDIAAF---GGRRRSSGPPTTIPRSRGGVSPSYVEEMYFAWLENPQSVHKSWDNFFQRATKEASVGPAQPQP-------PAVIQESRASVSSCTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPT---TTFIGGSENTLSLREIIRRLESTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMKFSIEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGVENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAAD-EGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGR-KVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFN-VDGEPKSMTYPTTGIPEDTLSHIGNVASSVP--LEDFKIHTGLSRILRGRADMTKK-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQDVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPVFTE-DFEVSQLYDCNWIVVNCSTPASYFHVLRRQVLLPFRKPLIVFTPKSLLRHPDAKSSFDQMVSGTSFQRMIP--EDGPAAQSPERVERLIFCTGKVYYDLVKERSSQGLEKQVAITRLEQISPFPFDLIMREAEKYSG-AELVWCQEEHKNMGYYDYISPRFMTLLGHS-------------------------------------------------------------------------------------------------RPIWYVGREPAAAPATGNKNTHLVSLRKFLDTAFNLKAFEGKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8JNU6-1", "uniprot_id": "A8JNU6_DROME", "id": "A8JNU6-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "MHRAHTAFSLALSPMAHKNFATWLLKSSSSQQMAKVTAAAAVRTYNS-AAAEPFANGSTASYVEEMYNAWLRDPTSVHTSWDAYFRSNSYVSPPNLAPVQANTLP---LTAFNFGGAVAGAAP-DSKTIDDHLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYAN-----FSFGEQDMDRQFKLPS---TTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFTQFAG-LEAAD-DGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDQEGK-KVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFFE-GKD---PLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDE-KVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPESD-EFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIP--DNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANLYKN-AELVWAQEEHKNQGSWTYVQPRFLTALNHSRDVSQSDEQSSSTNTTTTTDHTNHESDTDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAAKHFDLKNVRHDFNRPAGIAAAPGARIAKTGRKISYVGRACGASTATGSKAQHIRELNALLNDAIST--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20967-1", "uniprot_id": "ODO1_YEAST", "id": "P20967-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "------MLRFVSSQTCRYS-SRGLLKTSLLKNAST---VKIVGRGLATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGIS----FGSNKNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRP-TTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKD-YVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPESTLKELGKVLSSWP---EGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSE-AIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEK---LQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHK-RRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKET--------------------------------------------------------------------------------------------DKYKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVFQQS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . ..*::*** ** .:* *** *** :*: . . . . .: :. ** ** : *:**:*** *::*** * . . : . :.: : *:*: :.* . . * . : :.*:**: :** **. *::: .* . ::*:*:*:::* * ::: ::** :* *:. : ** ** *:..:******* * ::*.:* ::* * *:: :::**.******.*:** ** :.** :* * :****:***** .* .:.: : *::********: :*** *:*:* . .* . : :.:.:*:******.***:****: : **.*:* **:**:.***********::**:** :*:*:.::*******::* *** .: .:***** .*:.* ::*:* :*:.**** *:* *******::* :: :. *:: *:::*... : .. .: *:*. :* :.** :.* ** . : .*.: *. * .:*. ** * * :* .* *:* * . *** .* :***:*: :* ::*:**:********:** ***.* : .:. : ::* :::.*******.*:*** *::::.*: **:******** * ** ******. *: ** ::.*:*: **** :* ****** * *****:..:*. * . * * *: *. :.*.. :*::*** ***** : .*.***** *:: :.:: * ** :* :.* . ..::::: :*::* * : * *: ::**: **** : . : : . ::.*.*** * * : * .**: * : .: : * ** ..: *:*.: *: . :*. .:. ", "identical_positions": 347, "similar_positions": 298, "identity": "30.49%" }, { "cls_id": "homologset.agr.SGD:S000001388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1P7-1", "uniprot_id": "SMCA4_RAT", "id": "Q8K1P7-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMGPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGSDPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPLVPLH----QKQSRITPIQ-KPRGLDPVEILQEREYRLQARIVHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEG--TLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDEESKKQKK-----------RGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS------------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLG-RKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSDEEQEEDRSGSGSEED------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TKT4-1", "uniprot_id": "SMCA4_MOUSE", "id": "Q3TKT4-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMAPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGSDPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPLVPLH----QKQSRITPIQ-KPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEG--TLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDEESKKQKK-----------RGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS------------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLG-RKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51532-1", "uniprot_id": "SMCA4_HUMAN", "id": "P51532-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN--QMKGMGMRSGGHAGMGPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLH----QKQSRITPIQ-KPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEG--TLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKK-----------RGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSS-----------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLG-RKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PTG1-1", "uniprot_id": "E9PTG1_RAT", "id": "E9PTG1-1", "name": "", "aln": "MATPTDPA-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEGLHQLHKPMDGIHDKGIVEDVHCG--SMKGTSMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTP-PQMPPSQPGTLIPG-DLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGMQQQQQQQQQQQQQQQ---------------QQQP-----QQPQQPQQQTQAQPQQQQQQQQQPP---ALVSYNRPSGPGQELLMTAQNTQQKLSAPAPSGR--------------PSPAPPAATQPTATAVPGPSVQQPAPGQPSPVLQLQ----QKQSRISPIQ-KPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGEPALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESESDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDG--NLEEMEEEVRLKKRKRRRNVDKDP------------VKEDVEKAKKR-----------RGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------EESNEEEEEEDEEESEAE----AKSVKVKIKLN-KKEEKGRDTGKGKKRPNRG-KAKPVVSDFDSDEEQDENEQSEASGTDDE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DIC0-1", "uniprot_id": "SMCA2_MOUSE", "id": "Q6DIC0-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "aln": "MSTPTDPA-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPLSTMGSADFPQEGMHQLHKPMDGIHDKGIVEDVHCG--SMKGTSMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSS------PTP-PQMPPSQPGALIPG-DPQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGMQQQQQQQQQQQQQQQ---------------QQQQQQQQQQQPQQPQQQAQAQPQQQQQQQQQP----ALVSYNRPSGPGQELLLSGQSAPQKLSAPAPSGR--------------PSPAPQAAVQPTATAVPGPSVQQPAPGQPSPVLQLQ----QKQSRISPIQ-KPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGEPALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESESDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDG--NLEEMEEEVRLKKRKRRRNVDKDP------------VKEDVEKAKKR-----------RGRPPAEKLSPNPPKLTKQMNAIIDTVINYKD------------------SSGRQLSEVFIQLPSRKDLPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------EESNEEEEEDDEEESESE----AKSVKVKIKLN-KKEEKGRDTGKGKKRPNRG-KAKPVVSDFDSDEEQEENEQSEASGTDNE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51531-1", "uniprot_id": "SMCA2_HUMAN", "id": "P51531-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "aln": "MSTPTDPG-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCG--SMKGTGMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGLQQQQQQQQQQQQQQQ---------------QQQQ------QQQQPQQQ---PPQPQTQQQQQP----ALVNYNRPSGPGPE--LSGPSTPQKLPVPAPGGR--------------PSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQ----QKQSRISPIQ-KPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRK------PRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDG--NLEEMEEEVRLKKRKRRRNVDKDP------------AKEDVEKAKKR-----------RGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------DESNEEEEEEDEEESESE----AKSVKVKIKLN-KKDDKGRDKGKGKKRPNRG-KAKPVVSDFDSDEEQDEREQSEGSGTDDE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25439-1", "uniprot_id": "BRM_DROME", "id": "P25439-1", "name": "Brahma chromatin-remodeling complex ATPase subunit", "aln": "MASPSPANSPMPPP-----QAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAYGHPMQHGPPGQGPPGHHMPPHHQGMIFSKGPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVSPGGPPGGPPPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMRATSK-HQHLNGNQVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQPPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQVGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVA-KPVGLDPITLLQERENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSG-EYIG-----IDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWID-DEEDSCGSNDDHKPKVEEQPT----------ATEDATDKAQATGNDEDAKDLITKAKVE-DDEY------RTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTG--EKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTG-GHGVVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEE--------------------------------EEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPGR------ERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDG--AEFDEEEEEDDSKRKRRKRKNRKE------------ESDDDSLILKR-----------RRRQNLDKRS------KKQMHKIMSAVIKHNQD-------------------GRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDEEIATTSAAAVKMKLK-LNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32597-1", "uniprot_id": "STH1_YEAST", "id": "P32597-1", "name": "Nuclear protein STH1/NPS1", "aln": "MLQEQSELMSTVMN-----NTPTTVAALAAVAAASETNGKLGSEEQPEITIP---KPRSSAQLEQLLYRYRAIQNHPKENKLEIKAIEDTFRN--------------------------------------------------------------ISRDQDIYETKLDTLRKSIDKGFQYDED---LLNKHLVALQLLEKDTDVPDYFLDLPDTKN---------------------------------------------------------------------------------------------------------DNTTAIEVDYSEKKPIKI---------------SADFNAKAKSLGLESKFSNATKTALGDPDTEIRIS---ARISNRINELERLPANLGTYSLDDCLEFITKDDLSSRMDTFKIKALVELKSLKLLTKQKSIRQKLINNVASQAHHNIPYLR-DSPFTAAAQRSVQIRSKVIVPQTVRLAEELERQQLLEKRKKERNLHLQKINSIIDFIKERQSEQWSRQERCFQFGRLGASLHNQMEKDEQKRIERTAKQRLAALKSNDEEAYLKLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQQNE----------------------------------------------------AKILHGEEVQPITDEE-------------------------------------------------------------------------------------REKTDYYEVAHRIKEKIDKQPSILVGGTLKEYQLRGLEWMVSLYNNHLNGILADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAPSLNTIIYKGTPNQRHSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHDWAHMIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNFVLPKIFNSAKTFEDWFNTPFANTGTQEKLELTEEETLLIIRRLHKVLRPFLLRRLKKEVEKDLPDKVEKVIKCKLSGLQQQLYQQMLKHNALFVGAGTEG-ATKGGIKGLNNKIMQLRKICNHPFVFDEVEGVVNPSRG------NSDLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDIMEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILERAMQKLDIDGKVIQAGKFDNKSTAEEQEAFLRRLIESETNRD--------------------------------DDDKAELDDDELNDTLARSADEKILFDKIDKERMNQERADAKAQGLRVPPPRLIQLDELPKVFRED----IEEHFKKEDSEPLGR-IRQKKRVYYDDGLTEEQFLEAVEDDNMSLEDAIKKRREARERRRLRQNGTKENEIETLEN-TPEASETSLIENNSFTAAVDEETNADKETTASRSKRRSSRKKRTISIVTAEDKENTQEES-----------TSQENGGAKVEEEVKSSSVEIINGSESKKKKPKLTVKIKLNKTTVLENNDGKRAEEKPESKSPAKKTAAKKTKTKSKSLGIFPTVEKLVEEMREQLDEVDS--------------HPRTSIFEKLPSKRDYPDYFKVIEKPMAIDIILKNCKNGTYKTLEEVRQALQTMFENARFYNEEGSWVYVDADKLNEFTDEWFKEHSS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:. . . ... . * * :* . : : .. . :: . *. :: * ::* :. :. : : . * *. . . . * : .**. : * .*.. : : * : *:: :: . .*: : : :::* . . : * *:.: :* : . *:* : .* :*:**:** :* .:*.*: * : : ::::. *: :. : . : :: : . * : *::::*. ** *:*: * ::***.* **:**.** *:: ** **:.:: .*:: * :: .* * * :. . . ** :** : *:: :*.::::.*.**.**::****:******:****************:*:*:*** : *: **:*:******:.**. **:****:: : ***:* *: : *:* :*:********:**** :*:* * :**:******** :.**: .:. :* : *::********:**********:**.**:*..***:***:*** ** *:::*.****:*********************** :**:*** :***.:*.**: **::* :. *:.... :. *** * * *.*:****:****::*:.:* * .. *:*.:********:***::*:.*:**:* ***. * *:**:: : : *:****:**:*:* :*. ** .*: * ***************:****:***:*******************:****:*** *.:**** ** * **::* ****** **:**:. *:. **: ::. : : : ::. **: :* :** :* :* ::* :* .:: : **:: .***. : :* . : ::. :** *::: * * *.***:::*.*:::. : :: : *: . : .: . :. : . * .*: *: : : : * * :: .* : : . ::* ** . . .. :: *: : : .*: : .. :.: : . . :. . . :.: * :. : . .. : . . ", "identical_positions": 406, "similar_positions": 363, "identity": "23.03%" }, { "cls_id": "homologset.agr.SGD:S000001390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6T4-1", "uniprot_id": "M0R6T4_RAT", "id": "M0R6T4-1", "name": "MMS19 nucleotide excision repair protein", "aln": "MAAATALEEAAAPMGALCGLVQDFVMGQQEGPADQVAADVKSGGYTVLQVVEALGSSLENPEPRTRARGIQLLSQVLLQCHSLLL-EKEAVHLTLFYENRLKDHHLVVPSVLQGLRALSLSVALPRGLAVSVLKAIFQEVHVQ--SLLQVDRHTVFSIITNFMR------SREEELKSLGADFTFGFIQVMDGEKDPRNLLLAFRIVHDLISKDYNLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSCSVLRADAEDLLHPFLSSILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACEHITSNVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYED----------RDERPLSNFKDQLCSLVFMALTDPSTQLQLVGIRMLTVLGAQPDLLSAEDLELAVGHLYRLSLLEEDAQSCRVAALEASGSLATLYPGAFSSHLLPRLAEGLHQGESDVARADGPT----KCSRHFR--CLQALSAVSTHPDIVKETLPLLLQHLCQAHKGNMITESSEVVAVCQSLQQVAEKCQQDPESYWYFHKTAVPCLFALAVQASVPEKASSVLSKALLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPGHFQPFQ--GGSSGQRRLVALLMAFVCSLPRNVEIP-ELTRLMQELLKQSCGHSCPFSSTAASKCFAGLLNKQPPGQQLDEFLQLSVDTVEAGLASESS--RNQAFTLLLWVTKALVLRYHPLSASLTARLMGLLSDPELGCAAADGFSLLMSDCTDVLTRAGHAD---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDSVVQLSTLS-CLQPLLLEAPQIMSLHVDTLVTKFLNLS---SSHSMAVRIAALQCMHALT-RLPTSVLLPFKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D071-1", "uniprot_id": "MMS19_MOUSE", "id": "Q9D071-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "MAAATGLEEAVAPMGALCGLVQDFVMGQQEGPADQVAADVKSGGYTVLQVVEALGSSLENAEPRTRARGAQLLSQVLLQCHSLLS-EKEVVHLILFYENRLKDHHLVVPSVLQGLRALSMSVALPPGLAVSVLKAIFQEVHVQ--SLLQVDRHTVFSIITNFMR------SREEELKGLGADFTFGFIQVMDGEKDPRNLLLAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSCSVLRADAEDLLGSFLSNILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACEHLTSNVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYED----------RDERPLSSFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPGLLSAEDLELAVGHLYRLTFLEEDSQSCRVAALEASGTLATLYPGAFSRHLLPKLAEELHKGESDVARADGPT----KCSRHFR--CLQALSAVSTHPSIVKETLPLLLQHLCQANKGNMVTESSEVVAVCQSLQQVAEKCQQDPESYWYFHKTAVPCLFALAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPDQFQPFQ--DGSSGQRRLVALLTAFVCSLPRNVEIP-QLNRLMRELLKQSCGHSCPFSSTAATKCFAGLLNKQPPGQQLEEFLQLAVGTVEAGLASESS--RDQAFTLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGCAAADGFSLLMSDCTDVLTRAGHAD---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDSVVQLSTLS-CLQPLLLEAPQIMSLHVDTLVTKFLNLS---SSYSMAVRIAALQCMHALT-RLPTSVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T76-1", "uniprot_id": "MMS19_HUMAN", "id": "Q96T76-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "-MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNYTVLQVVEALGSSLENPEPRTRARAIQLLSQVLLHCHTLLL-EKEVVHLILFYENRLKDHHLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQ--SLPQVDRHTVYNIITNFMR------TREEELKSLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVTSCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSRSVLRADAEDLLDSFLSNILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACDSVTSNVLPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYED----------KDQRPLNGFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALEASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPT----QCSRHLC--CLQALSAVSTHPSIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAIPCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVPLFLDGNVSFLPENSFPSRFQPFQ--DGSSGQRRLIALLMAFVCSLPRNVEIP-QLNQLMRELLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLGSGPC--RSQAFTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHAE---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDCVVQLSTLS-CLQPLLLEAPQVMSLHVDTLVTKFLNLS---SSPSMAVRIAALQCMHALT-RLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBU4-1", "uniprot_id": "MMS19_DANRE", "id": "E7FBU4-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "---------MAADNNVLLGLVEEFVSGQVDSKAADTSTGVKNGQFTVLQLVEALGVSLTSSQPQTRGRGVQLLSQVLQECYSGLS-EREVEVLIAFYENRLKDHYVITPHVLRGLKALAKCSVLPPGSAVSILKSIFQDVHVQQQSLMVTERSCVYNILISLME------SREEELKGLGADFIFGFVQSVDGERDPRNLLLAFQVAKNIIYRGYDLGKFVEELFEVTSCYFPIDFSPPPNDPHGITQEELILSLRAVLTGTPRFAEFLLPLIIEKMDSDVQSAKVDSMHTLAACGQTYSHKELAEFLPGLWSSIRREVFQTASERV--------ESAGLSALSSLVSCLSRSVLNSDSEDSLQVFLNLVLKSDCQHHLCEPDLKLVWP-SAKLLQAAAGASYRASLIGTQAVIPALLDQYNNRTQCAQRRTLLEVLQGFVQPTPLSRPADGVSCISTHTHEEESVLVAFQQSLCTVVFSALSETSAGLQVTATRVLTALSQQPGLLSQTDVENAVDHLTRLILEEEEAQVS-LAVVECSGSLAHLHPHAFVSRMIPQLKEKILSGRVHTVMEKTLSGSLYECSGAVRRRCVAALASVSSQPSVVQESSPVLLQVLTSAHTGCCGFSVEEVIAVCISLQRIAVHARDNEAIGQFFHDIIIPRLLGLTLQAALQSKDSGHIS-PLTDEAVLSAIVPVISTACAALKPESASRMAAQAVSLFLDGDTSFLPENAFPSQIQPLQSQADSRGPSQLVCLLMACVCSLPRSVEIP-DMDRLLVQLEDLSCTSPHLFSYTFASKCIAGLVNKRPAGAALNAVLDRVLKRVSLELEETSSTHRTQAFTLLIWVAKALLLRYHPLSTALTDKLFSLLSDSALGSLVADGFCVLMNDSPDVLNRDCHAD---VRIMYRQRFFTENSSKLVQGFN-SAEQAKKSCYLKALSHIVNNLPREVQLTELPALLPLLLEALSCVDQGVQLSTLS-CLQPVLLESPAALNTQLEALFTRLLALT---TSPAMKVRMASLRCVHALS-RLPEHMVMPFRARVLKALAAPLDDKKRLVRKEAVAARGEWFLLGSPGG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95U54-1", "uniprot_id": "MMS19_DROME", "id": "Q95U54-1", "name": "MMS19 nucleotide excision repair protein", "aln": "---------MTTPTRATLEKALKSDQKLVN-SATQIAKDLTAKAYDISALAEALGFALSSPDMEERVAGTNLLSAVLIALPQDLLQERQLEFLSTFYMDRLRDHHNVMPAIIDGIDALVHMKALPRAQIPQILQSFFEHTTCQ--SQTRSDRTKLFHIFQYLTE------NFQDELQAMAGDFVYGLINSIDGERDPRNLDIIFSFMPEFLS-TYPLLHLAEEMFEIFACYFPIDFNPSKQDPAAITRDELSKKLTNCLVANNEFAEGTVVLAIEKLESELLVAKLDSIELLHQAAVKFPPSVLEPHFDQIWQALKTETFPGNDN----------EEILKASLKALSALLER---AAHIPDISHSYQSSILG-VILPHLSDVNQRLFHP-ATGIALVCVSG--DAPYAADKILNSFLLKLQAADASSEQRIKIYYIVSQVYKLSALR--------------------GSLQKLDTTIRESVQDDVIASLRLIEQEEFDAKKE-----------------------DLELQKAALSVLNESAPLLNEKQRALIYKALVQLVSHPSIDIDFTTLTVSLG-------------ALQPVEVQSNFIDVCVRNFEIFSTFVKRKIYTNLLPLMPQIAFTQRILDLVMTQTFNDTT-------AEPVRLLALEALNKLLLLADQRFIVDVQQESNLLHKLIELGQKTEGLSMQSLEQIAGALS--RITQQLPLSEQSAIVSEYLPGLN----LSQSADLYITKGLLGYLHKDITLDDHFERLLTDLTQLSLNSDNEQLRVIAHHLLCSMVNKMESNPANLRKVKKITEQLKVAIKKGDVR----AVEILAWVGKGLVVAGFDEAADVVGDLSDLLKHPSLSTAAALGFDIIAAEYP----ELDLPV---VKFLYKQKLFHT----IMGKMG-SKLANYCVHHLKAFVYVLKATPQAVIKLNIEQLGPLLFKSLEEHNEAQSLCIALGICEKFVAQQDTYFQGHLAHLIPSCLELSKYKAQHTMQVRIAALQLLYDVT-KYPTFVLLPHKVDVTLALAAALDDPKRLVRNTAVKARNAWYLVGAPSPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40469-1", "uniprot_id": "MET18_YEAST", "id": "P40469-1", "name": "DNA repair/transcription protein MET18/MMS19", "aln": "-----MTPDELNSAVVTFMANLNIDDSKANETASTVTDSIVHRSIKLLEVVVALKDYFLSENEVERKKALTCLTTILAKTPKDHLSKNECSVIFQFYQSKLDDQALAK-EVLEGFAALAPMKYVSINEIAQLLRLLLDNYQQG--QHLASTRLWPFKILRKIFDRFFVNGSSTEQVKRINDLFIETFLHVANGEKDPRNLLLSFALNKSITSSLQNVENFKEDLFDVLFCYFPITFKPPKHDPYKISNQDLKTALRSAITATPLFAEDAYSNLLDKLTASSPVVKNDTLLTLLECVRKFGGSSILENWTLLWNALKFEIMQNSEGNENTLLNPYNKDQQSDDVGQYTNYDACLKIINLMALQLYNFDKVSFEKFFTHVLDELKPNFKYEKDLKQTCQILSAIGSGNVEIFNKVISSTFPLFLINTSEVAKLKLLIMNFSFFVDSYIDLFGR----------------TSKESLGTPVPNNKMAEYKDEIIMILSMALTRSSKAEVTIRTLSVIQFTKMIKMKGFLTPEEVSLIIQYFTEEILTDNNKNIYYACLEGLKTISEIYEDLVFEISLKKLLD-----------LLPDCFEEKIRVNDEENIHIETILKIILDFTTSRHILVKESITFLATKLNRVAKIS--KSREYCFLLISTIYSLFNNNNQNENVLNEEDALALKNAIEPKLFEIITQESAIVSDNYNLTLLSNVLFFTNLKIPQAAHQEELDRYNELFISEGKIRILDTPNVLAISYAKILSALNKNCQFPQKFTVLFGTVQLLKKHAPRMTETEKLGYLELLLVLSNKFVSEKDVIGLFDWKDLSVIN-----------LEVMVWLTKGLIMQNSLESSEIAKKFIDLLSNEEIGSLVSKLFEVFVMDISSLKKFKGISWNNNVKILYKQKFFGDIFQTLVSNYKNTVDMTIKCNYLTALSLVLKHTPSQSVGPFINDLFPLLLQALDMPDPEVRVSALE-TLKDTTDKHHTLITEHVSTIVPLLLSLSLPHKYNSVSVRLIALQLLEMITTVVPLNYCLSYQDDVLSALIPVLSDKKRIIRKQCVDTRQVYYELGQIPFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * : .: : :. ** : . : * . *: :* :.: : ** .:* *: :: *: ** :. .:*: :::. . * : *: : . :::: : * ::: :**:***** : * . .: : : *::*:: ***** *.*. :** * .::* * :... *** ::*: :. .* *:: * . : . : :* ::: * : . : : : . : * : . .: .. . . : . : :. : .: : . :. .: : : : : : : . . : . . . . : : .: * : . *: : : * . . : . . : * :. : .: *: : . :: . :. . :: *: *.*:: :: :. : .**.. :. .: * :: : . . *:::::*::* :: : :*..: ::: * : * .**:::*. : :. : : : :: :.. * *: :: **: :*: : :: * :..: * ** *.* **::*: .* :* :: :* ", "identical_positions": 86, "similar_positions": 235, "identity": "7.96%" }, { "cls_id": "homologset.agr.SGD:S000001391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G1L6-1", "uniprot_id": "A0A8I6G1L6_RAT", "id": "A0A8I6G1L6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NASPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPAMLPINVDPDSKPGEYVLKSVFVSFTTQAERKIRIIMAEP--LEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGMEDES------------------------------------------------------------HEYRP----RTSNKSKSD----------------EQQR--DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDGLVHDIINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRQKEQSPYVVQSIISLIMGVKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAATVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLK---------------NKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDM-PLNIFVKIIQFIAQERLDFAMKEIIFDFLCVG-KPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--VSKVELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREEVLFGFTNFLLREVNDVHHTLLDSSLK-------LLLQLLTQWKLVIQTQGRVYEQA--------------------------------------------KIRNSELIPNGS-GHRMQSER----------------------GPHCSVLHAVEGFALVLLCSFQMATRKLSVLILKEIRALFLALGQ-PEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPPTHN-VDLQWLVEWNA----------------VLVNSHYDVKSPSHVWIFAQSVK---DPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPVNAKKTSTASSG-DNYVTLWRNYLILCFGVAKPSIMSPG--------HLRASTPEI-MATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADASVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVT-LLNLVLFKASDTNREIYEVSMQLMQILKAKLF---LHSKKAAEQRPGSVLYGTHGPLPPLYSVSLALLSRELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSS----PSSPEDEVKDREGEVTASHGLKGKGWGSPEATSLVLNNLMYMTAK----------------YGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKATAAASGTTSS---SNTVVAGQDSFPDP-------EESKILK---ESDDRFSN-VIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG--------------------------WLLSITEAKQPQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEVKTLTMQPAYQPEYLYTGGFDFLR--------------------------------EDQSSPVPDSGLSSSSTSSSISLGGSSGNLPQMTQEVEDVD-AAAESDEKA--------------NKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSKS-GLHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSS--------PDLSSSSKLTASRKSTGQLNVSPGTP--------SGSTATAERSRHQRSFSVPKKFG--VVDRSSDPPRSATLDRIQACTQQG-LSSKTRSSSS-----LKESLT-----------DPSHVNHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAQMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSRVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKGIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYCLLSYMDLSVVPGKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLP-----SYQHSDLSKIELHR--VWTSA----SKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPR-AMAVTRSASSTSSGS-NSN-VLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSED--GTREQENMDDANSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDM-QTLEE-RQLSR---STPSLNK-------MSHEDSDESSEE--DLTASQILEHSDLIMNLSPSEEAN--PMELLTSACDSTPADPHPFN--------ARITNFEASLPDINNLQISEGSKAEVVPEEEDTTVH-------------------------------------------------------------------EDDLSSSIN-ELPATFECSDSFSLDMTEAEE---------KGNRGLDQYTLASFGEGDR-------GVSPPPSPFFSAILAAFQPVSCDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLAN----CKATFAGSSRDEVITCQPGDSEEK------------QLELCQRLYKLHFQLLLLYQSYCKLIG-QVHEVSSVPELLNMSRELSDLKRKLKEATAAISTD-PLYIEGAWSEPTFT-------STEAAIQSMLECLKNNDLGKALRQIKECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIR----RAQSSRVLT-----------------TFLPDSSVSGTSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8I9-1", "uniprot_id": "FRY_MOUSE", "id": "E9Q8I9-1", "name": "Protein furry homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NASPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPAMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEP--LEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGIEDES------------------------------------------------------------HEYRP----RTSNKSKSD----------------EQQR--DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDIINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQSPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLK---------------NKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDM-PLNIFVKIIQFIAQERLDFAMKEIIFDFLCVG-KPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--MSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLK-------LLLQLLTQWKLVIQTQGRAYEQAN-------------------------------------------KIRNSELIPNGS-SHRMQSER----------------------GPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFLALGQ-PEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPPTHN-VDLQWLVEWNA----------------VLVNSHYDVKSPSHVWIFAQSVK---DPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPVNAKKTSTASSG-DNYVTLWRNYLILCFGVAKPSIMSPG--------HLRASTPEI-MATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVT-LLNLVLFKASDTNREIYEVSMQLMQILEAKLF---VHSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSS----PSSPEDEVKDREGEVTASHGLKGNGWGSPEATSLVLNNLMYMTAK----------------YGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVATYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSS---SNTVVAGQDSFPDP-------EESKILK---ESDDRFSN-VIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG--------------------------WLLSITEAKQPQPLPMPCSGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEAKTLTMQPAYQPEYLYTGGFDFLR--------------------------------EDQSSPVPDSGLNSSSTSSSISLGGSSGNLPQMTQEVEDVE-AATETDEKA--------------SKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSRS-GFHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSS--------PDLSSSSKLTASRKSTGQLNVNPGTPGSGGGGGGSGNTTTAERSRHQRSFSVPKKFG--VVDRSSDPPRSATLDRIQACTQQG-LSSKTRSNSS-----LKESLT-----------DPSHVSHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAHMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTSVSKVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYSLLSYMDLSVVPVKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLP-----SYQHSDLSKIELHR--VWTSA----SKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPR-AMAVTRSASSTSSGS-NSN-VLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSED--GPREQENMDDTNSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDM-QILEE-RQLSR---STPSLNK-------MSHEDSDESSEE--DLTASQILEHSDLIMNLSPSEEAN--PMELLTSACDSAPADPHSFN--------TRMANFEASLPDINNLQISEGSKAEAVPEEEDTTVH-------------------------------------------------------------------EDDLSSSIN-ELPAAFECSDSFSLDMTEAEE---------KGNRGLDQYTLASFGEGDR-------GVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLAN----CKATFAGGSRDGVITCQPGDSEEK------------QLELCQRLYKLHFQLLLLYQSYCKLIG-QVHEVSSVPELLNMSRELSDLKRNLKEATAAIATD-PLYIEGAWSEPTFT-------STEAAIQSMLECLKNNELGKALRQIKECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIR----RAQNYRVLT-----------------AFLPDSSVSGTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TBA9-1", "uniprot_id": "FRY_HUMAN", "id": "Q5TBA9-1", "name": "Protein furry homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NTSPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPTMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEP--LEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGIEDES------------------------------------------------------------HEYRP----RTSNKSKSD----------------EQQR--DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDVINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQNPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHIFLNNCLSNLK---------------NKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITIITTLFPKGSRGVVPRDM-PLNIFVKIIQFIAQERLDFAMKEIIFDFLCVG-KPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVDNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--MSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLK-------LLLQLLTQWKLVIQTQGKVYEQAN-------------------------------------------KIRNSELIANGS-SHRIQSER----------------------GPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFIALGQ-PEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPLTHN-VDLQWLVEWNA----------------VLVNSHYDVKSPSHVWIFAQSVK---DPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPINAKKTSTAGSG-DNYVTLWRNYLILCFGVAKPSIMSPG--------HLRASTPEI-MATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGSRNYPFDIVT-LLNLVLFKASDTNREIYEISMQLMQILEAKLF---VYSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSS----PSSPEDEVKDREGDVTASHGLRGNGWGSPEATSLVLNNLMYMTAK----------------YGDEVPGPEMENAWNALANNEKWSNNLRITLQFLISLCGVSSDTVLLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSS---SNTVVAGQENFPDA-------EENKILK---ESDERFSN-VIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG--------------------------WLLTITETKQPQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHSIASVLLQTREMGEAKTLTVQPAYQPEYLYTGGFDFLR--------------------------------EDQSSPVPDSGLSSSSTSSSISLGGSSGNLPQMTQEVEDVD-TAAETDEKA--------------NKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLTNFLRHVVSVFKDSKS-GFHLEHQLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLLTVLSRSSS--------PDLSSSSKLTASRKSTGQLNMNPGTT--------SGNTATAERSRHQRSFSVPKKFG--VIDRSSDPPRSATLDRIQACTQQG-LSSKTRSSSS-----LKDSLT-----------DPSHINHPTNLLATIFWVTVALMESDFEFEYLMALRLLSRLLAHMPLDKAENREKLEKLQAQLKWADFSGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSKISMVDASHAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSVQQPLLQVIYSLLSYMDLSVVPVKQFNVEVLKTIEKYVQSVHWREALNILKLVVSRSASLVLP-----SYQHSDLSKIEIHR--VWTSA----SKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPR-AMAVTRSTSSTSSGS-NSN-VLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLLEHQTSLVSSED--GAREQENMDDTNSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDM-QILEE-RQLSG---STPSLNK-------MHHEDSDESSEEE-DLTASQILEHSDLIMTLSPSEETN--PMELLTTACDSTPAEPHSFN--------TRMSSFDASLPDMNNLQISEGSKAEAVREEEDTTVH-------------------------------------------------------------------EDDLSSSIN-ELPAAFECSDSFSLDMTEGEE---------KGNRALDQFTLASFGEGDR-------GVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLAN----CKATFAGGSRDGVITCQPGDSEEK------------QLELCQRLYKLHFQLLLLFQSYCKLIG-QVHEVSSMPELLNMSRELSDLKKHLKEASAVIAAD-PLYSDGAWSEPTFT-------STEAAIQSMLECLKNNELGKALRQIRECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNQSLTEICTKLMELNMEIRDMIR----RAQSYRVLT-----------------TFLPDSSVSGTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIX3-1", "uniprot_id": "A0AB32TIX3_DANRE", "id": "A0AB32TIX3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------MSVKDVGSAGVVVDSKLDPCETQSRDGIVLVQMAS-----------------------------LSMHMFAPADFKGKFRKIQPRKRPTIIKEASPIG----KRPLPQ--------------------------------VSSALGERKGPVATMPVTVDPESKPGEYVLKSLFANFTTLSERKIRIIMAEP--LEKPLTKSLQRGEDPQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGLEDES------------------------------------------------------------HEYRP----RANTKSKND----------------EQQK--DYLMERRDLAIDFIFSLVLIEVLKQIPLHPLLDGLIQEVINLAFKHFKYKEGYLG-PNTTNMHIVADLYAEVVGVVAQSRFPAVRKKFISELKELRQKEQSPYVVQSTISLIMGVKFFRIKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHSLAGLFVEILVPVAATVKNEVNVPCLRNFVETLYDTTLDLSSRKKHSQALYPLVTCLLCVSQKQIFLNRWHVFLNNCLSNLK---------------NKDHKMARVALESLYRLLWVYMIRIKCESNTATQSRLTSIISTLFPKGSRSVVPRDM-PLNIFVKIIQFIAQERLDFAMKEIICDLLSVG-KSAKAFSLNPERMNIALRAFLVIADNLQQKDGEPPMPNTGATLPSGNTLKKKKTY--LSKTLTEEEAKLIGMALYYSQVRKAMDNILRHLDKEVGRCMMLTNAQMLNKEPEDMITGERKPKIDLFRTCVAAIPRILPDG--LSKIELIDLLARLTVHMDDELRLIAQNSLQSLLLDFSDWREDVLFGYTNFLLREVQDTQQGLQDSSVK-------LLLHFLTQWRLAIQAPGK---------------------------------------------------RSAEMGSQSSGSSRLAPDR----------------------SPHSTVLHAVEGLALLLLCSCQTSTRKLAVSVLREIRLLFTAIGQ-AEDDDKSMIEVMDQLAPSVLDSFVHVAVSDSATLPLSHH-VDLQWLVEWNA----------------RLVNSHYDVKSPSHVWIFAQSVK---DPWVLCLYSFLRPEHLPKHCPTALSYAWPYAFTRLQLLMPLVDPN-----------SPVYAKKTSTPGSA-DGYVTLWRNYLIMCLGVAKPSIMSPG--------HLRASTPEI-MATTPDGSVT--YDNKVIGTPSVAWLLKQLVPLMRSESLEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADSGVISDSTNGALERDSLALGALFLEYVDLTRMLLEAENDKELDILKDMRAHFSGMVANLIQCVPVHNRRLLFPQQSLRHHLFILFSQWAGPFSVMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSTDGYLYKWLDNILACHDLRVHRLGCEVVILLLELNPDQVNLFNWAVDRCFTGSYQLASGCFKAIATVCGSRNYPCDIVT-LLNLVLFKSSDTSREIYEISMQLMQVLESKLS---VYSKRTVGQKSGSILYGTHGPLPPLYSVSLFQLSNQLACMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLNNIELVDTGLLPPASS----PCTPEEEAREQADNLGITHRLKGNGWGSLQATSLVLNNLMFMTAK----------------YGDEVPGPEMENAWNALVSNDKWSNNLRITLQFLISLCGVSSDTTLLPYIKKVVIYLCRNNTIQTMEELLFELQQTDPVNPVVLHCDNPPFYRFAASNKTSVVASGTTSS---SNTVVAGQENFQDT-------DEAKITR---ETEERLSS-AARAHNRLESRYSNSSGGSYDEEKNDPLPPYAA--------------------------WLISVLESNRPQSLPMPVNGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHALFLGLDHYRPEVFEHSKRLLLHLLIALSCNNNFQVIASVLLLTREIGDNKTLTVKSSYQPEYVYTGGFDFLR--------------------------------EWQASPVADSGLSSSSTSSSVSLGGSIGNLPQITADLEELDESSTESEEKT--------------NKLIEFLTTSAWSTVLSLLRAFGPLWCHEDITPKNLNSKSAEQLTNFLRHVVSVFKESKS-DFHLEHQLSDVALQTALCSSSRHYAGRSFQIFRALRQPLSAHAVSDLLSRLVEVVGEHGDEVQGYVMEILLTLESVVDNLAECLNNSELMAALTRDSS--------PDFLVSGKLNLNRKSTGQINLLQEAG-------------TNERNRHQRSYSVPKKFGESGENSSSNPPRSATLDRIQACTQQG-LMRSARSTSSNSTRADTSVIT-----------DPSHSSHPVNLLATIFWVAVSLMESDFEFEYQMSLRLVHKLLARVPLDLQENRERLEKLQAQLRWSGFSGLQQLLLKGFTSPTTNDLTLQLFCQLTPVSRVPVVDTSQAIGFPLNVLCLLPHLVQHFGSPTQFCKESAERIAQVCLEEKDKNAKLSNLAHVMTLYKTRSYTRDPFSWVNVVCRYLHEAFSDITLSLVTYMAELLDKGLPSMQQPLLQIIYSLLSHMDLAGIQVKPFNVEVLKTIEKFVQTVHWKEALNILKLVVSRSASLSLP-----SYTHGDLAHLEVSRM-MWDGS----SKALPGKTMEFHFDISETPVIGRRYDDLQGSGGRDGKAR-AIAVTRSTSSTSSGS-NSNTVLVPVSWKRPQSSQKRTREKLVNVLSLCGQEVGLTKNPSVIFSSCGDLDLMEHQPSQVSSED--GTR-EDTLDDTTSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSTDLT---ELLEE-SQHSD---ITPCIGIGIGIGLHDPQRDSDDSSEEE-SNSTSQSLSHSQLTMNLSPSEDTN--HTDSLSTSYDTTSADPNSLN--------AATPCLGTSLPDDHIIPP-------VLPEDEESNIQ-------------------------------------------------------------------EDDMPFGVN-DLPMRFDCGSSTNLDLPAELN---------RAGINQNPNSLPSYHFGEDRDDLDELGFPPPPSPFFSAILAAFQPAVCDDSEEAWRSHVNQLMCDTDGSSAVYTFHIFSAMFQNMQNKFCSLTSDASTYLGEGLRGIGSKFVQSSDMLALCSDCPMLYVDAETIVSYGLLEKMKFSVLELQEYLDTYNTREEAVVSWLQN----CKATFPRFPDDGVITCQPGDSEEKQME------TLAQLELCQRLYKLHFQLLLLFQSYCKLIG-QVNTISSVPELWNMSRELSDLKNCLRLAEASLAGD-LEDRHRHGSQSIFS-------SSETAVQAILECLNNNDFSMAIRYTQECRRIWPN--------DIFGGGSED------EIQTLLNVYFRHQTIGQTGTFALVGSNKDMSEVCTKIMELNGEVRDMIR----RAQGYQVIS-----------------SSLVDSSVSGVSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9NYQ0-1", "uniprot_id": "A0A8M9NYQ0_DANRE", "id": "A0A8M9NYQ0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MEIQSYSERSYSELN----EENDGIEVVSMAS-----------------------------VPEDLMLSGDFRGKFKKIRYRKR----ASILSSSPGYTKPPVPP--------------------------------VCCSQGE-KGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEP--LEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDES------------------------------------------------------------HEYRP----RSNTKSKND----------------EQQK--DYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHG-PNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLK---------------SKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDM-PLNIFVKIIQFIAQERLDFAMKEVIFDLLFVG-KPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTF--LSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDG--MSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLK-------LLLQLLTQWKLALLSTNKSPDTS--------------------------------------------KICSAELLQSSS-GSRLPAEW----------------------TSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQ-TEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQH-ADLQWLVEWNG----------------SLVGSHYDVRSPSRVWILAQSLK---EPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPS-----------NPVNAKKTSSAGSA-DTYVSLWRNYLILCFGVAKPSIMSPG--------HLRASTPEI-ITPSPDSNSS--YDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVT-LLNLVLFKASDTNREIYEIAMQLMQILEAKLS---VYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSG----PSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAK----------------YGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSS---SKTLVCCQENIPDA-------DDSPITK---ECDDRLSN-ILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAM--------------------------WLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPD-FYTGGVDFLR--------------------------------NGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKS--------------SKLIEFLTT----------RPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKS-DIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVIL-RASS--------PDLPSSGKLTLNRKSTSQLELIPGSA------------TASERIRHQRSYSVPKRFG--EAERSSDVPRSATLDRIHHHQSNI-SKLRSLSSSSSR---DNVVST-----------DPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEK--NSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSP-----SSPQSNSSSVDVRR--VWDTP----SKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSED--GTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEA-QPLEEDSQLSG---SSPSLCP-------IIHDDSDESSEEE-SLTASQILSASQLNVSLSPTEDLN--PMDSPPVSFDNTQADQIPLS--------TSTPSFEIPLPEGSNHRAEDS------AEEEEGIVN-------------------------------------------------------------------ENDISLCIC-ESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCN----CKASFPKCSEDGVITYQPAETEEKQME------YLAQLELCQRLYKLHFQLLLLFQSYCKLIG-QVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFS-------SSEAAVQAILESLKNCDLSRAIRYIRECRKMWPS--------DIFGSSSEN------EIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIR----RAQGYRAIT-----------------AFLPDSSVTGISL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F8VQ05-1", "uniprot_id": "F8VQ05_MOUSE", "id": "F8VQ05-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEP--LEKLLSRSLQRGEDLQFDQLVSSMSSVAEHCLPSLLRTLFDWYRRQNGTDDES------------------------------------------------------------YGYRP----RSSTKSKGD----------------EQHRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSG-TNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLK---------------NKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDT-PLNIFVKIIQFIAQERLDFAMKEIIFDLLSVG-KSTKTFTINPERMNIGLRVFLVIADSLQQKDGDPPMPTTGVILPSGNTLRVKKIF--LNKTLTDEEAKVIGMSVYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDG--MSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVK-------MLVQLINQWKQAAQMYNRT--------------------------------------------------QDSQHGIANGGPHPPPLER----------------------NPYSTVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEV-PKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSVDLQTLADWNS----------------SPISHQFDVISPSHIWIFAHVTQG-QDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDIN-----------SPINAKKVNATTSS-DSYIGLWRNYLVLCCSAATSPSPSAP------AGSVRCSPPET-LASTPDSGYS--IDSKIVGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGVFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDSETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSSLMYWAVDRCYTGSRRVAAGCFKAIANVFQNRDYQCDTVM-LLNLILFKAADSSRSIYEVAMQLLQILEPKMF---RYAHKLEVQRTDGVLS-QLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQAMLHYLLPWMNNIELVDLKPLPSGRR---QDEDEDDSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAK----------------YGDELAWSEVENVWTTLADG--WPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSCKIPSVTSGTTSS---SNTMVAPTDGNPDSKALKENFEESYVHL---DIYGGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSN--------------------------WRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETASPGLPLHRCNIAVILLTDLIIDHSVKVEWGSYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSDIRTVASVLLRDKEFNEPRVLTVKQTAHSDYTFTAGINDFTP-------------------------------DYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLHTTLLGEVDLSVEQDGKV--------------KTLMEFITS----------RKRGPLWNHEDVSSKNPSIKSADQLATFLKHVVSVFKQSNAEGIHLERHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLSADTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQSSY--------HDPVMGNKYAANRKSTGQLNLSTSPI---------NSSGHLGCNGDTRSNSLRLSLVG---DRRGDRRRSNTLDITDGRINHGGSLARTRSLSSLR---EKGVY------------DTQPPTEPSNLMATIFWIATSLLESDYEYEYLLALRLLSKLLTHLPLDKSESREKIENVQSKLKWSNFPGLQQLFLKGFTSVSTQEMTVHLLSQLISVSKHTLVDPSQVSGFPLNILCLLPHLIQHFDSPTQFCKETASRIAKVCAEEK--CPTLVNLAHMMSLYSTHTYSRDCSNWINVVCRYLHDSFSEATFSLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSAAPVKQFNLEIIKIIGKYVQSPYWKEALNILKLVVSRSASLVVPNDIPKAYGVD-VGSPEISFAKIFNNV----SKELPGKTLDFHFDISETPIIGNKYGGQHSAAGRNGKAK-VIAVTRSTSSTSSGS-TSN-ALVPVSWKRPQLSQRRTREKLMSVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEDIIQEEEVAVEDNSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGD--TPSLQEYPCSS---STPSLTLTN-------QEDTDESSEEEAALTASQILSRTQMLNSDCVTEDMMPEHQDLLQ-SQDSASSNTTEDV----LQIRDETPSLEACLDNAS-SQLPEGTSSVLKEEHVTAFEDEGSY--------------VIPDQQDP-------------------------------LVCRGILDLEETDMPEPLAPESYPESICEEDVTLALKELDE---------RCEEEEADFSGLSSQEEDEQDGFPEVQTSPLPTPFLSAIIAAFQPMAYEDEEEAWRCHVNQTLSDTDGSCAVFTFHVFSRLFQTIQRKFGEITKEAVGFLGESLQRIGTKFKSSLEVMMACSECPTVFVDAETLMACGLLETLKFGVLELQEHLDTYTTKREAAEQWLDN----CKRTFGANEDIYRMNTNAH-----------------ELELCRRLYRLHFQLLLLFQAYCKLIN-QVNTIKNEAEVINMSEELAQLEGILKEAEAASENE-----EIDISKAAQT-------TIETAIHSLIETLKNKEFVSAVAQVKAFRTLWPN--------DIFGSCDDD------PVQTLLHIYFHHQTLGQTGSFAVISSNLDMSEANCKLMELNLEIRESLR----TVQSYPLLA-----------------QTKPVGNMTSTGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQY4-1", "uniprot_id": "D3ZQY4_RAT", "id": "D3ZQY4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MLGVTNSTFLPSSLRHSTLCYISGVTLLLFPSAPSSVPVKFKP-----------------------------QAGEASRWILSKFGVFSTNAVPHPQSLSASAPVSKVNKFCATSN--------------------------------FHSALGR--KSTIMSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEP--LEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTDDES------------------------------------------------------------YGYRP----RSSTKSKGD----------------EQHRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSG-TNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVMMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKMPSNNSIRKQIETLQNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDT-PLNIFVKIIQFIAQERLDFAMKEIIFDLLSVG-KSAKTFTINPERMNIGLRVFLVIADSLQQKDGDPPMPTTGVILPSGNTLRVKKIF--LNKTLTDEEAKVIGMSVYYPQVRRALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDG--MSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVK-------MLVQLINQWKQAAQMYNRT--------------------------------------------------QDSQS-ISNGGPHPPPLER----------------------SLYSTVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEV-PKGDEELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSVDLQTLADWNS----------------SPISHQFDVISPSHIWIFAHVTQG-QDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDIN-----------SPINAKKVSTTTSS-DSYVGLWRNYLILCCSAAASPSPSAP------AGSVRCSPPET-LASTPDSGYS--IDSKIVGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSSLMYWAVDRCYTGSRRVAAGCFRAIANVFQNRDYQCDTVM-LLNLILFKAADSSRSIYEVAMQLLQILEPKMF---RYAHKLEVQRTDGVLS-QLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQAMLHYLLPWMNNIELVDVRPLPSGRR---QDE-EDGSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAK----------------YGDELAWSEVENVWTTLADG--WPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSGCKIPSVTSGTTSS---SNTMVAPTDGNPDSKALKENFEESFVHL---DIYGGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSN--------------------------WRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETASPGLPLHRCSIAVILLTDLIIDHSVKVEWGSYLHLLLHAVFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSNIRTVASVLLRNKEFNEPRVLTVKPTAHSDYTFTAGINDFTP-------------------------------DYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLQATLLGEVDLSVEQDGKV--------------KTLMEFITS----------RKRGPLWNHEDVSSKNPSIKSADQLTTFLKHVVSVFKQSNAEGIHLERHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLSANTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSY--------HDPVMGNKYAANRKSTGQLNLSTSPI---------NSSSHLGCNGDTRSNSLRLSLVG---DRRGDRRRSNTLDITDGRTNHGGSLVRTRSLSSLR---EKGVY------------DTQPPTEPGNLMATIFWIATSLLESDYEYEYLLALRLLSKLLTHLPLDKSESREKIESVQSKLKWSNFPGLQQLFLKGFTSVSTQEMTVYLLSQLISVSKHTLVDPSQLSGFPLNILCLLPHLIQHFDNPTQFCKETASRIAKVCAEEK--CPTLVNLAHMMSLYSTHTYSRDCANWINVVCRYLHDSFSEATFSLVTYLAELLEKGLASMQQSLLQIIYSLLSHVDLSAAPAKQFNLEITKTIGKYVQSPYWKEALNILKLVVSRSASLVVPNDIPKAYGVD-VGSPEISFAKIFNNV----SKELPGKTLDFHFDISETPIIGNKYGGQHSAAGRNGKAK-VIAVTRSTSSTSSGS-TSN-ALVPVSWKRPQLSQRRTREKLMSVLSLCGPESGLPKNPSVIFSSNEDLEVGDQQTSLISTTEDIIQEEEVAVEDSSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGD--TPSLQECPCSS---STPSLTLTN-------QEDTDESSEEEAALTASQILSRTQMLNSDCVPDDLMPDHQDLLQ-SQDSASSNTTEDV----LQIRDETPSLEACLDNAS-CQLPEDTSSVLKEEHVTAFEDEGPY--------------LIQDQQDP-------------------------------LVCRGILDLEETDMPEPLAPESYPESVCEEDVTLALKELDE---------RCEEEEADFSGLSSQEEDEQDGFPEVQTSPLPTPFLSAIIAAFQPMAYEDEEEAWRCHVNQTLSDTDGSCAVFTFHVFSRLFQTIQRKFGEITNEAVGFLGKSLQRIGTKFKSSLEVMMTCSECPTVFVDAETLMACGLLETLKFGVLELQEHLDTYTTKREAAEQWLDN----CKRTFGANEDIDRINTNAH-----------------ELELCRRLYRLHFQLLLLFQAYCKLIN-QVNAIKNEAEVINMSEELTQLEGILKEAEAASENE-----ETDISKAAQT-------TIETAIHSLIETLKNKEFVSAVAQVKAFRTLWPS--------DIFGSCDDD------PVQTLLHIYFHHQTLGQTGSFAVIGSNLDMSEANCKLMELNLEIRESLR----MVQSHPLLA-----------------QAKPVGKTASAGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94915-1", "uniprot_id": "FRYL_HUMAN", "id": "O94915-1", "name": "Protein furry homolog-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEP--LEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDES------------------------------------------------------------YEYRP----RSSTKSKGD----------------EQQRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSG-TNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLK---------------NKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDT-PLNIFVKIIQFIAQERLDFAMKEIIFDLLSVG-KSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSGNTLRVKKIF--LNKTLTDEEAKVIGMSVYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDG--MSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVK-------MLVQLINQWKQAAQMHNKN--------------------------------------------------QDTQHGVANGASHPPPLER----------------------SPYSNVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEI-PKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSIDLQTLAEWNS----------------SPISHQFDVISPSHIWIFAHVTQG-QDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDIN-----------SPINAKKVNTTTSS-DSYIGLWRNYLILCCSAATS-SSSTS------AGSVRCSPPET-LASTPDSGYS--IDSKIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSGRVAAGCFKAIANVFQNRDYQCDTVM-LLNLILFKAADSSRSIYEVAMQLLQILEPKMF---RYAHKLEVQRTDGVLS-QLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTARR---HDEDEDDSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAK----------------YGDELAWSEVENVWTTLADG--WPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSS---SNTMVAPTDGNPDNKPIKENIEESYVHL---DIYSGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSN--------------------------WRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETSSPGLPLHRCNIAVILLTDLIIDHSVKVEWGSYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSNIRTVASVLLRNKEFNEPRVLTVKQVAHLDYNFTAGINDFIP-------------------------------DYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLHTTILNEVDISVEQDGKV--------------KTLMEFITS----------RKRGPLWNHEDVSAKNPSIKSAEQLTTFLKHVVSVFKQSSSEGIHLEHHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTATTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSY--------HDPIMGNKYAANRKSTGQLNLSTSPI---------NSSSYLGYNSNARSNSLRLSLIG---DRRGDRRRSNTLDIMDGRINHSSSLARTRSLSSLR---EKGMY------------DVQSTTEPTNLMATIFWIAASLLESDYEYEYLLALRLLNKLLIHLPLDKSESREKIENVQSKLKWTNFPGLQQLFLKGFTSASTQEMTVHLLSKLISVSKHTLVDPSQLSGFPLNILCLLPHLIQHFDSPTQFCKETASRIAKVCAEEK--CPTLVNLAHMMSLYSTHTYSRDCSNWINVVCRYLHDSFSDTTFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSAAPAKQFNLEIIKIIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKTYGGD-TGSPEISFTKIFNNV----SKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPK-VIAVTRSTSSTSSGS-NSN-ALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEDINQEEEVAVEDNSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGD--TPSLQEYQCSS---STPSLNLTN-------QEDTDESSEEEAALTASQILSRTQMLNSDSATDETIPDHPDLLLQSEDSTGSITTEEV----LQIRDETPTLEASLDNAN-SRLPEDTTSVLKEEHVTTFEDEGSY--------------IIQEQQES-------------------------------LVCQGILDLEETEMPEPLAPESYPESVCEEDVTLALKELDE---------RCEEEEADFSGLSSQDEEEQDGFPEVQTSPLPSPFLSAIIAAFQPVAYDDEEEAWRCHVNQMLSDTDGSSAVFTFHVFSRLFQTIQRKFGEITNEAVSFLGDSLQRIGTKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFGVLELQEHLDTYNVKREAAEQWLDD----CKRTFGAKEDMYRINTDAQQMEIL-----------AELELCRRLYKLHFQLLLLFQAYCKLIN-QVNTIKNEAEVINMSEELAQLESILKEAESASENE-----EIDISKAAQT-------TIETAIHSLIETLKNKEFISAVAQVKAFRSLWPS--------DIFGSCEDD------PVQTLLHIYFHHQTLGQTGSFAVIGSNLDMSEANYKLMELNLEIRESLR----MVQSYQLLA-----------------QAKPMGNMVSTGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I3F5-1", "uniprot_id": "A0AC58I3F5_DANRE", "id": "A0AC58I3F5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MEFLKSLVPTVISGDGGMQAADTAGVCPRETGPRLLRMKRLISSN-----------------------------EEEQDGSSPPSRPVVRLQRHRVKASVPVSNSSVSRRGTSPSAPP--------------------------------SWEKRSL--HPATMSSITIDPELKPGEFVIKSLFAEFAVLAEKKIEVVMAEP--LEKLLSRSLQRGEDAQFDQLISSMSSIAEHCLPSLLRTLFDWYRRQSGTEDES------------------------------------------------------------YEYRP----RSSTKSKGD----------------EQHRDKDYLVERRDLAIDFMFCLVSVEVLKQIPLHPVPDTLVQEVLNLAFKHFKHKEGYSG-PNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFITELKELRLKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLVTCLLCVSQKQFFLNNWHIFLQNCLSHLKMPSNNSIRKQIETLQNKDPKMSRVALESLYRLLWVYIIRIKCESNTTTQSRLLSIVTALFPKGSRSVVPRDT-PLNIFVKIIQFIAQERLDFAMKEIIYDLLCVG-KSHKTFTINPERMNIGLRAFLVIADSLQQKDGEPPMPTTGVILPSGNTLRVKKIF--LNTTLTDEEAKVIGMSLYYPQVRKALDNILRHLDKEVGRSMSMTNVQMSNKEPEDMITGERKPKIDLFRTCVAAIPRLIPDG--MSRQDLIELLAKLTIHMDEELRGLAFTTLQALMVDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVK-------MLLQLISQWRQAVQSSNRC--------------------------------------------------HDSQS-------PSLPLER----------------------SPLWTVLHVVEGLALVVLCSCRPATRRLAVNVLKEVRSLHTALGI-AKGDEELAIDVMDRLSASVLESFIHLTGADQTSLLYCPSGIDLQTLAEWSS----------------SPISHQFDVVSPSHIWVFAHVTQG-QDPWVISLSSYLRQENLPKHCPSALSYAWVFASTRLQLLSPQVDIN-----------SPINAKKVNSMSSSSDSYVGLWRNYLILCCSSATSSSSSSSSSSSSAPGSVRCSPPET-LASTPDSGYC--YDSKIISIPSPSSLFKHVVPMMRSESMDITESLVLGLGRTNPVAFRELLEELNPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADSGVISQTVSGGLDGESHSLNSTLLEYVDLTRQLLEAENDKDSDTLRDIRSHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDRKVHQLGCEAVMLLLELNPDQSNLMFWAVDRCYTGTRRVAAGCFRAIANVFHNRDYQFDTVV-LLNLILFKAADSSRDIYEVAMQLLQILEPKLF---RYAHKLEIQRTDGVLS-PASPLPHLYSVSYYQLSEELARTYPELTLPIFSEVSQRIQTAHPGGRQVMLHYLLPWMNNVELVDFKPSVRRQEEPSSAEEEEDAHERELMMVNSRRWLKGEGWGSPHATTMILNNLMFMTAKLQDACCMENGMSCSAQYGDEFAWSEIENVWTTLADS--WPKNLKIILHFLISMSGVNSEPSLLPYVKRVVVYLGRDKTMQLLEELMYELELTDPVSSAVTHMDNPPYYRITSSYKIPSVTSGTASS---SNTMVPGPDGHHDSKLKDSNIEDSYTHL---DIYTGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPVYAN--------------------------WRLKVMDHNRPEPLPFPPTGGCWSPLVDYLPETTTPGVSLHRCNIAVILLTDLIVDHGVKVEWSAYLHLLLHSIFIGFDHQHPEVYEHCKRLLLHLLVVQGTNSSVQSLASVLLRNRELNEPRVLTVKPTLQ-EFNLTG-VTELMP-------------------------------DYQPSPMTDSGLSSSSTSSSISLG--SSALPHLPPTLLNEVDLSAEQDEKV--------------KNLIEFISS----------RKRGPLWNHEDVSPKNPNIKSADQLSVFLRHVVNVFKQTPS-GFQLEQELSEIALQTALSCSSRHYAGRSFQIFRALKQPMTASTLSDMLSRLVETVGDPGEEAQGFVIELLLTLEAGIDTLAETMKSYDLLTAISQAS---------HDPLHGTKFANNRKSTGQLNLGSSFL---------HAH-----YSHARSNSLRASLMG---ERMGDRRRSNTLDIADRLGGSHGNLARTRSLSSLR---EGGVRGDGGGGTGGGSGEVVPQTDPTNLMATVFWIATSLLESDYEFEYLLALRLLNRLLAQMPLEKADSREKLERVQGKLKWYNFPGLLTLFLKGFTSAATQELTIHLLSKLITVSRHTLIDPSQLAGFPLNILCLLPHLIQHFDNPTGFCKETADRIAKVCAEEK--SATLANLAHMMSLYSTHSYSRDSTNWINVVCRYLHDAFAEITFNLVTYLAELLEKGLNSMQQSLLQIIYSLLSHIDLSAAPVKQFNLEIMKIIGKYVQSPYWKEAQNILKLVVSRSASLVVPDEVQRSYSTESTGSPEIAFTRIFNNS----SKELPGKTLDFHFDISETPIIGHKYGDQRSAAGRNGKPQ-VIAVTRSTSSTSSGS-NSN-GLVPVSWKRPQLSQRRTREKLMNVLSLCGPESGMPKNPSVVFSSNEDLDAGDQQTSLIPTVEEVTREEEAQAEDAGSEQQFGVFKDFDFLDVELEDGEGESMDNFNWGVRRRSLDSIDKGDGDTPSLQDCQYSG---STPSLIQP---------EDTDESSEEE-VLSASQILTRSNLLNSDSATDDAISNHMDSLQQSQESSSSVLTEEATPTPLLHRPDSPAHETARSDSNSSQLPEDASVTAGDELSSSVSEDTGFGSAPPLPSDPPELCDLHDSQDPTDDLDPAPPPPPAMDSPPGSLFDDEPGITPSVIDTTLDSMCEEETVLPLVLNSAPDSVCEDDVTLALKELDD---------RCEEEEADFYGLSSQDEGDADGFPELQASPPPSPFLSAILAAFQPVAYDDEEDAWRCHVNQMLSDSDGSSAVYTFHVFSRLFQHIQRKFDSITHSSVRFLGEGLQRMGNQFLSSLEVMTSCSQCPTVLLDAETLVSCGLLETLKFSVLELQEHLDTYNSKREAAEQWLDN----CRKTFGDKDSNQRPNTQAQQMEML-----------AELELCRRLYKLHFQLLLLFQAYCKLIS-RVDTIKREAEVTNMSEELAILESCLKEAESVNDEQ-----DIGEFEVDQS-------STETAIHSLIESLRARDFCTAITQVKAFRCLWPN--------DIFGSDRDD------AVQTLLHIYFRHQTLGQTGCLAVVGPSRDLSQASARLMELNLQIREALC----QAQTHPHLQSHQTHIQSPTPTGHIQTQIDTQNTVLSTGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT28-1", "uniprot_id": "FRY_DROME", "id": "Q9VT28-1", "name": "Protein furry", "aln": "MDQLELQDDLFGLEAGVAGTNQNPNEQHLSDPAASPSTSSPANNNATAGAATTSTATVITAVGGAGGGVAAAGVGVVTPTKSPQRNAFQEDAYQANLAGGDSVDNIESAQLDGGNPSGGSPGQRHSINSAEYTSTPKTTRSGPNGSTTASGTTSPINYQLPGDDYPYGIEYESQQLLYQQQQQQQQQQSQQQQQQQQQQQQQLPVGDVEQSSAVTYQSLPVSRQSYASPPALIIPQRQSLLPWGAHSRSSIINVLPSYTQAEMHALAARVASVETSAPRPGEIVMRNLFSDFTAQAEKKIELVMLES--ADKNLSKLLQRGEDQQFDQLLSALGSVAEHCLPSLLHTLLAWHRRQLSDMEIK------------------------------------------------------------NDLKKPAPSGSSSQAATN----------------KPTVDLDFQLQRREAAVEFIFCLALIEILKQLPYHPGHEDLVRSIENLAFKHFKYKDGLQNNPNALNIHMIADLYAEVIGVLAQSRFASVRKRFMSELKELRGKEVSPTTTQSIISLLMGMKFFRVKMVPIEEFEASFQFMHECGQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCVKNFVELLYVQTLDASTKSKHRLALFPLVTCLLCVSQKTFFLTNWHYFLAMCLSNLK---------------NRDAKMSRVALESLFRLLWVYMIRIKCESNSATHSRLQSIVNSLFPKGSKGVVPRDT-PLNIFVKIIQFIAQERLDFAMREIVYDLLCVG-RSIK-LILNPERMSIGLRAFLVVADSLQQKAGEPPMPRTVPVLPSGNTLRVKKTFNKMYVLLTDDTARSIGMSTYFPHVRRVFVDILRALDVHYGRPLMMTNTQNQNKEPDEMLSGERKPRIDLFRTCVAAVPRLIPDT--MTPHELVDMLSRLSVHMDEELRILTHQSLTTLVIDFPDWRQDVVHGYTQFLVRDVTDTYPQLLENCTR-------ILFTFLNIWRCATNVNGNNTTSAPSGATNVVNTSQAKMTTATTTTTVVQATVVQVTSAPAKDTASSQLSKQQHLNTASSAASSITTSSGMSSITQHTVLNMASDVGKKNEIPLATTLHFVEGFALVLLCNYRTYLRKLAALILKEVKNLMRALGI-PETEP-PLIDVMDRCVPGIIEKCLPQLPQTEKTAILNANCIDLQWIAERSSGVWLAGLTDDNSKSSTSTLNLSQSSSTPNASATAASSPQLPFDPWATCLFGLLERQNVLQQCPSAVAQAWPICFTRLNALYSVIDPTPVSDNRASLLRSSAPTKKVPTESQK-DSYLRLWRN-QVACAMRLVPQIPSVA---------VRCASPDLSLSSSPDSLNADRSDKSAMGSASPQALYKLVVPLLRCEVVDVRDAAVNALGLINHDALKDLMEELVVYIREAVDCKQENMRRRRRRDALRLQVVRVLEKIAENGTFGVST-CVLERDTMSLHPTFVLYISGAMGYLTSETDKDNLSIREVKAHFCNFIRKMIKNFPLEACATLLSR-VLKRNLFNLFAAWCGSFSKPLG-YTMQSDHTLEEEKLQFSALQAMSALLCCGQIFNPSYLQDDSIIYKWLDMLLTSKNEKIYQLARDTVVLLLESNPDIGQLLEWVIDRCYTSTPREADACFLALASIFSAKEYPCDHYTSVITVTLLMTGCPRVEVHATALQLLQILDKRFFGSVVGTLHSDSDKEDDKVGTLDVLLSSAYCRSQRFLSKQLAQLRPELTMSIFSEITHRFQSAREDVRALLLQCLLPWLQNMELVATSVPP------------ATPLSYIMYFPDSGTRGRREGTGSTEATEMILNNLFYITAK----------------FSDAHP-RDIEELWGTLCQF--WPNNLKVILRYLVIMSGMAP-TELLPYAKRVALYLVRSCPDRLLDELMAELQTVETLNCLIERTETPPFYRLTSMRKASSHSADGQAAGGINDSRIQDLAVEKGTIHTKRHSGEDPMKIGTCKSDSGIRAYTQAAAAAAAAAVTPGSSGNRPPRGADKIRAASGPSILPRPEDILINDPELRQEENVELRGTSDAAPNGHPHPLPMPEYGGYFAPLTEFLPDVSLPISGFHRCNVAVMLLTDIVVDGIPGIDWTLHLPLMLHILFLGLDHTRIIVREHCKQLCVNLLIVLAEHNDHLTVARILLNSETSKLDLGLTVPALPVIDNNFTELHQQFDSYLLHVSPQAAAYALQHNLSSSTIIAAHHQNLSQTPQSQQQTGSQNGQTTTPPGLTATPAALQINPNNSENSEVPLIHPDEHAPPQPGPSMPIAHVIKSLLKFLAQ----------DTCQPLWNYEDITAKVWAVKSAEQLSCFLKHMVKVFADSYP-QARIAERWAQTALQLGLSCSSRHYAGRCLQIFRALNVPINSRMLSDILSRLVETVAEQGEDMQGYVTELLLTLEAAVDSLDSDFRPLDVMKDIFKSTPNLNNKDGGPNSILPGKKSPSGMTPQSSNYSIPSHG------RSTSYSVSYCGRKANNSPCDKQVELRNRSSGIDLERSVVCKFGVGGGGAGSALSRSRSAQSLK------MLG-----------DTATQDDKMTILAQLFWLSVSLLESDYEHEFMLALRLLTRVLHRLPLDRPDARDKVEKLQQQLKWTAYPGVHALLLKGCTHSATYEPTITLLSQFAPLLTLPVCDPTQSCAFPMNVIALLPYMLLHYEDANEICIRSAENIAQVSTELG---AKLENLGTVMTLYSRKTFCKESFQWTKCVVKYLHDTYAHMGLHMVAFLIEVLEKGPQQVQVPVLNVIHCMLHYVDLSAPQAQSINADLLRAIGKYLDTAYWKDSLKILKLIVTRSSSLQVVP-----PSDGSSAGLSFSFYGAYPDSDMFCKKELAGRTMEFTFDVSQTPLIGRRILLKTEEPVAGGAVS----TTGSSSLNSTLTNATTVTVAPSAAQQQTNVQMQQQRANTNVAALAAAAAAQHQQQQHAIGAGSSVVGTPNSPRRSASLS---PADTVPLSGWKRPWMSQCRVRECLVNLLTTCGQRVGLPKSPSVIFSQSSDLMERQSSAASSTEETSGPQGDLSSG--------------SRRDDGQPDFTVFKDFDFLEYEDSIAGESTDNFNWGVRRHQLFEGDEDRLNCGSGIGG---SIKGGHSSAFEDSFSDKTPILSKRKRQIADDSSDEEAESE-------------------------------------------------------------------SPLDEDHRQSFLKSGYSAVPPTSLSLRERRR---------RNSVSRSDTSGSSAGDLGD-------LTPCNASPHLPGIIR-FSAAIHDEAEENWRRQVQALLVNQPSAHTSELLQQLYRLIKELTFKTVNISKEAKKFFTGIGSQLGNRISLFTDLLSSRADPPQVWCSELQATSPKLFETLRFNVLEVQEHLETFFDRKDQVLECLDAVKTSCKLSLFNEADVAASGLELPSTSSIVYMPFDPASTEVVLDLGRSLYKLMFQLLLLIESNHKISSNVVNHFRMNEDMHDISDLYALVRDALVRYISEAELDCLESSTSTEGEHTPTPSPGLPMTPEEFEAVLTEHIDLQRWPSAIAHVRQYRRISTLNASGYQNVTIFSYNSADNRQKWDEISVILNAYAHGIMKDRTEAFIVSKSDSEVFEIYAILSENLYQVSSALTNMEISMKSYSAGSASG--------------NSHRSEQDIVTNL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40468-1", "uniprot_id": "TAO3_YEAST", "id": "P40468-1", "name": "Cell morphogenesis protein PAG1", "aln": "---------------------------------------------------------MASRFTFPPQRDQGIGFTFPPTNKAEGSSNNNQISIDIDPSGQDVLEEINEAPLNTFPLHQSVTDAPIIDIPSPTDMSEGTSLNNQLLLRQQQ-----------------------------QQGTGEGQALPPTFVEEQSDQNKISMLLPEQKQQRMQESAPP---------------------------------DITAKSVAEDYVTTLRQQMATDWKSPSEYALHILFTKFIRYAENKLNMCLQQLDMAEPPIVEILGEGVDPSFDEIIKSLGHIAKKKPKPVIDAMMFWRKTKSEAANSASEEMEKLLKEYEFEKAHPSQAHFLMNRRLSRSSSNTTSKYKHNNNTNNLPGMKRHVSSSFNNKVPLIKASSSNNSATSSPSIANSQLKSLENTIEVAKEEAFLADRKSLISIYILCRVLNEIVKQASSN-EEEDLSDKLEEIVFTQLKTTDPLSI-STSLIKSSNWNSFAELLGSMSEKKFLSVSDRFIADLEKIP-AYIPPELEPSTHLLILGMRYLKLRNYPLEKFEESADFMKSLSKFFAKTENFPVCLAYAEVTNQLLLPLAGSLTAEVNHPTWVEAMSTLLNTAKRLQADSKYWVSGFKLTVSILCASPPDLFSKQWLSLLEANASKVK---------------SKSLNERIIFAVGLSRLVWVYLYRCPETLNNTTRTLTKLLQLYLNTRKKENWITGDFGLLNPLTDALISIGFLHPNFLMEQALIPLIRQSFNGSNLENINYEKLILTINTYKGLLVTKER----PRFPEDDNRLYELNLNNITVNQVQEASSINHTEISDYFYKLFLLLDSSIGSEVWSPENQHQKQSSNAFSPFGFSFSNDNDSSKNKSLYVILFGTIIEAIPCCLSISRTIPYKSTIEILSRNAVHSEVIISSSSQNALRALASKKNPYTLITWFAKYSFDFDEKTQSSYNMSYLSSKEYNRLLILYVELLECWLEEFQSSNKEENKKETG-----------------------------------------LDGIRLLPIDAEQEESNETEK-------------------LEWKNTVTVIEEVEGNGLFFLCSHDAKIRRLGIQILRIIFKFDEAMMEKTEKLSNGHSRSSSHFAADRGTRLIDLLNECNTTTLINPHKATLSAVEKTRFS--------------------RLNSKYKRGLLIKLAESEYGVDAALWQRAFPKLLALVFKTCPMAMALCRSIVCIRLVQVHEIILRV-------------ANDVDFKLKNVLPETIVNQWKLYLIAACTSLTSTFDQKL--------HIPSNIPQHGRKKSQQ-----IFTVQHQKIKSAKSIFKMVLPLLNAKYIMIRDAIITGLSSMNINIFKAYVEAIDVFLVAWKEGSSNNQIR--------------VEMFHILTILSPYLKSDMIFNDEWILRKLSEFLQKTKQFLEKDSVQISYEYQSLRSYFAGLILSYYMAVREHPLIDELFPFQARASCFNFLKEWCG-----------YGEYEPISEERYAIMIKNTESGRDRTAITTGIEFQKNRLQMIVLETMVVLCSDPITQTLDDDLELPIVISFDTEDLLAWIEALFDSDNTTVKNLGVRALENLLDKNRENFKLFRDVAFQCVSHHSHPSVAVLYYTTLCKSVLKLDNL--VLDEDELVSLGLYGLVADKEDTRTFAVDLLSAVETKLHNSSYTKVFKERLANSSKTVYKSTAKEISSIFAELLSQDLCLRIFSSLVRILDLFP-------FEIKRDLLVLMVPWVNKFTLKSLEELDTFMVLNNLFYITID-----------------LNDSLPNEVEQLWISLGKGN-SFQNIHVSLEYIINSSMNHCNPLFVQYARDIVLYLANIPGGIGLLDTLLNNLEPKYMVPLAKHTFNEPMNNNKYSFLGNIWERLNYNG-----------------------------------------------------------------------------------------------------------------------------------------KRIIFSKAQLSIIFLVNLLTN--LSESVKAKIPLLLHMSICLLDHYVPLIHESACKIASTLIFGLAPSHEKSEETVKLLRN---------------------------------------------------------------------------------------------------------------------------------------------------KHALWSYDNLMKKG--ARSPKTMDLLIRNIISIFSDLDE----FQVTWQRIALKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDGNVDIQGFAMQILMTLNAIMAELDPTN--------------------------------------------------------------------------------------------------------------------------------------------------LISFPQLFWSITACLSSIHEQEFIEVLSCLSKFISKIDLDSPDTVQCLVAIFPSNWEGRFDGLQQIVMTGLRSANSLEITWKFLDKLNLLKDSRIIANTESR-LLFALIANLPRFLNAMDRKDFTGIQVAADSLIELANAY----KQPSLSRLIDSLAKNKFRSKKDFMSQVVSFISRNYFPSYSAQTLVFLLGLLFNKIGWIRVQTLEILKYVFPLIDLRRPEFIGVGADLISPLLRLLFTEYEAKALEVLDCVPNVSG------------------------------------SKMDKDVLRITMGNKDVKDGDNATTTLFGLPEDSGWSV----------------------------PMPTMTAATTRHNVHAVFMTCG--------------TGKSDEVSAHGSDDMDAVIEFHADGDYELGRMDTIVEFHADGDYDLGRMDTNDSISVAEEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DASLSHMWAELDNLDSFFTKDTN-----------------------------------------VPNISSKMGMGIPHGRSDSIETTRTDQTFSFESAPQLYDKKVSVILNRSLSRTPSNVSFKTHLADSFAVKINRNGKPRI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* .:: :* .* :*.*:.: : : : : . * .* * .**:::.::. ::: .:: ::: * : : : :..:: . : : :*:. :::. . *::** . : : * .: .:.*.::* .: ..: : :**::* ::: :* :* .:* ::*::: * * *::*:::::: *:*.** * :**:. .::* :.:: : : * : ::*:*:*.::. *** * : :. * : .: .*: : : : ..:**.* :* ..* :* *::* .:. : : .* **:***: * *..*: : * .: ... :. * ** :.. : *. : :* *.: : :: . . : :* *:: : :..: : . :: * :* * . * . . :.. : .: : . : . . . :: : ::. : ** * : *:* :. :. . :::*:: ::* : : : :* * . : . . * . : : : . : : . :: * .. . ..:. *** .*..**. *:*. :*: : : : .: .: . . : *. : . . : :. : : *. *:: . ** : : . : : *: : . . . : . *: : : . * : * ::*::. : : : :: : .:. * :: :* : : : :* * .* : :. : : : : ::. : * :. : :.::.:*. :: . . . : : * :: *.* .: . :: .: : :. : *: :: . : : : : * : . * .*: * :.. . *: .: . . : : . . : : .:*. . : . : .:: ::: :: . .: :: **. :.:. . : ::****:::* . : ::*: * :* . :*:: *.::: . . :: : : : ** . : : : : . : : . * . . : :..::::::.::: : . : *:** : :** : * . :: *:. . . : ** .** :::: * :*.. : ::::::.:* : : **: . .* ** * *.:*:**:* : : *:* ** :.:.: . : **:. : *:**:: : * :. :** .: :.* .* *: * : :.: :: *: : : : : . : *: :.:.* : : * :: : : : :. : : ::. :* :: * : . .*. :: ..: . : * :: :. :.:: :* : :: *::: :: :** .. :: : : : : : .: ::*. : . *. . : .: : :. .:. .. .* :. * .. : . : . : : : . . * :.. : . .: : * . . . : :. . : : : :: ", "identical_positions": 199, "similar_positions": 658, "identity": "5.24%" }, { "cls_id": "homologset.agr.SGD:S000001393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W5X5-1", "uniprot_id": "Q9W5X5_DROME", "id": "Q9W5X5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDTTPIFQSSFSIRSLL-----SVDKKEESPISK---------HNSG-------------------------SSFSSCSSS-----------------------------SSNSSSDSMAAKS---NAKPAFTYSALIVMAIW------SSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRA------LDDPGRGHYWALDP---YAEDLSIGETTGRLRR------------------------------------------------------------------------------------------------------------------------------------------------------------SNWQQNTGARPK---------------------------VTGHPYQR----MPYYGHGHG---------------------------------------------------------NGPYIKAHSAYFPIMDHQHHAAMVQ--HYQAMMHR------------------------------------------------------------------YQMMPHPHHHQHQH---------------------------------------------------------------------------------------QHQHPHSHFIQQ-----------------------SKPLHIQEPYHHTRYHLHQE---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32031-1", "uniprot_id": "SLP2_DROME", "id": "P32031-1", "name": "Fork head domain transcription factor slp2", "aln": "---------------------------------------------------------------------------------------------MVKIEEGLPSSEISAHSLHFQHHHHPLPPTTHHSALQSPHPVGLNLTNLMKMARTPHLKSSFSINSILPETVEHHDEDEEEDVEKKSPAKFPPNHNNNNLNTTNWGSPEDHEAESDPESDLDVTSMSPAPVANPNESDPDEVDEEFVEEDIECDGETTDGDAENKSNDGKPVKDKKGNEKPPYSYNALIMMAIR------QSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRH------YDDPGKGNYWMLDP---SAEDVFIGGSTGKLRRR-----------------------------------------------------------------TTAASRSRLAAFKRSLIGPMFPG------------------------------------------------------------LAAYPQFGQFLTYPPTAPS---------------------------LLASMYQRYNPFAPKGGPGHPGLPPG---------------------------------------------LPGLPGPPGPQGPPGPPPPPFVAPPTSSELYQRLQYQQLLHQ------------------------------------------------------------------HAAAAALAAHQRQLSVA--------------------------------------------------------------------------AASAASQPPPTHHHPHLAVGQAPL-----------------SPGGDSPGPSPQPLHKPVTVVSRNS--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32030-1", "uniprot_id": "SLP1_DROME", "id": "P32030-1", "name": "Fork head domain transcription factor slp1", "aln": "---------------------------------------------------------------------------------------------MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFD-------------------------------DELEDQLDEDQES-----------------------------EDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQ------DSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRS------YDDPGKGNYWILDP---SAEEVFIGETTGKLRR---------------------------------------------------------------------------------------------------------------------------------------------------------------KNPGASRTR---------------------------LAAYRQAIFSPMMAASPYGAP---------------------------------------------------------ASSYGYPAVP----FAAAAAAALYQRMNPAAYQAA------------------------------------------------------------------YQQMQYQQAPQAHH----------------------------------------------------------------------------------------HQAPHPAQMQG------------------------YPQQLNAELFQRMQFFGKFPSS------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "J3QP53-1", "uniprot_id": "J3QP53_MOUSE", "id": "J3QP53-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDSSQYPYNCFNDDADDYPAGSSDEEKR-----------------------------------------------------------------------LTRPAYSYIALIAMAIQ------QSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRT-----EGNDKGKGNYWTFAGGCESLLDLFENGNFRRRR--------------------------------------------------------------------RRRGPKRE--------------------------------------------------------------------------------------------------------------------------EAP-GPLEP-TARGSPGPDSA-----------------------------------------------------QAPDHEAQASPTT-----HRDIKFSIDY----------------------------------ILSSPDPFPTLRSSCHSQE-------------------ARYPALEPQQMSFQFWAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2PRP0-1", "uniprot_id": "FOXL3_HUMAN", "id": "A0A1W2PRP0-1", "name": "Forkhead box protein L3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDSSQYPYNCFNYDADDYPAGSSDEDKR-----------------------------------------------------------------------LTRPAYSYIALIAMAIQ------QSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRS-----EGHEKGKGNYWTFAGGCESLLDLFENGNYRRRR--------------------------------------------------------------------RRRGPKREGPRGPRAGG----------------------------------------------------------------------------------------------------------------AQGPSGPSEPPAAQGRLAPDSAGE---------------------------------------------------GAPGREPPASPAPPGKEHPRDLKFSIDY----------------------------------ILSSPDPFPGLKPPCLAQE-------------------GRYPRLEN--VGLHFWTM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LTI9-1", "uniprot_id": "A0ABK0LTI9_RAT", "id": "A0ABK0LTI9-1", "name": "Forkhead box protein G1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTLTTILPAAPTRKSGSQGQHTGDPGGRFQGSHRSGRGLCH--------------------------------------------------------------QNLTKTRESYIALIAMAIQ------QSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRT-----EGHDKGKGNYWTFAGGCESLLDLFENGNFRRRR--------------------------------------------------------------------RRRGPKSE--------------------------------------------------------------------------------------------------------------------------EAP-GPLQP-AARGSPGPDGT-----------------------------------------------------QAPDREAQARLVT-----HRDIKFSIDY----------------------------------ILSSPDPFPVLRSSCHSQE-------------------ARLSRETQSFIWRDMETFL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02360-1", "uniprot_id": "FOXL1_DROME", "id": "Q02360-1", "name": "Fork head domain-containing protein L1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MLPSCYANGSMLPDNEELVNSMLANPDYLRTQVSPNPLAPSAVGGAGMEGLMCGSFSPAFYYQGIDSFLALHNNIWGLPISF-----------------------------LHNSHRPEKPPFSYIALIAMAIS------SAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDS---SASDMFEQGNYRRRR--------------------------------------------------------------------TRRQRHCGHPNRYERES----------------------------------------------------------------------------------------------------------------GKDSNDGNSSAAEIRSPSEPLSDF---------------------------------------------------DIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRP------------------LPEIRECPDDVDASSSSSKAMQ-------------------SSMELHEELHSPSAFTPPLNRRET----------------------------------------------------------------------SSSGAPVLAEAFNGIKDVVDAPGSSPV---------------ASSNRSKTTLFTIDNIIGKP------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35582-1", "uniprot_id": "FOXA1_MOUSE", "id": "P35582-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "------------------------------MLGTVKMEGHE---------------------------SNDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPA-SFNMSYANTGLGAGLSPGAVAGMPGASAGAMNS--MTAAGVTAMGTALSPGGMGSMGAQPATSMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRS-------------------------------------------YPHAKPPYSYISLITMAIQ------QAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARS------PDKPGKGSYWTLHP---DSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKCEKQPGAGGG----------------------------------------------------------------------SGGGGSKGGPESRKDPS--------------------GPGNPSAESPLHRGVHGKASQLEGAPAPGP-----------------------------------------------AASPQTLDHSGATATGGASELKSPASSSAPPISSGPGALASVPPS------------------HPAHGLAPHESQLHLKGDPHYSFN----------------------HPFSINNLMSSSEQQHK-----------------------------------------------------------------------LDFKAYEQALQYSPYGATLPASLPLGS-------ASVATRSPIEPSALEPAYYQGVYSRPVLNTS------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55317-1", "uniprot_id": "FOXA1_HUMAN", "id": "P55317-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "------------------------------MLGTVKMEGHE---------------------------TSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPA-SFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNS--MTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRS-------------------------------------------YPHAKPPYSYISLITMAIQ------QAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARS------PDKPGKGSYWTLHP---DSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKCEKQPGAGGGGGSG------------------------------------------------------------------SGGSGAKGGPESRKDPS--------------------GASNPSADSPLHRGVHGKTGQLEGAPAPGP-----------------------------------------------AASPQTLDHSGATATGGASELKTPASSTAPPISSGPGALASVPAS------------------HPAHGLAPHESQLHLKGDPHYSFN----------------------HPFSINNLMSSSEQQHK-----------------------------------------------------------------------LDFKAYEQALQYSPYGSTLPASLPLGS-------ASVTTRSPIEPSALEPAYYQGVYSRPVLNTS------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23512-1", "uniprot_id": "FOXA1_RAT", "id": "P23512-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "------------------------------MLGTVKMEGHE---------------------------SNDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPA-SFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNS--MTAAGVTAMGAALSPGGMGSMGAQPAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRS-------------------------------------------YPHAKPPYSYISLITMAIQ------QAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNACFVKVARS------PDKPGKGSYWTLHP---DSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKCEKQPGAGGG----------------------------------------------------------------------SGGGGSKGVPENRKDPS--------------------GPVNPSAESPIHRGVHGKASQLEGAPAPGP-----------------------------------------------AASPQTLDHSGATATGGGSELKSPASSSAPPISSGPGGWICTPLS------------------P--TWLAPHESQLHLKGAPHYSFN----------------------HPFSINNLMSSSEQQHK-----------------------------------------------------------------------LDFKAYEQALQYSPYGATLPASLPLGG-------ASVATRSPIEPSALEPAYYQGVYSRPVLNTS------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07342-1", "uniprot_id": "FOXA2_DANRE", "id": "Q07342-1", "name": "Forkhead box protein A2", "aln": "------------------------------MLGAVKMEGHEH--------------------------AADWSTYYGE-PECYTSV--SNMNTGLG-MNSMNTYMTMSGMSSTANMTAANTMNMSYVNT----GMSP-SMTGMSPG-TGAMAG--MG-AGMTGMSAALSP-TMSPMAAQ-APSMNALTSYSN-MN-AMSPM-YGQSNINRSR-----DPKTYRRS-------------------------------------------YTHAKPPYSYISLITMAIQ------QSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRS------PDKPGKGSFWTLHP---DSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKCDKKLSKDPS----------------------------------------------------------------------------------RKTSE--------------------GGSNSSSES------------CNGNESPHS-----------------------------------------------NSSSNELKRSLSDMKSGQG---LSPDHAASPTSQAQHLLAQH------------------------HSVLAHEG--HLKPEHHYSFN----------------------HPFSINNLMSSEQQHHK-----------------------------------------------------------------------MDLKTYEQVMHYG-YGSPMAGTLSMG---------SMASKAGLD--SPDTSYYQGVYSRPILNSS------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35584-1", "uniprot_id": "FOXA3_MOUSE", "id": "P35584-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "------------------------------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------NPVPTMAPLNSYMTLNPLSSP-----------------------------YPPG-------------GLQASPLPTGPLAPPAPTAPLGPTFPSLGTGGSTGGSASGYVAPGPGLVHGKEM-----AKGYRRP-------------------------------------------LAHAKPPYSYISLITMAIQ------QAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARS------PDKPGKGSYWALHP---SSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKLEEKAKKGNS---------------------------------------------------------------------------------ATSASR--------------------NGTAGSATS----------ATTTAATAVTS-----------------------------------------------PAQPQPTP-SEPEAQSGDD---VGGLDCASPPSSTP-------------------------------YFSGLELPGELKLDAPYNFN----------------------HPFSINNLMSEQTS-----------------------------------------------------------------------------TPSKLDVGFGGYGAESGE---------------------------PGVYYQSLYSRSLLNAS------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32183-1", "uniprot_id": "FOXA3_RAT", "id": "P32183-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "------------------------------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------NPVPTMAPLNSYMSLNPLSSP-----------------------------YPPG-------------GLQASPLPTGPLAPPAPTAPLGPTFPGLGAGSGTGGSASGYGAPGPGLVHGKEM-----AKGYRRP-------------------------------------------LTHAKPPYSYISLITMAIQ------QAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARS------PDKPGKGSYWALHP---SSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKLEEKAKKGNS---------------------------------------------------------------------------------ATSATR--------------------NGTVGSATS----------ATTTAATAVTS-----------------------------------------------PAQPQPTPPSEPEAQSGED---VGGLDCASPPSSAP-------------------------------YFTGLELPGELKLDAPYNFN----------------------HPFSINNLMSEQTS-----------------------------------------------------------------------------TPSKLDVGFGGYGAESGE---------------------------PGVYYQSLYSRSLLNAS------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55318-1", "uniprot_id": "FOXA3_HUMAN", "id": "P55318-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "------------------------------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------TPVPTMAPLNSYMTLNPLSSP-----------------------------YPPG-------------GLPASPLPSGPLAPPAPAAPLGPTFPGLGVSG--GSSSSGYGAPGPGLVHGKEM-----PKGYRRP-------------------------------------------LAHAKPPYSYISLITMAIQ------QAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARS------PDKPGKGSYWALHP---SSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKLEEKVKKGGSG--------------------------------------------------------------------------------AATTTR--------------------NGTGSAAS------------TTTPAATVTS-----------------------------------------------PPQP-PPPAPEPEAQGGED---VGALDCGSPASSTP-------------------------------YFTGLELPGELKLDAPYNFN----------------------HPFSINNLMSEQTP-----------------------------------------------------------------------------APPKLDVGFGGYGAEGGE---------------------------PGVYYQGLYSRSLLNAS------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14734-1", "uniprot_id": "FKH_DROME", "id": "P14734-1", "name": "Protein fork head", "aln": "--------------------MQKLYAEPPPSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRS-------------------------------------------YTHAKPPYSYISLITMAIQ------NNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRT------PDKPGKGSFWTLHP---DSGNMFENGCYLRRQ--------------------------------------------------------------------KRFKDEKKEAIRQLHKS-------------------------------------------------------------------PSHSSLEATSPGKKDHE--------------------DSHHMHHHHHSRLDHHQHHKEAGGASIAGV-----------------------------------------------NVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQ------------------EELSAMMANRCHPSLITDYHSSMHPLKQEP---------SGYTPSSHPFSINRLLPTESKAD------------------------------------------------------------------------IKMYDMSQYAGYNALSPLTNSHAALG----------------------QDSYYQSLGYHAPAGTTSL----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64732-1", "uniprot_id": "FOXB1_MOUSE", "id": "Q64732-1", "name": "Forkhead box protein B1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPGRNT-------------------------------------------YSDQKPPYSYISLTAMAIQ------SSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRR------PDQPGKGSFWALHP---SCGDMFENGSFLRRR--------------------------------------------------------------------KRFKVLKSDH----------------------------------------------------------------------LAPSKP----ADAAQYLQQQA--------------------KLR-------------------LSALAASG---------------------------------THLPQMP------AAAYNLGGVAQPSGFKHPFAIENIIAREYK---MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMTSG-DYSAY---------GVPLKPLCHAAG-QTLPAIPVPIK-----------------------------------------------------------------------PTPAAVP---ALPALPAPIPTLLSNSP-------PSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99853-1", "uniprot_id": "FOXB1_HUMAN", "id": "Q99853-1", "name": "Forkhead box protein B1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPGRNT-------------------------------------------YSDQKPPYSYISLTAMAIQ------SSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRR------PDQPGKGSFWALHP---SCGDMFENGSFLRRR--------------------------------------------------------------------KRFKVLKSDH----------------------------------------------------------------------LAPSKP----ADAAQYLQQQA--------------------KLR-------------------LSALAASG---------------------------------THLPQMP------AAAYNLGGVAQPSGFKHPFAIENIIAREYK---MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMASG-DYSAY---------GVPLKPLCHAAG-QTLPAIPVPIK-----------------------------------------------------------------------PTPAAVP---ALPALPAPIPTLLSNSP-------PSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64733-1", "uniprot_id": "FOXB2_MOUSE", "id": "Q64733-1", "name": "Forkhead box protein B2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPGKSS-------------------------------------------YSDQKPPYSYISLTAMAIQ------HSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRR------PDQPGKGSFWALHP---DCGDMFENGSFLRRR--------------------------------------------------------------------KRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHHHPPQPPPPPPP---HMVPYFHQQPAPAPQPP-HLPSQPAQQPQPQS--------------------QPPQTSHPGKMQEAAAVAAAAAAAAAAAVGSV-------------------------------GRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIENIIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLSNVVGSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAF---------GVPVKALCHSAN-QSLPAVPVPIK-----------------------------------------------------------------------PTPALPPVTTLPPALSVPTASQQLPAP-------STVC-AAAASPTAPLLEPTAAGRADSKGSSLHSVLVHS-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7J9-1", "uniprot_id": "A0A0G2K7J9_RAT", "id": "A0A0G2K7J9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPGKSS-------------------------------------------YSDQKPPYSYISLTAMAIQ------HSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRR------PDQPGKGSFWALHP---DCGDMFENGSFLRRR--------------------------------------------------------------------KRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHHHPPQPPPPPP----HMVPYFHQQPAPAPQPP-HLPSQPAQQPPPQS--------------------QPPQTSHPGKMQEAAAVAAAAAAAAAAAVGSV-------------------------------GRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIENIIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLGNVVGSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAF---------GVPVKALCHSAN-QSLPAVPVPIK-----------------------------------------------------------------------PTPALP--TTLPPALAVPTASQQLPAP-------STVC-AAAASPTAPLLEPTAAGRADSKGGSLHSVLVHS-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYV0-1", "uniprot_id": "FOXB2_HUMAN", "id": "Q5VYV0-1", "name": "Forkhead box protein B2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPGKSS-------------------------------------------YSDQKPPYSYISLTAMAIQ------HSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRR------PDQPGKGSFWALHP---DCGDMFENGSFLRRR--------------------------------------------------------------------KRFKVLRADHTHLHAGSTKSAPGAGPGGHLHPHHHHHP-HHHHHHHAAAHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQS--------------------QPQQPSHPGKMQEAAAVAAAAAAAAAAAVGSV-------------------------------GRLSQFPPYGLGSAAAAAAAAAASTSGFKHPFAIENIIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLGNVVSSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAF---------GVPVKSLCHSAS-QSLPAMPVPIK-----------------------------------------------------------------------PTPALPPVSALQPGLTVPAASQQPPAP-------STVCSAAAASPVASLLEPTAPTSAESKGGSLHSVLVHS-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32028-1", "uniprot_id": "FD4_DROME", "id": "P32028-1", "name": "Fork head domain-containing protein FD4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPSRES-------------------------------------------YGEQKPPYSYISLTAMAIW------SSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVPRR------PDRPGKGAYWALHP---QAFDMFENGSLLRRR--------------------------------------------------------------------KRFKLHKNDKDLLNEELTALAN----------------------------------------------LNRFFFTTRNGGSAAHMSPLDMNNAAAMRLDPL--------------------PRSTAHMPNSL--GPGVPLPHVMPASMSGADH-------------------------------TNLADMGLTNLPALTSSEIEGPLSLR-PKRSFTIESLITPDKPEHPSEDEDDEDDRVDI----DVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGA---------HVPFLHYATGANVAGLPASGIPNS-----------------------------------------------------------------------PTTYELAISHPLFMMAAPIANMHN-------------IYYNNVTLVAPAQQYRSPEVQNRIDNDMRTI---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32029-1", "uniprot_id": "FD5_DROME", "id": "P32029-1", "name": "Fork head domain-containing protein FD5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRPLKMS-------------------------------------------YGDQKPPYSYISLTAMAII------HSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN------VTKAGKGSYWTLHP---MAFDMFENGSLLRRR--------------------------------------------------------------------KRFRVKQLEKDISNWKLAAAAN----------------------------------------------TEMVTHYLDD-----QLTQMAFADPARHGHVLA--------------------NASAAQMS------PYKATPPILPTTVT--------------------------------------------------------QLPAR-PKRAFTIESLMAPDPASTPNEG-----------------------------LVPMEYGSPDAVALEKPPFN---------------------------------LPFN------------------------------------------------------------------------------FNELAAQYQLYFPS---------------------FFYNGQYGNIPCYQKTPPLFHN---GPLPVF---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R2I0-1", "uniprot_id": "FOXE1_MOUSE", "id": "Q8R2I0-1", "name": "Forkhead box protein E1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAESAPPPPPQPETLAAVKEERGEAAAAGAGVPAEAAGRGAGGRRRKRP-------------------------------------------LQRGKPPYSYIALIAMAIA------HAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPRE------AGRPGKGNYWALDP---NAEDMFESGSFLRRR--------------------------------------------------------------------KRFKRSDLSTYPAYMHD----------------------------------------------------------AAAAAAAAAAAIFPGAVPAARPAYPGA-----------------------VYA--GYAPP-LAAPPPVYYPAASP-----------------------------------GPCRVFGLVPERPLSPDLGP-APSAAGGSC-AFAAAAGAAGTGS--FQPAVCTGAR------------PVNPAAYAAAYAGPDG-----AYPQGASSAL-------------------FAAAAGRLAGPASPPAGGGSGGVEA---------------------------------------------------------------------TVDFYGRTSPGQFGAALGPCYNPGG----------------QLGAGGGGAYHSRHATAYPGAVDRFVSAM-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00358-1", "uniprot_id": "FOXE1_HUMAN", "id": "O00358-1", "name": "Forkhead box protein E1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAESGPPPP-QPEVLATVKEERGE-TAAGAGVPGEATGRGAGGRRRKRP-------------------------------------------LQRGKPPYSYIALIAMAIA------HAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPRE------AGRPGKGNYWALDP---NAEDMFESGSFLRRR--------------------------------------------------------------------KRFKRSDLSTYPAYMHDAAAAA-----------------------------------------------------AAAAAAAAAAAIFPGAVPAARPPYPGA-----------------------VYA--GYAPPSLAAPPPVYYPAASP-----------------------------------GPCRVFGLVPERPLSPELGP-APSGPGGSC-AFASAGAPATTTG--YQPAGCTGAR------------PANPSAYAAAYAGPDG-----AYPQGAGSAI-------------------FAAAG-RLAGPASPPAGGSSGGVET---------------------------------------------------------------------TVDFYGRTSPGQFG-ALGACYNPGG----------------QLGGASAGAYHARHAAAYPGGIDRFVSAM-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6T0-1", "uniprot_id": "A0A8M2B6T0_DANRE", "id": "A0A8M2B6T0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVVKVESDSPSETTLPVNDSQRAEPQRGRRRKRP-------------------------------------------LQRGKPPYSYIALISMAIA------NSPDRKLTLGGIYKFITERFPFYRDNSKKWQNSIRHNLTLNDCFIKIPRE------PGRPGKGNYWALDP---NAEDMFESGSFLRRR--------------------------------------------------------------------KRFKRSDFTTYSSYVHE-------------------------------------------------------------------SPVFS-PVQIARSAYANS-----------------------VYSNMAVSPPYAQQLPSAYYQSSSPNFT-------------------------------AGQSRVFRINSLIGSPNRMGQNAEMIPQQSCRSFSPESGSCSLGGPGFQHQSCNGETVLSC-------YSSSSNNMAFAYSGPGHGQTQVSYPQ-ASTQH-------------------YGPAGRMAISSLSPIAGDAVG---------------------------------------------------------------------------DPYGRTSPAQLG--SFVQYNNSG----------------AVGSSGAYIRHP----AYSGNMDRFVSAT-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QY14-1", "uniprot_id": "FOXE3_MOUSE", "id": "Q9QY14-1", "name": "Forkhead box protein E3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAQVAFSGFPALPSLTPSGPQLPTLAGAEPGREPEEVVGG-GDAEPTAVPGPGKRRRRP-------------------------------------------LQRGKPPYSYIALIAMALA------HAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPRE------PGNPGKGNYWTLDP---AAADMFDNGSFLRRR--------------------------------------------------------------------KRFKRAELP---------------------------------------------------------------------------------APPPPPPPFPYA-----------------------PFP--PPP-----------APASAP------------------------------------PARLFRLDSLLGLQPEPPG--PVAPEPPCCAAPDAA---------FPPCAA----------------AASPPLYSPAS------------ERLGLPA-------------------------PLPAQPLLALAG-------------------------------------------------------------------------------------SAGALG---------------------------PLGAGEAYLRQP----GFAPGLERYL--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63250-1", "uniprot_id": "FOXE3_RAT", "id": "Q63250-1", "name": "Forkhead box protein E3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAHVAFSGFPTLPSVSPSGPQPPSLAGDEPGREPEEVVGG-GDSEPPAAPGPGRRRRRP-------------------------------------------LQRGKPPYSYIALIAMALA------HAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPRE------PGNPGKGNYWTLDP---AAADMFDNGSFLRRR--------------------------------------------------------------------KRFKRTELP---------------------------------------------------------------------------------APPPP--PFPYA-----------------------PFP--PAP-----------APAPAP------------------------------------PARLFRLDSLLGLQTEPPG--PLAPEPPCCAAPDAS---------FPPCAA----------------AASPPLYSPAP------------ERLGLPA-------------------------PLPAEPLLALAG-------------------------------------------------------------------------------------SAGALG---------------------------PLGAGEAYLRQP----GFPPGLERYL--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13461-1", "uniprot_id": "FOXE3_HUMAN", "id": "Q13461-1", "name": "Forkhead box protein E3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRP-------------------------------------------LQRGKPPYSYIALIAMALA------HAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPRE------PGNPGKGNYWTLDP---AAADMFDNGSFLRRR--------------------------------------------------------------------KRFKRAELPAH-----------------------------------------------------------------------------AAAAPGPPLPFPYA-----------------------PYA--PAPGPALLVPPPSAGPGPSP------------------------------------PARLFSVDSLVNLQPELAG--LGAPEPPCCAAPDAAAAA------FPPCAA----------------AASPPLYSQVP------------DRLVLPAT-------------------RPGPGPLPAEPLLALAG-------------------------------------------------------------------------------------PAAALG---------------------------PLSPGEAYLRQP----GFASGLERYL--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60688-1", "uniprot_id": "FOXD4_MOUSE", "id": "Q60688-1", "name": "Forkhead box protein D4", "aln": "------------------------------------------------------------------------------------------------------------------------------MNSARAGHLRSTPPPSPLSSDQDEVEIDVLAEEEDGDQTEEEDDEEESHKCLERSLQ------RPGARTLAGRSAGDCGDLSNSSGFLRKFRAPRTPATTTADG--------------------------------------PQPAKPPYSYIALITMAIL------QSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-HPPSGGHPHC-------------------------------------------------------------------PFPPPAVPATLHVSQPS------------------------LLLRYSAPPQPNLAAHPAAPPRSHPCAP-------------------------------LHPHPMRYLLLAAPAYGDNPRKAEGADPATPLAIPALQP----VLGSQP--WERDQSSGT---------RSGRGCASFTIESIMQGVTGGG---TGSAQ-------------------SPSFAPWSYCHLLQHPPCLLHPQAASPLFHMSAGSRTILPQQPQPPLPLQQEQ-------------------------------------HHCAISCAPGKGVRLGQHLSAVAALLRQ---------------------QPAADDGRLTTLAALSGREGTLPEF------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63249-1", "uniprot_id": "FOXD4_RAT", "id": "Q63249-1", "name": "Forkhead box protein D4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAKPPYSYIALITMAIL------QSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VB84-1", "uniprot_id": "FX4L3_HUMAN", "id": "Q6VB84-1", "name": "Forkhead box protein D4-like 3", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEA-ASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDA--------------------------------------RQPAKPPYSYIALITMAIL------QNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-QLTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPRPG------------------------PLLGAPAPPQPVPGAYPNTAPGRRPYAL-------------------------------LHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADAS--------LSALRVLCKGSGERVQGLRRICPRPRGATA-------------------TCSSDHQACCIPRPLPLCCK----------------------------------------------------------------------------CPPPP--LLGQFCSNSSSIRRR--------------------TAPTAALPPRARCWAGTCRPRRPC--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3SYB3-1", "uniprot_id": "FX4L6_HUMAN", "id": "Q3SYB3-1", "name": "Forkhead box protein D4-like 6", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEA-ASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDA--------------------------------------RQPAKPPYSYIALITMAIL------QNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-QLTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPHPG------------------------PLLGAPAPPQPVPGAYPNTAPGRRPYAL-------------------------------LHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADAS--------LSALRVLCKGSGERVQGLRRVCPRPRGATA-------------------TCSSDHQACCIPRPLPLCCK----------------------------------------------------------------------------CPPPP--LLGQFCSNSSSIRRR--------------------TAPTAALPPRARCWAGTCRPRRPC--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WXT5-1", "uniprot_id": "FX4L4_HUMAN", "id": "Q8WXT5-1", "name": "Forkhead box protein D4-like 4", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEE-ARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDA--------------------------------------RQPAKPPYSYIALITMAIL------QNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-QLTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPHPG------------------------PLLGAPAPPQPVPGAYPNTAPGRRPYAL-------------------------------LHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADAS--------LSALRVLCKGSGERVQGLRRVCPRPRGATA-------------------TCSSDHQACCIPKPLPLCCK----------------------------------------------------------------------------CPPPL--LLGQFCSNSSSIRR---------------------TAPTAALPPRARCWAGTCRPRRRC--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VV16-1", "uniprot_id": "FX4L5_HUMAN", "id": "Q5VV16-1", "name": "Forkhead box protein D4-like 5", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEE-ARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDA--------------------------------------RQPAKPPYSYIALITMAIL------QNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-QLTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPHPG------------------------PLLGAPAPPQPVPGAYPNTAPGRCPYAL-------------------------------LHPHPLRYLLLSAPVYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADAS--------LSALRVLCKGSGERVQGLRRVCPRPRGATA-------------------TCSSDHQACCIPKPLPLCCK----------------------------------------------------------------------------CPPPL--LLGQFCSNSSSIRR---------------------TAPTAALPPRARCWAGTCRPRRRC--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12950-1", "uniprot_id": "FOXD4_HUMAN", "id": "Q12950-1", "name": "Forkhead box protein D4", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEED----EDEEEA-ASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDA--------------------------------------RQPAKPPSSYIALITMAIL------QSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGRPGKGNYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFQRH-QPTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPRPG------------------------PLLGAPAPPQPVPGAYPNTGPGRRPYAL-------------------------------LHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADAS--------LSALRVSCKGSGERVQGLRRVCPRPRGATA-------------------PCSSDRQACRTILQQQQRHQEEDCAN---------------------------------------------------------------------GCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NU39-1", "uniprot_id": "FX4L1_HUMAN", "id": "Q9NU39-1", "name": "Forkhead box protein D4-like 1", "aln": "------------------------------------------------------------------------------------------------------------------------------MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEE-ASQKFLEQSLQPGLQVARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDA--------------------------------------RQPAKPPYSYIALITMAIL------QSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE------PGHPGKGTYWSLDP---ASQDMFDNGSFLRRR--------------------------------------------------------------------KRFKRH-QLTPGAHLPH-------------------------------------------------------------------PFPLPAAHAALHNPRPG------------------------PLLGAPALPQPVPGAYPNTAPGRRPYAL-------------------------------LHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQP----SLGPQP--WE-EGKGLAS--------PPGGGCISFSIESIMQGVRGAG---TGAAQ-------------------SLSPTAWSYCPLLQRPSSLSDN--------------------------------------------------------------------------FAATAAASGGGLRQRLRSHQGR--------------------GAGRAPVG-RVGAAAVSGGGRGL---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61345-1", "uniprot_id": "FOXD1_MOUSE", "id": "Q61345-1", "name": "Forkhead box protein D1", "aln": "------------------------------------------------------------------------------------------------------------------------------MTLS--TEMSDASG------LAEETDIDVVGEGEDDEEEEDDDDEGGGGRGGGGSRLPSSAQ-RRRRSYAGEDDLEDLEEE-DDDDLLLAS-RPAASPAPPGPAPAPGTGSGGC----SGAGAGG-GAGGGTGAGTGGG-AKNPLVKPPYSYIALITMAIL------QSPKKRLTLSEICEFISSRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE------PGNPGKGNYWTLDP---ESADMFDNGSFLRRR--------------------------------------------------------------------KRFKRQPLLAP-HAAAE-------------------------------------------------------------------ALLLRGAGPAAGAGDPG--AALFPPPPPPP--ACGYGAYGCAYGLQLPPCAPP-SALFAAAAAAAAAA--------------------------------FHPHSPPP--PPPPPPPPPGAAAELAR--TAFGY-RSHALAAALPGPLQAAAVKAGGPGAA----------ALARSPFSIESLIGRTRGPAAAGAHVSSGAASG------------TAPGPGGGGCAVQAAAGPAVALTR--------------------------------------------------------------------------SLVVAAAAAASSVSSSAALG---------------------TLHQGTALSSVENFTARISNC------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16676-1", "uniprot_id": "FOXD1_HUMAN", "id": "Q16676-1", "name": "Forkhead box protein D1", "aln": "------------------------------------------------------------------------------------------------------------------------------MTLS--TEMSDASG------LAEETDIDVVGEGEDEEDEEEEDDDEGGG-GGPRLAVPAQRR-RRRRSYAGEDELEDLEEEEDDDDILLAP-PAGGSPAPPGPAPAAGAGAG-------GGGGGG-GAGGGGSAGSG---AKNPLVKPPYSYIALITMAIL------QSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE------PGNPGKGNYWTLDP---ESADMFDNGSFLRRR--------------------------------------------------------------------KRFKRQPLLPPNAAAAE-------------------------------------------------------------------SLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPP-SALFAAAAAAAAAAA-------------------------------FHPHSPPP--PPPP----HGAAAELAR--TAFGY-RPHPLGAALPGPLPASAAKAGGPGAS----------ALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSGGGCAAQAAVGPAAALTR--------------------------------------------------------------------------SLVAAAAAAASSVSSSAALG---------------------TLHQGTALSSVENFTARISNC------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61060-1", "uniprot_id": "FOXD3_MOUSE", "id": "Q61060-1", "name": "Forkhead box protein D3", "aln": "------------------------------------------------------------------------------------------------------------------------------MTLSGSGSASDMSGQTVL--TAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPDLRLDEADEGPPVSAHHGQSQP---QALALPTEAT----GPGNDTGAPEADGCKG---GED----AVTGGGGPGAGSGATGGLTPNKPKNSLVKPPYSYIALITMAIL------QSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE------PGNPGKGNYWTLDP---QSEDMFDNGSFLRRR--------------------------------------------------------------------KRFKRHQQEHLREQTAL-------------------------------------------------------------------MMQSFGAYSLAAAAGAG------------------------PYGLHPAAAAGAYSHPAAAAAAAAAAAL-------------------------------QYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGS-QLGPSLQLQLNTLGAAAAAAGTAGAAGTTS-LIKSEPSARPSFSIENIIGA--GSAAPGGSAGGGGSGGGAG----------GGGGSGGGGGAQSFLRPPGTVQS--------------------------------------------------------------------------AALMATHQPLSLSRTTATIAPILS-----------------VPLSGQFLQPAASAAAAAAAAVQAKWPAQ----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJU5-1", "uniprot_id": "FOXD3_HUMAN", "id": "Q9UJU5-1", "name": "Forkhead box protein D3", "aln": "------------------------------------------------------------------------------------------------------------------------------MTLSGGGSASDMSGQTVL--TAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEE----GGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAIL------QSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE------PGNPGKGNYWTLDP---QSEDMFDNGSFLRRR--------------------------------------------------------------------KRFKRHQQEHLREQTAL-------------------------------------------------------------------MMQSFGAYSLAAAAGAAG-------------------PYGRPYGLHPAAAAGAYSHPAAAAAAAAAAAL-------------------------------QYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGS-QLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENIIGG--GPAAPGGSAVG---AGVAG----------GTGGSGGGSTAQSFLRPPGTVQS--------------------------------------------------------------------------AALMATHQPLSLSRTTATIAPILS-----------------VPLSGQFLQPAASAAAAAAAAAQAKWPAQ----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02361-1", "uniprot_id": "FD3_DROME", "id": "Q02361-1", "name": "Fork head domain-containing protein FD3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MHTSTDPMHTLHDSVSLSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGSGSSG-------------------------------------------GPLVKPPYSYIALITMAIL------QSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPRE------PGNPGKGNFWTLDP---LAEDMFDNGSFLRRR--------------------------------------------------------------------KRYKRAPTMQRFSFPAVFGTLS-----------------------------------------------------PFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGA-------------------------------DVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRDYAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDVESGNEQEDS----------------HISDSVDSACTNRLDAPPEALIFEAS-----------------------------------------------------------------------AEASDSSPRRRFDSEPLVLRTSKQ-----------------SSAKDFRIETLIGHHLHRGGSQEETSD------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q61574-1", "uniprot_id": "FOXS1_MOUSE", "id": "Q61574-1", "name": "Forkhead box protein S1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKQPSPESL---------------------------------------APSAEPTKPPYSYIALIAMAIQ------SSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRD------DRKPGKGSYWTLDP---DCHDMFQHGSFLRRR--------------------------------------------------------------------RRFTKRTGAQGTKGPVK-------------------------------------------------------IDHRPHRATSPDPGAPKTTTG-----RLCPFPQEVPNP---------------KGLSFEGLMGSLPANMSSTTSDVRPQ----------------------LPTGPKEMCSAKSGGPRE-----------LSEATSPSPCPAFGFSSAFSDAESLGKAPTPGVAPES-VG----------------------SSYQCRMQTLNFCMGTDPG----------------------LEHLLVSSVPTPGSSTPS--------------------------------------------------------------------------ASHRAPLPLPADSKEPWVAGSF----------------PVQGGSGYPLGLPP--CLYRTPGMFFFE---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43638-1", "uniprot_id": "FOXS1_HUMAN", "id": "O43638-1", "name": "Forkhead box protein S1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQQPLPGPG---------------------------------------APTTEPTKPPYSYIALIAMAIQ------SSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRD------DRKPGKGSYWTLDP---DCHDMFEHGSFLRRR--------------------------------------------------------------------RRFTRQTGAEGTRGPAK-------------------------------------------------------ARRGPLRATSQDPGVPNATTG-----RQCSFPPELPDP---------------KGLSFGGLVGAMPASMCPATTDGRPR----------------------PPMEPKEISTPKPACPGE-----------LPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIG----------------------SSYQCRLQALNFCMGADPG----------------------LEHLLASAAPSPAPPTPP--------------------------------------------------------------------------GSLRAPLPLPTDHKEPWVAGGF----------------PVQGGSGYPLGLTP--CLYRTPGMFFFE---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61572-1", "uniprot_id": "FOXC1_MOUSE", "id": "Q61572-1", "name": "Forkhead box protein C1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGSMARAYGPYTP--------------------------------------QPQPKDMVKPPYSYIALITMAIQ------NAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDAVKDKEEKGRLHLQEPPPPQA-------------------------------------GRQPAPAPPEQAEGSAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGG--------AGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QEASHHPASHQGRLTS---------------------WYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNS-----------PVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLL4-1", "uniprot_id": "A0ABK0LLL4_RAT", "id": "A0ABK0LLL4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTP--------------------------------------QPQPKDMVKPPYSYIALITMAIQ------NAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDAVKDKEEKGRLHLQEPPPPQA-------------------------------------GRQPAPAPPEQAEGSAPGPQQPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGHSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGG--------GGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QETSHHPASHQGRLTS---------------------WYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNS-----------PVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12948-1", "uniprot_id": "FOXC1_HUMAN", "id": "Q12948-1", "name": "Forkhead box protein C1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTP--------------------------------------QPQPKDMVKPPYSYIALITMAIQ------NAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDAVKDKEEKDRLHLKEPPPP---------------------------------------GRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAG------AAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGG--------AGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTS---------------------WYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNS-----------PVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DE25-1", "uniprot_id": "FXC1A_DANRE", "id": "Q9DE25-1", "name": "Forkhead box C1-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSSPNSLGVVPYISSDQSYYR---AAAGGGYTGMPAPMTMYSHAAH-DQYPASMARAYGPYTP--------------------------------------QPQPKDMVKPPYSYIALITMAIQ------NSPDKKVTLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDAMKDKEDRG---VKEAPSR-----------------------------------------QAQPQAREQEQ-SVPGSQ--PVRIQDIKTENGTS-TPPQAVSP-------TLSTVPKIESPDSSSS-MSSGS--PHSIPSTRSLSLDSAGEQHHQ----AP----AQGFSVDNIMTSLRGSPHS-----SGELTPSLVAPSRTGITPTLSLN-YSPNQSSVYSSPCSQNSISTTSN---------------------ATYHCNMQAMSLYAGGDRSGHLG-------------TTATTVDETLPDYSITTTTS----SLSHGNLS-----SAQEGHHP--HQGRLAS---------------------WYLNQAG-DIGHLG--------ATYPAQQQNFHSVREMFESQRIGLNNS-----------PVNGNNSCQMSFPPSQPIYRTSGAFVYDCSKF-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DE24-1", "uniprot_id": "FXC1B_DANRE", "id": "Q9DE24-1", "name": "Forkhead box C1-B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYPVSSQSPLGVVPYIPGDQGFYR---TATGGGYTGMPAPMSMYSHATH-EQYPGGMARAYGPYAP--------------------------------------AQQPKDMVKPPYSYIALITMAIQ------NSSDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDVLREKEDRDR------------------------------------------------------QGKDNPGQACEQDAQQPVKLRDIKTENGACTPPHDSTPP--------LSTVPKTESPDRSGGSACSGS------PQSQTP---------------------QQAFSMDTIMTGLRGSPQH----------AAELPASRAALPGSVSLTYSPTPQPAHYSPPCGQP----------------------------ATYHCNMQATSLYT-GDRG---------------------HGDDTLPEYTNTTNAS----SISHPHQS-----SSQESQHL--QQNRLAP---------------------WYLNQSG-ELGHLS--------ASYPGQQQNFHAVREMFETQRIALNSS-----------PVTGSNSCQMAFPSSQPLYRASGAFVYDCSKF-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61850-1", "uniprot_id": "FOXC2_MOUSE", "id": "Q61850-1", "name": "Forkhead box protein C2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSDPNALGVVPYLS-EQNYYR-----AAGSYGGMASPMGVYS--GHPEQYGAGMGRSYAPYHH-------------------------------------QPAAPKDLVKPPYSYIALITMAIQ------NAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDVPKDKEERAH-------------------------------------------------------LKEPPSTTAKGAPTGTPVADGPKEAEKKVVVKSEAASP-------ALPVITKVETLSPEGALQASPRSASSTPAGSPDGSLPEHHAAAPN---------GLPGFSVETIMT-LRTSPPGG---------DLSPAAARAGLVVPPLALPYAAAPPAAYTQPCAQGLEAAGS----------------------AGYQCSMRAMSLYTGAERPAHVCVP--------------PALDEALSDHPSGPGSPLGALNLAAGQEGALGASGHHHQHHGHLHPQAPPP--APQPPPAPQP---ATQATSWYLNHGG-DLSHLPG-------HTFATQQQTFPNVREMFNSHRLGLDNSS------LGESQVS-NASCQLPYRATPSLYRHAAPYSYDCTKY-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63246-1", "uniprot_id": "FOXC2_RAT", "id": "Q63246-1", "name": "Forkhead box protein C2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSDPNALGVVPYLS-EQNYYR-----AAGSYGGMASPMGVYS--GHPEQYGAGMGRSYAPYHH-------------------------------------QPAAPKDLVKPPYSYIALITMAIQ------NAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDVPKDKEERAH-------------------------------------------------------LKEPPPASAKGAPTGTPVADGPKEAEKKVVVKSEAASP-------ALPVITKVETLSPEGALQASPRSSASTPAGSPDGSLPEHHAAAPN---------GLPGFSVETIMT-LRTSPPGG---------DLSPAAARAGLVVPPLALPYAAAPPAAYAQPCAQGLEAAGS----------------------AGYQCSMRAMSLYTGAERPAHVCVP--------------PALDEALSDHPSGPGSPLGALNLAAGQEGALGASGHHHQHHSHLHPQAPPP--APQPPPAPQP---ATQATSWYLNHGG-DLSHLPG-------HTFATQQQTFPNVREMFNSHRLGLDNST------LGESQVS-NASCQLPYRATPSLYRHAAPYSYDCTKY-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99958-1", "uniprot_id": "FOXC2_HUMAN", "id": "Q99958-1", "name": "Forkhead box protein C2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MQARYSVSDPNALGVVPYLS-EQNYYR-----AAGSYGGMASPMGVYS--GHPEQYSAGMGRSYAPYHHH------------------------------------QPAAPKDLVKPPYSYIALITMAIQ------NAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD------DKKPGKGSYWTLDP---DSYNMFENGSFLRRR--------------------------------------------------------------------RRFKKKDVSKEKEERAH-------------------------------------------------------LKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASP-------ALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPN---------GLPGFSVENIMT-LRTSPPGG---------ELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAA----------------------GGYQCSMRAMSLYTGAERPAHMCVP--------------PALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSG-DLNHLPG-------HTFAAQQQTFPNVREMFNSHRLGIENST------LGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64731-1", "uniprot_id": "FOXL1_MOUSE", "id": "Q64731-1", "name": "Forkhead box protein L1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSHLFSPP----------------------------LAALAASPLLYVYSPERPGLPLAFAPAAALAGP---------------------------------------GRVEPPQKPPYSYIALIAMAIQ------DAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPRE------KGRPGKGSYWTLDP---RCLDMFENGNYRRRK--------------------------------------------------------------------RKPKP-------------------------------------------------------------------------------------AAGSPEAKRTRVEPPE------------------SEVGCDVGSPDLATALPTRAPDRSQSP-----------------------------AVGTARPALLPWPGPEPRDPDADLTVQG---------AGAVASGQLQRPAHHLGSPLCPAPS----------------------GSPKGS-KSKSFSIDSILAVR---------------------PTPASGAE--------------------------------------------------------------------------------APGIPKPVPG-ALGSSLLAASSGLAPPFNAS------LVFDAHVQGGFSQLG-IPFLSYFPLQVPEATVLRFH-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12952-1", "uniprot_id": "FOXL1_HUMAN", "id": "Q12952-1", "name": "Forkhead box protein L1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSHLFDPR----------------------------LPALAASPMLYLYGPERPGLPLAFAPAAALAAS---------------------------------------GRAETPQKPPYSYIALIAMAIQ------DAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE------KGRPGKGSYWTLDP---RCLDMFENGNYRRRK--------------------------------------------------------------------RKPKP-------------------------------------------------------------------------------------GPGAPEAKRPRAETHQRSAE------------AQPEAGSGAGGSGPAISRLQAAPAGPSPL-----------------------------LDGPSPPAPLHWPGTASPNEDAGDAAQG---------AAAVAVGQAARTGDGPGSPLRPASR----------------------SSPKSSDKSKSFSIDSILAGKQG-------------------QKPPSGDE--------------------------------------------------------------------------------LLGGAKPGPGGRLGASLLAASSSLRPPFNAS------LMLDPHVQGGFYQLG-IPFLSYFPLQVPD-TVLHFQ-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32027-1", "uniprot_id": "CROC_DROME", "id": "P32027-1", "name": "Fork head domain-containing protein crocodile", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MHTLFSDQNSFTRHYAQTAAGYGSASA-------VAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAP---------------------------------------HQNKEIVKPPYSYIALIAMAIQ------NAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARD------DKKPGKGSYWTLDP---DSYNMFDNGSFLRRR--------------------------------------------------------------------RRFKKKDVMREKEEAIK-------------------------------------------------------RQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKE------------PLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGGGVEHP------------GFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQ----------------------GAGGQSSGHSPTTISTPHGPAHGGWYTP--------ETPPSEPVPHNGQQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRD----------MIFEQNQSCQLDTGSPTGSLQSASPPASASVAAASAAAAAAVISSHHHH------HHHHAALSGNLGQLGQLSNLSHYRPHVGHYQEYGIKYGV--------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3I5G5-1", "uniprot_id": "FOXI2_MOUSE", "id": "Q3I5G5-1", "name": "Forkhead box protein I2", "aln": "--------------------------------------------------------------------------------------------------------------------MAGFC-DSLGSCSVPHG--------LTRAIAHPPS----YGRTDLSS------GRRLWVNSA---------ALSPAPYATGPGPAPSYAAAT------LAVPGSLLGASGGLAG------------------------ADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQ------SAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRD------ENDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------RRRGETS--EAAVPGAS-------------------------------------------------------------------------SP---EGTALE---------------------------------------PRGSTPQDPQ------------------------------------------------------TSPSPSE-ATTTCLSGFSTAMGALAGG-------------------------------------FG----------------------------------ALPDGLAHDFSLRRPPPTAA----------------------------------------------------------------------------AHSPQIPNTA--PGFAPGHQTG----------------ATG-----FRMG-HLIYSRDGTEV----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZQN5-1", "uniprot_id": "FOXI2_HUMAN", "id": "Q6ZQN5-1", "name": "Forkhead box protein I2", "aln": "--------------------------------------------------------------------------------------------------------------------MATYC-DDLGPSSAPPG--------QAQATAHPPG----YEPGDLGAV---GGGPLLWVNAP---------ALSPKSYASGPGPAPPYAAPS------YGAPGPLLGAPGGLAG------------------------ADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQ------SAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRRAEAS--AAVRSGAR-------------------------------------------------------------------------SVGGAEAPALE---------------------------------------PPSAACLDLQ------------------------------------------------------ASPSPSAPEAATCFSGFASAMSALAGG-------------------------------------LG----------------------------------TFPGGLAGDFSFGRRPPTVA----------------------------------------------------------------------------THAPQTLNPS--PGFAPGHQTA----------------AAG-----FRLS-HLLYSREGTEV----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63248-1", "uniprot_id": "FOXI2_RAT", "id": "Q63248-1", "name": "Forkhead box protein I2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVRPPYSYSALIAMAIQ------SAPRRRLTLSQIYQYVAGNFPFYKRTKAGWQNSIRHNLSLNDCFKKVPRD------ENDPGKGNYWMLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------RRRGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z120-1", "uniprot_id": "FOXI3_MOUSE", "id": "D3Z120-1", "name": "Forkhead box protein I3", "aln": "--------------------------------------------------------------------------------------------------------------------MALYCGDNF-VYSQP-----------AAAPGAPPTSRAPYGLSDYAAPPAAAANPYLWLNGPGVGGP-----ASAASYLGAPPPPP--GAAPGPFLQPPAAPGTFAGAQRGFAQPSASA---------PASPAGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQ------SAPERKLTLSHIYQFVADNFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------RRRAEASSNLTVPSGTS-------------------------------------------------------------------------KSE-GQSSRLR-------------------------VSGKLEGDSPSSILRPSQSPEPPEGTK------------------------------------------------STASSPGASTLTSTPCLNTFLSTFNTLNVNSSSSMGNQRTLP--------------------GSRRHLG--GTQLPSS-TFPNT-------------------SVPDSSPDSMQLS--TVGGS----------------------------------------------------------------------------NQLSSYYNPF--SGGSSGDQSS----------------PFSSPFYNFSMVNSLIYPRDGSDI----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLN2-1", "uniprot_id": "D3ZLN2_RAT", "id": "D3ZLN2-1", "name": "", "aln": "------------------------------------------------------------------------------------------MLSPKRRGQPLSPKAAAAPHQPSASDMALYCGDNF-VYSQPAA---------AAAPGAPPTSRAPYGLSDYAAPPAAAANPYLWLNGPGVGGP-----ASAAGYLGAPPPPP--GAAPGAFLQPPAAPGTFAGAQRGFTQPSAAA---------PASPAGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQ------SAPERKLTLSHIYQFVADNFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------RRRAEASSNLTVPSGTS-------------------------------------------------------------------------KSD-GQSSRLR-------------------------VSGKLEGDSPSSMLRPSQSPEPPEGTK------------------------------------------------STASSPGASTLTSTPCLNTFLSSFNTLSVN-ASSMSTQRTLP--------------------GSRRHPG--GTQLPSSTTFPST-------------------SIPDSSLDSVQLS--TVGGG----------------------------------------------------------------------------SQLSSYYSPF--SGGS-GDQSS----------------PFGSPFYNFSMVNSLIYPRDGSDM----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MTJ6-1", "uniprot_id": "FOXI3_HUMAN", "id": "A8MTJ6-1", "name": "Forkhead box protein I3", "aln": "--------------------------------------------------------------------------------------------------------------------MALYCGDNFGVYSQPGLPP---PAATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAA---------PASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQ------SAPERKLTLSHIYQFVADSFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRRSEASNGSTVAAGTS-------------------------------------------------------------------------KSEEGLSSGLGS-----------------------GVGGKPEEESPSTLLRPSHSPEPPEGTK------------------------------------------------STASSPGGPMLTSTPCLNTFFSSLSSLSVS--SSVSTQRALP--------------------GSR-HLGIQGAQLPSSGVFSPT-------------------SISEASADTLQLSNSTSNST----------------------------------------------------------------------------GQRSSYYSPF--PASTSGGQSS----------------PFSSPFHNFSMVNSLIYPREGSEV----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNJ3-1", "uniprot_id": "FXI3A_DANRE", "id": "A3KNJ3-1", "name": "Forkhead box protein I3-A", "aln": "-----------------------------------------------------------------------------------------------------------MTSFVPQSLS-----PQFHSMGQESQEFSLYGDNFYSAQHVPSPQQTLPSAYDFGEYAGQTSNPYLWFNGPG---------LSPAPCL--TTG------------------PQHYGMAKQYVGASGI----------------GGSEGAFSWFSLPSQEDLMKLVRPPYSYSALIAMAIH------GAPNRRLTLSQIYQYVADNFPFYNKSKASWQNSIRHNLSLNDCFMKVPRD------DSDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRKSDSLAEEEGKG--Y-------------------------------------------------------------------------SGSDSALSSPK----------------------------NP--------------SDSSE------------------------------------------------------RGNSPISTDQAPCLNSFLNQMGDVASG------SRE-------------------------ALLPSPLAVPLS--QRSSPT-------------------GVYGSYSPNATMPQWETQIP----------------------------------------------------------------------------QSS-ISSTPYKD--GYSDSMLN----------------PYSSQLYPVLGSSDLLYPREGSEV----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T1C0-1", "uniprot_id": "FXI3B_DANRE", "id": "Q7T1C0-1", "name": "Forkhead box protein I3-B", "aln": "-----------------------------------------------------------------------------------------------------------MTSYESQGQSPTRCGPQFLSLGQEPPELSLYSDSYYPPPSLPSPQRTNPSSYELGDYAASSPNPYLWFNSPG---------MNSAPYLGGTPGPAG-----------PSFVPQHYGMQRPYLGPGPP----------------GGPGGELSWFSMPSQEDLMKLVRPPYSYSALIAMAIH------GAPERRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRKSDSLPEKSSSGGNE-------------------------------------------------------------------------SGDSNGRGSPK----------------------------SQSID----------ISTSPE------------------------------------------------------KGPSPASTGPSPCLSNFLTEMSGVAAG------SLDMEA--------------------DPLSRPFTLSLPVDGAQRASQT-------------------TGFSTFTPSTTVSDWASPLP----------------------------------------------------------------------------PPPPMSSSPSHSTLAYSGPVLS----------------QFNGHFFPGLSSTGILYPREGTEV----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q922I5-1", "uniprot_id": "FOXI1_MOUSE", "id": "Q922I5-1", "name": "Forkhead box protein I1", "aln": "-----------------------------------------------------------------------------------------------------------MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGMPSPQRPT--SFEGGGEYGTTPNPYLWLNGPA---------MTPPPYLPGTNASP--------------FLPQAYGMQRQLLP------------------------SDLGWLPIPSQEELMKLVRPPYSYSALIAMAIH------GAPDQRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRKSDSSSSTSSLASEK-------------------------------------------------------------------------TENGLLASSPK----------------------------PTEPQEVLDTASPDTTTSSPE------------------------------------------------------KRSSPAPSG-TPCLNNFLSTMTAYVSG------TNPIS---------------------RSVATPGLSSEPIDKMGQNSLN---------------------FNSYTPLTNLSSHGNGGE----------------------------------------------------------------------------WANPVATN----ALGYGGSVFN----------------QFSPHFYNSINTNGILFPREGTEV----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7G2-1", "uniprot_id": "D4A7G2_RAT", "id": "D4A7G2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGMPSPQRPT--SFEGGGEYGATPNPYLWLNGTA---------MTPPPYLPGTNASP--------------FLPQAYGMQRQLLP------------------------SELGWLPIPSQEELMKLVRPPYSYSALIAMAIH------GAPDQRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRKSDASSSTGSLASEK-------------------------------------------------------------------------TENRLLSSSPK----------------------------PTEPQEVLDTASPDTTSSSPE------------------------------------------------------KRSSPAPSG-TPCLNNFLSTMTAYVNG------TNPIS---------------------RSAATPGLSPEPVDKMGQNSLN---------------------FNSYTPLTNLSSHGNGGE----------------------------------------------------------------------------WANPVPTN----ALGYGGPVFN----------------QFSPHFYNSINTNSILFPREGTEV----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12951-1", "uniprot_id": "FOXI1_HUMAN", "id": "Q12951-1", "name": "Forkhead box protein I1", "aln": "-----------------------------------------------------------------------------------------------------------MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRP---SFEGGGEYGATPNPYLWFNGPT---------MTPPPYLPGPNASP--------------FLPQAYGVQRPLLPSVS-----------------GLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIH------GAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD------EDDPGKGNYWTLDP---NCEKMFDNGNFRRKR--------------------------------------------------------------------KRKSDVSSSTASLALEK-------------------------------------------------------------------------TESSLPVDSPK----------------------------TTEPQDILDGASPGGTTSSPE------------------------------------------------------KRPSPPPSG-APCLNSFLSSMTAYVSG------GSPTS---------------------HPLVTPGLSPEPSDKTGQNSLT---------------------FNSFSPLTNLSNHSGGGD----------------------------------------------------------------------------WANPMPTN----MLSYGGSVLS----------------QFSPHFYNSVNTSGVLYPREGTEV----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70220-1", "uniprot_id": "FOXQ1_MOUSE", "id": "O70220-1", "name": "Forkhead box protein Q1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQAS---------AAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIR------DSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRD-----PSRPWGKDNYWMLNP---NSEYTFADGVFRRRR--------------------------------------------------------------------KRLSHRTTVSASGLRPEEAPP----------------------------------------------------------GPAGTPQPAPAARSSPIARSPARQEERSS------------------PASKFSSSFAIDSILSKPFRSRRD---------------------------------------------GDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASE---------------------------------------PTLLASR------------------GTEVQPAAP-LLLAPLSTAAP--------------------------------------------------------------------------AKPFRGPETAGAAHLYCPLRLPT-----------------ALQAAAACGPGPHLSYPVETLLA-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63244-1", "uniprot_id": "FOXQ1_RAT", "id": "Q63244-1", "name": "Forkhead box protein Q1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MKLEVFAPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGASTQDDPEVTDGSRTQAS---------PVGPCAGSVGGGEGARSKPYTRRPKPPYSYIALIAMAIR------DSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRD-----PSRPWGKDNYWMLNP---NSEYTFADGVFRRRR--------------------------------------------------------------------KRLSHRTTVSASGYG-GGSPP----------------------------------------------------------GPAGTPQPAPTAGSSPIARSPARQEEGSS------------------PASKFSSSFAIDSILSKPFRSRRD---------------------------------------------GTPALGVQLPWSAAPCPPLRAYPALLPASSGGALLPLCAYGAAE---------------------------------------PTLLASR------------------GAEVQPAAP-LFVAPLSTAAP--------------------------------------------------------------------------AKPFRGPETAGAAHLYCPLRLPT-----------------ALQAAAACGPGPHLSYRVETLLA-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C009-1", "uniprot_id": "FOXQ1_HUMAN", "id": "Q9C009-1", "name": "Forkhead box protein Q1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDG-EQSAGGGPGAEEAIPAAAAAAVVAEG----AEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIR------DSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRD-----PSRPWGKDNYWMLNP---NSEYTFADGVFRRRR--------------------------------------------------------------------KRLSHRAPVPAPGLRPEEAP-----------------------------------------------------------GLPAAPPPAPAAPASPRMRSPARQEERAS------------------PAGKFSSSFAIDSILRKPFRSRRL---------------------------------------------RDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGE---------------------------------------PARLGAR------------------EAEVPPTAPPLLLAPLPAAAP--------------------------------------------------------------------------AKPLRGP-AAGGAHLYCPLRLPA-----------------ALQAASVRRPGPHLPYPVETLLA-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1U091-1", "uniprot_id": "A0A8N1U091_DANRE", "id": "A0A8N1U091-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MKLEVFS--ASRLVDKPLDLCSDMDVNVASPLST--EEELGSDGDCSANSPGPGAPVPD------------------------------------------------------GKAKPYTRRPKPPYSYIALIAMAIR------DSNTGRLTLAEINEYLMKKFPFFRGSYTGWRNSVRHNLSLNDCFLKVLRD-----PSRPWGKDNYWMLNP---HSEYTFADGVFRRRR--------------------------------------------------------------------KRISKKILGSAE-----------------------------------------------------------------------SPERVPADDS----RLPARDE----------------------SVSKFSSSFAIDSILSKPFMRREQST-------------------------------------------DDTCFGTTR-------LMLSAAPHFLPVAMG--------YPPQS---------------------------------------RFQVSSE------------------VSNVFPIYR-CNTADISNISR--------------------------------------------------------------------------MADIQSS-LPGLAHSHT-----------------------TLQEAGFH------PFRIDSLLS-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I9E1-1", "uniprot_id": "FOXH1_DANRE", "id": "Q9I9E1-1", "name": "Forkhead box protein H1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MTKHWGGPGLLAPPVITVGEGAQRDHHLDCRIGYSSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATNQ-----------------------GPWELQDGNSSGGKKKNYQRYPKPPYSYLAMIAMVIQ------NSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKD-----PGKPQGKGNFWTVEV---N---RIPLELLKRQN--------------------------------------------------------------------TAVSRQDETIFAQDLAPYIFQ----------------------------------------------------------GYSQPNKSKPLPPESSLPPVPTRQSPPPSED---------------PYRPKLDSTFAIDSLLHSLRPASSAGEG----------------------------------------LRERESWGVGPPPHTRSTTPPRPCNASYNGSSSASSVSPASDFSDEDWRGVTVVGKRSGDRGITSDAYSDSCPPPNKSSKRGNTPPWELPTS------------------YAKYTPPNAVAPPSMRFNGNP--------------------------------------------------------------------------FMPLGGIPFYGYGGAHVTTSHLIGHPY-----------WPILPSGPVSIQAPPLLMDLDSMLQSVPPNKSVFDALGSNNQTVHPSPNQYALQNGPSLCKYSL--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QDF8-1", "uniprot_id": "FXJ1A_DANRE", "id": "F1QDF8-1", "name": "Forkhead box protein J1-A", "aln": "-------------------------------------------------------------------------------------------------------MLSMSSMDPWPEGSVGLEEEVVTAAAQAERLDTSTPLQCNTSLDSDNLDDSLTSLQWLQEFSILNASTG----QHTSPS----SHSHLMGSDAPSSPLAGDPASIGMPLTPGKPTAASFCRVPMFSALPS--------------------LVAHGHCPDEVDYKSNPHIKPPYSYATLICMAMQ------ASKKTKITLSCIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPRQ------KDEPGKGGFWKIDP---QYAERLLNGAYKKRR-----------------------------------------------------------------LPPVQINPA-LQHRLRMNAQATGVI------------------------------------------------------------SRNLSVSPESQQLLKDFEEATSADQNWDPRLAEATMLSCWISGKG--TNKRKQPYNHRTGKTPRRSSSPLLV--------------------------------MDEQEDLSSLRGNFDWDALLDS-ALNGELSLNEG----SPLSP---TPQ-DEELMIRGT------------------HISPQEAPVENHVLMETQRSGD--------------------EDFDEETFLATAFLQSP---------------------------------------------------------------------------WSEVDESNRSDFLGSSTVSIDQLFD----------------LSFG------GDLS--SKIETLL-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63247-1", "uniprot_id": "FOXJ1_RAT", "id": "Q63247-1", "name": "Forkhead box protein J1", "aln": "--------------------------------------------------------------------------------------------------------MAESWLRLCG---AGPGEEAGPEGGMEE---------------PDALDDSLTSLQWLQEFSILNAKAPTLPPGGTDPL----GYHQVPGLVAPGSPLAADPACLGQPHTPGKPTSSCTSR----SAPPG--------------------LQAP--PPDDVDYATNPHVKPPYSYATLICMAMQ------ASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPRE------KDEPGKGGFWRIDP---QYAERLLSGAFKKRR-----------------------------------------------------------------LPPVHIHPA-FARQAAQ-EPSTAPW------------------------------------------------------------GGPLTVNREAQQLLQEFEEATGEGG--------------WGTGEGRLGHKRKQPLPKRVAKVLRPPSTLLLT--------------------------------QEEQGELEPLKGNFDWEAIFEAGALGEELSSLEGLELSPPLSP---SSHGEVDLTVHGR------------------HIN---CPATWGPPVE-QATDS--------------------LDFD-ETFLATSFLQHP---------------------------------------------------------------------------WDESS----SGCLPPE--PLFEAGD----------------ATLA------ADLQDWASVGAFL-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1R8Z9-1", "uniprot_id": "FXJ1B_DANRE", "id": "F1R8Z9-1", "name": "Forkhead box protein J1-B", "aln": "----------------------------------------------------------------------------------------------------MPVLMSPEIANKFKEKWLMLHPED--QDNVSG---------------SVHFDDSLTSLHWLQNFSILSANPERTPSSGCHPQHLFYYKNQLGGTDSPSSPPAGDTAATGMPQTPGNPTTSCSSLANPYALQQAGH-----------------YITGQTNPAEEIDYKTNRHVKPPYSYATLICMAMQ------ASNKTKITLSAIYSWITENFCYYRYAEPSWQNSIRHNLSLNKCFMKVPRQ------KDEPGKGGFWQIDP---QYADMFVNGVFKRRR-----------------------------------------------------------------MPATNFN---TQRQSKMLSSPS----------------------------------------------------------------SSYTSQCNQQMGMGHFQ-----------------------------GNKRKQVFPKRGNKLARISKSPLLT--------------------------------SDIK-TSDVLRGDFDLASVFDD-VLSGNDSTFEDLDINTALSSLGCEMEPSSQIHNQSG------------------YSNEDEQACAYLEANGIIGCNM--------------------EDFHHQQHHQQAQVHPQYY----------------------------------------------------------------------EGMFSDQQNQQHPWEIKEEAQPVPLSLD----------------HGYAFCEGFFSEMQLWERGESYM-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UPW0-1", "uniprot_id": "FOXJ3_HUMAN", "id": "Q9UPW0-1", "name": "Forkhead box protein J3", "aln": "---------------------------------------------------------------------------------------------------------------------MGLYGQACPSVTSLR--------------MTSELESSLTSMDWLPQLTMR---------------------AAIQKSDATQNAHGTGISKKNALLDPN-------------------------------------------TTLDQEEVQQHKDGKPPYSYASLITFAIN------SSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRS------KDDPGKGSYWAIDT---NPKEDVLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESV------------------------------------------------------------SQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHS--------------------------------PSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQ------------------HPQRSPHPAPHPQQHSQLQSPH--------------------PQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLK--------------------------------ESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWS----------------LDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQN-LPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AQ64-1", "uniprot_id": "A0A8I6AQ64_RAT", "id": "A0A8I6AQ64-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------MGLYGQACPSVTSLR--------------MTSELESSLTSMDWLPQLTMR---------------------AAIQKSDATQNAHGTGISKKNALLDPN-------------------------------------------TTLDQEEVQQHKDGKPPYSYASLITFAIN------SSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRS------KDDPGKGSYWAIDT---NPKEDTLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPV------------------------------------------------------------SQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHS--------------------------------PSSTVTSHPHSNQSSLPNNH-SGLSATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQ------------------HPQRPQHPASHPQQHSQLQPPH--------------------SQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLK--------------------------------ESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWS----------------LDQVQFADLCSSLNQFFTQTGLIHSQSNAQQNVCHGAMHPAKPSQHIGAGNLYIDSRQSGIPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UCQ1-1", "uniprot_id": "FOXK2_MOUSE", "id": "Q3UCQ1-1", "name": "Forkhead box protein K2", "aln": "-MAAAAALSGAGAPPAGG-----GAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGG-HSAAAPEP--AQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQ---------------PENEKEASGGDSPKDDSKPPYSYAQLIVQAIT------MAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDP---ASESKLVEQAFRKRRPR----------------------------------------------------------------GVPCFRTPLGPLSSRSAPASPNHAG--------------------------------------------------------VLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTP---------------------TSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLG-----------QHQLPIKTVTQNGAHVVPMPTAVHS--------------------------------------------------------------------------QVNNAAASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01167-1", "uniprot_id": "FOXK2_HUMAN", "id": "Q01167-1", "name": "Forkhead box protein K2", "aln": "MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQ---------------PENEKEASGGDSPKDDSKPPYSYAQLIVQAIT------MAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDP---ASESKLIEQAFRKRRPR----------------------------------------------------------------GVPCFRTPLGPLSSRSAPASPNHAG--------------------------------------------------------VLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTS---------------------TSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLG-----------QHQLPIKTVTQNGTHVASVPTAVHG--------------------------------------------------------------------------QVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "----------------------------------------------------------------------------------------MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVN-------------------------------------FRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRL------QEEARLQQLDHLHTPLSSSSDVNPIGDPHGDT--------------------------------------------------------------------IMMEEDEEDENYTRGGIRPN----------------------------------------------------------------TYTSSSNNAVTNGNVPHIENPS---------------DLSLDENRYIKPPQSYASMITQAILSTPEGSIS--------------------------------LADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVR-----------------RDFLNKWNAGKLSKIRRGASVTR-------------------QLQLHMSKFGEIPAPESSSID------------------------------------------------------------------------PRGIKAQKVKKSLQATSSILGESAP--------------QLQRTQLTGQISTTTSMDVTTNANVNNSSLS-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .:.: :.: : : : . ", "identical_positions": 0, "similar_positions": 14, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000001395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19253-1", "uniprot_id": "RL13A_MOUSE", "id": "P19253-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKMHYRKKKQILRLRKQAEKNVEKKICKFTEVLKTNGLLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35427-1", "uniprot_id": "RL13A_RAT", "id": "P35427-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EGQVLVLDGRSHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40429-1", "uniprot_id": "RL13A_HUMAN", "id": "P40429-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNE9-1", "uniprot_id": "RL13A_DROME", "id": "Q9VNE9-1", "name": "Large ribosomal subunit protein uL13", "aln": "MTGLTNRTVVIDGRGHLLGRLASVVAKYLLQGGKVAVVRCEELNLSGHFYRNKIKFLAYLRKRCNVNPARGPFHFRAPSRIFYKAVRGMIPHKTKRGQAALARLRVFDGIPSPYDKRRRVVVPIAMRVLTLRSDRKYCQVGRLSHEVGWHYQDVIKSLERKRKAKLRVTLKHNRELKKLTVKARENIAKAAEPFNKIIKSYGYEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26784-1", "uniprot_id": "RL16A_YEAST", "id": "P26784-1", "name": "Large ribosomal subunit protein uL13A", "aln": "MS--VEPVVVIDGKGHLVGRLASVVAKQLLNGQKIVVVRAEELNISGEFFRNKLKYHDFLRKATAFNKTRGPFHFRAPSRIFYKALRGMVSHKTARGKAALERLKVFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEAKRKVSSAEYYAKKRAFT--KKVASANATAAESDVAKQLAALGY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:*:**:.**:****::*** :* * *:.***.* :*:**.*:***:*: :*** * :***:*********::::***:.*** **:*** **:*::***.****::*:*** *::*: *:. **: :*:*: .***:*: * .** *** . ::: : * * : : : * ", "identical_positions": 89, "similar_positions": 57, "identity": "43.41%" }, { "cls_id": "homologset.agr.SGD:S000001396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMG8-1", "uniprot_id": "S2532_MOUSE", "id": "Q8BMG8-1", "name": "Solute carrier family 25 member 32", "aln": "MTGQGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDG-LEVRPKYKGILHCLATIWKVDGLRG------LYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEG-------------RAEQLEPLEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLK-LKYNKHINRLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYG--GVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLYDLR-------------EKKVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y115-1", "uniprot_id": "A0A8I5Y115_RAT", "id": "A0A8I5Y115-1", "name": "Solute carrier family 25 member 32", "aln": "MTSQGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDG-LEVRPKYKGILHCLATIWKVDGLRG------LYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEG-------------RAEQLEALEYLISAAEAGAMTLCITNPLWVTKTRLMLQYGGVVNPSQRQYKGMIDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEVLK-LKYNKHINKLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYG--GVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENCMCLKQQQTPLCLKHKARKSPAEQHSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2D1-1", "uniprot_id": "S2532_HUMAN", "id": "Q9H2D1-1", "name": "Solute carrier family 25 member 32", "aln": "MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDG-LELRPKYNGILHCLTTIWKLDGLRG------LYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEG-------------RAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLK-LKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYS--GVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLR-------------EKRK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7S4-1", "uniprot_id": "A1Z7S4_DROME", "id": "A1Z7S4-1", "name": "Mitochondrial folate transporter/carrier", "aln": "MNPIKAQSTGSPKKFNVFAHVKYEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTTIFRQEGFRG------LYKGVTPNVWGSGSSWGLYFMFYNTIKTFIQGGN------------TTMPLGPTMNMLAAAESGILTLLLTNPIWVVKTRLCLQCDAASS---AEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGVSHGAIQFMTYEELK-NAYNEYRKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHHHRYN--GTWDCIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYENVSHFLLARR-------KRIETKEDASDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40464-1", "uniprot_id": "FLX1_YEAST", "id": "P40464-1", "name": "Mitochondrial FAD carrier protein FLX1", "aln": "-------------MVDHQWTPLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSAT--SAQKAHYGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLMTAILTNPIWVIKTRIMSTSKGAQG----AYTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTLKQRKLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENLKHRL-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:::*:*.* ::.* :*****:*:*: :. : * : * : .. * **:*:: *::* . :**:** :*.. * . : . : :.*.:* :* :***:** ***: .. . * .* . : :: : :*.:**::*:**.::*.*:**: * .*: ** .. : : :*:. * : .:::.*:.:.: .**:*::::.**. : *. :* *:***: ..* *. *: :** **** ", "identical_positions": 75, "similar_positions": 103, "identity": "21.25%" }, { "cls_id": "homologset.agr.SGD:S000001399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ22-1", "uniprot_id": "ERAP1_RAT", "id": "Q9JJ22-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "-----------------------MPSLLSLVLTFLAVSSPSCCQNSD---------------------------TASPKASNGASFPWNNMRLPEYITPIHYDLMIHANLSTLT-----FWGKTEVEITVSQPTSTIIMHSHQLQIS------KATLRRGAEEMLPEEPLKLMEYS-AHEQVALLTAQPLLAG-SVYTVIITYAANLS------ENFHGFYKSTYRTQEGER--RILAATQFEPTAARMAFPCFDEPALKASFSIKIKRD-PRHLAISNMPLVK---SVTVAEGLIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSG-----VKVSVYAVPDKIN--QADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLYDK-EKSSASSKLGITMTVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVT---VTHPELKVEEYFFGKCFN-AMEVDALNSSHPVST----PVENPAQIREMFDEVSYEKGACILNMLRDYLSADTFKRGIVQYLQK---YSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRNQHSSSTSHWRQEVIDIKSMMNTWTLQKGFPLITITVRGR-------NVHLKQEHYMKGSECFPETGSLWHVPLTFITSKSDSVQRFLLKTKTDVIIL---------------PEAVEWIKFNVGMNGYYIVHYGDDGWASLNGLLKE--AHTTISS----NDRASLINNAFQLVSIGKLSIEKALDLILYLKNETEIMPIFQGLNELIPMYKLMEKRDMVEVETQFKDFLLRLLKDLINKQT-----WTDEGS-VSERMLRSQLLLLACVHRYQLCVQRAERYFREWK---ASNGNMSLPIDVTLAVFAVGAQNTEG---WDFLYSKYQSSLSSTEKSQIEFSLCISQDPEKLQWLLDQSF-KGEIIKTQEFPHILTLIGRNPVGYPLAWKFLKENWNKIVQKFELGSSSIAHMVMGTTNQFSTRARLEEVKGFFSSLKKN-------------------GSQLRCVQQTIETIEENIRWMDKNFDKIRLWLQKERQELL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQH2-1", "uniprot_id": "ERAP1_MOUSE", "id": "Q9EQH2-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "-----------------------MPSLLPLVLTFLSVSSPSWCQNSD---------------------------IESLKASNGDSFPWNNMRLPEYMTPIHYDLMIHANLSTLT-----FWGKTEVEIIASRPTSTIIMHSHHLQIS------KATLRRGAGEMLSEEPLKVLEYP-AHEQVALLAAQPLLAG-SLYTVIIDYAANLS------ESFHGFYKSTYRTQEGEM--RILAATQFEPTAARMAFPCFDEPALKASFSIKIKRD-PRHLAISNMPLVK---SVNVAEGLIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSG-----VKVSVYAVPDKIN--QADYALDAAVTLLEFYEDYFNIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESSLLYDK-EKSSASSKLGITMIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVT---VTHPELKVEDYFFGKCFN-AMEVDALNSSHPVST----PVENPAQIREMFDDVSYEKGACILNMLRDYLSADTFKRGIVQYLQK---YSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRSQHSSSTSHWRQEVVDVKTMMNTWTLQKGFPLITITVSGR-------NVHMKQEHYMKGSERFPETGYLWHVPLTFITSKSDSVQRFLLKTKTDVLIL---------------PEAVQWIKFNVGMNGYYIVHYADDGWASLSGLLKE--AHTTISS----NDRASLINNAFQLVSIEKLSIEKALDLTLYLKNETEIMPIFQALNELIPMYKLMEKRDMIEVETQFKDFLLKLLKDLIDKQT-----WTDEGS-VSERMLRSQLLLLACVRNYQPCVQRAERYFREWK---SSNGNMSIPIDVTLAVFAVGAQNTEG---WDFLYSKYQSSLSSTEKSQIEFSLCTSKDPEKLQWLLDQSF-KGEIIKTQEFPHILTLIGRNPVGYPLAWKFLRENWNKLVQKFELGSSSIAHMVMGTTDQFSTRARLEEVKGFFSSLKEN-------------------GSQLRCVQQTIETIEENIRWMDKNFDKIRLWLQKEKPELL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ08-1", "uniprot_id": "ERAP1_HUMAN", "id": "Q9NZ08-1", "name": "Endoplasmic reticulum aminopeptidase 1", "aln": "-----------MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQST----------------------------EASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLT-----FWGTTKVEITASQPTSTIILHSHHLQIS------RATLRKGAGERLSEEPLQVLEHP-RQEQIALLAPEPLLVG-LPYTVVIHYAGNLS------ETFHGFYKSTYRTKEGEL--RILASTQFEPTAARMAFPCFDEPAFKASFSIKIRRE-PRHLAISNMPLVK---SVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSG-----VKVSVYAVPDKIN--QADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDA-EKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVS---VTHPELKVGDYFFGKCFD-AMEVDALNSSHPVST----PVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQK---HSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR-------NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLIL---------------PEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKG--THTAVSS----NDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQT-----WTDEGS-VSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWK---ESNGNLSLPVDVTLAVFAVGAQSTEG---WDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESF-KGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKEN-------------------GSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16406-1", "uniprot_id": "AMPE_MOUSE", "id": "P16406-1", "name": "Glutamyl aminopeptidase", "aln": "MNFAEEEPSKKYCIKGKHVAIICGVVVAVGLIVGLSVGLTRSCEQ------DTTPAPSQPPPEAS--TALPPQDQNVCPDSEDESGEWKNFRLPDFINPVHYDLEVKALMEEDR-----YTGIVTISVNLSKPTRDLWLHIRETKITK-----LPELRRPSGEQVPIRRCFEYKKQ-EYVVIQAAEDLAATSGDSVYRLTMEFKGWLN------GSLVGFYKTTYM-EDGQI--RSIAATDHEPTDARKSFPCFDEPNKKSTYSISIIHP-KEYSALSNMPEEK---SEMVDDNWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRSG-----KPLKVYVQPNQKE--TAEYAANITQAVFDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFLGVN---HAEKDWQMLSQVLLEDVFPVQEDDSLMSSHPVVV----TVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKK---FQFANAKTSDFWDSLQEAS---------------------------NLPVKEVMDTWTSQMGYPVVTVSGRQN----ITQKRFLLDSKADPSQPP-SELGYTWNIPVRWADNDNSRITVYNRLDKGGITLN-------------ANLSGDAFLKINPDHIGFYRVNYEGGTWDWIAEALSS--NHTRFSA----ADRSSFIDDAFALARAQLLNYKIALNLTMYLKSEEDFLPWERVISSVSYIISMF--EDDRELYPMIETYFQGQVKPVADLLG-----WQDTGS-HITKLLRASILGFACKMGDREALGNASQLFDSWL---KGSASIP--VNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVKLLARYLEMLK-DPNIIKTQDVFTVIRYISYNSYGKTMAWNWIQLNWDYLVSRFTINDRYLGRIVTIAEP-FNTELQLWQMQSFFAKYPNA-------------------GAGAKPREQVLETVKNNIEWLNVNRQSIREWFASLP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50123-1", "uniprot_id": "AMPE_RAT", "id": "P50123-1", "name": "Glutamyl aminopeptidase", "aln": "MNFAEEEPSKKYCIKGKHVAIICATVVAVGLIVGLSVGLTRSCEP------GTTPAPSNPPPHTS--TALPPQDQNVCPDSDDESGEWKNFRLPDFIQPVHYDLEVKVLMEEDR-----YTGIVSISVNLSKDTRDLWLHIRETRITK-----LPELRRPSGEQVPIRRCFEYKKQ-EYVVIQAEEDLAATSGDSVYRLTIEFEGWLN------GSLVGFYRTTYT-EDGQT--KSIAATDHEPTDARKSFPCFDEPNKKATYNISLIHP-KEYSALSNMPVEK---KETLDNDWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRSG-----KPLTVYVQPNQKQ--TAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVN---HAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVVV----TVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLEN---FKFKNAKTSDFWDSLEKAS---------------------------NQPVKEVMDTWTSQMGYPVVTVSGKQN----VTQKRFLLDYKADPSQPP-SALGYTWNIPIKWTENGNSNITVYYRSNREGITLN-------------ANLSGDGFLKINPDHIGFYRVNYEAETWDWIAETLSS--NHMNFSS----ADRSSFIDDAFALARAQLLDYEKALNLTRYLTSEKDFLPWERVISAVSYIISMF--EDDRELYPLIETYFRSQVKPIADSLG-----WQDTGS-HITKLLRASVLGFACKMGAGEALGNASQLFEAWL---KGNESIP--VNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLK-DPNIIKTQDVFTVIRYISYNSYGKSMAWNWIQLNWDYLVNRFTINDRYLGRIVTIAEP-FNTELQLWQMQSFFAKYPNA-------------------GAGAKPREQVLETVKNNIEWLKLNRKSISEWFTSMP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07075-1", "uniprot_id": "AMPE_HUMAN", "id": "Q07075-1", "name": "Glutamyl aminopeptidase", "aln": "MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDT-----YTGTVSISINLSAPTRYLWLHLRETRITR-----LPELKRPSGDQVQVRRCFEYKKQ-EYVVVEAEEELTPSSGDGLYLLTMEFAGWLN------GSLVGFYRTTYT-ENGQV--KSIVATDHEPTDARKSFPCFDEPNKKATYTISITHP-KEYGALSNMPVAK---EESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSG-----KPLTIYVQPEQKH--TAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP-KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVN---HAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIV----TVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEK---YQFKNAKTSDFWAALEEAS---------------------------RLPVKEVMDTWTRQMGYPVLNVNGVKN----ITQKRFLLDPRANPSQPP-SDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNS------------SNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSL--NHKTFSS----ADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMF--EDDKELYPMIEEYFQGQVKPIADSLG-----WNDAGD-HVTKLLRSSVLGFACKMGDREALNNASSLFEQWL---NGTVSLP--VNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLK-DTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEP-FNTELQLWQMESFFAKYPQA-------------------GAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFW9-1", "uniprot_id": "Q9VFW9_DROME", "id": "Q9VFW9-1", "name": "Aminopeptidase", "aln": "--MFLSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDK-----------------------IDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELYWHPDLETGN-----FTGQQRISIKVVEATNQIILHSYLLDITS-----VYVLNR------EVEKFELEEER-QFLIITLTEELAVDAS---ITLGIIFGGQMK------DKLVGLYSSTYLNEAGAT--RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTE---SNYLG-DYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQIN--KVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDP-SYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVN---AVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQ----KVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVK---HQFNNTVTDDFLTEVEAVVT--------------------------DLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVGIA--------------VPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTT--SPARFEI----ADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSL--MFS-EGYVSYLTYARSLIAGVYEEVG-----WTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL---ENPTTRPS-PDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPES-------------------GAGANSRLEAVETIKYNIEWLSRNEADITDWLSGTASPLTKKNQL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97449-1", "uniprot_id": "AMPN_MOUSE", "id": "P97449-1", "name": "Aminopeptidase N", "aln": "--MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSA---------------TAPTLPGSTSATTATTTPAVDESKPWNQYRLPKTLIPDSYRVILRPYLTPNNQGLYIFQGNSTVRFTCNQTTDVIIIHSKKLNYTLKGNHRVVLRTLDGTPAPNIDKTELVERT-EYLVVHLQGSLVEGRQ---YEMDSQFQGELA------DDLAGFYRSEYMEGDVK---KVVATTQMQAADARKSFPCFDEPAMKAMFNITLIYP-NNLIALSNMLPKE-SKPYPEDPSCTMTEFHSTPKMSTYLLAYIVSEFKNISSVSANG-----VQIGIWARPSAIDEGQGDYALNVTGPILNFFAQHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRESSLVFDS-QSSSISNKERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVEYLGAD---YAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSSPAD-EIKTPDQIMELFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHT---YQYSNTVYLDLWEHLQKAVNQQT-------------------AVQPPATVRTIMDRWILQMGFPVITVNTNTG---EISQKHFLLDSKSNVTRPS--EFNYIWIAPIPFLKSG-QEDHYWLDVEKNQSAKF--------------QTSSNEWILLNINVTGYYLVNYDENNWKKLQNQLQT--DLSVIPV----INRAQIIHDSFNLASAKMIPITLALDNTLFLVKEAEYMPWQAALSSLNYFTLMFD---RSEVYGPMKRYLKKQVTPLFFYFQNRTNNWVNRPPTLMEQYNEINAISTACSSGLKECRDLVVELYSQWM---KNPNNNTIHPNLRSTVYCN-AIAFGGEEEWNFAWEQFRNATLVNEADKLRSALACSKDVWILNRYLSYTL-NPDYIRKQDTTSTIISIASNVAGHPLVWDFVRSNWKKLFENYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKADNSATG-----------------FGTGTRALEQALEKTRANIDWVKENKDAVFKWFTENSS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15684-1", "uniprot_id": "AMPN_RAT", "id": "P15684-1", "name": "Aminopeptidase N", "aln": "--MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSA---------------IAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERT-EYLVVHLQGSLVKGHQ---YEMDSEFQGELA------DDLAGFYRSEYMEGGNK---KVVATTQMQAADARKSFPCFDEPAMKASFNITLIHP-NNLTALSNMLPKD-SRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNR-----VQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDP-QSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGAD---YAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPAN-EVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHT---FQYSNTIYLDLWEHLQQAVDSQT-------------------AIKLPASVSTIMDRWILQMGFPVITVNTSTG---EIYQEHFLLDPTSKPTRPS--DFNYLWIVPIPYLKNG-KEDHYWLETEKNQSAEF--------------QTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQT--DLSVIPV----INRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFD---RSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWM---NNSDNNPIHPNLRSTVYCN-AIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTL-NPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATG-----------------FGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15144-1", "uniprot_id": "AMPN_HUMAN", "id": "P15144-1", "name": "Aminopeptidase N", "aln": "--MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSP---------------VASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPT-EYLVVHLKGSLVKDSQ---YEMDSEFEGELA------DDLAGFYRSEYMEGNVR---KVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP-KDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNG-----VLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDP-LSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGAD---YAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPAS-EINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHT---FAYQNTIYLNLWDHLQEAVNNR--------------------SIQLPTTVRDIMNRWTLQMGFPVITVDTSTG---TLSQEHFLLDPDSNVTRPS--EFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLF--------------STSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQR--DHSAIPV----INRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFD---RSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWM---ENPNNNPIHPNLRSTVYCN-AIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTL-NPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETG-----------------FGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KI00-1", "uniprot_id": "Q0KI00_DROME", "id": "Q0KI00-1", "name": "Aminopeptidase", "aln": "--------------------MKWFLLFVAALGLGLATADSSADSIET---------------------------------------TYNYYRLPTSLRPQKYHLRILTLLENPEDLR--FSGSVKILIEALENTKNVTLHSKNLTIDESQ-ITLRQIGGEGKKENCVSSTAVNPSH-DFYILNTCQELLAGNT---YELYMPFAADLN------RQLEGYYRSSYKDPVANLT-KWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYH-KKYTAISNMPEKE-TKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHK--PSTLP---NSALFRTWARPNAID--QCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSA-AHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVE---NINPEWRSMEQESLSNLLTIFRRDALESSHPISR----PIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQK---FSYKNAEQDNLWESLTQAAHKYR-------------------SLPKSYDIKSIMDSWTLQTGYPVINVTRDYAAR---TAKLNQERYLLNTQVARAYRGG-CWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLP----GPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTN-GDFERIHV----INRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVR---QTPDFEFFKRYMKKLILPIYEHLNG-INDTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCT-SIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQS------------------LKGLEQAIQQTLEIMLTNVQWKERNYHQMSRSIQQLL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S7-1", "uniprot_id": "Q9W2S7_DROME", "id": "Q9W2S7-1", "name": "Aminopeptidase", "aln": "-------------------MHLSYLTILTALFFHLEANKTAVG------------------------------------------------RLPKWLVPLSYRVDIVTRINQPYQP---FGGTVVIDLRSERSTKRIVLNAHDLAIGKR---RAVTLSDKNGNSVPVSSIQMDIKL-SRLTVSLKRPLKVNVT---YSMRVAFTSVLR------NDNTGFYSSNYVDHNTTLT-QWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHP-YLYRALSNMPVQR-TIRHASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSER---SDCPISTWARPDALS--QTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDS-QRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVH---SLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTA----SVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVV---YANRTATSSDFWDLLQLQVDRNG-------------------RLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHR---TAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHR----VNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAK---SNPNYLIFKTYMRLLLERQFKRVIS-SDLTSSSG----NMTHRPVIIRLACEYELPACVSLARREFMKG----TPEKGGWMTIRERETVVCT-AVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFES-SGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRD------------------MNGSERLIKILLERGNDNIHWQRTKFRPMLQAIRDIILWRSRAKRILK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40462-1", "uniprot_id": "TM108_YEAST", "id": "P40462-1", "name": "Protein TMA108", "aln": "-------------------------------------------------------------------------------------MSDNLLSLENPVVPSHYELRLEIDPKQSSPN---FKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATD-AQYKAVSNTPVEM--VEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEG-DRTIPVSIYAPWDIAN---AAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLK--------------------------SQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMDTKNVLLTDRTLKFD------------------YPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDR--ASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTN---PHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQ----GPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * * : : * : . : : : : : . : * : : : . : *. :. * ***:*:* :: : :.: *:** * : * * :. : : . :. :: : : * * :* : : *::*: : *: : : : :.:**:** ::. * .:*::: ** :. : . : . :: *. ::. : . . : . .. :: : : .: * * *::.: . : *: : :* : * * : . : . :: : : : . . : . . : : . : . : : .: . : * . : : : . . :: :: : . ", "identical_positions": 41, "similar_positions": 136, "identity": "3.75%" }, { "cls_id": "homologset.agr.SGD:S000001404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIM9-1", "uniprot_id": "TCPB_RAT", "id": "Q5XIM9-1", "name": "T-complex protein 1 subunit beta", "aln": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDA-SLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK-KIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTMLASRTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGRITAGLDMKEGSIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P80314-1", "uniprot_id": "TCPB_MOUSE", "id": "P80314-1", "name": "T-complex protein 1 subunit beta", "aln": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDA-ALMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK-KIHPQTIISGWREATKAAREALLSSAVDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHITAGLDMKEGTIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78371-1", "uniprot_id": "TCPB_HUMAN", "id": "P78371-1", "name": "T-complex protein 1 subunit beta", "aln": "MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDA-SLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK-KIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W392-1", "uniprot_id": "Q9W392_DROME", "id": "Q9W392-1", "name": "T-complex protein 1 subunit beta", "aln": "-MEMSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQ-KLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPRRRVPDRGYC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39076-1", "uniprot_id": "TCPB_YEAST", "id": "P39076-1", "name": "T-complex protein 1 subunit beta", "aln": "------MSVQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSNT--CMVTNDGATILKSIPLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAALDALTKAAVDNSHDKTMFREDLIHIAKTTLSSKILSQDKDHFAELATNAILRLKGSTNLEHIQIIKILGGKLSDSFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFKVDSTAKLAQLEKAEREKMKNKIAKISKFGINTFINRQLIYDYPEQLFTDLGINSIEHADFEGVERLALVTGGEVVSTFDEPSKCKLGECDVIEEIMLGEQPFLKFSGCKAGEACTIVLRGATDQTLDEAERSLHDALSVLSQTTKETRTVLGGGCAEMVMSKAVDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRSSIYNGISTSGLDLNNGTIADMRQLGIVESYKLKRAVVSSASEAAEVLLRVDNIIRARPRTANRQHM--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.:: . **:** ***::*:****:***************:* ::. :: *********: : :******:**::*:***:************::*******.*: : *:*** *: *:* *: .* :** :* *:. .. * :**::** ******:* :.**.*::**.:*::***** :*: *::** **.*.**:*****:* ** * :**:*****:****** :****:*:**: .:*** **:*::* **:****:*: :* *. * ********:****** : :****** *:**** ****:.***:.*. ***.*.:**::*:**: :::*** *******:****:* ****:*******.**: *.*:.* : ****:* :*: ** * . **:::*:*::*:** *** :*****:**::**::**:. :* * ***:. *.:.*: ***.**: :** *: **:****::*******:. ** :: ", "identical_positions": 294, "similar_positions": 143, "identity": "54.75%" }, { "cls_id": "homologset.agr.SGD:S000001405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G005-1", "uniprot_id": "ERCC3_RAT", "id": "Q4G005-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDAPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTVE-GSGGASTSQGVDAQAK------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRFGTMSSLSGADDTVYMEYHSSR-NKAST-KHVHPLFKRFRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49135-1", "uniprot_id": "ERCC3_MOUSE", "id": "P49135-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDIPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGGPSTSQGVDAQAT------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRCGTMSSLSGADDTVYMEYHSSR-SKASS-KHVHPLFKRFRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19447-1", "uniprot_id": "ERCC3_HUMAN", "id": "P19447-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRADR--DKKKSRKRHYED-EED----DEEDAPGNDPQEA--------------VPSAAGK--QVDESGTKVDEYGAKD-----------------------YR----LQMPLKDDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAE-SSGGPSTSRVTDPQGK------SDIPMDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSSQASRRFGTMSSMSGADDTVYMEYHSSR-SKAPS-KHVHPLFKRFRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVV1-1", "uniprot_id": "ERCC3_DANRE", "id": "Q7ZVV1-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--RKDKSDR--EKK-SKKRYYED-EEE----DEE-VIGGESQEA--------------VPAAAGK--QVDESSTKLDEYGAKD-----------------------YR----LQMLLKNDHSSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAISEPVCRPTHAHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKHNRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETELITETISSKSAISKSQQ-DNGGPSSSQPADGQRSG-----TQVPEDIFSYYEQMDKEEEEEEET--QTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLMFSTRDEQQQLLQKVLAASD--------LDAEEEVVMGEVG---GKP-QFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02870-1", "uniprot_id": "ERCC3_DROME", "id": "Q02870-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MGPPKKSRKDRSGGDKFGKKRRAED-EAFTQLVDDNDSLDATESEG--------------IPGAASKNAETNDEQINTDEYGAKD-----------------------YR----SQMQLRPDHGNRPLWVAP-NGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEVLQKLLKDPVIQKCRLIRSEGE--DFIQGTLDGK-AITQFGTKLPPGATDKPTPDPAAAAGADGTTAVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPDINIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWKQQFKMWSTADDSMICRFTSEAKDK-PMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKGMDTDSDLMYGTQEEQGQLLQLVLSASD--------LDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDAIYYEHRKKN------IGSVHPLFKKFRG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00578-1", "uniprot_id": "RAD25_YEAST", "id": "Q00578-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2", "aln": "MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDS--------DHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEA------------VFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKR-RNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNG-HKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNK---NKELKEHHPLIRKMYYKNLKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.: . . *: *:: . .*. * * . . :: .*** :* : *: ** .****::* :*:::**:***: : *:***::*:**:.** * ****:*************:* ** . * :***. :.:.*::**: .*:********:***:**:*: .:::* **:*.** *: . : .: : .: . : : . *::.*:*:: . ***: :* :* ::*** :::*:* ******* ***:::****:: :******** ***********:*********:***:**.**::* :** .*.*** **: ** *.* : . . ***: *: ..: ::****: :* :** ::::.* :: :***:::*****.:** *****:: : :*.********:****** ***************:**.::*:**.**********:.***:**: .: *::*** ***.**::*****::**:*.** ***:***:**:.**:::.**:***.*.* **::*****:.* ::****:***.***:*****. ******* ************:****: * :**:**:***:** ** ** *** ***:***::****:* **: :* :.: *: :*** ** .: *.::. *. * * * :*.::*.:* * *: . ***:::: ", "identical_positions": 367, "similar_positions": 214, "identity": "42.28%" }, { "cls_id": "homologset.agr.SGD:S000001406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K254-1", "uniprot_id": "A0A0G2K254_RAT", "id": "A0A0G2K254-1", "name": "Kinetochore protein NDC80", "aln": "------MKRSSVSSCGAGRLSMQELRSLDLNKPGLHTPQT-ERSTFGKLSTHKP------------TSERKVSIFGKRTS--------EHGSRN-------SQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTEN----GYVYSVSMKSLQAP------STKDFLKIFAFLYGFLCPSYELPDTKCEEEVPRIFKELGYPFALSKS-SMYTVGAPHTWPHIVAALVWLTDC---IKIHDAMKQSS-----------PLFDDGQAWGEETEDG-----IKHNKLFLDYTKKCYEKFMTGADTFEDVDAELQAKLKDLYKVDASKLESLVEENKALNEQIARLEQEREKEPNRLISLRKLKAS-LQADVQNYKAYMSNLESHSSILEQKLSSLDEEIGRLELECETVKQENTRLQSVVDNQKYSIADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLK--------------LIPKGAENSKGYDFEIKFNPEAGAN------CLVKYRTQVYAPLKELLNEIEEEINKALNKKMGLEDTLEQLNTVKTESKRAVRMLKEEVQKLDDLYQQKVKEAEEEDKKCASELDSLEKHKHLLESAVNEGLSEAMGELDAVQREYQLAVQTTTEERRKVGNNLQRLLEMVATHVGSLEKHLEEQIVKADREYEECTSEDLLEN-IRRIAEKYKSNAAQLKAPDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0F1-1", "uniprot_id": "NDC80_MOUSE", "id": "Q9D0F1-1", "name": "Kinetochore protein NDC80 homolog", "aln": "------MKRSSVSTCGAGRLSMQELRTLDLNKPGLYTPQTKERSTFGKLSTHKP------------TSERKVSIFGKRTS--------GHGSRN-------SQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTEN----GYVYSVSMKSLQAP------STKEFLKIFAFLYGFLCPSYELPGTKCEEEVPRIFKALGYPFTLSKS-SMYTVGAPHTWPHIVAALVWLIDC---IKIDTAMKESS-----------PLFDDGQLWGEETEDG-----IKHNKLFLEYTKKCYEKFMTGADSFEEEDAELQAKLKDLYKVDASKLESLEAENKALNEQIARLEEEREREPNRLMSLKKLKAS-LQADVQNYKAYMSNLESHLAVLKQKSNSLDEEIGRVEQECETVKQENTRLQSIVDNQKYSVADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLK--------------LIPKGAENSKGYDFEIKFNPEAGAN------CLVKYRTQVYAPLKELLNESEEEINKALNKKRHLEDTLEQLNTMKTESKNTVRMLKEEIQKLDDLHQQAVKEAEEKDKKSASELESLEKHKHLLESGVNDGLSEAMDELDAVQREYQLTVKTTTEERRKVENNLQRLLEMVATHVGSLEKHLEEENAKADREYEEFMSEDLLEN-IREMAEKYKRNAAQLKAPDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14777-1", "uniprot_id": "NDC80_HUMAN", "id": "O14777-1", "name": "Kinetochore protein NDC80 homolog", "aln": "------MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKP------------TSERKVSLFGKRTS--------GHGSRN-------SQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTEN----GYAHNVSMKSLQAP------SVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKS-SMYTVGAPHTWPHIVAALVWLIDC---IKIHTAMKESS-----------PLFDDGQPWGEETEDG-----IMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLKAS-LQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLK--------------LIPKGAENSKGYDFEIKFNPEAGAN------CLVKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSEN-IKEIRDKYEKKATLIKSSEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRJ7-1", "uniprot_id": "NDC80_DANRE", "id": "Q6DRJ7-1", "name": "Kinetochore protein NDC80 homolog", "aln": "------MSRRPSS-----RYSEMPMRVTDSRMSLINATPQNKDNAFGKLNIPKPQS---------TTSERRTSFFGKGIG--------AGGQRN-------SMFGSYGGSEKMKDPRALHDKAFVQQCIKQLYEFLVDR----GFPGSITVKALQSP------STKEFLKIYEFIYNFLEPSFQMPTAKVEEEIPRMLKDLGYPFALSKS-SMYSIGAPHTWPLALGALIWLMDA---VKLFGGQREQD-----------LLFSDFSDELCDLEDR-----TEYNKLIMEYCSDTYNKFMQGADTFDDEDDDFLYKLKKLYNVDEALLHSQQEKHSMLMEHVERLE--RESQTDRLVGKRTEKLR-LQTDLQKLQNYRCTLEAHKTGLENKSAGLTEELEAVEMQLEGLKQERTRLQHILENQKFTPADIERINRERNELQQTIHGLSQSLEEGEQLVWNEEVNLSKTKEKAELKVAEYNKLGRKLK--------------LIPLSAENACGHDFEIR--ADYSAT------TITQYKTQIQNPLKNMMVEVEEEFSRLSNVNLSLEETVEQVKSNIFDKENDIKQLKEQIRKVDQQLENAMQEMALEDDKWAAELDSAETHKKLFEKNVMQGIEEAEEEVKAAQQQYHVVVQETNEKNRMVVKNMTDLFSSTVNHLFAVEKHCDEQLKRFDKLKDIVREDEADINQLTDLVENFIKKANSL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40460-1", "uniprot_id": "NDC80_YEAST", "id": "P40460-1", "name": "Kinetochore protein NDC80", "aln": "MQSSTSTDQHVLHHMDPHRFTSQIPTATSSQLRRRNSTNQGLTDMINKSIARNTISGTGIPTGGINKNKRTRSTVAGGTNGTALALNDKSNSRNSVSRLSINQLGSLQQHLSNRDPRPLRDKNFQSAIQEEIYDYLKKNKFDIETNHPISIKFLKQP------TQKGFIIIFKWLYLRLDPGYGFTKS-IENEIYQILKNLRYPFLESINKSQISAVGGSNWHKFLGMLHWMVRTN--IKLDMCLNKVDRSLINQNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELKLGFEKFVHIINTDIANLQTQNDNLYEKYQEVM----KISQKIKTTREKWKA-LKSDSNKYENYVNAMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREKLTRELDKINIQSDKLTSSIKSRKLEAEGIFKSLLDTLRQYDSSIQNLTRSRSQLGHNVNDSSLKINISENLLDRDFHEGISYEQLFP------KGSGINESIKKSILKLNDEIQERIKTIEKDNITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKINDSNLLMKTKISDAEELVTSTELKLEELKVDLNRKRYKLHQQVIHVIDITSKFKINIQSSLENSENELGNVIEELRN-------LEFETEHNVTN---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VYB1-1", "uniprot_id": "Q9VYB1_DROME", "id": "Q9VYB1-1", "name": "Kinetochore protein NDC80", "aln": "------MSHLMPRRTSEFRGDVLEERGTADKRQTRATKRSAATHTPSSSQAAPRRP----------SASRLPQPLNLERD--------RASQMG----VTPKRGHRFVPSTAERAIAPHSDKKWVAERAQQILEYLHGIQ-NSEAPTGLIADLFSRPGGLRHMTIKQFVSILNFMFHHIWRNRVTVGQNHVEDITSAMQKLQYPYQVNKS-WLVSPTTQHSFGHVIVLLDFLMDFLPPLPSSDVVEEEFPFMETMEQPSSYLNSMHCESTTIMSTTQAHAIQLDEDVNGLLFEEASKCIALWDQELTNEEAKLQAETRDQVISKKCDLPDRKALDQLIGDLKTKLQQLENKLHDPSEDNKLNKLERLTKEHDQLAQQLAASEEELIKKLKLYEQLSAQVEEKQSNLRQQMKYEKRLEQAVNRQKFSAQQLKELQMKCDDMENYSKAYERQVKEVSELELHQQVMLSRAKQKQLDSVEVFNSHVRHLSMDPVICG-------LIKSGIGQQSDLTLPLNPNQEDISERVQCLELLGKLLQQHRQQNIDRRQMLDKQVAKVKSDSIELDTEIATMDSQLRAQKQRLTKMEASYRTKRDMQAQHRQQLLEDQYDQTARLDELEKREKQALEKLEASKQRNEDLLTAAEQFQEQDLKARQDR----LEKCEQKLAKAEDQLLAVESKVNATQAKLNEVEQKVYSAKLPS--FQPVLDAIKNH---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * . : .. . .* . . . .. . . : . ** : .:: ::* : . :. * : * *: * ::: : . ::: :: * **: . . : .: : * :: : .: : . . :.: . : : : .: .. : . . : : .: : : * : :: : . : : : : . . ..*. : .: : ::: : : :.: . . . . . .:: : : :.. ::*. * : . : : . . ::.. . . *: : :. . . :: . . :: .::. *.: : : . : :.: . . :: : . ::. : . .. : . : : : ", "identical_positions": 19, "similar_positions": 171, "identity": "2.61%" }, { "cls_id": "homologset.agr.SGD:S000001410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62987-1", "uniprot_id": "RL40_HUMAN", "id": "P62987-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62984-1", "uniprot_id": "RL40_MOUSE", "id": "P62984-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62986-1", "uniprot_id": "RL40_RAT", "id": "P62986-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18101-1", "uniprot_id": "RL40_DROME", "id": "P18101-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRILAQKYNCDKMICRKCYARLHPRATNCRKKKCGHTNNLRPKKKLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CH08-1", "uniprot_id": "RL40A_YEAST", "id": "P0CH08-1", "name": "Ubiquitin-ribosomal protein eL40A fusion protein", "aln": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************.****:***:******************************************************: **.****** :******** ***.****:******:******:*", "identical_positions": 115, "similar_positions": 10, "identity": "89.84%" }, { "cls_id": "homologset.agr.SGD:S000001411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA98-1", "uniprot_id": "TPR_RAT", "id": "F1MA98-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAAVLQQVLERPELNKLPKSTQNKLEKFLAEQQSEIDCLKGRHEKFKVESEQQYFEIEKRLSQSQERLVNETRECQNLRLELEKLNNQVKVLTEKNKELETAQDRNLGIQSQFTRAKEELEAEKRDLIRTNERLSQEVEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVTVKYREKRLEQEKELLHNQNSWLNTELKTKTDELLALGREKGNEILELKCTLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDLLSATKR-----KGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSAKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNH--VIRDEEVSSADISSSS---------EVISQHLVSYRNIEELQQQNQRLLFALRELGETREREEQETTSSKIAELQNKLENSLTELEQLRESRQHQMQLVDSIVRQRDMYRILLSQTTGMAIPLQASSLDDISLVSTPKRSSTSQTVSTPAPEPIIESTETIEAKAALK-------QLQEIFENYKKEKMDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATLKQHLNNMEAQLASQS----TQRTGKGQPGDRDDVDDLKSQLRQAEEQVNDLKERLKTSASNVEQYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLTELKKTLSSVQSEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDLEKQNRLLHDQIEKLSDKVVTS----------------MKEVVQSPLNISLNEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQNLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLINQQKDPDTEEYRKLLSEKEIHTKRIQQLNEEVGRLKAEIARSNASLTNNQNLIQSLKEDLSKVRTEKESIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEELKAQQ-KAMETSTQSSG-DHQEQHISVQEMQELKDNLSQ-SETKTKSLEGQVENLQKTLSEKETEARSLQEQTAQLQSELSRLRQELQDKTTKEEQLRQQMNEKDEKTWKAITVARSKIAHLSGVKDQLTKENEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-TNKAPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGSTSGSVRSTSPNVQPSISQPLLTVQQQTQATAFVQPTQQSHPQIEPANQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRAREEEEDSTIEAGDQVSDDTVEMPLPKKLKTVTPVGTEEEVMAEESTDGEAETQTYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQ-TTSSQDG-QGKGDDVIVIDSD------DED-DDEENDGEHEDYEEDEDEDDDEEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGAESNQRAADSQNSGEGNTSAAESSFSQEVAREQQPTSASERQTPQAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETPAGDDGDEVFV-ETESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGISHAMGGRGGINRGNIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6ZDS4-1", "uniprot_id": "TPR_MOUSE", "id": "F6ZDS4-1", "name": "Nucleoprotein TPR", "aln": "MTSGGSASRSGHRGVPMTSRGFDGSRRGSLRRAGARETASEAADGAAPAAGLRASPCSLASPSAAAAVAAIPADMAAVLQQVLERPELNKLPKSTQNKLEKFLAEQQSEIDCLKGRHEKFKVESEQQYFEIEKRLSQSQERLVTETRECQNLRLELEKLNNQVKVLTEKTKELETAQDRNLGIQSQFTRAKEELEAEKRDLIRTNERLSQEVEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVAVKYREKRLEQEKELLHNQNSWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDLLSATKR-----KGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKQENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSAKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNH--VIRDEEVSSADISSSS---------EVISQHLVSYRNIEELQQQNQRLLFALRELGETREREEQETTSSKIAELQHKLENSLAELEQLRESRQHQMQLVDSIVRQRDMYRILLSQTTGMAIPLQASSLDDISLLSTPKRSSTSQTVSTPAPEPVIDSTEAIEAKAALK-------QLQEIFENYKKEKIDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLNSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATLKQHLNNMEAQLASQS----TQRTGKGQPGDRDDVDDLKSQLRQAEEQVNDLKERLKTSTSNVEQYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSTVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMTSIRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDLEKQNRLLHDQIEKLSDKVVTS----------------MKDAVQAPLNVSLNEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNVEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQNLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQQLINQQKDPDTEEYRKLLSEKEIHTKRIQQLNEEVGRLKAEIARSNASLTNNQNLIQSLREDLSKARTEKEGIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEELKAQQNKAMETSTQSSG-DHQEQHISVQEMQELKDTLSQ-SETKTKSLEGQVENLQKTLSEKETEARSLQEQTVQLQSELSRLRQDLQDKTT-EEQLRQQMN---EKTWKTLALAKSKITHLSGVKDQLTKEIEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-TNKAPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGNASGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPTNQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTMEAGDQVSEDTVEMPLPKKLKMVTPVGTEEEVMAEESTDGEAETQAYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQ-TTSSQDG-QGKGDDVIVIDSD------DED-DDEENDGEHEDYEEDEDDDDDEEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGAESHQRAADSQNSGEGNTSAAESSFSQEVAREQQPTSASERQTPQAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETAAGDDGDEVFV-EAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGISHAMGGRGGINRGNIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12270-1", "uniprot_id": "TPR_HUMAN", "id": "P12270-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKR-----KGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNH--VIRDEEVSSADISSSS---------EVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALK-------QLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS----SQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVAS----------------VKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSG-DHQEQHVSVQEMQELKETLNQ-AETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-SNKVPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSSQDG-QGKGDDVIVIDSD------DEEEDDDENDGEHEDYEEDEEDDDDDEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGGEGNHRAADSQNSGEGNTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETATGDDGDEVFV-EAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGVSHAMGGRGGINRGNIN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ68-1", "uniprot_id": "A0A8M3AQ68_DANRE", "id": "A0A8M3AQ68-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAALLQQALERTEVNKLPKAIQNKLEKVLAEQQTEIDSLISQHERYKADCEQQYFNLEKKLAESQEQFLSQSKDYHNIKEENNRLVEELKKLKEIEEVQGTTQE------SKPPRAKYEIEAENRELSRLLEKRSQEVENLSEDLKRLNDKLVETNTIKMELQLKLDELQSSEVSIQYREKRMEQEKELLQNQNTWLNTELKSKTDELYTVSRDKGKENLELRCSLESKKEEVTRLQDQVNTLKKANDSMQKSTEDLMRKLKEAKEQRASMEEKYRNELNANLKLCNLYKGAASDSEAKNTELNRAVEELNKLLKEAMEANKGTEKKLSELQSVREKAESDLREKVRHLEKELENSNTRLADFKR-----RGVPALTEEELTNLSPTAAAVAKIVKPGMKLMELYNAFVEAQDQLHLEKLENKRVNKVLDEIVLEVETKAPILKRQREEYESMQKSMTSLCYKLEQAMKEVHRLQKETDEANKRALVLERDNQKSERQLADMSEQVRVLLVEVEEARGNQ--VVR-EDVSSA-VSSSS---------EVQGSRQVAFRSIQELQQQNQNLLVKIRDLEEQREKDQNQAKSAKQTELEQSLEKVQKELEQIKEQQNHQKLLAESAIRQRDMYRILL-QTAGVELPPQGS--DGGSQSTTPSRPGPMATRSTPLRAAAAESFQATQSKAALK-------QINDAFTTYKKEKAENDKLLNEQIERLRGQVSDLLSQKAKLSSQLEFASKRYDMLQENVNGFRRETEALRERNQKMSATHQRHEQIIHTMTQDLREANEKLTMSESRAENIRKERDILKQVENRLNQEKESILTEQRSQNLLLTNLKSIQLTMERSETETKQRYNNQIQHLEKEIIQLKKRLEQEVEQRHALERNQDTQLLEAKKKLESQTALHQKTKELLRSAEQQVTSLRQQLNNNENQSAAPKQPVRTLPRVSAPSVPQQEADDLRARLQQVEEQNSDLKERLKNTTTNVEQYRSMVLSLEESVNKEKQLAEQARTSTDNQLKMARELNQQLEARLVEAEKEKLELQQEKMKAVDSVEERVKELKRSMTNMQTELQEALQRSTAAVTQEQKATQDSKVQAKLAAEAQNKYERELMLHAADVEALQAAKKQGLLLTQNMKQLEEKAQKAASELHQYRTDWVMQEKRLKETLSKEQKRAEELQKQNTLLHEQMENLSSKITAST---------------QQETGESSLNISLNEEGKSHEQILDILRFVRREKEIAETRLEVAEVETLRYKQRMEYLECELKELQDSLNVEREKLQVTTKTLVQQEETMKRMESMSALTETNKMLKNEKNRLEHELQQTQAKMRKLEADIKPLQEANGELSEKSGMLQAEKRLLEEDVKRLKSRTQQLLNQQKDSDQEESKKLHSERETHLKRIQQLTEETGKLKNEVARSQASITTAQSQVQNLQDSLGKVTTERDSLKKELEAKTLDIQEKVKTITQVKKIGRRYKTQYEELKEQHDKMVAEAASKPAQEQEDRQASVQEIQNLKSSLSQ-TQNRTSELETQLDCIQKTLQEREAEVKSLQEQLTQVQPELSRLKAELQDKGKLEEQLRQQIADKEEKTKKAFLGAKQKLNQLNSAKEQLAKENEELK-------LQREELEVRMSALKSQYEGRLSRQERELRELREQQERHGEQRDEAQEPGQSKVQEAPRSSDARQITLKPTPAAD-RGSASQSEPPTANIKPTLVAATPSKP--SPIAGSKSTPKASIRPMITPAPVT----TPTATVMPTTQVETQEALQSTEGPLEHVTVFGSTSGSVRSTSPNIQT--TQPILSLQQ-SQATAFVQPTQQ------QASQEPATSIMEAVHSSQMERPSTSTAVFGTVSATTGSSVAKRVREEHEESSTEVTDTTQDDSTHPPIMKKLRIVRRVGLEDASGTEESNDAMGESSGDVQQPPD-----ASEEAYPVLGEGDEESLSVPMDQVSESQPSESQISGQDSSEEYKHDVIVIETDSATEEEEEEEEEQEEPGQYEDDDEDEDDDAEDEDDEDGDGGMAEAAEESNEGSGSADANEAYEGDEAEQGAGEADPSVHNEESQEASDSTQKQPDSQSSEASVSTLEAFPLEPVREHPPLPSTTTTSLAPRLPQSPRRPHHTPPPRLNIHPVP-ELGPPIMQRQSGQSRRPSMS-RAPQLTPGIG-SMQHFFDDDDRMVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMMPQASSSHSDLSHLATHGGLGMYESPLFLPTHDEESGGRSVPTTPLQVAAPVTVFTESHPSDVSETASQSVPMVSTSTASLSAPGEAVPGDDGDDVFVAEAESEGVSSEACLEG--QLELDSAQPADDASLPSTSQEPTSSSADTSTSSGQAKPAGRLLPQHHLPR----RNQLIRRGFPRGGRGRG-LSRGSPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8P9-1", "uniprot_id": "TPR_DROME", "id": "A1Z8P9-1", "name": "Nucleoprotein TPR", "aln": "----------------------------------------------------------------------MDLSGPQTLNNILQPDELKLVPEDVQKKLSEYINN-FSDEYCKNRAAANRLAEAEQKKEELENKMEDYLVKFTSFELNVNELRTHLDQMSSERVNLMDTIAKGEQTIS-------QLRKEKASVVEERDSMMKVIERQQAELERLKQDLHTYQQQLSSAIAAKCEAIARVDEIQSKEVALELKENRMESERDMLHKEILLISGDLNKSNAELQNIRREHTINTMQLQSCLKEKTESLKLMQEQYEQAVKTIGELTSKIEMQNDTAFKQNQATEEYVGKLKKELDAKEKLFEIFKSTESDHLIQREELLQGISEIKRLLEEAEEQCAQLTEQMETMKQKHSAELDEQNKKIQAMEQELASANDLLKQARE-----SNL----ESAICQLAPSAAVASRLIRSDLSLTELYSMYAKSSEELEMRNCEIEQLKLQLKSIIAEISESAPILEKQNSDYQKMKETNSELLREHDELLQNKLCLERELERALSTLNHNQNENKKLKQTHTDLSRQVCMLLDELNCIRAG---VKHVRIQPTRQLPTSE---------SLISDNLVTFSSIEELVDRNTYLLNMSRELTELLEASEKNQDKMLLEQSKNHIRKLDARFAELEDLLTQKNNTVTTLLSKCDRYKKLY-FAAQKKLGQNTVDLDDSNLEPNDSALDTSEQPAANFEESRKLEKRVRQLEQQLEGEVKKYASLKENYDYYTSEKRKNDALAQEQFDSMRKEVRELTSSNCKLMNTTEFQKEQIELLHKNIGTYKQQVTTLEERTKNYEKTIIKHEQTVHLLKDEMMAAHRKHAAADAEAQSLRQENRILRDTSSRLQIEKETYHREQQSQSLLLNSLEFIKTNLERSEMEGRQRLEQRLDDTVRELAAQRRHFQEEEEKFRESINEFKRQAETAIKLKDEEKQLADKWQAELTSVREELAEKVNKVNELSKKLQEVLT---PTLNDNPITAANKRAREFELKLDQATVEIESLTKELAKTREHGEQFYKMSQSAESEIKRLHELHGELVAKQEEEIKKLRSSEAELKTRISDLEAEAMLSN-------VTEQSKTVNQSGQLKSAQDDLKSLLEKLTEANCTIRTLRSENTSLVESLNAAEVKYANGMIQHSADIQELTRYKAEFFKANDELNQLKSGRESLQAAYDELLRSNAEAQKLLDKEREESEKRVADLHALNSNLHDQIEALASKLAVLASQSQNPNSSLNESAMDGDQSLNASGLTAAEEGRNNEQLLKIIKFLRKEKDLFAAKLDILKAENARLISEHAIQQKKVDELNGYLNQERAKSQTDVVSANKHEEVLRKIETLNAITDSNRILREERNALTLRVAELTDRISSVEKELFPLQCSNKELTSKIEEINVENTSLRTEAIKWRQRANALVEKS-NRNPEEFKRLQAEREHLAKLLTAEKELNKKQSDELTVLKQRMNTEIPMLNKQMQILDEARK------KQVDEFTNLKQNNTRQTQDIMELKNRLLQKEEELLKANEELETKDKTIADKETKELQLRKLAKRYKDFYIGLQSQGGGTESAAELEKVRSELEEVNNQLRALKDEHEKITKECDEVKKRT-EPETDTSAIRQEYKAKLDKLVVDLTVARTDLVN----------------------------QETTFAGTKSSYDETIARLEKELQENIAANKDINQRLTRENESLHMRINQLTRQLGSQQSTKPSTSSVAEKGNISESSPRTANVKPMSGSATVQQSATVTPWRGGETPLASIRPISVQNSRTAAILPTSQQPPAGSSTSTSSSSSSSSTSTTSAAGGGSSAVAQTALVPPQQQVHTTGSAALESMASSSPTSSHTDY------MPSTSSASVAVAAIPPMGASSAAESSQEAESIQHPQQNDSQLFVGGAQQQVVALVSPRVEGSSSSSSSTSVPTATAPSIQDGGSQSQQPSTSGSSSSSSTVVSSHSRHTPSSSNVTTTQAGCSSQGIKRPRDIEGDSSTGTEEGVAEKMSKITKRLRGPMHSG-------ELSAGHIGDSGMDVDQMPTSSQRDQEDD----IQVVDSDDEEDVLADADDGPIDGGEAEQEGYEDSYEQDNEMDDNEGGDDDNDIAVDAQDNNEVDIEVPEQHMQAQEESQSLDNQAIATASASTQENNQSQAITSGSGESSNPVTLPQAEASNWKQAAASTSTAAARRNESSVEIVSSPQVSNFCEQPARLESAEVDGTAEVAGGAPHESAGPSDTGAASASS--PQKQSEAGESSGSDALKAADDGGDHADGTDNAR-EADEAFAEETMATGQGEDSQPLGNDNPNVGTSQSEVSHNQANLGEGNPTEDSEGADGVSSEGEKQAVGVEEEGREAEATSPSENTRFRTLRSAVPTRRGHRAMRGGSPNSQNRPQRIVWQRDTSPGNIQQNQMSANNNRFAQRTRNRRPIRRPPPNNFNNGGRFP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40457-1", "uniprot_id": "MLP2_YEAST", "id": "P40457-1", "name": "Protein MLP2", "aln": "----------------------------------------------------------------------------------------------MEDKISEFLNVPFESLQGVT-------YPVLRKLYKKIAKFERSEEEVTKLNVLVDEIKSQYYSRISKLKQLLDESSE-------------QKNTAKEELNGLKDQLNEERSRYRREIDALKKQLHVSHEAMREVNDEK-RVKEEYDIWQSRDQGNDSLNDDLNKENKLLRRKLMEMENILQRCKSNAISLQLKYDTSVQEKELMLQSKKLIEEKLSSFSKKTLTEEVTKSSHVENLEEKLYQMQSNYESVFTYNKFLLNQNKQLSQSVEEKVLEMKNLKDTASVEKAEFSKEMTLQKNMNDLLRSQLTSLEKDCSLRAIEKNDDNSCRNPEHTDVIDELIDTKLRLEKSKNECQRLQNIVMDCTKEEEATMTTSAVSPTVGKLFSDIKVLKRQLIKERNQKFQLQNQLEDFILELEHKTPELISFKERTKSLEHELKRSTELLETVSLTKRKQEREITSLRQKINGCEANIHSLVKQRLDLARQVKLLLLNTSAIQETASPLSQDELISLRKILESSNIVNENDSQAIITERLVEFSNVNELQEKNVELLNCIRILADKLENYEGKQDKTLQKVENQTIKEAKDAIIELENINAKMETRINILLRERDSYKLLASTEENKANTNSVTSMEAAR------------------------EKKIRELEAELS--------------STKVENSAIIQNLRKELLIYKKSQCKKKTTLEDFENFKGLAKEKERMLEEAIDHLKAELEKQKSWVPSYIHVEKER------ASTELSQSRIKIKSLEYEISKLKKETASFIPTKESLTRDFEQCCKEKKELQMRLKESEISHNENKMDFSSKEGQYKAKIKELENNLERLRSDLQSKIQEIESIRSCKDSQLKWAQNTIDDTEMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTK----------FQYKFLDQNSDASTLEPTLRKELEQIQVQLKDANSQIQAYEEIISSNENALIELKNELAKTKENYDAKIELEKKEKWAREEDLSRLRGELGEIR--------ALQPKLKEGALHFVQQSEKLRNEVERIQKMIEKIEKMS---TIVQLCKKKEMSQYQSTMKENKDLSELVIRLEKDAADCQAELTKTKSSLYSAQDLLDKHERKWMEEKADYERELISNIEQTESLRVENSVLIEKVDDT----------------------------------AANNGDKDHLKLVSLFSNLRHERNSLETKLTTCKRELAFVKQKNDSLEKTINDLQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKENNAILQKSLKNVTEKNREIYKQLNDRQEEISRLQRDLIQTKEQVSINSNKILVYESEMEQCKQRYQDLSQQQKDAQKKDIEKLTNEISDLKGKLSSAENANADLENKFNRLKKQAHEKLDASK---------------------------KQQAALTNELNELKAIKDKLEQDLHFENAKVIDLDTKLKAHELQSEDVSRDHEKDTYRTLMEEIESLKKELQIFKTANSSSDAFEKLKVNMEKEKDRIIDERTKEFEKKLQETLNKSTSSEAEYSKDIETLKKEWLKEYEDETLR------------------------------RIKEAEENLKKRIRLPSE-----ERIQKIISKRKEELEEEFRKKLKEN-----AGSLTFLDNKGSGEDAEEELWNS------PSKGNSERPSAVAGFINQKNLKPQEQLKNVKN----------------DVSFNDSQSMVTNKENNIVDSSAAGNKAIPTFSFGKPFFSSNTSSLQSFQNPFTAS---------------------------------QSNINTNAPLRTLNIQPEVAVKAAINFSN-------VTDLTNNSTDGAKITEIGSTSKRPIESGTSSDPDTKKVKESPANDQASNE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*:.: : . :: : :: .. . ..:: . .: * : : * .: . .: . .: *:: *.:::: :: : . * . . * *: : . :. ::.*..:*: : :. *: . : : . . : . *:.*. :.. : . . * . : :. . : *: : :* : : : *: : : : .:: ::. . : .. : * . * : . :. : : .. . .: :*:. . :* .. : ::: *..:: *:. .:* * .. : :. : :.: . : : : *::.*: :** : . : : : . . : *. : .. * : .::** ::* ** * * : * : : . : :.. : ::.. : : : * *: * : . . : : *. . *: .::: : . . : .: . : .:: :*.. : : : .. . . .: . :: :. * : . ..:::* : . * : * *:: .: *.. : : : . . . : . ::.. .:: : ::.: :: . . * : . : . * . . : ..:.: . : . : : ..: .* : : : : : * *. : . :: : . : .:: . : : : . * . : : : : : . .::. ::: . :* : : : : : : : :. . : . : . . : .*. * * :::: : : .:.: :::.:: :*:*:: ::: : * .. : :.:*: . .. : * . : :: :. :. : :.* :*::. : : : :: . : :: ** : ..: . : . : : : * : * .:. : : :: .:* * . : : . :. : : :::. :: :: ::* : : : :. . : : : .. . : : . ::: : . .... : . . : :. . : :.. . : .. :: :: . :* : : . * . . . . .. * : . .* .:: : : .:.. . . . *. : . : : :.:. :: . :. ::. . .: . . . : :: . .: . . ", "identical_positions": 80, "similar_positions": 541, "identity": "3.18%" }, { "cls_id": "homologset.agr.SGD:S000001412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8C4-1", "uniprot_id": "D3Z8C4_RAT", "id": "D3Z8C4-1", "name": "Protein MCM10 homolog", "aln": "MNVEEDDLCVLTSLLEENEAAAVPCGSEENEKSSSLEEGDPDEFDELFDADGDGESYTEEADSGEEGKTRDQEERLATLFGDVEDLTDD-EVPTSQVEDSSVPPAPVRSREKTNQELQDELKKLQEQMKSLQEQLKAASLQQPPSSAPLHE-PPGASLRPPPQEKKVRRIQESVCFSAELDVPALPRAK-RVARVPKTPAESSSRTSAPSQPLRVISSFLEPKSSPARSTSIPSP--QAVPGNKCSGMTKN----QSKATPGNPGEPSPQVPQVSVEAFSGLRLRRPRVSSTEMNRKMTGRKLIRLSQIKEKMATENLEET---DWVTFGVILRKVTPQSANSGKTFSIWKLNDLRDLTQCVSLFLFG-DVHKDLWKTEQGTVIGLLNANPMKPKEGL-----TEVCLSIDHPQK-VLIMGEAMDLGTCKAK-KKNGEPCTQTVNLHDCEYCQYHIQAQYKKLSAKRSDLQSTFSGGRIPKKFR-RGTSLKERLCQDGFYYGGVSSESFAASMAAAIAPKKKVQTTLTNLVVRGTRSVIQETKQKLGIPQKSLSCSEEFRELMALPTFGARNLQKHLARAKSS---GSPKPAIQSISASALLKQQK---HQMLEMRKRKSEEIQKRFLQSSSEVQSAAVPSSSRQPAAQSPRTGAEFPRLEG--TEAPWTPKLGRGISDGDDVLFFDESPPPKPKLSAAAEAKKLAAISKLRAKGQILTKVDPNNIVRRQMDPRDVLGVKER--AENSNTVS--PEDELEPARKKRREQLAYLESEEFQKILKAKSKHTDVLKEAEAELQKSYFDPLVKKEQMEEKMRAVREVKCRVVTCRKCAYTHFKPLETCVSEQHNLHWHDGVKRFFKCP-CGNRTISLDKLPNKHCRNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VBD2-1", "uniprot_id": "MCM10_MOUSE", "id": "Q0VBD2-1", "name": "Protein MCM10 homolog", "aln": "MDVEEDDLCLLTSLLEENE-AVLPCSSEK-DKSLSLGDGDPDEFDELFDADGDGESYTEEAGSGEEGKTGNQEERLATLFGDVEDLTDD-EVATSKVGNSGPPPAP--SQEKTSEELQDELKKLQEQMKSLQEQLKAASIKQPPGTAPLQE-PPDSSLQPLLKEKRIRRIQESACFSAELDVPTLPKAK-RVARKPKTPAESSSRMRTPAQPLQVSSSFLEPNHSSSSRSSTPSP--QAVPGNKCSRTIRN----QNTVSPGNSGDRPQQVSQVSVEAFSGLRLRRPRVSSTEMSRKMAGRKLIRLPQIKEKMATENLEET---DWVTFGVILRKVTPQSATSGQTFSIWKLNDLHDLTQCVSLFLFG-DVHKDLWKTEQGTVIGLLNANPMKPKDGL-----KEVCLSIDHPQK-VLIMGEAMDLGACKAK-KKNGEPCTQTVNLHDCEYCQYHIQAQYKKLSAKRTDLQSTFSGGRIPKKFR-KGTSLKERLCQDGFYYGGVSSESFAASRAAAIAPKKKVQTTLTNLVVRGTNSIIQETKQKLGIPQKSLSCSEEFRELMALPTFGARNLQKHLARAKAS---GSSKPAIQSISASALLKQQK---QQMLEMRKRRSEDIQKRFLQSSSEVQSPAVPSSSRQAAAQSPRTGAEFPRLEG--TATPRMPKLGRGISEGDDVLFFDDSPPPRPKLSAAAEAKKLAAIAKLRAKGQILTKVDPNNTVRKQMDGRAMLGVKER--VENSNTVS--PEEELEPARKKRREQLAYLESEEFQKILKAKSKHTDILKEAEAELQKSYFEPLVKKEQMEEKMRATREVKCRVVTCRTCTYTHFKPLETCVSEQHNLHWHDGVKRFFKCP-CGNRTISLDKLPNKHCRNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L590-1", "uniprot_id": "MCM10_HUMAN", "id": "Q7L590-1", "name": "Protein MCM10 homolog", "aln": "MDEEEDNLSLLTALLEENE-SALDCNSEE-NNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTK-RVARTPKASPP-------------------DPKSSSSRMTSAPSQPLQTISRNKPSGITRG----QIVGTPGSSGE---TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEI---DWVTFGVILKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFG-EVHKALWKTEQGTVVGILNANPMKPKDGS-----EEVCLSIDHPQK-VLIMGEALDLGTCKAK-KKNGEPCTQTVNLRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKKKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQK---QRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEG--APATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKER--VEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCP-CGNRSISLDRLPNKHCSNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHY1-1", "uniprot_id": "MCM10_DANRE", "id": "Q5RHY1-1", "name": "Protein MCM10 homolog", "aln": "-MTEEENLDMLLSLFAESEGQDLESPAAE--------EGE-DNLDDLFDEDDDGEQYIEPEEAEEE---KEEEEE---------------EVSPGKSSSS--------DLNKSKEDLEAELKLMQEKMQKLQQQLEASQKTTPAQNKPAVQRQSTKSLTSPQAGVKTTPPTVRDSDGSPSNITAKLKNKQRTAHQPKAASS-------------------ERQIPIGQSTNQPQP---MRDGAKVNSMLKSPPLIKTPPTVRQPTPRLPVNQEVAVEKFSGLRLRKPRLSSIDIEQKMASRKLIRLSQLPDRLARDNLEDS---DWVTFAVIINKITPQSKNNGKTFSIWKLNDLHNLEVNVSLFLFG-SVHTDLWKTDTGTVIGILNPNPMKNKEGS-----NELSLTVDHPQK-VLIIGEAMDFGTCKAK-KKNGDSCTQLVNLYECQFCQYHVKAQYKKMSSKRAELQSSFTG-SAPGKGR-GRGSLKERLCQSDFHYGGMSSLACAPSMSAPQP--KKQPTIQSALASIPTKKLVLNSGQVSG-------CSDDFRGLMSMPTPGALNIKRHLGQSKSS---AVAGSSVQSVSASDLLKQQKEQHQQRMMARKKRAEEIQKRVLQSGGAPVASSRPNVSRGP-LLSPKAASEGPKGSGSSLSGPAVPTLGRGFSEGEDIVF-DMSPPSSKSLS----ATKLAAVRKLQAKGSVIVKEDPNAVKRKRANSGDITGRVERNIVKAKVTDENSASEEEEPAMKKRREQLEYIQSEEFQRILNAKSSNSWMMGEIEERAMQEYFEPLVQKEKMEEKMKSIREMKCRAVTCKTCKYTHFKPADRCVEEKHDYHWHDAVKRFFKCP-CGQRKICLARMPHGACSHCGLFKWERDGMLKEKKGPKIGGELLMPRGEEQPKFLNSLK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIE6-1", "uniprot_id": "MCM10_DROME", "id": "Q9VIE6-1", "name": "Protein MCM10 homolog", "aln": "--------------MGPAQKSGTDISIDD--------EEEILALEKLLGAAENENTKSAESEKAKP--------------------TAPILVPKLREDNSFANAFTFEKIVKPEKQKNAAIIKEPELDSSDDEEVKNFLERKYNEYGSDIN----KRLKQQQENAYESKVAREVDQELKKSIHVVTSTP-QPLKNPHNPIK--------------------RQSAVSTTFQRPPP---------------------VAAAVASTSQSSAPVSAVFTDPVFGLRMINPLVSSSLLQERMTGRKPVPFSGVAYHIERGDLAK----DWVIAGALVSKNPVKNTKKGDPYSTWKLSDLRGEVKTISLFLFK-EAHKSLWKTAEGLCLAVLNPTIFERRAGSS----DVACLSIDSSQK-VMILGQSKDLGTCRAT-KKNGDKCTSVVNLTDCDYCIFHVKQEYGKMS-RRSELQSATAGRGINELRN-------KVLGKNEVFYGGQTFTAVPARKSAKLITKERDR--LSMLAGYDVSPFAHTANHTSK---------PKTAEPTKIPYAERGGPVSRLAGGVEA----SRKQRVQDLERLRLLKEEN--------ERFEKKKQAEGHVLGSDNKKESEAGTPAVSMPTTPVP----DKFKNRGFSFDASLTPKLS-----GSENFSFEINVGSRQAQN-----AKLKAAALLKKK--PLEKINPNSTRGSESGKRRAIDELNEK-FSSSAKRQKIDEDDRELMRKSR-----------IEKIMAATSSHTNLVEMREREAQEEYFNKLERKEAMEEKMLTTYKMPCKAVICQVCKYTAFSASDRCKEQKHPLKVVDAEKRFFQCKDCGNRTTTVFKLPKQSCKNCKGSRWQRTAMIREKK-ILTGRETLSVRGDEE-TFMGCLAGSANLNLLVPDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32354-1", "uniprot_id": "MCM10_YEAST", "id": "P32354-1", "name": "Minichromosome maintenance protein 10", "aln": "-------------MNDPREILAVDP------------------YNNITSDEEDEQAIARELEFMER----------------------------------------------KRQALVERLKRKQEFKKPQDPNFEAIEVPQSPTKNRVKVGSHNATQQGTKFEGSNINEVRLSQLQQQPKPPASTTTYFMEKFQNAKKNE---------------------DKQIAKFESMMNAR---------------------VHTFSTDEKKYVPIITNELESFSNLWVKKRYIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPVKFFMFT-ITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWRPSGRGNFIKSFNLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAKRIELNGGYALGAPTKVDS------QPSLYKAKGENG---FNIIKGTRKRLSEEEERLKKSSHNFTNSNSAKAFFD---------------EKFQNPDMLANLDNK-----------------RRKIIETKKSTALSRELG------KIMRRRESSGLEDKSVGERQKMKRTTES-----------------------ALQTGLIQRLGFDPTHGKISQVLKSSVSGSEPKN--------------------------NLLGKKKTVINDLLHYKKE------------------------------------KVILAPSKNEWFKKRSHREEVWQKHFGSKETKETSDGSASDLEII-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: . : : : : : * . : :.: . . . . . : : . .* : . :.. :.. : * : : : :: .: . :*. . : * : .. .. . : :. : . :.:::* . :: * :.:**. : : . * :. * :: :*.: *:* * **. . * . :*: . * :* : :: * :* :*:. : * : * :: :. . :. :: . * :: * .. . : : : . : . *. *. . . . * . :. : *: ..... . . : :* ** : . : ", "identical_positions": 35, "similar_positions": 138, "identity": "3.74%" }, { "cls_id": "homologset.agr.SGD:S000001415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHB2-1", "uniprot_id": "A0ABK0LHB2_RAT", "id": "A0ABK0LHB2-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEETPSATP--TFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETP--PVDQPSRFGN--KAYRTWYAKLDQEAENLVATVIPTNLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSNQLWNIS-AVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGS-LLPIHPVTSG----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58389-1", "uniprot_id": "PTPA_MOUSE", "id": "P58389-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEETPPTTQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETP--PVDQPSRFGN--KAYRTWYAKLDQEAENLVATVVPTHLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSNQLWNIS-AVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGS-LLPIHPVTSG----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15257-1", "uniprot_id": "PTPA_HUMAN", "id": "Q15257-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEEAPPATQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETP--PVDQPSRFGN--KAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNIS-AVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGS-LLPIHPVTSG----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CF49-1", "uniprot_id": "A2CF49_DANRE", "id": "A2CF49-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAETEQASGSSHEDDKPPSSVGFNFMVPKKEISMVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTCEYQV-----------------------------------SETVEKLLALLGTLDQWIDETP--PVDQPSRFGN--KAFRTWYAKLDQEAEALVAGVLPAERQDAAPEIAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKVGALR-MEDQLAIIFNVFDKYLRVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPTLEPRHFVEEKVVNEYHQDYMFLECIKFINEMKTGPFAEHSNQLWNIS-AVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGS-LLSIQPVKP-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40454-1", "uniprot_id": "PTPA1_YEAST", "id": "P40454-1", "name": "Serine/threonine-protein phosphatase 2A activator 1", "aln": "-MSLDRVDWPHATFSTPVKRI----FDTQTTLDFQSSLAIHRIKYHLHKYTTLISHCSDPDPHATASS---------------------------------------IAMVNGLMGVLDKLAHLIDETP--PLPGPRRYGN--LACREWHHKLDERLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVAALDMLGMFP-HMRG-ADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDHFHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINEVKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWFGTGFFPWVNIQNGTDLPVFEEKEEESIEQANAGSPGREQTSTRFPTSTSMPPPGVPPSGNNINYLLSHQNQSHRNQTSFSRDRLRR---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQQ0-1", "uniprot_id": "PTPA_DROME", "id": "Q9VQQ0-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-MASGINQAAGKLPAIAKK------------VQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFES-----------------------------------EMLKKLLRLFDALEKLVEQNP--PLEQPQRFGN--KAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEILQ-ERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIWGSA---QLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLWSIT-DVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGE-LMTFEPVSSGTTLSNARLGHVAPPPSKRICIGTPNLVPPVPVATAPPPPAESLSIEQN-------VGDSSSESSDNS-VVLRPSTSSSSLVAAAE----GSGDKPSKE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNG7-1", "uniprot_id": "Q9VNG7_DROME", "id": "Q9VNG7-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-MEPQSEVNPKRVAAFFRRSN----IGPVCRVQSSSDMEAWLASRAYFTLITYLNDVSAEIQGIRNTDLFPIS-----------------------------------KNIKRLTTIFEQLDSMIVANSPAPLVLGANMDSRTKSYRRWAHGMLRDIYKIVEKAVPSSKCRHVNELGVYLSGSFGSSAKIEYGTGHELSFLFFVCALFKAEILDKEQDLAASALVLFDRYLHFVRRLQVTYSVNSSNWHGGYSLDKFQFVPFVWGFA---QLCHEAPFSPKKMLDEDTIAKYRDAYMLINCVGHMATTNVGTFARHSSQLWSLA-ALSSWTKIHRSLMFMYMEDILMDIDNLNALRFGE-LMSFEEDKSGRHLGSARMG-VKSPLRRQMAEDPDDQDQDQDLTSRSGTPSISRSEQNDSARKKAKVEETSSDCMSNSGLSLGSECTSLSGVSVHLPTWLDDCTATSKNAF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: . : . : :: * :: * : .. *: . .. : * * : . : :* *: ** :.*.:::::****** :* :..* : : : :*::* . *:* ** ::.:. :* :.**.. .: :: * : * .. :.* .:::: : : :. : . : .: : * * .** *:.:: :. *:*: .*: ** : * .: :: . ** ::. ", "identical_positions": 43, "similar_positions": 99, "identity": "9.15%" }, { "cls_id": "homologset.agr.SGD:S000001417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64521-1", "uniprot_id": "GPDM_MOUSE", "id": "Q64521-1", "name": "Glycerol-3-phosphate dehydrogenase, mitochondrial", "aln": "MAFQKAVKGTILVGGGALATVLGLSPFAHYRRKQVSLAYVEAAGYLTEPVNREPPS-REAQLMTLKNTPEFDILVIGGGATGCGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMNLDVEQYRMVKEALHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYDLVAGSQCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPETGKERVSGARCKDVLTGQEFDVRAKCVINASGPFTDSVRKMDDKN------------------------VVPICQPSAGVHIVMPGYYSPENMGLLDPATS-DGRVIFFLPWEKMTIAGTTDTP-TDVTH--HPIPSEEDINFILNEVRNYLSSDVEVRRGDVLAAWSGIRPLVTDP--------KSADTQSISRNHVVDISDSGLITIAGGKWTTYRSMAEDTVDAAVKFHNLN---AGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAKTYGDKA----------FEVAKMASVTGKRWPVVG----VRLVS----EFPYIEAEVKYGIK-EYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWSELRKQEELETATRFLYYEMGYKSRTEQLTDSTEISLLPSDIDRYKKRFHKFDEDEKGFITIVDVQRVLESINVQMD-ENTLHEILCEVDLNKNGQVELHEFLQLMSAVQKG---RVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35571-1", "uniprot_id": "GPDM_RAT", "id": "P35571-1", "name": "Glycerol-3-phosphate dehydrogenase, mitochondrial", "aln": "MAFQKVVKGTILMGGGALATVLGLSQFAHYRRKQVSLAYVEAATCFSEPVNREPPS-REAQLMTLQNTSEFDILVIGGGATGCGCALDAVTRGLKTALVERNDFASGTSSRSTKLIHGGVRYLQKAITNLDVEQYRMVKEALHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYDLVAGSHCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPETGKERVSGARCKDVLTGHEFNVRAKCVINATGPFTDSVRKMDDND------------------------VVPICQPSAGVHIVMPGYYSPENMGLLDPATS-DGRVIFFLPWEKMTIAGTTDSP-TDVTH--HPIPSEDDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDP--------KSANTQSISRNHVVEVSDSGLITIAGGKWTTYRSMAEDTVNKAVKLHNLN---AGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAKTYGDKA----------FDVAKMASVTGKRWPVVG----VRLVS----EFPYIEAEVKYGIK-EYACTAVDMISRRTRLAFLNVQAAEEALPKIVELMGRELNWSELRKQEELETATRFLYYEMGYKSRTEQLTDSTEISLLPPDIDRYKKRFHMFDEDEKGFITIVDVQRVLESINVQMD-EDTLHEILCEVDLNKNGQVELHEFLQLMSAVHTG---RVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43304-1", "uniprot_id": "GPDM_HUMAN", "id": "P43304-1", "name": "Glycerol-3-phosphate dehydrogenase, mitochondrial", "aln": "MAFQKAVKGTILVGGGALATVLGLSQFAHYRRKQMNLAYVKAADCISEPVNREPPS-REAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVRVSGARCKDVLTGQEFDVRAKCVINATGPFTDSVRKMDDKD------------------------AAAICQPSAGVHIVMPGYYSPESMGLLDPATS-DGRVIFFLPWQKMTIAGTTDTP-TDVTH--HPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDP--------KSADTQSISRNHVVDISESGLITIAGGKWTTYRSMAEDTINAAVKTHNLK---AGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAATYGDKA----------FEVAKMASVTGKRWPIVG----VRLVS----EFPYIEAEVKYGIK-EYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDYKKQEQLETARKFLYYEMGYKSRSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESINVQMD-ENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKG---RVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q555-1", "uniprot_id": "F1Q555_DANRE", "id": "F1Q555-1", "name": "Glycerol-3-phosphate dehydrogenase, mitochondrial", "aln": "MAFRKALKG-TLIGGGAVATAVGLSQFFEYRKNQARLAYVEAQGELKVPFKDALPT-REEQLSTLRNTEEFDVLVVGGGATGSGCALDAVTRNLKTALVERSDFSSGTSSRSTKLIHGGVRYLQKAIMKLDYEQYMMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYWAGIKMYDLVAGSQCLKSSYVLSKSKALEFFPMLKKDKLVGAIVYYDGQHNDARMNLAIALTAARHGAAIANYTEVVHLLKKPDPKTGQEKVCGARCRDVVTGQEFDIRAKCVINATGPFTDSLRKMDNQK------------------------TANICQPSAGVHIVIPGYYSPDNMGLLDPATS-DGRVIFFLPWEKMTIAGTTDTP-TEVTA--HPIPMEDDINFILSEVRNYLSPDVEVRRGDVLAAWSGIRPLVTDP--------SSKDTQSICRNHIVNVSDSGLITIAGGKWTTYRSMAEETLDAAIKAHNLS---AGPSRTVGLTLEGGKDWTPTLYIRLVQDYGLENEVAQHLAATYGGRS----------FEVAKMAQVTGKRWPIVG----KRLVS----EFPYIESEVQYAIK-EYACTAIDVISRRTRLGFLNVQAADEALPRIVEIMGKELQWTEQKKKEELEAAKNFLYLEMGYKARSEQLSKTTEISLTPQEVARYKKRFYKFDKESKGFITTVDVQQVLERLSIHID-ENALHEILNEVDLNKNGQVELDEFLQLMSAVQRG---QISDSRLAILLKTAEEGLDLRGPVSVDRSGGGV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32191-1", "uniprot_id": "GPDM_YEAST", "id": "P32191-1", "name": "Glycerol-3-phosphate dehydrogenase, mitochondrial", "aln": "--MFSVTRRRAAGAAAAMATATGTLYWMTSQGDRP-LVHNDPSYMVQFPTAAPPQVSRRDLLDRLAKTHQFDVLIIGGGATGTGCALDAATRGLNVALVEKGDFASGTSSKSTKMIHGGVRYLEKAFWEFSKAQLDLVIEALNERKHLINTAPHLCTVLPILIPIYSTWQVPYIYMGCKFYDFFAGSQNLKKSYLLSKSATVEKAPMLTTDNLKASLVYHDGSFNDSRLNATLAITAVENGATVLNYVEVQKLIK--DPTSG--KVIGAEARDVETNELVRINAKCVVNATGPYSDAILQMDRNPSGLPDSPLNDNSKIKSTFNQIAVMDPKMVIPSIGVHIVLPSFYCPKDMGLLDVRTS-DGRVMFFLPWQGKVLAGTTDIPLKQVPE--NPMPTEADIQDILKELQHYI--EFPVKREDVLSAWAGVRPLVRDPRTIPADGKKGSATQGVVRSHFLFTSDNGLITIAGGKWTTYRQMAEETVDKVVEVGGFHN--LKPCHTRDIKLAGAEEWTQNYVALLAQNYHLSSKMSNYLVQNYGTRSSIICEFFKESMENKLPLSLADKENNVIYSSEENNLVNFDTFRYPFTIGELKYSMQYEYCRTPLDFLLRRTRFAFLDAKEALNAVHATVKVMGDEFNWSEKKRQWELEKTVN--------------------------------------------FIKTFGV-----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z707-1", "uniprot_id": "A1Z707_DROME", "id": "A1Z707-1", "name": "Glycerol-3-phosphate dehydrogenase", "aln": "--MAKIIQMAVMLGSSKLG--HGAFGFDERQADSTPVPQMK----------RELPT-RKMCLEAFKRT-HYDILIIGGGAVGSGCALDAATRGLKTALVEANDFGSGTSSKSSKLLHGGLRDLEQAISRLDVAAFRRVRCSLQERSHIGKLAPHLSQPVPILLPVHHWWQAPLYYMKLKIYHLMAP-KATRSFQYLSADDALEVFPMLRRQELFGAFVFYEGQHDDARMCLSVALTAARYGADICNHMKVSRLIKNKDG-----NVAGAEAVDQLTGKKYSIRAKVVVNATGHMSDSLRQMEDSE------------------------AKPLCTRSWSSIIVMPRFYCPEEVGVFDPHTP-SGRSIFFLPWQGHTLVGSSDEPLNLPEQ--DTQPTETDVQSLLDCVKHFVTPNFDVRRCDVLAVWGGYKPLPVQS---------DTLHHTRFKNHVIQLGPRNMLSIVGGTWSSFRVLAEKTVNAAIRYGDLSPLRKESVTAESCKLDGASGWSPKMFIRLVQDFGMERDVAEHLSNTYGSNA----------FKVAVSADSSGKAWPIVG----KRLHS----EFPYIEAEVKQGVR-DFACTLEDMVARRLRVAFLNVQVAEEILPQVANIMAKELNWSRDQIKKQIRQTRTFLNSQMGQLTKESASQMSIPIKMSVRQVRKFAGQFRQMDDNNTGYVSIADCCKAMKTMGVKEVPVDLMHDVLRDIDVHAQGKVNLYEFLLLMSAIVQGNTEYLRYARLYLDHKRQMQGSNFPTVMQMERAGGGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTA9-1", "uniprot_id": "Q7KTA9_DROME", "id": "Q7KTA9-1", "name": "Glycerol-3-phosphate dehydrogenase", "aln": "--------------------------------------------------MKVVPS--RAEHVNALKAEEFDVLIIGGGAVGCGCAVDAACRGLKTALIEAEDFASGSSSRTSKLIDGSGSYLGTALREKDVEQLYIMLQMMSERVTMLKNAPHLNRIQPMIIPIYSFLQMPCTWLGLKVYDWISAASNIRGSHIISREATMYEFPLLKTDGLRGGVVYYDGQVDDARMCVALVMTAVALGANVGNHMEVVEIMPQEGCCR------VVSVKDKISCEQFYIQSKAVINATGSSTDAIRQMDKEG------------------------TAPILLPTLETQVSLPRYFGSGHYGLLSPALKNDDLTVYMVPFENHMVLGSREVDLDEVSSRGSPTPDPDDVDCLLEAAKKRMDPCVELGRCHVLSAWTAIKASVSCPTD---KENDDDKRGTPINSYMIEVSPDGLITLAGGRWSSYRVMAADAVDLAIKSCGLCDDHVTSSWTQDLKLDGAESWCCMLPLEFVQDYGVPMDVAHHISDSYGYNG------------HALFSQAPDLKKRLHP-------------SFPYIEAEIQYAMRNEYACTLVDIIARRLRIAFVDAAATLHMLPRILKIMAGENGWDEEEQKEQMVAAQEFLVRQMGLGSIVQPRSTSKSKP--------------KKKGSSEGCCCRAAVRRGARSYSMEISKKICVQPLVQHRSMSS-------MFLPLMTSLSYG------LGR---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .:*:*::****.* ***:**. *.*:.**:* **.**:**:::*::.*. * *: . . : : ** : : **** *:::*:: * * : *.*. .: : :* . :: *:* : * ...*:::*. :*:*: ::.:**. ** *: :* :: . . * : . :.:* *:**:* :*:: :*: . : : : :* :: . *::. .. ::::*:: : *: : . * *:: :*. :: : . : * .**:.* . :. . . ..:.: . .::::.** *:::* :* .::: .:. .: . : . * *.. * :.*:: : .::.:: .** .. . .. : :*: .*:: .:: ::. * *.: ** *..*::. : . : ::*. * * . : :: : ", "identical_positions": 94, "similar_positions": 198, "identity": "11.9%" }, { "cls_id": "homologset.agr.SGD:S000001421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZPF4-1", "uniprot_id": "FMNL3_MOUSE", "id": "Q6ZPF4-1", "name": "Formin-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNLES---------TDGGPGEPPS-----------------------------------------VPLLLPPGKTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQER-FQVKNPPHTYIQKLQSFLDPNVTR----------KKFRRRVQEST---------KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSF---------------AQCSVMFDFEGLESGDDGAFDKLRSWSRSIED----LQPPNALSAPFTNSLARSARQSVLRYSTLP--------------GRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNN-KNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCK-----ELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ-----------------------AYLDNVFDVGGLLEDAETKN---------VALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVH-------------------TLRRLIKEKEEAFQRR--------CHLEPSARGLESMGG-EALARVGPTELTEGIPPSDLDLLAPAPP--------------------------------------------------------------------TEETLPLPPPPAP-------PLPP-------PPPPLPDKCPPAPPLPGAAPS-----------------------VVLTVGLSAIRIKKPIKTKFRLPVFNWTALK--PNQING-TVFSELDDEKILEDLDLDRFEELFKTKAQGPAL-------------------------------------------DLICSKNKTAQKAASK-------VTLLEANRAKNLAITLRKAG-RSAEEICRAIHTFDLQT-LPVDFVECLMRFLPTEAEVKLLRQYE-----RERQPLEELAAEDRFMLLFSK--VERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKS-TDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN-------------SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPP-SVFFPVFVRFIRSYKEAEQENE-------------ARKKQEEVMREKQLAQEAKKLDAKTPSQR---NKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKS-VPFT-ARTAKRGSRF----------------------FCD----AAHHDESNC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ART4-1", "uniprot_id": "A0A8I6ART4_RAT", "id": "A0A8I6ART4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNLES---------TDGGPGEPPS-----------------------------------------VPLLLPPGKTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQER-FQVKNPPHTYIQKLQSFLDPNVTR----------KKFRRRVQEST---------KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSF---------------AQCSVMFDFEGLESGDDGAFDKLRSWSRSIED----LQPPNALSAPFTNSLARSARQSVLRYSTLP--------------GRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNN-KNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCK-----ELHRFEKLMEYFRN-EDSNIDFLVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ-----------------------AYLDNVFDVGGLLEDAETKN---------VALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVH-------------------TLRRLIKEKEEAFQRR--------CHLEPSARSLESMGGSEALARVGPTELTEGSTPSDLDLLAPAPP--------------------------------------------------------------------AEETLPLPPPPAP-------PLPP-------PPPPLPDKCPPAPPLPGAAPS-----------------------VVLTVGLSAIRIKKPIKTKFRLPVFNWTALK--PNQING-TVFSELDDEKILEDLDLDKFEELFKTKAQGPAL-------------------------------------------DLICSKNKTAQKAASK-------VTLLEANRAKNLAITLRKAG-RTAEEICRAIHTFDLQT-LPVDFVECLMRFLPTEAEVKLLRQYE-----RERQPLEELAAEDRFMLLFSK--VERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKS-TDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN-------------SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPP-SVFFPVFVRFIRSYKEAEQENE-------------ARKKQEEVMREKQLAQEAKKLDAKTPSQR---NKWQQQELIAELRRRQAKEHRPVYEGKDGAIEDIITVLKS-VPFT-ARTAKRGSRF----------------------FCD----AAHHDESNC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "id": "Q9VUC6-1", "name": "Formin-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAVKSRTITSADVDADEQLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEM-VQAKDPPSHYLSKLRTYLDPKASRSHRLYLFYFLCQKRKMVGESTS-------TQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFR--LQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMGAATDDIHVSIMCLRAIMNNKYGFNMVIQHREAINCIALSLIH-KSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQ-----EKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQIS-----------------------AYLDNVFDVAALMEDSETKT---------SALERVQELEDQL----EREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELT-------------------VMQRMLQHNEQELKKRDTLLHTKNMELQTLSRSLPRSAS-SGDGSLANGGLMAGSTSGAASLTLPPPPPPMPASPT-----------------------------------------------------------ASSAAPPPPPPPAP-------PAPP-------PPPGFSPLGSPSGSLASTAPSPPHAPPMLSSF----QPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALK--PNQVRG-TIFNELDDEKIFKQIDFNEFEERFKIGIGGALR-------------------------------------------NGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLG-MPIDDVIAAIHSLDLKK-LSLENVELLQKMVPTDAEVKSYKEYI-----IERKDQQLLTEEDKFMLQLSR--VERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGP-AYGFKLQSLDTLIDTKS-TDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKG---------AQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADA-AAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSL---QEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKS-EPYRRADAVRRSQRR----------------------RIDNNRLSRTLEEMDC----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BPM0-1", "uniprot_id": "DAAM1_MOUSE", "id": "Q8BPM0-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGG--RGISFIFCCFRNNDHPEITYRLRN------------DSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKK---DQEE-NKGATSWP---EFYIDQLNSMAARKSLLALEKEEEEERS--------KTIESLKTALRTKPMRFVTRFIDLDG--LSCILNFLKT---MDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQS----LSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLH--------YQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG------------------------QDPDSTPLENFNIKNVVRM--------LVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETT-------------------EHKQVKQQVADLTAQLHELNRR--------AVCAAVPGG----PSPGAPGGPFPSSGLGSLLPPPPPPL------------------------------------------------------------------LSGGALPPPPPPLP-------PGGP-------PPPPGPPP-LGGVLPPPGAP-----------------------------VSLTLKKKNIPQPTNALKSFNWSKLP--ENKLDG-TVWTEIDDTKVFKILDLEDLERTFSAYQRQQE--------------------------------------FFVNN-SKQKEADAIDDTLSS--KLKVKELSVIDGRRAQNCNILLSRLK-LSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEH--------KHELDRMAKADRFLFEMSR--INHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRGN-AYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQ---PPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQP-DEFFGIFDQFLQAVAEAKQENE------------NMRKRKEEEERRARLEAQLKE---QRERE-------RKVRKAKE--SSEES----------GEFDDLVSALRSGEVFDKDLSKLKRNRK-----------------RISNQVTDSS-RERPITKLNF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM04-1", "uniprot_id": "A0A8I6GM04_RAT", "id": "A0A8I6GM04-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGG--RGISFIFCCFRNNDHPEITYRLRN------------DSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKK---DQEE-NKGATSWP---EFYIDQLNSMAARKSLLALEKEEEEERS--------KTIESLKTALRTKPMRFVTRFIDLDG--LSCILNFLKT---MDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQS----LSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLH--------YQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG------------------------QDPDSTPLENFNIKNVVRM--------LVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETT-------------------EHKQVKQQVADLTAQLHELNRR--------AVCASVPGG----PSPGAPGGPFPPSGLGSLLPPPPPPL------------------------------------------------------------------LSGGALPPPPPPLP-------PGGP-------PPPPGPPP-LGGILPPPGAP-----------------------------VSLTLKKKNIPQPTNALKSFNWSKLP--ENKLEG-TVWTEIDDTKVFKILDLEDLERTFSAYQRQQE--------------------------------------FFVNNNSKQKEADAIDDALSS--KLKVKELSVIDGRRAQNCNILLSRLK-LSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEH--------KHELDRMAKADRFLFEMSR--INHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSSSEEVLRSSALKQLLEVVLAFGNYMNKGQRGN-AYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQ---PPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQP-DEFFGIFDQFLQAVTEAKQENE------------NMRKRKEEEERRARLEAQLKE---QRERE-------RKMRKAKE--SSEES----------GEFDDLVSALRSGEVFDKDLSKLKRNRK-----------------RISNQVTDSS-RERPITKLNF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U19-1", "uniprot_id": "DAAM2_MOUSE", "id": "Q80U19-1", "name": "Disheveled-associated activator of morphogenesis 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRKRSP--HGLG-FLCCFGGSDLPEIDLR----------------DSHPLQYLEFSGPIPNPEELNVRFAELVDELDLTDKNREAVFALPPEKKWQIYCSKRK---EQEDPNKLATSWP---EYYIDRINAMAAMQNLYETEDEETDKRN--------QVVEDLKTALRTQPMRFVTRFIDLEG--LTCLLNFLRG---MDHTTCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISIIAQS----LRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLH--------YQAYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKHTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERG------------------------VDPDLAPLENFNVKNIVNM--------LINENEVKQWRDQAEKFRKEHMELMSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQ-------------------ELRQARGQVAELVARHNESSTG------------PVSSP----PPPGGP-LTLSSSRTTNDLPPPPPPL------------------------------------------------------------------PFDSCPPPPAPPLP-------PGGP-------PIPPGAPPCFSSGPPPSHDP--FS------------------------SNEAPLRKKRIPQPSHPLKSFNWVKLN--EERVSG-TVWNEIDDSQVFRILDLEDFEKMFSAYQRHQACMQEGPQRERGNVRDGGAASRPLPAVEASAHRTEKASRSMVSATGAKKELGSTEDIYIT--SRKVKELSVIDGRRAQNCIILLSKLK-LSNDEIRQAILRMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEH--------KHEIERMARADRFLYEMSR--IDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELTLSQRLKQMLEVVLAIGNFMNKGQRGG-AYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELKHLSEAAKVNLAELEKEVSILRRGLRAVEVELEYQRHQ---ARDPNDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALTHFGEQESKMQP-DEFFGIFDTFLQAFLEARQDLE------------AMRRRKEEDERRARMEFMLKE---QREKER-----WQRQRKVLAGGALEES----------GEFDDLVSALRSGEVFDKDLSKFKRNRK-----------------RPGSQVPEVT-RERAINRLNY----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B158-1", "uniprot_id": "A0A8I6B158_RAT", "id": "A0A8I6B158-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRKRSP--HGLG-FLCCFGSSDLPEIDLR----------------DSHPLQYLEFSSPIPNPEELNVCFAELVDELDLTDKNREAVFALPPEKKWQIYCSKKK---EQEDPNKLATSWP---EFYIDRINAMATMQNLYDTEDEETDKRS--------QVVEDLKTALRTQPMRFVTRFIELEG--LSCLLNFLRG---MDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISIIAQS----LRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLH--------YQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKHTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERG------------------------VDPDLAPLENFNVKNIVNM--------LINENEVKQWRDQAEKFRKEHMELLSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQ-------------------ELRQARGQVAELTG--------------------PVSSP----PPPGGP-LTLSSSTTTNDLPPPPPPL------------------------------------------------------------------PLDNCTPPPPPPLP-------PGGP-------PIPPGAPPCFSSGSPPPHEP--LS------------------------SNEAPLRKKRIPQPSHPLKSFNWVKLN--EERVSG-TVWNEIDDSQVFRILDLEDFEKMFSAYQRHQ------------------------------------------------KELGSTEDIYLA--SRKVKELSVIDGRRAQNCIILLSKLK-LSNEEIRRAILRMDEQEDLAKDMLEQLLKFIPEKSDVDLLEEH--------KHEIERMARADRFLYEMSR--IDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASQELTLSKRLKKMLEVVLAIGNFMNKGQRGG-AYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELLHLSKAAKVNLAELEKEVGALRRGLRAVEVELEYQRQQ---ARDPNDKFVPVMSDFITVSSFSFSELEEQLNEARDKFAKALAHFGEQDSKMQP-DEFFGIFDTFLQAFLEARQDLE------------AMRRRKEEDERRARMESMLKE---QREKER-----WQRQRKVLVGGALEES----------GEFDDLVSALRSGEVFDKDLNKFKRNRK-----------------RPGNQVAEVT-RERAINRLNY----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58HP70-1", "uniprot_id": "A0AC58HP70_DANRE", "id": "A0AC58HP70-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPRKRTQ--PTLG-ILCCFKSGEPPEINLK----------------DSVPLQLLEFSAPMPPEEELHARFSELVDDLDLTDKNREAMFALPAEKKWQIYCSKKK---EQEDPNKLATSWP---DYYIDRINSMAAMQTLFAFDEAEIEMRN--------KVVEDLKTALRTQPMRFVTRFIELDG--LTCLLTFLRS---MDYETSESRIHTSIIGCIKALMNNSQGRAHVLAHPQSINTISQS----LHQDNIKTKVAVLEILGAVCLVPDGHKKVLQAMAH--------YQKFAAERTRFQSLLNGLDRSTGHYRDEVNLKTAIMSFINAMLNAGVGEESIEFRLHLRYEFLMLGIQPVIEKLRAHDNATLDRHLDFFEMVRNEDELELAKRFDSMHVDTKSAGQMFELIKKKLSHTDAYPHLLSILQHCLKMPYKHDAGSIQQWQLLDRILQQIVLQDENG------------------------ENPDVSPLENFNVRNIIKIYGKRHMSRLVNENEVKQWRDQAEKFRKEHVELMTRLERKDRECETKTQEKEDMMKTLNKMKDKLQREGV-------------------ELRSAKEQVLDMSSRISDISYVGVPLPFPHPLPGSPMPP----PPPSPP-IMLGGSPLLFPPPPPPPPP------------------------------------------------------------------PLLHPPPPPPPPLL-------PPLPPSFAFSSPPPPPPPPSFGCPQPPPGAPPIFSGIP---------------PGPASNSSTTSPQTKSIPQPSQPLKSFNWSKLG--GNEITD-TIWYGIDDRRAFKVLDLKDIEKMFSAYQRQQ------------------------------------------------KETGSMDDLNLS--ARKVKELSVIDGRRAQNCVILLSKLK-MSNEELKRAVLEMDEREELAKDMLEQLLKFVPEKSDMDLLEEH--------KHELERMARADRFLFEMSR--IDHYQQRLQSLFFKKKFADRLAETKPKAEAILCASREVMRSKLLRQVLEVVLAFGNFMNKGQRGN-AYGFKVSSLNKIIDTKSSIDRNITMLHYLIMIFEKNYPDILSIQQDLCSVSEAAKVNLAELEKEVSSIRSGLKALEVELRYQQSR---VCDRGDKFVPVVSDFITVASFSFSELEELLNEAKDKFSMALKHFGEEEGRMQP-DEFFGIFDIFLQSFSEARHDLK------------NMQRCKEEEERKIRLEAMLKD---QRERE-------RRAKKGTKGSVSEEV----------GEFDDLVSALRSGEVFDKD-SKLKRNRK-----------------RSVNQLADAGGRERSVTKMNY----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MSM5-1", "uniprot_id": "M9MSM5_DROME", "id": "M9MSM5-1", "name": "", "aln": "MSSMNQMSVLMDKINTTLQSCPIVCINEPDTHSANTEILQTSPESTLEKPKAAPSGGASTSVTSLNGSCIAINGGIGEGATATASAATSTAAGVTKITITSDNGNGNASTSTKAPTTGSSIDGYKNSSLVSITSLNSCSDLSQGSTATLPISSNSCSGNNVSRHPLSNNNSGSDTSSNNFQERFDFEHWKGLLSDYNCFHGLYRYWTQCSGRSSSANDNGGGSDQQQSQSNHENGLGSEAGSFYTHNILGYTFGYPFGLKEDLDGSGNCNSNCNGSSNTNGLGLRKWLSGNTSSNETPLQKHYRHQQKKKMPGFRGRRVWCGCFKDDEPPEICVVEG---------------AFTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRL--DGHAAFVDALKTALRTSTHSFVLRFVELDG--LPALLDLLLQ---LDIRVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARS----LAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLH--------FQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLLPYT--GHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQ-IDVAKLVRL--------LVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLARMRERLEKESA-------------------QHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTE----GSIPDDQKVAGLTGCNGAVSPPPAP-------------------------------------------------------------------PMLKAIPPPPPPMA-------PSMM---------PPPPPPCPGAPPPPPSMAQTMAP----------------------APPKVDLPKKNVPQPTNPLKSFNWSKLP--DAKLQG-TVWSELDESKLYNNMELESIDKLFSAYQKNGVS----------------------------------------------ATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLK-MSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEH--------SEDIESLARADRFLYEISK--IPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGN-ASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSG--PAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQP-DEFFGIFDSFLAAFAEARHDNE------------SFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGHTSPPRHGSLQREESGRERERTVRRQ----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O60610-1", "uniprot_id": "DIAP1_HUMAN", "id": "O60610-1", "name": "Protein diaphanous homolog 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELER------------FTSMRIKKEKEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEK--QQPLREKDIIIKREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRA----MDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMT------ERAEMDEVERFQPLLDGLKSGT-----TIALKVGCLQLINALITP---AEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADP--------------------DFKCRHLQIEIEGLIDQMIDKTKVE------KSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLE--------AEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLV--AEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKA----------------------------------------------KKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFR-MPYQEIKNVILEVNEAV-LTESMIQNLIKQMPEPEQLKMLSEL--------KDEYDDLAESEQFGVVMGT--VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKS-TDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAA----TDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSV-EEFFMDLHNFRNMFLQAVKENQ-------------KRRETEEKMRRAKLAKEKAEKERLEKQQK-------REQLIDMNAEGDET----------GVMDSLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTILEEAKELVGRAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40450-1", "uniprot_id": "BNR1_YEAST", "id": "P40450-1", "name": "BNI1-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MDSSPNKKTYRYPRRSLSLHARDRVSEARKLEELNLNDGLVAAGLQLVGVALEKQGTGSHIYMKQKNFSANDVSSSPMVSEEVNGSEMDFNPKCMPQDASLVERMFDELLKDGTFFWGAAYKNLQNISLRRKWLLICKIRSSNHWGKKKVTSSTTYSTHLATNELAENAHFLDGLVRNLSTGGMKLS----------KALYKLEKFLRKQSFLQLFLKDEIYLTTLIEKTLPLISKELQFVYLRCFKILMNNPLAR--IRALHSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTG-------CELIWDQLSILFTDWLEWFDKILADDIAIHSSLYLNWNQ-----LKIDYSTTFLLLINSILQGFNNKTALEILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFDSMIKTTNDTN------SLHPTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESIKLLKLINSL-LFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLNAKISHLNEKLNLVENHDKDHLIAKLDESESLISLKTKEIENLKLQLKATKKR---------LDQITTHQRLYDQPPSLASSNLSIAGSIIKNNSHGNIIFQNLAKKQQQQQKISLPKRSTSLLKSKRVTSLSSYLTDANNENESQNESEDKSKDSLFQRSTSTINFNIPSMKNITNMQNVSLNSILSELEFSNSLGTQPNYQSSPVLSSVSSSPKLFPRLSSDSLDNGIQLVPEVVKLPQLPPPPPPPPPPPLPQSLLTEAEAKPD-------------------------------------------------GVSCIAAPAPPPLP-------DLFKTKTCGAVPPPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPN------GLLSSSSVSINPTTTDLKPPPTEKRLKQIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKMKSPTKIAN------------------------------------------KRNAESSIALSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKYEPYSQGKDGKAVSDLQRADRIFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMNKRIVKG----IKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIE-----------KEEMERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREVK----------KDPEPLRRRKSTKLNEIAINVHEGDVK-------------------TRKDEDHVLLERTHAMLNDIQNI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . : : * .. :. : : . . .: . :. : .:. * : : .: : : : : . . :: :. : : . . : .. . : : . . *..* . ..** * . . . * :* : : . . : : *. . :..:. :: * . :. : : . :: : : : . . : ::: : : : : . : . : * : :: : .**.:* :.: * : .:* : ::**:: . .: .: : .:: . . : .: : : : : : : . : : . ** : * : :: . . . . . : :: . . . ", "identical_positions": 23, "similar_positions": 154, "identity": "1.34%" }, { "cls_id": "homologset.agr.SGD:S000001422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21775-1", "uniprot_id": "THIKA_RAT", "id": "P21775-1", "name": "3-ketoacyl-CoA thiolase A, peroxisomal", "aln": "MSESVGRTSAMHRLQVVLGHLAGRPESSSALQAAPCSATFPQASASDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVL----QDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS--LSNRGNPGNISSRLLESDK-ARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDG-GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07871-1", "uniprot_id": "THIKB_RAT", "id": "P07871-1", "name": "3-ketoacyl-CoA thiolase B, peroxisomal", "aln": "----------MHRLQVVLGHLAGRSESSSALQAAPCSAGFPQASASDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVL----QDVKLKPECLGDISVGNVLQPGAGAAMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMT--LSERGNPGNISSRLLENEK-ARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDG-GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921H8-1", "uniprot_id": "THIKA_MOUSE", "id": "Q921H8-1", "name": "3-ketoacyl-CoA thiolase A, peroxisomal", "aln": "----------MHRLQVVLGHLAGRPESSSALQAAPCSARFPQASASDVVVVHGRRTPIGRASRGGFKNTTPDELLSAVLTAVL----QDVRLKPEQLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS--LSGMGNPGNISSRLLESEK-ARDCLTPMGMTSENVAERFGISRQKQDDFALASQQKAASAQSRGCFRAEIVPVTTTVLDDKGDKKTITVSQDEGVRPSTTMQGLAKLKPAFKDG-GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VCH0-1", "uniprot_id": "THIKB_MOUSE", "id": "Q8VCH0-1", "name": "3-ketoacyl-CoA thiolase B, peroxisomal", "aln": "----------MHRLQVVLGHLAGRPESSSALQAAPCSAGFLQASASDVVVVHGRRTPIGRASRGCFKDTTPDELLSAVLTAVL----QDVKLKPEQLGDISVGNVLQPGAGAIMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMT--LSQRGNHGNISSRLLENEK-ARDCLIPMGITSENVAERFGVSRQKQDAFALASQQKAASAQSRGCFHAEIVPVTTTVLNDKGDKKTITVSQDEGVRPSTTMQGLAKLKPAFKDG-GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09110-1", "uniprot_id": "THIK_HUMAN", "id": "P09110-1", "name": "3-ketoacyl-CoA thiolase, peroxisomal", "aln": "----------MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVL----KDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS--LADRGNPGNITSRLMEKEK-ARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27796-1", "uniprot_id": "THIK_YEAST", "id": "P27796-1", "name": "3-ketoacyl-CoA thiolase, peroxisomal", "aln": "---------MSQRLQSIKDHLV---ESAMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIK---LPD----GSICQS-DEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELK---KDQIGVVSMCIGTGMGAAAIFIKE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** : .** :*. : : . ***:* ..*:.* :. :* **:...* ** .:. .: : :. : : ::. ****: **** * * : *.** :.*: ::******** ** .**. *: *. ***:* *****: . * *:*. ::.:: *:.** ***:*.**** .* :**:.** ** * *** *:..* *. **:*:. * :* : *** **..* :.*:.::*** .. *:*****:******.*.:****** *::*.**:** .: .*****::**:******* .*: :** *.*:**********:** **:.** : :**** ***:************** *:*.*** : ***************:* ", "identical_positions": 200, "similar_positions": 112, "identity": "45.25%" }, { "cls_id": "homologset.agr.SGD:S000001428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V7S5-1", "uniprot_id": "PICO_DROME", "id": "Q9V7S5-1", "name": "Putative inorganic phosphate cotransporter", "aln": "-------------------------------------------MPFRRSSLNHR----HRDGHVLVWNQRNLHESLE----------QQPQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDD--------------------SQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYG---FDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREK----------KYINDSLWGTDVVK-----------SPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQYWDNPEDDEQKPALQTTVTTSPARLSNGSTAPAAISSS---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4G7-1", "uniprot_id": "Q9W4G7_DROME", "id": "Q9W4G7-1", "name": "Putative inorganic phosphate cotransporter", "aln": "--------------------------------------MTDTAGVYDSKGVSNR----NRSDQEVRMER---YASDG----------QIP-RCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKER-------------------------------DGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYG---FDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAER----------RHIMEAIWQAQPEE-----------RSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIR-RNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVID--PKPSVENWRIVFYIAAGVFIFTASFYNVFASGKQQW----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYG7-1", "uniprot_id": "Q9VYG7_DROME", "id": "Q9VYG7-1", "name": "", "aln": "-----------------------------MPPHKWTDESRDASCYYDPSTSSNSSASAERSDDEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGS--------------DPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWD-LPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLD---FLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIIN--HRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWS---------------KTPPTRNSRSQRA----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJW8-1", "uniprot_id": "Q9VJW8_DROME", "id": "Q9VJW8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------MADAKEQPEWGIKLS------------KFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTF---------------------EGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSS------MDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEER----------AFLAQEVPPPDKNK------------PKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTP---NATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPFNDGTNSNKKKDAA--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKC9-1", "uniprot_id": "DMGLU_DROME", "id": "Q9VKC9-1", "name": "Dietary and metabolic glutamate transporter", "aln": "-----------------------------------------------------------------MTQQPQWGISLS------------RYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTS-----------------------VGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDA------YGWEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSER----------EYLVKEIGTISRNED----------LPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTP---NASLLEWRLVFWVAFGVLCFTAVIYCIWASGEVQPFNNAPIQPRSVDFEAQERKVGGEKTSGLEQSS--------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5W8I8-1", "uniprot_id": "VGL2A_DANRE", "id": "Q5W8I8-1", "name": "Vesicular glutamate transporter 2.1", "aln": "-----METPRE-PA------GFSKEGLKQLAGKTLGH-VYRVIEKRQKPGE-----NIELTEDGRP---AQINERKAP-------LCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIII---------------------------------KEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQY------TGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEER----------CYIEESIGESAKLLG-------PADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMN-CGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTK---HKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADP---------------ELTSDEKCGFIDEDELAEETGDITQSYG------ALGAPAKSYGATTQLNGG---WAEGWD----KREEYVQ-DGVEEGGYGYRQGGNYS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5W8I7-1", "uniprot_id": "VGL2B_DANRE", "id": "Q5W8I7-1", "name": "Vesicular glutamate transporter 2.2", "aln": "-----MDTVKERVL------APGKEKMRNLAGKTLGH-MHRVMERKQKTGE-----VIELTEDGRP---MHMPEKKAP-------LVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHKGGKIII---------------------------------KGKAKFNWDPETVGMIHGSFFWGYTVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARVHYG-CVMFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGILVQY------SGWSSVFYIYGSFGIVWYMFWILVSYESPADHPTITDEER----------TYIEESIGESAKLLG-------AMEKYKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRSKNILTTTTVRKIMN-CGGFGMEATLLLVVGFSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTK---NKTREEWQNVFLIASLVHYGGVIFYGIFASGEKQPWADP---------------EETSDEKCGFIDEDELAEETGDITLSHAPFGAQGALGAPAKTYGATTQLNGG---WAKGWE----KTEEFIQ-EDAER----TYTGDGYS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANT7-1", "uniprot_id": "A0A8M3ANT7_DANRE", "id": "A0A8M3ANT7-1", "name": "Vesicular glutamate transporter 1", "aln": "-----MEVRPE--------------RFKAVAAKTLGR-INRVLEKRQENGE-----TIELSAEGRP---ELQEEKELP-------VVDCTCFGLPRRYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYRDGKPYI---------------------------------V-KAQFSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARMHFG-CVILVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLVQY------SGWSSVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEER----------KYIEDAIGESAGLVN-------PLTKFNTPWRQFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLADYLRTHNLMTTTNVRKLMN-CGGFGLEATFLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTK---NKTREEWQYVFLIASLVHYGGVIFYGLFASGEKQPWAEP---------------ENTSEEKCGILGEDELADETEELYRSAG--GGYGATMQSGDPNGAGTGGGGAGGSWVSDWD----KTEEYVQPVGTNSFLYGGEEGRGMNE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X9-1", "uniprot_id": "VGLU3_DANRE", "id": "Q1L8X9-1", "name": "Vesicular glutamate transporter 3", "aln": "MPLGGFAGLKEKLN-------PGKEELKNNVGDSLGN-LQKKIDGSNVTEED----NIELTEDGRP---VAAPKRSPP-------LLDCGCFGLPKRYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVM---------------------------------Q-PAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYG-CVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQY------VGWPSVFYIYGVFGIIWYIFWILLAYNSPAVHPTISEEER----------NYIETSIGEGANLMS-------STEKFKTPWREFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTTTVRKIMN-CGGFGMEATLLLVVGFSHTRAVAISFLILAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGALTK---HKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDWADP---------------ENTSDEKCGIIGEDELADETEPSSDSG--------LATRQKTYGTTDNSSGR----KQGWK----KKRGVTMQAEDDHESNHYENGEYQTQYQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQC0-1", "uniprot_id": "Q9VQC0_DROME", "id": "Q9VQC0-1", "name": "", "aln": "--MKGLTAFKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMN---------------------------------------------WTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADA------VGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPEL----------KYIEKSLGESAHPTM-------PSLKT-TPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFN-CGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQ---ANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYMKETSFGAPEYTEQ----SQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYGDVTNPGQYGYTQGQMPSYDPQGYQQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VR44-1", "uniprot_id": "Q9VR44_DROME", "id": "Q9VR44-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------------------------------------------------------MSNTEKG-------GLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDG-----------------VDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHINYV-VLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAITMPICGYLISV------AGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEER----------REIEEAIGTTTSKKR----------PSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYK--DQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPP--------------ERVRISDVTQEEGVPLKNEK-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPX2-1", "uniprot_id": "Q9VPX2_DROME", "id": "Q9VPX2-1", "name": "", "aln": "-------------------------------------------MTDEVPAKG-----------------------------------SILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAINVVCTLLTPVFTELHYG-GLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGTALSILLAGVCSAQ------WGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEER----------QMITSSLGTEQKTEH----------HPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKG--NQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAG-------------TPKDPEAKDEKTPLKELPTKP-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40445-1", "uniprot_id": "YIQ6_YEAST", "id": "P40445-1", "name": "Uncharacterized transporter YIL166C", "aln": "--------------------------------MSVQKEEYDIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRK-------VYESSGYEGLSKFDPEFTWTKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDN----------------------------FIVDLKMNTNDYNLGQTVYLVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRG---QFIATRCLLGMVQGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGD-------MSNRQPVTFKEILYTLTEFDLWPLFIQG-ITAFISLQTVGSYLSLILKS-LNYSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTG-ILGLPYTHSILAGWVS-EISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGFTCFNICMAVATKFYYISRNKYKDRKWNSMTK-----------EEQINYLDTTKDKGMKRLDYRFIH-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : :.:* : . : : . . * : *. * * : . * : . :.. .: * . .. . * : : : .: . . . : : : :: : : . : . . : : . . .* : : . .: * . . ..: . . . : . . : ", "identical_positions": 10, "similar_positions": 71, "identity": "1.41%" }, { "cls_id": "homologset.agr.SGD:S000001434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVIS-------PKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGK-YTDYYIWHNCTHVN--GVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IITFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTHYSELYHDFTTTQVGMHDIVRDFRQTMNQYSREP--GRYRFMGAEASAESIERTMMYYGLPFIQEADFPFNKYFTTIGTLSG----------HTVYEVITSWMENMP-EGKWPNWMTGGPETPRLTSRVGSEY-------VNAMHMLLFTLPGTPITYYGEEIGMGDIS-----------------VTNFNESYDSTTLVS-------------KSPMQWD-NSSNAGFT-EANHTWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHAT---ELVLSRGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASK--GS-AVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIIS-------PKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGK-YTDYYIWHNCTHAN--GVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IIKFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTRYSELYHDFTTTQVGMHDLVRDFRQTMNQFSREP--GRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFNKYLATLDTLSG----------HTVYEAITSWMENMP-EGKWPNWMIGGPETSRLTSRVGSEY-------VNAMNMLLFTLPGTPITYYGEEIGMGDIS-----------------ITNLNERYDTNALLS-------------KSPMQWD-NSSNAGFT-EANHTWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHAR---ELLLSRGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASK--GS-DVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALS-------PKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSRTRTGK-YTDYYIWHDCTHEN--GKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKE-ILRFWLTKGVDGFSLDAVKFLLEAKH-----LRDEIQVNKTQIPDTVTQYSELYHDFTTTQVGMHDIVRSFRQTMDQYSTEP--GRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFNNYLSMLDTVSG----------NSVYEVITSWMENMP-EGKWPNWMIGGPDSSRLTSRLGNQY-------VNVMNMLLFTLPGTPITYYGEEIGMGNIV-----------------AANLNESYDINTLRS-------------KSPMQWD-NSSNAGFS-EASNTWLPTNSDYHT-VNVDVQKTQPRSALKLYQDLSLLHAN---ELLLNRGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADK--GS-KVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7F2-1", "uniprot_id": "A1Z7F2_DROME", "id": "A1Z7F2-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MQGTRLDHFGLLVCGLVILAHPSWSCET-----TTSTTVTKDWWENAQFYQIYPRSFMDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKSVNREKG-YEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQQYYLHQFAVQQADLNYRNPLVVEQMKR-VLRYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTD---DVDDRKYLKSDLIENRPETIDMAYQWRVVMDDYQRIH-GGETRVLLIETYAPPAYTMQFYGNRS-TAGAHLPFNFNLITVLASD-------GVSAGSIKTAVDNWLDNLP-AGRTANWVIGNHDQRRAASRYGTAN-------ADAMNMLVMVLPGASVTYQGEELGMTDG------------------EISWEDTQDPAACNSNSDIYEQFTRDPSRTPFQWT-NGTNAGFS-TASKTWLPLAADYQT-LNVETEAAAQRSHLKIYKALVELRKSS---LPLQNGSTKYGVVGENVFVVKRYISGSA-SIIYVANFASKGVTVDLYEFDKTLPTHLTLLIRSLQSSKAEGS-QFEVTGLSLAAGEALVLSSSSSSRFD----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F3-1", "uniprot_id": "A1Z7F3_DROME", "id": "A1Z7F3-1", "name": "alpha-glucosidase", "aln": "--------------------------------------------------------------------------------------MELLSLLTLLLLAIASNEACQVQ-----SSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVDFGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVKREKG-YEDYYVWHDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKR-VLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATE---DKEDRDYLTTTYIENQPETIDMVYQWRTVLDDHKRIF-GGNSSVLLIETYSPAWFTMQFYGNRS-TEGAHLPFNFNLITVMEQS-------GLSASNVQEAIDLWLKNMP-AGRTPNWVLGNHDKRRAASRYGKEN-------IDGMNMLVMILPGVSVTYQGEEIGMTDG------------------EISWEDTVDPWGCNSNPNIYEQYTRDPERTPFQWT-GGTNAGFT-NGSSTWLPLAADYAT-INVEKELSDDHSHLKIYKALVALRKSS---KTLQNGSTKYQALSEDIFVVQRSLTKSA-TIVLVINFGSVAKTVDLSQFDKSRTESLQLLIRSIDSTKKEGT-RYDPKALSLDPSEALVLTTE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F1-1", "uniprot_id": "A1Z7F1_DROME", "id": "A1Z7F1-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MACFKVLIAAILVLGIHCALGSAAAVDLDLERATTAADTTRDWWQVAQFYQIYPRSYKDSDGDGIGDLQGIISKLDYLKEIGVTATWLSPIYSSPMADFGYDISDFFDIQPEYGTLADFDELIAEAKKRNIKIILDFVPNHSSDENVWFQKSVKREKG-YEDYYMWHDGYVNATTGKREPPSNWLQAFRGSAWEWNDERQQYYLHQFAVKQPDLNYRNPAVVAQMKR-VLTYWLDRGVAGFRMDAVPWCFEVLPDADGRYPDEPLSGYTD---DPDDSSYLKHIYTQDLRETVEMVFQWRTLLDDYQRIH-GGDTRVIMVETYSGLDYVMQFYGNRT-TKGAQMPFNFQFIIGGNGDKNNT---QLNATGFVKIISSWLSQMP-AGQTANWVMGNHDQRRVGSRYGENR-------IDLMNMLQMFLPGVSITYQGEELGMTDL------------------DISWEDSRDPAACNSNSDIYEQFTRDPARTPFQWS-DEANAGFS-TNATTWLPINPNYVT-VNAKAENSTSPSHLSLYKQLVDLRKS----KTLQFGATRYANVGDNVVAIRRYLSGEP-SYVLVANVLDTSVSGIDVASAIYATGSYKIKLLNPQAKATVGD-SVTLSNLTLEPYAALILESV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07190-1", "uniprot_id": "MAL1_DROME", "id": "P07190-1", "name": "Maltase A1", "aln": "------------------------------------------------------------------------------------MRPQSAACLLLAIVGFVG------------------ATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVDSDPV-YKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKN-VIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVEN-GGDKRLLMTEAYTSFENIMTYYGNGV-RNGSHIPFNFDFLTSINNAS--------KAGEYVEHIKKWMDAMP-EGVYANWVLGNHDNKRVASRFGVQR-------TDLINILLQTLPGHAVTYNGEELGMTDV------------------WISWEDTVDPNACNSDPDNYYARSRDPARSPYQWD-ASSKAGFT-SADHTWLPVADDYKT-NNALQQLRAPRSHLQIFKKLVRVRKE----PSFRQGELNIQAIDDDVIIYSRQKTGSD-LYVIVLNLGSTSKTLDLTKYYELG-TQAEVITTSLSSQYIDGD-VIKSTEFVANPYVGTVLVAV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07192-1", "uniprot_id": "MAL3_DROME", "id": "P07192-1", "name": "Maltase A3", "aln": "----------------------------------------------------------------------------------MFKLLVLSCLLALALPSLAEVG-------------------WWKTGQFYQIYPRSFKDSDGDGVGDLIGITQQLPYLKEIGITATWLSPIFTSPMADFGYDVADLKGIDPIFGTMEDFEALLARAKELDIKIILDFVPNHTSDECDWFIRSAAGEEE-YKDFYVWHTGKVVN--GIRQPPTNWVSVFRGSMWTWNEQRQAYYLHQFHAKQPDLNYRNPKVVEAMKD-VLRFWLRKGAYGFRIDAVPHVYEIPADADGNWPDEPRNEAVS---DPEDYTYLQHIYTTDQPETLELVYAFRDVIEEIDAEL-GGDDRVLLTEAYSPLEVLMQYYGNGT-HLGSQIPFNFELLAKISYSS--------DAYHYSELIHNWLDNMP-EGQVANWVFGNHDQSRIGSRLGADR-------IDACNMIILGLPGVSVTYQGEEMGMTDV------------------WISWEDTVDPQACQSNEQEFERLTRDPVRTPFQWS-DEVNAGFS-NASVTWLPVASNYKL-VNVKKERGIALSHLNVYKQLRALRDE----PTLKQGDVSVTAIGPNVLAFKRSLAGYK-SYITLININDDVESINLDSVFTSITTQLQYVVVNDKSVRRKND-LTFANSVLLLPKEAVVLSTV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7E8-1", "uniprot_id": "A1Z7E8_DROME", "id": "A1Z7E8-1", "name": "alpha-glucosidase", "aln": "----------------------------------------------------------------------------------MTTWTSLFLLLGLGLLAVDAAAP------------------WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAAGEEE-YKDYYMWHPGFLDED-GTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRNPVVREEMNN-VLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTN---DPDEYGYTHKIYTVDQPETPHLVYEWRQILEQFQADN-GGDERILMVETWSPIEIVMHYYGNET-ADGAQIPFNFQLISNLHYDS--------DAYHYEYLINNWLNLMP-EGKSANWVIGNHDKNRVGSRFGADR-------VDLFNILLLTLPGCSITYQGEELGMLDG------------------YVSWEDTVDPQACNGYEANYMDNSRDPARTPMHWS-DETMAGFT-TGNSTWLPVSTDYRQ-RNVKTERGVSLSHLNVFKRLQQLRQE----PSIEEGSAEVKAVSNYVLAVKRHLSGDF-VYISLFNIFDSIENVNLSSVFGSLPAKFQYALVTEKSIKKVGD-QVSAGSVTLMPHESIVLRSTTTA-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07191-1", "uniprot_id": "MAL2_DROME", "id": "P07191-1", "name": "Maltase A2", "aln": "----------------------------------------------------------------------------------MPKWAHLGLAALLLISTTQEGTAD---------------IDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVNREDG-YDDFYVWDDGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLD-VLKFWLDRGVDGFRIDAVPHIYEHRN-ADGSYPDEPVSGWGS---DPNAYDYHDHIYTKDQPATVDLMYEWREFLDNYRAQN-GGDSRVLLAEAYSSVETLSAYFGNST-HQGTQLPMNFQLMYLSGYS---------TAKDVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHK-------VDLLNVIVNALPGASVTYYGEEIGMSNV------------------DVECTG----DSCE---------DRDGERTPMQWT-AGKNADFS-DGESTWLPLSPEYQR-YNVQTERGVSRSSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRTNKISE-EYRILVNMGNGMEILD-----GLAPKTYEYVLATAYSTHYSGQKADLSQRIILMPYEAVVLRWLA---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKE6-1", "uniprot_id": "Q9VKE6_DROME", "id": "Q9VKE6-1", "name": "alpha-glucosidase", "aln": "-----------------------------------------------------------------------------------MVVVKIAFILSVGLVGILAHKHQSK--------ELDAKYNWWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRLQYFKDTGITSVWLSPIYESPMVDFGYDISNYTNIQPEYGTLEDFDALIAKANELGVKVILDFVPNHSSNKHPWFIKSVAREPG-YEDFYVWEDG-ILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQFTYGQPDLNYRNPAVIKAMDD-VMLFWLNKGIAGFRIDAIIYIYEDAQ-----LRDEPPSGTTD---DPNNEAYLSHIYTRNQPEDYGLLQHWRQLLDNYTANH-DGPLRIMMTEGYASVSQLMEYYEDSNGVQGPQFPFNFDFITELNANS--------TAADFVFYISRWLIYMP-HGHVANWVMGNHDNPRVASRFGEKS-------VDAMNMLLMTLPGIGITYNGEELGMTDYR-----------------DISWSDTVDQPACEAGIDNYKTISRDPERTPMQWS-SDVNAGFS-SADRTWLPVNPNYKE-LNLRNQQQARRSHYKIYQSLLKLRQL----PVLKNGSFVPEVVNRRVFAFKRELKNEH-TLLTIVNVSNRTELVDIADFIEQP-NRLSVLVAGVDSQHRVGD-RLKAETIELAPNEGLVIQLNKRK-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A4P1SA55-1", "uniprot_id": "A0A4P1SA55_DROME", "id": "A0A4P1SA55-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MRAPLIQILLFSLLNSGSIMAGLVKS---------DTEDFIDWWPHTVFYQIYPRSFKDSNGDGIGDLKGITSKLRYLADTGITATWLSPIFQSPMIDFGYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSSDQHEWFKKSAAREPG-YEDFYVWHDG-IVQENGTRVPPNNWPSVFYGSAWEWHEGREQYYLHQFTKEQPDLNYRNPKVVQAMDD-VLLFWLNKGVAGFRIDAVNHLFEDES-----LKDEPLSGKTT---DSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDFSAKHPERPTRIMMTEAYAGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGDS--------DARDYVYNVEKWLIYMP-RGHAANWVMGNHDNPRVASRFGPAS-------VDAMNMLLLTLPGVAVTYNGEELGMVDYR-----------------ELSWEETVDPPARNVGEKLYQEVSRDPVRTPFQWN-NETNAGFS-TAAKTWLPVHPNYLE-LNLEAQKVANRSHYQVYKDLLELRKS----AIMRVGRFNIEPLTRWVFAFKRSYPNFE-SIITVINVSDKEQLVDLSEFLSQP-KKLVVEVSGVDSKYQPGQ-SLAASALLLAAREGLVCRLV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CW40-1", "uniprot_id": "MALX2_YEAST", "id": "P0CW40-1", "name": "Oligo-1,6-glucosidase IMA3", "aln": "-------------------------------------------------------------------------------------------MTISSAHPETEP-------------------KWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAG-----LPDAPVIDENS-------KWQLSDPFTMNGPR----IHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKT--LFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRS----------EVDASSRTLKPWEGRIYISE----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***** *: **: :* **: *: .:* *: . *::.: *. *: * : : : * :** * :: . .:*.: *:: ** * : ** * *::.* * **.** . : . * :.: : ::: * *.*:*: * : : :** * ** *. : : :: ::. .: :* : : : .. . : * * * . :: *.* .* *:*:* : . ::* :* *.*: .*: .: * : * .:: .: . . : *. . . : ", "identical_positions": 69, "similar_positions": 98, "identity": "9.07%" }, { "cls_id": "homologset.agr.SGD:S000001435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW09-1", "uniprot_id": "D3ZW09_RAT", "id": "D3ZW09-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "------------------MAHRGTPSAPKRPGLTAPDRSSQVLLPPCWPRSWP-----LLLLLLVLVAACGAMGRSPQPGRWGPSVQVTRLL---PAGRTESSNRQDPQTRESEPGVPGL-----------------------------RPGSASGPSTDGAPALGKGRR---------------------------VRAAPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKY-YHADMGKVLES-SLWRSSDFGTTYTKLTLQPGV------TTVIDNFYICPANKRKIILVSSSLGDREQSLFLS------TDEGTTFQKYPVPFL-VETLLFHPKEEDKVLAYTK-----DSKLYVSSDLGKKWTLLQEQVTKDHVFWAVSGVDDDPNLVHMEARDLSGGYRYYTCLIHNCSAQPHTAPFPGPTDRGS----LTVQDEYIFLKATSTNRTKYYVSYRR-SDFVLMKLPKYALPKLFCPQDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSS-----------RQAEENVVIDILEVRGVKGVFLANQKV----DGKVTTVITYNKGRDWDYLRPPSTDMNGKP-TNCQPPD-CHLHLHLRWADNP---YVSGTVHTKDTAPGLIMGAGNLG--SQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDT----SIPLKTLKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFPRP-CVEDDYSSWDLTDL----QGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRV--CKCRDSDFLCDYGFERSSSSESTVNKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGG-VDLQQSPVQLQCPLQA-------------------------------------------------------------------------------------------------------------------------PRGLQVSIRGEAVAVRPREDVLFVVRQEQGD--------------------------------------VLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAEN----------------------MAGH-----------------------------DEAVLFVQVNSPLQALYLEVVPVIGINQEVNLTAVLLPLNPNLTVFYWWIGHS--------------------------------------------------------------------------------------------------------------------------------LQPLLSLDNSVTTRFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLQFSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLDTFNPN--TPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPPPRPTRKRSLTS---DKRLAAVQQALNSHRISFILRGGLRVLVELRDTDAGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ--EMTSPVSHSEDAQSAMQG--------------------------------------------NHSGVVLSINSREMHSYLVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPR5-1", "uniprot_id": "SORC2_MOUSE", "id": "Q9EPR5-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "------------------MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWP-----LLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLL---PAGRTESGDRKDPQARESEPSVPGL-----------------------------GPGSASGPSTDGAPAPGKGRR---------------------------ARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKY-YHADMGKVLES-SLWRSSDFGTTYTKLTLQPGV------TTVIDNFYICPANKRKIILVSSSLGDREQSLFLS------TDEGATFQKYPVPFL-VEMLLFHPKEEDKVLAYTK-----DSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGS----LTVQDEYIFLKATSTNRTKYYVSYRR-SDFVLMKLPKYALP-----KDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSS-----------RQAEENVVIDILEVRGVKGVFLANQKV----DGKVTTVITYNKGRDWDYLRPPSTDMNGKP-TNCQPPD-CYLHLHLRWADNP---YVSGTVHTKDTAPGLIMGAGNLG--SQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDT----SIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFPRQ-CGEDDYSSWDLTDL----QGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRV--CKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGG-VDLQQSPVQLQCPLQA-------------------------------------------------------------------------------------------------------------------------PRGLQVSIRGEAVAVRPREDVLFVVRQEQGD--------------------------------------VLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAEN----------------------MAGH-----------------------------DEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHS--------------------------------------------------------------------------------------------------------------------------------LQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELDTFNPN--TPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTS---DKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ--EMTSPVSHSEDAQSTMQG--------------------------------------------NHSGVVLSINSREMHSYLVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PQ0-1", "uniprot_id": "SORC2_HUMAN", "id": "Q96PQ0-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "------------------MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRP-----LLLLLLLLG-ACGAAGRSPEPGRLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGP-----------------------------SPGPAPGPGEDGAPAAGYRRW---------------------------ERAAPLAGVAS--RAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKY-YHADMGKVLES-SLWRSSDFGTSYTKLTLQPGV------TTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLS------ADEGATFQKQPIPFF-VETLIFHPKEEDKVLAYTK-----ESKLYVSSDLGKKWTLLQERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGS----LTVQDDYIFFKATSANQTKYYVSYRR-NEFVLMKLPKYALP-----KDLQIISTDESQVFVAVQEWYQMDTYNLYQSDPRGVRYALVLQDVRSS-----------RQAEESVLIDILEVRGVKGVFLANQKI----DGKVMTLITYNKGRDWDYLRPPSMDMNGKP-TNCKPPD-CHLHLHLRWADNP---YVSGTVHTKDTAPGLIMGAGNLG--SQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDT----SIPLKILKFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFSRQ-CGEEDYSSWELSNL----QGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRV--CECRDSDFLCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGG-VDMQQSQVQLQCPLTP-------------------------------------------------------------------------------------------------------------------------PRGLQVSIQGEAVAVRPGEDVLFVVRQEQGD--------------------------------------VLTTKYQVDLGDGFKAMYVNLTLTGEPIRHRYESPGIYRVSVRAEN----------------------TAGH-----------------------------DEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLNPNLTVFYWWIGHS--------------------------------------------------------------------------------------------------------------------------------LQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQVMPLQFSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELDAYNPN--TPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVLLPPPRPTRKRSLSS---DKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQ-----------------------LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ--EMTSPVSHSEDVQGAVQG--------------------------------------------NHSGVVLSINSREMHSYLVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5D7-1", "uniprot_id": "A0AC58G5D7_DANRE", "id": "A0AC58G5D7-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-------------------------------MKTLIMAVFAHLYPAVFFACAW-----MALLGPISCHSSGIIKQRSERDR-------------------ELDSRGGHVTGTDEALISAY-----------------------------SRGDYSG--DPGGAAVGVPRV---------------------------RRAS--------TPEKVSLLSSSFVLKGDATHNQAMVHWTGENSSVILILTKY-YHADSNKVLES-SLWRSSDYGSTYTKLNLMPGT------TIIVTNFYICPTNKKKVILVSSSINERDQMLFIS------TDEGASFQRQPVSFT-VDSLLFHPSEEDKLLAYSK-----EAKLYISTDLGHKWTLLQERVTKDRVFWAVTGVDVDPDLVHMEMQDISGGYLYVTCLIQNCSDKMVTAQFLGKIDHNS----LSVQDEYIFVKVTTGNRTKYYVSYRR-NEFVQMRFPKYSLP-----KDVQIVSTDENQVFLALQEWYQTDTYNLYQSDPQGVYYSIVLENVRST-----------KQPEENVLIDILEVRGVKGVFLANQKV----DGKVMTLITYNKGRDWEALAPPATDMNGKP-VSCKQPD-CHLHLHLRWADNP---YVSGTVHTKDSAPGLIMGAGNLG--SQLVEYKEEMYITADCGKTWRQVFEEEHHILYLDHGGVIVAIKDT----SIPLKILKFSIDEGRTWSIHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISYRSDWELVKVDFRQSFPRQ-CTEADYDSWKLTDL----QGEKCIMGQERVYRRRKETSFCIKGKSYTSALTAKP--CPCSEKDFTCDYGFERAPSLRLEGDRCYPDFWHNPDAPPENCHLGHSYKSSTGYRKVIANVCEGG-LNKEQSAKQHSCPLLP-------------------------------------------------------------------------------------------------------------------------PKGLQLGIKGQMLAVAPGDDITFIVHQEQGD--------------------------------------TSSTRYQVDLMDGVRAIYENLTVTDEPIQHRYEKPGVYRVNVKAEN----------------------SAGH-----------------------------DQAMLYIQVTAPLQDVHLEVVPIAGRNQDVNLTAIVLPTEANLTVFYWWIGDN--------------------------------------------------------------------------------------------------------------------------------MQPKLTLENSLITRFSEEGEVPVTVQASNGRSMVQDSKTVIVYDHFQIIPLSFSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDHFNPN--IPEWRRDVGEVVTKIIAKLTGVPQEHLVTMLKPGLPTSADLYVLPQETTP-VKRSVFV---DKRVPTIKQVLSENNVSFIVRGGLRVLVTLADLDSGPITSDVSVSTTETATQLTSSTQGSGLAAAGPGVWAVAVFLLISLISAAAFILFKFKRKNYKNHGWLLRPEESSLTRPWLRFRKLPGRNVYAQMHNEKEQ--EMTSPVNHSEDTQNIIQGE------------------------------EFIDDDLDSQTLGNHSGVVLSINSRELHSYLTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JLC4-1", "uniprot_id": "SORC1_MOUSE", "id": "Q9JLC4-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-----MGK-VGAGDGSSAGLSALLAGAGLLMLLAPGVCSSLSCCPPQHPSSTP-----RRTLTPRGFPHPGPLGRAPAT-PPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATAARSGR-----RRRSGTEPEKIE-----------PGEGASR--SRRDMLKDGGQ-----QGLGTG-----------------ARDPGKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKL-YDYNLGSITES-SLWRSTDYGTTYEKLNDKVGL------KTILSYLYVCPTNKCKIMLLTD--PEIESSLLIS------SDEGATYQKYRLNFY-LQSLLFHPKQEDWILAYSQ-----DQKLYSSAEFGRRWQLIQESVVPNRFYWSVMGSSKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDS----LIVQDDYVFVQLTSGGRPHYYVSYRR-SPFAQMKLPKYALP-----KDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVRSS-----------RGPEGNVMIDLYEVAGIKGMFLANKKI----DNQVKTFITYNKGRDWRLLQAPDADLRGDP-VHCLLPY-CSLHLHLKVSENP---YTSGIIASRDTAPSIIVASGNIG--SELSDSDISMFVSSDAGNTWRQIFEEEHSILYLDQGGVLVAMKHT----SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRR-CAEEDYRPWQLHS-----QGEACIMGAKRIYKKRKSERKCMQ--KYAGAMESEP--CVCTEADFDCDYGYERHSN-----GQCLPAFWFNPSSLSKDCSLGQSYLNSAGYRKVVSNNCTDG-VREQYTAKPQKCPGKA-------------------------------------------------------------------------------------------------------------------------PRGLRIVTADGKLTAEQGHNVTLMVQLEEGD--------------------------------------VQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDN----------------------SLGS-----------------------------DSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN--------------------------------------------------------------------------------------------------------------------------------TEPLITLEGSISFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLAFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDDYNPD--IPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGTRENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVD----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRR-------------------------VA-----------------LPSPPSPS-AQPGDSSLRLQRPR------------------------PATPPSSPKRGS---AGAQFAI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEA1-1", "uniprot_id": "A0A8I6AEA1_RAT", "id": "A0A8I6AEA1-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-----MGK-VGAGDGSSAALSALLTGAGLLMLLAPGICSSLSCCPPQHPSSTP-----RWTLTPRGFSYPGPLGRAPAT-PPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATASRSGR-----RRRSGMDPEKTE-----------PGEGTSR--SRRDMLRDGGQ-----QGPGTG-----------------ARDPDKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKL-YDYNLGSITES-SLWRSTDYGTTYEKLNDKVGL------KTILSYLYVCPTNKRKIMLLTD--PEIESSLLIS------SDEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQ-----DQKLYSSAEFGRRWQLIQEAVVPNRFYWSVLGSNKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDS----LIVQDDYVFVQLTSGGRPHYYVSYRR-NPFAQMKLPKYALP-----KDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSS-----------RGPEGNVMIDLYEVAGIKGMFLANKKI----DNQVKTFITYNKGRDWRLLQAPDADLRGDP-VHCLLPY-CSLHLHLKVSENP---YTSGIIASRDTAPSIIVASGNIG--SELSDSDISMFVSSDAGNTWRQIFEEEHSILYLDQGGVLVAMKHT----SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRR-CAEEDYRPWQLHS-----QGEACIMGAKRIYKKRKSERKCMQG-TYAGAMESEP--CVCTEADFDCDYGYERHSS-----GQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG-VREQYTAKPQKCPGKA-------------------------------------------------------------------------------------------------------------------------PRGLRIVTADGKLTAEQGHNVTLMVQLEEGD--------------------------------------VQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDN----------------------SLGS-----------------------------DSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN--------------------------------------------------------------------------------------------------------------------------------TEPLITLEGSISFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLAFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDDYNPD--IPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGARENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVD----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRK-------------------------IPGINVYAQMQNEKEQ--ELINPVSHTESRPTAPHPDLRRPGQLVDEKVESHLL------------DQDKPHHLHRQSGDLLGHNLQSKENPQRLQETC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WY21-1", "uniprot_id": "SORC1_HUMAN", "id": "Q8WY21-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-----MGK-VGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAP-----RSASTPRGFSHQGRPGRAPAT-PLPLVVRPLFSVAP-GDRALSLERARGTGASMAVAARSGR-----RRRSGADQEKAE-----------RGEGASR--SPRGVLRDGGQ-----QEPGTR-----------------ERDPDKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKL-YDYNLGSITES-SLWRSTDYGTTYEKLNDKVGL------KTILSYLYVCPTNKRKIMLLTD--PEIESSLLIS------SDEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQ-----DQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDS----LIVQDHYVFVQLTSGGRPHYYVSYRR-NAFAQMKLPKYALP-----KDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSS-----------RGPEGNIMIDLYEVAGIKGMFLANKKI----DNQVKTFITYNKGRDWRLLQAPDTDLRGDP-VHCLLPY-CSLHLHLKVSENP---YTSGIIASKDTAPSIIVASGNIG--SELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT----SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRR-CAEEDYRPWQLHS-----QGEACIMGAKRIYKKRKSERKCMQG-KYAGAMESEP--CVCTEADFDCDYGYERHSN-----GQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG-VREQYTAKPQKCPGKA-------------------------------------------------------------------------------------------------------------------------PRGLRIVTADGKLTAEQGHNVTLMVQLEEGD--------------------------------------VQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDN----------------------SLGS-----------------------------DSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN--------------------------------------------------------------------------------------------------------------------------------TEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDDYNPD--IPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLP-YQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVD----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRR-------------------------VA-----------------LPSPPSPS-TQPGDSSLRLQRAR------------------------HATPPSTPKRGS---AGAQYAI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN08-1", "uniprot_id": "A0A8M9PN08_DANRE", "id": "A0A8M9PN08-1", "name": "", "aln": "-----MERGIRYCRVHVRAFCTLLLILFAWVPVAETVITCRSCHLLDKWSGRE-----LLVKMDSGVDS-GKVGDQDGD-GSLFNLAGAETGQPDCGASDSGEHAHSVRKRNTESLRSGKTPPDEKWKSMRSHDKVYNLKLAASRATAPGDPHHR--VRRGTQEPGSPPGARFQPLGFGNVTARAARRVPRSELRWNRDERRTAAS---RQEELKLTSSTFALTGDSAHNQAMVHWSGQNSSVILMLTKL-YDFNLGSVTES-SLWRSTDYGTTYEKLNEKVGV------KTILSYLYVSPNNKRKIMLLTD--PEVESSLLIS------SDEGATYQKYRLNFY-ILSLLFHPEQEDWILAYSH-----EQKLYSSVEFGRRWQLVHERVAPNRFYWSKTGLDKEPGLIHLETSISESQALYVTCKLQNCTDANKGKPFPGYIDPNS----LVVQDEYVFVQVSTGGRPIYYVSSRR-DVFTPMKLPKYTLP-----KDLHVISTDENRVVAAVQEWNQNDTYNLYVSESGGIYYTLALENVMSS-----------MGPEGNVMIDLYEVAGIKGMFLANKKL----NNEVKTYITYNKGRDWRLLQAPSADLRGNR-IHCMLPY-CSLHLHLHVSANP---YTSGNIASRESAPGIILASGSIG--AELTSSNVSMFITSDAGNTWRQIFDEEYSVLYLDQGGALVAIRHT----PLPIRHLWLSFDEGRVWNKYSFTSSPLFVDGVLGEPGEETLIMTIFG--HVSHRSEWQLVKIDFRSIFNRR-CVESDYVPWDLHD-----QGERCLMGVKRVYRKLKATARCVMGKTYSVTMISEP--CHCTESDFECDYGFERRTD-----GKCTPAFWFPPSSMSRTCTTEHTFLNSTGYRKVVSNNCTGG-VIERYTARRQLCPSQA-------------------------------------------------------------------------------------------------------------------------PRGLHLVTSEGKLTATLASNVTFLVFLEEGD--------------------------------------GSKTSITVDFGDGNAFTYSNVSSIEDGIKHIYKTVGIYRVSATAEN----------------------SLGS-----------------------------ETVLLFLHVTCQLDSIHLSAPFVAVKNKEVNLTVVLYPSQVGTVTYIWWFGNN--------------------------------------------------------------------------------------------------------------------------------SEPVITLDGSVSFTFSREGISIVTVQVSAGNNILQDRKTIAVHEYFRSHLLAFSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDDHNPD--VAEWRLDVSRVIKTSMMQATGVSPDLLLVTVLPGLPTAAEFFLLPDKQLTEGKPDKTATHLDQLSEVVLSALNQNLVQFTLRPGVQITVYAAHLSAAPLVD----------------------TSENHSGSAMLMLLSVVVLGLAIFLIYKFKRK-------------------------IPGLHVYAAMQDEKEQE-MIQSPVSPTDSTPSSSSQRELLTS------------------------LEPLDTEPNTQTIECIKPHPRVKFSSDLPTYIDV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VI51-1", "uniprot_id": "SORC3_MOUSE", "id": "Q8VI51-1", "name": "VPS10 domain-containing receptor SorCS3", "aln": "MEAAGTERPAGWPGAPLARTGLLLLSTWVLAGAEITWGATGGPGRLVSPASRPP---VLPPLLPRAAENRWPEELASARRAAAPRRRSRLEPLSQASRG---EIRTEAAGMSPEGARWVPGIPSPSQAGSARRTRRAQ----------PPSPLERGDSWATALADGAKGS---RPHTKG-----------------SREEVRATRTGGASTEELRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKL-YDFNLGSVTES-SLWRSVDYGATYEKLNDKVGL------KTVLSYLYVNPTNKRKIMLLSD--PEMESSVLIS------SDEGATYQKYRLTFY-IQSLLFHPKQEDWVLAYSL-----DQKLYSSMDFGRRWQLMHERITPNRFYWSVSGLDKEADLVHMEVRTADGYAHYLTCRIQECAETTRSGPFARSIDISS----LVVQDEYIFIQVTIGGRASYYVSYRR-EAFAQIKLPKYSLP-----KDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSS-----------RGLMGNIIIELYEVAGIKGIFLANKKV----DDQVKTYITYNKGRDWRLLQAPDVDLRGSP-VHCLLPF-CSLHLHLQLSENP---YSSGRISSKDTAPGLVVATGNIG--SELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHT----PLPVRHLWVSFDEGHSWDKYGFTLLPLFVDGALVEAGVETHIMTVFG--HFSLRSEWQLVKVDYKSIFSRR-CTKEDFETWHLLN-----QGEPCVMGERKIFKKRKPGAQCALGREYSGSVVSEP--CVCADWDFECDYGYERHGE-----SQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDG-LRDKYSAKTQLCPGKA-------------------------------------------------------------------------------------------------------------------------PRGLHVVTTDGRLVAEQGHNATFIILMEEGD--------------------------------------LQRTNIQLDFGDGVAVSYANFSPIEDGIRHVYKSAGIFQVTAYAEN----------------------NLGS-----------------------------DTAFLFLHVVCPVEHVHLRVPFVAIRNKDVNISAVVWPSQLGTLTYFWWFGNS--------------------------------------------------------------------------------------------------------------------------------TKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDYHNPD--IPEWRQDIGNVIKRALIKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERR-KGHEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVD----------------------SSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRK-------------------------IPWINIYAQVQHDKEQ--EMIGSVSQSENAPKITLSDFTEPE-------------------------ELLDKELDTRVIGSIATIASSESTKEIPNCTSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPU3-1", "uniprot_id": "SORC3_HUMAN", "id": "Q9UPU3-1", "name": "VPS10 domain-containing receptor SorCS3", "aln": "MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPP---ALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQ----------PPITQERGDAWATAPADGSRGS---RPLAKG-----------------SREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKL-YDFNLGSVTES-SLWRSTDYGTTYEKLNDKVGL------KTVLSYLYVNPTNKRKIMLLSD--PEMESSILIS------SDEGATYQKYRLTFY-IQSLLFHPKQEDWVLAYSL-----DQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISS----LVVQDEYIFIQVTTSGRASYYVSYRR-EAFAQIKLPKYSLP-----KDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSS-----------RGLMGNIIIELYEVAGIKGIFLANKKV----DDQVKTYITYNKGRDWRLLQAPDVDLRGSP-VHCLLPF-CSLHLHLQLSENP---YSSGRISSKETAPGLVVATGNIG--PELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHT----PLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFG--HFSLRSEWQLVKVDYKSIFSRH-CTKEDYQTWHLLN-----QGEPCVMGERKIFKKRKPGAQCALGRDHSGSVVSEP--CVCANWDFECDYGYERHGE-----SQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDG-LREKYTAKAQMCPGKA-------------------------------------------------------------------------------------------------------------------------PRGLHVVTTDGRLVAEQGHNATFIILMEEGD--------------------------------------LQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAEN----------------------NLGS-----------------------------DTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNS--------------------------------------------------------------------------------------------------------------------------------TKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDYHNPD--IPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERR-KGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVD----------------------SSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRK-------------------------IPWINIYAQVQHDKEQ--EMIGSVSQSENAPKITLSDFTEPE-------------------------ELLDKELDTRVIGGIATIANSESTKEIPNCTSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Q0-1", "uniprot_id": "A0A8M9Q0Q0_DANRE", "id": "A0A8M9Q0Q0-1", "name": "", "aln": "-----METALGVFPGAHFTISTWLILFFPNVKADISCAPCMSPMQVNYAGDEHLRDPPDSGKYPTPPDQKKPKLIAVLYPNIGVPTDGFPGIAPKVETNADGINSRAPLGNFAESALDEELFSDEFMESGRVKRSVPEFMESAR----GADPLSEEQRKTSALRVDGQG----KRAEVR----------------WNREDEQDARVSDSRPEEPKLTSSTFALAGDSAHNHAVVYWSGKNSSVILILTKL-YDFHLGSVTES-TLWRSTDYGSTYERLNDKVGV------KTVLSYLYVCPTNKRKIMVLTD--PEFESSILIS------SDEGASYQKYRLNFF-VLSLLFHHTQEDWALAYSH-----DQKLYSSFDFGRKWQLVHERVTPNRFYWSVTGLDKEFDLVHMEAHTPDGHCQYVTCRAQACSESSRTHPFPGYIETNS----LVVQDEYVFVQVTTTGRASYYVSYQR-EAFIRIKLPKYSLP-----KDMHIVSTDQGQVFTAVQEWNQNDTYNLYISDTRGIYFTLALENVRTS-----------RGLGGNSMIDLYEVAGIEGMLIANRKV----ENQVKTYITYNKGRDWRLLQAPSTDLAGNP-IHCVLPF-CSLHLQLQMSENP---YLSGSISTKSSAPGVIVATGNIG--SELSYNNVAMFISSDAGNNWRQIFEEEHNVWFLDKGGALVAVKQP----TVPTRHLWISFDEGRQWTRHSFSAMPLFVDGVLVEAGAENQIMTFFG--HFSHRSEWQLIKIDYKSVFTRR-CTEGDYQTWHLHN-----QGEPCIMGQKQIYMKRRPGNYCMVGWDNSRILSAEP--CICRAHDFECDYGFERRGD-----GNCLPAFWFNPSIVSRSCSQGQNFLNSTGYRKVVANNCTKG-VKEMYTARKQQCPNRP-------------------------------------------------------------------------------------------------------------------------PRGLVLTTRDEKLTANMGSNVTFLVRLEEGD--------------------------------------SMRTNIQLDFGDGTAVSYSNLSWTQEGIKHVYRSAGIFRVTALAEN----------------------SLGF-----------------------------DTSSLYLHVTCPVEHIQLLAPYVVIKNKEVNLTAVVWPSHFRTLTYFWWLGNS--------------------------------------------------------------------------------------------------------------------------------TEPIVTLDSSISHTFSSEGMSTVTVQVSSGDSILQDSRTIAIQEFFKSLLLSFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLDEANPD--IPEWRLDVARVIKKAVLQVADVPEEQLLVAVFPGIPTAAELFLLPPRNQSNGR-KQTEEDLEQISEILVNALNQISVEFELKPGSRVIVYITQLTLAPLVD----------------------SIPRHSSSAMLMLLSVVFLGLAVFLIYKFKRK-------------------------IPWINIYAEVNHEKEQ--EMINTVGQNDATPKITLSEFSTQK-------------------------ELMEKELEARAKR--GVIHTCESTREIPNCTSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T6R5-1", "uniprot_id": "A0A8N7T6R5_DANRE", "id": "A0A8N7T6R5-1", "name": "", "aln": "----MINKKDALWFESSRTYWTLFCLCVLVPLPARAEITCASCFAPIRRNEEA-----LVEAKVKPSSDFGSVPDDSTDKNWIQALDG-AQLTSKAHRKSSSVSWREKLENAPKSSAEQTG-----EKGGKVYPTWSS----------EEIKVNRREKRSMFPPDHSPG----SRFEFR------------------RTGGVDGIGKSPRQNEPHLITSTFALSGDSAHNQAMVLWSGHNSSVILILTKL-FDFNLGTVTES-SLWRSVDFGTTYEKLTDKVMI------RTMLSYLYVCPTNKRKILILSD--PEVESSLLIS------SDEGASFQKFNINFY-IMSLLFHPTQENWILAYSH-----DQRLYSSVDFGKKWILVHERVTPGRFYWALSGLDKEADLVHIEARTDSGQMQYITCRAQKCSEEGRQYPFIGRIDTNS----LVVQDQYIFLQLTTAGRTTYFVSYQR-GPFRTIQLPKYCLP-----KDMHIVSTDEGQVLAAVQEWNENDTYSLYISDTPGVYFTRSLPNLRTS-----------RGLAGNLIVDVYKVSGISGMIIANKKE----DAQMRTYITYNKGQTWSLLQPPAKDTTGHD-VNCNLPS-CSLHLHLQMSENP---YTPDTISTKQSAPGIIVATGNIG--PELSFSNTAMFISSDAGNTWRQIFEEEHSVWFLDHGGALLAVTQS----AVPTRYLWISLDEGRHWDKLSFSSTPLFVDGVLMTPETENRIITFFG--HFSYHSDWQLIKIDYSSLFGRK-CTDGDFQTWHLHN-----KGEVCVMGERQVYMKRKPGTRCTLGREYSRVVSAEP--CICTLYDFECDYGFERQTS-----GKCAPAFWYDVNLPAHTCSYGQRYRNSTGYRRVMLNNCREG-LKDTLSPRMQQCKPIA-------------------------------------------------------------------------------------------------------------------------PSGLQLSTINTQLTAVLGTNITFRVALQNGD--------------------------------------SLSTSLHVDFGDGISVSYSNISRLGDSITHTYRVAGIFRVSARAQN----------------------SQGS-----------------------------DSSSLYLHITSPVERIFLSAPVVVARGREANLTAVLWPSQPRTATFYWWFNNN--------------------------------------------------------------------------------------------------------------------------------TEPLITLEGSVSHTFTREGLNPVTVQVSAGGTVLQDVKIITVKDVFRSLLLSFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLEEHNPS--VAEWRQDVGRVVRATLAQVCSFPEDQLLVSVFPGSPTAAELFILPETNQSAFR-SHTEEQLNKMSEVFMNALNQNLIQFDLKPDTRVTVSLSQLTLAPLVD----------------------SSVLPSGSAMLLLVSLGLLGLAILFIYKFKRK-------------------------IPWIHVETEDSHEKEP--EMISAVGQEKNGTRTTATSFTSCSAHNTHTPCPLNTGTHNSFSHLPPPRELMEKELEAHSTGGLGAGERLR-TRQIPNCTNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88307-1", "uniprot_id": "SORL_MOUSE", "id": "O88307-1", "name": "Sortilin-related receptor", "aln": "------------MATRSSRRESRLPFLFALVALLPRGALGGGWTQRLHGGPAP------------LPQDRGFFVVQGDPRDLRLGTHG---------------DAPGASPAARKPLRTRRS----------------------------------------------------------------------------------------AALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALAR--DSLALARPKSS-DVYVSYDYGKSFSKISEKLNFGVGNNSEAVISQFYHSPADNKRYIFVDA----YAQYLWIT------FDFCSTIHGFSIPFR-AADLLLHSKASNLLLGFDRSH--PNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDQ-PNAIYIERHEPFGFSTVLRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGR-KPMRAAQFVTKHPIN-----EYYIADAAEDQVFVCVSHSN--NSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEK-INCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVG--KNLAS-KTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQG-----METNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGS-NKESVHSWLILQVNATDALGVP-CTENDYKLWSPSDE----RGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVG-ESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEG--------------LPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DSP1-1", "uniprot_id": "SORL_RAT", "id": "P0DSP1-1", "name": "Sortilin-related receptor", "aln": "------------MATRSSRRESRLPFLFTLVALLPPGALGGGWTQRLHGGGAP------------LPQDRGFFVVQGDPHELRLGTHG---------------DAWGASPAARKPLRTRRS----------------------------------------------------------------------------------------AALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALAR--DSLALTRPKSS-DVYVSYDYGKSFNKISEKLNFGVGNSSEAVISQFYHSPADNKRYIFVDA----YARYLWIT------FDFGSTIHGFSIPFR-AADLLLHSKASNLLLGFDSSH--PNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDQ-PNTIYIERHEPFGFSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYLFATKVVHLPGSQQQSSVQLWVSFGR-KPMRAAQFVTKHPIN-----EYYIADASEDQVFVCVSHSN--NSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMSEENMRSVITFDKGGTWEFLQAPAFTGYGEK-INCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVG--KNLAS-KTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQG-----METNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGS-NKESVHSWLILQVNATDALGVP-CTENDYKLWSPSDE----RGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDISLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYEHNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYRLVSEDVKWPNGISVDGHWIYWTDAYLDCIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSRSQVETLASQLTGLMDMKIFYKGKNAGSNACIPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGYLMCDCPQGYERKNNTCVKEENTCLRNQYHCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPISCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDATFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGRCIPNRWKCDRENDCGDWSDEKDCGDSHIFPSPTPGPSTCLPNYFRCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQLGQCDRFEFECRQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCMSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWIADFSGDVTLTWTRPKKMPSASCVYNVYYRVVG-ESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLSKVHNTNDFVTLRTPEG--------------LPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTTKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLNFRGGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPLAFEHILTRGISPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVQIGKTSAVIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMFDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGGDATVVQTARSTDVAAVVVPILFLILLSLGVGFAVLYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92673-1", "uniprot_id": "SORL_HUMAN", "id": "Q92673-1", "name": "Sortilin-related receptor", "aln": "------------MATRSSRRESRLPFLFTLVALLPPGALCEVWTQRLHGGSAP------------LPQDRGFLVVQGDPRELRLWARG---------------DARGASRADEKPLRRKRS----------------------------------------------------------------------------------------AALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVALAR--DSLALARPKSS-DVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFADA----YAQYLWIT------FDFCNTLQGFSIPFR-AADLLLHSKASNLLLGFDRSH--PNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDK-PNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGR-KPMRAAQFVTRHPIN-----EYYIADASEDQVFVCVSHSN--NRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEK-INCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVG--KNLAS-KTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQG-----METNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGS-NKENVHSWLILQVNATDALGVP-CTENDYKLWSPSDE----RGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNACVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVG-ESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEG--------------LPDAPRNLQLSLPREAEGVIVGHWAPPIHTHGLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG-SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVECTWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQARCLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHU5-1", "uniprot_id": "SORT_MOUSE", "id": "Q6PHU5-1", "name": "Sortilin", "aln": "-------MERPRGAADGLLRWP--LGLLLLLQLLPPAAVGQDRLDAPPPPAPP--------LLRWAGPVGVSWGLRAAAPGGPVPRAG--------------RWRRGAPAEDQDCGRLPD-------------------------------------------------------------------------------------------FIAKLTNNTHQHVFDDLSGSVSLSWVGDSTGVILVLTTFQVPLVIVSFGQS-KLYRSEDYGKNFKDITNLINN---TFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRS------SDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALST-----ENGLWVSKNFGEKWEEIHKAVCL--AKWGPNNIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFG--------LGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQE-----QFYSILAANEDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYT--------------TTGGETDFTNVTSLRGVYITSTLS---EDNSIQSMITFDQGGRWEHLRKPENSKCDAT-AKNKNECSLHIHASYSISQKLN---VPMAPLSEPNAVGIVIAHGSVG--DAISVMVPDVYISDDGGYSWAKMLEGPHYYTILDSGGIIVAIEHS----NRPINVIKFSTDEGQCWQSYVFTQEPIYFTGLASEPGARSMNISIWGFTESFITRQWVSYTVDFKDILERN-CEEDDYTTWLAHSTDPGDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQPSV--CPCSLEDFLCDFGYFRPEN----ASECVEQPELKGHELEFCLYGKEEHLTTNGYRKIPGDKCQGG---------------------------------------------------------------------------------------------------------------------------------------------MNPAREVKDLKKKCTSNFLNPTKQNSKS------------------------------------------------------NSVPIILAIVGLMLVTVVAGVLIVKKYVCG--------------------------------------------------------------------GRFLVHRYSVLQQHAEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGVEALDSTSHA-KSGYHDDSDEDLLE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54861-1", "uniprot_id": "SORT_RAT", "id": "O54861-1", "name": "Sortilin", "aln": "-------MERPRGAADGLLRWP--LGLLLLLQLLPPAAVGQDRLDAPPPPAPP--------LLRWAGPVGVSWGLRAAAPGGPVPRAG--------------RWRRGAPAEDQDCGRLPD-------------------------------------------------------------------------------------------FIAKLTNNTHQHVFDDLSGSVSLSWVGDSTGVILVLTTFQVPLVIVSFGQS-KLYRSEDYGKNFKDITNLINN---TFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRS------SDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALST-----ENGLWVSKNFGEKWEEIHKAVCL--AKWGPNNIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFG--------LGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQE-----QFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYT--------------TTGGETDFTNVTSLRGVYITSTLS---EDNSIQSMITFDQGGRWEHLQKPENSKCDAT-AKNKNECSLHIHASYSISQKLN---VPMAPLSEPNAVGIVIAHGSVG--DAISVMVPDVYISDDGGYSWAKMLEGPHYYTILDSGGIIVAIEHS----NRPINVIKFSTDEGQCWQSYVFSQEPVYFTGLASEPGARSMNISIWGFTESFLTRQWVSYTIDFKDILERN-CEENDYTTWLAHSTDPGDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQPSI--CPCSLEDFLCDFGYFRPEN----ASECVEQPELKGHELEFCLYGKEEHLTTNGYRKIPGDRCQGG---------------------------------------------------------------------------------------------------------------------------------------------MNPAREVKDLKKKCTSNFLNPKKQNSKS------------------------------------------------------SSVPIILAIVGLMLVTVVAGVLIVKKYVCG--------------------------------------------------------------------GRFLVHRYSVLQQHAEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGVEALDTASHA-KSGYHDDSDEDLLE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99523-1", "uniprot_id": "SORT_HUMAN", "id": "Q99523-1", "name": "Sortilin", "aln": "-------MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAP--------LPRWSGPIGVSWGLRAAAAGGAFPRGG--------------RWRRSAPGEDEECGRVRD-------------------------------------------------------------------------------------------FVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQS-KLYRSEDYGKNFKDITDLINN---TFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRS------SDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALST-----ENGLWVSKNFGGKWEEIHKAVCL--AKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIYSFG--------LGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQE-----QFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYT--------------TTGGETDFTNVTSLRGVYITSVLS---EDNSIQTMITFDQGGRWTHLRKPENSECDAT-AKNKNECSLHIHASYSISQKLN---VPMAPLSEPNAVGIVIAHGSVG--DAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS----SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERN-CEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSI--CLCSLEDFLCDFGYYRPEN----DSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGG---------------------------------------------------------------------------------------------------------------------------------------------VNPVREVKDLKKKCTSNFLSPEKQNSKS------------------------------------------------------NSVPIILAIVGLMLVTVVAGVLIVKKYVCG--------------------------------------------------------------------GRFLVHRYSVLQQHAEANG---------------------------------------------------------------------------------------------------------------------------------------------------------------------VDGVDALDTASHTNKSGYHDDSDEDLLE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUT7-1", "uniprot_id": "SORT1_DANRE", "id": "Q6NUT7-1", "name": "Sortilin", "aln": "-------MS---------------TVLCCVLVLLISVALCMDFEERPSSSWRS--------EQTMFLKSHKSRNLLSLR-DLQQPDHG--------------KMKRSEESAQNQCESLHG-------------------------------------------------------------------------------------------YQSTLQNDTHTHNFNDLSGSVSLAWVGDGTGVLLVLTTFQVPLFIMRFGQS-KLYRSEDYGKTFQDITDLINN---TFIQTEFGIAIGPDNSGKVILTGDLAEG-KVTKIFRS------VDFGKSFVTSELPFHPLMQITYNPKDSNILMVYSI-----NYDLWLSKDFGANWKKIHESVCL--VKWGIDDTIFLTTNPNGSCS-DRGTLELRKSLDYGKTFKTIGNRIYSFG--------LGGRFVFASIMTDSGSTRMIHVSVDQGETWDMAQLPTVGHE-----QFYSILAANNDMVFMHVDEPGDSGIGTIYISDDRGIVFSKSLERHLYT--------------TTGGDTDFTNITSLRGVYITSVLA---EDGSVQTVITFNQGGEWRPLMKPWNGVCDST-AKHPSECSLHIHASYSISMKLN---VPMQPLSETNAVGLVLAHGSVG--GAVSVLSPDVYVSDDGGYTWFQALKGPHHYAILDSGGLLVAVEHNP---THPISQIKFSTDEGQCWHAHNFTDDPIYFTGLASEPGARSMNVSLWGYRDTILNQYWVSVTVDFRQLLSRD-CQENDYIQWLAHSSDINSPTDGCVLGYKERFLRLRRDSVCWNGRDYKVTKEPTT--CPCTLTDFH-DFGFYHEEN----SSVCVEQPDLIGHSLEFCLHGRKEQLQTSGYRKIPGDHCEEG---------------------------------------------------------------------------------------------------------------------------------------------ITPERKEIDLSKKCVSNLLRTEQLTKEHS----------------------------------------------------FNSAPIIAVVIIVLLISAVAGVIFIKKYVCG--------------------------------------------------------------------GRFLVHRYSVLQQHAEANG---------------------------------------------------------------------------------------------------------------------------------------------------------------------IDGLDDLDTLEGG-KTHYHDDSDEDLLE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "-------------------MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSR--------------------------------------------------YVFDIVNFDDSN------------------------------------------------------------------------------------------------TLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPISEK----ASNYFCDVTTHPIKKKHLIIRCDLLTIKNSGLMYVGREIYTTNDGVSFSQVKPSFGKIDGHISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTGSTIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISN-------DVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRER-----DDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGT--------------FFGSFHPFIEYSDRKRKYSRQKVR-------EETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLN------------PSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDL-IMPIYPYRLVSTISDGSGSKFILTGTSITEDPIFITYSIDFSAVFDYKSCEEGDFEDWNLADG-------KCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAK-----GDCIPDYNLIALSDICDKSKGKSVLVKP-LQLIKGDKCKTPMKIESVDIPCDEIPKEG-------------------------------------------------------------------------------------------------------------------------SSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIG---------------DAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEAR---------------------QLGMP---------------------LDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYP------------------------------------------------------------------------------------------------------------------------------SNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSD------WNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGR-----------------------KRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPDGFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLGASNIPDALPARSASHESDLAAARSEDK--------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :: . : .: : * * .: :. . . : : : . * . : : . : . . :. : : . *. .. . .: * . . . : :: ::* * * . :: : .::: * :* ::: . * * * *. : : : * ::* * : .:: . . : :: : * . *: * . *: * . : : * * *: .: : . . : : : * . : : ", "identical_positions": 26, "similar_positions": 95, "identity": "1.08%" }, { "cls_id": "homologset.agr.SGD:S000001440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNE4-1", "uniprot_id": "EPAB2_RAT", "id": "B0BNE4-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MWPSLSNELFPPP--------------TEVWLQTVSSDPEAQGWGAWGRTEKTSLVPSAGS----DKEAEENE-----DSSFLLSLLEPENLAKSPVYNQELEAIRLKLWTMEHAEVLPEPPSVQRKATEEERAEARELLSPETIGCFFPGAPKENVEADHRSVYVGNVDYGGSAAELEAYFSPCGEIHRVTILCDKFSGHPKGYAYIEFASKSSVQAAVRLDESTFRGRVIKVLPKRTNFPGIS----STDRGGLRTHSSSR-AAFL-QGSLQRKPRLRPHGQS---RGRGRASPWFSPY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XFR0-1", "uniprot_id": "EPAB2_MOUSE", "id": "Q5XFR0-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MEPYLSNELFPPP--------------TEAWLQTVSSDPEAQGWGAWGRTEKTSLVPRAGSRAGSDKEAEENE-----DASFLLSLLEPENLAKSPVFNQELEAIKLKLWAMEHAEAQPEPPCVQRKATEEERAEVRQLLSPETVDCFFSRTSKENVEADHRSVFVGNVDYGGSAAELEAYFSPCGEIHRVTILCDKFSGHPKGYAYIEFASHRSVKAAVGLDESTFRGRVIKVLPKRTNFPGIS----STDRGGLRTHSGNR-AAFL-HGSLHRKARLRAHGRS---RGHGGAPQWFSPY-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDY0-1", "uniprot_id": "EPAB2_HUMAN", "id": "A6NDY0-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MWPFPSRSLFPPP--------------TQAWLQTVSSDPEAQGWGAWN-ETKEILGPEGGEGKEEKEEEEDAEEDQDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTAAGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILCDKFSGHPKGYAYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGIS----STDRGGLRGHPGSRGAPFP-HSGLQGRPRLRPQGQN---RARGKFSPWFSPY-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CCS6-1", "uniprot_id": "PABP2_MOUSE", "id": "Q8CCS6-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEADPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRSRYRARTTNYN-SSRSRFYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7Z8-1", "uniprot_id": "G3V7Z8_RAT", "id": "G3V7Z8-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVETDPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYN-SSRSRFYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86U42-1", "uniprot_id": "PABP2_HUMAN", "id": "Q86U42-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYN-SSRSRFYSGFNSRPRGRVYRGRARATSWYSPY-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KNF2-1", "uniprot_id": "PABP2_DROME", "id": "Q7KNF2-1", "name": "Polyadenylate-binding protein 2", "aln": "-----------------------------------------------MADEDITLNEDQLL-------ESLEETN------------------GEQETEIATEVEE----EGSMQIDPELEAIKARVKEMEEEAE-------KIKQMQSEVDKQMAGGSTTG-LATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLS----TTNR-FARGSFRGRGAR---VSRACCHSTFRGARRAMGYRGRA---NYYAPY-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QC75-1", "uniprot_id": "A0A8M9QC75_DANRE", "id": "A0A8M9QC75-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------MDES------------DMQYEVERQFPYS--PEAELFFDMTHEERIDSDRRSIYVGNVDYGATADELEMYFNSCGHVNRVTIPYNRFTGHPKGFAYIEFSDRESVRTAMALDETLFRGRVIKVSPKRTNIPGFS----TTDVYLRGGWSRGRGVR------ASRFNPFRGCRFIRSVLPTYNTTSCHVEN-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40561-1", "uniprot_id": "SGN1_YEAST", "id": "P40561-1", "name": "RNA-binding protein SGN1", "aln": "--------------------------------------------------------------------------------------------------------------MSQEEKVDAKATLKTEISNNKKNDKQ------ELELDELVGKLSIEGTPQVSQKLSKEEKHAHQLEADSRSIFVGNITPDVTPEQIEDHFKDCGQIKRITLLYDRNTGTPKGYGYIEFESPAYREKALQLNGGELKGKKIAVSRKRTNIPGFNRHYNSQNQYFQQWQWNYPLMAYPNPDTFPYYPPYPPNQSPNQNFGYNKNNYYRSPYNNKNRTFQKKHFNSAKDSTKNIRSTSQKPVVMPSDNVKSSTQEKDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .. : * **::***: . :. ::* :* ** ::*:*: :: * ***:.**** . :: :: ::*: * * **** **:. : : ", "identical_positions": 29, "similar_positions": 35, "identity": "7.92%" }, { "cls_id": "homologset.agr.SGD:S000001441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7F0-1", "uniprot_id": "A0A0G2K7F0_RAT", "id": "A0A0G2K7F0-1", "name": "RNA helicase", "aln": "MSGRQRTLFQTWGPSLVRGAGAPGCGQ----PRSP--------AVTESLPEEDDEVLLVAAYEAEQQLDPGDGGFCAAAGALWIYPTNCPVRDYQLDISRTALFCNTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQMEACFHVMGIPQSHMAEMTGSTQAVNRKEIWSSRRVLFLTPQVMVNDLTRGA----VPAAHVKCLVVDEAHKALGNYAYCQVVRELVKYTNHFRILALSATPGSDIKAVQQVITNLLIEKIELRSEDSPDILPYSHERRVEKLVVPLGEELGAIQKTYVQILETFASSLIKRNILMKRDIPNLTKYQIILARDQFRKNPSPNIVGVQQGIIEGELAICISLYHGYELLQQLGMRSLYFFLSGIMDGTKGMTRVKTELSRNEDFTKLYSHLQSVFAHVRDAAAASEASAFQKGNKEKKFVYSHPKLKKLEEVILEHFKSWNAKNTTEKKCQESRVMIFSSFRDSVEEIAEMLSQHQPGVRVMTFVGHASGKNTKGYTQKEQLRVVRQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDAQKS-PIRLIQRMGRTGRRRQGRIVVILAEGREERTYNQSQSNKKNIYKAIS-GNRQVLRLYQGSPRMVPDKINPELHKMFITHGVYESEK-ARSVQRKS--FSSRSGIKAGNSNKDGLLSEEEFNLWNRLYRLGDSDTVKGVALPRSHFLSLQ--EDRVAQEPTTGIHQLSLSEWSLWQDHPLPTHQVEHSDRCHHFISIMRMIEGMRHEEDECSYELKIKP----------------FLQMEDVYSKYNAPRNGYKNVASVTRIAPKKSSFRPSVDAGGSLSVTESEEGCADTVEQMDSEWTKITSLREKATTVG-KGQTREQTDDDHDDADS--SDSDRNSPADVVSRV-PPSGERVADVGGIPILGAVTE-DDSHTGTLLMECQVTEKSLARYS---LDSGYSSFSDDKSLSSHLFLPLEEELYTERAAELFYRCQPMTEEVLANVEKFLSHSPPSLSGLSDVEYAVTQGFELDNESCLPYPEREHSPKPGSPYPEREHSPKPASLALYTAVNSQSNLELNSAKHTNPPSEKDCLPATTHNNIPDQPSFCDSDSETHNIKNQNLVSNSYGQIQVNLENNLVDENSHDD--SEPPVLFTDEDESLLLFEDDLKNIEDGTEELNGVGLPPLDRISQPLCVSDKTLISEMPPVSHFLISDELLDDD-SEPEDQIICDTK---CWEGVEGRDEEIKTEGQPFDCSADLFSVTFDLGF-CSSGSDDENPARASDRSSTLGTAEVPGRHSD-KEVKDASHAS--GPLGGTISP--------IPSEK---------MPWSPCAQSKECAPFHSALSLPVRERAMSTPLSKAHRS---SKTGAHVLKTLDSTKEKAGGQGFKVTLNPRFDNLGFSVEETKSSDQLSVYQSPRCPKVEHLTS--ESEDD-VFLKKTRKPKGNVLKSPEDQKNNEVDSPIHVVKKSR--VLRSELSSSDDESENFHRPCPKLEYFKDRNRNTRKGSKAQKKRIHMKALARGFLDEEAEVSGEDADCVSSDEGDDSENEKDSSLLDFVNDRTQLSQAINDSEMRAIYMKSVRSPLMSTKYKMVREKHNSMNIFSQIPEQDENYLEDSFCVAEEESCRSQSSEEEIFVDFNLTKDSFTDEDIRYKTRHAVKLKQMNKKQNCTRSRKKLSRIILPDSDSSEEENTANGREDPSAGG-HAADKHTQQGQLWASGPSGS-VQPKVLCNPAGNQSSGQRLQVLPNIMDAVPGALNVRAQSHNQTKSTSPPCASVESRKECGNRPVQLKVGDQ----DTSAAPCSASLLPDAEVLIAPRHPREGNRACILVDSREITTGLEVISSLRTVHGLQVEICPLNGCDYIVSNRMVVERKSQSEMLSNTAKNKFIEQIQRLQSMFQRICVIVEKDRE-KAGDISKMFRRTKCYDSLLTALVGAGIRILFSSGQEETAGLIKEL---SLVEQRKNAGIHIPAVLDTGTCEALQFYLSIPGVSYVTALNMCHQFSSVKKMVNSSPEEISTCAQVTHQKAEEIYKYIHYTFDMQMLPNDLTQERQKSETCSTL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGE5-1", "uniprot_id": "FANCM_MOUSE", "id": "Q8BGE5-1", "name": "Fanconi anemia group M protein homolog", "aln": "MSGRQRTLFQTWGPSLVRGSGDSGCGQ----PRSP--------AMAEALPEEDDEVLLVAAYEAERQLDPGDGGFCAAAGALWIYPTNCPVRDYQLDISRSALFCNTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQMEACFHVMGIPQSHMAEMTGSTQAVNRKEIWSSRRVLFLTPQVMVNDLTRGA----VPATHVKCLVVDEAHKALGNYAYCQVVRELVKYTTHFRILALSATPGSDIKAVQQVITNLLIGKIELRSEESPDILPYSHERRVEKLVVPLGEELGAIQKTYIQILETFASSLIHRNVLMKRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGEFALCISLYHGYELLQQMGMRSLYFFLSGIMDGTKGMTRARNELSRNEDFMKLYTHLQSAFAP----ASTSDASAFQRGNKEKKFVYSHPKLKKLEEVILEHFKSWNAKATTEKKCHESRVMIFSSFRDSVEEIAEMLLQHRPVIRVMTFVGHASGKNTKGFTQKEQLQVVRQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDAQKS-PIRLIQRMGRTGRKRQGRIVVILAEGREERTYNQSQSNKKNIYKAIS-GNRQVLRLYQGSPRMVPDKINPELHKMYITHGVYEPEK-ARSVQRRP--FSSRGGIKASKSNKDGLLSEEEFNLWSRLYRLGDSDQVKGVALPQSHFPSLQ--EDRVIQDPTTRIHQLSLSEWSLWQDRPLPTHQVDHSDRCHHFISIMKMIEGMRHEEGECSYELKIRP----------------FLQMEDVCSKYHAPRNGYNNVASVASSAHQKSSFRPSVDAGGSLTVIESEEEHADTVKQRDSKWTKITSLREKPCRAGRKGQTCEHSEGEGEDGDAGSSDADGQSPAEADSQVDPPSGERMADVGGISILGAVTE-EDNHPGTLQMECQVTNKSCARYS---LDSGYSSFSDEKSVSSNLFLPLEEELFTDRAAEQFYNCRPMTEDVLANVERFLSRSPPSLSGLSDLVYDVTQGCEFDNASCSPYPEHEHSPRPVSP-------------ASHSAGNSQQNLESNSAKRISHPTEKYCLPGTTHNKVSDRPSFCESDSEGHNIKYQNSGSNSCAQIQADLENNFVDKNSHDD--SEPPVLFTDEDESLLLFEDDFKNIEDGPEELNGASLPPFNSISQPLRVSGKTLTSEMPPVSHFLISDELLLDDDSEPEDQIVCGAKSWKCQEGVEDGQEELRTDGQTFDCSVDLFSVTFDLGFRCSSGSDDEMLAGASDRTRTLGAADVSGRHSD-KEIKDAGGAS--GPLGRAISP--------IPTET---------AQWSPWAQNKEYASFHVASSSPVKQRVRSTPLSKSHAS---SKTGAHMLKTLDSTKEKAGGQGFKMALNPRLGHLGFSVEETKSSDQVFVHQSPRRTEVEHLTS--ESEDD-VFLRKTKKPKRNVLKSPEDQKNNEVDSPIHAVKKPR--VLRSELASSDDESENFGRTCPRLEHFKGRNRNIRKGSAAQKNRSQVKTMARRFLDDEAEVSGEDVDCVSADEEDESENEQDSSLLDFVNDRTQLSQAINDSEMRAIYMKSVRSPLMSTKYRMVREKRPNMNIFSQIPEQDENYLEDSFCVDEEESCKSQSSEEEISVDFNLTKDSFTDEDIRYKTRYAVKIKQMNKKQNYTRPRKKLSRIILPDDDSSEEENIPKDREHSVAGG-HAAAEHTQQGQLWASGPSGSSVPPQVLSDPSWNQSSRQRLQVQPSITDAVPRTLNVKAQSHNKIKSASPPCTGVESRKEYGNHPVQLKADSQEH-SDTSAAPCSTSLLHVAEGHTAPRHLQEGNRACILVDSREITTGLEVISSLRTVHGLQVEICPLNGCDYIVSSRMVVVRRSQSEMLSNTSKNKFIEQMQRLQSMFQRICVIVEKDRE-KAGDTSKKFRRTKCYDSLLTALVGAGIRILFSSGQEETADLLKEL---SLVEQRKNAGIHIPAVLNTSKLEALPFYLSIPGISYITALNMCHQFSSVKKMANSSPEEISTCAQVNHQKAEEIYKYIHYIFDMQMLPNDLNQERQKPDTCLTLGVAMKELS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYD8-1", "uniprot_id": "FANCM_HUMAN", "id": "Q8IYD8-1", "name": "Fanconi anemia group M protein", "aln": "MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVAAYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRGA----CPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAIQKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGEFAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMFARTR-STSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKS-PIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQSQSNKRSIYKAIS-SNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELEVES----------------YLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKEIKKDQLKKE--NNHGIIDS--VDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCL-------------LSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQ-NENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDVNT-------EFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGF-CSPDSDDEILEHTSDSNRPL--DDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSD-ESENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEM-MEQNCAHSKKKLSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDRE-KTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEETADLLKEL---SLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLNQDRLKSDI--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R5F7-1", "uniprot_id": "IFIH1_MOUSE", "id": "Q8R5F7-1", "name": "Interferon-induced helicase C domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------MSIVCSAEDSFRNLILFFRPRLKMYIQVEPVLDHLIFLSAETKEQILKKINTCGNTSAAELLLST------------------------------LEQGQWPLGWTQMF----VEALEHSGNPLAARYVKPTLTDLPSPSSETAHDECLHLLTLLQPTLVDKLLINDVLDTCFEKGLLTVEDRNRISAAGNSGNESGVRELLRRIVQKENWFSTFLDVLRQTGNDALFQELTGG----GCPEDNTDLANSSHRDGPAANEC----------------------LLPAVDESSLETEAWNVDDILPEASCTDSSVTTESDTSLAEGSVSCFDESLGHNSNMGRDSGTMGSDSDE-SVIQTKRVSPEPELQLRPYQMEVAQPALDGK-----------------------------------------------------NIIICLPTGSGKTRVAVYITKDHLDKKKQA------------------------SESGKVIVLVN-----KVMLAEQLFRKEFNPYLK-KWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENS--------------------------------------------------------------------------------------------LLNLESGDDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRR----------------YLKQKLRNNDLKKQNKP-------AIPLPQILGLTASPGVGAAKKQSEAEKHILNICAN-------------------------------------------------------------------------------------------------------LDAFTIKTVKENLGQLKHQIKEPCKKFVIADDTRENPFKEKLLEIMASIQTYCQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSPMS-DFGTQHYEQWAIQMEKKAAKDGNRKDR---------------------------------------VCAEHLRKYNEALQINDTIR-------------------MIDAYSHLETFYTDEKEKKFAVLNDSDKSDD-EASSCNDQLKGDVKKSLKLDETDEFLMNLFFDNKKMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSRGIIFTKTR----QSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEV--------------------KPMTQTEQKEVISKFRT----------GEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVTSSGSGVTERE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQSILEKKMKVKRSIAKQYNDNPSLITLLCKNCSMLVCSGENIHVIEKMHHVNMTPEFKGL---YIVREN-KALQKKFADYQTN--------------GEIICK-CGQAWGTMMVHKGLDLPCLKIRNFVVNFKNNSPKKQYKKWVELPIRFPDLDYSEYCLYSDED-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6W5-1", "uniprot_id": "G3V6W5_RAT", "id": "G3V6W5-1", "name": "Interferon-induced helicase C domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------MSTVCSAEDSFRNLISIFRPRVKMNIQVEPVLDYLVFLPAETKEQILRKVTTCGNTSAAELLLST------------------------------LEQGQWPLGWTQMF----VEALEHSGNPLAARYVKPSLTDLPSPSSETAHDECLHLLNLLQPTLVGKLLINDVLDTCSEKGLVTVEDRNRISAAGNSGNESGVRELLRRIVQKENWFSTFLDVLRQTGNDALVQELTGV----SCPEESTDLDNASHKDRPAANEP----------------------LLPAIDALSLETEAWTIEDTSPEASFADSSVTTESDTSLAEGSVSCFDESLGHNSNMGRDSGTMGSDSDEDTIMGTKRASPKPELQLRPYQMEVAQPALDGK-----------------------------------------------------NIIICLPTGSGKTRVAVYITKDHLDKKKQA------------------------CESGKVIVLVN-----KVMLAEQLFRKEFNPFLK-KWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENS--------------------------------------------------------------------------------------------LLNLESGEDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRR----------------YLKQKLKNHKLKKQNKP-------TIHLPQILGLTASPGVGAAKKQSEAEKHILNICAN-------------------------------------------------------------------------------------------------------LDAFTIKTVKENLSQLKHQIKEPCKKFVIADDTRENPFKEKLLEIMASIQTYCQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSPLS-DFGTQHYEQWAIQMEKKAAKDGNRRDR---------------------------------------VCAEHLRKYNEALQINDTIR-------------------MIDAYSHLETFYTDEKEKKFAALNDSDESDDDEASSCHDQLKGNVKKSLKLDETDEFLMNLFFDNKKMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSRGIIFTKTR----QSTYALSQWIMENEKFAEVGVKAHHLIGAGHSSEV--------------------KPMTQTEQKEVISKFRT----------GEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVTSSGSGVTERE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQSILEKKMKVKRSIARQYNSDPSLITLLCKNCSTLVCSGENIHVIEKMHHVNMTPEFKGL---YIVREN-KALQMKFADYQTN--------------GEIICK-CGQAWGTMMVHKGLDLPCLKIRNFVVNFKNNSSKKQYKKWVELPIRFPDLDCSEYCLYSDED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYX4-1", "uniprot_id": "IFIH1_HUMAN", "id": "Q9BYX4-1", "name": "Interferon-induced helicase C domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKEQIQRTVATSGNMQAVELLLST------------------------------LEKGVWHLGWTREF----VEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNLLQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQKENWFSAFLNVLRQTGNNELVQELTGS----DCSESNAEIENLSQVDGPQVEEQ----------------------LLSTTVQPNLEKEVWGMENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAA--RASPEPELQLRPYQMEVAQPALEGK-----------------------------------------------------NIIICLPTGSGKTRVAVYIAKDHLDKKKKA------------------------SEPGKVIVLVN-----KVLLVEQLFRKEFQPFLK-KWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENS--------------------------------------------------------------------------------------------LLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRH----------------YLMQKLKNNRLKKENKP-------VIPLPQILGLTASPGVGGATKQAKAEEHILKLCAN-------------------------------------------------------------------------------------------------------LDAFTIKTVKENLDQLKNQIQEPCKKFAIADATREDPFKEKLLEIMTRIQTYCQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPMS-DFGTQPYEQWAIQMEKKAAKEGNRKER---------------------------------------VCAEHLRKYNEALQINDTIR-------------------MIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTR----QSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEF--------------------KPMTQNEQKEVISKFRT----------GKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKEL---YIVREN-KALQKKCADYQIN--------------GEIICK-CGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSDED-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99J87-1", "uniprot_id": "DHX58_MOUSE", "id": "Q99J87-1", "name": "ATP-dependent RNA helicase DHX58", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRPYQWEVILPALEGK-----------------------------------------------------NIIIWLPTGAGKTRAAAFVAKRHLET----------------------------VDRGKVVVLVN-----RVHLVSQHA-EEFRRMLD-KHWTVTTLSGDMGSRAGFGLMARSHDLLICTAELLQLA--------------------------------------------------------------------------------------------LNSSE--EDEHVELREFSLIVVDECHHTHKDTVYNTILSR----------------YLEQKLKK----------------AEPLPQVLGLTASPGTGGATKLQGAIDHILQLCAN-------------------------------------------------------------------------------------------------------LDTCHIMSPKNCYSQLLMHNPKPCKQYDLCQRRAQDPFGDLIKKLMNQIHQQLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDLKQQFGTQMYEQQVVQLCKDAAEAGLQEQR---------------------------------------VYALHLRRYNDALFIHDTVR-------------------ARDALDMLQDFYDRERTTKTQMVR-----------------------------AESWLLKLFDDHKNVLGQLAAR-GPENPKLEMLERILLKQFG-SPGHTRGIIFTRTR----QTASSLLLWLRQQPCLQTVGIKPQMLIGAGNTSQS--------------------THMTQKDQQEVIQEFRD----------GILSLLVATSVAEEGLDIAQCNVVVRYGLLTNEISMVQARGRARAGQSVYSFLATEGSREMKRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTNEALEVLMEKAVAAVQKMDPDEFKAKIRDLQQASLVKRAARAAHREIQQGQFLPEHVQLLCINCMVAVGYGSDLRKVEGTHHVNVNPNFSVY---YTTSQNPVVINKVFKDWRPG--------------GTIRCSNCGEVWGFQMIYKSVTLPVLKIGSILLETPRG--KIQAKKWSRVPFSIPVFDILQDCTQSLSELSLD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD46-1", "uniprot_id": "D3ZD46_RAT", "id": "D3ZD46-1", "name": "RNA helicase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRPYQWEVILPALEGK-----------------------------------------------------NIIIWLPTGAGKTRAAAFVAKRHLET----------------------------VDRGKVVVLVN-----RVHLVNQHA-EEFRRMLD-KQWTVTTLSGDMGSRAGFGLLARSHDLLICTAELLHLA--------------------------------------------------------------------------------------------LKSSE--EDEHVELTEFSLIVVDECHHTHKDTIYNTILSR----------------YLEHKLKK----------------AKPLPQVLGLTASPGTGGATKLQGAIDHILQLCAN-------------------------------------------------------------------------------------------------------LDTWRIMSPKNCYSQLLEHNPKPCKQYDLCQRRTQDPFGDLLKKLMKQIHQQLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDLKQQFGTQMYEQQVVQLSKDAAEAGLQEQR---------------------------------------VYALHLRRYNDALYIHDTVR-------------------AWDALNMLQDFYDTERALKTQMVH-----------------------------AERWLLELFDDHRKALAQFAAQ-GPENPKLEMLEGILLKQFG-SPDHTRGIIFTRTR----QTASSLLLWLRQQPCLQTVNIKPQMLIGAGNTGQS--------------------THMTQKDQQEVIQEFRD----------GKLNLLVATSVAEEGLDIAQCNVVVRYGLLTNEISMVQARGRARAGQSVYSFVATEGSREIKRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTNEALEVLMEQAVAAVQKMDPEEFKAKIQDLQLASLVKRAARAAHRESQQGQFPPDRVQLLCINCMVAVGYGSDLRKVEGTHHVNVNPDFSVY---YTTSQNPVVINKVFKDWKPG--------------GIIRCSNCGEVWGFQMIYKSVTLPVLKIRSMLLETPHG--KIQAKKWSRVPFSVPDFDILRDCTQSLSDLSLD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C10-1", "uniprot_id": "DHX58_HUMAN", "id": "Q96C10-1", "name": "ATP-dependent RNA helicase DHX58", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRSYQWEVIMPALEGK-----------------------------------------------------NIIIWLPTGAGKTRAAAYVAKRHLET----------------------------VDGAKVVVLVN-----RVHLVTQHG-EEFRRMLD-GRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMA--------------------------------------------------------------------------------------------LTSPE--EEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQ----------------YLELKLQR----------------AQPLPQVLGLTASPGTGGASKLDGAINHVLQLCAN-------------------------------------------------------------------------------------------------------LDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQIHDHLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELSRKFGTQMYEQQVVKLSEAAALAGLQEQR---------------------------------------VYALHLRRYNDALLIHDTVR-------------------AVDALAALQDFYHREHVTKTQILC-----------------------------AERRLLALFDDRKNELAHLATH-GPENPKLEMLEKILQRQFS-SSNSPRGIIFTRTR----QSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQS--------------------THMTQRDQQEVIQKFQD----------GTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQRENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNY---YNVSRDPVVINKVFKDWKPG--------------GVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQG--RIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6Q899-1", "uniprot_id": "RIGI_MOUSE", "id": "Q6Q899-1", "name": "Antiviral innate immune response receptor RIG-I", "aln": "---------------------------------------------------------------------------------------------------MTAEQRQNLQAFRDYIKKILDPTYILSYMSSWLEDEEVQYIQAEKNNKGPMEAASLFLQ------------------------------YLLKLQSEGWFQAF----LDALYHAG--YCGLCEAIESWDFQKIEKLEEHRLLLRRLEPEFKATVDPNDILSELSECLINQECEEIRQIRDTKGRMAGAEKMAECLIR--SDKENWPKVLQLALEKDNSKFSELWIVDK----GFKRAESKADEDDGAEASSIQIF----------------------IQEEPECQNLSQNPGPPSEASSNNLHSP--------------------------------------------------------LKPRNYQLELALPAKKGK-----------------------------------------------------NTIICAPTGCGKTFVSLLICEHHLKKFPC-------------------------GQKGKVVFFAN-----QIPVYEQQATVFSRYFER-LGYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNN--------------------------------------------------------------------------------------------LNNGA-----IPSLSVFTLMIFDECHNTSKNHPYNQIMFR----------------YLDHKLGES---------------RDPLPQVVGLTASVGVGDAKTAEEAMQHICKLCAA-------------------------------------------------------------------------------------------------------LDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTFKCIISQLMKETEKLAKDVSEELGKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FQIQNREFGTQKYEQWIVGVHKACSVFQMADKEEE-----------------------------SRVCKALFLYTSHLRKYNDALIISEDAQ-------------------MTDALNYLKAFFHDVREAAFDETE-------------------------------RELTRRFEEKLEELEKVSRDPSNENPKLRDLYLVLQEEYHLKPET-KTILFVKTR----ALVDALKKWIEENP--ALSFLKPGILTGRGRTNRA--------------------TGMTLPAQKCVLEAFRAS---------GDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGRARDSKCFLLTSS-ADVIEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KANMIKEKIMNESILRLQTWDEMKFGKTVHRIQVNEKLLRDSQHKPQPVPDKENK----KLLCGKCKNFACYTADIRVVETSHYTVLGDAFKER---FVCKPHPKPKIYDNFEKKAK--------------IFCAKQNCSHDWGIFVRYKTFEIPVIKIESFVVEDIVSGVQNRHSKWKDFHFERIQFDPAEMSV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKW7-1", "uniprot_id": "A0A8I6GKW7_RAT", "id": "A0A8I6GKW7-1", "name": "Antiviral innate immune response receptor RIG-I", "aln": "---------------------------------------------------------------------------------------------------MTAEQRQNLQAFRDYIKKILDPTYILSYMSSWLRDDEVQCIQAEKNNKGPIEAASLFLR------------------------------YLLELQTEGWFRAF----LDALYHAG--YCGLYEAIETWDFQKLEKLEEHRLLLRRLEPEFKATVSPTDILSEISECLINQECEEIRQICFTKGRMAGAEKMVQCLLR--SDKENWPKVLQFALEKDNSKFSELWLVDK----GVRRVDCKAVEDDGTEMASIQIF----------------------IQEEPECQNLSQNPGPPSEASPNNSHSP--------------------------------------------------------LKPRNYQLELALPAKKGK-----------------------------------------------------NTVICAPTGCGKTFVSLLICEHHLKNFPH-------------------------GQKGKVVFFAN-----QIPVYEQQATVFSRYFER-FGYNVAGISGATADNVSVQHIIENNDIVILTPQILVNS--------------------------------------------------------------------------------------------LNNGA-----IPSLSVFTLMIFDECHNTSKHHPYNQIMFR----------------YLDHKLGGS---------------PDPLPQVIGLTASVGVGDAKTVEEAMLHICKLCAA-------------------------------------------------------------------------------------------------------LDASVIATVRDNVEELEQVVYKPQKISRKVESRASNTFKCIISQLMREAERLAKNVSEELGKF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FQIQNREFGTQKYEQWIVAVHKACTVFQMPDKDEE-----------------------------SRICKALFLYTSHLRKYNDALIISEDAQ-------------------MKDALNYLKAFFHDVREAAFDETE-------------------------------QDLTRRFEEKLEELENVSRDPSNENPKLRDLYLILQEEYHLKPET-KTILFVKTR----ALVDALKKWIEENP--ALSFLKPGILTGRGRTNQA--------------------TGMTLPAQKCVLEAFRAN---------ADNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARDSKCFLLTSS-ADVIEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KANMVKEKIMNESILRLQTWDEVKFQKTVHRIQLDEKLLRDSQHKPQPVPDRENK----KLLCGKCKTFACYTADIRVVEKSHYTVLGDAFKER---FVCKPHPKPKIYDSFEKKAK--------------IFCAKQNCSHDWGIFVRYKTFEIPVIKIESFVVEDIESGVQNRHSKWKDFHFERKQFNPEEMST----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95786-1", "uniprot_id": "RIGI_HUMAN", "id": "O95786-1", "name": "Antiviral innate immune response receptor RIG-I", "aln": "---------------------------------------------------------------------------------------------------MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLK------------------------------FLLELQEEGWFRGF----LDALDHAG--YSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIPTDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLR--SDKENWPKTLKLALEKERNKFSELWIVEK----GIKDVETEDLEDK-METSDIQIF----------------------YQEDPECQNLSENSCPPSEVSDTNLYSP--------------------------------------------------------FKPRNYQLELALPAMKGK-----------------------------------------------------NTIICAPTGCGKTFVSLLICEHHLKKFPQ-------------------------GQKGKVVFFAN-----QIPVYEQQKSVFSKYFER-HGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNN--------------------------------------------------------------------------------------------LKKGT-----IPSLSIFTLMIFDECHNTSKQHPYNMIMFN----------------YLDQKLGGS---------------SGPLPQVIGLTASVGVGDAKNTDEALDYICKLCAS-------------------------------------------------------------------------------------------------------LDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEE-----------------------------SRICKALFLYTSHLRKYNDALIISEHAR-------------------MKDALDYLKDFFSNVRAAGFDEIE-------------------------------QDLTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHLNPET-ITILFVKTR----ALVDALKNWIEGNP--KLSFLKPGILTGRGKTNQN--------------------TGMTLPAQKCILDAFKAS---------GDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSN-AGVIEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIRDSQEKPKPVPDKENK----KLLCRKCKALACYTADVRVIEECHYTVLGDAFKEC---FVSRPHPKPKQFSSFEKRAK--------------IFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEMSK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40562-1", "uniprot_id": "MPH1_YEAST", "id": "P40562-1", "name": "ATP-dependent DNA helicase MPH1", "aln": "-MASADDYFSDFEDDELDKLYEKAINKSVKETITRRAVPVQKDLHDNVLPGQKTVYEEIQR---DVSFGPTHHELDYDALSFYVYPTNYEVRDYQYTIVHKSLFQNTLCAIPTGMGKTFIASTVMLNYFRWTKKAKIIFTAPTRPLVAQQIKACLGITGIPSDQTAILLDKSRK-NREEIWANKRVFFATPQVVENDLKRGV----LDPKDIVCLVIDEAHRATGSSAYTNVVKFIDRFNSSYRLLALTATPASDLEGVQEVVNNLDISKIEIRTEESMDIVKYMKKRKKEKIEVPLLLEIEDIIEQLGMAVKPVLQQAIELGIYEECDPSQINAFKAMQQSQKIIANPT----------------------------IPEGIKWRNFFILQLLNNVGQMLKRLKIYG--------------------------------------------------IRTFFNYFQNKCTEFTTKYN-------------------------------------------------------LKKSTNKIAAEFYYHPILKNIKNQCEN-------------------------YLSDPKFVGHG-----KLQCVRDELMDFFQKRGS-DSRVIIFTELRESALEIVKFIDSVADDQIRPHIFIGQAR-------------------------------------------------------------------------------------------AKEGFDEVKYTRKHAPKGRKKVERLHRQEQEKFLEAERTK----------------RAANDKLER-----------------SARRTGSSEEAQISGMNQKMQKEVIHNFK-KGE-------------------------------------------------------------------------------------------------------YNVLVCTSIGEEGLDIGEVDLIICYDTTSSPIKNIQRMGRTGRKRDGKIVLLFSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NESYKFERAMEDYSTLQALISKQCIDYKKSDRIIP---------------------------------------EDIIPECHETLITINDEN---------------------EIINEMEDVDEVIRYATQCMMG----------------------------------------KKVKPKKAITKKKRVQENKKPKKFFMPDNVETSIVSASTLIN------------KFLVNESGGKQLVTSNENPSKKRKIFKALDN----------------------LENDSTEEASSSLETE---------DEEVSDDNNVFIAEGQNGCQKDLETAIIRTGESLTTLKPLHNFERPNMALFVNDCGLPTKIEKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKDIRGNQHNLEKEKSCTVDKNNMVLSLDDWNFFRNRYIPEG-----------------VSFDVEPNFVQYTKGVKVPHCHKVSKIITLFNDE---SNDNKKRTIDMNYTKCLARG------------------------MLRDEKKFVKVNDKSQVDNNSVNHDSSQSFTLSNAELDDILGSDSDF-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDA0-1", "uniprot_id": "FANCM_DROME", "id": "Q9VDA0-1", "name": "DEAD-box ATP-dependent DNA helicase Fancm", "aln": "-------MDVNWMDDDED--------------------------LVAALAMHEEQKSEDADGTRWEHCDEACDGFDMATGHNWIYPNNLPLRSYQQTIVQSALFKNTLVVLPTGLGKTFIAAVVMYNFYRWYPKGKIVFMAPTRPLVSQQIHASQKIMPFPSEDTVQLTGQLPRPKRAELWASKRVFFATPQVVHSDMLEADGECSFPFGSIKLIVVDEAHRAKGRYAYTQVADCLMARNRYFRMLALSATPGRTMEDVAAVCRNLYISNLQVRWDTSIDVQPYIHRRTIRTIVVSLKERIKEPRERLLQIIEPYLRQLMEAEIFKG-NKGTVSRNSLLFEQKSFVERSAQGQRHPDHNIIMGNFAMCISMYHSLDLMERHGLRVFVNNFDADDDGREKFVLARDGNLRN-----LVEQVRQELGANPLDYTTHAMTNGEVPPLPSDLDFGHAKYEKLRQVLVQHFQANPDSRAIVFCEYRESVMLIHRLLLQHRPVLRPRCFVGQGSTVG---------ASYALTQKQQLQIMTDFRSGTSNVLVATSIGEEGLDVGEVEMIVCFDICSTNPTRFIQRIGRTGRKKNGEVVMLVTEGREQQVLKDVLANKDQINKKLLNSSVVKLSLYEQNPRMVPSKFQPKCEEKHMEPVAEEKPKPKSAAKTKESRKRKQPVAQTGSLRKYFKESPPTESQQGILQGIKPYQMSEASQQLVKQQVLRRSVTLKNFFGESQASSTLTSSQEDVQRLRKLTRLLQSSKPFVSDSKDLMSHLQDDHLPRQIKLYLLKSNPEFLRETHLKMQVQSELNIADDRLNSRQRRTKNNYQLLLDICDGMDQMNELLQGDNSGAEISFRDELNPIYNQSPKKFDTICEQIFDGLNEHGLNSNNFELKQDLLEKLELRN-------------------------------------------------------LETTVNEQLGGIEASWSEEEWDQQEEDVKFESMYLSQQLNLPDANVVPHSSTPLRVKPLSKLMFKTLQGDIEEEYHSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEASELGDNLGRLNSLMNASESKIKATERIAPIPVVDSTIETN----------------------------------HFPAVEESQRSTPISIADSSGESNHCAVNK---NSEIYPMSIDETKVEVKSSLNLKMHAESIVEDLDIDLDDFLEPMDKELELASQTKGKSQENIVDHQMEKLEKNCEQKETAHNNDLDLTDEDLKEFLEPMVEEVELMSQKKANDFKDFLEPMPEELELMSQQKKNILLPSTETIKNSENKNSHEDGSRTVSPDIFGSDSMSPLKPQGKSLAAKLAAKAAAKVLPCPPPNSVGLNSPENRKRTNPSIQEKSPSIFDLYLNRMRGRGRLAKAAENLHRITSTNPTISVPKDEEDSPIARRPSKRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVISSDEEEEQKPQIAETQVDCESDDYERILDTQMPDPRKTPTRPRHKRSKFNSFILDEAEKSGSDHEEEGETTIGTYLKDSMIVSSDDEDHNDTNTHAIYLRALKSPIQRPGAFKMPPPRVFRDESHIFSQPVEDDSSQYMQCSFIVDDESSTIERGHDVSECPLEKAERILKERRKQRRLGKVPSAPVNKRRRLQTISTSSDEDDVVLID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : : : : . .. : . : .: : . : * . . : . . . : . : . . . : . : . : . : . . . : : . . . ", "identical_positions": 1, "similar_positions": 45, "identity": "0.05%" }, { "cls_id": "homologset.agr.SGD:S000001444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN49-1", "uniprot_id": "RBMX2_RAT", "id": "B0BN49-1", "name": "RNA-binding motif protein, X-linked 2", "aln": "MNPLTKVKLINELNEREVQLGVA-EKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTVLAVDNFNGIKIKGRTIRVDHVANYRAPQESEDVDDVTRELQEKGCGAKTPPSSPPEVSEDEDAKVTKKPKKDKKEKK-KKKEKEKTERPVQAELPSCS--RSKTVKET-DEQSAKKHSSKPSERAQKSECRERKKSHSGSPDGRTSCRGRAEEPEWEAKKEKHKHEHKPSSRREG-EEKSRDKDRGRSSGTHSSRHHGHSEGRSHRSRSRSRSRSPDRSHRHKKHRYSHERESFHASDRRHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0F5-1", "uniprot_id": "RBMX2_MOUSE", "id": "Q8R0F5-1", "name": "RNA-binding motif protein, X-linked 2", "aln": "MNPLTKVKLINELNEREVQLGVA-EKVSWHSEYKHSAWIFVGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTVLAVDNFNGIKIKGRTIRVDHVSNYRAPQESEDVDDVTRELQEKGCGVKTPPSSPPEVSEDEDAKLTKKHKKDKKEKK-KRK-KEKTEGQAQAEQPSCS--RSATVKEKKDERASRKHSSKTSERAQKSEHRESKKSHSGSPDGRSSYHARAEDPECKARKEKPKHEHKSASRREA-EEKSRERERGRSSGTHSGRHRGHSDGRSHRSRSRSRS--PDKSHRHKKYRHSRERDSYHGSDRRHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y388-1", "uniprot_id": "RBMX2_HUMAN", "id": "Q9Y388-1", "name": "RNA-binding motif protein, X-linked 2", "aln": "MNPLTKVKLINELNEREVQLGVA-DKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDE--KPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEK-DDTGPKKHSSKNSERAQKSEPREGQK----LPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRD----KSHRHKRARRSRERESSNPSDRWRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIS0-1", "uniprot_id": "Q9VIS0_DROME", "id": "Q9VIS0-1", "name": "RNA-binding motif protein, X-linked 2", "aln": "MNPLTNMKNVLKLSEHELQHG---GKKSWHDMYKDSAWIFVAGFPYTLTEGDLVCVFSQYGEVVNINLIRDSKTGKSKGFCFLCYEDQRSTVLAVDNLNGIKILDRTLRVDHVADYKPPKENEKMDEETLRLYMEGCAPKPQ------------LQHIKTEKKDSKNYR---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40565-1", "uniprot_id": "IST3_YEAST", "id": "P40565-1", "name": "U2 snRNP component IST3", "aln": "MN------KIQQINDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTF-YRPKRSLQKYYEAVKEELDRDIVSKNN------------AEKLILAKKDQPN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ::.::*:* * : ***. **..*:*::..: *****:: ***:** *:: * **.:**:*:**.:* *******:*****:**:** .*::::**. *:. :. :. : . . .. : : ***. : ", "identical_positions": 55, "similar_positions": 52, "identity": "16.47%" }, { "cls_id": "homologset.agr.SGD:S000001445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96D71-1", "uniprot_id": "REPS1_HUMAN", "id": "Q96D71-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "-----------------------------------------------------MEG--------------LTLSDAEQKYYSDLFSYCDIESTKKV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLP-----------------------------------------------------------------------------------------------RFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQP-RTSADAQ-EPASPVVSP-QQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIE------------------IRRQSSSYDDPWKITDEQRQYYVNQFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIQPDLNGFIPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLD------------------------------------------------------------------------EFCAAFHLVVARKNG------------------------------------------------YDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSE--------------QWETFSERSSSSQTLTQFD------------------------SNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNT--------VADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPD---NTAPPPPPPRPQPSHSRSSSLDMN---------------RTFTVT--TGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPE------------------------------------------------VLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEER-----ISLEVQLEQLRPFSHL-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LDV5-1", "uniprot_id": "A0ABK0LDV5_RAT", "id": "A0ABK0LDV5-1", "name": "", "aln": "-----------------------------------------------------MEG--------------LTLSDAEQKYYSDLFSYCDIESTKKV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLP-----------------------------------------------------------------------------------------------RFVASKNEQESRHAASYSSDAENQSAYAGVIPPPPGRGQVKKAPGSHDAAQP-RPSADQQ-EPASPVVSP-QQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSALLTMHPASVQDQTTVRTVASATTANE------------------IRRQSSSYDDPWKITDEQRQYYVNQFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIQPDLNGFIPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLD------------------------------------------------------------------------EFCAAFHLVVARKNG------------------------------------------------YDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYPGSPAEAPPSKSPSMPSLNQTWPELNQSSE--------------QWETFSERSSSSQTLTQFD------------------------SNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRSSGDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNT--------VADGYSSSDSFPSDPEQIGSNGARQRSHSGASPD---NTAPPPPPPRPQPSHSRSSSLDMN---------------RTFAVA--TGQQQAGVVTHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPE------------------------------------------------VLPAEKASDPSSSLRVAQADSKIEEKTAAGVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEER-----ISLEVQLEQLRPFSHL-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B7S1-1", "uniprot_id": "A0A8M2B7S1_DANRE", "id": "A0A8M2B7S1-1", "name": "", "aln": "-----------------------------------------------------MES--------------LTLSDVEQKYYSELFLSCDVDNAKKV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASNGKVLELFRAAQLSNEVVLQITELCGATRLGHFGRSQFYIALKLIALAQSGLPLRLESLNTVRDLPLP-----------------------------------------------------------------------------------------------RFVMGKNEQETRHMVMFT-DAENQG---PFLPRPPGRVQAKKVS-AHEMIQPCVPTADPQPDTTSPVVSP-HQSPPTSPLAWRKHKRQASGGNVDRQPSVPGVVWPHFREAQPGPVPGDGMWSAHSPPPVQESWVSFTDTPPSSTLPMHPPSAQTESSTVRTVPSAMTTNE------------------IQRQTSGYDDPWKITDEQRQYYINQFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIQADLTGLIPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLD------------------------------------------------------------------------EFCAAFHLVVARKNG------------------------------------------------YDLPEKLPESLMPKLIDLDDSAGVPEPAPEVGFSASPVEVTPNKSPSMPSLNQNWPELNQSNE--------------QWETFSERSSSSQTLTQFD------------------------SNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTHPTSPLMTKPPELSDETKLAAAIKFP-GTA--------VGDGYSSSDSFTSDQEPISSAVNRQRSHSGTSPEGLKVVAPPPPPPRPHASHSRSSSLDMN---------------RNFAAVPAAGSQQAGVVAFPPAVPPRPLPTQTSVPHGHRSVEGDGLPAHTSTSPQQMPEQPNFADFSQFKAFAVDQPADDGENPSDGG----------------------------------------------------QAERLPEAAGTMRTAKNDVQAEERNAT--TVNSAKVSTPLAPPPKPVRRRLKSEDELRPDVDDLPQKSN-VIATVLATQPSIPRSLGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDLLEER-----ISLEVQLEQLRPFSHL-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8NFH8-1", "uniprot_id": "REPS2_HUMAN", "id": "Q8NFH8-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "-----------------------------------------MEAAAAAAAAAAAAAAAGGGC--GSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIK--CELPLP-----------------------------------------------------------------------------------------------RFMMSKNDGEIRFGN--------PAELHGTKVQIP------YLTTEKNSFKRMDDEDKQQ-ETQSPTMSP-LASPPSSPPHYQRVP--LSHGYSKLRSSAEQMHPAP-YEARQPLVQPEGSSSGG----------------PGTKPLRHQASLIRSFSVERELQ--------------------------DNSS-YPDEPWRITEEQREYYVNQFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLQPDPSSFISG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVAKNFFTKSKLSIPELSYIWELSDADCDGALTLP------------------------------------------------------------------------EFCAAFHLIVARKNG------------------------------------------------YPLPEGLPPTLQP-----------------------------------EYLQAAFPKPKWDCQ--------------LFDSYSESLP-ANQQPR---------------------------DLNRME-KTSVKDMADLPVPNQDVTS-DDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSR---------------SYSSTS--------IEEAMKR-------------GEDPPTPPPRPQKTHSRASSLDLN---------------KVFQPS--VPATKSGLLPPPPALPPRP-------------------CPSQSEQVSEAELLPQLS-------------------------------------------------------------------------------RAPSQAAESSPAKKDVLYSQP------------------PSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQER-----IALENQLEQLRPVTVL-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AED1-1", "uniprot_id": "A0A8I6AED1_RAT", "id": "A0A8I6AED1-1", "name": "", "aln": "-----------------------------------------------------MEVAAGGGG--GAG-PPLLLSDSEQQCYSELFARCAGAASGGPGPGPLEATRVAPGILT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAGLPVRTESIK--CELPLP-----------------------------------------------------------------------------------------------RFVMSKNDAEMRVGN--------PAELHGTKVQIP------YLTSEKNSFKRLDDEEKQQ-ETPSPRMSP-LASPPSSPPHYQRVP--LSHGYSKLRSGTEQMHPAP-YESRQPIGQPEGPSSEG----------------PGTKPFRRQASLIRSFSVERELQ--------------------------ENNSNYPDEPWRITEEQREYYVNQFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLQPDPSSFISG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVAKNFFTKSKLSIAELSYIWELSDADCDGALTLP------------------------------------------------------------------------EFCAAFHLIVARKNG------------------------------------------------YPLPEGLPPTLQP-----------------------------------EYLQAAFPKSKWECV--------------IFDSYSESMP-ANQQSC---------------------------DLNRME-KTSVKDMADFPVSTQDVTTGDDKQALKSTVNESLPKDVSEDTATSKDCNSLKARPRSR---------------SYSSTS--------IEEAMKR-------------GEDPPTPPPRPQKTHSRASSLDLN---------------KVFQPS--VSAANSGLLPPPPALPPRP-------------------CPTQAEPASEADLYPQMN-------------------------------------------------------------------------------RAPSQAAESSPTKKDVPHAQP------------------PSKPIRRKFRPENQTTEGQESAAVVGGAAPAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQER-----IALENQLEQLRPVTVL-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B9B6-1", "uniprot_id": "A0A8M2B9B6_DANRE", "id": "A0A8M2B9B6-1", "name": "", "aln": "-----------------------------------------------------MDPGSAGG-------TFMSLSDTEQRCYSGLYALCQPDSSGIP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAGKVAELFRASQLPAETLHQVMEVCGAKRLGFFGCGQFYAALKLLAAAQAGLPVRLESIA--GELPLP-----------------------------------------------------------------------------------------------VFVGITNELDTRYANHLSTSESQPHTLGSVPASAP------RPPTDRAVLRHPDTSMDKQ-EAWSPPRSPPSISPPRSPSAYR------SLTYSAQRNGTDTLLAYDGKMPGRPSVPQENASPGH----------------YSFKLQPEQPSITRVASVERLVE--------------------------RVEVDYSDDPWRITEEQREYYTNQFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLQPDLNALIMG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVAKNFFTKSKLPIPELSHIWELSDVDKDGALTFP------------------------------------------------------------------------EFCTAFHLIVARKNG------------------------------------------------YLLPETLPASLRPGFQ-------------------------------EPVVTAAPSEATQPLI--------------VFDDN--MMPGANQLEIGS------------------------VDLQVTS-RPGVTTKQDTRDESRKPEISPKRVPEPHEKPMQRVSALKPDSPQELDAN-MKSRTRPR---------------SYSSTS--------IDDAMKK-------------VEEPPTPPPRPQKSHSRASSLDLN---------------KLLQQG--TPGAKSGWLPPPPALPPRPPATQIF-----------SFLPGLEKSSQKAVQQPNFADFSRFREEQESGV------------------------------------------------------------------RAGLSTEDLLPPKSDCSLVHQGHA---------------PQKPMRRKLHPESQS----ATPPLTTPYSAATLTKPT---QRPPPKQKREIQMAIRKNRETNAVLTRLNSELQQQLKVVHGER-----LTLETQLESMRPVAST-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WVE9-3", "uniprot_id": "ITSN1_RAT", "id": "Q9WVE9-3", "name": "Intersectin-1", "aln": "----------------------MAQFPTPFGGSLDIWAITVEERAKHDQQFQSLKP-ISGFITGDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALPPVMKQQPAAISSAPA-FGIGGMAGMP---PLTAVAPVPMG----SIPVVGMSPPLVSS--VPQAAVPPLAN--GAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQS-FDVASAPAA---------------AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSADQRLPEEPSSEDEQQ-VEKKLP-VTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQEGIVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLREQLDEVEKETRSKLQEIDVFNNQLK---------------------------ELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQERDKQWQEHVQQE-EQQRPRKPHE----------EDKLKREDSVKKKEAEERAKPEVQDKQSRLFHPHQEPAKPA-QAPWPTTEK---GPLTISAQESAKVVYYRALYPFESRSHDEITIQPGDIVMVD-----ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEIPTPAKPVTDLTSAP---------------APKLALRETPAPLPVTSSEP---------STTPNNWADFSSTWPS-STNEKPETDNWDTWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISG-PVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGE-------------EFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGTVGETSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEL--PKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLS--KEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVND-LQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGS-SSTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSN---CQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0R4-1", "uniprot_id": "ITSN1_MOUSE", "id": "Q9Z0R4-1", "name": "Intersectin-1", "aln": "----------------------MAQFPTPFGGSLDVWAITVEERAKHDQQFLSLKP-IAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSTLPPVMKQQPVAISSAPA-FGIGGIASMP---PLTAVAPVPMG----SIPVVGMSPPLVSS--VPPAAVPPLAN--GAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQS-FDVASAPPA---------------AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSVDQRLPEEPSSEDEQQ-PEKKLP-VTFEDKKRENFERGSVELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEGTVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLREQLDEVERETRSKLQEIDVFNNQLK---------------------------ELREIHSKQQLQKQRSLEAARLKQKEQERKSLELEKQKEDAQRRVQERDKQWLEHVQQE-EQPRPRKPHE----------EDRLKREDSVRKKEAEERAKPEMQDKQSRLFHPHQEPAKLATQAPWSTTEK---GPLTISAQESVKVVYYRALYPFESRSHDEITIQPGDIVMVD-----ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPTPAKPVTDLTSAP---------------APKLALRETPAPLPVTSSEP---------STTPNNWADFSSTWPS-SSNEKPETDNWDTWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISG-PVRKSTSIDTGPTESPASLKRVASPAAKPAIPGE-------------EFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEL--PKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLN--KEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVND-LQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGS-SGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSN---CQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15811-1", "uniprot_id": "ITSN1_HUMAN", "id": "Q15811-1", "name": "Intersectin-1", "aln": "----------------------MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKP-ISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPA-FGMGGIASMP---PLTAVAPVPMG----SIPVVGMSPTLVSS--VPTAAVPPLAN--GAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQS-FDVASVPPV---------------AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLP-VTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLK---------------------------ELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHE----------EEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEK---GPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAP---------------APKLALRETPAPLAVTSSEP---------STTPNNWADFSSTWPT-STNEKPETDNWDAWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISG-PIRKSTSMDSGSSESPASLKRVASPAAKPVVSGE-------------EFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEP--PKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLN--KEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVND-LQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGS-SGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSN---CQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIP7-1", "uniprot_id": "A0A8M2BIP7_DANRE", "id": "A0A8M2BIP7-1", "name": "Intersectin-1", "aln": "----------------------MAQFPTPFGGGSDTWVISVDERAKHDQQFHSLTPTPAGFITGDQARNFFLQSGLPAPILAQIWALADMNNDGKMDMHEFSIAMKLIKLKLQGHPLPPSLPPSMKQQPISIPPPTP-FGIPSMGAMP---GLPAVPPMPLPPLPPGVPGMGVSPPLGAS--VTPP-VPSLAN--GAPAMIQPLSGFSHPGAVLNKTPSFNRS------SIKLQKGQS-VEAPSAPAAP------------PPADWAVSQSSRLKYRQLFNSHDKMMSGYLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSGLPLPPLLPPDLIPPTFRRMRSGSGVSVTSMHSTDLRSQEEP--EEEEKEAEKKLP-VTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAALEKEEQERKERERLEQERRRQQELDKQLERQRELERQREEERRKEIERREAAKRELERQRQLEWERTRRQELLTQRNREQENIVLLKARKKTLEFELEALNDKKSQLEGKLQDIRSRLSIQRHEIETTNKTRELRIAEITSLQQQLQESQQWLSRLIPDKQCLNDQLKQVQQNSLHRDSLNSLQRAIEMKESTKQQLKEQLDAVEKETRSKLLEIDAFNTQLK---------------------------ELREIHNKQQRQKQKELEAD-ITQPSHDRKSIDSQDS------RLSGTDDGVSPAWRDDGLGKAPTPPVS----------QAWMSRVS-----EEENHSRAEIQDNLSKLFTQHPQAGKIQAQSPWSMADK---IPVSGFNQEKVKVVYYRAMYPFEARSHDEITIHPGDIVMVKGEWVDESQTGEPGWLGGEIKGKTGWFPANYAEKIPESEVPLSLRASAASSSAPKLGSHMSSASSSTTATPILPVSTEPASIAPPSSAPPPTGPASSSSSASSNWADFSTTWPSNSAVEKQDSDGWDAWPTQPTQPSLSVPSGGQIRQRSAFTPATLSGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQRGWFPKSYVKLISG-PVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEYVAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSGKIGVFPSNYVKPKESEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPSTSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLS--REDPDWWKGELNGSVGLFPSNYVKLTTDTDPSQQWCADLHLLDMLTPVERKRQGYIHELIVTEENYVND-LQLVTETFQKPLLESDLLTEKEVAMIFVNWKELTMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPEFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRLALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGS-SGTDKVFSAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKRKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSNGKSNPYCEVTMGSQCHVTKTLQDTLNPKWNSN---CQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQGSKGPITKRLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AMD2-1", "uniprot_id": "A0A8I6AMD2_RAT", "id": "A0A8I6AMD2-1", "name": "", "aln": "---------------------MMAQFPTAMNGGPNMWAITSEERTKHDKQFDNLKP-SGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIHQPLPPVAPITAP-LSSATSGTSIPPLMMPAPLVPSVSTSSLPN--GTASLIQPLS-IPYSSSTLPHASSYSLMMGGFG-GASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPSRLKYRQKFNSLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQ--------IDSINGTLPSYQKTQEEEP--QKKLP-VTFEDKRKANYERGNMELEKRRQVLMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKSLHLELEAVNGKHQQISGRLQDVRIRKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLK---------------------------ELRESYNTQQLALEQLHKIKRDKLKELERKRLEQIQK------KKLEDEAARKAKQGKENLWKESIRKEE----------EEKQKRLQ-------EEKSQDRTQE----------EERKTEAKQS----------------ETARALVNYRALYPFEARNHDEMSFNSGDIIQVD-----EKTVGEPGWLYGSFQGKFGWFPCNYVEKMLSSD--KTPSPKKALLPPA------------------VSLSATSAAPQPLCSNQ------------PAPVTDYQNVSFS----------------------NLNVNTT--WQQKSAFTRTVSPGS-VSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKIIPGSEVKRGEPEALYAAVNKKP-------TSTAYPVGE-------------EYIALYSYSSVEPGDLTFTEGEELLVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENVGNASKSGASNKKPEIAQVTSAYAASGAEQLSLAPGQLILILKKNSSGWWQGELQARGKKRQKGWFPASHVKLLGPSAERTTPAFH---------AVCQVIAMYDYIANNEDELNFSKGQLINVMN--KDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQPMERKRQGYIHELIETEERYMDD-LQLVIEVFQKRMAESGFLTEAEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVEMMGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDADFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQNHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLYSGKLYKTKSNKELHGFLFNDFLLLTYLVRQFAASSGFEKLFSSKSSAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTLQDTLNPKWNFN---CQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESKGPTTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0R6-1", "uniprot_id": "ITSN2_MOUSE", "id": "Q9Z0R6-1", "name": "Intersectin-2", "aln": "---------------------MMAQFPTAMNGGPNMWAITSEERTKHDKQFDNLKP-SGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIHQPLPPVAPIATP-LSSATSGTSIPPLMMPAPLVPSVSTSSLPN--GTASLIQPLS-IPYSSSTLPHASSYSLMMGGFG-GASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQ--------VDSVNGTLPSYQKTQEEEP--QKKLP-VTFEDKRKANYERGNMELEKRRQVLMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERLRRQELLSQKTREQEDIVRLSSRKKSLHLELEAVNGKHQQISGRLQDVQIRKQTQKTELEVLDKQCDLEIMEIKQLQQELKEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLK---------------------------ELRESYNTQQLALEQLHKIKRDKLKEIERKRLEQIQK------KKLEDEAARKAKQGKENLWRESIRKEE----------EEKQKRLQ-------EEKSQDKTQE----------EERKAEAKQS----------------ETASALVNYRALYPFEARNHDEMSFSSGDIIQVD-----EKTVGEPGWLYGSFQGKFGWFPCNYVEKVLSSE--KALSPKKALLPPT------------------VSLSATSTSSQP-----------------PASVTDYHNVSFS----------------------NLTVNTT--WQQKSAFTRTVSPGS-VSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGE-------------DYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERTMPTFH---------AVCQVIAMYDYMANNEDELNFSKGQLINVMN--KDDPDWWQGETNGLTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQPTERKRQGYIHELIQTEERYMDDDLQLVIEVFQKRMAEEGFLTEADMALIFVNWKELIMSNTKLLRALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLLLTYLVRQFAAASGHEKLFNSKSSAQFRMYKTPIFLNEVLVKLPTDPSGDEPVFHISHIDRVYTLRTDNINERTAWVQKIKGASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFN---CQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESKGPTTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZM3-1", "uniprot_id": "ITSN2_HUMAN", "id": "Q9NZM3-1", "name": "Intersectin-2", "aln": "---------------------MMAQFPTAMNGGPNMWAITSEERTKHDRQFDNLKP-SGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS--LSSATSGTNLPPLMMPTPLVPSVSTSSLPN--GTASLIQPLP-IPYSSSTLPHGSSYSLMMGGFG-GASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQ--------IDSINGTLPSYQKMQEEEP--QKKLP-VTFEDKRKANYERGNMELEKRRQALMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQK------KKLEDEAARKAKQGKENLWKENLRKEE----------EEKQKRLQ-------EEKTQEKIQE----------EERKAEEKQRKDKDTL---KAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVD-----EKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPT------------------VSLSATSTSSEPLSSNQ------------PASVTDYQNVSFS----------------------NLTVNTS--WQKKSAFTRTVSPGS-VSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGRGWFPKSYVKIIPGSEVKREEPEALYAAVNKKP-------TSAAYSVGE-------------EYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFH---------PVCQVIAMYDYAANNEDELSFSKGQLINVMN--KDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQTLDTMQPIERKRQGYIHELIQTEERYMAD-LQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLFSSKSNAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFN---CQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQESKGPMTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PBV5-1", "uniprot_id": "A0A8M9PBV5_DANRE", "id": "A0A8M9PBV5-1", "name": "", "aln": "-----------------------------MNGGFSIWAITPEERGKHDKQFDSLAP-TLGYLSGDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLPIIMKQTPTPVMTSSSRFGMGSMPNLS----AMSVMPILTP-----IPTCPVMAPLVPVPTLISGPLPQMPNSISVPALPNGNATLLTPTPAFPVSSGLTKSHSLLDLGSSSSNSSSTTSLASNSPKTS------------SSDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTGRPLPLTLPPDLVPPSLRTTKS--------CDLLNGPVPLISTELIEPELPQKNKSNVSYEDKLRENFQRGNAELEKRRLALQEQQRREEERRREEERREEEKRQQKEREERERREREAREMEIRRQREEERRMERQRELERQREEERLKELERRE----EAERQRRREWEKSKRVELQTQKEKEQNDIQRLKDRKRSLEIELEAVGNKHKQISSQLRDAKSKRQGQWAELELINQRRDVCITDINSLQLQFDEMQRQLNQLGPEKQRLADRLVHFTQN-ISSPLINDVKQSVCEKDRSCRKLKEQLDVLERETTAKLSQMEQYNKEIKFVEMDDCVLQGLLSLLGCLTNLFLLIKELRQKQSQQQDVLEQLRRVRSDKLKELQRHRKEEEERK-----RKKEEEAARQAQLEQERLEQEEAERQRKLAQEREAKLREEQQRQALARLLEAQEQARAKEEKRRAEEKERNELDVHTQSSLPFNSTENNILQPVVIPEVTCSSLTTYRALYPFTARNSDELTLEADCFIQVD-----ESTVRETGWLYGSYSGNRGWFPESYAERCSKDSQTQPTAAETESTAPS--------------------------------------------------------------------------------------------ANYPGIPRVDIEGPTPTHTP-VSTNTQHSQAVALCEWSAKTDSHLGFCKDDIITVLEKQENWWYGELKEKRGWFPCSHVSVVTT---NNTQSEPLYSSVEEIEVS--------DSGLLD-------------EYVALYTYESPESGDLTFSAEDVVLVTEKEGEWWRGCIGDQTGLFPSNYVKPKEPDTASSAVPS----KKPEIAQVTTVSPATTPEQLSLTPGQLIVVLHKNSNSWWLGELQARGKKRKKGWFQSSNVRLLEANSGKITPAPQ---------PLCQVIAMYDYKAANKDEMSFQKGQLITVLN--KDNPDWWKGEVAGVTGLFPTNYVKMTTECDPSQQWCADLLSLDSMCTEERKRQGYIHELIQTEESYLED-LELAVEVFYKPMAESGRLTEAEISMIFVNWRELIMCSTKLLKALRVRKKTAGERMPVQVVGDILSSELSHMQAYIRFCSCQLNAAALLQQKTDKSLDFKLFLKKIASNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPPAHADHSNLQAALEQAEELCSQVNEAVREKENSDRLEWIQNHVLCDGVIEHLVFNSLTNCLGPRKLLHSGKLHKTKSSKELWALLFNDFLLLTYTSKQFSS--SPDKLFNPNSNTQYKMYKTPVFLNEVLVKMPSDPSSDDPVFHISHIDRVYTLKTDTINERTTWVQKIKAASDHFIETEKLKREKAYQARSQKNSGIGRLLVTVLEATELKPCKPNGKSNPYCELTMGAQCYTSRHQPDTLNPKWSFN---CQFFIKDLYQDVLCLTVFERDQFSPDDFLGRTEVPVATIKKDQDGKGPLVRRLLLHEVPTGEVKVRLDLQLYEQTPHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32521-1", "uniprot_id": "PAN1_YEAST", "id": "P32521-1", "name": "Actin cytoskeleton-regulatory complex protein PAN1", "aln": "MYNPYQQQGMGYQQQQQQQQQQPNGFYPQQQQGQSSNQPQGQPQPQQQMAFNQPQATGIGGMPQSFGNSFSSMPQQPQTGYNNNGNNGSVYGNGNFGQQPQQQQQQAKPQHTGYVPNSSMPMMNTTGTMPPPNPAQQPQLQSIQPQGTGYYQAANTANVHSVQPLQSQGTGYYVSTPNLISSNQTQQPLQAQGTGYYQSQPQQVPPPQQAQSLQPLKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNG--LNNDIKIPAIRLSFITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYELDSKTKNEVSSFIDAIN---------------------------------LSIANQDSSANDAPKTPFDEFITAGVQNLQPQPTG----------------YMPQTSFGIPLQSQITGGGVASALNPQSTGFMAPTTFNMSMNTGTPGLNPQITGGAPASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGVNLGPQLTGGALQSQYTGGYGSVMPQQSGPASMPNLSFNQQGLQSQLTGLQPQPTGFLPPSNFSATMPLTAQKTGFGNNEIYTKSN-----------FNNNLIDNSSQDKISTEEKSLFYKIFET------------------------------FDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWN----------------------------------------------------------------------------------------------------------LCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSSTKLLDNLKNQLKTEPTTTKEKPSFGKIDALSYKNNDDDVLPN-------------------------------------------------------------------------------------------------------------------------YRNRRKVYSAKNEEQSSFSSPSAKSVNHSSSTLQTDDISVDKTVEKKTAKPKYAGFSREINLKNIASLENEIKN-------------------------------ISNPENCYDSSIPSDLTSRFDAIIAKLPN--------------LFNEISTIDNEITNAKIQLYRKKNPSSIIGSGPNGEITENDRKKAKSRALLRARMSALTGKSTESEDSLSMEDEQQSAEIKRIQQENGKNQEIIKDIR--------SSISDISASLKSTMTGSNMISNQEFERWEFGIGLEDGVREFLDDLKSNSNKSVTESSPFVPSSTPTPVDDRSSSPSYSQFKTAEERAAYLKEQAKKRMKEKLAKFDKNRRNVTQSSRSISSENSREQPQQIAGSSNLVEPRATPFQEEKYVEVAQPTQPVQSTQPVQPTQPVQPTQPVQPTQPVQPTQPVQPTQPVQNVYNAKQESDDEDEDDEEKRLQEELKRLKLKKKADKEKRLAALRKQIEDAQNESDEEETNGKDNFGGHVNVPQAAPVAPSAAFSQNSTNAPRSVHAAVTPAAGKNSTG--------------------------LPSTTMGHNPYFKDASASSTSTFDARAAEMQRRIQRGLDEDEDDGWSDEDESNNRVAVDNKVEEAKIGHPDHARAPPVTAAPLPSVTPVPPAVPVPQANTSNEKSSPIPIAPIPPSVTQEPPVPLAPPLPAVDGFQEPPIPSAPAIATAVQKSGSSTPALAGGVLPPPPPLPTQQASTSEPIIAHVDNYNGAEKGTGAYGSDSDDDVLSIPESVGTDEEEEGAQPVSTAGIPSIPPAGIPPPPPLP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *. : : :.. * : :* *::* . * .: . . . : . . . . : . : . :. : . * . . .: . . .: : ::. . . . . : . . . . . . . . : . : : .: . . : .. : : : ", "identical_positions": 7, "similar_positions": 71, "identity": "0.37%" }, { "cls_id": "homologset.agr.SGD:S000001447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNK6-1", "uniprot_id": "F1LNK6_RAT", "id": "F1LNK6-1", "name": "DNA primase", "aln": "-------------------MELFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPSQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLIKGG---HDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVDQDILEN-KENWDKILALVP-ETVHDELQKGFQR----FHSSPQRWEYLRKVASAPQN-TKNDKCG---PWLEWEIMLQYCFPRLDINVSKGVNHLLKSPFSVHPKTGRISVPIDFQKVDQFDPFVVPTISAICRELDVVSTTEKEKEENETDS--RHRVRDYKRTSLAPYVKVFEQFLENLDKSRKGALLKKSDLQKDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20664-1", "uniprot_id": "PRI1_MOUSE", "id": "P20664-1", "name": "DNA primase small subunit", "aln": "-------------------MEPFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSELEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGG---QDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVGQDILEN-KENWDKILALVP-ETIHDELQRGFQK----FHSSPQRWEHLRKVANSSQN-MKNDKCG---PWLEWEVMLQYCFPRLDVNVSKGVNHLLKSPFSVHPKTGRISVPIDFHKVDQFDPFTVPTISAICRELDMVSTHEKEKEENEADS--KHRVRGYKKTSLAPYVKVFEQFLENLDKSRKGELLKKSDLQKDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49642-1", "uniprot_id": "PRI1_HUMAN", "id": "P49642-1", "name": "DNA primase small subunit", "aln": "-------------------METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGG---QDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILEN-KESWDKILALVP-ETIHDELQQSFQK----SHNSLQRWEHLKKVASRYQNNIKNDKYG---PWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAISTNEEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24317-1", "uniprot_id": "PRI1_DROME", "id": "Q24317-1", "name": "DNA primase small subunit", "aln": "MPEQVTDQENQAPQQQTTAVHAYNPEVLQDMLPVYYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDTQAELEKEICSRNPIKIDIGPVMHSKPKNHRSIP-GGLTPVQRELVFDIDMTDYDEVRTCCSGAGVCLKCWKFMVLAARVLDVALREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNIITYASFAGGNSPRCSMGDRPHHSLKRALKIVEPMFEEIVLEDQNLFGT-PKGVTKLLNMVHDDAARGELESYMQKNLEDGAHSRLVWESFIKYANSMRTSTTSAWSRK-LKNIVAEIQLGLLYPRLDINVTRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEINAFDDKSKSYMEAPEDK---SRIKDHKKTSMFKGVVVFEEFLRKLERSQKSASLQF-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10363-1", "uniprot_id": "PRI1_YEAST", "id": "P10363-1", "name": "DNA primase small subunit", "aln": "-----------------MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDR----NTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDN--PRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCVPIDES----FAPEKAPKLIDLQTEMEKNNDVSLTALQP--------FINQFQAYVSSLLKNELGSVKREREDDDEPASLDF-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : **: *:*. :.**.:. . : :**::::::.. * ** .*:. ::: :: . ** :::**.: * :: :: . : . ::******** *** .* ***.* :* ***.:: :* :: : **:****::. :*::***** ****.* .* * . * : :*:.:: . . : : * : :::: :: * . * *: . .:* : . ..*: * *: : : *. . .. :: * :*:**::*:: ****:**.:** **.:.**:. * * .*.: : *:: . . : . .: : . .: : . : *. ", "identical_positions": 90, "similar_positions": 134, "identity": "19.96%" }, { "cls_id": "homologset.agr.SGD:S000001448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U214-1", "uniprot_id": "Q5U214_RAT", "id": "Q5U214-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09012-1", "uniprot_id": "SNRPA_HUMAN", "id": "P09012-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62189-1", "uniprot_id": "SNRPA_MOUSE", "id": "Q62189-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------MATIATMPVPETRANHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRIMKMRGQAFVIFKEVTSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTYVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMPQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CQI7-1", "uniprot_id": "RU2B_MOUSE", "id": "Q9CQI7-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAA--------------------------------------------------ANKKPGQGTPNAANTQ----GTAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEQ4-1", "uniprot_id": "B5DEQ4_RAT", "id": "B5DEQ4-1", "name": "", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAA--------------------------------------------------ANKKPGQGTPNSANTQ----GNAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08579-1", "uniprot_id": "RU2B_HUMAN", "id": "P08579-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATT--------------------------------------------------TNKKPGQGTPNSANTQ----GNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GDR2-1", "uniprot_id": "R4GDR2_DANRE", "id": "R4GDR2-1", "name": "", "aln": "---------------------MDIRPNHTIYINNVNDKIKKEELKRSLYALFSQFGQIMDIVALKTMRMRGQAFVIFKELSAATNALRQLQGFPFYNKPMRIQYAKTDSDLVSKMRGTYGDKEKKKEKKK-KAQEQAAAN--------------------------------------------------ANKKP----AGAVNTQ----PPPPATVQIPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGKHDISFVEFESEAQAGVAKDALQGFRITATCAMKITYAKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43332-1", "uniprot_id": "SNRPA_DROME", "id": "P43332-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "---------------------MEMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEIGSASNALRTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTFKERPKKVKPPKPAPGTDEKKD--------------------------------------------------KKKKP----SSAENSN--------PNAQT-EQPPNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPNRHDIAFVEFTTELQSNAAKEALQGFKITPTHAMKITFAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40567-1", "uniprot_id": "MSL1_YEAST", "id": "P40567-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "MVEPARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMN-FKKQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSETKTL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*:*:.::*:**: :.*: .*: :*: **.::.: : *****: :: : :: * ::* *:.**::: ::*:::. : ", "identical_positions": 21, "similar_positions": 43, "identity": "7.0%" }, { "cls_id": "homologset.agr.SGD:S000001451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7V2-1", "uniprot_id": "G3V7V2_RAT", "id": "G3V7V2-1", "name": "Angio-associated migratory cell protein", "aln": "MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEEEEGNDEGWVLEPQEG--VVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG--ELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVETKEE-------VWSFEAGDLEWMEWHP-RAPVLLAGTADGNTWMWKVP--NGDCKTFQG---PNCPATCGRVLPDGK-----RAVVGYEDGTIRIWDLK-QGNPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGE----GEESESNSVESLGFCS---VMPLAAVGYLDGTLAIYDLSTQTLRHQCQHQSG---IVQLLWEAGTAVVYTCSLDGVVRLWDARTGRLLTDYRGHTAEILDFALSK--------DASLVVTTSGDHKAKVFCVQRPDR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13685-1", "uniprot_id": "AAMP_HUMAN", "id": "Q13685-1", "name": "Angio-associated migratory cell protein", "aln": "MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEEE-GNEEGWVLEPQEG--VVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDG--ELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEE-------VWSFEAGDLEWMEWHP-RAPVLLAGTADGNTWMWKVP--NGDCKTFQG---PNCPATCGRVLPDGK-----RAVVGYEDGTIRIWDLK-QGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGE----GEESESNSVESLGFCS---VMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSG---IVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSK--------DASLVVTTSGDHKAKVFCVQRPDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9NE98-1", "uniprot_id": "M9NE98_DROME", "id": "M9NE98-1", "name": "Angio-associated migratory cell protein", "aln": "--------MRDNTPPHRPDFDDGDDELQEIIELEEQPLDEDDDDLEEVTLEQLEARLAMAGGDDDEEEDEEELRDRERIAAITDEATVTFKKHTAPVFACSLHPNYN-WAVTGSEDDRAFVWETSTG--DVLYEITEHKDTVTETHFSHDGVYLATGDLAGDLFVFKVSEKHDERPILTKIWEYSMSDMSWLFWHR-AAHILLAGSDSGEVFVFRIP--SGECKILPG---QSSRCESGELSGDGK-----KLFTAYVNGSVKLWDLKSCQVLIDVNESHPMGFGEITHAVVACERESPFYVCAEASGECSSGKGIRYNTSFHNKTIRKMLFCTNNGPVSTIQSEHGIECLAFAPSSADLKLFACGSLDGRISIWDYAKSALRTICENPVPNDAVIRIKWLN-DHTILAATSQGNLNAFDARTGILKFTLTGHYYHIYEFVYKP--------QENLLLTVSEDNTAKIFKVPALGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35184-1", "uniprot_id": "SQT1_YEAST", "id": "P35184-1", "name": "Ribosome assembly protein SQT1", "aln": "----------MEPQEEFITTEEVEQEIVPTVEVEQDVP---------VDIEGENDDDDEMMNDDEEALEVDMS----------NNSLTYFDKHTDSVFAIGHHPNLP-LVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLAS--QMQEVEEIVWLKTHPTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQDCSMGEFINTDKGENTLELVTCSLDSTIVAWNCFTGQQLFKITQAEIKGL-EAPWISLSLAPETLTKGNSGVVACGSNNGLLAVINCNNGGAILHLSTVIELKP-EQDELDASIESISWSS---KFSLMAIGLVCGEILLYDTSAWRVRHKFVLEDS---VTKLMFDN--DDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFILLHPVANTGTEQKRKVITAGDEGVSLVFEVPN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::*: :*:: :: : .:: : : ::: . * *: .**. . .*: . **. *: *.:* .. : : ::* *: :. :.*.*::* : * . . :: *: * * : *: .*..: ::: .*. : : . . . *.. .* . .. :.:: *: :.: :. . . . . . :: : . . .:*.:.:.. : * * * : * : ::* : :* : :: : : :. :* : ::**** ** : :* : ::*.. : : :* * ", "identical_positions": 45, "similar_positions": 130, "identity": "9.45%" }, { "cls_id": "homologset.agr.SGD:S000001454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R040-1", "uniprot_id": "RPP21_MOUSE", "id": "Q8R040-1", "name": "Ribonuclease P protein subunit p21", "aln": "-----MAGPVKDREAFQRLSFLYQAAHCVLSQNPENQALARFYCHTEKTIAKRLVLRQDPSVKRTLCRSCSSLLIPGLTCTQ------RQRRRKGQRWTVQTCLTCQ-RSQRFLNDPKHLLWGDRPEAQLENQADINPSEP---------------LPN----IAD-LPKENIQTQALNTSE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H633-1", "uniprot_id": "RPP21_HUMAN", "id": "Q9H633-1", "name": "Ribonuclease P protein subunit p21", "aln": "-----MAGPVKDREAFQRLNFLYQAAHCVLAQDPENQALARFYCYTERTIAKRLVLRRDPSVKRTLCRGCSSLLVPGLTCTQ------RQRRCRGQRWTVQTCLTCQ-RSQRFLNDPGHLLWGDRPEAQLGSQADSKPLQP---------------LPNTAHSISDRLPEEKMQTQGSSNQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86B65-1", "uniprot_id": "Q86B65_DROME", "id": "Q86B65-1", "name": "", "aln": "MSRDNKMKHLTQRAISSRMNYLFQASNLMAVGNQPK--LAAYYGKLCRNVGTKAIMHMAPAVKRSLCRRCFLPLIPGVNTELHVEEGAQEAKTDAQAQSNGAVKTKKKRHRRQRKKPRSRKTGNTNQEESEEQIQESTEQVSFFLECSLCCGRRSFAANSQRDCWLEQPQSIVQVVSLPKEKDER", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40571-1", "uniprot_id": "RPR2_YEAST", "id": "P40571-1", "name": "Ribonuclease P protein subunit RPR2", "aln": "--MGKKAHGGKMKPEIDENGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNYIKSMDLIS--------------KKTKTSLLPTIKRTICKKCHRLLWTPKKLEITSDGALSVMCGCGTVKRFNIG---------------ADPNYRTYSEREGNLLNS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. . * .. : * * : : . . : *:. : . . : : . .: . : .: . :: ", "identical_positions": 4, "similar_positions": 30, "identity": "2.16%" }, { "cls_id": "homologset.agr.SGD:S000001461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTR7-1", "uniprot_id": "SC11C_RAT", "id": "Q9WTR7-1", "name": "Signal peptidase complex catalytic subunit SEC11C", "aln": "MVRAGAVGTHLPTSSLDIFGDLRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEK-KDVVGRARGFLPYVGMVTIIMNDYPKFKYALVAVMGAYVLLKRES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8V7-1", "uniprot_id": "SC11C_MOUSE", "id": "Q9D8V7-1", "name": "Signal peptidase complex catalytic subunit SEC11C", "aln": "MVRAGAVGTHLPTSSLDIFGDLRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEK-KDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY50-1", "uniprot_id": "SC11C_HUMAN", "id": "Q9BY50-1", "name": "Signal peptidase complex catalytic subunit SEC11C", "aln": "MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEK-KDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0P6-1", "uniprot_id": "SC11A_MOUSE", "id": "Q9R0P6-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "------------MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42667-1", "uniprot_id": "SC11A_RAT", "id": "P42667-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "------------MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMLITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFSYAVLFLLGLFVLVHRE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67812-1", "uniprot_id": "SC11A_HUMAN", "id": "P67812-1", "name": "Signal peptidase complex catalytic subunit SEC11A", "aln": "------------MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEK-KDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7V7-1", "uniprot_id": "SC11B_HUMAN", "id": "P0C7V7-1", "name": "Putative signal peptidase complex catalytic subunit SEC11B", "aln": "------------------------MNKWRLYYQVLNFGMIVSSALMIWKGLMVITGSESP-IVLLSGSMEPAFHRGYLLFLTNRVEDPIRVGEIAVLRIEGRKIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQDQHWLEK-KDVVGRARGFVPYIGIGTSLMNDYPKHKYEVLFLLGLFVLVHRE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97066-1", "uniprot_id": "O97066_DROME", "id": "O97066-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "------MGVASMLQIDEMLGDFNRMNKRQSLYQVLSFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEPVRVGEIVVFKVEGRDIPIVHRVIKLHEKEDGSVKFLTKGDNNNVDDRGLYAPNQLWLTK-KDIVGRARGFLPYVGIITIFMNEYPKVKWAILSILAIFVLLHRE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15367-1", "uniprot_id": "SEC11_YEAST", "id": "P15367-1", "name": "Signal peptidase complex catalytic subunit SEC11", "aln": "------------------------MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNR-NTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ::*.. ::.:** *:*:** : *.* ** :*:*********:** :*** * : :.*::.* .:**:.*******:: *::. . :******* :* .** : :* * *::** .:*:.* :* * :.: .: :: ::. .*: * ", "identical_positions": 62, "similar_positions": 56, "identity": "32.12%" }, { "cls_id": "homologset.agr.SGD:S000001465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0T2-1", "uniprot_id": "DUS12_MOUSE", "id": "Q9D0T2-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEAQGSNHGCERQAPTASPASSAG------------HAVEVRPGLYLGGAAAVAEPGHL-REAGITAVLTVDSE-PAFPAGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIG-----------------QARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTFEKAYDILRTVKPEAKVNEGFEWQLKLYEAMG-YEVDTSSAFYKQYRLQKVTEKCPKLWNLP------QELFAVDPTT--ISQGLKDDILYKCRKCRRSLFRHSSILGHS---------------------------------EGSGPIAFAHKRTAPSSVLTTGSQAQ----CTSYFIEPVQWMESTLLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEMKMLPVLGSQTKKL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JIM4-1", "uniprot_id": "DUS12_RAT", "id": "Q9JIM4-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEVQSSNHGCERQAPTTSPASSAG------------HAVEVRPGLYLGGAAAVAGPDYL-REAGITAVLTVDSE-PAFPAGAGFEGLQSLFVPALDKPETDLLSHLDRCVAFIG-----------------QARSEGRAVLVHCHAGVSRSVAVVTAFIMKTEQLTFEKAYENLQTIKPEAKMNEGFEWQLKLYEAMG-HEVHTSSAVYKQYRLQKVTEKYPELRNLP------RELFAVDPTT--VSQGLKDDILYKCRKCRRSLFRRSSILDHS---------------------------------EGSGPVAFAHKRTGLSSVLTTGNQAQ----CTSYFIEPVQWMESALLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEVKTLPALGSQTKKP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNI6-1", "uniprot_id": "DUS12_HUMAN", "id": "Q9UNI6-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEAPGPSDGCELSNPSASRVSCAG------------QMLEVQPGLYFGGAAAVAEPDHL-REAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIG-----------------QARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMG-YEVDTSSAIYKQYRLQKVTEKYPELQNLP------QELFAVDPTT--VSQGLKDEVLYKCRKCRRSLFRSSSILDHR---------------------------------EGSGPIAFAHKRMTPSSMLTTGRQAQ----CTSYFIEPVQWMESALLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYI8-1", "uniprot_id": "F1QYI8_DANRE", "id": "F1QYI8-1", "name": "Dual specificity protein phosphatase 12", "aln": "--------------------------------------MIPVASGLYIGSVSDLKDAESL-SAAGITHILTVDSE------EASVTGFNTKFIRALDDESTDLLSRLDDCTSFISEALST------------QADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMD-CKVDTTSPVYKQFRLKKITEKYPELQNVP------KDVFAVDP-----AQTQNAEAVYRCRKCRRTLFRHSSILSHC---------------------------------VGSGASAFSHKKTRIVSS-SAEDETQ----CTSYFIEPVQWMEQALLG--VMDGQLLCPKCSSKLGSFNWY-GEQCSCGRWVTPAFQMHKNRVDEIKHISISALK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWF4-1", "uniprot_id": "DUSK4_DROME", "id": "Q9VWF4-1", "name": "Dual specificity protein phosphatase MPK-4", "aln": "MEQSQSQRQAWPSSSAGGGKAQDSGVLTREDFDGGPVSIDEVDTGLFLGNLTAATHMETL-RSFKITHILTLDSV-PLPQHILEASFLTTKYIQIADMPREDILQHLEGCVDFIS-----------------SALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMG-CKIDPNCQRYKIHRLRLAGEQMRKAKILP------QSFHSVVRPDPDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQSHDQAENHHGARMLEQLSERIRQSSLGSPGHESTPNYCRSILFVEPIAWMHRIMLN--TQG-RLYCPKCEQKLGNFSWINACKCPCGETMTPAFYLIPSKVELSKAVQNVQTTV----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02256-1", "uniprot_id": "PVH1_YEAST", "id": "Q02256-1", "name": "Tyrosine-protein phosphatase YVH1", "aln": "----------------MAGNANSVD-----------EEVTRILGGIYLGGIRPIIDHRPLGAEFNITHILSVIKF-QVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDFVDFDNPAYKQWKLKQSIKLDPSGSELVSNSGMFKDSESSQDLDKLTEAEKSKVTAVRCKKCRTKLALSTSFIAHDPP-------------------------------SKESSEGHFIKRAANSHRIIDIQESQAN--CSHFFIEPLKWMQPELQGKQELEGKFSCPGCSSKVGGYNWK-GSRCSCGKWVIPAIHLQTSKVDQFPLQSTALPNMVNFESEKVNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:::*. * ** :*:: . : * *:*. :: **. . .: *:.** * *** : : *::* * : * :: : .: * * ** *:. *. :. ** :*: : . : :. : :*::** * : .: * :: :: : *:**: **. : . :: ** *. *:*.:.* . :*.**. : **: : .:*: ", "identical_positions": 53, "similar_positions": 76, "identity": "12.44%" }, { "cls_id": "homologset.agr.SGD:S000001466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62950-1", "uniprot_id": "DPYL1_RAT", "id": "Q62950-1", "name": "Dihydropyrimidinase-related protein 1", "aln": "--MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPG----GVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLV--QDKGVNSFQVYMAYKD------LYQMSDSQLYEAFTFLKG----LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRIN---CPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKD----NFTLIPEGVNGIEERMTVVWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKH--AAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97427-1", "uniprot_id": "DPYL1_MOUSE", "id": "P97427-1", "name": "Dihydropyrimidinase-related protein 1", "aln": "--MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPG----GVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLV--QDKGVNSFQVYMAYKD------LYQMSDSQLYEAFTFLKG----LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRIN---CPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKD----NFTLIPEGVNGIEERMTVVWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKH--AAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14194-1", "uniprot_id": "DPYL1_HUMAN", "id": "Q14194-1", "name": "Dihydropyrimidinase-related protein 1", "aln": "--MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPG----GVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLV--QDKGVNSFQVYMAYKD------VYQMSDSQLYEAFTFLKG----LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRIN---CPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKD----NFTLIPEGVNGIEERMTVVWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKY--ATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62188-1", "uniprot_id": "DPYL3_MOUSE", "id": "Q62188-1", "name": "Dihydropyrimidinase-related protein 3", "aln": "--MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPG----GVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLS--KEKGVNSFMVYMAYKD------LYQVSNTELYEIFTCLGE----LGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTN---CPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKD----NFTAIPEGTNGVEERMSVIWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKG--GTPAGSTRGSPTRPNPP-VRNLHQSGFSLSGTQVDEG-VRSASKRIVAPPGGRSNITSLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62952-1", "uniprot_id": "DPYL3_RAT", "id": "Q62952-1", "name": "Dihydropyrimidinase-related protein 3", "aln": "--MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPG----GVKTIEANGKMVMPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLS--KEKGVNSFMVYMAYKD------LYQVSNTELYEIFTCLGE----LGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTN---CPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKD----NFTAIPEGTNGVEERMSVIWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKG--GTPAGSTRGSPTRPNPP-VRNLHQSGFSLSGTQVDEG-VRSASKRIVAPPGGRSNITSLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14195-1", "uniprot_id": "DPYL3_HUMAN", "id": "Q14195-1", "name": "Dihydropyrimidinase-related protein 3", "aln": "--MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPG----GVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLI--KDKGVNSFMVYMAYKD------LYQVSNTELYEIFTCLGE----LGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTN---CPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKD----NFTAIPEGTNGVEERMSVIWDKAVATG---KMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKG--GTPAGSARGSPTRPNPP-VRNLHQSGFSLSGTQVDEG-VRSASKRIVAPPGGRSNITSLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08553-1", "uniprot_id": "DPYL2_MOUSE", "id": "O08553-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "--MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPG----GVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALV--KDHGVNSFLVYMAFKD------RFQLTDSQIYEVLSVIRD----IGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTN---CPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKD----NFTLIPEGTNGTEERMSVIWDKAVVTG---KMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKT--VTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47942-1", "uniprot_id": "DPYL2_RAT", "id": "P47942-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "--MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPG----GVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALV--KDHGVNSFLVYMAFKD------RFQLTDSQIYEVLSVIRD----IGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTN---CPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKD----NFTLIPEGTNGTEERMSVIWDKAVVTG---KMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKT--VTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16555-1", "uniprot_id": "DPYL2_HUMAN", "id": "Q16555-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "--MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPG----GVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALV--KDHGVNSFLVYMAFKD------RFQLTDCQIYEVLSVIRD----IGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTN---CPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKD----NFTLIPEGTNGTEERMSVIWDKAVVTG---KMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKT--VTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35098-1", "uniprot_id": "DPYL4_MOUSE", "id": "O35098-1", "name": "Dihydropyrimidinase-related protein 4", "aln": "--MSFQGKKSIPRITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPG----GIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALV--RDKGVNSFLVFMAYKD------RCQCTDGQIYEIFSLIRD----LGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQAN---CPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKD----NFTLIPEGVNGIEERMSVVWEKCVASG---KMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVFSAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKP--GSGTQARASCSGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62951-1", "uniprot_id": "DPYL4_RAT", "id": "Q62951-1", "name": "Dihydropyrimidinase-related protein 4", "aln": "----------IPRITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPG----GIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALV--RDKGVNSFLVFMAYKD------RCQCTDGQIYEIFSLIRD----LGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQAN---CPLYITKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKD----NFTLIPEGINGIEERMSVVWEKCVASG---KMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGMPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKP--GSGTQARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14531-1", "uniprot_id": "DPYL4_HUMAN", "id": "O14531-1", "name": "Dihydropyrimidinase-related protein 4", "aln": "--MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPG----GIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADSAACCDYSLHVDITRWHESIKEELEALV--KEKGVNSFLVFMAYKD------RCQCSDSQMYEIFSIIRD----LGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQAN---CPLYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKD----NFALIPEGTNGIEERMSMVWEKCVASG---KMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMVPAKP--GSGAPARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQF5-1", "uniprot_id": "DPYS_MOUSE", "id": "Q9EQF5-1", "name": "Dihydropyrimidinase", "aln": "------------MAPQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLA--RDKGVNSFKMFMAYKG------LYMVQDEQLYAAFSQCKE----IGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN---CPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKD----DFTKIPNGVNGVEDRMSVIWEKGVHSG---KMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPVPVKRAPYKG---EVTTLKAR--ETKEDDTAGTRMQGHS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63150-1", "uniprot_id": "DPYS_RAT", "id": "Q63150-1", "name": "Dihydropyrimidinase", "aln": "------------MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLA--QDKGVNSFKMFMAYKD------LYMVQDQQMYAAFSQCKE----IGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN---CPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKD----DFTKIPNGVNGVEDRMSVIWEKGVHSG---KMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKG---EVITLKPR--ETKEDDTAGTRMQGHS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14117-1", "uniprot_id": "DPYS_HUMAN", "id": "Q14117-1", "name": "Dihydropyrimidinase", "aln": "------------MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILV--QDKGVNSFKMFMAYKD------LYMVTDLELYEAFSRCKE----IGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN---CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKD----DFTKIPNGVNGVEDRMSVIWEKGVHSG---KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKG---EVATLKSR--VTKEDATAGTRKQAHP--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQF6-1", "uniprot_id": "DPYL5_MOUSE", "id": "Q9EQF6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "---------MLANSASVRILIKGGKVVNDDCTHEADVYIESGIIQQVGRELMIPG----GAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLV--REKGVNSFQMFMTYKD------LYMLRDSELYQVFHACRD----IGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTH---CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKE----DFTKIPHGVSGVQDRMSVVWERGVVGG---KMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRGVDRTPYLGDVAIVVHPGKKEMGTPLADTPTRPVTRHGG-MRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHU0-1", "uniprot_id": "DPYL5_RAT", "id": "Q9JHU0-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "---------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPG----GAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLV--REKGVNSFQMFMTYKD------LYMLRDSELYQVFHACRD----FGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTH---CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKE----DFTKIPHGVSGVQDRMSVVWERGVVGG---KMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRGVDRTPYLGDVAVVVNPGKKEMGTPLADTPTRPVTRHGG-MRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPU6-1", "uniprot_id": "DPYL5_HUMAN", "id": "Q9BPU6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "---------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPG----GAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLV--REKGVNSFQMFMTYKD------LYMLRDSELYQVLHACKD----IGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH---CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKE----DFTKIPHGVSGVQDRMSVIWERGVVGG---KMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGG-MRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABT0-1", "uniprot_id": "A0AB13ABT0_DANRE", "id": "A0AB13ABT0-1", "name": "allantoinase", "aln": "MEPGSAVSAVRSQRVLCGEKILPAVIVIK--EGKIHSVLPDS--EASAHVAG---------KVLDVGDSLIMPGIVDSHVHVNEP--GRTDWEGYWTATRAAAAGGITTIADMPLN-----TIPPTTTLRNFNEKLCAATGQCFVDTAFWGGVIPGNQMELKPMCQAGVAGFKCFLIHSG---VEEFPHVTDADLHAAMKQLQG----TNSVLLFHAEQE--LSHPVAE--KGDPQEYSTFLKSRPDIMELEAIHTVIEFCLQY--QVRC-HIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDIP----GRATQFKCCPPIRGTANQELLWSALKAG-DIDMVVSDHSPCTPDLKCLDSG----DFTQAWGGISSLQFVLSLFWTSASKR----GFSFSDAARLLCEEPARLCRLDNQKGSLIPGHDADLVIWDPEKEFTVKEDNIHHKNKLTPYLDRVLRGMVRFTIVRGQVVYSHGSFSSQ-PLGKHLLIQN--KSTTTV---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWW1-1", "uniprot_id": "Q9VWW1_DROME", "id": "Q9VWW1-1", "name": "allantoinase", "aln": "MDLLFLSRRIFLGDGSQNALIHGGIIVDT--EGIIRRVLRSPQ-EVNTYLYNTES-----ESVYDFGDLVLMPGLIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTN-----AQPPTVSVAHLKAKTSTARGKIYVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALSQLDKDQAEGEAIVAVHAELP--LTTEIHPD-EEAPREYGTFLVTRPPQMEISATQLLCRLANRH--PRRCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVP----DCGTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFEGFGQ-PLGKVLLRRSSRKLVKFVSM-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32375-1", "uniprot_id": "ALN_YEAST", "id": "P32375-1", "name": "Allantoinase", "aln": "----MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEI-----HTLENVSPCTILPGLVDSHVHLNEP--GRTSWEGFETGTQAAISGGVTTVVDMPLN-----AIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHNLPDLIPLVKAGVRGFKGFLLDSG---VEEFPPIGKEYIEEALKVLAE----EDTMMMFHAELP--KAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQIP----DGATYFKCCPPIRSESNRQGLWDALREG-VIGSVVSDHSPCTPELKNLQKG----DFFDSWGGIASVGLGLPLMFTQ--------GCSLVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR----------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : . : ::** :* . .: . . :.: .*:** ** * : . . . * : * ** .: : . : : :: .*** :* .* .* :: : * . : .: * : :. . . .: . **: * : : : . .. : : :* * . :.:.: . :.:. : ** : * *:*. ::.. . . . . : . :* .: :* *: ", "identical_positions": 34, "similar_positions": 91, "identity": "5.65%" }, { "cls_id": "homologset.agr.SGD:S000001468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYP0-1", "uniprot_id": "ALLC_RAT", "id": "Q6AYP0-1", "name": "Probable inactive allantoicase", "aln": "---MADTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSNNPSFKENEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQG-IIRGIDVDISYFSGNYAPRMSIQAANLS-EDTVTNIPPRGVKMGAAATSEEFVAITELKSHSWDYLVPMSELKPGDPDSSHNYFFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGDPKSIADGWETARRLDRPPVLEGNENGFLQVPGCEWAVFRLAHPG-VITQIEIDTKYFKGNSPDSCKVDGCILTTLEEEDMIRQKWSLP-AHKWKPLLPVTKLTPNQNHLLDSLTLELQDVITHARITIAPDGGVSRLRLKGFPSSICLLRPLREKPMLRFSLKAGFRANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHX6-1", "uniprot_id": "ALLC_MOUSE", "id": "Q9JHX6-1", "name": "Probable inactive allantoicase", "aln": "---MTDTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSDSPTFKEHEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQG-IIRGIDVDISYFSGNHAPRMSIQAANLSEEDTMSNIPPRGVRMGTAATPEEFEAVTELKSHSWDYLVPMSELKLGDPDSSHNYYFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGEPKSIADGWETARRLDRPPVLEASENGLLLVPGCEWAVFRLAHPG-VITQIEIDTKYFKGNCPNSCKVDGCILTTLEEEDMIRHNWNLP-AHKWKSLLPVTKLIPNQNHLLDSLTLELQDVITHAMITIAPDGGVSRLRLKGFPSSICLLRPLREKPLLRFSLKTGFRANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M5-1", "uniprot_id": "ALLC_HUMAN", "id": "Q8N6M5-1", "name": "Probable inactive allantoicase", "aln": "----------------------MDMASESVGGKILFATDDFFAPAENLIKSDSPCFKEHEYTEFGKWMDGWETRRKRIPGHDWCVLRLGIQG-VIRGFDVDVSYFTGDYAPRVSIQAANLE-EDKLPEIPERGTRTGAAATPEEFEAIAELKSDDWSYLVPMTELKPGNPASGHNYFLVNSQQRWTHIRLNIFPDGGIARLRVFGTGQKDWTATDPKEPADLVAIAFGGVCVGFSNAKFGHPNNIIGVGGAKSMADGWETARRLDRPPILENDENGILLVPGCEWAVFRLAHPG-VITRIEIDTKYFEGNAPDSCKVDGCILTTQEEEAVIRQKWILP-AHKWKPLLPVTKLSPNQSHLFDSLTLELQDVITHARLTIVPDGGVSRLRLRGFPSSICLLRP-REKPMLKFSVS--FKANP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGA6-1", "uniprot_id": "ALLC_DANRE", "id": "Q6DGA6-1", "name": "Allantoicase", "aln": "---MAKRQVQKETRSQPHFLQFNNLACETAGGKVIFATDEWFAPARNLLKRDPPEFIASAFTEFGKWMDGWETRRKRIPGHDWCIVQLGVPG-IIHGFDVDTSFFTGNYAPFASIQATCLD---QMPSIALEGDRTGMAASPSQFEAVAQLNSDSWKEVVPVTKLKAGYSDTCHNYLSVSYPHRVTHIRFNIYPDGGIARLKVYGIGKKDWSSVFGQDLVDLVALVNGGVCVGFSDAHYGHPRNMIGLGMAENMGDGWETARRLDRPRVLKEDENGILQVPGSEWAIFRLGHPG-IISKIELDTNHFKGNFPDSCRIEACSLTEDEENSFIQSQWSSDRSPMWNILLPPQKMKAHHRHVFSGPSLVHCGPVSHVRMVIAPDGGISRLRIWG--------RPVSSHQMISKL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25335-1", "uniprot_id": "ALLC_YEAST", "id": "P25335-1", "name": "Allantoicase", "aln": "MKFFSLADEAEFKSIIISKNKAVDVIGSKLGGQVVSFSDEWFASAENLIQPTAPIRDPTRFVHSGAWYDGWETRRHNEMEYDWVIIKMGVAAAHIIGGEIDTAFFNGNHAPFVSIEALYDE--------GEEGNIVEDDSRWVEIVEKFECGPSQRHLFVRGNGLT---------------KERFTHIKLKMYPDGGIARFRLYGR-VVPPELKTKDHIIDLAYVCNGAVALKYSDQHFGSVDNLLLPGRGHDMSDGWETKRSR--------------QPGHTDWAVIQLGRESSFIEKIIVDTAHFRGNFPQFITVEGCLKESESSENTGEG--------TWVELVGKSKTGPDKEHVY---EIRKSIRVSHVKLTIIPDGGVKRIRVWGY----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . **::: :*::*..*.**:: * :.. * * *******:. :** ::::*: . * * ::* ::*.*::** **:* . .* : :: : . . .* . *. .* ***:::::****:**::::* . **. : *.*.: :*: ::* *:: * ..:.***** * :**:::*.: . .* :* :** :*.** *: ::.* ..: . * *: * ..: *: : ::*. :.* ****:.*:*: * ", "identical_positions": 83, "similar_positions": 107, "identity": "19.76%" }, { "cls_id": "homologset.agr.SGD:S000001474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VNF3-1", "uniprot_id": "Q9VNF3_DROME", "id": "Q9VNF3-1", "name": "Ketoreductase domain-containing protein", "aln": "-----------------------------MPSFKDKVIIVTGASSGIGAGTSVLLAK---LGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESDVQGIVSATLAKHG-----RIDVLVNNAGILE--LGSI-ENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK---GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKE-VAAAIAFLASDEASFSTGISLPVDGGRHAMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPP8-1", "uniprot_id": "Q8IPP8_DROME", "id": "Q8IPP8-1", "name": "Ketoreductase domain-containing protein", "aln": "------------------------------MNFAGKVVLITGASSGIGAATAIKFAK---YGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIAKEADTQRIWSETLQQYG-----KLDVLVNNAGIIE--TGTI-ETTSLEQYDRVMNTNLRAIYHLTMLATPELVKTK---GNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKE-VAAAIAFLASDEASFSTGVSLPVDGGRHAMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNF4-1", "uniprot_id": "Q9VNF4_DROME", "id": "Q9VNF4-1", "name": "Ketoreductase domain-containing protein", "aln": "----------------------MGSKGKAGLDFSGKVVLITGAASGIGAAAAEMFSK---LGACLALVDREEEGLICVMKRCMKMG-HEPYGIAGDLLKPPEIECIARKTTERYEG----KLDVLVNGAGIMP--TGTL-QSTELACFTHVMEANVRSGFYLTKLLLPQLLQCK---GSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKE-VAAAICFLASELASFVTGVTLPVDGGKQVMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U1L2-1", "uniprot_id": "Q9U1L2_DROME", "id": "Q9U1L2-1", "name": "Ketoreductase domain-containing protein", "aln": "------------------------------MSLSNKVVIVTGASSGIGAAIAQVLAR---EGATLALVGRNVANLEATKK---SLKGTQAEIVVADVTK--DADAIVQQTLAKFG-----RIDVLVNNAGILG--KGGL-IDLDIEEFDAVLNTNLRGVILLTKAVLPHLLKTK---GAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIHRNIGIVDEEYNGMLQRAINSHPMGRVGDVTE-VAEAVAFLASSKASFTTGALFPIDGGKHNLTPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9Q3D4-1", "uniprot_id": "DHB14_MOUSE", "id": "E9Q3D4-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------MAAVTRYSGKVVVVTGGSRGIGAAIVRAFVD---SGAQVVFCDKD-----EAGGRALEQELSGTVFIPGDVTQERDLQTLVSETLSRFG-----HLDCVVNNAGYHP--PAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPHLRKSR---GNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEELAASTSDPRATILEGTLAQPLGRMGQPAE-VAAAAVFLAS-EATFCTGLELLVTGGAELGYGRKASKSSLGEVPTLPPNVH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VWP2-1", "uniprot_id": "Q9VWP2_DROME", "id": "Q9VWP2-1", "name": "Ketoreductase domain-containing protein", "aln": "----------------------------MWTDLAGKVILVTGAGAGIGQALVKQLAS---AGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSG--------WQAVREGLAKVP-----LLDGLVNNAGVAI--IKPF-EELTEQDFDTHFDVNIKAVFNVTQSLLPRLKDG----ASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADNWSDPAKSGPLLAH----IPLNRFCEVQE-VVDATGYLLSSKSSFVNGHHILLEGGYSVS--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7Z5J1-1", "uniprot_id": "DHI1L_HUMAN", "id": "Q7Z5J1-1", "name": "Hydroxysteroid 11-beta-dehydrogenase 1-like protein", "aln": "---MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYAR---LGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGG----LDYLVLNHIGGAP--AGTR--ARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK---GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFL-PPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28845-1", "uniprot_id": "DHI1_HUMAN", "id": "P28845-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "MAFMKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAK---MGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGG----LDMLILNHITNTS--LNLF--HDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSN---GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKE-----ECALEIIK-GGALRQEEVYYDSSL--WTTLLIRNPCRK--------ILEFLYSTSYNMDRFINK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18297-1", "uniprot_id": "SPRE_RAT", "id": "P18297-1", "name": "Sepiapterin reductase", "aln": "---------------------------MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVE--EPSVRVLSYAPGPLDTNMQQLARETSMDP-ELRSRLQKLNSEGELVDCG--TSAQKLLSLLQRDTFQSGAHVDFYDI------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZT59-1", "uniprot_id": "D3ZT59_RAT", "id": "D3ZT59-1", "name": "Sepiapterin reductase", "aln": "---------------------------MEGGGLGCTECLLTRVSQGFPRSAAAAPG----P-AVLLLSAHSDSVLQQLNGELGAQQPGLQVMLAATDLGTKA--IQLLSAVRELARPKRLS-LLLINSAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVE--EPSVRVLSYAPGPLDTNMQQLARETSMDP-ELRSRLQKLNSEGELVDCG--TSAQKLLSLLQRDTFQSGAHVDFYDI------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35270-1", "uniprot_id": "SPRE_HUMAN", "id": "P35270-1", "name": "Sepiapterin reductase", "aln": "---------------------------MEGG-LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDP-DMRKGLQELKAKGKLVDCK--VSAQKLLSLLEKDEFKSGAHVDFYDK------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40579-1", "uniprot_id": "NRE1_YEAST", "id": "P40579-1", "name": "Benzil reductase ((S)-benzoin forming) NRE1", "aln": "---------------------------------MGKVILVTGVSRGIGKSIVDVLFS-LDKDTVVYGVARSEAPLKKLKEKY----GDRFFYVVGDITEDSVLKQLVNAAVKGHG-----KIDSLVANAGVLEPVQNVN--EIDVNAWKKLYDINFFSIVSLVGIALPELKKTN---GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKLALHGIPDGVNGQYLSYNDPALADFMP--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* *. : : :: *. . : : . :: :** * * . : : : :.. : . ", "identical_positions": 7, "similar_positions": 24, "identity": "2.08%" }, { "cls_id": "homologset.agr.SGD:S000001475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZV9-1", "uniprot_id": "DHRS6_MOUSE", "id": "Q8JZV9-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "-----------------------------MGRLDGKVIVLTAAAQGIGRASALAFA---REGAKVIATDINESKLQELESYR-GIQT-RVLDVTKKR-----QIDQFASEIER--------IDVLFNVAGFVHHGTILDCEEKD-----WDFSMNLNVRSMFLMIKAFLPKMLAQKS--GNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDN---PKEALKTFLNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q3D4-1", "uniprot_id": "DHB14_MOUSE", "id": "E9Q3D4-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------MAAVTRYSGKVVVVTGGSRGIGAAIVRAFV---DSGAQVVFCDKDEAGGRALEQELSGTVF-IPGDVTQER-----DLQTLVSETLSRFG----HLDCVVNNAGYHPPAQLPEETSAQG----FRQLLEVNLLGTYTLIKLALPHLRKSR---GNIINISSLVGAIGQSQ-ALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEELAASTSD---PRATILEGTLAQPLGRMGQPAEVAAAAVFLAS-EATFCTGLELLVTGGAELGYGRKASKSSLGEVPTLPPNVH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VNF3-1", "uniprot_id": "Q9VNF3_DROME", "id": "Q9VNF3-1", "name": "Ketoreductase domain-containing protein", "aln": "-----------------------------MPSFKDKVIIVTGASSGIGAGTSVLLA---KLGGLLTIVGRNLDKLNETAEQIVAAGG-APALQVAADINSESDVQGIVSATLAKHG----RIDVLVNNAGILELGSIENTSLEQ-----FDRVMNTNVRSLYQLTHLVTPELIKTK---GNIVNVSSVNG-IRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLDQEA---YVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGRHAMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPP8-1", "uniprot_id": "Q8IPP8_DROME", "id": "Q8IPP8-1", "name": "Ketoreductase domain-containing protein", "aln": "------------------------------MNFAGKVVLITGASSGIGAATAIKFA---KYGACLALNGRNVENLKKVAAECSKVSQ-SQPALVVGDIAKEADTQRIWSETLQQYG----KLDVLVNNAGIIETGTIETTSLEQ-----YDRVMNTNLRAIYHLTMLATPELVKTK---GNIVNVSSVNG-IRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHARGGMDAET---YKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGGRHAMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNF4-1", "uniprot_id": "Q9VNF4_DROME", "id": "Q9VNF4-1", "name": "Ketoreductase domain-containing protein", "aln": "----------------------MGSKGKAGLDFSGKVVLITGAASGIGAAAAEMFS---KLGACLALVDREEEGLICVMKRCMKMG--HEPYGIAGDLLKPPEIECIARKTTERYEG---KLDVLVNGAGIMPTGTLQSTELAC-----FTHVMEANVRSGFYLTKLLLPQLLQCK---GSIVNVSSVCG-LRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNLQKAGGMDEQS---YAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGGKQVMCPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U1L2-1", "uniprot_id": "Q9U1L2_DROME", "id": "Q9U1L2-1", "name": "Ketoreductase domain-containing protein", "aln": "------------------------------MSLSNKVVIVTGASSGIGAAIAQVLA---REGATLALVGRNVANLEATKK---SLKG-TQAEIVVADVTK--DADAIVQQTLAKFG----RIDVLVNNAGILGKGGLIDLDIEE-----FDAVLNTNLRGVILLTKAVLPHLLKTK---GAVVNVSSCAG-IRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIHRNIGIVDEE---YNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTGALFPIDGGKHNLTPR-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWP2-1", "uniprot_id": "Q9VWP2_DROME", "id": "Q9VWP2-1", "name": "Ketoreductase domain-containing protein", "aln": "----------------------------MWTDLAGKVILVTGAGAGIGQALVKQLA---SAGATVIAVARKPEQLQQLVAFDPVHIQ-PLQLDLSG--------WQAVREGLAKVP----LLDGLVNNAGVAIIKPFEELTEQD-----FDTHFDVNIKAVFNVTQSLLPRLKDG----ASIVNVSSIAS-SRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADNWSDPAK---SGPLLAHIP----LNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGGYSVS--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7Z5J1-1", "uniprot_id": "DHI1L_HUMAN", "id": "Q7Z5J1-1", "name": "Hydroxysteroid 11-beta-dehydrogenase 1-like protein", "aln": "---MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYA---RLGSHLVLTAHTEALLQKVVGNCRKLGA-PKVFYIAADMASPEAPESVVQFALDKLGG---LDYLVLNHIGGAPAGTRARSPQAT------RWLMQVNFVSYVQLTSRALPSLTDSK---GSLVVVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSS---TSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28845-1", "uniprot_id": "DHI1_HUMAN", "id": "P28845-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "MAFMKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLA---KMGAHVVVTARSKETLQKVVSHCLELGA-ASAHYIAGTMEDMTFAEQFVAQAGKLMGG---LDMLILNHITNTSLNLFHDDIHHV------RKSMEVNFLSYVVLTVAALPMLKQSN---GSIVVVSSLAG-KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGI---VHMQAAPKE-----ECALEIIKGGALRQEEVYYDSSL--WTTLLIRNPCRK--------ILEFLYSTSYNMDRFINK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40580-1", "uniprot_id": "BZRD_YEAST", "id": "P40580-1", "name": "Benzil reductase ((S)-benzoin forming) IRC24", "aln": "---------------------------------MGKVILITGASRGIGLQLVKTVI---EEDDECIVYG-VARTEAGLQSLQREYGA-DKFVYRVLDITDRSRMEALVEEIRQKHG----KLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSIVSLVALCLPLLKSSPFV-GNIVFVSSGAS-VKPYNGWSAYGCSKAALNHFAMDIASEEPSDKVRAVCIAPGVVDTQMQKDIRETLGPQGMTPKALERFTQLYKTSSLLDPKVPAAVLAQLVLKGIPDSLNGQYLRYNDERLGPVQG----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18297-1", "uniprot_id": "SPRE_RAT", "id": "P18297-1", "name": "Sepiapterin reductase", "aln": "---------------------------MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNIND--LAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCA-LQPFKGWGLYCAGKAARDMLYQVLAVEEPS--VRVLSYAPGPLDTNMQQLARETSMD----PELRSRLQKLNSEGELVDCG-TSAQKLLSLLQRDTFQSGAHVDFYDI------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.. *.* . :. *. . : : :: :** . * * . : : : :. . . ", "identical_positions": 8, "similar_positions": 24, "identity": "2.35%" }, { "cls_id": "homologset.agr.SGD:S000001476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70325-1", "uniprot_id": "GPX4_MOUSE", "id": "O70325-1", "name": "Phospholipid hydroperoxide glutathione peroxidase GPX4", "aln": "--------MSWGRLSRLLKPALLCGALA-APG------------------LAGTMCASR----------------------DDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSN-QEIKEFAA-GYNVKF-DMYSKICVNGDDAHPLWKWMKVQPKGRGMLGN-AIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36970-1", "uniprot_id": "GPX4_RAT", "id": "P36970-1", "name": "Phospholipid hydroperoxide glutathione peroxidase", "aln": "--------MSWGRLSRLLKPALLCGALA-VPG------------------LAGTMCASR----------------------DDWRCARSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSN-QEIKEFAA-GYNVRF-DMYSKICVNGDDAHPLWKWMKVQPKGRGMLGN-AIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36969-1", "uniprot_id": "GPX4_HUMAN", "id": "P36969-1", "name": "Phospholipid hydroperoxide glutathione peroxidase GPX4", "aln": "--------MSLGRLCRLLKPALLCGALA-APG------------------LAGTMCASR----------------------DDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSN-EEIKEFAA-GYNVKF-DMFSKICVNGDDAHPLWKWMKIQPKGKGILGN-AIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAF3-1", "uniprot_id": "A0A8M1PAF3_DANRE", "id": "A0A8M1PAF3-1", "name": "Glutathione peroxidase", "aln": "-----------MQKMGFIHRFLLFGALS-SSG------------------IIGATSAQL----------------------EDWQTAKSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRILAFPSNQFGRQEPGTN-SQIKEFAK-SYNAEF-DMFSKIDVNGDGAHPLWKWLKDQPNGKGFLGN-GIKWNFTKFLINREGQVVKRYSPLQDPSVVEKDLSKYL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N743-1", "uniprot_id": "A0A8M1N743_DANRE", "id": "A0A8M1N743-1", "name": "Glutathione peroxidase", "aln": "--------------MWLFQRALLVGAVG-SKS------------------FARAMCAQA----------------------NDWQSAKSIYEFSAIDIDGNDVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHVTYAEKGLRILGFPCNQFGKQEPGSE-AEIKEFAK-GYNAEF-DLFSKIDVNGDAAHPLWKWMKEQPKGRGTLGN-NIKWNFTKFLIDREGQVVKRYGPMDDPSVVEKDLPKYL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRD3-1", "uniprot_id": "Q8IRD3_DROME", "id": "Q8IRD3-1", "name": "Glutathione peroxidase", "aln": "--------MSLRQFQNISRQALRCYSMRRTPGPVLELSRGQRQCLRLCTIMLPVSCAATPMNAISSAAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLR-DSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTG--TLGS-GIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40581-1", "uniprot_id": "GPX3_YEAST", "id": "P40581-1", "name": "Glutathione peroxidase-like peroxiredoxin HYR1", "aln": "--------------------------------------------------------------------------------------MSEFYKLAPVDKKGQPFPFDQLKGKVVLIVNVASKCGFTP-QYKELEALYKRYKDEGFTIIGFPCNQFGHQEPGSD-EEIAQFCQLNYGVTF-PIMKKIDVNGGNEDPVYKFLKSQKSG--MLGLRGIKWNFEKFLVDKKGKVYERYSSLTKPSSLSETIEELLKEVE-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9D7B7-1", "uniprot_id": "GPX8_MOUSE", "id": "Q9D7B7-1", "name": "Protein peroxidase GPX8", "aln": "MEPFAAYPLKCSGPKAKIFAVLLSMVLCTVML-----------------FLLQLKFLKP--------------------------RTNSFYSFEVKDAKGRTVSLEKFKGKASLVVNVASDCRFTDKSYQTLRELHKEFGPYHFNVLAFPCNQFGESEPKSS-KEVESFARQNYGVTF-PIFHKIKILGPEAEPAFRFIVDSSKK-------EPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99LJ6-1", "uniprot_id": "GPX7_MOUSE", "id": "Q99LJ6-1", "name": "Protein peroxidase GPX7", "aln": "----------------------MVAAVATAWL-----------------LLWAAACAQS--------------------------EQD-FYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQNYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDTN-REIENFARRTYSVSF-PMFSKIAVTGTGAHPAFKYLTQTSGK-------EPTWNFWKYLVDPDGKVVGAWDPTVPVAEIKPRITEQVMKLILRKREDL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: : *. . ::: :* . ::.*:**. * .* : : : :: **.**** . * :. : . . : : *: : * * :::: *** *:*:: .* : . : : . ", "identical_positions": 23, "similar_positions": 47, "identity": "8.81%" }, { "cls_id": "homologset.agr.SGD:S000001484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FL77-1", "uniprot_id": "F7FL77_RAT", "id": "F7FL77-1", "name": "", "aln": "-------------------MSEIKKQ---------KTDQQ-----KSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSNYEKPETPECVLKTNLSSVSDCVQQVVELLQEQSIVP--HTTIKGIHELFVPE-NKIDQIRAELETLPSLPITKLDLQWVQILSEGWATPLKGFMREKEYLQTLHFDTLLDGVILRDGVINMSIPIVLPVSGDDKARLEGCSKFALMYEGRRVALLQDPEFYEHRKEERCSRVWGTASAKHPHIKMVMEGGDWLVGGDLQVLERIRWNDGLDQYRLTPLELKQKCKDMDADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGILDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFYIVGRDPAGMPHPETK----KDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHDEFDFISGTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88428-1", "uniprot_id": "PAPS2_MOUSE", "id": "O88428-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "aln": "-------------------MSANFKMNH-------KRDQQ-----KSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVARLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPECVLKTNLSSVSDCVQQVVELLQEQNIVP--HTTIKGIHELFVPE-NKVDQIRAEAETLPSLPITKLDLQWVQILSEGWATPLKGFMREKEYLQTLHFDTLLDGVVPRDGVINMSIPIVLPVSADDKARLEGCSKFALMYEGRRVALLQDPEFYEHRKEERCSRVWGTATAKHPHIKMVMESGDWLVGGDLQVLERIRWDDGLDQYRLTPLELKQKCKDMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLEWRMKQHAAVLEERVLDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFYIVGRDPAGMPHPETK----KDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHEEFDFISGTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95340-1", "uniprot_id": "PAPS2_HUMAN", "id": "O95340-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "aln": "-------------------MSGIKKQK--------TENQQ-----KSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVP--YTIIKDIHELFVPE-NKLDHVRAEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLD-----DGVINMSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKHPHIKMVMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETK----KDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60967-1", "uniprot_id": "PAPS1_MOUSE", "id": "Q60967-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "---------------MEIPGSLCKKVKL-------SNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP--VDASYEVKELYVPE-NKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDG-----GVINLSVPIVLTATHEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVLEQGDWLIGGDLQVLDRIYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILDPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K0L0-1", "uniprot_id": "A0A0G2K0L0_RAT", "id": "A0A0G2K0L0-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "---------------MEIPGSLCKKVKL-------SNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP--VDASYEVKELYVPE-NKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDG-----GVINLSVPIVLTATQEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCRSHPYIKMILEQGDWLIGGDLQVLDRIYWNDGLDQYRLTPAELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSDHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43252-1", "uniprot_id": "PAPS1_HUMAN", "id": "O43252-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "---------------MEIPGSLCKKVKL-------SNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP--VDASYEVKELYVPE-NKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDG-----GVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQV1-1", "uniprot_id": "Q8IQV1_DROME", "id": "Q8IQV1-1", "name": "", "aln": "MFTRCANSLGLYHNNINNNNSACCAASPKRSCLPSVEKPEDACLQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSG-MDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATYYQNLPQS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02196-1", "uniprot_id": "KAPS_YEAST", "id": "Q02196-1", "name": "Adenylyl-sulfate kinase", "aln": "---------------------------------------------MATNITWHPN-LTYDER-KALRKQD---GCTIWLTGLSASGKSTIACALEQLLLQKNLSAYRLDGDNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITSFISPYRVDRDRARELHKEAGLKFIEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPKAPELHLRTDQKTVEECATIIYEYLISEKIIR---------KHL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:. : : :: : * : : ***:******.:**:::: ** *: : :..* *****:* ***::***: **:**:**:.**::****: :.* **:**: **: **::*: *.* * *:***.**.:.* ** *****:** * ** **** ** *: ** :.*. * :.. : * .. *: .* ", "identical_positions": 88, "similar_positions": 60, "identity": "13.35%" }, { "cls_id": "homologset.agr.SGD:S000001485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43633-1", "uniprot_id": "CHM2A_HUMAN", "id": "O43633-1", "name": "Charged multivesicular body protein 2a", "aln": "----MDLLFGRRKTPEELLRQNQR------------ALNRAMRELDRERQKLETQEKK-----IIADIKKMAKQGQMDAVRIMAKDLVRTR----------RYVRKFVLMRANIQAVSLKIQTLKSNNS-----------------------MAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFE-RQAEIMDMKEEMMNDAIDDAMGDEEDE-EESDAVVSQVLDELGLSLTDELS-----NLPSTGGSLSVAAGG---------------------KKAEAAASALADADADLEERLKNLRRD-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB34-1", "uniprot_id": "CHM2A_MOUSE", "id": "Q9DB34-1", "name": "Charged multivesicular body protein 2a", "aln": "----MDLLFGRRKTPEELLRQNQR------------ALNRAMRELDRERQKLETQEKK-----IIADIKKMAKQGQMDAVRIMAKDLVRTR----------RYVRKFVLMRANIQAVSLKIQTLKSNNS-----------------------MAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFE-RQAEIMDMKEEMMNDAIDDAMGDEEDE-EESDAVVSQVLDELGLSLTDELS-----NLPSTGGSLSVAAGG---------------------KKAEATASALADADADLEERLKNLRRD-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZW25-1", "uniprot_id": "CHM2A_DANRE", "id": "Q7ZW25-1", "name": "Charged multivesicular body protein 2a", "aln": "----MESLFGRRKTPEEMLRQNQR------------ALNRAMRDLDRERQRLEQQEKK-----IIADIKKMAKQGQMDAVKIMAKDLVRTR----------RYVKKFIMMRANIQAVSLKIQTLKSNNS-----------------------MAQAMKGVTKAMATMNRQLKLPQIQKIMMEFE-RQSEIMDMKEEMMNDAIDDAMGDEDDE-EESDAVVSQVLDELGLTLSDELS-----NLPATGGSLSVAAG----------------------KKAEPQP-TLADADADLEERLNNLRRD-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36108-1", "uniprot_id": "DID4_YEAST", "id": "P36108-1", "name": "DOA4-independent degradation protein 4", "aln": "-MSLFEWVFGKNVTPQERLKKNQR------------ALERTQRELEREKRKLELQDKK-----LVSEIKKSAKNGQVAAAKVQAKDLVRTR----------NYIQKFDNMKAQLQAISLRIQAVRSSDQ-----------------------MTRSMSEATGLLAGMNRTMNLPQLQRISMEFE-KQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQST-PQNLVSNAPIAETAMGIP--------------------EPIGAGSEFHGNPDDDLQARLNTLKKQT----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I5ZYZ8-1", "uniprot_id": "A0A8I5ZYZ8_RAT", "id": "A0A8I5ZYZ8-1", "name": "NEDD8-conjugating enzyme UBC12", "aln": "SPPQTEIPELNRRKPNLKLQRGASRGVGWGRCKSCAGAERSRARKNRSGQTTESAEAAGCPRPLPTSASKPRLPRKLSLHRYPAVPCRRKRGCRLLLPPHRSLLAKGASRRESGGPVKAGVRSRSGDSQDPSGRGGGGRGGRSRGGAEDSRVLPSTSEHTRGAKPGQSRTTGAEAGRAVGAEQRGRMIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. .*: *::. . :*: :*. : * : : :. .* :: : * *.* : * : . .:. ::: .... :. : . . .* : : * . : .::. ::: :: . .. .: . :: :.: ::*:.: . ::. :* * : : * : : *: *:.: ", "identical_positions": 18, "similar_positions": 84, "identity": "4.88%" }, { "cls_id": "homologset.agr.SGD:S000001486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6D0-1", "uniprot_id": "F1M6D0_RAT", "id": "F1M6D0-1", "name": "Small ribosomal subunit protein bS6m", "aln": "MPRYELALILKAMR----RPETAAALKRTIESLMDRGAIVRNLENLGERALPYRISSHSQQHSRGGWWPSEFHLVVYRCIKLYTHNGHIESTFLHWAAEASPQGGDLLPRYFLVDFYAPTNAVESMLEHLARDTDVVRPNIVKH--PLTQEVKECDGIVP----VPLEEKLYSTKRRKK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58064-1", "uniprot_id": "RT06_MOUSE", "id": "P58064-1", "name": "Small ribosomal subunit protein bS6m", "aln": "MPRYELALILKAMR----RPETAAALKRTIESLMDRGAIVRNLESLGERALPYRISSHSQQHSRGG--------------------------------------------YFLVDFYAPTSAVENILEHLARDIDVVRPNIVKH--PLTQEVKECDGIVP----VPLEEKLYSTKRRKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82932-1", "uniprot_id": "RT06_HUMAN", "id": "P82932-1", "name": "Small ribosomal subunit protein bS6m", "aln": "MPRYELALILKAMQ----RPETAATLKRTIEALMDRGAIVRDLENLGERALPYRISAHSQQHNRGG--------------------------------------------YFLVDFYAPTAAVESMVEHLSRDIDVIRGNIVKH--PLTQELKECEGIVP----VPLAEKLYSTKKRKK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZD5-1", "uniprot_id": "RT06_DROME", "id": "Q9VZD5-1", "name": "Small ribosomal subunit protein bS6m", "aln": "MPSYELALVLRQLP----RPELISVIRRTAESILDKGGIIRKLENLGSRALPHKVSEHGVVHREGT--------------------------------------------HFTIAFDTAPTKIADLKEEFGRDIDIIRRYIFKVEEPEQKPCTLHEEMLPPAYRKDVQEIIAAAQKKQKKKFNYNSGLDYYPFQK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28778-1", "uniprot_id": "RT06_YEAST", "id": "P28778-1", "name": "Small ribosomal subunit protein bS6m", "aln": "-MLYELIGLVRITNSNAPKLEAKELSSTIGKLIIQNRGVVRDIVPMGIRYLPKIMKKDQEKHFRAY--------------------------------------------HFLMLFDSSAAVQSEILRTLKKDPRVIRSSIVKV--DLDKQLDRASSLHRSLGKKSILELVNEDYQSI-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ::: : * : :::. .::*.: :* * ** :. . * .. :* : * :.. .: . : :* ::* *.* : . : : * : : ", "identical_positions": 17, "similar_positions": 39, "identity": "8.72%" }, { "cls_id": "homologset.agr.SGD:S000001488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58H2V9-1", "uniprot_id": "A0AC58H2V9_DANRE", "id": "A0AC58H2V9-1", "name": "", "aln": "MNFSLQYFYWRFFNRLLILTGACICCKWNRIKLKKSLWKFISMGRNISCALRLVNLANHTVQVFMDIVGGSFNHLVPSDQLDDSLLLGQNLECEASDEFEAKPEDSLKNMLSDKDPMFGSASTQFHLLENEDFKLGSSADADHEMTGAGVRQSPSDGEHNQSGFLQDRRQAGQMQRRQTASRGRVRGRRLGPARKAAESYNRESTCSEEHDRDNSPDEKREALLSRRFGVHEVDSSMNPVVVLRRLTVTVGGYKIELLPGPSQSFGSFSTSALQSLGFQDDGIIADGLGLDLGQNQDEQVVDNSTPEAVGEVSIDQSTSHDVPMDFGPYVNPNEVQDTNSTMVLKPKVENATSEDAKKKNNQIKTQKLSAQKPGNKNGTAARPAVKKLLKNKQSLSAAKNKPSSPTKPGLLQKESKHPQDKKIHTGQPEVHKGKPIKVGLKRPGAALGPKDGSKIQKIQDGHSASKTASPSGPLSPTITKKSSSESGPLSPTNSRKPSSDSVPLSPTNSRKPSNSVPLSSTNSRKPSSNSVPLSPSNSRKPSSNLVPLSPTNSRKLSSDSGPLSPTNSRKPSSDSVPLSPTNSRRPSSESGPGVKSVQSPHPPKKPQNPPTSGNKTNPPVANSQGDEEQDKVKAKKIEKTQQRHKSRNSRSISIEEPQLFIPDNAPVVKKEAEGDALAESETVWDPTKNCVLCKKPHNNRFMVGCGRCDDWFHGDCVGLDLAKVQQMEKEDQEYVCLKCCAQEDEKTQASELSDDKSAAKQKQRPQQSLTAGGIRPFRKDAGERRPSEDSAQKGPNVKHETKKVKISPVSSKKPSTGHIRRSVRDSLEEILLKRSKESDLKISSDRPAEVARRTEKELFALFQGVDSKYKNKYRSLTFNLKDAKNNVLFKRVLKGEVSPADLVRMTAEELASKELAAWRKRENRHTIEMIEKEQREVERRPITKITHKGEIEIENQEPAKAPEAIEVEPEPVLKVVEVPEEKPPEIKVESPKKSIDTTNLHKSHLFDLNCKICTGRMAPPTEEASTKVVKVATTVVRRQSSATEESQPSTTTPTSALMDDLTLRAMEEGLLNFLPESSRADSLCSKEDTATFLSSLESLWGGYVDMPAVARFLTKSYLVSGTLDHLTQDLPDNIQVGGRISPQIVWDYVEKIRASGTKEICVIRFSPDTEEDEISYTLLYAYFSSRRRYGVVANNRKQVKDMYLIPLGSTEKIPHQIVPFDGPGLETNRPNLLLGLIIRQRPKRDFGVILPSDVSEAPSFLAESKPQVDYPQKTPVALDTEQSFISDLGNARKKDTTDLIKSVVEEPILDTETDENVSLRFLPGVLKLPEKAASCSNDNMKSDSTKTEAKTPSVDSGNNATVSPKPIASAPRLDRFVIKKKEPKAVKTEQAPVSVSLEISSEKKETAVVLSLSDKPADVSTESFLSSLTNTKPKEESESCSTASPTSQETSQTTSSGTSKDSVDEGSSSAPKNETISSPTATTKVSPAGILKRASSAPEPTESKLPESSSEKPEQKVTPQPSTQECKAIEDIQAITTISSIGKNEGLKQSRSSSFNPKVYNPPVFHSYLSGPPDPQFYPPPANPAHFLPLQAHLPPPFQFPPGPPPLQMFPQSDPHMLAPPWPQTVPPQTLPPPPMAYESSLPTALPLSKDEKVSEKSYSDFVDKLSRRSEETHRKDSRDREHYDKHHHKSRHYERDREKHRERSHSHKERHSKDERYEKHRERRHSSHHRDRDKHRSRDSDHEKHRKDSRDRRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36106-1", "uniprot_id": "BYE1_YEAST", "id": "P36106-1", "name": "Transcription factor BYE1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MSVRTSSRSNKGQNKYIEYLLQEETEAPKKKR---------------------TKKKVDSAIEKNKKSDSSQEPR-----------------------------------------------------------------------------------KDTENVRTDEVDEADEGYVRCLCG------------------------------ANNENYDAAEYSHGDMVQCDGCDTWQHIKCMTDGKD------------TIDGLMSEDSKY----------------------------------------YCELCDPSLYAHLETSKEAEVSEDEDYHDDVYKPVNDHDDNDADVFLDEESPRK----------------------------------------------------------------------RKRSPDSAKGIHIKSKQVKKS--------NGSKKRNKSIDAAKSDTAENEMPTRKDFESEKEHKLRYN------------------------------------------------------------------------------AEKMFSTLFSKFIVPETIEAKLYELPDGKDVIS----------------------------------------------------------ISQEFAHNLEEELYKACLN----------------------VEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNKLVNMNASELANPDLQEFKEKRDK---IILENFIVEVPDKPMYVKTHKGDELIED-------------------------IAEPQEDILYSKDSIRLHNIDS--------------------------IDSDKSKIEQTHAISKEPSPSTIINEESLN------------------------------CAFLYPGLGLEFTGYLNYIGASQKLRRDIFKEAIGD-------GKLYVEGRLPTTTAAPYLKEISCS-RAILVYQLFPSNDSESKTTFADVVDSLENKGRIAGIKPKTRYEKDFYIVPS-KGGEIPEILKDILGSHNDER--------------------------------------------------------SERFSRMKSDERTLFAFVVVKQEFIH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . ...*::: :* :.. . ::* : :: .:. *::.:.:*.:* * . .* * .:*:: . * * :*:: .: : * . : :* : :* : ..*: * **:.::**: : ..* * . . .. :::... ... .*.*.:. .. .* *. ..** ..* *.* .* :** * :. ...:* * .: ::.* :::: ::* ::::.** * . :: . : * . * ::: **.*.*.. . * :.. ..*** * * . : . * :*. *.:* *** **** ** * :*::*::. .**.*.*.***. :* ::::.:: ::*: ** :*: ****: **: *: .: .*.** *:.. :. .: :.: : ::*..*** .:* * : ..* : **:: ..:: * :. : .. * .:: * **:.. . *:::* .* : *..: .*.: ::: : :..: * . : : : **:*::* . :**. : : *. : . . :.. :..: * : **:: ::. ", "identical_positions": 125, "similar_positions": 256, "identity": "7.12%" }, { "cls_id": "homologset.agr.SGD:S000001489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR57-1", "uniprot_id": "RL14_MOUSE", "id": "Q9CR57-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKAPAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63507-1", "uniprot_id": "RL14_RAT", "id": "Q63507-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAA---KAKVPAKKATGPGQKAAAQKASAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZHE6-1", "uniprot_id": "D3ZHE6_RAT", "id": "D3ZHE6-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYISFGSHAGKLVSFVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFRLRFTCSACQKYVRKAWEKADINTKSAATRWAKIIDARERKAKMTDFDRFKVIKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAT---KAKVPAKKATGPG-----QKAPAQKAAG-KAAPPAKGQKGQKTPAQKAPAPKATGKKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50914-1", "uniprot_id": "RL14_HUMAN", "id": "P50914-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAA--AAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36105-1", "uniprot_id": "RL14A_YEAST", "id": "P36105-1", "name": "Large ribosomal subunit protein eL14A", "aln": "MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVK---KALAKA------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P55841-1", "uniprot_id": "RL14_DROME", "id": "P55841-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MPFERFVQTGRIAKASAGPLKGRLVAIVDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTKYRIKFPYTAPTRIVRKAWTESDLKAQWKVSPWSVKAQNICKRSSLNDFDRFKLRYAKRQRNKLLTIAFNTLKKRTKADGTPR----------------------------------------VLKKDRRERLRAEKAKGGKKAAAKK-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:.**:. . * *:*.::*::***::.*:*** : * ** : : ** : :. * * : * : : : .: *: ::: :.**:**:: :: :. :. : * : ", "identical_positions": 29, "similar_positions": 44, "identity": "12.89%" }, { "cls_id": "homologset.agr.SGD:S000001490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUV6-1", "uniprot_id": "CAZA3_RAT", "id": "Q9WUV6-1", "name": "F-actin-capping protein subunit alpha-3", "aln": "MS--LSVLSRQDKEKVIHRLLIQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYCVPLCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGIIRNENE-YLRSVVMCALKLYVNDHYPNGNCNVLRKTVKNKEFLIACIEKHSYDNGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHYFRCVNLHVEVSKDLKESLEVVNQAQLALSFARLVEEQENKFQAAVIEELQELSNEALRKILRRDLPVTRTLIDWQRILSDLNLVMYPKLGYVIYSRSVLCNWII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70190-1", "uniprot_id": "CAZA3_MOUSE", "id": "P70190-1", "name": "F-actin-capping protein subunit alpha-3", "aln": "MS--LSVLSRKEKEKVIHRLLVQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYCVPLCIDG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGIIRNETE-YLRSVVMCALKLYVNDHYPNGNCNVLRKTVKSKEFLIACIEDHSYDNGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEVSKDLKESLEVVNQAQLALSFARLVEEQENKFQAAVIEELQELSNEALRKILRRDLPVTRTLIDWQRILSDLNLVMYPKLGYVIYSRSVLCNWII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KX2-1", "uniprot_id": "CAZA3_HUMAN", "id": "Q96KX2-1", "name": "F-actin-capping protein subunit alpha-3", "aln": "MT--LSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDG--NPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAE-YLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47754-1", "uniprot_id": "CAZA2_MOUSE", "id": "P47754-1", "name": "F-actin-capping protein subunit alpha-2", "aln": "MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPY-EAENAIE-SWRTSVETALRAYVKEHYPNGVCTVYGKKVDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTVTPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1K5-1", "uniprot_id": "CAZA2_RAT", "id": "Q3T1K5-1", "name": "F-actin-capping protein subunit alpha-2", "aln": "MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPY-EAENAIE-SWRTSVETALRAYVKEHYPNGVCTVYGKKVDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTVTPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47755-1", "uniprot_id": "CAZA2_HUMAN", "id": "P47755-1", "name": "F-actin-capping protein subunit alpha-2", "aln": "MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPC-EVENAVE-SWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47753-1", "uniprot_id": "CAZA1_MOUSE", "id": "P47753-1", "name": "F-actin-capping protein subunit alpha-1", "aln": "MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPE-DVDGGLK-SWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPSAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEVQTTKEFIKIIESAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GUZ5-1", "uniprot_id": "CAZA1_RAT", "id": "B2GUZ5-1", "name": "F-actin-capping protein subunit alpha-1", "aln": "MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPE-DVDGGLK-SWRDSCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEVQTAKEFIKIIESAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52907-1", "uniprot_id": "CAZA1_HUMAN", "id": "P52907-1", "name": "F-actin-capping protein subunit alpha-1", "aln": "MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPE-EADGGLK-SWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTTF-KALRRQLPVTRTKIDWNKILS-------YKIGKEMQNA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28495-1", "uniprot_id": "CAPZA_YEAST", "id": "P28495-1", "name": "F-actin-capping protein subunit alpha", "aln": "-------MSSSKFEEVINKIINDSPPGELREVYDDLIKITSEN--SKNTILDAIENYNVQNCIPIEVNG--NSVIISKYNKEG-AKFFDPVNSVIFSVNHLERKGLDIEPYEFTHAKIEKGQLKELHDKLHEYLLQSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWNGHWRSSYIYDLET--RELSGQISTQVHYYEDGNVSFQSGKDINQ--------SNVDDVVCTIRDIETNFENDLDLSFFDLNEKQF-KALRRRLPVTRSKINWGSAIG------SYRLGKNAAEGK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .. .: ::: .:****: :.::*: : :: :. * :: . *: ::* : *:::.:. * :*:* . : * : *..: * .. : *: *: : :. . . . . : * . .:: : *** *:*.: : : . :: * : *.*::. *: . **::: . . .. :. *.::: : . :.: : * *** *****: *:* :. ::* . ", "identical_positions": 43, "similar_positions": 101, "identity": "14.14%" }, { "cls_id": "homologset.agr.SGD:S000001491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU86-1", "uniprot_id": "D3ZU86_RAT", "id": "D3ZU86-1", "name": "", "aln": "------------------------------------------------------------------------------MLFSLNEWLWQETYWLPPNVTWAQLEDRD-------GLVFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFL-RMKQRPVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILY--HESWLWTPALCWENYPH-QTLNLALSWWYLLELGFY--ISLLITLPFDIKRKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQR---------GCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDS--------IKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRSDVEESDSSDDEAVSEGP-QLKNGMARGSRAAITNGPRSRAAACLTNGHTRAT-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6J1-1", "uniprot_id": "CERS4_MOUSE", "id": "Q9D6J1-1", "name": "Ceramide synthase 4", "aln": "------------------------------------------------------------------------------MSFSLSEWLWQETYWLPPNVTWAELEDRD-------GLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFL-RMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILY--HESWLWSPSLCWENYPH-QTLNLSLYWWYLLELGFY--LSLLITLPFDVKRKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRR---------GCDALFIMFALVFFYTRLIFFPTQVIYTSVYDS--------IKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEPVSEGP-QLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA82-1", "uniprot_id": "CERS4_HUMAN", "id": "Q9HA82-1", "name": "Ceramide synthase 4", "aln": "------------------------------------------------------------------------------MLSSFNEWFWQDRFWLPPNVTWTELEDRD-------GRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFL-TEGHRPKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLY--HESWLWAPVMCWDRYPN-QTLKPSLYWWYLLELGFY--LSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQ---------VCDALFLIFSFVFFYTRLVLFPTQILYTTYYES--------ISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPLQLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEC1-1", "uniprot_id": "A0AB32TEC1_DANRE", "id": "A0AB32TEC1-1", "name": "", "aln": "-------------------------------------------------------------------MCIPLINGFMQLEDNINRWLWREDFWLPPGVTWKDIAEGTS-----DGSRHPVPRDLLISFPLALGFIALRFVFERVVALPLSRRLGVRDRVRLHITPIPKLEAFYLQKKKTEPSQEDLQALVKLCGLSERQIQSWLRRRRIQDRPANSRKFSEASWRFGFYLIIFSAGLISLI--HTPWFWDHRECWSGYPA-QAVAEAQYWYYIIELSFY--LSLLLCVSVDIKRKDFQEQIIHHIATIFLIAFSYCANYVRVGTLVMLVHDSSDFLLESAKMFNYAGWRK---------TCDALFVVFAAVFLVTRLIVFPFRIVYTAVVDS--------LDVFSPYPGYYFFNGLLLVLQALHIFWAWLILRMVHKFVFLGKVERDERSDDESEPDEDDEVG---EEEEERSWEHKKGALNSKLASLANNCVLNNLTNQRQKMNSRTLKER-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BAR8-1", "uniprot_id": "A0A8M2BAR8_DANRE", "id": "A0A8M2BAR8-1", "name": "", "aln": "-------------------------------------------------------------------------------MDALSRWFWKQEFWLPPGIVWEDLEEMQ-------GSRRPMPRDLLLALPLALAFIMLRYAFERRVAFPLSRVLGVKDPVRLKVTPSPSLEAFYT-KNSRQPTQIEISGLVKQCGLTHRQVETWFRNRRNLDRPSNTTKFCEACWRFAFYLVAFTAGLLSLI--NTAWFWDQRECWRGFPR-QPLQELHYWYYMLELSFY--WSLLLCVSVDVKRKDFKEQIIHHFATIFLLGFSYCSNYIRIGTLVMLVHDASDFLLESAKMFNYAGWKK---------TCDSLFVIFAAVFLVTRLLVFPSKIIYTTLVLS--------MEVFEPFLGYYFFNALLLVLQALHIYWAYLILRMVYKFLFLGKLDKDERSDVETEPEEEEEEEKEEEEEEQRSWRKRKVVLDSRRAMLSSSCVLNNLTQQKADAQ-RRPKAR-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q924Z4-1", "uniprot_id": "CERS2_MOUSE", "id": "Q924Z4-1", "name": "Ceramide synthase 2", "aln": "------------------------------------------------------------------------------MLQTLYDYFWWERLWLPVNLTWADLEDKD-------GRVYAKASDLYITLPLALLFLVIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYQ-TSGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTV--DKPWFYDLRKVWEGYPI-QSIIPSQYWYYMIELSFY--WSLLFSIASDVKRKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDASDYLLESAKMFNYAGWKN---------TCNNLFIVFAIVFIITRLVIMPFWILHCTMIYP--------LELYPAFFGYYFFNFMMAVLQMLHIFWAYFILRMAHKFITGKLIE-DERSDREETE---------SSEGEETAAGAGAKSRLLANG-----HPILNNNHPKND----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G23-1", "uniprot_id": "CERS2_HUMAN", "id": "Q96G23-1", "name": "Ceramide synthase 2", "aln": "------------------------------------------------------------------------------MLQTLYDYFWWERLWLPVNLTWADLEDRD-------GRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYL-TSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIV--DKPWFYDMKKVWEGYPI-QSTIPSQYWYYMIELSFY--WSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKN---------TCNNIFIVFAIVFIITRLVILPFWILHCTLVYP--------LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVE-DERSDREETE---------SSEGEEAAAGGGAKSRPLANG-----HPILNNNHRKND----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1A3B0-1", "uniprot_id": "CERS3_MOUSE", "id": "Q1A3B0-1", "name": "Ceramide synthase 3", "aln": "------------------------------------------------------------------------------MFQTFRKWFWSERYWLPPTIKWSDLEDHD-------GLVFVKASHLYITIPYAFLLMVVRYFFEKFVATPLANALGIKKTQH-KIKPNAILENFFK-HSTSKPSHTDIYGLAKKCNLTERQVERWLRIRQKQNKPCRLQKFQESCWRFTFYLLITMAGAVFLY--DKPWAYDLWEVWNDYPR-QPLLPSQYWYYILEMSFY--WSLVFSLSTDIKRKDFLAHVIHHLAAISLMSFSWCANYIRSGTLVMFIHDISDIWLESAKMFSYAGWKQ---------TCNTLFFIFTVVFFISRFIIFPFWILYCTLILP--------LHYLEPFFSYIFLNLQLMILQGLHVYWGYFILKMLNRCIFTQNVQ-DVRSDNEEEE--------EEEEEEEAESTKGKETEYLKNGLGTNRHLIANGQHGR------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M5E6-1", "uniprot_id": "A0ABK0M5E6_RAT", "id": "A0ABK0M5E6-1", "name": "", "aln": "MGASGRAMAEWPGRMAARCRWDEHSSRKVTDIREHPHANLLPLSSAQTLHSVGLPRMHHCTACPAAFEAASSQGTGKRMFYRFRKWFWSERFWLPPTIKWSDLEDHE-------GLVFVKASHLYITIPYALLLLVVRYFFEKFVATPLANALGIQKAQH-KIKPNAILENFFQ-HSTSQPSHNEVYGLAKKCNLTERQVERWFRIRQKQNKPCRLQKFQESCWRFTFYFMMTVAGAVFLY--DKPWAYDLWEVWYDYPR-QPLLPSQYWYYVLEMSFY--WSLVFSLGSDIKRKDFLANVIHHLAAISLMSFSWCANYIRSGTLVMFVHDISDIWLESAKMFSYAGWKQ---------TCNTLFFIFAIVFFISRFIIFPFWILYCTLILP--------LHYLEPFFSYIFLNLQLMILQGLHIYWGYLILKMLNRCIFTQNIQ-DVRSDNEEEEDEEEEEEEEEEEEEEEENTKGKETEYLKNGLGTNRHLIPNGQHGR------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IU89-1", "uniprot_id": "CERS3_HUMAN", "id": "Q8IU89-1", "name": "Ceramide synthase 3", "aln": "------------------------------------------------------------------------------MFWTFKEWFWLERFWLPPTIKWSDLEDHD-------GLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVR-KVTPNTVLENFFK-HSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLY--DKPWLYDLWEVWNGYPK-QPLLPSQYWYYILEMSFY--WSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQ---------TCNTLFFIFSTIFFISRLIVFPFWILYCTLILP--------MYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQ-DVRSDDEDYE--------EEEEEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JXZ1-1", "uniprot_id": "A0A0G2JXZ1_RAT", "id": "A0A0G2JXZ1-1", "name": "", "aln": "-----------------------------------------------------------------------MATAAAEALGLLWGWLWSGRFWLPQNVSWADLEGPG------DGYGYPRARHVLSVFPLAAGLFSVRMLFERFIAKPCALRIGIEDSAVYQVESNVTLEKVFT-SISKYPDEKRLKGLSKQLDWDVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYFCIFCYGVRFLW--SMPWLWDTRQCWYNYPY-QPLSRELYYYYLTQLAFY--WSLVFSQFIDVKRKDFLMMFMHHLIAVTLISFSYINNMVRVGAIILCLHDSADSLLEAAKLANYARQER---------LCNTLFVIFGAAFMVTRLGIFPLWILNTTLFES--------WEIIGPFPSWWLFNGLLLILQMLHVIWSYLIARTAFKALVRGKVSKDDRSDVESSS----------EE-DETTHTNNLSGSSSSNGANCMNGRMG-GSHLAEEQGTCKAAGNLHFGASPRIHSCD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6K9-1", "uniprot_id": "CERS5_MOUSE", "id": "Q9D6K9-1", "name": "Ceramide synthase 5", "aln": "-----------------------------------------------------------------------MATAAAETLGLLWGWLWSESFWLPQNVSWADLEGPG------DGYGYPRAQHVLSVFPLAVCIFSVRMLFERFIAKPCALRVGIKDSPVNKVEPNDTLEKVFV-SVTKYPDEKRLKGLSKQLDWSVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTYYLCIFCYGIRFLW--SMPWFWDTRQCWYNYPY-QPLSRELYYYYITQLAFY--WSLMFSQFIDVKRKDFLMMFIHHMIGIMLTTFSYVNNMVRVGALIFCLHDFADPLLEAAKMANYARRER---------LCTTLFVIFGAAFIVSRLAIFPLWILNTTLFES--------WEIIGPYPSWWLFNALLLILQVLHAIWSYLIVQTASKALSRGKVSKDDRSDVESSS----------EEEDETTHKNNLSGSSSSNGANCMNGYMG-GSHLAEEQGTCKATGNLHFRASPHLHSCD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5B7-1", "uniprot_id": "CERS5_HUMAN", "id": "Q8N5B7-1", "name": "Ceramide synthase 5", "aln": "-----------------------------------------------------------------------MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPA------DGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFI-SITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLW--SSPWFWDIRQCWHNYPF-QPLSSGLYHYYIMELAFY--WSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLLEAAKLANYAKYQR---------LCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES--------WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSS----------EEEDVTTCTKSPCDSSSSNGANRVNGHMG-GSYWAEE----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZMG9-1", "uniprot_id": "CERS6_HUMAN", "id": "Q6ZMG9-1", "name": "Ceramide synthase 6", "aln": "-------------------------------------------------------------------------------MAGILAWFWNERFWLPHNVTWADLKNTE------EAT-FPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPNAILEKVFT-AITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLK--KTPWLWNTRHCWYNYPY-QPLTTDLHYYYILELSFY--WSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQK---------MCDLLFVMFAVVFITTRLGIFPLWVLNTTLFES--------WEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSS----------DEEDSEPPGKNPHTATTTNGTSGTNGYLLTGSCSMDD----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "----------------------------------------------------------------------------MDILNEFSNVFWSTHIWLPPNTTWADIAPGSR-----PDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYA--KSTRLDKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLW--DKPWFWDVKSCWYGYPH-QSISNDIWWYYMISMSFY--WSLTGTQFFDVKRKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQK---------LCDAIFAIFTVVWIVTRLGFYP-RIIYSSSVEA--------PRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSS-DSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27545-1", "uniprot_id": "CERS1_MOUSE", "id": "P27545-1", "name": "Ceramide synthase 1", "aln": "---------------------------------------------------------------------------------------------MAAAAATPRLEAPE-------------------------PMPSYAQMLQRSWASALAAAQGCGDCGWGLARRGLAEHAHLAAPELLLAVLCALGWTALRWAATTHIFRPLAKRCRLQ--PRDAARLPESAWKLLFYLACWSYCAYLLLGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYC-HSIYATVYMDSWRKDSVVMLVHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVANLGCLSFCFCWFWFRLYWFPLKVLYATCHCS--------LQSVPDIPYYFFFNILLLLLMVMNIYWFLYIVAFAAKVLTGQMRELEDLREYDTLE--------------AQTAKPCKAEKPLRNGLVKDKLF--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27544-1", "uniprot_id": "CERS1_HUMAN", "id": "P27544-1", "name": "Ceramide synthase 1", "aln": "---------------------------------------------------------------------------------------------MAAAGPAAGPTGPE-------------------------PMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQ--PRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYG-HSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS--------LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQVHELKDLREYDTAE--------------AQSLKPSKAEKPLRNGLVKDKRF--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28496-1", "uniprot_id": "LAC1_YEAST", "id": "P28496-1", "name": "Ceramide synthase LAC1", "aln": "----------------------------------------------MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMY-HSDLWFFNTKAMYRTYPD-FTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLA--------FFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILK-DDRSDSESDE------------ESDESSTTPTDSTPTKKDI--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : :: * : : : : : . *: . .*: : : *** **. : * *: . . * : * :* *. * * . :: : : .. : : :: * * : . . : ", "identical_positions": 18, "similar_positions": 43, "identity": "3.43%" }, { "cls_id": "homologset.agr.SGD:S000001492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0I8-1", "uniprot_id": "MRT4_MOUSE", "id": "Q9D0I8-1", "name": "mRNA turnover protein 4 homolog", "aln": "MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKKLRGEVGLLFTNRTKEEVNEWFTKYTEMDFARAGNKATLTVSLDPGPLK----QFP--------HSMEPQLR-QLGLPTALKKGVVTLLSDYEVCKEGDVLTPEQARILKLFGYEMAEFKVIIKYMWDAQSGRFQQMDDDLPESAPESEGESEEE-DDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWZ6-1", "uniprot_id": "A0A8I5ZWZ6_RAT", "id": "A0A8I5ZWZ6-1", "name": "Ribosome assembly factor mrt4", "aln": "-----------------------------------------------MRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKKLRGEVGLLFTNRTKEEVNEWFTKYTEMDFARAGNKATLTVSLDPGPLK----QFP--------HSMEPQLR-QLGLPTALKKGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDAQSGRFQQMDDDLPESAPESEGESEEEEDDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKD2-1", "uniprot_id": "MRT4_HUMAN", "id": "Q9UKD2-1", "name": "mRNA turnover protein 4 homolog", "aln": "MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGPLE----QFP--------HSMEPQLR-QLGLPTALKRGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33201-1", "uniprot_id": "MRT4_YEAST", "id": "P33201-1", "name": "Ribosome assembly factor MRT4", "aln": "MPRSKRSKLVTLAQTDKKGRENKERIFDEVREALDTYRYVWVLHLDDVRTPVLQEIRTSWAGSKLIMGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGLLFTDEDVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPMIHSLEPTMRNKFEIPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFGIAASEFKVKVSAYYDNDS------------STVESTNINME-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.. *::**.:* *::::**.**: ***.. .:***:**:*:** * .*****:. : *:*:*..*.. *::*...**.:*.:: * : *:* **:** :* :: :** :* * :*: * * **.**: * .** :** ** :**** :. :* :* *: ** . . ", "identical_positions": 71, "similar_positions": 62, "identity": "28.06%" }, { "cls_id": "homologset.agr.SGD:S000001493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E870-1", "uniprot_id": "TRIPC_MOUSE", "id": "G5E870-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR------------------------------------------SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPRAFQHIESFSETNKPHS-----------KSKKRHLDQ-------------------------------------EQQLKSAQLPSTSKAHTRKSV------AAGSSRNQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPIKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAIASASST-----VPAGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNQETVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANSNTSG------------YSELKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------LGSTTPASSGTATAATNASADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSAQSNSNNIEPAR---------------------------------TAGVSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKNEKDAVGREIRLKRFLHVFFSSPLP-GEEPVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGAGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------TKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIDIMRDKLLIAAREGQQSFHLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP64-1", "uniprot_id": "TRIPC_RAT", "id": "F1LP64-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR------------------------------------------SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPRAFQHIESLSETNKPPS-----------KSKKRHLDQ-------------------------------------EQQLKSAQLPSTSKAHTRKSV------AAGSSRSQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPTKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAVASASST-----VPAGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNQETVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANTNTSG------------YSDLKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------LGSTTPASSGTATAATNASADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSAQSNSNNIEPAR---------------------------------TAGVSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLP-GEEPVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGSGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------SKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMRDKLLIAAREGQQSFHLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14669-1", "uniprot_id": "TRIPC_HUMAN", "id": "Q14669-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPKALQHTESPSETNKPHS-----------KSKKRHLDQ-------------------------------------EQQLKSAQSPSTSKAHTRKSG------ATGGSRSQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPTKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAVASASST-----VPPGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNQEAVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANSNTSG------------YSESKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------MGSTTSVSSGTATAATHAAADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPAR---------------------------------TAGGSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLP-GEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------NKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVSNPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCR6-1", "uniprot_id": "TRIPC_DANRE", "id": "F1RCR6-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNSNPGGSLRRSQRNTAAAQPIDHTLAGRN-----------------------------------------SLSLSVGSLSIPDPDLEAAGTSGQQGR---REGSSTRALKRSSVSEPNI--TFSPSP-----------------AKRPKVVSSHFSDSSASGPSAPAISPEVTEPRKAPASVSTK-------------------------------------SKKRRLAAEPAPARALSKKSSSYPGPSGASSTPSQKRKKADATL-------------------------------------------------------LSSSSSSSLPSSSSAAGPLPPRSEASRAAKPTKLASKSAASAKAGCSTVTDSSS----------------------------------------------------------------------------------------------------------------------------------------------SSASSSSSSSSSSSAATGTNSCAPQGARLKQGKDQSKARRSRSASSPS-------------------------PRRSSRDKEQSKAAGSSKFDWASRFNSKVNLPKPKLSLPGSAKAETSS-----------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SCRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNQDGANSSAARTEETPQGASASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPFGPRMSQLFHRTIGSGASSKAQQLLQGLQATGDESQQLQAAIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHASRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQFIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASRDLLTNIQQLLVLTPPVLSSGMFIMVVRMFSLMCSNCPCLAVQLMKQNIAETLRFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPREGIFAVDAMLKKGSAQTTEGAIWQWRDDRGLWHPYNRIDSRIIE---------------------------QINEDTGTARAIQRKPNP--------------------------------LANPNTGG------------HLEVRRE---DARAQLMKEDPELAKCFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLRNHAVSSHIASMLSSQDLKIVVGSLQMAEILMQKLPDVFSVYFRREGVMHQVKNLAE---------SEVFLTSPPKACTSGTAS----------------LCTTT-ITTATTTAASNVTPDLGSPSFQHSM-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGKLGTQANSANSEPSR---------------------------------TAGVSGLARVPPKDSVSN-----------NRDKIKAWIKEQASKFVERYFNSES------------VDGSN---------------PALNVLQRLCTATEQLNLQMDSGVECLEEISSIVSESDVSSFEIQHSGLVKQLLLYLTSNSERDTISRDERIKRFLHVFFGCPIP-GQEPPGRLDPTENGPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGNG-----SRGSQALKFFNTHQLKCQLQRHPDCTNV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRIREEDEDSDDDGSDDEIDESLAAQFLNSGSVRHRLQFYIGEHLLPYNMTVYQAVRQFSLQAEEERESTDDEANPLGRAGIWTKTHTVWYKPVREDEEG--------------------------------------CKDAVGGKRGRAQTAPTKTSPRNAKKQDELWHEGVCPSVANPLETYLICD-PPEGITFDDPSMEVILLLRVLHSISRYWFYLYDNAACKEIIPTGEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTINRDELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSHDLVNIDPGVAKSIQHLEDIIRQKKRIEQDRSHTRETLQQALESLNMNGCSVEDLGLDFTLPGFPNIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSES----WDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN58-1", "uniprot_id": "Q9VN58_DROME", "id": "Q9VN58-1", "name": "E3 ubiquitin-protein ligase", "aln": "MAESVKSQSLSALTEGQHDDGGSTATSATLANKTSGTNTTSASNHSSQRRRNNNTNSNRNKSHHKNEKRNAPATSGPAVSSSVDVVPATSTASATSTRRSRSQGRHSSAAALSSKESQIPKRSVGAIRSPSSPAFNSIPVVSDQSLSPGSRKRQLNQHNNSNNKASSSHQSAPGGDQLVCAPLKKRRLQQSLGSGICEGAVEINLGAASFDHTPRQASGDCVAQRTRSKTISPEELPSTSSAAAARHHQIRPSASSTSFSSSHRNKRKASIGGSIAAVETTPHRGTAAARAGRSGNLLNYYRKTRKVSHTRSSQKSEKQSIPAEDTTANRNGSAGSGSSSKSGVIPKNRKSLRHSQQNLLDTEAAEVESAAAETGGEQQSEHGNLDVIDQLPTPEAGPNQSEASGIHNQSQLEADRQPVVQDEDDEEDDEEEEEEEEEEVGFYGIVNSAGSSYEEDTQIVAEEDEITTEEEVDDEDDDEIEEEDLSESEFAQQLIGELGGERQQPQRATNNAKKTKNNTPAVAAASTIKATTTATTSSGYQQRAAPHGQGAAPGAGGGGPRATRSSNSNSSNNVVDYSIMPHLTTVATTTPHALTPQQHQQQRQPPQPPSHQQQQVHQQQQPPQLLPTHQFAHLSSFVTPTAAAAAAAAAAHYPPASAAAAYFAQQQHHQHQHQHQQQHVQQAQAPQPHYYHSSVAVLHQPPPHHFTSTGAGPPPALFQQQAPPQLTRYTPATATTAATFVPPQQQQVVYNPQQQQHSSLRRSSRGKTGSCVSSAAAAQQQQHHQQQQHSSAAAAVQQQLLPPPGTYQYQQVGGNTVVVAVRHQQQLQQQQQQQQQLALHHQHQQQQHQQQQQQHQQQQHQQQQRATLVQPGFLFSYRSNQPQQQQQPAQQIHQGPKVTHSSAASDALTYSLMAQQPPSGPPHAGGQQITPGANSANLSIVAAALSAARDVGGGSDGGGSAGGATPATGASASSVGNTSAVGASSSSNSSAGQAASSNSNNVTATGSGSAPGGGPTSTGTTSGTQHGSGSGAAAAVDSESDDSEVGRLQALLEARGLPPHLFGALGPRVTHILHRTIGNSSSSKANQLLQGLQSH-DESQQLQAAIEMCQMLVMGNEDTLAGFPIKQVVPALIQLLRMEHNFDIMNNACRALAYMLEALPRSSGTVVEA--VPVFLEKLQVIQCMDVAEQSLSALEILSRRHNKAILQANGISACLTYLDFFSIVAQRAALAIAANCCLNMHPEEFHFVAESLPLLARLLSQQDKKCIESVCSAFCRLVESFQHDGQRLQQIASPDLLKNCQQLLLVTPAILNTGTFTAVVRMLSLMCCSCPDLAISLLRNDIAATLLYLLTGNAEPAAASATHVELISRSPSELYELTCLIGELMPRLPLDGIFAVDSLLDRPTLNTQDQVHWQWRDDRGSWHNYSTIDSRLIEAANQSSEDEISLSTFGRTYTVDFHAMQQINEDTGTTRPVQRRLNHNYVAPMSAGQDLTTTSAGSAAAGGASTSAAAAAASSNNNNNNNNNPPGNSVNLNQVKRRPSLDARIACLKEERGLAADFIKHIFNVLYEVYSSSAGPNVRYKCLRALLRMVYYAT-----------PELLRQVLKYQLVSSHIAGMLGSNDLRIVVGALQMAEILMRQLPDVFGTHFRREGVIYQFTQLTDPNNPICANPSPKPLSATATPTANAGGSQSAPASANSLQVNPFFMDSAPGLSSASTTPSSSKHQSYSVKSFSHAMNALTASAKGTPSGALDATSSSTTAGGYNYSSSAPSSSSGAPAAYFVTQQGDPRQYVHFQQPAVPAPPPQQELLPSGVQQQGQQVPQVIYQPHHQQPAHLVLASTSSGAASSSSSSSSSSSASALQHKMTDMLKRKAPPKRKSQSGGRAKSRQEDAAVAPAGSGPGGAPPSSSGSAMHELLSRATSLGSGNGGRSTPNSGGGSGSSKSRFNAGNSSNAGSSKSSFLASLNPARWGRQTHQNHHHHHQQSQQQHHGLSKDSGNSNSTGSGSGAGLAYTVSQHGAGSGAGGLNAAAVAASISKSISHANLLAAANRERARQWVREQAVDFVKRYTEQEAKRSKAASESGATQSGSSGVGLSSTGNTPLSTAGSTNVLERLSSILFKLNGSYHDCLDALLELKTILLESDISPFEVNHSGLIKAMLNYMTS--ETGLVERDARLRSFMHVFAGLPLEPLLQNVGQMPTIEPIAFGAFVAKLNGCVTQLEQFPVKVHDFPAGPGGR------SNQSALRFFNTHQLKCNLQRHPQCNNL-RQWKGGTVKIDPLAMVQAIERYLVVRGYGGIRAD----SDDDSEEDMDDNVAAVVLSQASFRHKLQFTIGDHVLPYNMTVYQAVKQFSPLVSEQPETDNESETLLGNASIWVQQHTIHYRPVEEEVTSGAAAGAASSSSSCSSGVQKQQSSSSSASSCVNATSSCSSSSGVASGGGSLTKKAHKSSSKFMRKKTELWHEGIAPVVISALKPFLSSSLPADVVTVQDASLDALCMLRVIHALNRHWDHLYGCVVRQNIIPQSDFIHPKIMAKANRQLQDPLVIMTGNLPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRALQRLLDTTP-DLNAAESSE-RVAPRLDRRKRAISRTEILKQAEHILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSYKQNSVTIVDVVKANSAVLHIEDALEATTTDQNTPAVAGASLVSSSTTTTTTTAQQHQHPPTRSSSRSHVLRSGAGQQPVEHSSSSAGANENALNMVIAQQFSDTNSANPAAIDNPSSTTTATTVVQHNTTTNNSSIITTTTTTSYVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIELCRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33202-1", "uniprot_id": "UFD4_YEAST", "id": "P33202-1", "name": "Ubiquitin fusion degradation protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSENNSHNLDEHESHS--ENS--------------------------DYMMDTQVEDDYDEDGHVQGEYSYYPDEDEDEHMLSSVGSFEADDG------------------------------------------EDDDNDYHHEDDSGLLYGYHRTQN-----------------------------------------------------------------GSDEDRNEEEDGLERSHDNNEFGSNPLHLPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILETFAQRLEQRRQTSEGLG-------------------------------QHPVGRTLPEILSMIGGRMERSAESSARNERISKLIENTG-----NASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLIG------NIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISYIDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIRTDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIERIVQLVSIQDTPLEN--KLKCLDILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPNAGLHETLIYVPNSLLISISRFIVVLFPPED-ERILSADKYTGN--------------SDRGVISNQEKFDS-------------------------------------------------------------------------------------------------------------------------------LVQCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKETASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLSV---------------------------------------------------------------DFNNIDLKEDG-----------NENISLSD-----------------------------------------------------------------------------------------------------------------------EEGDLHSSIEECDEGDEEYDYEFT----------------------------------------------------------DMEIPDSVKPKKISIHIFRTLSLAYIKNK-----------------------------------GVNLVNRVLSQMNVEQ-----------------EAITEELHQIEGVVSILEN------------------------------------------PSTPDKTEEDWKGIWSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITS----STVSHFILAKSFLEVFEDCIDR-------------------FLEILQSALTRLENFSIVDCGLHDGGGVS------------SLAKEIKIKLVYDGDASKDNIGTDLSSTIVSVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKN-FDFFYDNEKVDMESTVFGVIFNTFVRRNRDLKT------------LWDDTHTIKFCKSLE---------------------------------------------------GNNRESEAAEEANEGKKLRDFYKKREFAQVD------------------TGSSADILTLLDFLHSCG---------------VKSDSFINSKLSAKLARQLDEPLVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRNDEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNS-----------------------------------------------------------------------------------------------------------------YSYRSEMDVD---------------------TTDDYITTLLFPEPLN---PFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKD---------------DNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFG-RVEED----WSMATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::* . * : . : : . :: .* : . : . :: . .: ... : .: : . . * . . * ... . : .: ::: .* . .. . *:::::..* . ::: .::: : *::: :* :: * :. :.*:: :..:::: :*.*.: ::*. *.* . .*: :*:: ** *. :*:*** * ::* :** *.: **::. :: : :::*::* *** *:**.:*.* .: .::*: :.: ** * ::: .: : : : . * : :: : * **: . **: : . *.. : :::::. .. *: .* .: : . : *: . . * .:: :* *:* : *::.* . .*** . :** ::: :: :* *:*:.:*. ** * *:**:: :*: .:* : .:*: . .*: ::**.*.: ::: :::.::* ::***:: ...*: . . .:.. . :. : :. : * : . .: *::* . : : * . : . .:.: : *: .: * . . . . .: : : : *:* **. :*: . : :** . : : : *:.** . :: ::..::::*:*.: .: * * : : ::* : ... *: : .. *.:. :* . :::.:* * : . .*. : * . *. :: ::* .:. : : **: .: : . : :: :* . **: : * * ... :* ::::. . * ..* : : :* .:*: . : ..**:.*: ** ***::***: :* :* * : **:***:** ::: *:*. .* :* :.. . : :.. : *: *:* :.* :: . ::.. * * :***:*::*.******* ***::** : * .* :*. .. . . *. **. *:. .: * * :**.::*::::* *::*: :. *:. : . . : . : : :. : : : . :. .: .*.* *.:** :*** ** : .:. *:.:*: * * :*: :*:.:: :**..**. :: ::*:** :: : *. * ..:**: ** :: : .:::::. .::* ****:****:** ***::*.* :*:* * :. ..:::*******.******.*:* ::**.:* * .** :* **", "identical_positions": 268, "similar_positions": 535, "identity": "8.46%" }, { "cls_id": "homologset.agr.SGD:S000001495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALK3-1", "uniprot_id": "A0A8I6ALK3_RAT", "id": "A0A8I6ALK3-1", "name": "Pre-mRNA-processing factor 40 homolog B", "aln": "---------------------------------------------------------------------------------------------------MMPP---------------------------PGLPPP---FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVPGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSALKSKAELLLSQCPWKEYKSDTGKPYYYNNQSQESRWTRPKDLDDLE------------------ALVKQESAGKQQTQQLQTLQPQPPQP--------------------------------------------DPPPIPPGPIPVPMALLEPEPGRSEDCDVLEAAQPLEQGFLQREEGPSSS-TGQHRLPQE--------EEEAKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVT-DPRYSALPK-LSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGDLEVWA--VVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-----FAQDQQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQP----GSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVN----TAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGRKHHRKRSHTPSGSESDEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGPGSPSSHLLLGSDHGLRKTKKPKKKTKKRRHKSTSP-----------DSETDPEDKAGKESEDREQEQD--REPRQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDHQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W14-1", "uniprot_id": "PR40B_MOUSE", "id": "Q80W14-1", "name": "Pre-mRNA-processing factor 40 homolog B", "aln": "-----------------------------------------------------------------------------MMP-----------------PPFMPP---------------------------PGLPPP---FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSQESRWTRPKDLDDLE------------------ALVKQESAGKQQTQQLQTLQPQPPQPQP------------------------------------------DPPPIPPGPIPVPMALLEPEPGRSEDCDVLEAAQPLEQGFLQREEGPSSS-TGQHRQPQE--------EEEAKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVT-DPRYSALPK-LSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGDLEVWA--VVPERERKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-----FAQDQQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQSFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQP----GSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVN----TAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARETEREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHRKRSHSPSGSESDEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGPGSPSSHLLLGSDHGLRKTKKPKKKTKKRRHKSTSP-----------DSETDPEDKAGKESEDREQEQD--REPRQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDHQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NWY9-1", "uniprot_id": "PR40B_HUMAN", "id": "Q6NWY9-1", "name": "Pre-mRNA-processing factor 40 homolog B", "aln": "-----------------------------------------------------------------------------MMP-----------------PPFMPP---------------------------PGIPPP---FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE------------------VLVKQEAAGKQQQQLPQTLQPQPPQPQP------------------------------------------DPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSS-SGQHQPQQE--------EEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVT-DPRYSALPK-LSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWA--VVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-----FAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQP----GSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVN----TAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSH-LLGADHGLRKAKKPKKKTKKRRHKSNSP-----------ESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDHQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1C7-1", "uniprot_id": "PR40A_MOUSE", "id": "Q9R1C7-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "-----------------------------------------------------------------------------MRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQR-ANMPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAA---NANTSTTPTNTVG-SVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANTTAIQDLSGDISSNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQP----GSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSESDDDDS-----HSKKKRQRSESHSASERSSSAESERS----------------------YKKSKKHKKKSKKRRHKSDSP-----------ESDTEREK--DKKEKDRDSEKD--RSRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75400-1", "uniprot_id": "PR40A_HUMAN", "id": "O75400-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "-----------------------------------------------------------------------------MRPGTGAERGGLMVSEMESHPPSQGPGDGERRLSGSSLCSGSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQR-ANMPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQP----GSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDS-----HSKKKRQRSESRSASEHSSSAESERS----------------------YKKSKKHKKKSKKRRHKSDSP-----------ESDAEREK--DKKEKDRESEKD--RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZVY5-1", "uniprot_id": "A0A8I5ZVY5_RAT", "id": "A0A8I5ZVY5-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "MQATPSEAGGESPQSCVSVSRSDWTVGKPVSLLAPLIPPRSSGQPLPFGPSGRQPLRSLLVGMCSGSGRRRSSLSPTMRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQR-ANMPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE------------------AMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAA---NANTSTTPTNTVG-SVPVAPEPEVTSIVATAVDNENTVTASAEEQAQLANTTALQDLSGDISSNTGEEPPKQETVTDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPVFSLGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDS-----HSKKKRQRSESHSASEHSSSAESERS----------------------YKKSKKHKKKSKKRRHKSDSP-----------ESDTEREK--DKKEKDRESEKD--RSRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VQK5-1", "uniprot_id": "Q9VQK5_DROME", "id": "Q9VQK5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MNVP---------PSVGNGGAPPGRG-IGYTP-----PGAIVPQFP---------PPGFGAPPPPELAAAFGVMATS---TEWTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHNQCPWKEYRSDTGKVYYHNVATKETCWEPPPEYVDMK------------------AKAKAEEAAAAAKAVAAMTSSSLAGMVPP----------------------------------------AALASILPAALPVAPRLPTPEIHSPLTPSSNENSSSAMDQAMA------ATLAAIEVPQQN----------AKKDDKSESAVVFKDKREAIESFKELLRDRNVPSNANWDQCVKIISK-DPRYAAFKN-LNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMSSDKMNSQMKYFRCEEVFAGTRTWT--AVPEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGELLESMTSINHATTWSEAQVMLLDNVA-----FKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEEREREKKRMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELYPIISADLRFSAMLGQS----GSTPLDLFKFYVENLKARFHDEKKIIREILKEKAFVVQAK----TSFEDFATVVCEDKRSASLDAGNVKLTYNSLLEKAEAIEKERMKEEVRRLRKLENEIKNEWLEAN--VSVAEPYESAKKLVEHLEAFALYEKEIGVEKIWEDFVKESED-ACSHHHSRSRKSKKNKKHKKRVRSVSRSDIENEHIEVE----KSKRRRSKTRSHSLTSIG-SIESEKL----------------------LKKKKKRKNKLRGSSCESDVPGIQSPGTQALLQNDSNSHSPAKKKKKEKRAKKD--KRHNRHNRSGTPLSPAQSVESSGSRNEELTLSDGELESKRAALLAQLSEQLDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33203-1", "uniprot_id": "PRP40_YEAST", "id": "P33203-1", "name": "Pre-mRNA-processing protein PRP40", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIP-------------------------AFEKKVEPIAEQKHDTVSHAQVNGNR---------------------------------------------------------IALTAGEKQEPGRTINEEESQYANNSKLLN-------------------------------------VRRRTKEEAEKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVNTIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVP--IKIKANTRWSDIYPHIKSDPRFLHMLGRN----GSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIEKVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKKHYFWLLL----------------------------------------------------------------------QRTYTKTG----------------KPKPSTWDLASKELGESLEYKALG----------------------DEDNIRRQIFEDFKPESSAP---------------------------------------------------------TAESATANLTLTASKKRHLTPAVELDY----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.* ..** **** *:* ****. * : * * : ** :: ** **:* ::*: * * . * . : . * :. : :.:* : * :*::. * *. .:.: :. : . **** . . :*: *: * : :: : : . .: *: ::::* . .::. :: .:. :. : .: * : : ::* : * . :**. : *: : : * . *:.: . . *: * * . : : : : :**.* : : :.::*.: ::: :. * ::* *: * :* .: :: : : * ::** :.:* ** ***: **: **** :*:: : . ::.* :: * :: * : : ::: :: :: :* ::.* :.*::: : :: ::* * :.: : : *: : :. : : . . : .. . * : : : :: . :* * . *: : :: : :*. ", "identical_positions": 93, "similar_positions": 194, "identity": "8.47%" }, { "cls_id": "homologset.agr.SGD:S000001496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59998-1", "uniprot_id": "ARPC4_HUMAN", "id": "P59998-1", "name": "Actin-related protein 2/3 complex subunit 4", "aln": "MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVR-SSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVE---------------------------------------------GYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABZ3NNN1-1", "uniprot_id": "A0ABZ3NNN1_RAT", "id": "A0ABZ3NNN1-1", "name": "", "aln": "MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVR-SSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEVLKGMSAPCQVSLVTWQTPSANTPSVSLCVLHPAPSPHSNLGATRGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59999-1", "uniprot_id": "ARPC4_MOUSE", "id": "P59999-1", "name": "Actin-related protein 2/3 complex subunit 4", "aln": "MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVR-SSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVE---------------------------------------------GYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VMH2-1", "uniprot_id": "Q9VMH2_DROME", "id": "Q9VMH2-1", "name": "Actin-related protein 2/3 complex subunit 4", "aln": "MAATLKPYLTAVRHSLTAAMCLQDFPSQVVERHNKPEVEIC-SSKELVLTPVVVSRNEREKVLIEPSINSVRVSIAVKQADEIERILCHKFTRFMMRRAESFVILRRKPIE---------------------------------------------GYDISFLITNFHTEQMYKHKLVDFVISFMEEIDKEISEMKLAVNARARTCAEEFLKRF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33204-1", "uniprot_id": "ARPC4_YEAST", "id": "P33204-1", "name": "Actin-related protein 2/3 complex subunit 4", "aln": "MSQSLRPYLTAVRYSLEAALTLSNFSSQEVERHNRPEVEVPNTSAELLLQPMHISRNENEQVLIEPSVNSVRMSLMVKQADEIEQILVHKFTRFLEQRAEAFYILRRVPIP---------------------------------------------GYSISFLITNKHTESMKTGKLVDFIIEFMEDVDKEISEIKLFLNARARFVAEAYLDEFVY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :*:***:*** :* **: *.:*.** *****:****: :* **:* *: :****.*:**** *:****:*: ********:** *** **: *** * **** *: **.******* ***.* . *****:* ***::******:** :***** ** :*..* ", "identical_positions": 107, "similar_positions": 34, "identity": "49.54%" }, { "cls_id": "homologset.agr.SGD:S000001497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7S4-1", "uniprot_id": "D4A7S4_RAT", "id": "D4A7S4-1", "name": "", "aln": "----------------------------------MGVPKRKASESPGGAASPAG-TSKRTRAEEFTGVRFKTQLKDAQGPGPALEAFVS---AAKQLPQEDMCDVVEGYIKIS-----------------MECAEIFQLLSGEKRP---------ESEVLLIFQAFEAILLRTASDLTHFHVVGTNIVKKLLNN------------------HMKLLCESLYASGYRMARACLDLMTAVVTQGPEAARDVCSCFDLNKKALYALVTKRDSKG----VHDVRLAYIQFALSFLIAGDDNTIGQVLEI-KEFIPCIFSSGIKEDKISTINILLSTLKTKVIHNKNITKTQKVRFFTGQLLNHIAALYNWN---GVSDIVPENPESTEMSAEEAGKAMVRDLVHNFLIDLCCSRKHGISFYDASLGTSGRGGNLTLLHFLLSLKTAAGDELVASLVVSILKVCPDLLTKY--FREVTFSFLPRVKSTWLNNVKLLNKIYEAQPEISPAFWTREFIPLPRLLAMVMVTTVPLVCNKIMFTQALNLDSIPVKQSALSLISIILKRALKTVDHCLDKEIWQDSDVYTAEMMEEFVQLFREALSKILPDLNTVIWVWQSFKKQEIKENHEKGKKSSSKTPAASKAVHRDDAETILLKSVLLQVICLYQQVVPHVVTQYNFDFSKLLKGIISEQGPAEEAPPILQHHMLKVALELPANKFLWLKAQE--GPEAEIVGGERSVFYLLMKMFVNSSHLQLKLSTQRLIMKILRDTGVFEHTWRELELWLERLDSTAEKHKETVIQFLERILLTLVVNPYSYTDKASEFVQEASTLQGAVGKQDADDVSIPISHIDDVLDMVDVLVEGSEGLDEDIGFLLNEDMILLTFPFSALVPAALEARNKLLLGTECEAGESIVAYMTAVLTDILHTQRDPLALCLLLQSYDKFEPASLL-CCQQLAQFHRYYSLWIPEQAQEALPLQVSGTSGPYTPPSSACFSTLLQTAYESQTLGDKNVQAKLLAAVPCLPLQHMLRSAKQVLLYLKSTVENFSQLGKSVGPTLLQFLLGLLKHLVIHSEQLDTQNQQKLEAARAESDLFLDMESVASLELATDKTVEELLVAILKHPTLETWFLALEQKALPPHTLSPVLVKLLAAQFSAGVLQLLVASSPILHKLGQLGLLAKYSEAITQSVLRELRTRTVN-SAMTPKTLPQLEALRELHPYMEGVQIREVTLALLGLPEAHLLTQQGTQCPGKERQLSSLGKTLVQLLTSSHQNRLQSSELLWCAEYVRGLGALLPTLAEQELDTVFLQTLQKDPVLAPVVPADLLEYCLVRR--TKAALDIASLLLQYSSTHLLKFELWCGQPGVGPSLQEHLDDFFPLIHVYLQHRMQGSFMRPTEVSSAVTPVLR-ALWRQVRDRFFHIAGPSKHALHLEALAQLIPFARTKDLRVLMDHLPNLLRTLSNHKSWIVADSVSAALAESAEELASWRKTLLRSCIQWLAVSFSGREPENENTQEQEKTMLLRLSELLHAVKEVDPG-DWQQFVKTGLKFRYQDLTFLRTLLDATK--------LLYSPESSGHTKLVQLSVMHMMLTQHSLFLPTMLTSKEEETPDSPVKETLLDLMSTVVRMCPSVCESSHFAVLLGTYSATLSILDQKILLLLRAYEQHSLSLISFRVLLWGPAAVEHHKTCRSLG----KSLWQQPSVGDILRLLDPDRMMQTILHFPQYRRLLHTEDTGEPQVFKDKTARVDLSG-------------------------------LYDPCFLLHLFGELTRPEFVVDCRKFLDSNALGLTVAALSSYDPQMRAAAYYVLAAYYSHLEGARFREQSQVLYLLDVVRNGIQAPN-------------LRLPFTVALFIAKAAAQILRPEEHMYWKISKFLLSHENLNMNKLPGFYQFFYSSDFQQKTEQEWVLEILRQGIRDKHCYELCSRRGVFHIILSFFSSPLCDEVAQNWILEILQNVAHIPRSAYEVIRDYSLLTWILHIL-ESRFIETQLLSNVISLLHTLWVTNLGSRAAEERSQLPCQTDCHESEKTLALHMVNEFLYVLVALTKHLRPTLASTQLMDFFWTLESVLSYRATVIKIFKDMGRFTVNQVTLSTKDVLVLLHKWSLIERDTKLQGELKAIIEQHQAKDLMKMLKDKHRPLGAARAKGPRGREKRRREREEETAEPQLEASTLEKCKDLLRATLTHWGPAVPLPGPTQESVGQAIPKSKALGSAHAAVSLVAGWVLRSLAERPLSRAEVTRLLDWLKSHILPQPMVVADLLRDSAVKTGIFKLYSRHCNAQGLVGPAQDVACKFSMVMLQLLVAQGRTPSPFHSVAEALCLDSLNEKDEAKRAPAAFLVSLYIKDIWLGAQQPDTFLAHIQTVCEASKDMALGESEALVVLCRDVGSSAQSLTHSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571H0-1", "uniprot_id": "NPA1P_MOUSE", "id": "Q571H0-1", "name": "Nucleolar pre-ribosomal-associated protein 1", "aln": "----------------------------------MGVPKRKASEGPSSAASPAG-TVKRTRAEEFTGVRFKTLLKDAQGPGPALEAFVS---AAKKLPQEDMCDVVEGYIKIS-----------------MECAEIFQLLSGEKRP---------ESEMLLIFQAFEAILLRTASDLTHFHVVGANIVKKLLYN------------------HMKLLCESLYASGYRMARACLDLMTAMVTQGPEAARDVCSSLDLNKKALFALVTKRDSKG----VHDVRLAYIQFALSFLIAGDDNTIGQVLEI-KEFIPCIFSSGIKEDKISTINILLSTLKTKVIHNKNITKTQKVRFFTGQFLNHIAALYNWN---GITDVTPEKPE---ISAEEAGKAMVRDLVHNFLMDLCCSRKHGISFYDASLGTSGRGGNLTLLHFLLSLKTAAGDDLVASLVVSILKVCPDLLTKY--FKEVTFSFLPRVKSTWLNNVKLLNKIYEAQPEISPAFWTREFIPLPRLLAMVMVTTVPLVCNKIMFTQALNLDSIPVKHSALSLISDILKRALKTVDHCLDKETWQDSDVYTAEMMEEFVQLFREALGKILPDLNTVIWVWQSFKKQEIKEDHEKGKKSSSKTPAVSKAAQHDVAETILLKSVLLQVICLYQQVVPHVIMQYNFDFSKLLKGIISEQGPSQEVPPILQHHMLKVALELPANKFLWLKAQE--GPEAEIIGGERSVFYLLMKMFVNSNHLQLKSSTKLLIMKILRDTGVFEHTWRELELWLEHLDSTAEERKEAVIQFLERILLTLVMNPYSYTDKASEFVQEASTLQASMGKQDADDVSIPISHIDDVLDMVDVLVEGSEGLDEDIGFLLNEDMILLTFPFSALVPAALEARNKLLLGTDCEAGESIMAYMTAVLTDLLHTQRDPLALCLLLQSYDKFEPVSLL-CGQQLAQFHRYYSLWIPAQAQEALPLQVSSSSGPCTLPPSSCFSTLLQTAYESQTLGDKSVQAQLLAAVPSLALQHMLRSAKQVLLYLKSTVENFSQLGRSVGPALLQSLLGLLKQLVIHAERLDAQNQQKLEAARAESDLFLDMESVASLELATDKTIEELLLAILKHPTLETWFLALEQKALPPHTLSPILVKLLAAHFSAGVLQLLVASSPILHKLGQLGLLAKYSEAITQSVLIELRTRTLN-STSTPKTLPQLEALRELHPYMEGVQIREVTLALLALPEAHLLTQQGTQSLGKERHLSSLGKTLVQLLASSHQDQLQSSELLWCAEYVRGLGALLPTLAEHELDTVFLQTLQKDPVLAPVVPEGVLEYCLARR--TQTALGIASLLLQYSGTHLVKFELWCGQPGVGPTLQEHLDDFFPLIHVYLQHRAQGSFMRPTGVSSAVTPVLK-ALWRQVRDRFFHITGPSKDALHLEALAQLIPFARTKDLHVLMDHLPNTLRTLSNHKSWTLADSVSAALAESAEELGSWRKTLLRSCIQWLAVSFSGREPEDENTQEHEKAMLVRLSELLHAVKEVDPG-DWQQFVKTGLKFRYHDLTFLKTLLSATK--------LLYGPESSGRTKLVQLSVVHMMLTQHSLFLPTMLSSEEEETPDSGVKETLLDLMSTVVRLCPSVCQSSHFAVLLGTYSATLSVLDQKILLLLRAYEQNNLSLISFRVLLWGPAAVEHHKTCRSLG----KSLWQQPSVGDILRLLDPDRMMQTILHFPQYRKLLPTEDTGEPLVFKDKTARVDLDS-------------------------------LYDPCFLLHLFGELTRPEFVVDCRKFLDSNALGLTVAALSSYDPQMRAAAYYVLAAYYSHLEGARFREQSQVLYLLDVVRNGIRTPN-------------LRLPFTVALFIAKAAVQILKPEEHMYWKISKFLLSHENLNMDKLPGFYQFFYSSDFQQKTEQEWVLEILRQGIRDKHCYELCSRRGVFHIILSFFNSPLCDEVAQNWILEILQNVAHITRSAYEVIRDYSLLTWVLHIL-ESRFVETQLLSNVISLLHTLWVTNLGNKAPEERSQPPGQVGSQESEKMLALHMVSEFLYVLIALTKHLRPTLASAQLMNFFWTLESVLSYRATIIKLFKDMGRFTVNKVALSTKDVLILLHKWSLIERDTKLQGELKAVIEQHQAKDLMKMLKDKSRPVVAAQARGPRGR-KRRHGGLEETAEPQLEASCLEKCKDLLRATLTHWGPGDPLPGPTQGSVGQTIPKSKTLSSAHAAVSLVASWVLRSLAERPVSRAEVTRLLDWLKSHILPQPMVVADLLGDSAVKTGIFKLYNHHCSAQGLVGPAQDVACKFSTVMLQLLVAQGRKESPFHSVAEALCLDSLNEKEEAKRAPAAFLVSLYVKDMWLGAQQPDTFLAHIRMVCEAAKDVPLDEPEAIVVLCRNVDSSAQCLTRSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60287-1", "uniprot_id": "NPA1P_HUMAN", "id": "O60287-1", "name": "Nucleolar pre-ribosomal-associated protein 1", "aln": "----------------------------------MGVPKRKASGGQDGAASSAG-AAKRARKEELTGVRFKAQLKDPQGPGPGLEAFVS---AAKKLPREDVYDVVEGYIKIS-----------------VECVEIFQLLSGEKRP---------ESETMLIFQVFEAILLRTASDLSHFHVVGTNIVKKLMNN------------------HMKLICESLYASGYRLARACLSLMTAMVTQGPEAARDVCSHFDLNKKTLYTLVTKRDSKG----VYDVRQAYVQFALSFLIAGDDSTIVQVLEV-KEFIPCIFSSGIKEDRISTINILLSTLKTKVVHNKNITKTQKVRFFTGQLLNHIASLYNWN---GITDVNPENVK---VSAEEAGKTMVRELVHNFLMDLCCSLKHGINFYDASLGTFGRGGNLTLLHFLLGLKTAADDDLVADLVVNILKVCPDLLNKY--FKEVTFSFIPRAKSTWLNNIKLLNKIYEAQPEISRAFQTREFIPLPRLLAMVMVTTVPLVCNKSMFTQALNLDSTSVRHTALSLISVILKRALKTVDHCLNKEVWQESGVYTAVMMEEFVQLFREALSKILPDLNTVVWVWQSLKKQETKQDDKKGQKRSDGPPAACDAHQCDDAETILLKAVLLQVICLYQKVVPHVVMQYNFDFSKLLKGVISEQGLREEVPPILQHHMLKVALELPASKFLWLKAQE--GPDAEIIGGERSVFYLLMKMFVTSSHLQLKSLTKLLIMKILRDTGVFEHTWKELELWLEHLENTMEEDKETVIQFLERILLTLVANPYSYTDKASDFVQEASMLQATMTKQEADDMSIPISHIDDVLDMVDVLVEGSEGLDEEIGFTLSEDMILLTFPFSAVVPAALEARNKLLLGTGNEAAENVVTYLTAVLTDLLHTQRDPLALCLLLQAYDKLEPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQAQGSPSPPALPLASSFTALLQAAYESQALRDEHIQVQLQATMPHLSMQQVLLAAKQVLLYLRSTVENFGQLGRSVGPPLLQLFLDLLRRLVVHCEQLDAQNQQRCEAARAEADLFLDMESVASLELANDQTLEEVLVAILRHPTLEGWFLALEQQALPPHTLSPVLVKLLATHFSAGVLQLLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEALQELHPYMEGAQLREVTLALLSLPETHLVTQQPTKSPGKERHLNALGKTLVQLLTCSPQDQLQSGELLWSSEYVRGLGALLPTLAVDELDTVLLHTLQRDPVLAPAVGADLLDYCLARR--TQAALSIAALLLQESCTHLLWFEQWCLQAGPGLGLQGDLDDFLPLIHVYLQCRTRSHFTRPAGVSSAVIPVLRKTLWRQLQSRLLSTDSPPASGLYQEILAQLVPFARAKDLSVLMDRLPSLLHTPSSHKRWIVADSISAALEGSAEELCAWRRTLLESCVKWLIVSFSGGQQDDDNTQNQEKEMLLRLNALLHALNEVDPG-DWQKFVKKGLKFRYQDHTFLKMLLTAVQ--------LLYSPESSVRTKLIQLPVVYVMLMQHSLFLPTLLTSDGEESPDSQVKEALVDLMLTVVEMCPSVCESSHFAVLLGAYGATLSVLDQKILLLLRAYEQNKLSLINFRVLLWGPAAVEHHKTCRSLG----RSLWQQPSVGDILRLLDRDRMMQTILHFPQNRRLLPPEDT-QELIFKDK-SRVDLDG-------------------------------LYDPCFLLQLFSELTRPEFVVDCRKFLDSNALGLTVTALSSYDPQMRAIAYHVLAAYYSHLEGARFQEQSQLLYLLDVVRNGIRTQD-------------MRLTFTLALFIAKAALQILKPEEHMYLKVSNFLLSHEYLNMDKVPGFYQFFYSSDFEQKTEQKWVFGVLRQGIRDKQCYELCARRGIFHIILSFFHSPLCDEAAQNWILEILQNAAQVARSAYEIIRDYSLLTWILHIL-ESKFLETPLLSNVISLLHTLWVTNLGDKAVEWESQRLCQPSSQEPAKRLALHLVNEFLYVLIVLMKHLRPTLAPVQLTNFFGTLDSVLRYRATVIQAFRDMNRFTVNETVLSTKDVLVLLHKWSLIERDLKLQEDLRAAIEKAQARELMKMLKDKNKPVMPARAKGPRGR-KRRPGEAEEMADPELMASTLETCKGLLRSILTYWRPVIPGPDPTQEPVDSASPESDAPGPVYAAASLAVSWVLRSVAEHPLSRAEAAGLIGWLKSHILPHPVVVADLLKDSAVRSSIFRLYSRLCGAEGLAGPVQEVACLFNTVMLQLVAAQGRAGSPFHPAMEALSLSSLSEKDEATQASAAFLVSLYIKDIWLGAQRPDTLLTHVRMVCEAADDAPSSEEEAIVVLCKDAASAASDA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VD07-1", "uniprot_id": "Q9VD07_DROME", "id": "Q9VD07-1", "name": "Nucleolar pre-ribosomal-associated protein 1", "aln": "MAIQPNRRKRRHEETTAEQEDEGEVEVPKKLAKESDTPKKKKKKDKTKESFDES-TLESTETDPADSTPSKKKSKKTKTSDTSVEQQVEVEMAEDEISRDSGIDPEESRIHFPNDFKMMHFRTKLRGNNFITELRHFLHMCSTTRPKLAAKYIEKRGKPLELAEAFERIDKTNLFHVDYLTEALHRVLMEILTNQKSHMESAVHGCRYFLKVHGGVLENQMKSMQLGHRRNALKLLTAIVCVEPQLARQVLNSYDVLSNVTVTQKLLSHEKSEYQCEDTVRKAFILFILAFLVEGNTLLIRNILDR-GQLIG-VLAKGLVYDDHVTVCVVLNALRQYVLENPEIQKTKKVLVFDLECCKNLRRLYDWEGPMGLKVMFAKSKHVSKIPPNPQEAEAVSAAVHELLLVLLTSRKHGICFDAMTH--YRQKQNKLQGRLLGSLFKPYDNPRKVDLVIQTLTACPDLGRNT--VRNCSSLLSP-VKTKPKDLPIAVAFLAQIINAVPPSALSAAFDKMTLTDFSFWIKELCLPIEALLHITGKKYLSDPDFNLRLAVLRLLLS-MMKQYSNYMNAIAVREQSKKAGNSLRKFKFDLLNHLLVHFPTIESILYSLYMFIKQKNVEG-------------------VNVLESLSITLDLVMLLCKENRAFVNKTSQI-LDYLDVLRPLYETDFDKLNQP----EELLKIQLELKSIKTILLLFPHSLNPTQPLFG---NVFKSFIKAYMLE-EKSIKSESGNILSRLFQNTGMFDSCRHEINIWIEALIGFG----PATVTNVVEILLTILCLDWRQIELPEQSVTDTAIITKNLSK-----------------------------LFAQIEQGQTVQAYVETLTLSKMMPLLLKG---------VELEEPYDEYVELVFVLLFHYHSKPEIVLQMYEDN--------------LSKHTNYMKSWLPGE----------GNGKPKKLPHLIFDKWPLLKQMRKVSTESENMSFEQVFKMDDTENNFELQLEEGQTMLLHSSLGNPRRN-----MIYVQDLLFVFSHFFTSQKLSKPQAELTADFLIKFLQIASQVDGPEEVQESDDEQQDENFTQSMLHYIFN-------------HRLWQLHPTELLSETSESRLNYVIFLRRLMEHCRSLPRFETYTANYRLHLIKTLDIALDT----PVDQLGNQQQLDECVKLVDSFEFNSDQCSQMLDLLTTKVQAKDCIPNGKPNHYFDLLLRLLGRLNTLKEPIDCGKSFKLILTFYKDFGELNEQQLEPFELAVLEFLLNYHHHMDECDSEFFACFFTSSRKLSKSAIRLACLLLERQPRLAETFAELLPSN------LEQKDLVYPLLDIALTKNYQIPLPVLQRCYQTYKNGFMKSIEKPQKAALIYREHSEASALLIALCMPKSECFDYCQKQLKLDSVELFQVRVLREIYWQGFAAAKDEKQKATVFVNYINLNVQLLALDLKKQALDLPKLEQISWNCYEWWKTNRTDDLPLDWSRLQKNPQWLNFCKSSLKLALHLGEERLPLQDETNGLVLKLMAFLCDGMYDEYKEDAQQEEDATPTLLYEMICTHSCCFDHLLGKPSETKTHILHLMEVLARKAPSALQSDHIPVILGSYHAKLSPADRYGLALLEHYERFDVGLDKFRPFIWGESAVAHYALRAADEDVRTRLQQQETNVAQVLALIVRETSEYTIENFPIWRSLHASQQLPSTEFQNPAKKSMSFGDNQLEQMVEQGQLDFPQDLRRICPKRETIYETCYDPAFLLPLMMHCFAPESVVWARWPVQNGLLAITFCGLSSLDKDMRLAAASCQQRYRAHFELSNFYERPLWTQAYENIQAGLADLRNSWLAQRRTHGGTPRVPLIPGLFIAHSFNLSTEPTHLLYKRLMMYLRLKQSFNFQTIPDFNVFFYSQEPEHQQYREFIVELLRCGIKCSADLFLLVSTNTFKVLLGFYGSSLASLETNLLLLSVLSTCVKIPGAVKIMLEHVGILSWLVGVIRDTEFHQFDIIEGVISILNNLWYALAASRS--------------------ELTDYDHIQLRVYRLVLQLLPLLSPRISVPGLGRLFNVLWKTGSACGQHRAVS-----------------------------------ATQMDTLLECVSRQWPDQLASVRYVRSFGSAGACSRSEYCDWLAKDQKLETP--------------------------------------------------AVLALSSLREYVIDWAQAHKSESDGETKLLVEPTE--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34241-1", "uniprot_id": "URB1_YEAST", "id": "P34241-1", "name": "Nucleolar pre-ribosomal-associated protein 1", "aln": "---------------------------------MSNHSEAYGSRDQRREKYTQGKEFEDGTLETLESIISAVEDETLSKDYQPLIVFFQRGFGAQLVQTWSYYAQVNNHGKFS---------------------KTTSLLTKTLRV---------LSSDTSTVTIGSGLIRLILTDYTKVLYRGLNNMRAQLTN--------------------PILRLLKQIVNFNNGQHIEELVSYFDFSLPILPRLLVPSKSELANGNSSADSSK--------HDSLRFTFIKFWLTLISNASPFVRKELLTENFKIMSNLFKFMNKADSDKLSEHILSVFINDILKEKSFKRTTKTKILNELAASKIHHFYYSS---NKNLVKKANEFFLTFGASRDFSVAFPDNCVWFKNSVADGASHGAPITVNQVEFQIHN---KLLFNTLRLFKPWEDTLQLGTLIKILENVPELVAPYSIFLTTNGNYDPKMTSYWFGITLLINKIINLK---IPQFMEKVDSNIPPATSLVIENILPSLLTKSSLVKSLQFETPIIRQLACQSIVLALK-KLEKVSTFYDQKGWRNE-----------KTILLNEFHTRIPDLPIFVSTLSNSLASN--------------------------KDNRILPLSISIIFNYYSKMFPN-LFSINLPSSNIYTDIMQKSKISGIEFAILDNYLQFQEFNSTQTRWWNPSSGGNSLFTLLLKLASSKNASNVITTRISNLLDELTRTNVIFNISLISPVMALVNSLQGLSLQVSEIDNMEQ-----VWKWFDETISRVVKTPYKYVDMAKEYNYISPFIMCLSEQ-------------------------------WKYVDKSGNPEFLIKWLILFLRNMIFIG----------EDHIGIDKLVKNVFPEVSDHDVNIYLKLDSFEEN--------------------------------------------------------IKKTNSSNSLISSMKSSSFFQYISALPSKNLMNISRLPVNKLDAAG------------ILFRVQLLVEDDSVVYDNWFEATACELTGKIASYMVTDTEFPIIKVLERYINFALPKLAIEKRNALLMKK------------SRFMCNLIGAVCFETGHQLVEFREIIQKVVFSGENVEEYANYNELYQKEDVNAF--------------------LTSVSEYLSTSALTSLLMCSTKLESTRNILQKLFNE--GKTIKISLVKNILNKAANEDPASIKEVNISLAKFFEE-----NKVCVDASSDPMGKLSLSETTSLINSFVSSDLNYLVLKAFYRWEHFSFPSFIPS----------------------------IWRIKDSPLLSIVTTAALFKHMQDKDFSAFAHETISKYGNEIAKSTYTTSKSEIFDEILNMITTYIDFYDETKRNEILKCVLSQSDHKYHAATVRYIAAHNNFTYPGVETWLHKTLLYLTKYLSERKVISN--SFFELLRAMAELLKLEEVPNKLNVKIINSQLEAILGSEWIKQIKVLEYVIVLIFCVS------------------KKSIQSQRMVQLLLSNDSYSSIMIKDNDEDSSYRKFLSTMILFSLFSIDPVVNSTP-IVQEKLLTFYSGTISSNDKLILKILETIESHTATSWTNMIFSWEFIKDEEEEILEAIG----DTRLITKEREGLILTLQKNMIKKSIDRYVLERPQVPELYTDSNTNNYDATTRCDLVK------------------------------------------------KYYDDTERSGVDMYDPLFLLLLIIHNKELVKMVKDDEGNVTYRYEFENFLDCKIFQFIICSLSDCHTVAN-------------ISYEHLSNLASSLEKKTAQMNLEKQITSKDNERKESDSDLIKYNSIYQVLIKRILYQRQQNQDPINPLIWFSISR---------------IVDLLGSPTAPLHEKAYRWVLSN--STIRSWDIPMVSDVMMSYNKRQQDDNKKEIDMEIYYGELSWVLTTICKG-------------------------IKTDEDYKMLEKKGVFEWLLNLINMPYLKERLRELIYFIFYKVQRVADDGGLN------------------------------------LISRNGIVSFFEVLNNNIKSRLPQDDILNNIGTLRNENRGTLNTTLRLAQE------------------------------------------------------QNGIEKLLLGYNELVKSQKRLILWTEGDSDNVVKRLRK-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . . . : : . : . : .. . . : . :. ::. . : * .. . : . . . : : * :: : .*:: . * .* : . : : :* ::: * *::: .. ::* ::: :: * :*..: ::.: .: :* *. .: .:: :* . . . : . . .. . : : . .** : : * .. : . ::. * *:* . . * .: . : : : :. . . : . : : : : *. :: . : ::. : : : :* : .: .: :. : : :: .: . : . : .: : . . . : :: : : . .:. : . .:. . : :: . : : :.: :. : . . . . : :: : : ..: :. : : . : . : : : . * : *: : . . . : : . : .. . . : : : . * :: .: * : . : .. :. :: : : :: : : . . :: :: .: *. : : * . :. : . . : : : * :: .: : . .: *. : : : :..:: . . : . * . :: : . . : : : : . : : . . : . : . : . . : : . : * .. .: * . . . :: : . :* * ..:* *: * :*. * . : * . : . :: : : :* .: * . .: : . . : . * : :: . : * .* : : * : . : :. . : :: ::: :. : :: .* ::.: *. . : : . : :: . : :.. : : . :* : . . : * : : * .: :. . . :: . * .* .: : :. : .. ", "identical_positions": 55, "similar_positions": 419, "identity": "2.26%" }, { "cls_id": "homologset.agr.SGD:S000001499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31399-1", "uniprot_id": "ATP5H_RAT", "id": "P31399-1", "name": "ATP synthase peripheral stalk subunit d, mitochondrial", "aln": "---------------MAGRKLALKTIDWVSFVEIMPQN--QKAIGNALKSWNETFHTRLASLSEKPPAIDWAYYRANVDKP---GLVDDFKNKYNALKIPVP-------EDKYTALVDAEEKEDVKNCAQFVTGSQARVREYEKQLEKIKNMIPFDQMTIDDLNEVFPET--KLDKRKYP-YWPHQPIENL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCX2-1", "uniprot_id": "ATP5H_MOUSE", "id": "Q9DCX2-1", "name": "ATP synthase peripheral stalk subunit d, mitochondrial", "aln": "---------------MAGRKLALKTIDWVSFVEVMPQN--QKAIGNALKSWNETFHARLASLSEKPPAIDWAYYRANVAKP---GLVDDFEKKYNALKIPVP-------EDKYTALVDQEEKEDVKSCAEFVSGSQLRIQEYEKQLEKMRNIIPFDQMTIDDLNEIFPET--KLDKKKYP-YWPHQPIENL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75947-1", "uniprot_id": "ATP5H_HUMAN", "id": "O75947-1", "name": "ATP synthase peripheral stalk subunit d, mitochondrial", "aln": "---------------MAGRKLALKTIDWVAFAEIIPQN--QKAIASSLKSWNETLTSRLAALPENPPAIDWAYYKANVAKA---GLVDDFEKKFNALKVPVP-------EDKYTAQVDAEEKEDVKSCAEWVSLSKARIVEYEKEMEKMKNLIPFDQMTIEDLNEAFPET--KLDKKKYP-YWPHQPIENL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24251-1", "uniprot_id": "ATP5H_DROME", "id": "Q24251-1", "name": "ATP synthase subunit d, mitochondrial", "aln": "---------------MAARRIAQSSINWSALAERVPAN--QKSSFGAFKTKSDIYVRAVLANPECPPQIDWANYKKLVPVA---GLVDSFQKQYEALKVPYP-------QDKVSSQVDAEIKASQSEIDAYKKASEQRIQNYQKEIAHLKSLLPYDQMTMEDYRDAFPDS--ALDPLNKPTFWPHTPEEQVGYKSKEQLEAEAQGHH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAH1-1", "uniprot_id": "A1ZAH1_DROME", "id": "A1ZAH1-1", "name": "", "aln": "MWEKLVNCIKSNGGNGGVKNVSCQVVELADLMKQVPPN--QMHKFKMFAKKHEEYKDRVRKYPESMPTIDWEYYRQNVREEF-VDWVKGYETKYDKLHSVFENRHAIVDHKRYFELVDEEKKVVTKCISEYKAESDKRIQELTEKLEFVKAMRPYSEMTMEEFCFARPHL--APDFINKPTFWPHTPEEQMPGPSDPEAAAALHHEEEPEPPKKPAPEKLPDKPSGEGKPPAAAAPKEPKEPVVDTSQLAEKATLIAKDLMAKAIVLFNSLKEKMSGLAKNVQKKADAAKAARSETASKSATPTAAPTKSLDSITERESGPNICNQTIIRSEEAEANPEVKARHTNLSIEADPCDAQEERAREIARTLERKRQLKEAEEWEKHKTKKDPCDAEKETDPCKLMEEETVCKPDPCKAKEEEAVCKPDPCQQKEKEDDICKPDPCKPKDEEGSCEDEEDPCKKKPKCDGDYQFGGDNEGGSTKSKQQDQVFINISECSKELAKQEEKKSGDSGKPKEKASLSEIPQGSDQKPVLGMQITESKDSKKDHKASIEGANEIGPVYTDPNQLAELLVQKKEKPVIIEEAQKPEDDKPITIYPKLEISANPKGDQVKQEAEGQKSPKDMAKQVFTMASGAATLLTEATNTLEDLKRKKEARLEALEQAYTSAQRQAQGALAEASKAVEAANNLAIRSAEQTGEVSSRDREALEMAEKHAILAKMLAGRAVALKDEIARVLKDLKKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30902-1", "uniprot_id": "ATP7_YEAST", "id": "P30902-1", "name": "ATP synthase subunit d, mitochondrial", "aln": "---------------MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQLLELQSQPTEVDFSHYRSVLKNTSVIDKIESYVKQYKPVKIDAS---------KQLQVIESFEKHAMTNAKETESLVSKELKDLQSTLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWDVPGYKDRFGNLNVM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . :: . . : . : . : : . . :*: *: : . :..: .::. :: : :: * . . .: : . : :: *:.::*::: *. : * :: ", "identical_positions": 7, "similar_positions": 54, "identity": "0.95%" }, { "cls_id": "homologset.agr.SGD:S000001500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40694-1", "uniprot_id": "SMBP2_MOUSE", "id": "P40694-1", "name": "DNA-binding protein SMUBP-2", "aln": "MASSTVESFVAQQLQLLELERDAEVEERRSWQEHSSLRELQSRGVCLLKLQVSSQRTGLYGQRLVTFEP------------RKFGPAVVLP-----SNSFTSGDIVGLYDT-NENSQLATGVLTRITQKSVTVAFDESHDLQLN-LDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDILLGSSTPSPAMEIPP--LSFYNTTLDLSQKEAVSFALAQKELAIIHGPPGTGKTTTVVEIILQAVKQG--LKVLCCAPSNIAVDNLVERLALCKKR--ILRLGHPARLLESVQHHSLDAVLARSDNAQIVADIRRDIDQVFGKNKKTQDKREKGNFRSEIKLLRKELKEREEAAIVQSLTAADVVLATNTGASSDGPLKLLPED----YFDVVVVDECAQALEASCWIPLLKAP----KCILAGDHRQLPPTTVS--HRAALAGLSRSLMERLAEKHG-AGVVRMLTVQYRMHQAIMCWASEAMYHGQFTSHPSVAGHLLKDLPGVTDT-----EETRVPLLLIDTAGCGLLELEEEDSQS--KGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSN--KHPELEIKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVN--NHAFLETLVDYFTEHGEVRTAFEYLDDIVPENYTHEGSQGHSRVP-KPKCPSTSIRKPASDQESGQETRAAPRHGRRKPSEKPPGSHVQSQHSSSANGSDRTGGPDRTEHFRATIEEFVASKESQLEFPTSLSSHDRLRVHQLAEEFGLRHDSTGEGKARHITVSRRSPASSGSVAPQPSSP-PSPAQAEPEPRAEEPVTVVQAHCPVQLDLKALHLERLQRQQSSQAQTAKGQPGGDSRPQKASQKKKKKEPKGPVMALPCEEDFDALVSAVVKADNTCSFSKCSVSTTTLGQFCMHCSHRYYLSHHLPEIHGCGEKARAHARQRISREGVLYAGSGTKDRALDPAKRAQLQRRLDKKLGELSSQRTSRKKEKERGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQN5-1", "uniprot_id": "SMBP2_RAT", "id": "Q9EQN5-1", "name": "DNA-binding protein SMUBP-2", "aln": "MASYTVESFVAQQLQLLELERDAEVEERRSWQEHSSLKELQSRGVCLLKLQVSGQRTGLYGQRLVTFEP------------RKFGPAVVLP-----SNSFTSGDIVGLYDT-NESSQLATGVLTRITQKSVIVAFDESHDFQLN-LDRENTYRLLKLANDVTYKRLKKALLTLKKYHSGPASSLIDVLLGGSTPSPATEIPP--LTFYNTTLDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQG--LKVLCCAPSNIAVDNLVERLALCKKQ--ILRLGHPARLLESVQQHSLDAVLARSDNAQIVADIRRDIDQVFGKNKKTQDKREKSNFRNEIKLLRKELKEREEAAIVQSLSAADVVLATNTGASTDGPLKLLPED----YFDVVVVDECAQALEASCWIPLLKAP----KCILAGDHKQLPPTTVS--HKAALAGLSRSLMERLAEKHG-AAVVRMLAVQYRMHQAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVADT-----EETSVPLLLIDTAGCGLLELEEEDSQS--KGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSN--KHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVN--NHAFLKTLVDYFTEHGEVRTAFEYLDDIVPENYTHEGSRSHSCAP-KPKCPTTSVRKPASAQESRQEARAATGHSRRKPSEKPLGSQVQPQHSSKANGSDRTGGTDRTEHFRAMIEEFVASKEAQLEFPTSLSSHDRLRVHQLAEEFGLKHDSTGEGKARHITVSRRSPAGSGSATPQPPSP-PSPAQAEPEPQVEQPVG--QPHGSTQLDLKALHLERLQRQQGCQAQS---QLGGGSRPQKAPQKKKKKEPKGPAMALPSEEDFDALVSAVVKADNTCSFTKCSASTTTLGQFCMHCSRRYCLSHHLPEIHGCGEKARAHARQRISREGVLYAGSGTKDRALDPAKRAQLQRKLDKKLGELSSQRTSKKKEKERGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38935-1", "uniprot_id": "SMBP2_HUMAN", "id": "P38935-1", "name": "DNA-binding protein SMUBP-2", "aln": "MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLYGRLLVTFEP------------RRYGSAAALP-----SNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDESHDFQLS-LDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPASEIHP--LTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQG--LKVLCCAPSNIAVDNLVERLALCKQR--ILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPES----YFDVVVIDECAQALEASCWIPLLKAR----KCILAGDHKQLPPTTVS--HKAALAGLSLSLMERLAEEYG-ARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAAT-----EETGVPLLLVDTAGCGLFELEEEDEQS--KGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVH--RHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVN--NHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPAS-KEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGSLDPAKRAQLQRRLDKKLSELSNQRTSRRK--ERGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34243-1", "uniprot_id": "HCS1_YEAST", "id": "P34243-1", "name": "DNA polymerase alpha-associated DNA helicase A", "aln": "----MNKELASKFLSSIKHEREQDIQTTSRLLTTLSIQQLVQNGLAINNIHLENIRSGLIGKLYMELGPNLAVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVKKVSEDSNGEQAECSGVVYKMSDTQITIALEESQDVIATTFYSYSKLYILKTTNVVTYNRMESTMRKLSEISSPIQDKIIQYLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINFAIN-NDLTIIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDILSKKN---TIVKDISQEIDKLIQENKKLKNYKQRKENWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPENSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVR--YPNIDDYL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 216, "similar_positions": 239, "identity": "20.73%" }, { "cls_id": "homologset.agr.SGD:S000001501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UXN9-1", "uniprot_id": "WDR82_HUMAN", "id": "Q6UXN9-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BFQ4-1", "uniprot_id": "WDR82_MOUSE", "id": "Q8BFQ4-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R565-1", "uniprot_id": "M0R565_RAT", "id": "M0R565-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMKWWLPCYPVS-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NV31-1", "uniprot_id": "WDR82_DANRE", "id": "Q6NV31-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSSNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHNKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKLQYERTCEWTGLKFSNDGKLILVSTNGGTLRVLDAFKGAVLHSFGG----YNNSKGVILEASFTPDSQFIMIGSEDGKIHVWNAESGMKVALLDGK-------HTGPVTCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLN1-1", "uniprot_id": "WDR82_DROME", "id": "Q9VLN1-1", "name": "WD repeat-containing protein 82", "aln": "-MKIKLIDSVVRSFKVAKIFRENTD---KINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISP-VEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAG-VNSESIKLYDLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTG----YPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGD-------HPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEGL------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQD1-1", "uniprot_id": "Q9VQD1_DROME", "id": "Q9VQD1-1", "name": "WD repeat-containing protein 82", "aln": "-MSIRLNDDAMRQFRVAKVFPETKH---HTLAMEFSSDGLRLLVCDHS-ALSIFSSTRQVQVCKVPMHHYLPDVACFVQQDTRVLHSTSKHDYTIRCLDLNTRHCVRVFGGHAKTINRLASQPGGENVFISAGRDDQVYMWDIRVKTHTHRIKNLRRPLCAFDPEGLFLATS-SGTEGIQIRDVRMMGGEPSRKFVYQVNAKANWTQLQFAPNGKSLLLSTDHSWCFSVSAIDGTYQQSFTG----YSNKLRLPLDATYTPDSQFILSGADKGRIHIWRAADGFPVAVLKGN-------NMGPVRCMRFNPRATMFVSSDSRIVFWMPMANGVYDWVKRLKPGETISFTDETVQEEAVKAPRTIPMPKPKIETVWKIKRLNRKRACTGDEIVDLTNALHNNDSMEDGEIAED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36104-1", "uniprot_id": "SWD2_YEAST", "id": "P36104-1", "name": "COMPASS component SWD2", "aln": "MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLTSSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLETNQYLRYFSGHGALVNDLKMNP-VNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIAYDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLVGSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAIWNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .*: .* * . .::* :* :: .. . : ::.. . .: ::* . :.: . ::*:. : *: *.*. .: :* * ** : * .* ::.*:*.. *. : :**:: . : ::**.**.:* . . : : ::: : * : : .:*. *:*: :** :*:.:. . ..*: * : * .. .* ::**.:*:: .*:: :*. . :* . : .: ***: :.:: : ::: ", "identical_positions": 46, "similar_positions": 118, "identity": "11.17%" }, { "cls_id": "homologset.agr.SGD:S000001502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04631-1", "uniprot_id": "FNTA_RAT", "id": "Q04631-1", "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "aln": "MAATEGVGESAPGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQN-DGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD-------LQEEMNYIIAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILN--QDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQ--DRG---LSRYPNLLN-QLLDL-QPSHSSPYLIAFLVDIY-EDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSRESDIPASV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61239-1", "uniprot_id": "FNTA_MOUSE", "id": "Q61239-1", "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "aln": "MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQN-DGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD-------LQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILS--QDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQ--DRG---LSRYPNLLN-QLLDL-QPSHSSPYLIAFLVDVY-EDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49354-1", "uniprot_id": "FNTA_HUMAN", "id": "P49354-1", "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "aln": "MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVLYRDRAEWADIDPVPQN-DGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKD-------LHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILN--QDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQ--DRG---LSKYPNLLN-QLLDL-QPSHSSPYLIAFLVDIY-EDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR31-1", "uniprot_id": "Q9VR31_DROME", "id": "Q9VR31-1", "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "aln": "------MGDSS----------------------------------------DEEYLGTD---WLAYSERSDWEDVQPLAQD-DGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRALDLTTDALRLNPANYTVWQYRRDVLRELKAD-------LYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLNDPSNELELTENALVNDGDAKNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVIK-HFGFTP-ELIQRELSYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVD-FVEELYQAGNRSPYLLAFLIDLYQEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVANHLKNQLSTVEQK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29703-1", "uniprot_id": "FNTA_YEAST", "id": "P29703-1", "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "aln": "------------------------------------------------------------------MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISLNELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTLNNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDFQHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNISPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLAYHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: *:.*:. : * . : * *::.:: : . **:: .* * **:.** : : : .* **:*::* ::: : : * *:::: : ::.****:* :*: ::: .** : *: * *:****.*.:*:* * ::.** :.. *:. * ***.*.:* * . : *:.: :: *::: :* *.*.** *. . . * :. : :: . ** :. : . * : * : . . :. . :* : * **:: *:: . *: ", "identical_positions": 68, "similar_positions": 109, "identity": "17.13%" }, { "cls_id": "homologset.agr.SGD:S000001504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VXW4-1", "uniprot_id": "Q9VXW4_DROME", "id": "Q9VXW4-1", "name": "CG9123", "aln": "-------MPPEMEIIEATNEELLLGFKLIKSPTDGFTDSVKFELKQTFADSSYARSITSLAVQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLS---------------LLLSGSDDGHMIATRVGSWTKEYDWQKAHAGQAVTHVSCHPSSKLALSLGGDQVLNTWNLVNGCVAHKTNLKNKATLDFQTGCLSWS-KQGDHFTLSGPLVLEIWGIENAHVMRRIEMPSK------PICITWLDGNECLTGLDNGNIAWISLKDEDDTPPTFILAHEVRVKAIAYLN----EFLATVSIAGQIKVWKIDMETRKLEEIARSFMDCRPTDLGLLDLRQFGNVRPVEQRTKVEEKPKAKVESDQSAKPAAPRGFVTIEYEQDKKLDAEKKKEK-KKN--------KKDEESSEESNSSEDKENDDFSDSDSDVSSDHGHRKRKPMKREQQPTPASKGKAKQQKKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXW3-1", "uniprot_id": "Q9VXW3_DROME", "id": "Q9VXW3-1", "name": "P21-activated protein kinase-interacting protein 1-like", "aln": "-------MPPEMEIIVGTYEEVLLGFKLIKSPTDGLTDSVKFELKQTFADSSHAGSITSVAVQWPWVASGGTDDRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLS---------------HLLSGSDDGHMIATRVGSWTKEGDWQKAHAGQAVTHISCHPSSKLALSLGGDQVLNTWNLVNGRVAYKTNLKNKATLGLQPGCLSWS-KQGDHFTLSGPLVLEIWGIENAHVMRRIEMPAK------PICITWLDGNECLTGLDNGNIAWISLKDEDDTPPTFILAHEARVKAIAYLN----ELLATVSSAGEIKVWKIDMETRKLEEIASSFMDCRPTDLGLLDLRQFGNVQPVEQRIKVEEKPKAKVESDQSAKPAAPRGFVTIEYEQDKNLDAEKKKGKGKKNKIQAKKAQQKAEESSEESNSSEEKESDDFSDSDSDVSSDHGHRKRKPMKRKQQPTPASKGKAKQQKKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DCE5-1", "uniprot_id": "PK1IP_MOUSE", "id": "Q9DCE5-1", "name": "p21-activated protein kinase-interacting protein 1", "aln": "-----------MELVAGSYEQVLFGFTVQRGPAK-SGHQETWTPVADFTHHSHTASLSVLASNSRYVVSGSKDETIHIYDMKRKVEHGALVHHAGTVTCLKFHGNQ----------------HLISGAEDGHICIWDVKRWKCLKTFKAHRG--HVTFLSIHPSGKLALSVGTDKTLRTWNLIEGRSAFIKNIKENAHI------VEWS-PSGGKYIVVVQNKVDVYRLGTASVSGTITNGKR------ISSVTFLSDSVLAVAGDEEVVRIFDCDS--LECLCEFRAHENRVKDMVSFEVPDHHVLVTASNDGFIKMWTLPQDK----KVPPSLLCEAKTGARLTCLTVW-------------------LDRAANGMASLPPAAEPCP---DQPKTIEKESGD---------------TVQEET--SEPNSEKSDVSGDSKQPTKGNSP---VTAKKRKMATMSEKKRKKKM------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWT1-1", "uniprot_id": "PK1IP_HUMAN", "id": "Q9NWT1-1", "name": "p21-activated protein kinase-interacting protein 1", "aln": "-----------MELVAGCYEQVLFGFAVHPEPEA-CGDHEQWTLVADFTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNR----------------HLISGAEDGLICIWDAKKWECLKSIKAHKG--QVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHI------VEWS-PRGEQYVVIIQNKIDIYQLDTASISGTITNEKR------ISSVKFLSESVLAVAGDEEVIRFFDCDS--LVCLCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDK----KVPPSLLCEINTNARLTCLGVW-------------------LDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGD---------------TVHKEEKRSKPNTKKRGLTGDSKKATKESGL---ISTKKRKMVEMLEKKRKKKKIKTMQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TNS2-1", "uniprot_id": "PK1IP_DANRE", "id": "Q6TNS2-1", "name": "p21-activated protein kinase-interacting protein 1-like", "aln": "MSECFTVMGDHIELVAGCYEQIVFGYRVCP-------ADEEWTIEPTFTHHAHTASLNAVSSSNQFIATGSKDETIQLYDMCKKTEHGALLHHDGTISCLEFYGTS----------------HLLSGGQDGLICVWSTKKWECLKTIRAHKG--QVTSLSVHPSGKLALSVGTDKTLRTWNLIEGRSAFIKNIKQNAEI------VLWS-PDGDKYAVVVNDKVDIYTLDSATIIGTIAFTKR------ISCLKFLKNSLLAVGGDDESVRIYDVTS--QKCVCEFKAHENRVKAIESFMKDDFCVLVTASNDGFIKLWKLNLES----IESPTLLGQLNTTARLTCLCVW-------------------MPGETKETAEQP----------AQATTSEDVLDP---------------LVPVRS-------KRVRILGEEVIMEDEKGS---KTQGKK-------KKRQKVQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20484-1", "uniprot_id": "MAK11_YEAST", "id": "P20484-1", "name": "Protein MAK11", "aln": "--MSAIGDKNQFRIIVGSYEHNILCLSLDIPNQKENDAAKTPHFMPIFHFQAHSLSIKCLAVSRRYLVSGSNDEHIRIYDLQKRKELGTLLSHQGSITALQFSHPASSSEDAAVSKGSKNSKWLLSASEDHKIMVWRVKDWETVGTLKGHTA--RVNDVDIHPTNRIAISVSDDHSIRLWNLMTLRNAAVLKLRKYNTNG---TCVRWLGAKGDYFAVGLRDRVLIYETGSAKVFKEIVFQRKTLMHIETHILPFDNKEYLSVGISDGNVHFYPCEELFEKVEENEKQEDDDDKEDISPA------FSLLGHTNRIKDFKFYTNEFG------TYLVTIGSDGKIVVWDMS--------------------TKEQVAVYDCGERLNCLTLCDESIEKYNTMKKR--------------------------DAETADIGDQSEVESDTEELKKIMFGEKKKLNKKKRKQLKKSKVSVELE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q924P2-1", "uniprot_id": "TM14C_RAT", "id": "Q924P2-1", "name": "Transmembrane protein 14C", "aln": "------------------------------------MQKDSGPLVPLHYYGFGYAALVATGGIIGYAKAGS----------VPSLAAGLFFGGLAGLGAYQLSQDPR-------------------------------NVWVFLATSGTLAG---IMGMRFYNSGKFMPAG----------LIAG------------------------------------ASLLMVAPGVAKIQEITTMP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : :*. :. . : :: * . : : : :.:: : *: : : * : ", "identical_positions": 4, "similar_positions": 26, "identity": "0.84%" }, { "cls_id": "homologset.agr.SGD:S000001505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FE70-1", "uniprot_id": "F7FE70_RAT", "id": "F7FE70-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLEPLRKRVRQYLDQQQYQSALFWADKVASLSHEEPQDVYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEYQQALDILD--MEEPINRRLFEKYLKDDSG----SKDPSSDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLDSLPLSKLCAEEQ-ELLRFVFENKLKKYNK---------------------------------PSETVIP-----------------------------------------------------------------------QSVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSAVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIG---NEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYI--DIKDKLKCYDFDVHTMKTLKNIISPPWDFRDFEVEKQNTEEAGLAPLENATKTPESRPSLEET-FEIEMNESDMMLETSMSDHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R349-1", "uniprot_id": "CDC16_MOUSE", "id": "Q8R349-1", "name": "Cell division cycle protein 16 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLEPLRKRVRQYLDQQQYQSALFWADKVASLSHEEPQDVYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDILD--MEEPINRRLFEKYLKDDNG----SRDPSSDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLDSLPLNKLCAEEQ-ELLRFVFENKLKKYNK---------------------------------PSETVIP-----------------------------------------------------------------------ESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIG---NEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYIGADIKDKLKCYDFDVHTMKTLKNIISPPWDFRDFEVEKQNTEEAGLAPLQNSTKAPESRPNLEET-FEIEMNESDMMLETSMSDHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13042-1", "uniprot_id": "CDC16_HUMAN", "id": "Q13042-1", "name": "Cell division cycle protein 16 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLD--MEEPINKRLFEKYLKDESG----FKDPSSDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLSKLCNEEQ-ELLRFLFENKLKKYNK---------------------------------PSETVIP-----------------------------------------------------------------------ESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIG---NEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYIGADIKDKLKCYDFDVHTMKTLKNIISPPWDFREFEVEKQTAEETGLTPLETSRKTPDSRPSLEET-FEIEMNESDMMLETSMSDHST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N844-1", "uniprot_id": "A0A8M1N844_DANRE", "id": "A0A8M1N844-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLDRLRKRVRHYIDQQQYQSALFWADKIASLSHEDPQDIYWLAQCLYLTAQYHRASHALRSRKLDKLYGACQYLAARCHYAAKEYQQALDILD--MEEAASKKLLDKNLKEENG----SREIVKDWEMSPASINSSICLLRGKIYDAMDNRPLATSSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKDFLDSLPLSQQCTEEEVELLHFLFENKLKKYNK---------------------------------PSEMVVP-----------------------------------------------------------------------DIVNGLQDNLDVVVSLAERHYYNCDFKMCYSLTSMVMVKDPFHANCLPVHIGTLVELSKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLERTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNPKLAEHFFSQALSIAPEDPFVIHEVAVVAFQNGDYKTSEKLFLDAMEKIKAIG---NEVTVDKWEPLLNNLGHVCRKLKKYEQALEYHRQALVLIPQNASTYSAIGYVHSLKGDFESAIDYFHTALGLKRDDTFSVTMLGHCIEMYISDSDAYIGTDIKDKVRKTLNTPALMKMLNTSAD------GNESRAQPVEEVNVCIETPSFNADKQTDAFQRFLLECDMHESDMMLETSMSDTST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCN6-1", "uniprot_id": "Q9VCN6_DROME", "id": "Q9VCN6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGDTENTSTDTTNEHIDLALYRQLVKQFIDMRRYSTALFWAEKVAVLGGLEPRDIYYQAQCMYLLGEYHRAAHTIQHHKLEKNSLPCFNLLLESLYAAKEFTEAANVIQNVEVEVMTTSLINQPVDASSGCYLESNSVFGGEENHRNELLSSIYLMKGKVYEALDNRGMAMDFYVQALHKSIYCFEALEALVQHEMLMAWEEFELMHHLPLAQQSSEADAKFILKLYESRLKKYYELISARNAEEMSPIVNPDILQFIKEFTARVQQSGSSDTQMPKVSAVKVPLTPSQFMSPAQKVLEDLKAPTFSLQTSLSKASSLIDASHRSMFDSSSRRRSRDHDTDTLIPIAECLDRVQRSTDLMAAEAEKCFYDCDYKQCLKILNELLKVDPFHNTALTIQIACLVENGDFNRLFYVAHKLVDRYPDKAISWYAVGCYYDMIG-KSDPARRYLSKATALDRLYGPAWLAYGHSFANENEHEQAMAAYFKATQLMRGCHLPLLYIGVECGLTKNLELAEKFFLQAMNIAPLDVYVLHELGVIKYEYEFFDGAATIFQCTVDIVKQRAKSNNEEISSRWEPLFINLGHSLRKVHKYEEALYNFQYALLLKPQSPTTYTSIGFIHALLGNLDPAIEAFHKSLALNRDCIVTSTILKSCIEDLMDDS-----ATIDEICSAALRDVAKNITAN-----------------------SRRVLNSDKFNGMKLKFDEE-EEFANSDSNMVVEMSFDT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09798-1", "uniprot_id": "CDC16_YEAST", "id": "P09798-1", "name": "Anaphase-promoting complex subunit CDC16", "aln": "MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMSPSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLANSPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRKVSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTTATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISN-DPDDAFWLGQVYYNNNQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAANTMSNNG---NNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKNFEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKE--IMKNLYKINLSKYIN---------------------------------TEDITKSN-------------------------------------------------------------------EILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLYELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLD-RISEAQKYYSKSSILDPSFAAAWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVLAYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLD-----PSSRTTISIQLNLGHTYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPNNSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSS------LTYDPVNMAKRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : : * :* : *:*: :. :* * :: .* * :* ** . : .:*: * * . :.. :* ::: ..* . .: **: :::**:* * :* * : :*: .: ***:: * .:.:* . ** :::. * : : : : :: ::: .*.** : ..: . : . *:: : .: : :*.:: * .: . :: * *: . *. *. * * .. *.** ::*:*.: :*...::*::*. ** :. : . *::* **:: *: :..**:.:.*::* *.*::**::** .*:::: * *** *::*:: :. :*** :* * .*.* * *::*:.*: :: : : . : ::: :* .: **** **::: *: .: .* :.. : ::*::: .:: *:: :*.:* *. : : ::* .:* : * *.. : : . :.:: : .:. ", "identical_positions": 107, "similar_positions": 209, "identity": "11.12%" }, { "cls_id": "homologset.agr.SGD:S000001507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30085-1", "uniprot_id": "KCY_HUMAN", "id": "P30085-1", "name": "UMP-CMP kinase", "aln": "----------MKP---LVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBP5-1", "uniprot_id": "KCY_MOUSE", "id": "Q9DBP5-1", "name": "UMP-CMP kinase", "aln": "----------MKP---LVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEVFGEVVKIFDKEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM73-1", "uniprot_id": "KCY_RAT", "id": "Q4KM73-1", "name": "UMP-CMP kinase", "aln": "----------MKP---LVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIDRCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEVFGDVMKIFDKEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZWE9-1", "uniprot_id": "KCY_DANRE", "id": "Q7ZWE9-1", "name": "UMP-CMP kinase", "aln": "----------MKP---QVVFVLGGPGAGKGTQCARIVENYSYTHLSAGDLLREERSRTDSEFGQLIDSYIKEGKIVPVQITINLLRKAMEETMKADEKKFRFLIDGFPRNQDNLQGWNTEMDGKADVKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILEKDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15700-1", "uniprot_id": "KCY_YEAST", "id": "P15700-1", "name": "Uridylate kinase", "aln": "MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKAN--KHKFLIDGFPRKMDQAISFERDI---VESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *:************** ::*:.*.:.*****:*** *: ...*::*:**.. ****:*** :**: **:. :.:.: *: * :********: *: .:: : .: .*:***** ::: ::* *****:***:*** **::**::*: ::: *:*: :* .** :: ..:**::*: :* . : .. ", "identical_positions": 85, "similar_positions": 74, "identity": "40.67%" }, { "cls_id": "homologset.agr.SGD:S000001508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q640Q5-5", "uniprot_id": "PAN3_MOUSE", "id": "Q640Q5-5", "name": "PAN2-PAN3 deadenylation complex subunit Pan3", "aln": "MNSGGGGGLPPPSAAASPSSSSLAAAVAVAVAASSGVGGVPGGPAAAAGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLALAAAAGAAFPPGALPGGGAGPPAGPKKPELGVPGAATAGGG------LDGPRVAIPGMDGGALTDASLTESYFSTSFIGVNGFGSPVETKYPLMQRMTSSSSSPSLLNDSAKPYTGHDLLTSSASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSQARKAKNPLGCLADRCESGVPVSMVWWDRVPENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPH-TSPAPRRRSHTPNPASFMVPPSASTPANNPAPQPPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAP-SFFMADELRQELINRHLITMAQIDQADMP--AVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFR--LVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAGGETMMSRHFN---DPN--SDAYFTKRKWGQHDGPLPRQHAG-LLPESLIWAYIVQLSSALRTIHTAGLACR-VMDPTKILITSKT-RLRVNCVGVFDVLTFDN--SQNNNPLALMAQYQQADLISLGKVVLALACNSLAG--------IQRENLQKAMELVTINYSSDLKNLILYLLTD-QNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLISRDEKSVLVVTYSDLKRCFENTFQELIAAANGQL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L940-1", "uniprot_id": "A0ABK0L940_RAT", "id": "A0ABK0L940-1", "name": "PAN2-PAN3 deadenylation complex subunit PAN3", "aln": "MNSGGG--LPPPSAAASPSSSSLAAAVAVAVAASSGVGGVPGGP--AAGVKLKYCRYYAKDKTCFYGEECQFLHEDPASGAAPGLGLHSNSVPLALAAASGAGFPPGALPGGGAGPPAGPKKPELGVPGAATAGGG------LDGPRVAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTSSSSSPSLLNDSAKPYTGHDPLTSSASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPINMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPH-TSPAPRRRSHTPNPASFMVPPSASTPANNPVPQTPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAP-SFFMADELRQELINRHLITMAQIDQADLP--AVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFR--LVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFSEPSLVFAYDFHAGGETMMSRHFN---DPN--SDAYFTKRKWGQHDGPLPRQHAG-LLPESLIWAYIVQLSSALRTIHTAGLACR-VMDPTKILITSKT-RLRVNCVGVFDVLTFDN--SQNNNPLALMAQYQQADLISLGKVVLALACNSLAG--------IQRENLQKAMELVTINYSSDLKNLILYLLTD-QNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLTSRDEKSVLVVTYSDLKRCFENTFQELIAAANGNDRSSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58A45-1", "uniprot_id": "PAN3_HUMAN", "id": "Q58A45-1", "name": "PAN2-PAN3 deadenylation complex subunit PAN3", "aln": "MNSGGG--LPPPSAAASPSSSSLAAAVAVVAPP--GVGGVPGGA--AVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLALAGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPINMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPH-TSPAPRRRSHTPNPASYMVPSSASTSVNNPVSQTPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAP-SFFMADELRQELINRHLITMAQIDQADMP--AVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFR--LVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAGGETMMSRHFN---DPN--ADAYFTKRKWGQHEGPLPRQHAG-LLPESLIWAYIVQLSSALRTIHTAGLACR-VMDPTKILITGKT-RLRVNCVGVFDVLTFDN--SQNNNPLALMAQYQQADLISLGKVVLALACNSLAG--------IQRENLQKAMELVTINYSSDLKNLILYLLTD-QNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLISRDEKSVLVVTYSDLKRCFENTFQELIAAANGQL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95RR8-1", "uniprot_id": "PAN3_DROME", "id": "Q95RR8-1", "name": "PAN2-PAN3 deadenylation complex subunit PAN3", "aln": "MCSTYG--------LLSFEFSDTAAMDPIFFSP---TNGIPSES--------KLATYMNR----------QNVATPSGYGLNNGFSLLNLDSPLNKKSQVTPQSPE--FIPTRLGSTPNFYAPYHNAPMQLSNGLNG-----VNGLTAAAAAAAAAAAAAAAAVPSSTS------------------------SASSASVTISKTANGGASMLALQKTAS-----IASVTIAQQQPQHPQKQ---QQHPPSVGGGAVSAAS-----APIAISGAP----------------PNPAAAPFVS--------SMSAQTPLKGRGAMMRQESPTAAMISGAGPGE-----KSPPHG--MTPHGASPIPSALPTSVHQENVGGTIYFYPTANAQNSQPVVNSMVVDGTHPALHGVSAVAPMSAGVPAAMMYTGHVYPGPSSNVVTMQPKTLLESAFFMPDEMRAEVLARNEISNLIMDAAEAAQHALPLEVENYHALYPLEPPAQP----LHAKLTFPATTYRATHNTTGYKYCLRRIHGFR--LQSTKCMTLVEMWKKLQHTNVVQLREVFTTKAFGDNSLVLVYDYHPGSQTLLAKYFTPAPETNGYTDPFQGEARPFSHKSNMQRTSNGPLLPEATIWSIIMQLTAGLKAIHHAGLACK-VLDPTKIIVTGK--RVRFSSCCISDITQFDP--NASN-PLALVNMHQQDDLTALGRLVLALACRCLQS--------VQRDNVQSSIDMVTRNYSTDLRNFIVYLFTT-NNR-RSVTDLMPMIGARFYTQLDALQSKIDMQEDELAKEMENGRLYRILVKLNSINERPDFNLDCTWSETGDRYMLKLFRDYLFHSVTEDGRPWLDHAHIVQCLNKLDAGSIERVQLMSRDEQSVLIVSYAELKNCLENAFSELMSSAAN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36102-1", "uniprot_id": "PAN3_YEAST", "id": "P36102-1", "name": "PAN2-PAN3 deadenylation complex subunit PAN3", "aln": "------------MDKINPDWAKDIPCRNITIYG--------------------YCKKEKEG--------CPFKHSDNTTATT----INDVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTS-----------AATNATGNIAMAATSATASTVN---------------------PMINPIVNSSLVNNNNNNSNISISIPTTAS---------------------------------------------------------------------------------------------SSNYDPFNAPIFTPSSTSSIHT-------------------------NANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKYPRIYPPPHS-LLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQVFPSSGKV---IPSIVQDYFNLVPLN--------FNNNDFLNKTTLFKVFSNYDGKAYVLKRLPNIDKSMNPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVN---------------------------FPKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMDLLFNDDTDTVVSSGGSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEITPQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYMESVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNGKPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQ----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . : . . . : . *: . . ... . : . * . * : :: . * . .. . :... : : ..** .: . . : * :. : .. . . . . . . . :: .. . : : .:. ::*: :*:.:::* :: :: : : :* *:.*. * **: .: :: ::. . . * *:*: .: : .* : ::*.*:: :*:: :*::* *. *.: *: :.:*::... :: :* :.: :* ::**: :.:** .*: .:: *:::*.. *::.. . *: * . . : : ** * **.::: *: . . : ::: : . .:::.: **:: : :*: *: . : ::: *:: * : *. *::*::****:*:: **. * * : . * .***:* :: : ** *::**.* . * * :* :*:: ******** *:: * : ** . ::::* :** :*.:* .: ", "identical_positions": 97, "similar_positions": 227, "identity": "10.52%" }, { "cls_id": "homologset.agr.SGD:S000001509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PAF3-1", "uniprot_id": "A0A8M1PAF3_DANRE", "id": "A0A8M1PAF3-1", "name": "Glutathione peroxidase", "aln": "-----------MQKMGFIHRFLLFGALS-SSG------------------IIGATSAQL----------------------EDWQTAKSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRILAFPSNQFGRQEPGTN-SQIKEFAKSYNAEF-DMFSKIDVNGDGAHPLWKWLKDQPNGKGFLGNGIKWNFTKFLINREGQVVKRYSPLQDPSVVEKDLSKYL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N743-1", "uniprot_id": "A0A8M1N743_DANRE", "id": "A0A8M1N743-1", "name": "Glutathione peroxidase", "aln": "--------------MWLFQRALLVGAVG-SKS------------------FARAMCAQA----------------------NDWQSAKSIYEFSAIDIDGNDVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHVTYAEKGLRILGFPCNQFGKQEPGSE-AEIKEFAKGYNAEF-DLFSKIDVNGDAAHPLWKWMKEQPKGRGTLGNNIKWNFTKFLIDREGQVVKRYGPMDDPSVVEKDLPKYL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70325-1", "uniprot_id": "GPX4_MOUSE", "id": "O70325-1", "name": "Phospholipid hydroperoxide glutathione peroxidase GPX4", "aln": "--------MSWGRLSRLLKPALLCGALA-APG------------------LAGTMCASR----------------------DDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSN-QEIKEFAAGYNVKF-DMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36970-1", "uniprot_id": "GPX4_RAT", "id": "P36970-1", "name": "Phospholipid hydroperoxide glutathione peroxidase", "aln": "--------MSWGRLSRLLKPALLCGALA-VPG------------------LAGTMCASR----------------------DDWRCARSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSN-QEIKEFAAGYNVRF-DMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36969-1", "uniprot_id": "GPX4_HUMAN", "id": "P36969-1", "name": "Phospholipid hydroperoxide glutathione peroxidase GPX4", "aln": "--------MSLGRLCRLLKPALLCGALA-APG------------------LAGTMCASR----------------------DDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSN-EEIKEFAAGYNVKF-DMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRD3-1", "uniprot_id": "Q8IRD3_DROME", "id": "Q8IRD3-1", "name": "Glutathione peroxidase", "aln": "--------MSLRQFQNISRQALRCYSMRRTPGPVLELSRGQRQCLRLCTIMLPVSCAATPMNAISSAAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTG--TLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36014-1", "uniprot_id": "GPX1_YEAST", "id": "P36014-1", "name": "Glutathione peroxidase-like peroxiredoxin 1", "aln": "--------------------------------------------------------------------------------------MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTP-QYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKD-KEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIK-MIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9D7B7-1", "uniprot_id": "GPX8_MOUSE", "id": "Q9D7B7-1", "name": "Protein peroxidase GPX8", "aln": "MEPFAAYPLKCSGPKAKIFAVLLSMVLCTVML-----------------FLLQLKFLKP--------------------------RTNSFYSFEVKDAKGRTVSLEKFKGKASLVVNVASDCRFTDKSYQTLRELHKEFGPYHFNVLAFPCNQFGESEPKSS-KEVESFARQNYGVTFPIFHKIKILGPEAEPAFRFIVD------SSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99LJ6-1", "uniprot_id": "GPX7_MOUSE", "id": "Q99LJ6-1", "name": "Protein peroxidase GPX7", "aln": "----------------------MVAAVATAWL-----------------LLWAAACAQS--------------------------EQD-FYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQNYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDTN-REIENFARRTYSVSFPMFSKIAVTGTGAHPAFKYLTQ------TSGKEPTWNFWKYLVDPDGKVVGAWDPTVPVAEIKPRITEQVMKLILRKREDL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* : *. . ::. :. . ::.*:**. * .* : : : :: **..*** . . : . : *: * * :::: *** *:::: :* : : : : . ", "identical_positions": 20, "similar_positions": 45, "identity": "7.72%" }, { "cls_id": "homologset.agr.SGD:S000001511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V992-1", "uniprot_id": "G3V992_RAT", "id": "G3V992-1", "name": "General transcription factor IIE subunit 1", "aln": "--------------MADPDVLTEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTFTDLEANQLFEPMTGTFRCTFCQAEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQ---------------SKDRAASAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVISMDD---QDDVHRTSLEGKAAKERPIWLRESTVQGAY--------GSEEMKEGGIDMDTFQDREEAR-AGPDDNEEVMRALLIHEKKTSSATAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAAAP---------HHRDEDEE-DDEFEEVADDP---------------VVMVAGCPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0D5-1", "uniprot_id": "T2EA_MOUSE", "id": "Q9D0D5-1", "name": "General transcription factor IIE subunit 1", "aln": "--------------MADPDVLTEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQ---------------SKDRAATAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVINMDD---QDDVHRPSLEGKAAKERPIWLRESTVQGAY--------SSEEMKEGGIDVDTFQEREEAR-AGPDDNEEVMRALLIHEKKTSSVTAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAAAPP-------HHHRDEDEE-DEEFEEVADDP---------------IVMVAGCPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29083-1", "uniprot_id": "T2EA_HUMAN", "id": "P29083-1", "name": "General transcription factor IIE subunit 1", "aln": "--------------MADPDVLTEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQ---------------SKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDD---QEDLHRASLEGKSAKERPIWLRESTVQGAY--------GSEDMKEGGIDMDAFQEREEGH-AGPDDNEEVMRALLIHEKKTSSAMAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAVAV---------HKREEDEEEDDEFEEVADDP---------------IVMVAGRPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SQE1-1", "uniprot_id": "Q5SQE1_DANRE", "id": "Q5SQE1-1", "name": "General transcription factor IIE subunit 1", "aln": "--------------MTEPELLTEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQIEPIYVLLRETENINLSHDLLEPEPSEIPALKQ---------------SRERAAQTAAGAG-AGGPVREVWK-KGTSYD-LYTQNVVINMED---QEPQPGQNAEGKAPKERPVWLTESTVQGAYN-------ETEALKNPGEDSVVTQEGITGRGAAQDENEEVMLALLIHEKRSGAGPGGSAVSRPTVPAANASDSDSDTSESDEDSPPQAPAHTLHSTTSMRPGKQDEEDEDDDDEFEEVGDDP---------------VVMVGGRPFSYREVSQRPELVEQMSAQEKEAYIEMGQNLFQDMYF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96880-1", "uniprot_id": "O96880_DROME", "id": "O96880-1", "name": "General transcription factor IIE subunit 1", "aln": "MSSTSTAAANAAPAKTEVRYVTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTLRTDKFIQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSSCSKTFTDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQPLYDLLREVEGIKLAPEVLEPEPVDIDTIRG---------------LNKPNATRPDGMAWSG----EATRNQGFAVEETRVD-VTIGGDD---TSD---AVIERKS---RPIWMTESTVITDT-----------DAADGAADAVQTASGSGHR--NRKENEDIMSVLLQHEKQPGQKEPHMKGMRVGSSNANSSDSSDDEKDIENSKIP----------------DVDFDNYINSDSAEEDDDVP---------------TVLVAGRPHPLDQLDDN--LIAQMTPQEKENYIHVYQQHYSHIFE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36100-1", "uniprot_id": "T2EA_YEAST", "id": "P36100-1", "name": "Transcription initiation factor IIE subunit alpha", "aln": "-------------------MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVHQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYTYNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQRELQERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTASAMDSINPDNEPAQETSYQNNRTLTEQEMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEEEEEMEDVMDD-----NDETARENALEDEFEDVTDTAGTAKTESNTSNDVKQESINDKTEDAVNATATASGPSANAKPNDGDDDDDDDDDEMDIEFEDV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.* : *:****. . .* :* :: :. : *:*: :** :::.:* . : *: *:::. : : * .:.*: . **:::* ::.:*:*:. : :*:: : . :. .: *. * ..:*:*** **:: * *::* : **.:. :*: : : :: :*::*: *:: :. .: : :* : . : . . : * : :. :: . * : * * :**: . . : .:*. : : ..:. . * .:...: .: ::.. . : .:. *: * . : . : ..:: : : . : ", "identical_positions": 52, "similar_positions": 145, "identity": "10.28%" }, { "cls_id": "homologset.agr.SGD:S000001512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VG31-1", "uniprot_id": "Q9VG31_DROME", "id": "Q9VG31-1", "name": "Malic enzyme", "aln": "MGNSSSICADRNVITNFDENGTPVYPTANNSQSPSSYSRGKERELGCYTKRNSNSNNNNSHERESQSCCSSRVCKNHTTTTTTTLEYELSNFAKLTTRITTQSAAEVDTSPHTDTETHRDRDSNPGNIALATDLELPKGLPLSLSSRHHWNQLQSSLHALHHQQQQQQQQLRSYSSTSETNLEDKMSKPDSKLDKYAQRDRLGLWGTGDNEVVGSLSGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVR------------------------------------------------------AIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEP----IDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNN-KKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDD-LAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLDYPRSVPATYKM--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JIZ4-1", "uniprot_id": "E1JIZ4_DROME", "id": "E1JIZ4-1", "name": "Malic enzyme", "aln": "-----------------------------------------------------------MFSRPSLCGTVGKLCRCGTSATG----------------KTAVAAATVPTARHYHEVVG--------------DIICPS-------------------------------QVR---------------------------------------------GIDHIRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLSDLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDRGHIFDVMKNWPEPNVR------------------------------------------------------AICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLEDPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMVDIDGLLTKSRKVGNLDGHKIHYAKDINP----MSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADNNERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGD-KTFYPGQGNNAYIFPGVGLGVICTGTHHIPDEMFLIAAQELANFVEPSD-IERGSLYPPLSSIRNVSMNIAVGVTKCAYDRGLASTYPEPQDKRKWLENQLYNFNYESSMPASWVWPRMPYIKTRDLVPTKLYGKQKSEEVM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13697-1", "uniprot_id": "MAOX_RAT", "id": "P13697-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------MDPRAPRRRHTHQR---------------------------------------------------------------------------------------------------GYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVDSKGLIVKGR--ASLTEEKEVFAHEHEE----MKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDKH-LEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYSWPEEVQKIQTKVNQ-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06801-1", "uniprot_id": "MAOX_MOUSE", "id": "P06801-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------MEPRAPRRRHTHQR---------------------------------------------------------------------------------------------------GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGR--ASLTEEKEVFAHEHEE----MKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKH-LQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYPWPAEVQKIQTKVNQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48163-1", "uniprot_id": "MAOX_HUMAN", "id": "P48163-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------MEPEAPRRRHTHQR---------------------------------------------------------------------------------------------------GYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGR--ASLTQEKEKFAHEHEE----MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKH-LEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K4C6-1", "uniprot_id": "A0A0G2K4C6_RAT", "id": "A0A0G2K4C6-1", "name": "Malic enzyme", "aln": "--------------------------------------------------------------MGAALGTGARLTSLPRLACG-------SLRRQALSAPAQGCHSKSGPPRPVPLKKR---------------------------------------------------------------------------------------------------GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDNIKLFLQLPTQSSECEEHCLSVIWPLRILAHMPERTSHLQLMNPLASSQTSCFIPYNAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVRGKEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAVRKIWMVDSKGLIVKGR--SHLNHEKEMFAQEHPE----VNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYQVTEGRGIFASGSPFKSVTLEDGRTFIPGQGNNAYVFPGVALGIIAGGIRHVPDEIFLLTAEQIAQEVSEQH-LSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFIKSLIYTPDYDSFSLDTYTWPKEAMSVQKV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMF3-1", "uniprot_id": "MAON_MOUSE", "id": "Q8BMF3-1", "name": "NADP-dependent malic enzyme, mitochondrial", "aln": "--------------------------------------------------------------MGAALGTGARLTSVPRIACS-------SLRRQAPSAPAQGCHSKSGPPRPVPLKKR---------------------------------------------------------------------------------------------------GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDNIK------------------------------------------------------AVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVRGEEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAIKKIWMVDSKGLIVKGR--SHLNHEKEMFAQDHPE----VNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIVFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGRTFTPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQH-LSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFVKSLIYTPDYDSFSLDTYSWPKEAMSVQKV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16798-1", "uniprot_id": "MAON_HUMAN", "id": "Q16798-1", "name": "NADP-dependent malic enzyme, mitochondrial", "aln": "--------------------------------------------------------------MGAALGTGTRLAPWPGRACG-------ALPRWTPTAPAQGCHSKPGPARPVPLKKR---------------------------------------------------------------------------------------------------GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIK------------------------------------------------------AVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGR--SHLNHEKEMFAQDHPE----VNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQH-LSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSFTLDSYTWPKEAMNVQTV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K502-1", "uniprot_id": "A0A0G2K502_RAT", "id": "A0A0G2K502-1", "name": "Malic enzyme", "aln": "-------------------------------------------------------------------------MKWHLCAGI-------GRREKMFSRLRAVTTPCTLTCRRVHLKEK---------------------------------------------------------------------------------------------------GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLKKYQEKYCTFNDDIQGTAAVALSGLLAAQRVINKPISEHRILFLGAGEAALGIAKLIVISMMESGLSEEEAQRKIWMFDKNGLLVKGRT-ARIDSNQEPYAHAASEN--IPATFEDAVNKLKPSVIIGVAGAGPLFTPGVIKAMAAINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVRLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTSQLTDEE-LAQGRLYPSLANIQEVSANIAIKIAEYLYANKMAFRYPEPEDKAKYVKERIWRSNYVSLLPDVYDWPESSLKPPQIPE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KE1-1", "uniprot_id": "MAOM_MOUSE", "id": "Q99KE1-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "----------------------------------------------------------------------------------------------MFSRLRAVTTPCTLTCRRVHLKEK---------------------------------------------------------------------------------------------------GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLLVKGRT-ASIDSNQEPYAHAAPES--IPATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLTDAE-LAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYVRERIWRSNYVSLLPDVYDWPESSLTPPQITEEKLPH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23368-1", "uniprot_id": "MAOM_HUMAN", "id": "P23368-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "----------------------------------------------------------------------------------------------MLSRLRVVSTTCTLACRHLHIKEK---------------------------------------------------------------------------------------------------GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRK-AKIDSYQEPFTHSAPES--IPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEE-LAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PN55-1", "uniprot_id": "A5PN55_DANRE", "id": "A5PN55-1", "name": "Malic enzyme", "aln": "----------------------------------------------------------------------------------------------MLSRLSTSVRPCVSMCRWVHTKEK---------------------------------------------------------------------------------------------------GKPLMLNPRTNKGMAFTLKERQMLGIHGLLPSKIETQDTQAMRFQKNLKKMSDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIKDQGHIRSILDNWPDTSVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDVGTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQFEDFGNHNAFRFLKKYREKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALGIANLIVMAMMESGMSQADARKKIWMFDKYGLLVKDRA-YETDSNQEAFVHPDPGD--VKS-FLDAVNVIKPTAIIGVSGAGRLFTHDVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPFAPVSLEDGRILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEE-LSQGRLYPPLSNIREVSLQMAIKVVEYVYSKGMAFRYPEPVDKESYVRSVVWNTNYDSFLPDIYDWPGVSHTP--IVD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAF6-1", "uniprot_id": "A1ZAF6_DROME", "id": "A1ZAF6-1", "name": "", "aln": "-------------------------------------------------------------------MEFRRLHPLLRLASR--------------PLLSSSRRFSVYDDEMEQITRP---------------------------------------------------------------------------------------------------DWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVK------------------------------------------------------AICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGILTPESP--NPPEMGKIFIKSMEP----MKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVING-KRYRPAQANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQEL-LDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDICEFVKRSLYKFDYRNSLPTTWDYPVEPPTPKPKTKPKTKPKE-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36013-1", "uniprot_id": "MAOM_YEAST", "id": "P36013-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "------------------------------MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTRSHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEG----------------------------------------------------------------------------------------AIECPLESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVD-----------------------------------------------------YIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPS-AVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPV-----DGYRISENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGGAPGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*. *** :** : : .: * . . * : : : : ::. *:: .: .: :*::**** * . :. .:.. .:*: : . : : : : *:*. :**:** * .: *.:.*: * * ..: * :*: :****:. : .* :*:* * ** ::::*:.: : .::****. ** ::* **: ********.:. ::.: : . : .:: ***.*.:***. : *: .* .*::.* *:: : : ::*. ::* : . *. ::. * : * :*.***** *. . . *. . :..:**** .* .: ** ***:.*. : : : :: . . :: . * * : : :. : . : : :: ", "identical_positions": 95, "similar_positions": 157, "identity": "11.19%" }, { "cls_id": "homologset.agr.SGD:S000001515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q24537-1", "uniprot_id": "HMG2_DROME", "id": "Q24537-1", "name": "High mobility group protein DSP1", "aln": "-----------------------------------MEHFHQIQQTIQHYQQQLAAQQQQQVQQQQLQQH---------------------------------------QVVVQQNQQQAHQNSSNTTAGVGTQQL------------------------------FTYKMASSFPNPATTMAQVVATSNAAG---TTGYDYR-----------LNMAQAAAAAA------------VPGSQWWYS------------------------AANQGQVDANTAAQLQHQQQQQQQ----QQQQQQQQHQQQQQMQQQQQQQNVINSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQN-----YVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAER----------------------------------DKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQLEEQHD-------DDDGDGDDDENQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33417-1", "uniprot_id": "IXR1_YEAST", "id": "P33417-1", "name": "Intrastrand cross-link recognition protein", "aln": "MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQTPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQPTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFSEFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPATAAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLLPPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQQQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELSKLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNPTGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQQPLQQQQQQQQQQQHMLLADPTTNGSIIKNE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :** ::* :*: ** *** **** **: * **:*** :..**:. .*..: * * :::.. .**:.* : . :..*: . ::* : ** * ****** :* * :*. *:: * : .* .** *:*** ** ***** **:** ** :* ****:: :. :.: : : : . : : *.:: **: : * * . : * : : : : :. *::: . *:: :: * : *. :.. .***. ..*: * :: * .* **: *: :*:* :*.:* ::** * :* . :: * ::: *: *:. * : * . * :.:: :. :: * :** ::*:: * :*. :*:", "identical_positions": 111, "similar_positions": 133, "identity": "18.59%" }, { "cls_id": "homologset.agr.SGD:S000001516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z854-1", "uniprot_id": "D3Z854_RAT", "id": "D3Z854-1", "name": "TELO2-interacting protein 1 homolog", "aln": "MAVFDTPEEAFGVLRPVCVQLTKTQTV-------------ENVEHLQTQLQAISDTALQ-ELQQYILFPLRFALKTPGP--KRERLVQSVVECLTFVLSSTCVREQE-LLQELFSELSACLYS-PNSQKPAALSEELKLAVIQGLSTLMHSA----YRDIILTFYEPSILPRLGFAVSLLLGLAEQE-KSKQIKIAALQCLQVLLLQCDCQDHPRPLDELEQQQLGDLLASFLPGISTALTRVITG-DFKQGHSIVVSSLKVFYKTVGFIMADEQ-----------------------------LTRIPKVRAKPAVEHKVAALMIHREADWVKSTGGKLAILIKKIIDCVSVHPHWKVRLELVEFVEVLLFKCSQSLVESTGPLLKVLVGLVNDESSEVQAQCNTVLRRLADQKVVVGSRALADILSESLHSLATSLPRLMNTQDDQGKFSTLSLLLGYLKLLG-PKVHVILNSVAHVQRLSRALIQVLELEVADVKMVEERRWNSDNLSASAEASAARPWSRVQRRYFRCFTDERVFLLLRKICQLLGYYGDLY-LLVDHFMELYHTSIVYRKQAAMILNELVVGAAGLDVEDIHYECASTSPEELREIVKSILEEYTSQENWYLITCIEAEEE-EEVMMKQQGLQAVTSGVHTCQVVS-FPALSKPSPTICSMNSNIWQICIQLEGIGQFAYALGKDFRLLLMSALYPVLEKAGDQTLLISQVAASTMVDICHACGYNSVQHLINQNSDYLVNGISLNLRHLALHPHTPKVLEVMLRNSDASLLPLVADVVQDVLATLDQFY-DKR-AASFVSVLHALLAALAHWFPDSGSTGQLQQHSLEEVA-----------RQTPAASKAS-PTAEDIERFVLSYLQE-------KDMAEGNVSDLEAEEVLSEEQSVPPRVDESDALPDVEPPLPVHIQIAKDVMERCIHLLSDKNLKVRLKVLDVLGLCVEVLQTHKNQLLPLAHRAWPSLVHRLTSDDPLAVLRAFKVLQTLGSRCGDFLRSRFCKDVLPKLASSLVTQAPISARAGPVYSHTLAFKLQLAVLQGLGPLCESLDLGEGDLNKVADACLIYLSTKQPVKLQEAARSVFLHLIKVDPDSTWLLLHQLHCPVQQFTAPHPSLHPVQWQGATKPQNPYATNVCHLLLQLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V83-1", "uniprot_id": "TTI1_MOUSE", "id": "Q91V83-1", "name": "TELO2-interacting protein 1 homolog", "aln": "MAVFDTPEEAFGVLRPVCVQLTKTQTV-------------ENVEHLQTQLQAISDTALQ-ELQQYILFPLRFALKTPGP--KRERLVQSVVECLTFVLSSTCVREQE-LLQELFSELSACLYS-PSSQKPAALSEELKLAVIQGLSTLMHSA----YRDIILTFYEPSILPRLGFAVSLLLGLAEQE-KSKQIKIAALQCLQVLLLQCDCQDHPRPLDELEQQQLGDLLASFLPGISTALTRIITG-DFKQGHSIVVSSLKVFYKTVGFIMADEQ-----------------------------LTRIPKAQAKPVVEHRVAALMIHREADWVKSTGDKLAIFIKKIIDCVSVHPHWKVRLELVEFVEILLLKCTQSLVESTGPLLKVLVGLVNDESPEVQARCSTVLRRLADQKVVVGSRALADILSESLHSLATSLPRLMNTQDDQGKFSTLSLLLGYLKLLG-PKVHVILNSVAHVQRLSRALIQVLELEVTDVKMVEERRWNSDNLSASAEVSAARPWSRVQRRYFRCFTDERVFLLLRKICQLLGYYGDLY-LLVDHFMELYHTSVVYRKQAAMILNELVVGAAGLDVEDIHNKCPSMGPEELREIVKSILEEYTSQENWYLITCFEAEEG-EEVMMKQQGFQAVTSGVHTCQVVS-FPALSKPSPTICSMNSNIWQICIQLEGIGQFAYALGKDFRLLLMSALYPILEKAGDPTLLISQVATSTMVDICHACGYNSVQHLINQNSDYLVNGISLNLRHLALHPHAPKVLEAMLRNADASLLPLVADVVQDVLATLDQFY-DKR-AASFVSVLHALLAALAHWFPDSGSTGQLQQRSLEEEG-----------RQLPAAGEAS-TTAEDIEQFVLSYLQE-------KDVAEGNVSDLEAEEEV---QSAPPKVDENDTLPDVEPPLPTHIQIAKDVMERCIHLSADKNLKIRLKVLDVLGLCVEVLQTHKNQLLPLAHRAWPSLVHRLTSDDPLAVLRAFKVLQTLGSRCGDFLRSRFCKDVLPKLTSSLITQAPISARAGPVYSHTLAFKLQLAVLQGLGPLCENLDLGEGDLNKVADACVIYLSTKQPVKLQEAARSVFLHLMRVDPDSTWLLLHELYCPVQQFTAPHPSLHPVQLQGATQPQNPYATNVCHLLLQLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43156-1", "uniprot_id": "TTI1_HUMAN", "id": "O43156-1", "name": "TELO2-interacting protein 1 homolog", "aln": "MAVFDTPEEAFGVLRPVCVQLTKTQTV-------------ENVEHLQTRLQAVSDSALQ-ELQQYILFPLRFTLKTPGP--KRERLIQSVVECLTFVLSSTCVKEQE-LLQELFSELSACLYS-PSSQKPAAVSEELKLAVIQGLSTLMHSA----YGDIILTFYEPSILPRLGFAVSLLLGLAEQE-KSKQIKIAALKCLQVLLLQCDCQDHPRSLDELEQKQLGDLFASFLPGISTALTRLITG-DFKQGHSIVVSSLKIFYKTVSFIMADEQ-----------------------------LKRISKVQAKPAVEHRVAELMVYREADWVKKTGDKLTILIKKIIECVSVHPHWKVRLELVELVEDLLLKCSQSLVECAGPLLKALVGLVNDESPEIQAQCNKVLRHFADQKVVVGNKALADILSESLHSLATSLPRLMNSQDDQGKFSTLSLLLGYLKLLG-PKINFVLNSVAHLQRLSKALIQVLELDVADIKIVEERRWNSDDLNASPKTSATQPWNRIQRRYFRFFTDERIFMLLRQVCQLLGYYGNLY-LLVDHFMELYHQSVVYRKQAAMILNELVTGAAGLEVEDLHEKHIKTNPEELREIVTSILEEYTSQENWYLVTCLETEEMGEELMMEHPGLQAITSGEHTCQVTS-FLAFSKPSPTICSMNSNIWQICIQLEGIGQFAYALGKDFCLLLMSALYPVLEKAGDQTLLISQVATSTMMDVCRACGYDSLQHLINQNSDYLVNGISLNLRHLALHPHTPKVLEVMLRNSDANLLPLVADVVQDVLATLDQFY-DKR-AASFVSVLHALMAALAQWFPDTGNLGHLQEQSLGEEGSHL--------NQRPAALEKSTTTAEDIEQFLLNYLKE-------KDVADGNVSDFDNEEEE---QSVPPKVDENDTRPDVEPPLPLQIQIAMDVMERCIHLLSDKNLQIRLKVLDVLDLCVVVLQSHKNQLLPLAHQAWPSLVHRLTRDAPLAVLRAFKVLRTLGSKCGDFLRSRFCKDVLPKLAGSLVTQAPISARAGPVYSHTLAFKLQLAVLQGLGPLCERLDLGEGDLNKVADACLIYLSVKQPVKLQEAARSVFLHLMKVDPDSTWFLLNELYCPVQ-FTPPHPSLHPVQLHGASGQQNPYTTNVLQLLKELQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH80-1", "uniprot_id": "Q9VH80_DROME", "id": "Q9VH80-1", "name": "", "aln": "---MMHLEWYVTKIKPAVEGFIKEPSK-------------DTLSVVERAIEGFNFGEMR-IYQVQTVVPLVVKLDELTG--ENQELRTSLMNCLSNIVSKTYLADEKGLRSILVVVLQQVRDS-KTASMRPNLSEEIKLAAVQCIFEALRRS----TTDVVESFYVKETAMVIGQILIMLLEIIEQE-KYRKLVQTAIQCLMMVFYVHDESDQ---VDVVLRSQVANTIFIFLPKVLIVLFKTSMK-DDKVGETIKSMAIQALGRIICIMFEETTNEFIKMRYDGDAFRKLFKNNEEAHQCDFTFFASKKATTEQNEERLHQMQTELRSHQWVAATSRHLRPIFAEMS-ILRTHSAIRVRESYSDMCCLLLKHCAYNLRGNFLHVLESVLALSEDENEKIAQRCRDTLLLLQQQASSQ--DIFDENAEMLLDAHLNKWPRILHRCEDNEQFAELLFFKGFLRNVNTDKLQLLLLVPKNLEMFVTCLLTALDQRPTRDLLNEEYSLR--RIREGDSKGLAAELAKLPWRQFKYLSSRRTVDILYDIGALLGTEPTINRLVFDYCQEMIQQRSPSMNECVLLLTLMVTPQE----KKARGSRLVLAKLFLDQILRDEHWNLALQPDSAWRLKVNKPTHWFEDRTPGIYSSAIEVRTQDCDSDDEQTEVVGSRVTIADAQFNVLHTCLILDAVGHCARFIGDTFDRHIFLSLHKVLLKVASSNTIVHQAASFAFVSMQYALKYAEPSHFIECSTDYITFHLNALLKRSPDSTAAVDILTVVLQYSTRGNVPHLDSLFQTIREECSKSH-QTTNVHSYLRVFKSFLNHVSDWHDDAAAEVDTELPMQVDEE-------------------------QNVLSTWMSVLER-------PKLLKDLNGDTNMGDAEEPAKDEADDADDTEEKP-TKPVLPRHVEMVKDILGQVIKFISTADQGQQIAALECFSSGLPLLADYEDELLPLVHLVWQPLIEKFRQKDALVLNRCFTLLHLLGVHAKDFILKRSLSDVIPQLK-QFLKTASLHSSTETSQAQTQEYKLQLKLLKSLADFILGLQIEGRHLHEIMSTVVIYLSQIQPQELQTPARAFFLQLISYNGPFVYVTLLQRAHLQDYQANVNQIFEVMGFSIASGRDLG-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36097-1", "uniprot_id": "TTI1_YEAST", "id": "P36097-1", "name": "TEL2-interacting protein 1", "aln": "---MNSDTNAFKDIRISCVELSRIAFLPTESFDPNSLTLLACLKKVEEKLSAYEDDSLSPKFADYVFVPIASLLKQPALGESQTEYVLLIIFHLLRTCWSSNGKFSEQLGQQLFPLITFLVSSDKDNQKLITRSDEFKYAGCLVLHQFFKSVRSQRYHKEFFSNSKPNLLPALGHSVTILLKILEQSPQNNELQFKALASLEVLFQDIISDGE--------------MLSFILPGNVSVFAKILTKPGRQIHYKVCVRTLEVLAKLLVLVYDDFS----------------------------LDIKVNKLTDIRELSDTKLKHEINQSFMFNGPIVLLRTDGKTHRDTSWLTATSGQINIALEAFIPKLLKRNNESIDEALATFVSILLTRCENSLNNCEKVLVSTLVHLERDPMSKLPSHLVK-LKEVVNEDLHKLSDIIR-FENADRLSSLSFAITILEKNN--------ERDTMINEVVRCLFESLNESIEPPSLIN-----------HKERIIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKF---TYHMGSLLLERHILNDVVTELISEQVDSPRTQKIVALWLSTNFIKAMEKQPKEEEVYLQFESDAN----------------YSSSMVEEVCLIVLEFCNELS--QDISMEIEGKGIKKSDEFAVCTVLFSIETICAVMREEFQPELIDYIYTVVDALASPSEAIRYVSQSCALRIADTLYHGSIPNMILSNVDYLVESISSRLN-SGMTERVSQILMVICQLAGYETIENFKDVIETIFKLLDYYHGYSDLCLQFFQLFKIIILEMKKKYINDDEMILKIANQHISQSTFSPWGMTDFQQVLNILDKETQVKDDITDENDVDFLKDDNEPSNFQEYFDSKLREPDSDDDEEEREEEVEGSSKEYTDQWTSPIPSDSYKILLQILGYGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVASTWDSIIQCVLCSDYSIVQPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHNHEK-----------KSISKHVKFPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVP-------------VEKISSMSLIVGDIVWKIRNIN----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: : : :. :: :.. . : ..*: *. .. . :: * .: .: * . *. : * . *:*:* * : :: . . : . :* : :** : **. : .:: *: .* ::: ... : :** .: : . : .: ::: : : : :: : * . :. : . . . ::. : ** : .: .:. :: ::. : .* : : : . . :. . . ::. :: ::: * : *. . :: . .*: *: : : . *. : . . . * : :. : .: . . ::. * . . : : : .. . *: . . : : * * .: . : . * :: :: :: .. . : .: : : : : . ::* . **:. :. *. . .:* .: : : : . .:.: : . : . .:. ::: :: : . . : . : :. *: . .. : : : :. .. ..* . :: ::: :: : . :: * : . :* .: *: . .* .::. . . : . . :. : . **: .* . .:: : : :.:. : * .: : :. : : . .: : : : . : . ", "identical_positions": 49, "similar_positions": 296, "identity": "4.2%" }, { "cls_id": "homologset.agr.SGD:S000001518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K542-1", "uniprot_id": "A0A0G2K542_RAT", "id": "A0A0G2K542-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSQMVFNLSKAMSQDGASQFQEVILQELELSVKKELEKILTTATSHEFEHTKKD--LDGFRKLFHRFLQEKGP--SVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNPKTLDGG---LNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZJ5-1", "uniprot_id": "UGPA_MOUSE", "id": "Q91ZJ5-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSRFVQDLSKAMSQDGASQFQEVILQELELSVKKELEKILTTAASHEFEHTKKD--LDGFRKLFHRFLQEKGP--SVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLGAVKRLQEQNAIDMEIIVNPKTLDGG---LNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16851-1", "uniprot_id": "UGPA_HUMAN", "id": "Q16851-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKD--LDGFRKLFHRFLQEKGP--SVDWGKIQRPPEDSIQPYEKIK-ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKR-CEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGG---LNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGS-SFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDY2-1", "uniprot_id": "F1QDY2_DANRE", "id": "F1QDY2-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "---------------------------------------------------MLCLSKELLSNSN---GMAQFQEVMRQQLESSMHVELEKLLSTAKGAGAEVSKKD--FEGFRKLFHRFLQVKGP--SVEWPKINRPPEDSIQPYDKIK-AKGLPDNIADSLNKLVVVKLNGGLGTSMGCKGPKSLISVRNENTFLDLTVQQIEHLNKTYNADVPLVLMNSFNTDEDTKKILQKYTHHRVKIHTFNQSRYPRINKESLLPVAKDMGMTGENGDVWYPPGHGDIYASFYNSGLLEQLIAEGKEYIFVSNIDNLGATVDLYILNHLVSQPNGKR-CEFIMEVTDKTRADVKGGTLIQYDGKLRLLEIAQVPKAHVDEFKSVTKFKIFNTNNLWISLSAIKRLQEQNAMDMEIIVNPKTIDGG---LNVIQLETAVGAAIKCFDNALGINVPRSRFLPVKTTSDLLLVMSNLYSLDAGSLTMSEKREFPTTPHVKLGS-SFTKVQEYITRFESIPDMLELDHLTVSGDVTFGKHVSLKGTVIIIANHGDRIDIPAGSMLENKIVSGNLRILDH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B230-1", "uniprot_id": "A0A8M2B230_DANRE", "id": "A0A8M2B230-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "MTLFTLLNAVNDRNSTECFMIGPSRSSSTSDWSVSKHQTHTPHSCDTSAVRPRCTVSEHLYRSSPNAGMAEFQEKLRLQHENSMHTELEKLLSTAKTPEAEISRKD--FEGFKKLFHRFLQEKGP--SVDWAKIQRPPEDSIQPYEKIK-LKGLPADVASSLNKLAVLKLNGGLGTSMGCKGPKSLISVRNENTFLDLTVQQIEHLNKTYNADVPLVLMNSFNTDEDTKKILQKYTHHRVKIHTFNQSRYPRINKESLLPVATNMGLTGENEEAWYPPGHGDIYASFYNSGLLDKLIAEGKEYIFVSNIDNLGATVDLHILNHLMSQPNDKR-CEFVMEVTDKTRADVKGGTLTQYDGKLRLLEIAQVPKAHVDEFKSVTKFKIFNTNNLWMSLPAIKRLHEKNAMDMEIIVNPKTLDGG---LNVIQLETAVGAAMKSFDNALGINVPRSRFLPVKTTSDLLLVMSNLYSMNAGSLTMSPKREFPTTPHVKLGS-SFTKVRDFLKRFESIPDMLELDHLTVSGDVTFGKQLTLKGTVIIIANHGDRIDIPAGAMLENKIVSGNLRILDH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSW1-1", "uniprot_id": "Q9VSW1_DROME", "id": "Q9VSW1-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "------------------------------------------MPSGIRPIDVLLERAGVRGHQRAPSDSKEFHEVTKRDALRLLEHDVDRLLETTEKARQPALKAE--MGRFADLFGRFIQEEGP--ALDWNKIQKLPENAVMNYSNLKSPKNEQNEIRNMLDKLVVIKLNGGLGTSMGCHGPKSVIPVRSDLTFLDLTVQQIEHLNKTYDANVPLVLMNSFNTDEDTEKIVRKYKGFRVQIHTFNQSCFPRISREHYLPVAKDFDVEKD-MEAWYPPGHGDFYDTFRNSGLLKKFIEEGREYCFLSNIDNLGATVDLNILNKLVGEERATTPVEFVMEVTDKTRADVKGGTLIQMENKLRLLEIAQVPPEHVDDFKSVKTFKFFNTNNIWANLAAIDRVLRERTLNMEIIVNNKTLENG---TRVIQLETAVGAAMKCFDGAIGINVPRSRFLPVKKSSDLLLVMSNLYTLKNGSLVMSPQRMFPTTPLVKLGENHFSKVKEFLGRFANIPDIIELDHLTVSGDVTFGRGVSLRGTVIIIANHGDRIDIPAGAILENKIVSGNMRILDH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32861-1", "uniprot_id": "UGPA1_YEAST", "id": "P32861-1", "name": "UTP--glucose-1-phosphate uridylyltransferase", "aln": "----------------------------------------------------MSTKKHTKTHST-----YAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIIS---QQPENVSN-LSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEY---DSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETG-----AEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSR-FGPNPLIKLGS-HFKKVSGFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.. :. :::: :: : : : * ** *:: :.. :::* **: : : *. :. :: . *.**.*:************ ****:* **. *****:*:***:**: *:::***:********:**:::::**. *::* :**** :**: :: **:..: . :.********:: :: ** *. :* :*:* *:** ********* ***::: *::**:*:*********** . :.::**:*:**** *:*:**.: .*. *****:* .* *:.*: .. ::**** * **: . .*:***** ***:: *:.: *: **********. ****** *:*: :. *** :. .* * . * :***. *.** : *: **.::******::*:* :*: ::*:*****:...*.:**** *::*** :*:**::**:*", "identical_positions": 215, "similar_positions": 151, "identity": "37.72%" }, { "cls_id": "homologset.agr.SGD:S000001522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIL4-1", "uniprot_id": "A0A8I6GIL4_RAT", "id": "A0A8I6GIL4-1", "name": "", "aln": "MAVKMAVAAWLQVSPVIFLLLGAQP----FPLSFLGAGPAPVFAADRS-KWHVPMPSGKSYFNFGKILFRNTTIVLKFDGEPCD--QSLNITWFLKSADCYNEVYNFKADEVETYLENLKEKKGLSGRYQTSSKVFQNCSELYKAQSFSGDLMHRLPLLGEKQEAKENATNLTFTGDKIAMHEPLQTWQDAPYIFIVHVGISSSKESPKENALSNLFTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGMFEKAVFYAEFQNIRYKG--ESVQNALVLAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVVAG--ALYLLFSGMEGVLRVTGAQTDLAS--LAFIPLAFLDTALCWWIFISLTQTMKLLKLRRNIVKLSLYRHFT----NTLILAVAASIVFIIWTTMKFRIVTCQSDWRELWVDDAIWR-LLFSMILFVIMILWRPSANNQRFAFSPLSEE--DEEDEQKEPMLKES--FEGMKMRSTKQEPN-GNSKANKTQ--EDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERSKME------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXN9-1", "uniprot_id": "GPHCC_MOUSE", "id": "Q8BXN9-1", "name": "Golgi-pH regulating cation channel", "aln": "----MAVAAWLQVSPVIFLLLGAQP----FPLSFLGAGPAPVFAADRS-KWHIPMPSGKGYFNFGKILFRNTTILLKFDGEPCD--QSLNITWFLKSADCYNEIYNFKADEIESYLENLKGKKGLSGRYQTSSRLFQNCSELYKAQSFSGDFTHRLPLLGEKQEAKENATNVTFTGDKIAMHEPLQTWQDAPYIFIVHVGISSSKESPKENALSNLFTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGMFEKAVFYAEFQNIRYKG--ESVQNALVLAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVVAG--ALYLLFSGMEGVLRVTGAQTDLAS--LAFIPLAFLDTALCWWIFISLTQTMKLLKLRRNIVKLSLYRHFT----NTLILAVAASIVFIIWTTMKFRIVTCQSDWRELWVDDAIWR-LLFSMILFVIMILWRPSANNQRFAFSPLSEE--DEEDEQKEPMLKES--FEGMKMRSTKQEPN-GTSKVNKAQ--EDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERSKME------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBN3-1", "uniprot_id": "GPHCC_HUMAN", "id": "Q8NBN3-1", "name": "Golgi-pH regulating cation channel", "aln": "----MAAAAWLQVLPVILLLLGAHP----SPLSFFSAGPATVAAADRS-KWHIPIPSGKNYFSFGKILFRNTTIFLKFDGEPCD--LSLNITWYLKSADCYNEIYNFKAEEVELYLEKLKEKRGLSGKYQTSSKLFQNCSELFKTQTFSGDFMHRLPLLGEKQEAKENGTNLTFIGDKTAMHEPLQTWQDAPYIFIVHIGISSSKESSKENSLSNLFTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGMLEKAVFYAEFQNIRYKG--ESVQGALILAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVVAG--ALYLLFSGMEGVLRVTGAQTDLAS--LAFIPLAFLDTALCWWIFISLTQTMKLLKLRRNIVKLSLYRHFT----NTLILAVAASIVFIIWTTMKFRIVTCQSDWRELWVDDAIWR-LLFSMILFVIMVLWRPSANNQRFAFSPLSEE--EEEDEQKEPMLKES--FEGMKMRSTKQEPN-GNSKVNKAQ--EDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERSKME------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96K49-1", "uniprot_id": "TM87B_HUMAN", "id": "Q96K49-1", "name": "Transmembrane protein 87B", "aln": "--MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNL-EELFQKHKLSVDED---FCHYLKNDNCWTTKNENLDCNSDS----QVFPSLNNK----ELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLN-------VSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTG--LSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLG--LLYLIFAAVEGVMRVIGGSNHLAVV-LDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFK----NTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWS-FLFSLILIVIMFLWRPSANNQRYAFMPLID---DSDDEIEEFMVTSENLTEGIKLRASKSVSN-GTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7B6-1", "uniprot_id": "D4A7B6_RAT", "id": "D4A7B6-1", "name": "", "aln": "--MAAACRSMASLLPGLLCRLPAGAQMLRVALCLLCWVPAAVDAVPELGLWTRTVNDKSGPLIFRKTMFNSTDIRFSVKSFSCSGPVKFTIEWHLKYHTCHNEYPELEEELFQKHELHADGD---VCAYFKNIDCWTTKSENLDCSSDS----QAFPSLNNK----ELTGIRNISSQEGSMDVVARTQKDGFHIFIVSIKTEKTDAIWDLN-------VSLSMVGPHGYISASDWPLMIFYMVMCIVYILYGVLWLLWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNINSTG--LSTQGLLIFAELISALKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLG--LLYLIFAAIEGVMRVIGGSKHLAVA-LTDIVLAVIDSISVWFIFISLAQTMKTLRLRKNTVKFSLYRHFT----NTLIFAVLASIVFMVWTTKTFRIAKCQSDWMELWVDDAFWS-FLFSLILIVIMFLWRPSANNQRYAFMPLID---DSDDEVEEFMVTSENLTEGIKLRASKTVSN-GTAKP-TSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEIAEKMFSSEKIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VQ34-1", "uniprot_id": "Q9VQ34_DROME", "id": "Q9VQ34-1", "name": "GOST seven transmembrane domain-containing protein", "aln": "------MQGSATLLVVALALL---------------LGPASTAGKSDPGMVDVLVTTDLPSIREQRPLLANTKIYAQIKGCTSNVESNLTITFRLTEHPCIFDDRTLQAIAQNATLQKNATINNVITEITRTYPCNGLIVLAINKDKVVEG--SAIPTPEPKHPMLEHKHPLSPTTN-----PIASVKEDGIYEIEVNIAAGPSAQFSAVV--------HIEFLGPHGFISAIDWPFLPFYLIMCIVYVIFGIIWLFVSFAQWRDLLRIQFWIGGVILLGMLEKAFFYAEYQTLTNKG--VAVQHAELVAEFVSCAKRTLARMLVIIMSLGFGIVKPRLGPMLHRVVGVG--TLYFVLACVESYLRITNVKTDRSELLVASIPLAVLDTGICWWIFTSLVQTTRTLRLRRNMVKLSLYRHFT----NTLIFAVIASVIFMLFALRLRRVENCTPGWRDIWVDTGFWH-ILFSVLLLVIMILWRPTNNNQRYAFTPLLDNPEDEDDEDEEDQFVAD--AYGVKMRGQNGTPKTSTTSRNATTTEEDDLRWVEENIPSSMADSALP-ILDSDEEIINTKFEVSKMQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32857-1", "uniprot_id": "PTM1_YEAST", "id": "P32857-1", "name": "Membrane protein PTM1", "aln": "----MRVYQFCRPFQLFTCFL----------------CYLLVFVKANKEKISQKNYQVCAGMYSKEDWKGKIDPFISFNLKKISGLSDESDPGLVVAIYDFQDFEHLGVQLPDEEMYYICDDYAIDIGICEEENRDEFIVQDVVYDPYT----STNRSLANP--------IMTFSQNEVGLHDTRYPIKETGFYCVTAFRSSTSTKFNAVVN----------FRNAYGQLAGTEINKLPLYGLLAVAYVVAMALYSFAFWKHKHELLPLQKYLLAFFVFLTAETIFVWAYYDLKNEKGDTAGIKVYMVFLSILTAGKVTFSFFLLLIIALGYGIVYPKLNKTLMRRCQMYGALTYAICIGFLIQSYLTDMEAPSPLILITLIPMALALIIFYYMIIRSMTKTVIYLKEQRQIVKLNMYKKLLYIIYASFLSVLAGSIVSSFIYVGMNTIDMIEKNWRSRFFVTDFWPTLVYFIVFVTIAFLWRPTDTSYMLAASQQLPT---DPENVADFDLG--------DLQSFDDQDD-ASIITGERGIDEDDLNLNFTDDEEGHDNVNNHSQGHGPVSPSPTK-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . ... . . . : : : : . . : :: . . . : . ..: :: : : :: ::.:.*:: :: :::* :* :: ..:.: *. ..:: :: .* . : :. .:::. * ::: *::*::**:*** *:*. : : * : . : . . . : * :*. : *: *:.:* *: ::: **:.:*::: ::: .: .*:: : .* . :. :* ::: :::..* .****: .. * . :: : . .::. . . .. ::**. : .. : .. . ", "identical_positions": 36, "similar_positions": 156, "identity": "6.1%" }, { "cls_id": "homologset.agr.SGD:S000001523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA85-1", "uniprot_id": "D3ZA85_RAT", "id": "D3ZA85-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "------MAAAERAWGAAVGVARLCRRLCHVAT-PHAFKKQPLHQ------YVQRPLFPLRTPLYNTVRFMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPP--------------GEAGSSEEDDEVVAMIKELLDTRIRPTVQEDGGDVIYRGFED--GIVRLKLQGSCTSCPSSIITLKSGIQNMLQFYIPEVEGVEQVMDDE--------ESDEKEANSP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ23-1", "uniprot_id": "NFU1_MOUSE", "id": "Q9QZ23-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "------MAAAERAWGAAVGVVRLCRRFCHVAT-PHTFKKQPLHQ------YVRRPLFPLRAPLCNTVRFMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPPPP------------GEAGS-EEDDEVVAMIKELLDTRIRPTVQEDGGDVIYRGFED--GIVRLKLQGSCTSCPSSIITLKSGIQNMLQFYIPEVEGVEQVMDDD--------ESDEKEANSS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMS0-1", "uniprot_id": "NFU1_HUMAN", "id": "Q9UMS0-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "-----MAATARRGWGAAAVAAGLRRRFCHMLKNPYTIKKQPLHQ------FVQRPLFPLPAAFYHPVRYMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPS--------------GEAGS-EEDDEVVAMIKELLDTRIRPTVQEDGGDVIYKGFED--GIVQLKLQGSCTSCPSSIITLKNGIQNMLQFYIPEVEGVEQVMDD---------ESDEKEANSP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8SY96-1", "uniprot_id": "NFU1_DROME", "id": "Q8SY96-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "MSKFLSQAALNTLRNTRLGSRQLVRSFKGISN--TRNHRIPAHQESGCGHSVGCGLLELRMPVACR-RSMFIQTQDTPNPESLKFLPGV-DVLGKGNTYDFPNGTTAH----NSPLAKLLFR-VEGVKGVFFGADFVTISKQ-EGAEWSLIKPEVFAVIMDFFASGLPVLNDAQPN--------------ADTEILEDDDETVMMIKELLDTRIRPTVQEDGGDIVFMGYEG--GVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDEADRMIESEFERFEKNLKTLKQQEPSGGGPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B8A6A3-1", "uniprot_id": "B8A6A3_DANRE", "id": "B8A6A3-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "-----MAASIRWSLQRFVRSNHLRYPVNDRNQ---CYSLWAARR-------IQHQQNEFKS---FSVRKLSILTQDTPNPRSLKFLPGK-PVLGTG-TQDFPTSASAE----SSPLARDLFQ-ISGIKSVFYGPDFITLTKTDDDVEWTDIKRHAIEVISKFFEGGEAITTGAAHA---------------ESSVTEDDDEIVSLIKELLDTRIRPTVQEDGGDVIFKGFED--GTVKLKLVGSCTGCPSSTVTLKNGIQNMMQFYIPEVDNVEQVQDEVDEINMKVYTELEKKLQDV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32860-1", "uniprot_id": "NFU1_YEAST", "id": "P32860-1", "name": "NifU-like protein, mitochondrial", "aln": "----------------------MFKSVAKLGK---------------------SPIFYLNSQ-----RLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKD-RMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * : * * *** .:***:. :* . : .: : * **: :* *::.:: * **:*:.* .*. :* . : . : * : . . *:*:* :*:**:******:: *****: : *:: * * *:: *:*:.*.** :*** *::.*::.*: **. * *: * **: : ", "identical_positions": 62, "similar_positions": 63, "identity": "20.06%" }, { "cls_id": "homologset.agr.SGD:S000001524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGS4-1", "uniprot_id": "CHMP3_RAT", "id": "Q8CGS4-1", "name": "Charged multivesicular body protein 3", "aln": "MGLFGKTQEKP-PKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKEVCVVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQ-EEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPAGAMAASE-GDEEDDEEDLEAMQSRLATLRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ10-1", "uniprot_id": "CHMP3_MOUSE", "id": "Q9CQ10-1", "name": "Charged multivesicular body protein 3", "aln": "MGLFGKTQEKP-PKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKEVCVVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQ-EEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPAGAMAASEEGEEEEDEEDLEAMQSRLATLRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3E7-1", "uniprot_id": "CHMP3_HUMAN", "id": "Q9Y3E7-1", "name": "Charged multivesicular body protein 3", "aln": "MGLFGKTQEKP-PKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQ-EEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASE--DEEEEEEALEAMQSRLATLRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY88-1", "uniprot_id": "CHMP3_DANRE", "id": "Q6NY88-1", "name": "Charged multivesicular body protein 3", "aln": "MGLFGKTQEKP-PKDLINEWSLKIRKEMRVIDRQIRDIQREEEKVKRSIKDAAKKGQKDVCIILAKEMIQSKRAINKLYASKAQMNSVLLSMKNQLSVLRVAGALQKSTEVMKAMQSLVKIPEIQATMRDLSKEMMKAGIIEEMLEDTLEGMDDE-EEMEEAAEAEVDKILFEITAGALGKAPSKVTD-LPDPVAIGATAAPE--EESEEEEEIEEMQSRLAALRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN02-1", "uniprot_id": "Q9VN02_DROME", "id": "Q9VN02-1", "name": "", "aln": "MGLFGRTPSKD-PKEQVQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAKEIVNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDMSKEMMKAGIIEEMLDETMDSLEES-EELEEEASKEVDKVLWEITDGKLGEAP-LPPEATPADKASASAARVEAEQDDEEGEELQEMQSRLASLRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36095-1", "uniprot_id": "VPS24_YEAST", "id": "P36095-1", "name": "Vacuolar protein-sorting-associated protein 24", "aln": "MDYIKKAIWGPDPKEQQRRIRSVLRKNGRNIEKSLRELTVLQNKTQQLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLSNQMADSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMDEAVDEEVNKIVEQYTNEKFKNVDQVPTVELAANEEEQEIPDEK--VDEEADRMVNEMRERLRALQN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :: **: .. :**: . :::.:*.: ::*.:: :*.:*:*.: . : ***: . .: .::*:*:*:::*: : :.: : ::. : .*: ::: ::***: *:: * ::.**:**:***.**:::*::.: : **::* .. *::::: : * : :. . . . : :.: . :: *:.** :*:.", "identical_positions": 42, "similar_positions": 104, "identity": "18.58%" }, { "cls_id": "homologset.agr.SGD:S000001528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89044-1", "uniprot_id": "PRI2_RAT", "id": "O89044-1", "name": "DNA primase large subunit", "aln": "-------------------------MQF--SGRTRKKLRLAGDQRNA------CYPHSLQFYLQPPTENISLTEFESLAFDRVKLLKAIENLGVSYVKG-TEQYQSKLEAEIRKLKF-SYRENLED--------EYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFSILPKDKVQSFLKDTHL-HFEAISDEEKTLREQDIMASSPSLSGVRWES------------ESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLSHLSHSYTGQDYSTQKSTGKISLDQIDSLSTK---------SFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKG-KMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPSQGDFHGCPFRHSDAELLKQKMQTYKIPASGISQILDLVKGNHYQVACQKYFEMTHNVDDCGFSLNHPNQFFFESQRILTGGKDIKKEASHPETPQHKPSTQKTKDATSAL----------ASLDSSLEMDLEGLEDYFSK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33610-1", "uniprot_id": "PRI2_MOUSE", "id": "P33610-1", "name": "DNA primase large subunit", "aln": "-------------------------MQF--SGRIRKKLRLAGDQRNA------SYPHSLQFYLQPPTENISLTEFENLAFDRVKLLKAIENLGVSYVKG-TEQYQSKLEAEIRKLKF-SYRENLED--------EYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFSILPKDKVQSFLKDSHL-HFEAISDEEKTLREQDIMASSPSLSGIKLES------------ESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQKNTGKISLDQIDSLSTK---------SFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIRG-KMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPGQGDYHGCPFRHSDAELLKQKMQSYKIPASGISQILDLVKGNHYQVACQKYFEMTHNVDDCGFSLNHPNQFFFESQRILTGGKDIKKEISQPETPQHKPSTQKTRDAASAL----------ASLDSSLEMDLEGLEEYF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49643-1", "uniprot_id": "PRI2_HUMAN", "id": "P49643-1", "name": "DNA primase large subunit", "aln": "-------------------------MEF--SGRKWRKLRLAGDQRNA------SYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKG-TEQYQSKLESELRKLKF-SYRENLED--------EYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQL-QFEAISDEEKTLREQEIVASSPSLSGLKLGF------------ESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTK---------SFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKG-KMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKISPGGISQILDLVKGTHYQVACQKYFEMIHNVDDCGFSLNHPNQFFCESQRILNGGKDIKKEPIQPETPQPKPSVQKTKDASSAL----------ASLNSSLEMDMEGLEDYFSEDS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6P2-1", "uniprot_id": "A0ACD6B6P2_DANRE", "id": "A0ACD6B6P2-1", "name": "DNA primase large subunit", "aln": "-------------------------MQF--SGR---RKKLISSSQSD------LYDHCLQFYGQPPLDNISLIEFETFAVERLKLLKTVENLGVSYVKT-TDQYIKKLEAEFLSLNF-PFRAEVDDRKVPGVTSEYEKRRKDHISHFILRLAYCQTEDLRRWFIQQEMDLFRYRFGILSSKHKTEFLHKNNL-KYETVSAEEKKYLRDKLINSSYGLSGITLEE------------YDFYRVPFQDALDLVRTRKVYLLAGNAYIPQNEIVTIVLNDFRTRLSKALAVTARSLPAVQSDERLQPLLSHLSHAYVGQDYSIQKNVGKISLEQIDPLSGK---------SFPLCMRHLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQAMQFWRSEFVKG-KVDADKFDKAYAYSIRHMFGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKIAPGGINQILELVKGMHYQLACQKYFELTHSVEDAGFSLNHPNQYFTESQKLLGGGQGIKKEVEMSQKSQENP-----PSASRPS----------QANPKQAQEEMGDLDSFFQDE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPH2-1", "uniprot_id": "PRI2_DROME", "id": "Q9VPH2-1", "name": "DNA primase large subunit", "aln": "-------------------------MEFGLKKRARHEVKVEVASLET------KYPHNVMLYHYPPTEDVHIDEFEELALERLRLLRVLDRASTRNLRVLSDEWKEIVSADLTREGLRSYLRLCSTGGSAKHEADIQTRRRDYLSHFILRLAYCRSEDLARWFVAREMELFRYKFAALSSFEVKQFLEANGF-EIHPLTEAQKDEVKDGLYESTVGQSVAKIEL------------LDFYKVPFTQVLDLVRGRRCFLKAGYAYVNTHDLVSLVGTKQQDEIEQGLQAAKTMVEDVEADERISRTLKALHNSYTGRDYTVCRDA-AVPIESLDQLSKT---------SMPLCMRMCHEHIRANHHIKHSGRMQYGLFLKGIGVALEDSLRFWREEFTK--KMDADKFTRSYEYNIYHNYGKKGSMVNYTPYSCAKIIK-DVAGPGDCHGCPYKNMDQGSLKTKLSSYGLSASAIDEVMFFVSRGHYQIGCGKYFQLTHNSP-VEPSINHPNNYFEESQ-IAMGNRQKRANGSAPPKARIRPDIKGHGDRSMLMGDDDDELWRIAETQERIMQSQKDISEAFNDDLDLTQIDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20457-1", "uniprot_id": "PRI2_YEAST", "id": "P20457-1", "name": "DNA primase large subunit", "aln": "MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSSEEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSI--KEIETIIKPQFQKLLPFNTES-------------LEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKAN-QFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSRQLQKKQQKLEKEKLFNNGNH------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . . . * : :* ** :: : :** *.:*:::* :: .: :..:: : *::*: *******.:*::::* . *: * *:: :* *.. . .*:. : . :: :* . : : . .. ::** :.::*. * :* * **: : : :: .. :.: * : : :: *:*: *. * .*. *:. .. : * :. . * *:: : :: ***::: ** * .*******:: :::::** . * : :: :** : * *.: * :* :*. :*.*:.* .:: .. ** ****::. . *. :: : :. . * .:: . .* :.* * *:: *. .:.. .: . : . : : : . ", "identical_positions": 84, "similar_positions": 163, "identity": "14.19%" }, { "cls_id": "homologset.agr.SGD:S000001530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0PGW2-1", "uniprot_id": "DEN11_RAT", "id": "Q0PGW2-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSVPQDPALQAGGWVRGGSG----GGRVAAEAPRRREPEEPAPPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKVQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGGSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKLNSADRE--KYRRLNEQRQMLLYSQEVEGDYSPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLMDLLEAYGIDVMLVIDNPCCP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHG7-1", "uniprot_id": "DEN11_MOUSE", "id": "Q3UHG7-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSVPQDPALQAGGWVRGGSG----EGRVAAEAPRRREPDEPAPPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKVQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGGSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKINSADRE--KYRRLNEQRQMLLYSQEVEGDYSPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLMDLLEAYGIDVMLVIDNPCCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1U4-1", "uniprot_id": "DEN11_HUMAN", "id": "A4D1U4-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSLPQAPQPQAGGWGRGGGG----GARPAAEPPRRREPEEPAAPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKIQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGSSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKINSADRE--KYRRLNEQRQMLLYSQEVEEDYNPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLLDLLEAYGIDVMLVIDNPCCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LX49-1", "uniprot_id": "DEN11_DANRE", "id": "Q1LX49-1", "name": "DENN domain-containing protein 11", "aln": "MVEQSDRAPLLDWEEIPPAELAPSVPSPDTGDSLQSGLSSYPTEATLGADITLNTSPTRPSSVAAVHSPHKQHSGPGGDALAEEDEPGDCAFHGLSVRDRRITGWEEKDQIVAVFVVTFDTRSGNMIEWCLPHD---VNLEGVEFKSMASGSHRISSDFIYFRKG------------------CYFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLQCPGQYSPLEAFY-----EDKKAVLPSGGNGLVTACPTSALAPIVNRCMHPEMKITHPAGCMSQFIRFFGEQIMVLWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSIPG--MGVSVPEF--RPFFYINVADIPALETELS---YVACTTEKIFEEKKELYDVYIDNQNVKTHRESLQPLLRLNSADRE--KYRKLCEQRQLLLYSQEVDGDCTSNE----------------------------------------------------------EDLFILFFMEQNNRIFQTLSEVAVSAD-------PTLTAEHVRAMGLD--PQGDRGFLVDLLEIYGIDVMLVIDNPCCP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36090-1", "uniprot_id": "ANR2_YEAST", "id": "P36090-1", "name": "Uncharacterized protein ANR2", "aln": "----------------------------------------------------MNSGGEEPTIKPNVFN-------ITQLLNSNGEK----------------------PGIACIFLSKFDMKKGNIIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGIAYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYSSYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPYWTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVSDEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEESPEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFLIDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYNDLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNLPECLGNLC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*: : . .: :: :..:*: .** :.**:: *. . : ::*..:****:.:* *. .*.: * :* .* : :..::*. .:* *:*:: . :.: ::: * * * :: : . : :. :. : * . :. : : :* *: *** :**:.****: * .. . . * : :* :* :.: :*:* :..:** ** . *** *:*:*: * *:**: :. . .* .: : :.: :*. * * * : * *:: * .. : :: :* .:...::: * :* . : *::*.. :.** .: *: *: *: : : : : * * ", "identical_positions": 77, "similar_positions": 145, "identity": "12.9%" }, { "cls_id": "homologset.agr.SGD:S000001532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35216-1", "uniprot_id": "CENPA_MOUSE", "id": "O35216-1", "name": "Histone H3-like centromeric protein A", "aln": "-----------------------------------------------MGPRR---KPQTP----RRR-PS-------------------------------SPAPGPSR-QSSSVG--SQTLRR-RQKFMWLK--------------EIKTLQKSTDLLFRKKPFSMVVREICEKFS-RGVDFWWQAQALLALQEAAEAFLIHLFEDAYLLSLHAGRVTLFPKDIQLTRRIRGFEGGLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49450-1", "uniprot_id": "CENPA_HUMAN", "id": "P49450-1", "name": "Histone H3-like centromeric protein A", "aln": "-----------------------------------------------MGPRRRSRKPEAP----RRRSPSP------------------------------TPTPGPSR-RGPSLG--ASSHQHSRRRQGWLK--------------EIRKLQKSTHLLIRKLPFSRLAREICVKFT-RGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36012-1", "uniprot_id": "CENPA_YEAST", "id": "P36012-1", "name": "Histone H3-like centromeric protein CSE4", "aln": "-------MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V6Q2-1", "uniprot_id": "CID_DROME", "id": "Q9V6Q2-1", "name": "Histone H3-like centromeric protein cid", "aln": "MPRHSRAKRAPRPSANNSKSPNDDDTAFRSPEPEDGTDYGLEFTTSQLTLQDNNRRSSTLRRDAGRRQPAARD--SSTSGEEEDQENRYPTTRSPQTRRMTVQQESKTRAAGPVAAQNQTRRRKAANPMSRAKRMDR----------EIRRLQHHPGTLIPKLPFSRLVREFIVKYS-DDEPLRVTEGALLAMQESCEMYLTQRLADSYMLTKHRNRVTLEVRDMALMAYICDRGRQF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** : . * . :: . * **: *: . *: * **: :.:*. ::: . : *::*:**:.* :* : .: :*: * *:*: :*: * * . ", "identical_positions": 25, "similar_positions": 39, "identity": "10.46%" }, { "cls_id": "homologset.agr.SGD:S000001534", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC58-1", "uniprot_id": "DRAM1_MOUSE", "id": "Q9DC58-1", "name": "DNA damage-regulated autophagy modulator protein 1", "aln": "---------------MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFL---------------------------PYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNETC---YFSTPVFNLVSLALGLVGCIGMGIVANFQELAVPVVHDGGA---------------LLAFVCGVVYTLLQSIISYKSC------------------PQWNSLTTCHVRMAISAVSCAAVVPMIACASLIS--------ITKLEWNPKEKDYIYHVVSAICEWTVAFGFIFYFLTFIQDFQS---------------------------VTLRISTEINDDF---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N682-1", "uniprot_id": "DRAM1_HUMAN", "id": "Q8N682-1", "name": "DNA damage-regulated autophagy modulator protein 1", "aln": "---------------MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFL---------------------------PYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTC---YFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGA---------------LLAFVCGVVYTLLQSIISYKSC------------------PQWNSLSTCHIRMVISAVSCAAVIPMIVCASLIS--------ITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQS---------------------------VTLRISTEINGDI---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIL2-1", "uniprot_id": "A0AB32TIL2_DANRE", "id": "A0AB32TIL2-1", "name": "", "aln": "---------------MFWFMEGMCFLPTFLVIWSSSTFIISYIIALYRQDVDVVL---------------------------PYISDTGATPPESCVFGFMSTITAFAAFATMYAEYKFVERVHERT---GAVPPTLNKVSFGFGIFSCIGMCLVATFQETTVMEVHDIGA---------------LLFFICGVVYAVIQSVIGYRAF------------------PYGSSKFMCHLRTFFSTVAILAAIPTIACGFLVG--------TSKLHWDSNDKDYTRHIVSVACEWITTFSFVFFFLTYIQEFQQ---------------------------FTLKLTVNLKEYSGL-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9CR48-1", "uniprot_id": "DRAM2_MOUSE", "id": "Q9CR48-1", "name": "DNA damage-regulated autophagy modulator protein 2", "aln": "---------------MWWFQQGLSFLPSALVIWTFATFIFSYITAITLHHVDPAL---------------------------PYISDTGTIPPERCLFGVMLNIAAVLGIATMYVRYKQVHALNPEE---NLII-KLNKAGLVLGILSCLGLSLVANFQKSTLFIVHVCGA---------------VLAFSMGSFYMFVQTILSYQMQ------------------PKIHSKQVFWVRLLLVIWCGVSALSMMTCSSILYSSDFGPDVVQKLHWNPEDKGYVLHLVTTAAEWSMSFSFFGFFLTYIRDFQK---------------------------ITLRVEANLHGLTLYDTVPCPVNNERTPLLSRDFQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK09-1", "uniprot_id": "DRAM2_RAT", "id": "Q5BK09-1", "name": "DNA damage-regulated autophagy modulator protein 2", "aln": "---------------MWWFQQGLSFLPSALVIWTFATFIFSYITAITLHHVDPAL---------------------------PYISDTGTMPPERCLFGVMLNIAAVLGIATIYVRYKQVHALNPEE---NLII-KLNKAGLVLGILSCLGLSLVANFQKSALFIVHVCGA---------------VLAFSMGSFYMFVQTILSYQMQ------------------PKIHSKQVFWVRLLLVIWCGVSALSMMTCSSILYSSDFGADIVQKLHWNPEDKGYVLHIVTTAAEWSMSFSFFGFFLTYIRDFQK---------------------------ITLRVEANLHGLTLYDTVPCPVTNERTPLLSRDFQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UX65-1", "uniprot_id": "DRAM2_HUMAN", "id": "Q6UX65-1", "name": "DNA damage-regulated autophagy modulator protein 2", "aln": "---------------MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPAL---------------------------PYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEE---NVII-KLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGA---------------VLTFGMGSLYMFVQTILSYQMQ------------------PKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQK---------------------------ISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77262-1", "uniprot_id": "O77262_DROME", "id": "O77262-1", "name": "CWH43-like N-terminal domain-containing protein", "aln": "-------------------MSQVYLLPVLTFLIFQVTFLGTYIFAVLEGHVVPTV---------------------------PYISDAATYSPESCVFGQLINIGSVLLGITIYVRYRQVLQLYEHHPDLDGSVLRQNRLALWFGLVSCLGISFVGNFQETNVRIVHFIGA---------------FCCFGCGTLYFWMQALISYLIF------------------PMSGTRINAHLRLGMSVVCTILFILLAVTGVMSHILFKG---QNPRKWYPSDGGWYFHVVSSISEWVIATVFSFFILSFTNEFRD---------------------------VSLSHPQIALMSYSTTI-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R218-1", "uniprot_id": "T150B_MOUSE", "id": "Q8R218-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWNYLSLLPVILFLWAIAGIWIVFAIAVVNGSVDLNEGFPF-------------------------ISICGSYAPQSCIFGQVLNIGAALTVWICIVRHHQLRDWGVKT--------WQNQLILWSGILCALGTSIVGNFQDKNQKPTHLAGA---------------FLAFILGNLYFWLQFFLSWWVKG----------------LPQPGPHWIKSLRLSLCSLSTILIVAMIVLHALH-----------------------MRSASAICEWVVAMLLFMLFGFFAVDFSI---------------------------LRGCTLHLHPRLDSSLPQAPSGSPNIQMAQVL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEH7-1", "uniprot_id": "D3ZEH7_RAT", "id": "D3ZEH7-1", "name": "", "aln": "------------------MWNYLSLLPVILALWAIAGIWIVFAIAVVNGSVDLEKGFPF-------------------------ISNCGSYAPQSCIFGQILNTGAALAVWICIVRYHQLRDWGVKT--------WQNQLILWSGILCAVGTSIVGNFQEKNQKPTHLAGA---------------FLAFILGNLYFWLQFFLSWWMKG----------------LPQPGPHWIRLLRLSLCSLSTILIVTMIVLHSLH-----------------------MRSASAICEWTVAMLLFVLFGFFAVDFSS---------------------------FRGCTLHLQPHLDSSLQQAPSGSPNIQMAMVL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NC51-1", "uniprot_id": "T150B_HUMAN", "id": "A6NC51-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWGYLSLMPVFLAVWAISGVWIVFAIAVTNRTVDLSKGFPY-------------------------ISICGSFPPQSCIFSQVLNMGAALAAWICIVRYHQLRDWGVRR--------WPNQLILWTGLLCALGTSVVGNFQEKNQRPTHLAGA---------------FLAFILGNVYFWLQLLL-WRLKR----------------LPQPGAAWIGPLRLGLCSVCTILIVAMIVLHACS-----------------------LRSVSAACEWVVAMLLFALFGLLAVDFSA---------------------------LESCTLCVQPWPSLSPPPASPISLPVQL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PK2-1", "uniprot_id": "T150B_DANRE", "id": "Q32PK2-1", "name": "Modulator of macroautophagy TMEM150B", "aln": "------------------MWAWA-LLPVFLAVFGTVGLWAVYAIAVSNNSVNITIEFPY-------------------------ISTCGAYTPQSCLFAQICNICCVLALWIVVIRFQQIRDLGRSS--------HLNTAGLVLGFISSIGISILGNFQQTIIQEVHLLGA---------------LMAFFLGLAYFWIQAFITYFSP------------------PSRDNKWLVPVRFVLCSQCTCMVICMFVLHSTG-----------------------FRSAAAICEWILVMCFFALFGVFAAEFRH---------------------------IDFHKLTVQ-KEGLKVANNDNVVWTVQDVQ----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91WN2-1", "uniprot_id": "T150A_MOUSE", "id": "Q91WN2-1", "name": "Transmembrane protein 150A", "aln": "-------------------MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNESCSPDPAEQGGPKSCCTLDDVPLISKCGTYPPESCLFSLIGNMGAVMVALICLLRYGQLLEQSRHS--------WINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGT---------------GVAFTAGLLFVCLHCVLFYHGAT----------------TPLDMAMAYLRSVLAVIAFITLVLSGVFFLHESSQ----------------------LQHGAALCEWVFVLDILIFYGTFSYEFGT---------------------------ISSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZE9-1", "uniprot_id": "T150A_RAT", "id": "Q9QZE9-1", "name": "Transmembrane protein 150A", "aln": "-------------------MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNDSCSPDPAEQGGPKTCCTLDDVPLISKCGTYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQNRHS--------WINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGA---------------GVAFPAGLLFVCLHCVLFYHGAT----------------TPLDMAMAYLRSVLAVIAFVTLVLSGVFFLHESSE----------------------LQHGAALCEWVFVLDILIFYGTFSYEFGA---------------------------VSSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TG1-1", "uniprot_id": "T150A_HUMAN", "id": "Q86TG1-1", "name": "Transmembrane protein 150A", "aln": "-------------------MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHS--------WVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGA---------------GVAFPAGLLFVCLHCALSYQGAT----------------APLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQ----------------------LQHGAALCEWVCVIDILIFYGTFSYEFGA---------------------------VSSDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C8S3-1", "uniprot_id": "T150C_MOUSE", "id": "Q8C8S3-1", "name": "Transmembrane protein 150C", "aln": "--------------MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGA----------------KHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNP--------WLNISGLAALCLASFGMTLLGNFQLTNDEEIHNVGT---------------SLTFGFGTLTCWIQAALTLKVN------------------IKNEGRRAGIPRVILSAVITLCVVLYFILMAQD-----------------------IHMYAARVQWGLVMCFLAYFGTLAVEFRH---------------------------YRYEIVCSEYQENFLSFSESLSEASEYQTDQV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFH9-1", "uniprot_id": "T150C_RAT", "id": "B5DFH9-1", "name": "Transmembrane protein 150C", "aln": "--------------MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGV----------------KHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNP--------WLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGT---------------SLTFGFGTLTCWIQAALTLKVN------------------IKNEGRRAGIPRVILSAVITLCVVLYFILMAQD-----------------------IHMYAARVQWGLVMCFLAYFGTLAVEFRH---------------------------YRYEIVCSEYQENFLSFSESLSEASEYQTDQV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B9EJG8-1", "uniprot_id": "T150C_HUMAN", "id": "B9EJG8-1", "name": "Transmembrane protein 150C", "aln": "--------------MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAERKPGV----------------KHAPYISIAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNP--------WLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGT---------------SLTFGFGTLTCWIQAALTLKVN------------------IKNEGRRVGIPRVILSASITLCVVLYFILMAQS-----------------------IHMYAARVQWGLVMCFLSYFGTFAVEFRH---------------------------YRYEIVCSEYQENFLSFSESLSEASEYQTDQV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PS77-1", "uniprot_id": "A0A8M9PS77_DANRE", "id": "A0A8M9PS77-1", "name": "", "aln": "----------------MRKCSPWMFLPIMFSFFTAAGLWVVYFIAVEDEKITPLSSEYKRSES----------------KSPPYISIAGNAPPASCVFSQVMNMAAFVGFILGVLRYLQLKPRVHKP--------WLNIGSLVALSLACFGMTLVGNFQLSNDEELHNIGT---------------SMTFGLGTLFCWVQSFMTLKVN------------------LRNEGKRAGIPRFLLSGAVTSCMLLYFALMAQR-----------------------LHMHAARAQWALVMFFLTYLGTFAIEFRH---------------------------YHFEIVCSDDQDPPLSLSESFSEVSEYQSDQL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35735-1", "uniprot_id": "SFK1_YEAST", "id": "P35735-1", "name": "Protein SFK1", "aln": "MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFMHSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSISDSTSYAEKLHSGKYLMPPYYTKDE-------RNLIFAAFVLGSIGELALLFSSIFSTALYHRVHIAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDELPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFG------------------AINDRSKSACFEWLLAFWFGIIFMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATETASSNIYNNSSSNESIQVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : :. . . . .. : . . . *. * . * * :: . : : :* : :* ", "identical_positions": 6, "similar_positions": 25, "identity": "1.59%" }, { "cls_id": "homologset.agr.SGD:S000001538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VT4-1", "uniprot_id": "CBR4_MOUSE", "id": "Q91VT4-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "--MDKVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAG---ELGG-NHLAFRCDVAK--------------------------EQDVQSTFQEMEKHLGP-----VNFLVNAAGINRDSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQ------------GGSIVNVGSIIG--LKGNVGQSAYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGFIR-TDMTRHL---KEEHFKKNIPLGRFGETLEVAHAVVFLLESPYITGHVLIVDGGLQLTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS56-1", "uniprot_id": "CBR4_RAT", "id": "Q7TS56-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "--MDKVCAVFGGSRGIGKAVAQLMAQKGYRLAIVARNLEVAKATAS---ELGG-IHLAFRCNIAK--------------------------EGDVHSTFEEMEKHLGP-----VNFLVNAAGINRDSLLVRTKTEDMLSQLHTNLLGTMLTCRAAMRTMIQQ------------GGSIVNVGSIIG--LKGNVGQAAYSATKGGLIGFSRSLAKEVARKKIRVNVVAPGFIH-TDMTKHL---KEEHFKKNIPLGRFGEALEVAHAVVFLLESPYITGHVLIVDGGLQLTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4T8-1", "uniprot_id": "CBR4_HUMAN", "id": "Q8N4T8-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "--MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG---DLGG-DHLAFSCDVAK--------------------------EHDVQNTFEELEKHLGR-----VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ-----------GGSIVNVGSIVG--LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH-TDMTKDL---KEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0H7-1", "uniprot_id": "CBR4_DANRE", "id": "Q6P0H7-1", "name": "Carbonyl reductase family member 4", "aln": "--MSRLAVVFGGSRGIGRAASKLLAQRGHRIVLLSRNKEAAQSTAQ---SLPGENHLGLSCDVSK--------------------------EEEVQKAFETINKTCGT-----VGFLVNAAGINRDALLLRSKSEDMLSVLHTNLLGSMLTCKAAVRNMLSH------------GGAIVNIGSVVG--VKGNAGQCVYSASKAGLEGFTRSLAKEVASRNIRVNLVAPGLIH-TDMTAGL---AEEAAVRTIPLGRFGEPAEVAQAMLFLLESPYITGQILLVDGGLQLLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35731-1", "uniprot_id": "FABG_YEAST", "id": "P35731-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * *.:****:* .: : ::* ::. . * : :* .* . * :: : . . *: :* . *.:*:*.**:.::.* :*:.:.:: . ::.*::..: . .:: *:. :***:.*:: * ..***:*..* *:. ** *: ::** ::**::: *** * :* :.* . . . *:*. : * . . : ", "identical_positions": 50, "similar_positions": 89, "identity": "17.18%" }, { "cls_id": "homologset.agr.SGD:S000001539", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63028-1", "uniprot_id": "TCTP_MOUSE", "id": "P63028-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDDSLIG-GNASAEGPEGEGTESTVVTGVDIVMNHHLQET-SF-TKEAYKKYIKDYMKSLKGKLEEQKPERVKPFMTGAAEQIKHILANFNNYQFFIGENMNPDGMVALLDYRE--DGVTPFMIFFKDGLEMEKC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63029-1", "uniprot_id": "TCTP_RAT", "id": "P63029-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDDSLIG-GNASAEGPEGEGTESTVVTGVDIVMNHHLQET-SF-TKEAYKKYIKDYMKSLKGKLEEQKPERVKPFMTGAAEQIKHILANFNNYQFFIGENMNPDGMVALLDYRE--DGVTPFMIFFKDGLEMEKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GKA0-1", "uniprot_id": "A0A8I6GKA0_RAT", "id": "A0A8I6GKA0-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDDSLIG-GNASAEGPEGEGTKSTVVTGVDIVMNHHLQET-SF-TKEAYKKYIKDYMKSLKGKLEEQKPERVKPCMTGAADQIKHILANFNNYQFFIGENMNPDGMVALLDYRE--DGVTPFMIFFKDGLEMEKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AN27-1", "uniprot_id": "A0A8I6AN27_RAT", "id": "A0A8I6AN27-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDFISLDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDDSLIG-GNASAEGPEGEGTESTVVTRVDIVMNHHLQET-SF-TKEAYRKYIKDYMKSLKDKLEEQKPERVKPFMTGAAEEIKHILANFNNYQFFIGEKMNPDGMLALLDYRE--DGGTPFMIFFKDVL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ALE5-1", "uniprot_id": "A0A8I6ALE5_RAT", "id": "A0A8I6ALE5-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDLISHDELFSNIYKIREIADRPCLEVEGKMVSRTEGAIDDSLIG-GNAPAEGPEGGRTESTVVTGVDIVLNHHLQET-SF-TKEAYKKYIKDYMKSLKGKLEEQKPERVKPFMTGAAEKIKRILANFNNYQFFIGENMNPDGMVALLEYPE--DGVTPFMIFFKDGLEMEKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13693-1", "uniprot_id": "TCTP_HUMAN", "id": "P13693-1", "name": "Translationally-controlled tumor protein", "aln": "MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIG-GNASAEGPEGEGTESTVITGVDIVMNHHLQET-SF-TKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYRE--DGVTPYMIFFKDGLEMEKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HAU6-1", "uniprot_id": "TCTP8_HUMAN", "id": "Q9HAU6-1", "name": "Putative translationally-controlled tumor protein-like protein TPT1P8", "aln": "MIIFQDLISHNEMFSDIYKIWEITNGLCLEVEQKMLSKTTGNTDDSLIG-RNSSSESTEDEVTESTIITSVDIVTNHHLQES-IF-TKEAYKKYIKDYMKSINEKLEEQRPERVKLFITG----------------------MKNKSSTSLLIFK------TTSSLLVKT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGK4-1", "uniprot_id": "TCTP_DANRE", "id": "Q9DGK4-1", "name": "Translationally-controlled tumor protein homolog", "aln": "MIIYKDIITGDEMFSDIYKIKESENGMMLEVEGKMITRAEGDIDDALIG-GNASAEVAD-EGCDSTSVSGVDIVLNHKLQET-SY-DKKSYTAYIKDYMKAVKAKLQESAPNRVDPFMANAPAEVKKILGNIKNFQFFTGESMNPDGMIGLLDFRE--DGVTPYMIFFKDGLEIEKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35691-1", "uniprot_id": "TCTP_YEAST", "id": "P35691-1", "name": "Translationally-controlled tumor protein homolog", "aln": "MIIYKDIFSNDELLSDAYDAK-LVDDVIYEADCAMVNVGG---DNIDIG-ANPSAEGGD-DDVEEGAEMVNNVVHSFRLQQT-AF-DKKSFLTYIKGYMKAVKAKLQETNPEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYRE-DG-TTPFVAIWKHGIVEEKI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VGS2-1", "uniprot_id": "TCTP_DROME", "id": "Q9VGS2-1", "name": "Translationally-controlled tumor protein homolog", "aln": "MKIYKDIITGDEMFADTYKMK-LVDDVIYEVYGKLITRQG---DDIKLEGANASAEEAD-EGTDITSESGVDVVLNHRLTECFAFGDKKSYTLYLKDYMKKVLAKLEEKSPDQVDIFKTNMNKAMKDILGRFKELQFFTGESMDCDGMVALVEYREINGDSVPVLMFFKHGLEEEKC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::*::: :*:::: *. : *. ::. *: : *..:* : . ::* ..:* : : *::: *:*.*** : **:* *:.* . *. .. :: : .. : * ", "identical_positions": 24, "similar_positions": 49, "identity": "13.56%" }, { "cls_id": "homologset.agr.SGD:S000001540", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBL6-1", "uniprot_id": "D3ZBL6_RAT", "id": "D3ZBL6-1", "name": "", "aln": "----------------------------------MAAAGSLERSFVELSGAERERPRHFREFTVCDLGTANAAFGAVKYSESAGGFYYVESGKLFSITRNRFIHWKTSGDTLELVEESLDLNLLNNAVRLKFQNYSLLPGGVHVSETQNHVIILILTNHTVHRLILPHPSRMYRSELVTESQMQSIFTDIGKVDFKDPCNYQLIPTVPG-LSPSSTTSAAWLSSDGEALFALPSASGGIFVLKLPPYDIPGIASVVELKQSSVMQRLLTGWMPTAIRGDHGPSDRALSLAVHCVEHDAFIFALCQDHKLRMWSYKDQMCLMVADMLEYVPVNK-DLRLTAGTGHKLRLAYSPSMGLYLGIYMHAPKRGQFCIFQLVSTESSRYSLDHISSLFTS-QETLVDFALTSTDIWALWHDAENQTIVKYINFEHNVAGQWNPVFMQSLPEEEIVIRDD-QDPREMYLRSLFTPGQFINAALCKALQIFCRG--TERNLDLSWSELKKEITLAVENEVRCWLQGSVTEYEFSQDEFRTLQQEFWCKFYACCLQYQEALSHPLALHLNPLTNMVCLLKKGY-LSFLVPSSLVDHLYLL--PDEHLLTEDETTISDDADVARDVLCLIKCLRMIGESVTMDMAVLMETSCYNLQSPEKAAEHILEDLITID------VENVMEDICSKLQEIRNPVHAIGLLIREMDYETEVEMEKGFDPAQPLNVRMNLSQLYGSSTAGYIVCRGVYKIASTRFLICRDLLILQQLLTRLGD-AVILGAGQLFQAQQDLLHRTAPLLLSYYLIKWSSQCLATDVPVDTLESNLQHLSVLELTDSGALMANKLVSS----PQTIMELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMVTAVTGYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQ-LLHPWCQVNVGSCRFMLGRCYLVTGEVQKALECFCQAASEVGKEEFLDRLIR-----------------TEDGEIVSTPKLQYYDKVLRLLDVVGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLGGLEKQGNCYLAAINCLRLIRPEYAWIVQPASGAVSDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLARHDPSAIAIAGSSSAKEMSTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQGEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQN-NLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGEN-SANSHNIILSQKILDKLEDYQQKVDKATRDLLYRRDL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0W3-1", "uniprot_id": "NU160_MOUSE", "id": "Q9Z0W3-1", "name": "Nuclear pore complex protein Nup160", "aln": "----------------------------------MAAAGSLERSFVELSGAERERPRHFREFTVCDIGTASAAFGTVKYSESAGGFYYVESGKLFSITRNRFIHWKTSGDTLELVEESLDLNLLNNAVRLKFQNYNILPGGVHVSETQNHVIILILTNQTVHRLILPHPSRMYRSELVTESQMQSIFTDIGKVDFRDPCNSQLIPSVPG-LSPGSTTSAAWLSSDGEALFALPSASGGIFVLKLPPYDVPGIASVVELKQSSVMQRLLTGWMPTAIRGDHGPSDRALSLAVHCVEHDAFIFALCQDHKLRMWSYKDQMCLMVADMLEYVPVNK-DLRLTAGTGHKLRLAYSPSMGLYLGIYMHAPKRGQFCVFQLVSTENNRYSLDHISSLFTS-QETLVDFALTSTDIWALWHDAENQTIVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDD-QDPREMYLRSLFTPGHFINAALCKALQIFCRG--TERNLDLSWNELKKEITLAVENEL----QGSVTEYEFSQDEFRTLQQEFWCKFYACVLQYQEALSHPLALHLNPVTNMVCLLKKGY-LSFLVPSSLVDHLYLL--PDEHLLTEDETTISDDADVARDVLCLIKCLRMIGESVTMDMAVLMETSCYNLQSPEKAAEHILEDLITID------VENVMEDICSKLQEIRNPVHAIGLLIREMDYETEVEMEKGFDPAQPLNVRMNLSQLYGSSTAGYIVCRGVYKIASTRFLICRDLLILQQLLTRLGD-AVILGAGQLFQAQQDLLHRTAPLLLSYYLIKWASQCLATDVPVDTLESNLQHLSVLELTDSGALMANKLVSS----PQTIMELFFQEVARKQIISHLFSQPKAPLSQTGLNWPEMITAVTGYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQ-LLHPWCQVNVGSCRFMLGRCYLVTGEVQKALECFCQAASEVGKEEFLDRLIR-----------------SEDGEIVSTPKLQYYDKVLRLLDVVGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAAINCLRLIRPEYAWIVQPASGAVSDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKEYSLARIRLTLARHDPSVIAIAGSSSAKEMSALLVQAGLFDTAISLCQTFTLPLTPVFEGLAFKCIKLQFGGEAAQGEAWSWLATNQLSSVITTKESSATDEAWRLLSTYLERYKVQN-NLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGEN-SANSHNIILSQKILDKLEDYQQKVDKATRDLLYRRDL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12769-1", "uniprot_id": "NU160_HUMAN", "id": "Q12769-1", "name": "Nuclear pore complex protein Nup160", "aln": "MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPG-ISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKK-DLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTS-QETLIDFALTSTDIWALWHDAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDD-QDPREMYLQSLFTPGQFTNEALCKALQIFCRG--TERNLDLSWSELKKEVTLAVENEL----QGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHLNPHTNMVCLLKKGY-LSFLIPSSLVDHLYLL--PYENLLTEDETTISDDVDIARDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITID------VENVMEDICSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLGD-AVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSS----PQTIVELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQ-LLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIR-----------------SEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQN-NLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGEN-SANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TC69-1", "uniprot_id": "A0AB32TC69_DANRE", "id": "A0AB32TC69-1", "name": "", "aln": "------------------------------------MAGVLERSYIEICGFERETVSRFRQITLN-LGGVGVSSGGVKYADSAGGFSYEDSGKLLSVTSNRFIHWATSGDTVQLVEQSLDTNLLNNAVRLRIPQCLLLPGGVSIQETLNNVIILIVTSQSVHRLVLPHPTRMYRSDLVTELQMQSIFTDIGKLNLNGPAHSYVLPFTQGPHSSAPSTSAAWISHQGEALFALASPSGGIAVVTLPAHDQDGSVSILELKQSSMMQR-LAGWMPTAIRGDQSMSDMAVSLAVHQLEDDTFIFTLCQDHKLRMWSLKHQMCVLVTDMLEFLPVGRGEVKASPAQAHKLRLFFSSSTGLCVAVYLSVPKRSQFCVLQLVANESSRYSLDHISTLFST-QETLVDFVLTATDIWALWLDNDNQTVAKYISFEHNTTGMWNQVFVQPSPEEEVHIGED-QDPREIYLDVLFSPLRFTASAIIKALQIYKRG--PERYSDLSWEELKKEVTVTVESEL----QGSVTEYEFCQEDYRLLQVEFWSKFYACCLQYQDVLSTPLALHVSPSTGMICVLKKGF-VSFLLPCFAVDHLYLS--SDEYLFSEEETPIAEDAEVSRDVLQLVQCLRLVNESLPEEMAYEMDKALDELLSPEKVSEKILESLLAND------TGNVIGDIANKLQDIYNPIAAMNMLLRELDLETDAEPDAR-HAGQSLRVRISLSQLYGSSVAASLICQAVCQTAMTRTLLCRDLLILQQLYLRIGENAFISGGPQLLQLQQDLIPRCSNLLCTYHLLKQMSLTLSSSVPLDILNADLQHLSVLELSDSSTPASSRSVLN----PQTVVELFYQSVARKTIMSQIFSQQDMESDQSVLHWPQMISSVLTLLCQALWPSNPSFLFPECLMGNCQYAQLQEYVR-LVGPWCQVNVGSYRFVLGQCYLASGEGQKALQCFQEAATEVNKEEFLMKLTG-----------------SDE-ETATAPRLLYYNKVLRLLEDIGLPELVIELATLAVSEATDDKRSQAALWTRIFKHHLDLGHNSQAYEALTQNPDSSRQLDCLRQLVVVLCERAQLRDLVQFTYVNLHDEVVSIIESRARAVDLMTHNYYELLYAFHINRHNYRKAGTVMFEYGMRLGREVRTLRGLQKQVNCYLAALNCLRLVSPDYAWIVQPSSGAAYERPGASPKRTHDGEFAESPVNQQIDILELKDLEKEYVLARSRLTLAQQDPPSAAIAGGASSQEMVALLVQAGLFDTSLTLCQTFNLPLTPVFEGLTFKCIKLQYKGDQDQTEVWNWLAANQLPTVITTKETSATDEAWRLLAHYLEKFPSHN-APHHRCVINKLLSHGVPAPDWLINAYKEVDAAALLRLYLNYDLLEAAAELVLEFVDALLGKGHQYFGIERPLSATAALVWLPYTSIDQLLRNLSES-QINEK---MYRSLQDKLAEYHRLVDQSSRHRLMAR------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKJ3-1", "uniprot_id": "NU160_DROME", "id": "Q9VKJ3-1", "name": "Nuclear pore complex protein Nup160 homolog", "aln": "------------------------------------MPTSKLQANMSYREVIPRNLSPAEWIEVKINTGTQSTLQDLKTFETSGGYCYKNTKNVQ--TRNRFIYWRTYQDVLELSEVSLDISLQRNHLRLRFTDSAVLN--VSLTEQGTSVTLLVVTVSSVHRYVFPLKVAGQEGGAASP---EDLLSQSIFYDVNDKINDPSTYYVTDGFGTMPNAAVSYLTQDSQSAYFAVAYQSKLLLHVMKCS--TGHTITHEIKEPKLMPWFLSNLKG-ALTGRSETLEAATSMAFSEIGGEIFILVLYRNNELRLWSVDNLQTVASINCSTELGQDS-------AAQGPQNSQLRKISDQNFCLFLSHNSRAEFICVSIMPDADDASVINLVQNMVPAPQTDLVDFDATSSHIWALWSNAEGDFHVSAAYFASNNAIKWVSAALEPPPDRYCLTMEQGVDPRETYCSYIFHPGRFDRNVIAKALYMFRRVNLQFDVKQLSMSVLKEQVCQAVEDEI----QNELKDFVVTDEEYLEISTRLWDRFYSCCEQYHIKLSEPTGLAVLGGMDAVCLVRRQS-FALLRPCEVLEHLLLIGEHNDEVATYVAPLFRNDPEMAKGFVELMNVVTLLDKLISEDIKIELDKQLYQRESPVEVISKLVARISMIDDNGPILPSNCVRQIQQKLQNIPNLEPALEMLLDVLCMIDPDEPPHDYSLSTRFLQ--SSGALMGSEYGLSILSETVKQMAMIRFSVCRNLLVLQYMAYGQNE------------MESENVLTNLNYLNSYYTLVWIAETPISSSTPAGFEASIQRLSRAQLFSGYNRPYSSHLKHNGNDQTTLLRLFLESKGLFSALTMLLKHDSLSLDSEQLNLRQSLLQLVGYINKMLWPGSPIYVFPEWLFGTCHHIIVQDYVR-ILSNWCSVQKHARRFMLAVSLLDCGEAHKAVHLFHEAESGIVEDDFLFEHVLKNTPLYGKLQNSVSRGDTISPEDTKLAIVHYYLKVIQLFEQHSALDYIIQLADMAIRVLQPDDPQLPMFQSIVFNNHLQLGHYVEAYTALVNNADISRRKDCLRQLVITLFQNKCLPLLMQFSYIGLQDEFESIVESRARSMSIDQNEVYNFLYAFHTNKGNMRKASTVMYEQAMRFQVDSDAPNALEKRCSSLLICLNCLHLVDSRYRWIAKPVLGDEQVITIDQDNDDGEPKCDEDKRGQEVVVLELADIRRELVHAEALRELSFYRKDTAAYER-ATPEELSYLLASSGLYTAALKLSRGHSFSVLPIFESLTSACVAATE---DKSSDAWNWLQNNDMADLPHR--SNAADMAWTLLQKLVVDNEAKDSTLIRKSVVQRLLGLNAFLPQWLINSYKLSHSRELLHLLVKHNRLLEAADLGCEIIAGMLGAGSEYFEFKHAVNIANPQLCFPISTIDLLLHGLKINGKDDLDYEMAYFKLEEEVQRYIETIKRTTDDKMSMAVLQMRTDLQEER", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35729-1", "uniprot_id": "NU120_YEAST", "id": "P35729-1", "name": "Nucleoporin NUP120", "aln": "-----------------------------------MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLN--GEWFHLQNPYDFTVRVPHFLFYVSPQ-------FSVVFLEDGG----------------LLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYD------SVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYN------NTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIES-VNKSLVDLQSEHDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNED----------------------EEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYN---------------MHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITG-----ELPDSMTTVEK---------FTDIFKNCLENQFEITNLKILFDELN---------------SFDIPVVLNDLINNQMKPGIFWK-KDFISAIKFDGFTSIISLESLHQ---------------------------LLSIHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQD----KCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTF-------FRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGN---------------------------------------------------------FDQSYEIFQLHDYPEAINDKLPTFLEDLKSENYHGDSIWKDLLCTFTVPYRHSAFYYQLS------------------------------------------------------------LLFDRNNSQEFALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLR-----------------LGHECLSDTVRTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQN-------------------------------------LRSGDWECFKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRK-RKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDLRDELRGL-------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : : : ..:* : * .*. : :.::: : : . : :: : : . . : :. :. :: . : * : : . *: : . *: : : :::.* :: .*::*. : : . : : ... * :: .. ..: . . : .* : : . : . : :: . . :. : . . : : : : . *.:: ...* . .: : : : :. . .: : : : :: ::: .. . .. :. : . . :. :: :. : : .: : : . :* .: : : :*: : : * ... :. . : : .:: *: : * :: : . : : :* . : .:: :. . ::. . *: : : * . :: . : :: ::. : : : .*::. : *: : : .::: . : : : : : : . :: . : * * :*: : : *. : * .:: :*: * : :::. : . . : :* *: . : : : :* . * : : *:: : : :. *:: * . . :*::*. * * ", "identical_positions": 41, "similar_positions": 270, "identity": "2.75%" }, { "cls_id": "homologset.agr.SGD:S000001541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZM7-1", "uniprot_id": "T2AG_MOUSE", "id": "Q80ZM7-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08950-1", "uniprot_id": "T2AG_RAT", "id": "O08950-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52657-1", "uniprot_id": "T2AG_HUMAN", "id": "P52657-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINAALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52656-1", "uniprot_id": "T2AG_DROME", "id": "P52656-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MS----YQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLN------DVEFREV--------HEIVKVDKVKIVACDGK-SGEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B9-1", "uniprot_id": "T2AH_DROME", "id": "Q9W5B9-1", "name": "Transcription initiation factor IIA subunit 2-2", "aln": "MN----YQHYRATTLGRTLQDTLDEMMERGDITKKIANLVLLRYDKSISTALKDHGTSNMSFTAERLETFRCCDNVWTLILK------DAEFRED--------QHSLKVDVVKIVACLGTDNGNE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32774-1", "uniprot_id": "T2AG_YEAST", "id": "P32774-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLTVK-GNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKSE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: ** :*:*.:* ::** ::. * :* ** :** : :* :. .:.. *:*: **:***:::: : ..*: :.** ::**** .. . ", "identical_positions": 30, "similar_positions": 38, "identity": "23.44%" }, { "cls_id": "homologset.agr.SGD:S000001542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V953-1", "uniprot_id": "G3V953_RAT", "id": "G3V953-1", "name": "E3 ubiquitin-protein ligase RBBP6", "aln": "-MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKL-KAADSDLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPVMG-TTKAIDDSSASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKTLVGPP-----------------PPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPISAPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSAHSTPSISSLTSNPSSLAPSVPGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKLLPAAALASEHSKGASSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINAARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANISTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPTKRNVPQGETEREYFNRYREVPPPYDIKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAVGAQPRPSANREDFSPERLLPLNIRNSPFTRGRREDYVAGQSHRNRNLGGNYPEKISTRDSHNPKDNPKSKEKESENVPGDGKGNKHKKHRKRRKGEESESFLNPELLETSRKSRESSGIDETKTDALFVLPSRDDATPVRDEPMDAESITFKSVSEKDKREKDKPKVKSDKTKRKSDGSATAKKENVLKPSKGPQDKVDGDREKSPRSEPPLKKAKEEATKVDSVKPSSS-QKDEKVTGTPRKAHSKSAKEHQEAKPVKEEKAKKDCSKDIKSEKPASKDEKAKKP-EKNKLLESKGEKRKRKTEEKSVD--FESSSMKISKVEGTEIVKPSPKRKMEGDVEKLERTPEKDKSASSTTPAKKIKLNRETGKKIGNAENPSTTKEPSEKLESTSNKIKQEKVKGKARRKVAGTEGPSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDDVRTTQPIQSVGKPSSIIKNVTTKPSATVKCTEKENEQSEKIQKLTKEVSHEVIQHELRSSKGSVSSEKGRAKDRDHSASEKDNPDKRKTSIQPDKESTVDRLSEQGHFKNLSQSSKETRTSEKHESVRGSSNKDFTPGRDKKTDYDSRDYSSSKRRDERSELTRRKDSPPRSKDSLSGQKSKLREEKDLPKKGT-ELKKSNSSPPRDKKPHDHKASYETKRSCEETKSVDKNAGKEREKHAAEASRNGKESSGSKLPSIPNPPDPPMEKELAAGQIEKSTIKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEEAVASVSKDLKEKATEKATESLNVATASQPGADRSQSQSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKDKKKHKKHKKHKKHKKHAGVDGDVEKSQKHKHKKKKAKKNKDKEKEK--DDQKVKSVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97868-1", "uniprot_id": "RBBP6_MOUSE", "id": "P97868-1", "name": "E3 ubiquitin-protein ligase RBBP6", "aln": "-MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKL-KAADSDLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPVMG-TTKAIDDASASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKTLVGPP-----------------PPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPVPPPRPLMQRNLQPLMRSPISRQQDPLMIPVTSSSAHSAPSISSLTSNPSALAPSVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKLLPAAALTSEHSKGASSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINAARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANISTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPTKRNVPQGETEREYFNRYREVPPPYDIKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAVGAQPRPSANREDFSPERLLPLNIRNSPFTRGRREDYAAGQSHRNRNLGGNYPEKLSTRDSHNAKDNPKSKEKESENVPGDGKGNKHKKHRKRRKGEESESFLNPELLETSRKCRESSGIDETKTDTLFVLPSRDDATPVRDEPMDAESITFKSVSDKDKREKDKPKVKSDKTKRKSDGSATAKKDNVLKPSKGPQEKVDGDREKSPRSEPPLKKAKEEATKIDSVKPSSSSQKDEKVTGTPRKAHSKSAKEHQEAKPAKDEKVKKDCSKDIKSEKPASKDEKAKKP-EKNKLLDSKGEKRKRKTEEKSVDKDFESSSMKISKVEGTEIVKPSPKRKMEGDVEKLERTPEKDKIASSTTPAKKIKLNRETGKKIGNAENASTTKEPSEKLESTSSKIKQEKVKGKAKRKVAGSEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEED-VKTTQPIQSVGKPSSIIKNVTTKPSATAKYTEKESEQPEKLQKLPKEASHELMQHELRSSKGSASSEKGRAKDREHSGSEKDNPDKRKSGAQPDKESTVDRLSEQGHFKTLSQSSKETRTSEKHESVRGSSNKDFTPGRDKKVDYDSRDYSSSKRRDERGELARRKDSPPRGKESLSGQKSKLREERDLPKKGA-ESKKSNSSPPRDKKPHDHKAPYETKRPCEETKPVDKNSGKEREKHAAEA-RNGKESSGGKLPCIPNPPDPPMEKELAAGQVEKSAVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEEAVASISKDLKEKTTEKAKESLTVATASQPGADRSQSQSSPSVSPSRSHSPSGSQTRSHSSSASSAGSQDSKKKKKKKEKKKHKKHKKHKKHKKHAGADGDVEKSQKHKHKKKKAKKNKDKEKEK--DDQKVRSVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6E9-1", "uniprot_id": "RBBP6_HUMAN", "id": "Q7Z6E9-1", "name": "E3 ubiquitin-protein ligase RBBP6", "aln": "-MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKL-KAADCDLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMA-TTKAIDDSSASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLG-PP-----------------PPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDK-ISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEED-VKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEA-RNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GS96-1", "uniprot_id": "A0AC58GS96_DANRE", "id": "A0AC58GS96-1", "name": "", "aln": "-MSCVHYRFQSRLTYDSLQFDGLNITVGELKRQIMRRERL-KFCQ--LKISKAQTDEEYTDDDALIPKNTSVIIRRVPAAGLKSSNRRFVGHQAGLSAK-SSQTGD--SSLLSLEQLLKTENLAEAKASEEDKLKAVMYQSSLCYYSSSEAMTLLGLLP-----------------PN-YVCFHCGIPGHHIRHCPSKGGSSSAPLKRIRRSTGIPRSFLLEVDDPNRKGVMMDGSGKYVIPIIDAEAYAAEKKKRPSFSCQTKPLPS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVQDARGKRSRSPSPPETHGDQKRPRH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TPM3-1", "uniprot_id": "A0AB32TPM3_DANRE", "id": "A0AB32TPM3-1", "name": "", "aln": "-MSCVHYRFQSRLTYDSLQFEGLNITVGELKRQIMRRERL-KFCQ--LKISKAQTDEEYTDDDALIPKNTSVIIRRVPAAGLKSSNRRFVGHQAGPSAK-SSQTGD--SSLLSLEQLLKTENLAEAKASEEDKLKAVMYQSSLCYYSSSEAMTLLGLLP-----------------PN-YVCFHCGIPGHHIRHCPSKGGSSSASQKRIRRSTGIPRSFLLEVDDPNRKGVMMDGSGKYVIPIIDAEAYAAEKKKRPSFSCQTKPLPS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVQDARGKRSRSPSSPETHGDQKRPRH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GS50-1", "uniprot_id": "A0AC58GS50_DANRE", "id": "A0AC58GS50-1", "name": "", "aln": "-MSCVHYRFQSRLTYDSLQFEGLNITVGELKRQIMRRERL-KFCQ--LKISKAQTDEEYTDDDALIPKNTSVIIRRVPAAGLKSSNRRFVGHQAGPSAK-SSQTGD--SSLLSLEQLLKTENLAEAKASEEDKLKAVMYQSSLCYYSSSEAMTLLGLLP-----------------PN-YVCFHCGIPGHHIRHCPSKGGSSSAPHKRIRRSTGIPRSFLLEVDDPNRKGVMMDGSGKYVIPIIDAEAYAAEKKKRPSFSCQTKPLSS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVQDAGGKRSRSPSSPEMHGDQKRPRH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B3Y2-1", "uniprot_id": "A0A8M3B3Y2_DANRE", "id": "A0A8M3B3Y2-1", "name": "", "aln": "-MSCVHYRFQSRLTHDSLQFEGLNITVGELKRQIMRRERL-KFCQ--LKISKAQTDEEYTDDDALIPKNTSVIIRRVPAAGLKSSNRRFVGHQAGPSAK-SSQTGD--SSLLSLEQLLKTENLAEAQASEEDKLKAVMYQSSLCYYSSSEAMTLLGLLP-----------------PN-YVCFHCGIPGHHIRHCPSKGGSSSAPHKRIRRSTGIPRSFLLEVDDPNRKGVMMDGSGKYVIPIIDAEAYAAEKKKRPSFSCQTKPLSS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVQDARGKRSRSPSSPEMHGDQKRPRH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GAL1-1", "uniprot_id": "A0AC58GAL1_DANRE", "id": "A0AC58GAL1-1", "name": "", "aln": "-MSCVHYRFQSRLTYDSLQFEGLNISAGELKRQIMRSKRL-KFCQ--LKISNAQTDEEYT-DDALIPKNTSVIIRRIPAAGLKSSNRRFVGHQAGRWRE-PSPRAD--PSLLSLEQLLKTENLAEAKASEEDKLKAVMYQSSLCYYSSSEAMRLLG------------------------------IPGHHIRHCPTNVGSRSAPHKRIRKSTGIPRSFLLEVDDPDRKGVMIDGSGRYVIPIIDAEAYAAEKRKRPSFSCQTEPLPS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVRDAGGKRSRSPSSPETRGHQKRPRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GGN2-1", "uniprot_id": "A0AC58GGN2_DANRE", "id": "A0AC58GGN2-1", "name": "", "aln": "-MSCVHYRFQSRLAYDSLRFEGLNITAGELKRQIMRSKRL-KFCQ--LKISNAQTDEEYT-DDALIPKNTSVIIRRIPAAGLKSSNRRFVGHQAGRWGK-PSPRGD--PSLLSLEQLLKTENLAEAKASEEDKLKAVMYQSSLCYYSSSEAMKLLG------------------------------IPGHHIRHCPTNVGSGFAPHKRIRRSTGIPRSFLLEVDDPDRKGVMIDGSGRYVIPIIDAEAYAAEKRKRPSFSCQTEPLPS------------------------------------------------------------------------------------------------------------------------------SSS--------------------------AGAASSVRDAGGKRSRSPSPPETHGDQKRPRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PVA6-1", "uniprot_id": "A0A8M9PVA6_DANRE", "id": "A0A8M9PVA6-1", "name": "", "aln": "-MSCVHYRFQSRLTYDSLQFEGLNITVGELKRQIMRRERL-KFCQ--LKISKAQTDEEYTDDDALIPKNTSVIIRRVPAAGLKSSNRRFVGHQAGPSAK-SSQTGD--SSLLSLEQLLKTENLAEAKASEEDKLKAAMYQSSLCYYSS-----------------------------------------------------------------------------------------------------------------RAAALLH------------------------------------------------------------------------------------------------------------------------------TSA--------------------------SGGAQGFPAASCWRWTTQTERES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ21-1", "uniprot_id": "Q9XZ21_DROME", "id": "Q9XZ21-1", "name": "", "aln": "--MSVHYKFKSTLNFDTITFDGLHISVGDLKREIVQQKRLGKIIDFDLQITNAQSKEEYKDDGFLIPKNTTLIISRIPIAHPTKKGWEPPAAENAFSAA-PAKQDN------------FNMDLSKMQGTEEDKIQAMMMQSTVDYDPKTYHRIKGQSQVGE--------------VPASYRCNKCKKSGHWIKNCPFVGGKD---QQEVKRNTGIPRSFRDKPDAAENESADFVLPAVQNQEIPEDLICGICRDIFVDAVMIPCCGSS--------------------------------------------------------------------------------------------------------------------------------------------------------FCDDCVRTSLLESEDSECPDCKEKNCSPGSLIPNRFLR--------------------------------------------------------------------------------------------NSVNAFKNETGYNKSAAKPAAVKNEEKPPVEKEVEKKPVAEVEPEETEVKPEKQKESETNGSNPPKSESPEPPATTEPSQ---------------------------------------------------------KEKDKYDSDYEDNITIKMPQPAADSTTVPSKRSPSYSHRSESSHRRDRSDYVSDHDHKHQRPSKSESVNKDRSLLPLPIGTLPSYQGHMMAESEEARRSSAYKPPYMQMQRGPPPMHMMSHHMPAYNNGFNNMGQRPPLSYVPYQNQSVHPMRAPYG----------------------SAGGGMNMNMSQPFQSPNLASIYQGVAAKVGSGPIDDPLEAFNRIMKEKERKKVDRFRSSDRHRSRSPDRQRHRFKSPMYEKDNSRDNLKDKRPRSRERKREHSYERHIRHPRSSRQPNDGSKSPGGRIKRSGHRRSASPKPGYKSDYRDKPYNKPSAPKTEAVEPPPPGFEPLQLTDEDGYRNKHPTSSEASQSSKGDSSKKRGENRHEEAPRKRHRSRSISKE-PKPNDSNYRSLTPPAKITTPKMTAAQLRQRESSPKTPEKSHDDYLTAKARIMASQPVINDTEMETNVGKENKAKSPLSK-----------------------------DRKKKKKDKDKAERKKNKKDKRAKKEKGDRQKKSSSVNRSDSDINNSSLMNESNYKVLSPRAQSPSIEIN------------------------AAQLSPTHNATENVNPKSHSILTVGAASDDNLGPRSKLSEANSVNLSKWEIDENILGLEDSSKKAAGAS--DDPSEITSDVLRKAENAIFAKAINAIRPMEFQVIINSKDNSKDRSVVRSDKDRSSSPRRNNSSRS--------------------------VKDRLGTKISNDRSRSRDKSKGRRRAARSSDDDANRGRSDRHGSRKRDNRSRDRAAPSEKRQERSYKRSSPEDDKLRRQNKEQSESKHGKHDQNNSDDSDRRAAKNTKSSDSR--------------------------------------------------------------------------------------------------------------------------------VVSSVTAVVAPPKPCRPDNPFRKFVDTSSSSSLVVKYDNTIQKEGASSDNGMEHRKQRDKKLKKHSKYSSTDSLKSEKRKDPKSKKKSKILKKKKKSKK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35728-1", "uniprot_id": "MPE1_YEAST", "id": "P35728-1", "name": "Protein MPE1", "aln": "MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGTDFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNATRYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFFKSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFE-GKRIRRTTGIPKKFLKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENR---------------------------------------------------------------------------------------------------------------------------------------------------------QIDGDETIWRKGHFKDLPDDLKCPLTGGLLRQP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKTSKCCNIDFSKEALENALVESDFVCPNCETRDILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSLPTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*:*.* . : *:* :: :**::*: ::* . : *:* :.::.*** * :**:.:::*: * * . .: . :**::: : : . : ", "identical_positions": 22, "similar_positions": 42, "identity": "1.21%" }, { "cls_id": "homologset.agr.SGD:S000001548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61334-1", "uniprot_id": "BAP29_MOUSE", "id": "Q61334-1", "name": "B-cell receptor-associated protein 29", "aln": "MTIQWAAVASFLYAEIGLILLFCLPFIPPQRWQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSSTNVVEKNSAIRPSAFEHTQMKLFRS--QRNLYISGFSLFFWLVLRRLVTLITQLAKEIANKGVLKIQAENTNKAAKKFMEENEKLKLGLRN-----DNAEEHLLEAENKKLIESKENLKTELKKASDALLKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKKGL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F288-1", "uniprot_id": "F7F288_RAT", "id": "F7F288-1", "name": "B-cell receptor-associated protein", "aln": "MTIQWAAVASFLYAEIGLILIFCLPFISPQRWHKIFSFSVWTKIASFWNKAFLTIIILLVVLFLDAVREVKKYSSINVVEKNSASRPAAYEQAQMRLFRS--QRNLYISGFSLFFWLVLRRLVTLITQLAKEITNKGVLKIQAENTNKAAKKFMEENERLKLVLKNN----DNTEEHVLETENKKLVEDKERLKTELKKASDALFKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKENKKGL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHQ4-1", "uniprot_id": "BAP29_HUMAN", "id": "Q9UHQ4-1", "name": "B-cell receptor-associated protein 29", "aln": "MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLIVLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRS--QRNLYISGFSLFFWLVLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH----GKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZX74-1", "uniprot_id": "A0A8I5ZX74_RAT", "id": "A0A8I5ZX74-1", "name": "B-cell receptor-associated protein", "aln": "MSLQWTAVATFLYAEVFAVLLLCIPFISPKRWQKIFKSRLVELVVTYGNTFFVVLIVILVLLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRA--QRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGTAEDGGKLDVGSPEMKLEENKILKTDLKKLKDELASTKKKLEKAENEALAMQKQSEGLTKEYDRLLEEHAKLQASVRGPSDKKEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W0M4-1", "uniprot_id": "Q9W0M4_DROME", "id": "Q9W0M4-1", "name": "Endoplasmic reticulum transmembrane protein", "aln": "MSLVWTLIAGFLYAEIALVLLLVLPVLTPYRWNRFFKSKFLSMLGQQAHIYFLLIMGILVIFLLEAIREMRKYSGLQQSNE---VHLNVEMQHSMKLFRA--QRNFYISGFAIFLALVIRRLVNLICTQANLMAQSEASFKQAQSATAAARSLLE----------------NKNTEKAKEAGEDTTLIELNKLRERVQELTSDLNREKKDKEAVKSQAESINREYDRLTEEYSKLQKKITIGGGGNKDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35723-1", "uniprot_id": "YET1_YEAST", "id": "P35723-1", "name": "Endoplasmic reticulum transmembrane protein 1", "aln": "MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRG-IFSTYNQLTAKQQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQRNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSN------------------------------SKKDSNEADSTKLQEELRKKQISLEG-------LQKQVKNLEKYFDEKNQPGNVAAAEASKKGN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :: : :* .*: :::: :*. * :*. : :. :: ::.::: :. : . . . *: ***:**:** : : : : ::.:: .. * . : :. . .*: .: . * :: * : : : :*. : ", "identical_positions": 19, "similar_positions": 65, "identity": "7.63%" }, { "cls_id": "homologset.agr.SGD:S000001550", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V816-1", "uniprot_id": "G3V816_RAT", "id": "G3V816-1", "name": "Nucleoside diphosphate kinase", "aln": "----------------MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQ-----------ASEELLREHYVELRERPFYSRLVKYMGSGPVVAMVWQGLDVVRASRALIGATDPGDAMPGTIRGDFCVEVGKNVIHGSDSVESAQREIALWFREDELLCWEDSAGH-WLYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV85-1", "uniprot_id": "NDKC_MOUSE", "id": "Q9WV85-1", "name": "Nucleoside diphosphate kinase C", "aln": "----------------MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQ-----------ASEELLREHYVELREKPFYSRLVKYMSSGPVVAMVWQGLDVVHASRALIGATDPGDAMPGTIRGDFCMEVGKNVIHGSDSVESAHREIALWFREAELLCWEDSAGH-WLYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13232-1", "uniprot_id": "NDKC_HUMAN", "id": "Q13232-1", "name": "Nucleoside diphosphate kinase C", "aln": "----------------MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQ-----------ASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGH-WLYE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTF3-1", "uniprot_id": "NDKC_DANRE", "id": "Q9PTF3-1", "name": "Nucleoside diphosphate kinase C", "aln": "----------------MIILCLTIFANIFKPGWTGANERTFLAVKPDGVQRRLVGEIIRRFERKGFKLVGMKLLQ-----------ASEAQLRQHYWELREKPFYNGLVKYMSSGPIVAMVWQGLDVVKTARKMLGETNPADSLPGTIRGDYCVEVGRNVIHGSDSVESAAREISLWFEDHELFCYEECGQH-WIYA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01768-1", "uniprot_id": "NDKB_MOUSE", "id": "Q01768-1", "name": "Nucleoside diphosphate kinase B", "aln": "---------------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHD-WVYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19804-1", "uniprot_id": "NDKB_RAT", "id": "P19804-1", "name": "Nucleoside diphosphate kinase B", "aln": "---------------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFKPEELIDYKSCAHD-WVYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22392-1", "uniprot_id": "NDKB_HUMAN", "id": "P22392-1", "name": "Nucleoside diphosphate kinase B", "aln": "---------------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHD-WVYE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B3-1", "uniprot_id": "A0AB13A7B3_DANRE", "id": "A0AB13A7B3-1", "name": "Nucleoside diphosphate kinase", "aln": "--------------------------------MSAKTERTFIAVKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQVCVLMVDQDAVASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQ-WIYE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15532-1", "uniprot_id": "NDKA_MOUSE", "id": "P15532-1", "name": "Nucleoside diphosphate kinase A", "aln": "---------------------------------MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQ-----------ASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQN-WIYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05982-1", "uniprot_id": "NDKA_RAT", "id": "Q05982-1", "name": "Nucleoside diphosphate kinase A", "aln": "---------------------------------MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFIQ-----------ASEDLLKEHYIDLKDRPFFSGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEISLWFQPEELVDYKSCAQN-WIYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15531-1", "uniprot_id": "NDKA_HUMAN", "id": "P15531-1", "name": "Nucleoside diphosphate kinase A", "aln": "---------------------------------MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQ-----------ASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQN-WIYE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QIK4-1", "uniprot_id": "A0A8M9QIK4_DANRE", "id": "A0A8M9QIK4-1", "name": "Nucleoside diphosphate kinase", "aln": "-------MGSGVSSPRPPTTPAAQPDKCTTAPMSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQ-----------ADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQES-WINS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08879-1", "uniprot_id": "NDKA_DROME", "id": "P08879-1", "name": "Nucleoside diphosphate kinase", "aln": "--------------------------------MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTW-----------ASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKD-WIYE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "--------------------------------MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVK-----------ADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAK-WIYE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O00746-1", "uniprot_id": "NDKD_HUMAN", "id": "O00746-1", "name": "Nucleoside diphosphate kinase D, mitochondrial", "aln": "MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQ-----------APESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:: :******* *:..:: ***::*: **.:*: * . * :** : :**: :: :* :**::. **:* :*:: .* ::* *:. : *******: :.:.:*: *.**:*..* ** ***. *: : : ", "identical_positions": 53, "similar_positions": 51, "identity": "26.77%" }, { "cls_id": "homologset.agr.SGD:S000001551", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49793-1", "uniprot_id": "NUP98_RAT", "id": "P49793-1", "name": "Nuclear pore complex protein Nup98-Nup96", "aln": "MFN---KSFG-TPFGGGTGGFG--TTSTFGQNTGFGTTSGGAFG-TSAFGSSNNTGGLFGNSQT---KPGGLFGTSS---FSQPATSTSTGFGFGTSTGTSNSLFG---TANTGTSLFSSQNNAFAQNKP--TGFGNFGTSTSSGGLFG----------------TTNTTSNPFGNTSGSLFGPSSFTAAPTG------TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQN-QVGAGTTTGLFGSSPATSSATGLFSSSTTNSAFSYGQ----NKTAFGTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMG--LFGVTQASQPGGLFGTATN------------------------------TSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLG---------TNTNTSNFG-FGTNNSGSSIFGSKPAAGTLGTGLGTGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTSTAILGFGAPQAP-------VALTDPNASAAQQAVLQQHLNSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTG--TAKSHLFDGLDDDEPSLANGAFMP--KKSIKKLVLKNLNNSNLFS----------------------------------PVNHDSEDLASPSEYPENGERFSFLS----KPVDENHQQDGDDD---------------SLVSRFYTNPIAKPIPQTPESAGNKNNSSSNVEDTFIALNMRAALRNGLEGSSEETSFHDESLQDDRDEIENSAFQIHPAGIVLTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVIVYVDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPPKTTSKKLKTAPLPPAGQATTFQMTLNGKPAPPPQSQSPE------------------VEQLGRVVELDSDMVDITQEPVPDSVLEESVPEDQEPVSASTQIASSLGINPHVLQIMKASLLVDEEDVD-AMEQRFGHFP--SRGDTAQEICSPRLPISASHSSKSRSIVGGLLQSKFASGTFLSPSASVQECRTPRTSSLMNVPSTSPWSVPLPLATVFTVPSPAPEVPLKTVGIRRQPGLVPLEKSITYGK-GKLLMDMALFMGRSFRVGWGPNWTLANSGEQLHGSHELENHQVAESMEYGFLPNPVAVKSLSESPFKVHLEKLGLRQRKLDEDLQLYQTPLELKLKHSTVHVDELCPLIVPNPGVSVIHGYADWVKKSPRDLLELPIVKHWSLTWTLCEALWGHLKELDSQLDEPSEYIQTLERRRAFSRWLSHTAAPQIEEEVSLTRRDSPIEAVFSYLTGSRISEACCLAQQSGDHRLALLLSQLVGSQSVRELLTMQLADWHQLQADSFIHDERLRIFALLAGKPVWQLSEQKQINVCSQLDWKRTLAIHLWYLLPPTASISRALSMYEEAFQNTCEGDKYACPPLPSYLEGSGCVVEEEKDPQRPLQDVCFHLLKLYSDRHYGLNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSEQCEGVLQASYAGQLESEGLWEWAIFVFLHIDNSGMREKAVRELLTRHCQLSETPESWAKETFLTQKLCVPAEWIHEAKAVRAHMESNKHLEALYLFKAGHWNRCHKLVVRHLASDAIINENYDYLKGFLEDLAPPERSSL-IQDWETSGLVYLDYIRVIEMLHRIQQVDCSGYE---LEHLHTKVTSLCNRIEQIPCYNAKDRLAQSDMAKRVANLLRVVLSLQHTPDATSNSTPDPQRVPLRLLAPHIGRLPMPEDYALEELRGLTQSYLRELTVGSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFD9-1", "uniprot_id": "NUP98_MOUSE", "id": "Q6PFD9-1", "name": "Nuclear pore complex protein Nup98-Nup96", "aln": "MFN---KSFG-TPFGGSTGGFG--TTSTFGQNTGFGTTSGGAFG-TSAFGSSNNTGGLFGNSQT---KPGGLFGTSS---FSQPATSTSTGFGFGTSTGTSNSLFG---TASTGTSLFSSQNNAFAQNKP--TGFGNFGTSTSSGGLFG----------------TTNTTSNPFGSTSGSLFGPSSFTAAPTG------TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQN-QVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQ----NKTAFGTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMG--LFGVTQASQPGGLFGTATN------------------------------TSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLG---------TNTNTSNFG-FGTNNSGSSIFGSKPAAGTLGTGLGTGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTSTAILGFGAPQAP-------VALTDPNASAAQQAVLQQHLNSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTG--TAKSHLFDGLDDDEPSLANGAFMP--KKSIKKLVLKNLNNSNLFS----------------------------------PVNHDSEDLASPSEYPENGERFSFLS----KPVDENNQQDGEDD---------------SLVSRFYTNPIAKPIPQTPESVGNKNNSSSNVEDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNAYHIHPAGIVLTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVIVYVDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPPKTTSKKLKTAPLPPAGQATTFQMTLNGKPAPPPQSQSPE------------------VEQLGRVVELDSDMVDITQEPVPDSVLEESVPEDQEPVSASTHIASSLGINPHVLQIMKASLLVDEEDVD-AMDQRFGHIP--SKGETVQEICSPRLPISASHSSKSRSIVGGLLQSKFASGTFLSPSASVQECRTPRTSSRMNIPSTSPWSVPLPLATVFTVPSPAPEVQLKTVGIRRQPGLVPLEKSITYGK-GKLLMDMALFMGRSFRVGWGPNWTLANSGEQLHGSHELENHQVADSMEYGFLPNPVAVKSLSESPFKVHLEKLGLRQRKLDEDLQLYQTPLELKLKHSTVHVDELCPLIVPNPGVSVIHDYADWVKDSPGDFLELPIVKHWSLTWTLCEALWGHLKELDGQLDEPSEYIQTLERRRAFSRWLSHTAAPQIEEEVSLTRRDSPVEAVFSYLTGSRISGACCLAQQSGDHRLALLLSQLVGSQSVRELLTMQLADWHQLQADSFIHDERLRIFALLAGKPVWQLSEQKQINVCSQLDWKRTLAIHLWYLLPPTASISRALSMYEEAFQNTPEGDKYACSPLPSYLEGCGCMVEEEKDSRRPLQDVCFHLLKLYSDRHYELNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSEQCEGVLQASYAGQLESEGLWEWAIFVFLHIDNSGMREKAVRELLTRHCQLSETPESWAKEAFLTQKLCVPAEWIHEAKAVRAHMESNKHLEALYLFKAGHWNRCHKLVIRHLASDAIINENYDYLKGFLEDLAPPERSSL-IQDWETSGLVYLDYIRVIEMLHRIQQVDCSGYE---LEHLHTKVTSLCNRIEQIPCYNAKDRLAQSDMAKRVANLLRVVLSLQHAPDATSNSTPDPQRVPLRLLAPHIGRLPMPEDYALEELRGLTQSYLRELTVGSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52948-1", "uniprot_id": "NUP98_HUMAN", "id": "P52948-1", "name": "Nuclear pore complex protein Nup98-Nup96", "aln": "MFN---KSFG-TPFGGGTGGFG--TTSTFGQNTGFGTTSGGAFG-TSAFGSSNNTGGLFGNSQT---KPGGLFGTSS---FSQPATSTSTGFGFGTSTGTANTLFG---TASTGTSLFSSQNNAFAQNKP--TGFGNFGTSTSSGGLFG----------------TTNTTSNPFGSTSGSLFGPSSFTAAPTG------TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQN-QVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ----NKTAFGTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMG--LFGVTQASQPGGLFGTATN------------------------------TSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLG---------TNTNTSNFG-FGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAP-------VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTG--TAKSHLFDGLDDDEPSLANGAFMP--KKSIKKLVLKNLNNSNLFS----------------------------------PVNRDSENLASPSEYPENGERFSFLS----KPVDENHQQDGDED---------------SLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTPLQMALNGKPAPPPQSQSPE------------------VEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSASTHIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLP--SKADTSQEICSPRLPISASHSSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTMPSPAPEVPLKTVGTRRQLGLVPREKSVTYGK-GKLLMDMALFMGRSFRVGWGPNWTLANSGEQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQTPLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCEALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTSDSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSL-IQDWETSGLVYLDYIRVIEMLRHIQQVDCSGND---LEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCH5-1", "uniprot_id": "NUP98_DROME", "id": "Q9VCH5-1", "name": "Nuclear pore complex protein Nup98-Nup96", "aln": "MFGGAKPSFGATPAATSFGGFSGTTTTTPFGQSAFGKPAAPAFGNTSTFAAQPAQQSLFGAAATPAQPAGGLFGANTSTGFGSTATAQPTAFGAFSQPQQTSNIFGSTQTAASTSLFGQSTLPAFGAAKPTMTAFGQTAAAQPTGSLFGQPAAATSTTGFGGFGTSAPTTTNVFGSGTASAFAQPQATAVGASGVNTGTAVAKYQPTIGTDTLMKSGQANSVNTKQHCITAMKEFEGKSLEELRLEDYMCGRKGPQAGNAPGAFGFGAQVTQPAQPASGGLFGSTAQPSTGLFGQTVTENKSMFGTTAFGQQPA-TNNAFGAATQQNN-FLQKPFGATTTTPFAAPAADASNPFGAKPAFGQGGSLFGQAPATSAAPAFGQTNTGFGGFGTTAGATQQSTLFGATPAADPNKSAFGLGTAASAATTGFGFGAPATSTAGGGLFGNKPATSFAAPTFGATSTASTPFSNFGLNTSTAATGGGLFNSGLNKPATSGFGGFGATSAAPLNFNAGNTGGSLFGNTAKPGGGLFGGGTTTLGGTGAAPTGGLFGGGTTSFGGVGGSLGGGGFGMGTNNSLTGGIMGAQPTLGIMTPSHQPIHQQILARVTSPYGDSPIFKDLKLSS--EADATRATNPAAQQAVLDLTSNQYKISTSNNPAPMKVKALGSTLNRKSLFDGLEEFDASVEGFNLKPSAKRLVIKPKVKSVEGGNPSSSIGSAPNTPQSRPKGATPNKERESFSGAIPSEPLPPAGNSPGATNGRESQDNGRRESWLHPNNLEKVRQHNIQTGMDQGSPHNSTLNELVPRKPLDTYRPSSTVRLSVSTIPENPFEDQSSTIARRETFTSQQANESVLSNRSNEAEDSAANQSRLAIEAAAAEAADDESHPTGIVLRRVGYYTIPSLDDLRSYLAEDGSCVVPNFTVGREGYGNVFFGKEMDVAGLNLDEIVHFRNKEIIIYPDDENKPPIGQGLNRDAQVTLDQVWPLDKTKHEAIKDPQRLLEMDWEGKLRRVCDKNDTRFIEYRPETGSWVFRVKHFSKYGLGDSDEEDE---LPTDPKKAKIATLEAQQRANAEKMTLNSLRQAQKISEDAARNLDPKALVAGVASGFRPMDDTAEFLLMDKTQFFQAGGNSDFSMFDPPRQRPTITSPTAVLAQEMVGNEAHKMQLMKSSFFVEDNAPEDEPMETTGRLLRHRKFFNVEPLVWKDGASESSSQYDFEHPSPALPISSSVSEASLMCDAHYEETSSMATGSIVAAVKETKFEMPVTKAFKFVCKPKVAPIKLRAT-------TVPLPRSIAYEMRDNWIADLGFYKGRSFKLSFGPQNSLVLPSTYNN--MQNLKEFTGPSLPVSMVFAPRSATDLSPSVMQLVEFNMVKGNEGFR-ESIIPHLEVQLNDCLSVNVEGSECPCIHPDSGTKLVS---KHFSESLKQRNAGLKEDYSVSVWSLLFALWGDHDELVDLEKNS--HYMVMCRRNLLSEWLENTLLGKDLLSKKVS-THSYLEHMLDLLSCHRVNEACELAFSYDDANLALVLSQLSSGAVFRLLMEEQLFAWQQSKSDKYIDLERLKMYMLAAGAPMMQSSHG-AINLLENKNWLTALALQLWYFTAPTSSITDALNAYNDAFQ---AEECYAEPPKPSYRDAP-------TDTKKPVYDLRYHLLQLHSKRMHSLEETLNPITHTADAMDFRLSWLLLQTLRALGYRHCSPLTEARLSVDFASQLENEGLWQWGIFVLLHIKQQTQRERAVQQMLQRNVSVSAKVALYAEERFIVEELGIPMSWVDYAKAVKAGASGKHHLQAKYLLKAKHFATAHDVIFQHIAPDAIINGKMKYLHSLLIQFEDTEGSSIRVPNWANQGQIFLDFIDISAKFKQIRSVTNIADINARWENLKPQLSELCSRISLLPCPTSKHRLCQSEISQSLSCLVHGMCIVCPEMESSTVLKVALERLPLPQEFASKELRIWLEELLDKIQNEPPFSERQQPTMMEI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02629-1", "uniprot_id": "NU100_YEAST", "id": "Q02629-1", "name": "Nucleoporin NUP100/NSP100", "aln": "MFGNNRPMFG-----GSNLSFG-SNTSSFGGQQSQQPNSLFGNSNNNNNSTSNNAQSGFGGFTS--------------------AAGSNSNSLFGNNNTQNNGAFG--------QSMGATQNSPFGSLNSSNASNGNTFGGSSSMGSFG------------------GNTNNAFNNNSNSTNSPFGFNKPNTG-------GTLFGSQNNNSAGTSSLFGGQSTSTTGTFGNTGSSFGTGLNGNGSNIFGAGNNSQSN-TTGSLFGNQQSSAFGTNNQQGSLFGQQSQNTNNAFGN-----QNQLGGSSFGSKPVGSGSLFGQSN--------NTLGNTTNNRNGLFGQMNSSNQGSSNSGLFG----QNSMNSSTQGVFGQNNN-------------------------------QMQINGNNNNSLFGKANTFSNSASGGLFGQN-NQQQGSGLFGQNSQTSGSSGLFGQNNQKQPN--------TFTQSNTGIGLFGQNNN-----QQQQSTGLFGAKPAGTTGSLFGG-------NSSTQPNSLFGTTNVPTSNTQSQQGNSLFGATKLT-------------------------------NMPFGG---------------------NPTANQSGSGNSLFGTKPASTTG---------------------------------------------------------------------------------------------------------------------------------------------------------SLFGNNTASTTVPSTNGLFGNNANNSTSTTN--------TGLFGAKPDSQSKPALGGGLFGNSNSNSSTIGQNKPVFGGTTQNTGLFGATGTN------------------SSAVGSTGKLFGQNNNTLNVGTQNVPPVNNTTQNALLGTTAVPSLQQAPVTNEQLFSKISIPNSITNPVKATTSKVNADMKRNSSLTSAYR------LAPKPLFAPSSNGDAKFQKWGK----------------------TLERSDRGSSTSNSITDPESSYLNSN--------------------------------------------DLLFDPDRRYLKHLVIKNNKNLNVINHNDDEASKVKLVTFTTESASK-------------------------------------DDQASSSIAASKLTEKAHSPQTDLKDDHDESTPDPQSKSPNGSTSIPMIENEKISSKVPG-----------------------------LLSNDVTFFKNN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYISPSIETLG---------------------------------------------------------------------------NKSLIELRKINNLVIGHRNYGKVEFLEPVDLLNTPLDT-----LCGDLVTFGPKSCSIYENCSIKPEKGEGINVRCRVTLYSCFPIDKETRKPIKNITHPLLKRSIAKLKENPVYKFESYDPVTGTYSYTIDHPVLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. ** . .*. .*:: : . : . . .. .:. . ** : *:. : .. . ** : : .*. :. :. *: . .: . ** .*.* *.. : * . . :. : . ...: .: . . .:. : . ...*: : : ...:. . . . : : .**.. : : :*: :. :* :: * . ... ** . :.:* :*.. . :. * : * : :.. ** .. . . ** . .:... ***:: .: . * : . . ** : . .:.:* ** .. : * : . * :*. .. . .. :* . . ** *:*. **:*::: : . .:. : ... .:. :. ..: : .: . .. ...: : . . . * ..* : .. : . * . * : : .:. ::: .... . *.: :. . :: . * . *. . .. ::. :. * . :* .. :*.*:* .* : .. . ::.. . *: ::: . :. : . . :* :. :. . . :. : .. :: : . .:* : *: :: .. : : .. . .: :: : ..* : : *:* .:* * * ::. * : :. . . :: . . :. . :. .: :* * : * : . . . : ", "identical_positions": 82, "similar_positions": 318, "identity": "4.11%" }, { "cls_id": "homologset.agr.SGD:S000001554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1N865-1", "uniprot_id": "A0A8M1N865_DANRE", "id": "A0A8M1N865-1", "name": "", "aln": "MAALEACTALVTGANRGLGLEMVKQLLEADCS--KIFAACRDTDGPNSEVLRELAKKNPDVVTLVKLDVADPASIKESAKKVGSLLGEKGLNLLVNNAAILPQKTMLTCSV-EDMHNTFNTNVIGPLFVIREYLPYLRAAVKASGKPGMSPGKAAVINISTDAASLNMIPSMKEPFPLFPYSISKVALNMLTVYTARDLKADEILCISIHPGWVRTDMGSY--------------EATLDTRESVEGMLRVIGSLTEKDQGGYMDYTGKTMPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NBQ4-1", "uniprot_id": "A0A8M1NBQ4_DANRE", "id": "A0A8M1NBQ4-1", "name": "", "aln": "MASVICDSVLVTGSNRGIGLELVHQLVDLPKSPGHIFAGCRDPGGPKAQELRDLAQKHQGVITVVQLDTDSPDSIKEASNLVESKLNGKGLNLIINNAGVNIPGSLVETGK-KEMVDSYTTNVVGPMLIAKNFHPLLCKAAAQFPQSSMSCSRSAIVNVSTLLSSITRCPENFYRSPMYPYRICKAALNMLTRCLAEDFRKDGILVASLHPGWVQTEMGGP--------------QAPLTTAESVSGMIKVITSLTEKDSGTLLDWEGNNIPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3H4-1", "uniprot_id": "Q9W3H4_DROME", "id": "Q9W3H4-1", "name": "", "aln": "-----MNSILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNRE--QAKELEDLAKNHSN-IHILEIDLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDG----GMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWVKTDMGGS--------------SAPLDVPTSTGQIVQTISKLGEKQNGGFVNYDGTPLAW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36086-1", "uniprot_id": "YKH1_YEAST", "id": "P36086-1", "name": "Uncharacterized oxidoreductase YKL071W", "aln": "MNTSSRITYFIIGGSRGIGFNLVKILSASTGN-TVITSIRGSPSLPKNKQVEDLAKIRKN-IHIVQLDLTKDESIGNIADEIKKTPFFLGIDIFIACSAVSDSYYKVLETPKSVWLNHYSTNALGPILALQKVYPLLLLKKTR-----------KIFFISSVAGSINAFVPLS----VSAYGQSKAALNYAVKTLSFELKPEGFTVVAFHPGMVSTDMGQYGLDHFKEKNIDISGVNIITPEESASALIDVFRKILPEDNGKFFNYDGSEGVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * .**:*: :*: * : : . : : :.:**: . . : ::::* . : : : *::::. :.: : . : **.: *:: : * * :. :*: .*: : .* .* *** . : :: : : ::*** * *:** : *. :: .: .: ::.* .:: *. :", "identical_positions": 32, "similar_positions": 78, "identity": "11.72%" }, { "cls_id": "homologset.agr.SGD:S000001556", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKR6-1", "uniprot_id": "HYOU1_MOUSE", "id": "Q9JKR6-1", "name": "Hypoxia up-regulated protein 1", "aln": "MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKEN-----------ERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPH-VALYRSRFPEHELIVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPAFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINSTAQNVMFYDMGSGSTVCTIVTYQTVKTKEA-GMQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAE----MSLDQIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEPPAEETSQPPPSEPKGDAAREGEKPDEKESGDKPEAQKPNEKGQAGPEGAAPAPEEDKKPKPARKQKMVEEIGVELAVLDLPDLPEDELARSVQKLEELTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGAR-LIPEMD---QVFTEVEMTTLEKVINDTWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASAGDQEEKVIPPAG--QTEEAKPILEPDKEETGTEPADSEPLELGGPGAGPEQEEQSAGQKRP-SKNDEL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63617-1", "uniprot_id": "HYOU1_RAT", "id": "Q63617-1", "name": "Hypoxia up-regulated protein 1", "aln": "MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKEN-----------ERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPH-VALYRSRFPEHELNVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPAFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINSTAQNIMFYDMGSGSTVCTIVTYQTVKTKEA-GTQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAE----MSLDQIEQVILVGGPTRVPKVQEVLLKPVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEAPMEDTSQPPPSEPKGDAAREGETPDEKESGDKSEAQKPNEKGQAGPEGVPPAPEEEKKQKPARKQKMVEEIGVELAVLDLPDLPEDELAHSVQKLEDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGAR-LIPEMD---QIFTDVEMTTLEKVINDTWTWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRTEPPLNASAGDQEEKVIPPTG--QTEEAKAILEPDKEGLGTEAADSEPLELGGPGAESEQAEQTAGQKRP-LKNDEL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4L1-1", "uniprot_id": "HYOU1_HUMAN", "id": "Q9Y4L1-1", "name": "Hypoxia up-regulated protein 1", "aln": "MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKEN-----------ERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPH-VALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPVFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEA-GMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAE----MSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR-LIPEMD---QIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAG--QTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRP-LKNDEL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW2-1", "uniprot_id": "HYOU1_DANRE", "id": "Q7ZUW2-1", "name": "Hypoxia up-regulated protein 1", "aln": "--------MREKLSLWAIFCLVVAFLPSQTESVAVMSVDLGSEWMKVAIVKPGVPMEIVLNKESRRKTPVAVCLKEN-----------ERLFGDGALGVAVKNPKVVYRFLQSILGKTADNPQ-VAEYQKHFPEHQLQKDEKRGTVYFKFSEEMQYTPEELLGMILNYSRTLAQDFAEQP-------IKDAVITVPAYFNQAERRAVLQAAHIAG-LKVLQLINDNTAVALNYGVFRRKDINSTAQNIMFYDMGSGSTTATIVTYQTVKTKES-GTQPQLQIRGVGFDRTLGGFEMELRLRDHLAKLFNEQKKSK--KDVRDNLRAMAKLLKEAQRLKTVLSANAEHTAQIEGLMDDIDFKAKVTRSEFEALCEDLFDRVPGPVKQALAAAE----MSMDEIEQVILVGGATRVPKVQDVLLKSVGKEELSKNINADEAAAMGAVYQAAALSKAFKVKPFLVRDAAVFPIQVEFSRETEEEDGVKSLKHNKRILFQRMAPYPQRKVITFNRYIDDFVFYINYGDLSFLSEQDMKVFGSQNLTTVKLSGVGSSFKKHSD--AESKGIKAHFNMDESGVLILDRVESVFET-IVEEK-EEESTLTKLGNTISSLFGGGSS-EPSANVTEPVTDEEEVTPEAGKEQ--DQPEKQEETVQEKPETEEGKEAEPQAEEQKEDKEKAENQGETESEKTEKPEEKTTDEE-----KEADMKPKLQKKSKISADIAVELEVNDVLDPSAEDMEGSKKKLQDLTDRDLEKQEREKTLNSLEAFIFETQDKLYQDEYQAVVTEEEKEQISGRLSVASSWMDEEGYRAGTKLLKEKLSELKKLCKGMFFRVEERKKWPDRLAALDSMLNHSNIFLKSAR-LIPESD---QIFTDVELKTLEKVINETITWKNETVAEQEKLSPTVKPVLLSKDIEAKLSLLDR-----EVNYLLNKAKFAKPKPKDKAKDKNSTSESSKANSTDDAEKVIPPK---TEDGAEKVKPAEEPPVVEEKAEETILELNPAENTDDKTESTESSKSENHIEDEL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46067-1", "uniprot_id": "O46067_DROME", "id": "O46067-1", "name": "Hypoxia up-regulated protein 1", "aln": "------------MKLVLLLSALLAG-IALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDG-----------TRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPI-VDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESVQQP-------ITECVLTVPGYFGQAEREALLSAAQLAN-LKVLQLINDYAAVALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTK--TDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSH----LSLDVINQVILFGGGTRVPRVQET-IKAVIKQELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDG---AAVKQVKRALFALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFT-------KEG------EEKKDNSE------------QEEAANAGEEPSKS-----------EDNEKAKEEDASKEQKSEESTK-----------QDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKDVFTQVEIDTLDKVITETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDR-----EVKYLVNKIKIWKPKVKPAAEKEKKKEEEVVASGSGDDTK---------SEDAE---QQQEQATKEEQQEQEPVDEITPTPAEEETKTPHSEL-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36016-1", "uniprot_id": "LHS1_YEAST", "id": "P36016-1", "name": "Heat shock protein 70 homolog LHS1", "aln": "-------------MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTN-RSTIAFLVD-NVEYPLEELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQ---PVTIEFEGYGYNPHLGGAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIESLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGGSSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVNTYSFKLSNE-----------SELYDVFTRGSAYPNKTSILTN----TTDSIPNNFTIDLFENG--KLFETITVNSGAIKNSYSSDKCSSG-----VAYNITFDLSSDRLFSIQEVNCICQS---ENDIGNSKQIKNKG----------------------------------------------------------------------------------------------------------------------SRLAFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDDEVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDS-AKEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQPAYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEKLRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADDKTTIVNDKTTESNPSSEEDILHDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: : . **:.** *.: :*. :*.* .*:*:.*. *::** : :: * *. . :. : *: . .: :*** :: * * :.* :: * *: * . ::. **::. : *:. :: :.. :*:* :*.* :*.*:*.*: :: :: *:.: :.*:.: : :* * :.****: . .::.: : . ::. * *:: *** :: : : . : * : :: . :*:**: : * : * :****:: :**.*::*:**: :** ::* : * *:::*: .: *: *** ** :*:* **: :* * :::: :*:****:*. *.* :. ** .**.* : * * : . ..: .: :* .**::. * * * :. : : .:.. :. . : . : * :... :: *: : :. *:. :.. :.: * : : . :: : : :: . :. * **: : :.:: * : . . .: *:: .. *: : . . .:: :: * : : . : * :..::: . :* . : . * *:::* : : . : . :.* * : ::. : : *: : :. . .: * : : : : . : . ", "identical_positions": 125, "similar_positions": 273, "identity": "11.98%" }, { "cls_id": "homologset.agr.SGD:S000001557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F2Z3T9-1", "uniprot_id": "F2Z3T9_RAT", "id": "F2Z3T9-1", "name": "Splicing factor U2AF subunit", "aln": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAP-----GNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQP--LPGMSEN------------------PSVYVPG------VVSTVVPDSAHKLFIG--GLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKG--------------------YAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK-NATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26369-1", "uniprot_id": "U2AF2_MOUSE", "id": "P26369-1", "name": "Splicing factor U2AF 65 kDa subunit", "aln": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAP-----GNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQP--LPGMSEN------------------PSVYVPG------VVSTVVPDSAHKLFIG--GLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKG--------------------YAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK-NATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26368-1", "uniprot_id": "U2AF2_HUMAN", "id": "P26368-1", "name": "Splicing factor U2AF 65 kDa subunit", "aln": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAP-----GNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQP--LPGMSEN------------------PSVYVPG------VVSTVVPDSAHKLFIG--GLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKG--------------------YAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK-NATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24562-1", "uniprot_id": "U2AF2_DROME", "id": "Q24562-1", "name": "Splicing factor U2AF 50 kDa subunit", "aln": "----------MGYDDRERDRERRR-----HRSRSRDR-HRERSRDRRHH------RNSRR--------------------------KPSLYWDVPPPGFEHITPMQYKAMQASGQIPAS-----VVPD---TPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAA-----GSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQP--MPGITDTPAI--------------KPAVVSSG------VISTVVPDSPHKIFIG--GLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKG--------------------YAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAK-NAQNAAN----TTQSVMLQVPGLSN--VVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIEG---VEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKYHRREF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1T4-1", "uniprot_id": "Q9W1T4_DROME", "id": "Q9W1T4-1", "name": "Splicing factor U2AF subunit", "aln": "MRRFRPMNRSWN-ALRSRSR-SRSRSRSPFRSQSITRSRPTRSDTIYTER----TRLQRRFS------------------------RPPSSWDIPPEGYNHLTPQQYKAMLASGQIASR-----ILSDG---VHGGESAAISMITRQARRLYVGNIPFGVTDEEMMQFFNHQIMALGFEAKSSHYMDGNAVLTCQTNLEKNFAFLEFRSIDEASQALNFDGMVFRGQTLKIRRPHDYQP--VPSISVSAMESYRSFR--------VPAINVAQQPAVTLPVTTIVPDSPNKIYVG--GLPTCLNQDQVKELLQSFGELKGLNLVMDTNTNLNKG--------------------FAFFEYCDPSVTDHAIAGLHGMLLGDRRLVVQRSIPGGK-NAFPGHLP-------TVLQVPGIST--LQDPGSPTETLCLLNMVRPEELLDDEEFEDIRTDIKQECAKFGEVRSIKIPRPIGQ---FPKRGCGKVFVQFESVEDSQKALKALSGRKFSGRIVMTSYYDPEKYLADDLQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36084-1", "uniprot_id": "MUD2_YEAST", "id": "P36084-1", "name": "Splicing factor MUD2", "aln": "MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPS-------SIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASS-KANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKYSIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTVLCTYIDEDDFDMMEATQLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .: : : . . * : . : . :: .: .: : . : *:.*. . *. : . ** : : .. : . .. *: :: * ::.. : :.*: .:. : * :* :..: . * .:. * : :* .* :* *::* .. :. :. : .:.:* * : . . . : : * . .::.* * : . .: . :..* *:* : * :* *: :* :: . : . :: : *.*:::::* :: .::* : *.* :* .* *: .* * :.: : ", "identical_positions": 41, "similar_positions": 131, "identity": "7.66%" }, { "cls_id": "homologset.agr.SGD:S000001561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VY9-1", "uniprot_id": "DHX33_MOUSE", "id": "Q80VY9-1", "name": "ATP-dependent RNA helicase DHX33", "aln": "-------MPEEASLPPAKRFRPGS--------CPPGRRVVMLLTAGGGG-GAGGGRRQTPPLAQPSASPYREALELQRRSLPIFRARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGIS--RQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFEDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKTAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNRAPVLYLEGRQHPIQIFYTKQPQQDYLHAALVSVFQIHQEAPASQDILVFLTGQEEIEAMSKTCRDIARHLPDGCPS--MLVLPLYASLPYSQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFEKMTVPEIQRCNLASVILQLLAMKVPNVLTFDFMSKPSPDHIEAAIAQLDLLGALEHKDDQLTLTPIGRKMAAFPLEPRFAKTILLSSKFHCTEEILTIVSLLSVDSVLYNP-PARRDEVQSVRKKFISS---EGDHITLLNIYRTFKNIGGN--------KDWCKENFVNSKNMLLVAEVRAQLREICLKMSMPIMSSRGDMESVR----------RCMAHSLFMNTAELQTDGTYATTDTHQPVAIHPSSVLF-HCKPACVVYTSLLYTNKCYMRDLCVVDAEWLYEAAPDYFRRKLRTARN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSV6-1", "uniprot_id": "D3ZSV6_RAT", "id": "D3ZSV6-1", "name": "ATP-dependent RNA helicase DHX33", "aln": "-------MPEEAGLPPAKRFRPGS--------CPPGRRVVMLLTAGSGG-GAGGGRRQTPPLAQPSASPYREALELQRRSLPIFRARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGIS--RQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFEDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKTAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVLYLEGRQHPIQIFYTKQPQQDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLPDGCPS--MLVLPLYASLPYSQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFDKFEKMAAPEIQRCNLASVMLQLLAMKVPNVLTFDFMSRPSPDHIEAAIAQLDLLGALEHKDDQLALTPIGRKMAAFPLEPKFAKTILLSSKFHCTEEILTIVSLLSVDSVLYNP-PARRDEVQSVRKKFISS---EGDHITLLNIYRTFKNIGGN--------KDWCKENFVNSKNMLLVAEVRAQLRDICLKMSMPIMSSRGDMESVR----------RCLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLF-HCKPACVVYTSLLYTNKCYMRDLCVVDAEWLYEAAPDYFRRKLRTARN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6R0-1", "uniprot_id": "DHX33_HUMAN", "id": "Q9H6R0-1", "name": "ATP-dependent RNA helicase DHX33", "aln": "-------MPEEAGFPPAKRFRPGSGPPSRAGSFPPGRQVVMLLTAGSGGRGGGGGRRQQPPLAQPSASPYPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGIS--RQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVLYLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLPDGCPA--MLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLHNP-PSRREEVQGVRKKFISS---EGDHMTLLNIYRTFKNLGGN--------KDWCKENFVNSKNMTLVAEVRAQLRDICLKMSMPIASSRGDVESVR----------RCLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLF-HCKPACVVYTELLYTNKCYMRDLCVIDAQWLYEAAPEYFRRKLRTARN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL25-1", "uniprot_id": "DHX33_DROME", "id": "Q9VL25-1", "name": "ATP-dependent RNA helicase DHX33", "aln": "--------MDSKYFATSRNDAVGPSP----VKFSFKRKYDAMANSPILE-KKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYA--KNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFN-CKGMYLEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTD--LRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDID-CNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDD-SYITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSN-SEKNEMAALAHAKFQSK---HGDHLTLLNVFNGFLKSEKP--------KMWCHDNYLNLRSLTYARNVRRQLREISEHLHLALNSS-DDIEMLK----------KCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVP--FVKNIPTR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36009-1", "uniprot_id": "DHR2_YEAST", "id": "P36009-1", "name": "Probable ATP-dependent RNA helicase DHR2", "aln": "MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFNDSGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRP----DLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIVDAVIRCCIQINQGEELG-DILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLYAALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVLMLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGK---ITKRGQQMALLPLQPHLSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDLIMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSSISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSMLFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEVVTNAAAVAKQKVSDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . : : : . :: .. : :.:**::. : .:: :. .:::.******:*****:: ::* *.:*********.:* **::* :*. ***:***::.*: *::::****:**** : : * :** :::*******: :*:::*.:* : : *:::* ***:: : *.::** . :::*** . :: : * :* :.:.: ::*:: . *:* **.*****: ..:*: . . : .*** *. :* * ***:::*******:**.*:: *:* *: * * :. ** .* :*::.* **:*****: .* .:* * : : .: . : *** * : :* :* * : .: ::. * : : . .* ***:. .. :* *::*. **:*: :. :: :... * .::: :** ** : :: . . ..: . : .: . ** : * ::: : : **: :. :.: . .** *** . :: .: .. : : : :*: .:: . * * * *.. *****:*. : . . :::*. : * : : *:: :. .*: *... . ", "identical_positions": 170, "similar_positions": 240, "identity": "22.88%" }, { "cls_id": "homologset.agr.SGD:S000001562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97329-1", "uniprot_id": "KI20A_MOUSE", "id": "P97329-1", "name": "Kinesin-like protein KIF20A", "aln": "MSHRILSPPAGLLSDEDVVDSPILESTAADLRSVVRKD----LLSDCSVISASLE--------------DKQ-ALLEDTSEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFA----LKSNERGVGQATHKFTFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQG-------TSKDAGILPQSLALIFNSLQGQLHPTPDLKP----------------------LLSNEVIWLDSKQIRQEEMKKLSLLIGGLQEEELSTSVKKRVHTESRIGASNSFDSGVAGLSSTSQFTSSSQLDETSQLWAQPDTVPVS----VPADIRFSVWISFFEIYNELLYDLLEPPS--HQHKRQTLRLCEDQNGNPYVKDLNWIHVRDVEEAWKLLKVGRKNQSFASTHMNQQSSRS-----HSIFSIRILHLQGEGDIVPKISELSLCDLAGSE----RCKHQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQ-NLIPFRDSK--------------LTRVFQGFFTGRGRSCMIVNVNPCASTYDETLH-------------------AAKFSALASQLVHAPPVHLGIPSLHSFIKKHSPQVGPGLEKEDKADSDLEDSPEDEADVSVYGKEELLQVVEAMKALLLKERQEKL------QLEIQLREEICNEMVEQMQQREQWCSERLDNQKELMEELYEEKLKILKESLTTFYQEQIQERDEKIEELETLLQEAKQQ-PAAQQS-----GGLSLLRRSQRLAASAS------TQQFQEVKAELEQCKTELSS-------TTAELHKYQQVLKPPPPAKPFTIDVDKKLE-----EGQKNIRLLRTELQKLGQSLQSAERACCHSTGAGK----------------------------LRQALTNCDDILIKQNQTLAELQNNMVLVKLDLQKKAAC----------IAEQYHTVLKLQGQASAK----KRLGANQENQQPNHQPPGKKPFLRNLLP-RTP-------TCQSSTDSSPYARILRSRH-SPLLKS-PFGKKY------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95235-1", "uniprot_id": "KI20A_HUMAN", "id": "O95235-1", "name": "Kinesin-like protein KIF20A", "aln": "MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKN----LLSDCSVVSTSLE--------------DKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFA----LKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQG-------TIKDGGILPRSLALIFNSLQGQLHPTPDLKP----------------------LLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLP----VPANIRFSIWISFFEIYNELLYDLLEPPS--QQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRS-----HSIFSIRILHLQGEGDIVPKISELSLCDLAGSE----RCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQ-NLVPFRDSK--------------LTRVFQGFFTGRGRSCMIVNVNPCASTYDETLH-------------------VAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKL------QLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQS-----GSELALRRSQRLAASAS------TQQLQEVKAKLQQCKAELNS-------TTEELHKYQKMLEPPPSAKPFTIDVDKKLE-----EGQKNIRLLRTELQKLGESLQSAERACCHSTGAGK----------------------------LRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAAC----------IAEQYHTVLKLQGQVSAK----KRLGTNQENQQPNQQPPGKKPFLRNLLP-RTP-------TCQSSTDCSPYARILRSRR-SPLLKSGPFGKKY------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDF0-1", "uniprot_id": "F1QDF0_DANRE", "id": "F1QDF0-1", "name": "Kinesin-like protein", "aln": "---MALASPCGILSDEEECG-AVFESTAADVVGLMRSQRFVSPLPEISVITPAADSLTPTKELVQIKSDISRRGSTDDGSDKLKVFLRIRPLTEAEKDRGEEQGCVNVQSEDNLLLKAPKDSRN----MKSAERGVAQSVHKFTFTKIFGPQTSQQEVYDHTIREMVRDVLRGENRLLYTYGVTNSGKTYTIQG-------AGAEAGLLPRALVSVFLKLSGRLYTAMDLKP----------------------VLSQEVRKLDVGEVRAEEMRRDALLK----EDESN---------QSRLRAGLSWDSGISGLSATSHIAT--QLEDSDGVCLEANGLCLSGGEDLEEGVQFSVWVSFYEIYNEFLYDLLDAPPSLQSRKRVTLRLSDDKHGNPYVKDLTWIQVHSAEEAWKVLKVGQRNQSFASTHLNHNSSRS-----HSIFTIRVLHVKPQLGQVTRISELSVCDLAGSE----RCKAQQNGERMKEANNINTSLLTLGRCITALRHNQTNKSRPPVVVPFRDSK--------------LTRVLQSFFCGHGRSCMVVNINPCASTYDETLQ-------------------ALKFSAIATQLVHGPCSKTRVAYILSLLREQ-----PTHPNDTTLLEEDEEESDEEGDITMFDPEALLKAIDVLKREVLRQRQEKE------ELEAKVREEVCTEMMEVISRMQDDFSETLESERDLMEKRCENKINNLKSSLKKYYSQELEERDDEIRELTAALKEKEAGNTAPAAIFP-PLNDDGGLRRSQRLASTHKRDADHESIELFRCKAELENCRAELDLKQTELRLKTLELKRFQDNLPSMGVTGTLTTTAERKLE-----EGQRNLKQLRMELQLLGIKLQSGERACCRNTDGEK----------------------------LRHALSSADSKLAKQDQMLVELHTSLQLVKAELRKKDEL----------LTRFQNTQQAQSHQPPTASGSCKKRGCGVAVALAENQPPEKRPFFRSLFPSRTPSKTPSRPTRQQNEVTTPYSRVLRSRQPSPPTTPVMLRVKY------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32364-1", "uniprot_id": "SMY1_YEAST", "id": "P32364-1", "name": "Kinesin-related protein SMY1", "aln": "----------------------------MHWNIISKEQ------SSSSVSLPTLD-----------------------SSEPCHIEVILRAIPEKGLQNNE--STFKIDPYENTVLFRTNNPLH----ETTKET-----HSTFQFDKVFDANATQEDVQKFLVHPIINDVLNGYNGTVITYGPSFSGKSYSLIG-------SKESEGILPNICKTLFDTLE-----------------------------------------------KNEETK----------------------------------------------------------------------------GDSFSVSVLAFEIYMEKTYDLLVPLP---ERKPLKLHRSSSK-MDLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMACGDKTERSRS-----HLVFQLHVEQRNRK-DDILKNSSLYLVDLHGAEKFDKRTESTLSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQ--------------LTEVLKDSLGGNRKTKVILTC--FLSNVPTTLS-------------------TLEFGDSIRQINNKVTDNTTG---------------LNLKKKMDLFIQDMKIKDDNYVAQINILKAEIDSLKSLHNKSLPEDDEK-------------------KMLENTKKENIKLKLQLDSITQLLSSSTNEDP---NNRIDEEVSEILTKRCEQIAQLELSFDR--------------------------QMNSNSK------------LQQELEYKKSKEEA------------------------LESMNVRLLEQIQ-----LQEREIQELLTTNAILKGELET--HTKLTETRSER----------------------------IKSLESSVKELSLNKSAIPSPRRGSMSSSSGNTMLHIEE----------GSEISNSPWSANTSSKPLVWGARKVSSSSIATTGSQESFVARPFKKGLNLHSIK--------VTSSTPKSPSSGS-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O16844-1", "uniprot_id": "COS_DROME", "id": "O16844-1", "name": "Kinesin-like protein costa", "aln": "MEIPIQVAVRIFPHRELKDLLRSFGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPS-------ISETDPNGNAEQDSAADSKTIPDANGNDSGQKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLCVRDIFSHISLHPERTYAINVGFVEICGGDVCDLLGMGNIHCTNVDAVFHWLQVGLSARQSLPAHTLFTLTLEQQWVSKEGLLQHRLSTASFSDLCGTERCGDQPPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAEPVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLKQECEECLSSTEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDTDNESHRPDLDDKIESLMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDRKVSIGSRRRSVQPGASLSTAELAMLNRVASQQPPPPIDPESVVDPLESSSGEGIRQAALAAAAATAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKKQLGKALVQGRDQSEIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQQSVGESRKQADDLQKKLRKECKLRCQMEAELAKLRESRETGKELVKAQGSPEQQGRQLKAVQARITHLNHILREKSDNLEEQPGPEQQETLRHEIRNLRGTRDLLLEERCHLDRKLKRDKVLTQKEERKLLECDEAIEAIDAAIEFKNEMITGHRSIDTSDRIQREKGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVRQARLEGERNAVLLQRQHEMKLTLMLRHMAEETSASSASYGERALAPACVAPPVQASSDFDYDHFYKGGGNPSKALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFHVLTRYASAAAAGSSGSTAEESTALIESTTTATATTTSTTTTGAVGKVKDKALVSFRPEQLKRLMPAPTATKVTRQKNKIIIQDASRRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .. .* . : : . : : . . * .. . . . : : .. * . . : :: .*.* : : *** .**:::: * : *:: :* :. :. . : .: . :: . .: .* . :::: :. . :: . . : : . . : . . : . : * . : . : : . :. . :.: . : : .. : :: . *. :: .:. .: . : :. :. : : : * :::: . . . .. .* . : . : : .. : . * .* :. : . : :* : . . :. .: : .: . * * : . : :: . . ... .: : .: . . . . . : :. : ", "identical_positions": 23, "similar_positions": 177, "identity": "1.9%" }, { "cls_id": "homologset.agr.SGD:S000001563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVI6-1", "uniprot_id": "VATC1_RAT", "id": "Q5FVI6-1", "name": "V-type proton ATPase subunit C 1", "aln": "-------MTEFWLISAPGEKTCQQTWEKLHA---ATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLASG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFKKAVDDFRHKARENKFIVRDFQYNEEEMRADKEEMNRLSTDKKKQF----------------------------------------------GPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNKKS-VKKLREVLHELYKHLD------SSAAAIID-APMDIPGLNLSQQEYYPYVYYKIDCNLLEFK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1G3-1", "uniprot_id": "VATC1_MOUSE", "id": "Q9Z1G3-1", "name": "V-type proton ATPase subunit C 1", "aln": "-------MTEFWLISAPGEKTCQQTWEKLHA---ATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLASG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMTRLSTDKKKQF----------------------------------------------GPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNKKS-VKKLREVLHELYKHLD------SSAAAIID-APMDIPGLNLSQQEYYPYVYYKIDCNLLEFK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21283-1", "uniprot_id": "VATC1_HUMAN", "id": "P21283-1", "name": "V-type proton ATPase subunit C 1", "aln": "-------MTEFWLISAPGEKTCQQTWEKLHA---ATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQF----------------------------------------------GPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKT-LKKLREVLHELYKHLD------SSAAAIID-APMDIPGLNLSQQEYYPYVYYKIDCNLLEFK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T385-1", "uniprot_id": "VTC1A_DANRE", "id": "Q7T385-1", "name": "V-type proton ATPase subunit C 1-A", "aln": "-------MTEFWLISAPGEKTCQQTWDKLMT---ATTRTNNLSTNNKFNIPDLKVGTLDVLVGLSDELAKLDAFVESVVKKVAQYMADVLEDSRDKVQENLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLVTYVTRFQWDMAKYPIKQSLKNISEIISKQVSQIDNDLKARASAYNNLKGNLQNLERKNAGSLLTRSLADIVKKDDFVLDSEYLITLLVVVPKTNYTDWQRTYETLAEMVVPRSTNLLFEDHDSGLFTVTLFRKAIDDFRHKARENKFTVRDFQYNEEEMKADKEEMTRLSTDKKKQF----------------------------------------------GPLVRWLKVNFSEAFIAWVHIKALRVFVESVLRYGLPVNFQAMLLQPNKKN-MKKLREVLYDLYKHLD------SSAAAIIDQSAMDIPGLNLSQQEYYPYVYYKIDCNLLDFK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5XIY6-1", "uniprot_id": "VTC1B_DANRE", "id": "Q5XIY6-1", "name": "V-type proton ATPase subunit C 1-B", "aln": "-------MTEFWLISAPGDKTCQQTWDKMNM---ATAESNNLSTNNKFNIPELKVGTLDVLVGLSDELAKLDTFVESVVKKIAQYMTDVLEDSRDKVQENLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLVTYITRFQWDMAKYPIKQSLKSISEIMSKQVTQIDNDLKARASAYNSLKGSLQSLERKNVGSLLTRSLADIVKKEDFVLDSEYLTTLLVIVSKTNYPEWQKTYETLSEMVVPRSTKLLFEDQESGLFSVTLFTKAIDDFKQQARENKFMVRDFLYNEEEMKADKEEMTRLSTDKKKQF----------------------------------------------GPLVRWLKVNFSETFIAWIHIKALRVFTESVLRYGLPVNFQAMLLQPNKKN-VKKLREVLKDLYKHLD------SSAAVIDG--SVDIPGLNLSQQEYYPYVYYKIDVNLLELK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V7N5-1", "uniprot_id": "VATC_DROME", "id": "Q9V7N5-1", "name": "V-type proton ATPase subunit C", "aln": "------MMSEYWIISAPGDKTCQQTYDTMNN---LTSKQHNLCNNYKFHIPDLKVGTLDQLVGLSDDLGKLDTYVEQITRKVANYLGEVLEDQRDKLHENLMANNSPGPPDDSMPCRHHQRIKHLSLRHQRKHQHTHHQNKPQHYHHHHHHHQLPQDLKGKSAATCSPATPPAPASAPPHLPPACACDVLAPGSLTGGSLTNLSTSHEPEPEFDVCPCDECFACAPPSTSATASTLLADECYSQTASSMLSATRCALSTVAAIATGSGLGNGPSTSAAAAAAASNSSGGGGGGGPASCSTLCSSAYFSTSAPTTSSSVHSSMSRSNSKRLNNNTCSINNNKLSFRSGSHVSQLHLATQQPQHHHSHPHQQPHTNPLQSPVQKSMSEDEGDASNAHEDGETDEDPKSPHSVQSDLSDAFDWWFNKPKRNSKKSSAQQQHETAQLQHQQTTQQHATPLTPQNHNQYQNQHLSKAMTFWHQASTTPRSSYRSFFNSLADQIYSKRSTPSQLNINNGFNLTPTHRSSPVSSCCGSSSQGRSSPDTDPAEPPEFPLSPAELPQYLTRFQWDMAKYPIKQSLRNIADIISKQIGQIDGDLKTKSQAYNNLKGNLQNLEKKKTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKVMANDWLTNYEKITDMIVPRSSQLIQEDADYCLFNVTLFKKVAEEFKLHARERKFIVRDFVYNEEELAAGKNEMTKLMTDKKKQF----------------------------------------------GPLVRWLKVNFSEAFCALIHVKALRVFVESVLRYGLPVNFQAILIEPNKKS-VKRLRDVLNQLYGHLDG----ASAGGAVSSADNVDIPGLGFGQSEYFPYVFYKVNIDMVEQAKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99L60-1", "uniprot_id": "VATC2_MOUSE", "id": "Q99L60-1", "name": "V-type proton ATPase subunit C 2", "aln": "-------MSEFWLISAPGDKENLQALERMNN---VTSKS-NLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKAHETLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKRSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSFAQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYPTSCVALKKGSATYRDHKVKVAPLGNPARPAAGQTDRDRESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLD-----EVAAASILD-ASVEIPGLQLSNQDYFPYVYFHIDLSLLD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYE4-1", "uniprot_id": "VATC2_RAT", "id": "Q6AYE4-1", "name": "V-type proton ATPase subunit C 2", "aln": "-------MSEFWLISAPGDKENLQALERMNS---VTSKS-NLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKVHENLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKKSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSYVQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYQTSCVALKKGSATYRDHKVKVTPLGNPTRPTAGQND--RESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLD-----EVAAASILD-ASVEIPGLQLSNQDYFPYVYFHIDLSLLD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NEY4-1", "uniprot_id": "VATC2_HUMAN", "id": "Q8NEY4-1", "name": "V-type proton ATPase subunit C 2", "aln": "-------MSEFWLISAPGDKENLQALERMNT---VTSKS-NLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLTSFVTHFEWDMAKYPVKQPLVSVVDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLGNPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLD-----EVAATSILD-ASVEIPGLQLNNQDYFPYVYFHIDLSLLD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PF27-1", "uniprot_id": "A0A8M9PF27_DANRE", "id": "A0A8M9PF27-1", "name": "V-type proton ATPase subunit C", "aln": "--------MEFWLISVPLDKISCQSVEKLKR---VAAKN-GQSASSRMHIPELKVGTLDVLLGLSDDLSRLDSFTEGVMRQTSQCLAEVMDEFSGKLLESLLAGG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHRTLQKDPKSPLKSYFQTVQVDLATYVTRFQWDRAKYPTAQPLKTLADIISKQVSQVDTELKSRRASYSHLKASIQSYERKSEGSLQNRLLTNIVKKEDLVLNSEYLTTLIVLVPRTEYVLWQKTYESMSKFVVPRSSRKLAEDAEAGVFTVTLFKSVIAEFKANAKKHKFTVREYNLEEAEKQ--KQKIGRLALDKKELCR----------------------------------------------TFVCWLKVNFSETFVAWIHVKVLRTFVESVLRYGLPVSFQAILLQPGKKN-VKHLKQQLNSLFKHLD------PAAISTKPEMGLDIPDGGAGQQEYYSYICYPIKINLVDPS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31412-1", "uniprot_id": "VATC_YEAST", "id": "P31412-1", "name": "V-type proton ATPase subunit C", "aln": "MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAFVSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPINN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLAAAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVVPASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDSAASLEQSLR----------------------------------------------VQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPPKN-LSKCKSELIDAFGFLGGNAFMKDKKGKINKQDTSLHQYASLVDTEYEPFVMYIINL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :** * : : : . . : **::*:*:** *: *::*.::* : : : : : . : . : :: .*:*: *: :.: : ::: *:: :::: *. * .: *::. *.* * * ::*. :.::*:**:* *::* *.: : **.::. :** *: : ** : : .* ** . :* *::.** *:: .* ::: ::. :: *. : :.* .*:*.**.:.********* *: :: *. .: :. * . : .*. : :* .:: : :. ", "identical_positions": 68, "similar_positions": 124, "identity": "7.59%" }, { "cls_id": "homologset.agr.SGD:S000001564", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FR6-1", "uniprot_id": "EF1G_RAT", "id": "Q68FR6-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQIRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRG--------STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----TERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQDLAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAVNQGKIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N0-1", "uniprot_id": "EF1G_MOUSE", "id": "Q9D8N0-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRG--------STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--TFQHVGKAVNQGKIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26641-1", "uniprot_id": "EF1G_HUMAN", "id": "P26641-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRG--------STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAFNQGKIFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE25-1", "uniprot_id": "EF1G_DANRE", "id": "Q6PE25-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDDGFCLFESNAIAHYLSNDVLRG--------STPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPA-EEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEG--EFKHVGKPFNQGKIFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJH0-1", "uniprot_id": "EF1G_DROME", "id": "Q9NJH0-1", "name": "Elongation factor 1-gamma", "aln": "MVKGTLYTYPENFRAYKALIAAQYSGAQVKVADN---FKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSESNAIAYLLANEQLRGG-------KCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNS--TAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPK-----EKKEAPKKAAEP-AEELDAADEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNED-EAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVWRGQDLAFTLSPDWQIDYEVYDWKKLDAKSEETKKLVTQYFSWSG--TDKD-GRKFNQGKIFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36008-1", "uniprot_id": "EF1G2_YEAST", "id": "P36008-1", "name": "Elongation factor 1-gamma 2", "aln": "MSQGTLYIN-RSPRNYASEALISYFKLDVKIVDLE---------QSSEFASLFPLKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDLHAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPKKQK----------------------------AEKPKAEKSKAEKKKDEAKPADDAAPAK-KPKHPLEALGKSTFVLDDWKRKYSNDDTRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDFAP--AFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAWDKPVVVNGEDKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** .. * : : .* ::: . ::. * ** :.**: .* : *: ** . ::*: . :*: :* *:*:.:::. . .:. *:: :*: . : : :: *. **:. *.::*.*: . : :* * * . : *** * . .:: . : **.** : . * : *: : * * :* . .: * .:: *.*.*: * *.:* :*::** ***:* . ::*:*::::: : :*:* *:: :**: .*** **: *:*:**. * *..: ::* :... * * : ***::* : * *:* * : *** .** : :* : ::*. : .: . :**::*", "identical_positions": 98, "similar_positions": 137, "identity": "21.63%" }, { "cls_id": "homologset.agr.SGD:S000001565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F149-1", "uniprot_id": "F7F149_RAT", "id": "F7F149-1", "name": "", "aln": "-----------------------------------------------------------------MSSTVRTKGSEAAG----PPKKKRKKTQNKSRKQEEKTMEHKTKPLGKKSPTSSSAKK-------------------PGLSKQG---SSGSLGSPEDSRGTAPDSVFALDFLRQRLHEKIQMARGQGGTKELSAATLEKRQRRKQERERKKRKRRELRAKQQVAEAEKK---EEPVKAPPKMACKDLQES------GLIFNKVEVAGEEPASKAQRKKEKRQQVKGNLTPLTGRNYRQLLDRLHARQGRVEELRDQ-DAGKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKARKKGRVLPQDLER--AGLS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70279-1", "uniprot_id": "SURF6_MOUSE", "id": "P70279-1", "name": "Surfeit locus protein 6", "aln": "-------------------------------------MASLLAKDTYLQDLAKKICAQPGPERQRSTWGVRTKGSEAAG----APKKKRKKTQKKSPEQEQKAMDHKTKALGKKPPTSSRPKN-------------------PMVSKQEK--GLSSLGSPKDSQGTARESVFALDFLRQRLHEKIQLARGQGSTKELSAATLEKRQRRKQERERKKRKRKERQAKQQVAEAEKK---EEPVEVTPKMACKELQES------GLIFNKVEVTEEEPASKAQRKKEKRQKVKGNLTPLTGRNYRQLLDRLQARQGRLDELRDQ-DAAKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKAHKKGRVLPQDLER--AGLS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75683-1", "uniprot_id": "SURF6_HUMAN", "id": "O75683-1", "name": "Surfeit locus protein 6", "aln": "-------------------------------------MASLLAKDAYLQSLAKKICSHSAPEQQARTRAGKTQGSETAG----PPKKKRKKTQKKFRKREEKAAEHKAKSLGEKSPAASGARR-------------------PEAAKEEAAWASSSAGNPADGLATEPESVFALDVLRQRLHEKIQEARGQGSAKELSPAALEKRRRRKQERDRKKRKRKELRAKEKARKAEEATEAQEVVEATPEGACTEPREPP-----GLIFNKVEVSEDEPASKAQRRKEKRQRVKGNLTPLTGRNYRQLLERLQARQSRLDELRGQ-DEGKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRRWEKRTAGVVEKMQQRQDRRRQNLRRKKAARAERRLLRARKKGRILPQDLER--AGLV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36080-1", "uniprot_id": "RRP14_YEAST", "id": "P36080-1", "name": "Ribosomal RNA-processing protein 14", "aln": "MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTKEQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSKVEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKKSITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLESEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARATSDLQRLRKAGRTKG----PAKNDVKSHLKLLEAKKNKMEAKDEL-EQIKQKEKE---KWQKAMLQAEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKDNKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDS6-1", "uniprot_id": "SURF6_DROME", "id": "Q9VDS6-1", "name": "Surfeit locus protein 6 homolog", "aln": "-----------------------------------------MTQAEIVKCLREEYEIEHNKDQKPEKEDLPAITKKFYQ------RVLELLTIHKVPYSKQEDEETYEEYLLSDTEESGNKKK-----------------------KQQG----KLKNQDSDDEDVEARIASIKNKLRQKKGPTTERQQKRRESKKLKRSKGVQKLLLSSAKNLKNENVKHQKLKNGVVKSEQETEDSKEQIQPVKVQPVYNQEAK------IVYSKVDFAAN-PGGKAKKSHQ---------------NPKEILKKLRDTKKHLTELREQGETDKAAEIQTDIAWRNAFDKVEGKKVKDDTKLLQKAIKKRRVEKKKSKTKWTERKQKVEHDKEKRQKKRQENLEKRSKDKKNRKLKTASKRGRIIPGY----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . . . :* .: : . . *: . : **.: . . : : : : :: .. :. *. : .. : :: . .. .. : :: :::.:: . . . : . : :. *. *. : :: : * * : * : : :.** *::** :**::*:*::. .: : .* :*. * . .:**.:*.:**. :. : ::: : : : ", "identical_positions": 27, "similar_positions": 101, "identity": "6.11%" }, { "cls_id": "homologset.agr.SGD:S000001568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04636-1", "uniprot_id": "MDHM_RAT", "id": "P04636-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPVGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLG--PEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VIECSFVQS---KETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08249-1", "uniprot_id": "MDHM_MOUSE", "id": "P08249-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPAGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLG--PEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VVECSFVQS---KETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40926-1", "uniprot_id": "MDHM_HUMAN", "id": "P40926-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPASAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLG--PEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VVECSFVKS---QETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEB1-1", "uniprot_id": "Q9VEB1_DROME", "id": "Q9VEB1-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLKQVTKQLALQGVRTFSVGQQNN-YKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIG--ADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKN--VIECSYVQS---TVTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKKNIQKGIDFANA---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17505-1", "uniprot_id": "MDHM_YEAST", "id": "P17505-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSRVAK-------RAFSSTVANP-YKVTVLGAGGGIGQPLSLLLKLNHKVTDLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKKLFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTNHKLMS-DDKRHELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERD--VIEPSFVDSPLFKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIEKGVNFVASK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VU29-1", "uniprot_id": "Q9VU29_DROME", "id": "Q9VU29-1", "name": "Malate dehydrogenase", "aln": "MFLASRLLSHVGNLPPKVQQLGYINRGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEG--KNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSKDECIVECAYVES---DVTEAQFFATPLILGPQGVKENTGLPDLDDEERKALNGMLPILKESIAKGIKLGEGMICSCA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU28-1", "uniprot_id": "Q9VU28_DROME", "id": "Q9VU28-1", "name": "Malate dehydrogenase", "aln": "MLLLTSLKS-----LAKPATWGVVVRTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMKGIATDLSHISQTGKVIGFTG--EKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGIAGQDG--LIECAFVAS---KLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEKLLPILRQNADEGVNFAKMILSGQSHSPIPAALP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : **:* *: ***********: : * *:*: *:..***** . . : . * ..:. *:*::.**:** *** *:.*. *. : :: : :: .* * : .*:**:* :* .* :: *.::..::**::*** :*: *:.. . .* .: *****:* **:*::** . * *** .* ***:** * ********.*.: *. ::: .: *. . ::* ::* * :*::*: ** .*::. : .: *.: : *: . :* .: ", "identical_positions": 98, "similar_positions": 104, "identity": "27.15%" }, { "cls_id": "homologset.agr.SGD:S000001569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D975-1", "uniprot_id": "SRXN1_MOUSE", "id": "Q9D975-1", "name": "Sulfiredoxin-1", "aln": "MG-----LRA--------GGALRRAG---------AGPGAPEGQGP-GGAQGGSIHSGCIATVHNVPIAVLIRPLPSVLDPAKVQSLVDTILADP--DSVPPIDVLWIKGAQGGDYYYSFGGCHRYAAYQQLQRET------IPAKLVRSTLSDLRMYLGASTPDLQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYN0-1", "uniprot_id": "SRXN1_HUMAN", "id": "Q9BYN0-1", "name": "Sulfiredoxin-1", "aln": "MG-----LRA--------GGTLGRAG---------AGRGAPEGPGPSGGAQGGSIHSGRIAAVHNVPLSVLIRPLPSVLDPAKVQSLVDTIREDP--DSVPPIDVLWIKGAQGGDYFYSFGGCHRYAAYQQLQRET------IPAKLVQSTLSDLRVYLGASTPDLQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX10-1", "uniprot_id": "SRX_DROME", "id": "Q9VX10-1", "name": "Sulfiredoxin", "aln": "MEFISHFLRATSRRTAALGPILQRNRSEIIQKQSLTNRQAFRRYRSSCSTMDTTVHSAGIDETHLVPMSVIQRPIPSVLDEQKVQSLMETIKNETSEDEVPPIDLLWISGSEGGDYYFSFGGCHRFEAYKRLQRPT------IKAKLVKSTLGDLYHYMGSSAPKYLA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36077-1", "uniprot_id": "SRX1_YEAST", "id": "P36077-1", "name": "Sulfiredoxin", "aln": "-------------------------------------MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTASKTCSLEQAEAAAS-AGELPPVDVLGVR-VKGQTLYYAFGGCHRLQAYDRRARETQNAAFPVRCRVLPATPRQIRMYLGSSLDIE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : .: .: .: *. ** :: . ..:**:*:* : :* :::****** **.: * * : .::: :* :: *:*:* ", "identical_positions": 22, "similar_positions": 36, "identity": "13.1%" }, { "cls_id": "homologset.agr.SGD:S000001571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6H7-1", "uniprot_id": "A0A8I6A6H7_RAT", "id": "A0A8I6A6H7-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTTPRSHRTKLRLPECHAITSFSLESFRAGKALDTAILGGILQLILLSSQKATRSRMEPEAPCPASIPSVER-------------------------KFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVTVVTTERAKHFYS--PQDVPVTLYSDADEWEMWKRRSD-------PVLHIDLRRWADLMVVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVG-QLKAFGYVEIP-CVSKKLVCGDQGLGAMAEVEIIVAKVKDVLFQHGGIQQS--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZB2-1", "uniprot_id": "COAC_MOUSE", "id": "Q8BZB2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKAPCPAAVPSEER-------------------------KFRVLVGVTGSVAALKLPLLVSKLLDVPG---LEVTVVTTERAKHFYS--PQDVPVTLYSDADEWEMWKRRSD-------PVLHIDLRRWADLMLVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVA-QLKAFGYVEIP-CVSKKLVCGDQGLGAMAEVETIVAKVQAVLSQHGSIQQS--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CD2-1", "uniprot_id": "COAC_HUMAN", "id": "Q96CD2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKASCPAAAPLMER-------------------------KFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVAVVTTERAKHFYS--PQDIPVTLYSDADEWEIWKSRSD-------PVLHIDLRRWADLLLVAPLDANTLGKVASGICDNLLTCVMRAWDRSKPLLFCPAMNTAMWEHPITAQQVD-QLKAFGYVEIP-CVAKKLVCGDEGLGAMAEVGTIVDKVKEVLFQHSGFQQS--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36076-1", "uniprot_id": "CAB3_YEAST", "id": "P36076-1", "name": "Coenzyme A biosynthesis protein 3", "aln": "MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIHDESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINTSMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQEEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDGTDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSANNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVATIKVPLIIDKLFKIYGPEKISIQLIVTKPAEHFLKGLKMSTHVKIWREEDAWVFDAVNKNDTSLSLNLILHHELRKWADIFLIAPLSANTLAKLANGICNNLLTSVMRDWSPLTPVLIAPAMNTFMYINPMTKKHLTSLVQDYPFIQVLKPVEKVLICGDIGMGGMREWTDIVEIVRRRINEIRKARDEETGDKEQEQEEQEGADNEDDDDEDDEEDEEDEEEEEALNETASDESNDEEDEEDEEDVKTEV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*. :: .: **::*:*.*****::*:**::.**:.: * :.: ::.*: *:** . . *.:: : * * : ..: :** :**:***::::***.****.*:*.***:****.*:* *. .*:*:.***** *: :*:* ::: :: : :::: * * *:*** *:*.* * ** *: : : ::. ", "identical_positions": 72, "similar_positions": 80, "identity": "12.61%" }, { "cls_id": "homologset.agr.SGD:S000001572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSW8-1", "uniprot_id": "E9PSW8_RAT", "id": "E9PSW8-1", "name": "Centromere protein C", "aln": "MASFHLDHLKN-YHRRFCRPSRAPNIPTKQGQNMLEILQDCFEEQ--------NSTESLSCSTPKEKDIYVQSTGKERQASHSESVPISSRRKEASLQVPAKPSDPADEPVQANEVHQKILSTDVVSKSTPDSTKTSSKGVKGHHGASD-ELYLPGGSPVVLLGARVSGSQKAISSGGQKRVT--SRRSADMQSSNTDIPFKTRKRLNFEDKVISNTAEIESSASQVEDSISEEQEGTSSETSQKRD-DLSSEIQPQSKKSFSELYLETVNRKSKCSSVVRHTAAVPSPPYPPNDMKLLEDEFIIDGPDRSFSSQPWVVIPRK----GHHMPFP-ENIAVPQGKKSREKPHRLSEKTLVSNTQTDKTGPVEEAQLSVEEKLGT--TLTNEVENDCRSTENKTHSENAKKPSARKRTVKQKQRRPSKPN-VAQELSMGQNETENRNMSKIGQDKLQINSKRNMEDHEEVRNEPTPKKPVPALGNKKEKDSTQANKEKSRKKCFSRESKRKSVPKEVTLASRRGRRTSQHPSEWWLVKPSEGSVDGNSSKENESSILYPNRKKQTKR-NHVSENTEKKPVPSKRKKKEIS--SRELKSLNVKGSG----GNDDIST-SQRKPLQNIDADPT-QKSLHCSGPTRGSEDQNSDMISQNVHLKTRSEQHRSKTQMESTSNSEVCKHSVWEESGPSRFKN-LEMPGRSNSEVGDEKDQKSLDLKTRSSNMVPNRNLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERIDYQESSSGRLVLE-IVSPASESVKRKAKRNLDKVNKETNKKRIHLDN-PTKTKIKVSLDIPLGDPFQATLAKDPETREIVPMDLIRPRDTYHFFVEQHGLKVYKTLNTTFFSTGKLVLGPHEEKGKQHVGQDILVFYVNFGDLLCTLHETPYMLTTGDSFYVPSGNHYNIKNLLNVESCLLFTQIKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49452-1", "uniprot_id": "CENPC_MOUSE", "id": "P49452-1", "name": "Centromere protein C", "aln": "MASFHLDHLKN-YHRRYCRSSRAPNIHTKKGQNMLEILQDCFEDQSKA-SFLDDFTESLTSSTQKKKANYSQSSSKKCPESHSKPVPVSSRTGEASLQASAEPSEAAGGSVQANEVH---------------------------HGASD-ELDLCVGSPVVLLDANVNTLQKAASPAGQKRVASVSRSPVDRQASNKNISFKTRKRLNFEDKVTLSTAETENSVLQVEDNLSKGQEGTSSEITQKRD-DLSSDVQSRSKKNFSELFLETVKRKSKSSSVVRHTAAVPFSPPPPSDMKLLEDEFIIDRSDRSFSSRLWVMIPSKDRHLSAHKPSP-ENTALLQGKKSREKSHSLSAMTFARNTQSDKAHPIEEAQLSVEENPAT--TCTDELENDCRSPENKMQSETAKTPPAWERTTKQSQRRVSKPK-AAEELRKGQSSWENSNVSNTGQDKLQINSKRNMKDCEEVRNEPNPKKQKPALENKKKTNSTQTNKEKSGKKFFSGGSKNKFVPKKVTLTSRRSCRISQRPSEWWRVKSDESSVDRNPSKENNSPVVYPNKKKQTKR-NHVSKRAGKKPGSSKRQKTEMS--PRVQKSLNVKDSGGTVSGHDDTSR-SQRKPLKIIEADPT-QKSLAISRPKRGCKYRNNVMTSPNVHLKSHTEEYTSKTQMESASNSEMSKRSVWEESGPSRFKN-YEMPGSSNSEMGDEQDQKSLHFTTRSFNMVPDKKLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERVDYQESSSGQLVLE-IISPSSVPTKIKAQRNLGKVNKKVTKKPTHLNS-HEKAKMELPLDMRLGDPFQATLAKDPETAELVPMDLIRPRDTYRFFVEQHGLKVFKTLDTIYFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGDLLCTLHETPYKLTTGDSFYVPSGNHYNIKNLLNVESSLLFTQIKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03188-1", "uniprot_id": "CENPC_HUMAN", "id": "Q03188-1", "name": "Centromere protein C", "aln": "MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKK--SSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGG-IVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGK--NDVDDEEVHGSSDDSKQS-KVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDLVRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35201-1", "uniprot_id": "CENPC_YEAST", "id": "P35201-1", "name": "Inner kinetochore subunit MIF2", "aln": "-----MDYMKLGLKSRKTGIDVKQDIPKD--EYSMENIDDFFKDD-------ETSLISMRRKSRRKSSLFLPSTLNGDTKNVLPPFLQSYKSQ--------------------------------------------------------------------------------------------------------------------------------------DDEVVQSPSGKGDG--------------------------------SRRSSLLSHQSNFLS---PANDFEPIEEEPEQEEND-------------------------------------------IRGNDFATPITQKLSKPTYKRKYSTRYSLDT------SESPSVRLTPDRITNKNVYSDVPDLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESEEDGDYIESDSSLDSGSDSASDSDGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTDSIIDRNG---LRKSTRVKVAPLQYWRNEKIVYKRKSNKPVLDIDKIVTYDESEDEEEILAAQRRKKQKKKP------------------------------------TPTRPYNYVPTGRP------RGRPKKDPNAKENLIPED------PNEDIIERIESGGIENGEWLKHGILEAN-----------------------------------VKISDTKEETKDEIIAFAPNLSQTEQVKDTKDENFA---LEIMFDKHKEYFASGILKLPAISGQK----------KLSNSFRTYITFHVIQGIVEVTVCKNKFLSVKGSTFQIPAFNEYAIANRGN-DEAKMFFVQVT----------------------VSEDANDDNDKELDSTFDTFG----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::* : * . :* .. : :* ::* *::. *: .: : . *. : . .. * : :*. : . . . *. *.:: * : *..* : :*:* : * : :. . . * : * . * . . * . . .:.. . : ::.: * . . :: :. :: .. :* :*. .:.. .: .: .: : .: .:. :.: :: . . . : .: :. * . * ::* : * . : : . :. :. ... :* . : .* : :. . . ..:. : .:. : .. . . :. * .: * . :.. . . * : : :**: :::: : . * : :: . . ::. : . : * .. : : : : : ..: : : * * : . :: ***: .*..::. .::: : .** ", "identical_positions": 47, "similar_positions": 203, "identity": "4.95%" }, { "cls_id": "homologset.agr.SGD:S000001574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQG0-1", "uniprot_id": "A0A8I5ZQG0_RAT", "id": "A0A8I5ZQG0-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPTGPSSETCSSS-KNQAASAAVLVPDAAAVKEGLSGEVLSSPGTVAEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQ--------VLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGL-RRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTPEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDAASVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSHSSSMISSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8Y5H7-1", "uniprot_id": "S14L1_MOUSE", "id": "A8Y5H7-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGALHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPVGPS-ETCSSS-KNQVTSAAVLVPDAAAVMEGLSGENLSSPGTASEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQ--------VLLDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGL-RRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTAEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSQSSSMISR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92503-1", "uniprot_id": "S14L1_HUMAN", "id": "Q92503-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCKLDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWSPPSITTSSETSSSSSKKQAASMAVVIP-EAALKEGLSGDALSSP-SAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQ--------VLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGL-RRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCEVPEGGLVPKSLYRTAEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSHSSSMISR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O43304-1", "uniprot_id": "S14L5_HUMAN", "id": "O43304-1", "name": "SEC14-like protein 5", "aln": "MVQRYQSPVRVYKYPFELVMAAYEKRFPTCPQIPVFLGSEVLRESRSPDGAVHVVERSCRLRVDAPRLLRKIAGVEHVVFVQTNILNWKERTLLIEAHNETFANRVVVNEHCSYTVHPENEDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRGKEVIEHYLNELISQGTSHIPRWTPAPVREEDARNQAG---------------PRDPSSLEAHGPRSTLGPALEAVSMDGDKLDADYIERCLGHLTPMQESCLIQLRHWLQETHKGK-IPKDEHILRFLRAHDFHLDKAREMLRQSLSWRKQHQVDLLLQTWQPPA--------LLEEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLRHVLSVNEEGQ-KRCEGSTRQLGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFLIYSGSNYQGPGGLVDYLDREVIPDFLGGESVCNVPEGGLVPKSLYMTEEEQEHTDQLWQWSET-YHSASVLRGAPHEVAVEILEGESVITWDFDILRGDVVFSLYHTKQAPRLGARE----PGTRASG----QLIDKGWVLGRDYSRVEAPLVCREGESIQGSHVTRWPGVYLLQWQMHSPPSSVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCTSGFSQLSAATSSSSSGQSHSSSLVSR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A8B0-1", "uniprot_id": "D4A8B0_RAT", "id": "D4A8B0-1", "name": "", "aln": "MVQKYQSPVRVYKYPFELVMAAYEKRFPTCPLIPVFLGSEVLSECRSADGAVHTVERSCRLRVDAPRLLRKIAGVEHVVFIQRNVLNWRERTLLIDAHNETFASRVTVKEHCRYTVHPENEDWTCFEQSASLDVRSFFGFESTLEKIAMKQYTANVKRGKEVIEHYLSELISQGASHIPRWTPAPVREADVRSQLV---------------CPCPSSLETDGPSDAPAPASEMATADGDKLDADYIERCLGHLSPMQESCLVQLRRWLQETHKGK-IPKDEHILRFLRARDFHLDKARDMLCQSLSWRKQHQVDLLLQTWRPPA--------PLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLQHVLSVNEEGQ-KRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGESVCNVPEGGMVPKSLYLTEEEQEQADQLRQWSET-YHSASVLRGSPHEVAMEIPEGESVITWDFDILRGDVVFSLYHAKQAPKLSPQE----PGVRASG----QLIDKNWILGVDYSRVEAPLICREGQSIQGSHVTQWPGVYLLQWQIHSPPESVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCASRFSQLSATTTSSSSGQSHSGSMVSR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0F9-1", "uniprot_id": "S14L4_MOUSE", "id": "Q8R0F9-1", "name": "SEC14-like protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGQVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQILT-WQAPE--------VIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQDMIRKRIKVCEMLL-HECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILG-GNWKQE--LVKFVSPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKRYYLSNQERPQYEHSVVVGRGSSHQVENEILFPGCVLRWQFASDGGDIGFGVFLKTR-------------------------MGERQKAGEMVEVLPSQRYNAHMVPEDGSLNCLKAGVYVLRFDNT--------------------YSLLHTKKVGYTAEVLLPD---------KACEEKLQGLGSVSPP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDX3-1", "uniprot_id": "S14L4_HUMAN", "id": "Q9UDX3-1", "name": "SEC14-like protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIVT-WQPPE--------VIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLL-HECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILG-DNWKQE--LTKFISPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTK-------------------------MGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNT--------------------YSRMHAKKLSYTVEVLLPD---------KASEETLQSLKAMRPSPTQ------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5MCN3-1", "uniprot_id": "S14L6_HUMAN", "id": "B5MCN3-1", "name": "SEC14-like protein 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGQVGDLSPSQEKSLAQFRENIQDVLSALPNPDDYFLLRWLQARSFDLQKSEDMLRKHMEFRKQQDLANILA-WQPPE--------VVRLYNANGICGHDGEGSPVWYHIVGSLDPKGLLLSASKQELLRDSFRSCELLL-RECELQSQKLGKRVEKIIAIFGLEGLGLRDLWKPGIELLQEFFSALEANYPEILKSLIVVRAPKLFAVAFNLVKSYMSEETRRKVVILG-DNWKQE--LTKFISPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKSYYLCKQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTK-------------------------MGERQRAREMTEVLPSQRYNAHMVPEDGILTCLQAGSYVLRFYNT--------------------YSLVHSKRISYTVEVLLPD---------QTFMEKMEKF---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SQ27-1", "uniprot_id": "Q5SQ27_MOUSE", "id": "Q5SQ27-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILD-WQPPE--------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERIL-HECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLGSNSWKEG--LLKLISPEELPAHFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQKAGEMVEVLTSQRYNAHMVPEDGSLTCSEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDEELTPV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1J8-1", "uniprot_id": "S14L3_RAT", "id": "Q9Z1J8-1", "name": "SEC14-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILD-WQPPE--------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERIL-HECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLG-NSWKEG--LLKLISPEELPAHFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQKAGEMTEVLTSQRYNAHMVPEDGSLTCTEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDEELTPI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UDX4-1", "uniprot_id": "S14L3_HUMAN", "id": "Q9UDX4-1", "name": "SEC14-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILD-WQPPE--------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERIL-HECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLG-NNWKEG--LLKLISPEELPAQFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDKELTPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99J08-1", "uniprot_id": "S14L2_MOUSE", "id": "Q99J08-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQEEALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS-WQPPE--------VIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLL-QECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLG-ANWKEV--LLKHISPDQLPVEYGG-TMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHTVQVSRGSSHQVEYEILFPGCVLRWQFMSEGSDVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHMVPEDGTLTCSEPGIYVLRFDNT--------------------YSFIHAKKVSFTVEVLLPD---------KAAEEKMNQQGADTPK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MS0-1", "uniprot_id": "S14L2_RAT", "id": "Q99MS0-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQEEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS-WQPPE--------VIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLL-QECTQQTAKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLG-ANWKEV--LLKHISPDQLPVEYGG-TMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSEGSDVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHMVPEDGTLTCSEPGIYVLRFDNT--------------------YSFIHAKKVSFTVEVLLPD---------KAAEEKLNQQGAVTPK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76054-1", "uniprot_id": "S14L2_HUMAN", "id": "O76054-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIIS-WQPPE--------VIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLL-QECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLG-ANWKEV--LLKHISPDQVPVEYGG-TMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNT--------------------YSFIHAKKVNFTVEVLLPD---------KASEEKMKQLGAGTPK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33324-1", "uniprot_id": "YKJ1_YEAST", "id": "P33324-1", "name": "CRAL-TRIO domain-containing protein YKL091C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDS-TLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYH-VLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILG-SSYKKE--LLKQIPIENLPVKYGG-------------------------TSVLHNPNDKFYYSDIGPWRDPRYIGPEGEIPN--------------IFGKFTVTS-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.*: * . * ::* : : .. :**:*:*:.*.:. : :: . :*: :: : : . * :* *:: :* :: * : :: ::: . * . : * :. : . :*:.: . :: :. . : *** : : ::::. *.. :.::..::. * *..: . .:: * . : : :* .* : . : : *. : . ", "identical_positions": 29, "similar_positions": 96, "identity": "3.97%" }, { "cls_id": "homologset.agr.SGD:S000001575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PW37-1", "uniprot_id": "E9PW37_MOUSE", "id": "E9PW37-1", "name": "", "aln": "-----------------------------------------------------------------------MELSPSSGGAAEALSWPEMFTG----------------------------LESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVF-----------DVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEMPVEGQDQ-QTDSTKGRCLRRTVSVPSEGQFPEYPQE-GTTKLEVPAERSPRRRSISGTSTSEKPNSMDT---ANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFR---LPSLRNAD--------DRSRGLPKLKESR----------------SHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSK-CFSCSSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKK----YFCELCLDDTLFARTTSKTK---ADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKK-DKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLI--------------FRENTIATKSIEEYLKLVGQQYLHDALG--EFIKALYESDENCEVDPSKCSSSE-------LMDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSG-SLSSGLQRICEDPTDS----------------DLHKLKSPSQD---------NTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNG-RSISLMDLQDTHAAQAEHASVMLDVP---MRLAGSQLSITQVAS------------IKQLRETQSTPQSAPQVRRPLHPALNQP-GSLQPLSFQNPVYHLN---------------NPVPAMPKASADSSLE--------NLSTASSRSQSNSEDFKLSGP-------------SNSSMEDFTKRSSHSED----FSRRHTVPDRHIP----LALPR--QNSTGQSQIRKLDHSGLG-------ARAKAPPSLPHSAS----------------LRSTGSMSVASAALMAEP-------------VQNGSRSRQQSSSSR-ESPVPKV-------------------------RAIQRQQTQQVQSPVDSATMSPVERTAAWVL-NNGQYEEDV-----------EETEQNQDE--AKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKS---IIS-----------------------------------------------------RLMAVEEELKKDHAEMQAVIDA-KQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSS-C", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABU3-1", "uniprot_id": "A0A8I6ABU3_RAT", "id": "A0A8I6ABU3-1", "name": "", "aln": "-----------------------------------------------------------------------MELSPSSGGAAEALSWPEMFSG----------------------------LESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVF-----------DVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEIPVDGQDQ-QADSTKGRCLRRTVSVPSEGQFPEYPPE-GTAKLEVPAERSPRRRSISGTSTSEKPNSMDT---ANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFR---LPSLRNAD--------DRSRGLPKLKESR----------------SHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSK-CFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKK----YFCELCLDDTLFARTTSKTK---ADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKK-DKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLI--------------FRENTIATKSIEEYLKLVGQQYLHDALG--EFIKALYESDENCEVDPSKCSSSE-------LTDHQSNLRMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDLSERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDK-------ATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSG-SLSSGLQKIFEDPTDS----------------DLHKLKSPSQD---------NTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNG-RSISLMDLQDTHTAQVEHGSVMLDVP---MRLAGSQLSITQVAS------------IKQLRETQSTPQSAPQVRRPLHPALNQP-GSLQPLSFQNPVYHLN---------------NPVPAMPKASADSSLE--------NLSTASSRSQSNSEDFKLSGP-------------SNSSMEDFTKRSSHSED----FSRRHTAPDRHIP----LALPR--QNSTGQSQIRKLDQSGLG-------ARAKAPPSLPHSAS----------------LRSTGSMSVASAALVAEP-------------VQNGSRSRQQSSSSR-ESPVPKV-------------------------RAIQRQQTQQVQSPVDSATMSPVERTAAWVL-NNGQYEEDV-----------EETEQNQDE--AKHAEKYEQEISKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKS---IISRLEDHLLSGEERKEKAITIKEVSCKETQAVSSSFSVSSSPVFVSTDTFFPPHSRLMAVEEELKKDHAEMQAVIDA-KQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSS-C", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJF2-1", "uniprot_id": "NGAP_HUMAN", "id": "Q9UJF2-1", "name": "Ras GTPase-activating protein nGAP", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTPEVPAERSPRRRSISGTSTSEKPNSMDT---ANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFR---LPSLRSTD--------DRSRGLPKLKESR----------------SHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSK-CFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKK----YFCELCLDDTLFARTTSKTK---ADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKK-DKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLI--------------FRENTIATKSIEEYLKLVGQQYLHDALG--EFIKALYESDENCEVDPSKCSSSE-------LIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSG-SLSSGLQKIFEDPTDS----------------DLHKLKSPSQD---------NTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNG-RSVSLMDLQDTHAAQVEHASVMLDVP---IRLTGSQLSITQVAS------------IKQLRETQSTPQSAPQVRRPLHPALNQP-GGLQPLSFQNPVYHLN---------------NPIPAMPKASIDSSLE--------NLSTASSRSQSNSEDFKLSGP-------------SNSSMEDFTKRSTQSED----FSRRHTVPDRHIP----LALPR--QNSTGQAQIRKVDQGGLG-------ARAKAPPSLPHSAS----------------LRSTGSMSVVSAALVAEP-------------VQNGSRSRQQSSSSR-ESPVPKV-------------------------RAIQRQQTQQVQSPVDSATMSPVERTAAWVL-NNGQYEEDV-----------EETEQNLDE--AKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKS---IIS-----------------------------------------------------RLMAVEEELKKDHAEMQAVIDA-KQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSS-C", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIR4-1", "uniprot_id": "A0A8M2BIR4_DANRE", "id": "A0A8M2BIR4-1", "name": "", "aln": "MSLTRLATLEEQTGSNRSPSRSSFGKDSVRRWRLLNRPWLKHRSNSAPEEPLDMHDRRILVRQDMRTQSLTWSRSSSTRPSNPPISRVHSLPDPQRVTSRGVLLEHANLQKDWLSRSSSPFFKSTSELGSEIHTGAPPLRRVSSSHMFSGILLSMSRRISRILNTSPEPAVGELSEDDVKGPASHHFSCGQSPFTEPCVWERKYCILTDSQLILLNKEEEMPSEVHESPSASSSKGRSLRRTVSVPSEGPFPDFPPEGASMIAEASAERSPRRRSISGLGSSEKNISIDG---PNSSPFKVPGFLSKRLKGSIKRTKSQTKLDRNTSFR---LPSLRPTEN-------DRSRGLPKLKESC----------------SHESLLSPGSAVEALDLSMEEDVYIKPLHSSILGQDFCFEVAYSGGSK-CFSCSSAAERDKWMENLKRTVQPNKDNCRRAENVLRLWIIEAKDLPPKKK----YFCELCLDDMLYARTTSKTR---SDCLFWGEHFEFSGLPSMKSITIHIYRDVDKKKKK-DKNNYVGLVNIPVHGVMGRQFVEKWYPVSTPTT--------------------SKAKGGGPSIRIKSRFQTISILPMEQYKEFAEFVTNNYTMLCSVLEPVISVKNKEE-----MASALVHILQSTGRAKDFLTDLVMSEVDRCADHDVLI--------------FRENTLATKAIEEYLKLVGQKYLHDALG--EFIKALYESDENCEVDQSKCTSNE-------LPEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCHARGKQDISQRLIS---ASLFLRFLCPAIMSPSLFGLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWAGMTRFLLEISNLETISNTPGFEGYIDLGRELSVLHSLLWEVVSQLDKGDNSFLQATVAKLGPLPRILGDITRSLSSPTPIQQQLRRFQDHSSAHDISG-SVSSGLQRIFEDPADS----------------EMRSIKSPVQE---------HMEALVRGKHPLLGQQSSAHSMSFSDKEERDSPLPNG-RSISLMDLQDSYLAQGHPGPNSLNEASSRLGRVGSQASIGPVPPPHLHQPPVH---PKVPQLRDNLPQSAPQVRRPIHPSLSQQ-RSLQPLSFQNPVYHLSNLHAQSTH-----STQSTHSAQSLQPDSSSE--------NLSTGSSRSASPSASGGRGATPRARIPS------TSSVEEEFSRRSIQGQETPPPTARWHPPLADQHSGAQVVAVPR--QSTTGTAHIVKVEQQSRGVGLVAANAGARTPRSLPHSTS----------------IRSG------SSANTEPI-------------QQSGERSRQQSTCSK-DGSVPGG-------------------------RAN-----KQVQSPVESVTMSPVERTAAWVL-NNGQYEDEE-----------EEG-QSKDD--AKHVEKYEQEISKLKERLRTSSRRLEEYERRLLAQEQQMQKLLLEYKTRLEDSEDRLRRQQEEKDSQMKS---IIC-----------------------------------------------------RLMAVEEELKRDHAEMQAVIDA-KQKIIDAQEKRISSLDAANSRLMSALTQVKERYSMHNLRNGLSPTNPTKLSITENGEFKNSS-C", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UHC7-1", "uniprot_id": "DAB2P_MOUSE", "id": "Q3UHC7-1", "name": "Disabled homolog 2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAGG----------------------------------NARKSTGRPSYYYRLLRRPRLQRQRSRSRSRT--RPARESPQERPGSRRSLPGSMSEK-NPSMEP---SASTPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFR-HILPGFRSAAAAAA--DNERSHLMPRLKESR----------------SHESLLSPSSAVEALDLSMEEEVIIKPVHSSILGQDYCFEVTTSSGSK-CFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKK----YLCELCLDDVLYARTTSKLK---TDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKK-ERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP--------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEE-----MASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLI--------------FRENTLATKAIEEYLKLVGQKYLQDALG--EFIKALYESDENCEVDPSKCSSAD-------LPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLIS---ASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQ-------SVVSKLGPLPRILRDVHTALSTPG--SGQLPGTNDLASTPGSGSSSVSAGLQKMVIENDLSGL-------------IDFTRLPSPTPE---------NKDLFFVTRSSGV-QPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPDALP----ADGQVPATQLLAGWPARAAPV---SLAGLATVRRAVPTPTTPGTSEGAPGRP-QLLAPLSFQNPVYQMAAG-------------LPLSPRG--LGDSGSE--------GHSSLSSHSNSEELAAAAKLGSFS------------TAAEELARRPG-------ELARRQMSLTE--KGGQ-PTVPR--QNSAGPQ--RRIDQPPPPPPPPPPAPRGRTPPTLLSTLQ----------------YPRPSSGTLASASPDWA---------------GPGTRLRQQSSSSKGDSPELKP-------------------------RAMH----KQGPSPVS---PNALDRTAAWLLTMNAQLLEDEGLGPDP---PHRDRLRSKEE--LSQAEK---DLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKG---IIS-----------------------------------------------------RLMSVEEELKKDHAEMQAAVDS-KQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQ-ARNGVSPTNPTKLQITENGEFRNSSNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P730-1", "uniprot_id": "DAB2P_RAT", "id": "Q6P730-1", "name": "Disabled homolog 2-interacting protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKK----YLCELCLDDVLYARTTGKLK---TDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKK-ERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP--------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEE-----MASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLI--------------FRENTLATKAIEEYLKLVGQKYLQDALG--EFIKALYESDENCEVDPSKCSAAD-------LPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLIS---ASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQ-------SIVSKLGPLPRILRDVHTALSTPG--SGQLPGTNDLASTPGSGSSSVSAGLQKMVIENDLSGL-------------IDFTRLPSPTPE---------NKDLFFVTRSSGV-QPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPEALP----ADGQVPATQLVAGWPARAAPV---SLAGLATVRRAVPTPTTPGTSEGAPGRP-QLLAPLSFQNPVYQMAAG-------------LPLSPRG--LGDSGSE--------GHSSLSSHSNSEELAAAAKLGSFS------------TAAEELARRPG-------ELARRQMSLTE--KGGQ-PTVPR--QNSAGPQ--RRIDQPPPPPPPPPPAPRGRTPPTMLSTLQ----------------YPRPSSGTLASASPDWA---------------GPGTRLRQQSSSSKGDSPELKP-------------------------RALH----KQGPSPVS---PNALDRTAAWLLTMNAQLLEDEGLGPDP---PHRDRLRSKEE--LSQAEK---DLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDVQMKG---IIS-----------------------------------------------------RLMSVEEELKKDHAEMQAAVDS-KQKIIDAQEKRIASLDAANARLMSALTQLKERYSMR-ARNGVSPTNPTKLQITENGEFRNSSNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VWQ8-1", "uniprot_id": "DAB2P_HUMAN", "id": "Q5VWQ8-1", "name": "Disabled homolog 2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAGG----------------------------------SARKSTGRSSYYYRLLRRPRLQRQRSRSRSRT--RPARESPQERPGSRRSLPGSLSEK-SPSMEP---SAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFR-HILPGFRSAAAAAA--DNERSHLMPRLKESR----------------SHESLLSPSSAVEALDLSMEEEVVIKPVHSSILGQDYCFEVTTSSGSK-CFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKK----YLCELCLDDVLYARTTGKLK---TDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKK-ERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP--------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEE-----MASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLI--------------FRENTLATKAIEEYLKLVGQKYLQDALG--EFIKALYESDENCEVDPSKCSAAD-------LPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLIS---ASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLEQ-------SIVSKLGPLPRILRDVHTALSTPG--SGQLPGTNDLASTPGSGSSSISAGLQKMVIENDLSGL-------------IDFTRLPSPTPE---------NKDLFFVTRSSGV-QPSPARSSSYSEANEPDLQMANGGKSLSMVDLQDARTLDGEAGSPAGPDVLP----TDGQAAAAQLVAGWPARATPV---NLAGLATVRRAGQTPTTPGTSEGAPGRP-QLLAPLSFQNPVYQMAAG-------------LPLSPRG--LGDSGSE--------GHSSLSSHSNSEELAAAAKLGSFS------------TAAEELARRPG-------ELARRQMSLTE--KGGQ-PTVPR--QNSAGPQ--RRIDQPPPPPPPPPPAPRGRTPPNLLSTLQ----------------YPRPSSGTLASASPDWV---------------GPSTRLRQQSSSSKGDSPELKP-------------------------RAVH----KQGPSPVS---PNALDRTAAWLLTMNAQLLEDEGLGPDP---PHRDRLRSKDE--LSQAEK---DLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKG---IIS-----------------------------------------------------RLMSVEEELKKDHAEMQAAVDS-KQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQ-ARNGISPTNPTKLQITENGEFRNSSNC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZX5-1", "uniprot_id": "A0A8M6YZX5_DANRE", "id": "A0A8M6YZX5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MFGGPTPISPHIT-----------RCQHQGWMRVT-----------DMKGSSVHWLSCGQP-LSEPIGWQVKFCLVAECQLVLLDKREISPLLFQERRAESCTVWLLRRSTSIPEGVQLRKDQSTQ--TRNTKSLADRVGRRRSMPGSTVDKTVVAMDA---DTSTPFKVTGFLSRRLKGSIKRTKSQPKLDRHSSFR-NILPGFKSAE------NDSRSHLMPRLKESR----------------SHESLLSPSSAVEALDLSMEEEVLIKPVHSSILGQDFCFEVTTSTGSK-CFSCRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKK----YFCELCLDDTLYARTTCKLK---TDNVFWGEHFEFNNLPSVKSITVHLYKETDKKKKK-DKNNYVGLVNIPIATVTGRQFVEKWYSVSTPNP--------------------NKGKSPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEE-----MACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLI--------------FRENTLATKAIEEYLKLVGQKYLQDALG--EFIKALYESDENCEVDPSKCSSSD-------LHEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLIS---ASLFLRFLCPAIMSPSLFSLMQEYPDDRTARTLTLIAKVTQNLANFTKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETISNTAGFEGYVDLGRELSSLHSLLSEAVSQLDQ-------TTITKLGPLARILRDVNSALTNPT--GAPVPSPTERVGSPSLPSSSLSTGLQKMVMDSEITGL-------------VDFTRLPSPTPE---------NKDLFFVTRNSVI-QPSPARSSSYSEANEPDVQIPNGSKSLSMVDLQDSRSLESAANTSFSDPIN------DSQASAGQSAGMWTTRTIKG---NTPSGPTLRRAGQTPTTP-STESAPGRS-QLLAPLSFQNPVYQMAAG-------------LPVSPRA--VADSGSE--------CQSSIS--SNAEEAATAGPKHPFISQSSTGASGGGGSSGDEFIQRPG-------EFTRRQLSLTE--TQHQ-TNVPR--QNSAGPQ--RRIDQPPP------AITRGRTPPNMLNTAP----------------YPRPSSGSMMSSSPDWP---------------SSGTRLRQQSSSSKGDSPESKQ-------------------------RTLH----KQAPSPVN---PNALDRTAAWLLNMNVQYLEQEGIDPDS---KHREDFPNKED--LTPTEKYQHEIAVLQEKLRISAKKLEEYESRMKSQDDQTQKMLLEYQARLEDTEERLRKQQDDKELQMKS---IIT-----------------------------------------------------RLMSVEEELKKDHSDMQAIVDS-KQKIIEAQEKRIASLDAANARLMSALSQLKDRYSMQ-TRNGISPTNPTKLQITENGEFRNSSNC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5PF31-1", "uniprot_id": "A5PF31_DANRE", "id": "A5PF31-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSG------------------------------------VTRKGSGRPGYYYRLLGRTRLQRQRSRSRSRSRVTNNKDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFR-HILPGFRPVD-------NERSHLMPRLKESR----------------SHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSK-CFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKK----YFCELCLDDSLYARTTCKMK---TDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKK-DKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNP--------------------GKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEE-----MACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLI--------------FRENTLGTKAIEEYLKLVGQKYLQDALG--EFIKALYESDENCEVDPSKCSSSD-------LPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLIS---ASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQ-------SAASKLGPLPRILRDVHGALTNPT--NVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGP-------------VDFTRLPSPTPE---------NKDLFFVTRSSGL-QGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAG---------ITSEGMGEGAMVPWNARTPQG---NIAGGPTLHRPVQSPTTP-GAEGAPGRPTQLLAPLSFQNPVYQMAAG-------------LPVSARGNASGDSGSE--------CHSSVSSHSNNEECLGGTKTTFLTQG---------ASVGEEFARRSG-------DFSRRQLSLTDPQHGNQ-PTVPR--QSSAGPQ--RRIDQPPPP---TQTAPRGRTPPNLLNSGP----------------YPRPLNNTMMSSSPDWP---------------GSGARLRQQSSSSKGDSPETKH-------------------------RAPH----KQAPSPVN---PSALDRTAAWL--MNVPYIEQE-----------PETELCRDE--HTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKG---IIS-----------------------------------------------------RLMSVEEELKKDHADMQAVVDS-KQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQ-TRNGISPTNPTKLQITENGEFRNSSNC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6SEU4-1", "uniprot_id": "SYGP1_MOUSE", "id": "F6SEU4-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSRSRASIHRGSIPAMSYAPFR-----------------DVRGPPMHRTQYVHSPYDRP-GWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESS-RNKLLRRTVSVPVEGR---------PHGEHEYHLGRSRRKSVPGG----KQYSMEAAPAAPFRPSQ--GFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSADH-------DRARLMQSFKESH----------------SHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTK-CFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKR----YYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKK-DKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEE-----VASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLI--------------FRENTLATKAIEEYMRLIGQKYLKDAIG--EFIRALYESEENCEVDPIKCTASS-------LAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLIS---ASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSK-------EALLKLGPLPRLLNDISTALRNPNIQRQPSRQS-ERTRSQPMVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSR-PPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLT--AALGLRPAPAG-RLSQGSGSSITAAGMRLSQMGVTTDG-VPAQQLRIPLSFQNPLFHMAADGPGPPAGHGGSSGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPK--PPAAS----ILHSHSYSDEFG-PSGTD------FTRRQLSL--QDSLQHMLSP---PQITIGPQRPAPSGPGGGSGGGSGGG---QPPPLQRGKSQ---QLTVSAAQ-----KPRPSSGNLLQSPEPSYG----------------PARPRQQSLSKEGSIGGSGGSGGGGGGG----------------LKPSITKQHSQTPSTLN-PTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQVEKDSQIKS---IIG-----------------------------------------------------RLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAP--P------APPPPPRLQITENGEFRNTADH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PV0-1", "uniprot_id": "SYGP1_HUMAN", "id": "Q96PV0-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSRSRASIHRGSIPAMSYAPFR-----------------DVRGPSMHRTQYVHSPYDRP-GWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESS-RNKLLRRTVSVPVEGR---------PHGEHEYHLGRSRRKSVPGG----KQYSMEGAPAAPFRPSQ--GFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSADH-------DRARLMQSFKESH----------------SHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTK-CFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKR----YYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKK-DKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEE-----VASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLI--------------FRENTLATKAIEEYMRLIGQKYLKDAIG--EFIRALYESEENCEVDPIKCTASS-------LAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLIS---ASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSK-------EALLKLGPLPRLLNDISTALRNPNIQRQPSRQS-ERPRPQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSR-PPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLT--AALGLRPAPAG-RLSQGSGSSITAAGMRLSQMGVTTDG-VPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPK--PPAAS----ILHSHSYSDEFG-PSGTD------FTRRQLSL--QDNLQHMLSP---PQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQ---QLTVSAAQ-----KPRPSSGNLLQSPEPSYG----------------PARPRQQSLSKEGSIGGSGGSGGGGGGG----------------LKPSITKQHSQTPSTLN-PTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKS---IIG-----------------------------------------------------RLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAP--P------APPPPPRLQITENGEFRNTADH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5U5-1", "uniprot_id": "A0A8M2B5U5_DANRE", "id": "A0A8M2B5U5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MSYVSSQDGRCVSPCSRPHT-----------------PLNG----------HAHDSP-GWSRQLRVRDGDQFYLLDQEEVHPLLMNDHRPVSH-RHKLLRRTVSVPADSR---------PHPESEH--ARARRKSFATS----RQRSMETPPTAPTQPFRQPSFLSRRLKGSIKRAKSQPKLDRTGSFRHMILPRFRSADQ-------ERTRLMQSFKESH----------------SHESLLSPSSAAEALDLTLDEDAIIKPVHSSILGQEYCFEVTTASGTK-CFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKR----YYCELCLDDMLYARTTSKPR---TDTVFWGEHFEFNNLPAIRSLRLHLYKENDKKRRK-EKSTYLGLVSIPIPSVTGRQFVEQWYPLIQPS------VLAKGGGGG--------GKIINASLRLKSRFQSMNILPMELYKEFAEYVTNNYRTLCGVLEPLLSAKSKEE-----VACALVHILQSTGKAKDFLSDMAMCEVDRFMDREHLI--------------FRENTLATKAIEEFLKLIAHRYLKDTIGEGEFIRALYESEENCEVDPMRTPPSV-------LADHQANLRMCCELALCKIINSHCVFPRELKEVFASWRVRCAERGREDIADRLIS---SSLFLRFLCPAIMSPSLFNLTQEYPSERTSRTLTLIAKVVQSLASFSKFSGKEDYLGFMNEFLEMEWGSMQQFLYEISNLECVSNAGAFEGYIDLGRELSILHSLLWEVMAQLSK-------DAILKLGPLPRLLNDISVALRNPQLHRQASHQPPERHLSRPAFSRLATNDFQSLMMRDLNSSIDISRLPSP-TAGLSGSGVLSHPGMAAFSERDPRGNKDVFYVTR-PPLARSSPAYCTSSSDITEPDPKVLSVNKSVSMMDLQDS----RIN--SVSNLHSVNDLLNSSQGSLAGFGPLGGAPLRAGGRVSAGSGGSSMSGGLRLTTDSLSQQQQQAAAAMHVPLSFQNPLFHLASDGPQYHTPPHGPTAVPPPLLLAPEPENGHVGFGVP---TFA-HSGFSRSEDLSALRTQNSLVQPN----IVHSHSYSDDFTRHNQAD------YARRQLSLQVQENLQQQVLMGMTPQTATGTGTPASLATPPTTIHPVRQAS-MAPPPPQRAKPQPAHQLSVSSAVNSTPPKTRPQSGNLLQSPESSFGGRQLTRQQLSVKDSPAPGLPHQSSNASENPAPQSAANESTENTPTNQSAKNTQQSNQQHLLKPSGNKQGSKSPSTLN-PTSAASERTVAWVSNMPHLSADIESLRVDREEFKLKEHSKSMDESRLDRVREYEEEINSLKERLMMSHRKLEEYERRLHSQEQQTSKILLQYQSRLDDSERRLRQQQVEKDSQIKG---IIN-----------------------------------------------------RLMAVEDELR------GSGMPDLKTRIFTEQ----PIYGAHSGT-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C2K5-1", "uniprot_id": "RASL3_MOUSE", "id": "Q8C2K5-1", "name": "RAS protein activator like-3", "aln": "--------------------------------------------------------------------------------------------------------------------MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTG---------GSGEKAAGGFRWGRFAGWGRALSHQEPMVNSQPAPRSLFRRVLSAPPKESRSNRLRFSKTLWGRHKNVAPLEPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFTLLEGKLVMLG-EEEGPRQIRVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKRLKEKKRAKSELGAYTPRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWAGGSL-CFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATV--PGVRAELWLDGALLARTAPRAG---PGQLFWAERFHFEALPPARRLSLRLRSAGPAGATVGRVVLELDEVSIPRAPAAG---LERWFPVLGAPA--------------------------GAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELARCGGREALL--------------FRENTLATKAIDEYMKLVAQEYLQDTLG--QVVRCLCASTEDCEVDPSKCPTPE-------LPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEALGPRLVC---ASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQ-------KTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRISTQVQSS------------------------------------------------------------------------FFSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWASRRPDEERPQRRP-----------------------------RPVLRTQSVPARRPTHRRPSAGSKPRP------------------------------------------------------------------KGSLRMGPAPC---------------------------------------------------------------------------------GRAWTRASASLPRKPS----------------------------------------------------VPWQRQMDQPGDRYQTTG-----------------------------------THRPVG-------------------------------------------------KLAEIQCEVAIFREAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHR-------------------------------------------------------------LKSLEQRLTEMECSQDQLRDSLQSLQLLSKTPGSRSQPLPLKAPCVNGADLSMGT---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWW3-1", "uniprot_id": "D3ZWW3_RAT", "id": "D3ZWW3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MDPPLQNE-DSQTQ---PSPLTSYRWHTG---------GRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLG-EEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSR-CFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAA--PGVRAELWLDGALLARTAPRAG---PDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAG---LERWFPVLGAPA--------------------------GAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELERCGGREALL--------------FRENTLATKAIDEYMKLVAQEYLQETLG--QVVRSLCASTEDCEVDPSKCPTPE-------LPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVC---ASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQ-------KTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSS------------------------------------------------------------------------FSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRP-----------------------------RPVLRTQSVPARRPTHHRPAAGSKPRP------------------------------------------------------------------KGSLRTGPATS---------------------------------------------------------------------------------GRAWARTSTSLPRKPS----------------------------------------------------VPWQRQLDQPGDRYQTPG-----------------------------------THRPVG-------------------------------------------------KLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLG-------------------------------------------------------------LKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YV0-1", "uniprot_id": "RASL3_HUMAN", "id": "Q86YV0-1", "name": "RAS protein activator like-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MDPPSPSR-TSQTQPTATSPLTSYRWHTG---------GGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQPAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPP-EPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLE-----PRDGPPSALGSRESLATLSELDLGAERDVRIWPLHPSLLGEPHCFQVTWTGGSR-CFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAG---PGQLFWAERFHFEALPPARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAG---LERWFPLLGAPA--------------------------GAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELARCGGREALL--------------FRENTLATKAIDEYMKLVAQDYLQETLG--QVVRRLCASTEDCEVDPSKCPASE-------LPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLGPRLVC---ASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQ-------TTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSS------------------------------------------------------------------------LSAGEKPGFLAPRDLPKHTPLISKSQSLRSVRRSESWARPRPDEERPLRRP-----------------------------RPVQRTQSVPVRRPARRRQSAGPWPRP------------------------------------------------------------------KGSLSMGPAPR---------------------------------------------------------------------------------ARPWTRDSASLPRKPS----------------------------------------------------VPWQRQMDQPQDRNQALG-----------------------------------THRPVN-------------------------------------------------KLAELQCEVAALREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHS-------------------------------------------------------------LKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IR23-1", "uniprot_id": "Q8IR23_DROME", "id": "Q8IR23-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADLIHLGNIDVVIQKDKPGSPTGCS------------DDGNLAGLGGMTGLGGIMAPGGIDLGDLAQELDHDEFDGPHMLNGERPAIIAPPESEWYHGRLDRYS--AESRLRGSSK--------LGSYLVRESDRK----------------------PGSYVLSYYGRTGINHFRITAVCGDFYIGGRQFISLSDLVGY-YTSCSDLLKRERLAIPVAPPE-PVNDKKRVVAILPYTKMPETDELSFQKG--DIFFVHNDMGDGWLWVTAHRTG---EQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQR--------------------FRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHSLNHPVVNGIQPEFNQQY-----VVEKAAEKIYAT--LRECRDQIGLKKIKGIKHHGHLN--------------KKS-DKTTKWKQLYFALINDGSETQLCFYDNPKKTKPKGLIDLSCAYLYQCHDS-------LWERPYCFQIVERALPCLATVTYLCAP--SQESYVEWINSLKAQCDSQLSRAQKK---VSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEEEFVLD----DVPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTP---------MGEWGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHNDRVPLATALLR----------------------------------------VFRQEKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQR-------------------------------ILESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPD--------------------------------------ACPRNVRFICSCLQK---------------------------------------------------------------------------------------AVMAKWPTERLVRTR------------------------------------------------VVSGFIFLRLLCPALLNPRQFG--------------------------------LVSETPPMA----------------------------------------------ATRSLVMVAKCLQNLANLIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGMFVEQSTNLNS-----------------------------------------------------------------QDTGRELATLHHICVSHSQELHELSNILSIKKLVTVTDMLTKHKLKYREMIS-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "--------------------------------------------------------------------------------------------------------------------MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTG----ALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSN---SSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNK-KRLRLIGKIKITQEIINDTRYNKETRLPIMDVD---------------------NKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALS--AILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPY--------------LLDKNLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGK---------------------------------------------------------------GELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKITENNTEIFGDDLMN-------------------------------LLKSDDVGSRSRDLDNGANSGIKFN-------------------------------------------------------------SIIPKAEEEKHAMKELE-------------------------------------------------------------------------------------QESCLLYNRIN----------------------------------------------------HIRKRLSGYECASSTLFE----------------------------------DKKYSIS------------------------------------------------LSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSS-----------------------------------------------------------------NKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: * . . *: :: * .. : . . : . * : : :: : : . : :: : ** : :: : . . : . . . : . : : * : : .: * : . . . ** . . : * : : : : :: . . : :. . .. : * : . . . .: : : . : . . .. : . ", "identical_positions": 12, "similar_positions": 83, "identity": "0.7%" }, { "cls_id": "homologset.agr.SGD:S000001577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R431-1", "uniprot_id": "MGLL_RAT", "id": "Q8R431-1", "name": "Monoglyceride lipase", "aln": "-------------------------------------------MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAQMLKRLDMLVFAHDHVGHGQSEGER--MVVSDFQVFVR-DLLQHVNTVQKDYPEVPVFLLGHSMGGAISILAAAE--RPTHFSGMILISPLILANPESAS-TLKVLAAKLLNFVLPNISLGR-IDSSVLSRNKSEVDLYNSDPLICHAG-------VKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSPSQDKTLKMYEGAYH-VLHKELPEVTNSVLHEINTWVSHRIAVAGARCLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35678-1", "uniprot_id": "MGLL_MOUSE", "id": "O35678-1", "name": "Monoglyceride lipase", "aln": "-------------------------------------------MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAHMLKGLDMLVFAHDHVGHGQSEGER--MVVSDFQVFVR-DVLQHVDTIQKDYPDVPIFLLGHSMGGAISILVAAE--RPTYFSGMVLISPLVLANPESAS-TLKVLAAKLLNFVLPNMTLGR-IDSSVLSRNKSEVDLYNSDPLVCRAG-------LKVCFGIQLLNAVARVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSRSQDKTLKMYEGAYH-VLHRELPEVTNSVLHEVNSWVSHRIAAAGAGCPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99685-1", "uniprot_id": "MGLL_HUMAN", "id": "Q99685-1", "name": "Monoglyceride lipase", "aln": "-------------------------------------------MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGER--MVVSDFHVFVR-DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE--RPGHFAGMVLISPLVLANPESAT-TFKVLAAKVLNLVLPNLSLGP-IDSSVLSRNKTEVDIYNSDPLICRAG-------LKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH-VLHKELPEVTNSVFHEINMWVSQRTATAGTASPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT74-1", "uniprot_id": "A0AB32TT74_DANRE", "id": "A0AB32TT74-1", "name": "", "aln": "MNEISIMHMLATCLLVAAVSYWYSNELLTALHLFISDSTLSGDMPEPEGTRRSPQGVPYSDLPHIVNADGLHLFCRYWEPDGPPKALVYVAHGAGEHCGGYADIAHSLTQHGILVFAHDHVGHGQSEGER--MELKNFQIYVR-DSLQHIDIMKARYPKLAVFIVGHSMGGAISILTACE--RPQDFTGVVLIGPMVQMSAESAT-PFKVFMAKVLNRLAPKLTLGP-IDPKFVSRDPKQVEAYEKDELNYHGG-------LRVSFGMQMLDATSRIERELPDIRWPFYILHGDADKLCDIRGSRLLYNEAKSTDKKLKVYEEAYH-ALHHDLPETIESVLKEVSTWILERVPAPQTS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28321-1", "uniprot_id": "MGLL_YEAST", "id": "P28321-1", "name": "Monoglyceride lipase", "aln": "---------------------------------------------MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEAKP---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* : :: .*. ::* : . :. : : ** **: : * . *:.*: * * :. * .::::: : : . : : :.:*: ******.*.: *.: : ::* : .*:: ..: . : * :* . *.: :. :* . :: : .* : : * :: . . : *. :::*. * : * :*: : : . * ** **:* * * : : :. ::*::::. *: .: .. ", "identical_positions": 45, "similar_positions": 103, "identity": "12.47%" }, { "cls_id": "homologset.agr.SGD:S000001578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6J3-1", "uniprot_id": "YJU2_MOUSE", "id": "Q9D6J3-1", "name": "Splicing factor YJU2", "aln": "----MSERKVLNKYYPPDFDPSKIP--------KLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGK--KFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTD---------PENTDYTMEHGATRNFQAEKL---LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRMSQEQWQQQQEEEDERETAALLEEARHRRLLE-DSESEDEAPPSRPRAAARPNPTAILNEVPQTKR--------KAEA-------LCSKAQLAGLVVPKKVKTEANGASEQVGVPTAAGAPKSRKADNP-TPQTPG-------------TSSLSQLGAYGDSEDSDS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BW85-1", "uniprot_id": "YJU2_HUMAN", "id": "Q9BW85-1", "name": "Splicing factor YJU2", "aln": "----MSERKVLNKYYPPDFDPSKIP--------KLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGK--KFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTD---------PENTDYTMEHGATRNFQAEKL---LEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLE-DSDSEDEAAPSPLQPALRPNPTAILDEAPKPKR--------KVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANP-TPLTPG-------------ASSLSQLGAYLDSDDSNGSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WHR3-1", "uniprot_id": "YJU2_DANRE", "id": "A8WHR3-1", "name": "Splicing factor YJU2", "aln": "----MSERKVLNKYYPPDFDPSKIP--------KLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGK--KFNARKETVQNELYLGLPIFRFYIKCTRCLAEITFKTD---------PENTDYAMEHGATRNFQAEKL---IEEEEKKIQQEREDEELNNPMKVLENRTRDSKLEMEVLENLQELKELNQRQAQVDFEGMLGQYKELEQRQKQREQEEDEQETKEMLERALVKRLRDSDSEEEAENAKERSKKHIADKPTDILTTDTSTSSQGLSSAVAKKQSWDRSVGGLSVKGALGSLVVRKKPADSASKPSHAAPPPAAAAAGTQTGAVKPESSITSSSASSNIQPVSCQNGSSLGLLGAYSDSDDSSSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28320-1", "uniprot_id": "YJU2_YEAST", "id": "P28320-1", "name": "Splicing factor YJU2", "aln": "----MSERKAINKYYPPDYNPLEAEKLSRKMAKKLKTMNKSHASIRLMTPFSMRCLECNEYIPKSR--KFNGKKELLKEKYLDSIKIYRLTISCPRCANSIAFRTD---------PGNSDYVMEVGGVRNYVPQKP---NDDLNAKTAVESIDETLQR---LVREKEMEQNEKMGIKEQADDKMDLLEK-------------RLAKIQQEQEDDEELENLRKKNLEMSQRAEMINRSKHAQQEK------AVTTDDLDNLVDQVFDNHR--------------------------------QRTNKPGNNNDEKRTPLFNPTSTKGKIQKKS--------------------SVRTNPLGIVIKRGKSLK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M0R864-1", "uniprot_id": "M0R864_RAT", "id": "M0R864-1", "name": "SH2 domain-containing adapter protein D", "aln": "MAKWLRDYLNLGSRRPPPQPPTPDYTES-----DILRAYREQKDLDFEDPYEDSNGRPESEITESSDPKYNSPRHRLIKVEAVNLARAKTLLGSLGEEPEADTEYSDPFDAQPQPPAPNNGYMEPYDARNISSEQPSRAVQLYDTPYEEQDMKPEDGGSSGQSRRPLEDERPADEYDQPWEWKKDHISRAFAVQFHGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRVEAENLLSLCKEGSYLVRLSETRAQDCILSLR-----------SNQGSMHLKFAKTRENQVVLGQHSGPFPSVPELVLHYSARPLPVQGIEHLALLYPVTSS-------------QSSQGPCTLAARPEKGQGDP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. ** * .: : : : *:. . * :. *:*. :. : : .: : : . . . . * .: ** .** .:: : : : . .. :.. : : : .: . . . : . ** . . : :: . . . . . .. ", "identical_positions": 14, "similar_positions": 66, "identity": "3.76%" }, { "cls_id": "homologset.agr.SGD:S000001582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5K5-1", "uniprot_id": "UTP11_RAT", "id": "Q8R5K5-1", "name": "Probable U3 small nucleolar RNA-associated protein 11", "aln": "MAAAFRKAVKSRQREYRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDG-----VHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNRHVFFFDTKKEVEQFDVAAHLQTAPELVDRVFNRPRIETLQK--EKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDK--TQKVKVKKETVNSPAIYKFQSRRKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3A2-1", "uniprot_id": "UTP11_HUMAN", "id": "Q9Y3A2-1", "name": "Probable U3 small nucleolar RNA-associated protein 11", "aln": "MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDG-----VHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQK--EKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDK--TQKVKVKKETVNSPAIYKFQSRRKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZJ1-1", "uniprot_id": "UTP11_MOUSE", "id": "Q9CZJ1-1", "name": "Probable U3 small nucleolar RNA-associated protein 11", "aln": "MSAAFRKAAKTRQREHRERSQPGFRKRLGLLEKKKDYKLRANDYHKKQDFLRALRKKALEKNPDEFYYKMTRAKLQDG-----VHIFKENKEEVTAEQLKLMRTQDIKYIEMKRVAEAKKIERLKSELHLLDFQGKQQKKHVFFFDTKKEVERFDVATHLQTAPELVDRVYNRPRIETLQK--ERVKGATPQTGLKRIAKERQKQYDCLTQRIEREKQLFVVAQKIQTRKDLMDK--TQKVKVKKETVNSPAIYRFQTRRKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W3C0-1", "uniprot_id": "UTP11_DROME", "id": "Q9W3C0-1", "name": "Probable U3 small nucleolar RNA-associated protein 11", "aln": "-MSSWKNASKSNQKVHRERHQPESRQHLGFLEKKKDYKKRAIDAQKKQKTLKLLYRRAQNKNPDEFYHHMINSKLSND-----EHHEKDTKDEHTPEQLALMQTQDLKYVVMKRTMERKKIERLKASLVDVDAIKGAANKRIKFDE--DGYMELDMGEWLLKHDDEEE--------EEEKK--KKSK-TTEPNPIK------QQRINELKKREQRERELGIVQQKIQLKNTLKQPRLLKPRKIKPGTKDSAPVYKFRYERKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34247-1", "uniprot_id": "UTP11_YEAST", "id": "P34247-1", "name": "U3 small nucleolar RNA-associated protein 11", "aln": "---MAKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRKQSTLKVLREKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKTQDSNYVRTLRQIELKKLEKGAKQLMFKSS-----GNHTIFVDSREKMNEFTPEKFFNTTSEMVNRSENRLTKDQLAQDISNNRNASSIMPKESLDKKKLKKFKQVKQHLQRETQLKQVQQRMDAQRELLKK----GSKKKIVDSSGKISFKWKKQRKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .:: :*** * *.: *:***:*** ** * ::**. *: * .:* ::****:*: * * . : .: .:. : :*: *::*** :*: * * **:*: .* . .: * : . .: : . : : : : .. : .: : :: . :.:: :** :* : *::: :. * . * * .. :::: .**:", "identical_positions": 49, "similar_positions": 81, "identity": "18.7%" }, { "cls_id": "homologset.agr.SGD:S000001583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8V0-1", "uniprot_id": "SPP_MOUSE", "id": "Q9D8V0-1", "name": "Signal peptide peptidase", "aln": "------------------------------------------MDSAVSDPHNGSAE-AGTPANGTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKSSS-DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ANFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSVVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMF--SYEESNPKDP-AAETESKEESTEASASKRLE-KKEK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP98-1", "uniprot_id": "D3ZP98_RAT", "id": "D3ZP98-1", "name": "", "aln": "------------------------------------------MDSALSDPHNGSSE-AGTPANGTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKSSS-DMPETITSRDAARFPIIASCTLLGLYLFFKLFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ANFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSVVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALVKGEVAEMF--SYEESNPKDP-AAVTESKEESTEASASKRLE-KKEK---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TCT9-1", "uniprot_id": "SPP_HUMAN", "id": "Q8TCT9-1", "name": "Signal peptide peptidase", "aln": "------------------------------------------MDSALSDPHNGSAE-AGGPTNSTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKNAS-DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ASFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSIVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMF--SYEESNPKDP-AAVTESKE-GTEASASKGLE-KKEK---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPQ7-1", "uniprot_id": "SPP_DROME", "id": "Q9VPQ7-1", "name": "Signal peptide peptidase", "aln": "--------------------------------------MAEEVIGTVKEVLKGIIENVNAPKNESAPGEKKPSTPEGMAVAYSSLVVMAMLPIIFGSIRSVK------------------------------------LHKLKKSTGEKADTMTKKDAMYFPLIASAALFGLYLFFKIFQKVHINYLLTGYFFVLGVIALAH---LLSPVINSLMP---------AAVPKVPFHILFTKGEG---------------------------------------------------KHKEDIVNYKFSTHDIVCLVISSAIGVWYLLK-KHWIANNLFGLAFAINGVEMLHLNNFVTGVILLSGLFFYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLIENGLNASNFAMLGLGDIVIPGIFIALLLRFDDSKKRKTR--------------IYFYSTLIAYFLGLLATIFVMHVFKHAQPALLYLVPACMGTPLLVALIRGELKVLF--AYEDHPEEKPEKKEKKEKDEGVSSSGSKKKESKKGK---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34248-1", "uniprot_id": "SPP_YEAST", "id": "P34248-1", "name": "Intramembrane protease YPF1", "aln": "MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQINAIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSISSIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAIILPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNLSHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKDHWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLPVKFNTAQNNFN-FSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKYFITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQYDTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEEDLSDSSEEELSEEDLLDDESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.: : . : ...:.. *.:*:::* :.:*:: *: : *. : : : .:.* :*: :..:*:.**:.:* : :: ::. * : :: :. * .:*.:: . . ::: ::... : *.:* * :.: :*.: :* *:: * :.*: .* ..: ::: .: *:*:*. :* ::* .**:**: :****:******..:: *:** :* .: : . *::*****:.:**:***: ::* : : ** ::: :*. .* ::. : :*: *******:**: : .:*** . :. :: *: ... :.*: . * * : ", "identical_positions": 80, "similar_positions": 157, "identity": "13.61%" }, { "cls_id": "homologset.agr.SGD:S000001584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJI5-1", "uniprot_id": "BRSK1_MOUSE", "id": "Q5RJI5-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGR------------------RVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGSGGSPVPT------------------RRALEMAQHSQ-----------------------RSRSVSGASTGLSSSPLSSPR----------SPVFSFS-------------------PEPGAGDEARGGG-SPTSKTQTLPSR----GPRGGGAGEQPPPPSARSTPLPG--------------------------------------------------------------------------------------PPGSPRSS-GGTPLHSPLHTPRASPTGTPGT---------------------------------------------------------------------------TPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRR--------KMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD-----KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG--GPSVFQKPVRFQVDISSSEGPEPSPR-----RDGSSGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------------------SVQ----ALADE-----KNGAQTRPAGTPPR--SLQPPPGRSDPDLSSS----------------PRRGPPKDK-KLLATNGTPLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2DD29-1", "uniprot_id": "BRSK1_RAT", "id": "B2DD29-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGR------------------RVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGSGGSPVPT------------------RRALEMAQHSQ-----------------------RSRSVSGASTGLSSSPLSSPR----------SPVFSFS-------------------PEPGVGDEARGGG-SPTSKTQTLPSR----GPRGGGAGEQPPPPSARSTPLPG--------------------------------------------------------------------------------------PPGSPRSS-GGTPLHSPLHTPRASPTGTPGT---------------------------------------------------------------------------TPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRR--------KMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD-----KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG--GPSVFQKPVRFQVDISSSEGPEPSPR-----RDGSSGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------------------SVQ----ALADE-----KNGAQTRPAGTPPR--SLQPPPGRPDPDLSSS----------------PRRGPSKDK-KLLATNGTPLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDC3-1", "uniprot_id": "BRSK1_HUMAN", "id": "Q8TDC3-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGAKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGR------------------RVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPT------------------RRALEMAQHSQ-----------------------RSRSVSGASTGLSSSPLSSPR----------SPVFSFS-------------------PEPGAGDEARGGG-SPTSKTQTLPSR----GPRGGGAGEQPPPPSARSTPLPG--------------------------------------------------------------------------------------PPGSPRSS-GGTPLHSPLHTPRASPTGTPGT---------------------------------------------------------------------------TPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRR--------KMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD-----KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG--GPSVFQKPVRFQVDISSSEGPEPSPR-----RDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------------------SVQ----ALADE-----KNGAQTRPAGAPPR--SLQPPPGRPDPELSSS----------------PRRGPPKDK-KLLATNGTPLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GWU6-1", "uniprot_id": "A0AC58GWU6_DANRE", "id": "A0AC58GWU6-1", "name": "", "aln": "--------------------------------------------------MSKELSV--------------TQAAQYVGPYRLEKTLGKGQTGLVKLGIHCITSQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENNKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILFALLVGALPFDHDNLRQLLEKVKSGVFHMPHFIPPDCQALLRGMIEVNPEKRLTLEAIQKHAWYQAGRNEP--CPEQPPPR------------------RVSMGRIMSLTELDPDVLDSMYSLGCFRDRVKLAQDLQCEEDNQEKMIYYLLLDRKERYPSYEDEDLPPR------NDVDPPRKRVDSPMLTRHGRCRPERKSLEVLSVTEQG---SPTPP------------------RRALDTSTHSQ-----------------------RSRSVSGASTGLSSSPLSSPR----------SPVFTFSEPEVVAAT------------KATSGSTNSRPNRSHEPKTQTLPSKNAPERPQLQSMKSLPLPSSSSRSPSPSPLLSPIPRFLFFPSPSAVLKSVT-------------------------------------------------KSLYP----MSQVTPQGSPLPTPLGTPVHHPHPPTATPPSSSSSSSSSRAEGGG----------------------------------------------------------VGVGSLSLTPPSSPGGGGGMAASSSAHWRTRLNSLKNNLLGSPRFHRR--------KLQVPTSEDMSSLTPESSPELAKRSWFGNFISLEKEEQIFVVIRD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKTSG--GPSVFQKPVKFQVDISFSEGERERERERERDRDGQKDFGIYSVTFSLISGPSRRFRRVVETIQAQLLSA-------------------------HDQT----------------------------MVQTFSACLCSS-----PDEKNSRPPRTPTRQNSRRSEGGGDRCEWVERGEGG---------VLLQRRGSGKERTRLLSSSGTQSQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AY36-1", "uniprot_id": "A0A8M3AY36_DANRE", "id": "A0A8M3AY36-1", "name": "", "aln": "-------------------------------------------------MSSKELSG--------------SQAAQYVGPYRLEKTLGKGQTGLVKLGVHCITTQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLYDVYENNKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILFALLVGALPFDHDNLRQLLEKVKSGVFHMPHFIPPDCQALLRGMIEVNAEKRLTLEEIQKHPWYQGGRNEP--CPEQPPPR------------------RVCVKRILSLTDLDPDVLESMHSLGCFRDRVKLTRDLQCEEENQEKLIYYLLLDRKERYPSYEDEHLPPR------NDVDPPRKRVDSPMLTRHGRCRPERKSLEVLSVTEQG---SPTPP------------------RRALDTSAHSQ-----------------------RSRSVSGASTGLSSSPLSSPR----------SPVFTFSQTEVTSASATQSKD-----PKAGSSTTPRASQRAPEQKTQTLPTKAASDRPHLQSMKSLPLQTPPSPSPSPSPLLSPIPRF-FFPAP-SVLKSVT-------------------------------------------------KTIYPNSAHVSQVTPQGSPLPTPLGTPVHHPQHPPPTPPSSSSSSSSSRAEGGGG-------------------------------------------------------GGVGGGSLSLTPPSSPGGSGGMAASSSAHWRTRLNSFKNNLLGSPRFHRR--------RLQVPTSEDMSSLTPESSPELAKKSWFGNFISLEREEQIFVVIRD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKSSG--GPSVFQKPVKFQVDIAFSEGERERERDKDREREGRRETGIYSVTFTLLSGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------------------SVQ----ALADE-----KNGLSSRPPSTPTRQNSRRSEGGGDRGERAERADRGEGSSIGGSVSVLQRKGSGKDKTRLLSSNGTQSQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IWQ3-1", "uniprot_id": "BRSK2_HUMAN", "id": "Q8IWQ3-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-----------------------------------------------MTSTGKDGG---------------AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPE--PEQPIPR------------------KVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPR------NEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGG---SPVPA------------------RRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNP---------------------------------------------------------------------------TPPSSP--SVGGVP-----WRARLNSIKNSFLGSPRFHRR--------KLQVPTPEEMSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG--GPAVFQKPVKFQVDITYTEGG-----------EAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLST-------------------------HDPPAAQHLSDTTNCMEMMTGRLSKCGSPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPG------------GDAEYPTG--KDTAKMGPPTARREQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69Z98-1", "uniprot_id": "BRSK2_MOUSE", "id": "Q69Z98-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-----------------------------------------------MTSTGKDGGG--------------AQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPE--PEQPIPR------------------KVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSHEDEDLPPR------NEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGG---SPVPA------------------RRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNP---------------------------------------------------------------------------TPPSSP--SVGGVP-----WRTRLNSIKNSFLGSPRFHRR--------KLQVPTPEEMSNLTPESSPELAKKSWFGNFINLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG--GPAVFQKPVKFQVDITYTEGG-----------EAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLST-------------------------HDQPSAQHLSDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG--------------GDTEYPMG--KDMAKMGPPAARREQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZML2-1", "uniprot_id": "BRSK2_RAT", "id": "D3ZML2-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-----------------------------------------------MTSTGKDGGG--------------AQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPE--PEQPIPR------------------KVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSHEDEDLPPR------NEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGG---SPVPA------------------RRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNP---------------------------------------------------------------------------TPPSSP--SVGGVP-----WRTRLNSIKNSFLGSPRFHRR--------KLQVPTPEEMSNLTPESSPELGHLQLFGNPVSKVRSVAMELVILV-----QTLAYTSFRLLGTFLPVRYLRHSVLSRPPERARLVLRG--APCTHMGPVWNMVGMAYTQNP-----------PIMGETGVYGSQWVMSSAPSKHYTSLGLSVPSPSCSL-------------------------SPSLFPFCAPDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG--------------GDTEYPMG--KDMAKMGPPAARREQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B1F0-1", "uniprot_id": "A0A8M3B1F0_DANRE", "id": "A0A8M3B1F0-1", "name": "", "aln": "-----------------------------------------------MSSSGKDNSS--------------QQHANYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRNLLEKVKLGVFHMPHFIPPDCQNLLRGMIEVDATKRLTLEQIQKHTWYIGGKNEPE--PEQPVPR------------------KVAIRTLPSTEDIDPDVLESMHSLGCFRDKNKLMKDLLSDDDNQEKMIYFLLLDRKERYPSHEDQNLPPR------NEIDPPRKRVDSPLLTRHNKRRPERKSMEVLSVTEGG---SPVPV------------------RRAIDMAQHGQSKSVFSKSLDISDANPILQSKEERSRSISGASSGLSTSPLSSPRPMRRFAVPPQSSDLTYSPNHSPTHAPVARLNGTGPHSPKIFLPKTAADQLN--NKTQTLPAKPKVADKPLQATRSNPLPNSTP-VPPVAKSEPSTPCQPLPPQIPGSPKIRR--PPLTVPPKLSVPLS---PLS---------------PIRLHHLHPLAGTDHNGKSIPTIQVTPHPSPRGSPLPTPKGTPVHTPKESPAGTPSP---------------------------------------------------------------------------TPPPSP--SIGGMP-----WRTRLNSIKNSFLGSPRFHRR--------KLQVPTQEEMSSLTPESSPELAKKSWFGNFINLEKEEQIFVVIRD-----KPLSSIKADIVHAFLSIPSLSHSVVSQTSFRAEYKSTA--GPTVFQKPVKFQVDITYTESM-----------AATKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------GVQQLSGSPLSNFFDVIKQLFSDE-----KNGQVSHPPGTP--KHANSKRHE---PEPN---------------DSKCPSG--QDKAKMAPSVGTQEQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YYI9-1", "uniprot_id": "A0A8M6YYI9_DANRE", "id": "A0A8M6YYI9-1", "name": "", "aln": "-----------------------------------------------MSLSGKENST--------------TPHANYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRNLLEKVKLGVFHMPHFIPPECQNLLRGMIEVDSGKRLTLELIQKHMWYIGGKNEPE--PEQPVPR------------------KVAIRSVPSSEDIDPDVLESMHSLGCFRDKNKLMKDLLSDDENQEKMIYFLLLDRKERYPSQEDQNLPPR------NDIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGG---SPVPA------------------RRAIDMTQHGQSKSTFSKSLDISDAKHKAKSKEERSRSISGASSGLSTSPLSSPRPVRKFCVPPQSSELLLSPSSSIIDSLKPNSDQNMAKTSNSLTPNSISESLLPYPKTQTLPAKPK--DKPLQSARSNPLPESEPEHISTAKSEPSTPCQPQAPCIPGSPLVRRATPASIIPPQLSVPFRPAVPLS---------------PIRLHHFHPVPGSDHTTKSIPTIQVTPHPSPRSSPIPTPKGTPIHTPKNSPAGTPTP---------------------------------------------------------------------------TPPPSP--SIGGMP-----WKTRLNSFKNSFLGSPRFHRR--------KLQVPTQEEMSSLTPESSPELAKKSWFGNFINLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKSTA--GPTVFQKPVKFQVDITYTEST-----------AANKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLST-------------------------HDQP----------------GVQQLSGSPLSNFFDVIKQLFSDE-----KNSQVPVPPGTPNRHPPNARRHD---PQPN---------------DSKCPPGNPRDNAKLVASAETQEQL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUV4-1", "uniprot_id": "Q9VUV4_DROME", "id": "Q9VUV4-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------MQKENNVT-------------AENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINRE------------------------------------KLSESVLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAG-GKGELELELPMME------------------VVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRIN--GTNAPSYG-----QISEGS---PLTPR------------------RQAFNFRSYSSTRN-------------------HQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAG----------TRHSTYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGS---------------------------------------------------TSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSP--------------------------------------------------------------------------GMPGSPCNTPGGQL-----WKTRLTNIKNSFLGSPRFHRR--------KMQVSADEVH--LTPESSPELTKRSWFGNLITTEKDETFTILVKG-----KPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGN-GPVMFQRHVKFQVDISAICKQ------------GDIADMLFALTFTLLSGNIRRFRRICEHIQSQVCSKR-----------------------FPGPSSPPTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKSGNGRRASTTNNNNANPVDIPGSPIAVRSNS------------ETAEHERNRELQSERQATTMSGSAIA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34244-1", "uniprot_id": "HSL1_YEAST", "id": "P34244-1", "name": "Probable serine/threonine-protein kinase HSL1", "aln": "MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKS-ATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : ***::* ******.:* *:*. : : .*:**: :: : *:: :****.*:***.*.:*: * :*:**:. ***:**:*.*********.**:*. :** ::*:**:..:.:***..**************::*. *:*******:*: ..:*:*********.**:: *. *.* :*:****::*:***.* ***:.**:::** **: * :::* :..:.: *: :: ::. :*:: * :* . : : :* .:* :: * .: : .* . . **::* ***: *.* . .. : . :: ** . : . . . .: . . . : :. .. * :.: : . * . . * . . . :.. :.:* . :*::. : .: * .* .:.:: . : . . :: :.: :: : :.. * : : . : . : . * . : . : .. . . . . : . ", "identical_positions": 144, "similar_positions": 198, "identity": "9.48%" }, { "cls_id": "homologset.agr.SGD:S000001586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A8L3-1", "uniprot_id": "A0A8I6A8L3_RAT", "id": "A0A8I6A8L3-1", "name": "Aspartyl aminopeptidase", "aln": "--------------------MNPPEAEVAMNGRARKEA----------IQATARELIKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWDILPEN---KYFLTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRR-SQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRFVH-IERPILRIPHLAIHLQRNVNENFGPNTEMHLVPILATAVQEELEKGTPEPGPLSATDERHHSVLMSLLCTHLGLSPDNIMEMELCLADTQPATLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLAREPHVRMVTLYDNEEVGSESAQGAQS-LLTELILRRISASPQRLTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESLIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2W0-1", "uniprot_id": "DNPEP_MOUSE", "id": "Q9Z2W0-1", "name": "Aspartyl aminopeptidase", "aln": "---------------------------MAMNGRARKEA----------IQATARELLKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWDIVPEN---KYFLTRNSSSIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRR-SQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRLVH-IERPILRIPHLAIHLQRNINENFGPNTEIHLVPILATAVQEELEKGTPEPGPLGATDERHHSVLMSLLCTHLGLSPDSIMEMELCLADTQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLARDPHVRMVTLYDNEEVGSESAQGAQS-LLTELILRRISASPQRLTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESMIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULA0-1", "uniprot_id": "DNPEP_HUMAN", "id": "Q9ULA0-1", "name": "Aspartyl aminopeptidase", "aln": "---------------MSGHSPTRGAMQVAMNGKARKEA----------VQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELKETEKWNIKPES---KYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRSRR-SQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVH-VERPILRIPHLAIHLQRNINENFGPNTEMHLVPILATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCAHLGLSPKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYDNEEVGSESAQGAQS-LLTELVLRRISASCQHPTAFEEAIPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNLLVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14904-1", "uniprot_id": "AMPL_YEAST", "id": "P14904-1", "name": "Vacuolar aminopeptidase 1", "aln": "MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDE-KKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESD-LFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : :** : *:*::.*: :.*:.:*.*: . * : .* *.*.. *: . *:: **.:.: ** :* :: . :*..:**:*.*: :::* * : : *: ::.* .*** : . *:**** :.**:: * :..::. :*. *: *** ** *: : : *. : : * :.*. :* * * : .. :* *: :. *:. ..:::*:* * *.* ..:** ..*:******: ..*.*: *** . . : : . ********:** : ***:. ** .:: * ** :: . :. . .:*:::***: * :**: : : :** *: : * .:.::.: : *::.*. :::.*:* : :* : ::*:: .* **** ***: * *.:*** .**:***** : :..* :.:*:***: : *: :: ", "identical_positions": 137, "similar_positions": 179, "identity": "26.55%" }, { "cls_id": "homologset.agr.SGD:S000001587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KMC4-1", "uniprot_id": "GFPT2_RAT", "id": "Q4KMC4-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "aln": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNN---HEVKERHIHLVKKKGKVKALDEELYKQDS-MDLKVEFETHFGIAHTRWATHGVPNVVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDN--RETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCTIEN-----------------VKNICKTRLKRLDSSTCLHAVGD--------------------KAVEFFFASDASAIIEHTNRVIFLEDDDIAAVA-DGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQTRRQEIIRGLRSLPELIKEVLSLDEKIHDL-ALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDD----TESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Z9-1", "uniprot_id": "GFPT2_MOUSE", "id": "Q9Z2Z9-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "aln": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNN---HEVKERHIHLVKKRGKVKALDEELYKQDS-MDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDN--RETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYPTCNIEN-----------------VKNICKTRMKRLDSSTCLHAVGD--------------------KAVEFFFASDASAIIEHTNRVIFLEDDDIAAVA-DGKLSIHRVKRSATDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLDEKIHDL-ALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDD----TESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94808-1", "uniprot_id": "GFPT2_HUMAN", "id": "O94808-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "aln": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNN---HEVKERHIQLVKKRGKVKALDEELYKQDS-MDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDN--RETEDITFSTLVERVIQQLEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLEN-----------------VKNICKTRMKRLDSSACLHAVGD--------------------KAVEFFFASDASAIIEHTNRVIFLEDDDIAAVA-DGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDL-ALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDD----TESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47856-1", "uniprot_id": "GFPT1_MOUSE", "id": "P47856-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQD-MDLDIEFDVHLGIAHTRWATHGEPNPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDN--WESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSTW-----WGSQAERGKDKKGSCGLSRVDSTTCLFPVEE--------------------KAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKL-ATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKED----TETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82808-1", "uniprot_id": "GFPT1_RAT", "id": "P82808-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQD-MDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDN--WESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTG---------------------KDKKGSCGLSRVDSTTCLFPVEE--------------------KAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTARDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGMATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKL-ATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKED----TETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06210-1", "uniprot_id": "GFPT1_HUMAN", "id": "Q06210-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQD-MDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDN--RESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFT---RWGSQGERGKDKKGSCNLSRVDSTTCLFPVEE--------------------KAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKL-ATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKED----TETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAW3-1", "uniprot_id": "Q9VAW3_DROME", "id": "Q9VAW3-1", "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "aln": "MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSG----EAQSIMLVKRTGKVKVLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVVHNGIITNYKDVKTLLEKRGYVFESDTDTEVIAKLVHHLWQQ--HPG--YTFGELVEQAIQQLEGAFAIAFKSKHFPGECVASRRGSPLLVGIKAKTKLATDHIPILYAKAHR--------PHGQPQ-------QQAYQLLPPGDCNAEFQPLER--------------------KEVEYFFASDASAVIEHTNRVIYLEDDDVAAVKSDGTLSIHRLNKSSDDPHAREIITLKMEIQQIMKGNYDYFMLKEIFEQPESVVNTMRGRMRFDTQTVVLGGIKEYIPEIKRCRRLMLIACGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGVTNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEIIDGLSQLDEHIRTVLKLNSQVQQL-AKELYEHKSLLIMGRGFNFATCLEGALKVKELTYMHSEGILAGELKHGPLALVDKEMPVLMIVLRDPVYTKCMNALQQVTSRKGRPILICEEGD----NETMSFSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGCDVDCPRNLAKSVTVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLC7-1", "uniprot_id": "Q7PLC7_DROME", "id": "Q7PLC7-1", "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "aln": "MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPDN-------KNIVMVKRTGKVKVLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVVHNGIITNYNDVKTFLSKRGYEFESDTDTEVFAKLVHHLWKT--HPT--YSFRELVEQAILQVEGAFAIAVKSKYFPGECVASRRSSPLLVGIKTKTRLATDHIPILYGKDDKKLCTDQDADSGKPQDIRPHGQSRELPVLPRSESTSEFMPLEE--------------------KEVEYFFASDASAVIEHTNRVIYLEDDDVAAVR-DGTLSIHRLKKSLDDPHAREITTLKMEIQQIMKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIKDYIPEIKRCRRLMLIGCGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEILQALSKLADQIRDVLQLDSKVKEL-AKDLYQHKSLLIMGRGYNFATCLEGALKVKELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCPIIICEEGD----EETKAFSSRHLEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLAKSVTVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14742-1", "uniprot_id": "GFA1_YEAST", "id": "P14742-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing]", "aln": "MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDGDE-------ADSTFIYKQIGKVSALKEEITKQNP--NRDVTFVSHCGIAHTRWATHGRPEQVNCHPQRSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGHDLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDVEFPEENAGQPEIP----LKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAFLSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIY-DGELHIHRSRREVGASMTRSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLPVVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVFVSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATELKDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAFGTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQGLINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.* ** . ::* *::: *: **:*********:*:.:*. : : *: ***..*.: : : : . . * *********** * *.**:*** : *:*:*******:.:::.:* .:** ***:**** :*** :::. * *.: .: ::**::.: ** ::*.: :.:*:.****:*:::: :* .: : : : : . .: : .: . **::.:***:::::**::*::*****:* : ** * *** .: * : **:**: ***** :. ** ***:***:*..******: :: : ***:* : ::*.***::*.******: :*** ::***:::** **********: *:******.*:*********::.*.** :**** **:.*:*****.* :.**********************:::****.* :.:**:* ** **: .* : *: **.:: .::.* * :* ::*:*::***:::*:.******:**::******::******* ***:*. :*:: . :* : * .:::**.:*:* *:::*.: * :: : :::*::******::.:**:**::: :** :* *** ***********", "identical_positions": 305, "similar_positions": 217, "identity": "41.72%" }, { "cls_id": "homologset.agr.SGD:S000001589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00507-1", "uniprot_id": "AATM_RAT", "id": "P00507-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSGRVLSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAGKNLDKEYLPIGGLADFCKASAELALGENSEVL-----KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEMAAVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTVVCKDAEE-------------AKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05202-1", "uniprot_id": "AATM_MOUSE", "id": "P05202-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSSRILSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVL-----KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTVVCKDAEE-------------AKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00505-1", "uniprot_id": "AATM_HUMAN", "id": "P00505-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVL-----KSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTMVCKDADE-------------AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJR0-1", "uniprot_id": "A0A8I6GJR0_RAT", "id": "A0A8I6GJR0-1", "name": "Aspartate aminotransferase", "aln": "-MALLHSR-----MATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQR---PRLLEKIWTKNAYPSG----------------------------DWLVFVRLLQ-----RSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQS---------VLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGIN------VCLCQSYAKNMGLYGERVGSFTVVCKDEEE-------------AKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMF------------------FYMIKDGRISVAGVTSGNVCYLTHAIHQVTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SYK7-1", "uniprot_id": "AATM_DANRE", "id": "Q7SYK7-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALFKSSKILSSVGSQTP--VLAVLQLRASSWWTEVQMGPPDPILGVTEAFKRDTNPKKMNLGVGAYRDDQGKPFVLSSVRKAE---AQIAAKKLDKEYLPIGGLADFSKACVQLALGPDNEVL-----KSGRSITVQTISGTGSLRIGANFVSRFHNASRDVYLPKPSWGNHTPVFRDAGMQLKAYTYYEPKTCGFNLKGALDDISKIPEKS---------VILLHACAHNPTGVDPRPEQWKEMAALIKKRNLLVFFDMAYQGFASGDIDRDAWAVRYFIEQGHN------ILLSQSFAKNMGLYGERVGGFTVVCKDAEE-------------AKRVESQLKILIRPIYSNPPMNGARIAATILNTPELYKEWLQEVKGMADRIIRMREMLVSNLKKEGSTHNWQHVTDQIGMFCFTGLKPEQVERLINEFSIYMTKDGRISVAGVTSANVEYLAHAIHAVTK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPY3-1", "uniprot_id": "Q8IPY3_DROME", "id": "Q8IPY3-1", "name": "Aspartate aminotransferase", "aln": "MSRTIIMTLKDIVHVWSNDPGERMCRANRVSTWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAE---KRVVSRSLDKEYATIIGIPEFYNKAIELALGKGSKRL-----AAKHNVTAQSISGTGALRIGAAFLAKFWQGNREIYIPSPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKS---------IVLLHACAHNPTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHD------FCLAQSFAKNMGLYGERAGAFTVLCSDEEE-------------AARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIIDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNVEYLAESIHKVTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01802-1", "uniprot_id": "AATM_YEAST", "id": "Q01802-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "--------------MLRTRLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNVNKIDLTVGIYKDGWGKVTTFPSVAKAQKLIESHLELNKNLSYLPITGSKEFQENVMKFLFKESCPQFGPFYLAHDRISFVQTLSGTGALAVAAKFLALFIS--RDIWIPDPSWANHKNIFQNNGFEN-IYRYSYYKDGQIDIDGWIEQLKTFAYNNQQENNKNPPCIILHACCHNPTGLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAYLLRLCLNVNKYPNWSNGIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNIDSQLKKIVRGMYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRLG----WPDLVNFAQQHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSKMDKLA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* .*** :**::* **: .* :*::* . *:*. : :.*: . . . . .: :. . * : . : : *. . . . . ::: * ::::. :. :. ::****.*** *:** *:*.:: : : .: :.******: :*: :** :: . . *.**:**********.*.:::: : .: **:* ::* :**.** *:*:. :*. .* :*:::*. *.:*: * : ..* : :..:* *** .*: ***:*::**.. ** ** .::. *:* ", "identical_positions": 88, "similar_positions": 122, "identity": "18.64%" }, { "cls_id": "homologset.agr.SGD:S000001593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0L7-1", "uniprot_id": "KTI12_RAT", "id": "Q5I0L7-1", "name": "Protein KTI12 homolog", "aln": "MPLVVVCGLPSSGKSRRTEELRRALTG-EGRSVYVVD-----DASVLGAQDSTVYGDSAGEKALRAALRAAVERRLSRQDVVILDSMNYIKGFRYELYCLARAVRTPLCLVYCIRPGWPSRGLPVPGACESSDPAVSVSWRPRADYGEKTQAVG--AV-EQRAISPLANGGVPTAVPKELDPKDILPSNPPAVMTPESEKSAEPAPCAFP-PELLESLALRFEAPDSRNRWDRPLFTVVGLEEPLP--LAEIRSALFENRAPP---------------PHQSTQSQPLASGSFLHQLDQATSQVLTAVMEAQK-------SAVPGDLLTLPGTTEH---------LRFTRPLTLAELSRLRRQFISYT--KMHPNNENLPQLANMFLQYLNQSLH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1R2-1", "uniprot_id": "KTI12_MOUSE", "id": "Q9D1R2-1", "name": "Protein KTI12 homolog", "aln": "MPLVVVCGLPSSGKSQRTEELRRALAS-EGRAVYVVD-----DASVLGAQDPTVYGDSAGEKALRAALRAAVERRLSRQDVVILDSVNYIKGFRYELYCLARAARTPLCLLYCVRPNWPSRELREASASENRDLAVSVSWRPRAETGGKSQAAG--AVEEQRATSPVANGGVLAAVSKELDPEEILPSNPSAVMTPGSEKSAEPASCAFP-PEVLESLALRFESPDSRNRWDRPLFTVVGLEEPLP--LAEIRSALFENRAPP---------------PHQSTQSQPLASGSFLHQLDQATSQVLTAVMEAQK-------SAVPGDFLKLPGTTEP---------LRFTRPLTLAELSRLRRQFISYT--KMHPNNENLPQLANMFLQYLNQSLH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EK9-1", "uniprot_id": "KTI12_HUMAN", "id": "Q96EK9-1", "name": "Protein KTI12 homolog", "aln": "MPLVVFCGLPYSGKSRRAEELRVALAA-EGRAVYVVD-----DAAVLGAEDPAVYGDSAREKALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVRPGGPIAGPQVAGANENPGRNVSVSWRPRAEEDGRAQAAGSSVLRELHTADSVVNGSAQADVPKELEREESGAAESPALVTPDSEKSAKHGSGAFYSPELLEALTLRFEAPDSRNRWDRPLFTLVGLEEPLP--LAGIRSALFENRAPP---------------PHQSTQSQPLASGSFLHQLDQVTSQVLAGLMEAQK-------SAVPGDLLTLPGTTEH---------LRFTRPLTMAELSRLRRQFISYT--KMHPNNENLPQLANMFLQYLSQSLH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P457-1", "uniprot_id": "KTI12_DANRE", "id": "Q0P457-1", "name": "Protein KTI12 homolog", "aln": "MPLILMCGYPCSGKTRRAQELRDYFTQNTGRKVHIVG-----DED-QGIDKNSVYADSQKEKNLRGALRAEVERKVNKDDIVILDSLNYIKGYRYELFCLIKHTQTPHCLVYSLTS-----------------ADLSSEWNK----------------------------------DREADSQYT--------------------------QEILDALILRFEAPDSRNRWDSPLFTIQ-QDDSLP--FEAICDALFKRKAPP---------------PNQSTKSQPLSSTNFLYELDKVTQDVLMAVLESQK-------TSVPGDLISIPGATEK---------IELTRSLNMVELRKLRRQFISYT--KMHP-TENIGQIANMFVQYLNKSMH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46079-1", "uniprot_id": "O46079_DROME", "id": "O46079-1", "name": "Protein KTI12 homolog", "aln": "MPLVVITGLPASGKSTRARQLRDHFVE-RGRKVHLISE--NEAVPKAGFGKNSHTGDSQKEKVVRSDLKSEASRHLNQEDLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIP-------------------QEEAWTFNSQRTAPDELPG------------------DSERVQPVDNSDVPYT-----------------------RETFDALCQRYEEPQSNNRWDSPLVVVL-PKDTLD--MEAIYKALYESQPLP---------------PNQSTYNAPLGTTNYLFELDKIVQAIIKEILGAVK-------IKAFG-QLRIPGSRNP---------VKVATSMNALQLNRLRQKFITSTCHASQTSPTPLEQVPHLFVQFINANTIGC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34253-1", "uniprot_id": "KTI12_YEAST", "id": "P34253-1", "name": "Protein KTI12", "aln": "MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHSDESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVKNLSTTFCVIQTLCP-----------------PETIFEWNKTSNPNP-------------------------------------------------------------WEPELLNQLIQRYEEPNSSNRWDSPLFAILTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQVLDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTLAQLQRLKRQFINFN----KLRDIDQDRIGPLFADYLNKNLN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::. * * ***: :..* : . : . : * *: :*. : : ..* :.:..:**:*: *****:**:*.* : *. * : . * * :: * *:* *:* **** **..: .: : : * ..::: . *:.:* * . .:: ** .. :: :: * : * : : . :. :* :*:::**. . : :: :* :::. . ", "identical_positions": 53, "similar_positions": 86, "identity": "13.35%" }, { "cls_id": "homologset.agr.SGD:S000001596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIP6-1", "uniprot_id": "FEN1_RAT", "id": "Q5XIP6-1", "name": "Flap endonuclease 1", "aln": "MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQ-GGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYIFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGAEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESVRGIGPKRAVDLIQKHKSIEEIVRRLDP-----SKYPVPENWLHKEARQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLNKSRQGSTQGRLDDFFKVTGS----LSSAKRKEPEPKGPAK-KKAKTGG-AGKFRRGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39749-1", "uniprot_id": "FEN1_MOUSE", "id": "P39749-1", "name": "Flap endonuclease 1", "aln": "MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQ-GGDVLQNEEGETTS-LMGMFYRTIR-MENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGAKRAVDLIQKHKSIEEIVRRLDP-----SKYPVPENWLHKEAQQLFLEPEVVDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGS----LSSAKRKEPEPKGPAK-KKAKTGG-AGKFRRGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39748-1", "uniprot_id": "FEN1_HUMAN", "id": "P39748-1", "name": "Flap endonuclease 1", "aln": "MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQ-GGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDP-----NKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGS----LSSAKRKEPEPKGSTK-KKAKTGA-AGKFKRGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TNU4-1", "uniprot_id": "FEN1A_DANRE", "id": "Q6TNU4-1", "name": "Flap endonuclease 1", "aln": "MGIHGLAKLIADHAPSAIKEHEIKSYFGRKIAIDASMCIYQFLIAVRQ-DGNVLQNEDGETTSHLMGMFYRTIRMLESGIKPVYVFDGKPPQLKSGELEKRVERRAEAEKLLAQAQEAGEQENIDKFSKRLVKVTKQHNEECKKLLSLMGVPYIEAPCEAEASCAALVKAGKVYATATEDMDGLTFGTTVLLRHLTASEAKKLPIQEFHFSRILQDMELTHQQFIDLCILLGCDYCGTIKGIGPKRAIDLIKQHGSIEEILENIDP-----NKHPAPEDWLYKEARGLFLEPEVVDGTSVDLKWNEPDEDGLIQFMCAEKQFSEDRIRNGCKKITKSRQGSTQGRLDTFFTVTGS----ISS-KRKEPETKGSAK-KKQKTSATPGKFKKGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K7A9-1", "uniprot_id": "FEN1_DROME", "id": "Q7K7A9-1", "name": "Flap endonuclease 1", "aln": "MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRS-EGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGDDAGIEKFNRRLVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYLTYSEARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCESIKGIGPKRAIELINTYRDIETILDNLDS-----SKYTVPENWNYKVARELFIEPEVADADSIDLKWVEPDEEGLVKFLCGDRQFNEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPSTPNATNAAKRKAEEAKKSANNKKAKTSG-GGRGRRPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26793-1", "uniprot_id": "FEN1_YEAST", "id": "P26793-1", "name": "Flap endonuclease 1", "aln": "MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLIAVRQQDGGQLTNEAGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRSSRRVETEKKLAEATTELEKMKQE---RRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTIEQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPEDWPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISRLKKGLKSGIQGRLDGFFQVVPKTKEQLAAAAKRAQENKKLNKNKNKVTKG-----RR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** :*:: .*.**:: ::* :****:******.:********. * * . *:.** ********:* ::.**** *:******:*** ** ** .** *:** * * . : :***:*:*:* .*.:.** ***:**: ** ****.** *.* *****:*:**** * : :. *:*:** ***:* *::*: . :*. : :. .:*:****:**.*** :::*:*. *:.**: : .** *: ::. .* **:* :* *: **::*** * .::*** *.*. *::::* :::*.*:*::.* .:: *. :. * *** ** . . : :: * * : *: * . :: ", "identical_positions": 165, "similar_positions": 114, "identity": "42.09%" }, { "cls_id": "homologset.agr.SGD:S000001597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32U4L1-1", "uniprot_id": "A0AB32U4L1_DANRE", "id": "A0AB32U4L1-1", "name": "", "aln": "MGETLAAICLEACSWQGRVVGQALRPSTRPFPRKKSMASRRKGEKKKKTVELTEAKKQQHLDAEPSDGSTKEQMACKRKMKPQKKYIGAHVSISGGIWKAVESSVAMGGHAFALFLGSQRSWTRPVLDSKAAVKFQQACAEHGFDPVH-ILPHGSYLMNCGSPKEDVFSKSQAMLVDELSRCDALGLSQFNFHPGAAMDSSPEKCMEKIAQAINHAHQQTPAVITVLENMSGQGSTIGGQFSELKGIIDRVRDKTRVGVCLDTCHAFAAGYDISPPGGVKNMLDEFDRVVGLHYLRAVHLNDSKGKLGSHLDRHEDIGHGQIGITAFQEIVNEPRLDNIPLILETPGRQGFEYAEQIELLYSLCEKKVKK-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22936-1", "uniprot_id": "APN1_YEAST", "id": "P22936-1", "name": "Apurinic-apyrimidinic endonuclease 1", "aln": "------------------------MPSTPSFVRS----------------------------------------------AVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQKKRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** .* *. .* :***:* :*** ::* .:. * ::**:** * *.*. * .: **:: ** :.::*: :****.*::* ..*..: .** ::*:*.**: **:. :*:***:::... : ::::*. :*:* ::* * *****:* *. :*..: :** :*. :.**:*:***:****:********.. .:*: .**: *:*::** ********. **:: * ** :*:* :** .*: *.:. *:.**::**** .:. *.::*:*: * .*. .: ", "identical_positions": 119, "similar_positions": 112, "identity": "27.23%" }, { "cls_id": "homologset.agr.SGD:S000001600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83868-1", "uniprot_id": "TEBP_RAT", "id": "P83868-1", "name": "Prostaglandin E synthase 3", "aln": "---------------------------------------------MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSC----LGGSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMDHMGGDEDV--------------------------------DLPEVDGADDDSQDSDDEKMPDLE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q7-1", "uniprot_id": "TEBP_MOUSE", "id": "Q9R0Q7-1", "name": "Prostaglandin E synthase 3", "aln": "---------------------------------------------MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSC----LGGSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMDHMGGDEDV--------------------------------DLPEVDGADDDSQDSDDEKMPDLE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15185-1", "uniprot_id": "TEBP_HUMAN", "id": "Q15185-1", "name": "Prostaglandin E synthase 3", "aln": "---------------------------------------------MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSC----LGGSDNFKHLN-EIDLFHCIDPNDSKHKRTD--RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDR-----FSEMMNNMGGDEDV--------------------------------DLPEVDGADDDSQDSDDEKMPDLE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D9A7-1", "uniprot_id": "PTG3L_MOUSE", "id": "Q9D9A7-1", "name": "Putative protein PTGES3L", "aln": "-------------------------------------------MERQPARTLWYDRPKYVFMEFCVEDSTDVSVLIEDHRVVFSC----RNG-DGVELYN-EIEFYAKVNSKDSQDKRSG--RSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDDEVELAQVEH-----YAE----------------------------------------------------DDSDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJ40-1", "uniprot_id": "A0A8I6AJ40_RAT", "id": "A0A8I6AJ40-1", "name": "", "aln": "-----------MAPHTTLWSPPSTFPYCLQSCPP--LPSPTSNLFRQHARTLWYDRPKYVFMEFCVEDSTDVSVLIEDHRIVFSC----RNG-DGVELYN-EIEFYAKVNSKDSQDKRSG--RSITCFVRKWKEKVPWPRLTKKDIKPVWLSVDFDNWRDWEGDDEMELAQVEH-----YAELLNKVSTKR----------------------------------PPPAMDDLDDDSDN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PB15-1", "uniprot_id": "PTG3L_HUMAN", "id": "E9PB15-1", "name": "Putative protein PTGES3L", "aln": "MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYVFMEFCVEDSTDVHVLIEDHRIVFSC----KNA-DGVELYN-EIEFYAKVNSK-----------------------------------PVWLSVDFDNWRDWEGDEEMELAHVEH-----YAELLKKVSTKR----------------------------------PPPAMDDLDDDSDSADDATSN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28707-1", "uniprot_id": "SBA1_YEAST", "id": "P28707-1", "name": "Co-chaperone protein SBA1", "aln": "----------------------------------MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKPSYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESEYWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAGGMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VH95-1", "uniprot_id": "TEBPH_DROME", "id": "Q9VH95-1", "name": "Cytosolic Prostaglandin E synthase", "aln": "---------------------------------------MSAAAGLIPPPVSWAQRNDLIYVIIDV-ECKDIEHKVTEKTFTFKG----VNVLDPSKKYEVTLNFLHEVDPEKVTSKNIG--RCLEFTIPKKAAGPYWSSLTTDKTKLHFLKANFAKWRDESDDEEGDQKDNSM-----FGNFLNSPGGDWNNKFDDFN----------------VDDEEEDSDDNIPSLSQNDEDDEEGGEGDKEKKPAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : :. . . :. : . : ::: : .: ::..:* :* * . :.: : . :.: :*.:. ", "identical_positions": 4, "similar_positions": 39, "identity": "1.59%" }, { "cls_id": "homologset.agr.SGD:S000001603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z9L9-1", "uniprot_id": "A1Z9L9_DROME", "id": "A1Z9L9-1", "name": "Solute carrier family 25 member 35", "aln": "----------------------MATSDFVLGGVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQPYKSVFQAFVTVAKNDGILGLQKGLAPALCFQFVINSFRLSIYTHAVEKGWVHNN-----KGEISFAKGMFWGALGGVVGSYCASPFFLIKTQLQAQAAKQIAVGYQHQHASMSDAIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLLKENGVVT-HPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPYSTLVLLFFDELIALREKYDLHY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9M0-1", "uniprot_id": "A1Z9M0_DROME", "id": "A1Z9M0-1", "name": "Solute carrier family 25 member 35", "aln": "----------------------MTKSDFVLGGTAAMGAVVFTNPIDVVKTRMQLQGELAARGTYVKPYRHLPQAMLQIVLNDGLLALEKGLAPALCYQFVLNSVRLSVYSNALELGYLQNA-----DGSISFYRGMFFGALGGCTGTYFASPFYMIKAQQHAQAVQSIAVGFQHKHTSMMDALLHIYRTNGISGFWRAALPSLNRTLVASSVQIGTFPKAKSLLKDKGWIT-HPVLLSFCAGLSSGTLVAVANSPFDVLTTRMYNQPVDEKGRGLMYKGLVDCFTKIWRTEGIHGMYKGFWPIYFRSAPHTTLTFVFFEKLLHLRDRYVFSQRRN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3KQZ1-1", "uniprot_id": "S2535_HUMAN", "id": "Q3KQZ1-1", "name": "Solute carrier family 25 member 35", "aln": "-------------------------MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTA-----EGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKGLMYRGILDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFWDQLRSLYYTDTK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SWT3-1", "uniprot_id": "S2535_MOUSE", "id": "Q5SWT3-1", "name": "Solute carrier family 25 member 35", "aln": "-------------------------MDFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFLMNGIRLGTYGLAESRGYLHTN-----EGTHSPVRSAAAGALAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFYNTYAK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L7L9-1", "uniprot_id": "A0ABK0L7L9_RAT", "id": "A0ABK0L7L9-1", "name": "", "aln": "-------------------------MDFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFLMNGIRLGTYGLAESGGYLRTK-----EGTHSPVRSAAAGALAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSTKDLLSQWEIFPPQSWKVALAAAMVSGVAVVLAMTPFDVASTRLYNQPTDTRGKVLS-------ILETHRIQSIK-LHTTEPSHLFYLAKVNSLQVPTGEMLGEWGGPTTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KPP4-1", "uniprot_id": "S2535_DANRE", "id": "A3KPP4-1", "name": "Solute carrier family 25 member 35", "aln": "-------------------------MDFILGGVAACGACFFTNPLEVVKTRMQLQGELKSRGTYQVYYRNVFHAFYTIGKIDGLAGLQKGLVPGLVYQFFMNGVRLGSYALTESLGYIHT------DGRVSATKSTVSGAIAGVVGAVMGSPIYLVKTHLQSQSTSSIAVGHQYKHRGMTNALFAIHKQHGILGLWRGASAAIPRVSVGSAAQLATFSASKEMVNDLQVFSEGSWLIALSAGMISSVVVVLAMTPFDVVSTRLYNQPVDHLGKGMLYRGFVDCFSKTLKKEGMTGLYKGLGASYFRLGPHTILSLLFWNELRCLHQSYS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5XIF9-1", "uniprot_id": "S2534_RAT", "id": "Q5XIF9-1", "name": "Solute carrier family 25 member 34", "aln": "----MTLTQAQMAPATDSREMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVTAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAG-----------LTQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTGAAVAVGHQHQHQGVLSALETIWRQQGMLGLWRGVGAAVPRVTVGSAAQLATFTSAKAWVQDQQWFLEDSWLATLAGGMISSIAVVAVMAPFDVVSTRLYNQPVDRAGRGQLYGGLTDCLVKTCQQEGPLALYKGVGPAYLRLGPHTILSMFFWDELRKLALRAQHPGT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ADF7-1", "uniprot_id": "S2534_MOUSE", "id": "A2ADF7-1", "name": "Solute carrier family 25 member 34", "aln": "----MKPTQAQMAPAMDSREMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAG-----------LTQQPGGTVVAGAAAGALGAFVGSPAYLVKTQLQAQTVATMAVGHQHQHQGVLSALETIWRQQGMLGLWRGVGGAVPRVTVGSAAQLATFTSAKAWVQDRQWFLEDSWLVTLAGGMISSIAVVAVMTPLDVVSTRLYNQPVDRAGRGQLYGGLADCLVKTCQQEGPLALYKGLGPAYLRLGPHTILSMFFWDELRKLVARAQHQGT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIV7-1", "uniprot_id": "S2534_HUMAN", "id": "Q6PIV7-1", "name": "Solute carrier family 25 member 34", "aln": "------------------METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAG-----------LTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAGRAQHKGT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH61-1", "uniprot_id": "S2534_DANRE", "id": "Q6PH61-1", "name": "Solute carrier family 25 member 34", "aln": "MNSAFSGPSSPTPGPSPPRPPLWPPLDFGLGALACCGACVFTNPLEVVKTRLQLQGELRARGSYRRLYRGVLQALWVVGRTDGLRGLQKGLTAALLYQGLMNGLRLGSYAQMQAAG-----------VTDGPCCSLIAGAAAGALGAFIASPAYLVKTHLQAQTVAAIAVGHQHNHQGMSSALVSIYRREGVCGLWRGVNGAVPRVMVGSATQLATFSSAKDWITHTQWFSPLSSLNTLCAAVMSGVAVSIIMTPFDVISTRLYNQPVDQFKQGRLYCGFVDCLLKVCAAEGVLGLYKGMTPVFVRLAPHTTLSMLLWDVLRQRALPYTH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32332-1", "uniprot_id": "OAC1_YEAST", "id": "P32332-1", "name": "Mitochondrial oxaloacetate transport protein", "aln": "--MSSDNSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSA--SAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQS-YSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMK-DGPALHLTASTISGLGVAVVMNPWDVILTRIYNQ------KGDLYKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESRVLGHN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .. *. * .***::::* *:*****: : : *: .. : :*: .*:*** .. :* :*. *: * ** .* *: .** :::*:: :: : :* * :: : .: * : .*: *:::. : *. .*:.*: : * : . . : .. :. : * ** **:*** : . :. ::. . . . . : . : ", "identical_positions": 46, "similar_positions": 83, "identity": "13.69%" }, { "cls_id": "homologset.agr.SGD:S000001604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R037-1", "uniprot_id": "WDR44_RAT", "id": "Q9R037-1", "name": "WD repeat-containing protein 44", "aln": "---MMP----------LKMCTWGGSYPVG---------------SPGKVGLLSFKETKNTGNKAGN---ESPVQELRQDVSKKIIECIIE--------------ESQKVLQLEDD-------SLDSKGKG----LSDQATASHSVAGTEFSNIPGLLAIQHE------------LQQGSRKADSQNAAEETE--LETQKCFPSDNNCEKSEKTEDETNN--------LTEVSSADQLDASKLETEILNKEAVEVKEG-DVVNP----ASSDALSTKDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKKKSDLEFEALKTPDLDVPKDNIASDSLLTTNMASESTVRDSLPSLDLASATSGDKIVTAQ-----------------------ENGKAPDVQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGINPLTPLTLHIMRRTKEYVSNDATQSDD-----EEKLQSQQTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDNTSTGIVKTDNTEVLLSADFTGAQCFYVKNSFLYP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVE8-1", "uniprot_id": "WDR44_MOUSE", "id": "Q6NVE8-1", "name": "WD repeat-containing protein 44", "aln": "---MASESDTEEFYDAPEDVHLGTGYPVG---------------SPGKVGLLSFKEAENTANQAGN---ESPVQELRQDVSKKIIESIIE--------------ESQKVLQLEDD-------SLDSKGKG----LSDEATAGPSVAGTEFSNIPGLLAIEHE------------LQQDSEKAESQNVAEESE--LETQKCFPSDETCEKSEKTVDETDN--------LTEVSSGEQLDASGLEAETLNKEALEVKEG-DVLDP----ASLDTLSTTDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKKKSELEFEALKTPDLDVPKENITSDSLLTTNMASENTVRDSLPSLDLASATSGDKIVTAQ-----------------------ENGKAPDVQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGIN---PLTLHIMRRTKEYVSNDATQSDD-----EEKLQSQQTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDSTSTGIVKTDNTEVLLSADFTGAIKVFINKRKTVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JSH3-1", "uniprot_id": "WDR44_HUMAN", "id": "Q5JSH3-1", "name": "WD repeat-containing protein 44", "aln": "---MASESDTEEFYDAPEDVHLGGGYPVG---------------SPGKVGLSTFKETENTAYKVGN---ESPVQELKQDVSKKIIESIIE--------------ESQKVLQLEDD-------SLDSKGKE----LSDQATASPIVARTDLSNIPGLLAIDQV------------LPEESQKAESQNTFEETE--LELKKCFPSDETCEKP---VDETTK--------LTQTSSTEQLNVLETETEVLNKEAVEVKGGGDVLEP----VSSDSLSTKDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDSQPSLDLASATSGDKIVTAQ-----------------------ENGKAPDGQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGIN---PLTLHIMRRTKEYVSNDAAQSDD-----EEKLQSQPTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSGIMKTDNTEVLLSADFTGAIKVFVNKRKNVS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMK1-1", "uniprot_id": "Q8IMK1_DROME", "id": "Q8IMK1-1", "name": "WD repeat-containing protein 44", "aln": "MSKLETDSDSSEEFFDAEDTTPNRHSTLCRKLPPEVAQEFIFPEPAVRVNAAASSDSDATPIGAGTPATRSPTNSLGARLKPQDAGVFVEPKPVIGPLGRQRFHELRQCMQNDEDDNPGNTLTPDSQNSSTDGIFTNRSTHPFKVIETDAMSIQSMTSLGRVGRILAGSIDPSAISIDRESLASLNAQQQKQQAQQQQQAQPTSSTSSNTPPSVGNTSSGMSTPRVSPKHQQSGKEVAATTTGIPSAASSAQSSGVGSMVLQEPDVIASTKLAQSKTTDSITSSGPVAPPRRKKKSRNCSISSSDQYSLPPADNEDTDSDTRSVKSVQGLQQKLRDDFVMEFESSLNNATSSASNITLTCSSTNTVVSASASTSAASSSLPSTIAIHMRPMVASVTIAGPKLTQSLGSSSTSVHSKPSPSNSAKSNSAPARVSSIDPNQGLNLFKAIQGGYVVKPRDEASNKAQGPSQDEIERIEKMLMESANRPKLAGTGSNSLGSSTRYPGFYRGVNDKERRKSAGDEDVLKQMNIYVRTRTSSGKQLTDFEILEQVPVKNLDTGENMPLSEMRSPPVPEGWN---PLSLHILKLTSHLEVIQKESDEESVIGIPPSIEGQQPDEEELETEDGSRLKKKTARIKRFFGSTMR-----------KTVDKAKSIASEVSHARHKEDVADIVDAMNPEQNIKIKASSSNKGPYEFTKLQHVQDLSGEDTSAVWCMKFSSCGRLLATAGQDKVLRIWVLKDAYPFFQDMRNKYNADQKSSPTPSQESLVSQHSAEEAIAMATAAEKCTG---PFMPKPFCTYNGHTSDLLDVSWSKNYFILSSSMDKTVRLWHISRKECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYDGRCIFYNTDQLKYHTQIHVRSTRGKNRIGRKISGIEPMPGEDKILVTSNDSRVRLYDLRDLNLSCKYKGYLNVSSQIKGSFSHDGKYIIAGSENQCIYIWKTNHDYSKLSSVRRDRSDFWEGIKAHNATVTCAIFAPHPEAIIKPEPDEISNEKLAHNQPDPLVEQHKKGCG-----YVLVSADFNGAIKVFINKTKPKHSSLPYTAIAD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32330-1", "uniprot_id": "DGR2_YEAST", "id": "P32330-1", "name": "2-deoxy-glucose resistant protein 2", "aln": "---MFKSKTSTLSYDETPNSNEGDRNATP-------------------VNPKEKSQTKHLNIPGDR-SRHSSIADSKRSSSRYDGGYSAD--------------IIPAQLRFIDN------IDYGTRLRKT---LHRNSVVSNGYNKLSENDRWYFDLFDRK-----------YFENYLEEPTYIKIFKKKEGLEQFDRMFLAQELKIPDVYKSTTYQG---------EPAVANSELFKNSICCCTFSHDGKYMVIGCKDGSLHLWKVINSPVKRSEMGRSEKSVSASRAN----------------SLKIQRH------------------------------------------LASISSHNGSISSND-LKPSDQFEGPSKQLHLYAPVFYSDVFRVFMEHALDILDANWSK----NGFLITASMDKTAKLWHPERKYSLKTFVHPDFVTSAIFFP-------------------------NDDRFIITGCLDHR------------------------------------CRLWSILDNEVSYAFDCKDLITSLTLSPPGGEYTIIGTFNGYIYVLLTHGLKFVSSFHVSDKSTQGT------TKNSFHPSSE-----YGKVQHGPRITGLQCFFSKVDKN---------LRLIVTTNDSKIQIFDLNEKKP-------LELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDDHWFYTWKMQSFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSSSHTFTNSSKNVLQTQTVG-----SQAIKNNHYISFHAHNSPVTCASIAPDVAIKNLSLSN----------------DLIFELTSQYFKEMGQNYSES-----KETCDNKPNHPVTETGGFSSNLSNVVNN----VGTILITTDSQGLIRVFRTDILPEIRKKIIEKFHEYNLFHLEAAGKINNHNNDSILENRMDERSSTEDN-EFSTTPPSNTHNSRPSHDFCELHPNNSPVISGMPSRASAIFKN--------SIFNKSNGSFISLKSRSESTSSTVFGPHDIPRVSTTYPKLKCDVCNGSNFECASKNPIAGGD-----SGFTCADCGTILNNFR-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *. .::. . .*. . . : :: :: .:: : .:. . . : : : : .. : ::.: : .: :.. : .:: .. * . . . . . . .. .. * . :* : :.: .. . . . .:* . . . .. : . . .. .* . . :... . :. .: * *: . *:* *. :. . : . * * :: .. : . . . : .. . : : : :: *:.. : : : ..:. :: . ... : : .: :: : : * *.:. .* *: . : :. .. *: . :. : * . : : :..*.* : . . : : .: . : .::.*.: : * : : : . *:.: : * :*: *: .:.* * * * *:: *: . ...: . :. * : :* .: *: * : :.. : * . : :* .::.** . *.* * ::. : : : . .*: .: : . :::* .: *:.. *: .. .. : .:*::. .:.::*.*: :. . . : : . * : .** : ", "identical_positions": 56, "similar_positions": 277, "identity": "4.96%" }, { "cls_id": "homologset.agr.SGD:S000001608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NYV6-1", "uniprot_id": "RRN3_HUMAN", "id": "Q9NYV6-1", "name": "RNA polymerase I-specific transcription initiation factor RRN3", "aln": "MAAPLLHTRLPGDAAASSSAVKKLGASRTGISNMRALENDFFNSPPRKTVRFGGTVTEVLLKYKKGETNDFELLKNQLLDPD-----IKDDQIINWLLEFRSSIMYLTKDFEQLISIILR--LPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIIKEGDVDVSDSDD--EDDNLPANFDTCHRALQIIARYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISVYFPTLRHEILELIIEKLLKLDVNAS--------------RQGIEDAEETATQTCGGTDSTEGLFNMDEDEETEHETKAGPE------------------RLDQMVHPVAERLDILMSLVLSYMKDVCYVDGKVDNGK---TKDLYRDLINIFDKLLLPTHASCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPSNPAIIRQAAGNYIGSFLARAKFIPLITVKSCLDLLVNWLHIYLNNQDSGTKAFCDVALHGPFYSACQAVFYTFVFRHKQLLSGNLKEGLQYLQSLNFERIVMSQLNPLKICLPSVVNFFAAITNKYQLVFCYTIIERNNRQMLPVIRSTAGGDSVQICTNPLDTFFPFDPCVLKRSKKFIDPIYQVWEDMSAEELQEFKKPMKKDIVEDEDDDFLKGEVPQNDTVIGITPSSFDTHFRSPSSSVGSPPVLYMQPSPL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NIE6-1", "uniprot_id": "RN3P2_HUMAN", "id": "A6NIE6-1", "name": "Putative RRN3-like protein RRN3P2", "aln": "MAAPLLHTRLPGDAAASPSAVKMLGASRTGISNMRALENDFFNSPPRKTVQFGGTVTEVLLKYKTGETNDFELLKNQLLDPD-----IKDDQIINWLLEFRSSIMYLTKDFEQLISIILR--LPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIIKEGDVDVSDSDD--EDDNLPANFDTS----QSLANNS--------------------KICTIECYVHNLLRISVYFPTLRHEILELIIEKLLKLDVNAS--------------RQGIEDAEETANQTCGGTDSTEGLCNM---------------------------------------------------------------------------------------------------------------GFAEAFLEPLWKKLQDPSNPAIIRQAAGNYIGSFLARAKFIPLMIRE---------------------------------------------QRHSAMLLS------------------MDHFT----------------------------------------------QPAKLCSTPL----------------FLD------------------------------------------------TSSF-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RS91-1", "uniprot_id": "RRN3_MOUSE", "id": "B2RS91-1", "name": "RNA polymerase I-specific transcription initiation factor RRN3", "aln": "MAAPLLHTRLSGDVTAAASAT--LSASRTGLSDMLALESDFFNSPPKKTVRFGGTVTEVLLKYKKGETNDLELLKNQLSDPD-----IKDDQIINWLLEFRSSVMYLTKDFEQLINIILR--LPWLNRSQRVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIVKEGGIDVSDSDD--EDDNLPAIFDTCHRALQIITRYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISLYFPTLRREILELVIEKLLKLDVSVS--------------RQDIEDAEEKAAQTCGGTDTTEGLFNMDEDEDTDPEKKADQE------------------QPNQMAHPTAERLDVLLCLLLSYIEDVCRVHGKIDNNK---TKDLYRDLISIFDKLLLPTHASCHVQFFMFFLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKTCLDLLVNWLHMYLTNQDSGTKAFCDVALHGPFYSACQAVFYTVVFRHKQLLSGNLKQGLQYLQSLNFERIVLSQLNPLKICLPQVVNFFAAITNKYQLVFCYTIMERNSRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCVLKRSKKFIDPIYQIWEDGSAEELQEFKKSTKKEVVEDEDDDFLKGEVPQSDTVTGLTPSSFDTHFQSPSSSVGSPPVLYIPGQSPLLTRIYD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8U0-1", "uniprot_id": "A0A0G2K8U0_RAT", "id": "A0A0G2K8U0-1", "name": "", "aln": "MAAPLLHTRLSSDVAATGSAT--LSASRTGLSNMLALESDFFSSPPRKTVRFGGTVTDVLLKYKKGETNDLELLKNQLSDPD-----IKDDQIINWLLEFRSSVMYLTKDFEQLINIILR--LPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIVKEGGIDVSESED--EDDNLPANFDTCHKALQIITRYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISLYFPTLRREILELIIEKSLKLDVSVS--------------RQDIDDAEETAAQTYGGTDAAEGLFNMDEDEETDPEKKAEQE------------------RPGRMAHPTAERLDILLSLLLSYIDDVCHVQGKIDNNK---TKDLYRDLISIFDKLVLPTHASCHVQFFMFFLCSFKLGFAEAFLEHLWKKLQDPNNPVIIRQAAANYIGSFLARAKFIPLITVKSCLDLLVNWLHLYLNSQDSGTKAFCDVALHGPFYSACQAVFYTVVFRHKQLLSGNLKEGLRYLQSLNFERIVLSQLNPLKICLPRVVNFFAAITNKYQLVFCYTIMERNNRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCMLKRSKKFIDPVYQAWEDMSDEELQELRKPTRKELVEDEDDDFLKGEVPQSDTVAGLTPNSFDTHFRSPSSSVGSPPVLFMPDQSSLLSRICD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M238-1", "uniprot_id": "RN3P1_HUMAN", "id": "Q2M238-1", "name": "Putative RRN3-like protein RRN3P1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFAEAFLEHLWKNLQDPSNPAIIRQAAGNYIGSFLARAKFISLITVKPCLDLLVNWLHIYLNNQDSGTKAFCDVALHGPFYSACQAVFYTFVFRHKQLLSGNLKEGLQYPQSLNFERIVMSQLNPLKICLPSVVNFFAAIT------------------------------KMKTCGYGWW-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ICI5-1", "uniprot_id": "A0A0R4ICI5_DANRE", "id": "A0A0R4ICI5-1", "name": "", "aln": "---------------------------------MEIEGRDFINTPPLKTVRFGGTVANTLAKLQKGDTSDYELIKHQLSDPD-----IKDAQIINWLQEFRTCVTQLGKDHEQLVYVVLK--LPWLGRSQAVVEEYLAFLSNLVSAQTVYLRACLRMVVTNFSPKRIRIQEGNVDISDSDD--EDENLPRTFDNCHQALQLIARYVPSTSRFLMPILTDKFPFVQKSSRTLECYVHNLLRVTVYIPDLRKDVLELIISKMLMLDVSAP--------------RSEIEEVESGAQQGASGASQDDCLFNMDEEEDSPLSSGADG---------------------GAMVHPVAERLDTMMTVLLAYIKDVSHVNGTLDIEK---TKALYRDLVSVFDKVVLPTHASCHVQFYMFYLCSFRLGLAEAFLDHLWKLLQGPNQPSVLRQSAAGYMGSFMARAKFLPVSTVKACLDLLVPWLHLYIDSQDSGSKAFCDINLHGPFYTACQAVFYTLIFKHNAILEGNMKKGLAYLQGLNLERIVMCQLNPLRVCLPAVTNMFAAITRKYQLVFCYTIIERNNRHLLPVVRSSVGGSSVATNTNPLDSFFPFDPYLLKSSGKLIEPIYQVWEEPSDCMIGVPKKEIPKGSMEEEDD-FLHGETPHGDSIVGMTPGSYESHLQSPRS-VGSPPISFLQRPF--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9M6-1", "uniprot_id": "RRN3_DROME", "id": "Q9V9M6-1", "name": "RNA polymerase I-specific transcription initiation factor Tif-IA", "aln": "-------MSFYTSKTDVTSILKTFSGVKRNQANAVAINKVRFSTPKEK-----GLAESVRVALEERNFHLVKEFTYFLREAE-----LSDDEVVIIIKDAKRIVHNLTPEFVTVVEALLS--LNWKKRSSEIIEAYTEFCIELMVTHNRYLPIGVSKLIVHWIP-------GDMDESDWVHGCPSEHVRNELKPIHKVLDRILTAVPMAFDIIIDAISAKFPYFKKPYHVTAGYLYNVLWLLEYKPIFEELVFQLVLQKLLLLDVNAP--------------KDEIELEMNDEEE----KVEADTLFEIDDVCAENVPKSEKS-----------------------VSHPVGKTLDVCLFLLYKFFDGKCRLNENSSEEQRRTANRLFKMLLYLFDEVLLPSHNTHHVQFILFYATSLRSVYSEAFLDSLWTKVQNPNVSAVIRHAAVGYMASFLSRARFLPLSTVTFYLKELTRWAHTYIDDSDAYKQN-CSLKANLVFYSVCQAVFYLIAFRAKDLTASS--KDLLFLQSLQLSRLAMCHLNPLRYCLAPVATAFAGVTRTYQLAYCHTVLERNARRKLATVYG----HEKCMPDETLESFFPFDPYVLKLSKKYIETNYMVYQSNDTDEYVYGSNKYGHSRKRGDSEMLEEDEFLIVDKRPKNFDLSKSQEFDKQFHFGSSP-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36070-1", "uniprot_id": "RRN3_YEAST", "id": "P36070-1", "name": "RNA polymerase I-specific transcription initiation factor RRN3", "aln": "MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKDEVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSSNINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVSCFILP-----------------------IKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKLRGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSGDDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDSILTLVSTHVEEQVTPESLESGEG----VGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQLELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWLNRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDG--NWECELDKFFQRMVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIG---KADSDKKENSAQANTTSSSWSLATRQQFID---------------------LQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDGSDD----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** * . . : : *:.*:::**: :. : . : : ::. ", "identical_positions": 7, "similar_positions": 21, "identity": "1.0%" }, { "cls_id": "homologset.agr.SGD:S000001609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4U9-1", "uniprot_id": "SGK2_RAT", "id": "Q8R4U9-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPVGV----PSP----------QPSRANGN----------------------------------------------------------------------------------------------------------------------------INLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIG---CTPDT---MSSSSGASSAFLGFSYAQDDDDILDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS5-1", "uniprot_id": "SGK2_MOUSE", "id": "Q9QZS5-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPVGV----PSP----------QPSRANGN----------------------------------------------------------------------------------------------------------------------------INLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIG---CTPDT---VASSSGASSAFLGFSYAQDDDDILDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBY8-2", "uniprot_id": "SGK2_HUMAN", "id": "Q9HBY8-2", "name": "Serine/threonine-protein kinase Sgk2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSSPAGT----PSP----------QPSRANGN----------------------------------------------------------------------------------------------------------------------------INLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIG---CTPDT---VASSSGASSAFLGFSYAPEDDDILDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERE3-1", "uniprot_id": "SGK3_MOUSE", "id": "Q9ERE3-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "----------------------------------------------------MQRDCIMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPD-----FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQ----SDPSEDEDERSTSKPHSTSRN----------------------------------------------------------------------------------------------------------------------------INLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4V0-1", "uniprot_id": "SGK3_RAT", "id": "Q8R4V0-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "----------------------------------------------------MQRDCTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPD-----FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQ----SDPSEDEDERSTPKPHSTSRN----------------------------------------------------------------------------------------------------------------------------INLGPTGNPHAKPSDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BR1-1", "uniprot_id": "SGK3_HUMAN", "id": "Q96BR1-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "----------------------------------------------------MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPD-----FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQ----SDPSEDEDERSSQKLHSTSQN----------------------------------------------------------------------------------------------------------------------------INLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVC6-1", "uniprot_id": "SGK1_MOUSE", "id": "Q9WVC6-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-------------------------------------------------------------------MTVKAEAARST--LTYSRMRGMVAILIA-----------------------------------------------FMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEPELMNANPS---------PPPSPSQQ----------------------------------------------------------------------------------------------------------------------------INLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIG---RSPDSILVTASVKEAAEAFLGFSYAPPVDSFL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06226-1", "uniprot_id": "SGK1_RAT", "id": "Q06226-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-------------------------------------------------------------------MTVKTEAARST--LTYSRMRGMVAILIA-----------------------------------------------FMKQRRMGLNDFIQKLANNSYACKHPEVQSYLKISQPQEPELMNANPS---------PPPSPSQQ----------------------------------------------------------------------------------------------------------------------------INLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK-NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIG---RSPDSILVTASVKEAAEAFLGFSYAPPMDSFL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00141-1", "uniprot_id": "SGK1_HUMAN", "id": "O00141-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-------------------------------------------------------------------MTVKTEAAKGT--LTYSRMRGMVAILIA-----------------------------------------------FMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPS---------PPPSPSQQ----------------------------------------------------------------------------------------------------------------------------INLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIG---KSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTW4-1", "uniprot_id": "SGK1_DANRE", "id": "Q7ZTW4-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-------------------------------------------------------------------MTIQTETSVSAPDLTYSKTRGLVANLSA-----------------------------------------------FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTPPQDVELMNSNPS---------PPPSPSQQ----------------------------------------------------------------------------------------------------------------------------INLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIG---CSPDSALVTSSITEATEAFLGFSYAPAMDSYL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQL0-1", "uniprot_id": "A0A8M3AQL0_DANRE", "id": "A0A8M3AQL0-1", "name": "non-specific serine/threonine protein kinase", "aln": "------------------------------------------------------------------------MVKKAKSPVTYAKMKGIVSYFTA-----------------------------------------------LIKDKKL----------RSSHPIYHHFYHSRMDFLRPEGS---LSDDD---------RATAVCYS----------------------------------------------------------------------------------------------------------------------------NPVREEPQSQVSAGDFDYLKVIGTGSFGKVFLATHRENGKYYAVKVLQKHIILTRKEERNVMCEHRVLLKTLNHPFLVKLHFSFQTKERLYLVLDYACGGELFYHLQREGVFGEARARFYAAEMACALGYLHSLKIVYRDLKPENILLDSAGHVVLTDFGLCKEGMSGRGTTRTFCGTPEYLAPEVLLQEEYDRTVDWWGLGAVLHEMLYGLPPFYNADRLEMLRNIIYQPLALKAGVSSAARDLLKRLLNRDRAKRLGAKRDLIELQSHAFFSPIQWDELVAKKIQPPYVPVLSGPGDLTNIDPRFTELPVPHSLG---ACEDHGANFPGFTFINENILSLTRGH--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12688-1", "uniprot_id": "YPK1_YEAST", "id": "P12688-1", "name": "Serine/threonine-protein kinase YPK1", "aln": "MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHDASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETANIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQDEKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLAR-VDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYN-GADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. . : **. *****.*.:***: . :: **:*.::* ::...* : :.*: ** : : **:* *::***: ::**:** : *****:***:* * *****:**: .*:. **.:.::************ **: * ****** : .* ************:: * .:**** **.:*:*** ****:: : :* :*: :** : . * :* ** :: .*** . . :::.* **. :.* * * **: * : .. * ::* ** *: . . . :. : ", "identical_positions": 125, "similar_positions": 92, "identity": "18.25%" }, { "cls_id": "homologset.agr.SGD:S000001610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0F9-1", "uniprot_id": "PGM1_MOUSE", "id": "Q9D0F9-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQSNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------SVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38652-1", "uniprot_id": "PGM1_RAT", "id": "P38652-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQGNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIASYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------RVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDAAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36871-1", "uniprot_id": "PGM1_HUMAN", "id": "P36871-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYQDQKP-GTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------SVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZF8-1", "uniprot_id": "PGM5_MOUSE", "id": "Q8BZF8-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRNIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSTALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKYGRHYYCRFDYEGLEPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVR9-1", "uniprot_id": "PGM5_RAT", "id": "D3ZVR9-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYTICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKYGRHYYCRVLYEAKSPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15124-1", "uniprot_id": "PGM5_HUMAN", "id": "Q15124-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQ---LKIRIDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0B3-1", "uniprot_id": "PGM5_DANRE", "id": "B0R0B3-1", "name": "Phosphoglucomutase-like protein 5", "aln": "METNPIPILTIQTTPFDDQRP-GTNGLRKKTAVFESNNNYLQNYIQSVLSSIDLRDRQGCTMVVGSDGRYFSRAATEVIVQMAAANGIGRLVIGHNGILSTPAVSCIIR--KIKAIGG-IILTASHSPGGPGGDFGIKFNVANGGPSPDTVIERIHQVSRTLEEYAICPDL-HIDLSRLGRQDFDLENKFKPFRVEIVDSVEIYFNLLRGIFDFSGIKSLLTGPNQ---LKIRIDAMNGVMGPYVRRILCDELGAPANSAVN-CVPLEDFGGQHPNPNPAFAGPLVDSMKGGEFGFGAAFDADGDRYMIMGENGFFVSPSDSLAVMAANLSCIPYFSQRGIRGFARSMPTSTAIDRVAKAMKVALYETPTGWRFFGNLLDSGRCSFCGEESFGTGSDHIRDKDGLWSVLVWLSIMAVRKQ-------GVEEIVRDHWAKLGRNYFCRFDYEGVDGKAAFYLMRDLEAVITDKAFTTQKFSVGNTVYSVEKADNFEYIDPVDGSVSRKQGLRIIFTDSSRIIFRLSGSGSGTGATVRIYAESYERDPERHNRETQVVLGPLIAIALKISNIHERTGRRGPNIIT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUY9-1", "uniprot_id": "PGM_DROME", "id": "Q9VUY9-1", "name": "Phosphoglucomutase 1", "aln": "---MSLTVEIVATKPYEGQKP-GTSGLRKKVKVFT-QPNYTENFVQAILEANG-AALAGSTLVVGGDGRFYCKEAAELIVRLSAANGVSKLLVGQNGILSTPAVSSLIR--HNKALGG-IVLTASHNPGGPENDFGIKFNCENGGPAPDAFTNHIYKITTEIKEYKLVRNL-QIDISKVGVTSFDIAG--KPFTVEVIDSVANYVRHMEEIFDFAKLKDFVSGKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVH-TTPLPDFGGLHPDPNLTYAKDLVDTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSDSLAVIAHYLEAIPYFQKNGVQGFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLCLCGEESFGTGSNHIREKDGIWAVLAWISVMQHTGK-------GIEDILKQHWSVYGRNYFTRYDYEECASDPCNEMVATMEKTITAPEFVGKSYSSGGKTYKVKEADNFSYTDPVDKSVATKQGLRIVFEDGSRIVVRLSGT-GSSGATVRLYIDSYEKE--NVLGQASVMLKPLIDIALEISQLPKFTGRNAPTVIT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33401-1", "uniprot_id": "PGM1_YEAST", "id": "P33401-1", "name": "Phosphoglucomutase 1", "aln": "---MSLLIDSVPTVAYKDQKP-GTSGLRKKTKVFMDEPHYTENFIQATMQSIP-NGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHIIRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHYKIIKNFPKLNLNKLGKN-----QKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDKGWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLVDRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYAPEIPYFAKQGIYGLARSFPTSSAIDRVAAKKGLRCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHIREKDGLWAIIAWLNILAIYHRRNPEKEASIKTIQDEFWNEYGRTFFTRYDYEHIECEQAEKVVALLSEFVSRPNVCGSHFP-ADESLTVIDCGDFSYRD-LDGSISENQGLFVKFSNGTKFVLRLSGT-GSSGATIRLYVEKYTDKKENYGQTADVFLKPVINSIVKFLRFKEILGTDEPTVRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * .: .*:* * .***: . :* . :* *::*: :.: *:***.***:: : :. :.****: :*::*:.*:*****.* :** . *. ** *:***** **** .::*:*:* ****:*: . : * : : : .* : :: ::::. :* *: *:::*.. * :. **** :* ::: *: .*:::*: *.* : :: :.:* . ...:: ** **** **:** ::* *:: : . :*** *.**** ** * **.*.**:*::* **** : *: *:.**:**: *:* *. :*.*:**::* *:*: : :**********:*:*:***:*:::.*:.:: : :: * :.* ** :: * ** . :: :. : . . :. . .: . ..*.* * :* ::: :*** : * :.::::.***.: .. **:*:* :.* . ....* *:* ::. .: : * *.: *", "identical_positions": 168, "similar_positions": 195, "identity": "28.82%" }, { "cls_id": "homologset.agr.SGD:S000001612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q634-1", "uniprot_id": "MYO1E_MOUSE", "id": "E9Q634-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGAYRYHWQSHNVKHSGVDDMVLLS-KITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVS--GGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGIT-SMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNS------------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPV----WRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVAR------------------KKYVQMREEASDLLLNKK----ERRRNSIN--RNFIGDYIGMEER----PELQQFVGKREKIDFADT----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIF---ILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLP-----LKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAILKPSNKVLQVSIGPGLPKNSR-----PTRRNTVTSRGYPGGTKN-NYPMR--------AAPAPP-GCHQNGVIRNQFV--PPPHAFGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDA-QDTDELSFNANDIIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63356-1", "uniprot_id": "MYO1E_RAT", "id": "Q63356-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGAYRYHWQSHNVKHSGVDDMVLLS-KITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVS--GGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGIT-SMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNINFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNS------------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPV----WRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVAR------------------KKYVQMREDASDLLLNKK----ERRRNSIN--RNFIGDYIGMEEH----PELQQFVGKREKIDFADI----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEVERILSVSLSTMQDDIF---ILHEQEYDSLLESVFKTEFLSLLTKRYEEKTQKQLP-----LKFSNTLELKLKKENWGPWSAGGSRQVQFYQGFGDLAILKPSNKVLQVSIGPGLPKNAR-----PTRRNTVSSRGYSGGTNN-NYPMR--------AAPAPP-GCHRNGLTRNQFV--HPPRASGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDA-QDTDELSFNANDVIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12965-1", "uniprot_id": "MYO1E_HUMAN", "id": "Q12965-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGVYQYHWQSHNVKHSGVDDMVLLS-KITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS--GGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGIT-SMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNS------------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPS----WQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVAR------------------KKYVQMREEASDLLLNKK----ERRRNSIN--RNFIGDYIGMEEH----PELQQFVGKREKIDFADT----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIF---ILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLP-----LKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPGLPKNSR-----PTRRNTTQNTGYSSGTQNANYPVR--------AAPPPP-GYHQNGVIRNQYV--PYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDA-QDTDELSFNANDIIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O00160-1", "uniprot_id": "MYO1F_HUMAN", "id": "O00160-1", "name": "Unconventional myosin-If", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLP-QITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS--GGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLM-TPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCE-DGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGG-RSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNS------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKK--GRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAV------------------RKYEEMREEASNILLNKK----ERRRNSIN--RNFVGDYLGLEER----PELRQFLGKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFF---ILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLP-----LTFSDTLQFRVKKEGWG---GGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSK-----PTRKGMAKGK----PRRSSQAPTR--------AAPAPPRGMDRNGVPPSARG-GPLPLEIMSGGGTHRPPRGPPSTSLG---ASRRPRARPPSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVG-QDVDELSFNVNEVIEILMEDPSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7X9-1", "uniprot_id": "D4A7X9_RAT", "id": "D4A7X9-1", "name": "", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLP-QITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS--GGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGLM-TPDYYYYLNQSDTYKVEGTDDRSDFNETLNAMQVIGIPTSVQQLVLQLVAGILHLGNISFCE-EGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSKWGG-RSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLNPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNS------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQAFLRMLFPEKLDVDKK--GRPSTAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHIAV------------------RKYEEMREEASNILLNKK----ERRRNSIN--RNFVGDYLGLEER----PELRQFLAKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGLVREVLKKKLEIQALRGVSLSTRQDDFF---ILQEEAADSFLESIFKTEFVSLLCKRFEEAARRPLP-----LTFSDMLQFRVKKEGWG---GGSTRNVTFSRGTGDLAVLKAGSRALTISIGDGLPKSTK-----PTRKGLAQGR----PRRSAQAPTR--------AAPGPPRGLNRNGVPPSSQV-RSLPMEITSGRSSQRPPRGPPSSTLG---ASRRPRARPPSEHNTEFLNVPDQGVAGMQRKRSIGQRPVPGVGRPKPQPRTHGPRCRALYQYIG-QDVDELSFNVNEVIEILMEDSSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70248-1", "uniprot_id": "MYO1F_MOUSE", "id": "P70248-1", "name": "Unconventional myosin-If", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLS-QITEDAIVRNLHKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAVQYEEPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS--GGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGIM-SQDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVMGFRQACQQLVLQLVAGILHLGNISFCE-EGNYARVESVDSLAFPAYLLGIDSGRLQEKLTSRKMDSKWGG-RSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNS------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKK--GRPSTAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAV------------------RKYEEMREEASNILLNKK----ERRRNSIN--RNFVGNYLGLEER----PELRQFLAKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGTEKVKRGPEKGLVREVLKKKLDIQALRGVSLSTRQDDFF---ILQEEAADTFLESIFKTEFVSLLCKRFEEAARRPLP-----LTFQDILQFRVKKKGWG---GGGTRNVTFSAGQVNLAVLKAGGKTLTISLGDGLPKNSK-----PTRKGLAQGK----PRRSAQAPTR--------AVPWASQGLNRNGATLFPRGEGPYTLEIYIWP--QEFPEASTAIHLQPQDASRRPRARPPSEHSTEFLNVPDQGVAGMQRKRSIGQRPVP-ASRPKPQPRTHGPRCRALYQYIG-QDVDELSFNVNEVIEILIEDSSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36006-1", "uniprot_id": "MYO3_YEAST", "id": "P36006-1", "name": "Myosin-3", "aln": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLS-KISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASN-SHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQ-MPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVN-----VSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAK-NPPGILAAMNDSIATAHADSNAADQAFAQRLNLFN-SNPYFEL------------RANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSK--RRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKK----ERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIG-----QTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPS-SKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q23978-1", "uniprot_id": "MY31D_DROME", "id": "Q23978-1", "name": "Unconventional myosin ID", "aln": "-----------------------MAMQR------EAGVQDFVLLD-QVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQ---GSMDILTEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQT-IEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAA-----GGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQP--HKGIIAIMDEACLSVGKV---TDDTLLGAMDKNLSKHPHYTSRQLKPTD-KELKHREDFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFR---AGSDRDGVRVLIEEKKFAQD-VKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVR------------------RNFKKMKAAITIVRAYK----------------------------------------------------------AYKLRSYVQELANR--------------------LRKAKQMRDYGKSIQWPQPP-----------LAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLR-----LQIIAATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKNIRNHPADGET----------FQQVLFSSFVKKFN-HFNKQANR--------AFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIGEVVGIVCKKYHDLTGTELRVNVTTNISCRLDGKARIITVEAASNVEVPNFRPKEGNIIFEVPAAYCV-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23979-1", "uniprot_id": "MY61F_DROME", "id": "Q23979-1", "name": "Unconventional myosin IC", "aln": "----------------MASFNSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACS--GNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTE-VEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDA-----RGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLN--ISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEK--HKGIISILDEECLRPGEP---TDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPE---KELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKG--PGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQR------------------RKYLKLRAQVIIMQSYCRRKLAQQAAK-------------------------------------------KRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAP-----------GHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFE-----LKVLAEKVFKGKKNNYASS---VSTWFQEDR------IPKEHIQRVNDFVASTFG----------SEQLKYQSFCTKFDRHGYKSRDR--------FILLSNKAIYVLDGKTYKQKHRLPLDKI----DFTLTNHNDDLMVIRIP----LDLKKDKGDLILIIPRIIEFSTYIIDTVGTAS-IVSIVDRNSLEHNVVKGKGGVIDIQTG--AEPGVVRDKGHLVIIGTQ------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:.*:.** : . : **:**: :. *:**** * :*:**:::: : : *:. * .**::*:::. : : .. *::******:*** *:* :: ::: : : :*: :: :*.:**:** *** **:****.***::*:*. * .* * *:****.*** : .**.** :**: **. : : * * : .: . *: .:.: : :*.:* :**: * . : . . * ** : * *. * : : .. * * :*****.:: .:* :::. :* . : : :*:*********: *.***:***: ******:**:*.** **: * :* *.* ::**:**::*:*:* **:: ::: :*.:: : : :: * : ****.* *.:.*: ::*.* * *: . : .: : :*: : ** ** : . :*: * * *:* ****: : . ::: * ***.**** **:*:****:.:*: : *: *: :: * .* ::. . : * :.:*:: *.:** *. :. . :* : : .:: ::: : : : : : . . . . :. . . : . : : .: . : . . : . . . . : :: ", "identical_positions": 193, "similar_positions": 239, "identity": "14.78%" }, { "cls_id": "homologset.agr.SGD:S000001617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01992-1", "uniprot_id": "MIPEP_RAT", "id": "Q01992-1", "name": "Mitochondrial intermediate peptidase", "aln": "----MLLAAGTRYAYRLCGRRAAAALQGRAGRS----------CARSVSTSWSPVGAAFNVKPQGHLWDLLGERRGLFGVPELSTPEGFQVAQEEALRKTEWLVERACSTPPGP---QTVLIFDELSDCLCRVADLADFVKIGHPEQAFREAAQEACRSIGTMVEKLNTNVELYQSLQKLLDDKKLMDSLDAETRRVAELFMFDFEISGIHLDEEKRRRAVDLNVKILDLSSAFLMGTNFPI----KIQKHLLPEHIQHHFARDGRHLVIDG--------------LHAEASDDLVREAAYKIFLYPNADQLKCLEELLSSRDLLANLVGYLPFPT-GPPGTIAQTPETVMQFLEKLSEKLCERTRKDFEMMQGMKTKLN-PQNSE--------LMPWDPPYYSGVIRAERYNIEP--SLYCPFLSLGACMEGLNVLFNRLLGVTLYAEQPFKGEVWCIDVRKLAVVHESEGLLGYIYCDFFQRANKPQQDCHFTIRG----------------GRLKEDGSYQLPVVVLMLNLP---HASRDFPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFSNDYRVVSQFAKHYQTGQPLPKAMVSRLCESKKVCAAAEMQLQVFYAALDQIYHGQHPLK-KSTTDILMETQEQFYGLPYVPD--TAWQLRFSHLVGYGAKYYSYLMSRAVASMVWKECFLQDPFNRAAGERYRREMLAHGGGKEPMLMIQGMLQKCPSIDDFVDALVSDLNLD---FETFFMDSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H611-1", "uniprot_id": "MIPEP_MOUSE", "id": "A6H611-1", "name": "Mitochondrial intermediate peptidase", "aln": "----MLLAAGARYARRLCGRGAAAALQGRTGRS----------CARDVSTSWSPVGAAFNVKPQSHLWNLLGERRGLFGVPELSTPEGFQVAQEEALKKTEWLVERACSTPPGP---QTVLIFDELSDCLCRVADLADFVKIGHPDPAFREAAQEACRSIGTMVEKLNTNVELYQSLQRLLGDKKLMESLDAETRRVAELFMFDFEISGIHLDEEKRRRAVDLNVKILDLSNAFLMRTNFPN----KIRKSLLPEHIQHHFARDGSHLIIDG--------------LHAEASDDLVREAAYKIFLYPNADQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAQTPETVMQFLEKLSEKLSERTRKDFKMMQGMKTKLN-PQNSK--------LMPWDPPYYSGVIRAERYNIEP--SLYCPFLSLGACMEGLNVLFNKLLGITLYAEQTFKGEVWCNDIRKLAVVHESEGLLGYIYCDFFQRANKPQQDCHFTIRG----------------GRLKEDGSYQLPVVVLMLNLP---HASRDFPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFSNDYRVVSQFAKHYQTGQPLPKAMVSRLCESKKVCTAAEMQLQVFYAALDQIYHGQHPLK-KSTTDILMETQEQFYGLPYVPD--TAWQLRFSHLVGYGAKYYSYLMSRAVASMIWKECFLQDPFNRAAGERYRREMLAHGGGKEPMLMIQGMLQKCPSIDDFVDALVSDMNLD---FETFFLDSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99797-1", "uniprot_id": "MIPEP_HUMAN", "id": "Q99797-1", "name": "Mitochondrial intermediate peptidase", "aln": "-----MLCVGRLGG---LGARAAALPPRRAGRGSLEAG----IRARRVSTSWSPVGAAFNVKPQGSRLDLFGERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGP---QTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPN----KIEKHLLPEHIRRNFTSAGDHIIIDG--------------LHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLN-PQNSE--------VMPWDPPYYSGVIRAERYNIEP--SLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKLAVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRG----------------GRLKEDGDYQLPVVVLMLNLP---RSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLR-NSTTDILKETQEKFYGLPYVPN--TAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAGERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLD---FETFLMDSE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B497-1", "uniprot_id": "A0A8M2B497_DANRE", "id": "A0A8M2B497-1", "name": "Mitochondrial intermediate peptidase", "aln": "-----MSVTRVRPLVCLFGRGAAVR------------------LCRTVST-WSPVGAAFNAKVQR-RLELFQQNVGLFGVPELSSVDGFEVVQDRALQETEQLVEEACRCPAGV---QTVQIFDKLSDSLCRVADMADFIKVAHPDPSYREAAEKTCINIGTMVERLNTNVELCKSLKDLLDNKEVMSKLDPETRRVAELFMFDFEISGIHLDTKKRKEAVNLNVKLLDLSNQFLMSCHMPN----RIEKKALPEHIHQHFTKDGKYIQIGG--------------LHADAPDDLVREVAYKVFLYPNANVMHILEELLACRDKLARLVGYESYAHRALKGTMAKSPEAVMNFLQQITDKLADRTEKDFKMMRDMKTKLN-PQNSE--------LMPWDHPYFSGVTRAERFNIEP--SLYSPYFSLGACMEGLNGVFTQLYGVSLLAEQPSVGEVWSEDVRKLAVVHETEGLLGYIYCDFFYRQDKPHQDCHFTIRG----------------GRRLDDGQYQLPMVVLMLNLP---HPTRASPTLLSPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCATDFAEVPSILMEYFATDYRVISQFARHYQTGQPLPQSMVARLCESKKVCGAADTQLQVFYSVLDQVYHGK-PQN-RSTTDIMIDLQKKYYGLPYVTN--TAWQLRFSHLIGYGAKYYSYLMSRAVASMVWKQCFYKDPLNRETGEHYRREMLAHGGGKEPMLMVEGMLQKRPSMEDFVKALVSDLDPD---FETFIMDSEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6H6-1", "uniprot_id": "A1Z6H6_DROME", "id": "A1Z6H6-1", "name": "Peptidase M3A/M3B catalytic domain-containing protein", "aln": "-----MLEFGRTLLRWRTRH-----------------------CSRRVST-WTPLATAFNAPPAR-RINFTHDDVGLFGMPELRSFEGFYLLRDNVESRTQELISEATSDQRRR---KMVDIFDELSDSLCKVADLAEFVRIAHPQSRYTQAAEQACISICGMVESLNTHKPIYKALSHVVDHGDKLPTSEVD-RHVSRLFLFDFEQCGIHLPEEERMRVVRLNDYILQLGQKFMSGAVQPS----VLPRSQVPESFRNYFPTSGENVIITG--------------LCTNAENVQMREAAYRLYLQPSKSQEDLLRDLLLCRHELARSCGFDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKRREGGKADAR--------AEVWDTPYYTNQLRRQLFEEHA--NEFLPYFSLGGCMEGLDNLLHALYGIRLQNTDLKPGEAWHNDIYKLAVVHEREGLLGYIYCDFYERVGKPNQDCHFTIQG----------------GKRMPDGSYQLPVVVVMLGLA---QPRWSGPTLLSPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCSTDFAEVPSVLMEYFAGDPRVLRTFARHFQTHEPISEDMLRRLCASKNLFAASETQLQVFYSALDQEYHGASARHGQSSTDTLRSVQDHYYGLPYVDN--TAWQLRFSHLVGYGAKYYAYLVSKTIASWIWQTYFEANPFNRQAGEKYRAEILAHGGAVPSRKLVANFLQREMTPSVLADSLITEIDTDESKIKDLMITRT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35999-1", "uniprot_id": "PMIP_YEAST", "id": "P35999-1", "name": "Mitochondrial intermediate peptidase", "aln": "MLRTIILKAGSNASIPSPSRQNKLLRFFATAGAVSRTSPGSIKKIFDDNSYWRNINGQDANNSKISQYLFKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQELLDKMRNDFSESGKLTYIMNLDRLSDTLCRVIDLCEFIRSTHPDDAFVRAAQDCHEQMFEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEELKVGKILLDDFEKSGIYMNPDVREKFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLLKQLNKDVKGQNYKVPTFGYAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIKLRAILANLMHKTSYAEYQLEGKMAKNPKDVQDFILTLMNNTIEKTANELKFIAELKAKDLKKPLTTNTDEILKLVRPWDRDYYTGKYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIYGIRLEPAITDEGETWSPDVRRLNVISEEEGIIGIIYCDLFERNGKTSNPAHFTVCCSRQIYPSETDFSTIQVGENPDGTYFQLPVISLVCNFSPILIASKKSLCFLQLSEVETLFHEMGHAMHSMLGRTHMQNISGTRCATDFVELPSILMEHFAKDIRILTKIGKHYGTGETIQADMLQRFMKSTNFLQNCETYSQAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVLVDDQSNWCGRFGHLFGYGATYYSYLFDRTIASKIWYALFEDDPYSRKNGDKFKKHLLKWGGLKDPWKCIADVLECPMLEKGGSDAMEFIAQSHKS-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: * : : : *** * * : :*: : .:: *:.. : :*.*** **:* *:.:*:: **: : .**:. .: ::: ***. : : *. :: . . . . : :*..::: *** .**:: . * . : *. : :.. *: * : : : * : * * .. : :*: : . . * .*: * **. .:. *. :.*: * :*: : :: :: :: :: :* : : ** *::. . . . :::** ::**. :: : *: * **.* *: :* *: * **::* ****:: * .*. : .***: *. . :***:: :: .:. . :* . ::.*************.**. *:::****.***.*:**:***:*: * *:: :.:*: * :.: *: *: *.:. .: *. : *** :*. .. * : . * * : : : * **.**.**** **:**..:::** :* * :* .* *:::: .:* ** . : ..*: . .:: : . ", "identical_positions": 151, "similar_positions": 211, "identity": "19.28%" }, { "cls_id": "homologset.agr.SGD:S000001618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63010-1", "uniprot_id": "AP2B1_HUMAN", "id": "P63010-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK--KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62944-1", "uniprot_id": "AP2B1_RAT", "id": "P62944-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK--KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBG3-1", "uniprot_id": "AP2B1_MOUSE", "id": "Q9DBG3-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK--KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTTTNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35643-1", "uniprot_id": "AP1B1_MOUSE", "id": "O35643-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK--KGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYATLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPNAFVEGGRGVVHKSLPPRTASSESTESPETAPAGAPAGDQPDVIPAQGDLLGDLLNLDLGPPVSGPPLAASSVQMGAVDLLGGGLDSLIGD----------------------------SNFGAPSASVAAAPAPARLGAPIS------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQAGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHVPLSPNQTVEISLPLNTVGSVLKMEPLNNLQVAVKNNIDVFYFSTLYPLHVLFVEDGKMDRQMFLATWKDIANENEAQFQIRDCPLNTEAASNKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSFT---LSLKCRAPEVSQHVYQAYETILKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52303-1", "uniprot_id": "AP1B1_RAT", "id": "P52303-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK--KGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANRVAALSEIAESHPSSN-LLDLKAQSINKLLTALNECTEWAQIFILDCLGNYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYATLLKKLAPPLVTLLSAEPEPQYVPLRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLDGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPNAFVEGGRGVVHKSLPPRTASSESTESPEAAPAGAPASDQPDVIPAQGDLLGDLLNLDLGPPVSGPPLAASSVQMGAVDLLGGGLDSLMGDEP---------------------EGIGDSNFGAPPASVAAA-APARLGAPVS------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLNTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHVLFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNTEAASSKLQSSNIFTVAKRTVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSFT---LSLKCRAPEVSQHDIQAYETILKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10567-1", "uniprot_id": "AP1B1_HUMAN", "id": "Q10567-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK--KGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVIPAQGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEP---------------------EGIGGTNFVAPPT----AAVPANLGAPIG------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLSTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHILFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNAEAASSKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSCTDLELSLKCRAPEVSQHVYQAYETILKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCE3-1", "uniprot_id": "A0A8M2BCE3_DANRE", "id": "A0A8M2BCE3-1", "name": "AP complex subunit beta", "aln": "MEWASQLCENRGLGSKMTDSKYFTTTK--KGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPNSN-LLDLNPQTINKLLTALNECTEWGQIFILDCLANYTPRDDRESQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLPKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEPTLLDELICHIGTLASVYHKPPSAFVEGSRGVQHKRLPARAGSGESAESPEVGQSGTSEAP-PAVIPSQGDLLGDLLNLDLAPATTTVPSVQPSMQMGAMDLLGGGLDSLMGDESDTPGVSHRTEMQSPQPSSDYSERELGGDIGGSPSMGAALGAPAAMPAALSNAPAVGGGLGDLFDLGGGVGMPTGFYVAPKTLFLPAMKAKGLEISGTFARRGGIIQMDLSLTNKAMSVMTDFAIQFNRNSFGLAPAGPLQVLTPLTPNQTIDVSLPLGTTGPVMKMEPLNNLQVAVKNNIDVFYFSCQYPLSLLFVEDGKMERQVFLATWKDIPNDNEAQFQIKDVHLNSDAASNKLQGSNIFTIAKRTVDAQDMLYQSIKLTNGIWVLAEMRVQTGNPNYT---LSIKCRAPEVSQFVYQCYELVLKN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24253-1", "uniprot_id": "Q24253_DROME", "id": "Q24253-1", "name": "AP complex subunit beta", "aln": "----------------MTDSKYFTTTK--KGEIFELKSELNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLYDISATMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEINEASQSGQPLVEMNSVTINKLLTALNECTEWGQVFILDSLANYSPKDEREAQSICERITPRLAHANAAVVLSAVKVLMKLLEMLSSDSDFCATLTKKLAPPLVTLLSSEPEVQYVALRNINLIVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ---VLSELKEYATEVDVDFVRKAVRAIGRCAIKVEPS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESIISTLCENLDTLDEPEARASMVWIIGEYAERIDNADELLDSFLEGFQDENAQVQLQLLTAVVKLFLKRPSDTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLST--DPAAAKEVVLADKPLISEETDLLEPTLLDELICHISSLASVYHKPPTAFVEGRGAGVRKSLPNRAAGSAAGAEQAENAAGS----EAMVIPNQESLIGDLLSMDINAPAMPS----APAATSNVDLLGGGLDILLGGP-------------------------------------PAEAAPGGATSLLG----------DIFGLGG--ATLSVGVQIPKVTWLPAEKGKGLEIQGTFSRRNGEVFMDMTLTNKAMQPMTNFAIQLNKNSFGLVPASPMQA-APLPPNQSIEVSMALGTNGPIQRMEPLNNLQVAVKNNIDIFYFACLVHGNVLFAEDGQLDKRVFLNTWKEIPAANELQYTLSGVIGTTDGIASKMTTNNIFTIAKRNVEGQDMLYQSLKLTNNIWVLLELKLQPGNPEAT---LSLKSRSVEVANIIFAAYEAIIRSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36000-1", "uniprot_id": "AP1B1_YEAST", "id": "P36000-1", "name": "AP-1 complex subunit beta-1", "aln": "-----MPPLDKRIKKFLKDSIRIAPKISGKGELSELRTGLVSQYPQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHPELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAKLFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHVSQFLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKVIVRNLPQIEYSS--NSLIMKRLSSAFVSLMSTPPEMQYVALKNIRIILEKYPELLTKELRIFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCTLLLTELKEYAMEYEPEFVSRAIQALSQLGIKYAQESFVSKVLDILLELLE-RQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAVFNTWSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLESKINIFIENFVQEEALTQMSLLMTIVRLHATLTG---SMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNNESLVNDLCQNKLPMISNTLEKFSPEVLEKLLMELGTISSIYFKPDSNRRKGKKYVQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------IVKGKHIEELESMAKN-----------EISSKANDDVLLDFDERDD--------------VTNTNAGMLNTLTTLGDLDDLFDFGPSEDATQIN----------------------------------TNDTKAVQGLKELKLGGDSNGISSGGKNNPDVSGGNIVSQDLLDLF---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 230, "similar_positions": 282, "identity": "22.7%" }, { "cls_id": "homologset.agr.SGD:S000001620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPZ8-1", "uniprot_id": "COXM1_MOUSE", "id": "Q9CPZ8-1", "name": "COX assembly mitochondrial protein homolog", "aln": "MAL---------------DPAEQHLRHVEKDVLIPKIIREKAR-------ERCSEQVEDFTRCCKDSGILMVLKCRKENSALKDCLTAYYNDPAFYEECKLEYLKEREEFRKTGVPTKKRLQKLPTNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7K0-1", "uniprot_id": "COXM1_HUMAN", "id": "Q7Z7K0-1", "name": "COX assembly mitochondrial protein homolog", "aln": "MAL---------------DPADQHLRHVEKDVLIPKIMREKAK-------ERCSEQVQDFTKCCKNSGVLMVVKCRKENSALKECLTAYYNDPAFYEECKMEYLKEREEFRKTGIPTKKRLQKLPTSM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJJ1-1", "uniprot_id": "Q9VJJ1_DROME", "id": "Q9VJJ1-1", "name": "COX assembly mitochondrial protein", "aln": "MSLEQQPAVDPHNPHGLGDPNDTRLRKVEREVLIPKIMRDRAKT------EFCSKEVADFQECCKASSILMVATCRKQNSALKECLTQWYQNEAFKEECKQIYLQERADYRSTGIPKKHRLEKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36064-1", "uniprot_id": "COXM1_YEAST", "id": "P36064-1", "name": "COX assembly mitochondrial protein", "aln": "MEQNKDP-----------QMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCANFVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKIN-KLEKLCQKQSSTK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : :: ** *: :: : : *:: * : *.* ..: :. .* *:.. :*.** : : : : : : *: : : : *: * ", "identical_positions": 16, "similar_positions": 36, "identity": "12.5%" }, { "cls_id": "homologset.agr.SGD:S000001622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14AX6-1", "uniprot_id": "CDK12_MOUSE", "id": "Q14AX6-1", "name": "Cyclin-dependent kinase 12", "aln": "---------------------MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDVGLVTPEAAS-----LGTIIKPLVEYDDISSDSD---------TFSDDTAFKSDRRENEERRGTDRSDRLHRHRHHQHRRSRDLLKTKQTEKEKNQEVS--------------KSGSMKDRVSGSSKRSVEGSDD---YGKAQLSKSGSKESRSSKMHKEKTRKERELKSG-YKDRSKSHRKRETPKSYKTVASPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISP-PYKEPS-AYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRS-PSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKSSPIILPKKEK--LEVKESGLESKKLPRSIKSEKSTPDTELVTVAHSNPEVKHC----LDTGKVRLDENLQKHPAKDLKAQGTKDVKPVAPKEVIVTSKETETSEKETLPPLPTITSPPP-LPATTPPPQTPPLPPLPPLPAIPLQPPLPPPQPPFSQVPVSSTSILPSSPHPRTSTLSSQTNSQPPVQVSMKTQVSITAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPAKKEKEQR-------TRHLLTDLPLPPELP-----GGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYG-------ERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGIVIEDPPPSKASRKETTSGTTAEPVKNNSPAPPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVPVVLPPAEQTTPEASNTPADMQNVLAVLLSQLMKTQEPAGN---LEENTNDKNSGPQGPRRTPTMPQEEAAACP-------------------PHILPPEKRPPEPPGPPPPPPPPPLVEGD------LSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRSHPNRTYG----------NTDGPETGFSSADTDER--------------SSGPALTESLVQTPVKNRTFSGSVSHLGESNSYQGTGSVQFPGDQDLRFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELGPGTTGANSSGTTLQWGGPAQS--YGKPYRGAARVLPRGGRGRGVPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MJK5-1", "uniprot_id": "CDK12_RAT", "id": "Q3MJK5-1", "name": "Cyclin-dependent kinase 12", "aln": "---------------------MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAAS-----LGTIIKPLVEYDDISSDSD---------TFSDDMAFKSDRRENDERRGTDRSDRLHRHRHHQHRRSRDLLKTKQTEKEKNQEVS--------------KSGSMKDRLSGSSKRSVEGNDD---YGKAQLSKSSSKESRSSKMHKEKTRKERELKSG-HKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISP-PYKEPS-AYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRS-PSPYGRRRSSSPFLSKRSLSRSPISSRKSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKLDGKESKGSPIILPKKEK--FEVKESGLESKKLPRGIKSEKSTPDTELVNVAHSNTEVKNC----LDTGKVKLDENLQKHPVKDLKAQGTKDTKPVALKEVIVTSKETETSEKEALPPLPTITSPPP-LPSTTPPPQTPPLPPLPPLPAVPLQPPLPPPQPPFSQVPVSNTSTLPSSPHPRTSTLSSQTNSQPLVQVSMKTQLSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKEMLPSKPAKKEKEQR-------TRHLLTDLPLPPELP-----GGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYG-------ERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGIVIEEQPPSKASRKETTSGTAAEPVKNSSPAPPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVSVVLPPAEQTTPEASNTPADMQNMLAVLLSQLMKTQEPAGN---LEENTSDKNSGPQGPRRTPTMPQEEAAACP-------------------PHILPPEKRPPEPPGPPPPPPPPPLVEGD------LSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRSHPNRTYG----------NTDGPETGFSATDTDER--------------SSGPALTESLVQTLVKNRTFSGSVSHLGESNSYQGTGSVQFPGDQDLRFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELGPGTTGANSSGTTLQWGGPAQS--FGKPYRGAARVPPRGGRGRGVPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYV4-1", "uniprot_id": "CDK12_HUMAN", "id": "Q9NYV4-1", "name": "Cyclin-dependent kinase 12", "aln": "---------------------MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAAS-----LGTVIKPLVEYDDISSDSD---------TFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSS-------------KSGSMKDRISGSSKRSNEETDD---YGKAQVAKSSSKESRSSKLHKEKTRKERELKSG-HKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSP-PYKEPS-AYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRS-PSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNS----SDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQR-------TRHLLTDLPLPPELP-----GGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYG-------ERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGS---LEENNSDKNSGPQGPRRTPTMPQEEAAACP-------------------PHILPPEKRPPEPPGPPPPPPPPPLVEGD------LSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYG----------NTDGPETGFSAIDTDER--------------NSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69ZA1-1", "uniprot_id": "CDK13_MOUSE", "id": "Q69ZA1-1", "name": "Cyclin-dependent kinase 13", "aln": "---------------------MPSSS--DTALGGGGGLSWAEKKLE-----ERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGAAAAAAAAAAASSS---------CFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGSPASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGS--EASKARSRHGHSGEERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAYREDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYS--RRLPRSPSP-----YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSP----VLRRSAKSRSRSPYSSRHSRSRSRHR---LSRSRS-----RHSSIS----PSTLTLKSSLAAELNKNKKARAAEAARA----AEAAKAAEAAKAAEAAAKAAKAS---NASTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSP---SSGGTVKSDKAKTKPPLQVTKVDNNLTVEKATKK-TVVGKESKPAATKEEPVSTKEKSKPLTPSTGAKEKEQH------VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKK-------LRCLLADLPLPPELP-----GGD-DLSKSPE-EKKTAAQLHSKRRPKICGPRYG-------EIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKK--QYRRKLREEFVFIP--AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMG-MTDDLSTIKAPRKDLSLGLDDSRTNTPQGVLP-PAQLKSQSNSNVAPVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKIN--LPAGILATGEKQTDPSTPQQESSKSLGGVQPS--QTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDAMLEERENGSGHEAPLQLRPPLEPSTPGSGQDDLIQHQDRRILELTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGIDYPTGDTYVPSSDYKDNFG-SSFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQSLDNYSTASSHTGGPPQTSAFTESFASSVAGYG--DIYLNAGPMLFSGDKDHRFEYSHGPITVLTNSNDPSTGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M1X9-1", "uniprot_id": "F1M1X9_RAT", "id": "F1M1X9-1", "name": "", "aln": "---------------------MPSSS--DTALGGGGGLSWAEKKLE-----ERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGAAAAAAAAAAASSS---------CFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGSPASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGS--EASKARSRHGHSGEERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAYREDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYS--RRLPRSPSP-----YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSP----VLRRSAKSRSRSPYSSRHSRSRSRHR---LSRSRS-----RHSSIS----PSTLTLKSSLAAELNKNKKARAAEAARA----AEAAKAAEAAKAAEAAAKAAKAS---SVSTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSP---SSGGTVKSDKTKTKPPLQVTKVDNNLIVEKATKK-TVVGKESKPAATKEEPVSTKEKTKPLTPSVGAKEKEQH------VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKK-------LRCLLADLPLPPELP-----GGD-DLSKSPE-EKKTATQLHSKRRPKICGPRYG-------EIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKK--QYRRKLREEFVFIP--AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMG-MTDDLSTIKAPRKDLSLGLDDSRTSTPQGVLP-PAQLKSQNSSSGAPVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKIN--LPAGILATGEKQTDPSTPQQESSKSLGGVQPS--QSIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDAMLEERENGSGHDAPVQLRPPPEPSTPASGQDDLIQHQDRRILELTPEPERPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHGPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGIDYSTGDTYVPSSDYKDNFG-ASFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQSLDNYSTASSHTGGPPQTSAFTESFPSSVAGYG--DIYLNAGPMLFSGDKDHRFEYSHGPITVLTNSSDPSTGPESTHPLPAKIHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14004-1", "uniprot_id": "CDK13_HUMAN", "id": "Q14004-1", "name": "Cyclin-dependent kinase 13", "aln": "---------------------MPSSS--DTALGGGGGLSWAEKKLE-----ERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGTAAAAAAAAAASSS---------CFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGS--EASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRR-RSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYS--RRLPRSPSP-----YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSP----VLRRSGKSRSRSPYSSRHSRSRSRHR---LSRSRS-----RHSSIS----PSTLTLKSSLAAELNKNKKARAAEAARA----AEAAKAAEATKAAEAAAKAAKAS---NTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSP---SSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQH------VALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKK-------LRCLLADLPLPPELP-----GGD-DLSKSPE-EKKTATQLHSKRRPKICGPRYG-------ETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKK--QYRRKLREEFVFIP--AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMG-MTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLP-SSQLKSQGSSNVAPVKTGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKIN--LPAGILATGEKQTDPSTPQQESSKPLGGIQPSS-QTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDVLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGIDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSS-SAPPLERRSFIGNSDIQSLDNYSTASSHSGGPPQPSAFSESFPSSVAGYG--DIYLNAGPMLFSGDKDHRFEYSHGPIAVLANSSDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRGHISTSTGRGRGRGLPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03957-1", "uniprot_id": "CTK1_YEAST", "id": "Q03957-1", "name": "CTD kinase subunit alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYNNGNTYSKSYSRNNKRPLFGKRSPNP-----------QSLARPPPPKRIRTDSGYQSNMDNISSHRVNSNDQPGHTKSRGNNNLSRYNDTSFQTSSRYQGSR-------------------------YNNNNTSYENRPKSIKRDETKAE-------FLSHLPKGPKSVEKS-----RYNNSSNTSNDIKNGYHASKYYNHKGQEGRSVIA-------KKVPVSVLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQ---------KTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSR---ADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFKEE--PKPEPLVLDGLVSCHEYEVKLARKQKRPNILSTNTNNKGNGNSNNNNNNNNDDDDK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VP22-1", "uniprot_id": "CDK12_DROME", "id": "Q9VP22-1", "name": "Cyclin-dependent kinase 12", "aln": "MHASSAAATALVEYSDVSSEDFSDQEAGDLDADAGKGAGNIKKPKPAPDNQFSKGRLDAKPDKEGYDNYRSRRAEDSSDPVAAGSRQTSSSEATNPREEPSQASNTSKDELWGREIYMSSDSIDTDELEAEMKRQKRKKQKKEKHKHKSKKKSKKRKKKRAKSYSSIDSMSDNDINALLDRRYTPPTAPSKSNERTVSAAPSSFTPHNLKESSSPATPPPVRRPNTNSNYYGESSLETANSALGSNLQVTVTNKQSISNRLRSPPPSSRSSGNGPRFGNSPRTPPPSHYSSSGGGGVGSGSVVRDSRSSRYVNSPHKEDVSAHHRSSHDHGYQGRYSGAGSSSHDTRKVKRLSPELDRYNHQPSTPPHKRRKFSDGREVGLGNFEHSRHHSGKYERYSRDRYSRRSSRSPSVQHSRSRQSPSGGLSSGSNAFRHGGSHKHKYGTTVSSTPSHTTRTSKRASGTGTSGDRYSRSPRTSSRYMESSPPSPVGASGSHHYHHRRSPRMRQRTRGDSRRRSPSSASSESSASRSRSPTSRDLKHKREEYIKKISETSLFAELVKDRHKRQKALKEIIERQEENSNSNSNGALTINDNSSSVDGNTPNAADGRSAPGSGTPAAASTTSNGLQALGSKPDLDLNNIPMPNKQNDSVVSN-PASNADVPDSVAQLKQPLLVPPFSASKNNIKPKSLTSLPLPPGMNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVLNLPMPPVIPGSEELSGDDDVIDSPEDFDAPAVGTVHGHGGGPGTTRQRPVILNRRDSRNNVRDWGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKK--THRRRLREDFEFMP--APALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSKKRRRQMREQQESLPPTVIASTKYQQHGATMVGDA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : . . . .. . : . : . :.* . . : . * . . : . * : : . . :*... : * :******:****:: .* .:*****:**: *:******::****:*:.: * .: .::**:.:.: :.*::*** *:** *** . *.:...: :::**: *::* *.:::****:* ****::* *::*::****** .: ***:************** .* . :*:*.***:* *** * .:**.. *: *:* * :: *:* ** : .:* * : :: : ..: *.* : : .*:* :* * ** :* ::*:. :::. : . * .*** * *:* : . : ", "identical_positions": 129, "similar_positions": 138, "identity": "7.94%" }, { "cls_id": "homologset.agr.SGD:S000001623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9L7-1", "uniprot_id": "D4A9L7_RAT", "id": "D4A9L7-1", "name": "Lipase", "aln": "----------------MWWLLAT-CCMFLPG----------PIYGHMQE-------------------------------------------SITNPEANMNISEIISYWGYPYERHDVVTEDGYILGTYRIPHGKG-CSRKA---VPKAVVYLQ--HGLIASASNWICNLP-NNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPE-YWAFSLDEMAKYDLPATINLILE-----------------KSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQS----PMKKLTTLSRKAVKILFGDKMFSTHTWLEQFIATKVCN-RKLFRQLCSNFLFSLSGFDPQNLNMSRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMR--VPTAMWSGGRDVVADEKDTKN---LLP-KVAN--LIYYKEIPHYNHMDFYLGQDAPQEVYRDLITMMEESLQN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM14-1", "uniprot_id": "LIPK_MOUSE", "id": "Q8BM14-1", "name": "Lipase member K", "aln": "----------------MWWLLATTCCVLLSG----------PIDGYKQE-------------------------------------------SITNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKG-CSRKT---APKAVVYLQ--HGLIASANNWICNLP-NNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQ-YWAFSWDEMAKYDLPATVNLILE-----------------KSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRS----PMKKLTTLSRKAVKVLFGDKMFSTHTWFEQFIATKVCN-RKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMR--VPTAMWSGGQDVVADAKDTKN---LLP-KIAN--LIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMIEESLQN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VXJ0-1", "uniprot_id": "LIPK_HUMAN", "id": "Q5VXJ0-1", "name": "Lipase member K", "aln": "----------------MWQLLAAACWMLLLG----------SMYGYDKKG------------------------------------------NNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRG-CPGRT---APKPAVYLQ--HGLIASASNWICNLP-NNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPE-YWAFSLDEMAKYDLPATINFIIE-----------------KTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQS----PMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCN-RKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKME--VPTAIWNGGQDIVADPKDVEN---LLP-QIAN--LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04634-1", "uniprot_id": "LIPF_RAT", "id": "P04634-1", "name": "Gastric triacylglycerol lipase", "aln": "----------------MWLLL-ITSVISTFG----------GAHGLFGKL------------------------------------------GPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKN-NSENI---GKRPVVYLQ--HGLIASATNWIANLP-NNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVE-FWAFSFDEMAKYDLPATINFIVQ-----------------KTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQS----PLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCS-REVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMT--VPVAVWNGGNDILADPQDVAM---LLP-KLSN--LLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMAED--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPP7-1", "uniprot_id": "LIPF_MOUSE", "id": "Q9CPP7-1", "name": "Gastric triacylglycerol lipase", "aln": "----------------MWLLL-VTSVLSAFG----------GAHGLFGKL------------------------------------------GPKNPEANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKK-NSENI---GKRPVAYLQ--HGLIASATNWITNLP-NNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVE-FWAFSFDEMAKYDLPATIDFIVQ-----------------KTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTES----PFKKISLIPKFLLKVIFGNKMFMPHNYLDQFLGTEVCS-RELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMT--VPIAVWNGGHDILADPQDVAM---LLP-KLPN--LLYHKEILPYNHLDFIWAMDAPQEVYNEIVTMMAED--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07098-1", "uniprot_id": "LIPF_HUMAN", "id": "P07098-1", "name": "Gastric triacylglycerol lipase", "aln": "----------------MWLLLTMASLISVLG----------TTHGLFGKL------------------------------------------HPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKK-NSGNT---GQRPVVFLQ--HGLLASATNWISNLP-NNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVE-FWAFSFDEMAKYDLPATIDFIVK-----------------KTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKS----LINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCS-REMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMN--VPIAVWNGGKDLLADPQDVGL---LLP-KLPN--LIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5W064-1", "uniprot_id": "LIPJ_HUMAN", "id": "Q5W064-1", "name": "Lipase member J", "aln": "----------------------------------------------------------------------------------------------------MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNL---AQRVVVYLQ--HGLLTSASSWISNLP-NNSLGFILADAGYDVWMGNSRGNTWSRKHLYLETSSKE-FWAFSFDEMAKYDLPASIDFTVK-----------------QTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKS----PLIRMTYKWKSIVMAFSGNKDFLPKTSFKKFIGSKLCP-LQIFDKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPDLNLVHYNQTTSPLYNMTNMN--VATAIWNGKSDLLADPEDVNI---LHS-EITN--HIYYKTISYYNHIDSLFGLDVYDQVYHEIIDIIQDNL-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2A6-1", "uniprot_id": "LIPM_MOUSE", "id": "Q8K2A6-1", "name": "Lipase member M", "aln": "--MSEILSRVWTVSHRVEIWLLILVAYLLQR----------NVNSGHLPT------------------------------------------KAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQT-RLKKE---GSRPVVLLQ--HGLLGDASNWISNLP-NNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDE-FWAFSYDEMARFDLPAVINFILQ-----------------KTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARS----PGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCG-QMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMM--VPTAMWTGGQDWLSNPDDVKT---LLS-EVTN--LIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQE-PNLPQGTCRVKL-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA61-1", "uniprot_id": "D4AA61_RAT", "id": "D4AA61-1", "name": "Lipase", "aln": "--MSEILSRAWSVSHRVEIWLLILVAYLLQR----------NVNSGHMPT------------------------------------------KAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQT-QLKKE---GSRPVVLLQ--HGLLGDASNWISNLP-NNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDE-FWAFSYDEMARFDLPAVINFILQ-----------------KTGQKKIYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKS----PGTKFLLLPDMMIKGLFGRQEFLYQTRFFRQLFIYLCG-QMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMM--VPTAMWTGGQDWLSNPDDVKT---LLS-EVTN--LIYHKNIPEWAHVDFIWGLDAPHRVYNEIIHLMKQE-SSLPQGTCRVKL-------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYY2-1", "uniprot_id": "LIPM_HUMAN", "id": "Q5VYY2-1", "name": "Lipase member M", "aln": "--MLETLSRQWIVSHRMEMWLLILVAYMFQR----------NVNSVHMPT------------------------------------------KAVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLV-QPKKT---GSRPVVLLQ--HGLVGGASNWISNLP-NNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDE-FWAFSYDEMARFDLPAVINFILQ-----------------KTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKS----PGTKFLLLPDMMIKGLFGKKEFLYQTRFLRQLVIYLCG-QVILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMT--VPTAMWTGGQDWLSNPEDVKM---LLS-EVTN--LIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLMQQEETNLSQGRCEAVL-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M5-1", "uniprot_id": "LICH_MOUSE", "id": "Q9Z0M5-1", "name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "aln": "--------------MQLQGLVFVFTIGILLS----------RVPTGTVS--------------------------------------------AVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRK-NHFGK---GPRPVVYLQ--HGLLADSSNWVTNID-NSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDE-FWAFSFDEMAKYDLPASINYILN-----------------KTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASG----PLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCT-HVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMR--LPTALWSGGRDWLADINDITI---LLT-QIPK--LVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64194-1", "uniprot_id": "LICH_RAT", "id": "Q64194-1", "name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "aln": "--------------MQLLGRVICFVVGILLS----------GGPTGTIS--------------------------------------------AVDPEANMNVTEIIMHWGYP--EHSVQTGDGYILGVHRIPHGRK-NQFDK---GPKPVVYLQWRHGFLADSSNWVTNID-NNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDE-YWAFSFDEMAKYDLPASINYILN-----------------KTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASG----PMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICT-HVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQ--LPTALWSGGKDWLADTSDINI---LLT-EIPT--LVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38571-1", "uniprot_id": "LICH_HUMAN", "id": "P38571-1", "name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "aln": "------------MKMRFLGLVVCLVLWTLHS----------EGSGGKLT--------------------------------------------AVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRK-NHSDK---GPKPVVFLQ--HGLLADSSNWVTNLA-NSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDE-FWAFSYDEMAKYDLPASINFILN-----------------KTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTS----PMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCT-HVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDML--VPTAVWSGGHDWLADVYDVNI---LLT-QITN--LVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U4B4-1", "uniprot_id": "LIPN_MOUSE", "id": "Q3U4B4-1", "name": "Lipase member N", "aln": "-----------MPMMWLFLTTACLIPGTLSA----------GGFLDFEN--------------------------------------------KVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRA-QTGQT---GPRPVVYMQ--HALFADNAYWLENFA-NGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEK-FWAFSFNEMAKYDLPGIIDFIVN-----------------KTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTS----VFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCN-QKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMK--VPTAIWAGGHDVLVTPQDVAR---ILP-QITN--LRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K430-1", "uniprot_id": "A0A0G2K430_RAT", "id": "A0A0G2K430-1", "name": "Lipase", "aln": "-----------MPVMWLFLTTACLIRGTLSA----------GGF--FEN--------------------------------------------TVNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRG-QTGHA---GPRPVVYMQ--HALFADNAYWLENFP-NGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEK-FWAFSFDEMAKYDLPGIIDFIVN-----------------KTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKYPTS----IFTSFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVCN-KKLLRPMCSEFMSLWAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMK--VPTAIWAGGHDVLVTPQDVAR---ILP-QITN--LRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGLMKEYR-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VXI9-1", "uniprot_id": "LIPN_HUMAN", "id": "Q5VXI9-1", "name": "Lipase member N", "aln": "-------------MMWLLLTTTCLICGTLNA----------GGFLDLEN--------------------------------------------EVNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRT-HARST---GPRPVVYMQ--HALFADNAYWLENYA-NGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSETDEK-FWAFSFDEMAKYDLPGVIDFIVN-----------------KTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKYPTG----IFTRFFLLPNSIIKAVFGTKGFFLEDKKTKIASTKICN-NKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMK--VPTAIWAGGHDVLVTPQDVAR---ILP-QIKS--LHYFKLLPDWNHFDFVWGLDAPQRMYSEIIALMKAYS-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6RR30-1", "uniprot_id": "F6RR30_MOUSE", "id": "F6RR30-1", "name": "Lipase", "aln": "----------------MLWLLRTMCLIHLLG----------KLFCSFGTK--------------------------------------------KNPEAHMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKN-NANSS---APKMVVFCQ--HGLLATPGAWVSNLP-DNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNTDSKE-FWDFSFDQMIKYDLPATINFILD-----------------KTGQKQIYYIGHSQGTLIAIGAFATNQKLAEKIKLNILLAPIYSVQHSKG----IARLTSYLTPTTIKVLFGEKEFLPTVVSSEVG-AYVCD-INLVTAGCAAMIGSMGGYSPEQLNMSRLDVYVKLNLAGTSVKILIHYNQIRRSGILQAYDWGSSSLNMQHYNQTTPPVYNVEDMK--VPTAMFTGLKDFLSDPEDVEI---LKP-KIHN--LTYLKTIPDFSHFDFIWGLNAREEVSEEILTILRKYDGDYI---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3YY49-1", "uniprot_id": "D3YY49_MOUSE", "id": "D3YY49-1", "name": "Lipase", "aln": "----------------MLWLLRTMCLIQVLG----------KIFCLFGPK--------------------------------------------KNPEAHMNVSEIIKHWDYPSEEYEVVTDDGYILPINRIPHGKN-NAKSP---APKMVVFCQ--HGLLATPGAWVSNPP-VNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNPDSKE-FWDFSFDQMIKYDLPATINFILD-----------------KTGQKQIYYIGHSQGTLLAIGAFATNQKLAEKIKLNILLAPIYSVQHSKG----ISHLASYLTPTTIKLLFGEKEFLPTVVFSEVG-ACVCN-INFFTAICAAIMGSMGGYSPEELNKSRLDVYVKLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLNMRHYNQTTPPVYNVEDMK--VPTAMFTGLKDFLSDPEDVEI---LKP-KIHN--LTYLKTIPDFSHFDFIWGLNTREEVSEEILTILRKYDGDYI---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6WYC8-1", "uniprot_id": "F6WYC8_MOUSE", "id": "F6WYC8-1", "name": "Lipase", "aln": "----------------MLWLLRTMCLIHVLG----------KIFCLIGPN--------------------------------------------KNPESNMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKN-NANSS---APKMVVFCL--PGLFSTAGVWVSNPP-DNSLAFILADAGYDVWLGNNRGSTWAKKHVTLNPDSKE-FWAFSYDEMIKYDLPAIINFILE-----------------KTGQKQIYYAGHSQGTLIALGAFATNQELAEKIKLSILIAPIHTVKYVKG----SGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLS-QHVCD-IKLVDAGCATVLGSLTGYSPEQLNTSRVDVYITHSLAESSVQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMK--VPTAMFSGLKDFLSNPEDVAN---LVP-KISN--LTYHKIISDFSHLDFITGLNAREEVSEEILTILRKYDGDIQI--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A494BBH0-1", "uniprot_id": "A0A494BBH0_MOUSE", "id": "A0A494BBH0-1", "name": "Lipase", "aln": "----------------MLWLLRTMCLIHVLG----------KIFCLIGQN--------------------------------------------KNPESNMNVSEIIKHWEYPSEEYEVVTDDGYILPINRIPHGKN-NANST---APKMVVFCL--HGLFSTAGIWVSNPP-DNSLAFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKE-FWAFSYDEMIKYDLPAIIKFILE-----------------KTGQKQIYYTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKG----AGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLS-QHVCD-IKLVDAGCATVLGSLTGYSPEQFNTSRIDVYITHSLGESSIQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMK--VPTAMFSGLKDFLSNPEDVAN---LVP-KISN--LTYHKIISDFSHLDFIMGLNARKEVSEEILTILRKYDGDIQI--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUQ1-1", "uniprot_id": "D3ZUQ1_RAT", "id": "D3ZUQ1-1", "name": "Lipase", "aln": "----------------MWWLLRTMCLIHVFG----------KIFCLLEPN--------------------------------------------KNPESHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGKN-NANSS---APKMVVFCQ--HGLFSTPGVWVANPP-DNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEE-FWAFSFDQMIAYDLPATINFILN-----------------TTGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVKYVKG----FGRLLAYFSPEAFKLVFGKKEFLPTVVFSEYS-KYVCN-IKLVDAGCAGVLGSLTGFSEDQLNTSRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENMK--VPTVMFTGLKDFLADPKDVAN---LVP-KIFN--LIYHKTIPEFSHLDFIVGLNAKTEVSDEILTILGEYDSSVL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7L1-1", "uniprot_id": "M0R7L1_RAT", "id": "M0R7L1-1", "name": "Lipase", "aln": "----------------MWWLLRTLCFVHVIG----------SIFCFLNAKP-------------------------------------------KNPEANMNVSQIISYWGYESEEHEVMTEDGYILLIFRIPHGKN-ENKSSHN-TRRPVVYLH--HGLTVSADYWILDPP-SNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKE-FWDFSFNEQIEYDLPAIIYFILN-----------------ETRQTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVVITKYLTG----VFRTIAYIHPTVIKTMFGEKDIFSKSNANDIL-RFLCH-REQIATACTSLLIVLFGYNPGNLNESRIDVYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYNIEDMK--VRTAMWSGERDLLGDPKDVKN---LAA-KTPN--LIYHKKIPHYNHMDFILGKDAVVQVYRKIIEFINRDQSE-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PCU5-1", "uniprot_id": "M9PCU5_DROME", "id": "M9PCU5-1", "name": "", "aln": "------------------MCINSKNNTHIHPSGVVDCTLIALSLCLLQSGIVEGISLSLGDITLFNVNFKTPTFLGRSVAVDSNVRLENDVDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIARPGATP--------------VLLVHGLLDSSATWVMMGP-NKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAK-FWDFTFHEMGKHDIPATMDYILN----------------STG-VSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRS-PVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDH-GWLRNHWIYGTIDPPSYHLENVR--AKVALYYGQNDWLAPPEDVEM---LNR-KLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMR--------NHENSII-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKT8-1", "uniprot_id": "Q9VKT8_DROME", "id": "Q9VKT8-1", "name": "Lipase", "aln": "------------------MSLSSSSKFLIWT--------FFLGLFQLEA----------------NAFFNP---------------FQLAIPSSVLEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIARPGALP--------------VLLVHGLMDSSDTWVMMGP-SSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSD-FWNFSFHEMGIFDLPAIIDYILM----------------QSG-FGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRS-PIVNLLASQDTAVASFLSAAGYNEFLPSNSVIDQFKRYACRD-IISSSVCQSLFFILFGFNGQQVNQTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDY-G-LLNFLHYGSLSPPPYELEKVK--AKVAIYYAKNDWIAPPEDVDM---LFN-RLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQSVVPYSSYNDGDSITTVFVNRF------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKT2-1", "uniprot_id": "Q9VKT2_DROME", "id": "Q9VKT2-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "--------------------MPHAICILV-----------VLGIYTLDG----------------SGVLGG--------------FMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPGAKP--------------VLLVHGLEDTSSTWIVMGP-ESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQ----------------KTG-YQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKA-PLMGIARMGMNMFGDNFELFPHSEVFLN----------QCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDY-ESKENQRLYGRSTPPDYRLERIK--APVALYYGSNDYLSAVEDVHR---LAK-VLPNVVENHLY--RKWNHMDMIWGISARRSIQPRILQVMQYWETGGGGTKDGTTGSPVEEDVPQLTTETPIEEGTTQGDEKIGNVQGNEEQGHAEETEQVQVTTSPTSEL------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKT7-1", "uniprot_id": "Q9VKT7_DROME", "id": "Q9VKT7-1", "name": "Lipase", "aln": "------------------MLKSCHLNYCYG---------ILISLFIFCD-----------------TASGDLIK----------------VDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIPKPGGQP--------------VLLVHGLLDSSVAYVILGP-ERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQ-FWDFSFHELGVYDLPAAIDYVLA----------------RSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDS-PIILTFVKYLRPLVFIARSFGIYEFPPENEVWRSLIHKICS--FVFQNTCTYFLMEAMGVDYAQFNSSLLPLFTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVD--CKVALYYSRNDRLTSDKDVVR---LRD-ILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVDNGEV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKS5-1", "uniprot_id": "Q9VKS5_DROME", "id": "Q9VKS5-1", "name": "Partial AB-hydrolase lipase domain-containing protein", "aln": "----MRSTVEVKGRLLLTLLLHCLVALEVCGRA---GAFTLLSPFSYSS-----------------LSFKNLLNSVLLSSNPNLAGGGRNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQP--------------VLLMHGILDTSATWVLMGP-KSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQE-FWDFTFHEMGKYDLPANIDYILS----------------KTG-YEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKS-PLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDR-GYLRNQLEYNRMTPPDYDLSRVK--VPVALYYSVNDLLVSTTGVDR---LAR-ELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVENHRAKLTANLANYLAMQLQRQQLRQQMQQQMMEGLPPNVHLPHGLGMEMLARATTFAPVTHPTTTMTMPTTTTENDAEDEVLTTAATATEVPA----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKS9-1", "uniprot_id": "Q9VKS9_DROME", "id": "Q9VKS9-1", "name": "Partial AB-hydrolase lipase domain-containing protein", "aln": "--MAIAFNIAIYAIILVGSLVPSKTQEWVPYAYPVDENQGLNEQTQWQSQ--SQIQSQGTSQSQSQAQIQSQPEPRSCLQCQQASYQQFFAEVDIQIDAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPRSGATP--------------VLLVHGLMASSATWVQFGP-SQGLAYILSQSGYDVWMLNTRGNVYSEERLAG-RESDKIFWDFSFHEIGQYDLPAAIDLILL----------------QTK-MPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRS-PALKFMKLFSGGFTMLLNLLGGHKISLKNKIVDMFRNHICTK-LIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYDY-GLILNKIRYQSIFPPLYNLSLAL--GKVALHRGDGDWLGSESDVLR---LER-DLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISLCGSNR-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O46107-1", "uniprot_id": "LIP1_DROME", "id": "O46107-1", "name": "Lipase 1", "aln": "----------MRCSLRMQLLLLLGLCVFISR---------IQGQLIGGE----------------EDEEDEEEEEEEEESVEDETPEDRLQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRKQGAPP--------------FLLQHGLVDSSAGFVVMGP-NVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESK-FWDFSWHEIGMYDLPAMIDHVLK----------------VTG-FPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSS----IREMFNG------EFRFLCRMTEETERLCIEAVFGIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSY-SSNKNMQLYRDHLPPRYNLSLVT--VPTFVYYSTNDLLCHPKDVES---MCD-DLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGKVPEGSPEEANRSRREIRGKFIRS----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9N3-1", "uniprot_id": "Q9V9N3_DROME", "id": "Q9V9N3-1", "name": "Lipase", "aln": "----------------MLDNNSCAQTNILTS----------KEMANNSPTRGSVMLLT--------------------------LVLLLLSRKIGLVDGHKVTATSISNHNYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAG----RRAVVFLQHGILSASDDWIINGP-EASLAYMLADAGYDVWLGNARGNTYSRQHKHIHPDTSD-FWRFSWHEIGVYDLAAMLDYALA---------------KSQSSS--LHFVAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPS-FLSWVLGSMELLPITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAGASSSQVIHYLQLYRSGDFRQYDHG-PELNEIIYQQPTPPSYNVQYIK--SCVDMYYSENDYMSAVGDVKY---LAS-LLP-CAQLYRIPFRDWNHYDFLWSNNVKEVINNKIIQKIRKYDEDGVGF-------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG46-1", "uniprot_id": "Q9VG46_DROME", "id": "Q9VG46-1", "name": "Lipase", "aln": "----------------MRRERVVLLCLALLG----------LQQVSRATLR--------------------------------------QSREIIITD----AVRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDP--ELGSLL----RRPVVFLLSGLYASSDVWLLNGR-EDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTERE-FWDFSWHEMGVYDLPAQVDYVLR---------------TTGQKA--MHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVIGPVLGTRN-YVSKMLEGVEMFSTNKFFKKFLSMTCLENEKPLVCISRLWPAVG-YDTRFLNKTLLPDLMANFPAGGSVKQLMHYFQGYVSTRFRQYDYG-PERNWLHYQQLEPPEYALENVS--TPVTVFFSENDYIVAPADIWR---LLT-RLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYEQRRR---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O46108-1", "uniprot_id": "LIP3_DROME", "id": "O46108-1", "name": "Lipase 3", "aln": "----------------MTRG-ALKVTILLVG----------LGLVLAGSRP--------------------------------------------ISD----CGERIEDDGYPMERHEVVTSDNYILTMHRIPYSPK---TGESS----NRPVAFLMHGMLSSSSDWVLMGP-ERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQI-FWNFSWNEIGMYDVPAMIDYVLA---------------KTGQQQ--VQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPILGQPN-AIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYT-ALRNPYEYGSYFPPDYKLKNAK--APVLLYYGANDWMCDVSDVRK---LRD-ELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQSYE-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQQ5-1", "uniprot_id": "Q9VQQ5_DROME", "id": "Q9VQQ5-1", "name": "Lipase", "aln": "-----------------------MLAKVLTI----------LAIVASAG-----------------------------------AADDFDPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGP-EDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPY-FWKFSWHEIGSIDLPATIDYILA---------------ETGQQS--LHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHG-IGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWG-SKRNLEYYGVSEPPAYDLTKIT--SELYLYYGLADGSANKQDISR---LPD-LLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYDARETNNEI-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE9-1", "uniprot_id": "Q9VPE9_DROME", "id": "Q9VPE9-1", "name": "Lipase", "aln": "------------------------MNPIFCA----------LLFSLVAG-----------------------------------LVLAEK--SDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLK-NQNE-----KRPPILLQHGLFSNSDCWLSSGP-DNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHK-FWHFDWHEIGTIDIPAMIDYILA---------------DTGFDQ--IHYAGHSQGTTVYLVMLSERPEYNALIKSGHLLAPCAFFEHGTSFIFNALGPLVGTPGGIWNQLLVDTELIPNNNLVNRLVDNSCH---LSNTICNNAFIMFANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWG-TKKNNELYGQDLPPDYDLSKIV--APTHLYSSTNDALCGPEDVNT---LVE-NFPHLTEDYRVPVQSFNHLDFIIAKNMKELVNDPIIERINSYEGR-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBK6-1", "uniprot_id": "Q9VBK6_DROME", "id": "Q9VBK6-1", "name": "Lipase", "aln": "--------------------MNR-FTGSLLV----------LVALAVG--VYSAAIDG----------------------PIDFYKLYDNPEAHISLKSKITTADRTAAHGYPSEHHHIVTEDGYILGVFRIPYSHKLQ-NQNE-----KRPIVLLQHGLTSCSDAWILQGP-NDGLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPN-FWKFSWHEIGIYDITAIIDYALST--------------ENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYLGHRN-TYSVLFGSQEFLPHNEFLMAIFFNICQPDFMLRPVCESAMEKLYAG--GRVNMTAMPEGMATHPAGCSTDQMLHYLQEQQSGYFRLFDHG-TKKNLEVYGTQEPPEYPVELIN--SLVHMWYADSDNLAAVEDVEQ---IAE-RLPN-KVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMMEYELKNIGT-------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMS3-1", "uniprot_id": "Q8IMS3_DROME", "id": "Q8IMS3-1", "name": "Lipase", "aln": "--------------------MYRSHIAVICA----------FVGIFVGTVVQSAPFSND------------------PAEVPNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQ-NQQE-----KRPIAFIQHGLFASSDFWPSLGP-DDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPD-FWRFSWHEIGYFDIAAAIDYTLST--------------ENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVNTLSPYLGFNN-IYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEE--GRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFG-TKKNMKVYGTEAPEDYPTELIT--AEMHLWYSDSDEMAAVEDVLR---VAE-TLPN-KVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEYEGK-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KI77-1", "uniprot_id": "Q0KI77_DROME", "id": "Q0KI77-1", "name": "Lipase", "aln": "--------------------MSYKAFVFFCL----------YIDLAKG----------------------------------------------------LITSEIIASHNYPVEVHTVLTRDGYLLDAFRIPGSKFCQ--QSG-----PKPAVLFQHGMSASSDVFLLNGP-QDSLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEA-FWRFSWHEIGTEDVAAFIDYILD---------------TTKQRA--LHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPAVFMRHTSTLSQTVFRSFIMAMP--------DKEFMYHNGVLNKLLSNVCG-LFVARVFCTTFFLISNGKISKHLNTSVIPLIAATLPAGVSSRQPKHFIQLTDSGKFRPFDFG-ILRNLINYKSLEPPDYTLSNVRPLTPVHIFYSDDDSSTAKEDIQN---FAA-RVPE-VVMHRISTPGWHHTDFVHSMTVADVINKPVIEIFRSFER-LSSPTFL----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG50-1", "uniprot_id": "Q9VG50_DROME", "id": "Q9VG50-1", "name": "Lipase", "aln": "--------------------MPYKTLVILSV----------CTQIVNG----------------------------------------------------ITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCE--QSG-----TKPAVLFQHGMTASSDVFLVNGP-RDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDED-FWRFSWHEIGTEDVAAFIDYILG---------------TTNQSA--VHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVFMGHTHTLGQIFLRTLIMSMP--------DCEFMFHNRILNKILRRICG-LFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFG-ILRNLINYRSLTPPDYPLHNVRPLTPVHIFYSDDDLSAAKEDVEN---FAT-SLPE-AVMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRFEQPIDCKGSL----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG48-1", "uniprot_id": "Q9VG48_DROME", "id": "Q9VG48-1", "name": "Lipase", "aln": "--------------------MLLMELVIFFD----------WLLIVSGM------------------------------PKVKFGLQNFTGRGKDYRIKVITGILIIDKYGYSVETHTVRTGDGYILDMFRIPSSPNCK--EDG-----FKPSVLIQHGLISLADSFLVTGP-RSGLPFMLADRCYDVWLSNSRGVRYSQRHIRLKASQDA-FWRFSWHEMGMEDLPAMIDYILS---------------TTNEEA--LHFVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAVFMKHARNKLMKMFGNIIMSMK--------DSSFFGPLDAIRFLLSVFCK-CSKFKKLCAFMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYDFG-VMRNKKLYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVARKDIHI---LIS-KLDK-AVLHDVVFEKWSHSDFLFAKLIKKVVNEPIIKVIDHFENRQQ---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG47-1", "uniprot_id": "Q9VG47_DROME", "id": "Q9VG47-1", "name": "Lipase", "aln": "-------------MQSFLIQMLPILLGIFFV----------WLSNSTAL------------------------------SEVNW--KNHSLHRIHHRTKVITAVDIISSHNYPVQTHTVVTRDGYILSVFRIPSSQLCA--SSE-----PKPVVLINHGMTGSADSWLLTGP-RNGLPFLLADACYDVWLINCRGTRYSRKHLKLKAWLLQ-FWRFSWHEIGMEDLPATVDHILA---------------STKRNS--LHYVGHSQGCTSMLVMLSMRPEYNKRIRTTILLAPPVFLKHSLSMGHKIMKPLFNLLP--------DIELLPHHKMLNSAVSAICK-ILGVKDVCTALYLLTNGRVSQHMNRTLIPMLIATHPAGISSRQPRHFFQLKDSGRFRQYDFG-FGMNYLIYRQNTPPEYPLEMVRPHSAIHIFYSDDDGTISPRDVLT---LAS-KLPY-AVPHHITDETWNHMDFLLANNINELINNPVIKIIKTFEENIKHKIGNIKGEISIDALLNEF--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q59E63-1", "uniprot_id": "Q59E63_DROME", "id": "Q59E63-1", "name": "Lipase", "aln": "-----------------------MAPEEEEP----------EEEVARDS----------------------------------------------LCTRSDSVCQAVQRQQLQCQVHRIETADGYRLSLHRIPAPQNRWCPQQLR-------PFLLMHGLLGSAGDFVSGGR-GRSLALELHARCFDVWLANARGTTHSRGHRTLQTSDAR-FWRFSWHEIGIYDLPAIVDYVLA---------------RTNRRQ--LHYVGHSQGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLASDSSMAT-LLLNKLGLHELLPASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSDYPLDRSILPRILETTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVR--LQLQIFHGSRDTLSSLADVQR---LVR-ELRN-SVTQMYQVPGYNHIDFLFASSAPQVVFQRIIQQAWQLDMALAAL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKR5-1", "uniprot_id": "Q9VKR5_DROME", "id": "Q9VKR5-1", "name": "Lipase", "aln": "-----------MGGSGCIGAIKVMLIVCAIG----------RNAHSSPP----------------------------------------------ESRYKWTTMDWLEAQNVSHEVHNVTTADGYQLQLQRLPRLGAKP--------------VLLVHGLLGSSLGWVCMGP-ERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVR-------FDSFQVRRLMKFIKKRQKAYKFEIFPPGYFRKVCQAKRDLCEYYAKQLVGSAQNNKKLLEAFNYEYLLQ----GGSPREIKHLQQIWKSGDFISYDFG-TAENLQVYHSVEALSYNISQIT--VPIILYFGETDAIATPEGVHA---IYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQFFDGRLPYVIE----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34163-1", "uniprot_id": "TGL1_YEAST", "id": "P34163-1", "name": "Sterol esterase TGL1", "aln": "MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSS-------------------------------------DDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNK---------VVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNK-FWDFSIDEFAFFDIPNSIEFILD-----------------ITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHN---RIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLF--NLCIDIANKILFNWKSFNILPRQK---IASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIK--IPILLIYGGIDSLVDIDVMKKNLPFNS--------VFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTTHPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDTEDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : *: .: : * ::**: . ** . :* * .: *:. : : * . : . :.* : * * : :. * . : . * . : * : : :: ", "identical_positions": 17, "similar_positions": 38, "identity": "2.7%" }, { "cls_id": "homologset.agr.SGD:S000001624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z9-1", "uniprot_id": "Q641Z9_RAT", "id": "Q641Z9-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "------------MAALLLRHIGRHCLRAHLS-----------------------SQLCIRNAAPLGTTAKEEMARFWNKNTSSNRPVSPHLTIYRWSLPMAMSVCHRG----SGIAMSGGVSLFGLSALLLPGNFESYLMLVKSLCLGPALIHAAKFVLVFPLMYHSLNGVRHLMWDLGKGLSISQVQLSGVTVLVLAVLSSAGLAAI-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZB0-1", "uniprot_id": "C560_MOUSE", "id": "Q9CZB0-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "------------MAAFLLRHVSRHCLRAHLN-----------------------AQLCIRNAAPLGTTAKEEMERFWKKNTSSNRPLSPHLTIYKWSLPMALSVCHRG----SGIALSGGVSLFGLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSGVAVVVLAVLSSGGLAAL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99643-1", "uniprot_id": "C560_HUMAN", "id": "Q99643-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "------------MAALLLRHVGRHCLRAHFS-----------------------PQLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRG----TGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S5Q2-1", "uniprot_id": "B0S5Q2_DANRE", "id": "B0S5Q2-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "-------------MALLLRTVARQGLYSSRSQ----------------------FGVLYRHAVPMGTTSNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRG----TGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVLTSIGLAAM-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGT9-1", "uniprot_id": "Q9VGT9_DROME", "id": "Q9VGT9-1", "name": "", "aln": "MNTCRSLARGLNICSPQLRHLLAQKPFNSARLLATKAPKDHKASGPTTIGPSGDILVPPVTLKVIPFRMPP-DLPYDDRNMLLGRQLSPHLSIYKIQLTSTLSAFLRI----SGFVLAVFVWFVGISGLCLQGDMEGFIKKVEKCDCHG-MVTMAKVMVTMPFAYHTVAGTRHLIWYLNKFLTIPEIYATGYVAVALTIALSAFLLAVKVGEKVKEEVVDLTKTKKGQKAKKEAPKDAKKDAPKDTKKEPKKDAKDKKKDEEGKSAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS3-1", "uniprot_id": "Q9VGS3_DROME", "id": "Q9VGS3-1", "name": "", "aln": "---MYALSSSL-IRSPALRQGLQMAAAS-----------------------------RPVSMKVVSVAETQKDESFFEKNERLGRELSPHLTIYQPQLTSMLSICHRG----TGLALGVGVWGLGLGALISSHDISHYVTMVEGLQLSGATLTALKFIIAYPAGYHTANGIRHLLWDTGRFLKIKEVYSTGYAMVATSFVLSAILALL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33421-1", "uniprot_id": "SDH3_YEAST", "id": "P33421-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial", "aln": "-MSAMMVKLGLNKSALLLKPSAFSRAAALSSSRRLLFN---------TARTNFLSTSPLKNVASEMNTKAAIAEEQILNKQRAKRPISPHLTIYQPQLTWYLSSLHRISLVLMGLGFYLFTILFGVSGLLGLGLTTEKVSNWYHQKFSKITEWSIKGSFAYLFAIHYGGAIRHLIWDTAKELTLKGVYRTGYALIGFTAVLGTYLLTL-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: .: * :***::** .:. :* * *: : ..:..* : * .. * . *** * : : : : :* . : : . * : ", "identical_positions": 19, "similar_positions": 32, "identity": "7.12%" }, { "cls_id": "homologset.agr.SGD:S000001626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FR7-1", "uniprot_id": "LTV1_RAT", "id": "Q68FR7-1", "name": "Protein LTV1 homolog", "aln": "MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADETAPQRVLVPTQK-----------VNDEERRAEQRKYGVFFDDDYDYLQHLR--EPSGPAELIPSSTPSTYSSRGE--------EDTSVFPSTGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDFDFDDPENLLEDDFILQASKPTGGE-GMDMLESDGDDGNEWEDMD-EGGS--DGCGSTGPLSDGGDISAPGSPREAMKKHLFWEEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDVE-IGALDNAELEGTIQVDSSRLQEVLNDYYKE-KAENCVKLNTLEPFEDQDLAAN---ELDESEKEETVTVVLEEAREKWDCESICSTYSNLYNHPQLIKYEPK---------PKQIHLSSKTGIPLHVLP---KKGLTAKQVERMQMIN-----------SSDLPKVSTQ-PRLKTESKEDKKARKQAIKEERKERRVEKKANKLAFKLEKRRQEKELLNLKKNVEGLKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NSQ7-1", "uniprot_id": "LTV1_MOUSE", "id": "Q6NSQ7-1", "name": "Protein LTV1 homolog", "aln": "MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADETAPQRVLLPTQK-----------VNDEERRAEQRKYGVFFDDDYDYLQHLK--EPSGPAELIPSTSFATPLCDKT--------EDPCVYSSTGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDFDFDDPENLLEDDFILQANKPTGGE-RMDT-ESEEDDGHEWEDMDDEEGS--DDRSSAGFLSDGGDLSAPGSPQEAMKKHLFWEEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDVE-IGALDNAELEGTIQVDSNRLQEVLNDYYKE-KAENCVKLSTLEPFEDQDLPTN---ELDESEKEETITVVLEEAKEKWDCESICSTYSNLYNHPQLIKYEPK---------PKQIHLSSKTGIPLNVLP---KKGLTAKQVERMQMIN-----------GSDLPKVSTQ-PRSKDETKEDKRARKQAIKEERKERRVEKKANKLAFKLEKRRQEKELLNLKKNIEGLKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GA3-1", "uniprot_id": "LTV1_HUMAN", "id": "Q96GA3-1", "name": "Protein LTV1 homolog", "aln": "MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADESAPQRVLLPTQK-----------IDNEERRAEQRKYGVFFDDDYDYLQHLK--EPSGPSELIPSSTFSAHNRREEK-------EETLVIPSTGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDFDFDDPDNLLEDDFILQANKATGEEEGMDIQKSENEDDSEWEDVDDEKGDSNDDYDSAGLLSDEDCMSVPGKTHRAIADHLFWSEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDDE-IGALDNAELEGSIQVDSNRLQEVLNDYYKE-KAENCVKLNTLEPLEDQDLPMN---ELDESEEEEMITVVLEEAKEKWDCESICSTYSNLYNHPQLIKYQPK---------PKQIRISSKTGIPLNVLP---KKGLTAKQTERIQMIN-----------GSDLPKVSTQ-PRSKNESKEDKRARKQAIKEERKERRVEKKANKLAFKLEKRRQEKELLNLKKNVEGLKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3J8-1", "uniprot_id": "LTV1_DANRE", "id": "Q5U3J8-1", "name": "Protein LTV1 homolog", "aln": "MPHRKKKSFINKKNAVSFHLVHRSQKDPLAADETAPQHVLLPTVR-----------VELEKRKEEQRNFGVFFDDDYDYLQHLR--ESTQTAELISAPRVRRDTRLKPADDEEHMKEEDSSVSEASIKLPSSVFASEFEEEVGLLNKAAPISGPRLDMDPDIVAALDEDFDFDDPENMLEDDFIIKASDVMGGG--------GGEDDDEWEDTDDDDGE-EQDFDSEAGLSDDE--------EGGRREFMFADCETKTRFTEYSLTSSVMRRNEQLTLLDDRFDEFYKQFDDDE-IGALDNAELEGYIEPDSARLEEVIKDYFIQ-KEKDCQKPDQLGPAELPSVREEDEEDEDADEELETERMVIEPPAERWDCETIISTYSNLYNRPKLIQDPPK---------PKQIRVSSKSGIPLDVLP---KRGLTVKQVERMERIN-----------DSDLPRVSTQ-PRSRDENTEERKARKQAIKSERKERRTKKKANKLAFKQEKQMQEKQMVHLRANVQGMKLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KN79-1", "uniprot_id": "LTV1_DROME", "id": "Q7KN79-1", "name": "Protein LTV1 homolog", "aln": "-MVKGKKPYIDRKKAVTFHLVHRSQHDPLVTDENAPQRVLLEAAARQQKPKDPEPPTDPAQRQEELKKFGIHFDDDYDYMQHLKKRENDVVWEFMENPNQARKQKVQDS-------EKPG--PAPKLMLPSSVFASEFEESEGMLNKAAPQT-LRLDWDPDVVAALDSDCENEE----LEDDFVIQAMAE------------GDSDDEEWDDEDGEEQS-DMDFDSDDLNEDENEDELMDRLAPLMRERRFDDEEVKSRFTEYSMSSSVIRRNEQLSLLDDRFEKFYATYDDPE-LGDLALEDIEGNWHQKHPVVMQCFQEFKKKDKGIEYNKEWDRERIEKYRNVVE---GEEDPTEELVEYEVDDPKQKKWDCESILSTYSNIYNHPKVIDEPRRSRRSSASTNPAPIQIDPKTGLPTNVLRGGVDGQLTAKALANLADESPAATGPKSLCAKSVLSTLSVLSIRPKDETHEEKKERKRLLKDYRNERRIEKKANTEAFKEEKKRQTHVKINQRTNQQGASIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34078-1", "uniprot_id": "LTV1_YEAST", "id": "P34078-1", "name": "Protein LTV1", "aln": "-----MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLVPVSN-----------PNKTSPEADLRKKDVSSTKPKGRRAHVG--EAALYGINFDDSEYDYTQHLKP----------------IGLDPENSIFIASKGNEQKVEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRGFKPDMNPALREVLEALEDEAYVVNDDVVVEDISKKTQLQGDNYGEEEKEDDIFAQLLGSGEAKD-EDEFEDEFDEWDIDNVENFEDENYVKEMAQFDNIENLEDLENIDYQADVR-RFQKDNSILEKHNSD-DEFSNAGLDSVNPSEEEDVLGELPSIQDKSKTGKKKRKSRQKKGAMSDVSGFSMSSSAIARTETMTVLDDQ----------YDQIINGYENYEEELEE---DEEQNYQPFDMSAERS------------DFESMLDDFLDNYELESGGRKLAKKDKEIERLKEAADEVSKGKLSQRRNRERQEKKKLEKVTNTLSSLKF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. *:: : :***.: ** * *. :**: . : . . : :: .: . . *: * : . : .*:* :. :. : :* . . * : * : * : : . :* . . . : . *.* *:. . :: .: *:.: : :*: * : * : :. . . ::.. . . . * : : : * . : : * : . : : :. . .: . . : . . . :. . . *. : :* . :* : . .. : : ::. * : :. * . ", "identical_positions": 34, "similar_positions": 118, "identity": "6.48%" }, { "cls_id": "homologset.agr.SGD:S000001627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FCX9-1", "uniprot_id": "F7FCX9_RAT", "id": "F7FCX9-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVS-LGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGA-HDLYMDTGEEIRFRVVDESFVDTSPTGP----------SSAEAASSSEELPKKEAP--YTLVGSISEPGLGLLSWWTSN-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2C6-1", "uniprot_id": "RPC8_MOUSE", "id": "Q9D2C6-1", "name": "DNA-directed RNA polymerase III subunit RPC8", "aln": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVS-LGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGA-HDLYMDTGEEIRFRVVDESFVDTSPTGP----------SSAEAASSSEELPKKEAP--YTLVGSISEPGLGLLSWWTSN-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y535-1", "uniprot_id": "RPC8_HUMAN", "id": "Q9Y535-1", "name": "DNA-directed RNA polymerase III subunit RPC8", "aln": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVS-LGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGA-HDLYMDTGEEIRFRVVDESFVDTSPTGP----------SSADATTSSEELPKKEAP--YTLVGSISEPGLGLLSWWTSN-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTL6-1", "uniprot_id": "Q9VTL6_DROME", "id": "Q9VTL6-1", "name": "DNA-directed RNA polymerase III subunit RPC8", "aln": "MFVLAELKDNVRIAPDQFHLKLVDAVRDEIDRKLANKVLLNVGLCIALKDIVSLKDSIILPGDGASHTEVLFRYVVFRPMVGTVITGKIRNCSREGVHVT-LGFFDDILIPHAALQHPSRFDEAEQAWVWEYPLEDGAKHDLFMDVGEPIKFRVSREIFEETSPIGPPKTEAQTQQGASTSAAVASATSQEVKTP--YRIIGAINESGLGVLSWWDQQGKDDEQDDEEDEEYDDEDGEGACEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35718-1", "uniprot_id": "RPC8_YEAST", "id": "P35718-1", "name": "DNA-directed RNA polymerase III subunit RPC8", "aln": "MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCYYTPEESAWIWP--MDEET--KLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :: * ***.* **. . .:: .:::.*:***:: ****** : *: .:::. : ****:*: :* ** ***:*::. :: * * *: **::*: **:****:** * . . : *..*:* :: : .*::*..* *:**: * * :..* .* . . . : : * * ::*: . *:*::*** ", "identical_positions": 69, "similar_positions": 72, "identity": "28.4%" }, { "cls_id": "homologset.agr.SGD:S000001628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63347-1", "uniprot_id": "PRS7_RAT", "id": "Q63347-1", "name": "26S proteasome regulatory subunit 7", "aln": "MPDYLGADQRKTKEDEKDDKP----IRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIIN------------------------------ADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIPVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35998-1", "uniprot_id": "PRS7_HUMAN", "id": "P35998-1", "name": "26S proteasome regulatory subunit 7", "aln": "MPDYLGADQRKTKEDEKDDKP----IRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIIN------------------------------ADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46471-1", "uniprot_id": "PRS7_MOUSE", "id": "P46471-1", "name": "26S proteasome regulatory subunit 7", "aln": "MPDYLGADQRKTKEEEKDDKP----IRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIIN------------------------------ADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33299-1", "uniprot_id": "PRS7_YEAST", "id": "P33299-1", "name": "26S proteasome regulatory subunit 7 homolog", "aln": "MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :: *: ::.*.** * .* **** :**:** :.*: ::**.*:*:::: :*:* :*:*********. ***: .*:* * .*:***********: *.**.**:**:**:*****.*.::*:**************.**:*.:****:***:**** ****************:********** *** ****..***:****:**:******************** ** *******************************:********:***********************.*************::*****:******:****:***:**********::**:**::******.**:**::**********:*****************:*******:**:***..* ***:*.*** **", "identical_positions": 325, "similar_positions": 81, "identity": "69.59%" }, { "cls_id": "homologset.agr.SGD:S000001629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHK3-1", "uniprot_id": "S36A2_MOUSE", "id": "Q8BHK3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSARSPQVATPLNLDL---PESAKKLQSQDP---------------------------------------------------------SPAN-GSSSESSKKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVN-----STTISCHKNE--TVVLTPTMDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEIPDASQLP-LVAS--WKTYPLFFGTAIFSFESIGVVLPLENKMKDARGFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQV-----SKRWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYG----EGISPLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNSTMFIQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K415-1", "uniprot_id": "S36A2_RAT", "id": "Q8K415-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSAGSPQVAATVKLDLVSFPESAKKVQSQDP---------------------------------------------------------NPVN-GSSSESSEKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLASSPNTWLQSHAHWGRHAVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVN-----STTISCHKNE--TVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIGQYIIQGIPDPSQLP-LVAS--WKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTHALQFYVPAEIIIPLAVSQV-----SKRWALPVDLSIRLALVCVTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTYYG----EGMSPLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNSTMFIQ-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4D3-1", "uniprot_id": "S36A1_MOUSE", "id": "Q8K4D3-1", "name": "Proton-coupled amino acid transporter 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGL---------------------------------------------------------GSFS-PGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRL-NKPFLDYGDTVMYGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEAAN-----GTTTNCNNNV--TVIPTPTMDSRLYMLSFLPFLVLLSFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRIPDPSHLP-LVAP--WKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFP---LILYLGMAIITVLYISLGSLGYLQFGANIKGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSRV-----PEHFELMVDLCVRTAMVCVTCVLAILIPRLDLVISLVGSVSSSALALIIPPLLEVVTYYG----EGISPLTVTKDALISILGFVGFVVGTYESLCELIQPSHSDSSTNSTSAFI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924A5-1", "uniprot_id": "S36A1_RAT", "id": "Q924A5-1", "name": "Proton-coupled amino acid transporter 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGL---------------------------------------------------------GSFS-PGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRL-NKPFLDYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAAN-----GTTTNCNNNE--TVILTPTMDSRLYMLTFLPFLVLLSFIRNLRILSIFSLLANISMFVSLIMIYQFIVQRIPDPSHLP-LVAP--WKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFP---LILYLGMAIITVLYISLGSLGYLQFGADIKGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSRV-----PERFELVVDLSARTAMVCVTCVLAVLIPRLDLVISLVGSVSSSALALIIPPLLEVTTYYG----EGISPLTITKDALISILGFVGFVVGTYESLWELIQPSHSDSSTNSTSAFI-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2H8-1", "uniprot_id": "S36A1_HUMAN", "id": "Q7Z2H8-1", "name": "Proton-coupled amino acid transporter 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGL---------------------------------------------------------NNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRL-NKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAAN-----GTTNNCHNNE--TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLP-LVAP--WKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFP---LILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRA-----PEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYS----EGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q811P0-1", "uniprot_id": "S36A3_MOUSE", "id": "Q811P0-1", "name": "Proton-coupled amino acid transporter 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNVPLLREV---GKCQRNMFGRSTASSKGSSNSR---------------------------------------------------------SSSSTSPKKGPRREADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRL-QRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAH-----FTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-TPHHSNLP-LVAN--WKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNLP-ICWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRV-----SENWALFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYS----ENISCATIVKDIMISILGLLGCVLGTYQALYEMTQQTH-FYMANSTRVHI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B1-1", "uniprot_id": "S36A3_RAT", "id": "Q4V8B1-1", "name": "Proton-coupled amino acid transporter 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKTPLLRED---GRCQRNTFGGSKASSKGSSSSS---------------------------------------------------------SNNTVSSKKKPRRKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRL-QRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAH-----FTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEYLIQ-IPHHSHLP-LVAS--WKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGADTQASITLNLP-NCWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRA-----SENWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIATFYS----ENISCTTIAKDIMISILGLLGCVLGTYQALYEMTQQSR-FPMLNSTNVHT-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CH36-1", "uniprot_id": "S36A4_MOUSE", "id": "Q8CH36-1", "name": "Neutral amino acid uniporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAPAPAETAGCEELDMD-----VMRPLINEQNFDGSSDEEQE---------------------------------------------------------QTLVPIQKHYQLDGQHGISFLQTLVHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRF-KKSTLGYSDTVSFAMEASPWSCLQRQAAWGRQVVDFFLVITQLGFCSVYIVFLAENVKQVHEG----FLGSTPIVSNGSDLSHACERRSVDLRVYMLCFLPLIILLVFIRELKNLFVLSFLANISMAASLVIIYQYVVRNMPDPHNLP-IVAG--WKKYPLFFGTAVFAFEGIGVVLPLENQMRESKRFP---QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGVTARL-----HAKWKRICEFGIRSLLVSITRAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSK----DHYNIWMILKNISIAFTGVVGFLLGTYVTVEEIIYPTTAVVAGTSQSPFLNVNSTCITSGL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L655-1", "uniprot_id": "A0ABK0L655_RAT", "id": "A0ABK0L655-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCQPFMVVFNKGIYNKDMD-----VMRPLINEQNFDGSSDEEQE---------------------------------------------------------QTLLPMQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRF-KKSTLGYSDTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEG----LLETTVVVSNSSDLSQVCERRSVDLRVYMLCFLPLLILLVFIRELKSLFVLSFLANISMAASLVIIYQYVVRSMPDPHNLP-IVAG--WKKYPLFFGTAVFAFEGIGVVLPLENQMRESKRFP---QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPAVTARL-----HAKWKCICDFGIRSLLVSITCAGAVLIPRLDIVISFVGAVSSSTLALILPPLVEILTFSK----DHYNVWMVLKNISIAFTGFVGFLLGTYVTVEEIIYPTTAVADGASQSLSLNVNSTCVSSGL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ACD6B732-1", "uniprot_id": "A0ACD6B732_DANRE", "id": "A0ACD6B732-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASADQLDME-----VMTPLMEKAEGD---EEEED---------------------------------------------------------ENVDGDEDSKHLP--QGITFTQTLLHLLKGNIGTGLLGLPLAVKNAGIVLGPVSLVLMGVVCVHCMHILVNCSHQLSERL-KRSPLGYSETVAAAMELSSSQCLRRGAHFGRHLVNFFLVLTQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASAVSSVAIDLRLYMVFLLPFIIVLTFIRDLRNMAALSAIANLCMAISLIFIFSYILNDLSDPRRLP-YAST--WRKFPFFFGTAIFAFEGIGVVLPLENQMREPKRFP---QALNIGMGFIIVLYVTLATLGYLRFRDDIKGSITLNLPHDSWSNQLVKVLYSFGVFVSFAVQFFVPAEILLPPMCERV-----RKSWRRVADLSLRALLVCLTCVTAVLIPRLDLVISLVGAVSSSALALVFPPLVELIAFPS----QPPPPMLLLKDISIAALGFIGFLTGTYVTVEEIIYPDVQGQIRLHDDGNWTTPTTSTP---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V5R4-1", "uniprot_id": "POLYP_DROME", "id": "Q4V5R4-1", "name": "Glutamate transporter polyphemus", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKSQDQAPNRDDPDLQTEPLTIAQS-----------------------------------------------------------------ITSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRR-RVPQVSMPEAVRIAYEEGP-KWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIER----------------------YNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPNINDRE-MVTPP-VEWI-EFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSE----PRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYN--VGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF---------------------QLTLNSM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQF3-1", "uniprot_id": "Q8IQF3_DROME", "id": "Q8IQF3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDKGG--------------------------------------------------------------------------------------------FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRM-QIGYATYPVAMVYSFDQGP-RFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFYWVV----------------------ADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPPITERN-ILFGR-IDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKN----GDLPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPETTAEETTANMSATLTTALTAAPPDALRFRFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "id": "Q9W056-1", "name": "Proton-coupled amino acid transporter-like protein acs", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDDIKT--VTVYPTTLELTTPTKSA-----------------------------------------------------------------NGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQ-RVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV----------------------WDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERD-PFVA--AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKR----FKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYT--EGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD5-1", "uniprot_id": "Q9VTD5_DROME", "id": "Q9VTD5-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTRRRRLDQKLPFHQRLLGGVQNS-----------------------------------------------------------------FGSPLANEARLSSKKDNGMSDLEAFINVLKCGFGTGCLAMPYAFLNSGWLVGLICTFALGFFVLYAMHILLHHINNLGVQH-NMPMISYRKAVELSIRKGP-SIFHFLSKPFGYLVDILLCAYHFGVDCVYVVFIAKSLKHLGDMYLWV----------------------WDERLYMALIASPLILTFLIRNLKSLVPFSIISNILLLTGYCVILNYLFRDLPEFEHLH-AIQP--LRNFPIFFGTVLFSIESVGVILSLGRSMRKPESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFFSYALQGYVTVDIIWRNYLEPE----LEDRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLAQLGLILPGIVDICLRYE--EDYGPGKIFLIRSMLFICMGLAGGVAGTVVTLQTLYARYPVVRG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD7-1", "uniprot_id": "Q9VTD7_DROME", "id": "Q9VTD7-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MP----VMTKNG----------------------HSNSAYVADHPDKLELAEKG------------------QKNKAVVA------------------------------------------------KDPDYNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRK-KMPSMNYPMVAETAMGEGP-KCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS---------------------IDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFREPVTTEGKD-AFGK--PSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRL---GAQRNALFWEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWY-NTKGFAKVWLVLSNFVLIIVGILGLVIGTYTSLKEIVLTFSE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PEU1-1", "uniprot_id": "M9PEU1_DROME", "id": "M9PEU1-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSTPENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAAGSTLPLVISRKKGDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRR-KIPMMGFADVAEQAFLDGP-PALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETE---------------------LSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIYMFSDIPAPVERP-GIVS--VTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKGLEHKIR---PEKQN--ISEYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHE-DPGYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEFSSGH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX84-1", "uniprot_id": "Q9VX84_DROME", "id": "Q9VX84-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAPNQLEKNQTATVPRQETAE----GGSTGETAVGGAAAKVTK--------------------------------------------------------EQDHDAEYHPP-------TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFENGP-SKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYD----------------------IDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDG-LPEVEERALWTN-GSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNLG-DTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCG---IEGRS-LLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSE--LNKGPGIWICVKNLVILVLALLGFFTGSYESLKQIVKHFGEEEVH------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHT8-1", "uniprot_id": "M9PHT8_DROME", "id": "M9PHT8-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MPKRDLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEITGRQNDKSLEKNPERFTKN-----------------------------------------------------VTEKGADPENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNG----------------------IVISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTG-GAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNN---CTQKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQ--VPKALGVWSYIKNILILTVAVLGIVTGTYQSIVEIVKEFK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36062-1", "uniprot_id": "AVT3_YEAST", "id": "P36062-1", "name": "Vacuolar amino acid transporter 3", "aln": "MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDG-------YGDMGRILY-----------GPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLK------------------PGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFR---PSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASIL----SGTSRARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* .*.* : : .. .* . : . *: . : : * :* : ... . . : : : . . *:. . *: .:. :: : * . * : . . . : : : *: : : . : : : : . .: *:. * * :. . .. :: ", "identical_positions": 15, "similar_positions": 66, "identity": "1.93%" }, { "cls_id": "homologset.agr.SGD:S000001631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920L2-1", "uniprot_id": "SDHA_RAT", "id": "Q920L2-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "MAGVGAVSRLLRGRRLALAGATR--------GFHFSVGESKKASAKVSDAISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTIIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKH--VNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPPIKANAGEESVMNLDKLRFADGSVRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKVSQLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIEGQQKKPFAEHWRKHTLSYVDTKTGKVTLDYRPVIDKTLNEADCATVPPAIRSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2B3-1", "uniprot_id": "SDHA_MOUSE", "id": "Q8K2B3-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "MAGVGAVSRLLRGRRLALTGAWPGTLQKQTCGFHFSVGENKKASAKVSDAISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKH--VNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKANAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKISQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRVDEYDYSKPIQGQQKKPFGEHWRKHTLSYVDIKTGKVTLEYRPVIDKTLNEADCATVPPAIRSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31040-1", "uniprot_id": "SDHA_HUMAN", "id": "P31040-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRH--VNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVF3-1", "uniprot_id": "SDHA_DANRE", "id": "Q7ZVF3-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "MAAVCAASRVLG-TKILSCKSLPAVCQAN-RQLHFSIYG-KRGDAKISDGVSNQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEQDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENFGMPFSRTDDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECKGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTSTGDGNAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPNAKDLASRDVVSRSMTIEIREGRGVGPDKDHVHLQLHHLPPQQLAARLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITY--KDGQDHVVPGLYACGEAGCASVHGANRLGANSLLDLVVFGRACALTIAEIDTPGEKLSPLKPNAGEASVANLDKMRYANGSTRTSEIRLNMQKTMQSHAAVFRTGDVLKEGCVKMESVYKSMDDIKTFDRGIVWNTDLVETLELQNLMLNAVQTIVSAEARKESRGAHAREDFKDRVDEYDYSKPLQGQVKKPFEQHWRKHTLSYVDPETGKVTLEYRPVIDSSLDAEDCAAIPPAIRSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94523-1", "uniprot_id": "SDHA_DROME", "id": "Q94523-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "MSGIMRVPSILAKNAVASMQRAAAVGVQR--SYHITHGR-QQASAANPDKISKQYPVVDHAYDAIVVGAGGAGLRAAFGLVAEGFRTAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDWLGDQDAIHYMTREAPKAVIELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTGHSLLHTLYGQSLSYDCNYFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRAFFSCTSAHTCTGDGTAMVARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFMERYAPVAKDLASRDVVSRSMTIEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAGVDVTREPIPVLPTVHYNMGGVPTNYRGQVITID-KDGKDVIVPGLYAAGEAASSSVHGANRLGANSLLDLVVFGRACAKTIAELNKPGAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGVNKMKEIYKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVREDEYDFSKPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLDN-EVSTVPPAIRSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00711-1", "uniprot_id": "SDHA_YEAST", "id": "Q00711-1", "name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "aln": "---------MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADGKYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAALGNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIYQRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTHNGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGFPLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVVSRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIPIIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSLLDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNMKQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLTCASQTAVSAANRKESRGAHAREDYPNRDD-----------------EHWMKHTLSWQKDVAAPVTLKYRRVIDHTLDEKECPSVPPTVRAY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : .. . . :* ::** :*.:*:************* *:.** ::*********:*************.:*:*:**:**************:*****.:** :::***::*:*****::*:*********: ::***.**:* *.*******:*******::* :* :*:*******: .:** **:* ***::**:**::*::*******::********.****.**::* *:* **********:****:*******.***** *:*.:********** *****.******::*:** **** * .***::*** ****: * ********* ********:****::*********:**::.*:.: *:* ::*** *.***.. ********************** * :: : ** .: : *: *: ****:* *:*. *:::*:.*:::** ..:*** *.:* :: : :..:*. **.::**:***********: * * .* ************: * * :** *****: . :**.** *** :*: : .::**::*:*", "identical_positions": 362, "similar_positions": 148, "identity": "54.35%" }, { "cls_id": "homologset.agr.SGD:S000001632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923B1-1", "uniprot_id": "DBR1_MOUSE", "id": "Q923B1-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGSGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLQPAYWFSAHLHVKFAALMQH-------QATDKDQAGK-------------------------ETKFLALDKCLPHRDFLQVLEIEHDPSA-PEYLEYDVEWLTVLRATDDLINVTGGLWNMPEDNG--LHTRWDYSATEETMKEVMEKLNHDPKVPCNFTMTAACYDPS-----KPQTQVKLVHRINPQTTEFCAQLGITDINVMIQKAREEEHHQCG--EYEQQGDPGTEESEEDRSEYNTDTSALSS-INPDEIMLDEEEEEEEEEEEAVSAHSDMNTPSVEPAS---DQASDLSTS----FSDIRNLPSSMFVSSDDASRSPASGEGKC--GETVESGDEKDLAKFPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDGDASAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK59-1", "uniprot_id": "DBR1_HUMAN", "id": "Q9UK59-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQH-------QAKDKGQTAR-------------------------ATKFLALDKCLPHRDFLQILEIEHDPSA-PDYLEYDIEWLTILRATDDLINVTGRLWNMPENNG--LHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPS-----KPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEE-HHVCG--EYEEQDDVESNDSGEDQSEYNTDTSALSS-INPDEIMLDEEED----EDSIVSAHSGMNTPSVEPS----DQASEFSAS----FSDVRILPGSMIVSSDDTVDSTIDREGKP--GGTVESGNGEDLTKVPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDDDDDAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3E4-1", "uniprot_id": "DBR1_DANRE", "id": "Q7T3E4-1", "name": "Lariat debranching enzyme", "aln": "---MKVAVEGCCHGELDKIYESISYLENKDGVKVDLLLCCGDFQAVRNEGDMKCMAVPAKYRHMQTFYKYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVIRYKGVRIGGLSGIFKSHDFKKGHFEFPPYN----PETLRSVYHIRNIDVFKLKQIKMPIDIFMTHDWPRGIYHYGNTNALLRQKKFLRQEVESSTLGSPAAADLLEHLQPSYWFSAHLHVKFAALMQH-------EAKN-NTAPK-------------------------ITKFLSLDKCLPHRDFLQIVEVADRPGS-SEQLEYDPEWLAILKATDNLQKPTCNFWNPPQDNG--LHSRWDFSASEEAMMEVVSDLSGDLCIPENFSLTVPPYDPS-----QPQPHALPAYSTNPQTTELCATLNLTDIYILAGQSGQIYGERGGKGATEEEDEEDSTGSADEPSDFPSDTSGLSSSYNPDEITIEDEWEEE--EDGGVGCGEGKGMDAVVPEGQVGSQDSDRDSSPQRETAKRLILPAPCAKPKTEAPLHSLPRLSLPPPSACVSQGSSEEEGAFTAARVPKRTSGETTQSSAGQTGGTPQIKRRNQSIYTAVEDEESDS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSD7-1", "uniprot_id": "DBR1_DROME", "id": "Q9VSD7-1", "name": "Lariat debranching enzyme", "aln": "---MKIAVEGCAHGELERIYDTIEGIEKVGGTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDMCSFYKYYSGELVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIFKGHDFLRGHHEFPPYT----DSTCRSVYHVRQLEVFRLKQISGRVDIFLSHDWPTGIYEYGNKAQLLRKKPFFAADMESGKLGSQPLEELLKAVQPAYWFAAHLHCKFAALVPHNHSQKLGDAESSSSSSSSEDEDEEREKVKKAAPVPPPSKSVPVTKFLALDKCLPRRAFLQVVEVPSDPIEGTPRLEYDAEWLAILHSTNHLISVKENYYYLPGKKAGEFTERSNFTPTEEELEAVTAKF-QKLQVPENFERTVPAFDPAEQSDYKHMFVDQPKVQLNPQSNTFCATLGIDDPLCLVLLANGLDLPAVG---------------ATECKDRETKSSKLQA------------------------VEEDVAEPLVTPT------KRKLNLS----------LPAPTTAAADTTDENVIDLPEEE-----AEEAIIATETPHVEEPASVPASPNVKK-----------LKRRNQNIYQAQED------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24309-1", "uniprot_id": "DBR1_YEAST", "id": "P24309-1", "name": "Lariat debranching enzyme", "aln": "MTKLRIAVQGCCHGQLNQIYKEVSRIHAK--TPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKH-------NKRSHEPPNK-------------------------STSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEP---------DTSHASWKDENHRMFWDPEFINNLVICQKNKNLLS----NKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQ---------------------KDEVRQTKAFISKFMT--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::** **.**:*::**. : . :***: ****: *: *:: :*:* ** : * **..* *** *:*******: .:* **:**:** **:*:* :.*: .*:**..:***:* *: : : : . *.:**:* :: * :. :.*:::**** .: :*:. **: * *: :::...*** :**. ::* :*::**** :* * : * : . . *. :: : . : *** :: : . : .:. : . . *: : : . .. :. : : : : * : : ", "identical_positions": 92, "similar_positions": 111, "identity": "14.86%" }, { "cls_id": "homologset.agr.SGD:S000001633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4S1-1", "uniprot_id": "A0ABK0L4S1_RAT", "id": "A0ABK0L4S1-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "-MAER-EDD-HAEAWLQLKPVEPLPSQCCGSGCSPCVFDLYYRDLERWDTAQAKNDMSLLSGKQPPESQGCSTKLSPETFLAFHISTMEKVTRDTYLVRFTLPG-NCHLGLLPGQHLILRGVVD-DLEIQRAYTPISPATAQGYFDVLIKCYETGLMSRYVESWRPGDTAFWRGPFGSFLYEPKKYGELLMLAAGTGLAPMVPIVQSITDNEDDETFVTLVGCFKTFEDIYLKTFFQEQARFWNVRTFFVLSQEVSPDQLPWSYRDKTHFGRLGQELVDELVARCRRRPFTLVCGSPAFT-------------EDMARCLLSAGLTEDSYFLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AS42-1", "uniprot_id": "NB5R5_MOUSE", "id": "B1AS42-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "-MAET-EEEEDSEAWLRLKPVEPLPSQCCGSGCSPCVFDLYYRDLERWETARARNDRSLLSGKQPPESQSCSAKLSPETFLAFHISTMEKVTKDTYLVRFTLPG-NSRLGLRPGQHLILRGVVD-GLEIQRAYTPISPVTAEGYFDVLIKCYRTGLMSQYVESWRTGDTAFWRGPFGSFLYEPKKYGELLMLAAGTGLAPMVPILQSITDDEDDETFVTLVGCFKTFEGIYLKTFFQEQARFWNVQTFFVLSQEVSPEQLPWSYRDKTHFGRLGQELVAELVACCRRKPFTLVCGSPAFN-------------EDMARCLLSAGLTEDSYFLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IPT4-1", "uniprot_id": "NB5R5_HUMAN", "id": "Q6IPT4-1", "name": "NADH-cytochrome b5 reductase-like", "aln": "MMAEREEDDDTEEAWMQLRPTEPLPSQCCGSGCSPCVFDLYHRDLARWEAAQASKDRSLLRG---PESQSCPSKLNPETFVAFCIIAMDRLTKDTYRVRFALPG-NSQLGLRPGQHLILRGIVD-DLEIQRAYTPISPANAEGYFEVLIKCYQMGLMSRYVESWRVGDTAFWRGPFGDFFYKPNQYGELLLLAAGTGLAPMVPILQSITDNENDETFVTLVGCFKTFESIYLKTFLQEQARFWNVRTFFVLSQESSSEQLPWSYQEKTHFGHLGQDLIKELVSCCRRKPFALVCGSAEFT-------------KDIARCLLCAGLTEDSYFLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36060-1", "uniprot_id": "MCR1_YEAST", "id": "P36060-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "-MFSR----------LSRSHSKALP-IALGTVAIAAATAFYFANRNQHSFVFNESNK-VFKG--------------DDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNVVRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFKSITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPDK--FNVTYFVDDKQDDQDFDGEISF--ISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEKKSPKDQGELIGILNNLGYSKDQVFKF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : :.** . *: . ... :*. : : . . .: :: * :.:: : * ::. ::** . * ** :..:** .. *: : :. . :: *.***:* . :*:*::::* *. * *: :: . : .**. ::**: .: ::*::: .: :*.****: *: : : *.:: :*:* *.*: ** :.* *:. :: . : : * :: . .* .: : * :.:::: * *. :. .. :***.. * :: * * ::*. * *", "identical_positions": 60, "similar_positions": 121, "identity": "18.02%" }, { "cls_id": "homologset.agr.SGD:S000001634", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAT7-1", "uniprot_id": "NNRD_RAT", "id": "D4AAT7-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "MAVCPYG----AAAVVMALLSAAIAFHCSPLLAVLQRALSLHTAHATKDMDNLFQLVRNIVPALTSKKHKGQDG-RIGIVGGCQEYTGAPYFAGISALKVGADLTHVFCAREAAPVIKSYSPELIVHPVLDSS---------DAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKAR---DIPVVIDADGLWLIAQRP---ALVHGYQK--AVLTPNHVEFSRLWDAVLSSPMDTSNHSGSVLKLSQALGNITIVQKGEQD--LISNG-QQVLVCNQEGSSRRCGGQGDLLSGSLGVMAHWA----------------LRAGPEKTNGSSPLLVAAWGACTLTRECNHLAFQKYGRSTTTTDMIAEVGAAFSKLFTT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZ42-1", "uniprot_id": "NNRD_MOUSE", "id": "Q9CZ42-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "MAVHACG----AAAAVVALLSAAIALQWSPLYAVLQRALSLHTAHATKDMENLFQLVRNIVPALTSKKHKGQDG-RIGIVGGCQEYTGAPYFAGISALKVGADLTHVFCAREAAPVIKSYSPELIVHPVLDSS---------NAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKAR---DIPVVIDADGLWLVAQQP---ALIHSYHK--AILTPNHVEFSRLWEAVLSSPMDSNDLKGSTLKLSQALGNITVVQKGEQD--LISNG-QQVLVCNQEGSSRRCGGQGDLLSGSLGVMVHWA----------------LRAGPEKTNGSSPLLVAAWGACTLTRECNRQAFQKYGRSTTTTDMITEVGTAFSRLFTT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW45-1", "uniprot_id": "NNRD_HUMAN", "id": "Q8IW45-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "MVTRAGAGTAVAGAVVVALLSAALALYGPPLDAVLERAFSLRKAHSIKDMENTLQLVRNIIPPLSSTKHKGQDG-RIGVVGGCQEYTGAPYFAAISALKVGADLSHVFCASAAAPVIKAYSPELIVHPVLDSP---------NAVHEVEKWLPRLHALVVGPGLGRDDALLRNVQGILEVSKAR---DIPVVIDADGLWLVAQQP---ALIHGYRK--AVLTPNHVEFSRLYDAVLRGPMDSDDSHGSVLRLSQALGNVTVVQKGERD--ILSNG-QQVLVCSQEGSSRRCGGQGDLLSGSLGVLVHWA----------------LLAGPQKTNGSSPLLVAAFGACSLTRQCNHQAFQKHGRSTTTSDMIAEVGAAFSKLFET----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q575-1", "uniprot_id": "NNRD_DANRE", "id": "F1Q575-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "-------------MNLLKRATFIFSEQPLSLAIVIERSFSLGSS----GMDNVIPLVRNTIPPLTSKKHKGQDG-RIGIIGGCQEYTGAPFFAAISALKVGADLSHVFCTKDAAPVIKSYSPELIVHPVLDSP---------NAVEEIEKWLPRLHSVVVGPGLGREDMLLKNAKEIIERSKLR---GIPVIIDADGLWLVAKEP---SVIQGYQR--GILTPNFMEFTRLYEAMHHEPLDSSDHKRSAQQLSIALGHLTLVLKGEED--IITDG-KNILTCSQEGSGRRCGGQGDLLSGSLGAFAHWA----------------FSSPSDATKGMNPSLVAAFGATSLTRQCNRQAFHKHGRSTTTSDMIQEINSAFKKLFES----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVW8-1", "uniprot_id": "NNRD_DROME", "id": "Q9VVW8-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "------------------------------MAAVSDIPVHLP---------KLLALFKTVVPKLVNNKHKGQYG-RIGVIGGSLEYTGAPYFAAISSIRVGADLAHVFCHSNASAIIKSYSPDLIVHPVLDCV---------DAVERIAPWLERLHVVVIGPGLGREPGILKTASNVLKLCMDT---KKPVVIDADGLFLLNDNL---NLICGQPN--VILTPNVMEFQRLFG---------EDDQAARQKMSLLGAGVTVLEKGANDKIYLPHC-NEVHSMPSGGSGRRCGGQGDLLSGSLATFFSWS----------------LQSGEP-----NPALVAACASSYFVKKLNAAAFQKFGRSLLASDMVNQIPSVFQTEFENSDPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36059-1", "uniprot_id": "NNRD_YEAST", "id": "P36059-1", "name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase", "aln": "-----------------------------MLAELSHR-------------ELIKLAQKRCIPPLLPKFHKGQSGGRVCIIGGCEDYTGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVHPYLRMSNTKLDVDMDEQRKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLVIDADGLFLVTQDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIGKK----GDSHSEMGSLIAQELNCIVVEKGQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAFSRAMYDFKICEQEEKGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTTDLNDRVGEVFAKLFG-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : :* * . **** * *: ::**. :*****:*:. :: :*.**:**:* *..:**:*:*:*:*** * : ..: * *:* :*:******: :*.. ::. *::******:*: . :: . . :**** :** ** : : :: ** * .. ::: . **.:* ***** *:*::. : :: . :::. .. :.:: . .*: **: ::*: .: .* * ", "identical_positions": 78, "similar_positions": 92, "identity": "20.1%" }, { "cls_id": "homologset.agr.SGD:S000001635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16290-1", "uniprot_id": "PGAM2_RAT", "id": "P16290-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRYAG--LKPEELPTCESLKDTIARALPFWNEEIAPKIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70250-1", "uniprot_id": "PGAM2_MOUSE", "id": "O70250-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRYAG--LKPEELPTCESLKDTIARALPFWNEEIAPKIKAGQRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15259-1", "uniprot_id": "PGAM2_HUMAN", "id": "P15259-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAG--LKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBJ1-1", "uniprot_id": "PGAM1_MOUSE", "id": "Q9DBJ1-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD--LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25113-1", "uniprot_id": "PGAM1_RAT", "id": "P25113-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD--LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18669-1", "uniprot_id": "PGAM1_HUMAN", "id": "P18669-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD--LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N0Y7-1", "uniprot_id": "PGAM4_HUMAN", "id": "Q8N0Y7-1", "name": "Probable phosphoglycerate mutase 4", "aln": "--------------------------------------MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD--LTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVCKAIEAVAAQGKAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGB6-1", "uniprot_id": "Q9VGB6_DROME", "id": "Q9VGB6-1", "name": "Phosphoglycerate mutase", "aln": "MLALARNSWCGQLLCRVANIEARCPFSKSSSGGKQAEKKGKYRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAETAKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIVEDPRYKDQ-LKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISDKDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAMESVANQGKAK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAN7-1", "uniprot_id": "Q9VAN7_DROME", "id": "Q9VAN7-1", "name": "Phosphoglycerate mutase", "aln": "-------------------------------------MGGKYKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAETAAKYGEAQVQIWRRSFDTPPPPMEPGHPYYENIVKDPRYAEG-PKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSEDAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKAIEAVAAQGKAK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15327-1", "uniprot_id": "PMGE_MOUSE", "id": "P15327-1", "name": "Bisphosphoglycerate mutase", "aln": "--------------------------------------MSKHKLIILRHGEGQWNKENRFCSWVDQKLNNDGLEEARNCGRQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPYFHEIYSDRRYKVCDVPLDQLPRSESLKDVLERLLPYWKERIAPEILKGKSILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGNQEAIQAAIKKVDDQGKVKQGKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6G4-1", "uniprot_id": "Q6P6G4_RAT", "id": "Q6P6G4-1", "name": "Phosphoglycerate mutase", "aln": "--------------------------------------MSKHRLIILRHGEGQWNKENRFCSWVDQKLNSDGLEEARNCGRQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPFFHEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWKERISPEILKGKTVLISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAIRPHQFLGNQEAIQAAIKKVDDQGKVRQNK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07738-1", "uniprot_id": "PMGE_HUMAN", "id": "P07738-1", "name": "Bisphosphoglycerate mutase", "aln": "--------------------------------------MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00950-1", "uniprot_id": "PMG1_YEAST", "id": "P00950-1", "name": "Phosphoglycerate mutase 1", "aln": "----------------------------------------MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQ--KGDERYKY--VDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKPSKPSYYL-DPEAAAAGAAAVANQGKK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::::***:. ** :* * * * .*. * :** . :: *: ** .* * *. : :*: :********* * * :: : :.** :.. :***:: .***:: : : ** :* ** .: * **:*:: * .: * ::*:***** :.: **:: :*: * :.:***:*:: **::.::. . :* : *: . * *** ", "identical_positions": 72, "similar_positions": 72, "identity": "24.24%" }, { "cls_id": "homologset.agr.SGD:S000001637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZX7-1", "uniprot_id": "SRPRB_RAT", "id": "Q4FZX7-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASANTRRVGDG--AGGAFQPYLDSLRQELQQRDPTLLSVAVAVLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRLQFLDRFKSSAR---AVVFVVDSATFQREVKDVAEFLYQVL-IDSMALKNTPAFLVACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDAGSADVQDLEKWLAKIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47758-1", "uniprot_id": "SRPRB_MOUSE", "id": "P47758-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASANTRRVGDG--AGGAFQPYLDSLRQELQQRDPTLLSVAVALLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRFQLLDRFKSSAR---AVVFVVDSAAFQREVKDVAEFLYQVL-IDSMALKNSPSLLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDTGSADIQDLEKWLAKIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5M8-1", "uniprot_id": "SRPRB_HUMAN", "id": "Q9Y5M8-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASADSRRVADGGGAGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSAR---AIVFVVDSAAFQREVKDVAEFLYQVL-IDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSN9-1", "uniprot_id": "Q9VSN9_DROME", "id": "Q9VSN9-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MDKLNEN----------------ARQRKQIKLGEIDTGPIIVALLLGFIAVAIFVILRRRSAGRKDFLLTGLSESGKSAIFMQLIHGKFPATFTSIKENVGDYRTG---SASARLVDIPGHYRVRDKCLELYKHRAK---GIVFVVDSVTAHKDIRDVADFLYTIL-SDSATQPCS--VLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSRKLQSVG-----DEDGSKSITLGKPGRDFEFSHIAQNIQFAEASAK-------DTELDPLTDWLARLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36057-1", "uniprot_id": "SRPB_YEAST", "id": "P36057-1", "name": "Signal recognition particle receptor subunit beta", "aln": "------------------------MLSNTLIIACLLVIGTTIALIAVQKASSKTGIK--QKSYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQEP----LSAADYDGSGVTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLEASVVAFEGSIN-------KRKISQWREWIDEKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:: : : : : : .::.* :***: :: * . * .* . . . *:*:*** :* : : * *: .::*:***.. :.: .*:** :* . .*: ***.: *:... *:. **.*::.: *. .. :. . . : : *:*::: .: * * : . .:. .*: . ", "identical_positions": 39, "similar_positions": 80, "identity": "13.88%" }, { "cls_id": "homologset.agr.SGD:S000001638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z930-1", "uniprot_id": "D3Z930_RAT", "id": "D3Z930-1", "name": "Ribosome assembly protein METTL17, mitochondrial", "aln": "MATARASRFLLLFCRSCRSL-RGPQSRAFAALVPGVSQVDNRSDFLGKKPHRKHPGILHLPHVHLPQALTDAAQLLLLERPKRSVEKQVQALTNYLWSRHLPVEPEELQRRAAYLEKKFLEKQ-DSTQT------EEKLR----EAVLHALRKTTYHWQELSYNEELSLIYMAARLDGGFAAVFRAFHEIQARIPEFQPQTLMDFGSGTGSVAWAAHSTWG-------QSLREYVCVDRSAAMLGLAEKLLKGGSESGKPCIPG-VFFRQFLPVSPKVQFDVVVSAFALSELPS-----RADRTEVLQNLWRKTSHFLVLVENGTKAGHRLLMDARNLILG--------------------------DKEKSPLDLRPSFVFAPCPHELPCPQLNAAKS----------LACSFSQAYQPIPFH--WNKKPKEET---------------------------FSMVILARGSPKEANR---------------------------WPRITQPVLKRPRHVHCHLCCPDGHMQHAVVTARRHGRDLYRCARVSSWGDLLP-------------------------VIS--PSEFPPPSPAEEPPES------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2U7-1", "uniprot_id": "MET17_MOUSE", "id": "Q3U2U7-1", "name": "Ribosome assembly protein METTL17, mitochondrial", "aln": "MATARTPRFLLLFCRSCRSL-RGPQSRAYAALVPGVSQVDNGSDFLGKKPHRKHPGILHLPHVQLPQALADAAQLMLFERPMRSVEKQVQALTNYLWSRHLPVEPEELQRRAAYLEKKFLEKQ-DSAPT------EEKLR----EAVLHALRKTTYHWQELSYSEELSLIYMAARLDGGFAAVFRAFHEIQARIPEFRPQTLMDFGSGTGSVAWAAHRTWG-------QSLREYVCVDSSAAMLGLAEKLLKGGSESGKPCIPG-VFFRQFLPVSPKVQFDVVVSAYALSELPS-----RADRIEVIQNLWRKTSHFLVLVENGTKAGHRLLMDARNLVLG--------------------------EKEKSPLDLRPSFVFAPCPHELPCPQLNASKS----------LACSFSQAYHPIPFN--WNKKPKEEI---------------------------FSMVILARGSPKEANR---------------------------WPRITQPVLKRPRHVHCHLCCPDGHMQHAVVTARRHGRDLYRCARVSSWGDLLP-------------------------VIA--PSEFPPSSPDEEPPEN------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7H0-1", "uniprot_id": "MET17_HUMAN", "id": "Q9H7H0-1", "name": "Ribosome assembly protein METTL17, mitochondrial", "aln": "--MAAALKCLLTLGRWCPGLGVAPQARALAALVPGVTQVDNKSGFLQKRPHRQHPGILKLPHVRLPQALANGAQLLLLGSAGPTMENQVQTLTSYLWSRHLPVEPEELQRRARHLEKKFLENP-DLSQT------EEKLR----GAVLHALRKTTYHWQELSYTEGLSLVYMAARLDGGFAAVSRAFHEIRARNPAFQPQTLMDFGSGTGSVTWAAHSIWG-------QSLREYMCVDRSAAMLVLAEKLLKGGSESGEPYIPG-VFFRQFLPVSPKVQFDVVVSAFSLSELPS-----KADRTEVVQTLWRKTGHFLVLVENGTKAGHSLLMDARDLVLK--------------------------GKEKSPLDPRPGFVFAPCPHELPCPQLTN-------------LACSFSQAYHPIPFS--WNKKPKEEK---------------------------FSMVILARGSPEEAHR---------------------------WPRITQPVLKRPRHVHCHLCCPDGHMQHAVLTARRHGRDLYRCARVSSWGDLLP-------------------------VLT--PSAFPP-STAQDPSES------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IJY0-1", "uniprot_id": "A0A0R4IJY0_DANRE", "id": "A0A0R4IJY0-1", "name": "Ribosome assembly protein METTL17, mitochondrial", "aln": "-MHLLGSRVFVKCSRCHVALSLKEAIRCQSSAAP-LEQAD----YLNGAPHRKHPGVTNLKTVQLPEQLQLAAQSILQRADVKSLTERAQKLSNFLWSRKRVIESSQLREKAIILERKFLEEERNVSENDIDHNLEARIR----KKVLSELRRTTYHRAALRYNEDLGLVYMVARLAGGYAAVLRALNEIKKRDPLFVPYSLLDFGSGLGTGTWAAHRLWG-------DSLKEYVCVDSSGDMNTLAEQLLLEGSERNNPTIKQ-VYFRQFLPVSPKVQFDLVVAAFSLSELAT-----LDERLNVISTLWRKTNSYLVLVENGTKEGHQILMEARDAILK--------------------------REDEILHDPRRPSIFAPCTHELKCPKLIRQPV----------VPCNFFQFYYSLPLS--RSQERQQER---------------------------FSYLIVSRSDGEKAQKAEHW----------------------DMARVIAQVHRRPRHVQCQLCCVNGELKQLAVTARRHGKDMYRCARNSDWGDLLP-------------------------VFH--KEDEHTINDETE----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL60-1", "uniprot_id": "Q9VL60_DROME", "id": "Q9VL60-1", "name": "", "aln": "-MNFSLNFTTRNLVPRLHRFTSKIAVDVEPAVVSALEHAT--------LKPRKHPGVVRPNHVELPKQLNDTLKRIVGDHPVKKLIHDGQQLNAYIKSRHPPPTLEEIENKKRIVIEEVNTKMPLDRLATLDEDEAERWRRKRELEINKRLGQRIYAWKRIEYGAYESLVYAIARGAQEYAVLKRVLTELAQRDEQFRPRSFFDFGSGIGTGMWVASELWR-------EHIFEYYNVDRSREMNEISELILRDGHENKQIALRN-VFYRQFLPA-IETNYDLVIISHTLFELEN-----KEQREDVLRNLWRKCDGYLVIVEEGTRRGSELVNEARQFLLE--------------------------QEQE-------GHTVAPCPHDLVCPRLRDLADR---------TPCNFPISYAPLRLGSDFLADRHTSL---------------------------YSYAILKKGSQSDSSSS--------------------------WPRIVRPTLVRSKHAICRLCTEKGTLQEVIFTKSKHGKSAYSCAKVSRWGDRLP-------------------------MSLGQPQIKQESIESEEPPVLA-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36056-1", "uniprot_id": "RT22_YEAST", "id": "P36056-1", "name": "Ribosome assembly protein RSM22, mitochondrial", "aln": "----MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLPSYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPN---NLRRVATNYYKEIQEPNSLHRPCRTKMEVDAHIAS----IFLQNYGSIFQSLKELQKRVGPDNFKPQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILSRQLNEVVDTVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTHQLLHDGNQFPIQVDENIEHYLNILAPG-GHIVIIERGNPMGFEIIARARQITLRPENFPDEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHKEGKDLKFCNFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILNYSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIINDPVKRKGHVMMDLCAPSGELEKWTVSRS-FSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHKLEKERIKQLKKEERQKARKAMESYNELEDSLQFDDHQFSNFEVMKKLSTFHGNDFLQHVNRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .. . . . * : . : :. : : : ::.. .:. : . : . . :. . : * . * . * : : * .: . : : : . . . ::*::: :. * . . :. : .: .:*::*.*. * :: **: * : .***.*: ** *.* : :* *. :. .. .*: * *. ** .* ::. .: ..:. * *: * ** . : . : ", "identical_positions": 35, "similar_positions": 99, "identity": "5.46%" }, { "cls_id": "homologset.agr.SGD:S000001639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWY3-1", "uniprot_id": "RS27L_MOUSE", "id": "Q6ZWY3-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71UM5-1", "uniprot_id": "RS27L_HUMAN", "id": "Q71UM5-1", "name": "Ribosomal protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24051-1", "uniprot_id": "RS27L_RAT", "id": "P24051-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42677-1", "uniprot_id": "RS27_HUMAN", "id": "P42677-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWU9-1", "uniprot_id": "RS27_MOUSE", "id": "Q6ZWU9-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VBU9-1", "uniprot_id": "Q9VBU9_DROME", "id": "Q9VBU9-1", "name": "40S ribosomal protein S27", "aln": "MPLAKDLLHPLPAEEKRKHKLKRLVQHPNSYFMDVKCPGCYRITTVFSHAQGVVVCAGCATILCQPTGGRAKLTEGCSFRRKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35997-1", "uniprot_id": "RS27A_YEAST", "id": "P35997-1", "name": "Small ribosomal subunit protein eS27A", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:***** .* :*** * *** *.***:******* .********* .* * .*:*:** ****:*:*:** ***** ", "identical_positions": 54, "similar_positions": 14, "identity": "64.29%" }, { "cls_id": "homologset.agr.SGD:S000001640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q11011-1", "uniprot_id": "PSA_MOUSE", "id": "Q11011-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "------------------------------------------MWLAAAVPSLARRLLLLGPPPPPLLLLLSR--------------------------------------------------------------SSRRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPAEVSPINYSLCLKPDLLDFTFEGKLEAAAQVR-QATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYGGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGATLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELHNRYQGGFLIS-RLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKTSPPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M9V7-1", "uniprot_id": "F1M9V7_RAT", "id": "F1M9V7-1", "name": "Aminopeptidase", "aln": "------------------------------------------MWLAAAVPSLARRLLLLGSPPPPLLLLLSR--------------------------------------------------------------SSSRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPTEVSPINYSLCLKPDLLDFTFEGKLEAAAQVR-QATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGGFLIS-RLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKASPPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55786-1", "uniprot_id": "PSA_HUMAN", "id": "P55786-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "------------------------------------------MWLAAAAPSLARRLLFLGPPPPPLLLLVFS--------------------------------------------------------------RSSRRR-LHSLGLAA---------------------------------------------------------------MPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVR-QATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSKYTTP-SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGGFLIS-RLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NSE3-1", "uniprot_id": "A0A8M1NSE3_DANRE", "id": "A0A8M1NSE3-1", "name": "Aminopeptidase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPERRPFVRLPTDVYPVNYGLRLKPDLVDFTFEGKLEAAVEVT-QGTNQIVMNCADIDIITASFVPDGGEEINATGFNYQNEDEKVTLCFPSTLQKGS---GSLKIDFVGELNDKMKGFYRSKYSS--SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDRVALSNMNVVDRKPYAEDQSLVEVKFATTPIMSTYLVAFVIGEYDFVESQSSDGVTVRVYTPVGKAEQGKFALEVATKTLPFYKDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNSHPIEVDVGHPSEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGKPIAAVMNSWTKQMGFPIIVVDQEQHG-SDRVLKISQKKFCASGPRNDEDCPNWMVPISICTSEDPSCTKTKILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSSAMLESLLPGIRDLTLLPVDRLGLQNDLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSCNLGVLS--SLLSHTDFHEDIQEFIRDLFTPIGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFREHVEG-KQILSADLRSPVYLTVLKHGDSTTLDTMLKLHKQADMQEEKNRIERVLGAIPAPDLIQRVLNFALSEEVRPQDTVSVIGGVAGSSKQGRKAAWKFVKDNWEELHNRYQGGFLIS-RLIKLTVDGFAIDKMAAEVKSFFESHHAPAAERTVQQCCENILLNAAWLKRDADDIHQYLLQRKTPPV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRH1-1", "uniprot_id": "Q8IRH1_DROME", "id": "Q8IRH1-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "---MYKNALKGGIRTAKQAWKLKNELGKLNLDLAKANSDFEQHLCEAARYTQSFHFLARNTPRTPLLLLKTTGDNNSSPRIVANYYRTAPVNPPKQQNPKPSGAADKTTSVKHLFRAESGHLNALISSKQFVKVQKQFYRDFSSVSLGAPLKSSDAPLLGDLCSQYRAILAHTSADVIPGQDRHHPGCNYQQIRRAHTQLLSKEQQLEQERKMAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVK-EPTTQITLNALDIVLDSVELHFECS-KLKPEKIVYSAENETATLEFAQEIPAETQ--GVLHMSFTGELNDKMKGFYRSKYFGP-NGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDG--LRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENC-LWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLH--ILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNG-TELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVAINPK-GRDMAWEFFKENNKQLLERYQGGFLLS-RLIKYLIENFASEERAKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQRDREQLAIFLRDDQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32454-1", "uniprot_id": "APE2_YEAST", "id": "P32454-1", "name": "Aminopeptidase 2, mitochondrial", "aln": "MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPAGVSRSLRINVMWKQSKLTPPRFVKIMNR--------------------------------------------------------------RPLFTETSHACAKCQKTS----------------------------------------------------------QLLNKTPNREILPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKIG-----DVTSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGK---KVTLFNTTPKMSTYLVAFIVAELKYVESKNFR-IPVRVYATPGNEKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQHALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNG---KITFRQNRYLSTADVKPDEDKTIYPVFLALKTKN---GVDSSVVLSERSKTIELEDP---TFFKVNSEQSGIYITSYTDERWAKLG--QQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKSFVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQRLKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYEKVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMR-AHQEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKSTKGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** :* * :* * ::*:: *.* *. :: :.:* * : :.. .: . : . *:: .*: *.. . *.:.*.* ***:* ****::* ** :: ..**:*.*****.***:*** :**:* *:*: . . **** * .. . * ** *******.::.* .:** :. : ***::. *: ::* ** ::::*.*.:::. *.: *****:* :*: :*:************* . :*:* .*: * :* .* **:***********:** ******:*:::.: . .. **:.:* *:*: :* .**:* .****** * :..*:::*** ***.****::**: .::*:. * **:. ** :.: *: ***** .* .**.* : **. **:: ***:: *. : :: .: : : . .*: : * ::: *.: ..::.: . : : : :.*:* * * *:. .* . * **:** *: :: :* **.:.* ::. : ** .:.** : .: : *:. .: : :..* ::: : :***: : .:.. *: :: . : * * : .* .: :.* ::. : :* : *. : : .:: . ::*: * ** .*:.:.: : :. * ** : .: : * . *::.*.* .:* :* *: : ::. ..*: : *:: *: : . :::: *. :.* :* *::** : : :* : ", "identical_positions": 238, "similar_positions": 292, "identity": "21.7%" }, { "cls_id": "homologset.agr.SGD:S000001642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHG2-1", "uniprot_id": "RCAN2_MOUSE", "id": "Q9JHG2-1", "name": "Calcipressin-2", "aln": "MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTY--DECVTFQLFKSFRRVRINFSHPKSAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPP--VGWKPISDATP-------VLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDMEEEEDPK------TSPKPKIIQTRRPGLPPSVSN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CH27-1", "uniprot_id": "RCAN2_RAT", "id": "Q8CH27-1", "name": "Calcipressin-2", "aln": "MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTY--DECVTFQLFKSFRRVRINFSHPKAAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPP--VGWKPISDATP-------VLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDLEEEEDPK------TSPKPKIIQTRRPGLPPSVSN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14206-1", "uniprot_id": "RCAN2_HUMAN", "id": "Q14206-1", "name": "Calcipressin-2", "aln": "MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTY--DDCVTFQLFKSFRRVRINFSNPKSAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPP--VGWQPINDATP-------VLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDIEEEEDPK------TSPKPKIIQTRRPGLPPSVSN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IN33-1", "uniprot_id": "RCAN1_RAT", "id": "Q6IN33-1", "name": "Calcipressin-1", "aln": "MHFRDFNYNFSSLIACVANGDVFSESETRAKFESLFRTY--DKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSS----HLAPPNPDKQFLISPPASPP--VGWKQVEDATP-------VINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEEEEEEEEEMERMKRPKPKIIQTRRPEYTPIHLS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36054-1", "uniprot_id": "RCN1_YEAST", "id": "P36054-1", "name": "Calcipressin-like protein", "aln": "MGNIITDTIIITSDKCDIVDNDNVERIQVWLSKNILRKFQINENEPLQLIILKRFKRILLICPSHDISQHVMDASRALEMENFNFSYS-LQDGQRNLTKQYLKVPESEKMFLISPPASPPPEFDFSKCEDAPQRHIQSHIQQDQQQRLEASQLLPNNPDKNNNGTFTLLKSKVGAITIDRCPTNDGN--------GQMQLADHVKTAFPPKSIFDTDDDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : * : : :.::*.: :. .:* : : ** : * :: . : ::::: :: . :* *:. * ******:*** ..:. .**. : : ::* *.: : : .* : . * . * :: : : :: : :. .* ", "identical_positions": 27, "similar_positions": 62, "identity": "12.27%" }, { "cls_id": "homologset.agr.SGD:S000001643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60002-1", "uniprot_id": "ELOF1_HUMAN", "id": "P60002-1", "name": "Transcription elongation factor 1 homolog", "aln": "MGRRKSKRKPPPKKKMTGTLETQFTCPFCNHEKSCDVKMDRARNTGVISCTVCLEEFQTPITYLSEPVDVYSDWIDACEAANQ---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60003-1", "uniprot_id": "ELOF1_MOUSE", "id": "P60003-1", "name": "Transcription elongation factor 1 homolog", "aln": "MGRRKSKRKPPPKKKMTGTLETQFTCPFCNHEKSCDVKMDRARNTGVISCTVCLEEFQTPITYLSEPVDVYSDWIDACEAANQ---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEE9-1", "uniprot_id": "D4AEE9_RAT", "id": "D4AEE9-1", "name": "Transcription elongation factor 1 homolog", "aln": "MGRRKSKRKPPPKKKMTGTLETQFTCPFCNHEKSCDVKMDRARNTGVISCTVCLEEFQTPITYLSEPVDVYSDWIDACEAANQ---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MQI6-1", "uniprot_id": "ELOF1_DROME", "id": "Q8MQI6-1", "name": "Transcription elongation factor 1 homolog", "aln": "MGRRKSKRKPPPKRKNIEPLDQQFNCPFCNHEKSCEVKMDKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDACETAN----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KUN6-1", "uniprot_id": "Q7KUN6_DROME", "id": "Q7KUN6-1", "name": "Transcription elongation factor 1 homolog", "aln": "MGRRKSKRKGAPRKKNIQPLPILFDCPFCNHKQSCEAKLDKAKKIGRITCTVCQEFFQTHINYLTEAIDVFNDWIDACEEEN----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36053-1", "uniprot_id": "ELF1_YEAST", "id": "P36053-1", "name": "Transcription elongation factor 1", "aln": "MGKRK-KSTRKPTKRLVQKLDTKFNCLFCNHEKSVSCTLDKKNSIGTLSCKICGQSFQTRINSLSQPVDVYSDWFDAVEEVNSGRGSDTDDGDEGSDSDYESDSEQDAKTQNDGEIDSDEEEVDSDEERIGQVKRGRGALVDSDDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:** * . * :: * * * ****::* . .:*: .. . ::* :* : *** *. *::.:**:.**.** * * ", "identical_positions": 30, "similar_positions": 25, "identity": "20.55%" }, { "cls_id": "homologset.agr.SGD:S000001644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS8-1", "uniprot_id": "MK07_MOUSE", "id": "Q9WVS8-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSGEPPGRVKAEPVHTAASVVAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG--QQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILKPTVPYGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPVCPDVEMPSPWAPSGDCAMESPPPALPPCSDPAPDTVDLTLQPAPPASELAPPKREGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGTLGGPSTDPLAGLVLSDNDRSLLERWTRMARPPAP----APAPAPAPAPAPSSAQPTSTPTGPVSQSTGP-LQPAGSIPGPASQPVCPPPGPVPQPAG-----PIPAPLQTAPSTSLLASQSLVPPSGLPGSGAPEVLPYFPSGPPPPDPGLTPQPSTSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLSDLPDLQEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C865-1", "uniprot_id": "MK07_RAT", "id": "P0C865-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSGEPPGRVKAEPVHTAASVVAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG--QQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILRPTVPYGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPVCPDVEMPSPWAPSGDCAMESPPPALPPCSGPAPDTVDLTLQPAPPASELAPPKREGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGTLGGPSTDPLAGLVLSDNDRSLLERWTRMARPPVP----APAPAPAPTPKPSSAQPTSPPNGPVSQSTAP-LQPAGSIPGPASQPVCPPPGPVPQPAG-----PVPAPLQTAPSTSLLASQSLVPPSGLPGSGAPEVLPYFPSGPPPPDPGLTPQPSTSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLSDLPDLQEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13164-1", "uniprot_id": "MK07_HUMAN", "id": "Q13164-1", "name": "Mitogen-activated protein kinase 7", "aln": "MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG--QQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36005-1", "uniprot_id": "KDX1_YEAST", "id": "P36005-1", "name": "Serine/threonine-protein kinase KDX1", "aln": "--------------------------------MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTFRFEFEHIESMAELG--------------NEVIKEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPSRKVLPSYSPEFS----YVSQLPSLTTTQPYQNLMGISSNSFQGVN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: *:*. * :...:.: .**.*::.::.*: :. :***:******. ..********:*:*:: * **: : * * * :..**: :***.** ***:*.* * *.: *:**:* .***:***:*:* ****.*****.:*:*** :**:: . . . :: *:. *::: **:***::*. :* *:*:*:**.***:.*:*.*: :* **:**.:*: *: :****. .:* :.:::* ** .: .:*:: ***: :**.** :**.*:*. **:. **.**:*: :** *:* .* .* * *:: * .* *:: : *: :: . . .*. .:. * . : . *. *. .* . :. *. : * :. .**.*: .:: ", "identical_positions": 150, "similar_positions": 152, "identity": "18.32%" }, { "cls_id": "homologset.agr.SGD:S000001648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCV7-1", "uniprot_id": "Q9VCV7_DROME", "id": "Q9VCV7-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "-----------------------------------------MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLADHCSAVP--------DLRELFVEQALVGISRA-CPPTVTRPGHIAIFGGFNEDPAATLT---WNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGG-APLRFET---FARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS---VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDS-RTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKR---SAPNPG-QNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQ------YEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARE------SNHPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRD--------LMCQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRA-FFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSHVVY--FSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQP----VCTYVYAACWSYLLFAFLSIPYSGT--KDLRR--RLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKKDKPTPRAPVQAVTNNANLAQDSQA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB32-1", "uniprot_id": "Q9VB32_DROME", "id": "Q9VB32-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "-----------------------------------------MWKLQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAATFLANNGSDVP--------DLKDIYRQQGRIGISRT-CAPTMTRPGHIAIFAGFHEDPAASLMHLCYNPGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGG-APLRFDS---YMERDLPEKLTCDKWAFDKVENFLRNVDNVREWRNYKP---AVFFVYLADMDIAAHRFKPLSKKFFAKLQYTQRGIRNTYELFERVFNDS-RTAYLMTSDHGMNNEGAHGSGSPLEVETPLFMWGAGVKR---DEIDAE-ANFPEKPN-----ISQVDQTQLAPLMSSLIGLPPPKNNLALMPVGYLNVSDEYQAVALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGVIDQYAAQFDILKSEGN------LTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIWFYCLLLQLTRL------SKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPVGMLIMAQAERPVRG----------YWIFHPLWNFGFILVPAVLIMSMTFIIRHLWVLYGISVLLNNRRA-LRKPSIKLFIWLSLALIVTAILFMEQRT----IKGLKTIPVKDYHVLY--VSMVLAIIRPLILGHRHDPRVWTFNSLTLVVGAFGVYQYKFYES----VSSYVYVVTWSFLFFAFLSIVYFAKSLPEARK--RLELITINMITVLSLLTNSWGCLNFQIAITEFIFGLQIYEET--------------KETKEIEDAKDEHTS--LQNLKGFYRYGYMILLYFYVSFFLAGHWISSFLFKPTTARLFYPHFSLYIAGSLVLLKIFIPSVIFICALYAMVPFVRKNARSILISIFMISNAMGLYQYYFIRNRGSWRKIRMFLDQILLTHAVNFMLLLGISLAKIFLANTTMERPGQKR---ARTTRSNLAAAETEP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGM0-1", "uniprot_id": "Q9VGM0_DROME", "id": "Q9VGM0-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "MKLALLQTFLWCFFSVVVNVSFVLYRRLTYRLVGKVQVLMELWKSKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLFSDNCSGAV--------YIRDIILRQGLVGISKT-SVPTLTRSAEVALFAGFNPMPSILPT------SNFDTIFNR----------------TLAFDKG-AFLRFS-------------------HLSDLRRRLTKRACLEKLWYANK---LVMLVNLAEVGGAS----PLDIGFQMKLHNTQRNIRDAYELIEATFNDS-KTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKH---VTENIT-SDFVLNNGVG-MQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQAKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGW------RSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQN------VMAPHYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNG----------GWIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRG-WLHPSPKFLAWLALVLLLGGFLWS--------QKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVAAIGIFLKEMGKP----VPLYLFAANWAYLIYAFASVPCSSR--TTPQS--RLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKF----------------KEADEDVKILTSS---KHLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIFFRRLNMNRCSDWRQEADEFESSYPPITTTAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z838-1", "uniprot_id": "A1Z838_DROME", "id": "A1Z838-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "-----------------------------------------MWIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFFEENCRYVP--------NLRKIFLREGVVGVSRT-RVPTETRPGHITLIAGLYEDPSAVLRGWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYN---HDLDFSPGYDAYEEDEWVFKRVKLLLQQKREALQRAQN---VVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVFPDK-RTAYLLTADHGMTDSGAHGSGSPHETDTPFMLWGAGASR---AVPKPGGRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKRE------YSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNR-----ASKVELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWEN-FQWKSRDFFSWLALVLILSCFPLLP----------LSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGIN----IPIPLKLASWLYLVYAFASILLSKE--SRLDL--RLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSAR---------------------------------AERSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVMLVIFYTAKQLLRVIPWEEIDFKMLPLRLIHWDVISAKHH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LNZ1-1", "uniprot_id": "A0ABK0LNZ1_RAT", "id": "A0ABK0LNZ1-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "---------------------------------------MLLFFALGLLVHFVFFASIFDIYFTSPLVHGMTPQVTP----LPPPAKRLVLFVADGLRADALYELDEDGNS-----RAPFIRNVIMHEGSWGVSHT-RVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASG-DHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFSIVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYEDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYEDEFLKEWRLENWKRQDINQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEK------FDDVVSLCEELIDLALRGLSYYHTYDRLFLGISVAVGFVGWTSYASLLIIKSHSD--IPRGTRREGKKPHHLLPCSFIVAGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLKEREVIQALVESLLA--FPLSRFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITCLSWAFFSLLLAVFPLMPVVG---RKPDLSLVMGAGLLVLLLSLAVLATLVKRKLNLVKDELLVLLLQVLSTVLSMYVVYSTHHSLLKKEGLPLLNQIVSWAT-LASSLVVPLLSPTALWQ----RLTSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIHVEQETLQQSG-----VSCKQKLASIQFTYNTDITQFRQLCLDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLVISDIMALHFFFLVKDSGSWLDIGTSEKWIGKVGQENVAKASLQ-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1S3-1", "uniprot_id": "PIGN_MOUSE", "id": "Q9R1S3-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "---------------------------------------MLLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTP----LPPPAKRLVLFVADGLRADTLYELDEDGNS-----RAPFIRNVIIHEGSWGVSHT-RVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASG-DHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEK------FDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSN--IPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLT--FPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVG---RKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSWAT-LASSLVAPLLSSTALSQ----RLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPG-----VSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLM---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95427-1", "uniprot_id": "PIGN_HUMAN", "id": "O95427-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "---------------------------------------MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTP----LPPPARRLVLFVADGLRADALYELDENGNS-----RAPFIRNIIMHEGSWGISHT-RVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASG-DHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRK------FDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSN--LIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLT--YPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVG---RKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWAT-LASSLVVPLLSSPVLFQ----RLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSG-----VCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXW2-1", "uniprot_id": "E7EXW2_DANRE", "id": "E7EXW2-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "-------------------------------------MKMVTFFVVGLIVHVVFFLCIFDIYFTSPLVHGMTPQRVS----LPPPAKRLVLFVADGLRADSLFKPDDSGTS-----RAPYLRSVIEEGGTWGVSHT-RVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESRYTWCWGSPDILPMFAKGATG-DHVYTHTYPPEREDFASTDASRLDTWVFDEVKDFLTAAKSNETLLKKLHEEQNVFFLHLLGIDTNGHAHRPMSKECLENIGLVDAGVADIVTVMDDFYGHDGKTAYVFTSDHGMTNWGSHGAGHPSETLTPLVVWGAGVQKAQWETSQKYEDNYLKEWGLESYRRVDVNQADIAPLMSSLIGIPFPLNSVGVLPLSYLNNSQHFKAESMYANAIQILEQFRVKLAQKKETTISFLFTPYQPLTDSKQVDFIRQARDLIQKGR------FDEAIVYCKDLIAQAMEGLSYYHTYDRLFLGSSVVLGFIGWTSYVVLYILKTHAS--LRKPPTNTSMVTERLLGWGFLCVGLLMALFLLVQSSPWSYYIYSLMPVAVWYAVLKEFKTLVGLVRSIPS--LPLTKCFGYFVLVAFGIELLVMSFFYRAMLSLGLVVLALWPVVSGFYTKAKFKSLSWTLSCLSLAVFPLLPVVG---REPNINYVISAGGLILFNSSSFLWSS-WRDSPLMRRDRQLFIFQMVQVALCAYTLTSTHSSLQLKQGLPIFNQLVSWST-LVSSFLIPLLSSTRLFH----RLLSILMSLTCVYLLLSTGHEALFPLMLSWLMLAWIHIEQEAMSRQG-----SSNRNELSCIDFAENIDITKVRQLRLDDIRKSYFFVFFIIIAFFGCGNIASINSFDPASVYCFLTVFNPFIMGGLLMWKVLIPFVIVMCTFESIQVSTQLSSRSLFLIVLVISDLMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLMLLSVMTHILTSKKILLGRSRKMHFR---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36051-1", "uniprot_id": "MCD4_YEAST", "id": "P36051-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "----------------------------------MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQST----PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHT-RMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHN-PFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKS-----FILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAFYPFICG--VRELSVNILWIITSVLLSTFTLFDAV----KIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTR---AIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMK------------------------TQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDKTKKTQ-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VGL9-1", "uniprot_id": "Q9VGL9_DROME", "id": "Q9VGL9-1", "name": "GPI ethanolamine phosphate transferase 1", "aln": "---------------------------------------MLDSTRSFVLFQLLLLFAVVLIYLRSTYPGSLEPQEVEHLK-EPPPADRLVVLVRDGLSAQSFLANRCTNVP--------LLRELFLHQGLVGISRPETITYHSISPYISLFSGFNEDAASVARGWLGTPASIDSIFDRCKRSFAWTTTELISRFPKIERPRELSFETYG-----EGVTKSCSEMEDFVCRSVQRFLGGGS--RLLLNTTG---VIFFIHMTGVEPSCES-----------LQRIQENVWNVYKSFEKTFPDQ-RTAYLFTSNLGDP---QTKSEYSLAVESPFFLWGSGVNH----IKSMPGRSFMANEAGLRLPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAMLINAKQLLAQARRLRELHPKRMPAFWLS------FQMMDNFVKESLALKKQRR------FRALLDYSCNYMPVLIKGMDYFKDYYRHVSITAVSFAGIAWIYCLRCHLTVGKKCRNLIEIQEVISSKRLVYARGFHRLLTGVLVIIMMLERIPLVVQAILLIPSLYWRTTLKILGERP------------KMVCRKSLMSTALLALICFGGFFRRYILAVGYLGFASYNNREA-FKRRGHQFYLWLLLLLGLTVVSALP-------------ESLGCSQPGALMFSIFLTVLRPLACGVYLNLLTWLSNIPVLLAALEYILIG--------WHPWIMYLVSWIYLGFLVLWQRRNLQ---------ASEVFFFDLSTLYTLTCTSYESVVIQMLAMELQLALRMKLKR--------------------------------NESIGPKTAAHYILVYSWYSLFIIGSFPAFDDFLDILHETCFG-YSPLTYGLVMVLKLILPWLLVLCIMAGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNVGPWRDILSRFAEFAVVHVFPLVWLLLWRLTQLKVGSKWMSQLPNELL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:.. : .:. : : * *.* **.::: :*: * : ::.: . . *:*:. . : . ::::.*: : :*:.*:. : :::: : : : : .. : .. :*::: *: * :*:. **:* . : :. .::.**: *:*: * . . :* :. . *. .:* * : . : : * : * : :: : : * :.* : . : : . * . : . . : * : : : . .: :. . .. ::* * : .:: ::::* :. . : :: : . : * : . . ", "identical_positions": 38, "similar_positions": 142, "identity": "3.73%" }, { "cls_id": "homologset.agr.SGD:S000001649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68182-1", "uniprot_id": "KAPCB_RAT", "id": "P68182-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------TAIAKKGSEVES--------------------------------------------------------------VKEFLAKAKE--DFLRKWENPPPS--------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIR--VSITEKCGKEFCEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68181-1", "uniprot_id": "KAPCB_MOUSE", "id": "P68181-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------TAIAKKGSEVES--------------------------------------------------------------VKEFLAKAKE--DFLRKWENPPPS--------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIR--VSITEKCGKEFCEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22694-1", "uniprot_id": "KAPCB_HUMAN", "id": "P22694-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------AATAKKGSEVES--------------------------------------------------------------VKEFLAKAKE--DFLKKWENPTQN--------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEDIR--VSITEKCAKEFGEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05132-1", "uniprot_id": "KAPCA_MOUSE", "id": "P05132-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------AAAAKKGSEQES--------------------------------------------------------------VKEFLAKAKE--DFLKKWETPSQN--------------------TAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIR--VSINEKCGKEFTEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27791-1", "uniprot_id": "KAPCA_RAT", "id": "P27791-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------AAAAKKGSEQES--------------------------------------------------------------VKEFLAKAKE--DFLKKWEDPSQN--------------------TAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIR--VSINEKCGKEFTEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17612-1", "uniprot_id": "KAPCA_HUMAN", "id": "P17612-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN-------AAAAKKGSEQES--------------------------------------------------------------VKEFLAKAKE--DFLKKWESPAQN--------------------TAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIR--VSINEKCGKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZU3-1", "uniprot_id": "A0A8M9PZU3_DANRE", "id": "A0A8M9PZU3-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MCDR------KSSRRHGGKRESRSSGESRSSGGSAEGGGGGGGGSGSGGGVEGPTLLV-------------------------DVKEFLAKAKE--DFLKKWENPAQN--------------------TASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCK-GPGDTSNFDDYDEEEIR--VSITEKCGKEFAEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GPM4-1", "uniprot_id": "A0AC58GPM4_DANRE", "id": "A0AC58GPM4-1", "name": "cAMP-dependent protein kinase", "aln": "---------------------------------------------------------------------------MDEISEEYFQRSGKHNRLAARRLLVQAPAGTVGISVRSLHVLLAFTRVSSGCSGFPHSPKTCGTGELARVMAQPKDPHFGHSSGTNSALQKLDTLASRFFYKCRKGNHDKGLENEGPHVSEHTVLWDT-------------------------AMKETLAKAKE--DFLNKWECQQKS--------------------TACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCR-GPGDTSNFDEYDEEVIR--VSVSEQCSKEFLDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22612-1", "uniprot_id": "KAPCG_HUMAN", "id": "P22612-1", "name": "cAMP-dependent protein kinase catalytic subunit gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGN--------APAKKDTEQEE-------------------------------------------------------------SVNEFLAKARG--DFLYRWGNPAQN--------------------TASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYAD--QPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYT-GPGDASNFDDYEEEELR--ISINEKCAKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12370-1", "uniprot_id": "KAPC1_DROME", "id": "P12370-1", "name": "cAMP-dependent protein kinase catalytic subunit 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGNN-----ATTSNKKVDAAET--------------------------------------------------------------VKEFLEQAKE--EFEDKWRRNPTN--------------------TAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCK-GPGDTSNFDDYEEEALR--ISSTEKCAKEFAEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16911-1", "uniprot_id": "KAPC2_DROME", "id": "P16911-1", "name": "cAMP-dependent protein kinase catalytic subunit 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MSQHT------SQYVFNS-KED--------------------------------------------------------------YNVILDNMSR--EFEERWNHQTQSP-------------------YTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTIS-GAEDLSNFENFEFKDRY--KSRINRHPELFANF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA47-1", "uniprot_id": "Q9VA47_DROME", "id": "Q9VA47-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MGPQPE----QAQMHFSP-KVD--------------------------------------------------------------YILILDKLRE--DFNKKFATNTPSP-------------------STGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNIS-NPEDISNFDKVSDKPRP--KAKTMRHEEAFADF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51817-1", "uniprot_id": "PRKX_HUMAN", "id": "P51817-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MEAPGL----AQAAAAESDSRK-----VAEETP--------------------------------------------------DGAPALCPSPE--ALSPEP-------------------------PVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDD--NPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIA-GDGDTSNFETYPENDWDTAAPVPQKDLEIFKNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16912-1", "uniprot_id": "KAPC3_DROME", "id": "P16912-1", "name": "cAMP-dependent protein kinase catalytic subunit 3", "aln": "MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGR----SSSNVASSESSDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSE--SIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDE--QPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVH-HDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05986-1", "uniprot_id": "KAPC_YEAST", "id": "P05986-1", "name": "cAMP-dependent protein kinase type 3", "aln": "-----------------------------------------------------------------------------------------------------------------------MYVDPMNNNEIRKLSITAKTETTPDNVGQDIP---VNAHSVHEECSSNTPVEING-----------------------------------------------------RNSGKLKEEASAGICLVKKPMLQYRDTSG-----------------KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNS--NTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..: .:* *:** * : : . . * * : ::: ** * .*: :* .* : : : ::::: : ***:*: :. :* . . **:*:: :.:*:* :::*******:::: *::::*****:* : * ******:*:.**:: : :. :****::*:*::*: * .** : : *.:* : : *: *: * :.* ** * *:* : ** * : : : .* * * .:*: : . : :*", "identical_positions": 76, "similar_positions": 94, "identity": "12.84%" }, { "cls_id": "homologset.agr.SGD:S000001655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M920-1", "uniprot_id": "Q5M920_RAT", "id": "Q5M920-1", "name": "", "aln": "----MDTPPLSDSDSGSDECLASDQELQDAFSRGLLKPGLNVVLEKPKKAVNDENG--------------------LKQCLAEFKRDLEWVERLDVT--LGPVP-------------------------------------EASETQS-TPQNK--------DQKKGVNPEDD------------------------------------------------------------------FQREMSFYRQAQAAVLAVLPRLHQLQVPTKRPTDYFAEMAKSDQQMQKIRQKLQTKQAAMEKSEKAKQLRALRKYGKKVQTEVLQKRQQEKAHMMNAIKKYQK----GFSDKLDFLEGDQKPVERGAKAGGAKGQQISKGPNAKRRYKNQKFGFGGKKKGSKWNTRESYDDVSSFRGKVAHGKGPRRPGKKGANKRPGKRTRQKLKSKTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D903-1", "uniprot_id": "EBP2_MOUSE", "id": "Q9D903-1", "name": "Probable rRNA-processing protein EBP2", "aln": "----MDTPPLSESDSESDACLASDQELQDAFSRGLLKPGLNVVLEKPKKAVNDVSG--------------------LKQCLAEFRRDLEWVERLDVT--LGPVP-------------------------------------EVSETQP-TPQNQ--------DQKKGVNPEDD------------------------------------------------------------------FQREMSFYRQAQAAVLAVLPRLHQLQVPTKRPTDYFAEMAKSDQQMQKIRQKLQTKQAAMEKSEKAKQLRALRKYGKKVQTEVLQKRQREKAHMMNAIKKYQK----GFSDKLDFLEGDQKPVERSAKAGG-KGQQMSKGPNAKRRYKNQKFGFGGKKKGSKWNTKESYDDVSSFRAKVAHGKGSRRPGKKGANKRPGKRARQKLKSKAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99848-1", "uniprot_id": "EBP2_HUMAN", "id": "Q99848-1", "name": "Probable rRNA-processing protein EBP2", "aln": "----MDTPPLSDSESESDESLVTDRELQDAFSRGLLKPGLNVVLEGPKKAVNDVNG--------------------LKQCLAEFKRDLEWVERLDVT--LGPVP-------------------------------------EIGGSEAPAPQNK--------DQK-AVDPEDD------------------------------------------------------------------FQREMSFYRQAQAAVLAVLPRLHQLKVPTKRPTDYFAEMAKSDLQMQKIRQKLQTKQAAMERSEKAKQLRALRKYGKKVQTEVLQKRQQEKAHMMNAIKKYQK----GFSDKLDFLEGDQKPLAQRKKAGA-KGQQMRKGPSAKRRYKNQKFGFGGKKKGSKWNTRESYDDVSSFRAKTAHGRGLKRPGKKGSNKRPGKRTREKMKNRTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9Z9-1", "uniprot_id": "EBP2_DROME", "id": "Q9V9Z9-1", "name": "Probable rRNA-processing protein EBP2 homolog", "aln": "----MSDFEMEDSASGYDSGDNSDAELQAAFERGDLKPGLNVEFNGQRDKVNDVTK--------------------LLAKTEAIKMQLPWLERLDMINTLAPLA-------------------------------------PELAVQLEKHEQKRANLFKGNAKLPYIRPEEDP-------------------------------------------------------------VLNDFKREMLFHRQAQSAVLEAIPRLHELGIKTRRPDDYFAEMAKSDEHMQKVRANLMAKQQGQAKSERIKQIREQRKMGKMLAKQTKVQREAEKKDMLDKLKKFRK----GKLKNLDFLE-DAKALESKQKQSA-----------ENRKKRNKKFGFGGKKKGLKRNTKSSSAGLD--GDKSSRRQRGVKAG-ASVNKRLGKSRRIKAKGRK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36049-1", "uniprot_id": "EBP2_YEAST", "id": "P36049-1", "name": "rRNA-processing protein EBP2", "aln": "MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRG--------RPNGKRAAKNAKYGQGGMKRFKRKNDATSSADVSGFSSRKMKG----------KTNRPGKSRRARRF----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . : : :*: .: * .: . ::. :: :* ::. * :. : ::: : *:* :**: *::*: *** . .*:.* : :** ******.*** :*:*:: :* : *. :: * :* ** : . . :*: ** . :: :*. :: . .: :* : : . :* :* *:* ** *: : * * .:. : : .:* ** * : ", "identical_positions": 52, "similar_positions": 85, "identity": "11.58%" }, { "cls_id": "homologset.agr.SGD:S000001656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LM66-1", "uniprot_id": "F1LM66_RAT", "id": "F1LM66-1", "name": "116 kDa U5 small nuclear ribonucleoprotein component", "aln": "-MDTDLYDEFGNYIGPELDSDEDDDE-LGRETKDLDE-DEDED--DVGEHDD-DHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKT-------KKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYD------QDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMY-STDENLILSPLLGNVCFSSSQYSICFTLGSFAK-IYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPSSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLD-ELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTG--GVDSDLGEAMSDCDPDGPLMCHTTKMYS--TDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEED---SQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNE---EAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVET--------SSLKCFAETPNKKNKITMIAEPLEKGLAEDIEN----------EVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEP-LHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRG-HVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHH--WQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLS-------EDVSISKFFDDPMLLELAKQDVVLNYPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08810-1", "uniprot_id": "U5S1_MOUSE", "id": "O08810-1", "name": "116 kDa U5 small nuclear ribonucleoprotein component", "aln": "-MDTDLYDEFGNYIGPELDSDEDDDE-LGRETKDLDE-DEDEDEDDVGEHED-DHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKT-------KKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYD------QDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMY-STDENLILSPLLGNVCFSSSQYSICFTLGSFAK-IYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPSSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLD-ELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTG--GVDSDLGEAMSDCDPDGPLMCHTTKMYS--TDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEED---SQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNE---EAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVET--------SSLKCFAETPNKKNKITMIAEPLEKGLAEDIEN----------EVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEP-LHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRG-HVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHH--WQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLS-------EDVSISKFFDDPMLLELAKQDVVLNYPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15029-1", "uniprot_id": "U5S1_HUMAN", "id": "Q15029-1", "name": "116 kDa U5 small nuclear ribonucleoprotein component", "aln": "-MDTDLYDEFGNYIGPELDSDEDDDE-LGRETKDLDEMDDDDDDDDVGDHDD-DHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKT-------KKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYD------QDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMY-STDENLILSPLLGNVCFSSSQYSICFTLGSFAK-IYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLD-ELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTG--GVDSDLGEAMSDCDPDGPLMCHTTKMYS--TDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEED---SQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNE---EAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVET--------SSLKCFAETPNKKNKITMIAEPLEKGLAEDIEN----------EVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEP-LHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRG-HVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHH--WQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLS-------EDVSISKFFDDPMLLELAKQDVVLNYPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAX8-1", "uniprot_id": "Q9VAX8_DROME", "id": "Q9VAX8-1", "name": "116 kDa U5 small nuclear ribonucleoprotein component", "aln": "-MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKK-------LKFQIKEQDMQETTYDMEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEE------RQLRYTDTLFTEQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAK-LYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLA-ELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYTG--PKEGDIYRDMISCNQYGTLMVHSSKMYP--NDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQDEED---SRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPE---DLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVET--------SSLKCFAETPNKKNKITMISEPLEKGLAEDIEN----------GTVCINWNKKRIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIANEA-LHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRG-HVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHH--WQIVPGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLS-------EDVSINKFFDDPMLLELARQDVLINYPL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36048-1", "uniprot_id": "SN114_YEAST", "id": "P36048-1", "name": "Pre-mRNA-splicing factor SNU114", "aln": "MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGNNNEIESRQ------LTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGN-------VFSPIDNNIIFASTKLGFTFTIKEFVSYYYAHSIPSSKIDDFTTRLWGSVYYHKGN-FRTKPFENVEKYPTFVEFILIPLYKIFSYALSMEKDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFDNKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSESRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKGISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCSNESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGIMDNPRKLSKILRTEYGWDSLASRNVWSFYNG----NVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPILLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGFETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRRRKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:***** ** : ..::::. : : . : : . : : . * ..*. : . ** :**.::: :::*. *:::**. * :: : * *: ::: .: : . * ** : * ** *** ::* *: ::* .: . : * * * * * :** .** . *:: * : ** ::*::*:****** **.:..: ** *::.**..*** : .*:*:*:::::. *: . ***:*****:***** *** **.**: ::*.: . :.**: .*: *:*: .: **: .*.. **.: . :*:.****.:*:: . :* . :****** *:**::: .:. . .* * :: :.:::* :: : :*:*: * : :: : :*:** .. . : . . .* :. : : . * ::*. . .: : * : : * : : : :**:: : * .: : .** ::.. *: ***:*:.. :*::*: . . * : :*:**.: * :::**.::*: * ****:**.*.*:.* ** : :***********.****:**:::*** *::*:**::**:..*.*: : .*:. :.* .*:: :**::. : :*:.. * * :::.::::.:*.** **:*.:*:* . *:*::****.*:. ** *:.*:*** *..:****.:* * .*::*:*. :..: :. .**** ::. * .:* * * *:** *:: . * :. * :: :*** :: : :.*:*: ::. :*.*:* ******* *:* .:. * * *: **** ***. .* *:* *:*:*::*******:* :. ::.*::. : :* .:.:: ", "identical_positions": 287, "similar_positions": 351, "identity": "27.86%" }, { "cls_id": "homologset.agr.SGD:S000001662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53565-1", "uniprot_id": "CUX1_RAT", "id": "P53565-1", "name": "Homeobox protein cut-like 1", "aln": "--------------------------MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKR--------------LIEQSREFKKNTPEDLRKQVAPLLKS----------FQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDLGQQLEIKVQRLH--------------------DIETENQKLRETLEEYNKEFAEVKNQE-------------------------------VTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQR------------------------------EAETLREQLSSANHSLQLAS-QIQKAPDV--AIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEDVKKELTTLKSMEFAPSEGAGTQDSTKPL--------------------------------------------------------------------------------------------------------------------EVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPPQLPRNTG-EQVSNTNGT---------------------HHFSPAGLSQDFFSSNLASPSLPLA--------STGKFALNSLLQR-QLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQSPDVNGMAPSPSQSESAGSIS-------------------------------------------------EGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQR----------------------GNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQA-------SSTASSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKPAPLSQPDLTILNPKLLSASPMSTVSTYP--------------PLAISLKKTPAAPEASTSALPSAPALKKEAQDAPTLDPPGSADATPGVLRPVKNELVRGSTWKDPWWNPVQPERRNLTTS-------EETKADETNASGKEK-----TGSSQPRAERSQLQGPSATAEYWKEWPNAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMAKP--AKPSVPPLTP----------------EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPTIETSKEGKPPEPSDPPTSDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGIDY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQ-GQAGASDSPSARSSR-----AAPSSEGDSCDG---------------VEAADTEEPGGNIVAT------------KSQGGPAEVTAAPADREEATQ--PAEKAKAQPLSSGTPGQ----DDGEDAGRSRPPPEGLADAPAPVPNLAAPAAGEDAATSATAPAMATEA---PGAARAGPAERSSALPSTSAPANAPARRPSSLQSLFGLPEAAG--ARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53564-1", "uniprot_id": "CUX1_MOUSE", "id": "P53564-1", "name": "Homeobox protein cut-like 1", "aln": "--------------------------MLCVAG-----------AKLKRELDATATVLANRQDESEQSRKR--------------LIEQSREFKKNTPEDLRKQVAPLLKS----------FQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDVGQQLEIKVQRLH--------------------DIETENQKLRETLEEYNKEFAEVKNQE-------------------------------VTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQR------------------------------EAETLREQLSSANHSLQLAS-QIQKAPDV--AIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEEVKKELNTLKSMEFAPSEGAGTQDSTKPL--------------------------------------------------------------------------------------------------------------------EVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPPQLPRNTG-EQVSNTNGT---------------------HHFSPAGLSQDFFSSNLASPSLPLA--------STGKFALNSLLQR-QLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQSPDVNGMAPSPSQSESAGSIS-------------------------------------------------EGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNRSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQT-------SSTSSSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKPAPLSQPDLTILTPKHLSASPMSTVSTYP--------------PLAISLKKTPAAPETSTAALPSAPALKKEAQDVPTLDPPGSADAAQGVLRPMKSELVRGSTWKDPWWSPIQPERRNLTSS-------EETKADETTASGKER-----AGSSQPRAERSQLQGPSASAEYWKEWPSAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMAKP--AKPSVPPLTP----------------EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVASLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPAIETSKEGKPPEPSDPPASDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGIDY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQ-GQAGASDSPSARSSR-----AAPSSEGDSCDG---------------VEATDAEEPGGNIVAT------------KSQGGLAEVAAAPADREEATQ--PAEKAKAQPLCSGTPGQ----DDGEDASRPRPLPEGLADAPAPVPSLAAPAAGEDAATSATAPATATEA---PGAARAGPAERSSALPSTSAPANAPARRPSSLQSLFGLPEAAG--ARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39880-1", "uniprot_id": "CUX1_HUMAN", "id": "P39880-1", "name": "Homeobox protein cut-like 1", "aln": "--------------------------MLCVAG-----------ARLKRELDATATVLANRQDESEQSRKR--------------LIEQSREFKKNTPEDLRKQVAPLLKS----------FQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQRLH--------------------DIETENQKLRETLEEYNKEFAEVKNQE-------------------------------VTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQR------------------------------EAETLREQLSSANHSLQLAS-QIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPL--------------------------------------------------------------------------------------------------------------------EVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNPG-EQASNTNGT---------------------HQFSPAGLSQDFFSSSLASPSLPLA--------STGKFALNSLLQR-QLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPDVNGMAPSPSQSESAGSVS-------------------------------------------------EGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQP-------SSASGSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYP--------------PLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASS-------EEAKAEETGG-GKEKGSGGSGGGSQPRAERSQLQGPSS-SEYWKEWPSAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMSKP--TKPSVPPLTP----------------EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGTEY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQ-GQAGASDSPSARSGR-----AAPSSEGDSCDG---------------VEATEGPGS-ADTEEP------------KSQG--------EAEREEVPR--PAEQTEPPP--SGTPGP----DDARDDDHEG----GPVEGPGPLP---SPASATATAAPAAPEDAATSA---AAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLFGLPEAAG--ARDSRDNPLRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70298-1", "uniprot_id": "CUX2_MOUSE", "id": "P70298-1", "name": "Homeobox protein cut-like 2", "aln": "------------------------------------------------------------------------------------------------------MVAPVLKS----------FQAEVVALSKRSREAEAAFLSVYKQLIEAPDPVPSFEVARTLDDRLQRP---------------------SFDPSGQRLQDVHIAWKRCPEPPSAREQNEG----------------------------TCPTGHTPANGNHLPG-PEDTLVTDT---LLQKNEAERQKGLQEVHITLAARLGEAEEKIKVLHSALKATQTELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQR------------------------------EVESLREQLASVNSSIRLACCSPQGPSGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLASSTCSLPQTLAKPD--------------------------------------------------------------------------------------------------------------------DPLLVAKDVFFPTQKFLLEKPALLASPEEDPSEDDSIKGSLGTEPPYPP--QLPPPPGPEDPLSPSPA---------------------QPLLGPSLGPDGPRTFSLSPFPSLA--------PGERLAGDSLLSKHMMGPAAFKGETGNLLAFPPTFYGGAKPPSAPAASVPCPEPTGA-PEAVDG-----AGP---------------------------------------------------EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGESKNSPASVSIPNGTASSSTSED----------------------------AIKNILEQARREMQAQQQALLEMES------------GPRGRSVPPSPPERPSP--------------ATASQNGALTCVKQEDGGGGSGSSS----TVQAP-LAVLSPAAFVQRIIRKVKSEIGDAG-YFDHHWA---SDR-GLLSR-------PYASVSPSLSSSSS-----YSGQPNGRAWPRGDEATIAPEDEAAMG-EDEAP--RVGELKAEAGA-----PEVGGGRLPYYPAYVPRTLKPTVPPLTP----------------EQYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSD--------------------------------------------------------------------------------QLGQGQGQAPTQQPS------------------ASQASPTEPTSSPSPPPSPTEPEK------TSQEPLGLSLESSKENQQPEGRASSSLGGKPFS-------------------SSQAAGGIQEMVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLSDPHNVEKLRDMKKLEKKAYLKRR------YGLIGTGSDSESPAAHSECPSPCLQPQELS-LMQAKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDDPDFDPSGGPNVLTPGHTHREPTPQSPDSETEDQKPPMKSLELQE--PEGPLQRAAPDRALVKIKQE---EGLEVDGDSQPQDVGDPDRGQDGPKEEHTH--PLGNSDLSELAPGPFLSGTPNPDCPSLHNPQEKGTGEQVHSEPLSFKSTSESSCCSLEGPPNSPSVISS---PDLTTCVSPAPSSSAPISPSLPGAPPAKVPSTSPTGDTAAALHPSTKVNPNLQRRHEKMANLNSIIYRLERAANREEVLEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14529-1", "uniprot_id": "CUX2_HUMAN", "id": "O14529-1", "name": "Homeobox protein cut-like 2", "aln": "--------------------------MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKH--------------LIELRREFKKNVPEEIREMVAPVLKS----------FQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPP---------------------SFDPSGQPRRDLHTSWKRNPELLSPKEQREG----------------------------TSPAGPTLTEGSRLPGIPGKALLTET---LLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQR------------------------------EVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPE--------------------------------------------------------------------------------------------------------------------DSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPG---------------------QPLLGPSLGPDGTRTFSLSPFPSLA--------SGERL---------MMPPAAFKGEAGGLLVFPPAFYG-AKPPTAPATPAPGPEPLGG-PEPADGGGGGAAGPGA-------------------------------------------------EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSVAPLSIANGTTPASTSED----------------------------AIKSILEQARREMQAQQQALLEMEV------------APRGRSVPPSPPERPSL--------------ATASQNGAPALVKQEEGSGGP---------AQAP-LPVLSPAAFVQSIIRKVKSEIGDAG-YFDHHWA---SDR-GLLSR-------PYASVSPSLSSSSSS---GYSGQPNGRAWPRGDEAPVPPEDEAAAGAEDEPP--RTGELKAEGAT-----AEAG-ARLPYYPAYVPRTLKPTVPPLTP----------------EQYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSD--------------------------------------------------------------------------------QLGQAVG----QQPG------------------ASQASPTEPRSSPSPPPSPTEPEK------SSQEPLSLSLESSKENQQPEGRSSSSLSGKMYS-------------------GSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRR------YGLISTGSDSESPATRSECPSPCLQPQDLS-LLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPD--PPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASS---PGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G8V1-1", "uniprot_id": "A0AC58G8V1_DANRE", "id": "A0AC58G8V1-1", "name": "Homeobox protein cut-like", "aln": "----------------------MCCLLRLLSLSLSLSLSPSPMTVAERELNSVAAQLAGRQEESEDSHKH--------------LVELSREFKKNVPEDVLEMVSPVLKS----------FQAQVVALSQRSKEAESAFLAIYKQLIEAPDPAPLLEATQQRLAELQRS---------------------APE-GDALITEVSDRWRRRLECLDKAEHTEEE------------------------GPVTVETGEVSTQKPHMMTPNSTQTVQDGDAPLQNHQEPLQGEEEDQSDAPLPVRLDQAELRIKALQSSLSTARTELQELRCKYDQEKAEKLEEMCALMANLEKANQRADAAQR------------------------------EVEKLREQLSGTQSTSKGTGPSEERPKEERE-----RDERLEALLFSKDREILRLLENVQRLQFTLQEVQDSSANQIAELERQLAYKSEAIETLETKLQSQIDYEEIKTELSILKAMKLASANGSSSQESGKTA--------------------------------------------------------------------------------------------------------------------EALLLDKEAFLPSHKFLVDKVKVLHNSDDGHSEKS--NDVSRPAGSYSS----PPGTLPIDGRTSSSP---------------------APPTSDTSTHTLPRPFSVSPFSGEK--------LQDQLLQK------QLLSPLFKKDGSSIMAFPTALYAAKAALLSANHSASIPITMET-GMPSDQSESGSSGGG--------------------------------------------------DDDQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNILALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIQSQRG-DCKSSLGCPSGRSSTGAGSSSDE----------------------------AIKSILEQARREMQAQQQALLEMEV------------CGRSSASERLSIHDPPK--------------SQASS--TPPFIKQEEGISVPQSLSNPTGSPQTP-LSVLSPAAFVQNIIRKVKSEIGEAGTYFDQHWS---VERSAAVMG-------PFTSVSPSLSSSSS------TSMP--RPWPRIENGDCPANGEDTSAPEDEPMLSRQVEIKVEPDASVSSEASCGGGRVSFYPTYIPRTLKPTVPPLTP----------------EQYEMYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLLD--------------------------------------------------------------------------------QLGHGLNQLP-NHNH------------------SQEKSPVTSRSSPSPPASPADAQSS-----TVLEPVSLALESSKENQQPQPPQPLEPHGVKSSVM--------------IPQQTHTPLGIQELVAMSPELDTYAITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVDKLRDVKKMEKKAYLKRR------YGLLSPGSDSDSPGAHSDCISPGLSALDLCPFSQAKKPRVVLAAEEKEALRKAYLQEPYPSQHTIEMLAAQLNLKTNTVINWFHNYRSRMRREVLMEGLQDN---DTDAEHNNYSPLASH------SPVSDREDRKQ----------------PPSVRNRSVSTIPHR----------FAIKQETTEPEDEELRLRQDKCF--SIG--AFKSEEPGRSLNLLPDGPQRNSSASHEGEELEKSPEDPVSFKASSEPSRSSLEVSLNSPSAASS---PGLMMSVSPVPSSSAPISPSPPNPPALEPPSLN------------AKLNKNTQRRNEKMANLNNIIHRLERAANREETLEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10180-1", "uniprot_id": "CUT_DROME", "id": "P10180-1", "name": "Homeobox protein cut", "aln": "MQPTLPQAAGTADMDLTAVQSINDWFFKKEQIYLLAQFWQQRATLAEKEVNTLKEQLSTGNPDSNLNSENSDTAAAAATAAAVAAVVAGATATNDIEDEQQQQLQQTASGGILESDSDKLLNSSIVAAAITLQQQNGSNLLANTNTPSPSPPLLSAEQQQQLQSSLQQSGGVGGACLNPKLFFNHAQQMMMMEAAAAAAAAALQQQQQQQSPLHSPANEVAIPTEQPAATVATGAAAAAAAAATPIATGNVKSGSTTSNANHTNSNNSHQDEEELDDEEEDEEEDEDEDDEEENASMQSNADDMELDAQQETRTEPSATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIKALLDELQRLR----AQEQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQQINEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDALSEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLPGLPAFQFAAAQVAAGGDGRGHYRFADSELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPKKDSG---------------LPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQREREQQQRLRHDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHVFEREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRSSLEHSAGSSSCSKDGERDDAYPSSLHGRKSEGGGTPAPPAPPSGPGTGAGAPPTAAPPTGGASSNSAAPSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQRPTKAVLPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYP--PYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNKPTDGGNDSDHEHAQLEIDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKLKVINEEKLRMVRVRRLSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSSSNTSSSTPAVTTAAATAAAGWNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34237-1", "uniprot_id": "CASP_YEAST", "id": "P34237-1", "name": "Protein CASP", "aln": "-------------------------MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRKS--------------LATETKKFKKLEPEEKLNNVNKIIKQ----------YQREIDNLTQRSKFSEKVLFDVYEKLSEAPDPQPLLQSSLEKLGKIDDSK--------------------ELKEKISYLEDKLAKYAD------------------------------------------YETLKSRLLDLEQSSAKTLAKRLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKN--IDIEGNGNEDGDQENNQKEVSTRIAEYNLVTQELETTQAR------------------------------IYQLEKRNEELSGALAKATSEAEKETELH---------AKELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSED---------------------------------------------------------------------------------------------------------------------------KNDNTFESSLLSANKKLQATLAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEAN-----------------------------------------------------------------------------EKLETDLEKVENVSPHFN--------------------------------------------------------------------------------------------ETASMMSGVTRQMNNRTSHKMSPTSSIIGIPED--GELSGNQSTILPIVTKQRDRFRSRNMDLEKQLRQGNSEKGKLKLEIS-------------------------KLKGDNTKLYERIRYLQSYNN---------------------NNAPVNQSTER---------------------------------IDVESQYSRVYDESLHPMAN-------------FRQNELNHYKNKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSALEKLFSSFAKVILQNKMTRMVFLFYCIGLHG----------------------LVFMMSMYVIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISGYMTPEVG------IVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .: : : : : . . . * : :: . : . : .: : .: . : . . * : . * ::: . ..: : . : . * : * * . :: : : *: : . . : :. :*. : : . . . . : : . . : :* : * . : :. : ::*:.:. .*: .. .. :. : :: : . : .: .. : :: : * : . . ..: :. : : . : : .: . : : : : : :* :** .: *.::: . :: ::. ::.. .*:. : * :. *** : ", "identical_positions": 22, "similar_positions": 148, "identity": "1.0%" }, { "cls_id": "homologset.agr.SGD:S000001663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPR4-1", "uniprot_id": "RL17_MOUSE", "id": "Q9CPR4-1", "name": "Large ribosomal subunit protein uL22", "aln": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQK-KLKKQK-LMARE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24049-1", "uniprot_id": "RL17_RAT", "id": "P24049-1", "name": "Large ribosomal subunit protein uL22", "aln": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQK-KLKKQK-LMARE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18621-1", "uniprot_id": "RL17_HUMAN", "id": "P18621-1", "name": "Large ribosomal subunit protein uL22", "aln": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQK-KLKKQK-LMARE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3W8-1", "uniprot_id": "RL17_DROME", "id": "Q9W3W8-1", "name": "Large ribosomal subunit protein uL22", "aln": "MGRYSRESDNVAKSCKARGPNLRVHFKNTHETAQAIKRMPLRRAQRYLKAVIDQKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAEANADCKGLDADRLVVHHIQVNRAQCLRRRTYRAHGRINPYMSSPCHVEVILTEKEELVSKATDDEPAKKKLSKK-KLQRQKEKMLRSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05740-1", "uniprot_id": "RL17A_YEAST", "id": "P05740-1", "name": "Large ribosomal subunit protein uL22A", "aln": "MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRIAA---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **. . * :**..:**. *** ****:******: : :* :**: * ::..:****:*..:** **.*:: *:.*** **.:*: :*:** :**: ****. * : *****:* ************ * ***.*:*:::****: *.*. :. : . :: :: ** ", "identical_positions": 84, "similar_positions": 53, "identity": "44.92%" }, { "cls_id": "homologset.agr.SGD:S000001664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0M1-1", "uniprot_id": "KPRA_MOUSE", "id": "Q9D0M1-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "aln": "--------------------MN-AARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMR-KRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGE--------AQCTELDMDDGR------HSPP------------------------------------------MVKN-ATVHP------------------GLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKE-RGAYKIYVMATHGILSAEAPRLIEES-PIDEVVVTNTVPHELQKLQCP-KIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14558-1", "uniprot_id": "KPRA_HUMAN", "id": "Q14558-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "aln": "--------------------MN-AARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMR-KRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGE--------AQCTELDMDDGR------HSPP------------------------------------------MVKN-ATVHP------------------GLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKE-RGAYKIYVMATHGILSAEAPRLIEES-SVDEVVVTNTVPHEVQKLQCP-KIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63468-1", "uniprot_id": "KPRA_RAT", "id": "Q63468-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "aln": "--------------------MN-AARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMR-KRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGE--------AQCTELDMDDGR------HSPP------------------------------------------MVKN-ATVHP------------------GLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKE-RGAYKIYVMATHGILSAEAPRLIEES-PIDEVVVTNTVPHELQKLQCP-KIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R574-1", "uniprot_id": "KPRB_MOUSE", "id": "Q8R574-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 2", "aln": "-------MFCVAPP-ELETKMN-ITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTISKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMR-KRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGE--------AQDAESDLVDGR------HSPP------------------------------------------MVRSVAAIHP------------------SLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKE-RGAYKIFVMATHGLLSSDAPRLIEES-AIDEVVVTNTIPHEIQKLQCP-KIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08618-1", "uniprot_id": "KPRB_RAT", "id": "O08618-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 2", "aln": "-------MFCVAPP-ELETKMN-ITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMR-KRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGE--------AQDAESDLVDGR------HSPP------------------------------------------MVRSVAAIHP------------------SLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKE-RGAYKIFVMATHGLLSSDAPRLIEES-AIDEVVVTNTIPHEIQKLQCP-KIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60256-1", "uniprot_id": "KPRB_HUMAN", "id": "O60256-1", "name": "Phosphoribosyl pyrophosphate synthase-associated protein 2", "aln": "-------MFCVTPP-ELETKMN-ITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMR-KRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGE--------AQDAESDLVDGR------HSPP------------------------------------------MVRSVAAIHP------------------SLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKE-RGAYKIFVMATHGLLSSDAPRRIEES-AIDEVVVTNTIPHEVQKLQCP-KIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA53-1", "uniprot_id": "Q9VA53_DROME", "id": "Q9VA53-1", "name": "Ribose-phosphate pyrophosphokinase N-terminal domain-containing protein", "aln": "MLLQRNKLGSVRPPKRCRSDMDNTSTSDIVIINGNSHP---DLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSARSIVGVIPYLPYSKQCKMR-KRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGE--------QKETDADEVDGR------YSPPPTSAYSNLLGNSVEMCLP-----------------------ATPRNSTPQHAPTSSARQ------RTTSVSVGVPEHIVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKE-NGACKIYVLATHGLLSSDAPRQLDES-PIDEIVVTNTIPHEIQKLQCH-KIKTIDISILIAEAIRRIHNKESMSYLFRNVTLED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32895-1", "uniprot_id": "KPR1_YEAST", "id": "P32895-1", "name": "Ribose-phosphate pyrophosphokinase 1", "aln": "--------------------MR-----KCKIFVGNSHP---ELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQSMLRKNRPIIRQGDHPNEEENIILSNGIQTARIRNGHVIGDDEADDDEDAILESDSELHSIDGLDSHGLGGTYDAVDSEDEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVLFDSLAAL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: .** . :*.: : :*:* : . : : .* ** *:* ***.:*:::**: . . * :*****:. * : ..*:.* .*** :*****.**: :**.*..::**.:: :* *:::**** .::**** ***** ..* * ::*:*.: :*.::*:*::.* :*:. : *: *::.:*:** : : : : . * . * .. : *. : : :*:**:* ** **::**:** :*::*** * : ** *::*:****:::.:. . :::* .:* :***** * . ::: *: *:*:* :::*.*** * **:: ** .: ", "identical_positions": 119, "similar_positions": 130, "identity": "26.1%" }, { "cls_id": "homologset.agr.SGD:S000001667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVM4-1", "uniprot_id": "AZIN2_MOUSE", "id": "Q8BVM4-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEGFSTRDLLEELTLGASQATSG---------------------------KVAAFFVADLGAVVRKHFCFLKHLPRVRPFYAVGCNSSLGVLKVLAELGLGFSCANKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKMVLCIATQDSHSLNHLSLRFGASLKS-CRHLLENAK-KSHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFQMGEELG--HTMNILDLGGGFPGLEGAKVRFEEMASVINSALDLYFPEGCGVDILAELGRYYVTSAFTVAVSIVAKREVLD---QASREEQTGAAPKSIVYYLDEGVYGVFNSVLFDN-TCPTP---------ALQKKPSAD-----------QPLYSSSLWGPAVEGCDCVAEGLWLPQ-LQVGDWLVFDNMGAYTVDTKSLLGGTQARRVTYAMSRLAWEALRGQLLPAEEDQDAEGVCKPLSCGWEITDTLCVGPVFTPASIM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A693-1", "uniprot_id": "AZIN2_RAT", "id": "D4A693-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEGFSTRDLLEELTLGASQATTG---------------------------KVAAFFVAD--AVVRKHFCFLKYLPRVRPFYAVRCNSSLGVLKVLAELGLGFSCASKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKSWGEVLTLDALGLHHTHRRVGCSLMF-QASVIASVA-QGYLELVCQPFHIGSGCPDPQAYAQSIADARLVFQMGAELG--HTMNILDLGGGFPGLEGAKVRFEEVTSVIGKNIPFYTPPPCHVPLRTHATKKMTSSDFCCRVHVTAKEKPLF---SPFLTEQTGAAPKSIVYHLDEGVYGVFNSVLFDN-TCPTP---------ALQKKPSAD-----------QPLYSSSLWGPAVDGCDCVAEGLWLPQ-LQVGDWLVFDNMGAYTVDTKSLLGGTQACRVTYAMSRLAWEALQGQLLPAEEDQDAEGVCKPLSCGWEITDSLCVGPVFTPASIM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A70-1", "uniprot_id": "AZIN2_HUMAN", "id": "Q96A70-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEGFSTRDLLKELTLGASQATTD---------------------------EVAAFFVADLGAIVRKHFCFLKCLPRVRPFYAVKCNSSPGVLKVLAQLGLGFSCANKAEMELVQHIGIPASKIICANPCKQIAQIKYAAKHGIQLLSFDNEMELAKVVKSHPSAKMVLCIATDDSHSLSCLSLKFGVSLKS-CRHLLENAK-KHHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFEMGTELG--HKMHVLDLGGGFPGTEGAKVRFEEIASVINSALDLYFPEGCGVDIFAELGRYYVTSAFTVAVSIIAKKEVLLD--QPGREEENGSTSKTIVYHLDEGVYGIFNSVLFDN-ICPTP---------ILQKKPSTE-----------QPLYSSSLWGPAVDGCDCVAEGLWLPQ-LHVGDWLVFDNMGAYTVGMGSPFWGTQACHITYAMSRVAWEALRRQLMAAEQEDDVEGVCKPLSCGWEITDTLCVGPVFTPASIM--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00860-1", "uniprot_id": "DCOR_MOUSE", "id": "P00860-1", "name": "Ornithine decarboxylase", "aln": "------------------MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDD-----------------------------KDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVG--FSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDH-AHVKA---------LLQKRPKPD-----------EKYYSSSIWGPTCDGLDRIVERCNLPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFPPEVEEQDDGTLPMSCAQESGMDRHPAACASARINV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09057-1", "uniprot_id": "DCOR_RAT", "id": "P09057-1", "name": "Ornithine decarboxylase", "aln": "------------------MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDD-----------------------------KDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVG--FSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDH-AHVKA---------LLQKRPKPD-----------EKYYSSSIWGPTCDGLDRIVERCSLPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11926-1", "uniprot_id": "DCOR_HUMAN", "id": "P11926-1", "name": "Ornithine decarboxylase", "aln": "------------------MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDD-----------------------------KDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRT-SRLLLERAK-ELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVG--FSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKE--QTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDH-AHVKP---------LLQKRPKPD-----------EKYYSSSIWGPTCDGLDRIVERCDLPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40807-1", "uniprot_id": "DCOR1_DROME", "id": "P40807-1", "name": "Ornithine decarboxylase 1", "aln": "---------------------MAAATPEIQFYERELNIR----RVIEECDLQRL-----------------------------DQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAK-SLELKVTGTSFHVGSGCSELQAYDRAIKKAKNLFKFGALLG--YDMDFLDIGGGFPGSD--DVKFEKIAESVNTSVQRHFPDER-VHIIAEPGRFFVAAACTLVCKIHAKREIR----------NEAGKLDTVMYYLNDGVYGSFNCILYDH-QVVIA-------EHYLDNAESLP-------------HLKSLIWGPSCDALDKISEDLHLPN-LNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLYFQAI--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40808-1", "uniprot_id": "DCOR2_DROME", "id": "P40808-1", "name": "Ornithine decarboxylase 2", "aln": "---------------------MVNGDLRIQYYDEELNIR----KVIEQADLEHL-----------------------------DQALNICDLSSLERKLRLWHKLMPRIEPHYAVKCNDDPVVVKFLADLGTGFDCASKNELKLVLGLGVSPERIIFAHPCRPASHLRYAKEQQVVNGTVDNEYEIYKLRKHYPDSNLIVRFKSEAKKALCPLGDKYGCDAEADAAALMLLAK-ALGLKVTGTSFHVGSGCSEVEAYDRAIEKAENIFKVGEMIG--HKMELLDVGGGFPGID--DEMFEEIAQSVNTSVELRFPDKR-IRIISEPGRFFVEAAYTLICKVHAKREVR----------SKDGKLDTMMYYLNDGIFGAFAGMFYYP-EEVAP-------ELYLDEAESLP-------------KLKSVIWGPSCDAMDKIS-DLLLPN-LNPGDLLGFRNMGAYTMPIASPFNGFDVPETRFFKAK--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08432-1", "uniprot_id": "DCOR_YEAST", "id": "P08432-1", "name": "Ornithine decarboxylase", "aln": "MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMEN-VDVLLKAIK-ELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQ-----FESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLS----------ENE-----AMIYTNDGVYGNMNCILFDH-QEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "F1LVE6-1", "uniprot_id": "F1LVE6_RAT", "id": "F1LVE6-1", "name": "Antizyme inhibitor 2", "aln": "------MTTPSEGRREPLGVTESLWPSEPITLGPETSARQLVLKKIQDLSISGH-----------------------------QDPFMVADLDVLASRHQTFLQALPRVWPFYAVKCNNRPSLLLVLAALGTGFDCASQGELEQVLGLGVAPSRIIFANPCKAVSHIQYAARCGVQLLTFDSEEELTKLARHHPGARLILRIQTLGGRSTFPLHTKFGARLLA-CGRLLQVAR-ELGLAVVGASFHVGSDCHTPQSYRQAIADCHRVFEMGCKAG--HQMSLLDLGGGFPGIEGSEAKFEEMARVVNAALAQYFPEGTGVEVIAEPGRFYAESVCTAAVNIIAKKASL-----------EPGGHRKLAYYLNEGHYGAFRIFLRDP-VPRIP--------IVVKELPSDP------------HLFPCTLYGPTCDAFDRLFSTEVQLPELDVGDWLVFPDMGAYRSTMSSTFNGFPITTVYDAMSPQLRSLLETVP----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q801V3-1", "uniprot_id": "Q801V3_DANRE", "id": "Q801V3-1", "name": "", "aln": "-----------------MKGFVDAPNYFIELLEGGTTLENVIDNHIYEQNLAEK------------------------------NAFVVADLGALMRQHVVWKTTMPLVRPFYPVSCNSSPVVIELLSALGVGFVCANKAETTLVLSHDVPPENIILSGVCKQLSLIKHAAKTGINFLLCENEAELRKIARAHPEAKLLLQVSTE--AQIEEASVTIGCSLKG-CRHLLELAK-ELNVSVAGVTFQVPASCKDPQAYTHALSDARCIFDMGKELG--FDMNILDIGGGFSGSE---FQLKQVHSVIRPLLEAYFPSESGVSIIAEPGNFFVFSCFTLAVNVIGKKAAYRNLHTSTHDKLTSSDAPEFVYYMNDGVYGSFMGRLFGN-IISTP--------SVHKMSLTLDE-----------PVFSSSLWGPSCDPLDQVVERCLLPE-LAVGDWLVFSNMGASGQEGPATFSDTDQPPVYYTISTDDWFEMQEAGISLDDTMKNLSLVQFGL-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N598-1", "uniprot_id": "A0A8M1N598_DANRE", "id": "A0A8M1N598-1", "name": "", "aln": "---------------MSMKGSLDELHYSVELLEGSAALRDVIDKHIYDQTFAQK------------------------------SAFFAADLGVIVQQQARWRNKMDQIRPFYTVKSNSSPVVVELLASLGTGFICSNKHELDLVKGFGVSSQDIILGGTCKQLSHIKYAAKHNIPLLVCDNEAEMRKIARCHPKAKVLLLLTSESCCEKEEMAIPFGSTLKD-CRRLLECAAGELNLQVTGVKFNIPSCCQEVEKFSRAVSEARCVFDMGEELG--FEMNILDIGGGFDGSE---EQLDKVNQMLKPMLDMYFPRSTGLSIIAEPGAYYVSSAFTLAVNIIDKKTVARDCSAQPHDALSANDEPEFLYHINDGVYGSFASKLLCEDSIATP--------LAHKH-VSADE-----------PLFSSSLWGPSEDDLDLVMERCLLPE-LSVGDWLLFRNAGASALGSAFSHGDQHKPPVFYSITEYDWQEIHNSGVTVDVRMKNFSLVPCCLQPNMSGASISTPA----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14977-1", "uniprot_id": "AZIN1_HUMAN", "id": "O14977-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHTLTGK------------------------------NAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIG--FTMNMLDIGGGFTGTE---FQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEK-TGSDEPAFMYYMNDGVYGSFASKLSED-LNTIP--------EVHKK-YKEDE-----------PLFTSSLWGPSCDELDQIVESCLLPE-LNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQE-DSFSAEA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63764-1", "uniprot_id": "AZIN1_RAT", "id": "Q63764-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHTLTGK------------------------------NAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFG--FTMNMLDIGGGFTGTE---IQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEK-NGSDEPAFVYYMNDGVYGSFASKLSED-LNTVP--------EVHKK-YKEDE-----------PLFTSSLWGPSCDELDQIVESCLLPE-LSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQE-DNFSTEA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABJ3HKJ7-1", "uniprot_id": "A0ABJ3HKJ7_MOUSE", "id": "A0ABJ3HKJ7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MP---P------KKRRRFTRLFGPLSHG-ELSDR----------------VYN----------YP--EGLGEVLYREQFDFNAEPPWEPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :. . . : : : :. : . :. * ", "identical_positions": 2, "similar_positions": 16, "identity": "0.37%" }, { "cls_id": "homologset.agr.SGD:S000001671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY44-1", "uniprot_id": "ABCD2_RAT", "id": "Q9QY44-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "MIHMLNAAAYR---------VKWTRSGAAKRAACLVAAAYALKTLYPILGRRLKQPGHRKAKA---------------EDYPPAENRERLHCTEIICKKPA-----PGLNADFFKQLLELRKILFPKLVTTETGWLCLHSVALIS--RTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLV-KWLMIAVPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGTLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSGCGLIMVAIPIITATGFADGDLEDGPKQAM-------VSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRT--VTQEPENNSKSRGGLELPLSDTLAIKGTVIDVDHGILCENVPIITPAGEVVASSLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEG--------VLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSVDDMHEK-----GYTDRDLEHILHSVHLYHIVQR-------------------------------EGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAE--------DTS--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61285-1", "uniprot_id": "ABCD2_MOUSE", "id": "Q61285-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "MIHMLNAAAYR---------VKWTRSGAAKRAACLVAAAYALKTLYPIIGKRLKQPGHRKAKA---------------EAYSPAENREILHCTEIICKKPA-----PGLNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALIS--RTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLI-KWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGFADGDLEDGPKQAM-------VSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRT--VTQEPENHSKRGGNLELPLSDTLAIKGTVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEG--------VLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSADDMREK-----GYTDQDLERILHSVHLYHIVQR-------------------------------EGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAE--------KTS--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBJ2-1", "uniprot_id": "ABCD2_HUMAN", "id": "Q9UBJ2-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "MTHMLNAAADR---------VKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKA---------------AAYPAAENTEILHCTETICEKPS-----PGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALIS--RTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLI-KWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADG--EDGQKQVM-------VSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTA-VIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEG--------VLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSVDDMHDK-----GYTDQDLERILHNVHLYHIVQR-------------------------------EGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNED--------ETS--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48410-1", "uniprot_id": "ABCD1_MOUSE", "id": "P48410-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "---MPVLSTP----------RPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVP----------------------AGEPTQEASGATATKA-------GMNRVFLQRLLALLRLLFPRVLCRETGLLALHSAALVS--RTFLSVYVARLDGRLARCIVRKDPRAFSWQLL-QWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVKHCRFKRTG-DLEEAQAGPGVMVQSGVHVEGPLKIQGQVVDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSG--------VLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSAEDMRRK-----GCSEQQLEAILGIVHLRHILQR-------------------------------EGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVP---------GVPT-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHR2-1", "uniprot_id": "ABCD1_RAT", "id": "D3ZHR2-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "---MPVLSTPS---------RPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVP----------------------AGESTQEASGATTAKA-------GMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVS--RTFLSVYVARLDGRLARCIVRKDPRAFSWQLL-QWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVQHCRFKRTG-DLEEAQAGPGSMVHSGVHIEGPLKIQGQVVDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSG--------VLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSAEDMRRK-----GCSEQQLEAILGIVHLRHILQR-------------------------------EGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVP---------GIPT-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33897-1", "uniprot_id": "ABCD1_HUMAN", "id": "P33897-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "---MPVLSRP----------RPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAP----------------------AGEPTQEASGVAAAKA-------GMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVS--RTFLSVYVARLDGRLARCIVRKDPRAFGWQLL-QWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGG--------VLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSVEDMQRK-----GYSEQDLEAILDVVHLHHILQR-------------------------------EGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RBC8-1", "uniprot_id": "ABCD1_DANRE", "id": "F1RBC8-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "---MSVYSKL----------PSQLKKPLVKKAVVLLIALYGVKKLSPYFFGKLKGRTSKQVKG---------------ADPLTSNGEPLVEAARKRKRSP-------AVNREFFDRLIRLLKILFPRLFCKELGLLGFHSLALIS--RTFLSIYVANLDGQIVKTIVKKDPRAFVVELT-KWLLIAIPATFVNSAIRYLEGQLTLAFRTRLVTHAYMLYFSDQTYYRVSNMDGRLANPDQSLTEDVVMFAASVAHLYSNLTKPILDVVVTCYTLIKTAESKGANTTWPSVIAGIVVALTAKVLRAFSPRFGKLVAEEARRKGDLRYMHSRIIANSEEIAFYGGHKIEMLQLQRSYNSLSRQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAVPIITATGYSKYDSEDVKQAALDMKEEDLVSERTQAFTTARSLLNAAADAVERIMVSYKEVTELAGYTARVYEMFEVFEDVRDGVYRRSATEVKPEETGAPQNVTHGMRVEGPLQIRGQVIDVEQGIKCENLPIITPTGDVVVSSLNMQVDEGMHLLITGPNGCGKSSLFRILSGLWPVYSG--------VLYKPSPDH----MFYIPQRPYMSVG-TLRDQVIYPHSVQEMQEK-----GITDRQLEEILQTVSLRYILER-------------------------------EGGWDAVSDWKDVLSGGEKQRMGMARMFYHKPQYALLDECTSAVSIDVEGKIFEAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWRFEKLDASTRISLQDEKIRLETQLSGIPKMQQRLTELCRILGEDSSLPTPGDEEEDEEEDEKQTERDVQSAGKEKDLME------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JUN3-1", "uniprot_id": "ABCD1_DROME", "id": "Q7JUN3-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "---MSVLSKYVDRIAEKCEHNGFTKHAFSYALVTSAILALTIKVTIPYVKNVNTTSSVRTQKGKTNGQLSPSTRDSSEEDFKLAEAEKLLVAQQLKKKATNNLVE-PGLNKEFLKHLQMLAKIMIPQAFCYETGLLSVHTFCLIS--RTFLSIYVAALEGALVKFIVRKDIKQFALVLL-KWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESR------VSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTS-VMESNQSNGIIEFRNGKPIAKGRIIYSDDP-KNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAG--------ELHIPRPVKDVPCMFYIPQRPYMSIG-SLCDQIIYPDTREDMKRK-----HITENELRSILKMVSLEHIAQR-------------------------------DS-FDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE-----EQKGQFLS---------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34230-1", "uniprot_id": "PXA2_YEAST", "id": "P34230-1", "name": "Peroxisomal long-chain fatty acid import protein 1", "aln": "--MISTASAFY---------QKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKKDSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMG---EGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKE----------PGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDANK------------------------GDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNEEKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALFNANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . ::: . : : . : .:: **:**: ** *:* :. :*. . * * :*: :.:**:*:** * : ::::. :: . *: :: : : : :. **:*: *: . : * ..* ** :*: : *: : . . . :: : :*: .*.* *. .* . :* :**.: :. ****: *:: *: : .: * :. : : : : *.:** *.. *::: ::**: . . .: * : * ** :.:.: *:: ::: .* * *: : ::: : * . :*::** :::.. *.: :. * **** **************.**** : . :**:******. :: :*:***.: :::: : : :* ** : * : . . :. : :*.: *: * :**:.:**::**:*::*:********: ::* ::: * . **:*::: **.:**::*.::*:*** *.::* ::. :: .: ", "identical_positions": 138, "similar_positions": 207, "identity": "15.32%" }, { "cls_id": "homologset.agr.SGD:S000001672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIJ7-1", "uniprot_id": "Q5XIJ7_RAT", "id": "Q5XIJ7-1", "name": "", "aln": "--------MKKMPL-FSKSHKNPAEIVKILKDNLAILEKQ----DKKTDKASEEVSKSLQAMKELLCGAQDKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRCPTVEYICSHPHILFMLLKGYE-------APQIALRCGIMLRECIRHEPLAKVILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRH-KVLVADFLEQNYDTI-FED-YEKLLQSENYVTKRQSLKLLGELILDRHNFTIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKAAP-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB16-1", "uniprot_id": "CB39L_MOUSE", "id": "Q9DB16-1", "name": "Calcium-binding protein 39-like", "aln": "--------MKKMPL-FSKSHKNPAEIVKILKDNLAILEKQ----DKKTDKASEEVSKSLQAMKEILCGTNDKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRCPTVEYISSHPHILFMLLKGYE-------APQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRH-KVLVADFLEQNYDTI-FED-YEKLLQSENYVTKRQSLKLLGELILDRHNFTIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKAAP-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9S4-1", "uniprot_id": "CB39L_HUMAN", "id": "Q9H9S4-1", "name": "Calcium-binding protein 39-like", "aln": "--------MKKMPL-FSKSHKNPAEIVKILKDNLAILEKQ----DKKTDKASEEVSKSLQAMKEILCGTNEKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYE-------APQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRH-KVLVADFLEQNYDTI-FED-YEKLLQSENYVTKRQSLKLLGELILDRHNFAIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKTAP-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06138-1", "uniprot_id": "CAB39_MOUSE", "id": "Q06138-1", "name": "Calcium-binding protein 39", "aln": "-----------MPFPFGKSHKSPADIVKNLKESMAVLEKQDIS-DKKAEKATEEVSKNLVAMKEILYGTNEKEPQTE-AVAQLAQELYNSGLLGTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYE-------SPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRH-KLLSAEFLEQHYDRF-FSE-YEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRAAQQEA--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ77-1", "uniprot_id": "D3ZJ77_RAT", "id": "D3ZJ77-1", "name": "", "aln": "-----------MPFPFGKSHKSPADIVKNLKESMAVLEKQDIS-DKKAEKATEEVSKNLVAMKEILYGTNEKEPQTE-AVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYE-------SPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRH-KLLSAEFLEQHYDRF-FSE-YEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRAAQQEA--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y376-1", "uniprot_id": "CAB39_HUMAN", "id": "Q9Y376-1", "name": "Calcium-binding protein 39", "aln": "-----------MPFPFGKSHKSPADIVKNLKESMAVLEKQDIS-DKKAEKATEEVSKNLVAMKEILYGTNEKEPQTE-AVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYE-------SPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRH-KLLSAEFLEQHYDRF-FSE-YEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T8Z7-1", "uniprot_id": "A0AB32T8Z7_DANRE", "id": "A0AB32T8Z7-1", "name": "", "aln": "-----------MPFPFGKSQKSPAEIVKSLKENVAYLEKLESSESKKCEKVAEEVSKNLSSLKEVLCGTGDKEPQTE-AVAQLAQELYNTNLLISLIANLQRIDFEGKKDVVHLFSNIVRRQIGARTPTVEYISSHSQILFMLLKGYE-------TSEVALNCGMMLRECLRHDPLARIVLFSEDFYCFFRYVEMSTFDIASDAFASFKDLLTRH-KIMCADFLETNYDRV-FTE-YEKLLHSENYVTKRQSLKLLGELLLDRHNFTVMTKYISRAENLKLMMNMLRDNSRNIQFEAFHVFKVFVANPNKTQPVLDILLKNQSKLVEFLSHFQTDRSEDEQFCDEKNYLIKQIRDLKRPAPAEES-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91891-1", "uniprot_id": "MO25_DROME", "id": "P91891-1", "name": "Protein Mo25", "aln": "-----------MPL-FGKSQKSPVELVKSLKEAINALEAG----DRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPADYVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFTLMAGYED-----AHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELLTRH-KLLCAEFLDANYDKF-FSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENLKLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFNDEKAYLIKQIKELKPLPEA----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32464-1", "uniprot_id": "HYM1_YEAST", "id": "P32464-1", "name": "Protein HYM1", "aln": "MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLT-QDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPE-AIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLD-SQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: : *. *.* : .: : : : :. . : *. *: :* * . *..: * : .* .: .: :* :: :.:: *: .: ::**.::. :*. : . . : **:*: :: . : :: * :: * * *: ** ::: *.:::* . :: **.:.::..*:*::::: :. :* * *:: :*:. . : . * . ::*: .***:*** ***..*:: * * ::*. **. .*****:*.:: ::* *:*:***:****:**.*.*.:*:.:**::*: **: ::. * : ::*. * **: :::::* .* ", "identical_positions": 85, "similar_positions": 145, "identity": "21.14%" }, { "cls_id": "homologset.agr.SGD:S000001673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L7T4-1", "uniprot_id": "A0ABK0L7T4_RAT", "id": "A0ABK0L7T4-1", "name": "", "aln": "MEIIRETALERTAQLLSLAWVAPSLSLFPFQSLFPALLFSLSFTFPPCCPPLSPACPSRAAQANGSTVCPAVSSLRCLCQPHCLAMGNEAS---YHSEMGT--HFDHDEIKRLGRSFKKMDLDKSGSLSVDEFMSLPELQQNPLVGRVIDIFDTDGNGEVDFREFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFRDVVRTMEIHKKLVVFVDHGQED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63811-1", "uniprot_id": "CANB2_MOUSE", "id": "Q63811-1", "name": "Calcineurin subunit B type 2", "aln": "-------------------------------------------------------------------------------------MGNEAS---YQTELCN--HFDQEEIRRLGKSFRKLDLDKSGSLSIEEFMRLPELQQNPLVGRVIDIFDTDGNGEVDFHEFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFSDVVKTMEIHKKLVVFVEHGQEDLKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LZ3-1", "uniprot_id": "CANB2_HUMAN", "id": "Q96LZ3-1", "name": "Calcineurin subunit B type 2", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPAEMCS--HFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63098-1", "uniprot_id": "CANB1_HUMAN", "id": "P63098-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63100-1", "uniprot_id": "CANB1_RAT", "id": "P63100-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63810-1", "uniprot_id": "CANB1_MOUSE", "id": "Q63810-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3BEF6-1", "uniprot_id": "A0A8M3BEF6_DANRE", "id": "A0A8M3BEF6-1", "name": "", "aln": "-------------------------------------------------------------------------------------MAHKYSTMGKPLCGMTSVRFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEMKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48451-1", "uniprot_id": "CANB1_DROME", "id": "P48451-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNETS---LPMDMCS--NFDADEIRRLGKRFRKLDLDNSGALSIDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTICFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24214-1", "uniprot_id": "CANB2_DROME", "id": "Q24214-1", "name": "Calcineurin subunit B type 2", "aln": "-------------------------------------------------------------------------------------MGNETS---LPMEMCS--NFDADEIRRLGKRFRKLDLDNSGALSVDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIGFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25296-1", "uniprot_id": "CANB_YEAST", "id": "P25296-1", "name": "Calcineurin subunit B", "aln": "-------------------------------------------------------------------------------------MGAAPS--KIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAIETTEVAKSLTLQYDV-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * .** :**.** : * *:* *.**::. :*** :* : ***. *::::**:*..*:***:*** * * ** :*.: ****** ***:*:**:******* ***:***.** * ****:**::* *.* **::**:** .: :: *.:.: ", "identical_positions": 81, "similar_positions": 46, "identity": "30.11%" }, { "cls_id": "homologset.agr.SGD:S000001674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Y2-1", "uniprot_id": "DPH2_RAT", "id": "Q568Y2-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "-----------MESTFSSPAEAALQREAGVPGQFTP---PEDLDRVYELERVTRFICDL-GCQRVALQFPDQLLGDAGAVAARLEEVTG---SKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPASLLPITFVLGRRPVALELCAKAFEAQNPD-PTALVVLLSEPACAHALEPLATLLRPKYQDLLISSPALPLPVGSLSSQPESLER----------FGRRFPLNPGRSLEEYGAFYVGASQASSDPNLDPDLSRLLLGWTPGRPFFSCCPDTGQTQDQGA-----KAGRLRARRLYLVERARDARVVGLLVGTLGVAQHLEALAHLRKLTEAAGKRSYVLALGKPTPAKLANFPEMDVFVLLACPLGALTLQPSGGFFRPILTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFHVPLPPPE--SELWDTPDVSLISG-------ELRPPPPWKS--SDDTKCSALTPRPQ----LELAESSPAASFLSSRSWQGLEPRLGQTPVK----EAVQGRRGIAIAYEDEGSS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR25-1", "uniprot_id": "DPH2_MOUSE", "id": "Q9CR25-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "-----------MESTFSSPAEAALQREAGVPGQFTP---PEDLDRVYELERVTKFVCDL-GCQRVTLQFPDQLLGDAGAVAARLEEVTG---AKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPASQLPITFVLGQRPVALELCAKAFEAQNPD-PTAPVVLLSEPACAHALEPLAMLLLPKYQDLLISRPALPLPVGSPSSQPESLER----------FGRCFPLNPGRRLEEYGAFYVGASQASSDSSLDPDLSRLLLGWTPGRPFFSCCPDTGQTQDQGA-----KAGRLRARRLYLIERARDARVVGLLAGTLGVARHREALAHLRKLTEAAGKRSYVLAVGKPTPAKLANFPEMDVFVLLACPLGALAPQPSGGFFRPVLTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFHVPLPPPE--SELWDTPDVSLISG-------ELRPPPPWKS--SDDTRCSALIPRPQ----LELAESSPAASFLSSRNWQGLEPRLGQTPVK----EAVRGRRGIAIAYEDEGSS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQC3-1", "uniprot_id": "DPH2_HUMAN", "id": "Q9BQC3-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "-----------MESMFSSPAEAALQRETGVPGLLTP---LPDLDGVYELERVAGFVRDL-GCERVALQFPDQLLGDAVAVAARLEETTG---SKMFILGDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPVAFVLRQRSVALELCVKAFEAQNPD-PKAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLER----------FGRRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLGWAPGQPFSSCCPDTGKTQDEGA-----RAGRLRARRRYLVERARDARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILAPCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPPE--SELWETPDVSLITG-------DLRPPPAWKS--SNDHGSLALTPRPQ----LELAESSPAASFLSSRSWQGLEPRLGQTPVT----EAVSGRRGIAIAYEDEGSG--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QN59-1", "uniprot_id": "DPH2_DANRE", "id": "A4QN59-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "-----------MTDAFSSSSEAVLQRSVTSTHSFHP---SGDLLLLYQTPETCRFITSN-HFKKVALQFPDELLPDAVRVSAEIEDKTK---AKTYILGDTSYGSCCVDEVAAEHVGADCIVHYGSSCLSP-CRRLPLLYVFGKRPIDVHQCASSFKELYPN-LQSHIIVLFDVTYSHAIDDLRTLLCDVYPNVVVSRLKTDHSCGAELIQDSCVDLQSNDDGVIFKFGRQFRIKEGQTVNDYSIFYIGQEGLT--------LTNFMMSWN-NCVFSSFNPETSTGRVESV-----QINKALMKRYYAIERAKDASVVGILVGTLGVANYLIIIEQLKDTIQRAGKKSYMFAMGKINVPKLANFLEIDIYVLVACPENSLLD--SSEFYRPVVTPFEMELACNKHREWTG--EYVTDFRELLPGGSSHVGFPEPSQSATEEETTDVSLITG-------ALRSCSTNSSEMMHNSETSSLVLRNQT---LTVANTNAAASFLAGRSWQGLEPKLGQTPVV----KAVKGQRGIAIAYEEEGNEDASTQQKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFE9-1", "uniprot_id": "Q9VFE9_DROME", "id": "Q9VFE9-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "-----MTSSETSASAFSSSDTAALERQAEVEQPVT----LEQIWNENHRRSSVDWIRKS-GYKRVCLQFPDDYLPHSNAISVGLKELLAPEDVKVFILADTTYGSCCVDEIAAAHVDADSVIHFGNACRSR-AARLPVLYLYPELPLDVNVLLSKLQGLRAESIDRQVCVYLDIGYQHVYGEKLKKQLSEILEPKELLLELFPPIEAESTTTRETTN-----------------------LERICIFIGADNQR--------FANLSLTAPAAVQWHIYDGSSDSLSSKNP-----LTAQFIRRRYFHIEKCKDAQTLGLIVATLSAEGYLDVVTRLQTMAKGRGIKTQLISVGRINPAKLANFLEIDCFVLIGCPFNNMYD--SKEYYKPIVSVFEAEMALNPAWHMRYPEAYVTDFKQLLPEGRSFLPFDAAD-----IPENDVSLVSG-------RLRGAVNDSLETGGDPASLALATQAK----MALMTTDTGLSFED-RTWQGLDPALGQTEPA----KLQQGLSGIPINYSHQ-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32461-1", "uniprot_id": "DPH2_YEAST", "id": "P32461-1", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "aln": "MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLISAYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTAYSACCVDEVAAEHVHAEVVVHFGDACLNA-IQNLPVVYSFGTPFLDLALVVENFQRAFPD-LSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFH-----------VPEDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDPALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKKHYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEEVTWTG--KWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTHLELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGADIEEGISGVARGYGFDREDAMKKENK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ::*. : . :: . :.* *****: : .: : ::. * ::*.**:*.:**** :.* :. *: ::*:* :* . **: : : : . :: .: : : : : . . :: . : .: : .: :* :. .: * :*::. **. : .* : : :: :*: . .***** ::* : ::.*. . : :::*::: * : * . :..: : : : . :..:: * ** . : * : : ... * *.*:** . :..* . * *:. * : ", "identical_positions": 54, "similar_positions": 127, "identity": "9.82%" }, { "cls_id": "homologset.agr.SGD:S000001675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF13-1", "uniprot_id": "D3ZF13_RAT", "id": "D3ZF13-1", "name": "Acyl carrier protein", "aln": "MASRVLCACVRRLPAAFAPLPR-----LPTLALARPLSTILCPEGIWRRTGTLQPTLALAQVPGTVTHLCRQYSDAPPLTLEGIRDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR21-1", "uniprot_id": "ACPM_MOUSE", "id": "Q9CR21-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLCACVRRLPAAFAPLPR-----LPTLALARPLSTTLCPEGIRRRPGALQSALALAQVPGTVTHLCRQYSDAPPLTLDGIKDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14561-1", "uniprot_id": "ACPM_HUMAN", "id": "O14561-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLSAYVSRLPAAFAPLPR-----VRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGRVTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCE9-1", "uniprot_id": "F1QCE9_DANRE", "id": "F1QCE9-1", "name": "Acyl carrier protein", "aln": "MASRALAQCVRSLARASARLNEGRTACVLLAAAQRPLSSWTCNQRTSR--------TELLRIPSPSVHLCRHYSDAPPLTLDDIQERVLYVLKLYDKINP----DVLKSTSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDGDGEKLMTPEEIVTYIADKKDVYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94519-1", "uniprot_id": "ACPM_DROME", "id": "Q94519-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MSFTQIARSCSRLAATLAPRRVASG-ILIQSQASRMMHRIAVPSMTSQ--------LSQECRGRWQTQLVRRYSAKPPLSLKLINERVLLVLKLYDKIDP----SKLNVESHFINDLGLDSLDHVEVIMAMEDEFGFEIPDSDAEKLLKPADIIKYVADKEDVYE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32463-1", "uniprot_id": "ACPM_YEAST", "id": "P32463-1", "name": "Acyl carrier protein, mitochondrial", "aln": "-----MFRSVCRISSRVAPSAY-----------RTIMGRSVMSN----------------------TILAQRFYSAN-LSKDQVSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPDKVADELRSVGETVDYIASNPDAN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. * : . * ::: *: . : :**: *:* :** .* . :. ::* :******** **:::*:*:**.:**** .::* : : *:*.: *. ", "identical_positions": 33, "similar_positions": 38, "identity": "20.0%" }, { "cls_id": "homologset.agr.SGD:S000001676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZV9-1", "uniprot_id": "PP1R7_RAT", "id": "Q5HZV9-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGG-IVADLSQQSLKDGVERGAEDPEEEHELAVDMETISLDR--DAEDVDLNHYRIGKIEGFEV--LKKVKSLCLRQNLIKCIENLDELQS--LRELDLYDNQIKKIEN-LEALTELEVLDISFNLLRNIEGIDKLTQLKKLFLVNNKINKIENISTLQQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALSNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATFVRF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UM45-1", "uniprot_id": "PP1R7_MOUSE", "id": "Q3UM45-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGGGIVANLSEQSLKDGVDRGAEDPEEEHELAVDMETINLDR--DAEDVDLTHYRIGKIEGLEV--LKKVKSLCLRQNLIKCIENLEELQS--LRELDLYDNQIKKIEN-LEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKIENISNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATYVRF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15435-1", "uniprot_id": "PP1R7_HUMAN", "id": "Q15435-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSG-IVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDR--DAEDVDLNHYRIGKIEGFEV--LKKVKTLCLRQNLIKCIENLEELQS--LRELDLYDNQIKKIEN-LEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATFVRF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PL1-1", "uniprot_id": "PP1R7_DANRE", "id": "Q32PL1-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "-MATLSVGEPQE---MEVDRRGESEESGDDETK------------RKSLNGEVDSLQAPSTVPEESPVDMDTITLDP--EEEDVDLVHCRIGKIEGLEV--LLKAKTISLRQNLIKRIENLESLVS--LRELDLYDNQIRKLEN-LQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLTSLQMLELGSNRIRVIEN--LDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKIENISHLTDLKEFWMNDNQIEN-WADL-DELKNAKGLETVYLERNPLQKD--PQYRRKIMLALP-SVRQIDATFIRF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEK8-1", "uniprot_id": "Q9VEK8_DROME", "id": "Q9VEK8-1", "name": "", "aln": "------MG--------DADRAMNEPEAAK----------------------TVSGIQVIP--AEDVASIEDIITIDP--DCYELDLNHRRIEKLENFEP--LTRIERLFLRWNLIKKIENLSSLKT--LIELELYDNQITKIEN-LDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIEN--IEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNHNGVDD-WKDI-ELLKVNKALQTIYLEYNPLAKD--VRYRSKLRDILP-QLQKIDATLCKVPGT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36047-1", "uniprot_id": "SDS22_YEAST", "id": "P36047-1", "name": "Protein phosphatase 1 regulatory subunit SDS22", "aln": "-----------------MDKNSVNKDSEE--------------------KDERHKIEVVDDTNPDFITADSELTQDLPDDVEVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKIKHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKIENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKIDATYIRG---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . :: . : . :. * : :** * :* .:*.:: : . : : ** ***: *.::. * : :*::***:* ::.. :: *..* **:*** : :*:.::.*. ::::::: * * .* *:. * .* ****.*::: ** :: * .*..::**.*.*.:: **. * ** :**:*:*:: *:*.*:.*.**.***:*.* : :*.*.:* ** **:: *::. : *:.:* * ::* . * ::. : .: : *. *:*:*** **: : ** *: ** .:::**** : ", "identical_positions": 97, "similar_positions": 124, "identity": "25.66%" }, { "cls_id": "homologset.agr.SGD:S000001678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEA4-1", "uniprot_id": "MIA40_MOUSE", "id": "Q8VEA4-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEDIKGSDCIDQFRAMQECMQKYPDLYPQ--------------------DEEEEEE-----------------------------------------------------------------------------------------------------------------------AKPVEPVEETADTKVSAAKEQGTSS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDY6-1", "uniprot_id": "D3ZDY6_RAT", "id": "D3ZDY6-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYCWQEGKDRIIFVTKEDHETPSSAKLVADDPNDFYEEHGLILPNGDINWNCPCLGGMASSPCGEQFKSAFSCFYYSTKDIKGLDCIDQFRAMQECMQKYPDLYPQ--------------------DKEEEEE-----------------------------------------------------------------------------------------------------------------------AKPMEPVEETADTKASAAKEQGASS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BJN5-1", "uniprot_id": "MIA40_RAT", "id": "Q5BJN5-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEDIKGSDCIDQFRAMQECMQKYPDLYPQ--------------------DEEEEEE-----------------------------------------------------------------------------------------------------------------------AKPVEPVEETADTKASAAKEQGASS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4Q1-1", "uniprot_id": "MIA40_HUMAN", "id": "Q8N4Q1-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQED-----------------EDEEEERE-----------------------------------------------------------------------------------------------------------------------KKPAEQAEETAPIEATATKEEEGSS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1ASY6-1", "uniprot_id": "B1ASY6_MOUSE", "id": "B1ASY6-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAYSPQEEKDKVVFVTKEDHESPSNAELVVDEPNDPHAEYGLILPSGSINWNCPCLGGMASGPCGEHFKSAFSCFHHSTEEVKGSDCASEYQALKECMQKYPDIYPQEENESESEDDNSDIYQEALQDEEEEEEEEDDDVDDYYYEGLENAEVEEEEEEEEDEDDYYYEVEEYEEEEEEEEEDYYHENNYYNNNDYYDDEDYYQYEDNYYKDEDDEIYYEADYQEEGEDEEDEEDEDAFYEANYFGEEDEEEPAEPAEPAEPAKPKEEADAAEASSGGKLQYFSA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DEI8-1", "uniprot_id": "MIA40_DANRE", "id": "Q6DEI8-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYCKQEGKDCIIFVTKEDHEAPSNAELVEDDPNDPYEDHGLILPNGDINWNCPCLGGMASGPCGQQFKDAFSCFHYSKEEIKGSDCVENFRGMQECMQKYPELYPQED------------------DNDSAPSGGAN-------------------------------------------------------------------------------------------------------------------TAPTDSLPASSTDSTAAAATENPATS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAA6-1", "uniprot_id": "Q9VAA6_DROME", "id": "Q9VAA6-1", "name": "CHCH domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFSYCKEYGKDKVIFVTKEDHATPSTIELPPPEKPE-----GVITKDGKINWSCPCLGGMATGPCGVDFREAFSCFQNSTADPKGSDCYDAFTKMRDCFQKYPTVYNKSG-----------------GDDDDDDGLSEALDTDAG----------------------------------------------------------------------------------------------------------SVGGQNADPLADVGNNGGGDELVSPNSSSVVPKA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36046-1", "uniprot_id": "MIA40_YEAST", "id": "P36046-1", "name": "Mitochondrial intermembrane space import and assembly protein 40", "aln": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETS--------------DDEEPQDKVKVN------------------------------------------------------------------------------------------------------------------TIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : *: :::. . : : . *.***.******** .*** .*:.***** * : ** ** . : :::*::*** * : *.:. ", "identical_positions": 33, "similar_positions": 31, "identity": "6.21%" }, { "cls_id": "homologset.agr.SGD:S000001679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EGY4-1", "uniprot_id": "YKT6_RAT", "id": "Q5EGY4-1", "name": "Synaptobrevin homolog YKT6", "aln": "-MKLYSLSVFYKGEPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSAKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFSKQVDRIDWP--VGSPATIHYTALDGHLSRYQNPREADPMSKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQW1-1", "uniprot_id": "YKT6_MOUSE", "id": "Q9CQW1-1", "name": "Synaptobrevin homolog YKT6", "aln": "-MKLYSLSVLYKGDPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSGKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFSKQVDRIDWP--VGSPATIQYTGLDDHLSKYQNPREADPMSKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15498-1", "uniprot_id": "YKT6_HUMAN", "id": "O15498-1", "name": "Synaptobrevin homolog YKT6", "aln": "-MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWP--VGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUN8-1", "uniprot_id": "YKT6_DANRE", "id": "Q7ZUN8-1", "name": "Synaptobrevin homolog YKT6", "aln": "-MKLYSLSVLHKGSTKANLLKATYDLSSFSFFQRSSVQEFMTFTSALIVERSALGSRASVKEQEYLCHVYVRNDNLGGVVIADSEYPSRVCFTLLDKVLDEFSRQVNSIDWP--SGSPATIQYTALDSHLARYQNPREADAMTKVQAELDETKIILHNTMESLLERGEKLDDLVQKSEHLGNQSKAFYKTARKQNSCCEIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3M8-1", "uniprot_id": "Q9W3M8_DROME", "id": "Q9W3M8-1", "name": "", "aln": "MVKLFALSIFHKGASEARLLKTASDLQSFSFFQRGTVNEFMTFASKTIVERTQPALRQSVKQDAYMCHVYVRADNLAGVLIADHEYPHRVAHTLITKILDDFTAKVSADQWP--NGTEATISFDLLPAFLARYQNPVEADPLTKMQNDLDETKIILKNTIEAVLERGEKLDDMVSKSEKLSLQSKAFYKTAKKTNSCCSFT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36015-1", "uniprot_id": "YKT6_YEAST", "id": "P36015-1", "name": "Synaptobrevin homolog YKT6", "aln": "-MRIYYIGVFRSGGEKALELSEVKDLSQFGFFERSSVGQFMTFFAETVASRTGAGQRQSIEEGNYIGHVYARSEGICGVLITDKEYPVRPAYTLLNKILDEYLVAHPKEEWADVTETNDALKMKQLDTYISKYQDPSQADAIMKVQQELDETKIVLHKTIENVLQRGEKLDNLVDKSESLTASSKMFYKQAKKSNSCCIIM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: :.:: .* :. *. . *:..*.**:*.:* :**** : :..*: . * *::: *: ***.* :.: **:*:* *** * ..**: *:**:: :*. : :: * .:::**:* :**.: *:* :******:*::*:* :*:******::*.*** * .** *** *:* **** : ", "identical_positions": 74, "similar_positions": 70, "identity": "36.82%" }, { "cls_id": "homologset.agr.SGD:S000001680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZB2-1", "uniprot_id": "D3ZZB2_RAT", "id": "D3ZZB2-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWSSDRLAGAGS---GGAVVTVAFTNARDCFLHLPRHLVAQLHLLQNQAIEVTGDHQPTYLSWVEGRHFNDQSENVAEINRQVGQKLGLSSGD---QVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEE-HLLDQIRIVFPKAIVPIWVDQQTYIFIQIVALMPTAPYGRLETNTKLLIQPKTRQAKESTFPKEGDARGQAHNYGREQKGTVKELQTKQLHKNTEAVPVSNGRNPEVPGDS-VKPRWWAVLGSMFSFGPDNKQESAWGSLELGAFKNMQSQTVPLDSIFRVCQVQPPSVHNTPANSVFHKHCTVHVFPWDQEYFDVEPSFTVVYGKLVKLHSPKQQQDKSKQGVLLPEKEKQLSQSPGHKRIGSDGSEEAAETCVLKVVWNGLEELKNATEFTKSLEPLHHGKVWIPADLRKRLNIEMHAVVRITPLETTPVIPRALRLQPAENLPRDVSEEEVKAVFSSWLQESATTMFPLIISKQECIKLEIKDGLKEFSLSIVHSQEKEKEQGRTVFVLSPILLQKISVQVLLEPMIG-EHSEEIDILLPSLTLSSLGGVSSLSVSAMEHITHSLLGRP-LSRQLMALVAGLRNGALLITGGKGSGKSTLAKAICKEAHDALD-AHVEMVDCKALRGKR-LESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSTPEHEHSPEAVQSQR---LAHALNNMIKEFVSMGSLVALIATSQLQHSLHPSLVSAQGVHTFQCIQHIQPPDQEQRCEILHSVVKNKLGCDISKSPDLDLKCIAKETEAFVARDFTVLVDRAIHSSLSRQQNP---TREGLTLTTADFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIQGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKS---------LPLADDVDLQHVASVTESFTGADLKALLYNAQLEALQGRLLPGGLHDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGASCDLSSHCLSAPSSMTQDLPATPGKDPLFTQHPVFRTPSQEGSQDLTQEQRDQLRADISIIKGRYQSQSGEDESLNQPGPIKTSFAISQAHLMTALAHTRPSINEDEGKEFAELYENFQNPKK-RKNQSGTVFRTGQKVTLNFVLTPHFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BL07-1", "uniprot_id": "PEX1_MOUSE", "id": "Q5BL07-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWSSDRLAGAGS---GGAVVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVASDHQPTYLSWVEGRHFNDQSENVAEINRQVGQKLGLSSGD---QVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEQ-HLLDQIRIVFPKAVVPIWVDQQTYIFIQIVTLMPAAPYGRLETNTKLLIQPKTRQAKESTFPKEGDAHGQVHSYGREQKGLSKELQTRQLHTNSEGITASNGRDPKVPGGP-LKPSWWAVLGSMLSFGPDSKQESAWGSLELGAFKNMQSQAAPLEGTFRVCQVQPPSARTTTATSVFHKHCTAHVFPWDQEYFDVEPSFTVTYGKLVKLHSPKQQQDKSKQGVLLPDKEKQLSKSPDHKQISSNRSEEAAEACVLKVVWNGLEELKNATEFTESLELLHRGKVWIPDDLRKRLNIEMHAVVRITPLETTPKIPRSLKLQPRENLPKDVNEETIKTVFSSWVQQSATTMLPLVISKEERIKLEIKDGLREFSLSTVHSQEKEKEEGKTVFVLSSILLQKISVQVLLEPMIKEEQSAEIDFLLPSLTLSSLGGVSALGASAMEHITHSLLGRP-LSRQLMALVAGLRNGALLITGGKGSGKSTFAKAICKEAQDTLD-ARVETVDCKALRGKR-LESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSVPEQEHSPEAVQSQR---LAHALNDMIKEFVSTGSLVALIATSQLQQSLHPSLVSAQGIHTFQCVQHLQPPNPEQRCEILHSVVKNKLGCDISNFPDLDLQCIAKDTEAFVARDFTVLVDRAIHSSLSRQHSS---SREDLTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKS---------LALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQGRLLPSGLPDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLEQSLLSLEMSEILPDESKFNMYRLYFGSSYESELGNGTPSDLSSHCLSAPSSVTQDLPAAPGKDPLFTQHPVFRTPSQEGCQDLTQEQRDQLRAEISIIKGRYRSQSGEDESLNQPGPIKTTFAISQAHLMTALAHTRPSISEDEGKEFAELYENFQNPKK-RKNQSGTVFRTGQKVTLA---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43933-1", "uniprot_id": "PEX1_HUMAN", "id": "O43933-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWGSDRLAGAGG---GGAAVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVVWSHQPAFLSWVEGRHFSDQGENVAEINRQVGQKLGLSNGG---QVFLKPCSHVVSCQQVEVEPLSADDWEILELHAVSLEQ-HLLDQIRIVFPKAIFPVWVDQQTYIFIQIVALIPAASYGRLETDTKLLIQPKTRRAKENTFSKADAEYKKLHSYGRDQKGMMKELQTKQLQSNTVGITESNENESEIPVDSSSVASLWTMIGSIFSFQSEKKQETSWGLTEINAFKNMQSKVVPLDNIFRVCKSQPPSIYNASATSVFHKHCAIHVFPWDQEYFDVEPSFTVTYGKLVKLLSPKQQQSKTKQNVLSPEKEKQMSEPLDQKKIRSDHNEEDEKACVLQVVWNGLEELNNAIKYTKNVEVLHLGKVWIPDDLRKRLNIEMHAVVRITPVEVTPKIPRSLKLQPRENLPKDISEEDIKTVFYSWLQQSTTTMLPLVISEEEFIKLETKDGLKEFSLSIVHSWEKEKD--KNIFLLSPNLLQKTTIQVLLDPMVKEENSEEIDFILPFLKLSSLGGVNSLGVSSLEHITHSLLGRP-LSRQLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLD-AHVERVDCKALRGKR-LENIQKTLEVAFSEAVWMQPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQR---LAHALNDMIKEFISMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDLQHVAKETGGFVARDFTVLVDRAIHSRLSRQSIS---TREKLVLTTLDFQKALRGFLPASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILNVLSDS---------LPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGTSSDLSSQCLSAPSSMTQDLPGVPGKDQLFSQPPVLRTASQEGCQELTQEQRDQLRADISIIKGRYRSQSGEDESMNQPGPIKTRLAISQSHLMTALGHTRPSISEDDWKNFAELYESFQNPKR-RKNQSGTMFRPGQKVTLA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUC7-1", "uniprot_id": "Q9VUC7_DROME", "id": "Q9VUC7-1", "name": "Peroxisomal ATPase PEX1", "aln": "-----------M---FKRTFKVVYRPIRSNFVLLPDQYYGVVSTYDTGCLSLQYNGRTHYASWAPQKGGGGIKDTEIGINARAAKEIGLHEND---LVKCALIADVLNLRSVHVTPVSSKDWEIIELSTEKISG-SVLEQTRIVNSTQILIVWINKSMQVALTVDRLKPHMNYGRIDHNTELVVAPNLYKGLTNGTSN-GVIEENTKLSRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQRNKR---------QDHMERLKKDLRRESSR-SFEFRVIRGLWREQAQESDVFVNGKHLP-------------------------EFFDLD--------LFYCMHTAADKDYYVRVRTVEDDIEDDLPETIHP-------------------------------------------SIELNANLMKLLGIKELERVVLRPKTTVVNFVEKIELFANKKTHYKIMENAFKRFVIERTQH-----KPMLFNQEEVVRLED-----DLLVTVGILPEHFRYCVVDAQFLKESKIYAADLVRPVGEIIKEETPP----------TSPLSVQDLIQLPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRK-TESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGE---QSSQDGEYYNR---MADTVYQLIVQYTTN-NAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILR-----ELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSST---------LSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEK--------------------------------------------------------------------------------------------------------------------------------------------------------LAKKISLKQKHLIESFQTTRPSLSASDVAKYHRTYARFTNKEK-TSR-----EFVAKRATLA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24004-1", "uniprot_id": "PEX1_YEAST", "id": "P24004-1", "name": "Peroxisomal ATPase PEX1", "aln": "MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQEFGIAVHSHNSDIPIVHLGWDG--HDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYDHTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEG-IVTKFKIDRVEPSMKSARITDGSLVVVAPKVNKTRL-----------VKAEYGHSNKTILKNGAIQLLKKVILRSTVCKMDFPKD-----------NLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIG---------------------------------------VFIKCDSQIPENHIALSSHLWDAFFTHP----------------------------------------------------MNGAKIKLEFLQMNQANIISGRNATVNIK-----YFGKDVPTKSGDQYSKLLGGSLLTNN-------LILPTEQIIIEIKKGESEQQLCNLNEISNESVQWKVTQMGKEEVKDIIERHLPKHYHVKETGEVS---------RTSKDEDDFITVNSIKKEMVNYLTSP-----------IIATPAIILDGKQGIGKTRLLKELINEVEKDHH-IFVKYADCETLHETSNLDKTQKLIMEWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFNKDNKRIRVLFSGKQKTQINPLLFD---KHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKLN--RDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDN-------VVTRELFSKSLSAFTPSALRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQGLCYNAYLKSVHRWLSAADQSE-----------------------------------------------------------------------------------------------------------VVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVHETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNGENSIDIGSRLSLM---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :: : : . . . .* .. :. ** . .* . . : .. .* * * ::.****:: : :. :*.* *** . . ::: : : : * .*: .: ::: *: : . . *: . * . .: . : :.. :: . .. : : : :: : . : * :: : .. : :. . :: * . . . :: * : :* : : .: . . : :. . . : .: . : : ::: * .* **: : : : .: . .: . . : :. ** : : . *::::*:::: : . : * :. : : : :: : . . : :: : : :: * . * .. : : * :* : .:. **:: .: * .: *: :.:: :. : .. : * : . :: .: .* .. :* :.: *::* :* *:* ::*:**** ** *** *.. :* . :.:**::***:* *:** **: :*::* **::.:**:******:*:**:****.*************::**.***:** ::******:*:*.****.**:*: * * * *: *: .: .: :.* . .*:. .* * .::***::.: .* : ::: * . . :. .*: : *:**:. .: : * * : .. ..: :* ", "identical_positions": 148, "similar_positions": 287, "identity": "11.21%" }, { "cls_id": "homologset.agr.SGD:S000001684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI33-1", "uniprot_id": "D3ZI33_RAT", "id": "D3ZI33-1", "name": "Ribitol-5-phosphate transferase", "aln": "-----MSRVNKNVVLALLTLMSC-------AFLLFQLYYYKHYLS---ARNGTG------------SSKSKGNRVGFDSTQWRAVKKFIMLTSSQNVPVFLIDP-------WILESINKNFEQVKNASQGSASECRFFCVPRDFTAFALQYHLWKNEDG-------------------------------------------------------------------WFQMAENMG-----FQCLKIESKDPRLDGIDSLSGTEIPLHYVCKLATHAIHLVVFHERSGNYLWHGHLR-------------------------------LKGHMDRKFVPFRRLQFGRYPGAFDRPELQQVTVDG----------------------LDMLIPK----DPGRFLEEVPHSR----------------FIECRYKEARAFLQQYVDDN-----------------------TVDAMAFRKRAKELLQLAAKTLKALGVPFWLSSGTCLGWYRQCSIIPYSKDVDLGIFIQDYKP-----DIVLAFQDAGLPLKHKFGKVEDSLELSFQGQADVKLDIFFFYEET------------------------------DHMWNGGTQARTG-------------------------------------------------------------------------------------KKFKYLFPKFTLCWTEFVDIKVHVPCETVDYIEANYGKAWKIPVKTWD-------------------------WKSSPPNVQ---PNGVWPIS----------------------EWDEVIQLY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R507-1", "uniprot_id": "FKTN_MOUSE", "id": "Q8R507-1", "name": "Ribitol-5-phosphate transferase FKTN", "aln": "-----MSRINKNVVLALLTLTSS-------AFLLFQLYYYKHYLS---ARNGPG------------SSKSKGNRVGFDSTQWRAVKKFIMLTSSQNVPVFLIDP-------WILESINKNFEQVKNASQGPASECRFFCVPRDFTAFALQYHLWKNEDG-------------------------------------------------------------------WFRIAENMG-----FQCLKTESKDPRLDGIDSLSGTEIPLHYVCKLTTHAIHLVVFHERSGNYLWHGHLR-------------------------------LKGHMDRKFVPFRKLQFGRYPGAFDRPELQQVTVDG----------------------LDMLIPK----DPGRFLEEVPHSR----------------FIECRYKEARAFLQQYIDDN-----------------------TVDAMVFRKRAKELLQLAAKTLKDLGVPFWLSSGTCLGWYRQCGIIPYSKDVDLGIFIQDYKP-----DIILAFQEAGLPLKHKFGKVEDSLELSFQGKNDVKLDIFFFYEEA------------------------------DHLWNGGTQARTG-------------------------------------------------------------------------------------KKFKYLFPKFTLCWTEFVDIKVHVPCETVDYIEANYGKTWKIPIKTWD-------------------------WKSSPPNVQ---PNGIWPIS----------------------EWDEVIQLY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75072-1", "uniprot_id": "FKTN_HUMAN", "id": "O75072-1", "name": "Ribitol-5-phosphate transferase FKTN", "aln": "-----MSRINKNVVLALLTLTSS-------AFLLFQLYYYKHYLS---TKNGAG------------LSKSKGSRIGFDSTQWRAVKKFIMLTSNQNVPVFLIDP-------LILELINKNFEQVKNTSHGSTSQCKFFCVPRDFTAFALQYHLWKNEEG-------------------------------------------------------------------WFRIAENMG-----FQCLKIESKDPRLDGIDSLSGTEIPLHYICKLATHAIHLVVFHERSGNYLWHGHLR-------------------------------LKEHIDRKFVPFRKLQFGRYPGAFDRPELQQVTVDG----------------------LEVLIPK----DPMHFVEEVPHSR----------------FIECRYKEARAFFQQYLDDN-----------------------TVEAVAFRKSAKELLQLAAKTLNKLGVPFWLSSGTCLGWYRQCNIIPYSKDVDLGIFIQDYKS-----DIILAFQDAGLPLKHKFGKVEDSLELSFQGKDDVKLDVFFFYEET------------------------------DHMWNGGTQAKTG-------------------------------------------------------------------------------------KKFKYLFPKFTLCWTEFVDMKVHVPCETLEYIEANYGKTWKIPVKTWD-------------------------WKRSPPNVQ---PNGIWPIS----------------------EWDEVIQLY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36044-1", "uniprot_id": "MNN4_YEAST", "id": "P36044-1", "name": "Mannosyltransferase regulator 4", "aln": "MLQRISSKLHRRFLSGLLRVKHYPLRRILLPLILLQIIIITFIWSNSPQRNGLGRDADYLLPNYNELDSDDDSWYSILTSSFKNDRKIQFAKTLYENLKFGTNPKWVNEYTLQNDLLSVKMGPRKGSKLESVDELKFYDFDPRLTWSVVLNHLQNNDADQPEKLPFSWYDWTTFHELNKLISIDKTVLPCNFLFQSAFDKESLEAIETELGEPLFLYERPKYAQKLWYKAARNQDRIKDSKELKKHCSKLFTPDGHGSPKGLRFNTQFQIKELYDKVRPEVYQLQARNYILTTQSHPLSISIIESDNSTYQVPLQTEKSKNLVQSGLLQEYINDNINSTNKRKKNKQDVEFNHNRLFQEFVNNDQVNSLYKLEIEETDKFTFDKDLVYLSPSDFKFDASKKIEELEEQKKLYPDKFSAHNENYLNSLKNSVKTSPALQRKFFYEAGAVKQYKGMGFHRDKRFFNVDTLINDKQEYQARLNSMIRTFQKFTKANGIISWLSHGTLYGYLYNGMAFPWDNDFDLQMPIKHLQLLSQYFNQSLILEDPRQGNGRYFLDVSDSLTVRINGNGKNNIDARFIDVDTGLYIDITGLASTSAPSRDYLNSYIEERLQEEHLDINNIPESNGETATLPDKVDDGLVNMATLNITELRDYITSDENKNHKRVPTDTDLKDLLKKELEELPKSKTIENKLNPKQRYFLNEKLKLYNCRNNHFNSFEELSPLINTVFHGVPALIPHRHTYCLHNEYHVPDRYAFDAYKNTAYLPEFRFWFDYDGLKKCSNINSWYPNIPSINSWNPNLLKEISSTKFESKLFDSNKVSEYSFKNLSMDDVRLIYKNIPKAGFIEVFTNLYNSFNVTAYRQKELEIQYCQNLTFIEKKKLLHQLRINVAPKLSSPAKDPFLFGYEKAMWKDLSKSMNQTTLDQVTKIVHEEYVGKIIDLSESLKYRNFSLFNITFDETGTTLDDNTEDYTPANTVEVNPVDFKSNLNFSSNSFLDLNSYGLDLFAPTLSDVNRKGIQMFDKDPIIVYEDYAYAKLLEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQEEEEKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNKKNEDEEKKKQEEEEKKKNEEEEKKKQEEGHSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::::..: .** : .::*:*: .. * :** * ...... .: ::.:: :*: : .: : * :* : :. :: *.:. ...: :*: . :* .: ** :*: . *:: *.* . : * ** ** .* .* .: :: * . :: *:: :: **: : : *: ::: :: . .: : .: *:: .* * *:. * * *. *. : :**: ..: :: * : *: :::. : : :: :.::: * : *: *** ** *: : :*:.:*.** : *:. : : * :::. : * .*.*** : ::*: . ::* *: :: :*: .. .* ::*: : .* * * .: . :* . :. :* . : ...::. * . *.:: ** : ** . *:* :* ", "identical_positions": 84, "similar_positions": 186, "identity": "7.13%" }, { "cls_id": "homologset.agr.SGD:S000001686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42346-1", "uniprot_id": "MTOR_RAT", "id": "P42346-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "----------------------------------------------------------------MLGTGPATATAGAATSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNSTR---IGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRN--------EGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYS-SHQGLMGFGASPSPTKSTLVESRCCRDLMEEKFDQVCQWVLKCRSSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK-------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---MPKGLAHQLASPGLT-TLPEASDV-------ASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIR-MEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFVIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQ-SPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSSQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQH------AIATEDQQ-----HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTTATTAASAAAATSTEGSNSESEAESNESSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNAKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLN9-1", "uniprot_id": "MTOR_MOUSE", "id": "Q9JLN9-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "----------------------------------------------------------------MLGTGPAVATASAATSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNSTR---IGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRN--------EGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQPNALVGLLGYS-SPQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRSSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK-------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---MPKGLAHQLASPGLT-TLPEASDV-------ASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIR-MEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQ-SPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSSQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKEDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTAHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQH------AIATEDQQ-----HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAASAAAATSTEGSNSESEAESNENSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKAGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42345-1", "uniprot_id": "MTOR_HUMAN", "id": "P42345-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "----------------------------------------------------------------MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATR---IGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRN--------EGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYS-SHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK-------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---MPKGLAHQLASPGLT-TLPEASDV-------GSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIR-MEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQ-SPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHP-LPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQH------AIATEDQQ-----HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NB07-1", "uniprot_id": "A0A8M1NB07_DANRE", "id": "A0A8M1NB07-1", "name": "Serine/threonine-protein kinase TOR", "aln": "------------------------------------------------------------------------------MSGTATVLQQFVSGLKSRNEDTRAKAAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEGGNATR---ISRFANYLRNLLPSSDSVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGADRN--------EGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDSKQAIREGAVSALRACLILTTQRE-TKEMQKPQWYKQTFEEAEKGFDETLAK---EKGMNKDDRVHGALLILNELVRISSMEGERMREEMEEITQQQLVHDKYCKELMGFSTKPRHITPFTSFQSVQPQQSNALLGLLGYS-TPQGFLSFGAAPVPSKSTLVESRYCRELMEERFDQVCRWVLKYRTSKNPLIQMTILNLLPRLAAFQPHTFTD-QYLQDTMGHLLGCLK-------KEKERTAAFQALGLLVVAVRADIQPYLSKILEIIKAALPPKDFAHKRQKTMQVDATVFTCISMLSRAMGPSIQQDV-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---MPKGLAYQLSSPSLT-NIPEASDV-------GSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIR-MEAARTCSRLLTPSIHLLSGHGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDP--NPGVVICVLATIGELAQVSG--LEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVIRVCDASIREFLFQQMGMVVCFVKIHIRPYMDDIFTLIREYWTPNNPMQNTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDMSVGRNVTIKLLMAIQLFGANLDDYLHLLLPPVVKLFDAPDVPLQARKVALETLDRLTESLDFTDYASRIIHPIVRTLDV-TPELRNSSMDTLSSLVFQLGKKYQIFIPMVNKVMLKHRINHQRYDVLICRIVKGYTLAEEEEDPLIFQHRQLRSSQSDTLVSGPVESGPMKKLHVSTTALQKAWGAARKVSKDDWLEWLRRLSVVLLKESSSPALRSCWSLAQTYIPLARDLFNAAFLSCWSELSEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGASPLILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKIDMNKDDPELILGRMRCLEALGEWGQLHQQCCEEWTLVSEETQAKMARMAAAAAWGLGHWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYKLVP---ERRDIIRETWWERLQGCQRIVEDWQRILMVRSLVINPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSKQLDHP-LPTAHPHVTYAYMKYMWKSTRKIDAFQHMQHFVQGMQQQAQH------AIAAEDQQ-----HKLELHKLMARCFLKLGEWQLSLQG-INESTIPKVLQYYSHSTEHDRNWYKAWHAWAVMNFEAVLHYKHQNQGRDEKKKLRHASGASAN-----------------SEASNSDSEADSTEHSPVPSPGQKKVNEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK45-1", "uniprot_id": "TOR_DROME", "id": "Q9VK45-1", "name": "Serine/threonine-protein kinase mTor", "aln": "-------------------------------------------------------------------------------MSTTSVVQQFVNGLKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGALAMKCLINCEGSLTARK-GISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSFDFDIKKAFEVLRGERQ--------EYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNADLGSSKDQKGVTRDDRIHGGLVVFNELFRCANATWERRYTSLKTLFP-KTQHNKFLEASSSSSMGSQLNTLVPRLKVPFIDKLGSTQTHLGEGEHHKGVAKFAS------HNVLESAYAQEILQEHYTSICDNVLEQRTSKSPYVQQALLQILPRLAAFNRAVFVE-KYLQTCVSHLMQILRG------KEKDRTVAYITIGYMAVAVQSAIEVHLSSIMTSVKVALPSKDLTSKRK--VPVDPAVFACITLLAHAVKSEIADDV-KDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILP---------YTALPTIAIDGSLMQNGDG-------ATTVLALKTLGTFNFEEQNMLDFVQRCADYFIVHEQQEIR-LEAVQTCTRLLKLAVQ--SSESMENSKTLSDTVSHVIERLLMVAITDMDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLHEPES--NPGVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGK-VDESQDISTAELLVNMGN-ALDEYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTADNNLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQQVSMVALETINNLACQLDFTDFSSRIIHPLVRVLDA-EPELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDPEYEELLSKIKSCSTLADSYG-AGESELRPSRFKNNEPFVTDRNSNN--KNLQVTTNELRTAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQV-TDMPEITQTILNLAEFMEHCDRDPIPIETK----LLGTRAMACRAYAKALRYKEEEFLLREDSQVFESLILINNKLQQREAAEGLLTRYRNAANELNVQGRWYEKLHNWDEALEHYERNLKTDSSDLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIP---ERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLLGTDPKLNPNQP-LPCNQPQVTYAYTKYMAANNQLQEAYEQLTHFVSTYSQELS---------CLPPEA-----LKQQDQRLMARCYLRMATWQNKLQDSIRPDAIQGALECFEKATSYDPNWYKAWHLWAYMNFKVVQAQKS---ALDKQQ----PPGASMG----------------MTMGSGLDSDLMIIQR---------------------YAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSASLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPG-QELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGWCPFW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32600-1", "uniprot_id": "TOR2_YEAST", "id": "P32600-1", "name": "Serine/threonine-protein kinase TOR2", "aln": "MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMSTTSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERASGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISFYLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRTCIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDAKLIIRLDAAVALGKCLTIIQDRD---PALGKQWFQRLFQGCTHGLS-----------LNTNDSVHATLLVFRELLSLKAP----------------------------------------------------------------------------------------YLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTK-KYLDRIMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLR-----TKFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESNDDITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIK------DDICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLLFMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESATLLCTLINSSDEVAKPYIDPILDVILPKCQDASS----AVASTALKVLGELSVVGG--KEMTRYLKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKTENNPHIRRGTVRLIGILGALDPYKH----------REIEVTSNSKSSVEQNAPSIDIALLMQGVSP-SNDEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVMRSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIK-LQITIISVIESISKALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIVVRMTEYSAG--SLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTLSLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVPERKNYEDEMQVT---------KLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDK-PLPIPIH----TLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQLHQTDSAIGILKHAQQHN-ELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKLRSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQSPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQVRIKFANLCRKSGRMALAKKVLNTLLEETD--DPDHPNTAKASPPVVYAQLKYLWATGLQDEALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGSDASSVTDINEFDN--------------GMIGVNTFDAKEVHYSSN---------------LIHRHVIPAIKGFFHSISLSESSSLQDALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGRDLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNAN---ELLSNGAITEEEVQRVENEHKNAIR-------------NARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:: : . *** : : ..:::* :. **:* :: * :.::::** :: . .*: ** **: **. . . * ** *: .* **.:*:.:: :*: : :: .:*::: .:: * : * ***:*::::: ** * :: : .::: *: .: *.* ** .* ** .* : :*: **:: :: . .:. :. :* :*. *:::.**. :.::: .: .:: : * :: : :** **** *.. :**: : * : :: ::.::. ::* : . * : :. ::. :: :: .* * : .: :* ** *: *: . : ..: *::*: *: :* : * *..::*.*:. : . :: :** * : . . . .: : . . : .: : .. .: :**: : :: *...:* : * :* ::. .. * . *:.*:.:**::.*** ::* :* *.. ** :***.:.*. **::*:*::* *: *: :*****:***:*:* **. :::::*:*:.*.: : **:** :* *: .: .: .*::***..:: * ::... .* .* .:*:*: *.* ** : .:*: :::: : * . ** .** **** :::* ** * .** *: :*:*:****:. ** ::*::*:***:***** :: : *... ::: . . : :: .:. . **:**:* : **:*:.* :** :** .:**: .**:.**::** :* *::* :: :* . :* ***:. ::.:** ** .:: .* :::*:: . :* *:* :**.* ** **: ::.: :. :* :: :* * * *. ::* :: **..* * *::* :*:: : . :: *:..*: .::::: :***::.:** *: ** . :* ** * ***..: :*:*::::.: ::** . *: *: :: . *. . : : :.: .: :* *. *:.** ::: :*:** **::***: ***:*.* .**:* :*.. * .: *:****:* *** **. . :::* ::: ** : .*: * :***.***** *: *:*: . ** * *:*:****:*** ** :*:** ***:*:* ::* *:* : **::: *****:.*::** *:.: .... * :*::*.* ***:* :* : .:* *.: . :** ***** .*: : :*. : :: * :* *:*.:*:: *. *: * ::**** :**:::..***.***..:* ::::****:*:** :* ::* :: * ** * *: :: *::*: *:***:.*:** :. :*:*.** *** : *::*.* ** : ::* . * *.** * : . :* ::: :*.. :: . : : :*:***:*: . *: ** . . * : :* .* .****** ** **:.: . :: . .. . . . . :.:**::***:**** ....***:**:***** :* .:. :*: .*.: *:*.***:*:****:**. . :*.: : .** *:*: *****:*** ** ** : :*::** .*:..* *. .**:** : *.****:*:**** *:***::*** :**::*.: ** ****: *::***:**:* **.:::**:* :* :* .* * * :* :***:**:**::*.:***** :*** :*****: .:********: .. : :::*. : . :.**:*******: : **:*::: ::******:***. *****.****** :*. :*::* **:*..****.:***:****:.**:*.***::*: **: ** ** **.:*****:***::***** :*:.:* *:** *:***** *** *::**..**********.******************::**::*********.*: *******:******** ****:*::*.:* **..** *** ::.*:**:****.:***:** : * :. . . * . :. * :* :::*: **** *: . :: **: **:***. ***** ********", "identical_positions": 797, "similar_positions": 798, "identity": "29.85%" }, { "cls_id": "homologset.agr.SGD:S000001688", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT11-1", "uniprot_id": "A0A8I5ZT11_RAT", "id": "A0A8I5ZT11-1", "name": "Exportin-T", "aln": "----MDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQKTYSDDHVKFFCFQVLEHQVKYKYSELSTAQQQLIRGTLLSWLQAQMLNPQPEKT--FIRNKAAQVFALLFVTEY----LTKWPKFFFDILSVVDLN--------------PRGVDLYLRILMAIDSELVDRDVVHTSEEA-RRNTLIKDTMREQCIPNLVESWYQILHNYQYTN---SEVLCQCLEVVGAYVSWIDLSLIANDR--FINMLLGHMSVEVLREEACDCLFEIVNKGMDPVDKMKLVESLCQVLQTAGFFSIDQE-------EDLDFVARFSKLVNGMGQSLIVSWTKLIKNG-------AVKNAQEALEAIETKVPLMLQLLVHEDDDISSNIIGFCYDYLHILKQLSVLSD----QQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELVLASVRRVFSATLQNWQTTRFMEVEVAVRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTL-----VTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIP----------CVLMAFLDHRGLWHSSAKVRSRTAYLFSRFVKSLNKQMN-------PYIEDILNRIQDLLALSPPENGYQSLLSS----DDQLFIYETAGALIVNSEYPAEHKQA---------LMKDLLTPLMERFKVLLEK-------LMMAQDEERQVSLADSLNHAVGFASRTSKAFSNKQTVKQCGCSQVYLDCLQTFLPALSCPLQKDVLRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAK--DLQEFIPLINQITAKFKMQVS--PFLQQMFMPLLHAIFEVLLRPAEDNDQ------------------------SAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVERVLVT--VIQGAVEYPDPTAQKTCFIILSKLVELWGGKDGP-------------AGFADFVYKHIVPACFLAPLK--QTFDLADAQTVLALSECAVTLKTIHLKRGP------ECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRT8-1", "uniprot_id": "XPOT_MOUSE", "id": "Q9CRT8-1", "name": "Exportin-T", "aln": "----MDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQKTYSDDHVKFFCFQVLEHQVKYKYSELSTAQQQLIRETLLSWLQAQMQNPQPEKT--FIRNKAAQVFALLFVTEY----LTKWPKFFFDILSVVDLN--------------PRGVDLYLRILMAIDSELVDRDVVHTSEASGLENTLIKDTMREQCIPNLVESWYQILHNYQYTN---SEVLCQCLEVVGAYVSWIDLSLIANDR--FINMLLGHMSVEVLREEACDCLFEIVNKGMDPVDKMKLVESLCQVLQTAGFFSIDQE-------EDLDFVARFSKLVNGMGQSLIVSWTKLIKNG-------AVKNAQEALEAIETKVPLMLQLLVHEDDDISSNIIGFCYDYLHILKQLPVLSD----QQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELVLASVRRVFSATLQNWQTTRFMEVEVAVRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTL-----VTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIP----------CVLMAFLDHRGLWHSSAKVRSRTAYLFSRFVKSLNKQMN-------PYIEEILNRIQDLLALSPPENGYQSLLSS----DDQLFIYETAGALIVNSEYPAENKQA---------LMKDLLTPLMERFKVLLEK-------LMMAQDEERQASLADSLNHAVGFASRTSKAFSNKQTVKQCGCSQVYLDCLQTFLPALSCPLQKDVLRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAK--DLQEFIPLINQITAKFKMQVS--PFLQQMFMPLLHAIFEVLLRPAEDNDQ------------------------SAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVEQVLVT--IIQGAVDYPDPIAQKTCFIILSKLVELWGGKDGP-------------VGFADFVYKHIVPACFLAPLK--QTFDLADAQTVLALSECAVTLKTIHLKRGP------ECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43592-1", "uniprot_id": "XPOT_HUMAN", "id": "O43592-1", "name": "Exportin-T", "aln": "----MDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEHQVKYKYSELTTVQQQLIRETLISWLQAQMLNPQPEKT--FIRNKAAQVFALLFVTEY----LTKWPKFFFDILSVVDLN--------------PRGVDLYLRILMAIDSELVDRDVVHTSEEA-RRNTLIKDTMREQCIPNLVESWYQILQNYQFTN---SEVTCQCLEVVGAYVSWIDLSLIANDR--FINMLLGHMSIEVLREEACDCLFEVVNKGMDPVDKMKLVESLCQVLQSAGFFSIDQE-------EDVDFLARFSKLVNGMGQSLIVSWSKLIKNG-------DIKNAQEALQAIETKVALMLQLLIHEDDDISSNIIGFCYDYLHILKQLTVLSD----QQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELLLASVRRVFSSTLQNWQTTRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTL-----VTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIP----------CVLMAFLDHRGLRHSSAKVRSRTAYLFSRFVKSLNKQMN-------PFIEDILNRIQDLLELSPPENGHQSLLSS----DDQLFIYETAGVLIVNSEYPAERKQA---------LMRNLLTPLMEKFKILLEK-------LMLAQDEERQASLADCLNHAVGFASRTSKAFSNKQTVKQCGCSEVYLDCLQTFLPALSCPLQKDILRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAK--DLQEFIPLINQITAKFKIQVS--PFLQQMFMPLLHAIFEVLLRPAEENDQ------------------------SAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVERVLVT--VIQGAVEYPDPIAQKTCFIILSKLVELWGGKDGP-------------VGFADFVYKHIVPACFLAPLK--QTFDLADAQTVLALSECAVTLKTIHLKRGP------ECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPJ8-1", "uniprot_id": "XPOT_DANRE", "id": "Q5SPJ8-1", "name": "Exportin-T", "aln": "----MDEQALMGLNPNADACYRQRALAYFEQLKASLDGWEVCAEALAKGVYSDDHVKFFCFQVLEHQIKFRHGSLSAAQQQLIRETLMKWLQTQLMNVHPEKP--FIRNKAAQVFALTFVMEY----LTLWPKFFFDVLALVGLN--------------PNGVDIYLRTLMAIDAEVVDRDILHSPEET-RRNTLIKDGMREQCIPALVESWFQILQTYQHTH---SELTCQCLEVVGAFVSWIDLNLIANDR--FVNLLLSHMSMEELREAACDCLFEIVNKGMDPVDKTKLVESLCQVLQSAGFFNVEQE-------EDVDFLAKFSRLVNGMGQSLVLSWTKLSKTA-------DEKISAETLRAVESKVPLMLQLLIHEDDDISANIVCFCYDYLHVLKQLPALNE----QQKSNVEAIMLAVMSKLKYDDEYNFENEGEDEAMFVEYRKQLKMLLDRLAQVSPELLLEAVHRVFNATMQSWQTLQFMEVEVSIRLLYMLGEALPASHGAHFSGDSAKTSTLQAMMRTL-----VSCGVSEYQHSSVTLEFFETVVRYDKFFLVEPQHIP----------AVLMAFLDHRGLRHSSPKVRSRVAYLFSRFIKTLHKHMN-------AFIEDILSRIQDLLELAPPENGFPALLSS----DDQLFMFETAGVLIVNGESPAERKQG---------LMRGLLSPLMEAFRMLLEK-------LPLEPDEERQTALADCLSHAVGFASRTSKAFSNKQTVKQCGCSEVYLDCLQTFLPALSCPVQRGALRSAVRSFLHRMIICLEEEVLPFIPAASQHMLKDCEAR--DLQEFIPLISQITAKFKNQVS--PFLQEIFMPLVMSIFEVLSRPAEENDQ------------------------TAALEKQMLRRSYFSFIQTIASSSSSQVMASQGAENIERVLFT--IIQGAVDFPDPVAQKTCFIILSRLVELWGGKDGL-------------VGFPDFIYKHIIPACFMAPLK--TTFDLSDAQTVLTLSECSLTLHMIHLKRGP------ECLQFLQ-EYLPSLHVSPEITQELCQVLQQPDVKVLKNYMKVFFQQAKL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33418-1", "uniprot_id": "XPOT_YEAST", "id": "P33418-1", "name": "Exportin-T", "aln": "MLERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFISLVIN-ENSNDLLKFYGLSTLIELMTEG-VNANPNGLNLVKFEITKWLKFQVLGNKQTKLPDFLMNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLGLEFFNKLCLMINSEIADQSFIRSKESQ-LKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQIVSQCPGLINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILAIISKKMKPMDKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGIEFTIIIEQVNDDQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFWSNYLAFLKKYKASSPNFVPLHKDFLDNFQQICFKRMKFSDDE--VTQDDFEEFNETVRFKLKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYFGLNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSANTANATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFANKNLVNEITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELTAATANTPIDYDILDQILTPLFTQLEGCITQGASPVVILECHHILMAIGTLARGLHIGLVPENQVNNMVVNKKLINDS-LIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPILSNKILPFINKLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPLINKVHSIIEEIDEQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFLQSFTNNSVTSILLSDINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGNGTCLDNDDINKDPNLKIDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLARLLRELFIVSSNPTTNENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWFVDNFISVLKQGQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . :*.:* :::*: :: :* * :. :: . : : *:* :**: :..* . :. . .. :*:: : .**: *: . : * *: ** ::*:: *: * . * .** *::::. :: *:::: : : *::*:.*:..::: * .*. *** **:: * * : *:* *: : . : . *: :*:::****:.** : . ::::: .:.:: : . :*:: ::.* *.*:** ::: : . : : :.. . ::::. :::*:..:* .: : :: . : :*. :.::*::: :* *.*::: . * :** .**: . . :* :: : :.::.:.:: .:.: * : * :** : : :. :.*.*.* : : :.:.: . :. : .*::: :: *.*. .: . ..: .:.. ::* * :. : :: .: : *:* :*: :*: . : . :* *:. .: :. :** * ***:**:* . ::: :::* .:*. ** : .. . . .. *:**:::* * :*. .: . * . . :: :*:**: :. : : * :** * .: .:..: . **: :::. . : : :.:* ::* : :*.. * : *:* *.:::**** : :*.. : : :: :*: ::.*: *: :.. :::::: **: :..:: . *::** : :* :*:::* :*:*:.:... :.:: .: . : *:.. : . : :. *..: :*..::: :*. *: ::. : :* * *:: .*:: :.: : : *: :.: . **:::* ***.:::. *: :: : * . * ::::: * . ", "identical_positions": 160, "similar_positions": 430, "identity": "14.47%" }, { "cls_id": "homologset.agr.SGD:S000001689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EST4-1", "uniprot_id": "PSMG2_MOUSE", "id": "Q9EST4-1", "name": "Proteasome assembly chaperone 2", "aln": "-MFVPCGESVPDLTNFTLLMPAVSVGNVGQLAIDLIISTLN--MCKIGYFYTDCLVPMVG------NNPYATEEENSNELSINTEVYSLPSKKLVVLQLRSIFIKYKSKS--FCEKLLAWVESSGCARIIVLSSSHSYHRNDAQLRSTPFRYLLTPCLQKSVQNKIKSLNWLEME-KSRCIPEMSDSEFCIRIPGGG-ITKTLYDESCSKEIQMAV-LLKFVSEGDNIPDAVSLVEYLNEWLQIIKPCNDGPMASALPWKIPSSWRLLFGSGLPPALF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969U7-1", "uniprot_id": "PSMG2_HUMAN", "id": "Q969U7-1", "name": "Proteasome assembly chaperone 2", "aln": "-MFVPCGESAPDLAGFTLLMPAVSVGNVGQLAMDLIISTLN--MSKIGYFYTDCLVPMVG------NNPYATTEGNSTELSINAEVYSLPSRKLVALQLRSIFIKYKSKP--FCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEME-KSRCIPEIDDSEFCIRIPGGG-ITKTLYDESCSKEIQMAV-LLKFVSEGDNIPDALGLVEYLNEWLQILKPLSDDPTVSASRWKIPSSWRLLFGSGLPPALF-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXS2-1", "uniprot_id": "PSMG2_DANRE", "id": "Q1LXS2-1", "name": "Proteasome assembly chaperone 2", "aln": "-MFISSGDAVPSFKGFTLILPAVSVGNVGQLAVDLLISTLN--MPRVGYFHTDCLIPMAG------NNPYASSTEDAAQLSTSAEVYSHRDLKLAVLQIRAPIIQTKVKS--FRKLMISWMKSSGFLRTVLLSSAHAYQRDDQQLHGTPLRYMLSPSLEKEERQRFEELGWREME-KISVFPGISDSEQRLYIPGGG-VTKCLYTDCCTEDVPMAV-VLIFCSEGDNIPDAFALINCLNDWLHLL----EKPTQGSVQWRVPPSWKLLFGSGIPPLLF-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEC2-1", "uniprot_id": "Q9VEC2_DROME", "id": "Q9VEC2-1", "name": "Proteasome assembly chaperone 2", "aln": "MLFLKDKRTTLDVAEHTVIIPSICVGNAAQLACDLLIASKE--LRRIGSITHPALIPVYG------PSAYQHE---PKEKVSSCELYEGTEDKLLVVQFRAPWVARHTAH--FQKELVELLK--GARRVVILSGSFGFEKR--VIEESPWAYRASENFKEAHAAQLGNEELIKWK-EHKGD----------AIYGGG-NALQLFKAFDEQKVPVML-LFRYLLEGDNSTDASLIVRELNELCEDFLQLRNGGDG-SFKLTVPKSWNLLFGNDVTELLF-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36040-1", "uniprot_id": "POC2_YEAST", "id": "P36040-1", "name": "Proteasome assembly chaperone 2", "aln": "--------------MSCLVLPLVSVGNIPQLSIDWLLNSQANEWEYLEALDSKYLVEFVGPLDRPEDGSDSLYKDADMKYSSALEVFYNKKRGLFAIQQRTPLVSVNYLNNFIVEIILPFLSKYNISEICIWDSLYAMEDENGVIVRPQEVYSLGEFYFDDEAELLSNLHLNDQESMVNNWLHFTPTSFQDKISVDQPIFKILFQILNASQRPKALRSIKYCSCLANEGDNSLDSQQFLQWIISQKVIKNAPPI--VKFVRPISWQGAYGMADARDKFVDLYN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* :.*** **: * :: : : : *: . * .. : *:: . * .:* *: : : : : :: :. . . : .. .. . : . * . : . . : * . *: .. : : : * * . : : : * **. :* . * ", "identical_positions": 23, "similar_positions": 59, "identity": "8.13%" }, { "cls_id": "homologset.agr.SGD:S000001690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99KI3-1", "uniprot_id": "EMC3_MOUSE", "id": "Q99KI3-1", "name": "ER membrane protein complex subunit 3", "aln": "MAGPELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQ---SDKKLTQEQVSDSQVLIRSRVLRENGKYIPKQSFLTRKYYFNN--PEDGFFKKTKRKV-----VPPSPMTDPTM---LTDMMKGNVTNVLPMILIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMARDLHFEGMFKKELQTSIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2V8-1", "uniprot_id": "EMC3_RAT", "id": "Q5U2V8-1", "name": "ER membrane protein complex subunit 3", "aln": "MAGPELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQ---SDKKLTQEQVSDSQVLIRSRVLRENGKYIPKQSFLTRKYYFNN--PEDGFFKKTKRKV-----VPPSPMTDPTM---LTDMMKGNVTNVLPMILIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMARDLHFEGMFKKELQTSIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0I2-1", "uniprot_id": "EMC3_HUMAN", "id": "Q9P0I2-1", "name": "ER membrane protein complex subunit 3", "aln": "MAGPELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQ---SDKKLTQEQVSDSQVLIRSRVLRENGKYIPKQSFLTRKYYFNN--PEDGFFKKTKRKV-----VPPSPMTDPTM---LTDMMKGNVTNVLPMILIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMAKDLHFEGMFKKELQTSIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXW4-1", "uniprot_id": "EMC3_DANRE", "id": "Q7SXW4-1", "name": "ER membrane protein complex subunit 3", "aln": "MAEPELLLDSNIRLWVVLPIVFITFLVGVIRHYVSILLQ---SDKKLTLEQVSDSQVLIRSRVLRENGKYIPKQSFLMRKFYFNN--QEDGFFKKTKRKV-----VPPSPMTDPSM---LTDMMKGNVTNVLPMILIGGWINWTFSGFVTTKVPFPLTLRFKPMLQQGIELLSLDASWVSSASWYFLNVFGLRSMYSLILGQDNGADQSRIMQEQMSGAAMAMPADTNKAFKAEWEALELTDHQWALENVEEDLMSKDLDLSGMFSKDLPTGIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKR0-1", "uniprot_id": "Q9VKR0_DROME", "id": "Q9VKR0-1", "name": "ER membrane protein complex subunit 3", "aln": "MT--ELLIDPDIRVWVFLPIVLITFLVGIVRHYVSILIS---TQKKAEITQIQDSQAMIRARLLRENGKYLSAQSFSMRKNYFNN--EETGYFKTQKR--------APVAQNSSAM---LTDMVKGNFINVLPMVVIGGWINWMFSGFVTTKVPFPLTLRFKPMLQRGVELASLDAAWVSSASWYFLNVFGLRSIYTLVLGENNHADQTQAQADAMTGAAMTMPQDPKAAFKAEWEALEITEYHNALKNIDADMLA-------IASAPAASS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36039-1", "uniprot_id": "EMC3_YEAST", "id": "P36039-1", "name": "ER membrane protein complex subunit 3", "aln": "-----MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPRVKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEVPNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMG-IQAGIGGPQGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* ::: **.*** :: .:.*::::*: *: ::: :: : * : :::* ** :. ::* :* :: : * .: . *: * . ...:* : :* ***. ..:* :* *:* *:**: ::***** :** *** *: **. **** ****:.*:**..:*.*: ::: . : *. . : . *::: : * : ::. .*.::: :: ", "identical_positions": 61, "similar_positions": 91, "identity": "22.26%" }, { "cls_id": "homologset.agr.SGD:S000001692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5X0E4-1", "uniprot_id": "ABCB5_MOUSE", "id": "B5X0E4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "----------MANSERTNGLQET-------------NQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLING-------CLVQTNRTKYQNCSQTQEKLNEDIIV-----------------LTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILA-QDISWFDGSD-ICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG--------YTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFST--AGFVPEC-IEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGE----------KEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAK-----QGLYYSLAMAQDIKK----------------VDEQMESRTCSTAGNASYGSLCDVNSAKA------PCTDQLEEAVHHQK-----------------------TSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVT-MFE-DKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILIS--FIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKP-TINSC---------SQSGEKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRM-VPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEL4-1", "uniprot_id": "D4AEL4_RAT", "id": "D4AEL4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "----------MAHSERANGLQES-------------NQRYGSLQEQLPKAGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHFING-------CLVQTNKTKYQNCSQSQEKLNEDIIM-----------------LTLYYVGIGAAALVLGYVQISFWVITAARQTTRIRKQFFHSILA-QDISWFDGTD-ICELNTRMNGDISKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLAILSTSPLIMAASALCSRMVISLTSKELDAYSKAGAVAEEALSSIRTVTAFGAQEKEIQRYTQNLKDAKDAGIKRAIASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG--------YTVGTILAVFFSVIHSSYCIGSVAPHLETFTIARGAAFNIFHVIDKKPNIDNFST--AGYKPES-IEGNIEFKNVSFSYPSRPSAKILKGFNLKIKSGETVALVGPSGSGKTTTVQLLQRLYDPEEGCITVDENDIRTQNVRHYREQIGVVSQEPVLFGTTIGNNIKFGREGVSE----------EEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQAALEKASKGRTTLVVAHRLSTIRGADLIVTMKDGEVVEKGIHAELMAK-----QGLYYSLAVAQDIKK----------------VDEQMESRTCSAAGNASNGSLCNVNSAKS------PCTDQFEEAVPHQK-----------------------TTLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPAFSIIFGKLVT-MFE-DKNKTTLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEEILAMRLRHSAFKAMLYQDMAWYDEKDNSTGALTTTLAVDVAQIRGAATSRLGIITQDVTNMSLSILIS--FVYGWEMTLLILSFAPILAVTGMIQTAAMAGFANKDKQELKRAGKIATEAVENIRTVVSLTREKAFEHMYEETLRTQHRNALKRAHITGSCYAVSHAFVHFAHAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGAAHLFALLKNKP-SIDSC---------SQNGEKPDACEGNLEFREVSFFYPCRPEVPVLQDMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRM-VPLEEIKEVADAANIHSFIEGLPGKYSTQVGLRGMHLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKMVQQALDKARRGRTCLVVAHRLSTIQNADMIVVLQNGRIKEQGTHQELLRNGETYFKLATAH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3G0-4", "uniprot_id": "ABCB5_HUMAN", "id": "Q2M3G0-4", "name": "ATP-binding cassette sub-family B member 5", "aln": "----------MENSERAEEMQEN-------------YQRNGTAEEQ-PKLRKEAVGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISG-------CLVQTNTTNYQNCTQSQEKLNEDMTL-----------------LTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLA-QDIGWFDSCD-IGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPG--------YTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFST--AGYKPES-IEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTD----------EEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAK-----RGLYYSLVMSQDIKK----------------ADEQMESMTYSTERKTNSLPLHSVKSIKS------DFIDKAEESTQSKE-----------------------ISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIIT-MFG-NNDKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIIS--FIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKP-NIDSR---------SQEGKKPDTCEGNLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-------LFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRV-VPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQSVQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06795-1", "uniprot_id": "MDR1B_MOUSE", "id": "P06795-1", "name": "ATP-dependent translocase ABCB1", "aln": "----------MEFEENLKGRADK----------NFSKMGKKSK--KEKKEKKPAVGVFGMFRYADWLDKLCMILGTLAAIIHGTLLPLLMLVFGNMTDSFTKA-EASILP-SITNQSGPNSTLIISNSSLEEEMAI-----------------YAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNE----------YSIGEVLTVFFSILLGTFSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFST--KGYKPDS-IMGNLEFKNVHFNYPSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMRE-----KGIYFKLVMTQTRGNEIEPG--------NNAYGSQSDTDASELTSEESKSPLIR-RSIYRSVHRKQDQERRLSMK-EAVD-----------------------EDVPLVSFWRILNLNLSEWPYLLVGVLCAVINGCIQPVFAIVFSRIVG-VFSRDDDHETKRQNCNLFSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNVANLGTGVILS--LVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIRIIEKTP-EIDSY---------STEGLKPTLLEGNVKFNGVQFNYPTRPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRA-VSHEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43245-1", "uniprot_id": "MDR1_RAT", "id": "P43245-1", "name": "ATP-dependent translocase ABCB1", "aln": "----------MEFEEGLNGRADK----------NFSKMGKKSK--KEK-EKKPAVGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPS-RDPHSDRAITNQSEINSTHTVSDTSLEEDMAM-----------------YAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVND-AGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNE----------YSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFST--KGHKPDS-IMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKE-----KGIYFKLVMTQTRGNEIEPG--------NNAYESQSDTGASELTSEESKSPLIR-RSIRRSIHRRQDQERRLSSK-EDVD-----------------------EDVPMVSFWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVG-VFSRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIGIIEKIP-EIDSY---------STEGLKPNWLEGNVKFNGVKFNYPTRPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTV-------FLDGKEIKQLNVQCVRA-LGIVSQEPILFDCSIAENIAYGDNSRV-VSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08183-1", "uniprot_id": "MDR1_HUMAN", "id": "P08183-1", "name": "ATP-dependent translocase ABCB1", "aln": "----------MDLEGDRNGGAKKK---------NFFKLNNKSE--KDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMN--LEEDMTR-----------------YAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMR-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE----------YSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSK--SGHKPDN-IKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKE-----KGIYFKLVTMQTAGNEVELE--------NAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTK-EALD-----------------------ESIPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIG-VFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIIS--FIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTP-LIDSY---------STEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKV-------LLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRV-VSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTKRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21447-1", "uniprot_id": "MDR1A_MOUSE", "id": "P21447-1", "name": "ATP-dependent translocase ABCB1", "aln": "----------MELEEDLKGRADK----------NFSKMGKKSK--KEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVS---KNSTNMSEADKRAMFAK--LEEEMTT-----------------YAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE----------YSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSK--SGHKPDN-IQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMRE-----KGIYFKLVMTQTAGNEIELG--------NEACKSKDEIDNLDMSSKDSGSSLIRRRSTRKSICGPHDQDRKLSTK-EALD-----------------------EDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVG-VFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIIS--LIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTP-EIDSY---------STQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRV-VSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21440-1", "uniprot_id": "MDR3_MOUSE", "id": "P21440-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "----------MDLEAARNGTARR--------LDGDFELGSISNQGREKKKKVNLIGLLTLFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKFVDN------TGNFSLPVNFSLSMLNPGRILEEEMTR-----------------YAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILR-QEMGWFDIKG-TTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE----------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE--RGHKPDN-IKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTM----------DEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKK-----EGIYFRLVNMQTAGSQILSE--------EFEVELSDEKAAGDVAPNGWKARIFR-NSTKKSLKSP--HQNRLDEETNELD-----------------------ANVPPVSFLKVLKLNKTEWPYFVVGTVCAIANGALQPAFSIILSEMIA-IFGPGDD-AVKQQKCNMFSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIIS--FIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGHASSFAPDYAKAKLSAAYLFSLFERQP-LIDSY---------SGEGLWPDKFEGSVTFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------LLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRV-VPHDEIVRAAKEANIHPFIETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMVNIQAGTQNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21439-1", "uniprot_id": "MDR3_HUMAN", "id": "P21439-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "----------MDLEAAKNGTAWRPTS-----AEGDFELGISSKQKRKKTKTVKMIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDT------AGNFSFPVNFSLSLLNPGKILEEEMTR-----------------YAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILR-QEIGWFDIND-TTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE----------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE--RGHKPDS-IKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTM----------DEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKK-----EGVYFKLVNMQTSGSQIQSE--------EFELN--DEKAATRMAPNGWKSRLFR-HSTQKNLKNSQMCQKSLDVETDGLE-----------------------ANVPPVSFLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIA-IFGPGDD-AVKQQKCNIFSLIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIIS--FIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQP-LIDSY---------SEEGLKPDKFEGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRV-VSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTQNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QY30-1", "uniprot_id": "ABCBB_MOUSE", "id": "Q9QY30-1", "name": "Bile salt export pump", "aln": "MSDSVILRSVKKFGEENHAFESDG----------FHNNDKKSRLQDKKKGEGARVGFFELFRFSSSKDNWLMFMGSVCALLHGMAQPGMIIVFGILTDIFVEYDIERQ-ELSIPEKVCMNNTIVWINSSFNQNMTN--GTSCGLVDINSEVIKFSGIYAGVGVAVLILGYFQIRLWVITGARQIRKMRKFYFRRIMR-MEIGWFDCTS-VGELNSRFSDDINKIDEAIADQMALFLQRLSTALSGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSRLVLDEGE---------YTPGTLIQIFLCVIIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPVMDCMSG--DGYKLDR-IKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGETTAFVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRLGREEATM----------EDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLLDMATSALDNESEAKVQGALNKIQHGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEELLER-----KGVYFMLVTLQSQEDNTHKE---TGIKGKDTTEGDTPERTFSR-GSYQDSLRASIRQRSKSQLSHLSHEPPLAIGDHKS--SYE-DRKDNDVLV---------EEVEPAPVRRILKYNISEWPYILVGALCAAINGAVTPIYSLLFSQILK-TFS-LVDKEQQRSEIYSMCLFFVILGCVSLFTQFLQGYNFAKSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIFVAVLIA--FLFNWKLSLVISVFFPFLALSGAVQTKMLTGFASQDKEILEKAGQITNEALSNIRTVAGIGVEGRFIKAFEVELEKSYKTAIRKANVYGLCYAFSQGISFLANSAAYRYGGYLIVYEDLNFSYVFRVVSSIAMSATAVGRTFSYTPSYAKAKISAARFFQLLDRKP-PIDVY---------SGAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVDPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTV-------MIDGHDSKKVNVQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKE-ISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQLALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGVVIEKGTHKKLMDQKGAYYKLVITGAPIS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70127-1", "uniprot_id": "ABCBB_RAT", "id": "O70127-1", "name": "Bile salt export pump", "aln": "MSDSVILRSVKKFGEENHAFESDG----------SHNNDKKSRLQDKMKEGDIRVGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQ-ELEIPGKACVNNTIVWINSSFHQNMTN--GTVCGLVDIESEMIKFSGIYAGVGMTVLILGYFQIRLWVITGARQIRRMRKIYFRRIMR-MEIGWFDCTS-VGELNSRFADDIEKINDAIADQLAHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSTLVLDEEE---------YTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTIDRQPVIDCMSG--DGYKLDR-IKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGREDATM----------EDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLER-----KGVYFMLVTLQSQGDNAHKE---TSIMGKDATEGGTLERTFSR-GSYRDSLRASIRQRSKSQLSLLTHDPPLAVADHKS--SYK-DSKDNDVLV---------EEVEPAPVRRILKYNIPEWHYILVGSLSAAINGAVTPIYSLLFSQLLG-TFS-LLDKEQQRSEIHSMCLFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIA--FFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATAVGRTFSYTPSYAKAKISAARFFQLLDRKP-PINVY---------SEAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTV-------MIDGHDSKKVNIQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKE-ISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITGAPIS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95342-1", "uniprot_id": "ABCBB_HUMAN", "id": "O95342-1", "name": "Bile salt export pump", "aln": "MSDSVILRSIKKFGEENDGFESDK----------SYNNDKKSRLQDEKKGDGVRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQ-ELQIPGKACVNNTIVWTNSSLNQNMTN--GTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMR-MEIGWFDCNS-VGELNTRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFWYGSTLVLDEGE---------YTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPIIDCMSE--DGYKLDR-IKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATM----------EDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLER-----KGVYFTLVTLQSQGNQALNE---EDIK--DATEDDMLARTFSR-GSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKS--TYEEDRKDKDIPVQ--------EEVEPAPVRRILKFSAPEWPYMLVGSVGAAVNGTVTPLYAFLFSQILG-TFS-IPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIA--FSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQP-PISVY---------NTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKV-------MIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKE-IPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTGSPIS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNN7-1", "uniprot_id": "A0A8M1RNN7_DANRE", "id": "A0A8M1RNN7-1", "name": "Bile salt export pump", "aln": "MPGTVKLRSVKRFGQENDGFEFSDEETSGDYMTMASGKDNKSKK-SKKEESAIRVGFFQLFRFASCREIWMMVFGSLCAIAHGSAQPLMLLVFGMLTDTFIDYDIELN-ELSDPQKACVNNTIQWRNLTQEENLAQNMTRSCGLLDIEYEMTNFAYYYVGIGAGVFILGYLQISLWITAAARQIQIIRKMYFRKVMR-MEIGWFDCTS-VGELNTRMSDDINKINDAIADQVGIFIQRFTTFVCGFLMGFARGWKLTLVIISVSPLIGIGAGLMALFVAKLTGMELQAYAKAGAVADEVLSSVRTVAAFGGEKKEVDRYDRNLISAQQWGIRKGLIMGFFTGYMWFIIFLCYALAFWYGSSLVVDTQE---------YSPGTLLQVFFGVLIAALNLGQASPCLEAFAAGRGAATIIFETIDREPEIDCLSE--AGYKLDK-VKGDLEFHNITFHYPSRPEVKILDQLNLQVKSGETTAFVGPSGAGKSTAIQLIQRFYDPKEGMLTLDGHDIRGLNIQWLRSLIGIVEQEPVLFATTIAENIRYGRPGVSN----------DDIITAAKEANAYNFIMDLPQKFETLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNESEAVVQEALDKVRMGRTTISIAHRLSTIKNADVIVGFEHGRAVERGKHDELLER-----KGVYFTLVTLQSQGDKALNQKAQQEMEEAECCESDAERRSLNRAGSYRASLRASIHQRSRSQLSNAVPESSVAIAGELGPRSYSETTVLQEFMGKSGVPEDTAEEVEPAPVARILKYNAPEWPYMFFGSIGAAVNGGVNPVYSLLFSQILA-TFS-MPDPVEQRREINGICLFFVVVGLVSFFTQMLQGYAFSKSGELLTRRLRRLGFHAMLGQEIGWFDDRKNSPGALTTRLATDASQVQGATGSQIGMIVNSLTNIGVAVIIS--FYFSWKLTLVILCFLPFLALSGGFQAKMLTGFAKQDKEAMETAGQISGEALNNIRTIAGLGKERNFVEMFETQLEAPYQAALKKANVYGACYGFAQCVVFMANSASYRFGGYLVYHEGLHFSFVFRVISAIVTSGTALGRASSYTPDYAKAKISAARFFQLLDRIP-KISVY---------SKDGQKWDNFKGDIEFIDCKFTYPSRPDIQVLNGLNVSVKPGQTLAFVGSSGCGKSTSVQLLERFYDPNSGRV-------LIDGRESSQINVAYLRSKIGIVSQEPILFDCSIAENIRYGDNQRE-LSMNDVISAAKKAQLHDFVMSLPEKYDTNVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDKAREGRTCIVIAHRLSTIQNSDIIAVMSRGYVIEKGTHDYLMGLKGAYYKLVTTGAPIS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00748-1", "uniprot_id": "MDR65_DROME", "id": "Q00748-1", "name": "Multidrug resistance protein homolog 65", "aln": "----------MERDEVSTSSSEGK---------SQEEAPMAEGLEPTEP-----IAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYD----------DSISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIR-QDIGWHDLAS-KQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRN----VENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLST--DGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQ----------KEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMAL-----EGAYYNMVRAG--DINMPDEVE-----KEDSIEDTKQKSLALFEKSFETSPLNFEKGQKNSVQFEEPIIKALIKDTNAQSAEAP-PEKPN----------------FFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYA-ALA-EKDPEDALRRTAVLSWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVA--MYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHRLFQILDRKP-KIQSP-----MGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIH------IDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRS-VSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQKDH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRW2-1", "uniprot_id": "Q9VRW2_DROME", "id": "Q9VRW2-1", "name": "Multidrug resistance protein homolog 65", "aln": "----------MTMTETREDVPAAD---------ADEATPAAQKKKKTKEKAQPMVSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVVYSELVAMFIERTLGQGTSSVTIGLSLFGGGKILTNASYEENMQELRK----------DSVSFGILMTLNTLLMLFSGVYYVDAFNRLALKLTVRMRREFFKATLR-QEIGWHDMAK-DQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLSK--AGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQ----------KEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDKACKGRTTLVVSHRLSAIRHAHRIVYIENGKAVEQGTHEELMKL-----EGFYHKMVTVHSYDDSAEELLN-----ELEEVAEIKERKMSYEVEPYQLGTRNSIVSLEKNAEFQMKNLNGLANITMNQEIDDPRVPSAN----------------FISTFFRILGWARPEWSFLIIGAICAGLYGVTMPVFSVVLAELYG-SLA-KPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIA--FPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRHQILSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKP-QIQSPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKIL------IDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQ-VPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSGRTCIVIAHRLSTIQNANVICVIQAGKIVEQGSHSQLLAKNGIYSKLYRCQTKAS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00449-1", "uniprot_id": "MDR49_DROME", "id": "Q00449-1", "name": "Multidrug resistance protein homolog 49", "aln": "----------MVKKEESRLPQAGD---------FQLKEGSVVDATRKYS-------YFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEFTSLLVDRTVGVGTSSPAFALPMFGGGQQLTNASKEENNQAIID----------DATAFGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLR-QDIAWYDTSS-GSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDERD----LPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDE--KGNRPEN-TAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQ----------ADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMER-----RGLYCELVSIT--QRKEATEAD-----EGAVAGRPLQKSQNLSDEETDDDEEDEEEDEEPELQTSGSSRDSGFRASTRRKRRSQRRKKKKDK-----------EVVSKVSFTQLMKLNSPEWRFIVVGGIASVMHGATFPLWGLFFGDFFG-ILS-DGDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVG--FVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFALGQAAPFLAYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTS-TQPNP-----PQSPYNTVEKS---EGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVN------LSG-VPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMALNKIYANLYLMQQVSG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12866-1", "uniprot_id": "STE6_YEAST", "id": "P12866-1", "name": "Alpha-factor-transporting ATPase", "aln": "----------------------------------------------MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAITSILTGR----------------VFDLLSVFVANGSHQGLYSQLVQR------------------SMAVMALGAASVPVMWLSLTSWMHIGERQGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTWSMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGK----------LNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQIESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSIHTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYALKQQKNTESSTG------PQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSFLLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWA--LVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIK-------IDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYG--LQDEILEIEMYDALKYVGIHDFVISSPQGLDTRID--TTLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKDGKVVERGNFDTLYNNRGELFQIVSNQSS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**: : : : * : : . : . . :* : : : *.* : :.:: .. .: . . . .: .*.*:* *. . : * *. : : . : * : :. * :: : . : .:*:* :: . : : : : . : . . :: :. . : . . : * .: * **:* . : ..: . *: . :** .*.**:* :*: *:** * : :: ::: : . * :* *. .** :: :** * : * * ** : . : :. * :****:**:*****:::.. :*:** *.**** . : .: * * : ::*.** : . : :. * * * : :*: * . : : ...* . : * * :. :. . . . : :. . : . . :* : : ::: ::. *. . : : : : .::. :. : . : .: . : .*: ::: *.: * : . : : :::*: : * . : * . : . :* : :: : * . .. : ::.. : * ** : ..:.. : . *: ::* ** **** : ** : *: * : : :* .:* *:* ** :* :*: ** : : . * *: * .* :. ** *: **:.****:::..::*:***.***** *. :: :. . . :.::* ::..: * *. * : *:*.. * .: ", "identical_positions": 143, "similar_positions": 287, "identity": "10.19%" }, { "cls_id": "homologset.agr.SGD:S000001693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U300-1", "uniprot_id": "UBA1_RAT", "id": "Q5U300-1", "name": "Ubiquitin-like modifier-activating enzyme 1", "aln": "MSSSPLSKKRRVSGPDPKPGSNCSSAQSVLSEVSSVPTNGMAKNGSEADIDESLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNSP-LEEQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDE-ARHGFETGDFVSFSEVQGMVQLNGCQPIEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLPASLAEPD-----FVMTDFAKYSRPAQLHIGFQALHQFCAQHN-RPPRPRNEEDATELVTLAQAVNARSPPAVQQDN---VDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPE-DKEALTEDKCLPRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQ--VTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDAR--------------------------MYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTGSQDRA-----AVASLLQSVQVPEFTPKSGVKIHVSDQELQ-SANAS---VDDSRLEELKATLPSPDKLPG-FKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWT-LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02053-1", "uniprot_id": "UBA1_MOUSE", "id": "Q02053-1", "name": "Ubiquitin-like modifier-activating enzyme 1", "aln": "MSSSPLSKKRRVSGPDPKPGSNCSPAQSALSEVSSVPTNGMAKNGSEADIDESLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSSFQVVVLTNSP-LEAQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDE-ARHGFETGDFVSFSEVQGMIQLNGCQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLPASLVEPD-----FVMTDFAKYSRPAQLHIGFQALHQFCALHN-QPPRPRNEEDATELVGLAQAVNARSPPSVKQNS---LDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPE-DKEALTEEKCLPRQNRYDGQVAVFGSDFQEKLSKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQ--VTSHQNRVGPDTERIYDDDFFQNLDGVANALDNIDAR--------------------------MYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTGSQDRA-----AVASLLQSVQVPEFTPKSGVKIHVSDQELQ-SANAS---VDDSRLEELKATLPSPDKLPG-FKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWT-LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22314-1", "uniprot_id": "UBA1_HUMAN", "id": "P22314-1", "name": "Ubiquitin-like modifier-activating enzyme 1", "aln": "MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTP-LEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDE-ARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPD-----FVVTDFAKFSRPAQLHIGFQALHQFCAQHG-RPPRPRNEEDAAELVALAQAVNARALPAVQQNN---LDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPE-DKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIR--VTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDAR--------------------------MYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRA-----AVATFLQSVQVPEFTPKSGVKIHVSDQELQ-SANAS---VDDSRLEELKATLPSPDKLPG-FKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWT-LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LD70-1", "uniprot_id": "A0ABK0LD70_RAT", "id": "A0ABK0LD70-1", "name": "E1 ubiquitin-activating enzyme", "aln": "MSSSVLSKKRRVSGPDSEVDSSWPSTHSVMFGAPPGPNSGMSKN-KEMDIDESLYSRQLYVLGHEAMKHLQTSSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLHEEDIGKNRAEVSQPRLAELNSYVPVHTYTGPLVDDFLSGFQVVVLTNTP-LEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLSAMVSMITKENPGIVTCLEE-TRHGFESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFSICDTSSFSEYTRGGIVSQVKVSQKISFKSLVASLAEPE-----FVITDFAKCCRPAQLHIGFQALHQFCTQHS-RPPRPHNEEDAAEMVTLAQAVNAQSLPAVQQDC---LDIDLIRKLAYVAAGDLAPMSAFIGGLAAQEVMKACSGKFMPIRQWLYFDALECLPE-HRVAFMEDKCLPRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEITVTDMDTIEKSNLNRQFLFRPWDVTKLKSETAAAAVRDINPHIR--VCSHQNRVGPETEHVYDDDFFQNLDGVANALDNVDAR--------------------------LYMDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQSAENVNQYLMDPKFMERTLQLAGTQPLEVLEAIQCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPDQLTSSGVLFWSGPKRCPHPLTFDTNNPLHLDYVMAAANLFAQTYGLEGSQDCA-----AVTTLLQSLPAPKFAPKSGIRIHVSEQELQ-STSAT---VDDSHLEELKTSLPTPDKMLG-FKMHPIDFEKDDDSNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTSAVVGLVCLELYKVVQGHQQLDSFKNSFINLALPFFSFSAPLAPGYHQYYDKKWT-LWDRFDVQGLQPSGEEMTLKQFLDYFKTEHKLEITILSQGVSMLYSFFMPATKLQERLDQPMTEIVSRVSKRKLGQHVKSLVFELCCNNESGDDIEVPYVRYIIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LZP1-1", "uniprot_id": "A0ABK0LZP1_RAT", "id": "A0ABK0LZP1-1", "name": "E1 ubiquitin-activating enzyme", "aln": "MSSSVLSKKRRVSGPDSKVDSSWSSTHSVMFGVPPGPNSGMSKN-KEMDIDESLYSRQLYVLGHEAMKHLQTSSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLHEEDIGKNRAEVSQPRLAELNSYVPVHTYTGPLVDDFLSGFQVVVLTNTP-LEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLSAMVSMITKENPGIVTCLEE-TRHGFESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFSICDTSSFSEYTRGGIVSQVKVSQKISFKSLVASLAEPE-----FVITDFAKCCRPAQLHIGFQALHQFCTQHS-RPPRPHNEEDAAEMVTLAQAVNAQSLPAVQQDC---LDIDLIRKLAYVAAGDLAPMSAFIGGLAAQEVMKACSGKFMPIRQWLYFDALECLPE-HRVAFMEDKCLPRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEITVTDMDTIEKSNLNRQFLFRPWDVTKLKSETAAAAVRDINPHIR--VCSHQNRVGPETEHVYDDDFFQNLDGVANALDNVDAR--------------------------LYMDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQSAENVNQYLMDPKFMERTLQLAGTQPLEVLEAIQCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPDQLTSSGVLFWSGPKRCPHPLTFDTNNPLHLDYVMAAANLFAQTYGLEGSQDCA-----AVTTLLQSLPAPKFAPKSGIRIHVSEQELQ-STSAT---VDDSHLEELKTSLPTPDKMLG-FKMHPIDFEKDDDSNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTSAVVGLVCLELYKVVQGHQQLDSFKNSFINLALPFFSFSAPLAPGYHQYYDKKWT-LWDRFDVQGLQPSGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPATKLQERLDQPMTEIVSRVSKRKLGQHVKSLVFELCCNNESGDDIEVPYVRYIIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31254-1", "uniprot_id": "UBA1Y_MOUSE", "id": "P31254-1", "name": "Ubiquitin-like modifier-activating enzyme 1 Y", "aln": "MSSSVLSKKRKVSGPDSSLDSSWSPTYSVMFGVPPGPTNEMSKN-KEMDIDESLYSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGIAQWADLSSQFCLREEDIGKNRAEISQPRLAELNSYVPVFAYTGPLIEEFLSGFQVVVLTNTP-LEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLSAMVSMITKENPGIVTCLED-SRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFSICDTSSFSEYIRGGIVSQVKVPRKINFKPLLASLAEPE-----FVVTDFAKCCHPAQLHIGFQALHQFCTQHS-RPPRPHNEEDAEELVTLAQSVNAQALPAVQQDC---LDIDLIRKLAYVAAGDLAPMNAFFGGLAAQEVMKACSGKFMPIRQWLYFDALECLPE-HRVAFMEDKCLPHQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEDGEITVTDMDTIEKSNLNRQFLFRPWDITKLKSETAAAAVRDINPHIR--IFSHQNRVGPETEHVYDDDFFQKLDGVANALDNVDAR--------------------------LYVDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQD---PPEKSIPICTLKNFPNAIEHTVQWARDEFEGLFKQSAENVNQYLTDPKFMERTLQLAGTQPLEVLEAIHCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPAQLTSSGALFWSGPKRCPHPLTFDINNPLHLDYVMAAANLFAQTYGLGGSQDCA-----VVAKLLQSLPVPKFAPKSGIRIHVSEQELQ-STSATT--IDDSHLEELKTALPTPDKLLG-FKMYPIDFEKDDDSNFHMDFIVAASNLRAENYGISPADRHKSKLIAGKIIPAIATTTSAIVGLVCLELYKVVQGHQQLESYKNSFINLALPLFSFSAPLAPECHQYYDQEWT-LWDRFDVQGLQPSGEEMTLKQFLDYFKTEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVSCVSKQKLGHHVKSLVFELCCNSDSGDDIEVPYVRYIIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B975-1", "uniprot_id": "A0A8M2B975_DANRE", "id": "A0A8M2B975-1", "name": "E1 ubiquitin-activating enzyme", "aln": "MSSSPLSKKRRVSGSETKTGSHCSSSNSVRTELSHTPANGMAKNGNDAEIDEGLYSRQLYVLGHDAMKRMQSSNVLISGLRGLGVEIAKNVILGGVKSVTLHDQGVAEWKDLSSQFYLREEDLGKNRADVSQPRLAELNSYVPVTSYTGTLTNEYLTKFQVVVLTNSS-LDEQTRIGEFCHSNGIKLIVADTRGLFGQLFCDFGEEMIVFDTNGEQPLSAMISMITKDSAGVVTCLDE-ARHGFESGDYVTFTEVQGMTELNGCDPVEIKTLGPYTFSICDTSSFSDYVRGGIVTQVKMPKKIAFKSLSSSMAEPE-----FLLTDFAKFDRPGQLHVGFQALHAFEKKHS-RLPKPWNQADADELMTLAEEVNAAQTGSAKQEE---LDQAVIKKLACVAAGDLAPVNAFIGGLAAQEVMKACTGKFMPIMQWLYFDALECLPEPEEVILTEEECAPRNCRYDGQIAVFGSKLQELLAKQRYFLVGAGAIGCELLKNFAMMGLASGE-GEVIVTDMDTIEKSNLNRQFLFRPWDVTKMKSETAAAAVKQMNPSVR--ITGHQNRVGPDTEKVYDDDFFECLDGVANALDNVDAR--------------------------MYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFITESYSSSQD---PPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENALQYLTDSKFMERTLKLPGAQPLEVVESVYKSLVTDRPRNWDDCVTWARNHWQCQYNNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLEFSTNNDLHMDYILAAANLYALSYGLPSCNDRS-----ALTKLLQDIKVPEFTPKSGVKIHVSDQELQ-SANAS---VDDSRLEELKTLLPSLEASSQ-FKLCPIEFEKDDDTNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELLKIVQGHKKLESYKNGFMNLALPFFAFSEPIAAPKHKYYEIDWT-LWDRFEVKGIQPNGEEMTLRQFLDYFKNEHKLEITMLSQGVSMLYSFFMPAAKLKERLELPMTEIVTKVSKKKLGKHVKALVFELCCNDDTEEDVEVPYVRYTIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B740-1", "uniprot_id": "A0ACD6B740_DANRE", "id": "A0ACD6B740-1", "name": "E1 ubiquitin-activating enzyme", "aln": "----------------------------------------MAQG----DIDEGLYSRQLYVIGHDAMRRMGKADVLIAGMRGLGVEIAKNVILAGVRTVTIQDEGVVEWRDLSSQFYLKEADLGQNRALCSEKQLSSLNAYVKVSASTNKLDENFLSKFQVVVLTSSP-LDEQLRVGAFCHSNNIKFIVADTRGLCGQLFCDFGESFEVIDTNGDPPVSAMISHISKENPGVVNCTDE-ESHEFTDGMFVTFSEVQGMTELNNYGPVEIKVKDSYSFSICDTSNFSDYVKCGVATEVKQPEILSFKPLNVALDEALRDPGLVEMTDYGKTKRHLSLHLAFQALHKFTQKYS-RTPHPRSQADAEVLLTITKELCT----EAKFDK---LDEDAVRNLSLVASGDLAPVNAFIGGLAAQEVVKACSGKFTPLRQWLYFDALECLPQEEGGVLSEDACAPRDSRYDGQIAVFGSDFQNKLKKQKYFLVGAGAIGCELLKNFALIGLGAGEGGSITVTDMDSIERSNLNRQFLFRSQDIGRPKSEAAAEAVKEMNPFMN--IIAQQNRVCAETEEVYTHSFYTGLDGVAAALDNVDAR--------------------------VYLDQCCVRNKKPMLEGGTLGSKGHTMVVVPRLTESYGRSSS---GGQKAIPICTLKNFPHRIEHTLQWARDHFEGLFKQTAQNVNNFLSDPGFVDRTVARGDVEAVEMLEGVYRSLSDDWPENWKDCISWARRQWETLYNNHIRQLLHCFPPDQLTSSGLPFWMGAKRCPHALTFDTNNATHMDFIIAAANLYAQIFGITGSRNRA-----DIQTVLQGVKVPEFTPKSSVKIAVTDQQLN-EENEERKEEDKVKLGMLKEQLSKLQLRDRSFRMHPQDFEKDDDSNFHMDYIVAASNLRAENYDIPTADRHKSKLIAGRIIPAIATTTAAIAGLMCLELYKLVQGHSKITSYRNAYINLATQYFVFSQPCPAPTFTVAGQRYS-LWDDFPVQGCREGQEEMTLEELLKHIEEKHKLKISGLYYGPAVLYSDLS---NHSDRMKLSISDLVRLATKHEVADHQQMLEIIPSFEED-EDCLTVPPIRYLLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22515-1", "uniprot_id": "UBA1_YEAST", "id": "P22515-1", "name": "Ubiquitin-activating enzyme E1 1", "aln": "--------------------------------MSSNNSGLSAAG----EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPD--GTVTMLDD-NRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPE-----FVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGV--DVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDAR--------------------------TYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRD---PPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSG-DVKGVLESISDSLSSK-PHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAAN---GSDEIDQLVSSLPDPSTLAG-FKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKG------DIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9DBK7-1", "uniprot_id": "UBA7_MOUSE", "id": "Q9DBK7-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "-------------------------------------------------MDEELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNLVLTGVGSLTLHDPHPTCWADLAAQCFLSEESLGRNRAEASQAQLAQLNEAVQISVHSGDITEDLLQGFQVVVLTDSK-LEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMTAAIQDISQGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVRHKPLDIALLQPH-----VVAQNTQEVQRAHCLHQAFHVLHKFQQLHG-RLPKPWDPDDAETVVELAQDLEPLKGTEEE----S-LDEALLRTIALSSAGTLSPMAAIMGGVAAQEVLKAISRKFMPLDQWLYFDALECLPEDETLLPSPEDCQPRNCRYDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAAHRLNPDLR--ATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQAR--------------------------HYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWAQDQFEGLFRLSTETINCYQQT--CTS-LSATDRTETLALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFHD------------KVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQSQP-----ALRELLTR--LLESDSRPQNLFS--------AEHGQ------EQLKELQETLDDWRKGPP---LKPVLFVKDDDSNFHVDFVVAATDLRCQNYGILPVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGLRSHGTFRHSYLHLAENHFIRSAPSAPAVQSFRDLKWT-CWDRLKVPAVQP---ERTLKSLLAHLQEEHGLKVEMLLHHQALLYSSGWSSEKQAQHLCLRVTELVQHVTGWKPKPGLKVLVFELSCEGE-EEEMAFPPLHYEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G652-1", "uniprot_id": "A0A8I6G652_RAT", "id": "A0A8I6G652-1", "name": "", "aln": "-------------------------------------------------MDEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDITEDLVRGFQVVVLTDSK-LEDQLNMGALCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDPTEVEPTSAAIQDISQGSPGIVTLRGGSKRPSFYDGDLVMFSDIEGMVELNSHSPQPVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPLDIALLQPC-----MVVQNTQEIQRAHCLHQTFHALHKFQQLHG-RLPKPWDPDDAETVVWLAQDLEPLKGAKEE----S-LDEALLRTIALSSAGSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALECLPEDETLLPSPEDCHPRNCRYDGQIAVFGTGFQEKLSYKHYLLVGAGAIGCEMLKGFALVGLGVRDNGGVTIADMDHVERSNLSRQFLFRPKDTGRPKAEVAAEAAHRLNPDLQ--VTSHTCPLDPTTEDIYDDDFFSRVDGVVAALDSFQARESLTESQVPCPRLWQPHPIPSTLLPGHYVAARCTHYLKPLLEAGTQGTRGSASVFVPYVTEVYKGPTS---AEEAPYPVCTLRHFPSTVEHSLQWAQDEFEGLFRLSAETINDYQQT--CTSSLLGTDGTGILALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFRDNIVELLRKFPSDKVLEDGTLFWSGSKKCPHPLQFDPNQDTHFLYVLAAANLYARMHGLPGSQSQT-----ALRELLTLTLLQEPDSMPQNLFS--------AEFGQ------EQLKELQETLDDWNKGPP---LKPVLFGKDDSSNFHEDFVVAATDLRCQNYGILPVNRARIKQTIGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLGTFRHSYLHLAENHFIRSAPSAPAMQSFHHLEWT-CWHRLTVPAGQP---ERTLESLLAHLQEEHGLTVRMLLHDQALLYSSGWPFEKQAQHLGLRTSS-----AGDRP---------ETQAWAE-SSGV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41226-1", "uniprot_id": "UBA7_HUMAN", "id": "P41226-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "----------------------------------------MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAK-LEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPH-----VVAQSSQEVHHAHCLHQAFCALHKFQHLHG-RPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEP-LDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQ--VIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQAR--------------------------RYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQA--HTS-LADMDEPQTLTLLKPVLGVLRVR-PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWT-----ALRELLKLLPQPDPQQMAPIFASNLELASASAEFGP------EQQKELNKALEVWSVGPP---LKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWT-SWDRLKVPAGQP---ERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGD-DEDTAFPPLHYEL-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** ********:* ** : : **: *::***.*:***::* ** ::*: * . **::* * * .: :.*. :. *:.** * : . : ***** * : *: : .:. :**. : :: ::**** *. * *:*:.: : *.. * :. :. : * :. : * : *: ::*: :**. :.. :: * ... :. * : * ::** .. : .*.* : :. . . : : ** * .** * :. . *:. . ** :: :. : :: :: :: : * :. : *::*.:.****:** : ** *: *::***:*:.**: . ***.*:**** :*: : .: :***:******:** :*::**. * : :.* * :*:***.******. * : *::.** *. :** :. : . ** :: ..*: :: *. ***..:** *: *. **:**.** *: * . *.:* :** * . . : . *:**:: :* :*:: **: *: * .::. . . ::: : * *..: **: ** .:. : ..* * *.::.* .* *. : *: :::*.*.* * .*: . . . .: . . . * * : * * ***.:*.* :::.*.:. *.:** * ..:: : * *:*******:*: :.**: *** *::.. :::.:::** : * .. : *. : : . : .* .:: ::: .. * : * ::**: : ::: :. : . . ", "identical_positions": 231, "similar_positions": 300, "identity": "20.77%" }, { "cls_id": "homologset.agr.SGD:S000001695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES21-1", "uniprot_id": "SAC1_RAT", "id": "Q9ES21-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MAATAYEHLKLHITPEKFYVEACDDGADDVLIIDRVS--TEVTLAVKKDVPPSAVTRPIYGIMGTIHLVAGNYLVVITKKMKVGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSTDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSG------NRASFVQTRGSIPVFWSQRPNLKYKPDPQINKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFAKMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---KVVTNQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLVMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELDS---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP69-1", "uniprot_id": "SAC1_MOUSE", "id": "Q9EP69-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MAAAAYEHLKLHITPEKFYVEACDDGADDVLIIDRVS--TEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLVVITKKMKVGECFNHAVWRATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSG------NRASFVQTRGSIPIFWSQRPNLKYKPHPQISKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---KVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELES---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTJ5-1", "uniprot_id": "SAC1_HUMAN", "id": "Q9NTJ5-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "----MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVS--TEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMS-LLERADQRFVWNGHLLREL----SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNG------SKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---QVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDE-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELES---HSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--VASIGTFFIILYNGKDFVDAPRLVQKEKID-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L244-1", "uniprot_id": "SAC1B_DANRE", "id": "A1L244-1", "name": "Phosphatidylinositol-3-phosphatase SAC1-B", "aln": "-----MASTYNSFNLHTTAEKFYIEACDDGVGDVLAIDRVS--TEKTLTVRKDVPPSAVTRPICGIMGTIRLVAGVYLIVITKKKKVGDLLGHAVWKASDFDIISYKKTVLHLTDNQMQDNKVFLSMLNSVLNTDGFYFATDYDLTHTLQRLSNTSPEFQEMT-LLERADQRFVWNGHLLREF----MAQPELHRFVFPVIHGFIAMRSCCINGKIFDWNLISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIIQYNG------AKASFIQTRGSIPFYWSQRPNLKYKPKPQISKSINHLDGFQRHFDSQIIIYGKQVILNLVNQKGSEKPLEQAFAKMVGSLGNGMIKYIAFDFHKECSRMRWHRLQILVDTVAEL---QDEFGYFLVDSDG---SVQMQQDGTFRSNCMDCLDRTNVVQSLLARRSLQSQLERMAVLHVGQRIEEQAD-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYAVEEADM---NTPLHEPKDWKFLTLPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--SASVVTGGVILFNGRDFVDAPRLVQKEKMD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4VCH0-1", "uniprot_id": "SAC1A_DANRE", "id": "A4VCH0-1", "name": "Phosphatidylinositol-3-phosphatase SAC1-A", "aln": "-----MANAYERFNLHSTPEKFYIEACDDGADDVLVIDRVS--TEMTLAGIKDIPPSGITRPICGVMGTVRLVAGMYLIVITRKRKVGDLFGHTVWKAVEFDVISYKKTILHLTDIQMQDNKTFLTMINNVLNTDGFYFCTDYDLTHTQQRLSNTSPDFQEMS-LLERADQRFMWNGNLLREI----IAQPELHKFAFPVIHGFIVMKPCCINGKVFEWIIISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQFNN------ARASFVQTRGSIPFFWSQRPNLKYKPKPLISKDTNHMDGLRRHFESQVLIYGKQVILNLVNQKGSELPLEQAFAKMVSSMENGFIKYIAFDFHKECSKMRWHRLQILVDAVSDM---QEEFGYFMVSSDG---KVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIEEQAD-FEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDETDS---LTPLHVKKDWKFLLLPVIMVVAFSMCIICLLMAGDTWTETLAYVLFWG--MASALTAAVIVVNGREFVDAPKLVQKEKMD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0I6-1", "uniprot_id": "SAC1_DROME", "id": "Q9W0I6-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "MDSREENAVYDDMNLYIAPQSFIIEP--NGGDELLVIGRHDKVTRVQPASGGLVANLRPTRRICGVLGTIHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIP-----NSFQRKENENYLRLLRQTLDTKFFYFSYRYDLTNSLQRQREVAQSRPEVSGLLQRAEQRFVWNGYVLRQF----NCD-KMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVEFNG------QLTGFVQTRGSMPFHWHQLPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNNVAVNLVDHKGAEGELEATYARLVREMGNPQVRYESFDFHSECRKMRWDRLNILIDRLAHE---QDQFGVYHVFDDG---KLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQRQDSIDLFLGKYLVNDNEGGAVPSPLESKHGWRFFTFPSVLLVAVAMFMITMTYPAEFNTENLLFMLFWG--AMIAVSATGILHYGVEFVQWPRLFPPISFRDP-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32368-1", "uniprot_id": "SAC1_YEAST", "id": "P32368-1", "name": "Phosphatidylinositol-3-phosphatase SAC1", "aln": "--------MTGPIVYVQNADGIFFKLAEGKGTNDAVIHLANQDQGVRVLGAEEFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFN-----SRIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKT-----ADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPN--LVLGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAP-LLTSYQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPHTASIK---SPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLALSTKFMFKNGIQFVNWPKLVDVGFLVVHQTHDKEQQFKGLKYAQSPKFSKPDPLKRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : .: . : * . .. . * .::* ::* * :: . .* . ..:: ..::. . .:: :: ::. *. . ***. ****:: ** :.. : *::**.** : .:: : .:. * *:: *: :*. : :*:*** ***.* : ** *.:*:..** *****: .. .*:*****:*..* : **:*** : : : . **..* :**.: :**:::** * :: : :* : . ::* **** ** .*:*.*:.:*:* : . :::: : . * .: * ...*:**:********:**:**: * :: *: .*. *. : . ::. *****: : *:** *************: * . * ** *** **::** **** ***** : . . :*: : : :* :: .*.:: : . : *.. : * * : :. * :**: *:*. : ", "identical_positions": 153, "similar_positions": 177, "identity": "23.65%" }, { "cls_id": "homologset.agr.SGD:S000001696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54319-1", "uniprot_id": "PLAP_RAT", "id": "P54319-1", "name": "Phospholipase A-2-activating protein", "aln": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPG---AFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTIKLWKA-GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLGVYYGHTNYIYSISVFPNCRD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTEADERTASAEEIKAFERELSQATIDSKT-GDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE-RVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTS-FSDPFTGGGRYVPGTSGP-SNTVQTADPFTGAGRYMPGSAGMDTTMAGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGSAPEEKKLTEDDLVLLEKILSLICGNASEKP--TAQQLQVLWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHN----IEGKAQCLS-VISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEP------AKVSECCRLILNLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27612-1", "uniprot_id": "PLAP_MOUSE", "id": "P27612-1", "name": "Phospholipase A-2-activating protein", "aln": "MASGASRYRLSCSLPGHELDVRGLVCCLYPPG---AFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTIKLWKA-GRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLEVYFGHTNYIYSISVFPNSKD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQATIDSKT-GDLGDINAEQLPGREHLSEPGTREGQTRLIRDGE-RVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTS-FSDPFTGGGRYVPGTSGP-SNTVQTADPFTGAGRYMPGSAGMDTTMTGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGTAPEEKKLTEDDLVLLEKILSLICNNSSEKP--TAQQLQILWKAINWPEDIVFPALDILRLSIKHPNVNENFCNEK-GDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHN----IEGKAQCLS-VISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYVSVSEP------AKVSECCRLVLHLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y263-1", "uniprot_id": "PLAP_HUMAN", "id": "Q9Y263-1", "name": "Phospholipase A-2-activating protein", "aln": "MTSGATRYRLSCSLRGHELDVRGLVCCAYPPG---AFVSVSRDRTTRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTVKLWKA-GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCRD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKT-GDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE-KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPS-FSDPFTGGGRYVPGSSGS-SNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEAVTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKP--TVQQLQILWKAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLALRTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHN----IEGKAQCLS-LISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSEP------AKVSECCRFILNLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPY2-1", "uniprot_id": "Q9VPY2_DROME", "id": "Q9VPY2-1", "name": "", "aln": "MEPSLDNYKLSCELLGHSMDVRAVAVGPPTPEGRQTILSGSRDKSTKVWKPHG--NEYLESLTLQDHKNFISYICFLES-----ERWICTASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFVALEGHEAAVWAVATLKE-QRKYVTGGADRNIYYWNAKGEKLRLLKGHTDCVRGVMGLDANTLLSCGNDAVLRFWNE-DGECVREMNGHSNYIYSMARNEALGDQVVVSCGEDSTLRMWNVITGDELGAPIIHPGISVWSVTCLQNGDIVTGCSDGVVRVFSHVPARQASEAVLKAFD--LVVATRKSQINEEIGGVKKTDLPGPEALLSNGTREGQTKMVRHADGSVKCYTWTLGN--WNLVGDVTGATGGTQSNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDDPWQAAQTFIHRHSLPQAYLDQVANFIIKNSEGPVLMEQAPTGYQDPFTGGSRYVPGSSNTNMGSGGNVDPFTGASSYSTASS------------NAQSQVDVNFVRSGDKHFPVSNYRIFDTCDAKKVLEKMIEFNG------KLSLPDGRVGEEVLLAVIKLADQSPELDLTSLEALAILLKWPASMQFPVLDILRLAVRNEAIFSVLNNSH---NFLATVIPQLS--GSAPNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGS-ANLQIAVATFYLNLTISQTLDVA----KSEVCHVVTSGIVELLKWAKDLEACYRSMQAIGNLTTTSCGQETIAQVVSVDYVMDKLRELTITPQDKNFSKVNSVGQALLAVF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36037-1", "uniprot_id": "DOA1_YEAST", "id": "P36037-1", "name": "Protein DOA1", "aln": "-----MGYQLSATLKGHDQDVRDVVAVDDSKV-----ASVSRDGTVRLWSKDD---QWLGTVVYTGQG-FLNSVCYDSEKELLLFGGKDTMIN--GVPLFATSGEDPLYTLIGHQGNVCSLSFQD--GVVISGSWDKTAKVWKE----GSLVYNLQAHNASVWDAKVVSFSENKFLTASADKTIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLP-NGD--IVSCGEDRTVRIWSK-ENGSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKT----IEFDESKLSPYEILQSPGRKEGQIVVVKSPQGTIEAHQFSNSS--WKKVGDVVG--AGATGNDKKIEFEGKTYDYVFDVDIEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDN------------------------------------------------------ASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINS-----------NEKTFDDEILAQIGGALHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNITLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAK---QSQNLAIAVSTLIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEPTLRQFANSVTWLANIKRSYGNVPR--------FKDIFDDLS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**. * **. *** :. . * *** :.::* .. : .: *:. :* . * * : :: .. ** * **:..**:** ::*****.**:** . . *:.* *:** . : : :*..**:.: *: * * ** : :. ::**.**. :: : *: : ** .::*.: * .*: .** ::*:* .. * *. *:*. :.****:.*.**.::*:*:. * ** :: :. : :* .*: .. .*. * * . * :*** ::: : ::.: :: .. * :***.* .. .. * .*** :*:**.:*:.: *. *** * **:*: .* .*: : .* : ***.:**:.*::* * . ..* : :* .: :: :. :: : ::*. : :. : : .. * : :. .: *. **:** ::: . : : : : * : . : : : ::. :. . . *: **::*: :* : . .. :. : : : ** :* * *.* : . :*: : :.: ... : ", "identical_positions": 142, "similar_positions": 220, "identity": "17.15%" }, { "cls_id": "homologset.agr.SGD:S000001698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97608-1", "uniprot_id": "OPLA_RAT", "id": "P97608-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEEGVLLPRGRPLDTSRIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVLEVDERVVLYRG-------EPGAGSP---VKGRTGDLLEIQQPVDLEALRGKLEGLLSRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSATTYHLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLTNGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQVQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATACS----PRAGDFGAAFVERYMREFGFIIPERPVVVDDVRVRGTGRSGLQLEDTPKIQTGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVTDTGDIRISVGAEGPSMAD-----TRLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAEDHMDDGSPICLRVQINLSQGSAVFDFTGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVRVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACSASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGARGLNLLIRK-DGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPLFPAFPERGSVFEYRRAQEAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K010-1", "uniprot_id": "OPLA_MOUSE", "id": "Q8K010-1", "name": "5-oxoprolinase", "aln": "MGSPEERFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRG-------EPGAGSP---VKGCTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCS----PRAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTGRSGLQLEETSKIQSGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRISVGAEAPSMID-----TKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQSRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQ-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRK-DGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPEDP--APPPGSPPLYPAFPERGSVYEYRRAQEAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14841-1", "uniprot_id": "OPLA_HUMAN", "id": "O14841-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEAGMLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTRGFRDLLHIGTQARGDLFDLAVPMPEVLYEEVLEVDERVVLHRG-------EAGTGTP---VKGRTGDLLEVQQPVDLGALRGKLEGLLSRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSLSSEAMPMVRIVPRGHTACADAYLTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAPMDTFSGSSAVLSGPAGGVVGYSATTYQQEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGENQPLSPEASRKALEAVATEVNSFLTNGPCP-------ASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLLY-APETFVQLDQRLSRLEEQCVDALQAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATARS----PRAGDFGAAFVERYMREFGFVIPERPVVVDDVRVRGTGRSGLRLEDAPKAQTGP----------PRVDKMTQCYFEGGYQETPVYLLAELGYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICISVGAEVPGTVG-----PQLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKVPNCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEVFGNLNAPRAVTLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------AHMGYYETVAGGAGAGP------SWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRR-GSGGRGRFRGGDGVTRELLFREEALLSVLTERRAFRPYGLHGGEPGARGLNLLIRK-NGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPQALAFPEHGSVYEYRRAQEAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Z6-1", "uniprot_id": "E7F6Z6_DANRE", "id": "E7F6Z6-1", "name": "", "aln": "MAETKGKFDFAIDRGGTFTDVFARLPDGRE---KVLKLLSHDPQNYKDAPTEGIRRVLEEETGKSFPRDQPVDTSQIGWIRMGTTVATNALLERQGERTALLVTSGFKDLLHIGTQARPNLFDLEVCMPDVLYEEVIEVEERVILRQDSC-----QLPRNEPKRIVTGSTGESLEVWRELDLQRVEQDLRRVQSKGIRSLAVLLLHSYTWAAHEKAVGSLAKRLGFAQVSLSSEVMPMVRAVPRGYTVCADAYLTPKIHLYLTKFTAGFKGGLKGVDVLFMQSDGGLTPMEQFCGSRAVLSGPAGGVVGYAVTCYKSTEKKPVIGFDMGGTSTDVSRY-AGQYEHVFEATIAGITLQAPQLDINTVAAGGGSRLFFRSGMFVVGPESAGAHPGPACYRKGGPLTVTDANLALGRLLPSFFPKIFGPGENEPLSTEETMKHFSKLTQEINHFLSTNQTSNSASGAQLSKMSIEDIAMGFINVANEAMCRPIRALTQAKGHDTSEHVLACFGGAGGQHACAIARALGMKMVFIHKYSGVLSAYGLALADVVEEVQEPCSLQY-EAGSFSELDRRIEQLSQRCDEILRKRGFSRSQINIEVFLHLRYEGTDCALMITATDHPSNASS----CRTGDFRTAFTKRYLKEFGFTITDRPIMVDDIRVRGSGKSGIRSEVQAKAGQKS----------PNPIKMTQCYFEDRYLDTSVYLWEDLSCDHSIQGPAIIIDKNSTILVEPTCVAHLTEDGDVCIAVGMGTQCVLG-----TELNTIQLSIFSHRFMSIAEQMGRVLQRTAISTNIKERLDFSCAVFGPDGGLVSNAPHIPVHLGAMQETVQFQIKAAGGSLKEGDVILSNHPCAGGSHLPDLTVITPVFRDGVSAPVFFVASRGHHADIGGITPGSMPPHSTSLQQEGAVFTSFKLVTGGIFQEKAVTEALM-APAQYPGCSGTRNLRDNLSDLRAQVAANQRGCQLVGELITSYGLDVVQAYMGHIQSNAELAVRDMLKDFAHRQREKTGSLEVEAEDQMDDGTLIRLKVQINEEQGSAVFDFTGTGTEVWGNCNAPRAITLSALIYCLRCMVGQDIPLNQGCLAPVKVIIPPGSILQPSQNAAVVGGNVLTSQRVVDVIFKAFQVCAASQGCMNNVSFGC------------EKSGYYETVAGGAGAGP------SWNGRGGIHTHMTNTRITDPEILESRYPVILEQFSLRP-DSGGAGLYRGGDGVIRKLRFRSPVVLSVLTERRSTKPYGLHGGKNGAPGLNLLHKT-DGRVLNLGAKTTISLDPGDMFSLFTPGGGGYGRMDEL--DGDHHLPSKRRCLHE---------SQNKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W247-1", "uniprot_id": "Q9W247_DROME", "id": "Q9W247-1", "name": "5-oxoprolinase", "aln": "MSGT--KYCFAIDRGGTFTDVLCICPNGKV---RTMKLLSEDPERYSDAPREGIRRILKEETGEDLAASGLVDTSKIGWVRMGTTVATNALLERKGDPVVLVVNSGFRDLLYIGNQARPKIFDLNIRKPANLYKSVVEVDCRIVPKQAD------RCELNHSWKELEGVAGTKYLEVRPVDEVAVRQALSDARDQGVSSVSVVLAHSYACPEHELRVGAIARELGFSHVTLSHQAMPMCRVVARGYTACAEAYLTPHVDRYLASFKSGFDKQLEGVDVLFMQSDGGLTNMENFRGARAILSGPAGGVVGYALTGAR-ETELPLIGFDMGGTSTDVSRY-AGTYEHVIESTTAGVTIQAPQLDINTVAAGGGSRLFFRSGIFVVGPESAGSHPGPACYKKGGPLTVTDANLILGRILPQYFPKIFGPQENEPLDHEIARSKFVELQAEINNYLKSSGDN--------RVLSVEDVALGFIRVANETMCRPIRALTQSRGLDTANHVLSCFGGAGGQHACSIARNLGIAKVVVHKYAGILSAYGMALADVVQEFQEPNGLEF-SDANAQQLKERLDALSKQCQDKLSEQGFKR--IELEPFLHLRYEGTDGALMVAPSTGKQSSDSNPLLAAYGDFHATFLERYRTEFGFVLQNRRIIVDDIRIRGLGKNETPPESKVQAAAEAK---------PPAEANTRLYFDQGAFDSPIYLTKNLLAGHRITGPAVLIDQLSTIVVEPECGIQVTQFGDLIMDVKTGGKHGIN-----ADLDPVHLSIFSHRFMSIAEQMGRVLQRTSISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQYQLRVRGETLKNGDVILANHPSAGGSHLPDLTVITPVFYETHPRPVFFVASRGHHADIGGITPGSMPPHSTSLAQEGAAFKSFLIVENGLFQEQQIIEQLT-TPTAAKGAVGTRNLSDNLSDLKAQIAANHKGIQLVAELIGSYGLDVVQAYMSHIQKNAELAVRDMLRQIGRDTLERTGSTVLEAKEFMDDGSPIALKVTIDAEQGSALCDFTGSGVEVWGNCNAPRAITLSALIYCLRCMVGHDVPLNQGCLAPIQVIIPKNSILDPSEGAAVVGGNVQTSQRIVDTVLKAFGVCAASQGCMNNITIGD------------ESWGYYETVAGGAGAGP------GWHGAGGVHTHMTNTRITDPEILELRYPMILKRFCLRTDGSGGRGQFHGGEGVERDLLFRKPVTLSVLTERRTLQPYGLAGGESGKSGRNLVVKR-DGRVIALAGKTCIDVEAGDTFAMKTPGGGGYGPIEDFSKSGESLNQETSKRYVERGTVFNYLQCQESA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28273-1", "uniprot_id": "OPLA_YEAST", "id": "P28273-1", "name": "5-oxoprolinase", "aln": "--MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNYPDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITTKGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQEGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNIAREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLS-HAEDTHIQFMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSRYGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPAAYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN-------------SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSLGIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIKNLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQ-----------WNFREWFSEAHKKEFGFSFDDKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVDTAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILN-SHIFIKINQKAAKTLSKSGYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVANAPHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG-ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFVEDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTNASESIKKMLAKM----VEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVYGNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGNVLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSGAGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRR-GSGGKGKYTGGNGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNTIYAQPGDRFIIKTPGGGGFGQYKD--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***:****** . *: .:**** ** .* *** *****:*: :. . :* *.: :*****:***. ***:*: .::.. **:* * ** *:* .:*:* : **. *:*:: *: . . : * :* : * :. * *: *::: : ***: . ** ** :*:.:**::*:** :. ** : :.*.:: *:***** :. *: : *:. :...: **:*****. * * ::********:**: * *:*************** * ***:*: **: :*:*****:******.* * ::.*:* ***:**.:.****.*:****:*:***** ***::* ** **** *::.*. * : : : :* * :::*::* **:.**** *.**:**:*:::* : * * .********* ::* **: * :*:::.:*** *: ****:.* *** .: . ::..*: *.:.. . * :.* * * * :*:***:**: :**: :* * : : **** : :: :::**:*:*. *:. * . : **: ::.:: :* . : **.:: * .* :: * . : . ..: : : . ::.: *********.** *** *::*::***:*********:*...*.**:****:*****:*. :. * : *: ***:::*** **:****:***** * :*:****.******** ***:**:*. * :**:.: * :* *:***: : : : * .. *:*.: **:***:**:*** :* **:..* .*.* .: **. ** **. :::.** : : . ...:: :***: * *:* * .: . : :* *:. :*:** ***.*:* **::*****:**.*:******* *: : ** .*:*.* ******** ****:.*.:: :* . : *** **.::* *****:.**:***. .*:* ..:*::*****:**.*::* ***::*..* :* .*** * : **:** *.: **. . *:*:*** *:*: **: * * ** : * : :..*. : .** * : ******:* .: ", "identical_positions": 498, "similar_positions": 355, "identity": "36.83%" }, { "cls_id": "homologset.agr.SGD:S000001699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63707-1", "uniprot_id": "PYRD_RAT", "id": "Q63707-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRQLR---------KRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFD-KNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELR-HLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELG--IDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35435-1", "uniprot_id": "PYRD_MOUSE", "id": "O35435-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRQLR---------KRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVRVISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFD-KHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGINLGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELR-RLLSKVLQERDALKGPQKPAVLVKIAPDLTAQDKEDIASVARELG--IDGLIITNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02127-1", "uniprot_id": "PYRD_HUMAN", "id": "Q02127-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRHLK---------KRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFD-KHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELR-RLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELG--IDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32748-1", "uniprot_id": "PYRD_DROME", "id": "P32748-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MDQDHLKNAKNATRRVGRLRSLGIVTVGGAALVAGITAYKNQDQLFRTFVMPAVR-LLPAEASHQLAVLACKYRLCPVSQYHDDQNLHTSFFGRMLSNPIGIAAGFD-KNAEAVDGLQDLGFGFIEVGTVTPAAQEGNPKPRVFRLTEDKAIINRYGFNSDGHQAVLQRLRLLRKKE---NFNGV-VGVNLGRNKTTMSPIADYVQGVRVFGPVADYLVINVSSPNTKGLRDMQSKEKLR-ELLEQVNDTKSSLDKNKNVPILLKLSPDLSLDDMKDIVWVIKRKKSRVDGLIVSNTTVSRENIEKNKLAEETGGLSGPPLKARSTEMIAQMYQLTDGKIPIIGVGGVASGYDAYEKIEAGASYVQIYTALVYEGPALVEDIKAELSALITRLGHTNVADVVGTNSKFYLPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28272-1", "uniprot_id": "PYRD_YEAST", "id": "P28272-1", "name": "Dihydroorotate dehydrogenase (fumarate)", "aln": "----------------------------------------------------------------------------------MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLEREGNPEPRYISVP--LGSINSMGLPNEGIDYYLSYVLNRQKNYP------DAPAIFFSVAGMSIDENLNLLRKIQDS-EFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKP---KNGFGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.. **. *:*.. : :* * . * . :.*. :****.** : :. . ** *: ..* . : ::: .: :. : . : . :: . . :*:*.**. * .: . .* . * :* . : . : *: . ::: . . :.. :. :. . . **:.* :: : : :* : :**.**: ** ** *:: .*** :*: * * * :. :: **. :: *. : : * ", "identical_positions": 52, "similar_positions": 98, "identity": "12.62%" }, { "cls_id": "homologset.agr.SGD:S000001701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76EQ0-1", "uniprot_id": "SRR_RAT", "id": "Q76EQ0-1", "name": "Serine racemase", "aln": "----------------------------------------------------MCAQYCISFADVEKAHLNIQDS---VHLTPVL--TSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTS-LSWVKQ---------------AERPAP--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZX7-1", "uniprot_id": "SRR_MOUSE", "id": "Q9QZX7-1", "name": "Serine racemase", "aln": "----------------------------------------------------MCAQYCISFADVEKAHINIQDS---IHLTPVL--TSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKAL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQTVSPEVKNVCIVLSGGNVDLTS-LNWVGQ---------------AERPAPYQTVSV--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZT4-1", "uniprot_id": "SRR_HUMAN", "id": "Q9GZT4-1", "name": "Serine racemase", "aln": "----------------------------------------------------MCAQYCISFADVEKAHINIRDS---IHLTPVL--TSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKAL-KPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSS-IGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWVKQ---------------AERPASYQSVSV--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36007-1", "uniprot_id": "LTHAD_YEAST", "id": "P36007-1", "name": "L-threo-3-hydroxyaspartate ammonia-lyase", "aln": "-------------------------------------------------------MIVPTYGDVLDASNRIKEY---VNKTPVL--TSRMLNDRLGAQIYFKGENFQRVGAFKFRGAMNAVSKLSD---EKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPEDAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTSAKELLEEVGQLDALFVPLGGGGLLSGSALAARSL-SPGCKIFGVEPEAGNDGQQSFRSGSIVH-INTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVVEPTACLGFAGALLKKEELVG---KKVGIILSGGNVDMKRYATLISG---------------KEDGPTI-------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VHF0-1", "uniprot_id": "Q9VHF0_DROME", "id": "Q9VHF0-1", "name": "L-serine deaminase", "aln": "MSQAVKTETPKEPNVVAAKANGGTAVNGKLEAQKRPRHVSGGVEEIIDPFCNPEKPQRISFHDVTSAAFLIRGG---VERTPCP--KSTSS-DLYGMELYLKKDFLQYTGSFKERGARYALLSLTE---EQKRTGVISASLGNHAQALCYHGWKLNIPVTVVMPKAAPIMKIQKCRNYKARVIVDGNDMGEAKSLAMRMSREEGLLYVNGYDHPHIMAGQGTIGLEILEQVPEPDAVVVPVGGGGLIAGIATAVKAL-SPKTKIIGVESEKCASFTRAMENDGPIH-TPIKNTLADGLAVPKVGYNAYATAMPLIDRMVVVKEEWIAVAILRLVEEEKCVVEGAGGAGLAAILAGHLDELKG--KKVVVLLCGGNIDTTVFGRCLERGLAAVGRLVKFNVEVSDRPGGINDLCALLVRVGVSIKDIMHERAWLRDVYTVEVKVVCETVDWTHSLQLKNELKKFYSKVQFSDVPLALSNDTDS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ACD6B6W2-1", "uniprot_id": "A0ACD6B6W2_DANRE", "id": "A0ACD6B6W2-1", "name": "L-serine ammonia-lyase", "aln": "--------------------------------------------------MGDVSADMITVEMLREACETVRCSPMDVIKTPMIPWSQTTLPLHTSCNIHIKLENMQRTGSFKIRGVANQFAKRHKG------DHFVTMSAGNYGKAFSYACKHYGSKGKVVMPETAPISRSVLIQNLGVEVERVP--TTQLMGVVNRCVQEDGMTFLHSIDDPDLIAGHSSLGFEILDVLPYPDVVVVCCGGGGLLSGVAAAIKLSGCEDTKIYGVEPEGACTMYKSFIEKRPVG--MDAKSIASGLAPPFAGTLAYQLCQRYVEKIVLVSDEEIKSAVSTLYKAG-LVVEPSGTAAFTAIINDKIPDIQD--KNVVVILSGGNIGKDELNNFPD------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* :: : ** .. . ::.:* : :* .*:** **. . .:: * **:.:*: . :*:*: ** : . : . : : * : :.* ::**:.: . *:*: : *.:.* ****:::* * : : *: ..*.. :: . :::*.* * :: :: :. *.:: : . : ::* :. ..:. : : : *:: ::*.***:. ", "identical_positions": 44, "similar_positions": 98, "identity": "9.13%" }, { "cls_id": "homologset.agr.SGD:S000001704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AT66-1", "uniprot_id": "MOT7_MOUSE", "id": "B1AT66-1", "name": "Monocarboxylate transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNS-----KISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLG---YCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPG-------------------------------------------------------------------------------------------------------------------------------------------------------QSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLV-------------------------------------------------------------------------TAPKHSQMKAPLLDFSVLKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAF-LLSTMAIAEVFGRIGAG-FVLNREPIRKIY----IELICVILLTASLFAFTFATEFWG-------LMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKG------------------------------------LCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15403-1", "uniprot_id": "MOT7_HUMAN", "id": "O15403-1", "name": "Monocarboxylate transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNS-----RISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLG---YCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGP--------------------------------------------------------------------------------------------------------------------------------------------------------ASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVK------------------------------------------------------------------------TSPRPSEKKAPLLDFSILKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAF-LLSTMAIAEVFGRIGAG-FVLNREPIRKIY----IELICVILLTVSLFAFTFATEFWG-------LMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMG------------------------------------LCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFG6-1", "uniprot_id": "A0A8M9PFG6_DANRE", "id": "A0A8M9PFG6-1", "name": "Monocarboxylate transporter 13", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKR----GTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTAT-----ASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFG---YALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSRHDYFKDSIE--ENEHELSKCSNNRADSDPMKVKVIR-------------------------------------------------------------------------------------------YVDYTLIAN-SRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVEEYQAAS-LMSISAVLDLLGRVFFG-WVANLRLVETVH----QLIGTVVLLGAVLLLCPLATTFTQ-------LAVFSAGYGLVFGATVAIHITVLAE--VVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNK--------------------------------------------KETEHKKDICSENEEEHEDLKNRNFVFGKS-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70451-1", "uniprot_id": "MOT2_MOUSE", "id": "O70451-1", "name": "Monocarboxylate transporter 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEP-----SAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------NTKKSKS------KVGSRHD--STLKKASKVSTAQKVNR-------------------------------------------------------------------------------------------FLDFSLFMH-RGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAF-LLSVMAFIDMFARPSVG-LIANTSLIRPRI--QYLFSSAIIFTGICHLLCPLATTYSA-------LVVYVVFFGLGFGSISSLLFECLMD--IVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINY----------RLLDKE-----------------RKREKAKKKKSASHASREMEALNRSKQ-DEVTVKASNAHNPP-SDRDKESNI------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63344-1", "uniprot_id": "MOT2_RAT", "id": "Q63344-1", "name": "Monocarboxylate transporter 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAAKSKS------KVGSRQD--SSTKRLSKVSTAEKINR-------------------------------------------------------------------------------------------FLDFGLFTH-RGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAF-LLSVMAFTDMFARPSVG-LIANTSLIRPRI--QYLFSVAIMFTGICHLLCPLAHSYTA-------LVVYVIFFGIGFGSISSLLFECLMD--QVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINY----------RLLEKE-----------------RKREKARRKKSASQASKEMEALSRSKQ-DDVTVKVSNTHNPP-SDRDKESSI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60669-1", "uniprot_id": "MOT2_HUMAN", "id": "O60669-1", "name": "Monocarboxylate transporter 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPMP-----SAPPVHP-PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYS-----EIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLG---LAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTSKSKN------KTGKTEDDSSPKKIKTKKSTWEKVNK-------------------------------------------------------------------------------------------YLDFSLFKH-RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVG-LIANSKYIRPRI--QYFFSFAIMFNGVCHLLCPLAQDYTS-------LVLYAVFFGLGFGSVSSVLFETLMD--LVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINY----------RLLAKE-----------------RKEENARQK------TRESEPLSKSKHSEDVNVKVSNAQSVT-SER--ETNI------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53986-1", "uniprot_id": "MOT1_MOUSE", "id": "P53986-1", "name": "Monocarboxylate transporter 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG------GPVGYTPPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQV----------------------------------------------------------------------------------------------------------------------------------------------------------------------KLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINK-------------------------------------------------------------------------------------------FLDLSLFTH-RGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAF-LLSILAFVDMVARPSMG-LAANTKWIRPRI--QYFFAASVVANGVCHLLAPLSTTYVG-------FCVYAGVFGFAFGWLSSVLFETLMD--LIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINY----------RLLAKE-----------------QKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQ--QHSSG-DPTEEESPV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53987-1", "uniprot_id": "MOT1_RAT", "id": "P53987-1", "name": "Monocarboxylate transporter 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG------GPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQG----------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNK-------------------------------------------------------------------------------------------FLDLSLFTH-RGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAF-LLSILAFVDMVARPSMG-LAANTRWIRPRV--QYFFAASVVANGVCHLLAPLSTTYVG-------FCIYAGVFGFAFGWLSSVLFETLMD--LVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINY----------RLVAKE-----------------QKAEEK-KRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSG-DPAEEESPV------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVV---DEGP-TGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGGGTEPRGPQRPPQR-------------------------------------------------------------------------------------------LLDLSVFRD-RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAF-LLTILGFIDIFARPTAG-FITGLKKVRPYS--VYLFSFAMFFNGFTDLTGSTATDYGG-------LVVFCIFFGISYGMVGALQFEVLMA--IVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCI--------GKRKRPEV-----------------TEPEEVASEE-KLHKPPVDVGVDSREVEHFLK---AEPEKNGEVVHTPETSV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35910-1", "uniprot_id": "MOT4_RAT", "id": "O35910-1", "name": "Monocarboxylate transporter 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVV---DEGP-TGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASGGAEPHGPQRPSPR-------------------------------------------------------------------------------------------LLDLSVFRD-RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAF-LLTILGFIDIFARPTAG-FITGLKKVRPYS--VYLFSFAMFFNGFTDLTGSTASDYGG-------LVVFCIFFGISYGMVGALQFEVLMA--IVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCI--------GKRKRPEV-----------------TKPEEVASEEEKLHKPPVDVRVDSREVEHFLK---AEPEKNGEVVHTPETSV------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGAGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRRDPSPHGGPARRRR-------------------------------------------------------------------------------------------LLDVAVCTD-RAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAF-LLSIVGFVDIVARPACG-ALAGLGRLRPHV--PYLFSLALLANGLTDLISARARSYGT-------LVAFCIAFGLSYGMVGALQFEVLMA--TVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGA-----------------SDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E8K6-1", "uniprot_id": "MOT6_MOUSE", "id": "G5E8K6-1", "name": "Monocarboxylate transporter 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNS-----ETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLG---MCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPVATNEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------PEPKEDPLLPPKIPT-------------RSCLATCVSTIRY-------------------------------------------------------------------------------------------HLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAM-LMSIVGFCNIFLRPMAGLLLAGRKSLAAYR--KYLFAVAILINGLTNLICTVSADFRV-------LLGYCLVYSLSMCGVGILVFQVLMD--IVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSGSLILGVGFYAAE----------KKKLKQ-----------------DGQAKMEN----ATSEMTP--------MHDLTSEDKDSAKKQPYPESIYMTNV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15375-1", "uniprot_id": "MOT6_HUMAN", "id": "O15375-1", "name": "Monocarboxylate transporter 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNS-----ETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLG---MCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVA----------------------------------------------------------------------------------------------------------------------------------------------------------------------PETKECPPPPPETPA-------------LGCLAACGRTIQR-------------------------------------------------------------------------------------------HLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LISIIGFSNIFLRPLAG-LMAGRPAFASHR--KYLFSLALLLNGLTNLVCAASGDFWV-------LVGYCLAYSVSMSGIGALIFQVLMD--IVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ----------KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAK1-1", "uniprot_id": "A0A8M9QAK1_DANRE", "id": "A0A8M9QAK1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEGVEVHQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNT-----ETSWVPAIMMAVLHACGPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMG---FSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKPK----------------------------------------------------------------------------------------------------------------------------------------------------------------------METRTKETDNHHLKTNCLSVHQGLKGRLRATLSTIMTFLRR-------------------------------------------------------------------------------------------HMAFDLLCSNPYFCAYALGVSWMMLGFVVPLVYLVPYATAYGMEQDQAAL-LMAILGLINIIVRPATA-LVFGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLV-------LLVYVILFGFSMSLVGSLLFTVLMD--TVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLSFYWLD----------RRRDRE-------------------QVKSSS------AHQDP---------HSLKPSLKMTIDCEYSPVPLHSKNTRDTETDV----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CE94-1", "uniprot_id": "MOT13_MOUSE", "id": "Q8CE94-1", "name": "Monocarboxylate transporter 13", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVR------------RAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA-----RVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSG---WALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAVGGPGAQIT--------------------------------------------------------------------------------------------------SLLRH-GPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAF-LLSVAAVSDLVGRVASG-WLGDAVPGPVAR----LLMLWTTLTGVSLALFPVAQASST-------LVVLAVAYGFTSGALTPVAFSVLPE--LVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCIS-------VSTSRP--------------------------QDLVIEASDT-----------KIPLPKEEG---LGEN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1QL69-1", "uniprot_id": "A0A8M1QL69_DANRE", "id": "A0A8M1QL69-1", "name": "Monocarboxylate transporter 13", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKPQKTEEEQRPCPQGAAPDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQ-----AVSWITSIGLAMQQLMSPIGAAASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLG---WALVFTPTMASVMQYFTKRRSLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIRPLGTPKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVKTENSTKLNKCSFLLSRIY-----------------------------------------------------------------------------------ECFELSLLTH-RGFVTYAVAITFFNAGYFIPYVHLVAHSRHIGFTEYQAAF-VISITGVADIVGRVASG-WASDLGKIRLLH----MLVVWTGLLGLSLMLIPVAVVYAG-------LLLVSIVYGFCAGAMAPLAFAVVPE--IVGIERVLGALGLLQLIESAGGLLGAPLSGWLKDSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTA-------PPAPSPS---------------KKKSQEGSAEDGLIGESTSSNAINETLCSGDHIPYSDEEVKVCLSNDATHSVQEQEEIPQEMTHRSNFA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5NC32-1", "uniprot_id": "MOT11_MOUSE", "id": "Q5NC32-1", "name": "Monocarboxylate transporter 11", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTP-----------KPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ-----DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLAPPRTPLAALG-----------------------------------------------------------------------------------------------LGLFKR-RAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAAL-VVAVAAVGDACARLASG-WLADQGWVPLPR----LLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPG--LVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCR-------PASPPA------------------------------TPPPER---------GELLPVPQVSL---LSAGGTGSIRDTTC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCK7-1", "uniprot_id": "MOT11_HUMAN", "id": "Q8NCK7-1", "name": "Monocarboxylate transporter 11", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTP-----------QPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQ-----DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAPPRSPLAALG-----------------------------------------------------------------------------------------------LSLFTR-RAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGARLVCG-WLADQGWVPLPR----LLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG--LVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCG-------PASPPA------------------------------TPPPET---------GELLPAPQAVL---LSPGGPGSTLDTTC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGC3-1", "uniprot_id": "MOT12_MOUSE", "id": "Q8BGC3-1", "name": "Monocarboxylate transporter 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYS-----QTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSVPE--KNHNRESQREDCKQASPYSPLTKECTETRL----------------------------------------------------------------------------------------CCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAF-LMSILGVIDIVGNITFG-WLTDRRCLKNYR--YVCYLFAVALDGLCYLCLPMLQTFPL-------LVPFSCTFGYFDGAYVTLIPVVTAE--IVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKR-----------------------------------TQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSM3-1", "uniprot_id": "MOT12_HUMAN", "id": "Q6ZSM3-1", "name": "Monocarboxylate transporter 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYA-----QTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------HTTPE--QNHVCRTQKEDIKRVSPYSSLTKEWAQTCL----------------------------------------------------------------------------------------CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF-LMSILGVIDIIGNITFG-WLTDRRCLKNYQ--YVCYLFAVGMDGLCYLCLPMLQSLPL-------LVPFSCTFGYFDGAYVTLIPVVTTE--IVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRK-----------------------------------TQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503M4-1", "uniprot_id": "MT12B_DANRE", "id": "Q503M4-1", "name": "Monocarboxylate transporter 12-B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQEKKKGGVLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYS-----GTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLG---FALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPIILKEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------EACPLPVDSECGYSVKPPTLNGGPTRSAASDAKQR------------------------------------------------------------------------------------------CFQSMQEYHFLLMPDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAF-LMSILGVIDIVGNITFG-WLTDRRCLKKYR--NICYMFAVGMEGLCCLFIPLLRTFVW-------LVPFSVLYGYFDGAYVALIPVVTSD--VVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQR-----------------------------------NQKKNSLS-KIPKLVSCEGKQVDYYPPKNKDLMLIIPATS-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R0M8-1", "uniprot_id": "MOT5_MOUSE", "id": "Q8R0M8-1", "name": "Probable monocarboxylate transporter 5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKKEKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLRFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLG---SAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLT-FLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIHSQS-----------------------------------------------------------------------------------------------------------------------------------------------------------NNNSDIENKG-----SILSATEPEAS--YKTETSKCKETQEPFIKDSTMKKSEQPTTTLT------V---------------------------------------LGNQSEEFSNRPHRNRPLLMSNGKSHKKKFVSWNCKQKLLDISLFRN-PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASY-LVSVAGITETVSQLISG-WIADQNWIKKYQ----YHKSYLILCGVTNLLAPLATTFPL-------LMAYTILFAIFAGGYLALILPVLVD--LSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKR--------------------------------------------------------KQSDLLRTTIK---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QW16-1", "uniprot_id": "F1QW16_DANRE", "id": "F1QW16-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPKEQHSDGKTAKTPCSELKAKVMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSE-----SISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLG---FALLYQATSVVIVTYFRKRLATAYSIGRSGMGLT-FALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHPA-------------------------------------------------------------------------------------------------------------------------------------------------------SPISNSTIHKTEKDPLKNNMNGNTPVANGTSKSDSSPPIHKDTLIIKNPVHEQNSLPHLDLKKPTQNGV---------------------------------------NGTDSSQTKTSPEMNGVSPVDSLLENGRTENVPENSPKVLDFSLLKN-PFFCIYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDASF-IISVAGITETVAQLASG-WVTDRNLVHKYH----YHKAYLILCGVVNLLSPLATSYIL-------LMVYAVFFAIFCGGYMALLLPVLVD--LVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISLFLEPLARRWQA--------------------------------------------------------RKERLETLNQELMWSNGCFCPAPQRNGVV---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP-----------------------TPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKG-----YTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLG---FGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASY-LISTIGVANTVGRIILG-YISDKPWVNRLL----VYNVCLTACGVSTAMVPLCHDFQS-------LAFYCCVFGFTIGAYVGLTSVILVD--LLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKS--------------------------------------ERKPHTEHLALS-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKG-----TVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFG---FGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAM-LLSIIGITNTVGRVFCG-WVADLPQVNSLL----LNNCCLLVSTIAVTLTPLCYSYAA-------YITMSIFFGLAISGYISLTSIILVD--LLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSE---------------------------------------ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7TM99-1", "uniprot_id": "MOT9_MOUSE", "id": "Q7TM99-1", "name": "Monocarboxylate transporter 9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFQKSP-----------------------------------------DGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQ-------------------------------------------TSDCPFPEKTAPENVPDRYSMYNEKEKNPEE---------------------------------------------------------------------------------------------------------TMNFQDKGYSSEDKCLPNGDWGRETSLPKSLA-------------------------------------------------------IAAHTKEPETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLG-ILADFKWINTLY----LYVATLIITGLALCAIPFAKSYVT-------LAILSGILGFLTGNWS-IFPYVTTK--TVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDMCN-----------------------------------------KKLPKPAVPTTFFY------KVASNV--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9P097-1", "uniprot_id": "A0A8M9P097_DANRE", "id": "A0A8M9P097-1", "name": "Monocarboxylate transporter 9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAVKSES--------------------------------------TLDGGWGWMIVVASFMAQFLSFGSPQSVGVLYPEWLSAFQEGKG-----MTAWVGSMVSGVALITSPVCSACVDNFGARPVTIFSGVMVAGGLMLSAFAPNISFLIFSYGIVVGMG---CGLVYAATLTITCQYFDKRRGLALGIVTTGTSVGGFIYATLQNELIELFGLEGCLLIIGALALNLMACAGPMRPLN-------------------------------------------LPGYYLKQRAALQRTEDPEPLYSKP---------------------------------------------------------------------------------------------------------------TAIIIESG--SDLKTKPGLAENTTTVKLLINK-------------------------------------------------------DPTELQDSEGERKVHILSSSIIARAIKKWMRPYGQYFCETVELLQDRVFMAFCIAMFLFSLGAFPPVLFMEDVAQSEGLIDGIALIPLVSIVAMTTGIGKLILG-VLADMRWVNSLY----LYALTLIGSGTALLLIPVSKSYLG-------LQILSAAVGFFSGNWS-LTSYITTK--IVGIERLGQAHGILMCFGGFGIALGPPVVGWFFDWTQSYDLAFYLSGTCVLVSGVFLFLAALPCWNRTAQE--------------------------------------GNSQAEEDVNTSQQHHSFDCDKVASVA--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQDTPSKRGAHTLRQRF--------------------------------------------------------------------------------------LVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDK-FKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIY----LQVLSFLLLGLMSMMIPLCRDFGG-------LIVVCLFLGLCDGFFITIMAPIAFE--LVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQ----------------------------------------------RMFK---KEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K1P8-1", "uniprot_id": "MOT8_RAT", "id": "Q8K1P8-1", "name": "Monocarboxylate transporter 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQDTPSKRGAHTLRQRF--------------------------------------------------------------------------------------LVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDK-FKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIY----LQVLSFLLLGLMSMMIPLCRDFGG-------LIVVCLFLGLCDGFFITIMAPIAFE--LVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVAFYFAGVPPIIGAVILFFVPLMHQ----------------------------------------------RMFK---KEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G8XYX6-1", "uniprot_id": "MOT8_DANRE", "id": "G8XYX6-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHSESDDNTAGGTPGSEDPQAEESSSPAEEFE-EQERKLAPEDSTVQLIHTG-------------------CTDKRPATPPGAHP-------GQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCG---SSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMPGMALDGGPSTPESASRWQKG--------------------------------------------------------------------------------------LAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQ-FGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIY----MQVASFILLGVMSMMIPQCAVFEG-------LVVVFVLMGLCDGCFITIMAPIAFE--LVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVAFYLAGVPPIVGGIVMFFVPLVHQ----------------------------------------------RMQKR-RKETDDPSMDKMLKN--CSNGDMLPGYTDMETHI-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3U9N9-1", "uniprot_id": "MOT10_MOUSE", "id": "Q3U9N9-1", "name": "Monocarboxylate transporter 10", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQEEP-AAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEV---------------------ELTRSAGS-EPPV---------------PPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKEKESGGSRSSFFSRRK--------------------------------------------------------------------------------------LSPPKKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKER-FQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVY----LQVLSFFFIGLMSMMIPLCSAFGA-------LIAVCLAMGLFDGCFISIMAPIAFE--LVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHS----------------------------------------------KKQRKISKNAGGEKMEKMLENQSSLLSGSSGIFKKDSASII----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y77-1", "uniprot_id": "MOT10_RAT", "id": "Q91Y77-1", "name": "Monocarboxylate transporter 10", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEV---------------------ELTRSTGNQEPPE---------------PPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKEKESEDSRSSFFSRRK--------------------------------------------------------------------------------------LSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKER-FKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVY----LQVLSFFFIGLTSMMIPLCSVFGA-------LIALCLIMGLFDGCFISIMAPIAFE--LVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHS----------------------------------------------KKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L1W9-1", "uniprot_id": "MOT10_DANRE", "id": "A1L1W9-1", "name": "Monocarboxylate transporter 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEPEPTLEQEPTPEPEPTQEPTPEPTPEPEPTQEPESEPELELKQE---------------------NGCTKASEQKSPEEFE------------PPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACG---CSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSSKPGSRCPPLSR----------------------------------------------------------------------------------------------IFNVNIWKSLGYRIWAFGIPAALYGYFVPYVHLMTHVEER-FGPEANKEVLLACIGITSGVGRLIFGRVADYVPGVNKVF----LQVSSFMVIGVMSMMIPLCHVFGG-------LIAVCLLMGLFDGCFICIMAPIAFE--LVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVAFYLAGIPPLIGGAVLCAIPWVEA----------------------------------------------RRKRREAANT-AENTEKMLESRSPPLEDTVCRTE-EPESVI----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWK0-1", "uniprot_id": "Q9VWK0_DROME", "id": "Q9VWK0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKKVYQDTTRPLPRVSRARYYN---------------KHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSS-----QITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFG---MGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQ---------------------------------------------------------------------------------LADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAG---------------------------------------------MESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTP-FILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRV-----FFLIGVVGIALGRTVVACTRSYSL-------ILCSFVWIGLCKGVRTIFWPLIIPG--YVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYD-YSVTLHCLNMMSFVAATSWSLEALIRRHRR-------------------------------------------KQRLVNS--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ0-1", "uniprot_id": "Q9VWJ0_DROME", "id": "Q9VWJ0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSS-----ELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFG---RGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVK----------------------------------------------------------------------------------------RDRDAEALQQVQPLAERED-----------QDEDIIKN---VVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEK---SDSNGHVELKRLSSKDSN---PGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELED-----------------------------------------------EKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTP-FILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRT-----FFVVGILGMCIGRMFLSMTSNFYV-------MMAIFLWLGLNKAFRTVFWSLIIPS--YVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTS-YAVTLNLLNALCVMAFAGWYLEDFIRARSR-------------------------------------------KSPPVKSIN------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ1-1", "uniprot_id": "Q9VWJ1_DROME", "id": "Q9VWJ1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTT-----GAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIG---VGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDE-------------------------------ELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNL-SYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAAL---------------------------------------------DEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTP-FFFANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRT-----IFLVSIIFVALTRSIMAEQTEWTQ-------LMIWLSICGFFRGSALSNFTLTVSE--YCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQS-------------------------------------------RRRTADAAQLPTQDVGATTTATSDQNDVKL---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E960-1", "uniprot_id": "Q0E960_DROME", "id": "Q0E960-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTF-----TAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFG---LGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLN------------------------------------------------------------------------------------------------PPAKHNNRK----------------------HIRLLTEADGEK----------------------------------------TSPLQVVIVPTNQSKIERSPPNVDTLCSRMG----------------------------------------------------------------------------------------QRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRV-----VFLIGIVGLFVARCVLAENQTLPV-------IITMSVLTGMMKSATVINNNLTISA--HCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPEILYRHR---------------------------------------------RQRCATNKSMETQSIDAAEVAKLNS--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K1C7-1", "uniprot_id": "MOT14_MOUSE", "id": "Q8K1C7-1", "name": "Monocarboxylate transporter 14", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLEN----------------------------------------------------------------------------------------------------------------------------------------------------------------CPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHP----------------------------------------------------RKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILG-AVADLPCISVWN----VFLIANFTLVLSIFLLPLMHTYAS-------LAVICALIGFSS-GYFSLMPVVTED--LVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQ--------------------------------------------------------SRRKCIEGAHV---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4LFF4-1", "uniprot_id": "A0A0B4LFF4_DROME", "id": "A0A0B4LFF4-1", "name": "", "aln": "MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSIS-----SVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVG---------------------------------------------------------------------------------------------------------------------------------MYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGP----IIGISNLVMRNILGILAYKRRSWTLG-----LCGCGLIFGGVSVLISAFYGENLIWF-----QFLYGFSYAVAPAVYSTLRGLIYVK--YLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRN-----------------------------------------------------------RMAQ-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGS--KLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFG---LAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRQHKRSYKFELLD-----------------------------------------------------------------------------------------------YDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSY-VSCMVSVGSLLGRPIVG-HIADKYGSLTVG-----MILHLVMAILCWAMWIPCKNLAT-------AIAFGLLVGSIMGTIWPTIASIVTR--IVGLQKLPGTFGSTWIFMAAFALVAP-IIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIAR----------------------------------------DEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :.* . . : . .. * : : :* . . . . . * * ", "identical_positions": 5, "similar_positions": 18, "identity": "0.45%" }, { "cls_id": "homologset.agr.SGD:S000001709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVP9-1", "uniprot_id": "MX2_MOUSE", "id": "Q9WVP9-1", "name": "Interferon-induced GTP-binding protein Mx2", "aln": "-------------------------------------------MVLSTEENTGVDSVN--------LPSGETGLGEKDQESV----NNLCSQYEEKVRPCIDLIDSLRALGVEQD--LALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTRCPLVLKLRKLN------------------------------------------EGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDRGTEDKVVDVVRNLVYHLKKGYMIVKCRGQQDIQEQLSLTEALQNEQIFFKEHPHFRVLLEDGKATVPCLAERLTAELISHICKSLPLLENQIKESHQSASEELQKYGMDIPEDDSEKTF-FLIEKINAFNQDITALVQGEENVAEGECRLFTRLRKEFLSWSKEIEKNFAK--GYAVLYNEVWAFEKQYRGRELPGFVNYKTFENIIRRQIKTLEEPAIEMLHTVTEIVRAAFTSVS---EKNFSEFYNLHRTTKSKLEDIRLEQEKEAEMSIRLHFKMEQIIYCQDQ-----------------------------IYRGALQKVREEEAE----EEKKTKHGTSSSSQSQD---------------------------------------------------------------------------LQTSSMAEIFQHLNAYRQEAHNRISSHVPLIIQYFILKMFAERLQKGMLQLLQDKDSCSWLLKEQSDTSEKRKFLKERLARLAQARRRLAKFPG------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20591-1", "uniprot_id": "MX1_HUMAN", "id": "P20591-1", "name": "Interferon-induced GTP-binding protein Mx1", "aln": "-------------------------------------------MVVSEVDIAKADPAAASHPL---LLNGDATVAQKNPGSVA--ENNLCSQYEEKVRPCIDLIDSLRALGVEQD--LALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTRCPLVLKLKKLV------------------------------------------NEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMF-FLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQE--GHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVS---IKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQ-----------------------------VYRGALQKVREKELE----EEKKKKSWDFGAFQSSS---------------------------------------------------------------------------ATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18588-1", "uniprot_id": "MX1_RAT", "id": "P18588-1", "name": "Interferon-induced GTP-binding protein Mx1", "aln": "-------------------------------------------MKERTSACRHGTPQK----------HPDTSEESQAMESV----DNLCSQYEEKVRPCIDLIDSLRALGVEQD--LALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTRCPLVLKLKQLK------------------------------------------QGEKWSGKVIYKDTEIEISHPSLVEREINKAQNLIAGEGLKISSDLISLEVSSPHVPDLTLIDLPGITRVAVGDQPADIEHKIKRLITEYIQKQETINLVVVPSNVDIATTEALKMAQEVDPQGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRVLLEDGKATVPCLAKRLTMELTSHICKSLPILENQINVNHQIASEELQKYGADIPEDDSKRLS-FLMNKINVFNKDILSLVQAQENISWEESRLFTKLRNEFLAWNDYIEEHFKKTLGSSEKHSQMEKFESHYRGRELPGFVDYKAFENIIKKEVKALEEPALNMLHRVTTMVKNAFTKVS---SNNFGDFLNLHSTAKSKIEDIRFNQEKEAEKLIRLHFQMEHIVYCQDQ-----------------------------AYKKALQEIREKEAE----KEKS----TFGAFQHNSP--------------------------------------------------------------------------RKELTTTEMTQHLNAYYQECGRNIGRQIPLIIQYSILQTFGQEMEKAMLQLLQDTSKCNWFLTEQSDSREKKKFLKRRLLRLDEAQRKLAKFSN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20592-1", "uniprot_id": "MX2_HUMAN", "id": "P20592-1", "name": "Interferon-induced GTP-binding protein Mx2", "aln": "MSKAHKPWPYRRRSQFSSRKYLKKEMNSFQQQPPPFGTVPPQMMFPPNWQGAEKDAAFLAKDFNFLTLNNQPPPGNRSQPRAMGPENNLYSQYEQKVRPCIDLIDSLRALGVEQD--LALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTRCPLVLKLKKQ-------------------------------------------PCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAEATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQKATEELRRCGADIPSQEADKMF-FLIEKIKMFNQDIEKLVEGEEVVRENETRLYNKIREDFKNWVGILATNTQK--VKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPALSMLQKAMEIIQQAFINVA---KKHFGEFFNLNQTVQSTIEDIKVKHTAKAENMIQLQFRMEQMVFCQDQ-----------------------------IYSVVLKKVREEIFNP---LGTPSQNMKLNSHFPSNE--------------------------------------------------------------------------SSVSSFTEIGIHLNAYFLETSKRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQSETATKRRILKERIYRLTQARHALCQFSSKEIH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH68-1", "uniprot_id": "MXA_DANRE", "id": "Q8JH68-1", "name": "Interferon-induced GTP-binding protein MxA", "aln": "------------------------------------------------------------------------------MEKLS---YTFSQQYEEKIRPCIDTIDNLRSLGVEKD--LALPAIAVIGDQSSGKSSVLEALSG-VPLPRGSGIVTRCPLELKMIRTK------------------------------------------DQDRWHGRISYKTCEEDFDDPAEVEKKIRQAQDEMAGAGVGISEELISLQITSADVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIRKFVTRQETINLVVVPCNVDIATTEALQMAQAEDPDGERTLGILTKPDLVDKGTEGTVVDIVHNEVIHLTKGYMIVRCRGQKEIMDQVTLNEATETESAFFKDHPHFSKLYEEGFATIPKLAEKLTIELVHHIQKSLPRLEEQIETKLAETQKELEAYGNGPPSEPAARLS-FFIDKVTAFNQDMLNLTTGEDVKCTTDLLLFPELRQEFAKWSHILDRSGDS--FNKKIEKEVDNYEVKYRGRELPGFINYKTFEGLVRDQIKLLEEPALKTLKTVSDVVRKKFIQLA---QCSFIGFPNLLKIAKTKIEGIKLNKESLAESMLKTQFKMELIVYSQDG-----------------------------TYSQSLKHAKDKLEEMEKERPQPKIKLPLLSSFDLGT--------------------------------------------------------------------------DNHATLREMRLHLKSYYTIASKRLADQIPMVIRYMLLQEAALELQRNMLQLLQDKDGVDNLLKEDCDIGQKRENLLSRQTRLIEGTQPLGHLLEVTFIDYCNILMQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DKF0-1", "uniprot_id": "MXC_DANRE", "id": "Q6DKF0-1", "name": "Interferon-induced GTP-binding protein MxC", "aln": "---------------------------------------------------------------------------MSSFDSAEGECNGLNQHYEKKVRPIIDLVDTLRALGVEKD--LNLPAIAVIGDQSSGKSSVLEALSG-VALPRGIGIVTRCPLILKLKKIT------------------------------------------RDKNWSGLLTYKDQTEILKEPTGIENAVLKAQIALAGTGEGISHEMITLEIQSCDVPDLTLIDLPGIARVATGNQPEDIEKQIKDLIEKFIKRQETISLVVVPANIDIATTEALKMASTVDPTGQRTLCILTKPDLVDRGMEDTVVRTVNNEVIRLEKGYMIVKCRGQQDINDKLNLVEALEKERRFFDEHPQFSSLLEDGKATIPLLGQRLTEELVEHIAKNVPRLQNQIEMKLQKTFERLKVLGESVPDDDEIELNNFLIKKLRQFMDALEEVKRVEEEPVKSDTRVFSKIRQEFVSWKHILDSKPIK------MSTDLQEYVRTHRGKELPGFLNYGTFAGIIRMHVEDLEEPALKLLRNAKDIVHSSVGSIA---NIHFNGYPNLLLAVKEPIEKCLHEQFQNAEEKIRSQFKLEKTVYCQDD-----------------------------LYTNHLNLLR----------PKNTVRFGLEASLGNS-------------------------------------------------------------------------------ELRETAFHLTSYLTIACERLANQIPLIVQYHMMNEYNSQLQNAMLGLIGTSD-PGMLLCEDSGVARIRKDLKERLERLKDARRALPKVVHSANSW-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3APM4-1", "uniprot_id": "A0A8M3APM4_DANRE", "id": "A0A8M3APM4-1", "name": "", "aln": "-------------------------------------------MSVSKQSVFSMFSSS--------FTSTRSSDDPKNSHYESQQMREVHSHLEESIRPYIDLIDTLRSVGIHKD--LALPTIVVIGDQSSGKSSVLETLSG-VALPRGNGIVTRCPLELRLKKVT------------------------------------------GGVSWKAVISYREKRTEFADPSMVERHVKTAQDELAGNGVGICDELITLEVMSPDVCNLTLIDLPGIARVPVAGQPDDIANQIKKLIIKFIVMQETINLVVVPCNIDIATTEALKLAQEVDPEGKRTIAVLTKPDLIDKGTEKNILAIVQNKVIPLRKGYVMVKCRGQQQIDDDISLDEATEMEKEFFQNHEFFRRLLSEDKATTKSLANKLTQNLVDHIKKSLPQLSEQIKKQLWDLRDDLKECESGPPQDSKGAKQ-FLIKILTKFNGRIKLLSSGEK---MAEKNLFVLLREEFNMWNDHLNETKKS---LKQSTKEKIEVLQNFRGRELPGFSNYRVFEVILQNHVATLKNPASKLLNAIKGIILDHFTEVV---ETCFQNYPNLQSITKDKIDNIQSSQQAKAEQRISEQFKMERMIFTQDP-----------------------------IFLKALNEIP----------DSETFSIDELPVFDKK---------------------------------------------------------------------------------SKYSDMLEAYYEIVVQRMADQLPMMILFFMLKQTAKLLTADMLSLLKGVK-VSELLFEDTDVSRRRRDLQARLDRLSIAQETLSNFEGSAE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21576-1", "uniprot_id": "VPS1_YEAST", "id": "P21576-1", "name": "Vacuolar protein sorting-associated protein 1", "aln": "-------------------------------------------------------------------------------------------MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKKKDESGKHQNEGQSEDNKEEWGEFLHLPG--KKFYNFDEIRKEIVKETDKVTGANSGISSVPINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNAANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTD--VIDILAGRVIPLRYGYIPVINRGQKDIEHKKTIREALENERKFFENHPSYSSKAH--YCGTPYLAKKLNSILLHHIRQTLPEIKAKIEATLKKYQNELINLGPETMDSASSVVLSMITDFSNEYAGILDGEAKELSSQELSGGARISYVFHETFKNGVDSLDPFDQ-----IKDSDIRTIMYNSSGSAPSLFVGTEAFEVLVKQQIRRFEEPSLRLVTLVFDELVRMLKQI--ISQPKYSRYPALREAISNQFIQFLKDATIPTNEFVVDIIKAEQTYINTAHPDLLK---------------------GSQAMVMVEEKLHPRQVAVDPKTGKP---LPTQPSSSK---APVMEE-----------KSGFFGGFF------------STKNKKKLAALESPP---------PVLKATGQMTERETMETEVIKLLISSYFSIVKRTIADIIPKALMLKLIVKSKTDIQKVLLEKLYGKQDIEELTKENDITIQRRKECKKMVEILRNASQIVSSV--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQE0-1", "uniprot_id": "Q9VQE0_DROME", "id": "Q9VQE0-1", "name": "dynamin GTPase", "aln": "--------------------------------------------------------------------------------------------MEALIPVINKLQDVFNTVGSDS---IQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSP--------------------LDDRENRSAENG--------TSNAEEWGRFLHTK---KCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTD--AIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRK--YPTLAT--RNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYG-EDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAG-----LSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * : .:* . : ** *.*:*.********:* : * **** ***** ** *:: * : : . :.. : :* . *. *.* : * .* **::****:::*.. .** :* :** :: :: ::* * * ..* *:*.::.*.:* ** * **: ::** **:* * : : : . . : * : * *.*::* . : : : * *:. : : *.: *. * ** . :* :. ::. . * .. :: . : : . : .: . * * * ::: : : :*: : : . : * . : : . * : . : :* . : :* : :: : :: : . : * :. * . . : . ", "identical_positions": 92, "similar_positions": 134, "identity": "10.44%" }, { "cls_id": "homologset.agr.SGD:S000001710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAN6-1", "uniprot_id": "D3ZAN6_RAT", "id": "D3ZAN6-1", "name": "polynucleotide adenylyltransferase", "aln": "-------MKEMSAN--TMLDSQRQQKHYGITSPISLACPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDISESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGVRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASAS-TEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKANN------------------------YVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKDGMKIEATHVKKKQLHHYLPAEILQKK-----------------KK-SLSDVSRSSGGL---------------QSKRSSLDSNCLDSSRDTDSGTPFNSPGSAHKPSNPDSPTGDAERSN-------AEPMAVIVEKLPS-----VPPAQGLSIPVIGAK--GDAAVKAVSSPAVCTIPTVVGRSVIPRVTTPHNPVQGQPHL----NGISNITKNVTPKRSHSPPTDGTAKRLKDIEKFIRLESAFKE-----SRAAEDRKRKPMDAIGG-ESMPIPTIDTSRKKRLPSKELPDSSSPVPASNIRVIKNSIRLTLNR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCL9-1", "uniprot_id": "PAPOG_MOUSE", "id": "Q6PCL9-1", "name": "Poly(A) polymerase gamma", "aln": "-------MKEMSAN--TMLDSQRQQKHYGITSPISLACPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDISESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASAS-TEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKANN------------------------YVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKDGMKIEATHVKKKQLHHYLPAEILQKK-----------------KK-SLSDVSRSSGGL---------------QSKRSSLDSTCLDSSRDTDSGTPFNSPVSANKPSNPDSPTGEIERSS-------AEPVAVVVEKLPS-----VPPAQGLSIPVIGAK--VDPTAKAVSSPAVCTIPTVVGRNVIPRITTPHNPVQGQPHL----NGISNITKNVTPKRSHSPPTDGTSKRLKDIEKFIRLESAFKE-----SRAAEDRKRKPMDSIGG-ESMPIPTIDTARKKRLPSKELPDSSSPVPANNIRVIKNSIRLTLNR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWT3-1", "uniprot_id": "PAPOG_HUMAN", "id": "Q9BWT3-1", "name": "Poly(A) polymerase gamma", "aln": "-------MKEMSAN--TVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASAS-TEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKDNN------------------------YVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKK-----------------KKQSLSDVNRSSGGL---------------QSKRLSLDSSCLDSSRDTDNGTPFNSP--ASKSDSP--SVGETERNS-------AEPAAVIVEKPLS-----VPPAQGLSIPVIGAK--VDSTVKTVSPPTVCTIPTVVGRNVIPRITTPHNPAQGQPHL----NGMSNITKTVTPKRSHSPSIDGTPKRLKDVEKFIRLESTFKD-----PRTAEERKRKSVDAIGG-ESMPIPTIDTSRKKRLPSKELPDSSSPVPANNIRVIKNSIRLTLNR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGL0-1", "uniprot_id": "A2BGL0_DANRE", "id": "A2BGL0-1", "name": "polynucleotide adenylyltransferase", "aln": "-------MREMSATGNSTLGGQQPRKHYGITSSISLAFPREIDHIYTQKLTEAMKPFGVFEGEDELNHRLAVLGKLNSFVKEWISEISESKNLPPSAVANVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERTDFFSSFFEKLKRHDEIKDLRAVEDAFVPVIKFKFDGIEIDLLFARLALQSIPDNLDLRGDSLLRNLDIRCIRSLNGCRVTDEILYLVPNKENFRLTLRAIKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAVAATLVHKFFLVFSKWEWPNPVLLKQPEDSNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTIMNEEFKNGLTVTDEILQGKADWSKLFEPPNFFQQYRHYIVLTASAS-TEENHLEWIGLVESKIRVLVGNLERNEYITLAHVNPQSFPGSKENRNEND------------------------FVSMWFIGISFKKLDNSDCVNIDLTYDIQSFTDTVYRQASNINMLKDGMTIEATHVKKKQLHHYLPPELVQRK-----------------KK-SLGDINRSSNGG---------------GSKRCSLDSSQLDSSRDTDIGTPFSSPTPISKPCQPASTPEDNSSSPP------QHPVLVFMDSPPASELSQPKPEQGMSIPVIGSKPITTPVAKPPTPPAGNTIPTVVGRSVIPRLAASSPELAN--------------SVNGAPKRPHSPSLEDPPKRHKDTEVFS-DDSAFKEPYPPSSNGLDGDEGQTVETLAETKAMPIPTIDTSRSQRLPSKELPDASSPIPTSNLRVIKNSIRLTLNR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61183-1", "uniprot_id": "PAPOA_MOUSE", "id": "Q61183-1", "name": "Poly(A) polymerase alpha", "aln": "--------MPFPVTTQGSQQTQPPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKESPDREE------------------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK------------------RKKHSTEGVKLT-----------------------ALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNS-------PAPAVTAAS-VTSIQASEVSVPQANSSESPGGPS-SESIPQTATQPAISPPPKPTVSRVVSSTRLVNPSPRPSG------NTATKVPNPIVGVKRTSSPNKEESPKKTKTEEDETSEDANCLALS-GHDKTETKEQVDLETSAVQSETVPASASLLASQKTSSTDLSDIP-ALPANPIPVIKNSIKLRLNR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G751-1", "uniprot_id": "A0A8I6G751_RAT", "id": "A0A8I6G751-1", "name": "Poly(A) polymerase", "aln": "--------MPFPVTTQGSQQTQPPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKESPDREE------------------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK------------------RKKHSTEGVKLA-----------------------ALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNS-------PAPAVTAAS-VTSIQASEVSVPQANSSESPGGPS-SESIPQTATQPAISPPPKPTVSRVVSSTRLVNPSPRPSG------NAATKVPNPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALS-GHDKTETKEQVGMETSAAPSEAAPASASLVASQKTSSTDLSDIP-ALPANPIPVIKNSIKLRLNR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51003-1", "uniprot_id": "PAPOA_HUMAN", "id": "P51003-1", "name": "Poly(A) polymerase alpha", "aln": "--------MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDKEE------------------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQK------------------KKKHSTEGVKLT-----------------------ALNDSSLDLSMDSDNSMSVPSPTSATKTSPLNSSGSSQGRNS-------PAPAVTAAS-VTNIQATEVSVPQVNSSESSGGTS-SESIPQTATQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALS-GHDKTEAKEQLDTETSTTQSETIQTAASLLASQKTSSTDLSDIP-ALPANPIPVIKNSIKLRLNR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVP6-1", "uniprot_id": "PAPOB_MOUSE", "id": "Q9WVP6-1", "name": "Poly(A) polymerase beta", "aln": "-------MMPFAVTTQGAQQPAPAPKQFGISSPISLAAPKDTDRELTQKLIETLQPFGVFEEEEELQRRILILQKLNNLVKEWIREISESRNLPQAVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRNDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDSFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMIEEFKQGLAITHEILLNKAEWSKLFEAPSFFQKYKHYIVLLASAP-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKETADKEE------------------------FRTMWVIGLVLKKPENSEILSIDLTYDIQSFTDTVYRQAINSKMFEMDMKIAAMHLRRKELHQLLPNHVLQK------------------KETHLTESVRLT-----------------------AVTDSSLLLSIDSENSMTAPSPTGTMKTGPLT--GNPQGRNS-------PALAVMAAS-VTNIQFPDVSLQHVNPIESSGIAL-SESIPQIPSQPTISPPPKPTMTRVVSSTHLVNHPSRPSG------NTATNIPNPILGV----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRJ5-1", "uniprot_id": "PAPOB_HUMAN", "id": "Q9NRJ5-1", "name": "Poly(A) polymerase beta", "aln": "-------MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLASAS-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDMEE------------------------FRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMGMKITAMHLRRKELHQLLPHHVLQD------------------KKAHSTEGRRLT-----------------------DLNDSSFDLSAGCENSMSVPSSTSTMKTGPLIS--SSQGRNS-------PALAVMTAS-VANIQATEFSLQQVNTNESSGVAL-NESIPHAVSQPAISPSPKAMVARVVSSTCLISHPDLQET---------QQQTYLIL------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B770-1", "uniprot_id": "A0A8M2B770_DANRE", "id": "A0A8M2B770-1", "name": "Poly(A) polymerase", "aln": "--------MPFPITSQ-VQTAQPTPKHYGITSPISLAPPKEADLVLTRKLTETLRPFGVFEEELELQRRILVLGKLNTLVKFWIREVSEAKNIPASVIDSVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERTDFFSSFYEKLKEQEEVKDLRAVEEAFVPVIKLAFDGIEIDILFARLALQTIPENLDLRDDGLLKNLDIRCIRSLNGCRVTDEILHLVPNIENFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAVAATLVHKFFLVFSKWEWPNPVLLKQPEDCNLNLPVWDPRVTPSDRYHLMPIITPAYPQQNSTYNVSASTRAIMVEEFKRGLAITDEILQNKADWSKLFEAPNFFQKYKHYIVLLASAQ-TEKQHLEWVGLVESKIRILVGNLEKNEFITLAHVNPQSFPGPKEGNDKEE------------------------FSTMWVIGIVFKKMEGSENLNVDLTFDIQSFTDTVYRQAITSKMFEQDMKITAMHVKRKQLHQLLPEVAIHRS-----------------KRKHSSDGVR-------------------------AMNDSNLDLSLDSDNSMSVPSPTGPS-AAKIARAPSPQGSTG-------TATNTSELQGKTEATGENTHLASVDGTSSSNASG-KEAAPPQSTSP-IQSEKKPSEQNPLPSPCLSAEPAVKRP--------ASALENEMTKKAKVEDLSAPEAKSSGETDGHVAPAQIVEVIPS-DGELKTETELMVEDT----------AEKVPLAQKTSNADLSDVP-VLPNNPIPVVKNSIKLRLSR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG96-1", "uniprot_id": "A0A0B4KG96_DROME", "id": "A0A0B4KG96-1", "name": "polynucleotide adenylyltransferase", "aln": "MWNSEPTHRQHHQHNGNSTSGGPPAKQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNTLVKQWVKEISVSKNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFEVLKKQPEVTECRSVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRSLNGCRVTDEILALVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAAATLVHKFFLVFSRWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVSESTKKVILTEFNRGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQ-TADDHLEWCGLVESKVRLLIGNLERNPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSMWFIGLEFER---SENLNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQLSLYLDSDFLKRERKSMESHNNFNNTLLANRKRLSTELAQSQDPLPPGQQPSSGNRGRDSGAKIQRLSDSLTEENSNASSDMGAGTPTTPTTAQLSAPSFKSSGKNGSEIDVVEQEPTQPHNNGNASSNTTTTEVACSXQPPTLHPHPPHQQPPPAPPQPPAHHHHHQKFRKNNNAAAAAASNSIFNQRSILHAASSLSAALSITGHKRKQQTATSTTMISSSNIAHSNYTQHSTHNNNGGGGGSHYNKTYYIDDDDEDNNQPLLTPNNQTQQQQKAVRITATS-ASPATSVPVAASAAPPAPTISL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29468-1", "uniprot_id": "PAP_YEAST", "id": "P29468-1", "name": "Poly(A) polymerase", "aln": "---------------------MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSYCCPTEDD-------------------------YEMIQDKYGSHKTETALNALKLVTDENKEEESIKDAPKAYLSTMYIGLDFNIENKKEK-VDIHIP----------------------------CTEFVN-----------------------------LCRSFNEDYGDHKVFNLALRFVKGYDLPDEVFDENEKR----------------------------------PSKKSKR---KNLDARHETVKRSKSDAASGDNINGTTAAVDVN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::..:* . . : . * :. . ** : * .*: :* *: :.: :: ::* :.:. . ****:*:******** *:***:* *.* :: * *:* * *: : : : .* :****:**: *.**.**:: *** :. .: * ... *:.** : :*:*** ******* ***: : **::**::****: : :*:* :*: ***:******* ******* ::.::.:**:::*.*:**:**:** :: *.. **:*:: ..** * **:******. :*.*:: **: :: ** .*: :*.:*: .: * .*:* .** :*:.:: : . : : .::*:* ******:*:*: .** * :** .: * :. * .: : :* . :. . . : .: : : :.* : : : . . . . . . ", "identical_positions": 155, "similar_positions": 165, "identity": "18.63%" }, { "cls_id": "homologset.agr.SGD:S000001711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B9EJ86-1", "uniprot_id": "OSBL8_MOUSE", "id": "B9EJ86-1", "name": "Oxysterol-binding protein-related protein 8", "aln": "-----------------------------------------------MEAALADGEPDRSSLLGDSKDVLGPSTVVANSDEP-----------------------------------QHLTPGKMSQRQGRDANPTPTRDLPQPSLSPASLHSQGF----------------------ERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMVREGKEHDLSISSDSTHVTLYGLLRANNLH-SGDNFQLNDSEIERQHFKDQDLYSDKSDKENDPEHDESDNEVLGKSEESDTDTSERQDDSYIDPEPVEPLK-----ETTYMEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWIHPR--------------------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGKLKLGKEVLATLEGHWDSEVFINDK---KTDNSEIFWNPTPDIKQWRLIRHTVKFEEQDDFESEKLWQRVTKAINAKDQTEATQEKYVLEEAQRQAARDRKTKTQEWVCKLFELDPLTGEWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKH----RTPMVSVPKMKHKPTRQQKKVVKGYSSP--EPDIQDSSGSEAQSV-----------------KPSTR--RKKGIDLGDIQSSIESIKQTQEEIKRNIMALRNHLLSS--TPATDYFLQQ---------------KDYFVIFLLILLQVIINFIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JXN8-1", "uniprot_id": "A0A0G2JXN8_RAT", "id": "A0A0G2JXN8-1", "name": "Oxysterol-binding protein", "aln": "-------------------------MEDLTGVRPQEFEIKLLLRGKIKIIHYSEVAEVQERLLGDSKDVLGPSTVVANSEEP-----------------------------------QHLTPGKMSQRQGKDAYPTPTREL-QPSLSPASLHSQGF----------------------ERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSGLLKRTMMRDGKEHDLSISSDSTHVTLYGLLRANNLH-SGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVLGKSEESDTDTSERQDDSYIDPEPVEPLK-----ETTYMEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKRVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWIHPR--------------------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGKLKLGKEVLATLEGHWDSEVFINDK---KTDNSEIFWNPTPDIKQWRLIRHTVKFEEQDDFESEKLWQRVTKAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWACKLFELDPLTGEWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKH----RTPMVSVPKMKHKPTRQQKKVAKGYSSP--EPDVQDSSGSEAQSV-----------------KPSTR--RKKGIDLGDIQSSIESIKQTQEEIKRNIMALRNHLLSS--TPATDYFLQQ---------------KDYFVIFLLILLQVIINFIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF1-1", "uniprot_id": "OSBL8_HUMAN", "id": "Q9BZF1-1", "name": "Oxysterol-binding protein-related protein 8", "aln": "-----------------------------------------------MEGGLADGEPDRTSLLGDSKDVLGPSTVVANSDES-----------------------------------QLLTPGKMSQRQGKEAYPTPTKDLHQPSLSPASPHSQGF----------------------ERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLH-SGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLK-----ETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWIHPR--------------------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDK---KTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQTKVKH----RTPMVSVPKMKHKPTRQQKKVAKGYSSP--EPDIQDSSGSEAQSV-----------------KPSTR--RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSS--TPATDYFLQQ---------------KDYFIIFLLILLQVIINFMFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ER64-1", "uniprot_id": "OSBL5_MOUSE", "id": "Q9ER64-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "---------------------------------------------------------MKEEAFLRRRFSLCPPASTPQKTDP-----------------------------------RKVPRNLLLGCENELGPITPGRDMESNGPSQP------------------------------RDEEPQTPGS-----ATKVPLAEYRLCNGSDKECTSPTTRVSKKDALKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALEN------DAFSDKSERENAEDSDAETQDHSRKTNESGSDLLD---------SPGGPWR-----GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLGKLSDYYYHGDLLSRAAAEDDPYCRMKLVLRWYLSGFYKKPKG--IKKPYNPILGETFRCRWLHPQ--------------------------------TNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGILYGTMTMELGGKVNIECEKNNLQAELDFKLKPFFGSSANINQISGKIMSGEEVLARLTGHWDRDVFIKEE---SSGGTELFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIREGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFLLDPLTQEWRYRYEDLSPWDPLKDIAQYEQDGILHTLQRETMSGQTTFLGSPDSRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGGESPCPRC-RREVHRLKMLQEAVLSIQEAQQELHRHLSTMLSSTVRAGQAPAPSLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZYG1-1", "uniprot_id": "A0A8I5ZYG1_RAT", "id": "A0A8I5ZYG1-1", "name": "Oxysterol-binding protein", "aln": "----------------------------MCREQRWALVCGQKRLELLAPQKPPSTHTMKEEAFLRRRFSLCPPASTPQKTDP-----------------------------------RKLPRNLLLGCENELGPITPGRDMESNGPSQP------------------------------RDEEPLTPGS-----ATKVPLAEYRLCNGSDKECTSPTTRVSKKDTLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGETVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALEN------DAFSDKSERENADDSDAETQDHSRKTNESGSDLLD---------SPGGPRR-----GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIKLVLRWYLSGFYKKPKG--IKKPYNPILGETFRCCWLHPQ--------------------------------TNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGLLYGTMTMELGGKVTIQCEKNNLQAELDFKLKPFFGSSTSINQISGKITSGEEVLARLTGHWDRDVFIKEE---ASGGTKLFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIHEGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFTLDPLTQEWRYQYEDYSPWDPLKDIAQYEQDGILHTLQRETMSGQTAFLGSPESRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGNESPCPRC-RREVHRLRMLQEAVLSIQEAQQELHRHLSAMLRSTVRAGQAPAPGLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0X9-1", "uniprot_id": "OSBL5_HUMAN", "id": "Q9H0X9-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "---------------------------------------------------------MKEEAFLRRRFSLCPPSSTPQKVDP-----------------------------------RKLTRNLLLSGDNELYPLSPGKDMEPNGPSLP------------------------------RDEGPPTPSS-----ATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP--KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESDTETQDHSRKT-ESGSDQSE---------TPGAPVRR----GTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHPQ--------------------------------TDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRA------EDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEE---GSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRC-RKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSP---------------RSWFLLCVFLACQLFINHILK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4JCZ0-1", "uniprot_id": "A0A0B4JCZ0_DROME", "id": "A0A0B4JCZ0-1", "name": "Oxysterol-binding protein", "aln": "---------------MQQPATPSTPVNNAPSATPSAASGPAASAPAVASSTPIRINSAKQQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSVPTGGHLLQLQAPLPSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSA-ADAAKLNRKESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLRSNSSTGTAPTSSYIGEPLPVSHETQWSEADYEKHFNDHDLDAD--------------SQNEAPNAVMSGLESESESDPAEPAQDDVVD-------------QQCV----ETSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKG--LKKPYNPILGERFRCYWQHP---------------------------------SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRG------ECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKETLATINGHWDKECRVKDS---KTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSYG-QWLYKYADLRPWDSRNDVRQYECQFKVLTQTRHK---SVPIVHGAEMIHPLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALIGLAFSLILRWLFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1LRE5-1", "uniprot_id": "F1LRE5_RAT", "id": "F1LRE5-1", "name": "Oxysterol-binding protein", "aln": "---------------------------------------------------------------------------MASIVEG----------------------------------PLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSR-----------------------RGCVRLRGAVIG---IDDEDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKDDEQRKKVETLKDTTNSMVESIKHCIVLLQIAKDQSNAEQHADGVLSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPAQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGNSPPSSSLTPPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLK---------RPDTTESLNSSMSNGTSDADLFDSHDDRDEDGEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPRDRMVQVVKWYLSAFHAGRRGSVAKKPYNPILGEIFQCHWTLPNDTEENAELVS--------------EGPVPWVSK-NSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLEYG------EHYILTFPNGYGRSILT-VPWVELGGECSINCSKTGYSANIVFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGIMYAKYA---TGENTVFVDTKKLPIIKKKVR----KLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC--WVYDEPLLKRLGTVKH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A8Z1-1", "uniprot_id": "OSBL9_MOUSE", "id": "A2A8Z1-1", "name": "Oxysterol-binding protein-related protein 9", "aln": "---------------------------------------------------------------------------MASIVEG----------------------------------PLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSR-----------------------RGCVRLRGAVIG---IDDEDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFIPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKDDEQRKKVETLKDTTNSMVESIKHCIVLLQIAKDQSNAEQHADGIISTINPVDAIYQPSPLEPVISTMPSQTALPPEPAQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGNSPPSSSLTPPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLK---------RPDTTESLNSSMSNGTSDADLFDSHDDRDDDGEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPRDRMVQVVKWYLSAFHAGRRGSVAKKPYNPILGEIFQCHWTLPNDTEENAELVS--------------EGPVPWVSK-NSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLEYD------EHYILTFPNGYGRSILT-VPWVELGGECNINCSKTGYSANIVFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGIMYAKYA---TGENTVFVDTKKLPIIKKKVR----KLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC--WVYDEPLLKRLGAVKH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "S4R1M9-1", "uniprot_id": "OSB10_MOUSE", "id": "S4R1M9-1", "name": "Oxysterol-binding protein-related protein 10", "aln": "MERAAQSTDGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGG-GSRSSPGSVAASPSGGGGRRREPALEG----------------------------------VLSKYTNLLQGWQSRYFVLDFEAGLLQYFVN-EQSKHQKP-----------------------RGVLSLSGAIVS---LSDEAPHMLVVYSANGEMYKLRAADSKEKQLWVTQLRACAKYHMEMSSKTTPGSRSRSLTLLPHGTPSSASP---CSQRHLSTGAPGVVSVTRHKSPAA-ARRAKSQYSG------QLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLS------------LLQQSVRQAAPPSHKPGASETILGWHGPTSHS---------------------TDQLKNG-TLGSLPSASANITWAILPNSAEEEHN---------SQPEPEPD-SGPELVLSEEEQSDNEDKGEVE--PGAMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKWTSPHPP------ISAHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHG------EEYVFTLPSAYARSILT-VPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYS---NGE-TKVIDTTTLPVYPKKLR----PLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEERQRVEERKRETLRTPWRPKYFIPEGDG--WVYFNPLWKTH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWM8-1", "uniprot_id": "F1LWM8_RAT", "id": "F1LWM8-1", "name": "Oxysterol-binding protein", "aln": "MERAAQSADGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGG-GSRSSPGSVAASPSGGGGRRREPALEG----------------------------------VLSKYTNLLQGWQNRYFVLDFEAGLLQYFVN-EQSKHQKP-----------------------RGVLSLSGAIVS---LSDEAPHMLVVYSANGEMYKLRAADSREKQLWVTQLRACAKYHMETSSKTTPGSRSRSLTLLPHGTPSSASP---CSQRHLSAGAPGVVSVTRHKSPAA-ARRAKSQYSG------QLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLT------------LLQQSVRQAGPPSHKPGASESILGWHGPTSQS---------------------TDQLKNG-TLGSLPSASANITWAILPNSAEEEHS---------SQPEPEPD-SGPELVLSEEEQSDHEDKGEVE--PGTVEDQHSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKWTSPHPP------ISCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHG------EEYVFTLPSAYARSILT-VPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYS---NGE-TKVIDTTTLPVYPKKLR----PLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEEKQRTEERKRETLRTPWRPKYFIPEGDG--WVYFNPLWKTH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI95-1", "uniprot_id": "OSB11_MOUSE", "id": "Q8CI95-1", "name": "Oxysterol-binding protein-related protein 11", "aln": "---------MQGGEPASVMKVSESEGKLEGLATAVTPN-----KNSGNSSCGGAISSSSSNSSRGGSAKGWQYSDHMESVNG----------------------------------YLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKP-----------------------RGTLQLAGAVIS---PSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLAS----SGNSP---ISQRRPSQNAMSFFNVGHSKLQS--VNKRAHLHPD------HLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDLLMLKATSMATMNCLNDCFH------------ILQL---QHASHQKGALPSGTTIEWLEPKIPL---------------------SNHYKNGAEQPFATEPN-KPMGAPEAQCVAESGV---------LAREPED-------ISADDEVEDTCDNKEDD--LGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLCLLEHG------EEYTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNLTNTVVCRVQGEWNSVLEFTYS---NGE-TKFVDLAKLAVTKKRVR----PLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLRTETGTPWKTKYFIKEGDG--WVYHKPLWK-------GIPSQPAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UVT3-1", "uniprot_id": "A0A8N7UVT3_DANRE", "id": "A0A8N7UVT3-1", "name": "Oxysterol-binding protein", "aln": "------------------------------MQTEAVLE-----HHSGSQSSG-----------RTG-SKSWQYSDLMEKVDG----------------------------------YLMKYTNLVTGWQYRYFVLNNEAGLLEYFVN-EQSRNQKP-----------------------RGSLPLGGAVIS---PSDEDSHTFTVNAISGEQYKLRASDAKERQHWVSRLQVCAQHHTEAMGKTNPPLQSRSLSMASQG--SGSSP---GSQHRISQNSNALLGLSQLQRGSSLYSSRKSLLPD------HLLEAREMMTQAQGQHRDLIQSIEGLPSSQGPSPLDQDLLLLKATSLATMTCLSDCLH------------ILQL---QQVARQKFPL-SGPALEWLEPKLP-----------------------DILKNGGTLPSITKDDGKTEGAVLEPLEMDSCD---------IVLEQEE-------IDATQEVDDSSPSEEED--LGAVEEERSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFVAITDGSSPMDRMVRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWNVPK-EAASPTG-------------IPKEG-SSCASDCYNVRFVAEQVSHHPPVSGFYAECQERQMCVNTHVWTKSKFMGMSIGVSMIGEGNLNLLEHG------EEYTFSLPSAYARSILT-VPWVELGGKVNVNCAKTGYSAVITFQTKPFYGGKLHRVNAEVKHNPTNAVVCRVQGEWNGVLEFAYT---SGE-TRFVDVTKLPVTRKRVR----PNELQGPYESRRLWQHVTESLKERDMDKATEHKRFLEERQRKEERHRAETQTPWRTKYFERKGEG--WMYYQPLWKTAGQSSSSVPSPQNP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02201-1", "uniprot_id": "OSH6_YEAST", "id": "Q02201-1", "name": "Oxysterol-binding protein homolog 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKKLTVGSDSHRLSKSSFSSNKSSHSATK------------------------------------------------------------------------------------------------DQPIDTDDID-------------------------------------------EDDESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKA--VKKPLNPVLGEYFTAYWDLPN---------------------------------KQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSPN--FQADIEFKTKGYVFGTYDAIEGTVKDYDGN-AYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESPLRPKVR----PLSEQGEYESRKLWKKVTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYKNIPVDEDPEKQIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKKMIENEKQNPAKQ--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : *. :.:: :: *:: * **:::.****:** :*:* :: . ::: . *. .:.:**:.:: :. *** **::** * . * * :::**.***** . :. : : . : .**:* * * .. * : * * * : * : :.:* :***. : . : : : *: * : . : *.*: .. :: . * **. **: *: : : **: * :*: ** : : * . * ", "identical_positions": 66, "similar_positions": 90, "identity": "6.07%" }, { "cls_id": "homologset.agr.SGD:S000001712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWG9-1", "uniprot_id": "D3ZWG9_RAT", "id": "D3ZWG9-1", "name": "", "aln": "VERPALPGSSGAGRGRALVHSPRPPGAHARFRQAERGWDCRARPAGRYQDAWRVSVGERPRRATSERGVFALPGASLELWQLFSPLPSAGVRLPGGPLLWGSVPWRRLSGCIQDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYR---------TRKQWLHKDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLSPVKDLHLGKLALTKFPKSPETWIHRRWVLQQLSQETSLPSSVAKGSLG-VVPAERTQRIIQEEMEVCSEAAGRYPSNYNAWSHRIWVLQNVAKLDLKILLDELSSTKHWASVHVSDHSGFHYRQFLLKSLISQTTTDNAVPQHNSLKCEPKE----AAAAAASAEEPSVSLPQLLEEEVEFCTDLIDSYPGHETLWCHRRHVFYLQHHLNGRLPPSLTPLSPADCSGAALNDLHQIPTSPQLSQAMEVDGLSDSSKQG-YSQETKRLKRTPAPDSLGLEMEHKFIDQVLSTCRNVEQARYANAYRKWLVTLSQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A494B9V8-1", "uniprot_id": "A0A494B9V8_MOUSE", "id": "A0A494B9V8-1", "name": "", "aln": "-------------------------------------------------------------MAESNEEVAVL------VQRVVKDITNAFRRNP-----------------HIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYR---------TRKQWLNKDELADVTCTLLLLNPDFTTAWNVRKELILSGTLSPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLSQETFLPSSVAKGSLG-AVPAERTQRIIQEEMEVCSEAAGRYPSNYNAWSHRIWVLQNVAKLDLKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTTIDSAVPQHNSLKSEPK-----DEAAAASTEEPSVNLPQLLEEEVEFCTDLIDSYPGHETLWCHRRHVFYLQHHLNGRLPPNLTHLSPADCPGGALNDSLQIPTSPQLSQAMEVDGLSDSSKQG-YSQETKRLKRTPAPDSLGLEMEHRFIDQVLSTCRNVEQVRYANAYRKWLVTLSQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6K3-1", "uniprot_id": "PTAR1_HUMAN", "id": "Q7Z6K3-1", "name": "Protein prenyltransferase alpha subunit repeat-containing protein 1", "aln": "-------------------------------------------------------------MAETSEEVAVL------VQRVVKDITNAFRRNP-----------------HIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYR---------TRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGNLG-TIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHLN---------------------------AGSQLSQAMEVDGLNDSSKQG-YSQETKRLKRTPVPDSLGLEMEHRFIDQVLSTCRNVEQARFASAYRKWLVTLSQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPW7-1", "uniprot_id": "PTAR1_DANRE", "id": "A3KPW7-1", "name": "Protein prenyltransferase alpha subunit repeat-containing protein 1", "aln": "-------------------------------------------------------------MAESEEEVDVL------VQRVVKDITNAFKRNP-----------------NIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYR---------QRKQWLDREALVDITSTLLLLNPDFTTAWNVRKELLQCGVLNPEKDLYLGKLALSKHPKSPETWIHRRWVLQRLQKECSPSGQELKDSAESRRQCERLQRALQEEMRVCAEAAGRYPSNYNAWSHRIWVLQNMAKGNLKVLHDELSSTRLWVSMHVSDHSGFHYRQHLLKALAKELSPAAEKDVHTSQQPNGE-----NTATASDDNHHKDVMPRLFHEEIQLCTDLIESYPGHETLWCHRRHVFYLWHQWRREHMQGAGSQSPALTHTDVLLS-KELCDNNSISQAMDIDCVLDGSKHGSYTQDTKRLKRGPLLLQPGFPSEHTFISRILTGCRNPEQSRFAIAYRKWLDSVIGQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W501-1", "uniprot_id": "Q9W501_DROME", "id": "Q9W501-1", "name": "", "aln": "-------------------------------------------------------------MEEERNEKKVL------CEKIIRDINAVFLKDQ-----------------DLASFEIIP-KEANCNKSPVVHVEHNLGLESWCAQHVYDHAHRTLISHRRQTTAQQLRTLQQQQQSDSLAKYLNVALLINPDVTTFWHIRRQLVQKNRLSINKELQFSALVLSIKPKSNEAFAYRRWLYSFQSADAIDWPN---------------------EIGICERAADRCASNYHAWSHRQWILQNGP----CLLQSELLRTEKFMRKHISDYSCYHYRQVLLS-RAYELSFALPKDSGASGSSTLASLQHLMTSYGLECEANAEDLLGLLLPHVDLSS--VSKQRLISFLYCCNVAANDMRLCAEQRLMYGSR-------------------DCFELHRRAALKFIVEQCVRLQMGLPNGQLLPVASGDLRSHLGNFDFEDNPFLSAVRREESTLGGKHRRWCNLHLSFGYPAD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02202-1", "uniprot_id": "ECM9_YEAST", "id": "Q02202-1", "name": "Protein ECM9", "aln": "-------------------------------------------------------------MQSSLP----------LCREFFEKITAYL---------------------DYHDFRLTITANQPSITLPYYVDEKAHSIELIIFKTTFLSLFQEAHTYFN-----KTFSDQSGISNENIYYMTVGFLLTTPENKTVYNVHEDLLKR-YFQDNSVLVIPDLLVKEVRLIQRLLCSSNNRINKSSSLWILYRKLFVLSLD------ANTLVLPDILFVFHSSGSQHFSNYYCWNTARWFYDNLP---YNKRIELFNLTKRFCFQNVKDCSSWSALAYMVCQQEEKKTDNIRDFQRLT------------SSFNVPFKINKVDLNFQVQPADAFTQELVKWIDRTYAADWPPYLCLLQITKFN-----------------------------ITLRIEMDSVLLTWRNEILNFEENSGHIKMINNTPIVPEKFSNDLLTSVNFAHFGYKKLFLNKFLDKNKKEQSDS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : .: : : * *: .:* : .. : :. : : ** .*: .* ::::.:*: :. . * : * :. . . . : : :..: *** .*. *. :: . . : *. : ::.* * : :: : . : : . : :. . : : . :: . : :: : ", "identical_positions": 18, "similar_positions": 79, "identity": "3.4%" }, { "cls_id": "homologset.agr.SGD:S000001716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VC36-1", "uniprot_id": "Q9VC36_DROME", "id": "Q9VC36-1", "name": "", "aln": "-MLSRKRRASSISSRQDEDPLQLDDSTPEQSPVQQTTTQSARKKRRLDPTELCQQLYDSIRNIKKEDGSMLCDTFIRVPKRRQEPSYYDVVVNPIDLLKVQQKLKTDSYDDLDDLMADLELLIGNAKAFYIPGSSEHQDAVSLWQHIHSQRQRIMEANGLAEEEPRARRMSRQVRRMTSSTEPGGDGATDDEYNQYEELFASVMTATDPVGDR--LMHRMFQLLPSKKIYPDYYDVIEHPIDLRLIATKIQMNAYSSLAEMERDLLQMTKNACLFNEPGSQIYKDAKSLKRIFTQRRIELEMGK-GKLAKRVKS-------------------LSSAAIAALKEEVDSSDDEETSKKGEGPMWALFDHLYNAPGTSEHPGVTGPPLGNSLWKLPVRRFHPEYFELIKRPISMSQIHTKLKKGDYANISDLTADLYLMLDNAKKAFPTSHRTHKDALKMLKLMNAKLVEESLEEGSDLDDEDAEEMDTEVFTVSTQPEKRKPGRPRINSNSNSNASHTPNNSNSPKSNRIAINAAIKKKILSIQKYLVDYSLGNRRPIEMFMEKPPRKIYPDYYDIIQNPIDMNTIEHNIRTDRYAAVEDVVSDYRLMFSNCRQYNEEGSNIYEDANILERALNEKLKEFPGLTEGKKSQQKYSKVG-------RKLKTAVITERLWQFYETVKEYQEPKGKRQLSLIFTKLPSKSEYPDYYDIIREPIDMDRIAQKLKQGAYDTLDDLAADFLLMLENACKYNEPDSQIYKDALVLQQLTLQLKQQLR-TERDSLPDVPLAVQELFLTLFTTIYNHQDEEGRCYSDSLAELPEYDEIGEGPKVRGISLDLVKRRLDKGAYKRLDVYQEDIFACLERARKLSRTDSDIFQDSIELQTYFIRKRDELCK--DTLSSSALNFSLERLMADVELCRQQKMQQEEQDQEQDKEKDEFNAAKGE-----------------SMTINQQVFSPGDYVYVQMPE-NKIPSICCIERLWTSPTNEKLMQASIFVRPHETYHVTTRKFLEKEVFKSSLSQTISMDKVQGMCYVMNIKDYIKMRPENLPEKDVYVCESRYNIQGRWFKKLKSWPPVREGSSVKFVPREQPLELKRVMSVFKERLEKHKG--ELEELKLQETLVEKEKPNVSCDPPPNAEVGSTYYQQYNTICSGAIKTGDFVYVATQTGKQ-SVAQVQQIWEQNGKSYFKGPWLLPPSETTPGLGKQFYRQELLLSTVEEVSPVVGIVGRCAVLEYSEFISSRPTEISESDVYICESVYDELKKALRKLVTGNMRKFQHSPSVTEDEIFYFKTPIKPSKD-------------------FKNELNELG------MLEDSMDGDTPSLSSDIAAMS-SPAPSVNSTPLTSKVKAAKSAKKCLTGYILYSSEVRKSICQSNPDATFGDISRMVGTEWKNLPSSVKQSWEDRASRQNEETAALRRELDDVQNSASPSSQVSQDVFGQVLTFECQWDKCDFQFEELSDCTEHCMSDSTGHIQRHPQAGVETEYVCLWRNCPRVKKSVQAFPNVLRLIKHVREVHLSKCGKTISAADRSKNFVPRRQKHAQLATTVPIPPSLAQSPRAPSNLEAVQLQQQQHPQQNMHQLQQQQTIVLGPPPEPLFVTVPPRTTRVIHSEAYIKYIESLQTGSHLNVVTCNNNWRRALTHITPAQVVAKTALPEKWIGPNLRDQGNVVQALCHLRNFMVDDILQIRRSCN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F8D8-1", "uniprot_id": "E7F8D8_DANRE", "id": "E7F8D8-1", "name": "Protein polybromo-1", "aln": "MMGSKRRRATSPSSSVSGG--DFEDSQSTSISSTSRKRRRIANIPTVDPIAVCHELYNTIRDYKDDQGRMLCELFIRAPKRRNQPDYYDVVSQPIDMMKIQQKLKMEEYDDVEQLTSDFQLLFSNAKTYYKPETPEYRAACKLWDLYIRTKNEFVQRGDYDEDDDDD-----------DPQENLGGATEEESMSSLKEVLGMLLDAVLTYTEHGRLISELFQRLPSKMQYPDYYAIIKEPIDLKSIAHRIQMCYYKSVNHMAKDIDLLVKNAKTYNEPGSQVFKDANTIKKVFAQKKLELEHSEPIKCSIRIRNRRFAHGDRLSCITTALQYGSESEEDAILTGSVHYDEVESEAESIHSSMDVSNPIFQMYEAVRGVRNSQGQLLAEPFFQLPSRKDYPDYFQQISHPVSLQQIRSKMKNNEYESVEQIDTDLNRMFENAKRYNVPSSQIYKRVLKLQHILQMKRKELTRRDDEDGD-------------------------------SRLSSTLSDGGSTKRKSHKKNTKKNRMKALLAAVAETREMGTG-RRLCDLFMVKPSKKDYPDYYKIILEPMDMRIIEHNIRSDKYPNEDSMMEDMKLMFRNARHYNEEGSRVYNDANILEKILREKRKELGPPPDDDEIVSPKLKIRKSGISPKKSKYLTPLQQKLNELYEAVKNYTDKRGRR-LSTIFLRLPSRAELPDYYVAIKKPIDMEKIKSHMLANKYQDVDALVEDLVLMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGGDDAHVPDVARLIQELVRNLFVSVLGHQDDEGRCYSDSLAEIPAVDPN--CSDKTPLNFEIIRANVDKGRYRRLDVFQDQMFEVLEKARRLHRTDSEIFEDSVELQQFFIRIRDELCKNGEILLTPALSYTIKHLHSDVEKEKKEKLPKEYEEDKLKREEEKKEAEKSEDTAGGGWQGALQRNYSQDCSFKDNMYHVGDYVYVEPTEPNLQPHIVCIERLWQDDAGENWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKIPVSKILGKCVVMFVKEYFKLQPDSFRPEDVFVCESRYSAKTKSFKKIKMWTMP--LSSVKFVPREVPLPVVRVASMFAPKQESEKPPEVTEDDKALPSVIDKEKEDITLEVN-NGEPGCQYYEQLCYNN-IWLKVGDCVYIRSHGLVRNRVGRIEKMWVRDGAAYFFGPIFIHPEETEHEPTKMFYKKEVFLSNLEESCPMTCIGGKCTVSSFKDFLSCRPTEMPEEDVLLCESRYIESEKQMKKFKG--LKRFSLSAKVVEDEIYYFRKLIVPQKEPSPLLEKKIEELEAKFADMTDEELDDLGDDDGDGSDAHCMPQLQTQLSGDMDMLHYAPQQSVPKSIKGLSKKEGAKRKINMSGYILFSSEMRAVIKAQHPDFSFGELSRLVGTEWRNLEATKKAEYEERAAKVAE------QQERDRAHQGSPRAGTPAGLLMGVVPLPTPMGLVPMAGMLGSFRPPMFTCQGPGMINMPPHP------------------------------------------MGLPALPLNFPWGLPGMPFHGMNGMAPGSTGSAYGTQMGGMNSGQQVPPPYPGQGQVGQPAHQQ------PSTPMFVAPPPKPQRLLHSEAYLKYIEGLSAESTT--VSKWDQTLSARRKDVRLTKEQESRLPSHWLKS-KGAHKTMADALWRLRDLMLRDTLNIQHTYNIHNI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02206-1", "uniprot_id": "RSC4_YEAST", "id": "Q02206-1", "name": "Chromatin structure-remodeling complex subunit RSC4", "aln": "-MVVKKRKLATEAGGSDER----PKYLPGKHPKNQEKTPHVDYNAPLNPKSELFLDDWHIPKFNR---------FISFTLDVLIDKYKDIFKD-------------------------------------------------------------------------------------------------------------------------------FIKLPSRKFHPQYYYKIQQPMSINEIKSR-DYEYEDGPSNFLLDVELLTKNCQAYNEYDSLIVKNS---------------------------------------------------------------------------------------------------------------------MQVVMLIEFEVLKAKNLKRNYLINSEVKAKLLHYLN--KLVDATEKKINQALLG---------------------------------------------------------------ASSPKNLDDKVKLS-----------------------EPFMELVDKDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYFN--------------------------------------YLIQKEFFPELQDLNE-RGEINLEFDKFEFENYLAIGGGGPAAAGALAISALDNDIEP------ESNREDLIDQADYDFNHFEGLGNGYNRSLLTEDYLLNP------------------------NNFKKLIAKPETVQSEVKNERSTTSDIEKTN----------SLESEHLKIPKYNVIKSMQKEMQS-------LSEQHTMEYKPYKLIQQIYIFSSKNLYS-----------QATKPLLGSRPSCNQNWVEYIFNGNELSQNEN---------------------------------------------------------------------AFSFMLQPMQTFLTLQSHLTS-----------------------------------SLKDTETLLTINKEPVKSRTSNVNSNLSQP-----------------------------------QQQENDVIGNDTKQDIENLTIGGGNNNDIVGNDNDKRNNIT-------------------------------------------------------------------------------------EIFDIRLSEGLNHLMFRCEDKIS-----------------------HETEFMNFWINVLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::*: :: :. . . . . . . . ::* * . : ** . .* *:. : * ***: :*:** *:.*:.:. * : : .. .: *: :.**. :** .* : *:: : :.:. :::* : :* .:: :.* :: * .. : : * :.. *. : : ** :. *:**.*: .*: : :::*:. .:*. ..: * *:* *.: :*: .: :*:**. * . :. ::: ::: : :*. *. .: . . .: :. : ..: : *:: : .: * . *: :*: .. *: . * .: : : .:. : . : .: .:. *. :. *.:: * . .: :: :* :* .:* . : : * .. .:: : : :: .:::: . : :* :*: :: . .: :. : .: : : : . . :: . . .:: ::: * : :: :::. * :* : : **. * *: * : * ", "identical_positions": 75, "similar_positions": 232, "identity": "4.32%" }, { "cls_id": "homologset.agr.SGD:S000001717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97852-1", "uniprot_id": "DHB4_RAT", "id": "P97852-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MASP---LRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEIRRRGGKAVANYDSVEA-GEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQRVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR-KRNQPMTPEAVRDNWVKICDFSN--------------------------------------ASKPKSIQESTG--------------------------GIIEVLHKIDSEG-ISQN------------------------------------------------------------------------------------------HTGQVASADASGFAGVVGHK------------------------------------------------------------------------------------------------------------------------------------LPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQKSLMSGG---LAEVPGLSINFAKVLHGEQYLELYKP-LPRSGELKCEAVIADILDK-GSGIVIVMDVYSYSGK--ELICYNQFSVFVVGSGG------FGGKR-TSEKLKAAVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIMLSQKLQMILKDYAKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51660-1", "uniprot_id": "DHB4_MOUSE", "id": "P51660-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MASP---LRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVAEIRRKGGKAVANYDSVEA-GEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR-KRNQPMTPEAVRDNWEKICDFSN--------------------------------------ASKPQTIQESTG--------------------------GIVEVLHKVDSEG-ISPN------------------------------------------------------------------------------------------RTSHAAPAATSGFVGAVGHK------------------------------------------------------------------------------------------------------------------------------------LPSFSSSYTELQSIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQKSMMNGG---LAEVPGLSFNFAKALHGEQYLELYKP-LPRSGELKCEAVIADILDK-GSGVVIVMDVYSYSGK--ELICYNQFSVFVVGSGG------FGGKR-TSEKLKAAVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISNAYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTVAAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51659-1", "uniprot_id": "DHB4_HUMAN", "id": "P51659-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MGSP---LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEE-GEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR-QKNHPMTPEAVKANWKKICDFEN--------------------------------------ASKPQSIQESTG--------------------------SIIEVLSKIDSEGGVSAN------------------------------------------------------------------------------------------HTSRATSTATSGFAGAIGQK------------------------------------------------------------------------------------------------------------------------------------LPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGG---LAEIPGLSINFAKVLHGEQYLELYKP-LPRAGKLKCEAVVADVLDK-GSGVVIIMDVYSYSEK--ELICHNQFSLFLVGSGG------FGGKR-TSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXJ0-1", "uniprot_id": "DHB4_DROME", "id": "Q9VXJ0-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MSSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEAVADYNSVID-GAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIESAAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSK--------------------------------------AKHLGAIAEASG--------------------------TLLEVLEKLKEGG----------------------------------------------------------------------------------------------------GDAIEDAFE-------------------------------------------------------------------------------------------------------------------------------------------------FNSKELITYALGIGASVKNAKDMRFLYENDADFAAIPTFFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEIVDD-LPTSGTLLTNGKVFDVMDK-GSGAVVVTNSESFDESG-RLLVRNQSTTFIVGAGK------FGGKKDPIAGVVPLQPAPNRQPDATVQYTTSEDQAALYRLSGDKNPLHIDPQMALLAGFKTPILHGLCTLGFSVRAVLAQFADNNPALFKAVKVRFSGPVIPGQTLRVDLWKQGTRINFRTVVVETGKEVISGAYVDLKSS--------------QAKL--------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02207-1", "uniprot_id": "FOX2_YEAST", "id": "Q02207-1", "name": "Peroxisomal hydratase-dehydrogenase-epimerase", "aln": "MPGN---LSFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPEKIVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFN-PDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAISKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTIFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSGYVSIKETIEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHSSKELDDGLFKYTTKDCILYNLGLGCTS---KELKYTYENDPDFQVLPTFAVIPFMQATATLA---MDNLVDN-FNYAMLLHGEQYFKLCTPTMPSNGTLKTLAKPLQVLDKNGKAALVVGGFETYDIKTKKLIAYNEGSFFIRGAHVPPEKEVRDGKR-AKFAVQNFEVPHGKVPDFEAEISTNKDQAALYRLSGDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYG-----PYEELKVRFTNVVFPGDTLKVKAWKQGSVVVFQTIDTTRNVIVLDNAAVKLSQA--------------KSKL--------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * :..**.::****.***: *** :*.*** *:****** * * .. *** ** **:: ** ***:*:** * *:::**:. ***:*:::******** *: : ::.:: : *** *.:: ::**: :*:.*::***: *:* :*::*****.**:***:*::**.:::. ** : *: * *.* * ****: ::* :.: * *: :.*:* :* *** : ... :* .**: :*: * * :.. .. * * : * :: * . ..: : : * ::* : *: * : .* :. : * * **:*.: *:::: **...** :*** *: : . .::: ******::: :* * * . :::** *.. ::: . ::. . .*: *: : *: *: .**: . : .: ** :*. :********** ******* :* . * .********:*:*.: :: ::. :: :*.**: * **:**:.. **:*. : *:* . *:..* *.* : :: : ", "identical_positions": 202, "similar_positions": 192, "identity": "19.4%" }, { "cls_id": "homologset.agr.SGD:S000001721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CYL5-1", "uniprot_id": "GAPR1_MOUSE", "id": "Q9CYL5-1", "name": "Golgi-associated plant pathogenesis-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKSASKQFNNEVLKAHNEYRAQHGVP-PLKLCKKLNREAQQYSEALASTRILKHSPESSRGQ-CGENLAWASYDQTGKDVADRWYSEIKSYNFQQPGFTSGTGHFTAMVWKNTKKIGVGKAS-ASDGSSFVVARYFPAGNIVNQGFFEENVPPPKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZJ62-1", "uniprot_id": "A0A8I5ZJ62_RAT", "id": "A0A8I5ZJ62-1", "name": "Golgi-associated plant pathogenesis-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKSASKQFNNEVLKAHNEYRAKHGVP-PLKLCKKLNQEAQQYSEALASTRILKHSPESSRGQ-CGENLAWASYDQTGKEVADRWYSEIKSYNFQQPGFTSGTGHFTAMVWKNTKKIGVGKAS-ASDGSSFVVARYFPAGNIVNQGFFEENVPPPKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4G4-1", "uniprot_id": "GAPR1_HUMAN", "id": "Q9H4G4-1", "name": "Golgi-associated plant pathogenesis-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKSASKQFHNEVLKAHNEYRQKHGVP-PLKLCKNLNREAQQYSEALASTRILKHSPESSRGQ-CGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKAS-ASDGSSFVVARYFPAGNVVNEGFFEENVLPPKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI35-1", "uniprot_id": "Q9VI35_DROME", "id": "Q9VI35-1", "name": "SCP domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MFLVNILIVLALC---------LLVLVIADLQEDHLNEHNRLREKHGSP-PLTLDDELTKGCEEYAKVLANNEKLEHS--SSAGQNYGENLCMRS--QTPLQCVQDWYDEIADYDFEKPQFAMSTGHFTALVWKNAKKMGIGQAK-DKKGYYWVVARYYPPVNVN--GQFEENVLPPIKGEGDENGQGNLNRFQVDNIPIIVMLWLCWQFTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QEP8-1", "uniprot_id": "A0A8M9QEP8_DANRE", "id": "A0A8M9QEP8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------------------------SSFEAEFLQVHNAYRKQHGAP-PLTFNKNLCRSAQQWAEHLLSTKTLAHS-NKGYGENLYYAWSSANKKLTGHEAVDSWYGEIKDYNFSRPGFSSKTGHFTQVVWKDTKELGVGLAT-DGN-TIFVVGQYLPAGNIANAGYFEKNVLPTGSKLDQKSTGATHKVEQAHGSSGIHSNKVPSVPHIAEKPTPEGKAESSFEAEFLQTHNAYRKHHGAPPLTININLSRSAQKWAEHLLSIRTLMHSNGDHGENVYYAYNSANKKLTGREAVESWYNEIKEYNFSRPGFSSKTGHFTQVVWKDSKELGVGLATDGSTSFVVGQYLPGGNITNAGYFERNVLPGGSKVDLKATPPVDKVGQARGALSITSNLLPSSSHSVGPAPPKTHSPQSSHSESESLFQFRQSLLKAVNDYRRQHGAKPLSLCPVLSKEAQDWAAHLASIGALQNSRKGYGETLSYKWTSSMVPPTGKEVAENWYKDNVKYNFAIPGFQKGTGNFTQMIWRSSEQVGVGLGSDGKGMFITVAFYNPSGNITNPGFFQDNVRPSGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IVU8-1", "uniprot_id": "A0A0R4IVU8_DANRE", "id": "A0A0R4IVU8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------------------------ASFKQEFLQTHNQYRHQHQAP-PLVYREDLCRAAQKWAEHMLSKKSLGHS-ETENGENVYYSFSSVKKTPTGKEAVDSWYSEIKDYNFAKSGHQPKTGHFTQVVWKSSKELGVGLAT-DGN-TVFVVGQYKPAGNITNAGYYEQNVLPKKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQA7-1", "uniprot_id": "Q9VQA7_DROME", "id": "Q9VQA7-1", "name": "SCP domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MSA-------------------------QQFEQEVLQAHNLYRAKHGAQ-PLTLSPKLNRLATEWANYLLSRNRMEHRQNSGYGENIYMASG---GNLKGADAVRSWYEEIRQYNWNSPSFQGNTGHFTQVVWKSSTELGVGFAK-SGS-TIYVVCNYNPPGNYNN--LFRENVAPPMQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQA2-1", "uniprot_id": "Q9VQA2_DROME", "id": "Q9VQA2-1", "name": "SCP domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAKRNVAPIPKTHERPPGPRGQDTKGNNELFLKEVFNTTNKYRAMHGCP-AVTINAALNKLAQEWANHLRDQNTMAHRPNPKYGENIFLSGG---MDVTGDLPVEMWYREINSYDFNKAQFVPTAGHFTQLIWKSSVEMGSGVAR-KAD-RTWVVCNYNPPGNVVG--LFKDNVPPKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36110-1", "uniprot_id": "PRY2_YEAST", "id": "P36110-1", "name": "Protein PRY2", "aln": "MKFSKVSLLAASASVALSAPVAVTVTQHVHQAATVVVQGIVRVENGQTLTTFITKGTQTASASPVATTSAPIVVANAQVDSIATSVIQESAVVAESATFEESSTETSEAFSTATATIQAVQTSASATQDDVTTTLTSSTQPTSTTTPTTTTTSPTTTTSPTTTASPTTTASPTTATTTQSTASSTQSSSSDFSTSMVNEHNTKRALHKDTGSLTWSDTLATYAQNYADSYDCSGNLVHS-GGPYGENLALGYG-------TTGSVDAWYNEITSYDYSNPGFSESAGHFTQVVWKGTSEVGCGLKSCGGEWGDYIICSYKAAGNVIG--EFADNVMPLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: * * * .: * . :::. : * *: . ** ** .*:: . . :**** ::**.: ::* * . ::: * .. * : .** * ", "identical_positions": 24, "similar_positions": 34, "identity": "3.27%" }, { "cls_id": "homologset.agr.SGD:S000001722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61020-1", "uniprot_id": "RAB5B_HUMAN", "id": "P61020-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPS-IVIALAGNKADLANK--------------------RMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRG--------VDLHEQSQQNKSQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61021-1", "uniprot_id": "RAB5B_MOUSE", "id": "P61021-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPS-IVIALAGNKADLANK--------------------RMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRG--------VDLHEQSQQNKSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L1J8-1", "uniprot_id": "A1L1J8_RAT", "id": "A1L1J8-1", "name": "small monomeric GTPase", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPS-IVIALAGNKADLANK--------------------RMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNPGGAAGRSRG--------VDLHEQAQQNKSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQD1-1", "uniprot_id": "RAB5A_MOUSE", "id": "Q9CQD1-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN-IVIALSGNKADLANK--------------------RAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRG--------VDLTEPAQPARSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RC99-1", "uniprot_id": "RAB5A_RAT", "id": "M0RC99-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPN-IVIALSGNKADLANK--------------------RAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLPKNEPQNPGANSARGRG--------VDLTEPAQPARSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20339-1", "uniprot_id": "RAB5A_HUMAN", "id": "P20339-1", "name": "Ras-related protein Rab-5A", "aln": "---------MASRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN-IVIALSGNKADLANK--------------------RAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRG--------VDLTEPTQPTRNQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35278-1", "uniprot_id": "RAB5C_MOUSE", "id": "P35278-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPN-IVIALAGNKADLASK--------------------RAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTRG--------VDLQESNPASRSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNK1-1", "uniprot_id": "B0BNK1_RAT", "id": "B0BNK1-1", "name": "small monomeric GTPase", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPN-IVIALAGNKADLASK--------------------RAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRNRG--------VDLQESNPASRSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51148-1", "uniprot_id": "RAB5C_HUMAN", "id": "P51148-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPN-IVIALAGNKADLASK--------------------RAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRG--------VDLQENNPASRSQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXV7-1", "uniprot_id": "A0AB32TXV7_DANRE", "id": "A0AB32TXV7-1", "name": "small monomeric GTPase", "aln": "---------MSTRG-TGRANGNLPQTKICQFKLVLLGDMAVGKSSLVLRFVKGQFDEFQETTIGAAFLAQSVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVFDITKPETFERAKAWVKELQRQASPN-IVIALAGNKADLADK--------------------RLVEYEEAQTYAEDTGLLFMETSAKTAMNVNELFLAIAKKMPKTDTQNP-MHAVRHRG--------VNLQDPDAQSTRSCCGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3I2-1", "uniprot_id": "RAB5_DROME", "id": "Q9V3I2-1", "name": "Ras-related protein Rab5", "aln": "MATTPRSGGASGTGTAQRPNG-TSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIE--------DTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPN-IVIALAGNKADLSNI--------------------RVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPKNDGANNQGTSIRPTG--------TETNRP----TNNCCK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36018-1", "uniprot_id": "YPT52_YEAST", "id": "P36018-1", "name": "GTP-binding protein YPT52", "aln": "---------------------------MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQSITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKARNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEAKQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVDINLQRPSTNDPTSCCS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9H0T7-1", "uniprot_id": "RAB17_HUMAN", "id": "Q9H0T7-1", "name": "Ras-related protein Rab-17", "aln": "---------MAQAHRTPQPRAAPSQPR--VFKLVLLGSGSVGKSSLALRYVKNDFKSILP-TVGCAFFTKVVDVG--------ATSLKLEIWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGEVLVMLVGNKTDLSQE--------------------REVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQELLQ--RSDEEGQALRGDA--------AVALNKGPARQAKCCAH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******. :*****:. *:**. *.. *:*.**::: : : . :*:*********:*:*:. :*:*.*:**::*:** . ::: :*: *:.:*..: . ::: * ***.**.. * : :*.: :*:. *** *.*** *.::* :.::: . : * . .** ", "identical_positions": 64, "similar_positions": 68, "identity": "24.43%" }, { "cls_id": "homologset.agr.SGD:S000001724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR86-1", "uniprot_id": "MIC60_RAT", "id": "Q3KR86-1", "name": "MICOS complex subunit Mic60", "aln": "MLRACQLSGVTVAAQSCLCG-KFVLRPLRPCRRYSTSSSSGVTAGKIAGAG-----------------------LLFVG--GGIGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPIQSGPLKISSVSEVMTDSELPMAQTQETNGDTPASA-AGD---------------PAPEVEHEDTINTECPNTDEGTSTFVT--------------------------------AALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAHAHRRIDQLNRELAQQKATEKQHIELALERQKLE-EKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMP----TIPLGSAVEAIRVSCSDN-EFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLAGRVAMIDETKNSLYQ----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CAQ8-1", "uniprot_id": "MIC60_MOUSE", "id": "Q8CAQ8-1", "name": "MICOS complex subunit Mic60", "aln": "MLRACQLSGVTVAAQSCLCG-KFVLRPLRPCRRYSTSSSSGLTAGKIAGAG-----------------------LLFVG--GGIGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPVQSGPLKISSVSEVMKDSKLPVAQSQKTKGDTPASA-ASTGAAQIISAAGDTLSVPAPAVQHEDTIKTECPNTNEGKSTSETTEEAFSSSVRERPPEEVAARLAQQEKQEQVEMESLAKSLEDALNRTSSVTLQTITAQNAAVQAVKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLE-EKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMP----TIPLGSAVEAIRVNCSDN-EFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQLKPPAELYP-----EDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16891-1", "uniprot_id": "MIC60_HUMAN", "id": "Q16891-1", "name": "MICOS complex subunit MIC60", "aln": "MLRACQLSGVTAAAQSCLCG-KFVLRPLRPCRRYSTSGSSGLTTGKIAGAG-----------------------LLFVG--GGIGGTILYAKWDSHFRESVEKTIPYSDKLFEMVLGPAAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLKTDHPEIGEGKPTPALSEEASSSSIRERPPEEVAARLAQQEKQEQVKIESLAKSLEDALRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLE-EKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETP----TIPLGSAVEAIKANCSDN-EFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQLKPPPELCP-----EDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91928-1", "uniprot_id": "MIC60_DROME", "id": "P91928-1", "name": "MICOS complex subunit Mic60", "aln": "MYRLAVRDQCKCALQRTLQQTTANNRQFGGSSSGSGGREQGRRQQEEQGQQGDQGYQGYQSLPPHMREAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQEEPPFKGITKNVNDQIDKVKSGIETVTSTVDSVTSKVTGLFGGGSGDDKSKK-----------SKVEPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKD----------------NPLPRDVVELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGE--NSLWTTLKNRASARDTAVATAERAAREAQEKIVACEIALSAAAT---AQNAKKVEAVRDKIKKLVDHIGNVKDELYRHKDTASVSDKYWRNVEKARNYFIDEIESIFP-------GLSLADKKLNLSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLKRAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLAT-----------EKANYKLQLAGMLGKLRGMDAALAERADAERTANQAQALWAACQALWASVRAATPGVHYKDRLRPLKNEINAIAKVAKGD-DLVAAVLESVPKEAQERGVYPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKLDTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAASGLLYL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36112-1", "uniprot_id": "MIC60_YEAST", "id": "P36112-1", "name": "MICOS complex subunit MIC60", "aln": "-MMLRTTASRKIVLRRGLAS-------------------------------------------------------------INTGTTVASKKASHKFRN----------TLWTIALSATAFYAGG-----------------------IIYSQKNDKFGDFFSNN------------------------------------------------------------------------------VPFAEDLLETYEHYHDRPTLFLEDS-------------------------------WDGLKAKSNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSLN--DSNLSIPESEFNSIKKSNQNMLTNLSQLNETLK------------EALSNYMIQRTSEVITELNTQYENSKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANEVGLLSITQVKEFN----KIIKDKIEKERNGRLAHLEEINSEVN-DLSKSIDRSSKILSKN----------EALVQLTFQVDEIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEGKISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPNSGILGQLTAKVFSLFLFTKTGNPSNATDFDS------------VYARVGDNLRVSNLNDAVEEVVSLKGWPHKVCESWIEDARRKLEVQRLVEILDCEIRTL----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * * .: * . .**: .: :.* . :: *. .. .:...: : . . : * :: . ..: : : . :*:: : . . : ::.:: :. .:: :. . .: . : . : :. :::: :.: : : : :::* . .: : : . .. : : . :: . :: ... : :: ::.:: .: *:.:: : :*. .:.: . . .::: .::.. : . . . * : : . . :.. .. .: . : . : : .:: : *: : ::: * ", "identical_positions": 15, "similar_positions": 158, "identity": "1.89%" }, { "cls_id": "homologset.agr.SGD:S000001725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1K5-1", "uniprot_id": "ARI1_MOUSE", "id": "Q9Z1K5-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDD-DEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGG--PGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPS---------------------KKSRTR-QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZSJ6-1", "uniprot_id": "A0A8I5ZSJ6_RAT", "id": "A0A8I5ZSJ6-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDD-DEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGG--PGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPS---------------------KKSRTR-QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4X5-1", "uniprot_id": "ARI1_HUMAN", "id": "Q9Y4X5-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDE-DDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPS---------------------KKSRTR-QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFJ9-1", "uniprot_id": "ARI1_DANRE", "id": "Q6PFJ9-1", "name": "E3 ubiquitin-protein ligase arih1", "aln": "MDSDEGYNYEFDDEEEE--------CSEDS-GEEETADDTLELGEVELVDP-VVAGGERD--DCGETGGSG---LGPG----------------QDEEDYRFEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLDKLFSECHVINPS---------------------KKSRTR-LMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHSCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCK-CGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRSTLMFTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYDKDLWEYIED---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NW85-1", "uniprot_id": "ARI1L_DANRE", "id": "Q6NW85-1", "name": "E3 ubiquitin-protein ligase arih1l", "aln": "MDSDEGYNYEFDDEEEEEEEE--EECSVDS-GEEEAVDDSLELGEVELLDP-AVAGGEPD--DCADTGGGG---PGPG----------------QEDEDYRFEVLTTEQILQHMVECIRDVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLDKLFSECHVINPS---------------------KKPKTR-PMSTRSSSQDLPCQICYLNYPNSYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHNCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCK-CGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRSTLMFTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94981-1", "uniprot_id": "ARI1_DROME", "id": "Q94981-1", "name": "E3 ubiquitin-protein ligase ariadne-1", "aln": "MDSDN--DNDFCDNVDS--------GNVSS-GDD--GDDDFGM-EVDLPSS---ADRQMD------------------------------------QDDYQYKVLTTDEIVQHQREIIDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPF---------------------NATEAI-KQKT-SRSQCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAE----------PRRVHCK-CGHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYASVKQKMEEMQQHN-MSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKK-NNQSMIFEDNQKDLESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVLLKHVHEGYDKEWWEYTE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT94-1", "uniprot_id": "Q9VT94_DROME", "id": "Q9VT94-1", "name": "RBR-type E3 ubiquitin transferase", "aln": "MNSEMEFSDEDHGDSHRS-------LLTHM-SCENDSDSEDTCTEILLPEN----SNSPE------------------------------------TEDFVYKVLSVDQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPF---------------------EKKIERESAASTSCAIPQLCGICFCSC--DELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAE----------PRAVLCK-CGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQSLKMENKLYSNIQAKMDDMQEE--MSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMN-NNQKIIFEDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREGYENDWWEFKEETTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z1K6-1", "uniprot_id": "ARI2_MOUSE", "id": "Q9Z1K6-1", "name": "E3 ubiquitin-protein ligase ARIH2", "aln": "MSVDMNSQGSDSNEEDYDPNCEEEEEEEED-PGDIEDYYVGVASDVEQQGA-----DAFD------------------------------------PEEYQFTCLTYKESEGALHEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYR-SNSAQLLVEARVQP-------------------------NPSKHVPTAHPPHH---CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDG-VGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPR----------ARRVQCNRCSEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYERIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMES-GPRKKLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHDT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJB8-1", "uniprot_id": "D3ZJB8_RAT", "id": "D3ZJB8-1", "name": "E3 ubiquitin-protein ligase ARIH2", "aln": "MSVDMNSQGSDSNEEDYDPNCEEEEEEEED-PGDIEDYYVGVASDVEQQGA-----DAFD------------------------------------PEEYQFTCLTYKESEGALHEHMTSLASALKVSHSVAKLILVNFHWQVSEILDRYR-SNSAQLLVEARVQP-------------------------NPSKHVPTAHPPHH---CAVCMQFVRKENLLSLTCQHQFCRSCWEQHCSVLVKDG-VGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPR----------ARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMES-GPRKKLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHDT--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95376-1", "uniprot_id": "ARI2_HUMAN", "id": "O95376-1", "name": "E3 ubiquitin-protein ligase ARIH2", "aln": "MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGA-----DAFD------------------------------------PEEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYK-SNSAQLLVEARVQP-------------------------NPSKHVPTSHPPHH---CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDG-VGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPR----------ARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMES-GPRKKLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHDT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76924-1", "uniprot_id": "ARI2_DROME", "id": "O76924-1", "name": "Potential E3 ubiquitin-protein ligase ariadne-2", "aln": "MDSDIEMDMESDNDGEYDD--------------DYDYYNTGEDCDVERLDP-----KRAD------------------------------------PEYFEYECLTVEDIEKLLNERVEKLNTILQITPSLAKVLLLEHQWNNVAVVEKYR-QDANALLVTARIKPPSVAVTDTASTSAAAASAQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQG-ISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEIS----------AKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFN--CKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCRYTLQYTYPYAYYMEA-GSRKNLFEYQQAQLEAEIENLSWKIERAETTD-----LGDLENQMDIAEKRRTTLLKDFFPVDA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36113-1", "uniprot_id": "HEL1_YEAST", "id": "P36113-1", "name": "E3 ubiquitin-protein ligase HEL1", "aln": "MSSGTENDQFYSFDESDSSSIELYESHNTS-EFTIHGLVFPKLISVTSQDSEFDINEDEDGVDTIYEGMLDAPLTKNNKRILCEG----------SVPNLSYECLTTKGIFERMLQRVDHLQPIFAIPSADILILLQHYDWNEERLLEVWTEKMDELLVELGLSTTAN--------------------IKKDNDYNSHFREVEFKNDFTCIICCDKKDTETFALECGHEYCINCYRHYIKDKLHEG-----NIITCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCN-SFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWVLSHTKECPKCSVNIEKNGGCNHMVCSS--CKYEFCWICEGPWAPHGKNFFQCTMYKNNEDNKSKNPQD-ANKTLKKYTFYYRLFNEHEVSAKLDWNLGQTLGTKVHALQERIGISWIDGQFLSESLKVLNEGRTVLKWSFAVAYYSDASHNLTKIFVDNQMLLANAVESLSELLQ-IKTPEVIMKRRPEFYNKAGYVENRTTALMECGRELLCKGICKAAE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : .: : : *: . : : : . ::* ...*: :.: : :. : .* * * :* *: : . * : . : : : : ** :* :: . . *: . *** * * *..* *:.*. .:** *:: :**:**:* : ***:****** * . *: :***:* * * .**. ::.*. :.:: . : . :: :* .* . : :* * ::: : : ::. . :**: *:* .: :* : * .* ::: *:* . :* :* : * ** :: : . .. : :.* .*: ", "identical_positions": 71, "similar_positions": 118, "identity": "11.91%" }, { "cls_id": "homologset.agr.SGD:S000001726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0VGK2-1", "uniprot_id": "TT39C_RAT", "id": "Q0VGK2-1", "name": "Tetratricopeptide repeat protein 39C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFGASFVSFLNAMMTFEE-----EKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDARKSTPSMVDRLQRQIIIADCQVYLAVLSFVK------------------------------------QELSAYIKGGWILRKAWKIYNKCYVDINALQELHQKTLTEEP--LSSDAANDNHIVAEG--VTEEALSRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLTYASESKDMKAPLATLALLWYHT------------VVRPFFALDGSDNKGGLDEAKAILLR----------KESAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLT----------AVCQGATG------DVDGAQLIFKEVQKLFKR-KNNQ---IEQFSVKKAERFRKQTP-------TRALCVLASIEVLYLWKALPNCSLPN------LQRMSQACHEVDDSSV-------VGLKHLLLGAIHKCLGNSQDAVQFFQRAAK-----------DESCRQNNSYVQPYACYELGCLLLDRA--ETVARGRTLLLQAKEDFSGYDFENRLHVRVHAALASLRELVPQ-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE09-1", "uniprot_id": "TT39C_MOUSE", "id": "Q8VE09-1", "name": "Tetratricopeptide repeat protein 39C", "aln": "-------------------------------------------------------------------------------------------------MAGSEE-----------QWPRRREDGDP---DAAAAPLQDAELALAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAMMTFEE-----EKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDARKSTPSMVDRLQRQIIIADCQVYLAVLSFVK------------------------------------QELSAYIKGGWILRKAWKIYSKCYVDINALQELYQKKLTEEP--LASDAANDNHVVAEG--VTEESLSRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLTYASESKDMKAPLATLALLWYHT------------VVRPFFALDGSDNKGGLDEAKAILLR----------KESAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLT----------AVCQGATG------DVDGAQLVFKEVQKLFKR-KNNQ---IEQFSVKKAERFRKQTP-------TRALCVLASIEVLYLWKALPNCSFPN------LQRMSQACHEVDDSSV-------VGLKHLLLGAIHKCLGNSQDALQFFQRAAR-----------DELCRQSNSYVPPYACYELGCLLLDSA--ETVGRGRTLLLQAKEDFSGYDFENRLHVRIHAALASLRELVPQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N584-1", "uniprot_id": "TT39C_HUMAN", "id": "Q8N584-1", "name": "Tetratricopeptide repeat protein 39C", "aln": "-------------------------------------------------------------------------------------------------MAGSEQ-----------QRPRRRDDGDSDAAAAAAAPLQDAELALAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAMMTFEE-----EKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDVRKSAPSMVDRLQRQIIIADCQVYLAVLSFVK------------------------------------QELSAYIKGGWILRKAWKIYNKCYLDINALQELYQKKLTEES--LTSDAANDNHIVAEG--VSEESLNRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLMYASESKDMKAPLATLALLWYHT------------VVRPFFALDGSDNKAGLDEAKEILLK----------KEAAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLT----------AVCQGATG------DVDGAQIVFKEVQKLFKR-KNNQ---IEQFSVKKAERFRKQTP-------TKALCVLASIEVLYLWKALPNCSFPN------LQRMSQACHEVDDSSV-------VGLKYLLLGAIHKCLGNSEDAVQYFQRAVK-----------DELCRQNNLYVQPYACYELGCLLLDKP--ETVGRGRALLLQAKEDFSGYDFENRLHVRIHAALASLRELVPQ-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXE6-1", "uniprot_id": "TT39C_DANRE", "id": "Q1LXE6-1", "name": "Tetratricopeptide repeat protein 39C", "aln": "-------------------------------------------------------------------------------------------------MAGPDS-----------PQQQQ--------VEEKAEQIDDAELAFQGINMLLNNGFRESDELFRRYRTHSPLMSFGASFVSFLNAMMTFEE-----EKMQMASDDLRTTEKLCESDNAGVIETIRNKIKKSMDSGRSGVEIVDRLQRQIIVADCQVYLAVLSFVK------------------------------------QELSAYIKGGWILRKAWKMYNKCYSDISQLQEACRRRSSDQQGALASDQANHNTSTGSGGRVTDEVLDRLKGSVSFGYGLFHLCISMVPPHLLKIVNLLGFPGDRHQGLASLAYASESKDMKAPLATLALLWYHT------------VVQPFFALDGSDSRAGLLEAKAILQK----------KAMVYPNSSLFIFFKGRVQRLECQINSALASFQDALEFASDQREIQHVCLYEIGWCSMIEMSFEDAFRSFERLKNESRWSQCYYAYLT----------GVCQGASG------DLEGAKGVFRDVQKLFKR-KNNQ---IEQFALKRAEKLRKVSL-------TRELCILGVVEVLYLWKALPNCSSSK------LQLMNQVLQGLDDQSS-------IGLKHLLLGAIQKCLGNIKDALQSFQLAAQ-----------DEYGRLNNSYVQPYACYELGCVLLAKP--ETLSKGRSLLLQAKENYAGYDFENRLHVRIHSALASIKEVVPH-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2ACP1-1", "uniprot_id": "TT39A_MOUSE", "id": "A2ACP1-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "-------------------------------------------------------------------------------------------------MGQK----------------GHKDSLYDCKGSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP-----QDILLAGNMMKEAQSLCQR--HRRKSSMTDSFSNLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQ-----------------------------------DENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYSKGE---------------------------SHR--HFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHT------------FLTFVLGTGNVN----IEEAEKLLKP----------YLNRYPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMK----------AAYLSMFGKEDYKPFGDNEVELFRAVPGLKLK-IAGKSLPTEKFAIRKSRRYLSPN---------PISLPIPALEMMYIWNGYAVIGKQPTLTDGMLEVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISA-----------NEKKIKYDHYLIPNALLELALLFMEQG--RNE-EAIKLLESAKQNYKNYSMESRTHFRIQAATLQARSSLEDGNRSLVSSVSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7D5-1", "uniprot_id": "F7F7D5_RAT", "id": "F7F7D5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MAFLTTW----------------KRAASRKRDRRSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP-----QDILLAGNMMKEAQSLCQR--HRRKSSVTDSFSSLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQ-----------------------------------DENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYSKGE---------------------------SHR--HFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHT------------FLTFVLGTGNVN----IEEAEKLLKP----------YLNRYPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMK----------AAYLSMFGKEDYKPFGDDEVELFRAVPGLKLK-IAGKSLPTEKFAIRKSRRYLSPN---------PISLPIPALEMMYIWNGYAVIGKQQKLTDGMLAVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISA-----------NEKKIKYDHYLIPNALLELALLFMEQG--RNE-EAIKLLDSAKQNYKNYSMESRTHFRIQAATLQARSSLGDGSRSPVSSVSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SRH9-1", "uniprot_id": "TT39A_HUMAN", "id": "Q5SRH9-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "-------------------------------------------------------------------------------------------------MGQK----------------GHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP-----QDILLAGNMMKEAQMLCQR--HRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRALHDPSHACSCPPGPGRQHLFLLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGE---------------------------NHP--HFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHT------------FLTFVLGTGNVN----IEEAEKLLKP----------YLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMK----------AAYLSMFGKEDHKPFGDDEVELFRAVPGLKLK-IAGKSLPTEKFAIRKSRRYFSSN---------PISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSISA-----------NEKKIKYDHYLIPNALLELALLLMEQD--RNE-EAIKLLESAKQNYKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5Y5-1", "uniprot_id": "TT39A_DANRE", "id": "A1A5Y5-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "-------------------------------------------------------------------------------------------------MSTG----------------KNAP---VTENSRQMSLQACLDECMEALDLFLNNHFNESLDKLRPRSKESMYHALIYATVLEMQAMMTFQQ-----DDIVHAGNTMKSAQEVCQR--FRKKS------GGLGSRGANDDLSEEQIHAEVCYAECLLHRAALTFLQ-----------------------------------DENMVSFIKGGIKVRNSYLIYKELHAFIQSDATFKGP---------------------------NHK--HLEGGVSFGIGAFNLTLSLFPARILKLLEFAGFSGDKEFGISQLYTGATSHTLRSMLCALLLLCFYT------------FLSFILGTGEGE----VEEAERLLKP----------FRLRYPRGAIFLFFAGRAEEIKGNIDEAVALFEDGCKAQQVWKQFHHMCYWELMWCFTFKRYWKMAYFYADLLSQESRWSKAMYVYMK----------AAYLSMLPDSESRPFGDNEVDLFRQVPTYKQK-IAGKSPPTEKFAIRKARRYKASN---------PVRLPVPVLEMMYMWNGFSMISKQPELTEGMMETLLEAERTLRASPDNEYTVDDTCLIQLLKGLCLKNQGQMQAAEDCFNQVYI-----------SEKKLKFDHYLVPNALLEMSLLFIDTG--RKE-QAIKLLQKAKNNYKVYSMESRTQFRVHAALTKLKADVSD--QEEITAL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BYY4-1", "uniprot_id": "TT39B_MOUSE", "id": "Q8BYY4-1", "name": "Tetratricopeptide repeat protein 39B", "aln": "------------------------------------------------------------------MALVGSRVELDADEDIFEDALETISRS-PSDMATSGFHFVPCETKRTSRQLGASAMGRPEGSSAKVDLKSGLEECAEALNLFLSNKFKDALELLRPWAKESMYHALGYSTIVVLQAVMTFEQ-----QDIQNGISAMKDALQTCQK--YRKKCTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQ-----------------------------------DENMINFIKGGLKIRTSYQIYKECLSILHVIQKNKQE---------------------------QHFFYEFEGGVKLGTGAFNLMLSLLPARIIRLLEFIGFSGNRDLGLLQLREGASGSSMRSPLCCLTILAFHT------------YISLILGTGEVN----VVEAESLLAP----------FLQQFPNGSLILFYHARIELLKGNTEKAQETFRKCISVQEEWKQFHHLCYWELMWIHIYQQNWMQAYYYSDLLCKESKWSKATYVFLK----------AAILSMLPEEEVAATKENVVSLFRQVDGLKQR-IAGKSLPTEKFAVRKARRYSPPSG-------VPGKLVMPALEMMYVWNGFSIVGKRKDLSENLLVTVEKAEEALQNQDFTDYSVDDECLVKLLKGCCLKNLERPLQAELCFNHVVE-----------SEKLLKYDHYLVPFTLFELAFLYKSQG--EID-KAIKVLETARNNYKDYSLESRLHFRIQAALHLWKKPSTD-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZC96-1", "uniprot_id": "TT39B_RAT", "id": "D3ZC96-1", "name": "Tetratricopeptide repeat protein 39B", "aln": "------------------------------------------------------------------MALVGSRVELDADEDIFEDALETISRS-PSDMATSGFHFVPCDTKRTSRQLGAPAVGRAEGSSAKVDLKSGLEECAAALNLFLSNRFKDALELLRPWAKESMYHALGYSTIVVLQAVMTFEQ-----QDIQNGISAMKDALQTCQK--YRKKCTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQ-----------------------------------DENMINFIKGGLKIRTSYQIYKECLSILHVIQKNKEE---------------------------QHFFYEFEGGVKLGTGAFNLMLSLLPARIIRLLEFIGFSGNRDLGLLQLREGASGSSMRSPLCCLTILAFHT------------YISLILGTGEVN----VAEAESLLAP----------FLQQFPNGSLILFYHARIELLKGNAEKAQETFRKCISVQEEWKQFHHLCYWELMWIYIYQQNWMQAYYYSDLLCKESKWSKATYVFLK----------AAILSMLPEEEVAVTKENVVSLFRQVDGLKQR-IAGKSLPTEKFAVRKARRYSPSSG-------VPGKLVLPALEMMYVWNGFSIVGKRKDLSENLLVTVEKAEEALQNQNFTDYSVDDECLVKLLKGCCLKNLQRPLQAELCFNHVLE-----------SEKLLKYDHYLVPFTLFELAFLYKSQG--EID-KAIKVLETARNNYKDYSLESRLHFRIQAALHLWKKPSSD-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VTQ0-1", "uniprot_id": "TT39B_HUMAN", "id": "Q5VTQ0-1", "name": "Tetratricopeptide repeat protein 39B", "aln": "MDAVLACRLRGRGNRVAALRPRPRPGGSAGPSPFALLCAGLSPEPRAGVGSEFPAWFLGGSSQRRNMALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSS--SSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQ-----QDIQNGISAMKDALQTCQK--YRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQ-----------------------------------DENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQ---------------------------QEFFYEFEGGVKLGSGAFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHT------------YISLILGTGEVN----VAEAERLLAP----------FLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCISVQEEWKQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLK----------AAILSMLPEEDVVATNENVVTLFRQVDSLKQR-IAGKSIPTEKFAVRKARRYSASLP-------APVKLILPALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAELCYNHVVE-----------SEKLLKYDHYLVPFTLFELASLYKSQG--EID-KAIKFLETARNNYKDYSLESRLHFRIQAALHLWRKPSSD-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7N7-1", "uniprot_id": "D4A7N7_RAT", "id": "D4A7N7-1", "name": "", "aln": "----------------------------------------------------------------------MSRYQRHEDNDEYLLNTLSLSEGETERMARVTR---SVNLRDSETEDKFEDAHEIIPVATTMSLLSSLEECTTGLYLFLNNRFSDAINLIHPWSKNSSYHALIYSMFMVVKAILTFEP-----QDIQIGMNAAKEALKTCNN--FRKKPR-IMTLSRLVSRQGIKSIKEEELHAEVCYAECLVLKSAITFIQ-----------------------------------DDSLLNFLKSGVNVGSSYQIYKDCQQVLELMPENQSK---------------------------THR--HLNGGIKFGVGVFNLMFSLVPPKSLKLLNMVGYSGDREVGLALLHDSASEPHINNILSVFTLLFYYN------------YVRVVVGVEKAS----TAATESLFLV----------YLEKFPNCVVLKFFRARFNMLNGNFESAKLKLQECIITQNEWKQVHHLCYWELMWCHIFLQNWKQAYNYANLLFQHSRWSKAIYTYSK----------AIILALLPPDSVDSENESLSSYFLRVDSLRIK-FLGSSVPIEKFIAEKSQRYGTTTG---------WFTAQPLLEFIYAWSGFRVMSKKIELISSWLMIIDKGKELLNENPNEEYGVDDMSLLNLLKGLCLKHLGKHLKAEHYFIRVIR-----------KERSLKYDHYLVPYSYYELGMLHYLKG--DYT-NATKNLDNIKN-YKDYSMEARLQFRAHIALEQIAKLEK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36114-1", "uniprot_id": "YKR18_YEAST", "id": "P36114-1", "name": "IML2-like protein YKR018C", "aln": "----------------------------MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLDDNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEALSLKSRERAQKIGLKSSSLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRKSYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQKDKDLLQFAEQIHSMRTERLSG-------------------------AHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLSDDIDLS-------------------------QATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWKATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLHPGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKSLMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMKSDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPLDGIATSPVHEIAYFYNGYNRMSEEH------LELTKKMLTEYRNPAIEALDSDQELIKDLLVSLTLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLEGMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :*::.: :.: . . : : : : : :: . ::. : .. ....:.: * ::: :*:.*. ::.. *: *.: *: : .: .. : : :: :: . . :: :*. : : .* : . : * : ::.: : :: : : * . . **:. * : . * * : .. ::* .: .: *. * :.. . : : : ** . : . . . : : * : * . . .. * : *.:. * .: : * ", "identical_positions": 27, "similar_positions": 124, "identity": "3.28%" }, { "cls_id": "homologset.agr.SGD:S000001727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54916-1", "uniprot_id": "REPS1_MOUSE", "id": "O54916-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "------------MEG------------LTLSDAEQKYYSDLFSYCDIESTKKV----------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLR------------------------------------------------------------------------VESINTVKDLPLPRFVASK-----------------------------------------------------------NEQESRLAASYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQP-RPSAEQQ-------------------EPVSPVVSPQQSPPTSPHTWRKHSRHPS-----------------------------GGNSERPLTGPGPFWSPFGDAQAGSSAGDAVWSGQSPPPPQDN----------WVSFADTPPTSALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYEDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEF-FTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGEQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIR-------------------------------MTPSKIHMQEMELKRTSSDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNTV-DGYSSSD---------------------------------------------------------------------------------------------------------------SFPSDPEQIGSSVTRQRSHSGTSPD------------------------------------------------NTAPPPPPP-----------------------------------------------------------------------------------------------RPQPSHSRSSSLDMNRTFAVT-------------------------------------------------------------------------------------------------TGQQQAGVVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRAAQADSKAEEKTATNVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTG-VLAAVLTSQPSIPRSVGKDKKAIQASIRRNKETN-----------TVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LDV5-1", "uniprot_id": "A0ABK0LDV5_RAT", "id": "A0ABK0LDV5-1", "name": "", "aln": "------------MEG------------LTLSDAEQKYYSDLFSYCDIESTKKV----------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLR------------------------------------------------------------------------VESINTVKDLPLPRFVASK-----------------------------------------------------------NEQESRHAASYSSDAENQSAYAGVIPPPPGRGQVKKAPGSHDAAQP-RPSADQQ-------------------EPASPVVSPQQSPPTSPHTWRKHNRHPS-----------------------------GGNSERPLAGPGPFWSPFGDAQSGSSAGDAVWSGHSPPPPQEN----------WVSFADTPPTSALLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEF-FTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYPGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIR-------------------------------MTPSKIHMQEMELKRSSGDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNTVADGYSSSD---------------------------------------------------------------------------------------------------------------SFPSDPEQIGSNGARQRSHSGASPD------------------------------------------------NTAPPPPPP-----------------------------------------------------------------------------------------------RPQPSHSRSSSLDMNRTFAVA-------------------------------------------------------------------------------------------------TGQQQAGVVTHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRVAQADSKIEEKTAAGVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETN-----------TVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96D71-1", "uniprot_id": "REPS1_HUMAN", "id": "Q96D71-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "------------MEG------------LTLSDAEQKYYSDLFSYCDIESTKKV----------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLR------------------------------------------------------------------------VESINTVKDLPLPRFVASK-----------------------------------------------------------NEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQP-RTSADAQ-------------------EPASPVVSPQQSPPTSPHTWRKHSRHPS-----------------------------GGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQEN----------WVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEF-FTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIR-------------------------------MTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSD---------------------------------------------------------------------------------------------------------------SFTSDPEQIGSNVTRQRSHSGTSPD------------------------------------------------NTAPPPPPP-----------------------------------------------------------------------------------------------RPQPSHSRSSSLDMNRTFTVT-------------------------------------------------------------------------------------------------TGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETN-----------TVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7S1-1", "uniprot_id": "A0A8M2B7S1_DANRE", "id": "A0A8M2B7S1-1", "name": "", "aln": "------------MES------------LTLSDVEQKYYSELFLSCDVDNAKKV----------------ASNGKVLELFRAAQLSNEVVLQITELCGATRLGHFGRSQFYIALKLIALAQSGLPLR------------------------------------------------------------------------LESLNTVRDLPLPRFVMGK-----------------------------------------------------------NEQETRHMVMFT-DAENQG---PFLPRPPGRVQAKKVS-AHEMIQPCVPTADPQP------------------DTTSPVVSPHQSPPTSPLAWRKHKRQAS-----------------------------GGNVDRQPSVPGVVWPHFREAQPGPVPGDGMWSAHSPPPVQES----------WVSFTDTPPSSTLPMHPPSAQTESSTVRTVPSAMTTNEIQRQTSGYDDPWKITDEQRQYYINQFKTIQADLTGLIPGSAAKEF-FTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLDDSAGVPEPAPEVGFSASPVEVTPNKSPSMPSLNQNWPELNQSNEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIR-------------------------------MTPSKIHMQEMELKRTGSDHTHPTSPLMTKPPELSDETKLAAAIKFP-GTAVGDGYSSSD---------------------------------------------------------------------------------------------------------------SFTSDQEPISSAVNRQRSHSGTSPEG-------------------------------------------LK--VVAPPPPPP-----------------------------------------------------------------------------------------------RPHASHSRSSSLDMNRNFAAVP-----------------------------------------------------------------------------------------------AAGSQQAGVVAFPPAVPPRPLPTQTSVPHGHRSVEGDGLPAHTSTSPQQMPEQPNFADFSQFKAFAVDQPADDGENPSDGG----QAERLPEAAGTMRTAKNDVQAEERNATTVNS--AKVSTPLAPPPKPVRRRLKSEDELRPDVDDLPQKSN-VIATVLATQPSIPRSLGKDKKAIQASIRRNKETN-----------TVLARLNSELQQQLKDLLEERISLEVQLEQLRPFSHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q80XA6-1", "uniprot_id": "REPS2_MOUSE", "id": "Q80XA6-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "------------MEVAAGGGCGAG-PPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEATRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAGLPVR------------------------------------------------------------------------TESIK--CELPLPRFVMSK-----------------------------------------------------------NDGEIRFGN--------PAELHGPKVQIP------YLTTEKNSFKRMDN-EDKQ-------------------ETQSPTMSPLASPPSSPPHYQRVS-------------------------------------------LSHGYSKLRSGTEQMHPAPYE--RQPIGQPEG---------------PSSEGPGAKPFRRQASLIRSFSVEREP-------QENNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNF-FTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYPLPEGLPPTLQP----EYLQAAFPK-----------------------------------------------SKWECAIFDS----------YSESMPAN-------------------------------QQSCDLNRMEKTSVKDVADFPVPTQDVTTADDKQALKSTVN--------ESLPKDVSEDT---------------------------------------------------------------------------------------------------------------ATSKDYNSLKARP-RSRSYSSTSIEE-------------------------------------------AMKRGEDPPTPPP-----------------------------------------------------------------------------------------------RPQKTHSRASSLDLNKVFLPS-------------------------------------------------------------------------------------------------APAANSGLLPPPPALPPRPCPTQ----------------------SEPVSEADLHSQLN----------------------------RAPSQAAESSPTKMDAPHAQP------------------PSKPIRRKFRPENQTTESQEPAAAVGGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEAN-----------AVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AED1-1", "uniprot_id": "A0A8I6AED1_RAT", "id": "A0A8I6AED1-1", "name": "", "aln": "------------MEVAAGGGGGAG-PPLLLSDSEQQCYSELFARCAGAASGGPGPGPLEATRVAPGILTAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAGLPVR------------------------------------------------------------------------TESIK--CELPLPRFVMSK-----------------------------------------------------------NDAEMRVGN--------PAELHGTKVQIP------YLTSEKNSFKRLDD-EEKQQ------------------ETPSPRMSPLASPPSSPPHYQRVP-------------------------------------------LSHGYSKLRSGTEQMHPAPYES-RQPIGQPEG---------------PSSEGPGTKPFRRQASLIRSFSVEREL-------QENNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNF-FTKSKLSIAELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP----EYLQAAFPK-----------------------------------------------SKWECVIFDS----------YSESMPAN-------------------------------QQSCDLNRMEKTSVKDMADFPVSTQDVTTGDDKQALKSTVN--------ESLPKDVSEDT---------------------------------------------------------------------------------------------------------------ATSKDCNSLKARP-RSRSYSSTSIEE-------------------------------------------AMKRGEDPPTPPP-----------------------------------------------------------------------------------------------RPQKTHSRASSLDLNKVFQPS-------------------------------------------------------------------------------------------------VSAANSGLLPPPPALPPRPCPTQ----------------------AEPASEADLYPQMN----------------------------RAPSQAAESSPTKKDVPHAQP------------------PSKPIRRKFRPENQTTEGQESAAVVGGAAPAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEAN-----------AVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NFH8-1", "uniprot_id": "REPS2_HUMAN", "id": "Q8NFH8-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVR------------------------------------------------------------------------IESIK--CELPLPRFMMSK-----------------------------------------------------------NDGEIRFGN--------PAELHGTKVQIP------YLTTEKNSFKRMDD-EDKQQ------------------ETQSPTMSPLASPPSSPPHYQRVP-------------------------------------------LSHGYSKLRSSAEQMHPAPYEA-RQPLVQPEG---------------SSSGGPGTKPLRHQASLIRSFSVEREL-------QDN-SSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNF-FTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP----EYLQAAFPK-----------------------------------------------PKWDCQLFDS----------YSESLPAN-------------------------------QQPRDLNRMEKTSVKDMADLPVPNQDVTS-DDKQALKSTIN--------EALPKDVSEDP---------------------------------------------------------------------------------------------------------------ATPKDSNSLKARP-RSRSYSSTSIEE-------------------------------------------AMKRGEDPPTPPP-----------------------------------------------------------------------------------------------RPQKTHSRASSLDLNKVFQPS-------------------------------------------------------------------------------------------------VPATKSGLLPPPPALPPRPCPSQ----------------------SEQVSEAELLPQLS----------------------------RAPSQAAESSPAKKDVLYSQP------------------PSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEAN-----------AVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9B6-1", "uniprot_id": "A0A8M2B9B6_DANRE", "id": "A0A8M2B9B6-1", "name": "", "aln": "------------MDPGSAGG-----TFMSLSDTEQRCYSGLYALCQPDSSGIP-----------------AAGKVAELFRASQLPAETLHQVMEVCGAKRLGFFGCGQFYAALKLLAAAQAGLPVR------------------------------------------------------------------------LESIA--GELPLPVFVGIT-----------------------------------------------------------NELDTRYANHLSTSESQPHTLGSVPASAP------RPPTDRAVLRHPDTSMDKQE------------------AWSPPRSPPSISPPRSPSAYR-----------------------------------------------SLTYSAQRNGTDTLLAYDGKMPGRPSVPQEN---------------ASPGHYSFKLQPEQPSITRVASVERLV-------ERVEVDYSDDPWRITEEQREYYTNQFRSLQPDLNALIMGAVAKNF-FTKSKLPIPELSHIWELSDVDKDGALTFPEFCTAFHLIVARKNGYLLPETLPASLRPGFQEPVVTAAPSE-----------------------------------------------ATQPLIVFDDNM--------MPGANQLE-------------------------------IGSVDLQVTSRPGVTTKQDTRDESRKPEISPKRVPEPHEKP--------MQRVSALKPDS---------------------------------------------------------------------------------------------------------------PQELDAN-MKSRT-RPRSYSSTSIDD-------------------------------------------AMKKVEEPPTPPP-----------------------------------------------------------------------------------------------RPQKSHSRASSLDLNKLLQQG-------------------------------------------------------------------------------------------------TPGAKSGWLPPPPALPPRPPATQIF-----------SFLPGLEKSSQKAVQQPNFADFSRFREEQESGV------------------RAGLSTEDLLPPKSDCSLVHQGHA---------------PQKPMRRKLHPESQSATPPLTTPYS----AATLTKPT---QRPPPKQKREIQMAIRKNRETN-----------AVLTRLNSELQQQLKVVHGERLTLETQLESMRPVAST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NZM3-1", "uniprot_id": "ITSN2_HUMAN", "id": "Q9NZM3-1", "name": "Intersectin-2", "aln": "------------MMAQFPTAMNGGPNMWAITSEERTKHDRQFDNLKP-SGGYIT-----------------GDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS-LSSATSGTNLPPLMMPTPLVP-SVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLG-----SSSS-TSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDS-----ING--TLPSYQKMQEEE-------PQK-KLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQ-EEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSG-VSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKK-KLEDEAARKAKQGKENLWKENLRKEE-----------EEKQK----RLQEEKTQEKIQEEERKAEEKQRK---------------DKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVD-----EKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKAL------------------LPPTVSLSATSTSSEPLSSNQ------------PASVTDYQNVSFS----------------------NLTVNTS---WQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGRGWFPKSYVKIIP-----GSEVKREEPEALYAAVNKKPTSAAYSVGEE--------------YIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLG--PSSERATPAFH---------PVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQTLDTMQPIERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLFSSKSNAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQESKGPMTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AMD2-1", "uniprot_id": "A0A8I6AMD2_RAT", "id": "A0A8I6AMD2-1", "name": "", "aln": "------------MMAQFPTAMNGGPNMWAITSEERTKHDKQFDNLKP-SGGYIT-----------------GDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIHQPLPPVAPITAPLSSATSGTSIPPLMMPAPLVP-SVSTSSLPNGTASLIQPLSIPYSSSTLPHASSYSLMMGGFGGASIQKAQSLIDLG-----SSSS-TSSTASLSGNSPKTGTSEWAVPQPSRLKYRQKFNSLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDS-----ING--TLPSYQKTQEEE-------PQK-KLPVTFEDKRKANYERGNMELEKRRQVLMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERIRRQELLNQKNREQ-EEIVRLNSKKKSLHLELEAVNGKHQQISGRLQDVRIRKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSG-ISLLHKKSSEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLK---------------------------ELRESYNTQQLALEQLHKIKRDKLKELERKRLEQIQKK-KLEDEAARKAKQGKENLWKESIRKEE-----------EEKQK----RLQEEKSQDRTQEEERKTEAKQS----------------------------ETARALVNYRALYPFEARNHDEMSFNSGDIIQVD-----EKTVGEPGWLYGSFQGKFGWFPCNYVEKMLSS--DKTPSPKKAL------------------LPPAVSLSATSAAPQPLCSNQ------------PAPVTDYQNVSFS----------------------NLNVNTT---WQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKIIP-----GSEVKRGEPEALYAAVNKKPTSTAYPVGEE--------------YIALYSYSSVEPGDLTFTEGEELLVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENVGNASKSGASNKKPEIAQVTSAYAASGAEQLSLAPGQLILILKKNSSGWWQGELQARGKKRQKGWFPASHVKLLG--PSAERTTPAFH---------AVCQVIAMYDYIANNEDELNFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQPMERKRQGYIHELIETEERYMDDLQLVIEVFQKRMAESGFLTEAEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVEMMGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDADFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQNHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLYSGKLYKTKSNKELHGFLFNDFLLLTYLVRQFAASSGFEKLFSSKSSAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESKGPTTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PBV5-1", "uniprot_id": "A0A8M9PBV5_DANRE", "id": "A0A8M9PBV5-1", "name": "", "aln": "--------------------MNGGFSIWAITPEERGKHDKQFDSLAP-TLGYLS-----------------GDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLPIIMKQTPTPVMTSSSRFGMGSMPNLSAMSVMPILTPIPTCPVMAPLVPVPTLISGPLPQMPNSISVPALPNGNATLLTPTPAFPVSS------------------GLTKSHSLLDLG-----SSSSNSSSTTSLASNSPKTSSSDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTGRPLPLTLPPDLVPPSLRTTKSCDL-----LNGPVPLISTELIEPEL-------PQKNKSNVSYEDKLRENFQRGNAELEKRRLALQEQQRREEERRREEERREEEKRQQKEREERERREREAREMEIRRQREEERRMERQRELERQREEERLKELERR----EEAERQRRREWEKSKRVELQTQKEKEQ-NDIQRLKDRKRSLEIELEAVGNKHKQISSQLRDAKSKRQGQWAELELINQRRDVCITDINSLQLQFDEMQRQLNQLGPEKQRLADRLVHFTQN-ISSPL-INDVKQSVCEKDRSCRKLKEQLDVLERETTAKLSQMEQYNKEIKFVEMDDCVLQGLLSLLGCLTNLFLLIKELRQKQSQQQDVLEQLRRVRSDKLKELQRHRKEEEERKRKKEEEAARQAQLEQERLEQEEAERQRKLAQEREAKLREEQQRQALARLLEAQEQARAKEEKRRAEEKERNELDVHTQSSLPFNSTENNILQPVVIPEVTCSSLTTYRALYPFTARNSDELTLEADCFIQVD-----ESTVRETGWLYGSYSGNRGWFPESYAERCSKD-------------------------------SQTQPTAAETESTAPSANYP------------GIPRVDIEGPTPT----------------------HTPVSTN---TQHS-------------------------QAVALCEWSAKTDSHLGFCKDDIITVLEKQENWWYGELKEKRGWFPCSHVSVVT-----TNNTQ---SEPLYSSVEEIEVSDS-GLLDE--------------YVALYTYESPESGDLTFSAEDVVLVTEKEGEWWRGCIGDQTGLFPSNYVKPKEPDTASSAVPS----KKPEIAQVTTVSPATTPEQLSLTPGQLIVVLHKNSNSWWLGELQARGKKRKKGWFQSSNVRLLE--ANSGKITPAPQ---------PLCQVIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGEVAGVTGLFPTNYVKMTTECDPSQQWCADLLSLDSMCTEERKRQGYIHELIQTEESYLEDLELAVEVFYKPMAESGRLTEAEISMIFVNWRELIMCSTKLLKALRVRKKTAGERMPVQVVGDILSSELSHMQAYIRFCSCQLNAAALLQQKTDKSLDFKLFLKKIASNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPPAHADHSNLQAALEQAEELCSQVNEAVREKENSDRLEWIQNHVLCDGVIEHLVFNSLTNCLGPRKLLHSGKLHKTKSSKELWALLFNDFLLLTYTSKQFSSSP--DKLFNPNSNTQYKMYKTPVFLNEVLVKMPSDPSSDDPVFHISHIDRVYTLKTDTINERTTWVQKIKAASDHFIETEKLKREKAYQARSQKNSGIGRLLVTVLEATELKPCKPNGKSNPYCELTMGAQCYTSRHQPDTLNPKWSFNCQFFIKDLYQDVLCLTVFERDQFSPDDFLGRTEVPVATIKKDQDGKGPLVRRLLLHEVPTGEVKVRLDLQLYEQTPHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q15811-1", "uniprot_id": "ITSN1_HUMAN", "id": "Q15811-1", "name": "Intersectin-1", "aln": "-------------MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKP-ISGFIT-----------------GDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISS-APAFGMGGIASMPPLTAVAPVPMG----SIPVVGMSPTLVSSVP-----TAAVPPLANGAPPVIQPLPAFAHPA-----------------ATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPV---AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSG-----ISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQ-EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDS-LVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLK---------------------------ELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEE-----EKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWS---TAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAP---------------APKLALRETPAPLAVTSSEP---------STTPNNWADFSSTWPT-STNEKPETDNWDAWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGE-------------EFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS--PGTSKITPTEP--PKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSG-TDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVE9-3", "uniprot_id": "ITSN1_RAT", "id": "Q9WVE9-3", "name": "Intersectin-1", "aln": "-------------MAQFPTPFGGSLDIWAITVEERAKHDQQFQSLKP-ISGFIT-----------------GDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALPPVMKQQPAAISS-APAFGIGGMAGMPPLTAVAPVPMG----SIPVVGMSPPLVSSVP-----QAAVPPLANGAPPVIQPLPAFAHPA-----------------ATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPAA---AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSG-----MSVISSSSADQRLPEEPSSEDEQQ-VEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQ-EGIVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDS-LLTLKRALEAKELARQQLREQLDEVEKETRSKLQEIDVFNNQLK---------------------------ELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQERDKQWQEHVQQE-EQQRPRKPHEE-----DKLKREDSVKKKEAEERAKPEVQDKQSRLFHPHQEPAKP-AQAPWP---TTEKGPLTISAQESAKVVYYRALYPFESRSHDEITIQPGDIVMVD-----ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEIPTPAKPVTDLTSAP---------------APKLALRETPAPLPVTSSEP---------STTPNNWADFSSTWPS-STNEKPETDNWDTWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGE-------------EFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGTVGETSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS--PGTSKITPTEL--PKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSS-TDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BIP7-1", "uniprot_id": "A0A8M2BIP7_DANRE", "id": "A0A8M2BIP7-1", "name": "Intersectin-1", "aln": "-------------MAQFPTPFGGGSDTWVISVDERAKHDQQFHSLTPTPAGFIT-----------------GDQARNFFLQSGLPAPILAQIWALADMNNDGKMDMHEFSIAMKLIKLKLQGHPLPPSLPPSMKQQPISIPP-PTPFGIPSMGAMPGLPAVPPMPLPPLPPGVPGMGVSPPLGASV------TPPVPSLANGAPAMIQPLSGFSHPG-----------------AVLNKTPSFNRS------SIKLQKGQSVEAPSAPAAPPPADWAVSQSSRLKYRQLFNSHDKMMSGYLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSGLPLPPLLPPDLIPPTFRRMRSGSG-----VSVTSMHSTDLRSQEEP--EEEEKEAEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAALEKEEQERKERERLEQERRRQQELDKQLERQRELERQREEERRKEIERREAAKRELERQRQLEWERTRRQELLTQRNREQ-ENIVLLKARKKTLEFELEALNDKKSQLEGKLQDIRSRLSIQRHEIETTNKTRELRIAEITSLQQQLQESQQWLSRLIPDKQCLNDQLKQVQQNSLHRDS-LNSLQRAIEMKESTKQQLKEQLDAVEKETRSKLLEIDAFNTQLK---------------------------ELREIHNKQQRQKQKELEAD-ITQPSHDRKSIDSQDS------RLSGTDDGVSPAWRDDGLGKAPTPPVSQ-----AWMSRVS-----EEENHSRAEIQDNLSKLFTQHPQAGKIQAQSPWS---MADKIPVSGFNQEKVKVVYYRAMYPFEARSHDEITIHPGDIVMVKGEWVDESQTGEPGWLGGEIKGKTGWFPANYAEKIPESEVPLSLRASAASSSAPKLGSHMSSASSSTTATPILPVSTEPASIAPPSSAPPPTGPASSSSSASSNWADFSTTWPSNSAVEKQDSDGWDAWPTQPTQPSLSVPSGGQIRQRSAFTPATLSGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQRGWFPKSYVKLISGPVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEYVAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSGKIGVFPSNYVKPKESEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS--PSTSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLSREDPDWWKGELNGSVGLFPSNYVKLTTDTDPSQQWCADLHLLDMLTPVERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELTMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPEFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRLALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSG-TDKVFSAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKRKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSNGKSNPYCEVTMGSQCHVTKTLQDTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQGSKGPITKRLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND00-1", "uniprot_id": "M9ND00_DROME", "id": "M9ND00-1", "name": "", "aln": "--------------------MNSAVDAWAVTPRERLKYQEQFRALQP-QAGFVT-----------------GAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLLSS-----------LTGDVPSMTPRGSTSSLSPLDPLKGIVPAVAPVVPVVAPP----VAVATVISPPGVSVPSGPTPPTSNPP--------------------------------------SRHTSISERAPSIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKIKSRPGSVSGVVSRPGSQPASRHASVSSQSGVGVVDADPTAGLPGQNKRKENYVKGQAELDRRRKIMEDQQRKEREE-----------RERKEREEADKREKARLEAERKQQEELERQLQRQREIEMEKEEQRKRELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQ-ERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMS--------------------------------ELKAELSALITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVT-----------------------DPYAVASNDISALAAPAVDLG--------------------------GPAPEGFVKYQAVYEFNARNAEEITFVPGDIILVP-----LEQNAEPGWLAGEINGHTGWFPESYVEKLEVG-----------------------------EVAPVAAVEAPVDAQVATVADT------------YNDNINTSSIPAA----------------------SADLTAAG----------------------------DVEYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTIGSRTGMFPSNYVQKADVGTASTAAAEPVESLDQETTLNGNAAYTAAPVEAQEQ-----------VYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSEPAESYSR-PMSRTSSMTPGMRAKRSEIAQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYVKVLQGGRNSGRNTPVSGS-RIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGELNGLSGLFPSNYVGPFVTSEIKP----------DPGACSRRSKGIQRLWQQWRGCDIDQAAQHGDASNNKLRG-------------------------IIQAVHITKRRDGQLMG---------------CAYVRFECNELLAKSMLQENGNQLVGKAVVVDWQPELPKKRFRQWRCW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36115-1", "uniprot_id": "IRS4_YEAST", "id": "P36115-1", "name": "Increased rDNA silencing protein 4", "aln": "---------------------------MRLSFGKQRYHGGTTVTLTEQGASDSLR----------------AAQAIFQNHSNEVSSPCPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIRTKQVP------------------------------------------------------------------------------KIKTTAPNDVELS--------------------------------------------------------------------------------KKHRSSPAGKDNVSSTAQMAAALAHSQSKLSSDN-------------------NSSHSSALDTLKVLETPNLNGLLGIHS------------------------------------------RSSSRNGSNESLTPGQRTPDNRSQENLLT-----------------SFSSGRRLSSSSMEPATNKDSNKALPKRRPSPPLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTSLSQTINQLSLCESEPSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMDAS----------------------------------------------SEELGQHEQ---------------------------------------------------QPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYDDTDSDSESDQN---------------------------------------------------------------------------------------------------------------QDALTKPRKRDRIKRKIRNSANKTAH--------------------------------------------HRPIHRTRDR-------------------------------------------------------------------------------------------------KFNEDKPWKSHTDITFVTDNE-------------------------------------------------------------------------------------------------RKRYESMWVSN---------------------------------RHRHLNLLSWWPSITGDS------------------------GAINTLPEDGLILGIIVRDIWK-----------------RSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWDSVDRYASTT---------VVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: : . :. . . : : : . . . : . . . . : . : : : . . . : . . . . . . :: . . : . :: ", "identical_positions": 0, "similar_positions": 44, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000001729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPW1-1", "uniprot_id": "D3ZPW1_RAT", "id": "D3ZPW1-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------------------------MLFDKVKAFVVELDGTRAGTEPVFHGGQ------AVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA--------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------------------------------------------------------------------------------------------------------------IVMLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT--RGLVSLSAKIDRKGYTP------------GEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------CAVVASVDGEPVGPGRRALWPGR------------ALRIPPVG-PSILHCRVLSVDYSLKVCVDIPGSS-------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL-------------------------------------------------------------------------------CALMERPEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTE-----------------------------------------GPYFACLQEFRYRPPPLYS----------------EEDPNP-PSEAARPRCMTC--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D668-1", "uniprot_id": "ARRD2_MOUSE", "id": "Q9D668-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------------------------MLFDKVKAFVVEIDGARTGTEPVFHGGQ------AVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA--------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------------------------------------------------------------------------------------------------------------IATLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARCARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT--RGLVSLSAKIDRKGYTP------------GEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------RAVVASVDGEPVGPNRRALWPGR------------ALRIPPVG-PSILQCRVLSVDYSLKVFVDIPGSS-------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL-------------------------------------------------------------------------------CTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDLGVTTE-----------------------------------------GPYFACLQEFRYCPPPLYS----------------EEDPNP-PSEAVRPRCMTC--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBH0-1", "uniprot_id": "ARRD2_HUMAN", "id": "Q8TBH0-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------------------------MLFDKVKAFSVQLDGATAGVEPVFSGGQ------AVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSA--------------------------GSST-AYTQSYSERVEVVSHRATLLAPDTGE---------------------------------------------------------------------------------------------------------------TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-APQAGAREKVARSWYCN--RGLVSLSAKIDRKGYTP------------GEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQK------RAVVASLAGEPVGPGQRALWQGR------------ALRIPPVG-PSILHCRVLHVDYALKVCVDIPGTS-------KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRL-------------------------------------------------------------------------------GALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLE-----------------------------------------GPFFAYIQEFRYRPPPLYS----------------EEDPNP-LLGDMRPRCMTC--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPQ9-1", "uniprot_id": "ARRD3_MOUSE", "id": "Q7TPQ9-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGD------TVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA--------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---------------------------------------------------------------------------------------------------------GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT--SGPISLSAKIERKGYTP------------GESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM-------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMSMNWLA-------------------------------------------------------------------------------LALPERPEAPPSYAEVVTE-EQRRNNLAPVGACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TXF1-1", "uniprot_id": "ARRD3_RAT", "id": "Q6TXF1-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGD------TVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA--------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNCEE---------------------------------------------------------------------------------------------------------GFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT--SGPISLSAKIERKGYTP------------GESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWDGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM-------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLG-------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96B67-1", "uniprot_id": "ARRD3_HUMAN", "id": "Q96B67-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGD------TVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA--------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---------------------------------------------------------------------------------------------------------GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT--SGPISLSAKIERKGYTP------------GESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM-------DLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLS-------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSADDRPSCPSR--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F4-1", "uniprot_id": "ARRD4_MOUSE", "id": "A0A0B4J1F4-1", "name": "Arrestin domain-containing protein 4", "aln": "------------------MGGEAG---ADGPRGRVKSLGLVFEDESKG---CYSSGE------TVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGA--------------------------RVCIGGGSPAASSEVEYLNLRLSLLEAPAGEG--------------------------------------------------------------------------------------------------------------VTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVLERP-QVPDQSVRRELQVVSHVDVN-TPPLL-TPMLKTQEKMVGCWLFT--SGPVSLSVKIERKGYCN------------GEAIPIYAEIENCSSRLVVPKAAIFQTQTYLASGKTKTV------RHMVANVRGNHIGSGSTDTWNGK------------MLKIPPVT-PSILDCCIIRVDYSLAVYIHIPGAK-------RLMLELPLVIGTIPYSGFGRRNSSVASQFSMDMCWLA-------------------------------------------------------------------------------LALPEQPEAPPNYADVVSE-EEFSRHVPPYPQPSDCDGEAC-----------------------------------------YSMFACIQEFRFQPPPLYS----------------EVDPHPGDAQETQPVSFIL--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCT1-1", "uniprot_id": "ARRD4_HUMAN", "id": "Q8NCT1-1", "name": "Arrestin domain-containing protein 4", "aln": "------------------MGGEAGCAAAVGAEGRVKSLGLVFEDERKG---CYSSGE------TVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCP--------------------------RASASTAALAVFSEVEYLNVRLSLREPPAGEG--------------------------------------------------------------------------------------------------------------IILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERP-KVPDQSVKRELQVVSHVDVN-TPALL-TPVLKTQEKMVGCWFFT--SGPVSLSAKIERKGYCN------------GEAIPIYAEIENCSSRLIVPKAAIFQTQTYLASGKTKTI------RHMVANVRGNHIASGSTDTWNGK------------TLKIPPVT-PSILDCCIIRVDYSLAVYIHIPGAK-------KLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLT-------------------------------------------------------------------------------LTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVC-----------------------------------------CPVFACIQEFRFQPPPLYS----------------EVDPHPSDVEESQPVSFIL--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "----------------------------MVMFKKIKSFEVVFND----PEKVYGSGE------KVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG------------------------------------SQQCKQTLDYLRYEDTLLLEEQPTAGENE---------------------------------------------------------------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP--DGRVSVSARIDRKGFCE------------GDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVF------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILKVEYSLLIYVSVPGSK-------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID-------------------------------------------------------------------------------LNIPDTPEAPPCYMDIIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNNNNVQ----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "----------------------------MVMFKKIKSFEVVFND----PEKVYGSGE------KVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQG------------------------------------SQQCKQTLDYLRYEDTLLLEDQPT-GENE---------------------------------------------------------------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP--DGRVSVSARIDRKGFCE------------GDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILRVEYSLLIYVSVPGSK-------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID-------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNN--VQ----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "----------------------------MVMFKKIKSFEVVFND----PEKVYGSGE------KVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG------------------------------------SQQCKQTSEYLRYEDTLLLEDQPT-GENE---------------------------------------------------------------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQETKKNFEVVDLVDVN-TPDLM-APVSAKKEKKVSCMFIP--DGRVSVSARIDRKGFCE------------GDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILRVEYSLLIYVSVPGSK-------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWVD-------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDMDGSQD-----------------------------------------SPIFMYAPEFKFMPPPTYT----------------EVDPCILNNNVQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KN1-1", "uniprot_id": "ARRD1_MOUSE", "id": "Q99KN1-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------------------------MGRVQLFEIRLSQ----GRVVYGPGE------PLAGTVHLRLGAPLPFRAIRVTCMGSCGVSTKAN------------------------------------DGAWVVEESYFNSSLSLADK--------------------------------------------------------------------------------------------------------------------GSLPAGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK--TGNVVLTASTDLRGYVV------------GQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRRAQWQEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSMKAP----------EATVTLPLFVGNIAVNQTPLSPCP---GRESSPG----------------------------------------------------------------------------------TLSLVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVT----TTEPWVQVGSPARHSLHP-PLCISIGATVPYFAEGSAGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNL6-1", "uniprot_id": "ARRD1_RAT", "id": "B0BNL6-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------------------------MGRVQLFEIRLSQ----GRVVYSPGE------PLAGAVHLRLGAPLPFRAIRVTCMGSCGVSNKAN------------------------------------DGAWVVEESYFNSSLSLADK--------------------------------------------------------------------------------------------------------------------GSLPPGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK--TGSVVLTASTDLRGYVV------------GQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRHAQWQEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSMKAP----------EATVTLPLFVGNIAVNQTPLSPCP---GPGSSPG----------------------------------------------------------------------------------LLSPVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSTTLGSVSVT----TIEPCVQVGSPARHSLHP-PLCISIGATVPYFAEGSGGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAGGTDVGLIPGS-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5I2-1", "uniprot_id": "ARRD1_HUMAN", "id": "Q8N5I2-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------------------------MGRVQLFEISLSH----GRVVYSPGE------PLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKAN------------------------------------DTAWVVEEGYFNSSLSLADK--------------------------------------------------------------------------------------------------------------------GSLPAGEHSFPFQFLLPAT-APTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASATKKFSYKLVK--TGSVVLTASTDLRGYVV------------GQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHD------VRTIAEVEGAGVKAWRRAQWHEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSLKAP----------EATVTLPVFIGNIAVNHAPVSPRP---GLGLPPG----------------------------------------------------------------------------------APPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG-----APEPCPQDGSPASHPLHP-PLCISTGATVPYFAEGSGGPVPTTS----------------TLILPPEYSSWGYPYEAPPSYEQSCG--GVEPSLTPES-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7Q5-1", "uniprot_id": "A0AB13A7Q5_DANRE", "id": "A0AB13A7Q5-1", "name": "", "aln": "-------------------------------MGKVQEFEITFTN----NKVVYNPGE------SISGTVRIKSSHSLQFKAIKVCCVGSCGISSKLN------------------------------------DASWMLEEKYLSSTLSVADK--------------------------------------------------------------------------------------------------------------------GTLPPGEHSFPFQFLIPAS-VPTSFEGPFGKILYKIRAFIDTPRFSKDYKAQRPFYLLNVLNLNELPDIE-QPSCAVTTKKFNYLLVK--TGTLMLKAYTDLRGYTP------------GQVIKLSAEIHNKSGKDTGYVMASLIQRVSYKTKRPVFD------LRPIAEVEGAGVKAGKHAEWREQ------------IIVPPLPQ-SGLTGCNLIDIEYFIQVSLKSP----------EAAVTLPIYIGNIAVNLTPSIPHPMAHGVPMPTGPSL-------------------------------------------------------------------------------NPAAVVPSAPPVEEELAGQLAAGG--GDSEEIPTKSHSQQDPSGAPLSVAPYGHASGPVLPQSQQHVQSTDGSAP-LFCLSTGATIPFFTDGNATPVPTSC----------------PLILPPEYSTWEYPHEPPPTYEESCSSNNSSFNSSMR--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT80-1", "uniprot_id": "A0AB32TT80_DANRE", "id": "A0AB32TT80-1", "name": "", "aln": "-------------------------------MGKLQEFEISFDN----NKTVYSPGE------SLTGTLKISIAQSIQCKAIKVNCQGFCGVTSKSN------------------------------------DTDWTDEEQYFSSSVSIADK--------------------------------------------------------------------------------------------------------------------GTLKEGEHSFPFKFLLPAA-APTSFVGPYGQIMYRVRAFIDTPRFAKDYKIEKPFSMTNTLNLNEVPGIR-EPSSSSVTKNFSYMLVK--NGTVVLNAKTDMRGYIA------------GQIIKVSAGIENKSDKTTGHVVASLMQKVTYNTKKQTYD------LRSVAEVEGPGVKGGNKSEWNQQ------------IIVPALPH-SSLSDGNLIQICYYIQVYLKYP----------EVALTLPICIGSVALDPSQPSHSQT--VAPMPAPR---------------------------------------------------------------------------------ITPAPSPSAPESEASNLPPRPAPKPAPKPRPRSTHASPSAPPVDLYPQLPSVSNYNGEMLKSPHQEPGSQGPVSPNAFSYAPGLSFRQRQSSSGPSAPPLS----------------LSSSSQDRNQMPSSASVPPSYRSSAYPQATNSEVLDESSSKNW--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------------MVICEIEFCNN---SQGIFYAGQ------LISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHD---------------------------PDDQSNGESFNGHVDYLATRAYLHGS------SSS---------------------------------------------------------------------------------------------------------IEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRP-WKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCR--SSPLSMRLSVPQSGFVP------------GQIVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSA-DTNKDRFEMVLKTGGGVSTKCRQQFTFD------------LKVPPTPP-TCFNLCSIIQIGYQVEAEARVKGCHG------GQSLHMPITIGSVPLT-KQLQKE--PRTWGEVLPPQQL----------------------------------------------------------------------------DAKALILIGSEQNGEALGSPNPWAADPSIAPPSYAEAKHISPDPHKFSKSKKKSQKRG------------VKGSQERKAETIVFSPLYAVFDLSNQVDEMT-------------------LRANEPKTDG-----GYVNEGVEKSTWL----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MGIICQILFHNN---TQGVFYAGQ------MVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTD---------------------------SNNKSTSESYNGFEKYLSSKVYLLGS------EIS---------------------------------------------------------------------------------------------------------PEMALEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQP-WKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFR--SDPLTLELNLPQTGFVP------------GQTVPANVLIGNES-KIRVHEVKVGLSMMITYYSDLSSG-SKCERKSVAKLKADG-VLRNSRKMYDFQ------------LMIPSTPP-SCFHLCRIIKIGYQIEVVAKVKGMHI------NGTLIMPVTICGVPISPSAVQYT--PQSSGPEAPEQ--------------------------------------------------------------------------------RALTLIEGEGAFAPAAPPYPWSEGSTLSPPNYAEAMHSHSDSEKQSESGNAQEKS--------------------------YKPLYPVFDLSTSTVEKS-------------------KEAALDKEE-------------KK--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MTVTCEIDFDNN---PHGTYFGGE------VLTGRVTLKLDKMKLVKAITLNITGYAETRWIERVT----------------------------TNRRRRRRTFCGREDYIASKTFLVGS------NLS---------------------------------------------------------------------------------------------------------SQVSIEAGIHTYNFVCLIPTE-CPSSFEGSHGRVRYMATVTLVRP-WKFDQSYTRCFTVLKVMDLNFDSPLLRVPAHSETSKTYCCWPCR--SDPLALQLTVPQTGFVP------------GQNVPLSVLVTNDS-HIPVEQLLISFVMLVTYHSKPPSMPNTTSERLVVNTFKGDAVQRNCKKLFSYE------------IRVPATPP-TCFNLCGIIQIAYQVEVEARVKGCHN------NEVVTIPLTIGSVPLA-QHVPIQ--PRGFVPQLNVN------------------------------------------------------------------------------------ELAVEEVATAPNSSSPWSVDASIPPPNYQEAVHMRSTAATRSDDLDDPEPVP------------PN---TLSLDGGAYKPLYPVFDIPSPSAPPP-------------------TDYTQNYMAERAFVNPAMDVDKDKGTWL----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MVVTCEISFDNN---KHGTFYAGQ------LVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLG---------------------------STKL-----YVGREDYLSSNTYLVGSEQNNTHNNT---------------------------------------------------------------------------------------------------------HRLTIEAGVHSYNFTCQLPYQ-CPSSFEGRHGCIRYIVKVLLIRP-WKFDQAYTKGFTVLKMLDLNFDTPQLKSAAHSEGYRTFCCGPCK--TDPLKLELHLPQAGYVP------------GQKIPVTIVVVNNT-AVAVSEIRLSLVMLVRYYSVSPEH--SRVERLIISRAKGESVLKQCTRSQTID------------LPVPSTPP-TCVELSNLIQIAYQLEVEALVKSLRE------QQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDS-----------------------------------------------------------------------------RRNPPDELPMVTALESLPSDLASSAADSALP-NYEESRHTQRGNINEEELHAFGSNE--------------------------FAPLYPVYSIPSPTPVLT-------------------ANARNAGFVN---------QSFVK--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MPSSCSFELDR----REPIYYSGE------TVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTR------------------------GGKTEHYTEYFRGKQQYLYTRTSVFGS--------------------------------------------------------------------------------------------------------------------GNLPPGTHTYNFCIPLPLE-CPSSVVAQYGKIFYEVSVVIDRQ-WRFNNVFKQPLTVIQTYNLN-MSPQLLMPLVREDIKHFCCWPCS--SGPVLSTLTIPFGGYAP------------GQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPHHKTREKEHSLNKSCQQERVLRLSKKKIEGT------------LAIPAVPPSSRTEG--IISVSYQVILTISTGDCHV------DSDFEVPIVIGTIPLIQS-----------------------------------------------------------------------------------------------------AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQ------------------DEHNRTDDFIPRYPMYTNFAMPSAPP------------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHZ9-1", "uniprot_id": "Q9VHZ9_DROME", "id": "Q9VHZ9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MPTTCVFQLDR----LNPVYNSGE------YISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMS------------------------------GKSE--TANYSGHQQYLHSRTNVFDN--------------------------------------------------------------------------------------------------------------------TLFRAGVHVYVLTLRIPPD-CPSTCKGPYGYIAYTISLTIDKP-WGFDEVFRKPIIVVQTLDLN-YNAEFSLPVKDENLKYLCHWPCI--SGPICSTLTLPASGFTP------------LQEVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKRN-FYSKTLVKELISDRTLRLSKRQYESS------------ICVPMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHY------DTDLSVPIIVGTTSLQHLRDSVHTQQPVRRTPTPERQRLIERV-----------------------------------------------------------------------TPRPPTVEEDSAGEADPATDEPHRVIEDDEPPSYDSCLPPSFSFATLAGSQQTLGSN------------------AAVVLQRIHLPKFPGFSTLIGTAPAHGMEDSGLDMHMYRSYGSLNTDHTGRSLDTFGSLCGPLSEHVEEQEQEAEENLDVTAQVHRPIQRATVSEVENVLQDEHLF-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------------------------MGLKGCELQLDN----PWNTYYAGQ------TVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTS-----------------------EGKTENEVTQLKGHEEYFKIQYYLLGGKNSS---------------------------------------------------------------------------------------------------------------ETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRP-WKFDQDMKMAFTVIAPVDLN-LNPRVKEPFKLELEKSFCCFCCR--SGPLAVITNIPQTGFVS------------GQVLPITCEVDNTS-NVNLTAVKFELRKLVTFHTNQPRS-EKRESKVIIANLSVGPVNGGESRTFTQQ------------MEIPALPP-TNLLNCGIIALDYDLHVECEVSGPHR------NLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS--------------------------------------------------------------------------------LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIP-----------------------------------------PPQFVETQYRAPTIAGRDD----------------SEHTQMIGDGAFAPRYPTFQFNNATAPPASQ--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MPIECLISFDNN---PQGVYYAGQ------ELSGVVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYP-----------------------------RDSERAMCRAYRSYLSSRSYVLGSCANN--------------------------------------------------------------------------------------------------------------SSIDWPAGEYSYTFHVILPDN-LPTSFDGKYGQIHYEIITTIERA-ARHPKVFKLPFTVIQPLDLN-ADAIYRVPLEILDRKRFWSFCCP--TGPLTVKFSTPYCGYAP------------GQKIHFVLYINNES-SIDIIECEVKLKQEVSYESHDPQHEYR-YDKHLIARKQFGNVLRWSRKVYRGY------------LDLPSIPP-TSVKPTCPISVNYSIKIIVNPTEFHW------KLKLKIPLTIGSIPIMDGPEALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQQRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDDTEFLTN----VSMSSILSAQADVTTSEPFKPRYPVYYDYETPTIPPET----------------LYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8K8-1", "uniprot_id": "Q0E8K8_DROME", "id": "Q0E8K8-1", "name": "", "aln": "------------------------------MPRKLLKFLIIFDN----TSLLYFPGQ------FLSGRVLIELQDETPALGLHFHVVGEGVVRNGRR------------------------------------QERTYDKENYIDFRMRLLGDVDQG--------------------------------------------------------------------------------------------------------------GPAILSPGIHSFPFKLGLPLG-LPSTFLGRYGWIQFYCKAALREN-NGIIHKNHQVFIVMNPIDLNLEKPILAQPFTCEVEHKLGVVCVG--GGQIKCRVSLDRGGYVP------------GENILVTAFISNYS-NVSIKRTKASLTETIEYLARGKVVQTE---KRELAVLVRGKIRPGAKDEWHNE------------LYVPPLPP-TNLHGCHLIKISYDVFFVIEPKSMEK------EIKLQLPIVLATYPFRHSGDAVN------------------------------------------------------------------------------------------------ANTWPESVLKPDTHTHYPSTLPIFRPWLHEKPIEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU7-1", "uniprot_id": "Q9VGU7_DROME", "id": "Q9VGU7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MSSKVNFVFDSN---PLGLYQAGQ------LISGTAELITERPKTIRSIFITINGYGETRWQESEERVGE-----------------------DGKTTKSLVTHTTTEVYYSTDQPVYGQAGGS---------------------------------------------------------------------------------------------------------------QLELPTGKYVFPFRATIPPN-APTSFNGAHGQIKHEVTLTIDRA-VRYNNTFKQCFTVILPHDLN-RRLEYKEPLQRLESKSFWWGSIFGAHKPMIMDVSTSYSAYVP------------GQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGEVLKHNKAKFDEF------------LTVPPTTP-STQSEKDPIRVSYTLRFIAKTFKLHGGG----DLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHPG----------------------------------------------------------------------------SPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATP------------------------VKFTPNPVSPAAQKSPPYTTNTP---------------VASPPGGNFEVLGFSIPPDYKPTPSAPAASSTGGIGWK-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "------------------------------MQRSIKELSVRYDPIN--ETNTFTNGD------IVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGD--------------------------DERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSGET------------------------------------------------------------------------------------------------------YGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRS--WKPTSSAQAEINFAPRNFG-TNDHLLQPQSGTEDKKMKLFGSG----KMSMTVTTDKTGYML------------GEIIRVSVDIDNSSSRDIKLKYSLKQLQTFIAGRSTTHA------HKDIVKETKDCIPSGGKTRFVVD------------IKLPHDIM-VTIENCRIIKVQYELKVYLDVSFAS-------DPTVKFPVVIIPPLQQCPPWHDPPPPYMPPQP---------------------------------------------------------------------------------------NLVPYPGGAAPPPAGLYPNLYDPVPPYPGTAAGTFPNP-----------------------------------------NAMLPGFHPAPSAPVYDLN-----------------QSTKESFPNAPH--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "--------------------------------MESERLRITLDS----ADRVYFAGD------IIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNS------------------------NNNEYSRSLFYTSKEVYEHSETPLPDFEPRG----------------------------------------------------------------------------------------------------------------LELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP-WTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR----PITLLALLPEDFAVR------------GEPLRICATVINNS-TTAVEKLRFTVLQYVTYYSHVPLR-VQKVECIAVATKETGSVQKKTERSFAHE------------LLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK------NLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGN-----------------------------------------------LFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTG----------GAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K7-1", "uniprot_id": "Q9I7K7_DROME", "id": "Q9I7K7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------------MSHRCEIQLDN----PRGVYRAGD------TVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKK--------------------NEQPVVVQSLDFDYRVDYFAKIDYFVGSEAAQP---------------------------------------------------------------------------------------------------------------QIMEAGTYNYGFHVKLPKN-CPGNFEGGHGHIRYTLQVLIHSSADRPLEVLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRLRFWMKP-----LHLQLQIPRQGYSP------------GAGISVHLKLHNPE-KLTLREAVYSLVQISTYVAHLKNK-----PKRLETKVERQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAATLTVAGCACLQLNYEVEVLVTTQQEKR------LIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEPTPP------------------------------------------------------------------------------------VETASTLIPNFSISTTSLASNFREAEFMVATNLNKT-----------------------------------------NKHYLSGEQLDFRPRYVYY----------------EMDQTQSEEVKSH--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36117-1", "uniprot_id": "ALY1_YEAST", "id": "P36117-1", "name": "Arrestin-related trafficking adapter 6", "aln": "MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAEPIVFLKGFETNGLSEIAPSILRGSLIVRVLKPNKLKSISITFKGISRTEWPEGIPPKREEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYIPPTAEPPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSSSRRGSVPANFHGNSLSPHTFISDLFTKTFSNSGATPSPEQEDNYLTPSKDSKEVFIFRPGDYIYTFEQPISQS-YPESIKANFGSVEYKLSIDIERFGAFKSTIHTQLPIKVVRLPSDGSVEETEAIAISKDWKDLLHYDVVIFSKEIVLNAFLPIDFHFAPLDKVTLHRIRIYLTESMEYTCNSNGNHEKARRLEPTKKFLLAEHNGPKLPHIPAGSNPLKAKNRGNILLDEKSGDLVNKDFQFEVFVP---SKFTNSIRLHPDTNYDKIKAHHWIKICLRLSKKYGDNRKHFEISIDSPIHILNQLCSHANTLLPSYESHFQYCDEDGNFAPAADQQNYASHHDSNIFFPKEVLSSPVLSPNVQKMNIRIPSDLPVVRNRAESVKKSKSDNTSKKNDQSSNVFASKQLVANIYKPNQIPRELTSPQALPLSPITSPILNYQPLSNSPPPDFDFDLAKRGAADSHAIPVDPPSYFDVLKADGIELPYYDTSSSKIPELKLNKSRETLASIEEDSFNGWSQIDDLSDEDDNDGDIASGFNFKLSTSAPSENVNSHTPILQSLNMSLDGRKKNRASLHATSVLPSTIRQNNQHFNDINQMLGSSDEDAFPKSQSLNFNKKLPILKINDNVIQSNSNSNNRVDNPEDTVDSSVDITAFYDPRMSSDSKFDWEVSKNHVDPAAYSVNVASENRVLDDFKKAFREKRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : * . : . * . : : : . . * : . : : . : : : *. : ", "identical_positions": 5, "similar_positions": 21, "identity": "0.54%" }, { "cls_id": "homologset.agr.SGD:S000001731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEP5-1", "uniprot_id": "B5DEP5_RAT", "id": "B5DEP5-1", "name": "Activating signal cointegrator 1", "aln": "MAVAGAASGEPLVHWCTQQLRKTFALDVS--EEIIQYVLSIES--AEEIRDYVTDLLQGNEGKKGQFIEDLITKWQKKDQECISDSFQQCWKKDESLDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVTVEVKTPLDLAKAQEGNSSVKKK------TRFVSLYTREGQDK-LAVLLPGR-HPCDCLGQKHKLIN---NCLVCGRIVCEQEGS--GPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAENSGKVDISTKDHPPHQESRMKSGLEKAVKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVERDMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIANGTLNQSLVTSDRSSEEPLGVLVNPNMYQAPPQWVDNTGSAPPKKTSLSVGPRLELSLHPHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVKGIKRVEGRSWYTPHRGRLWIAATGKRPSTQEVSELQATYRLLRGK-DVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXN3-1", "uniprot_id": "TRIP4_MOUSE", "id": "Q9QXN3-1", "name": "Activating signal cointegrator 1", "aln": "MAVAGAAYREPLVHWCTQQLQKTFALDVS--EEIIQYVLSIEN--AEEIREYVTDLLQGNEGKKGQFIEDLITKWQKNDQEFISDSFQQCLRKDEILDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVAVEVKTPLDLAKAQESNNSVKKK------TRFVNLYTREGQDK-LAVLLPGR-HPCDCLGQKHKLIN---NCLVCGRIVCEQEGS--GPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAETSGKVDVSTKDLLPHQESRMKSGLEKAIKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVEREMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIASGTLNQSLVTLDRSCEEPLGVLVNPNMYQASPQWVDNTGSTPQKKTSLSAGPRLEPSLHQHQLRIQDQEFQEGFDGGWCLSMHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATGKRPSPQEVSELQATYRLLRGK-DVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSSFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15650-1", "uniprot_id": "TRIP4_HUMAN", "id": "Q15650-1", "name": "Activating signal cointegrator 1", "aln": "MAVAGAVSGEPLVHWCTQQLRKTFGLDVS--EEIIQYVLSIES--AEEIREYVTDLLQGNEGKKGQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTEPDTTAEVKTPFDLAKAQENSNSVKKK------TKFVNLYTREGQDR-LAVLLPGR-HPCDCLGQKHKLIN---NCLICGRIVCEQEGS--GPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGK-DVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRA1-1", "uniprot_id": "Q9VRA1_DROME", "id": "Q9VRA1-1", "name": "ASCH domain-containing protein", "aln": "-----------MENFLRGTLSKCLDCVIT--DQMLAAILNIKD--DYEFDNYFGNLLSEDNEEHRMFLVNCRRMLLSG----------------------------KQPRNNGKYLSPPLAPTSP----------NCPKQNISKGAKGKS------GKHVNLYASDGRVQGDTIILKGR-RHCDCQAGQHKLIN---NCLGCGRIVCEQEGS--GPCLSCGDPVRTPEEE--------------QQLAKAAREKGGTKSAAKQGKKSTKELSTQALDKALAQRDRLLEYDKNSEKRTTVIDDELDYFQENS-VWLSDAEREKFEKLHREMEEVKHGSRMKRKIRVDFAGRELPEEPTISKEYEQQVISELAAVSKASGVGSNWSAS-SVTGHSALTLAPHLNMTKPPVYKPSKESKSWPAPAAGSDWLERTYN----RVQDKELLEMQDMRQCLSMHQPWASLLVAGIKKHEGRVWYSEHRGRLWIASTSKEPHAEDIAQMEGFYKVLYGDPDIKFPSHYPTSSLLGCVHVDSCLPQEEYRELYPNG--ESESPYVFVCTKPEQLNILLPVHGDHKIYELPLKTHTAACKTLLRARANKG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36119-1", "uniprot_id": "RQT4_YEAST", "id": "P36119-1", "name": "RQC trigger complex subunit RQT4", "aln": "------MTRKQAIDYAIKQVPQILPLEESDVKALCEQVLSTSSDDPEQIASKFLEFLG-HEDLSFEFVMKFNELLNQNDKKEEKKTKNVHLEHTAPTSWKNESKQPTNNYINKKGDEKPKKLKDEKKSSTTRPTVQPSNQSTQSNPIKEKKEHRSKGKLQSLQEIDEAIKMLELRDSGSSKNCNCQGTRHPVFDIAPNCLHCGKVVCVIEGLNKGKCGHCHEQLISDNER---------------------TQMVEILNQEKNELNGSSSSLSNASNGANVPKKKTKTYKITSGMGKNLFAEQDKLFDFIERKRERERKRNEVLKLQEEKEESEAKERQ-------------------ASEHDHKAEENPELLAAQERLDRLLYFQDTSAERTKIIDNASDFDMN-QEVGLWGSARER--------ALALKKQQRNLRKWEKVEKERNGRREKYVVSMNIGSNGKVTMTEVPKDTENVIAGSDDDISDISDEEDISDLKHIHALKSEINTT--KSLENLHLQSKAWDYERDKKQFDRPTYVKKNSDTAQQNRK--------TEEKAHDMQAYDLKSRVQVDQNADASVEQNILAVL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : : . : :*. .. :: . . ::* .: *: . . .. : : . . : .: . ... :. : .* : : : * : *:* . :* ::: *** **::** ** * * * : : :*. *: . ... : * :.: :. .* . :: :: . * . . :*: . * ..* .* . .* *:. : . :: . : : . : * . * :: * . : .* :.. . *: ... .:: .:.. : .: . : . . . : : : : .: :. . .:: : . . :: : . .. : :: ", "identical_positions": 36, "similar_positions": 148, "identity": "6.0%" }, { "cls_id": "homologset.agr.SGD:S000001732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZZ0-1", "uniprot_id": "A0A8I5ZZZ0_RAT", "id": "A0A8I5ZZZ0-1", "name": "ATP-dependent RNA helicase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MRRQTEATKRKHQVSSDAPPAKRRNEISSLSAKKASNKETQR---AFKGSAHKTFPPKKHLDTIGNERQEEK--PCVKTSSLFKNNPE---------------------------------------------------------------------IPELHRTVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFNR---VRWLVVDEADRILDLGFEKDVTVILNAVN----------AECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKSWDQPNPKE--------------------VASIQLDSFAIPESLDQYVVLVPSKLRLVCLAAFILKKCKFE-------KDQKMIVFFSSCELVEFHYNLFLHTLLC---------HSGTPASETLPSASWPLK----FLRLHGNMKQEERTSVFHEFS------HSGTGVLLCTDVASRGLDLPQVTWIVQYSAPSAPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVSEIKLEGILAVLAKDDCFKRR---------QRGAQRSHATGPQEIRERATVLQTVFEDYVHSSQRMVSWAKKALQSFIRAYATYPKELKSIFHVRSLHLGHVAKSFGLRDAPRNLG-------VSAVR--KASFKRPDPRRKTQRKHHLVPAEVLHSEHSSGLEGNGTKGRKQG--------------LRVAP------------SKPGLRR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZQ2-1", "uniprot_id": "DDX31_MOUSE", "id": "Q6NZQ2-1", "name": "ATP-dependent DNA helicase DDX31", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MKRQAEATKRKHQVSSDAPPAKRRSEISSVLAKKASDKETQR---TFKGSTHKTFPPKKYLDSIGNGRQEEK--PCIKTSSLFKNNPE---------------------------------------------------------------------IPELHSTVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCVPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNLHFNR---IRWLIVDEADRILDLGFEKDITVILNAVN----------AECQKRQNVLLSATLTEGVTRLVDISLHNPVSISVLDKNCNQPNPKE--------------------VASIQLNSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFE-------KNQKMIVFFSSCELVEFHYSLFLHTLLC---------HSGTPTSEHLPSASWPLK----FLRLHGNMEQEERTSVFHEFS------HSETGVLLCTDVASRGLDLPQVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVGEIKMEDILAVLAKDDCFKRR---------QRGAQKSRASGPQEIRERATVLQTVFEDYVHSSQRMVSWAKKALQSFIRAYATYPKELKSIFHVRALHLGHVAKSFGLRDAPRNLS-------VSAVK--KASLKRPHPRRKTQRKQHLVPAEVLHSEHSSGLEGGATKCRKQGK----------QQGLQVAP------------SKPGPWRE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8H2-1", "uniprot_id": "DDX31_HUMAN", "id": "Q9H8H2-1", "name": "ATP-dependent DNA helicase DDX31", "aln": "-----------------------MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGTSPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTFSRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQR---TFKGNAQKMFSPKKHSVSTSDRNQEER--QCIKTSSLFKNNPD---------------------------------------------------------------------IPELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSR---LRWLVFDEADRILDLGFEKDITVILNAVN----------AECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDK-----------AVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFE-------EDQKMVVFFSSCELVEFHYSLFLQTLLS---------SSGAPASGQLPSASMRLK----FLRLHGGMEQEERTAVFQEFS------HSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVSEIKMEDILCVLTRDDCFKGK---------RWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLS-------ALTRKKRKAHVKRPDLHKKTQSKHSLA--EILRSEYSSGMEADIAKVKKQNAPGEPGGRPL-QHSLQPTPCFGRGKTLKWRKTQKGVQRDSKTSQKV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6R7-1", "uniprot_id": "A0ACD6B6R7_DANRE", "id": "A0ACD6B6R7-1", "name": "ATP-dependent RNA helicase", "aln": "-------------------------------------------------------------------------------------------------MAEDTLMLN-------ISSGSVQFNRKTNQKHLSSSEKWAQKKRVAKRKAAVEPQESSASKQRKINQTGQQHAQKQTLQTPRSPSQRSNNRDTEENPVQRENSEAKSPSKVKTFPKKAPTEHEDHGRPFIKTSSLFRNNPE---------------------------------------------------------------------IPDVLSPAVNQVKEKVFTSNTFEELNLHPHLVATLHKVLNVSSMTSVQKQTIPVLMS---GKDAVVRSQTGSGKTLAYGIPMVQFLQAIQPKVKRSDGPLAVVIVPTRELALQSFQMFQKLLRPFTWIVPGVLMGGEKKKAEKARLRKGINVLISTPGRLVDHIKNTLSIAFSA---VRWLILDEADRILDLGFEKDLTVILNALN----------TAGPDRQNVLLSATITEGLSRLASISMKDPVSVHVSEGSEETVEACP------------------QAAPQALSDSYAVPERLQQHVVVVPSKLHLVCLAAFILAKCKFE-------QRQKLVIFISSCEAVEFLLNLFTAVLCE---------IPSNTSSK----STSCLN----FYRLHGNMRQEERTEVFQEFS------QCKTGILLCTDVAARGLDLPQVTWIVQYNPPVSAAEYVHRVGRTARIGAQGSSLLFLTP-SETAFVDVLA-NHNISLSEMKMVDILSTLMKDERFKGRG--------KWDSKRSADAFEQEVRERATLLQTDFENYVHASNESLQTAKSALQCFLRAYTTYPSSLKHIFHIRMLHLGHAAKSFGLRDAPQGLASSISTNPANSKHSKKAKDKAKSPPKKLTAKQRVS--NLMRSEYDSGMDGQSKAKKKRK-------------------------------NKKGQAEESTDA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86B47-1", "uniprot_id": "Y8611_DROME", "id": "Q86B47-1", "name": "Probable ATP-dependent RNA helicase CG8611", "aln": "MVENISLNVTVKSSARKNQQQSPALSVKKRAQKSQDFDFQFNVDKPKVKAIVVRRRAPPSKVEPTNSSVPNTTKSPTPSVSSSKSAISTLSASPKANASNDDLMFNVSPTKPPVKSVLGDDFMLNVTTKPVVAQKAKPKITRAERLGKKQRQGKPLTKLSEEQITRALKSNKKPKNPNQLPTPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIEDSGESGEESATSDEEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKIGLFDQSDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQ---GKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTK---LQFLILDEADRLLELGYERDVKQLVEAIDKQRAECE--DKELPQLQRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASP------KQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQGLR----FFKLHGSMTQTERQGVFRGFR------DCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTP-SEAQFVRHLE-KKRIRIQQGDMYAYLQTLLPKD-----------------------DEARTVQEAASNLQHKFQTLLEDDRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFAAKHAAPKAAPPTNRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGAQKPGAPPPKGGFIGGGVGRSSFMKSLGKSRALNMSEFDSGLPPEGAAKRRKQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36120-1", "uniprot_id": "DBP7_YEAST", "id": "P36120-1", "name": "ATP-dependent RNA helicase DBP7", "aln": "------------------------------------------------------------------------------------------------MSDEDSMLLN------------FTTNEDTAGSSYKQAAKVTGGRWKDRRRMKMKLEGKTVSRKRKANTTGDEGIIPGRGENSIKKLHKESSYSSEEQEKYKGRNAHNTQGRTLPADSQFVSSLFTSNREITTAVNTNIHDEN----------------------------------------------------------------------------VAINPSNAPLKGDQFASLGVSSLLVSHLEQKMRIKKPTSIQKQAIPQIIGNAGKNDFFIHAQTGSGKTLSYLLPIISTILNMDTHVDRTSGAFALVIAPTRELASQIYHVCSTLVSCCHYLVPCLLIGGERKKSEKARLRKGCNFIIGTPGRVLDHLQNTKVIKEQLSQSLRYIVLDEGDKLMELGFDETISEIIKIVHDIPINSEKFPKLPHKLVHMLCSATLTDGVNRLRNVALKDYKLISNGTKKDSD-------------------------------IVTVAPDQLLQRITIVPPKLRLVTLAATLNNITKDFIASGQQSKTLRTIVFVSCSDSVEFHYDAFSGSDGHHKNLTGDSVRLLTKGNTMFPCFSDSRDPDVVIYKLHGSLSQQMRTSTLQHFARDNEATKGKHLIMFCTDVASRGLDLPHVGSVIELDPPFAVEDHLHRVGRTARAGEKGESLLFLLPGEEEKYMDYIQPYHPMGWELLKFDKEILMPAFKDVNVNRNDKFIRKDEKSSKNKDVGDKEYEWDTNATTWHLNIERRVVGDSAFKNLAVKGFISHVRAYATHISQEKKFFNVKFLHLGHLAKSFGLRERPKAMG----------LQSSKDGNSEKKPTKENSKNKMFRMARMAEKQIASEFNY---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : : : : . .. . .. . .. : :. : *.: . : :. : : . **:*:::** :: .* .:::********:* :*::. : .::.*..* *:*:.*****. * :. ..*: ::** *:*** :*:******** *.:*.****::**: * : :::::.**.*::::**::. :. ::: :. . .:* ***:*. : :* .::::: : . *: * .:**.**:** *:: : . : : ::*.* : *:* . : . : :***.: * * .:: * . :::.***..**:*:*.: ::: .* : :.:**:***** * :* ::*:* * .* :: : : : .: : .: *: : :: : . . : ..: . :: *:*. . * :*::: *:** ****.*:: * :. . : . : . : ", "identical_positions": 117, "similar_positions": 203, "identity": "11.43%" }, { "cls_id": "homologset.agr.SGD:S000001733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZT4-1", "uniprot_id": "RPC5_MOUSE", "id": "Q9CZT4-1", "name": "DNA-directed RNA polymerase III subunit RPC5", "aln": "MAN-EEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDG--------ACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEA----GDSSQDEAEEDVKQITVRFSRPESEQ-ARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSN------VLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVD----SVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSAPVGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGAELEAEEEEPMDTAPSTCLSTKLANGLPAGRAVGGDSLNGHPVPGCASNPVACELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHILFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNLIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP45-1", "uniprot_id": "D3ZP45_RAT", "id": "D3ZP45-1", "name": "", "aln": "MAN-EEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDG--------ACTDETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEACFTAGDSSQDEAEEDVKQITVRFSRPESEQ-ARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSN------VLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVD----SVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINRGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGPSAPV--VSGEQRVQTAKTKAQQNHAFLERELQRRKEQIRGTTVLPSVQIKEEPLSEEEADGDELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVARELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVU0-1", "uniprot_id": "RPC5_HUMAN", "id": "Q9NVU0-1", "name": "DNA-directed RNA polymerase III subunit RPC5", "aln": "MAN-EEDDPVVQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDG--------ACADETSTYSSKLMDKQTFCSSQTTSNTSRYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEA----GDSSQDEAEDDVKQITVRFSRPESEQ-ARQRRVQSYEFLQKKHAEEPWVHLHYYGLRDSRSEHERQYLLCPGSSGVENTELVKSPSEYLMMLMPPSQEEEKDKPVAPSN------VLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGPSID----SVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGVPAEVLCRGRDFVMWKFTQSRWVVRKEVATVTKLCAEDVKDFLEHMAVVRINKGWEFILPYDGEFIKKHPDVVQRQHMLWTGIQAKLEKVYNLVKETMPKKPDAQSGPAGLVCGDQRIQVAKTKAQQNHALLERELQRRKEQLRVPAVPPGVRIKEEPVSEEGEEDEEQEAEEE-PMDTSPS-GLHSKLANGLPLGRAAGTDSFNGHPPQGCASTPVARELKAFVEATFQRQFVLTLSELKRLFNLHLASLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEDLSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R866-1", "uniprot_id": "F1R866_DANRE", "id": "F1R866-1", "name": "", "aln": "MASGDDDDPIIQEIDVYLARSLVEKLYLFQYPVRPGSMSYNNVTHLGAKIKPKQQKVELEVAMDTMSPNYSRSKGEQIALNVDG--------MSSEDSNVYTTKMMDKQTFSSIQATTNTSRYAAAVFHKGELHLTPLQGILQMRPSFTYLDKADTKHREREAANEA----GDSSQDEAEDDVKQITVRFSRPESEQ-ARQRRIQSYEFLQKKQAEEPWVHLHYHAIKDSRSEHERQYLYCQAMDTTENTELVKTPREYLSMLMPPLAEEKVVKPVGPSN------VLSMAQLRTLPLGDQVKTLMKNVKVMPFANLMGLLASGTD----STAVLRCIQQVALLVQGNWVVKSDVLYPKNTCSSHSGVPAEVLCRGRDFVMWRFTIERTLMRKEVAAIIKLPPEDVKDFLEQMSVPRLNRGWEFLLPTDQDFVKKHPDVAQRQHMLWTGIQSKLEKVFNFSKDDFVHKKDVQMEPVH-LSGDQRLKAAQENAQEKHSILQRELDAHR--LKASRLSGSQGPSGASVTVKQ----EPVSDSEEPMDTGAA--LTNGSVNGYPAASSPTSDPHNGHG------QAFTPELQDFVKNTFRKHYVLCLSEVKRLFNLHLASLPSGHAAYGHVTDRMLQDTILHSHCKQILVPFPPQSSAAADEQKVFGLWESGETFDKLRQILFEIFMKNYRVRRNVIQTRLTQELGDAVNKTDVDRLLKECCISLGGMWYLKGTVHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP85-1", "uniprot_id": "Q9VP85_DROME", "id": "Q9VP85-1", "name": "", "aln": "--MEDEDDPVVEEIPVFLSKNLRDSLYLFQYPTKTELPNHDDSVIVNCCVKPIAQEVKVDFGLDIESAHFDRFKGEQFAVAADGKNTYGAVPPKGQERPTYKRGIMDKQAFTSSRSITDVAKYIVGIFTDREVHLSPLTSIVQMRPVLSHFDKDDKRKKAELKAQTE--------DTDDDEVLQQVTVKFARGNAKNSGKEQRVGTYDSFVQRIADEPWCEAYWHSRGTPTAELERQKLFATSHHGSS--SLALAPDEYLRKLLPYDEHVQTVAPAAASAAAQVLPVYNKAMLKSMPLLEQLTVLLRDARMLSFSDVISILAEHVDPHVAADKVLALLPQVGILLHGNWVPKSEVVFPEKVLSHANGVSAEQMIRARDYILFRFSRTPYLFRAQVMAATQLPPAETLDVLKTVARVNNTKRWELLLPPDKEFEQKYPELVSRQEYHWTASEQHYNEMDWARETKRVRKRSTR------KSESQSLTSAMPPPAMNHSTTGSVDA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36121-1", "uniprot_id": "RPC5_YEAST", "id": "P36121-1", "name": "DNA-directed RNA polymerase III subunit RPC5", "aln": "-------------------------------------------------------------------------------------------------------MSIDNKLFVTEEDEEDRTQDRADVEDES----NDIDMIADENGTNSAIANEQEEKSEEVKAEDD-----TGEEEEDDPVIEEFPLKIS-GEEESLHVFQYANRPRLVGRKPAEHPFISAARYKPKSHLWEIDIP-LDEQAFYNKDKAESEWN-----------GVNVQTLKGVGVEN------------------NGQYAAFVKDMQVYLVP----------------------IERVAQLKP----------------------------------FFKYIDDANVTRKQEDARRNPNPSSQRAQVVTMSVKSVNDPSQNRLTG-SLLAHKVADEEANIELTWA------EGTFEQFKDTIVK-----------EAEDKTLVALEKQEDYIDNLV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: * : . : :: . : . . : * : . : : : : .: . *: : : : :::..:::: : :. : . :: *:.*: : * : * . . . . : .. . * :::: :: .. : :*. * :::: : * : : : . . : :: . : *. : :* .: . . *: : : : . .: : . ", "identical_positions": 15, "similar_positions": 97, "identity": "2.04%" }, { "cls_id": "homologset.agr.SGD:S000001734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64270-1", "uniprot_id": "EI2BA_RAT", "id": "Q64270-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIKYFKSQMKGDPNMASAVAAIQTLLEFLKRDKGETIQGLRAHLTKAIETLCAVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLSRISLSRTKIASLCHAFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQAGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC8-1", "uniprot_id": "EI2BA_MOUSE", "id": "Q99LC8-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIEYFKSQMKGDPKMASAVAAIQTLLEFLKRDKGETLQGLRANLTYAIKTLCGVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIANLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALSHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQEDVPDKFKYKADTLKSVQTGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14232-1", "uniprot_id": "EI2BA_HUMAN", "id": "Q14232-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MDDK---ELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVA-VSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEH--PWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILD9-1", "uniprot_id": "A0A0R4ILD9_DANRE", "id": "A0A0R4ILD9-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEER---ELVEYFRGQIREDPDVASAVAAIRSLLEFLKRDQSETILGLRENMTQAIHRLQEADSSVA-VSSGGELFLRFISLTSLEHPDLSQCKNVMIERGELFLKKISLSRGKVGKLCHTFIKDGAKILTHSSSRVVLKVLENAAADNKRFTVYVTESQPDSAGKLMAEKLRKLSIPVTVVLDAAVGYILEKVDLVIVGAEGVVESGGVINKIGTYQMAVCSKAHNKPFYVVAESFKFVRLYPLNQQDVPDRFKYKADVLK---TAEDLNQEH--PLIDYTPPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAD4-1", "uniprot_id": "Q9VAD4_DROME", "id": "Q9VAD4-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "MPQITENGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLS-LDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYSRKHLN------DVSKVH--PLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLYM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14741-1", "uniprot_id": "EI2BA_YEAST", "id": "P14741-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "---MSEFN----ITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLP----MAGPPLDFTRRTDDLEDALRGPTIDYTAQEYITALITDLGVLTPSAVSEELIKMWYD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : * .:: :***.:*: :*. . * : : : : . . : :. ::* **: . .:*:: :::.*::*: : ** :.. ** *. **.*. **.*: * * * :*:. .. *: : * .: *:::*:*.* :::..* *:****.*.*.**:** :** :.: :: .*****::**.** *::**.. *:* *. *:.. * :***. ** *:**** *******:****:: ", "identical_positions": 86, "similar_positions": 97, "identity": "27.22%" }, { "cls_id": "homologset.agr.SGD:S000001736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q922D4-1", "uniprot_id": "PP6R3_MOUSE", "id": "Q922D4-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "aln": "---MFWKF---------------------------DLHSSSHIDTLLEREDVT----------------------------------------LKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEE--------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQVQNST-------EPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENA-------------------ENGTIT---DQDSTGDNLLLKHLFQKCQLIERILEAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIK----DLPDEVRERWETFCTNSLGETNKRNTVDLA------------------------------FSDYQMQQMT-----SNFIDQFGFNDEKFADQD-----------------DIGNVSFDRVSDINFTLNTNE----------SGNIALFEACCKERIQQFDDG----------GSDEED----IWEEKHIAFTPES--------------QRRS-SSGSTDSEESTDSEEEDGAKQDLFESSSANTEDKMEVDLN-------------EPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKESLRSNSPVEMETS-TESVDPLTPGAAA--------LATQPEAPGSMAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK------SEEEKLSTSQDAACK--------DAEET--------------PEPAEAKCTAPL----TPSSSPEQRTDQPSMPSD---------PSVNGPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAH5-1", "uniprot_id": "F1MAH5_RAT", "id": "F1MAH5-1", "name": "", "aln": "---MFWKF---------------------------DLHSSSHIDTLLEREDVT----------------------------------------LKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEE--------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQVQNST-------EPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENA-------------------ENGTIT---DQDSAGDNLLLKHLFQKCQLIERILDAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIK----GLPDGVRERWEAFCTDSLGEANKRNTADLVTTCHIHSSSDDEID-FKDTGFSQDSSLQQAFSDYQMQQMT-----SNFIDQFGFNDEKFADQD-----------------DIGNVSFDRVSDINFTLNTNE----------SGNIALFEACCKERIQQFDDG----------GSDEED----IWEEKHIAFTPES--------------QRRS-SSGSTDSEESTDSEEEDGAKQDLFESSSANTEDKMEVDLN-------------EPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKESLRSNSPVEMETS-TEPVGPLTPGAAA--------LASQPEAPGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK------SEEEKLSTSQDAACK--------DTEET--------------PESAEAKCTAPR----TPNSSPEQRTDQPSMPGD---------TSVNGPV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H9R7-1", "uniprot_id": "PP6R3_HUMAN", "id": "Q5H9R7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "aln": "---MFWKF---------------------------DLHSSSHIDTLLEREDVT----------------------------------------LKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEE--------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNST-------EPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENT-------------------ENATIT---DQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIK----DLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEID-FKETGFSQDSSLQQAFSDYQMQQMT-----SNFIDQFGFNDEKFADQD-----------------DIGNVSFDRVSDINFTLNTNE----------SGNIALFEACCKERIQQFDDG----------GSDEED----IWEEKHIAFTPES--------------QRRS-SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLS-------------EPPNWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETS-TEPMDPLTPSAAA--------LAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK------SEEGKLSTSQDAACK--------DAEEC--------------PETAEAKCAAPR----PPSSSPEQRTGQPSAPGD---------TSVNGPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWD3-1", "uniprot_id": "A0A8M3AWD3_DANRE", "id": "A0A8M3AWD3-1", "name": "", "aln": "---MFWKF---------------------------DLHSTSHIDTLLEKDDVT----------------------------------------LTEVMDEEDVLQECKAQNHKLVDFLVRPQCMEDLVVYITQE--------------------------------------------------------------------PNDDVEEKIKYKYPNISCELLTSDVGQINDRLGEDESLLMKLYSFLQNEPPLNPLLASFFSKVLSILIGRKPEQ-----------IVEFLRKREDFVDLMIKHIGTSAIMDLLLRMLTCIEPQQLRQDVLNWLNEEKVIQRLVDMVQPSQDEDRHSNASQSLCEIIRLSRDQMFQVQGSS-------EPDPLLATLEKQETVEQLLSNIFDKEKNESAIVSVIQILLTLFETRRP------------AFEGHLEICPPGMNHPSFSVNQSILDAVRPRLKDFHQLLLEPPKKTVLNTTWGVLDPPVGNTRLNVVRLVTSLLQTNTHIINQELIALNTLGVILDMYFKYLWNNFLHTQVEICTAMVLAMPSTQS-------------------ESPEINRENDQEPIRENILIKHLFQKCQLIQRILDAWGSNDKEQTEGGRRRGYMGHLTRIANSIVHNSDKGPNGSQIQQLISGLSIELPEEDRERWEAFTSGQLADTNKKNTVDLVNTHHIHSSSDDEVD-FKDSGFHQDSSLQQAFSDYQMQQMT-----SNFIEQFGFNDEEFADQD-----------------DVGDIPFDRISDINFSLNTNE----------SANVALFEACCKEKIQQFEDA----------GSDEED----IWDEKDVTFAPEA--------------PRRPRSSGSTDSEESTDSEEEDG-KRDPFESTNATSDDRMEVDSG-------------DGTVWTANFDDIPMDTGSSTAPSAPVSNSTASVPESTGWSSPNASGDGETGWADFSSFTP-VSPKDPLRCNSPVAMETS-IETVDPLGVNAPMQQENTDQWLPNETTPTSPRGKTGDASDPEEEPVSDRITETVTNGSMKETVSLTVDAKTETAVFKRVLKSYREEEKQSTSEDASAKL-FVAESGDAEKSNCPSSNCQKPGLKHLEKAKSPCEALNGPLEDAADMDEAKSEQCTANPE---------AAVNGPA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R3Q2-1", "uniprot_id": "PP6R2_MOUSE", "id": "Q8R3Q2-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 2", "aln": "---MFWKF---------------------------DLNTTSHVDKLLDKEHVT----------------------------------------LQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVNLITQD--------------------------------------------------------------------PPQDMEEKVRFKYPNTACELLTCDVPQISDRLGEDESLLNLLYDFLDQEPPLNPLLASFFSKTIGNLIARKTEQ-----------VIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKIIQRLVALIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-------EPDPLLITLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRV------------GTEGLVDSFSQGLER-SHSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPGINQELCRLNTMDLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREEQAEASGSDGKVEPLQGSGDGNGKLETTPSITSPPENTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISEVIR----GLPADCRGRWESFVEETLMETNRRNTVDLA------------------------------FSEYQIQQMT-----ANFVDQFGFNDEEFADQD-----------------DNINAPFDRIAEINFNIEADED---------SPSAALFEACCSDRIQPFDD------------DEEED----IWEDDETRCAARV--------------MARARFGAPHVSDNYSKNALEHGGQDRKTGSAVARNVPGLAAPSSPTQKEGPRSESDSAGTTWTAVFDEPVNPLSATPGAARDVG--------SSAWAAG-PSVVEEKGWAKFTDFQPFCCSETGPRCSSPVDMDHSNAEGGQSPGPEKTFGPTSPCAWNVCVTRKAPLVASDSSSSGGSDSEDDEKAAGAVEAVCTGHTGKVSPPPRTAEAAVG------RAECPDSTVLAPACPAPSEVTISPAVATIAPSKAGSPTATIVVSSSVAAAVPPGPIVAVTTAAPAIVATLGTMTKDRKADALPEGAALNGPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSI3-1", "uniprot_id": "PP6R1_MOUSE", "id": "Q7TSI3-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "aln": "---MFWKF---------------------------DLHTSSHLDTLLEKEDLS----------------------------------------LPELLDEEDVLQECKVVNRKLLDFLLQPSHLQAMVAWVTQE--------------------------------------------------------------------PPASGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSGDSLNPLLASFFSKVMGILINRKTDQ-----------LVSFLRKKDDFVDLLLRHIGTSAIMDLLLRLLTCVERPQLRQDVFNWLNEEKIVQRLIEQIHPSKDDNQHSNASQSLCDIIRLSREQMIQGQDSP-------EPDQLLATLEKQETIEQLLSNMFEGEQCQSVIVSGIQVLLTLLEPRRPRSDSVTMNNFFSSVDGQLELLAQGALDDALSS-MGALHALRPRLDRFHQLLLEPPKLEPLQMTWGSLAPPLGNTRLHVVKLLASALSANAAALTQELLVLDVPNTLLDLFFHYVFNNFLHAQVEVCVSAMLSSGPPPD---------------------------SSSETPVPNPIVKHLLQHCRLVERILASWEENDRVQSGGGPRKGYMGHLTRVANAVVQNAEQGPNAEQLGQLLK----ELPEEQQQRWEAFVSGPLAETNKKNTVDLVNTHHLHSSSDDEDDRLKEFNFPEEAVLQQAFMDFQMQRMT-----SAFIDHFGFNDEEFGEQE-----------------ESVNAPFDKTANITFSLNADDE---------NPNANLLEICYKDRIQQFDDEEEEE--EEGQGSAESDGEYGAWQGSQPVRASQAS------------QPPGVRSGGSTDSEEEDEEEDEEED--EGAEQAACGRTSPSSFPSPSTQ---------PPGPSWTATFDTVPMDAPTGPPVSKEAD-------MSS--------IQIPS--------SPPAHGSPQLRSQDPTHPSAP------------------------QEVTDSSKVAEPLAPCQALVSVADVQATLHGMRSAPSSLDSATRDPSTSVPDFK-------AHQSPQTMEGKRSP--------EHLG--------------LPQSQSALEMP-------NGSTPGGPISSGSQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPN7-1", "uniprot_id": "PP6R1_HUMAN", "id": "Q9UPN7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "aln": "---MFWKF---------------------------DLHTSSHLDTLLEREDLS----------------------------------------LPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAWVTQE--------------------------------------------------------------------PPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLLASFFSKVMGILINRKTDQ-----------LVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQDVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSP-------EPDQLLATLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLELLAQGALESTVSS-VGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVKLLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPD---------------------------SSPETPIQNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEKGPNAEQLRQLLK----ELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKEFNFPEEAVLQQAFMDFQMQRMT-----SAFIDHFGFNDEEFGEQE-----------------ESVNAPFDKTANITFSLNADDE---------NPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLG------------QPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQ---------PPGPSWTATFDPVPTDAPTSPRVSGEEE-------LHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAP------------------------QEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASG-------AHQPPQTTEGEKSP--------EPLG--------------LPQSQSAQALTPPPI--PNGSAPEGPASPGSQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PEH8-1", "uniprot_id": "M9PEH8_DROME", "id": "M9PEH8-1", "name": "", "aln": "---MFWDK---------------------------GYAPSANIEALLEKENST----------------------------------------LEEFLDEEDILQECKTQKKNLVNYFTRPEVIRRLVELITTE--------------------------------------------------------------------PSEDVPMSKRFRYANMSCEILTLGLPSLDEKLLNDAETLQLLYSYLEKEPPLNPLLSSFFSKTFSMLFTKKPEQDWFLYQHMCLQLLEYIKSQKTFLDFICKHFDTPVIPDLIMQMMKDIEGGRLKRNLFEWLTEDKIVERLIAILRNPQETDKHANVADFFCDLINQGRLMRQTEQENDSFEPAFDGSNPILKTIEFADTIEALLNVILEPNAQESAILSGISVVLTLIKPITFTDE---------PNSDRQRLLQKREREIHQEVQETVITVMAPRLQEFVHILKNPPAKPTLETTAAVLTPPFGKTRLQVCRVFTALLETKHETIQQAICATEYFSLLLDFFKQYCWNNFLHTEMEKALYVVFYNELSNN----------------------NTASTEVTDYFTADCLINAFLKVGTEESEVEMKNALNDAKRAEGG-KDEEGGDIEIEVAAAQEVAAQTPDERQTAAEENQEHEEHMSQVEAAAEATASEDAEPKAQDNEVKNSEVDGESPTDQQESEATLNDLDKTKTVPSPPPSEMQSHLIVNCHLISKLVDLWQHNAQAQSAEKGRRLGYMGHLIKILRHITNCISESEHIGDLITSSLSDEDEVKLWQSLIDAETGEFSLAVKQQTKLLADCNPHEENQYNDGSNDYTGEINAWNVGNLPYREVDCSELNNTLQDIFFAIDQNRFQFGRNIDDEDDDDDEHGDHSGGGDGHGHGMFTKNSNTLNN------------LADPWDIQFAVLSSAPTQVNTGTANWG------TDFNSDNFADFDAHFSTFGSDLGMPISAPPGEEEEEDSSPAPESATQVNPEEERQPAESIG-------LAVGKGVQDNLACTDDQQAEYDNNANVEKAISDKLAESSVVETAAIVTRLQSVLLDGEDDYEDDEGMWTKPLGADRPS-----ETEQITPISNGPDSKVNELGLPFSNHANDISSNNVDGHEANITTEQQKLAAAAKTNN-------VEIATTTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36123-1", "uniprot_id": "SA190_YEAST", "id": "P36123-1", "name": "SIT4-associating protein SAP190", "aln": "MSGSFWKFGQDYSIESPVSKILNSAFIKINKDQDDDVPTGTCEENIADDEDNSSHDYAASEDNVVNENEEKEEENTLPTTESEYENYRPNLDVLDDLLDDDELYTELMCSNFKLLIFLKYPDVLSKLIEYVTNEKILDEETDSAKKPEIIEGVNDHPILIERDRKDKKEDAEEGGDSEETTNDSDHDSGDERSVDSEETSITLPPESEEQVETRRARIAAEILSADVWPISAAIMQNKDLLGRLWSILDHPAPLPIPASTYFMKINERLLDMDITG-----------MLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSPTG-VIKILKSQELIPKLLDHLNPEYGISTQSAAGDFIKAFVTLSTNSSNELASGIG-------PNELTRQLVSEEMIEKLIKIMLKGG---TSLSNGVGIIIELIRKNNSD---------YDFIQLVYTTLESHPPTDRDPIHLIHLVKLFAKHMPDFADMLDKTKLPLMEMPFGNIEP-LGFERFKICELIAELLHCSNMTLLNEPNGE-MIAQERDIERAKELETSTEKENITAIVDNKSSYYDKD---------------------------CVEKDITENLGALQINNQGSEEDELNDTGVSSVKLDVKSDAKVVEG--LENDASGVELYDETLSDTESVRECLR----EKPLVGDRLKIALEDTKILISILDMFTEFPWNNFLHNVIFDIAQQIFN------GPLKTGYNRFLLKDYLVD---AYLTKKIVDADKACQDYE-----------------KKTGLRYGYMGHLTLVAEEISK------FKEYIDEMKLTFCNTAVSDRLEEPFWKEYSETILADTREKYNTVLGDFGNDQESDDDVIR----------NSDSEDIIGDTEGNENYGNGENDELLSNGHDSGNMDLYYNFNNNENE------------ENEEDYAEYSDVDNKNYYNNVETNDDD------YDSDDGKSKSAESEFTDKISEHRDGNSLYNEDNDENGSDKWTSGTSLFPPDHFPSRSQPSDP------KLQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTPKTPPRPKTILFNSLSALDNNGEDEEVALGTSVD--------DRMDN---------------EISSDEEDSEDEDEENDMGNEEGYSLYRSRSKEAF---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. . . : : : : :. : * :.:*:::: * : :*: :: : :: : : . . : . :.*:*: .: :. : : . * *:. * .* :::* * *: . :: :: .: :: : *.... : *::::::. : :.. *..:.:: :*: :. . :: ..: : :: . .: : : : :* *:. ::. : : . : ::: *:. . : : : : . : . . : .* *:: .:.: * . : :: :. . : . : : : ..: . .. : : . . : .. : : : . : . ..: . . : . . . : : . : . :: . :. : . . .. . . . . : ", "identical_positions": 25, "similar_positions": 192, "identity": "2.08%" }, { "cls_id": "homologset.agr.SGD:S000001737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2W7-1", "uniprot_id": "D4A2W7_RAT", "id": "D4A2W7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVLRDPIKKNSSESKPAQSGFSRGNSPLCC-------------PESVEASP--------------------------------AVNEKS---LYSTHNYGTTQRHGCRGLPYAD----------HNYGAPPPPTPPASPPVQTIIPRSDLNG----------LPSPVEERCGDSPNS-------EGETVPTWCPCGLSQDGFLLNCDKC----------------------------RGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYT------------------------------------ATQHTPTSITLTVRRTKP---KKRKKSPEKGRAAPKTKKIK-------------NSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHS-NKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNG-----------------HFFKKPYPFVLFYSK--------------------------FNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCN------------YKVDCACHKG----------------------------------------------------------------------------------------------------------------------------NRNCPIQK--------------------------------------------------------------------------------------------------------RNPNAAELP-LPPP-SFPTIGAETRRRKAR-------RKELEMEQQNEVPEENHDPQPQEVPEKVTV------------------------------------SSEHEEVDNPEEKPEEE-KEEATDDQENSAHSRRT--------------------------------------------------------------------------------------------------------------------------------REDRKVEAIMHAFETLEKRKKRRDQPVEQSNSDVEITTSSSEIG-VGEETKTAAPESEVNNPVTNIAIPSIPQS---------------------TGVNTRRSSHAGDVAAEKPVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELAQAALEE-GGSNNSVTLPEAGNIDSSGESRPLTGSDPTVVSVTGSHVNRAASKYPKTKKYLVTEWLN-----DKA-EKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFMPER-----------RRRPLLPDG--TFSSCKKRWIKQALEEG--------MTQTSSVPQETRTQHLYQSNENSNSSSICKDNADLLSPLKKWKSRYLMEQNITK---LLRPLSPVTPPPPSSGSKS--PQLTTPGQTHPG-EEECRNGYSLMFSPITSLTTASRSNTPLQFE-------------------LCHRKDLDLTKVGYPDSSTHSCGDRPSLLNCSHPDLTSHPSVAPTS------------------EAGFPSRSGDGPQTLLRNS------DQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS--------PAEGFSSRYEHGFMKDLSRGSMSPGGERTCEG-----VPSAPQNPPQRKKVSLLEYRKRKQ--------EAKEN-SGGGSDSSQSKSKSSGAGQGS--------SNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSTSH-------------------LEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG-GSIPKVLRSSVRVAQKGEPS------------------------------------------PTWESNITEKESDPADGEGPEPLSSALSKG--------------------------------------------ATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS-PFRGHPTQSPGYSYRTTA----------LRPGNPPSHGSSE------------------------------------------------SSLSSTSYPSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSNLPRRSCSSSAASPTP-----------------------QGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA-----------------------------------------------------------------------------------------GQSAAYQASRVSAVSSSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJV7-1", "uniprot_id": "SETD5_MOUSE", "id": "Q5XJV7-1", "name": "Histone-lysine N-methyltransferase SETD5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIAIPLGVTTPDTSYSDMAAGSD-----------------PESVEASP--------------------------------AVNEKS---VYSTHNYGTTQRHGCRGLPYA-----------------------------TIIPRSDLNG----------LPSPVEERCGDSPNS-------EGETVPTWCPCGLSQDGFLLNCDKC----------------------------RGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYT------------------------------------ATQHTPTSITLTVRRTKP---KKRKKSPEKGRAAPKTKKIK-------------NSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHS-NKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNG-----------------HFFKKPYPFVLFYSK--------------------------FNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCN------------YKVDCACHKG----------------------------------------------------------------------------------------------------------------------------NRNCPIQK--------------------------------------------------------------------------------------------------------RNPNAAELP-LPPPPSFPTIGAETRRRKAR-------RKELELEQQNEVPEENPDPQPQEVPEKVTV------------------------------------SNEHEEVDNPEEKPEEEEKEEATDDQENSAHSRRT--------------------------------------------------------------------------------------------------------------------------------REDRKVEAIMHAFESLEKRKKRRDQPVEQSSSDIEITTSSSEIV-VGEETKTAAPESEVSSPVSNVAIPSTPQS---------------------TGVNTRRSSHAGDVAAEKPIPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQAIAQQAELSQAALEE-GGSNNSVTPPEAGNTDSSGENRQLTGSDPTVISVTGSHVNRAASKYPKTKKYLVTEWLN-----DKA-EKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFMPER-----------RRRPLLPDG--TFSSCKKRWIKQALEEG--------MTQTSSVPQETRTQHLYQSNETSNSSSICKDNADLLSPLKKWKSRYLMEQNITK---LLQPLSPVTPPPPSSGSKS--PQLTTPGQTHPG-EEECRNGYSLMFSPITSLTTASRSNTPLQFE-------------------LCHRKDLDLTKVGFPDSSTHSCADRPSLLNCNHPDLASHPSVVPTS------------------EAGFPSRSGDGPQTLLRNS------DQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS--------PAEGFSSRYEHGFMKDLSRGSMSPGGERTCEG-----VPSAPQNPPQRKKVSLLEYRKRKQ--------EAKEN-SGGGNDSSQSKSKSSGAGQGS--------SNSVSDTGAHGVQGSSAGTPSSPHKKFSPSHSSASH-------------------LEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG-GSIPKVLRSSVRVAQKGEPS------------------------------------------PTWESNITEKESDPADGEGPEPLSSALSKG--------------------------------------------ATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS-PFRGHPTQSPGYSYRTTA----------LRPGNPPSHGSSE------------------------------------------------SSLSSTSYPSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSNLPRRSCSSSAASPTP-----------------------QGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPNA-----------------------------------------------------------------------------------------GQSAAYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0A6-1", "uniprot_id": "SETD5_HUMAN", "id": "Q9C0A6-1", "name": "Histone-lysine N-methyltransferase SETD5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIAIPLGVTTSDTSYSDMAAGSD-----------------PESVEASP--------------------------------AVNEKS---VYSTHNYGTTQRHGCRGLPYA-----------------------------TIIPRSDLNG----------LPSPVEERCGDSPNS-------EGETVPTWCPCGLSQDGFLLNCDKC----------------------------RGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYT------------------------------------ATQHTPTSITLTVRRTKP---KKRKKSPEKGRAAPKTKKIK-------------NSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHS-SKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNG-----------------HFFKKPYPFVLFYSK--------------------------FNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCN------------YKVDCACHKG----------------------------------------------------------------------------------------------------------------------------NRNCPIQK--------------------------------------------------------------------------------------------------------RNPNATELPLLPPPPSLPTIGAETRRRKAR-------RKELEMEQQNEASEENNDQQSQEVPEKVTV------------------------------------SSDHEEVDNPEEKPEEE-KEEVIDDQENLAHSRRT--------------------------------------------------------------------------------------------------------------------------------REDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETP-VGEETKTEAPESEVSNSVSNVTIPSTPQS---------------------VGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEE-GGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLN-----DKA-EKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPER-----------RRRPLLPDG--TFSSCKKRWIKQALEEG--------MTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTK---LLRPLSPVTPPPPNSGSKS--PQLATPGSSHPG-EEECRNGYSLMFSPVTSLTTASRCNTPLQFE-------------------LCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTS------------------ETGFPSRSGDGHQTLVRNS------DQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS--------PAEGFSSRYEHGLMKDLSRGSLSPGGERACEG-----VPSAPQNPPQRKKVSLLEYRKRKQ--------EAKENSAGGGGDSAQSKSKSAGAGQGS--------SNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSH-------------------LEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG-GSIPKVLRSSVRVAQKGEPS------------------------------------------PTWESNITEKDSDPADGEGPETLSSALSKG--------------------------------------------ATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS-PFRGHPTQSPGYSYRTTA----------LRPGNPPSHGSSE------------------------------------------------SSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTL-----------------------QGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA-----------------------------------------------------------------------------------------GQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFY2-1", "uniprot_id": "A0A8M9QFY2_DANRE", "id": "A0A8M9QFY2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIVITLGVTTPETPYTDMAAGSD-----------------PESVEASP--------------------------------AVNEK----NYSSRSCGNTQSHGYGGLPYAMQQSSVVCCQDHNYGAPPPPTPPASPLSQTVFSHAERNGTLGR--SRPCFSTNEPDNSADSESSSEEEEVVEGAIPPSWCSCHLNQDGFLIKCENC----------------------------RGLEKKKGVDGQRRKAENVSVGESSATESGDEDMSASAVSYT------------------------------------ATQHTPTSITLTVKRVKHNKVKKRKKSTEKTRTTPKAKKVKAYREGSRKSMRMKNSASETSVLDENTTEGWETRIRQWTDQYEEALANQYSADVQTLLEHYCANGNSSPSPSTVAMDTINRTELACNNTVLGSQMQLQLGRVTRVQKHRKILRAARSLDPETLIIEYRGKVMLRQQFEVNG-----------------HFFKKPYPFVLFYSK--------------------------FNEVEMCVDARTFGNDARFIRRSCTPNAEVRHMIAEGMIHLCIYAVAQISKDSEVTIGFDYEFSCCN------------YKVDCACHKG----------------------------------------------------------------------------------------------------------------------------NQDCPVQR--------------------------------------------------------------------------------------------------------HNLRPLELL-SPQPSQFALPGAETRRRRAR-------RRELEGDKLVTGISDESNHLLEDGNEAHGV------------------------------------SDTEDAIMN---RVKLENGEEELDENGALTPNRRS--------------------------------------------------------------------------------------------------------------------------------REERKAEAIMHMFENLERRKKRGQVTAQAAAEETKLEAGEAEVPSAGNCVPNAAAAGGVCTRRSSFVTLDT------------------------ADIDSEKPP-----ATPSPAPKPQPARSSKPRPKSRISRYRSTSAQRARRQRQALSQQAAEGVVVGGE-EGS-AAAGLKEQGQGEGAPNCGHLQDGELYGAASSG-MGNKTHVRHPKTKKYLVTEWLN-----DKVPERVEESVERPLRITTDPTVLATTLNMLPGLSHSPLICTTPKHYVRFGSPFNPER-----------RRRPCMIDP--SYGSCKKRWMKQALDES--------MLSG-LLEDGTESNSSHKSNTSSTSSSVPLK-PELIGPFKKRKLKCSSETAAPPSELLLRPLSPITPPLPSEYPITPLPSLLNPCSLYLGGEVEKRNSTVLSYSPLTSR-PASRCNTPLQFENISSPEASPVHISESLTPDPCLRSDFTSRVPAFPDFSTSRESPAPVSEDFSLPAPDSLNGSGGGT------------------PRSSAVVSTLCDSALVSHASETQTREQAFRTEFNLIYTCSPLNAN-----LPTGP--VSDRQFSQADGGFSI--------ADSDFSTVCNQGLLMEVGSASPSLYLDTQFGGYSESSTSPHPSNPPQKKKRVMVSAASQLAGLSGYQALAVRGQFKPGQNMVSLLEYRERKKGPRDPAPLVTNLSSICPRTESPGQLRTHFQPAVSPHHSFSPERQTFPQ-------------------IEEISPPAVR--SGNHTK-----SNHWMVPTSVERLREGQGALERVLRGNLNIERALKRA------------------------------------------DAGINDQISSQDKSSDVVEMDRLSSLASPTK-------------------------------------------SPSVHPHQQMLPLKPESHQHLESPAYDQQSSSSPFCPSVSPSP---PRSSS----------GGPAYFPSKLPTH------------------------------------------------SPLALGSPSS--STVSISSVDSTVCAP-HAAHSSSAGAMDTSSLKAKLLDSTLSAAIC-----------------------MPARGHLKLDSASVPQTQGAHGSRLAQTSR----------TQSQR-----------------------------------------------------------------------------------------TDRANQANSRHLTSPGAQHYPQRN-----------LQGSGVWTQSGSF-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UG20-1", "uniprot_id": "KMT2E_MOUSE", "id": "Q3UG20-1", "name": "Histone reader KMT2E", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIAIPLGVDTTETSYLEMAAGSE-----------------PESVEASP--------------------------------VVVEKSNSFPHQLYTSSSHHSHSYIGLPYAD----------HNYGARPPPTPPASPPPSGLISKNE----------VGIFTTPNFDETSSATTISTSEDGSYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQ-HIPDTYLCERCQPRSLDKERAVLLQRRKRENMSDGDTSATESGDE---VPVELYT------------------------------------AFQHTPTSITLTASRVP-KVTDKRRKKSGEKEQ-NFSKCKKAFREGSRKSSRVKGSAPEIDPSSDSSNFVWETKIKAWMDRYEEANNNQYSEGVQREAQRLAQRLGSGNDSKDMNKSELSTNNSLFRPPVES-----------HIQKNKKILKSAKDLPPDALIIEYRGKFMLREQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FHGLEMCVDARTFGNEARFIRRSCTPNAEVRHEIEEGTIHLYIYSIQSIPKGTEITIAFDFDYGNCK------------YKVDCACLKE----------------------------------------------------------------------------------------------------------------------------NPECPVLK--------------------------------------------------------------------------------------------------------RSSESTENINSGYETRRKKGKKEKDTSKEKDIQNQNMTLDCEGTNNKIRSPETKQRKLSPLRLSVSN------------------------------------NQEPDFIDDMEEKTPISNEVEMESEEQIAERKRKM-------------------------------------------------------------------------------------------------------------------------------TREERKMEAILQAFARLEKREKRREQALERISTA-----KTEVKPECKESQVIADAEVVQ------------------------------------------------EQVKEETAIKPAAAKVNRTKQRKSFSRSRTHIGQQRRRHRTVSMCSDIPPSSPD---IEVLSQQNEIENTVLAIEPETETAVAEIIPEAEVPALNKCPT--KYPKTKKHLVNEWLSEKNEK--TGKPSDSLSERPLRITTDPEVLATQLNSLPGLTYSPHVYSTPKHYIRFTSPFLSEK-----------KRRKETTEN--ISGSCKKRWLKQALEEENSTILHR---YHSPCQERSRSPTVNGENKSPLLLSDSCSLPDLTTPLKKRRLYQLLDTAYSES--STPTPSPYATPTHTDITP---TDPAFATPPRIKSDDETYRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEIKRCTYNQEGYDRPSNMLTLGPFRNSNLTELGLQEIKTIGYTSPR-SRTEVNRPCPGEKESVSDLQ-LGLDAVEPAALQKSMETPAHDRTEPSNQLDSTHSGRGTMYSSWVKSPDRTGVNFS-VNSNLRDLTPSHQLETGGGFRVSESKCLIQQDDTRGMFLGAAVFCTS-EDGLASGFGRTVND-NLIDGSCTPQNPPQKKKVSLLEYRKRQR--------EARKSGSKPENFALISVSPHPSGSLSSSGD-----GCVHSSENGEQAENQASLPLPPPAAAAAATAAAAYS-------------------ASSEEGSSNCPVKDANSSEKKDPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSPPSSHSNHIPQVHAQSLAPSLSELMADPDAEGTEATSTSECPSPDTSQSPSKTSKPGSPGPINPAQSHGKILTKPDSHWEATATVSEADNSVHQNPEPQHRQLSSNTPALSQNHAPQAHALSANDQLPQKLPSAPTKLHCPPSPHTENPPKSSTPHTPVQHGYLSPKPPSQHLGSPFRPHHSQSPQVGTPQRETQRNFYAAAQNLQANPQQATSGALFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGSTSQQSVPGHHVTPGHFLPSQNPTIHHQPAAAAVVPPPPPPPPAPGPHLIQ---QPSSHQQHSVAHGVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPTTGLQSLQAQHQHVVNSAPPPPPPPPPPPPASVLVSGHHSASGQALHHPPHQGPPLFPASAHPAVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVAGPHLQPQGPNSIPTPTASGFCPHPHPGSVALPHGVQGPQQASPVPAQIPIHRAQVPPTFQNNYHGSGWH------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q6C7-1", "uniprot_id": "A0A8M9Q6C7_DANRE", "id": "A0A8M9Q6C7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIVIPVGVDTANTSYLDMAAGSE-----------------PESVEASS--------------------------------VVVEKS-TYPHQIYSSSSHHSHGYIGLPYAD----------HNYGARPPPTPPASPPPSVLIRPGESLFVSGSRPGENLFVPGGQDEASRGTTLSTSEDGSYGADITRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQ-HIPETYLCERCQPRTLDREHAILLQTRKRENMSDGDTSATESGDE---VPLELYT------------------------------------AFQHTPTSITLTTARLGNKQADKKRKKSGEKEPPATARAKKSFREGSRKSSRVKGSAPECEPIDPPS--LWENKMKSWMERYEEASSNQYSEEVR-----LLLRVKEARDGKTLAYN---THTAAFKPPVES-----------QVQKNKRILKAVRDLAADSLIIEYRGKVMLRQQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FDGLEMCVDARSFGNEARFIRRSCTPNAEVRHVIEEGMLHLYIYSLRSISKGSEITIGFDYDYGSCK------------YKVDCACVKG----------------------------------------------------------------------------------------------------------------------------NPECPVLK--------------------------------------------------------------------------------------------------------HNLEPTENLGS---STRRRGRKDKEPSRDESGQNQNLTMDCDGSKGKTLN-DAKQRKLSPLRLSISN------------------------------------NQDPELIEDLEEKTSVSNEVEMESEEQIAERRRKMGSPAEESHRHDAG-------------------------------------------------------------------------------------------------------ASCCRALRNKETREERKMEAILQAFARMEKREKRREQALERIGTKGEVGGRSDIKEEAPATPEAESPAVIQPLL---------------------------------------------EVVKEEPGLKP--AKVSRNKQRKSFSRNRTHIGQQRRRARTVSTCSDLPPSSPGDTLEPLMAETQDIEMPVAPEADAPPTQPPETSPPHSGSPAPTCRSGQKYPKTKKHLVSEWMGVDKQERVASRTPEPPPERPLRISSDPEVLATQLNSLPGMSCSSHVYSTPKHYVRFSSPFLANRSPSTPGVPTGRRRSREMPETPTSTGSCKKRWLKQALEEEGSTSPGGGRPFLLIPSESPLSPSINGESCSPLPLNGSCSLPELPTPLKKRRLCS-LDPCMSET--STPYGSPCATPTRTESTEAPGTPSLLATPPRPRPEE--------PSTEPSTPLQ--MPNHPLLQESESSMDSSPDGSRRPSTQD-VERPPSLLASPSVRNVSSDTAPQESSKSMGSLSPQPSHTEPQDAAVDEG-----------MEVDAAAAVTSAAGGGGGSEASTSAPETPVSS----YPPWMKSPERGGISFSPVNSNLRDLTPSHTLEMG-AYRP--------DSTSSGPFSEAAPFFSCNEESSGVTFTRSLSG-DGTGEGSTAKNP-QKKKVSLLEYRKRQR--------EARRSGSKGECSSPVSTAPP-----------------------VDVFPVAVEMAVDPPAPAATPTPRTPQP-------------------SEDP---------DAPQGER-DGEGQWTSSTSVEQARERGYHRALLLSDHRKDTD-GGES------------------------------------------EGGDSQ-VKDCSSPKSCKSPS-THAPCSP---------------------AAQAVSRPSKDEDE----------AQTRGPAQPQAVSVQPSSAKTPSSKPAALTPSKLHCGPSGASQSHYAGPS---------LMHSPKAQPQGSPFR---------------GQRAFLTAQPQNQPQPQ-ATSG-----------PATFPQYNPQNAPPPPPPPPPAPPTSAPYFPTQPTAAAAPFPAFK-----PTVASPFPPGSQP-----------------LLQTHHALHYQSSAAPPPPPPPPPPHPQPGPTLLHVNLQPPSLQQHQLLLSSAPP-------------------PPPPPPPQTQSSQQPPPNSGTLLS---------IKQGPHPPLPPPPPAPS-------TNAPPHPFQNISGFQTTLLHQSA-PANPSVTASTYQQTVLPPPPPPPPQQTP--------------------PTQTP------PNPSIPQIAGGNRGPAPSS-------------ASFHTTGYLGTGWH------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB5-1", "uniprot_id": "UPSET_DROME", "id": "Q9VUB5-1", "name": "Histone reader upSET", "aln": "MPMSSHDSVFVEPAVSSSGGGSTSSINRIGVASGPQPPPPHIVIDGSSLSTQAQLRIMQRRMSISTRQILSASQSQSINQSQKYAVRTAAGTGALAAGAASSGSSGQELINPQIYKIVTTDGSTSNVIIDASAAAPPHNSKLLLSNLTVLSKQAPVQGAAGQQQQQLNYLGAKSLPYVSASPAKTQQQPQKFGSISAFKAQHQQQQQHPHATLQKVTLGSRVATRLQSYVPASPSQIMVQPAQPKYVNATATTIGGNAALLKKANQKITVKSVSNMSQQQQQQQQQQQQQLLQAQQLKTFITQQQQQQTYKAGAKAKFVKQTTALSIAALPQQQQQTTYAKQSMVTTSTPAKVTKLNSKYVQQQISLPQGTQLQHKASPNVTGGGYLLQQSQAAVGGTIKFVNSHGTVIQQHPQQQQATKRTHYNSSGSSDNEQHAVANSSLITDDVMIVNGTQMTDELSARILQSMAQKSFSQQQRFHQVPATGSGNMPPPTQIIYSNSTSNGAAASSPGGNASGNMLLAHYQAAGTKPVSSASFITVTGTPPVTVATTPSVSISSHGFASGSAAISSYMSSATAARRQSVSAPSSRAVSLERKQHHQQLQHDVIGGGRKAPTVIEYYNKHGVNSIVGSSNNLAQSNSMSNLAGPRSNSGSGFATTTPTPATPLHLTPVNVPVHVEAAPPSSPALVKGSSQPPAQPQQQQQQAHPLGPNQLNANDEELYIEEVRPVPVLTQDLRLQQLHAIMQDHTYASQQQQQQPQQAAGDTTNPGAAQQVQQPQQWSLGGIGVTVSGSQGTPTAVGGYCSYFGQQIARSQADDDAHSAISSSSRMGLASTDIDPGEETETAPEAEAEDDSVTRCICELTHDDGYMICCDKCSAWQHVDCMGIDRQ-NIPEEYMCELCQPRAVDKARARALQRQKRKEHMLLVATQAANGAAAVAAGTTLSGGLGSGLPMSEELQHRLASGLNGGFATGTGMSKKSKKTKENSGSTSTLKKTKKSAVGMGGEKNASGSGTPTGSSGKTSKKSSKRKSKSGGDGSSGGGSSPALTAAEKHAANLRQWIENYEYAVTNHYSPELRARLHAIQKQ--PSLLQSIQNTENKALRQIQQQLSTAGSAEQLEQRAQLIPYAGAKVLISSVDLSPHAPIHELRGKYMLTTQFRTQNPTVNMNTPPPSNYLNSFKAHKTPGQFVFFYQLPGVEAPMQTLRPDGSVPQVAQQPPSYLKGPEVCVDTRTYGNDARFVRRSCRPNAELQHYFEKGTLHLYIVALTHIRAQTEITIRHEPHDLTAVEQKKSHAAVIQPTSTRCACDMGSDCLFALPLAVQQQLQAPPTQPRSSHRNKAAAAAAAAAAANSAAAIQLTMGLGVGATVAAGASVLPNSRNRSTSSSGESSQMGLNSPQLGQLNLGFKTSVTATSLTAPVPGVHCNNSGGSSSSSNNSCSVSMSSVLHDSGICTSSSSPSVSIPSPTPTQMQSPTLQQHPQQIPQQQLSLLQRSPTQQHQQQILAALPTPMLTPMLSPQLPKPAQQQAHVVLPQSQQTSLLQQQQSQQSQEPLAVIAAAAAAQQPMATYFVRQPQQQQQQQSPKPQALVAQQQHVVGAQQQQHFLQQQQKQQQQQMADEARMAVSALQTLHAAPTSHIVSPIKVAAVQQQSQPQQQQQNTHQQPHNQQAVQQQSNQLQQQQSQQPNYPQSPQRQQKPQPVQHQPQIVISTGAQAIPATMPTKLSSPTKSAAPVISNNNITVSAQSSVVGGKKTPAKHPQQQQQQQQQPVTPVSAATAPAATPSSSESKEDDVSASSTTTPTTRTPAKDKPKQSREDRKLEAILRAIEKMEKQEARGKKDTRQSSGGKRQASNSPASPNKRNSSNSISEDVETPTSTNSAAAAAQRRNKKKRKVSRSLNNNTNGLGSGGGSNNKRRKSIVVESDGESHALTNSESEDQGQHPQSHHSGSEDQAAGLLLALAHNNSSPNEPFKSPLSQSHSLPATPASVSSACLLIEAAMGPLQQQPAPASASPSLAEFKYPPGGAKTKKSLMSSWFQ--QAEQQHASGLDSLVQAAMSEINGEREQLQRQPQGESLPAPALLKVEQFIHQAESTTAVPAR------------EQLHLPLQ--NNSSVKKRWLRQAISEET---------TPVDELQQSQNQSVTATPSPQPVPTVSPLANGFSTPLKKRRLVVVSNGTNVES---DETHIDVIGEPKDEAEENVAMTELKVEIENHHQEQDDDVDILRSPSPGTHQIVAEDNLVKIEPEDTSAAADDVKIDVEREESQACDKFEEMVKVKREEEEQREKEIKQLQERQEHEQPKVEPAPVEPKLENTVAKAEPKVEPSQEIVSKKEPTKVEPKPGESLLRSTATVTATPTAATIAATTLLDVSKVAFKTRPPLKLEDEPQKKKPKLESILPAPVATVPPVSVPPIPAASNATTSAVTNTAAASLTTTTAPSSTKNLTEHDIQERLLSFHAANISYLQSRNKKATAALTSASPSQKSNSSSGGSGTESKKSSKDKDEKRDKEKQLKKSKKEKKKSKDKEKQKAAVNVNSTSQIVDTKKKTTQPSKPDSKSSIAPVLVPPSLPVATANGKTKHTAYNNVDQQQQQQMRRRTMSMCITPVTPTPVVTPSPLHGTPPSTKKRQTNFEQELTKPNSQILSSSILLNSSKGLGLPLAAPTVVSVPTAVQQQQHRKENNHQEATPASGGPMSLAAAIASGKLNAISRRRESMCGSRQQQALIAAALKKEKKEKKK--------SKKKDREKQKHDKQKGKEKEREKDKEKDNKQKTNHIQKPAHPTTVPANSMPISAPAPVPVLVPTPVTTPKAAPIP----------------------------------VLITQPTPSPIHVTQPLVNNCSTKVASLPFYNTIYGKLQDPSTPTSSPIPVTNTMPSLAEYLESTKSKTTALSAVKP------------------IGIAAVTPLSSAITPAKVAPSSLEMPPPATTPLKLYTRTASHDPRLNPMLTVPDPTPMPKRKLSISEYRMRHRPSVDTAPTTPTTPTTPTTPTTPPGSNKDRSFAKPQTINKCSLQSPERFQAAIRERRNSISAHHPQQNAHHNLNNNKGGISNKSGSSSGNHLQQALGVAGGRLQSKNAIVDPAATTLSTVNSILSTAQKLHMFDDKPKGGHFNAAPTLLEQQQEKMSERSRCLQRTISCDSRVIERLGTGAAAGALEKVTTASTRRDAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36124-1", "uniprot_id": "SET3_YEAST", "id": "P36124-1", "name": "Histone reader SET3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPNSKEQSLLDDASTLLLFSKGKK------------------RAEEASK--------------------------------IGSKTDTIEHDESHEREKKGAIEMAAAALAT----------------------ASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQWPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASS-------------------------------------TTISDVGDSFSTDQDNTNHRDKRRKRNPSNNSIDSKNESAS------------VNSSDGLTSMPKKKEHFLSAKDAYGAIYLPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSR---------TYPGFTKLGVYLKKDCIKGDFIQEILGELDFYKNYLTDPR-------------NHYRIWGTAKRRVIFHSH-----------------------------WPIYIDARLSGNSTRYLRRSCQPNVELVTIKLQDTDNRNDKSSGRKSSRIKFVLRALRDISEDE-------------ELYIKWQWD-----------------------------------------------------------------------------------------------------------------------------SKHPILK-----------------------------------------------------------------------------------------------------------------------------------------------LIKGMTIDSLDDLERYGLINSVETILSN-------------------------------------GECGCGNNSKDCYLLKVKRYAQSLYKSVKSRGKMN--------------------------------------------------------------------------------------------------------------------------------NRYKLNEILNQYNCKKRREPPILHRLEEKAQNTIERAPILLNNFYRQKFLNRNNGPKIP----------------------------------------------------QKNTIDSTNNPDDIAKPFKFALFAQHSSNISVPKKNETSEKPLIITKSTDYDESHITNIEELPIPVLLPINKTSRQTANDVEESQSKNEHKLSRTPSLSNFNKELS--------------KEAQHSQAKTKEIMTEASVNSRRESTPESIMHLSDFSSSQLHSKKKLS-----------------------------FADYRKKLLK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : *.. . :*. : . . : . :**: : *::* * :. : .: . :: . : ::. : .:: . .. : * * :. : . . . : . * * *: : :: .: . *:*:. : :*:* **.:*::**** **.*: .. : : :..: . . . .: . : . . : : * : *:. :::: . . . . : . .: :* * : . . .: . . : .. :*: :: ", "identical_positions": 31, "similar_positions": 115, "identity": "0.96%" }, { "cls_id": "homologset.agr.SGD:S000001738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ61-1", "uniprot_id": "UNC50_MOUSE", "id": "Q9CQ61-1", "name": "Protein unc-50 homolog", "aln": "----------MLPSTSLSSSMHGNGVLNS--RDAARH-----TAGAKRYKYLRRLFR-FRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVS-------TIGFGFVLDMGFFETI----KLLLWVVFIDCVGVGLLISTLMWFVSN-KYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILT--DTFIGYLVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLMVLYGLSLALGWNFTHTLCSFYKYRVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55227-1", "uniprot_id": "UNC50_RAT", "id": "O55227-1", "name": "Protein unc-50 homolog", "aln": "----------MLPSTSLNSSMYGNGALNS--RDAARH-----TAGAKRYKYLRRLFR-FRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVS-------TIGFGFVLDMGFFETI----KLLLWVVFIDCVGVGLLISTLMWFISN-KYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILT--DTFIGYLVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVVLLYPFAPLIVLYGLSLALGWNFTHTLCSFYKYRVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53HI1-1", "uniprot_id": "UNC50_HUMAN", "id": "Q53HI1-1", "name": "Protein unc-50 homolog", "aln": "----------MLPSTSVNSLVQGNGVLNS--RDAARH-----TAGAKRYKYLRRLFR-FRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVS-------TIGFGFVLDMGFFETI----KLLLWVVLIDCVGVGLLIATLMWFISN-KYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILT--DTFIGYLVGNTLWLVAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLILLYGLSLALGWNFTHTLCSFYKYRVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUU1-1", "uniprot_id": "UNC50_DANRE", "id": "Q7ZUU1-1", "name": "Protein unc-50 homolog", "aln": "----------MLPTSSPQ--IHRNGSLSE--RDAARH-----TAGAKRYKYLRRLLH-FRQMDFEFAVWQMLYLFTSPQKVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVS-------TVGFGLVLDMGFVETL----TLLLWVVFIDCIGVGLLISTLMWFVTN-KYLMKHPNRDYDVEWGYAFDVHLNAFYPLLVILHFLQLFFINHVVVISSDWFLGYFVGNTMWLIAIGYYVYITFLGYSALPFLKNTVVLLYPFALLGLLYVLSISLGWNFTKGLCWFYKHRVQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHN5-1", "uniprot_id": "UNC50_DROME", "id": "Q9VHN5-1", "name": "Protein unc-50 homolog", "aln": "MTQYSHVKYTQSPTPSVVSGYSSASRLHSPLPPPANHRRDCLSATTKSYKYLRRLLK-FNQMDFEFALWQMLYLFVAPQKVYRNFNYRKQTKSQFARDDPAFLVLLVVCLCVT-------SLGFAYVLGLSFWQSI----SFIFYVVFVDCIFVGIIIASFFWAVTN-RYLRTN-SLEPDIEWGYAFDVHLNAFFPPLMLLHFIQLFFYNWLISQ--TWFISRFLGNTFWLMGMGYYVYITFLGYNCIPHLKNTRIILIALPIIFLLFLVVTIIGWNATISFVNFYKYRVY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36125-1", "uniprot_id": "GMH1_YEAST", "id": "P36125-1", "name": "Protein GMH1", "aln": "------MSYLPTYSNDLPAGPQGQRRRNNGNENDARQG----YGQQSVPMVIRRLFKTPKNLDLETASWEMFHLIFHPRKAYRSIYYQRQTKNQWARDDPSFFIFQIALISLSSIIWSIYNSGFNNDSDMGALSIIGHFFKSLVMMVILDFFIFGFIMATIFYLLLNRSHFKFKSSQNSVVEWAYCFDVHCNSFLIILLCLYFIQFLLLPIINLQN---WISLLIGNSLYCFAIGHYFILTFYGYNQLPFLKNLNFILLPTLGLSIIYLIS-LFGIDLSKKLS-FYNY---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *.: . . :***:: .::*:* * *:*::*: *::.**.: *::***.*:*****:*::: :.:: . ** .:. . : . :. :*::* . .*:::::::: : * :: . . : :**.*.**** *:* *: *:*:*::: : ::. ::**::: ..:*:*. :** **. :*.*** .:* . : ::: : :* : : : **:: ", "identical_positions": 59, "similar_positions": 105, "identity": "20.27%" }, { "cls_id": "homologset.agr.SGD:S000001739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70498-1", "uniprot_id": "PLD2_RAT", "id": "P70498-1", "name": "Phospholipase D2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVTQTDLFPYGDY-LNSSQLH------------------MEPDVVDTLKEGEDP--ADRMHPFLAIYD-LQPLR-AHPLVFAPGVPVIAQVVGTERYTSGSKVGTCT-----------------LYSVRLTHGD----FTWTTKKKFRHFQELHRDLQRHKVLMSL-LNLARFAAAHSPAREA----------------------------------------------------------------------ANENIPSLPRGG--SEGSARHTASKQKYLENYLN-----------------RLLTMSFYRNYHA--MTEFLEVSQLS--FIPDLGSKGLEGVIRKRSGGHR--VPGFTCCGRDQ--------------VCYRWSKRWLVVKDSFLLYMR-PETGAISFVQLFDPGFEVQVGKRSTEARYG-----------------------------------------------------VRIDTSHRSLILKCSSYRQARWWGQEITELAQGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAREEIFITDWWLSPEIYLKRPAH-SDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNIKVMRHPDLVT----LWAHHEKLLVVDQAVAFLGGLDLAYGRWDDVQYRLTDLGD-------------------------------------PSESADSQTPTPGSDP---------------------------------------------------------------------------------------------------------------------AATPDLSHNHFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTIKARYKIPQYPYLLPKSASTANHLP-FIIPGGQC----ATVQVLRSVDRWSAGT-----LESSILNAYLHTIRESQHFLYIENQFFISCSDGR-------TVLNKVGDEIVDRILKAHEQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTHGELGGH--PISELIYIHSKLLIADDRTVIIGSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRGRCFSVILGAN------------------------------------------------------------------------------------------------------------------------------------------------TWPDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLRDPVCDDFF-QLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVESLATVSPS-----------------------------------------------------LAQSELAHIRGHLVHFPLKFLEDES-LLPHWGAKRGMIPLEVWT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97813-1", "uniprot_id": "PLD2_MOUSE", "id": "P97813-1", "name": "Phospholipase D2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVTQKNLFPYGDY-LNSSQLH------------------MEPDEVDTLREGEDP--ADRMHPYLAIYD-LQPLK-AHPLVFAPGVPVIAQVVGTERYTSGSKVGTCT-----------------LYSVRLTHGD----FTWTTKKKFRHFQELHRDLQRHKVLMSL-LPLARFAVTHSPAREA----------------------------------------------------------------------AAEDIPSLPRGG--SEGSARHTASKQKYLENYLN-----------------RLLTMSFYRNYHA--MTEFLEVSQLS--FIPDLGSKGLEGVIRKRSGGHR--VPGFTFCGRDQ--------------VCYRWSKRWLVVKDSFLLYMR-PETGAISFVQLFDPGFEVQVGKRSTETRYG-----------------------------------------------------VRIDTSHRSLILKCSSYRQARWWGQEITELAQGSGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEIYLKRPAH-SDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNIKVMRHPDLVT----LWAHHEKLLVVDQVVAFLGGLDLAFGRWDDVQYRLTDLGD-------------------------------------PSEPVHLQTPTLGSDP---------------------------------------------------------------------------------------------------------------------AATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTTKARYKTPLYPYLLPKSTSTANNLP-FMIPGGQC----ATVQVLRSVDRWSAGT-----LENSILNAYLHTIRESQHFLYIENQFFISCSDGR-------TVLNKVGDEIVDRILKAHEQGQCFRVYLLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGGH--PISELIYIHSKMLIADDRTVIIGSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRKHCFSVILGAN------------------------------------------------------------------------------------------------------------------------------------------------TWPDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLRDPVCDDFF-QLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVESLATVSPS-----------------------------------------------------LAQSELAHIQGHLVHFPLKFLEDES-LLPPLGSKEGMIPLEVWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14939-1", "uniprot_id": "PLD2_HUMAN", "id": "O14939-1", "name": "Phospholipase D2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTATPESLFPTGDE-LDSSQLQ------------------MESDEVDTLKEGEDP--ADRMHPFLAIYE-LQSLK-VHPLVFAPGVPVTAQVVGTERYTSGSKVGTCT-----------------LYSVRLTHGD----FSWTTKKKYRHFQELHRDLLRHKVLMSL-LPLARFAVAYSPARDA----------------------------------------------------------------------GNREMPSLPRAG--PEGSTRHAASKQKYLENYLN-----------------RLLTMSFYRNYHA--MTEFLEVSQLS--FIPDLGRKGLEGMIRKRSGGHR--VPGLTCCGRDQ--------------VCYRWSKRWLVVKDSFLLYMC-LETGAISFVQLFDPGFEVQVGKRSTEARHG-----------------------------------------------------VRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAH-SDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVT----LWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGD-------------------------------------SSESAASQPPTPRPDS---------------------------------------------------------------------------------------------------------------------PATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLP-FTLPGGQC----TTVQVLRSVDRWSAGT-----LENSILNAYLHTIRESQHFLYIENQFFISCSDGR-------TVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGH--PVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGAN------------------------------------------------------------------------------------------------------------------------------------------------TRPDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLRDPICDDFF-QLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPP-----------------------------------------------------LARSELTQVQGHLVHFPLKFLEDES-LLPPLGSKEGMIPLEVWT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z280-1", "uniprot_id": "PLD1_MOUSE", "id": "Q9Z280-1", "name": "Phospholipase D1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKSETRVNTSTLQKIAADMSNLIEN-LDTRELH------------------FEGEEVEYDASPGDPKAQEGCIPFSSIYN-TQGFKEPNIQTYLSGCPIKAQVLEVERFTSTSRVPSIN-----------------LYTIELTHGE----FTWQVKRKFKHFQEFHRELLKYKAFIRIPIPTKRHTFRRQNVKE-----------------------------------------------------------------------EPREMPSLPRSS-ENAIQEEQFFGRRKQLEDYLT-----------------KILKMPMYRNYHA--TTEFLDVSQLS--FIHDLGPKGLEGMIMKRSGGHR--IPGVNCCGHGR--------------ACYRWSKRWLIVKDSFLLYMK-PDSGAIAFVLLVDKEFRVKVGRKETETKYG-----------------------------------------------------LRIDNLSRTLILKCNSYRHARWWGGAIEEFIRKHGADFLKDHRFGSYAALHENTLAKWYVNAKGYFEDIANAMEEASEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSG-------------------------LSLGSLTAASVESMESLSLKDKHEFHKKEPISKIVDETDMKLKGIGKSRKFSKFSLYRQLHRHHLHNADSISSIDSTSSYFSH-------------CRSHQNLIHGLKPHLKLFHPSSESEQGLTRHSTDTGSIRSVQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIGSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQATAHELR-YQVPGAVP----AKVQLLRSAADWSAGIKH---HEESIHAAYIHVIENSKHYIYIENQFFISCADDK-------VVFNKVGDRIAQRILKAHREGQRYRVYIVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGESSILEQLKPELGNKWINYISFCGLRTHAELEGN--LVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARDLRLECFRLVLGYL------------------------------------------------------------------------------------------------------------------------------------------------SDPSE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLQDPVSDKFFKEIWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPILAKEDAL-----------------------------------------------------RAEEELRKIRGFLVQFPLYFLSEEN-LLPSVGTKEAIVPMEVWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70496-1", "uniprot_id": "PLD1_RAT", "id": "P70496-1", "name": "Phospholipase D1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLRSEARVNTSTLQKIAADMSNLIEN-LDTRELH------------------FEGEEVEYDASPGDPTAQEACIPFSSIYN-TQGFKEPNIQIYLSGCPVKAQVLEVERFTSTSRMPSVN-----------------LYTIELTHGE----FTWQVKRKFKHFQEFHRELLKYKAFIRIPIPTKRHTFRRQNVKE-----------------------------------------------------------------------EPREMPSLPRSS-ENAIQEEQFFGRRKQLEDYLT-----------------KILKMPMYRNYHA--TTEFLDVSQLS--FIHDLGPKGLEGMIMKRSGGHR--IPGVNCCGHGR--------------ACYRWSKRWLIVKDSFLLYMK-PDSGAIAFVLLVDKEFRIKVGKKETETKYG-----------------------------------------------------LRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTDFLKDHRFGSYAAVHENILAKWYVNAKGYFEDIANAMEGATEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSG-------------------------QSLGSLTAASVESMESLSLKDKHQSHKNEPVLKSVNDTDMKLKGIGKSRKFSKFSLYRQLHRRNLHNSDSISSVDSASSYFNH-------------YRSHQNLIHGIKPHLKLFRPSSESEQGLTRHSADTGSIRSVQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIGSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQATAHELR-YQVPGAVH----AKAQLLRSAADWSAGIKH---HEESIHAAYTHVIENSKHYIYIENQFFISCADDK-------VVFNKVGNAIAQRILKAHREGQRYRVYIVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGESSILEQLKPELGNKWINYISFCGLRTHAELEGN--LVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFAQGLRLECFRLVLGYL------------------------------------------------------------------------------------------------------------------------------------------------SDPSE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIQDPVSDKFFKEIWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPILAKEDRL-----------------------------------------------------RAEEELRKIRGFLVQFPFYFLSEEN-LLPSVGTKEAIVPMEVWT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13393-1", "uniprot_id": "PLD1_HUMAN", "id": "Q13393-1", "name": "Phospholipase D1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKNEPRVNTSALQKIAADMSNIIEN-LDTRELH------------------FEGEEVDYDVSPSDPKIQEVYIPFSAIYN-TQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSIN-----------------LYTIELTHGE----FKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVRE-----------------------------------------------------------------------EPREMPSLPRSS-ENMIREEQFLGRRKQLEDYLT-----------------KILKMPMYRNYHA--TTEFLDISQLS--FIHDLGPKGIEGMIMKRSGGHR--IPGLNCCGQGR--------------ACYRWSKRWLIVKDSFLLYMK-PDSGAIAFVLLVDKEFKIKVGKKETETKYG-----------------------------------------------------IRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSG-------------------------PSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNH-------------YRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELR-YQVPGSVH----ANVQLLRSAADWSAGIKY---HEESIHAAYVHVIENSRHYIYIENQFFISCADDK-------VVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGN--LVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYL------------------------------------------------------------------------------------------------------------------------------------------------DDPSE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPI-----------------------------------------------------RAEEELKKIRGFLVQFPFYFLSEES-LLPSVGTKEAIVPMEVWT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PGG2-1", "uniprot_id": "A0A8M9PGG2_DANRE", "id": "A0A8M9PGG2-1", "name": "Phospholipase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRPQDP--TVSTLHLVANDMTDIMEN-LDTRELD------------------IGDGEDEFDGQ--DPNSTDSRIPFSAVYK-TKGFKEPGARVFLTALPITAKILEVERFTSAQDRFNITAQRS------VSKVLPAVFKIEMKHGN----FTWMVKRKEKHFMELHRELRAYKTFLRIPLPSRSHTERRQTINRN----------------------------------------------------------------------LERHMPTLPRGGGEELAREEQVSSRKRQLEDYLN-----------------KLLKMPMYRNYHA--TMEFIDVSQLS--FIHDLGPKGLEGMVHKRSGGHR--IPGLNCCGHSK--------------MCYRWSKRWMVAKDSCLLLMK-PDSGAISFVLLVDKEFDIKMDTKDTETKHG-----------------------------------------------------VRIDSLSRTLVLKFTSYRHARWWGQAVDDFVRKYGSNFLKDHRFGSFANEQKNILSKWYVNGKQYMEDVANALEEAEEEIFITDWWLSPEIFLKRPVVEGNRWRLDSILKRQAQKGVRIFVMLYKEVELALGINSEYSKRTLLQLHPNIKVMRHPDHVSSSVYLWAHHEKIVVIDQSVAFVGGIDLAYGRWDDREHRLTDIGSVTRTLPV-------------------------SAENASEASPAMAAPSNGPSAALANGKNVPADTAD---QPKLKGHGKPKK-TRFSIRRHLQKHRPTSGDSVSSVESSE---------------------------------------EKSE-----------ATQDLQADVIGLMGNTRFWHGKDYCNFVHKDWIQLDKPFDDFIDRHITPRMPWHDIASVVHGQAARDVARHFIQRWNFTKIMKPKYRSLSYPYLLPKSHTTANEIK-YQVPGCTQ----TNVQVLRSASDWSAGIKY---HEESIHTAYVNAIEHSQHYIYIENQFFISCADSK-------VVHNRIGDAIAKRIIKAYRDGKKYRVYVVTPLLPGFEGDINTGGGSAIQAVMHFNYRTMIRGDCSIISQLKKEMGDQWINYISFGGLRTHAELEGR--LVTELIYVHSKMLIADDNTVIIGSANINDRSMLGKRDSEVAVIYEDIHTVKSVMDGQEYQAGPFGLSLRLECFRMILGAN------------------------------------------------------------------------------------------------------------------------------------------------TDPSI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVTDPISDQFYKEVWMSTAARNATIYQRVFRCLPSSDVRTILELDSFLSKPGLDKEDPA-----------------------------------------------------RAQEELKKIRGFLVQFPLQFLSEQN-LLPPIGSKEAMVPMEVWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BCW6-1", "uniprot_id": "A0A8M2BCW6_DANRE", "id": "A0A8M2BCW6-1", "name": "Phospholipase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASPESKAAQRWRKCVDS-ITEDQLK------------------SIENNSE-------------KRDFIVVHH-LADLKGGSISPLIYGTPITCKVENTERYTTRSKVHVCT-----------------LYTVRLTHGE----FTWTVKRKYKHFQELHRDLYKHKVMLQF-LPLGRFAIQRQQLAG-----------------------------------------------------------------------LTEEMPTLHGTD-----RIRRTSSKPKYLEEYLN-----------------NLLENTFYKNYHG--MMDFLAISPLS--FIRDLGPKGLEGYILKRSGGHR--IQGLNCIGHHQ--------------FCFRWSRRWLVVKDSFLLYMS-RDPGIVSFVLLFDPELKVLVGRVYTDIQHG-----------------------------------------------------ICIENFDRKLVIKCSSYRQAQWWSHEIRSLSER--CDFYKLHRFEGFAPPRPDTLTKWYVNGHGYFSDLADALEQAKEEIFITDWWLSPEVFLKRPAT-GTYWRLDKILKRKAEQGVKVCVLLYKEVELALGINSGYSKRKLMSLHPNIKVMRHPDHVASVVVLWAHHEKMVAIDQSVAFVGGLDLAFGRWDDSDYRLSDLDSPKQPSP-------------------------------PEAASELPTPSLSQGD-------------------------------------------TVDGSAVPLTQPAS----------------------------------------------------------ECEDEVDLSCNALLWLGKDYSNFIKRDWTQLDQPFQDNVDRTQVPRIPWRDLGAAHHGKAARDLARHFIQRWNFTKIFKNKYKDDFYPYLLPKSHCTSDTLP-FSIPGATK----ASVQVLRSVDRWSAGT-----CEHSILNAYVHVIENSQHYIYLENQFFISCAEEK-------NVQNTIGDAIVKRILRAHSEGKKFRVFVVIPLLPGFEGDISQGGGNAIQAILHFTYRTINRGEHSILSRLKEQMQDKWTQYFSLCGLRTHSQLGSS--PVTELIYVHSKALIADDRCYIIGSANINDRSMLGTRDSELAVLVEDEERISSVMDGEEYQAGPLALALRKECFSVLLGAK------------------------------------------------------------------------------------------------------------------------------------------------SDPSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIDDPISDHFFNDVWNKVAQTNAIIYEKVFRCLPLDSIRNLRELMEHKNSENLSLTDPE-----------------------------------------------------KAREELQAIRGILVHFPLHFLCEEN-LLPPLKSKEGIVPIEVWT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZT5-1", "uniprot_id": "B7YZT5_DROME", "id": "B7YZT5-1", "name": "Phospholipase", "aln": "----------MMATCLDTKTSKNHEAQQLQLPRQASSNANLPHLQVRRHRRSISQLMASMVEHPTDDVYRPAHYGGYVNRGYDDLDSSYYFAQYEAMADAGTVGGALPPYALTNSDEEHGSGEEDASEENSNNEEGEGVFRDCTDEAVVEHHNR-------------CLPEFQFSLVDSEYDETLAFPDSVTILSNVGDKPVLVERKE------------------TDDDEEEFDDEENNSVVLRHEIPFTSIYGPSVKFNSFQRKVFIPGREIHVRIVDTERSVT-THLLNPN-----------------LYTIELTHGP----FKWTIKRRYKHFNSLHQQLSFFRTSLNIPFPSRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSKIAGSNANNAMAMISPNHSSILAGLTPRRIQKKRKKKKKRKLPRFPNRP-ESLVTVENLSVRIKQLEDYLY-----------------NLLNISLYRSHHE--TLNFVEVSNVS--FVPGMGIKGKEGVILKRTGSTRPGQAGCNFFGCFQKNCCVRCNYFCSDVVCGTWRNRWFFVKETCFGYIR-PTDGSIRAVILFDQGFDVSTGIYQTGMRKG-----------------------------------------------------LQVLTNNRHIVLKCWTRRKCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADGLEAALEEIYIADWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYYSKSTLAK-HENIKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLGSISTSSFSGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTSIELKTLKPGDRLLIPSTLVSSPGETPAESGIALEGMKLNTPEMERKNVLDRLKNNAMKGARMGKDFMHRLTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAITTSSTQILSEFCGQAKYWFGKDYSNFILKDWMNLNSPFVDIIDRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKLEKLRDNTR-FPYLMPKSYHQVRLNPNIQQNRQQR----VTCQLLRSVSAWSCGFIEADLVEQSIHDAYIQTITKAQHYVYIENQFFITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVYVIMPLLPGFEGDVGGSTGIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNT--PITELIYVHSKLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPSGVFAGRLRKYLFKEHLGLLE-------------------------------------------------------------------------------------------------------------------------------------------SEGSSRSDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTDFVKTFASLRKYQEEPPLAKTAPD-----------------------------------------------------LAANRANDIQGYLVDLPLEFLNKEV-LTPPGTSKEGLIPTSVWT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36126-1", "uniprot_id": "SPO14_YEAST", "id": "P36126-1", "name": "Phospholipase D1", "aln": "MSNVSTASGTHFAPPQADRSVTEEVDRVNSRPDELENQEVLRQLPENGNLTSSLQREKRRTPNGKEAERKHALPKSFVDRNLSDVSPNHSLDHIMHSNEHDPRRGSDEENMHRLYNNLHSSNNNVHSKRNSKREEERAPQRRSSSVAYTQQQFNGWKKEFGHAFKKISAIGRLKSSVNSPTPAGSGHRHNQHQHQQVNEEDLYTQRLASDLLDSLLAGCPASLFASTQFLRDEHGKRRAPLLLAKLDVRVSPLKNDNNILDITNSNHNHRGNNNNNTGENSDRRPSIPRSSSIISISSNVAEFMYSRNENSLFRIHLEYGIDEDRLKWSIIRSYKDIKSLHHKLKIVAFQQLTISKLYSDNNRYHSLQLPHFPHYKEMVKERNVMEKKAENKPSSAASAPHTSE-------------------------------NNNNDNGSNITSLETLSSSEISEFNIDNVKMKHLQDLIDEPDDFSQPIHLRLERYLRLLNIALCLRPHANRLFEFYELSPLGNLLSRESGFQGKQGYLVIRSTAKAQGWRVSHFGKHAFKD------------MIDRHTTKWFLVRNSYLTYVSDLSSTTPLDVFLIDWKFKVRFSGNKNNILDNENEINWIIHDPNLEINDELEEFGIENDANNILDKNGKSKTHQKKSNISSKLLLLTLENSERKLKIICKSESSLKQWMSSIIKMSTS--TPWSKPNRFGSFAPVRTNSFCKFLVDGRDYFWSLSEALLMAKDVIYIHDWWLSPELYLRRPVKGNQGFRIDRMLKSCAEKGIKIFIVIYRNVGNIVGTDSLWTKHSMLNLHPNIHIIRSPNQWLQNTYFWAHHEKFVVIDETFAFIGGTDLCYGRYDTFEHVLRDDAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLDQNFPGKDYSNARIADFHDLDKPFESMYDRKVIPRMPWHDVQMMTLGEPARDLARHFVQRWNY--LLRAKRPSRLTPLLTPPSDLTAEELKSLPMFEILREKSTCETQILRSAGNWSLGLKET---ECSIQNAYLKLIEQSEHFIYIENQFFITSTVWNG-----TCVLNKIGDALVDRIVKANQEKKPWKAFILIPLMPGFDSPVDTAEASSLRLIMQFQYQSISRGEHSTFSKLKKLNIDP-AQYIQFFSLRKWSTFAPNERLITEQLYVHAKILIADDRRCIIGSANINERSQLGNRDSEVAILIRDTDLIKTKMNGDDYYAGKFPWELRQRLMREHLGCDVDLVEFVEKKFERFEKFAAKNYEKLHTLSKEGDSGNNWSDREMIDSAMIELGYREIFGCKFSPQWKSGHGNSVDDGSTQCGINEKEVGREDENVYEKFFNSVDYGKSSRKRTPLPKHNFASLGLTFNHRAGIENVGIRDHKVLSTDPRLRKNDEHKKEVDGYGPDCWKKESNKKFKADATEQLKEWALNSLASKVLDDKEMIKSEIPEGFSNYLPNEKDLEMYLTDKTVTNRNKWSMLKRICYLQYLSHKLDERKTQRLKKIKDMRRHLSSSTESTRNGSNSLPLNEKSNEGESTNVDQDIEGDEYHRLHEDILKNQELDDGSLDDLLSQIIPKITNFNSGEIDDAKKEELLKLNFIDPYSFEDPLISSFSEGLWFTIALRNTLLYKLVFHCQPDNAVQNWKEYGEFTELEQEFQINQEKLIDLEAENINSTTTNVVDKDREKEKMRKAAELRMKLSGSLLYGFNQKVFDKHTAQRILERIHGHLVIFPTEWLAKEVESRNWIFNSDRLSPMEIYN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : . :* : :: :.: :* :.* : :.: .:*:.* .:. : . : : *:: : .:* .: * :* :* :. : * :* :* : *: . :*:..::: : : * *.* : : . . . : : . * : : : : * : . : : . .:* : . : *:. *: :::.: * : *:* *******::::**. . :*:* :* *::*::: ::::::* :* :* ::* : * **:::* *: :******:: :*: **:** **.:**:* .: * * . : ****.* *: :*: ** . ** **:**:*: * .***:****:**** : : * * * * *:***. ** * * ** ** : * .:.*::*:******: * * :*: : .**::* : ::.::: **:***:. :. . . ::: : :: * :: ** * : :*: :*:.: .**. . : ::* :*:*:* *****. * ******:** :*.****:* : * . *:* .* :* : ** : ** . .. **: . * * : *: :*. :*:* * . :. .. * ::* ** :* :* .: . : * .:: ", "identical_positions": 188, "similar_positions": 239, "identity": "9.82%" }, { "cls_id": "homologset.agr.SGD:S000001742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09100-1", "uniprot_id": "GATA2_MOUSE", "id": "O09100-1", "name": "Endothelial transcription factor GATA-2", "aln": "MEVAPEQPRWMAHP-AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCMQEKSPPF-SAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924Y4-1", "uniprot_id": "GATA2_RAT", "id": "Q924Y4-1", "name": "Endothelial transcription factor GATA-2", "aln": "MEVAPEQPRWMAHP-AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASPSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLAPMGTQPATHHPIPTYPSYVPASAHEYGSGLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCMQEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23769-1", "uniprot_id": "GATA2_HUMAN", "id": "P23769-1", "name": "Endothelial transcription factor GATA-2", "aln": "MEVAPEQPRWMAHP-AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXB8-1", "uniprot_id": "A0A8M3AXB8_DANRE", "id": "A0A8M3AXB8-1", "name": "", "aln": "MEVAADQSRWMAHHHAVLNGQHPESHHHGLTHNYMEPMAPLLPPDEVDVFLNHLDSQGNPYYSN---SRARVSYGQAHARLTGSQVCRPHLIHSPGIPWLDSGKAALSAA---HHNAWAVSHFSKPGLHPASAAYP------------CSSSSSTAPVSSLTSATHSSPHPLYNFPPTPPKDVSPDP---GPSSPTS-----TTARMDEKESIKYQVSIADGMKMEGCSPLRGSLAMSAQTPSTHHPIPTYPTYSLPAPHDYGGGLFHPGTLLSGSASSFTPKCKSKTRSCSEFCTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNGNGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKRSKRSGEGFEELSKCMQDKTSPFGSASALASHMPHMGHLPPFSHSGHMLPTPTPIHP----TFSHPHHSGRSPAWAEPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26343-1", "uniprot_id": "DAL80_YEAST", "id": "P26343-1", "name": "Nitrogen regulatory protein DAL80", "aln": "MVLSDSLKLPSPTLSAAAGVDDCDGEDHPTCQNCFTVKTPLWRRDEHGTVLCNACG--------------------LFLKLHG--EPRPISLKTD-----------------------TIKSRNRKKLN-------------------------NNNVNTNANTHSNDPNKIFKR--------------------------------------------KKRLLTTGG----------GSLPTNNPKVSILEKFMVSGSIKP---LLKPKETVPNTKECSTQRGKFSLDPCEP------------SGKNYLYQINGSDIYTSN---------------IELTR---------------LPNLSTLLEPSPFSDSAVPEIELTWKLHNEEEVIKLKT--------KISELELVTDLYKKHIFQLNEKCKQLEVELHSRASVQSHPQH--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: . . *. . :. :... :* : : * ** ...: : . . :* * ** ::: ::. .: *: * : : : . :: . : . . *:.: :. .: ... . *::* : .. .. * : : . .*. : . *:: :*:. * .* *: .* .. :** . . .*.. * :**** :. :.:*. *:*. . :. : : :*.: :: : * ::: .* ", "identical_positions": 37, "similar_positions": 107, "identity": "7.55%" }, { "cls_id": "homologset.agr.SGD:S000001744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1LXQ1-1", "uniprot_id": "Q1LXQ1_DANRE", "id": "Q1LXQ1-1", "name": "", "aln": "--MGEVR---KLQKKLRQIENLEIKISLTPEEKIKVSKKAELRSRLAELLLQ-------------------------LSGPQQTQGIVGKEEDKMKRQVEEVTEQHV-----GHRPALKIAREERRENEASDGNQTDGRGETNLP----------------VSLTEEEQEDAEFRSRKQTWEKAKFR-------------LRALEGHSDIITCAVAVDN-LVISGSRDTTVKVWHVPTATEQRNLGGHSGGVTCLCAPPPESCRRLARAFDLADKER----FVLSGSTDCCVKIWALSSGQCVKSIYTF----------NAVTSLCFIPEGEGFIVTGSDAGKLQVWSWSSLENWLSVNAHLDAVTTLQSHG---PLVFSGSAEGSVCVWEVCDEGPEPLRRLHLWG---PEVTGCGGEDGLNGRLVLSPRGDRVFLSCGKASIRILNWRTGVMTRLANHSSTAGVTDCVNQIPGLLIASCFDLANGESTINLFSLPQCKYLVSLTSSDLPRILCFAA-----WLTASGD---------HRWVTGGRD--LIVWEQLPGTFKKRGDVTVRRDRRLEDCILESDRDSEDDRSEDDAD-DEDATTQDAPETEEPASSSWLRCVLQ--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36130-1", "uniprot_id": "CAF4_YEAST", "id": "P36130-1", "name": "CCR4-associated factor 4", "aln": "MGSGDTRGESSLVAKPIEIILNKLPHAILAQQQFQKYITSPIYRYLSKLLLFREVAWPESTKDTQKGQVGIFSFQNNYADSATTFRILAHLDEQRYPLPNGAAEKNLPSLFEGFKATVSIIQQRLLLDNVDGATNSDKEKYVQLPDINTGFVNKTYSRIDLTHLLEDVETNVENLSINKTLEMDELTRLDSMINELESRKLKILERVKHIDSKSTNLENDVTLIKDRINFIEEYNLEADREQSLRKQMEEERSSEASSFTQNEEAISSLCDVESKDTRLKDFYKMPHEKSHDKNRQIISETYSRNTTAFRMTIPHGEHGNSITALDFDTPWGTLCSSSYQDRIVKVWDLNHGIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIAYDLPVSSLDFDGKLITVGANEGGVNVFNMERDEHWMTPEPPHSLDGDELSRRIAIVKYKDGFLINGHNDGDINVWTL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.* .* * :* :: :: .::::: .: : *::*** :.. * *:.: ::: : .:*::: *.:.::.* ::. ::.....::* . .:** . * *: : :.* * ::* * :: *: ** ..* : :. ::* :.: .* . :: ::: : ** . :. .:. .:. . :: *: .*: * .. * : * :. :* *::*:* * . : :. : ::**. . : .: .** :*. :* . ::::** :.:: :*:: . * : * ** * : *: : : * * .*. . :*::* . . : : . *.. ::*. : . * . *:.: . *.: *...: *: : . * . * .: ***. * : :*: ..:: . : . * * : .*.. . : : **. * :.*.: : . * .::: ", "identical_positions": 83, "similar_positions": 205, "identity": "12.91%" }, { "cls_id": "homologset.agr.SGD:S000001746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS2-1", "uniprot_id": "OSGEP_RAT", "id": "Q9WVS2-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALTEAGLTPK--DIDCIAYTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDAAQ--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNVRLQEMMATMCQERG-AQLFATDERFCIDNGAMIAQAGWEMFQAG-HRTPLQDSGITQRYRTDEVEVTWRD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWU5-1", "uniprot_id": "OSGEP_MOUSE", "id": "Q8BWU5-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALAEAGLTSK--DIDCIAFTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDAAQ--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNLRLQEMMGTMCQERG-AQLFATDERFCVDNGAMIAQAGWEMFQAG-HRTPLKDSAITQRYRTDEVEVTWRD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPF4-1", "uniprot_id": "OSGEP_HUMAN", "id": "Q9NPF4-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTESGLTSQ--DIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGATSPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDVAH--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSQEALIVGGVGCNVRLQEMMATMCQERG-ARLFATDERFCIDNGAMIAQAGWEMFRAG-HRTPLSDSGVTQRYRTDEVEVTWRD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHZ6-1", "uniprot_id": "OSGEP_DANRE", "id": "Q5RHZ6-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MT--------------IVIGFEGSANKIGIGIIK----------------DGEVLSNPRRTYITPPGQGFLPGETAKHHRSVILTVLQEALDEAGLKAA--DIDCVAYTKGPGMGAPLVTVAIVARTVAQLWGKPLLGVNHCIGHIEMGRLITNAQNPTVLYVSGGNTQVIAYSERRYRIFGETIDIAVGNCLDRFARVIKISNDPSPGYNIEQMAKKG---NKYIELPYTVKGMDVSFSGILSYIEDAAH--------------KMLSTDQCTPEDLCFSLQETVFAMLVEITERAMAHCGSQEVLIVGGVGCNLRLQEMMGVMCKERG-ARIFATDESFCIDNGAMIAQAGWEMFRSG-HVTELPDSWITQRYRTDEVEVTWRD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV41-1", "uniprot_id": "OSGEP_DROME", "id": "Q9VV41-1", "name": "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MV--------------CALGIEGSANKIGIGIIR----------------DGKVLANVRRTYITPPGEGFLPKETAKHHREAILGLVESSLKEAQLKSS--DLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIEMGRLITGAQNPTVLYVSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNIEQLAKSS---NRYIKLPYVVKGMDVSFSGILSYIEDLAEPGKRQNKRK---KPQEEEVNNYSQADLCYSLQETIFAMLVEITERAMAHCGSNEVLIVGGVGCNERLQEMMRIMCEERG-GKLFATDERYCIDNGLMIAHAGAEMFRSG-TRMPFEESYVTQRFRTDEVLVSWRDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36132-1", "uniprot_id": "KAE1_YEAST", "id": "P36132-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQVHATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:*:******:*:*::: :. :*:* * **:*.** **** :**:*** : :::.:* *: :.. *:* :.:******..** .:.*** : **. **:************* ** * .*.************:**::********:***:********* :*:.*:*********:** . :. ::***.*****:*:****: *: *. : : : ***:****.:************** .*::.********* ****** **::*. .::.***: :*:*** ***:** :: * : :: :**::***** .:*** ", "identical_positions": 188, "similar_positions": 92, "identity": "48.58%" }, { "cls_id": "homologset.agr.SGD:S000001747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "--MSGFFTSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTY---SYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "--MSGFLSSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTY---SYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPKLTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMY---SYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWSEHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "--MARGLPST------------ARLARFCQKLNRLKPLE--------ESSTETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRT-GSAYLF---TYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCPASPGPTVKKY-----DSFSD------------------------------HIQLVDAVQASMSE----------PGQLRPALKPFLGFLDGLS-------PGTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPDSQTPVQGPGCTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLQ7-1", "uniprot_id": "CTR4_MOUSE", "id": "Q8BLQ7-1", "name": "Cationic amino acid transporter 4", "aln": "--MARGLPST------------ACLARFCQKLNRLKPLE--------ESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRT-GSAYLF---TYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCLASPGPTAKKY-----DSFSD------------------------------HIQLVGAEQTSMSE----------PGQLRPALKPFLGFLDGCS-------PGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPSSQSPVRESGCTE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "--MARGLPTI------------ASLARLCQKLNRLKPLE--------DSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRT-GSAYLF---TYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLG--HYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS-----------------------------PPSSPGPASPGPLTKQQ-----SSFSD------------------------------HLQLVGTVHASVPE----------PGELKPALRPYLGFLDGYS-------PGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQR----------------------------------ELPGLNSTHYVVFPRGS---------------------------------------LEETVQAMQPPSQAPAQDPGHME---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19145-1", "uniprot_id": "GAP1_YEAST", "id": "P19145-1", "name": "General amino-acid permease GAP1", "aln": "--MSNT----------------SSYEKNNPDNLKHNGITIDSEFLTQEPITIPSNGSAVSIDETGSGSKWQDFKDSFKRVKPIEVDPNLSEAEKVAIITAQTPLKHHLKNRHLQMIAIGGAIGTGLLVGSGTALRTGGPASLLIGWGSTGTMIYAMVMALGELAVIFP--ISGGFTTYATRFIDESFGYANN----FNYMLQWLVVLPLEIVSASITVNFWGTDPKYRDGFVALFWLAIVIINMFGVKGYGEAEFVFSFIKVITVVG--------FIILGIILNCGGGPTGGYIGGKYWHDPGAFAGDTPGAKFKGVCSVFVTAAFSFAGSELVGLAASESVEPRKSVPKAAKQVFWRITLF-YILSLLMIGLLVPYNDKSLIGASSVDAAASPFVIAIKTHGIKG--LPSVVNVVILIAVLSVGNSAIYACSRTMVALAEQRFLP-----------------------------EIFSYVDRKGRPLVGIAVTS-------------------------------------AFGLIAFVAASKKE-----------GEVFNWLLALSGLSSLFT----WGGICICHIRFRKALAAQGRGLDELSFKSPTGVWGSYWGLFMVIIMFIAQFYVAVFPVGDSPS---AEGFFEAYLSFPLVMVMYIGHKIYKRNWKLFIPAEKMDIDTGRREVDLDLLKQEIAEEK----------------------------------AIMATKPRWYRIWNFWC-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : .. :. : . .: : .. . . ::: * . : : *:. : : * :::***. : . : : . : :. : : : :: .:: . . .. .: . .:: : : :. : * :. *: :.:* . . . . . . .. : ::.*. . : * . : . :: ::.: : :. :. : : : :. . *. :. : : *: .:*:*. *: . : : . : . . . :. *: : : . . :: .: : :: : . : . :.: .: : :. : : : . * : :. : : ", "identical_positions": 18, "similar_positions": 157, "identity": "2.16%" }, { "cls_id": "homologset.agr.SGD:S000001752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G604-1", "uniprot_id": "A0A8I6G604_RAT", "id": "A0A8I6G604-1", "name": "", "aln": "MGGRAGGSAGQWVGPRGGLFDEGPAVGKMAAAPRPS-WWQRWRRRAWARDGA--------RLLLFLLLLGSGSGPGPLHVRAGQAV------------EYLKREHSLSKPYQGVGTSSSSLWNLMGNAMVM-TQYIRLTPDM-QSKQGALWNR--VPCFLKDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGP------------------------VFGNMDKFVGLGVFVDTYPNEEKQHEAQKRRYSPGVQRVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNIR-----YDTFLVIRYVKRHLTIMMD---IDGRHEWRDCIEMPG-VRLPR-----GYYFGTSSITGDLS-DNHDVISLKLFELTGVRTPEEE----------------------------------------------------------KLHRDVFLPSVDNLKLP-EMTEPPT-------------------------------------------------------------------------------------------------------------------------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQDHSRKRFY--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59481-1", "uniprot_id": "LMA2L_MOUSE", "id": "P59481-1", "name": "VIP36-like protein", "aln": "----------------------------MAAASRPS-WWQRWRRRAWARDGA--------KLLLFLLLLGSG--PGPRHVRAGQAV------------EYLKREHSLSKPYQGVGTSSSSLWNLMGNAMVM-TQYIRLTPDM-QSKQGALWNR--VPCFLKDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGP------------------------VFGNMDKFVGLGVFVDTYPNEEKQHER-----------VFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNIR-----YDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEMPG-VRLPR-----GYYFGTSSITGDLS-DNHDVISLKLFELTGVRTPEEE----------------------------------------------------------KLHRDVFLPSVDNLKLP-EMTVPPT-------------------------------------------------------------------------------------------------------------------------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQDQSRKRFY--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0V9-1", "uniprot_id": "LMA2L_HUMAN", "id": "Q9H0V9-1", "name": "VIP36-like protein", "aln": "----------------------------MAATLGPLGSWQQWRRCLSARDGS--------RMLLLLLLLGSG--QGPQQVGAGQTF------------EYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVM-TQYIRLTPDM-QSKQGALWNR--VPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGP------------------------VFGNMDKFVGLGVFVDTYPNEEKQQER-----------VFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLH-----YDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEVPG-VRLPR-----GYYFGTSSITGDLS-DNHDVISLKLFELTVERTPEEE----------------------------------------------------------KLHRDVFLPSVDNMKLP-EMTAPLP-------------------------------------------------------------------------------------------------------------------------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBH5-1", "uniprot_id": "LMAN2_MOUSE", "id": "Q9DBH5-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "----------------------------MAAEAWLWRWGWGWGQRCPGRPGLPGPGPSPTTFLHLLLLLGPV----AADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLT-SQYVRLTPDE-RSKEGSIWNH--QPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGP------------------------VFGSKDNFHGLAIFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRD-----HDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDITG-VRLPT-----GYYFGASAGTGDLS-DNHDIISIKLFQLTVERTPEEE----------------------------------------------------------SIDWTKIEPGVNFLKSPKDNVDDPTGNFRNG-------------------------------------------------------------------------------------------------------------------------PLTGWRVFLLLLCALLGVVVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FPK8-1", "uniprot_id": "F7FPK8_RAT", "id": "F7FPK8-1", "name": "", "aln": "----------------------------MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLGLV----AADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLT-SQYVRLTPDE-RSKEGSIWNH--QPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGP------------------------VFGSKDNFHGLAVFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRD-----HDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDVTG-VRLPT-----GYYFGASAGTGDLS-DNHDLISIKLFQLTVERTPEEE----------------------------------------------------------SIDWTKIEPGVNFLKSPKDNVDDPTGNFRGG-------------------------------------------------------------------------------------------------------------------------PLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12907-1", "uniprot_id": "LMAN2_HUMAN", "id": "Q12907-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "----------------------------MAAEGWIWRWGWGR--RCLGRPGLLGPGPGPTTPLFLLLLLGSV----TADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLT-SQYVRLTPDE-RSKEGSIWNH--QPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGP------------------------VFGSKDNFHGLAIFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRD-----HDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDITG-VRLPT-----GYYFGASAGTGDLS-DNHDIISMKLFQLMVEHTPDEE----------------------------------------------------------SIDWTKIEPSVNFLKSPKDNVDDPTGNFRSG-------------------------------------------------------------------------------------------------------------------------PLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCC2-1", "uniprot_id": "Q9VCC2_DROME", "id": "Q9VCC2-1", "name": "L-type lectin-like domain-containing protein", "aln": "----------------------------MTKP---------------TREHC--------SLALLALLVAPF---VVLGEDMPREP------------DYMKREHSLVRPFQGVG-VILPHWDFLGNTMVT-SNYIRLTPDL-QSKSGALWNY--SPVMTRNWEVHVGFKVHGKG-TELFGDGFAIWYTKERMQTGP------------------------VFGSKDHFSGLAIILDTYSNHNGPHNH-----------QHPYLSAMVNNGSWSYDHDRDGTHTQLAGCEVRFRNVE-----YETLVSIRYENDILSVSTD---LENRNEWKNCFVVAN-VELPT-----GYHFGMSATTGDLS-DNHDIHSFKFYDLDLN-VNHDE----------------------------------------------------------IIRRSNIIPNAKTFEPPREHKEDPKP------------------------------------------------------------------------------------------------------------------------------GMSNAKIFFILLFVVVVAAAVAIFAISYFKDR--NARKRFY--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9D0F3-1", "uniprot_id": "LMAN1_MOUSE", "id": "Q9D0F3-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAVSRRRVPQAGA--------RSFFCALLLSFSQFTGSDGTGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPS-ADQIRIAPSL-KSQRGSVWTK--AKAAFENWEVEVTFRVTGRGRIGADG--LAIWYTENQGLDGP------------------------VFGSADTWNGVGIFFDSFDNDGKKNNP--------------AIVVIGNNGQINYDHQNDGATQALASCQRDFRNKP-----YPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVEN-MVIPT-----QGHFGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTAEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVS---------------QQELDTVVKSQQEILRQVNEVKNSMSETVRLVSGIQHPGSAG---VYETTQHFMDIKEHLHVVKRDIDSLAQRSMPSNEKPKCPDLPPFPSCLSTIHFVIFVVVQTVLFVGYIMYRTQQEAAAKKFF--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62902-1", "uniprot_id": "LMAN1_RAT", "id": "Q62902-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAVSRRRGPQAGA--------QSFFCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPS-ADQIRIAPSL-KSQRGSVWTK--TKAAFENWEVEVTFRVTGRGRIGADG--LAIWYTENQGLDGP------------------------VFGSADMWNGVGIFFDSFDNDGKKNNP--------------AIVVVGNNGQINYDHQNDGATQALASCQRDFRNKP-----YPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVEN-MVIPT-----QGHFGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVS---------------QQELDTVVRTQLEILRQVNEMKNSMRETMRLVSGVQHPGSAG---VYETTQHFMDIKEHLHIVKRDIDSLAQRSMSSNEKPKCPDLPAFPSCLSTVHFVIFIVVQTVLFIGYIMYRTQQEAAAKKFF--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49257-1", "uniprot_id": "LMAN1_HUMAN", "id": "P49257-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAGSRQRGLRARV--------RPLFCALLLSLGRFVRGDGVGGDPAVA--------LPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPS-SDQIRVAPSL-KSQRGSVWTK--TKAAFENWEVEVTFRVTGRGRIGADG--LAIWYAENQGLEGP------------------------VFGSADLWNGVGIFFDSFDNDGKKNNP--------------AIVIIGNNGQIHYDHQNDGASQALASCQRDFRNKP-----YPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVEN-MIIPA-----QGHFGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQIT---------------QQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGMQHPGSAGG--VYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVHFIIFVVVQTVLFIGYIMYRSQQEAAAKKFF--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3S9-1", "uniprot_id": "A0AB13A3S9_DANRE", "id": "A0AB13A3S9-1", "name": "", "aln": "---------------------------------------MAVPIAKCLAAYA--------HLLIISVIFPH---LFADSATGD------------LPHRRFEYKYSFKGPHLTQSDGRIPFWIHTGNAIPS-SDQVRITPSL-RSQKGSVWTK--SPVSFEHWEAEVAFRVSGRGRMGADG--LAIWFTAGQGLEGP------------------------VYGAADQWNGVGIFFDSFDNDGKKNNP--------------AVLVVGNNGKLVFDHQNDGTTQALGTCLRDFRNKP-----YPIRTKITYYKQTLSVFINNGFTPDKDDYEFCTKVEN-MIIPG-----TGYFGISAATGGLA-DDHDVLSFLLFRLTEPGQNLPPPEKEIPKEEKDKYQEEFENFQQALDKRKEEFQKEHPDVQGQPIEDLYESVNDREIRQVFEGQNRIHLEIKQLNRQLAMILDEQRRYVSVITDEINKRTS--QAQSGQAP---------------SHELETIITTQHEVLKNINEVRNSLSGSLKQLAMGQHQGNAGGLGSYETVQHFNDIKEHLHVVKRNIEHIIQKNANPAEKLKCPELPPLPTCLSTTHFLIFIVIQSLLFFGYIMYKSQQEAAAKKFF--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VCD3-1", "uniprot_id": "LMA1L_MOUSE", "id": "Q8VCD3-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MLEIRGL--------SPSLCLLSLLLVLHGAERSQPPP--------------RRRFEYKLSFKGPRLAVPGAGIPFWSHHGDAILG-LEEVRLVPSM-KNRSGAVWSN--ISVSFPSWEVEMQMRVTGPGRRGAQG--VAMWYTKDRAQVGS------------------------VVEELASWDGIGIYFDSSTSD-VQDSP--------------VIRVLASDGHDLQEQSGDGNVRELGSCHRDFRNRP-----FPFRARVTYWRQRLRVSLSGGLTP-KDPEEVCVDVEP-LFLAP-----GGFFGVSAATGTLAADDHDVLSFLTFSLREPGPEETP--QPFMEKDQLLLARKLEELKARLALGTREASIPPLNPKAQEEGERFFNLEDT-----LGRQSQILQALQALSRQMAQAEKHWKQQLGSTVQVRPEGGWN------------------------TAKVSTLLYGQRTLIQALQEMREAAARMASGAHVFYLP--------VGTKHHFFELDHILSLLQKDLRGLVKKTAKAPRPSGW--LLGSSTCLHTSIFLFFLLLQTVGFFCYVNFSRQELDKRLQEYLSTGSLSLEPALPITRTIGVLRRQPISPSMQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FB95-1", "uniprot_id": "LMA1L_RAT", "id": "Q5FB95-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MLKTGGL--------SPSLCLLSLLLALHSAERSYPPP--------------QRRFEYKLSFKGPRLAVPGAGIPFWSHHGDAIPG-LEEVRLVPSM-KNRSGAVWSE--ISVSFPSWEVEMQMRVTGPGRRGALG--VAMWYTKDRDQVGS------------------------VVEGLASWDGIGIYFDSSSND-VQNGP--------------AIRVLASDGHDLQEQFGDGTVRELGSCLRDFRNRP-----HPFRARITYWRQRLRVSLSGGLTP-NDPEEVCVDVEP-LLLAP-----GGFFGVSAATSTLA-DDHDVLSFLTFSLRDPGSEEAL--QPFTEKEQFHLARKLEELKARLALGTREDTILPLNSKAQEEGERFFNLEDT-----LSRQSQILQALQALSRQMDQAEKQWKQQLGSVVQIRPEGGWN------------------------TAKVSTLLYGQRTLIQALQEMREAAAQMASGAQVFYLP--------VGTKHHFFELDQTLGLLQKDLRDLVKMTAKPPRPSGW--LPGFSTCLRTSIFLFFLLIQTVGFFCYMNF-RQELDKRLQEYLFTESISLQPALPIPRTIGVLRRQPVSPSMQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HAT1-1", "uniprot_id": "LMA1L_HUMAN", "id": "Q9HAT1-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MPAVSGP--------GPLFCLLLLLLDPHSPETGCPP---------------LRRFEYKLSFKGPRLALPGAGIPFWSHHGDAILG-LEEVRLTPSM-RNRSGAVWSR--ASVPFSAWEVEVQMRVTGLGRRGAQG--MAVWYTRGRGHVGS------------------------VLGGLASWDGIGIFFDSPAED-TQDSP--------------AIRVLASDGHIPSEQPGDGASQGLGSCHWDFRNRP-----HPFRARITYWGQRLRMSLNSGLTP-SDPGEFCVDVGP-LLLVP-----GGFFGVSAATGTLA-DDHDVLSFLTFSLSEPSPEVPP--QPFLEMQQLRLARQLEGLWARLGLGTREDVTPKSDSEAQGEGERLFDLEET-----LGRHRRILQALRGLSKQLAQAERQWKKQLGPPGQARPDGGWALDASCQIPSTPGRGGHLSMSLNKDSAKVGALLHGQWTLLQALQEMRDAAVRMAAEAQVSYLP--------VGIEHHFLELDHILGLLQEELRGPAKAAAKAPRPPGQ--PPRASSCLQPGIFLFYLLIQTVGFFGYVHF-RQELNKSLQECLSTGSLPLGPAPHTPRALGILRRQPLPASMPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36137-1", "uniprot_id": "UIP5_YEAST", "id": "P36137-1", "name": "Protein UIP5", "aln": "-------------------------------------------MSRDVRAEKLAISLLILSLFLIFQLVAEIYLNNGDQYHTETSPFTRG------RSHVTRVPNHDASLSIPFLDKINQFWHVGGATQIRNIQSIKLTQDRDQDKHGLVLSNGIGDNTINDFEIVFTFRISHDPTTQLTGDGMCFAITPENGFLTQNLQSSYAKKQYMMNSQGVIADNTDLMGFPKNLPGLFIVLDTYRNQGHDHKEVP--------FMDVFINVAPESDWYDINSDGELSTSLRLNSRGHIKLKKNALWNRVTKLRIIYLESISFLKIDVQYAKEGNYWIELFQTTENLYLPKNMHTGQRYIGCSALNGQLT-ETVELLDVSTSEFHWNDMDASIEDTYDYAKEAELFLEQEFG-------------------------------------EVLDREPDEFTKWKMIKAQPNIKTGSQSAEQKTSN-----------------------------------------------------------------------------------------------------------------------NPHSRLFKVVLTIWHYSEILLLIMGIYLFSACIRVFQRRFKKIRSRRKRAGSHSVGLLPM-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * * : : :::. . :.: * : . :* . ::: * ... : . : *: : .*: .. . : ... : : . .: : * : . . : : .:* *: .. *: : :: .. : :. . .. : : ", "identical_positions": 11, "similar_positions": 66, "identity": "1.64%" }, { "cls_id": "homologset.agr.SGD:S000001756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51860-1", "uniprot_id": "NP1L2_MOUSE", "id": "P51860-1", "name": "Nucleosome assembly protein 1-like 2", "aln": "---MAESVDHKELSESNQEELGSQVMAEGPGESQDRSEGVSIEPGDGGQHGEETVAAGVGE---------------------EGK-GEEAAAGSGEDAGKCGGTDEDSDSDRPKGLIGYLLDTDFVESLPVKVKCRVLALKKLQTRAAHLESKFLREFHDIERKFAEMYQPLLEKRRQIINAVYEP-TEEECEYKSDCEDYFEEE-----------------------------------MDEEEETNGNEDGMVHEYVDEDDG-------------------------------YEDCYYDYD-DEEEEEEEDDSAGATGGEEV--------------------------------------NEEDPKGIPDFWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKLSDPGEP-LSFTLEFHFKPNEYFKNE--LLTKTYVLKSKLACYDPHPYRGTAIEYATGCDIDWNEGKNVTLRTIKKKQRHRVWG-TVRTVTEDFPKDSFFNFFSPHGISLNGG----DEND------DFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDEIYDKIIYDDWMAAIEEVKACCKNLEALVEDIDR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULW6-1", "uniprot_id": "NP1L2_HUMAN", "id": "Q9ULW6-1", "name": "Nucleosome assembly protein 1-like 2", "aln": "---MAESENRKELSESSQEEAGNQIMVEGLGEHLERGEDAAAGLGDDGKCGEE-AAAGLGE---------------------EGENGEDTAAGSGEDGKKGGDTDEDSEADRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQTRAANLESKFLREFHDIERKFAEMYQPLLEKRRQIINAIYEP-TEEECEYKSDSEDCDDEE-----------------------------------MCH-EEMYGNEEGMVHEYVDEDDG-------------------------------YEDYYYDYAVEEEEEEEEEDDIEATGEENK--------------------------------------EEEDPKGIPDFWLTVLKNVDTLTPLIKKYDEPILKLLTDIKVKLSDPGEP-LSFTLEFHFKPNEYFKNE--LLTKTYVLKSKLAYYDPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWG-TIRTVTEDFPKDSFFNFFSPHGITSNGR----DGND------DFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDNWMAAIEEVKACCKNLEALVEDIDR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q78ZA7-1", "uniprot_id": "NP1L4_MOUSE", "id": "Q78ZA7-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "---MAENSLSDGGPAD-----------------------------SVEAAKNASNTEKLTD---------------------QVMQNPQVLAALQER--------LDNVSHTP---------SSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEP-TDAESAWHSE---------------------------------------------NEEEDKLAGDMKNKVVIAE--------------------------------------------KEAATVEEL----------------------------------------------------NPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNP--VLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRG-TVRTITKQVPNESFFNFFSPLKASGDGES--LDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIE-DDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2Z3-1", "uniprot_id": "NP1L4_RAT", "id": "Q5U2Z3-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "---MAENSLSDGGPAD-----------------------------SVEAAKNASNTEKLTD---------------------QVMQNPQVLAALQER--------LDNVSHTP---------SSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEP-TDAESAWHSE---------------------------------------------NEEDDKLAGDMKNKVVIAE--------------------------------------------KEAAAVEEL----------------------------------------------------NPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNP--VLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRG-TVRTITKQVPNESFFNFFSPLKASGDGES--LDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIE-DDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKKEPIQPAECKQQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99733-1", "uniprot_id": "NP1L4_HUMAN", "id": "Q99733-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "---MADHSFSDGVPSD-----------------------------SVEAAKNASNTEKLTD---------------------QVMQNPRVLAALQER--------LDNVPHTP---------SSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEP-TDAESEWHSE---------------------------------------------NEEEEKLAGDMKSKVVVTE--------------------------------------------KAAATAEEP----------------------------------------------------DPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNS--VLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRG-TVRTITKQVPNESFFNFFNPLKASGDGES--LDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIE-DDDNFEEGEEGEEEELEGDEEGEDEDDAEINPKV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FZ21-1", "uniprot_id": "A0AC58FZ21_DANRE", "id": "A0AC58FZ21-1", "name": "", "aln": "----MTLSITAEYLSC-----------------------------SIKMEADNEAKGKVSD---------------------QAMQNPQALAALQDK--------LDSVSHS----------ASIMDSLPKSVKRRVNALRNLQVNSTHIEAKFYKEVHELERKYSALYQPLFDKRRKVVSGEVEP-TDEECEWQSD---------------------------------------------HEDEAALAEDLKKKAAIEE--------------------------------------------KTEDANEE-----------------------------------------------------KPKGIPEFWLTIFRSVDMLSDMLQEHDEPILKHLHDIKVIFSGPDQP-MSFTLEFHFEPNEYFTNT--VLTKVYKMKSEPDADDPFSFEGPEIIDCEGCEIDWQKGKDVTVKTIKKKQKHKGRG-TARVITKQVPNDSFFNFFNPIKVSPDKE---LDEDSEYTLATDFEIGHFFRERIVPRAVLYFTGEALE-DDESFEEEELDEGEEEDQDDEEEEEEEEEGDSKTGDPQPAECKQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28656-1", "uniprot_id": "NP1L1_MOUSE", "id": "P28656-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "---MADIDNKEQSELD------------------QDLEDVEEVEEEETGEETKIKARQLTV---------------------QMMQNPQILAALQER--------LDGLVDTP---------TGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEP-TEEECEWKPD---------------------------------------------EEDE--VSEELKEKAKIED--------------------------------------------EKKDEEKE-----------------------------------------------------DPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFVLEFHFEPNDYFTNE--VLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRG-TVRTVTKTVSNDSFFNFFAPPEVPENGD---LDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIE-DDDDDYDEEGEEA-DEEGEEEGDEENDPDYDPKKDQNP-AECKQQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2G8-1", "uniprot_id": "NP1L1_RAT", "id": "Q9Z2G8-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "---MADIDNKEQSELD------------------QDLEDVEEVEEEETGEETKIKARQLTV---------------------QMMQNPQILAALQER--------LDGLVDTP---------TGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEP-TEEECEWKPD---------------------------------------------EEDE--VSEELKEKAKIED--------------------------------------------EKKDEEKE-----------------------------------------------------DPKGIPEFWLTVFKN-DLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFILEFHFEPNEYFTNE--VLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRG-TVRTVTKTVSKTSFFNFFAPPEVPENGD---LDDDXEAILAADFEIGHFLRERIIPRSVLYFTGEAIE-DDDDDYDEEGEEA-DEEGEEEGDEENDPDYDPKKDQNP-AECKQQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55209-1", "uniprot_id": "NP1L1_HUMAN", "id": "P55209-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "---MADIDNKEQSELD------------------QDLDDVEEVEEEETGEETKLKARQLTV---------------------QMMQNPQILAALQER--------LDGLVETP---------TGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEP-TEEECEWKPD---------------------------------------------EEDE--ISEELKEKAKIED--------------------------------------------EKKDEEKE-----------------------------------------------------DPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFVLEFHFEPNEYFTNE--VLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRG-TVRTVTKTVSNDSFFNFFAPPEVPESGD---LDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIE-DDDDDYDEEGEEA-DEEGEEEGDEENDPDYDPKKDQNP-AECKQQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4AEJ0-1", "uniprot_id": "D4AEJ0_RAT", "id": "D4AEJ0-1", "name": "", "aln": "---MADIDNKKESELD------------------QDLEDVEKVEEEETGEETKVKARQLTV---------------------QMMQNPQILAALQAR--------LGSRVDTP---------TGYTESLPKVVKRRVNALKNLLVKCAQIEAKFDEDVHDLERKYAVLCQPLFDKRFEIINAIYEP-TEEECEWKPD---------------------------------------------EEDE--VSEELKEKAMIED--------------------------------------------EKKDEEKE-----------------------------------------------------DPKGIPEFWLTDFKNVDLLSDMVQEHDEPILKPLKDTKVKFSDPGQP-ISFILEFHFEPNEYFTNE--MLTKTYRMRSEPDDSDPLSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGHGGTVRTVTKTVSNDSFFNFFAPPEIPENGD---LDDDAEAILAADFEIGHFLCEHIIPRSVLFFTGEDIE-DDGDDYDEEGEDA-DEG--------YQLFEQVKSCSKL-FQCWLQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BJ06-1", "uniprot_id": "A0A8M2BJ06_DANRE", "id": "A0A8M2BJ06-1", "name": "", "aln": "---MADLDNKDQAEMDP-----------------ADMEDVEE-EEEDAGED-NSKARQLTR---------------------QMMQNPQILAALQER--------LDGLVGSP---------SGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSEIVRAAYEP-TDEECEWKQD---------------------------------------------EEEE--LTEEMKEKAKVEE--------------------------------------------EKKDEEKE-----------------------------------------------------DPKGIPEFWLTVFKNVDLLSEMLQEHDEPILKHLQDIKVKFSDAGQP-MSFTLEFHFEPNDFFTQT--ILTKTYKMRSEPDESDPFSFDGPEIMGCTGCTIDWTKGKNVTLKTIKKKQKHKGRG-TVRTVTKTVPNDSFFNFFSPPEVPESGE---LDEDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIE-DDDDDYDEEGEEADDEEGEEEADEENDPDYEPKKDANPPEECKQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q794H2-1", "uniprot_id": "NP1L3_MOUSE", "id": "Q794H2-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "---MAEADPKMVTEPGAHG---------------VAEEAMASTACDSGDESDSNSSSSTNSCSSSGSSSSGSSSSSSSSSSSSSSSSSSSSGSSGSSSNGSHLNRKKRVPEPSRRAQRRPSGKLFLDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEP-TEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETPEVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQP-TEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDP-KGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQP-IGYTFEFHFLPNPYFRNE--LLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRRGKDVTVTTT--RSRPGITG-EIEVQPRVVPNASFFNFFSPPEIPLIGK---LEPREDAILDEDFEIGQILHDNVILKSIYYFTGEIND-PYYHDFRDYGNRKYYK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924R9-1", "uniprot_id": "NP1L3_RAT", "id": "Q924R9-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "---MAEADPKMVTEPAAQG---------------VAEEAMASSACDSGDESDSNSSSSTTSCGSTGSSS--------SSSSSSSSSSSSSSGSSGSSSNGSHLHQKKRVPGPSRRAQRRPSGKLFMDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEP-TEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEEIGKENTEVKEEVKDVPEEVPEAKVEEEEAPKETSEVKTEEKEIPKEGPEEKAEEQESSKEFPEVKVEEKTDSTDCIDIAPEEKEDLKDVTQANAEYTDQP-TEDSTPRAPVREAQKRVPETRPEERVNIKRARKGKPKKEDPPRGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQP-ISYTFEFHFLPNPYFRNE--LLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRRGKDVTVTT---RSRPAITG-EIEVQPRVVPNASFFNFFSPPEIPLIGK---LEPKEDAILDEDFEIGQILHDNVILKSIYYFTGEIND-PYYHDFRDYGNRKYYK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99457-1", "uniprot_id": "NP1L3_HUMAN", "id": "Q99457-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "---MAEADFKMVSEPVAHG---------------VAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSST-----------SGSSSGSGSSSSSSGSTSSRSRLYRKKRVPEPSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKPLYDRRFQIINAEYEP-TEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEEN---------------PKENPEVKAEEKEVPKEIPEVKDEEKEVP--------------KEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDP-KGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKPGQP-VSYTFEFHFLPNPYFRNE--VLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRRGKDVTVTTT--QSRTTATG-EIEIQPRVVPNASFFNFFSPPEIPMIGK---LEPREDAILDEDFEIGQILHDNVILKSIYYYTGEVNG-TYYQFGKHYGNKKYRK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1G7-1", "uniprot_id": "Q9W1G7_DROME", "id": "Q9W1G7-1", "name": "", "aln": "---MDAPAEGHVDPES---------------------------CNEIEDE-------------------------------KSGSDCQSMPAYMNSV--------MRRQYLQ-----------QMVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDP-AEEKPQWKE------------------------------------------------PESSTDNEADAEHFREAL-------------------------------------------SSLKSIPK-----------------------------------------------------DAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNG----HSYTLEFHFDKNEYFSNS--VLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEKKMNLTVKTIRKKQKHKERG-AVRTIVKQVPTDSFFNFFSPPEVPSDQEE--VDDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSPNDCPNQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KW25-1", "uniprot_id": "Q7KW25_DROME", "id": "Q7KW25-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "MIGMADSAEGVTQEDS---------------------------HTESRADGISGSLRSLGTY------------------TQESTEPALSPADLPAR--------SRKAFLR-----------HMIGQLAEPVQNRIRALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDILEGSVEPPIQTEKTWPED----------------------------------------------PQDALYLDFGNNEELRQLR-------------------------------------------QKLAPVSP-----------------------------------------------------TTLGVPRFWLTVFQNVPLLSELVQDHDEPLLESLMDVRLAYDQ-----DSYMVIFQFRPNSFLHDSSLLLTKRYFLQHSADPEYPFLFEGPEIVRCEGCHIHWRDGSNLTLQTVESRRRNR-----AHRVTKVMPRESFFRFFAPPQA-LDLSL--ADEKTKLILGNDFEVGFLLRTQIVPKAVLFYTGDLVDSLS-----------------AASPDSRSLSSEAEQEQVL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAZ1-1", "uniprot_id": "Q9VAZ1_DROME", "id": "Q9VAZ1-1", "name": "", "aln": "---METVRNRN-----------------------------------------------------------------------PPRMKYTAPPKMESD-----------------------------LNFTEKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILDEFRKQ----------------------------------------------------------------NHGDVETN--------------------------------------------------------------------------------------------------------------QSVPNFWLRVLKA--SYTEFISKRDEKILECLSDIRSRLYN-EPV-VKFDIEFHFDPNDYFTNT--VLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQTKDQTKTEN--------------------QEPSFFEFFSPPLLPEDTLDP-NYCDVNAMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQSSSGSETESEDTEDESDAEEEDGVDK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25293-1", "uniprot_id": "NAP1_YEAST", "id": "P25293-1", "name": "Nucleosome assembly protein", "aln": "---MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEED---------------------ILANQPLLLQSIQDR--------LGSLVGQD---------SGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVES-----------------------------------------LNETELLVDEEEKAQNDSEEE--------------------------------------------------------------------------------------------------------QVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTND--ILCKTYFYQKELGYSGDFIYD-----HAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : *: . .:. : ...:*.:: : : * .: . . .:* :*: :. : * :. * * . *. * :: : :* * * . . ** * * . . ***.** * *: :* : :: ::: :::* ", "identical_positions": 26, "similar_positions": 54, "identity": "4.26%" }, { "cls_id": "homologset.agr.SGD:S000001759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810F5-1", "uniprot_id": "T184C_RAT", "id": "Q810F5-1", "name": "Transmembrane protein 184C", "aln": "-------MPCACNRNNWRKWIR---------PLLILLYALAILVTVPVCIWEFQKLKVGIHTKVWFIAGIFLLLTIPVSMCGILQHLVHYTQPELQKPIIRILWMVPIYSLDSWVALKYP---KIAIYVDTWRECYEAYVIYNFMIFLTNYLTIRFPNLMLHLEAKDQQNH---LPPLCCCPPWAMGEMLLFRCKLGVLQYTVVRPITTVTSLVCEILGVYDEGNFSFSNAWTYLVILNNLSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVLIALLVKVGVISEKRTWEWQSAEA--VATGLQDFIICIEMFFAAIAHHYTFSYKPYVHEAE------EGPCFDSFLAMWDVSDIREDISEQVRRVG----RTMRG---------YPKK--------------KCFPGDP--------DHNEHSSLLSASSQD-----SSKPSS--------------PVGLYQGFG-------QTITSQSPISIAN-LYEEILNEIPEEQQRLYS-GQDITMDIPEEQPR-HDTGQDVVH-LPYRQELPYKNHYQDHIQTVTSRYLLSSPKPSDDIVIDFSDS--------PEGSDSSTDS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TPR7-1", "uniprot_id": "T184C_MOUSE", "id": "Q3TPR7-1", "name": "Transmembrane protein 184C", "aln": "-------MPCACNRSNWRRWIR---------PLLVLFYATTILVAVPICIWKFQKMKVGMHTKSWFIAGIFLLLTIPVSLWGILQHLVHYTQPELQKPIIRILWMVPIYSVDSWVALVYP---KIAIYVDTWRECYEAYVIYNFMIFLTNYLTIRFPNLILHLEAKDQQNH---ILPLCCCPPWAMGEMLLFRCKLGVLQYTVVRPITTVTALVCEILDVYDEGNFGFSNAWTYLVILNNLSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVLIALLVKLGVISEKRTWEWQSAEA--VATGLQDFIICIEMFFAAIAHHYTFSYKPYVHEAE------EGSCFDSFLAMWDVSDIRDDISEQVRRVG----RTMRG---------YPKK--------------KCFPGDP--------DHNEHSSLLSSSSQDLT-SGSSKVPS--------------PGGLYQGFG-------HTISSQSPISIAS-IYEEIMNDIPEEQQKLLNPGQDVTINIPEEQQKLIDKRKDVMIDIPEQNAIPDNSQYQDQEQIVTLQALFPSTETSENSMIDTSESQQESSDLCTESSDSSTESSDLSTDP------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVA4-1", "uniprot_id": "T184C_HUMAN", "id": "Q9NVA4-1", "name": "Transmembrane protein 184C", "aln": "-------MPCTCTWRNWRQWIR---------PLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYP---GIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKH---FPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEA--VATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAE------EGSCFDSFLAMWDVSDIRDDISEQVRHVG----RTVRG---------HPRK--------------KLFPEDQ--------DQNEHTSLLSSSSQDAISIASSMPPS--------------PMGHYQGFG-------HTVTPQTTPTTAK-ISDEILSDTIGEKK---------------------------------------------------------------------------------EPSDKSVDS-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PD30-1", "uniprot_id": "M9PD30_DROME", "id": "M9PD30-1", "name": "Transmembrane protein 184C", "aln": "----MCSLDVRRFFEEWRIWIR---------PLLIITYVIFAIIVVPLLIVNSVKDGFQRNDQLILIGGLFVLSAVPVSIWHIIQHVIHFTKPILQKHIIRILWMVPIYALNAWIGLFFP---KHSIYVDSLRECYEAYVIYNFMVYLLNYLNLGMD-LEATMEYKPQVPH---FFPLCCMRPWVMGREFIHNCKHGILQYTVVRPITTFISVICELCGVYGEGEFAGNVAFPYIVVVNNISQFVAMYCLVLFYRANKEDLKPMKPIPKFLCIKAVVFFSFFQGVLLNVLVYYNIIKDIFGSDVGDTN---LASLLQNFLICIEMFIAAVAHIYSFPHHPFHINSPQYWNNPNHSWCRAFLSMMDISDMQEDVTEHLGVVGSSLSRRFQGRSTYQPLARSPRRSSSESEYLISKRQDQQLPGNSSQSAGVADDGNSSNSNYQQQQLHLPGAAGSQPSTRQRDTLHLRERERDPGAGAGGGGSFLRLPPGAASAAAPIPESNDDYALLLGAGAGRXHRYQQYHYQQHQHPHIDDAFEDEDGVDVSQQLNASSLSASLSVSFGMSSSLKFSATGSNQSASEWSNSTGGDNDADDGDLDVDGEDGDAEDDGAGVQPVVFIASTTRRRRDREYIT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BG09-1", "uniprot_id": "T184B_MOUSE", "id": "Q8BG09-1", "name": "Transmembrane protein 184B", "aln": "-------MTVRGAALAPD-------PASP----TTTTASPSVSATPEGSPTAMEHPVFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSRPNEQRHIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESAIMSEIRGKAIESSC---MYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAVSTVILQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKINSAR-VSVGEGTVAAGYQDFIICVEMFFAALALRHAFTYKVYADKRL-----------DAQGRCAPMKSISSSLKETMNPHD-----------------------------------------------------IVQDAIHNFSPAYQQYTQQSTLEP---------------GPTWRGG-------THSLSRSHSLSGARDNEKTLLLSSDDEF--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V924-1", "uniprot_id": "G3V924_RAT", "id": "G3V924-1", "name": "", "aln": "-------MTVRGAALAPD-------PASP----TTTAASPSVSATPEGSPTAMEHPVFLMTTAAQATSGFFVWTALLITCHQIYMHLRCYSRPNEQRHIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESAIMSEIRGKAIESSC---MYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAVSTVILQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKINSAR-VSVGEGTVAAGYQDFIICIEMFFAALALRHAFTYKVYADKRL-----------DAQGRCAPMKSISSSLKETMNPHD-----------------------------------------------------IVQDAIHNFSPAYQQYTQQSTLEP---------------GPTWRGG-------THSLSRSHSLSGARDNEKTLLLSSDDEF--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y519-1", "uniprot_id": "T184B_HUMAN", "id": "Q9Y519-1", "name": "Transmembrane protein 184B", "aln": "-------MTVRGDVLAPD-------PASP----TTAAASPSVSVIPEGSPTAMEQPVFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEALVIYNFLSLCYEYLGGESSIMSEIRGKPIESSC---MYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSAR-VSVGEGTVAAGYQDFIICVEMFFAALALRHAFTYKVYADKRL-----------DAQGRCAPMKSISSSLKETMNPHD-----------------------------------------------------IVQDAIHNFSPAYQQYTQQSTLEP---------------GPTWRGG-------AHGLSRSHSLSGARDNEKTLLLSSDDEF--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSM8-1", "uniprot_id": "F1QSM8_DANRE", "id": "F1QSM8-1", "name": "", "aln": "-----MLLLLRRDVPLADHFGEEIVSMAPGLLATMAPDGPNISWLPDAPLLTPEQPIFLMTTTAQAVSGFFVWTALLLTCHQIYMHLRYYSSPKEQRHIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFDTVRDCYEAFVIYNFLSLCYEYLGGESAIMAEIRGKPIESSC---IYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAIITVILQAFGKYRDGDFNVASGYLYVTIIYNISVSLSLYALFLFYFSTRDLLSPYRPMLKFFMVKSVIFLSFWQGMLLAILEKCGAIPQISSPE-VSVGEGTVAAGYQNFIICIEMFFAALALRHAFTYTVYMDKRL-----------DSLGRCAPMKSISSSLKETMNPGD-----------------------------------------------------MVQDAIHNFSPAYQQYTQQSTLEQ---------------GVTAP-----------PLSRNHSCLNARDNEKTLLLSSDDEF--------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UFJ6-1", "uniprot_id": "T184A_MOUSE", "id": "Q3UFJ6-1", "name": "Transmembrane protein 184A", "aln": "MRNASGFLKTAGAPLVSATWL----PPSPPPAMPTVAAGPQMERVDNGSQGAP--QLFLTSALARGVSGVFVWTALLLTGHQIYSHLRSYTAPREQRFVIRLLFIVPIYAFDSWLSLLLLGGHPYYVYFDSVRDCYEAFVIYSFLTLCFQYLGGESAIMAEIRGKPIRSSC---FYGTCCLRGMSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASVSLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIPEVQAVDGTRVGAGTLAAGYQNFLICVEMLFASLALRYAFPSQVYSEKK------------NSPVPPAPMQSISSGLKETISPQD-----------------------------------------------------IVQDAIHNFSPAYQQYTQQSTHEA---------------PGPGQGGHPAPSTHPGPASGSGGGKKSRNIEKRMLIPSEDL---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQS1-1", "uniprot_id": "T184A_RAT", "id": "Q4QQS1-1", "name": "Transmembrane protein 184A", "aln": "MRNASGFLKTAGAPLVSATWL----PPSPPPAMPMVAAGPQMERVDNGSQGAP--QLFLTSALARGVSGVFVWTALLLTGHQIYSHLRSYTVPREQRFVIRLLFIVPIYAFDSWLSLLLLGGHPYYVYFDSVRDCYEAFVIYSFLTLCFQYLGGESAIMAEIRGKPIRSSC---FYGTCCLRGMSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASVSLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIPEVQAVDGTRVGAGTLAAGYQNFLICIEMLFASLALRYAFPSQVYSEKK------------NSPAPPAPMQSISSGLKETISPQD-----------------------------------------------------IVQDAIHNFSPAYQQYTQQSTHEA---------------PGPGQGGHPSPSTHPGPASGSGGGKKSRNIEKRMLIPSEDL---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZMB5-1", "uniprot_id": "T184A_HUMAN", "id": "Q6ZMB5-1", "name": "Transmembrane protein 184A", "aln": "MSNVSGILETAGVPLVSANWP----QPSPPPAVP---AGPQMDHMGNSSQGAP--WLFLTSALARGVSGIFVWTALVLTCHQIYLHLRSYTVPQEQRYIIRLLLIVPIYAFDSWLSLLLLGDHQYYVYFDSVRDCYEAFVIYSFLSLCFQYLGGEGAIMAEIRGKPIKSSC---LYGTCCLRGMTYSIGFLRFCKQATLQFCLVKPVMAVTTIILQAFGKYHDGDFNVRSGYLYVTLIYNASVSLALYALFLFYFTTRELLRPFQPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVETSGGNKLGAGTLAAGYQNFIICVEMLFASVALRYAFPCQVYAEKKE-----------NSPAPPAPMQSISSGIRETVSPQD-----------------------------------------------------IVQDAIHNFSPAYQHYTQQATHEA---------------PRPG--------THP--SGGSGGSRKSRSLEKRMLIPSEDL---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36142-1", "uniprot_id": "HFL1_YEAST", "id": "P36142-1", "name": "Vacuole membrane protein HFL1", "aln": "------------------------------------------------------MENKLLCWWLYWPCVYSSIIATIISFYTITRHLLNYRKPYEQRLSIRILLLVPIFSVSCASGIIKP--EAAQFYVDPIREFYEAFVIYTFFTFLTLLLGGERNIITVLSLNHAPTRHPIPLIGKICKPIDLSDPFDFLFVKKGILQYVWFKPFYCFGTLICSAWKLP--------KFEIFLNVFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYWQSIIIQGLVVTGKLG-------TGNQDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYTAFSIPYG--ARMKFIYALKDFLGCGDLIWDFKQTLFAGP------------------------------------------------------LYYNYRNFDPEAMDLLSTRQQSG-------------ATMERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEESWEDDIAGQRTFPEDPNYPVVHDYTMGHRYSRSMNDLRRDVQSRSSMAC-------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * *: : * *: :*:* :***::... .: .*... *: *** ***.*: * : : * . : * . **: .:*. . ::: . :: :. * * ::*.* **: * * * **: :* ::* *::*.::: * . : . :: ::*:**. :: :*. : : .: .. : : . . : ", "identical_positions": 44, "similar_positions": 79, "identity": "6.97%" }, { "cls_id": "homologset.agr.SGD:S000001760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920G8-1", "uniprot_id": "MFRN1_MOUSE", "id": "Q920G8-1", "name": "Mitoferrin-1", "aln": "MELRRGGVGNQAAGRRMDG---------------------------------DCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLAN-----------------------------------GVAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSG-RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLENRTLY--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H23-1", "uniprot_id": "MFRN1_RAT", "id": "Q66H23-1", "name": "Mitoferrin-1", "aln": "MELRRGGVGSQAAGRRMDG---------------------------------DCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLAN-----------------------------------GIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSG-RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRTLY--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYZ2-1", "uniprot_id": "MFRN1_HUMAN", "id": "Q9NYZ2-1", "name": "Mitoferrin-1", "aln": "MELRSGSVGSQAVARRMDG---------------------------------DSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLAN-----------------------------------GIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISG-RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q287T7-1", "uniprot_id": "MFRN1_DANRE", "id": "Q287T7-1", "name": "Mitoferrin-1", "aln": "MELRTDAV---LASLEMSE---------------------------------PVKN---------DEDYESLPAHASLGTHMTAGAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLRGLNITVLGAGPAHALYFACYERIKRSLSDVIQNGGNSHIAN-----------------------------------GVAGSVATVLHDAVMNPAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYEFMQEHFNPHRQYRPETHIISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSG-HLSGMVNALRTVYRLGGVPAFFKGIQARVIYQMPSTAIAWSVYEFFKYFLTQHESHVQEVSHKTSPT--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R0Z5-1", "uniprot_id": "MFRN2_MOUSE", "id": "Q8R0Z5-1", "name": "Mitoferrin-2", "aln": "MELEGRSAGGVAGGPAAGP------GRSPGESALLDGWLQRGVGRGAGGGEAGAYQPPVRLDPESGPEYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIAN-----------------------------------GAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALNSNITG--HITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR-----AGK---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V865-1", "uniprot_id": "G3V865_RAT", "id": "G3V865-1", "name": "", "aln": "MELEGRSAGGVAGGPAAGP------GRSPGESALLDGWLQRGVGRGAGGGEAGAYQTPVRLDPESGPEYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGIEPPRAGPHFPNSLGLAAVSASQPRMVWSGSLGLGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALSSNITG--HITGMANAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR-----AGK---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A46-1", "uniprot_id": "MFRN2_HUMAN", "id": "Q96A46-1", "name": "Mitoferrin-2", "aln": "MELEGRGAGGVAGGPAAGP------GRSPGESALLDGWLQRGVGRGAGGGEAGACRPPVRQDPDSGPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIAN-----------------------------------GAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITG--HITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR-----AGK---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T292-1", "uniprot_id": "MFRN2_DANRE", "id": "Q7T292-1", "name": "Mitoferrin-2", "aln": "MTADTSSGDAAVAGASAGAEIHWFGGRFWGVSESLVGTLTPRIS-GEPDLHVGHFYGSQEASDLSEPDYEGLPQGASTSTHMLAGAVAGIMEHCLMFPIDCVKTRMQSLQPEPAARYRNVMDALWRIMRTEGIWRPIRGLNITAVGAGPAHALYFACYERLKKVLSDIIHPGANSHLAN-----------------------------------GAAGCVATLLHDAAMNPTEVVKQRMQMYNSPYRSVLDCMRCVWQREGALAFYRSYTTQLTMNVPFQALHFMTYEYLQELLNPQRHYNPSSHMVSGALAGAIAAAATTPLDVCKTLLNTQESLAVDSVSRSGRHITGLGHAFRTVYRLGGLPAYFKGVQARVIYQMPSTAISWSVYEFFKYMITKHQHEKRRIQRDAEK---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAY3-1", "uniprot_id": "MFRN_DROME", "id": "Q9VAY3-1", "name": "Mitoferrin", "aln": "MNID---------------------------------------------------------------DYESLPT-TSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSP--PTKNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYVIS--------------------------------------GAVATLIHDAISSPTDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLT----------RGMIEASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYLCGLDADQYKSSITGSSEPRKADYVLPRTTDEEQIDQEREAAKEKDTTATLHSAPTSVNASGAIKTVCELSTRPAGPTINLHTRHTDVKSPYERGFST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23500-1", "uniprot_id": "MRS4_YEAST", "id": "P23500-1", "name": "Mitochondrial RNA-splicing protein MRS4", "aln": "MNTSELSIA-------------------------------------------------------EEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPIDALKTRVQAAGLN-KAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTYEFCKARLISPEDMQTHQPMKT-----------------------------------ALSGTIATIAADALMNPFDTVKQRLQLDTN--LRVWNVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGISGATCAALTTPLDCIKTVLQVRGSETVSIEIMKD--ANTFGRASRAILEVHGWKGFWRGLKPRIVANIPATAISWTAYECAKHFLMKN----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** ** :. :: ***.**::** :*:*:*.:***:*: : .: : : ** :* . ******::**. ** * . . : . * :**: ** .* :.:***:*: .. . : : ** *** :* * *.**:*: :.:* ** .: .* .. *.* * .*. :** .** ***** **:*:.: . : * * : .: * .:::* .*:: .:*:***.*:.** *. : ", "identical_positions": 87, "similar_positions": 83, "identity": "17.65%" }, { "cls_id": "homologset.agr.SGD:S000001761", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810K3-1", "uniprot_id": "SGPP2_MOUSE", "id": "Q810K3-1", "name": "Sphingosine-1-phosphate phosphatase 2", "aln": "--------MAELLRSLRDSQLVARFQRRCGLFPARE-------------------------------------------ASG---------------------------------EEHVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPNLSRRLVVIWVLVMYIGQVAKDILKWPRPSFPPV--VRLEKRIIAEYGMPSTHAMAATAISFTLLI--STMDRYQYP-FILGLMMAVVFSTLVCLSRLYTGMHTVLDILGGVLITAVLIALTYPAWTLIDSLDS-ASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTIVAAGAGVTLGFWINHFFQLVSKPT-----PSLPVIQNIPPLTTDMLVLGLTKFMVGIMLILLVRQLVQKLSLQVLFSWFKVVTRN-KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LUJ0-1", "uniprot_id": "A0ABK0LUJ0_RAT", "id": "A0ABK0LUJ0-1", "name": "", "aln": "--------MAELLRSLRDSELVARFQRRCGLFPGQE-------------------------------------------ASG---------------------------------EKHVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPYLSRRLVVIWVLVMYIGQVAKDILKWPRPSSPPV--VKLEKRVIAEYGMPSTHAMAATAISFTLLI--STMDRYQYP-FILGLIMAVVFSTLVSLSRLYTGMHTVLDVLGGVLITAVLIALTYPAWTLIDSLDS-ASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTVVAAGAGVTVGFWINHFFQLVSKPT-----PSLPVIQNIPPITTDMLVLGLTKFMVGIMLILLVRQLVQNLSLQVLFSWFKVVTKN-KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWX5-1", "uniprot_id": "SGPP2_HUMAN", "id": "Q8IWX5-1", "name": "Sphingosine-1-phosphate phosphatase 2", "aln": "--------MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADP------------------TERAARVPGVEHLPAANGKGGE-------------APANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPV--VKLEKRLIAEYGMPSTHAMAATAIAFTLLI--STMDRYQYP-FVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDS-ASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPA-----ESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN-KEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JI99-1", "uniprot_id": "SGPP1_MOUSE", "id": "Q9JI99-1", "name": "Sphingosine-1-phosphate phosphatase 1", "aln": "MS--LGQRLALLASRLQEPQRVASFQRLCGVEVPLSSPAADEDAET----EVRGAPGEPRRRGRQPGAEDSPAKADCCGAPNGVRNGLAAEPGPTGPRRAGSQ--RRNSLTGEEGELVKVSNLPLYYLFCLGTELGNELFYILFFPFWIWNLDPFVGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPV--IKLEVFYNSEYSMPSTHAMSGTAIPIAMFL--LTYGRWQYP-LIYGLILIPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQ-TYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYTLGLSLEPS-----LHMLPLA-IPPLTVTLFGKAILRIVLGMLLVLFVRDIMKKITIPLACKLSSIPCHDIRQARQHMEVELPYRYITYGMVGFSITFLVPYVFSFIGIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99P55-1", "uniprot_id": "SGPP1_RAT", "id": "Q99P55-1", "name": "Sphingosine-1-phosphate phosphatase 1", "aln": "MS--LGQRLALLAIRLQEPQRVASFQRLCGVEVPLGSPKAGEDAET----EVRGAPGDPRRRPRQSGADGSPAKPDCCGAPNGVRNGLAAEPGPTGPRRAGSL--RRNSLTGEEGELAKVSNLPLYYLFCFGTELGNELFYIIFFPFWIWNLDPFVGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPV--IKLEIFYNSEYSMPSTHAMSGTAIPIAMIL--LTYGRWQYP-LIYGLILIPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQ-TYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYNLGISLDPS-----LHTLPLA-IPPLTVTLFGKAILRVVIGMLLVLFVRDIMKKVTIPLACKLFGIPCHDLRQARQHMEVELPYRYITYGTVGFSITFLIPYIFSFIGIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PZN9-1", "uniprot_id": "A0A8M1PZN9_DANRE", "id": "A0A8M1PZN9-1", "name": "", "aln": "MAGGIKAGFVRLLHYLQDPQHVARFQRLCGVRGSDTRDSVRNGVQGTRSGDVHNGGGDATRR-RKAGAETDTEKRNNGLANGTAGENVNGDNNGHDALGSAVKPSRRNSLTGDAGQEFLIENKFLFYLFTLGTELGNELFYISFFPFFMWNVDAYVSRRLVVVWVWVMYLGQCTKDVFRWPRPASPPV--VKVEMFYNSEYSMPSTHAMSGTAIPLSLFL--LTYGRWEYP-MLLGLSLAISWCVLVCLSRIYMGMHSILDIIAGFLYSLLILVVFSPALDIIDTFNR-THPYAPLMIISLHVGLGLFSFTLDTWSTSRGDTAQILGSGAGIALASHVNYHLGLLPDPP-----ASAFPLQ-PPSFTLSLVALCLLRFFLGVLILLATRAVMKALTIPLVCWVFGIPSNDVRKARQHMEVELPYRYIVYGTVGLNALFLVPFLFAHVGLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23501-1", "uniprot_id": "DS1P2_YEAST", "id": "P23501-1", "name": "Dihydrosphingosine 1-phosphate phosphatase YSR3", "aln": "----MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHPAEHFES-----------------QMSWLRFQTRQYLTRFTDNQSD-------------------------FVHSLQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMPVWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSSHSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFSGAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDSVAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLRPLVGVASVIVWKDVISKTAVYTLLIKLLRFHDDRSEKVHFHNETSEEEECLLYSGVSKVEIVGRFLIYAGIPTTVFLLCPVFFTWTNLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : * . . * : :*..:**: .:*: * : * :: : :*:. ** *** *** : :. **. **:*: .**:.: :: . :* : * : : : :.*:* *** :**::.* : : : : :: *: : . : .. *:. .:. :*: . . : .: :. : ::: . . : : .: ::*: ::: * : : * .. .: ", "identical_positions": 40, "similar_positions": 96, "identity": "8.89%" }, { "cls_id": "homologset.agr.SGD:S000001762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38650-1", "uniprot_id": "DYHC1_RAT", "id": "P38650-1", "name": "Cytoplasmic dynein 1 heavy chain 1", "aln": "MSETGGG--EDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGDAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGD---EGEEEKEFISYNINIDIHYG-VKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPIITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEAPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFN-ALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESARVRGRSGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLN-LHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAP-QVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMIVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRSRDGPVALEESYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLSKWQALLVQIRRARGTFDNAETKKEFGP-VVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS------ELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDSSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGNVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSPGNVKRERIQKIKREKEERG-EAVDEGEIAENLPEQEILIQSFCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTDLREELKKVCKEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQK-RQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDLLSTDMIFNNFLARLRTIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSMLHQGCRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRALRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVN-FSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTEN-AIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSVITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTMGEPTYDAEFQHFLRGKEIVLSAGSTPKVQGLTVEQAEAVARLSC-LPAFKDLIAKVQADEQFGIWLESSSPEQTVPYLWTEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP----GWLMQLEKKLHSLQPHACFRLFLTMEIN-PRVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRMCKSPNERARLYFLLAWFHAVIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD----GHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDFTS--DGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAAAGGAKELKNIHVCLGALFVPEAYITATRQYVAQANSWSLEELCLEVNVTAS-QSTTLDACSFGVTGLKLQGATCSNNKLSLSNAISTVLPLTQLRWGKQTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHU4-1", "uniprot_id": "DYHC1_MOUSE", "id": "Q9JHU4-1", "name": "Cytoplasmic dynein 1 heavy chain 1", "aln": "MSEPGGG--EDGSAGLEVSAVQNVADVAVLQKHLRKLVPLLLEDGGDAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGD---EGEEEKEFISYNINIDIHYG-VKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPIITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEAPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFN-ALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESARVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLN-LHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAP-QVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGP-VVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS------ELTLGQIWDVDLQKNEAVVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERG-EAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQK-RQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNVPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVN-FSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTEN-AIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQGLTVEQAEAVVRLSC-LPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPTTPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP----GWLMQLEKKLHSLQPHACFRLFLTMEIN-PKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD----GHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKARTDSTS--DGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTAS-QSATLDACSFGVTGLKLQGATCSNNKLSLSNAISTVLPLTQLRWVKQTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14204-1", "uniprot_id": "DYHC1_HUMAN", "id": "Q14204-1", "name": "Cytoplasmic dynein 1 heavy chain 1", "aln": "MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGD---EGEEEKEFISYNINIDIHYG-VKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFN-ALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLN-LHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAP-QVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGP-VVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS------ELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERG-EAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQK-RQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVN-FSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTEN-AIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSC-LPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP----GWLMQLEKKLHSLQPHACFRLFLTMEIN-PKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD----GHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTS--DGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTS-QGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37276-1", "uniprot_id": "DYHC_DROME", "id": "P37276-1", "name": "Dynein heavy chain, cytoplasmic", "aln": "----MGDSLENPDTSVDPIVNLSIANYDAFANYLRKAVTILLPEDDVVPASLNDALDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDKMAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPTKPAVG--DDGNVVETK----QPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFN-ALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKIEDRASIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLS-LRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKE-VDTSMDTDAPAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVSQT---YRNLLTKLPEG-KILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGP-IIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLS------DLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGK-IDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKES----ITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINK-RQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIKPAKDK-EEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTEN-AIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTS-ESNLDAEFNFFLRSREGLLAN--PTPVEGLSAEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAP----QWLVQLEKKMHSLQPHSGFRLFLTMEIN-PKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELLLASTIMMDLPVTILKWIKIS-SEPRISKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVLTSTALN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36022-1", "uniprot_id": "DYHC_YEAST", "id": "P36022-1", "name": "Dynein heavy chain, cytoplasmic", "aln": "----MCKNEARLANELIEFVAATVTGIKNSPKENEQAFIDYLHCQYLERFQFFLGLLDGREFDTLFVFLFEELDRTIVTID--------------------IGEEAIYDANLANKKYSTLLIIKSRSVIVDAEPIATQISAIYLPGPVNAGNLASIITHGVSSVFGQLIKSDTKTYS--VETIDKTRRKLDDISKQFQQLHTSIETPDLLAMVPSIIKLAVSKGATSHDYANYLPS-NDLESMRFLNILQSIANKWFLVLKQTLAIDRDIKNGSFLDEVEFWSNFYEVLKSLIEQTQSQEFQVCLSVLTNAKRFHNLTNLLNEGSLSDKFKLADKYNQFLSSIPIDEVRQASNLEDLQELFPVLASSLKKFRYSGYPVQRFVVLMDKISQEVMDAILSNLS--DLFQLEYGSFLGLYEKSAGMIEEWDDIVQDVNLLIREDLR-KRAPQELLIQKLTFTSASVKATLDEILSTRKRFFSLAETIKSIS-------------------------------PSTYHEEIQRLYHPFEQIHDISVNFR--LKLEQAESEFSKNMLDLEKKLQNTLASFMDSDHCPTEKLSYLVKFKPLMELCPRIKVKVLENQQILLLEIKKDIRQLETGLELLP---KILHVEALNNIPPISARISYFLNVQSRIDNIVQYLEALFGSNWNDTLEGRSISTSIVQLRKETNPHDVFLHWLGNFPEK---ATANLLTTPILKLIRNNEDDYELKVNFDFALAAAYSELRSLTYMAFQVPSHIVRIARTYMYLYPRAINLVELIQTFFSLSKSLSYTFYTNIFLKRNVQTVWLLLQQILITPWES---------LQEESSEMSCSVHSLARLEKSIDGILSDYQILKNSEPQFAKEFSGLKSFDGTADDLHEVEEIISNIQAIFENLFTKGLTNVSDHISTFNNLIISIILEKVRLNLK-------------KMHFPKHVLKLSFNEGRITSSPSLAAMKRSLLKDIEALLNKVVLINFLHDPDHPLSTTLTFNSLVIKLKDDIQN----------CIEQVQNLHCKINSYVKEWQKMEFLWQITEEAFLEVVDNSTQRCFGILKGLLDSQSKFDLIISRNNFSKNLVLHTEDAQRHIRSKMDSWILYVSKHLLTIYERDARKLHEDMNRDREAVEDMDINFTSLKNITVIIEAVNVNKRHLTERDIQIKLLGSVMRALTKLKVRFPSHFVYIDQLDNDFSSLRQSLSYVEQELQKHRVVIAKSLEEGVENINNLSQSLNESWSVRKPISPTLTPPEALKILEFFNESITKLKKKMHSVAAAAKMLLIPVVLN-----DQLTHVVEEVKTYDLVWRSIKNLWEDVQRTFETPWCRVDVLLLQSDLANFLRRADELPRAVKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRHWNMIFRDIGKRQIQKNLLDKLEFSLKDVMVLNLTLNEILLTKIIERAQKEFVIEKSLNRIKKFWKEAQYEVIEHSSGLKLVREWDVLEQACKEDLEELVSMKASNYYKIFEQDCLDLESKLTKLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSLTSEYKMITTRAFQLDTTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYFLGNDDLLKIIGSGKHHDQVSKFMKKMFGSIESIIFLED--FITGVRSVEGEVLNLNEKIELKDSIQAQEWLNILDTEIKLSVFTQFRDCLGQLKDG--------TDIEVVVSKYIFQAILLSAQVMWTELVEKCLQTNQFSKYWKEVDMKIKGLLDKLNKSSDNVK--------KKIEALLVEYLHFNNVIGQLKNCSTKEEARLLWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLIGFATLTDSLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVGITQIGAWGCFDEFNRLDEKVLSAVSANIQQIQNGLQVGKS----------HITLLEEETPLSPHTAVFITLNPGYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLSSKCSSMNHYHFGLRTLKGVLRNCS------------------------PLISEFGEGEKTVVESLKRVILPSLGDTDELVFKDELSKIFDSAG-TPLNSKAIVQCLKDAGQRS------GFSMSEEFLKKCMQFYYMQKTQQALILVGKAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTSILRRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNFRILFETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLN--------------------KSYEALDNKLSMFELDKLKDLISDSFDMAS--LTNIFTCSNDLVHILGVRTFNKLETAVQLAVHLISSYRQWFQNLDDK-SLKDVITLLIKRSLLYALAGDSTGESQRAFIQTINTYFG-HDSQELSDYSTIVIANDKLSFS----SFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNSKRGIILCGPPGSGKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIKNLVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPPTDPGRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFKLVPEFRSYTEPFARASVHLYNECKARYSTGLQSHYLFSPRELTRLVRGVYTAINTGPRQTLRSLIRLWAYEAWRIFADRLVGVKEKNSFEQLLYETVDKYLPNQDLGNISSTSLLFSGLLSLDFKEVNKTDLVNFIEERFKTFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILTRFVAWLNGLKIVQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFLERMNTLLANADIPDLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLHVVFTICDPTNNKSSAMISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFTDFIVPEVNKELVFTEP-IQTIRDAVVNILIHFDRNFYQKMKVGVN------PRSPGYFIDGLRALVKLVTAKYQDLQENQRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKMLMEQNESERKQEATEEIKKILKVQEEDIRKRKEVVMKSIQDIEPTILEAQRGVKNIKKQQLTEIRSMVNPPSGVKIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDTTLHMKPQIRKYMEEEFLSDPNFTYETINRASKACGPLYQWVNAQINFSKVLENVDPLRQEMKRIEFESLKTKANLLAAEEMTQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQANLDRSISLVKSLTFEKERWLNTTKQFSKTSQELIGNCIISSIYETYFGHLNERERADMLVILKRLLGKFAVKYDVNYRFIDYLVTLDEKMKWLECGLDKNDYFLENMSIVMNSQDAVPFLLDPSSHMITVISNYYGN-KTVLLSFLEEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLISREFNHAGNRVTVEIGDHEVDVSGDFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKESIETRIFDITLTEENAEMQRKREDLIKLNTEYKLKLKNLEKRLLEELNNSQGNMLENDELMVTLNNLKKEAMNIEKKLSESEEFFPQFDNLVEEYSIIGKHSVKIFSMLEKFGQFHWFYGISIGQFLSCFKRVFIKKS--RETRAARTRVDEILWLLYQEVYCQFSTALDKKFKMIMAMTMFCLYKFDIESEQYKEAVLTMIG------------------------------------------VLSESSDGVPKLTVDTNNDLRYLWDYVTTKS-------YISALNWFKNEFFVDEWNIADVVANSE----------------------NNYFTMASERDVDGTFKLIELAKASKESLKIIPLGSIENLNYAQEEISKSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFKMFMTCHLTGDKLPAPLLQRTDRFVYEDIPGILDTVKDLWGSQFFTGKISG-VWSVYCTFLLSWFHALITARTRLVPHGFSKKYYFNDCDFQFASVYLENVLATNSTN-------NIPWAQVRDHIATIVYGGKIDEEKDLEVVAKLCAHVFCG--------------------------------------------------------SDNLQIVPGVRIPQPLLQQSEEEERARLTAILSNTIEPADSLS-----------------SWLQLPRESILNYERLQAKEVASSTEQLLQEM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .::. : .: . * : .* : : : ** : ::: . : : * : : :* ** *: :.: :*: : :. .* ::*::.::. * . ::.. :: : ...:*: ::. : :*: .*: *:: :. . : .: :.:*. *** **. .*:*: :::. ::** .*: *:*:.** *: ..* : *: :* *. : *.:*.:.**** ..: .: .*.: : . .** ::..:*:::: .*::*:.:: . : : *:*.* : **:** : *:: **::: . :*. *. *::: : .* : . ::. *** :.:: *:*: :: ** : :: ::. : .::: ::.: . *::. .* .* : :. **:: *. .:::. :.:. . * * ..:.:.: :*.:: * . :.: : ..* : : :*: : : *:*: : * * *: .:*.**. *. ::: : ::. :.::**::. * : ::: :: :: :* ::*..*: :**:.:. . .:* : . ::* .* :. :: :..::* : : .*:*** : : .*:*.:. :.*:** **. *: :** **.*:* ::*: :.:. :: : * *: : : *** * * ::. .*..* :*:.:* : . : . * : :. :: . . *:. .:: : : :: .:. : ::.: : . : . .:. . :: : * :: :.: : *.: : .: ::: * * ::. : :. ... :: : . . : ::..**. * : : **:: : : :.:. . * : :: .** ::. :. :::. ..* :: * *** . :: : : .:*..:.:.* :* .:: :* .: . :* *: *:.: : *::: . * * : :.:** ::::*:::.::.::.: : : :* : . : .: . ::. : .: .*. ** .: * :**: * ::: . :**.. .. . * : * : ::: .:**:: ** .:.::* :::. * ** *: *:.:* :: : ..:* :: : *: : :: .:* :::***. *** ***: : : : . : . :::* :: ::* ** ::..:: ** *:.:*: *::::: *: : :::::.. :::* ** * : **.::.: :** * ***:**::.* *.**.:: : *::** *: * **: . **: :**:**.:*:*:::*: : .:. : .::*::* .: :*: * * *:.:*. :***:* .******:*::***:***..*: ::.*.:****..: :*:: *: .: *: * *** : : :. : : :***.:::.:::.:: . : :.: ::: .** * ::*:**: *:* **..*. . :. : .: .** :*.* :*:* *: * :* . * * : . : * :** . : *:.: * :. : * ***:*: ::*: *** : *:*::*. : **. **********:***:*::***.*:*****::**:*.:.*::**: *:************:*::*** * ::* **:.*: . *: ::. :**. *:***:**** ***:**:**** **.::*..*: **:::* **. :: ** *** *::* ..: *. .**.****:**.** . . ::* :: :::*. ..::*.* * :: . **.:* .. : . : : ::.. :. * . . :::* :*:* : : ::.*::** :*.**: :*:.::.*: ::* .*.::**.*.::*: *** : * ** ***** :**:: *.: * ::: * *::**.*:***:** :********:*********.:***.*::**.::*..:* **::***::*** *: * . ::: * . : : . ::::: : .: :. :.. : : . **:.. :. * : ..: : . : : * : : * : *:*:: . :*::: . :. :. : *. . * : ::.:* .: ::* :.:*:*:* **:*:**:**::** ::* * .:: ::*********** : .*** . :***:***. **.* :*.::.:: :* *.:*:.* * . * ***********.:*.**:*.*: *:**::*: **:::.:: **.:***::************ *:*.** **..::*:.**. **.*** : :*:::*:* :* *:**:: * *.:* .: *:: . *.**::****:** ***: *:.. .:..*:*:**:** *:* **** .*:. :: : . *::*. : : . .:*:*. ** *: *:: :* :::. *:*.* :***:**:*:.:.::**:***** ::* ***::***.* :*** *:*****:***.: * *:*.: . .*** *: .: .. *:.: .:*:****:*::.***********.::*.**:*:** .*:.: :: :: **:**: :***.**. :: :*******: .::. .. :********::**:***. .:: **.:::. : :* .:: .*: : * : *:*::* :...:.::* .: . :* :::* :. .:* * .:*:*:* .:****.*: *:* :*:*:.: * *. ** *: *. .*.:*. :*:*:*:*: ::**: * * * .:: * .: .:**::::** .**.*:**:*.*:*:*.***: **:.:*::* :** . ::*:.*: .* :::** .** : .:. :*: *:.:::*:*.:.:* :**** ****: :*. **::::.:*:.*:***:*:: :* :: . . .::: .:** ** *.:*: ** :.:***::: *:*:::** :*:***. *:*** .*:: *.. . : *: ::*: : :* *::::: * :::. .: * ::: .: :** . **:::* .* :* ** :*::: : *:::***.: .: * * . * . ***::.* *.**.*:***. :::** * :**::. ::.**..::*.** : :**:::*:* .* :*: : **: ::* : *** :*:*...:.*:::: :: .*. *..:::.**.**:**: *::*:*::*** **: **: :*.:*::* ::.**:.**:** :: :*:.*:: .: :.:.: ::* :. . .*: ::.: *.*::* *: **. : *: ::. . *:. : *:* : :.: .: : :: :*: : : . * :* : : * : . * ..:: : ** .. : : :: *: : .: : . .* *. :.* . *.: :: :** .: .:. *.:** *.:* *:. *. : * *::*:*:::: :* : :: :: : * *::*:* .:. ::*. **: **:* **: .: :.: : . . ***:****:: * * .* *::*** *.:.*:: *. ::. : .: . ::** : :: :***::*:: * .:: .: ::* . * . *. : . :*: . *: *: : : **.* :.: :* : . . : :*: ", "identical_positions": 1055, "similar_positions": 1646, "identity": "22.54%" }, { "cls_id": "homologset.agr.SGD:S000001763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92730-1", "uniprot_id": "RND1_HUMAN", "id": "Q92730-1", "name": "Rho-related GTP-binding protein Rho6", "aln": "---------------------------------------------------------MKERR--APQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET-EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKP-SPLPQKSPVRSLSKRLLHLPSRSELISST---------FKKEKAKSCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BLR7-1", "uniprot_id": "RND1_MOUSE", "id": "Q8BLR7-1", "name": "Rho-related GTP-binding protein Rho6", "aln": "---------------------------------------------------------MKERR--APQPVVVRCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET-EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKS-SPVPPKSPVRSLSKRLLHLPSRSELISTT---------FKKEKAKSCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L6G2-1", "uniprot_id": "A0ABK0L6G2_RAT", "id": "A0ABK0L6G2-1", "name": "", "aln": "---------------------------------------------------------MRGRSGTARGSCGGEESRPLWREYSSSPASLLRPLLSACRNSEAAAGRLRRRIIDVLE-DGGDSNCRACPRWGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKP-SPVPPKSPVRSLSKRLLHLPSRSELITST---------FKKEKAKSCSIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NAL2-1", "uniprot_id": "A0A8M1NAL2_DANRE", "id": "A0A8M1NAL2-1", "name": "", "aln": "----------------------------------------------------------------MD-GQHSRCKVVVVGDTQCGKTALLHVFAKDNYPENYVPTVFENYTASFEI-DKHRIELNMWDTSGSSYYDNVRPLAYPDCDAVLICFDISRPETLDSITKKWQVEAQEYCPNAKLVLVGCKLDMRTDVSTLRELSKQRLIPVTHEQGSLRARELGAVAYVECSSRMCVNSVRDVFHITTLVSVRREPAPSLKRSTSRRTLKRISNQPLLPVTSQATPLEAT--PTLREDRAKSCTIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QYM5-1", "uniprot_id": "RND2_MOUSE", "id": "Q9QYM5-1", "name": "Rho-related GTP-binding protein RhoN", "aln": "----------------------------------------------------------------ME-GQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEI-DKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRG-HRQLRRTDSRRGLQRSTQLSGRPDRGNEG--------EMHKDRAKSCNLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61587-1", "uniprot_id": "RND3_HUMAN", "id": "P61587-1", "name": "Rho-related GTP-binding protein RhoE", "aln": "-------------------------------------------------MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEI-DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKT-NKNVKRNKSQRATKRISHMPSRPELSAVAT-------DLRKDKAKSCTVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00246-1", "uniprot_id": "RHO4_YEAST", "id": "Q00246-1", "name": "GTP-binding protein RHO4", "aln": "MNTLLFKRKGGNCGNESNIVSQGSPSSSNLPESPGTLDEKNLPRLPTPFARSLSTIPSYEQMKRTNKLPDYHLKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLY-EADNLSDLVE----PSSAES---LAKRLGAFAHIQCSARLKEN-IDEVFETAIHTLLSDS--LYAPREPTHTIKNPFKRNTTRSDIDSSTGDTSVSISGTKRLRKNKCIIM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . :.:* . . :.. . : : *. *..:***.*.:.*.:::*:.:. ::.. . * * .:**.: ::*:* * *: : .* :* . * : :. *:.:** ::: *: : .:*. : : : : : . . . :. : :.* :*", "identical_positions": 27, "similar_positions": 77, "identity": "8.94%" }, { "cls_id": "homologset.agr.SGD:S000001764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZ69-1", "uniprot_id": "TRM2A_HUMAN", "id": "Q8IZ69-1", "name": "tRNA (uracil-5-)-methyltransferase homolog A", "aln": "-----MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEP----PVTRVADVVTPLWTVPYAEQLERK-----------------------QLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGG--TCAVAAPFDTVHIPEATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRH-QAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAG---------------DRCIHEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQDWAQLDAGS------MVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLVSRLASQH-------LVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNPR-AAMGNFVDLCRAP--SNRVKGIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BNV1-1", "uniprot_id": "TRM2A_MOUSE", "id": "Q8BNV1-1", "name": "tRNA (uracil-5-)-methyltransferase homolog A", "aln": "-----MSEPAA-EVPEPMEDCGQDAS---------AVPSSAAPLCQKEEAGPGPAAGPGTQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQSHKIKLFGQPPCAFVTFRSAAERDKALRVLHGALWKGCPLSVRLARPKADPMARKRRQEGDSEP----SVTQIADVVTPLWTVPYTEQLEQK-----------------------RLECERVLQKLAKEIGNTNRALLPWLLLQRQQHNKACCPLEGVKPSPQQTEYRNKCEFLVGVGVDGKDNTVGCRLGKYKGG--TCAVAAPFDTVHIPEATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSSRG-QAMAIAYFHPQKLSSEEVAGLKASLVCHFMEGPGKASGVTSLYFVEEGQRKTPSQEGLPLEHMAG---------------DQCIQEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQEWAQLDGGS------TVLDVCCGTGTIGLALAPKVKRVVGIELCQEAVEDARMNALTNELSNVEFHCGRAEDLVPGLVSRLSSHQ-------LVAVLDPPRAGLHSKVILAIRKAENIKRLLYVSCNPR-AAMGNFVDLCRAP--SNRVKGTPFHPVKAVAVDLFPQTPHCEMLILFERMQQHP-NGIEALEHQEFQTPRNLPDITPQETEISLS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VVV7-1", "uniprot_id": "Q9VVV7_DROME", "id": "Q9VVV7-1", "name": "tRNA (uracil(54)-C(5))-methyltransferase", "aln": "------MECFNAEIPADGVVNSIETE-----------EISENVVKADETTLANGEDEAGKAGEEYAYLERNEFTSEIFKVEVKNMGYFGIGEFKKLLRNTLKFDVTKIKAPTRKEFAFVCFRSQEDQQRALEILNGYKWKGKVLKAHVAKASADPLQKKRAAEEQESERKPKKQRTAVEATCPLSHIAYDQQIKQK-----------------------SEEMSALLAKYTQELRKVN---------PRAKPHLDKFQFHEVLPSPTVNGYRNKNEFTVGKNSVG-EVVVGFRLGCYSDG--SVEVAEVADLPHLPEQAKWAARSFQDLVRKSKFLPFNPDGNIGHFRQLMVRCSSATGELMLVAGIYSSNLSEDEQVELKQELKSFYEDLANDAPYKCSSLYYQDVKHREAGQTINPVEHISG---------------STHITDTIQGLQFRISPLAFFQINTEGANVLYQKAIDLVAPTKDT------TMLDICCGTGTITLAFAKHCKKVMGVEIVPDAIKDAEFNAEANGIKNAKFFTGNADDFIKSMVREALYDQEPGKPLDLIAVVDPPRAGLHHRSIAAIRSADAINRLVYVSCNPH-SAKRNFIELARPE--SKQYKGEPFYPKSAVAVDMFPHTMHTELVILFEREPKTKADEKSSPAEGAAQSKSEATEEAVSEENTTSVT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BQJ6-1", "uniprot_id": "TRM2B_MOUSE", "id": "Q8BQJ6-1", "name": "tRNA (uracil-5-)-methyltransferase homolog B", "aln": "------------------------------------------------------------------------------------MHNPRLFLSRAGFFSKPGLLPWDTGRPPDLSQSLLGRAYKGSFTSVIAKKHPSRQKYQKKQRHCR--DDSWQER------------------LADVVTPLWRLSYEAQLKVK-----------------------FEAQKKLLQSLESHLKVLHGVSDT---VAAHQSEGLRCLLHPIIPSPTTTGYRNKSTFSVYRSPDGNPKTVGYYLGTWKDG--NVVCLPCNHLKNIPEKHSQVAQYYEVFLRQSSVEPCLLFHEGGHWRELVVRTNRQG-HTMAIVTFHPQGLSEEEVCVQKVTLKDFFTKGPGAICELTSLYFQESTMTRCSHQQ-SPYQLLFG---------------EPHIFEDLLGLKIRISPDAFFQINTAGAEMLYRIIGELSGVNSES------LLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPQLLKSQKDEKL------TVAVVNPARAGLHYRVVRAIRNCRTIHTLVFVSCKPHGESTRNFIELCCPPNSAKQLLGDPFVLREAVPVDLFPHTPHCELVLLFTR-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GJ1-1", "uniprot_id": "TRM2B_HUMAN", "id": "Q96GJ1-1", "name": "tRNA (uracil-5-)-methyltransferase homolog B", "aln": "---------------------------------------------------------------------------MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQKKPSHLGPLDGSWQER------------------LADVVTPLWRLSYEEQLKVK-----------------------FAAQKKILQRLESYIQMLNGVSVT---TAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDG--NVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQG-HTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQ-SPYQLLFG---------------EPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDT------ILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQS------IVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QP75-1", "uniprot_id": "TRM2B_DANRE", "id": "A4QP75-1", "name": "tRNA (uracil-5-)-methyltransferase homolog B", "aln": "--------------------------------------------------------------------------------------MSSAFKAMRLHLTCP--LPKQVINIP---QTLFSYLITN--QRAINNSCKPVKTSNAKKPKLPTTKLSWEER------------------LSDTVTPLWRMTYEDQLQWK-----------------------YEHQKKIL------LKMMKELSQD---PTRAFSDHLNFPLLPIVASPVRDGYRNKSTFSVNKGIDGNPKTLGFYIGTGKAG--NIVCVHADHLLSIPSKHKMVARCYEDFIRLSPLRPCILFDDGGHWREITIRTNSTG-HTMAIVYFHPQSLTPEETDIHKAALVEYFTQGPGAICQLDSLYFQETTMTRCSHEQ-SQYQLLYG---------------QTHIYEEVLGFKFRISPDSFFQVNREAAEALYKTVAELSQPCVGG------TLLDVCCGTGAIGISLSPQMERVIGIELIEQAVEDAKFNAALNRVCNCEFLAGKAEVVLPDLMGSLSSDGG------LTAVVNPSRAGLHYRVVRALRNHSAIRRLVYISCKPDGEAMRNFRELCCSVGLVRRITGEAFKPVVAVPVDLFPHTPHCELVLVFER-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33753-1", "uniprot_id": "TRM2_YEAST", "id": "P33753-1", "name": "tRNA (uracil(54)-C(5))-methyltransferase", "aln": "MYEQFEFSFFFFENSDNKVKYKAHLISSIKRWSIITCMRCFWTVQKSIFKARFFACRNFVKKHNYKLISTMTGSTEMVPPTMKHTVDNKRLSSPLTDSGNRRTKKPKLRKYKAKKVETTSPMGVLEFEVNDLLKSQNLSREQVLNDVTSILNDKSSTDGPIVLQYHREVKNVKVLEITSNGNGLALIDNPVETEKKQVVIIPFGLPGDVVNIKVFKTHPYYVESDLLDVVEKSPMRRDDLIRDKYFGKSSGSQLEFLTYDDQLELKRKTIMNAYKFFAPRLVAEKLLPPFDTTVASPLQFGYRTKITPHFDMPKRKQKELSVRPPLGFGQKGRPQWRKDTLDIGGHGSILDIDECVLATEVLNKGLTNERRKFEQEFKNYKKGATILLRENTTILDPSKPTLEQLTEEASRDENGDISYVEVEDKKNNVRLAKTCVTNPRQIVTEYVDGYTFNFSAGEFFQNNNSILPIVTKYVRDNLQAPAKGDDNKTKFLVDAYCGSGLFSICSSKGVDKVIGVEISADSVSFAEKNAKANGVENCRFIVGKAEKLFESIDTPSENTS---------VILDPPRKGCDELFLKQLAAYN-PAKIIYISCNVHSQARDVEYFLKETE------NGSAHQIESIRGFDFFPQTHHVESVCIMKRI------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * : : : * . :* . . . * .. :. . . . : *: : : . : :* * . : : . : : : . :.:*. *** * : : ::* **:* : :. : .:* *:*: :::. *. .* * : * .* *.*: .. : .:::*.* * . : : ::::**: : * . * .. .*:**:* * * : :: * ", "identical_positions": 40, "similar_positions": 86, "identity": "5.79%" }, { "cls_id": "homologset.agr.SGD:S000001765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05765-1", "uniprot_id": "RS21_RAT", "id": "P05765-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRSTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQR2-1", "uniprot_id": "RS21_MOUSE", "id": "Q9CQR2-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRTTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63220-1", "uniprot_id": "RS21_HUMAN", "id": "P63220-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUG5-1", "uniprot_id": "RS21_DANRE", "id": "Q7ZUG5-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQINIAEVDRVTGRFNGQFKTYAICGAIRRMGEADDSLLRLAKTDSIVAK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76927-1", "uniprot_id": "RS21_DROME", "id": "O76927-1", "name": "Small ribosomal subunit protein eS21", "aln": "MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0V8-1", "uniprot_id": "RS21A_YEAST", "id": "P0C0V8-1", "name": "Small ribosomal subunit protein eS21A", "aln": "MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYVTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** *: *:*********:**** *.****:*:.:..** . **.:.* :* **:**.: ***: *.:: : ", "identical_positions": 38, "similar_positions": 24, "identity": "43.68%" }, { "cls_id": "homologset.agr.SGD:S000001766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R062-1", "uniprot_id": "GLYG_MOUSE", "id": "Q9R062-1", "name": "Glycogenin-1", "aln": "-MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRR-----------MVVLTSPQVSDSMRKVLETVFDDVIMVDVLDSGD------SAHLTLMKRPELGITLTKLHCWSLTQYSKCVFMDADTLVLS-------NIDDLFEREELSAAPDPGWPDCFNSGVFVYQPSIETYNQLLHLASEQGSFDGGDQGLLNTYFSG-WATTDITKH--------LPFVYNLSSISI-YSYLPAFKAFGKNAKVVHFLGRTKPWNYT---------YNPQTKSVNCDSQDPTVSHPEFLNLWWDTFTTNVLPLL--------------------------------------------------------------------------------------------------QHHGLVKDAS-----------------------------------------------------------SYL------------------------------------------------MMEHVS-------------------GALSDLSFGEAPAAPQPSMSSEERKERWEQGQADYMG-ADSFDNIKRKLDTYLQ-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08730-1", "uniprot_id": "GLYG_RAT", "id": "O08730-1", "name": "Glycogenin-1", "aln": "-MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRR-----------TVVLASPQVSDSMRKVLETVFDEVIMVDVLDSGD------SAHLTLMKRPELGITLTKLHCWSLTQYSKCVFMDADTLVLS-------NIDDLFEREELSAAPDPGWPDCFNSGVFVYQPSIETYNQLLHLASEQGSFDGGDQGLLNTYFSG-WATTDITKH--------LPFVYNLSSLSI-YSYLPAFKAFGKNAKVVHFLGRTKPWNYT---------YNPQTKSVKCESQDPIVSHPEFLNLWWDTFTTNVLPLL--------------------------------------------------------------------------------------------------QHHGLVKDAG-----------------------------------------------------------SYL------------------------------------------------MMEHVT-------------------GALSDLSFGEAPPASQPSLSSEERKERWEQGQADYMG-ADSFDNIKRKLDTYLQ-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46976-1", "uniprot_id": "GLYG_HUMAN", "id": "P46976-1", "name": "Glycogenin-1", "aln": "-MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRR-----------LVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGD------SAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLA-------NIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSS-WATTDIRKH--------LPFIYNLSSISI-YSYLPAFKVFGASAKVVHFLGRVKPWNYT---------YDPKTKSVKSEAHDPNMTHPEFLILWWNIFTTNVLPLL--------------------------------------------------------------------------------------------------QQFGLVKDTC-----------------------------------------------------------SYVNVLSD-------------------------------LVYTLAFSCGFCRKEDVS-------------------GAISHLSLGEIPAMAQPFVSSEERKERWEQGQADYMG-ADSFDNIKRKLDTYLQ-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LFW5-1", "uniprot_id": "A0A0B4LFW5_DROME", "id": "A0A0B4LFW5-1", "name": "glycogenin glucosyltransferase", "aln": "-MSKFAWVTLTTNDTYSLGALVLAHSLKRAKTAHQ-----------LAVLVTPNVSQAMRDRLKEVYNVVQEVNVLDSQD------AANLALLSRPELGVTFTKLHCWRLVQFEKCVFLDADTLVLQ-------NCDELFEREELSAAPDVSWPDCFNSGVFVFKPSVDTFAQITEFAVKNGSFDGGDQGLLNQFFAD-WSTADIKKH--------LPFVYNVTAYAS-YCYLPAFKQFRDKIKILHFAGKLKPWLIQ---------FNSETKVASVSS--EYAHAQDLIQLWWNIFCENVIQSLSTEMQTPGNVASDRPAGEMAQGSTTLECLCLNIIRTQSEFAADELHQRQQHEFYQQQKLHHHLLHVRQFRDPWADYYENLEKEPQEQEQEQQRHQHQQQHHNPSQNHSQDNGNADAAAHENDSTIANANATDWHHDDACHPPAPTRPLPQIQNQAHNANATANAEDFSFVDVNSNELNISQPPEHASYSSDTATPTATATPTATPTLTPTPHHSVHSQTVEKATSHQQEHEVAATTPPEAGLAGALSQLRIGQQRTPEQEAYENQMRRQCWESGQIDYTG-ADSFENIWKKISQTLERKTDKESEETDNDNDSDPANPLSSARLLNEAASILLHPPEKSPTSKAMKANGATGNGSHLDQSHPTNSPATNKQPANASASPNASLKQNPQKRQEKPQPQAEPELEPRPQPQPQPTEQHIRMQPGGGNGSVSKSGKQRSARKFK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36143-1", "uniprot_id": "GLG1_YEAST", "id": "P36143-1", "name": "Glycogenin-1", "aln": "MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCLIVTTSLFNGTLSELAKNILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFALIKARLWELTQFEQVLYLDSDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSGVMMLIPDADTASVLQNYIFENTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLSFTYNVTIPNLGYQSSPAMNYFKPSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVYEEFKEEHQLNNEVSKPKISDSDKTETPETITPVDAPPSNEPTTN--------------------------------------------------------------------QEIDTISTVEENVDNQNAEPVPNSDHSPAPN------------------------------------------PVPLDFTKWLTTFINKDHLTN-------------------------QPVNESREYSKENDNNIINSSSNRDQESPPNSTQELNSSYSVVSTQADSDEHQNAEEEDSTTDNASNSGEESHLDDISTAASSNNNVSNQPDGKNFSNSKENNISVESSPSNPEQKRSTDNIQKPSVSTNDLPDDVEPHTSVDDNIQYLEKDKEGYEEFLPDVYESNAIDNEEEFFDDDARDATEGETKTSAVADKQEDMKLTAEETNQPQQEMPNFKFDWEDSDYLSKVERCFPDDIFEYAVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * .** . * *.:.*. .::: . * . :*: :. *: :: : *: *:. : : :*:*:.****..:: * : * *.*:.: :::*:*** * : . .::.* .* .*** *****:: *. :* : . :: *:**.***:** :* .* :: *. *.* **:: * **:: * . *::** *: *** :. : : . . :. . . *: : ::: : : . :. .: : .: : *..: * . * * :* : : ", "identical_positions": 70, "similar_positions": 110, "identity": "9.32%" }, { "cls_id": "homologset.agr.SGD:S000001767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10630-1", "uniprot_id": "IF4A2_MOUSE", "id": "P10630-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14240-1", "uniprot_id": "IF4A2_HUMAN", "id": "Q14240-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKI1-1", "uniprot_id": "IF4A2_RAT", "id": "Q5RKI1-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60843-1", "uniprot_id": "IF4A1_MOUSE", "id": "P60843-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "--MSAS-----QDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60842-1", "uniprot_id": "IF4A1_HUMAN", "id": "P60842-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "--MSAS-----QDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GF11-1", "uniprot_id": "A0A8I6GF11_RAT", "id": "A0A8I6GF11-1", "name": "RNA helicase", "aln": "LSTTASPPNSFSDSRPRDNGPDGMEPEGVIESNWNETVDSFEDKNLSESLLRGMYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGSGKTATFAISILQQIELDLKATQALVLAPTSELAQQIQKVVMALGDYMGASCHACIEGTNVRAEVQKLQMEAPHIIMGTPGRVFDMLNWRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVILINTRRKVDWLAEKMHARDFTVSAM--------------EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYVHRIGRGGQFGRKGVASNMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7F7A6-1", "uniprot_id": "F7F7A6_RAT", "id": "F7F7A6-1", "name": "RNA helicase", "aln": "--MWAWQQRPHLGAVSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02748-1", "uniprot_id": "IF4A_DROME", "id": "Q02748-1", "name": "Eukaryotic initiation factor 4A", "aln": "--MDDRN-------EIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10081-1", "uniprot_id": "IF4A_YEAST", "id": "P10081-1", "name": "ATP-dependent RNA helicase eIF4A", "aln": "----------------MSEGITDIE-ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ--IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:: :. *::.:.: .*:* :* *.****::.****:*********:* :.* **:******:***.**:*: **::: ..: ***:**** *** ***:*::**. :* **** **.. : . *. :::******:* :: : : .. **:*:********* ***:** ::* * . **:******* *****: ***:*: *****:*******:***:**:.*::* * ***:::::**:**: ******: *: :: .*****: :*******:**:**********************:*:***:*******:******* *::*::* ::::* ** * :**:* ::* *: ", "identical_positions": 209, "similar_positions": 104, "identity": "50.48%" }, { "cls_id": "homologset.agr.SGD:S000001768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVY0-1", "uniprot_id": "RL1D1_MOUSE", "id": "Q8BVY0-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "MKGSASESPSASVAEATTTDVQVTPTALLQLDREQIRKAVEVISNRSKSKKNNNELLLSGSENLFLMVILWKIPEKELRVKVPLPHSILSESSDVCLFTKDEFDS-PEQTEGFYKKLLKKHGVNTISQIIPFKTLKTEYKAYEAKLRLLGSFEVFITDARIRRHLPSHIGRHFYQRKKVPVSVNLLAKNLSKEINRCITGTVLNISKRGSCSTIRIGHTGMETEHIVDNILAVSEMLSEKLPEKWQSVKLLFLKTEKSVSLPIFSSFVTSQDEN-AVSLRSLRKQELKKRKRE-NAKLKKESKMLRKKSKKATSLLTQSGLAS---SAPAKSPGAQKKKTNKAHKKQ--------KVTEECEEAIPQLVPIG-ETPDKENVKMQENITGKTPKSKS-DPSTPKGKKRKALLATETPEASAPGTSGKK--------------------QKKDVQEFRKPEASSFSTPRKSGKKASNTPR--DKKTKAAHSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76021-1", "uniprot_id": "RL1D1_HUMAN", "id": "O76021-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNENESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNKHGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVPVSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36144-1", "uniprot_id": "RL1D1_YEAST", "id": "P36144-1", "name": "Ribosome biogenesis protein UTP30", "aln": "MVESNDIIKSGLAEKALKALILQCEENPSLKNDKDIHIIINTGKKMGINRDN----------------IPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTK-------------DEHTSELFKEIISVKNLRRRFKG-SKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKK-----------------------------------------------LPYMIRMSKEVKLKRQQMVEKCDPIYVR-AQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQN----IQDTINFLTDKSKRPQGGVIKGGIIS----IFVKTSNSTSLPIYQFSEAR----------ENQKNEDLSDIKL------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . *. . . .: : :::: ::. . .:.* : ** .: :: . .* :.* . : :: . .:* : ..:**..:.*: .:*. . :* .*:..::* *::: **. :* :**: .* : :: ::: :. * : :. . :::: : :: :*::.. *: : :*:. . :: :. : .::::. . : :..: . .*.. : . : : : :: :: :.:: ", "identical_positions": 28, "similar_positions": 126, "identity": "5.71%" }, { "cls_id": "homologset.agr.SGD:S000001770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCP9-1", "uniprot_id": "D3ZCP9_RAT", "id": "D3ZCP9-1", "name": "Transcription initiation factor IIE subunit beta", "aln": "MMNSNVEVIMDPSLLRDRELFKKRALSTPVVEKRAVPSESPSSSS----KKKKAKVEHGGSSGSKQNSDHNNGSFNLKALSGSSG------------YKFG-------------VLAKIVNYMKTRHQRGDTHPLTLEEILDET-------QHLDIGLKQKQWLMTEALVNNPKIEVVDG--KYAFKPKYNLKDKKALLRLLDNHDQRGLGGILLEDIEEGLPNSQKAVKAL---GDQILFVSRP-DKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVASIQRRKKPASQKKRRFKT--HNEHLAGVLKDYSDITPGK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D902-1", "uniprot_id": "T2EB_MOUSE", "id": "Q9D902-1", "name": "General transcription factor IIE subunit 2", "aln": "---------MDPSLLRDRELFKKRALSTPVVEKRAVPSESPSSSSS---KKKKAKVEHGGSSGSKQNSDHNNGSFNLKALSGSSG------------YKFG-------------VLAKIVNYMKTRHQRGDTHPLTLEEILDET-------QHLDIGLKQKQWLMTEALVNNPKIEVVDG--KYAFKPKYNLKDKKALLRLLDNHDQRGLGGILLEDIEEGLPNSQKAVKAL---GDQILFVSRP-DKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVASIQRRKKPASQKKRRFKT--HNEHLAGVLKDYSDITPGK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29084-1", "uniprot_id": "T2EB_HUMAN", "id": "P29084-1", "name": "Transcription initiation factor IIE subunit beta", "aln": "---------MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSS----KKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSG------------YKFG-------------VLAKIVNYMKTRHQRGDTHPLTLDEILDET-------QHLDIGLKQKQWLMTEALVNNPKIEVIDG--KYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKAL---GDQILFVNRP-DKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKT--HNEHLAGVLKDYSDITSSK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96881-1", "uniprot_id": "O96881_DROME", "id": "O96881-1", "name": "Transcription initiation factor IIE subunit beta", "aln": "---------MDPALLREREAFKKRAMATPTVEKKSKPDRPAPPPPS---DDSRRKMRPPNAPRLDATT--------YKTMSGSSQ------------YRFG-------------VLAKIVKFMRTRHQDGDDHPLTIDEILDET-------NQLDIGQSVKNWLASEALHNNPKVEASPCGTKFSFKPVYKIKDGKTLMRLLKQHDLKGLGGILLDDVQESLPHCEKVLKNR---SAEILFVVRPIDKKKILFYNDRTANFSVDDEFQKLWRSATVDAMDDAKIDEYLEKQGIRSMQDHGLKK--AIPKRKK-AANKKRQFKKPRDNEHLADVLEVYEDNTLTLKGVNPT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36145-1", "uniprot_id": "T2EB_YEAST", "id": "P36145-1", "name": "Transcription initiation factor IIE subunit beta", "aln": "------MSKNRDPLLANLNAFKSKVKSAPVIAPAKVGQKKTNDTVITIDGNTRKRTASERAQENTLNSAKNPVLVDIKKEAGSNSSNAISLDDDDDDEDFGSSPSKKVRPGSIAAAALQANQTDISKSHDSSKLLWATEYIQKKGKPVLVNELLDYLSMKKDDKVIELLKKLDRIEFDPKKGTFKYLSTYDVHSPSELLKLLR--SQVTFKGISCKDLKDGWPQCDETINQLEEDSKILVLRTKKDKTPRYVWYNSGGNLKCIDEEFVKMWENVQLP-----QFAELPRKLQDLGLKPASVDPATIKRQTKRVEVKKKRQRKGKITNTHMTGILKDYSHRV---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** : : **.:. ::*.: .. . . ..: : : .: * :**. ** . * .: :. .. : * * :::. : ** *: * * : ::* .: : . *.::. . *::** . : ** .*:::. *:.::.:: . ::: : .. : :::*. .:*:** *:*... : :: * .: .:: . . : *: :***: * * *::.:*: *.. . ", "identical_positions": 43, "similar_positions": 106, "identity": "12.29%" }, { "cls_id": "homologset.agr.SGD:S000001771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJM8-1", "uniprot_id": "A0A096MJM8_RAT", "id": "A0A096MJM8-1", "name": "", "aln": "---------------MERVWRAWDGQSVNENQPDSPGVAGMVVSWLSRAEWEQVTVYLFCDDQ----KLQQYALNRITVWRSRLGNELPLAVASTADLIRCKLLDVAGGLG-----TDELRLLYGMALVRFVN-LISERKSKSCNLPLKYLAHEVNIPEWIVELRHKLTHK-KMPHINDCRRGCYFVLHWLQKTFWSRQLEDSLKETWGMEEDQVEADEPE-EEETEIIIDDIIEEIPEFQDDDKGEELAVTDDANTKGNEEVASHPELSPRHKELYEKARELLVSYEEEQFKVLEKYRHLLQAIKVWNNLSPRVQGILEELKSISWENRDAVLDAFLDDGFLIPTYEQLAALQIEYEDGQTEVQKGEVTEPNSHKNIDLNEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTLGRTGIRPTYILRWTVELIVANTKTGRNARRFSAGQWEARRSWRLFNCSSTLDWPQVIEACLGSPCWASLQLLQVVFKAMGEVLPDEEQEKLLRVCSIYTQNGESGLAKAVEGSSSSSSSSSSTGKAPYTLDTLHQDLQPPATNCESEGNIQQKE-QDNLTDVKPEEEEKENVEEEEEEEKEEAEMEEEEK--EEEEEQEQEEHQEEEQEEEEEEEEEQKVFQDQMEADAEESDGLGEEEEVDEDEDDDEDDDYDDDDDDDEDGMDMGGFSLLQGSYVLENTRIMSQKREALQGSAWQLSSDDVRWGIFPIGRVPGQTEDPTELMLDNYDTMYLLDQPVLEHRLEPQKSKSSTLGLCCG-----SNNNGGVGNMEGLLWNQGQMHGLKAGLQLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BE28-1", "uniprot_id": "LAS1L_MOUSE", "id": "A2BE28-1", "name": "Ribosomal biogenesis protein LAS1L", "aln": "---------------MDRVWRAWDGQSFKENQPESPSARGIVVSWLSRAEWEQVTVYLFCDDH----KLQQYALNRITVWRSRLGNELPLAVASTADLVRCKLIDAAGTLG-----TDELRLLYGMALVRFVN-LISERKTKCSNLPLKYLAQEVNIPDWIVELRHNLTHK-KMPHINECRRGCYFVLNWLQKTYWSRQLEGSLKETWELDEDQLDAEDPE-EEEREIIADDVLEEIPEPQDDDKDEELAVEDDANTKGNEEVASHPEPSSRHKELYEKARELLVSYEEEQFKVLEKHRHLLQAIKVWNNLSPRVQCILEELKSISWENRDAVLDAFLDDGFLIPTFEQLAALQIEYEDGQTEVQKGEVTEPNSHKNIDLNEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTVGSTGIRPTYILRWTVELIVANTKTGRNARRFSASQWEARKSWRLFNCSATLDWPQVIESCLGSPCWASPQLLQVVFKAMGQVLPDEEQEKLLRVCSIYTQNGENGLAKAIEGSSSSS-----TGKAPYTLDTLHEDLQPPGTNCESEESIQQKE-QGNLKDVKQEEKKENEEEEKEEEEMEEEEEEEEEEKEEEEEEQEQEEHQEEEQEEEEEEEN-QKVFQDQMEADVEESDDVEEEEEVD-DEEEDEDDDYDDDE--EEDRMEVGAFSLAQGSSVFENTRTTSRKREALQGSAWQVSSEDVRWGTFPLGRLPGQTEDPAELMLDNYDTMYLLDQPVIEHRLEPQKSKSSTLSLCCGGSNTNSSSSSSSGNMEGLLWNQGQMHGLKAGLQLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4W2-1", "uniprot_id": "LAS1L_HUMAN", "id": "Q9Y4W2-1", "name": "Ribosomal biogenesis protein LAS1L", "aln": "MSWESGAGPGLGSQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFCDDH----KLQRYALNRITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLG-----TDELRLLYGMALVRFVN-LISERKTKFAKVPLKCLAQEVNIPDWIVDLRHELTHK-KMPHINDCRRGCYFVLDWLQKTYWCRQLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNPSPRVECVLAELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTDPKSHKNVDLNDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYILRWTVELIVANTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQ--EGSEASP-----IGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVK--------EEEKEEKEVLPDQVEEEEE--------------NDDQEEEEEDED---------------------------DEDDEE-----------EDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDPAELMLENYDTMYLLDQPVLEQRLEPSTCKTDTLGLSCG-VGSGNCSNSSSSNFEGLLWSQGQLHGLKTGLQLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36146-1", "uniprot_id": "LAS1_YEAST", "id": "P36146-1", "name": "Protein LAS1", "aln": "------------------------------------MIPPRIVPWRDFAELEELKLWFYPKSKGTIEDKRQRAVQRVQSYRLKGSQYLPHVVDSTAQITCAVLLDEKEACLGVHQDSIPIRLSYVMALIRFVNGLLDPTQQSQFAIPLHTLAAKIGLPSWFVDLRHWGTHERDLPGLEMLRWAANEALSWLYDHYWN---------------------------------DEELEDDRDDDDDDDDTGYGYRR------NDKLEKYMESLTKTLDKWKRLRNEFLEYK-----------------WVWEN----------------------------ANDSLITSSNFSGDNLVNYDAEKRKSSHASSSETMIRENLRQ------------WQELWK---LSIYHNVVLEKFFNNYDPL-------------LLKVLMLNLNN----FDWKVIEWVARN-------YRTQQDDSNITTILKRKFNAWKELQKRLLDVIINNLNNKNFKNKWQNWEKLIDEN-----------------------ASYLILYFCQSMLAKLETEKITGNSWRNK-----------------KRRKQIDSTVEIEAKLKEN--------------IDNLSLRFNEGE-----------------------------------------------IKLYDFIPAEKDSVPLKKEVSPALKADTNDILGDLASLKQRMSSFGTVGKKNKQEENRATPVKNWS--------------RVQNWKPKPFGVL-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* . ** :::.:::: ..: . :: *::*: :* : .: ** .* ***:: . *:* : :** * ***:**** *:. : . :**: ** ::.:*.*:*:*** **: .:* :: * .. .* ** . :* *: *: : :**... .::: .: : : ::: *: ::.*: .*:* :. *:.: : . ::*: : : .:.. ::. ::*: ** * : . : :.:**:::.: .: ::::: * :. :.. :* **. : : : : * * :* : ::..: : * ::: :: : . :.. :.* : : .: . . . ::: ..:: .. : : :*: :: . . :: : :.: * : . . : . . : :. :::* . * . * .: *: :.*:. . .. *...:.: ", "identical_positions": 77, "similar_positions": 211, "identity": "9.47%" }, { "cls_id": "homologset.agr.SGD:S000001776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1Z2-1", "uniprot_id": "TPPC3_RAT", "id": "Q5U1Z2-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEN-DEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFV-ELPDNHSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55013-1", "uniprot_id": "TPPC3_MOUSE", "id": "O55013-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEN-DEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFV-ELPDNHSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43617-1", "uniprot_id": "TPPC3_HUMAN", "id": "O43617-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEN-DEDVNKQLDKMGFNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFV-ELPDNHSSLIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZEX3-1", "uniprot_id": "D3ZEX3_RAT", "id": "D3ZEX3-1", "name": "Trafficking protein particle complex subunit", "aln": "-MSRPAHKRPEYH----------KINKDLFVLTYGALVAQLCKDYEK-DEDVNKYLDKMGYSIGTRLVEDFLARSCVRRCHSYSEIIDIIAQVAFKMYLGTTPSVTCHNSSRNEFSLILHKNPLAEFIEELPAGRSALCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDNVTEIGITFLKKVDDKKYRRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4KL14-1", "uniprot_id": "TPC3L_MOUSE", "id": "Q4KL14-1", "name": "Trafficking protein particle complex subunit 3-like protein", "aln": "-MSRPAHKRPEYH----------KINKDLFVLTYGALVAQLCKDYEK-DEDVNKYLDKMGYNIGTRLVEDFLARSCVRRCHSYSEIINIIAQVAFKMYLGITPSVTCHNSSRNEFSLILHKNPLAEFVEELPAGRSALCYCNLLCGIIRGALEMVHLAANVTFLQDRLKGDSVTEIGITFLKKLDEKKYRRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T215-1", "uniprot_id": "TPC3L_HUMAN", "id": "Q5T215-1", "name": "Trafficking protein particle complex subunit 3-like protein", "aln": "-MSRPAHRRPEYH----------KINKDLFVLTYGALVAQLCKDYEK-DEDVNQYLDKMGYGIGTRLVEDFLARSCVGRCHSYSEIIDIIAQVAFKMYLGITPSVTCNNSSKNEFSLILEKNPLVEFVEELPAGRSSLCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDSVTEIGITFLKKRDEKKYRGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSY8-1", "uniprot_id": "Q9VSY8_DROME", "id": "Q9VSY8-1", "name": "Trafficking protein particle complex subunit", "aln": "-MSRQASR-LDAK----------KVNSEFLTLTYGALVTQMLRDFEN-AEDVNKQLERIGYNMGMRLIEDFLARTSAPRCLEMRETADRIQQ-AFRIYLNIQPTISNWSPASDEFSLVFDSNPLTEFVELPPDLTN-LRYSAILSGCIRGALEMVQLEVQCWFVQDQLKGDNVTELRVKFVRRLEEVIPAGED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36149-1", "uniprot_id": "BET3_YEAST", "id": "P36149-1", "name": "Trafficking protein particle complex subunit BET3", "aln": "MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQDYERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNITPNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCDVWFVSDILRGDSQTEIKVKLNRILKDEIPIGED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . *:..:::.****::*:*: :*:*. :.**. * :*:.:* **:******: ** . : : : : **:::*. *.:: . : ***::..***.:*: . * *. :*.* ::*:****:: : *:.* *:**. **: : : : .: :.", "identical_positions": 52, "similar_positions": 69, "identity": "26.94%" }, { "cls_id": "homologset.agr.SGD:S000001778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BXW7-1", "uniprot_id": "HDHD5_HUMAN", "id": "Q9BXW7-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "------------------------------------------MAAWGCVAALGAARGLCWRAARAAAGLQGRPARRCYAVGPAQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELR----MAFPLLDMVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPP--YPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRGWAAPIRKLYAVGDNPMSDVYGANLFHQYLQKATHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNPQSTEPVLGGGEPPFHGHRDLCFSPGLMEASHVVNDVNEAVQLVFRKEGWALE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WM2-1", "uniprot_id": "HDHD5_MOUSE", "id": "Q91WM2-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "------------------------------------------MAALAGLGVLGAGRHLWKLPVRLSAGLQGCGPRRGYIAGSAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLRVPVVFVTNAGNILQHNKAQELSDLLRCKVDPDQVILSHSPMKLFLQYHSKQMLVSGQGPLVENARALGFQNVVTIDELR----LAFPELDMVDLQRRPKTMRL-RSDFPAIEGVLLLGEPVRWETNLQLIMDVLLSNGHPGTGLATAP--YPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYRKITGNELKYEGLMGKPSILTYQYAEDVIRQQAERRGWAAPIRKLYAIGDNPMSDVYGANLFHQYLQMANR-GEEEQQTGGQQKQRPSATQSCASILVCTGIYSSQDPGSQVPPPGRRELPFHGHRDFSFSPGLLEASHIVHDVNEAVQLVFHQEGWA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQB6-1", "uniprot_id": "D3ZQB6_RAT", "id": "D3ZQB6-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "aln": "MVGLPPPRGSARAAADWLLGCARGGGSRVGETRSLRVRATSAMAALARLGVLGPGRCLWKLPVRLSAEFQGYGPRRGYVADRAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLQVPVVFVTNAGNILQRDKAQELSALLECKVDPDQVILSHSPMKLFLQYHNKRMLVSGQGPLVENARALGFQNVVTVDDLR----IAFPELDMVDLQRRPKTMRP-RSDFPAIEGVLLLGEPVRWETNLQLITDVLLSNGHPGAGLATAP--YPHLPVLASNMDLLWMAEASMPRFGHGTFLLCLETIYRKITGHELKYEGLMGKPSILTYRYAEEVIRQQAERRGWAAPIRKLYAIG----------TCKWQMVERRSN-GLMDKRSSG--LQQPGAVLPSWCALVYT-VLRTQAP---------KHLLLEGQS--SHSTGTETSASVQSS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36151-1", "uniprot_id": "YK50_YEAST", "id": "P36151-1", "name": "Mitochondrial hydrolase YKR070W", "aln": "--------------------------------------------------MIG---------------------KRFFQT----TSKKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN----KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNKYSR-ILAVGTPSVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENGMLNTLRNEKSGKPSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNGEPLQDY-TLGKPTKLTYDFAHHVLIDWEKRLSGKIGQSVKQKLP-----------LLGTKPSTSPFHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGDD-----------------------LKECKPTLIVNDVFDAVTKTLEKYA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* : . . .:.: :******.**:: *..* .*: * .. ::* :::**.*.: :: ::: :* * .*.. *:* **:* * : : :.: :*. * .: *.. **::** :: * .: * : : ::.**::.:* * :.:*:* *.: *:. * . * :*: ** **** .: ***:*:* * :. :* ::.*. *: :***: *** :*..:: :* . : . . . . . ** * : .: : . ", "identical_positions": 73, "similar_positions": 107, "identity": "15.5%" }, { "cls_id": "homologset.agr.SGD:S000001779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XID1-1", "uniprot_id": "CPIN1_RAT", "id": "Q5XID1-1", "name": "Anamorsin", "aln": "MAEFGISPGQLVAVFCDKSSSEEALKKLVGRVQGLTGSEGQVFVENITQLLQSAHKESSFDVILSGIVPGSTSLHSPEALADMARILRPGGCLFLKEPVETTGVNNDKIKTASKLCSALTLSGLVEIKELQREALSPEEAQSMQEHLGYHSDSLLSVHVTGKKPNFEVGSSSQLKL-LHKKSS-SVKPVVDPATAKLWTLSANDMEDDSMDLIDSD--------------ELLDPEDLKKPDPAS---LKAPSCGEG--KKRKACKNCTCGLAEELEKEQSKAQ---------------------SSQPKSACGNCYLGDAFRCANCPYLGMPAFKPGEQVLLSSSNLQDA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WTY4-1", "uniprot_id": "CPIN1_MOUSE", "id": "Q8WTY4-1", "name": "Anamorsin", "aln": "MEEFGISPGQLVAVFWDKSSPEEALKKLVARLQELTGSEGQVFMENVTQLLQSSHKESSFDVILSGVVPGSTSLHSAEVLAEMARILRPGGCLFLKEPVETAEVNNDKMKTASKLCSALTLSGLVEIKELQREALSPEEVQSVQEHLGYHSDSLRSVRVTGKKPNFEVGSSSQLKL-PNKKSS-SVKPVVDPAAAKLWTLSANDMEDDSVDLIDSD--------------ELLDPEDLKRPDPAS---LKAPSCGEG--KKRKACKNCTCGLAEELEREQSKAQ---------------------SSQPKSACGNCYLGDAFRCANCPYLGMPAFKPGEQVLLSNSNLQDA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FI81-1", "uniprot_id": "CPIN1_HUMAN", "id": "Q6FI81-1", "name": "Anamorsin", "aln": "MADFGISAGQFVAVVWDKSSPVEALKGLVDKLQALTGNEGRVSVENIKQLLQSAHKESSFDIILSGLVPGSTTLHSAEILAEIARILRPGGCLFLKEPVETAVDNNSKVKTASKLCSALTLSGLVEVKELQREPLTPEEVQSVREHLGHESDNLLFVQITGKKPNFEVGSSRQLKLSITKKSSPSVKPAVDPAAAKLWTLSANDMEDDSMDLIDSD--------------ELLDPEDLKKPDPAS---LRAASCGEG--KKRKACKNCTCGLAEELEKEKSREQM--------------------SSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLSDSNLHDA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZB3-1", "uniprot_id": "CPIN1_DANRE", "id": "Q6AZB3-1", "name": "Anamorsin", "aln": "MADLGLQKGKRVLLIWTQPSSSSALKQFAESIAAVVGDQSLVSLENSERLLLSSHNASSYDCVLSGLLTDSSLIHSSEMLVEMARVMKPGGTLVLEEPVTGSEDTG--VRTAEKLMSAIKLAGLVSVTEVKTEPLSPKAAAALTERTGFSGNTLSRVRMTASKPDFEVGSSTQLKLSFGKKKTTTVKPALDPGTAQKWTLSANDMDDDDVDLVDSD--------------ALLDADDLKKPDPSS---LKA-SCGDDSKKKKKACKNCTCGLAEELEQESKAAQK--------------------ASQPKSACGNCYLGDAFRCGSCPYLGMPAFKPGEKVLLANTDIADK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Y2-1", "uniprot_id": "DRE2_DROME", "id": "Q9V3Y2-1", "name": "Anamorsin homolog", "aln": "MENF--KGLQKSLYIWTDS---ADLDKRVEQLKAATG--GDVALENVHRLSFSSYANSSFDLIVI------ECAQLTDSYVKLLHMLKPSGKLHLVSYIG----------PAASLLQEIKLSGFINCREDSPDALTAE------------------------KPGYETGSS--ARLSFAKKNA---------SAVNVWKISGDDEE-----LIDEE--------------ELLDEEDKQKPDPAG---LRVCSTTGK----RKACKNCSCGLAEELETEKQSQKA--------------------TENAKSSCGNCYLGDAFRCSTCPYLGMPAFKPGEKVQLADNLLKSDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36152-1", "uniprot_id": "DRE2_YEAST", "id": "P36152-1", "name": "Fe-S cluster assembly protein DRE2", "aln": "MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTP--EAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDS--ISDDL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . . : * : . .: . : . : ::*.* * . : . . . : .*. : : :. : :..: : : : : : ...: :: :: * :. : : :****:*:**: *: * * . : : ..**.* *******. *****:******: : * . : . ", "identical_positions": 39, "similar_positions": 69, "identity": "11.08%" }, { "cls_id": "homologset.agr.SGD:S000001780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6H7-1", "uniprot_id": "A0A8I6A6H7_RAT", "id": "A0A8I6A6H7-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "---------------------------------------------------------------------------------------------------------------------MTTTPRSHRTKLR--LPECHAITSFSLESFRAGKALDTAILGGILQL-------------------ILLSSQKATR--SRMEPEAP------------------------------------CPASIPSVER-------------KFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVTVVTTERAKHFYSP----------------------QDVPVT-------------------LYSDADEWEMWKRRSDPVLHIDLRRWADLMVVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVGQLK-AFGYVEIPCVSKKLV--CGDQGLGAMAEVEIIVAKVKDVLFQHGGIQQS-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZB2-1", "uniprot_id": "COAC_MOUSE", "id": "Q8BZB2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKAP------------------------------------CPAAVPSEER-------------KFRVLVGVTGSVAALKLPLLVSKLLDVPG---LEVTVVTTERAKHFYSP----------------------QDVPVT-------------------LYSDADEWEMWKRRSDPVLHIDLRRWADLMLVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVAQLK-AFGYVEIPCVSKKLV--CGDQGLGAMAEVETIVAKVQAVLSQHGSIQQS-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CD2-1", "uniprot_id": "COAC_HUMAN", "id": "Q96CD2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKAS------------------------------------CPAAAPLMER-------------KFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVAVVTTERAKHFYSP----------------------QDIPVT-------------------LYSDADEWEIWKSRSDPVLHIDLRRWADLLLVAPLDANTLGKVASGICDNLLTCVMRAWDRSKPLLFCPAMNTAMWEHPITAQQVDQLK-AFGYVEIPCVAKKLV--CGDEGLGAMAEVGTIVDKVKEVLFQHSGFQQS-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36024-1", "uniprot_id": "SIS2_YEAST", "id": "P36024-1", "name": "Phosphopantothenoylcysteine decarboxylase subunit SIS2", "aln": "MTAVASTSGKQDADHNQSIECPRFSRGQKEILLDHEDAKGKDSIINSPVSGRQSISPTLSNATTTTTKSIMNATGTSGAVVSNTPEPGLKRVPAVTFSDLKQQQKQDSLTQLKNDSERTKSPNSNPAPVSNSIPGNHAVIPNHTNTSRTTQLSGSPLVNEMKDYDPKKKDSALKIVDTMKPDKIMATSTPISRENNKVTAKAPTSITLRKEDAQDQANNVSGQINVRSTPEETPVKQSVIPSIIPKRENSKNLDPRLPQDDGKLHVLFGATGSLSVFKIKPMIKKLEEIYGRDRISIQVILTQSATQFFEQRYTKKIIKSSEKLNKMSQYESTPATPVTPTPGQCNMAQVVELPPHIQLWTDQDEWDAWKQRTDPVLHIELRRWADILVVAPLTANTLSKIALGLCDNLLTSVIRAWNPSYPILLAPSMVSSTFNSMMTKKQLQTIKEEMSWVTVFKPSEKVMDINGDIGLGGMMDWNEIVNKIVMKLGGYPKNNEEEDDDEDEEEDDDEEEDTEDKNENNNDDDDDDDDDDDDDDDDDDDDDDDDEDEDEAETPGIIDKHQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*. *: * *. *::**.*.***::.:*: ::.** :: * :.: *: *: *.:*:. *** *::* ***: ** *:******:******:::**** ****.*:* *:******.*:***: . *:*:.*:* :: :: :* :*: :* :.:* : ::*:: ** ***.* : ** *: * : ::. ", "identical_positions": 82, "similar_positions": 71, "identity": "14.59%" }, { "cls_id": "homologset.agr.SGD:S000001782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M1X1-1", "uniprot_id": "A0ABK0M1X1_RAT", "id": "A0ABK0M1X1-1", "name": "", "aln": "--------------------------MAVEEATITVRLIRSFEHRNFKPVVYHRVNLHQTVKEFIIFLKQDVPSRTSLPPPLRNYKYDTLKILHQAHKAKTNELVLGLEDDDTLLLKED---RTLKDSGVGAVSASLDISAQKFPICQRQFCAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRW3-1", "uniprot_id": "CB076_MOUSE", "id": "Q9CRW3-1", "name": "UPF0538 protein C2orf76 homolog", "aln": "--------------------------MAAEEATLTVRLIRSFEHRNFKPVVYHGVNLHQTVKEFIIFLKQDVPLRTSLPPPLRNYKYDTLKILHQAHKAKTNELVLGLEDDDTLLLKED---RTLKDSGVASETEIAFFCGEDYKRYKANPISSW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KRA6-1", "uniprot_id": "CB076_HUMAN", "id": "Q3KRA6-1", "name": "UPF0538 protein C2orf76", "aln": "--------------------------MAPGEVTITVRLIRSFEHRNFKPVVYHGVNLDQTVKEFIVFLKQDIPLRTNLPPPFRNYKYDALKIIHQAHKSKTNELVLSLEDDERLLLKED---STLKAAGIASETEIAFFCEEDYKNYKANPISSW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66IB8-1", "uniprot_id": "CB076_DANRE", "id": "Q66IB8-1", "name": "UPF0538 protein C2orf76 homolog", "aln": "--------------------------MMCDRAVLTVRLVRSFEHRNFKPLVFKDVNLDQTVDEFISFVKQDISVRAGLPPPFRKFDYDTLKIIHQAHGAKTNELVMSLEDDEKLILREG---CRLRACGVANETELAFFKMTDYIKFKADPHSEW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36154-1", "uniprot_id": "AIM29_YEAST", "id": "P36154-1", "name": "Altered inheritance rate of mitochondria protein 29", "aln": "MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPYRNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTVNLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*:*:::** :**.* :* : :* :.. : : : . . *:*: .:*:*** :** :** :**:.::.*: * * *: : : .: : : ", "identical_positions": 25, "similar_positions": 41, "identity": "16.13%" }, { "cls_id": "homologset.agr.SGD:S000001787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGS5-1", "uniprot_id": "RNZ2_RAT", "id": "Q8CGS5-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALRSLLRPLG--LRTMSQG------SARRPRPPKDPLRHLRTREKRGPGWGPGGPNTVYLQVVAAGGRDAAAALYVFSEYNRYLFNCGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLCGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIDL-AVRPHSAPEYKDETMTVYQVPIHSERRCGEQEPSRSPKRSPNRLSPKQSSSDPGSAENGQCLPEGSSAGVNGKAWGRDPSLVVAFVCKLHLRKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITYE-GREIAAEELCTPPDPGLVFIVVECPDEGFIQPICEN-DTFQRYQGEADAPVAVVVHIAPESVLIDSRYQQWMER-----FGPDTQHLILNENCPSVHN-LRSHKIQTQLSLIHPDIFPQLTSFHSKE--------------EGSTFSLPTVRG--------ECLLKYHVRPKREWQRDTTLDCNTDEFIAEALELPNFQESVEEYRKNMQASPAPAEKRS-------------------QYPEIVFLGTGSAIPMKIRNVSSTLVNLSP--------DKSVLLDCGEGTFGQLCRHYG-QQIDRVLCNLTAVFVSHLHADHHTGLLNILLQREHALA-------------SLGKPFQPLLVVAPTQLRAWLQQY-------------------HNQCQEILHHISMIPAKCLQKGAEVPSPPVERLISLLLETCDLQEFQTCLVRHCKHAFGCALVHSSG-------WKVVYSGDTMP--CEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAIGVGMRMNAEFIMLNHFSQRYAKIP-LFSPD--FNEKVGIAFDHMKVCFGDFPTVPKLIPPLKALFADDIEEMVERREKRELRLVRAALLT-QQADSSEDREPHQKRAHSEEPHSPQSKKVRAQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y81-1", "uniprot_id": "RNZ2_MOUSE", "id": "Q80Y81-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALRSLLRPLG--LRTMSQG------SARRPRPSKDPLRHLRTREKRGP--GPGGPNTVYLQVVAAGGRDAGAALYVFSEYNRYLFNCGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLCGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIEL-AVRPHSAPEYKDETMTVYQVPIHSERRCGKQQPSQSPRTSPNRLSPKQSS-DSGSAENGQCPPEDSSAGANRKAWGRDPSLVVAFVCKLHLRKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITYE-GREIAAEELCTPPDPGLVFIVVECPDEGFILPICEN-DTFKRYQAEADAPVALVVHIAPESVLIDSRYQQWMER-----FGPDTQHLILNENCPSVHN-LRSHKIQTQLSLIHPDIFPQLTSFYSKE--------------EGSTLSVPTVRG--------ECLLKYQLRPKREWQRDTTLDCNTDEFIAEALELPSFQESVEEYRKNVQENPAPAEKRS-------------------QYPEIVFLGTGSAIPMKIRNVSSTLVNLSP--------DKSVLLDCGEGTFGQLCRHYG-QQIDRVLCSLTAVFVSHLHADHHTGLLNILLQREHALA-------------SLGKPFQPLLVVAPTQLRAWLQQY-------------------HNHCQEILHHVSMIPAKCLQKGAEVSNTTLERLISLLLETCDLEEFQTCLVRHCKHAFGCALVHSSG-------WKVVYSGDTMP--CEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAINVGMRMNAEFIMLNHFSQRYAKIP-LFSPD--FNEKVGIAFDHMKVCFGDFPTVPKLIPPLKALFAGDIEEMVERREKRELRLVRAALLT-QQADSPEDREPQQKRAHTDEPHSPQSKKESVANTLGARV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ52-1", "uniprot_id": "RNZ2_HUMAN", "id": "Q9BQ52-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALCSLLRSAA--GRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIEL-AVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSS-DSESNENEPHLP----HGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHE-GREILAEELCTPPDPGAAFVVVECPDESFIQPICEN-ATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMER-----FGPDTQHLVLNENCASVHN-LRSHKIQTQLNLIHPDIFPLLTSFRCKK--------------EGPTLSVPMVQG--------ECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRS-------------------QYPEIIFLGTGSAIPMKIRNVSATLVNISP--------DTSLLLDCGEGTFGQLCRHYG-DQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALA-------------SLGKPLHPLLVVAPNQLKAWLQQY-------------------HNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSG-------WKVVYSGDTMP--CEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVP-LFSPN--FSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEE---PQAKKVRAQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MKW7-1", "uniprot_id": "RNZ_DROME", "id": "Q8MKW7-1", "name": "Ribonuclease Z, mitochondrial", "aln": "MYLVKSAGSPIYRTLRTLTTSN-LMAATIASAKDPLTGPRYEREPNVLRKKLASVVPGTVNLQVLGSGANGAPAAVYLFTDQARYLFNCGEGTQRLAHEHKTRLSRLEQIFLT-QNTWASCGGLPGLTLTIQDAGVRDIGLHGPPHLGSMLQSMRRFVVLKNLQVR-PNDCSEGACFEDSILKVDSLPLINS-----EDPTKS---------------------------------------------VINYICQLKPRAGALNLVKCVEQGVPPG-----PLLGQLKNGNDITLPDGKVVRSVDVTEASETALSFVFLDVPSENYLPALLTHGKRLKKLGEEKLTEVALVVHFTPYHISSRQVYKDFVVES----FSSEAQHIYLSSPLNQFSGYAAAHRIQHQLHQLAPQVFPLLGEQLSCQSQTLSLNLKKTKLDEADSEDKANAKANETEEQGVVAMTNYHLRPRKGLDRTLESKLTPEEYVKETHAVPGFLELLAKFKEEYS---FPDNSAD-------------------SYPKIIFLGTGSCIPNKTRNVSSILIRTAI--------DAYVLLDCGEGTYGQIVRLYGHEKGQLILRQLQAIYVSHLHADHHIGLIGLLRERR-----------------QLKPRADPLILLAPRQIEPWLEFY-------------------NRQIETVEDAYTLVGNGELLA-SPLSGEQVERLG--------ITSISTCLVRHCPNSFGISLTLAAKHNSEP--VKITYSGDTMP--CQDLIDLGRDSTVLIHEATMEDDLEEEARLKTHSTVSQAIQQGRNMNARHTILTHFSQRYAKCPRLPSDE--DMQRVAIAFDNMEVTIEDLQHYHKLYPALFAMYAEYTEELEQRAVKRELKQERKRKLAET--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36159-1", "uniprot_id": "RNZ_YEAST", "id": "P36159-1", "name": "Ribonuclease Z", "aln": "MFTFIPITHPTS---------------------------------------------DTKHPLLLVQSAHG----------EKYFFGKIGEGSQRSLTENKIRISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRYFVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVFDSFQKGVLRSIVAKMFPKHAPTDRYDPSSD-PHLNVELPDLDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVPKG-----PLFAKLTKGQTITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEK------FKDYDCAELGMVYYFLGDEVTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSALTTLKLKALQVNNYNLPKTDRVFSKDFYDR------FDTPLSRGTSMCKSQEEPLNTIIEKDNIHIFSQNKTVTFEPFRMNEEPMKCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQLHVDNFNNSAEKKKHVEIITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLDAGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETSYIYVVTPWQYHKFVNEWLVLENKEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEILKENSNQESNRKLELDRDSSYRDVDLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFRMDENNEHNTFKVSYSGDTRPNIEKFSLEIGYNSDLLIHEATLENQLLEDAVKKKHCTINEAIGVSNKMNARKLILTHFSQRYPKLPQLDNNIDVMAREFCFAFDSMIVDYEKIGEQQRIFPLLNKAFVEEKEEEEDVDDVESVQDLEVKLKKHKKN------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . . . .* :: .... :: : *** ** *:* ::::*.:**** . *:. *** *: **: : * . * .: . : : : . ::*. : * .. : .. * : .: * : : :. : *:* * *::. :..*: ** * : . :: .:.:: *.: :: .: : : :.:* :: : . :: :. : : .. . . : :* : : : . : . . :. : :: .:. . : : . :.. . * . . .: :*: *****.:* * *** : *:. . : ::**.**.* * : * :. . :: * :::******** *: .:* : . . ::: :: :: . : : . : .. * : :.** . ** ::. ::. *: ***** * : : :* :: :******:*: * *:* *.*.* .:** . .***. :*.******.* * * . ... .*** * * .: :: * * :. ** : ..:: . ", "identical_positions": 119, "similar_positions": 212, "identity": "12.57%" }, { "cls_id": "homologset.agr.SGD:S000001788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18155-1", "uniprot_id": "MTDC_MOUSE", "id": "P18155-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "-MASVSLLSALAVRL-------------LRPTHGCHPRLQP-FHLAAVRNEAVVISGRKLAQQIKQEVQQEVEEWVASGNKR-PHLSVILVGDNPASHSYVLNKTRAAAEVG--------------------------------------------INSETIVKPASVSEEELLNSIRKLNNDENVDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEIIKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN--RVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRP-EELEVFKSKQRGVATN------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GID3-1", "uniprot_id": "A0A8I6GID3_RAT", "id": "A0A8I6GID3-1", "name": "methenyltetrahydrofolate cyclohydrolase", "aln": "-MVSVS-LSALAVRL-------------LRPTHGCHSRLQS-FHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGDNPASHSYVLNKTRAAAEVAGSWIGHSSQLRQKGRKTPGARPLTVTRADAGTSKPAASRLMSYGINSETIVKPASVSEEELLNSIRTLNDDENVDGLLVQLPLPEHIDERKICNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEILKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRHTPKEQLKKHTILADIVISAAGIPNLITADMIKEGATVIDVGIN--RVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRP-EELEVLKSTQRGVATN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13995-1", "uniprot_id": "MTDC_HUMAN", "id": "P13995-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "-MAATSLMSALAARL-------------LQPAHSCSLRLRP-FHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGENPASHSYVLNKTRAAAVVG--------------------------------------------INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEIIKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN--RVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRL-EEREVLKSKELGVATN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YZG8-1", "uniprot_id": "MTD2L_MOUSE", "id": "D3YZG8-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGFSLLRGRLGRGP---------VRAPGVAERAWRG-FGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRR-PHLSIILVGDNPASHTYVRNKIKAASAVG--------------------------------------------ICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGIN--YIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUA0-1", "uniprot_id": "MTD2L_RAT", "id": "D3ZUA0-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGLSLLRGRLGRGP---------ARAPGVAERAWRG-FGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVG--------------------------------------------ICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGIN--YVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNITY------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H903-4", "uniprot_id": "MTD2L_HUMAN", "id": "Q9H903-4", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRG-FRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVG--------------------------------------------ICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRTGIQT---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGIN--YVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEG5-1", "uniprot_id": "A0A8M2BEG5_DANRE", "id": "A0A8M2BEG5-1", "name": "methenyltetrahydrofolate cyclohydrolase", "aln": "MAAPG-ALTVNYTRIQTLMSCFTYCRRPKRWINLKTVNRRSSFCQSLKRHVATVVSGAELARQIHKEVQSDIAKLVAEGNRR-PHLSVILVGDDHASHTYVRNKTRTASLLG--------------------------------------------MSSSTIFRPSSVSQEEMLELIDKFNRDRNISGLLVQLPLPEHINERAICNAVAPEKDVDGFHIVNIGKLCLDQ---------RCMIPATAAAVWEIIRRTGLET---------VGKNVLVVGRSKNVGMPIAMLLHSDRKHERSGGDATVIMAHRCTPLPRLKELARLADIVIAAAGVPHLITADMVKEGAAVIDVGIN--RMQDPVTGKSRLVGDVDFEAVKEKAGFITPVPGGVGPMTIAMLQANTLVTEEKKIVEWAETRLCLLLASGSGSDAGHYTGMAKKDWIHWSSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04448-1", "uniprot_id": "MTDC_DROME", "id": "Q04448-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "--------------------------------------------MRFTSNMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPK-PHLTAVIVGEDPASEKYVANKMVACREVG--------------------------------------------ISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTALDM---------EANIPATPLGVKRLLEHMKIET---------LGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGIN--RIKDESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARKQFDDRKSS-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02046-1", "uniprot_id": "MTD1_YEAST", "id": "Q02046-1", "name": "Methylenetetrahydrofolate dehydrogenase [NAD(+)]", "aln": "-----------------------------------------------MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMG--------------------------------------------FRYDLRVIE---DKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTG---KVTIAMLLRNMLRLVRNVELSKEK--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :*. .. :: : : * * .:..:: *:. *. . :. :. : . :: : : * * : *::* :*: : ::: : : : :***:*:: : . : . :*.*. .: .::. : . *:: :* .**: *. *:* ** * .: * . : *:: *. : : ::: . . : *:: *. .*:.* :*:*** * : .: ", "identical_positions": 38, "similar_positions": 96, "identity": "8.46%" }, { "cls_id": "homologset.agr.SGD:S000001789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ80-1", "uniprot_id": "RPF2_MOUSE", "id": "Q9JJ80-1", "name": "Ribosome production factor 2 homolog", "aln": "MDALDKVLKPKTKRAKRFLEKREPKLTENIKNAMLIKGGNANATVTQVLRDMYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEK-FVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDFRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGK--------VYFRSYKLLLKKS---GCRTPRIELEEMGPSLDLVMRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKMKGLKKRPAENGVDDQGKKSKRIKKN-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7ENM1-1", "uniprot_id": "F7ENM1_RAT", "id": "F7ENM1-1", "name": "Ribosome production factor 2 homolog", "aln": "MDALDKVLKPKTKRAKRFLEKREPKLSENIKNAMLIKGGNANATVTQVLRDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEK-FVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDYRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGK--------VYFRSYKLLLKKS---GCRTPRIELEEMGPSLDLVVRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKVKGLKKRPAENGVEDQGKKSKRIKKS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H7B2-1", "uniprot_id": "RPF2_HUMAN", "id": "Q9H7B2-1", "name": "Ribosome production factor 2 homolog", "aln": "MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEN-FVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGK--------IYFRSYKLLLKKS---GCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKSKRIKKN-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEB3-1", "uniprot_id": "RPF2_DROME", "id": "Q9VEB3-1", "name": "Ribosome production factor 2 homolog", "aln": "-MSLLRIRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKNDITPFDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKR-YQAISEFKNEKIGACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMN-------ILMRSYRILLKKS---GQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGNTKGRVHLGKQQTGSIQTRRVKALRKTPEEKKENRQRKKVALKAAAA----------EALASQGNNPFSS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36160-1", "uniprot_id": "RPF2_YEAST", "id": "P36160-1", "name": "Ribosome biogenesis protein RPF2", "aln": "---MIRTVKPKNARAKRALVKREAKLVENVKQALFIPGQSCNKNLHDIMVDLSALKKPDMKRFNRKNDIHPFEDMSPLEFFSEKNDCSLMVLMTSSKKRKNNMTFIRTFGYKIYDMIELMVADNFKLLSDFKKLTFTVGLKPMFTFQGAAFDTHPVYKQIKSLFLDFFRGESTDLQDVAGLQHVISMTIQGDFQDGEPLPNVLFRVYKLKSYKSDQGGKRLPRIELVEIGPRLDFKIGRIHTPSPDMVTEAHKKPKQLEMKTKKNVELDIMGDKLGRIHMGKQDLGKLQTRKMKGLKSKFDQGTEEGDGEVDEDYEDEASYSDDGQEYEEEFVSATDIEPSAKRQKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ***. :.*: * **.:* *. : ::: * ... .: : *: ***** ::** **:* :.***:: *.*.:*: : : .*** :*: : * : .: **:** : : :.::*. . ** : * * : ::::.*::* *: ... : *:::*: :* .. : :* *:: ** * * ***** *:** *: : * : .* *: . : * ** *: .:**:. * :* . **:*: **: ..:***::*.*:. : : . : ", "identical_positions": 83, "similar_positions": 104, "identity": "23.92%" }, { "cls_id": "homologset.agr.SGD:S000001790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8B2-1", "uniprot_id": "D3Z8B2_RAT", "id": "D3Z8B2-1", "name": "Nuclear pore complex protein Nup133", "aln": "MFPGVSSPRTPGPGTRRGPLVGIGPSTTPR-ASRRGLSLGSAVSSPVLFSPVGRRSSVSSRGTPTRIFPYHSISESVNYDVRVFGSSLPVKIMEALAMAEADD-QLSVHVDEGGWACLVCKEKLLVWKIAMSPVT--------------KLSVCKDLQLPPSDFHWSADLVALSYAATSGEVHSVQAVSVMVATKEGSIRYWPSLAREDTYSDTSVDLGGEKVCRFLTAVQGGSFILSSVGSQLVRLIPEGSG--KIHQHVLPQGQGMLSGIGRRVSSLFGILSPTSD------LMLASVLWDRGNSSFYTLTSSNISKWELDDSSEKQVYSWDMHRALKESITDAIWGSESN-YEAIKEGVSIQYLDLKQNCDGLLILAAAWHLGDSPCLVYYSVITVEDNGNQMSDAVTVEVTQYNPPFQSED-LVACRLMVPDFPSQMTYLYMESAVFVCSTG--TGKVSLPQEKIVFDTQGDGILGAGSCGGVPILFSRNSGLVSVTPRESMSLLAEGLEESLASSGGGRGSESMVFETT-KNDTAAHE------------------DKTKLLKTAFLQYCRKDLGRAQMMADELFSSHTDLESDPE------LDKAVTQISVDLIDDYPASDPRWAESVPQEAPG----LSNTSLIVLHQLEDKMKAHCLLVDFLHQVGLFRRLDSYPIRGTPMTTR-LLLCEHAEKLSAAITLKNHHSRLPDLVNAAILLALNKRECEVPPSLTPADVFFREVSQVDTICECLLEHEEQVLRDVALVSQEWAEVAIDVNTVLKDMLQAAAHYRLNKGSMYSREEPLGKEPEYVPWTATSGPSGIRTVIMRQHGIILKT-VYPQADSNLRSIVMEQLVALIDCFLDSYVSQLKSLEKSSDQERYSSLEVEYLQKRSELLSPLLTLGQYPWAASLAEKYCDFDILVQMCEQTD--NQARLQRYMTQFADQ--NFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQA----HEHLSWLHEINSQELEKAHTTLLGLANMETRYFAKKKTLLGLSKLAALASDLSEDTLQEKIEAMAEQERFLLHQETLPEQLLTERQLSLSAMPVLT-----APQLISLYICEENRRANEYDFKKALDLLEYIDEEE-----------DVNIDDLKLEILCRALQRD---DWSGSDGRDDPIEVSKDSVFVKILQKLIKDGVQLSEYLPEVKDLLQA------------------------EQLGSLKSNSYFEFVLKANYEYYVQGQM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0G9-1", "uniprot_id": "NU133_MOUSE", "id": "Q8R0G9-1", "name": "Nuclear pore complex protein Nup133", "aln": "MFPSVSSPRTPGPGTRRGPLVGIGPTSTPR-ASRRGLSLGSAVNSPVLFSPAGRRSSVSSRGTPTRIFPHHSISESVNYDVRVFGSSLPVKIMEALTMAEADE-QLSVHVDEGGWACLVCTEKLLIWKIAVSPVT--------------KLSVCKELQLPPSDFHGSADLVALSYAATSGEVHSVQAVSVMVATKEGSIRYWPSLAREDTYSDTCVDLGGEKMCRFLTAVQGGSFILSSVGSQLVRLIPESSG--KIHQHVLPQGQGMLSGIGRRVSSLFGILSPTSD------LMLASVLWDRGGSSFYTLTSSNISKWELDDSSEKQVHSWDVHRTLKESITDAVWGSESN-YEAIKEGVNIQYLDLKQNCDGLLILAAAWHLGDSPCLVYYSVITVEDNGNQMSDAVTVEVTQYNPPFQSED-LIACRLMVPNFSSQMTYLYMENAVFVCSTG--TGKFSLPQEKIVFDTQGDGILGAGSCAGVPILFSRNSGLVSVTPRENVSLLAEDLEESLTSSVGGRGSESMVFETTTKNETVAHE------------------DKTKLLKAAFLQYCRKDLGRAQIMADELFSSHTDLDSDPE------LDKAVTQISVDLIDDYPASDPRWAESVPQEAPG----LSNTSLIILHQLEDKMKAHCLLVDFLHQVGLFRRLSSYPIRGTPMSTR-LLLCEHAEKLSAAITLKNHHSRLPDLVNSAILLALNKRECEVPNSLTPADVFFREVSQVDTICECLLEHEEQVLREVALVSQEWAEVAIDVNTVLKDMLQAATHYRLNKSSMYSQEEVLGKEPEYVPWTATSGPSGIRTAVMRQHGIILKM-VYPQADSKLRNVVMEQLVALIDCFLDSYVSQLKSLEKSSDQERYSSLEVEYLQKRSELLSPLLTLGQYPWAASLAEKYCDFDILVQMCEQTD--NQARLQRYMTQFADQ--NFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQA----HEHLSWLHEINSQELEKAHTTLLGLANMETRYFAKKKTLLGLSKLAALASDISEDRLQEKIEAMAEQERFLLHQETLPEQLLTERQLSLSAMPVLT-----APQLISLYICDENRRANEYDFKKALDLLEYIDEEE-----------DVSIDDLKLEILCRALQRD---DWSGSDGKDDPIEVSKDSVFVKILQKLIKDGIQLSEYLPEVTDLLRA------------------------EQLGSLKSNSYFEFVLKANYEYYVQGQM------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUM0-1", "uniprot_id": "NU133_HUMAN", "id": "Q8WUM0-1", "name": "Nuclear pore complex protein Nup133", "aln": "MFPAAPSPRTPGTGSRRGPLAGLGPGSTPRTASRKGLPLGSAVSSPVLFSPVGRRSSLSSRGTPTRMFPHHSITESVNYDVKTFGSSLPVKVMEALTLAEVDD-QLTINIDEGGWACLVCKEKLIIWKIALSPIT--------------KLSVCKELQLPPSDFHWSADLVALSYSSPSGEAHSTQAVAVMVATREGSIRYWPSLAGEDTYTEAFVDSGGDKTYSFLTAVQGGSFILSSSGSQLIRLIPESSG--KIHQHILPQGQGMLSGIGRKVSSLFGILSPSSD------LTLSSVLWDRERSSFYSLTSSNISKWELDDSSEKHAYSWDINRALKENITDAIWGSESN-YEAIKEGVNIRYLDLKQNCDGLVILAAAWHSADNPCLIYYSLITIEDNGCQMSDAVTVEVTQYNPPFQSED-LILCQLTVPNFSNQTAYLYNESAVYVCSTG--TGKFSLPQEKIVFNAQGDSVLGAGACGGVPIIFSRNSGLVSITSRENVSILAEDLEGSLASSVAGPNSESMIFETTTKNETIAQE------------------DKIKLLKAAFLQYCRKDLGHAQMVVDELFSSHSDLDSDSE------LDRAVTQISVDLMDDYPASDPRWAESVPEEAPG----FSNTSLIILHQLEDKMKAHSFLMDFIHQVGLFGRLGSFPVRGTPMATR-LLLCEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPSNLTPADVFFREVSQVDTICECLLEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRREESLEKEPEYVPWTATSGPGGIRTVIIRQHEIVLKV-AYPQADSNLRNIVTEQLVALIDCFLDGYVSQLKSVDKSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYLWAASLAEKYCDFDILVQMCEQTD--NQSRLQRYMTQFADQ--NFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQA----HEHLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALASDFSEDMLQEKIEEMAEQERFLLHQETLPEQLLAEKQLNLSAMPVLT-----APQLIGLYICEENRRANEYDFKKALDLLEYIDEEE-----------DININDLKLEILCKALQRD---NWSSSDGKDDPIEVSKDSIFVKILQKLLKDGIQLSEYLPEVKDLLQA------------------------DQLGSLKSNPYFEFVLKANYEYYVQGQI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QNV4-1", "uniprot_id": "NU133_DANRE", "id": "F1QNV4-1", "name": "Nuclear pore complex protein Nup133", "aln": "MFSPRG---TPGSGRRQ----------APRTGGRRSV---SAVQPGLLFSP--RRSAVTARSTPTRVQS-HAVVESYNFDVQTFGSSLPVKVMEALTMADVDD-QISVKVEASGWAWMVCGERLIVWKVSQTSVA--------------KLSVCKDLQLPSSEFAYSADLVSISSSGP-LDLAPIQSISVLAVSPDGLVRFWPSLAHEGSYTEISLDLSG-HLSNYVAAVKGGSFIVSSYRGHLLRLSADSSG--KLHHRPVQQGQGMLSGIGRRVSSLFGIRGQPAD------LSVFSVLWVKASSCLYSLSSCGLSKWEVDENSETQVLSWSTNQIITDSITDAIWDSESN-YSEIKKGVNVLYLDMQPSNAGLVVLAAAWYPGDTPCVAYFCLVTLAESIVPSPDLLTVEVTKYNPPFQSEEELLKTRLVLPDPSSPAAYLYNEELVFACSTG--AGRGGLAEEKILFSSPGDRVRGGGVCADLPVFFSQNSGLVAVLARETASLLPETMEDSLCTSVAGPGPEGTPLETPPKIDMVAQE------------------DKTKLLKQAFLQFCRHDLVGAQSMVDELFP--SDGEGSAD------LDTVVTQIDLDLVDDYPACDPRWAESVPDEGAG----FTLTSLILLHQLEDKMKAHRCLMDFLLQTGLLDRLTSTKVRSCPMATR-LLLCEHAEKLSAAIVLKNHHAKHPELVNTAIQTALKKNSTDTPTNLTPADVFFREVSQISSIFECLLDEEEKALKEHP-DAARWGEVVLSVNDIIKDMLQAAAQYRETKASLYRAPENCSPEPEYIPWTASGGVGGVRSVISRQHELILRA-AYPHADAELRSVLCEQLVALLDSLLSGYVAQLTSLRRGGQQERYDTLENEYTQKRSELLKPLLELGQHQWVAALAEKYCDFDILVQLCERTD--NQSRLQQYMVKFADQ--NFADFLFRWYMEKGKRGKLLSQPMATHQQLASFLQA----HDHLSWLHDIHVQDYQRAHRTLYNQANMETRYFSKKKTLLALSKLTALASDMPEPVHRRQLNDIVEQERFLLHQETLPKQLLEEKQLNPDSMPLLS-----PQNLISLYICDENRGANEYDFKKALDLLEYFEEEN-----------GIDVDALKREIFSKALKKDWKESWSSSDDNDDPLEAARDSTFVKILQKLIQERVSLQTYLPDIKDLLQE------------------------DELESLKSKPYFEFLLRANYEHYLKVQI------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCW3-1", "uniprot_id": "NU133_DROME", "id": "Q9VCW3-1", "name": "Nuclear pore complex protein Nup133", "aln": "MERNLQKQLYGISRESSPGARRYSMPAASADSTRKSIFGGSASCAQMSGSLKRTALTNSRLSLSVRSTQSIAGIRSDYNSVESFGCPLPVVVNEALTFAGPGAGTVTAKVTQNGWAWVVQGRRLLIWQYKDTAKSGSPPRVGKLARRGGGLAQCRELTLPYSDLGHKSDLISVFQTEG------QQMASCIAVSATGEVRYWSSIAHDGNSVDLSILTGQEFVQLLSLPTQQGYLAVTTTCNLVFLRVGLTNGRYTLHHKTIKPATSFLGGFGKKFASILIGMNTGADKDQTLVGMCCESNLESGETIVAVLSDRAIQRWSLSNNGNTENLLYEDADMLRRIREEFITNFWKFRLPADSLEIDLHLLDFHVVKNKAYILAGAVNAAHAPQMCYALVTGTAQAERMLLESFTPLNMNKFFSAKTEEDCLSVRFVVG---SSHIYLYTSKVVYPLHLTNSVPTAELEAEKIEFHQHDDRILSAVICSQLPLFFSRTHGLVSITPGDFDGTEMMNMSSCNTPDLYAPNSCNASFAVADHSALTNSTNNLHLFELDPDEMYNELSDEVGQLKAAFLYHMKRNSNMVKTIVDELLRNVTAADPSGAPMDAYKLDRIVITIAEDLAEDIPIADPRWEEALADQEMNRHAIGSSRSMQIINQLRDKIIAFQHFITFLHSSLVWDKLNVIPCGSHSLKPTGCILADISEKIVAAMALRSIQTKLPKLIEEAIDATVALWHEEPQGSLTYQDIFYVKLSRFQNVFEALADIADDRIAAQNQTTISVAHFVNEINSIVLDVLGQVFKYRKQHASSFRLSHEKLPSYENLPWTAMAGSAGVRDTLTRLIDISVRYGSHCVSETELKQQLYQQIFELIDLVLDGRKTYLKSVR---DTEKFNVLQQQFEAQRRELISVLIKDRQYEYAAKIAEKYLDFQSLVLICDETQ--DKERLEDYTRKYEEY--DFSQFAINWHLRQNRHGEVFERFKGNQTALAQFMRD----HPSLGWIQLIFNGDFERAAKVLYELAQCETEFVARKKSMLSLAKLAAFAAAESD--LTAQVEKINADLTLVEYQSQLGHDVLESFGFDPAEQKVLK-----AEEIISLYIAEENETASETEFRKALELLSYVEQP----------------YDMRHKIWCAAIKRD---NWTDYD-PNNAVHYMQKLLFYKIIEISQLMGNDSENVLPPMEDFLES------------------------VELGDLPQQKPFQYLLKLTYEYVADMFKQPDDMEL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36161-1", "uniprot_id": "NU133_YEAST", "id": "P36161-1", "name": "Nucleoporin NUP133", "aln": "------------MSEKKVHLRLRKELSVPIAVVENESLAQLSYEEESQASLMDISMEQQQLRLHSHFDNSKVFTENNRYIVKTLQTDYSSGFSNDDELNGYID-------MQIGYGLVNDHKKVYIWNIHSTQKD-----------------------TPYITVPFRSDDNDEIAVAP-------RCILTFPATMDESPLALNPNDQDETGGLIIIKGSKAIYYEDINSINNLNFKLSEKFSHELELPINSSGGEKCDLMLNCEPAGIVLSTNMGRIFFITIRNSMGK--------------PQLKLGKLLNKPFKLGIWSKIFNTNSSVVSLRNGPILGKGTRLVYITTNKGIFQTWQLSATNSHPTKLIDVN---IYEAILESLQDLYPFAHGTLKIWDSHPLQDESSQLFLSSIYDSSCNETYYILSTIIFDSSSNSFTIFSTYRLNTFMES-----ITDTKFKPKIFIPQMENANDTNEVTSILVMFPNAVVITQVNSKLDSSYSMRRKWEDIVSLRNDIDIIGSGYDSKSLYVLTKQMG-----------------VLQFFVKENEETNSKPEVGFVKSHVDQAVYFSKINANPIDFN----LPPEISLDQESIEHDLKLTSEEIFHSNGKYIPP-------MLNTLGQHLSVRKEFFQNFLTFVAKNFNYKISPELKLD----------LIEKFEILNCCIKFN-SIIRQSDVLNDIWEKTLSNYNLTQNEHLTTKTVVINSPDVFPVIFKQFLNHVVFVLFPSQ-----NQNFKLNVTNLINLCFYDGILEEGEKTIRYELLELDPMEVDTSKLPWFINFDYLNCINQCFFDFTFACEEEGSLDSYKEGLLKIVKILYYQFNQFKIWINTQPVKSVNANDNFININNLYDDNHLDWNHVLCKVNLKEQCIQIAEFYKDLSGLVQTLQTLDQNDSTTVSLYETFFNEFPKEFSFTLFEYLIKHKKLNDLIFRFPQQHDVLIQFFQESAPKYGHVAWIQQILDGSYADAMNTLKNITVDDS----KKGESLSECELHLNVAKLSSLLVEKDNLDINTLRKIQYNLDTIDAEKNISNKLKKGEVQICKRFKNGSIREVFNILVEELKSTTVVNLSDLVELYSMLDDEESLFIPLRLLSVDGNLLNFEVKKFLNALVWRRIVLLNASNEGDKLLQHIVKRVFDEELPKNNDFPLPSVDLLCDKSLLTPEYISETYGRFPIDQNAIREEIYEEISQVETLNSDNSLEIKLHSTIGSVAKEKNYTINYETNTVEY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. : * : .. *. : . . : : *:. : .:: :*: : * . :* : : .: . : . : . . : : :: . . .* . . .:: . . :: . .. . : *. . :. : . . : . . : : . . .* : : . . : : * : . : ::*.. :. : . . . . . :* : : .: .*: . . * : .: .* . . .: . : ::* : . :: *: . * : * : ..: :. : ..::: :: ** :. . . . : : : : : .. .:. :: : . : : . . : . . :. : . :: . : . : .: :.: :: : :: : * :** * *:. ** : : :. :. * : : :*: :.: :.: : ..:: : : * .*:: : :.*:: * . * .* : :: :* *. .:* .: .. . : : . : : . :. : . . . : : :* . :. :: . ::* . .:: :. : *: . : :. :. . * : : * : :: * .. :: *: . . ", "identical_positions": 46, "similar_positions": 279, "identity": "3.61%" }, { "cls_id": "homologset.agr.SGD:S000001792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZS7-1", "uniprot_id": "HBS1L_MOUSE", "id": "Q69ZS7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DNP----EEEYGYEDLRESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQPWKEKSERAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSEENGLSVRAPHKGPPGDDVSVASPNIPETGTPKSALPPPSLQTSEELGSTPTPVRKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVNLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM7-1", "uniprot_id": "HBS1L_RAT", "id": "Q6AXM7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DNP----EEEYGYEDLKESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQTLKEKSERAVCAGQPSK---VISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLPSEENGHNVRAPYKGPPGDDVSIASPNVPETGTPKSTAHPPSLQTSEELGCTPTPLRKSGKLRQQIDVKAGLEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTSRSQSSDLTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYVQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILIFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y450-1", "uniprot_id": "HBS1L_HUMAN", "id": "Q9Y450-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDA-IASSDVLETAS-KSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVP-IKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRP---IALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W074-1", "uniprot_id": "HBS1_DROME", "id": "Q9W074-1", "name": "Protein HBS1", "aln": "MSRHRIVRTMDYNDEYDGYDDIYGHSVEDEHCISPTDAQQWLYDRARGQQSISAFISKNKDIQEEEADEDEDEDAAFAKARRDSESFQMPQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEILNEETNKSAKP----------------AVNKMKAPAAPVLPKTVSKTVP--------------TPPPKISLKEPRRG-----FEIPSPKVPSSPVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLDTVGWSQDRFTEIVTKLKSFLKLAGFKDSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIE--NFKIPERA----IDRPLRMSVSDIYKGTGSG---FCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFP--------QTCVFAGDQVSVTLPALDINNVTVGCIISDPQTP-IPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRP---ICIERYADFKELGRVMLRVAGVTIAAGMVTKIR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32769-1", "uniprot_id": "HBS1_YEAST", "id": "P32769-1", "name": "Elongation factor 1 alpha-like protein", "aln": "------MAYSDYSDGADDMPDFHDEGEFDDYLN--------------------------------------DDEYDLMNEVFPTLKAQLQDYQGWDNLSLK--------------------LALFDNNFDLESTLAELKKTLKKKKTPKK----------------PIAAANGSANVTQKLANISIS-----------------------------------QQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGN-TASKKKIRHLGSKQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.: : *::... *:: :: . : . : . :: * : :. .:*::. * : : : : : * .. ::. .. . . . : . ... . . . . : ::*:************::** . :.: ::* ::**:. ** ** :**::*:*.*** **:*:.: :::.* .*::*****:**:** * * :***:*:* **.: . **:**: .***:** :*. ***: :* :.:**:* *.*.*:** ** ** :* ** :.:: : * **::**.: : **.* *:. :: ** .:. * *: :.* :: . :. ::*::*:* : .: : ...: . .. : : . . ** *.:.* .: * : .. . . * * .: *::: *: * *.:*. :** : :* : :.*.. . *** : * . . *:**:: . : : : ..***.:** * *:*** :::* ", "identical_positions": 139, "similar_positions": 201, "identity": "19.12%" }, { "cls_id": "homologset.agr.SGD:S000001794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A321-1", "uniprot_id": "D4A321_RAT", "id": "D4A321-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "aln": "MEDAGEDASIHRLEGTNLDSQVGGLICKTKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKD------DGEDKKKSRISSYKDWEESKDDQKDAEEDGDEQAGRSSRRDRHYRSARVETPSHPGGVSEEFWERSRQRE-RDRREHGVYASSKEDKDRKKEKSRDRDHDRKRDRADERDRSRHSSRS-------ERDGGSERSSRRNEPESPRHRPKDAATP-------SRSTWEEEDSGYGSSRRSQWETPSPTPSYRDSERSHRPSTRDRDRSVRSKSSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREDGEEGIAFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERRKAQHKHWELAGTKLGDIMGVKKEEEPD--KAMTEDGKVDYRTEQKFADHMKEK-SEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHQDGYT-DYG-MIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCT-SENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDADKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLS--GAPGDILIFMPGQEDIEVTSDQIVEHLEELEN----------APALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLL-QFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVK---------QAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKIYTPGRKEQGEPMTPRRTPARFGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92620-1", "uniprot_id": "PRP16_HUMAN", "id": "Q92620-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "aln": "MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKD------DGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRE-RERREHGVYASSKEEKDWKKEKSRDRDYDRKRDR-DERDRSRHSSRS-------ERDGGSERSSRRNEPESPRHRPKDAATP-------SRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKEEEPD--KAVTEDGKVDYRTEQKFADHMKRK-SEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYT-DYG-MIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCT-SENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLS--GAPGDILIFMPGQEDIEVTSDQIVEHLEELEN----------APALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLL-QFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVK---------QAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKIYTPGRKEQGEPMTPRRTPARFGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY54-1", "uniprot_id": "Q9VY54_DROME", "id": "Q9VY54-1", "name": "RNA helicase", "aln": "MSDD-DESGVHRLEGTAGQETRGGLVIRKPKDAGAGGGGGFKVPQGSMLGLDKLAAKRRAEKERSERLISFKDSEFDDTGGGSSTPQANASGASSEFAFKKPDTKSFEKLRG--QLREHKDDTPSHTGGVSEKARERLREHIQRDRKRGPVSSTAAEGRDRDRDWDRDRRRDRDRDRDRDRDRRQHRERERDRHRSWDRDRGRDRDRDRSMSERSVHTPREPGTPGGSSGGISNSSWDDEDGEFGQ-RKSDWDMPTPR---RHGNKSGDWSVRSGGSRRNHGRQDDTVRPTPAHRYNQWAHGRKRSGATP----------WGED------PESLDLWEEEQRRLDREWYNIDEGYDDENNPFGGPNSEYFRKREEQLEQKRTKRISAQQRQNNRDNELWERNRMLTSGVVTLISVNDDFDEEALERVHLLVHHIIPPFLDGRIVFTKQPEPVVPVKDPTSDMALLARKGSALVRNYREQKERRKAQKKHWELSGTKLGNIMGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYS-KRG-MIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCT-SERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHLT--PNEGDMLIFMPGQEDIEVTCEVLEERLAEIDN----------APALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLL-QFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVK---------ESGRSGREKKKQAAEHLKEMEEQMLKAQHEMEERKQQAAEREEQ-LATKQEIATPGN------ATPRRTPARIGL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15938-1", "uniprot_id": "PRP16_YEAST", "id": "P15938-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "aln": "-------------MGHSGREERIKDIFKELTSK--------ELTPGLLLTLQKLAQK--------------------------PNTNLEQFIASCKALTKLSSNNPIIFNELLELLKNKSEEDSTGPKKIAPSINKRKKFKIQLDLDDN----EDELDSPVQKKPAPTRTLFKRIDKLKAKQLRQYSPTVK------DPSPNSEQQTQNGHAETKDYEP-------------TRSEVVEED--------------------------------------------------------------------------------------------------------REWYDNDDDYGN-------------LVPEPLSELPEEAKLLPVIRNIDNDDALRNTVQLYPIPLKQRMEWIPPFLSKFALENKVPTSIIIGSISETSSQVSALS-MVNPFRNPDSEFSANAKRGSKLVALRRINMEHIQQSRDNTTVLNTAMGEVLGLEN------------NNKAKDKSNQKICD-------DTALFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKSIVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTLDKYSCVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSATMNAKKFSAFFGNAPQFTIPGRTFPVQTIYTSNPVQDYVEAAVSQAVKIHLANDCSSGDILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEINDIEILPIYSALPADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISKANADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDELSKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAVRNGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANNFSSHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCICSGFAHQAAKITGLRNYVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDPFWLMEYGGLLYDIKRIKNDQEATTTGLFGEHYEHTLDKVEDDIDINIRRCKDMRDSVIQELKMTDNSNKEDKKQKTKKQNILNGKENSMKPFKRRKPFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : . . :* *: ** . : : . : : . :. . :. : .: . :: . :* : : : .:. * : *: :: :: : . . ::. .. .* : * :.* :** *:** *:.*.: * . . :: . *: :.*: : :: . : :. * .. . :: . :: .: : .: . * *.::. *::: *::** * * : *: : .:.: : .* :*:::*::. ..*.. :.:**:.* . *. * . :. **:* :.:**.:**:*.:::::***********:***:::**: . * * ********:******: ** **::***:***** * ** * :*::********:* : ** **.:*:********.**:*:*::: ::*** *****:*****::.**::****.* * ********: :::... :****:**.*::::**: **:****.******.* : : *:: :: . : :***** **:*** ****. . ** ::**********:.** :***.**.****:**:**:*:* * ***:***:*********.** .:****: :*::: *:********:*.:******.* * * :* *:* ** :.:*.*:*:**::**:* :* **. * *.:***:*. .::*::: *** *:* ******** :***** *:.*:* *:** .:***** ***: **: **:*: ***.**:: *:: :.*::* ** *: .*.:.: *.* ****::****:.: :***::.*: :**:::**:. :*****:*.*:* * *:*****:**:***: *.*:** ** * * :::.:* :* .. .: : . :: :: .:. *: . . : . . : : * : ", "identical_positions": 382, "similar_positions": 333, "identity": "29.89%" }, { "cls_id": "homologset.agr.SGD:S000001795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS74-1", "uniprot_id": "OMA1_RAT", "id": "D3ZS74-1", "name": "Metalloendopeptidase OMA1, mitochondrial", "aln": "MNFLYGLQSATRNQFLSGVNTLARRRTWTPPAG----CPLASRLPAVNANWGLSTVSHCYSVILLPRNLHFCRTLKNKRSRCLSSAQSKEMGVLTYNWTVWGD-----------------ASCSPNYAA-IREVRSFHTSAPRQAAP-VPLLMLILKPVQKLLAIIVGRGIRKWWQALPPDKKALFKDSVKRNKWRLLLGLSAFGLLFVVFYFTHLEVSPVTGRSKLLLVGKEHFRLLSDLEYEVWMEEFKNDLLPEEDPRYLTVKKVVYHLTQCNQDVPGVS-----EINWVVHVVHSPKVN--AFVLPNGQVFVFTGLLNSVTDMHQLSFLLGHEIAHAVLGHAAEKASLVHLLDFLGMIFLTMIWAICPRDSLAVLGQWIQSKLQEYMFDRPYSRTLEAEADKIGLQLAAKACVDVRASSVFWQQMEFSESLHGYPKLP--EWLSTHPSHGNRAEYLDRLIPQALKLREVCNCPPLSGPDPRLLFRLTVKHLLEDSEKEDLNITVKKQKPDALPIQKQEQIPLTYALGKRTAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8H7-1", "uniprot_id": "OMA1_MOUSE", "id": "Q9D8H7-1", "name": "Metalloendopeptidase OMA1, mitochondrial", "aln": "MSLLYGLQSTRINRFLSGVNNLANRRQWTPPAS----CPLAPKLRAVNAYWGLNTVSHCHSVTLLPRNFLFCRTLNHKKSRCLSSAQSKELGVLTYRCTVRGDSVLRQGARKVAGVPALAASCSPSCPA-VIEARSFRTSARVQAAP-VPLLLLILKPVQKLLAIIVGRGIRKWWQALPPNKKELFKDSVRKNKWRLLLGLSAFGLLFVVFYFTHLEVSPVTGRSKLLLVGKEHFRLLSDLEYEVWMEEFKNDLLPERDPRYLTVKEMVYHLTQCNRDVPGIS-----ETNWVVHVVDSPAVN--AFVLPNGQVFIFTGLLNSVTDVHQLSFLLGHEIAHAVLGHAAEKASLVHLLDFLGMIFLTMIWAICPRDSLAVLGQWIQSKLQEYMFDRPYSRTLEAEADKVGLQLAAKACADVRASSVFWQQMEFSESLHGYPKLP--EWLSTHPSHGNRAEYLDRLIPQALKLREVCNCPPLSGPDPRLLFRLTVKRFLEDSEKEDLNITVKKQKTDALPMQKQEQIPLTYVLEKRTAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E52-1", "uniprot_id": "OMA1_HUMAN", "id": "Q96E52-1", "name": "Metalloendopeptidase OMA1, mitochondrial", "aln": "MSFICGLQSAARNHVFFRFNSLSNWRKCNTLASTSRGCHQVQVNHIVNKYQGLG-VNQCDRWSFLPGNFHFYSTFNNKRTGGLSSTKSKEIWRITSKCTVWNDAFSRQLLIKEVTAVPSLSVLHPLSPASIRAIRNFHTSPRFQAAP-VPLLLMILKPVQKLFAIIVGRGIRKWWQALPPNKKEVVKENIRKNKWKLFLGLSSFGLLFVVFYFTHLEVSPITGRSKLLLLGKEQFRLLSELEYEAWMEEFKNDMLTEKDARYLAVKEVLCHLIECNKDVPGIS-----QINWVIHVVDSPIIN--AFVLPNGQMFVFTGFLNSVTDIHQLSFLLGHEIAHAVLGHAAEKAGMVHLLDFLGMIFLTMIWAICPRDSLALLCQWIQSKLQEYMFNRPYSRKLEAEADKIGLLLAAKACADIRASSVFWQQMEFVDSLHGQPKMP--EWLSTHPSHGNRVEYLDRLIPQALKIREMCNCPPLSNPDPRLLFKLSTKHFLEESEKEDLNIT-KKQKMDTLPIQKQEQIPLTYIVEKRTGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBI7-1", "uniprot_id": "OMA1_DANRE", "id": "E9QBI7-1", "name": "Metalloendopeptidase OMA1, mitochondrial", "aln": "-----MQQTCIRLVKLDMLSTLTRFRTHS--------AIRCCAQRLFHCRPSLFISARTYFIKIDSSSLPKLKGSVSFSASCVSLGSSR-LGLCSSSFKTGAP-------------------AALRAPVVFQRTRGFHTSGRRRALPALPLLWMVLKPLQKIMAIILGRSIRKWWVALPANKKQLFREWSWRRRWHFLGAGTGLLFIASLFFFTHLDESPITGRTRLLVFSRKNFRELAQFNADAFMEEFKDSLIASSDPRHKVVEQVVQILAQRNQDIAEIS-----AVPWTVHVVDSPTMN--AFVLPNGEIFVFTGMLNAVTDIHQLTFILGHEMAHALIGHAAEQASLSHVVELLSLVLLTAIWAVCPRDSLAALGHWIQGKLVQFLFDRPFSRKLEAEADQVGLQMAAKACADVRAGPVFWEQMEIFDQLSGQPTMP--EWLSTHPSHQNRVRQLDRLIPEALELRARCNCPELPKTDPRVVFNEAVRLVLEGKKEQMLEKEEKNGKT-----QTGDMFP-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36163-1", "uniprot_id": "OMA1_YEAST", "id": "P36163-1", "name": "Mitochondrial metalloendopeptidase OMA1", "aln": "----------------------------------------------------------------MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGP-----------------------------SYRRFNNGEYSQKSS--------------FKSILLDKSSRKYLALLFGG--------------------------CSLFYYTHLDKAPVSDRSRFIWVSRPLELTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWEIHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLSKAPIYSLLGLVLYTVTGAHA-----------INNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSSMGN-YYKSFFSM----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . * : * *... : . : :*::.:. **: * . :*::***: :*::.*:::: ..: :.: . .: ::.::. .. ::::. : : . . :. * :***..* . *****.*::*:*:.:* :: . :: :*.**:** : *:**: . : .:*.::: * * . *:. * : :: * ** :*:*** :** : ::** : : . .*::* :. . : *:*****: .* . :.: :*:* :: .:*. : : .* ", "identical_positions": 64, "similar_positions": 128, "identity": "11.94%" }, { "cls_id": "homologset.agr.SGD:S000001796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AB80-1", "uniprot_id": "A0A8I6AB80_RAT", "id": "A0A8I6AB80-1", "name": "", "aln": "MRNPGGSLLHTLPRALQHAGRPGGAEQPGRWAPERTAGGDCSEDRLPRGGGAS--AAAAAAAASGALLGAYLERHGPPAASDLPAPAGALAGGPGSGGG-VVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLQHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGF-VLGMGLMVVGVLIGTFIAHVVCKRLLTAWVAARIQSSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQN-AVFSITDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQS--VSGYFVFCLQIVISIGLMFYVVHRAQVELNAAIVACEMELKTSLVKGSQPNPSGSSFYNKRTLTFSGARSIRLRESHTTVHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U145-1", "uniprot_id": "TMM64_MOUSE", "id": "Q3U145-1", "name": "Transmembrane protein 64", "aln": "MRNPGGSLPHTLPRALQHAGRTGVVEQPGRWAPERTAGGDRSEDRLPRGGGASAAAAAAAAAASGALLGAYLERHGLPAASDLPAPAGALAGGPGSGGG-VVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLQHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGF-VLGMGLMVVGVLIGTFIAHVVCKRLLTAWVAARIQNSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQN-AVFSITDVPLPSYLMASSAGLLPTQLLNSYLGTTLRTMEDVIAEQS--LSGYFVFCLQIVISIGLMFYVVHRAQVELNAAIVACEMELKTSLVKGNQSDPSGSSFYNKRTLTFSGG-GINIV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YI46-1", "uniprot_id": "TMM64_HUMAN", "id": "Q6YI46-1", "name": "Transmembrane protein 64", "aln": "MRSPGGILLQALPRLLQHAALPGLAELPARWALPRGAGGDGPADRLPRGGGAS--AAAAAAAASGALLGAYLERHGPPEASELPEPGGALAGGPGSGGGGVVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALV----RRYLHHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGF-VLGMGLMMVGVLIGTFIAHVVCKRLLTAWVAARIQSSEKLSAVIRVVEGGSGLKVVALARLTPIPFGLQN-AVFSITDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQS--VSGYFVFCLQIIISIGLMFYVVHRAQVELNAAIVACEMELKSSLVKGNQPNTSGSSFYNKRTLTFSGG-GINVV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNR8-1", "uniprot_id": "Q9VNR8_DROME", "id": "Q9VNR8-1", "name": "VTT domain-containing protein", "aln": "-MSCNNNNNYKNKTTYGYSNNNDTNCIMQKPVPASTAPAFPQLIQASCSNAVEVDPPDSIVGAAGNSE-ALFAAQRTPDTSEDSECDPFLASRRATRSSATTSVLHNRKRNSCWGRAHSFLTRNWYLGCLVPATILGALVFIGWATRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGC-LRGWVTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDTGRAILRVISGPKAFRVVLFTRLTPIPFGVQN-VIFGISSINTRDYHVATLIGLLPAQTINVYLGSTLRSMHEVLSDNDTKLTGYISFLFEVICGVALMFWVLQKARKELSETLLSADYNNE-----GKHPDVQV----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36164-1", "uniprot_id": "TVP38_YEAST", "id": "P36164-1", "name": "Golgi apparatus membrane protein TVP38", "aln": "-----------MSQSYEAGNAN------------MGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTNAGLSFNDEVNVNDDDFLDIYNMSPRERLMHN-----IRKNVQKLQFYFYSLRLWQQIIIVLLGIMLMIMGILLLVFHN-AILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLSTTTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIAN-IITTPKLFIYLFIGSRVKSLAESESTGS--RVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVS----TDQLPELSFEV--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . * : . .: . . : :. . : : : :. * :: : :: : : : : : .*:** ** :* ::* ::* . * : :* * :... : : . *: ::. .. :: : ** *:*:.: * .: .: .: .: :*. * : ::*: :::: : : . : : : :.* ::: : : : : . .. .: . ", "identical_positions": 23, "similar_positions": 98, "identity": "5.76%" }, { "cls_id": "homologset.agr.SGD:S000001798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35652-1", "uniprot_id": "LHX8_MOUSE", "id": "O35652-1", "name": "LIM/homeobox protein Lhx8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYWKSDQMFVCKLEGKEVPELAVPREKCPGLMSEECGRPAALAAGRTR--------------------KGAGEEGLVNPEGAGDEDSCSSSAPLS---PSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLK------------------VNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTR------CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHFDCMLDNLKREVENGNG----ISVEGALLTEQDVNHPKPAKRARTSFTADQ---LQVMQAQFAQDNNPD----------------AQTLQKLAERTGLSRRVIQV---WFQNCRARHK----------KHVSPNHSSSAPVTAVPSSRLSP---------------------PMLEEMAYSAYVPQDGTMLT-ALHSYMDAH------------------------------QQLLD-SSPCYPIQ------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6V6-1", "uniprot_id": "G3V6V6_RAT", "id": "G3V6V6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYWKSDQMFVCKLEGKDVPELAVPREKCPGLMSEECGRPAALAAGRTR--------------------KGAGEEGLVNPEGAGDEDSCSSSAPLS---PSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLK------------------VNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTR------CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHFDCMLDNLKREVENGNG----ISVEGALLTEQDVNHPKPAKRARTSFTADQ---LQVMQAQFAQDNNPD----------------AQTLQKLAERTGLSRRVIQV---WFQNCRARHK----------KHVSPNHSSSAPVTAVPSSRLSP---------------------PMLEEMAYSAYVPQDGTMLT-ALHSYMDAH------------------------------QQLLD-SSPCYPIQ------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68G74-1", "uniprot_id": "LHX8_HUMAN", "id": "Q68G74-1", "name": "LIM/homeobox protein Lhx8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQILS---------------------RCQGLMSEECGRTTALAAGRTR--------------------KGAGEEGLVSPEGAGDEDSCSSSAPLS---PSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLK------------------VNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTR------CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDCMLDNLKREVENGNG----ISVEGALLTEQDVNHPKPAKRARTSFTADQ---LQVMQAQFAQDNNPD----------------AQTLQKLAERTGLSRRVIQV---WFQNCRARHK----------KHVSPNHSSSTPVTAVPPSRLSP---------------------PMLEEMAYSAYVPQDGTMLT-ALHSYMDAHSPTTLGL-----------------------QPLLPHSMTQLPISHT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q969G2-1", "uniprot_id": "LHX4_HUMAN", "id": "Q969G2-1", "name": "LIM/homeobox protein Lhx4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQSATVPAEGAVKGLPEMLGVPMQ---QIP----------------QCAGCNQHILDKFILK------------------VLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGTK------CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL----KKDAGRHRWGQFYKSVKRSRGSSKQEKES---SAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLN-GLDYTVDSNLGIIAHAGQGVSQTLRAMA-------GGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5YCK6-1", "uniprot_id": "A0A8I5YCK6_RAT", "id": "A0A8I5YCK6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAHSLRSAWATFLVPDALLEELECCTLQDSEDYSNPVSCCLDQQP--------------------TQESKLPQTPKTLSTQGNTSPLKVQLVYTTNIQEPNVYSEVQEPKQSVLPPKTSAAAQLDELMAH------------------LNELQAKVSVKADASRKPLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEELGS--SPFFERNGLAYCSKDYHHLFSPRCAYCAAPITDKVLTAMNKTWHPEHFFCSHCGEVFGAEGFHEKD--KKPYCRKDFLAMFSPK---------------CGGCNRPVLEN--YLSAMNTV---WHPECFVCGD----------CFSSFSSGSFFELDGRPFCELHY--------------------HHRRGTLCHDCGQPITGRCIS-AMGHKFHPEHFVCAFC----------------------LTQLPKGIFKEQNNKTYCEKCFIKLFSQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36166-1", "uniprot_id": "PXL1_YEAST", "id": "P36166-1", "name": "Paxillin-like protein 1", "aln": "MYNSIYGSPFPKINPKVRYKTALERAGFDTKPRNPFSSQRNASTGSLQASVKSPPITRQRNVSAAPSVPVTMKSAYTASSKSAYSSVKGESDIYPPPVLENSERRSVTPPKNSNFTSSRPSDISRSISRPSERASQEDPFRFERDLDRQAEQYAASRHTCKSPANKEFQAADNFPFNFEQEDAGNTEREQDLSPIERSFMMLTQNDTASVVNSMNQTDNRGVLDQKLGKEQQKEESSIEYESEGQQEDENDIESLNFEPDPKLQMNLENEPLQDDFPEAKQEEKNTEPKIPEINVTRESNTPSLTMNALDSKIYPDDNFSGLESSKEQKSPGVSSSSTKVEDLSLDGLNEKRLSITSSENVETPYTATNLQVEQLIAQLDDVSLSRNAKLDMNGNCLNAVDRKASRFKKSSAYLSGYPSMDIPVTQQTSIVQNSNTNLSRQTILVDKGDVDEDAPSESTTNGGTPIFYKFKQSNVEYSNNEGMGSQETFRTKLPTIEALQLQHKRNITDLREEIDNSKSNDSHVLPNGGTTRYSSDADYKETEPIEFKYPPGEGPCRACGLEVTGKRMFSKKENELSGQWHRECFKCIECG---------IKFNKHVPCYILGDEPYCQKHY--------------------HEENHSICKVCSNFIEGECLENDKVERFHVDCLNCFLCKTAITNDYYIFNGEIPLCGNHDMEALLKEGIDNATSSNDKNNTLSKRRTRLINFN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::. . : . : . : : : . : . : : . . . : . : . : :* . . : . . . . . : .. . : ", "identical_positions": 1, "similar_positions": 40, "identity": "0.14%" }, { "cls_id": "homologset.agr.SGD:S000001800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q5C9-1", "uniprot_id": "NOLC1_MOUSE", "id": "E9Q5C9-1", "name": "Nucleolar and coiled-body phosphoprotein 1", "aln": "MADTGLRRVVPSDLYPLVLRFLRDSQLSEVASKFAKATGATQQDANASSLLDIYSFWLNRSTKAPKVKLQSNGPVTKKAKKETSSSDSSEDSSEDEDKKAQGLPTQKAAAQVKRASVPQHAGKAAAKASESSSSEESSEEEEE-DKKKKPVQQKAAKPQAKAVRPPAKKAESSESDSDSDSDSSSEEETPQTQKPKAAVAA-----KAQTKAEAKPGTPAKAQPKVANGKAAASSSSSSSS--DDSEEEKKAAAPPKKTVPKKQVVAKAPVKVAAAPTQKSSSSEDSSSEEEEGQRQPMKKKAGPYSSVPPPSVPLPKKSPGTQAPKKAAAQTQPADSSDDSSDDSDSSSEEEKKPPAKTVVSKTPAKAAPVKKKAESSSDSSDSDSSED-EAPAKPVSTTKSP--KPAVTPKPSAAKAVTTPKQPAGSNQKPQSRKADSSSSEEESSSSEEEEASKKSATTPKAKVTAKAAP---AKQAPQAAGDSSSDSDSSSSEEEEKTP-KPPAKKK----AAGGAVSTPAPGKKAEAKSSSSSSSSSSEDSSEEEKKKKPKATTPKIQASKANGTPAS--LNGKAAKESEEEEEEEETEEKKKAAGTKPGSGKKRKQNETADEATTP--QAKKVKLETPNTFPKRKK------GERRASSPFRRVREEEIEVDSRVADNSFDAKRG------------------------------AAGDWGERANQVLKFTKGKSFRHEKTKKK-------------------------------------------RGSYRGGSISVQVNSVKFDSE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41777-1", "uniprot_id": "NOLC1_RAT", "id": "P41777-1", "name": "Nucleolar and coiled-body phosphoprotein 1", "aln": "MADTGLRRVVPSDLYPLVLGFLRDNQLSEVASKFAKATGATQQDANASSLLDIYSFWL-KSTKAPKVKLQSNGPVAKKAKKETSSSDSSEDSSEEEDK-AQ-VPTQKAAAPAKRASLPQHAGKAAAKASESSSSEESSEEEEEEDKKKKPVQQKAVKPQAKAVRPPPKKAESSESES----DSSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSED-EAPAKPVSATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEE-ATKKSVTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKK----AAGAAVPKPTPVKKAAAESSSSSSS--SEDSSEEEKKKPKSKATPKPQAGKANGVPAS--QNGKAGKESEEEEE--DTEQNKKAAGTKPGSGKKRKHNETADEAATP--QSKKVKLQTPNTFPKRKK------GEKRASSPFRRVREEEIEVDSRVADNSFDAKRG------------------------------AAGDWGERANQVLKFTKGKSFRHEKTKKK-------------------------------------------RGSYRGGSISVQVNSVKFDSE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14978-1", "uniprot_id": "NOLC1_HUMAN", "id": "Q14978-1", "name": "Nucleolar and coiled-body phosphoprotein 1", "aln": "MADAGIRRVVPSDLYPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWL-KSAKVPERKLQANGPVAKKAKKKASSSDS-EDSSEEEEE-VQGPPAKKAAVPAKRVGLPP--GKAAAKASESSSSEESSDDDDEEDQKKQPVQ-KGVKPQAKAAKAPPKKAKSSDSDS----DSSSEDEPPKNQKPKITPVT----VKAQTKAPPK---PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE-KTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS---DDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEE---EKKKAAVVVSKSGSLKKRKQNEAAKEAETP--QAKKIKLQTPNTFPKRKK------GEKRASSPFRRVREEEIEVDSRVADNSFDAKRG------------------------------AAGDWGERANQVLKFTKGKSFRHEKTKKK-------------------------------------------RGSYRGGSISVQVNSIKFDSE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32583-1", "uniprot_id": "SRP40_YEAST", "id": "P32583-1", "name": "Suppressor protein SRP40", "aln": "-----------------------------------------------------------MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSS--------------------------SSSSSSSSSSGESSS-----------------SSSSSSSSSSSDSSDSSDSES--------------------------------------------------SSSSSSSSSSSSSSSDSESSSESDSSS-------------------SGSSSSSSSSSDESSSESESEDETKKRARES--------------DNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSD--------------------------------------SSSDSDSSSSDSSSDSDSSSSSSSS------------------------------SSDSDSDSDSSSDSDS----------------SGSSDSSSSSDSSSDESTSSDSSDS---DSDSDSGSSSELETKEATADESKAEETPAS---------------------------------------SNESTPSASS--SSSANKLNIPAGTDEIKE------GQRKHFSRVDRSK-----INFEAWELTDNTYKG------------------------------AAGTWGEKANEKLGRVRGKDFTKNKNKMK-------------------------------------------RGSYRGGSITLESGSYKFQD-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PFZ1-1", "uniprot_id": "M9PFZ1_DROME", "id": "M9PFZ1-1", "name": "", "aln": "------MTDLLKIADAIVLEYLQSKDK-NLAKVFQQKTKAASVAKSSPKLSEILQFYQTKSPKKIPAIKATAGDSSEDSDSD-SESDAAPKKPATAPALTNGKAVKKAASSTSEDSDSEEEKKPAAKATPAKAVGKKAKSSSEDSSSEEEAPKKAAPVKAPPAKAAPAKKVESSSED------SSSEEEPAKPAVKATTTKVAPAKKADSSSEESSSDEETKPAAKPVAKAAPAKKAASSSEESDSDDEPAAKKPAVQP------------AAKPAPKAAASSSEDSSSEEEVKPAAKSAAKLAPAKKGASSSDDSSSEDEAPKKAATLAKPISKAAPTKKADSSTEDSSSEDDAPKKVAPAKATPAKAIPAKKAASSDDSSSEEEAPKK-AAPANATPARAPPAKKAASSDDSSSEEEAPKKAAPAKATPAKATPAKKAASSDDSSSEEEAP------------KKAAAPAKATPAKKAKSSSEDSDSDEEEAPKKPAAKAVAKAASSED----SDSSEDEKPAKAAPKALAKSAKAASSDSDDSSDEETPAVKPAVKKTAAPAKKADSSSDESDSGEESGEVKPNSATNGNEKTAQKRKFSGGDQDEATPNKKYNNFVKSGEQQKNDFTSTPNNTFSRNHNMNNSGGGSGRRSPFRRVRTEDVVVDSRVQDMSFEAKENDFKKHNNGRGGRGGSGFSGRPDRSTWETNKFNGEGGGDGGGFKKIGDRKSFGGFDNNQRGGRGGGGRGGGGGFGGRGGGGRGGGGGFGGRGGGGRGGGGFGGRGGRGGGGRGGGFGNKSFDSSAPKQNKKITFDN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* . :. .. *.*.: ... ::.:: :.: :.:. .: . ... . .*.*:. ..:..:..::*** .:...* : :.. :***::***:.* : . .. .: . . . .: .:.. :..**..:. . : . :.:.. :. :.*...**...:... . : .::*..:.**... . **.**.:.:... : .. ..: .* .: * :..*:. * .: .: .. . . . * . :. * * . * : :: .. : : :: .. * * .. *.* ..: : **. **. .. .*:. ", "identical_positions": 45, "similar_positions": 177, "identity": "5.51%" }, { "cls_id": "homologset.agr.SGD:S000001801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIP7-1", "uniprot_id": "S15A1_MOUSE", "id": "Q9JIP7-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSRGCFGYPLSIFFIVVNEFCERFSYYGMRALLVLYFR--------NFLGWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHN--------------------GSPDSLPVHVALSMVGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINGGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKK-FQPQGNIMGKVAKCIGFAIKNR--------------FRHRSKAYPKREHWLDWAKEKYDERLISQIKMVTKVMFLYIPLPMFWALFDQQGSRWTLQATTMNGKIG-----------------AIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCG-FNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKT-LPVFPGG-NQVQIKVLNIGNNNMTVHFPGNS---VTLAQMS--------------------------QTDTFMTFDID-KLTSINISSSGSPGVTTVAHDFEQGHRHTLLVWNPSQYR----VVKDGLNQKPEKGENGIRFVNTLNEMVTIKMSGKVYENV-TSHNASGYQFFPSGEKQYTINTTAVAPTCLTDFKSSNLDFGSAYTYVIR-RASDG---CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVG-----NIIVLIVAGAGHFPKQWAEYILFASLLLVVCVIFAIMARFYTYINPAEIEAQFDE----DEKKKG---------IGKENPYSSLEPV---------SQTNM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51574-1", "uniprot_id": "S15A1_RAT", "id": "P51574-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSRGCFGYPLSIFFIVVNEFCERFSYYGMRALLVLYFR--------NFLGWDDDLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHD--------------------GSPNNLPLHVALSMIGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINAGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKK-FQPQGNIMGKVAKCIRFAIKNR--------------FRHRSKAFPKRNHWLDWAKEKYDERLISQIKIMTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIG-----------------TIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCG-FNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKT-LPVFPSG-NQVQIKVLNIGNNDMAVYFPGKN---VTVAQMS--------------------------QTDTFMTFDVD-QLTSINVSSPGSPGVTTVAHEFEPGHRHTLLVWGPNLYR----VVKDGLNQKPEKGENGIRFVSTLNEMITIKMSGKVYENV-TSHSASNYQFFPSGQKDYTINTTEIAPNCSSDFKSSNLDFGSAYTYVIRSRASDG---CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIG-----NIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIEAQFDE----DEKKKG---------VGKENPYSSLEPV---------SQTNM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46059-1", "uniprot_id": "S15A1_HUMAN", "id": "P46059-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFT--------NFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHD--------------------GTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKK-FKPQGNIMGKVAKCIGFAIKNR--------------FRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIG-----------------ALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCG-FNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKT-LPVFPKG-NEVQIKVLNIGNNTMNISLPGEM---VTLGPMS--------------------------QTNAFMTFDVN-KLTRINISSPGSP-VTAVTDDFKQGQRHTLLVWAPNHYQ----VVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANI-SSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQ-RKNDS---CPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVG-----NIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDE----DEKKNR---------LEKSNPYFMSGAN---------SQKQM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JSS5-1", "uniprot_id": "A0AC58JSS5_DANRE", "id": "A0AC58JSS5-1", "name": "Solute carrier family 15 member 1", "aln": "-------------------------------------------------------------------------------------MNEASLHLTILSPVDQKTVSVGGVTMADKEGHKQKKERASCFGYPVSIFFIVVNEFCERFSYYGMKAVLVLYFK--------YFIGWDDDLSTTIYHTFVALCYLTPIMGAIIADSWLGKFKTIVYLSIVYTIGQVIMAISAIHDITDANRD--------------------GKPDNKTLHISLSMLGLILIALGTGGIKPCVAAFGGDQFED----------------HQEKQRSTFFSIFYLSINAGSLLSTLITPILRSQECGIYAKQSCYPLAFGVPAALMVVALIVFVIGHKMYIM-ESPKGNILLQVINCIGFALNNR--------------FRHRGKQYPKREHWMDWAEEKYDKLLIAQVKMVVKVLFLYIPLPMFWALFDQQGSRWTIQATTMDGNFG-----------------GFVIQPDQMQIVNPILIVIMVPIMDSAIYPLIKLCR-INFTPLRKMTVGMVLAALAFVAAALLQLQIDET-MPKFPST-SQTQLKFLNVESTSLPVVVEGQDQ--FMVPGFN--------------------------ASSEYLTLDKE-NVT----ISAG---GVNDTAFLKTGTRHTVLMN-AAGMR----NTLDDLTEKPEQGLNAIRFVNGWENRLNVSVK-SDNVHA-DPLDASVYLLVPHGKVNFTIFD-GGDGKCHYIMQ---LGFGSTYTVLIPSTFAFGQTCSESFEAVQDMEPNRIHMAWQVIQYFLLTCGEVVYSVTGLDFSYSQAPSNMKSVLQAGWLLTVAVG-----NIIVLIVAEAGSLPDQWAEYLLFASLLVAVSIIFAIMAYFYTYIDPNEIEAKFKELEPEDKKRKEMQ------MTAKDNMAYVHNEN------TNIKQTKI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GFH5-1", "uniprot_id": "A0AC58GFH5_DANRE", "id": "A0AC58GFH5-1", "name": "Solute carrier family 15 member 1", "aln": "-------------------------------------------------------------------------------------MPDS--------------------KMDETK--KKKKKTAECCGYPISIFFIVVNEFCERFSYYGMRAVLVLYFR--------YFLLWDDDLATSIYHAFVALCYLTPILGAIIADSWLGKFKTIIYLSIVYAVGQVVMAVSTIHDITDANRD--------------------GTPDNFTLHIALSMLGLVLIALGTGGIKPCVAAFGGDQFQE----------------HQSRQLNTFFSVFYLCINAGSLLSTLITPVLRAQECGIHTQQQCYPLAFGVPAALMVVSLVVFIAGSGMYTK-TAPEGNIMGSVCKCIWFALNNR--------------FRHRSDIYPKREHWMDWAEEKYDKLLIAQIKMVLKVLFLYIPLPMFWTLFDQKGSRWTLQATTMTGDFG-----------------GFVLQPDQMQTVNPILILTLVPIMDRIIFPLIKKCG-LNFSPLKRMTVGMLFAATAFIAAALVQMEIDKT-LPNFPSS-SESQLKVVNMHSESLIVTVPSQEP--LLIGSFEVQHTSKHTTAVSHWCFTISSHVVFPQSSPDYITFDQQ-DIR----LAFNTTPEINKDLSLIKGSRQTLIIPSEPAEM----YLKEDIKSKPKEGKNAVRFVNGWTAYLNITNL-ESSLQ---PSETSNYTLVSQGMRKFTLTD-GIQS-CEFSRK---FGFGSSYTFLIPSDLFS--TDCESIKEIEDMQPNSVHMALQIPQYFLITTGEVMFSVTGLQFSYSQAPKNMKSVLQAGWLCTNAVG-----NIIVLIVAELGKLPKQWAEYVLFASLLVAVSIIFSIMAYFYTYIDPAEIEAEILKQQETDPDKK----------KKKETLEMEEKENE-----QEIKQTKI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ES07-1", "uniprot_id": "S15A2_MOUSE", "id": "Q9ES07-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------------------------------------------------MNPFQKNESKETLFSPVSTEEMLPGPPSPPKKSTPKLFGSSYPLSIAFIVVNEFCERFSYYGMKAVLTLYFL--------YFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGK-----------------------------MLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEE----------------EHAEARTRYFSVFYLSINAGSLISTFITPMLRGDVKCFG--EDCYALAFGIPGLLMVLALVVFAMGSKMYRK-PPPEGNIVAQVTKCIWFAICNR--------------FRNRSEDIPKRQHWLDWAAEKYPKHLIMDVKALTRILFLYIPLPMFWALLDQQGSRWTLQANKMDGDLG-----------------FFVLQPDQMQVLNPFLVLVFIPLFDLVIYRLISKCG-VNFSSLRKMAVGMILACLAFAVAALVEIKINGM-IHPQPAS-QEIFLQVLNLADGEIEVTVQGNRNNPLLVESISSFQ-----------------------NTTHYSKLRLETKSQDLHFHLKYNNLSVHNEYSVEEKNCYQLVVHENGES--LSSMLVKDTGIKPANGMTAIRFINTLHKDMNISLDANAPLSVGKDYGVSEYRTVQRGKYPAVHCETEDNV---FSLNLGQLDFGTTYLFVITNITNRG----LQAWKAEDIPANKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVG-----NIIVLIVAQFSGL-VQWAEFVLFSCLLLVVCLIFSVMGYYYVPLKSEGIHEATEK--------------------QIPHIQGNMINL-------ETKNTRL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63424-1", "uniprot_id": "S15A2_RAT", "id": "Q63424-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------------------------------------------------MNPFQKNESKETLFSPVSTEEMLPRPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFL--------YFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGK-----------------------------MLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEE----------------EHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFG--QDCYALAFGVPGLLMVLALVVFAMGSKMYRK-PPPEGNIVAQVIKCIWFALCNR--------------FRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLG-----------------FFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCR-INFSSLRKMAVGMILACLAFAVAALVETKINGM-IHPQPAS-QEIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQ-----------------------NTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGES--ISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKV---FSLDLGQLDFGTTYLFVITNITSQG----LQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVG-----NIIVLVVAQFSGL-AQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDK--------------------QIPAVQGNMINL-------ETKNTRL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16348-1", "uniprot_id": "S15A2_HUMAN", "id": "Q16348-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------------------------------------------------MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFL--------YFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQ-----------------------------VVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEE----------------KHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFG--EDCYALAFGVPGLLMVIALVVFAMGSKIYNK-PPPEGNIVAQVFKCIWFAISNR--------------FKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLG-----------------FFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCG-INFSSLRKMAVGMILACLAFAVAAAVEIKINEM-APAQPGP-QEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQ-----------------------KTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNS--ISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKN---FSLNLGLLDFGAAYLFVITNNTNQG----LQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVG-----NIIVLVVAQFSGL-VQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADK--------------------HIPHIQGNMIKL-------ETKKTKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6T2-1", "uniprot_id": "S15A2_DANRE", "id": "B0S6T2-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------------------------------------------------MGKMKDKD--------VDAEKYEKAQRSP------KLCGTNYPVSIAFIVVNEFCERFSYYGMKAVLTLYFM--------NYLHWDKNLSTAIYHAFSGLCYFTPLLGALIADSWLGKFKTIIYLSIVYVIGHVVKSVGAIPDVGDS-----------------------------TVHIALSMVGLGLIALGTGGIKPCVAAFGGDQFDE----------------DNIDERRKFFSIFYMSINAGSVLSTIITPILRGDVQCFG--GDCYALAFGVPAALMVIALVVFISGSGLYKK-SPPEGNVLVRVCKCIGFAISNR--------------WTN-SKKSPKRSHWLDWAEEKYSKRLIQEIKMVCRVLVLYIPLPMFWALFDQQGSRWTLQATRMNMDFGG----------------GFIIKPDQMQMLNALLILVFIPIFDMGIYPLVGLCR-IKLTPLKKMATGMILAALAFCAATAVEVYVIKT-VVEPPPA-KESLVQVYNLMDSDVTVQFPAHN---VFSEPLKPYE-----------------------EPSGYSSLPLTGESQLQNVVVSHNGMNYQCRLTFTERMAYSLLLHPTAQHNGSVCNLVKDHITKSETGAAYIRFINTHTENINVTVGT-EEVHASANYGISRNISVPRGEYNKAVCVTDTKE---YEINLGLLDFGAFYTVILSEAGNN-----LAVKKMEDIQANNIHIGWQIPQYVFLTAGEVMFSITGLEFSYSQAPASMKSVLQAGWLMTVAFG-----NVIVLIVAEGAGM-EQWVEFLLFAALLVAVSIIFSIMAYFYTYVDPDQLDKLFKEDGD---------------GGKVESSKKDELSLG-----DMPKQTKM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCG8-1", "uniprot_id": "X2JCG8_DROME", "id": "X2JCG8-1", "name": "Oligopeptide transporter 1", "aln": "MELPAEQVPLLEIQPAAEPVAEPEPSPAAEIAPASPDGSGPSAAAAEEVTPSVATVEDTTPIAAPAESQPSGESNGTAEAKKLPEIAKKNGKEPDQNDKEPDQNGKELAETNDFKNVSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVLVLYLS--------RVLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAIGPLNLP-------------------------------METFTMLGLALIALGSGGIKPCVSAFGGDQFKVP---------------EQVKQITSFFSLFYFSINAGSLISTTVTPILREDVSCFD-DINCYPLAFGVPAVLMIVSVIIFVLGRSLYKM-KPPAGNMVVLVSSTIWTALTTK--------------CKEKKTNP--REHWLDYADKKYDRQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMG-----------------SWDIKPDQLQVLNPLLILIFIPLYDVALYPALKLVG-IRR-PLQKLTMGGILAGIAFIISGVVELSLEKT-YPDLPYS-QNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYT-----------------------NKDIYAPGSLDVEFSLSSASEACTISADKIPKVLTDNTAWSLFLNPLNGSG---YYWEEDFVDKPSQSHPLIRNVANVPQELSIRWEKASTGEVVYD-DLASKTLLTRVNSAEYVVMVGERNVGTFDVHT-----GGVYTLLIK-DNNNI----YEANLEEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFG-----NVIVVVIAEAALFESQASEFFLFAGLMFADMLIFMVMAYYYVPNDPNK-VEEAQPLTAGDAKTEIP---------ALEGGVENK-----------GKDINE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91679-1", "uniprot_id": "PEPT1_DROME", "id": "P91679-1", "name": "Peptide transporter family 1", "aln": "--------------------------------------------MASEIT------------------------NG------------KNG-----------QNGK-----NGQKEESDSQ-IAPPIPYPKSVAFIISNEFCERFNYYGMRTILVLYLT--------NKLGYNEETATVLFHTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSGMP-------------------------------TKAVTVVGLLLIAIGTGGIKPCVSAFGGDQFSLP---------------AQSFQLAKFFSLFYFAINAGSLISTTFTPILRADVHCFG-DQDCFSLAFGVPAILMIFSVIIFMAGKRLYRC-QPPAGNMIFGVSRCIADAFKGW--------------QKRRHSEP--MESFLDYAKPTVGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVL-----------------GFQIKPDQMQVVNPLLILGFLPLFDYIIYPALARCG-IRR-PLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPRVIEP-LNVWE-----------------------DLSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFA---DGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVASFEAKE-----GRLYSILVTGSARDG----YQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIG-----NMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKATTVDTTARKTNGIEAEPGYGAYRNHAYDNDFSEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O09014-1", "uniprot_id": "S15A4_RAT", "id": "O09014-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------------------------------------------------------------------------MEG------ERAPLLGSRR--AAAAAG-VFAGRRAACGAVLLAELLERAAFYGVTANLVLFLNG-------APFNWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPRSRSFLCGDPHPELVRNCSAPFPNGTAVCPDAAARRCAPATFAGLVLVGLGVATVKANITPFGADQVKD----------------RGPEATRRFFNWFYWSINLGAILSLGGIAYIQQN--------VSFLTGYLIPTVCVAIAFLVFLCGQSVFIT-KPPDGSAFTDMFRILTYSCCSQ-RGGQRRS-GEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLKIPEISSITT-----------THHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHG-LLPSSLKRIAVGMFFVTCSAFAAGILESKRLD--------------------------------------------------------------------LVKEKTINQTIG----------------------------------------------------------------------------------------------------------------------------------------------------GVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDR--------------------QRARTDGGTASTRT-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W98-1", "uniprot_id": "S15A4_MOUSE", "id": "Q91W98-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------------------------------------------------------------------------MEG------ERAPLLGSRRPAVSAASA-VFAGRRAACGAVLLAELLERAAFYGVTANLVLFLNG-------APFDWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGLLAFPLLAAPRSRSFLCGDPRPELVRNCSAPFPNGSASCPENAARRCAPATFAGLVLVGLGVATVKANITPFGADQVKD----------------RGPEATRRFFNWFYWSINLGAILSLGGIAYIQQN--------VSFFTGYLIPTVCVAIAFLVFLCGQSVFIT-KPPDGSAFTDMFRILTYSCCSQ-RGGQRRS-GEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITT-----------THHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHG-LLPSSLKRIAVGMFFVMCSAFAAGILESKRLD--------------------------------------------------------------------LVKEKTINQTIG----------------------------------------------------------------------------------------------------------------------------------------------------GVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDR--------------------QRARTDGGPASTRT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N697-1", "uniprot_id": "S15A4_HUMAN", "id": "Q8N697-1", "name": "Solute carrier family 15 member 4", "aln": "------------------------------------------------------------------------------------------------MEGSGGGAGERAPLLGARRAAAAAAAAGAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNG-------APFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCG----------SARLLNCTAPGPDAAARCCSPATFAGLVLVGLGVATVKANITPFGADQVKD----------------RGPEATRRFFNWFYWSINLGAILSLGGIAYIQQN--------VSFVTGYAIPTVCVGLAFVVFLCGQSVFIT-KPPDGSAFTDMFKILTYSCCSQKRSGERQSNGEGIGVFQQSSKQSLFDSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITT-----------TPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHG-LLPSSLKRIAVGMFFVMCSAFAAGILESKRLN--------------------------------------------------------------------LVKEKTINQTIG----------------------------------------------------------------------------------------------------------------------------------------------------NVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSHTDFGNINGCYLNYYFFLLAAIQGATLLLFLIISVKYDHHRD----------------HQRSRANGVPTSRRA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BPX9-1", "uniprot_id": "S15A3_MOUSE", "id": "Q8BPX9-1", "name": "Solute carrier family 15 member 3", "aln": "------------------------------------------------------------------------------------------------MSAPR--AEEQPSRSGERQPLVARGPRGPRRWRRTAAAAVLLVQMLERAAFFGVTSNLVLYLNS-------LNFNWDGQQASRATLLFLGASYLLAPVGGWLADVYLGRFLTISLSLLLYLAASGLLLTTITNDGRRSFCG-EMPELPLEPACPSSSCQGSWS---SPYCATTLYLVLLLLALAASSVRSTLTSFGADQVMD----------------LGRDATRRFFNWFYWSINLGAILSLLVVAFIEQN--------ISFLWGYSIIVGLVGLAFFIFLFATPVFIT-KPPTGSQVSSMLKLAFQNCCP----CRRSS-------SRDSESAHLLPDQRSNQPGPSPQEDMANFQVLVKILPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFRTNP-NISLLLRSDSSNYRIPEAWLLLANVAVILILIPVKDHLIDPLLLRCK-LLPSSLQKMALGMFFGFTSIIVAGVLEKERLQY-------------------------------------------------------------------IAANQTVPQLIG----------------------------------------------------------------------------------------------------------------------------------------------------KDLYYAAPLSIWWQIPQYLLIGVSEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSGLVALLSFPG-GWMYCPKDFGNINNCQMDRYFFLLAGIEAVTAVLFLWIAGRYERTR------------------QDPASQRSSSRVRG-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924V4-1", "uniprot_id": "S15A3_RAT", "id": "Q924V4-1", "name": "Solute carrier family 15 member 3", "aln": "------------------------------------------------------------------------------------------------MSALR--AEQQPSRSGERQPLVAQGRWGPRRWRRTAAAAVLLVEMLERAAFFGVTSNLVLYLNS-------LNFNWDGEHASRATLLFLGASYLLAPVGGWLADVYLGRFLAISLSLLLYLAATGLLLTTITDDGRRSFCG-EMPELPLKPACPSANCQGSWS---SPYCATTLYLVLLLLALAASSVRSNLTSFGADQVMD----------------LGRDATRRFFNWFYWSINLGAILSLLVVAFIEQN--------ISFLQGYSIIVGLVGLAFFIFLIATPVFIT-KPPTGSQVSSMLNLAFQNCCPGWQWWRRPS-------SRNSEGAHLLPDQRSNQPGPSPQEDMANFQVLLKVLPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFRTNP-NISLPLRSDSSNYRIPEAWLLLANVAVILILVPVKDHLIDPLLLRCK-LLPSALQKMALGMFFGFTSIIVAGVLEKERLQY-------------------------------------------------------------------IAANQTVPQLIG----------------------------------------------------------------------------------------------------------------------------------------------------KDLYYAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSGLVALLSLPG-GWMYCPKDFGNINNCRMDLYFFLLAGIQAVTAVLFLWIAGRYERTR------------------QDPDSQNSTSRVRG-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY34-1", "uniprot_id": "S15A3_HUMAN", "id": "Q8IY34-1", "name": "Solute carrier family 15 member 3", "aln": "------------------------------------------------------------------------------------------------MPAPR--AREQPRVPGERQPLLPRGARGPRRWRRAAGAAVLLVEMLERAAFFGVTANLVLYLNS-------TNFNWTGEQATRAALVFLGASYLLAPVGGWLADVYLGRYRAVALSLLLYLAASGLLPATAFPDGRSSFCG-EMPASPLGPACPSAGCPRSSP---SPYCAPVLYAGLLLLGLAASSVRSNLTSFGADQVMD----------------LGRDATRRFFNWFYWSINLGAVLSLLVVAFIQQN--------ISFLLGYSIPVGCVGLAFFIFLFATPVFIT-KPPMGSQVSSMLKLALQNCCP--QLWQRHS-------ARDRQCARVLADERSPQPGASPQEDIANFQVLVKILPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFPANPANISVALRAQGSSYTIPEAWLLLANVVVVLILVPLKDRLIDPLLLRCK-LLPSALQKMALGMFFGFTSVIVAGVLEMERLHY-------------------------------------------------------------------IHHNETVSQQIG----------------------------------------------------------------------------------------------------------------------------------------------------EVLYNAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSSLVALLSLPG-GWLHCPKDFGNINNCRMDLYFFLLAGIQAVTALLFVWIAGRYERAS------------------QGPASHSRFSRDRG-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH93-1", "uniprot_id": "Q9VH93_DROME", "id": "Q9VH93-1", "name": "Peptide transporter family 1", "aln": "--------------------------------------------------------------MFRATEIGSEETLPALAELSQVGYERDARDVEWVAWRGERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVFFVLATKFFEAFAANGIRTVLALYLR--------DDLNFTESFSTVVLHIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTSLPAMGLP-------------------------------MVLLVSIALLFIAVGNGSIRACITSLGALQFKLP---------------EQSVHLAEYFSFYYFVYYFGIFLSKILPPLVRANTQCFD-KAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSEKLSDDNILFKFCGCIKTALVEK---------------WRRRKSTKRSNYWLHNAVVAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQMNTTLMG-----------------VTIQPDQAKAVGPIFLFMLIPLWQYITVPLLRRYFNWELQPLHSVTVGGIFSAGAFFCAGALQERIKNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPQTVNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFG-----NLIVVLVTELGMLSSQMAEYFFYAVVMLVCIILYALLAFDYTLQERKAGMYVRMDSEAE----------------DRDVPSTSRSGSI--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32901-1", "uniprot_id": "PTR2_YEAST", "id": "P32901-1", "name": "Peptide transporter PTR2", "aln": "---------------------------------------------------MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVGNR-----------------------------DSAIGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLSLMATTELEYHKG---------FWAAYLLPFCFFWIAVVTLIFGKKQYIQ-RPIGDKVIAKSFKVCWILTKNK------------------FDFNAAKPSVHPEKNYPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELHGIP---------------------NDFLQAFDSIALIIFIPIFEKFVYPFIRRYT--PLKPITKIFFGFMFGSFAMTWAAVLQSFVYKA----------------------------------------------------------------------GPWYNEPLG------------------------------------------------------------------------------------------------------------------------------------------------------HNTPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFLLTNAFG-----SAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMDYEEEDE---------------FDLNPISAPKANDIEILEPMESLRSTTKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * *: : : :: : :: * . .*. ::* *. :: :* . : ::.:. . ::. :: : . *. * :* * . . : : . .: . : . : .. . : : . : : :: : : *. : . :. ::*: : : .: : * .: . : :: : : : .: .*:. *:.**::::: :* .*:. : . :: ..* . : : . : ", "identical_positions": 21, "similar_positions": 109, "identity": "2.16%" }, { "cls_id": "homologset.agr.SGD:S000001802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62987-1", "uniprot_id": "RL40_HUMAN", "id": "P62987-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62984-1", "uniprot_id": "RL40_MOUSE", "id": "P62984-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62986-1", "uniprot_id": "RL40_RAT", "id": "P62986-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18101-1", "uniprot_id": "RL40_DROME", "id": "P18101-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRILAQKYNCDKMICRKCYARLHPRATNCRKKKCGHTNNLRPKKKLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CH09-1", "uniprot_id": "RL40B_YEAST", "id": "P0CH09-1", "name": "Ubiquitin-ribosomal protein eL40B fusion protein", "aln": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************.****:***:******************************************************: **.****** :******** ***.****:******:******:*", "identical_positions": 115, "similar_positions": 10, "identity": "89.84%" }, { "cls_id": "homologset.agr.SGD:S000001803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA98-1", "uniprot_id": "TPR_RAT", "id": "F1MA98-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAAVLQQVLERPELNKLP----------KSTQNKLEKFLAEQQSEIDCLKGRHEKFKVESEQQYFEIEKRLSQSQERLVNETRECQNLRLELEKLNNQVKVLTEKNKELETAQDRNLGIQSQFTRAKEELEAEKRDLIRTNERLSQEVEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVTVKYREKRLEQEKELLHNQNSWLNTELKTKTDELLALGREKGNEILELKCTLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDLLSATKRKGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSAKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLFALRELGETREREEQETTSSKIAELQNKLENSLTELEQLRESRQHQMQLVDSIVRQRDMYRILLSQTTGMAIPLQASSLDDISLVSTPKRSSTSQTVSTPAPEPIIESTETIEAKAALK-------QLQEIFENYKKEKMDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATLKQHLNNMEAQLASQS----TQRTGKGQPGDRDDVDDLKSQLRQAEEQVNDLKERLKTSASNVEQYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLTELKKTLSSVQSEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDLEKQNRLLHDQIEKLSDKVVTS----------------MKEVVQSPLNISLNEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQNLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLINQQKDPDTEEYRKLLSEKEIHTKRIQQLNEEVGRLKAEIARSNASLTNNQNLIQSLKEDLSKVRTEKESIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEELKAQQ-KAMETSTQSSG-DHQEQHISVQEMQELKDNLSQ-SETKTKSLEGQVENLQKTLSEKETEARSLQEQTAQLQSELSRLRQELQDKTTKEEQLRQQMNEKDEKTWKAITVARSKIAHLSGVKDQLTKENEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-TNKAPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGSTSGSVRSTSPNVQPSISQPLLTVQQQTQATAFVQPTQQSHPQIEPANQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRAREEEEDSTIEAGDQVSDDTVEMPLPKKLKTVTPVGTEEEVMAEESTDGEAETQTYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQ-TTSSQDG-QGKGDDVIVIDSD------DED-DDEENDGEHEDYEEDEDEDDDEEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGAESNQRAADSQNSGEGNTSAAESSFSQEVAREQQPTSASERQTPQAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETPAGDDGDEVFV-ETESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGISHAMGGRGGINRGNIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6ZDS4-1", "uniprot_id": "TPR_MOUSE", "id": "F6ZDS4-1", "name": "Nucleoprotein TPR", "aln": "MTSGGSASRSGHRGVPMTSRGFDGSRRGSLRRAGARETASEAADGAAPAAGLRASPCSLASPSAAAAVAAIPADMAAVLQQVLERPELNKLP----------KSTQNKLEKFLAEQQSEIDCLKGRHEKFKVESEQQYFEIEKRLSQSQERLVTETRECQNLRLELEKLNNQVKVLTEKTKELETAQDRNLGIQSQFTRAKEELEAEKRDLIRTNERLSQEVEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVAVKYREKRLEQEKELLHNQNSWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDLLSATKRKGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKQENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSAKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLFALRELGETREREEQETTSSKIAELQHKLENSLAELEQLRESRQHQMQLVDSIVRQRDMYRILLSQTTGMAIPLQASSLDDISLLSTPKRSSTSQTVSTPAPEPVIDSTEAIEAKAALK-------QLQEIFENYKKEKIDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLNSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATLKQHLNNMEAQLASQS----TQRTGKGQPGDRDDVDDLKSQLRQAEEQVNDLKERLKTSTSNVEQYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSTVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMTSIRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDLEKQNRLLHDQIEKLSDKVVTS----------------MKDAVQAPLNVSLNEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNVEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQNLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQQLINQQKDPDTEEYRKLLSEKEIHTKRIQQLNEEVGRLKAEIARSNASLTNNQNLIQSLREDLSKARTEKEGIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEELKAQQNKAMETSTQSSG-DHQEQHISVQEMQELKDTLSQ-SETKTKSLEGQVENLQKTLSEKETEARSLQEQTVQLQSELSRLRQDLQDKTT-EEQLRQQMN---EKTWKTLALAKSKITHLSGVKDQLTKEIEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-TNKAPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGNASGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPTNQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTMEAGDQVSEDTVEMPLPKKLKMVTPVGTEEEVMAEESTDGEAETQAYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQ-TTSSQDG-QGKGDDVIVIDSD------DED-DDEENDGEHEDYEEDEDDDDDEEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGAESHQRAADSQNSGEGNTSAAESSFSQEVAREQQPTSASERQTPQAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETAAGDDGDEVFV-EAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGISHAMGGRGGINRGNIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12270-1", "uniprot_id": "TPR_HUMAN", "id": "P12270-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAAVLQQVLERTELNKLP----------KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGA-ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALK-------QLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS----SQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVAS----------------VKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSG-DHQEQHVSVQEMQELKETLNQ-AETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER---ELREHQERHLEQRDEPQEP-SNKVPEQ-----QRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQS-EGPVEHVPVFGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSSQDG-QGKGDDVIVIDSD------DEEEDDDENDGEHEDYEEDEEDDDDDEDD----TGMGDEGEDSNEGTGSADGNDGYEADDAEGGD-GTDPGTETEESMGGGEGNHRAADSQNSGEGNTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQ--MTRRQSVG-RGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPED-MPQTSSSHSDLGQLASQGGLGMYETPLFL-AHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETATGDDGDEVFV-EAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSS-VDTSSSQPKPFRRVRLQTTLRQGVRGRQFNRQRGVSHAMGGRGGINRGNIN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ68-1", "uniprot_id": "A0A8M3AQ68_DANRE", "id": "A0A8M3AQ68-1", "name": "Nucleoprotein TPR", "aln": "--------------------------------------------------------------------------MAALLQQALERTEVNKLP----------KAIQNKLEKVLAEQQTEIDSLISQHERYKADCEQQYFNLEKKLAESQEQFLSQSKDYHNIKEENNRLVEELKKLKEIEEVQGTTQE------SKPPRAKYEIEAENRELSRLLEKRSQEVENLSEDLKRLNDKLVETNTIKMELQLKLDELQSSEVSIQYREKRMEQEKELLQNQNTWLNTELKSKTDELYTVSRDKGKENLELRCSLESKKEEVTRLQDQVNTLKKANDSMQKSTEDLMRKLKEAKEQRASMEEKYRNELNANLKLCNLYKGAASDSEAKNTELNRAVEELNKLLKEAMEANKGTEKKLSELQSVREKAESDLREKVRHLEKELENSNTRLADFKRRGVPALTEEELTNLSPTAAAVAKIVKPGMKLMELYNAFVEAQDQLHLEKLENKRVNKVLDEIVLEVETKAPILKRQREEYESMQKSMTSLCYKLEQAMKEVHRLQKETDEANKRALVLERDNQKSERQLADMSEQVRVLLVEVEEARGNQVVR-EDVSSA-VSSSSEVQGSRQVAFRSIQELQQQNQNLLVKIRDLEEQREKDQNQAKSAKQTELEQSLEKVQKELEQIKEQQNHQKLLAESAIRQRDMYRILL-QTAGVELPPQGS--DGGSQSTTPSRPGPMATRSTPLRAAAAESFQATQSKAALK-------QINDAFTTYKKEKAENDKLLNEQIERLRGQVSDLLSQKAKLSSQLEFASKRYDMLQENVNGFRRETEALRERNQKMSATHQRHEQIIHTMTQDLREANEKLTMSESRAENIRKERDILKQVENRLNQEKESILTEQRSQNLLLTNLKSIQLTMERSETETKQRYNNQIQHLEKEIIQLKKRLEQEVEQRHALERNQDTQLLEAKKKLESQTALHQKTKELLRSAEQQVTSLRQQLNNNENQSAAPKQPVRTLPRVSAPSVPQQEADDLRARLQQVEEQNSDLKERLKNTTTNVEQYRSMVLSLEESVNKEKQLAEQARTSTDNQLKMARELNQQLEARLVEAEKEKLELQQEKMKAVDSVEERVKELKRSMTNMQTELQEALQRSTAAVTQEQKATQDSKVQAKLAAEAQNKYERELMLHAADVEALQAAKKQGLLLTQNMKQLEEKAQKAASELHQYRTDWVMQEKRLKETLSKEQKRAEELQKQNTLLHEQMENLSSKITAST---------------QQETGESSLNISLNEEGKSHEQILDILRFVRREKEIAETRLEVAEVETLRYKQRMEYLECELKELQDSLNVEREKLQVTTKTLVQQEETMKRMESMSALTETNKMLKNEKNRLEHELQQTQAKMRKLEADIKPLQEANGELSEKSGMLQAEKRLLEEDVKRLKSRTQQLLNQQKDSDQEESKKLHSERETHLKRIQQLTEETGKLKNEVARSQASITTAQSQVQNLQDSLGKVTTERDSLKKELEAKTLDIQEKVKTITQVKKIGRRYKTQYEELKEQHDKMVAEAASKPAQEQEDRQASVQEIQNLKSSLSQ-TQNRTSELETQLDCIQKTLQEREAEVKSLQEQLTQVQPELSRLKAELQDKGKLEEQLRQQIADKEEKTKKAFLGAKQKLNQLNSAKEQLAKENEELK-------LQREELEVRMSALKSQYEGRLSRQERELRELREQQERHGEQRDEAQEPGQSKVQEAPRSSDARQITLKPTPAAD-RGSASQSEPPTANIKPTLVAATPSKP--SPIAGSKSTPKASIRPMITPAPVT----TPTATVMPTTQVETQEALQSTEGPLEHVTVFGSTSGSVRSTSPNIQT--TQPILSLQQ-SQATAFVQPTQQ------QASQEPATSIMEAVHSSQMERPSTSTAVFGTVSATTGSSVAKRVREEHEESSTEVTDTTQDDSTHPPIMKKLRIVRRVGLEDASGTEESNDAMGESSGDVQQPPD-----ASEEAYPVLGEGDEESLSVPMDQVSESQPSESQISGQDSSEEYKHDVIVIETDSATEEEEEEEEEQEEPGQYEDDDEDEDDDAEDEDDEDGDGGMAEAAEESNEGSGSADANEAYEGDEAEQGAGEADPSVHNEESQEASDSTQKQPDSQSSEASVSTLEAFPLEPVREHPPLPSTTTTSLAPRLPQSPRRPHHTPPPRLNIHPVP-ELGPPIMQRQSGQSRRPSMS-RAPQLTPGIG-SMQHFFDDDDRMVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMMPQASSSHSDLSHLATHGGLGMYESPLFLPTHDEESGGRSVPTTPLQVAAPVTVFTESHPSDVSETASQSVPMVSTSTASLSAPGEAVPGDDGDDVFVAEAESEGVSSEACLEG--QLELDSAQPADDASLPSTSQEPTSSSADTSTSSGQAKPAGRLLPQHHLPR----RNQLIRRGFPRGGRGRG-LSRGSPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8P9-1", "uniprot_id": "TPR_DROME", "id": "A1Z8P9-1", "name": "Nucleoprotein TPR", "aln": "----------------------------------------------------------------------MDLSGPQTLNNILQPDELKLVP----------EDVQKKLSEYINN-FSDEYCKNRAAANRLAEAEQKKEELENKMEDYLVKFTSFELNVNELRTHLDQMSSERVNLMDTIAKGEQTIS-------QLRKEKASVVEERDSMMKVIERQQAELERLKQDLHTYQQQLSSAIAAKCEAIARVDEIQSKEVALELKENRMESERDMLHKEILLISGDLNKSNAELQNIRREHTINTMQLQSCLKEKTESLKLMQEQYEQAVKTIGELTSKIEMQNDTAFKQNQATEEYVGKLKKELDAKEKLFEIFKSTESDHLIQREELLQGISEIKRLLEEAEEQCAQLTEQMETMKQKHSAELDEQNKKIQAMEQELASANDLLKQARESNL----ESAICQLAPSAAVASRLIRSDLSLTELYSMYAKSSEELEMRNCEIEQLKLQLKSIIAEISESAPILEKQNSDYQKMKETNSELLREHDELLQNKLCLERELERALSTLNHNQNENKKLKQTHTDLSRQVCMLLDELNCIRAG-VKHVRIQPTRQLPTSESLISDNLVTFSSIEELVDRNTYLLNMSRELTELLEASEKNQDKMLLEQSKNHIRKLDARFAELEDLLTQKNNTVTTLLSKCDRYKKLY-FAAQKKLGQNTVDLDDSNLEPNDSALDTSEQPAANFEESRKLEKRVRQLEQQLEGEVKKYASLKENYDYYTSEKRKNDALAQEQFDSMRKEVRELTSSNCKLMNTTEFQKEQIELLHKNIGTYKQQVTTLEERTKNYEKTIIKHEQTVHLLKDEMMAAHRKHAAADAEAQSLRQENRILRDTSSRLQIEKETYHREQQSQSLLLNSLEFIKTNLERSEMEGRQRLEQRLDDTVRELAAQRRHFQEEEEKFRESINEFKRQAETAIKLKDEEKQLADKWQAELTSVREELAEKVNKVNELSKKLQEVLT---PTLNDNPITAANKRAREFELKLDQATVEIESLTKELAKTREHGEQFYKMSQSAESEIKRLHELHGELVAKQEEEIKKLRSSEAELKTRISDLEAEAMLSN-------VTEQSKTVNQSGQLKSAQDDLKSLLEKLTEANCTIRTLRSENTSLVESLNAAEVKYANGMIQHSADIQELTRYKAEFFKANDELNQLKSGRESLQAAYDELLRSNAEAQKLLDKEREESEKRVADLHALNSNLHDQIEALASKLAVLASQSQNPNSSLNESAMDGDQSLNASGLTAAEEGRNNEQLLKIIKFLRKEKDLFAAKLDILKAENARLISEHAIQQKKVDELNGYLNQERAKSQTDVVSANKHEEVLRKIETLNAITDSNRILREERNALTLRVAELTDRISSVEKELFPLQCSNKELTSKIEEINVENTSLRTEAIKWRQRANALVEKS-NRNPEEFKRLQAEREHLAKLLTAEKELNKKQSDELTVLKQRMNTEIPMLNKQMQILDEARK------KQVDEFTNLKQNNTRQTQDIMELKNRLLQKEEELLKANEELETKDKTIADKETKELQLRKLAKRYKDFYIGLQSQGGGTESAAELEKVRSELEEVNNQLRALKDEHEKITKECDEVKKRT-EPETDTSAIRQEYKAKLDKLVVDLTVARTDLVN----------------------------QETTFAGTKSSYDETIARLEKELQENIAANKDINQRLTRENESLHMRINQLTRQLGSQQSTKPSTSSVAEKGNISESSPRTANVKPMSGSATVQQSATVTPWRGGETPLASIRPISVQNSRTAAILPTSQQPPAGSSTSTSSSSSSSSTSTTSAAGGGSSAVAQTALVPPQQQVHTTGSAALESMASSSPTSSHTDY------MPSTSSASVAVAAIPPMGASSAAESSQEAESIQHPQQNDSQLFVGGAQQQVVALVSPRVEGSSSSSSSTSVPTATAPSIQDGGSQSQQPSTSGSSSSSSTVVSSHSRHTPSSSNVTTTQAGCSSQGIKRPRDIEGDSSTGTEEGVAEKMSKITKRLRGPMHSG-------ELSAGHIGDSGMDVDQMPTSSQRDQEDD----IQVVDSDDEEDVLADADDGPIDGGEAEQEGYEDSYEQDNEMDDNEGGDDDNDIAVDAQDNNEVDIEVPEQHMQAQEESQSLDNQAIATASASTQENNQSQAITSGSGESSNPVTLPQAEASNWKQAAASTSTAAARRNESSVEIVSSPQVSNFCEQPARLESAEVDGTAEVAGGAPHESAGPSDTGAASASS--PQKQSEAGESSGSDALKAADDGGDHADGTDNAR-EADEAFAEETMATGQGEDSQPLGNDNPNVGTSQSEVSHNQANLGEGNPTEDSEGADGVSSEGEKQAVGVEEEGREAEATSPSENTRFRTLRSAVPTRRGHRAMRGGSPNSQNRPQRIVWQRDTSPGNIQQNQMSANNNRFAQRTRNRRPIRRPPPNNFNNGGRFP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02455-1", "uniprot_id": "MLP1_YEAST", "id": "Q02455-1", "name": "Protein MLP1", "aln": "-------------------------------------------------------------------MSDHDTPMESIQNGENSDERLNAIASFFGCSLEQVKSFDGDVVKHLNDKLLQFNELKSENLKVTVSFDELKASSLKKIDGLKTEMENVIRENDKIRKERNDTFVKFESVENEKMKLSSELEFVKRKLDDLTEEKKETQSNQQRTLKILDERLKEIELVRVENNRSNSECKKLRSTIMDLETKQQGYITNDLNSRTELERKTQELTLLQSNNDWLEKELRSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMERTNNDVLKQKNNELSKSLQEKLLEIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLN-AVKEELNSIRELNTAKVIADDSKKQTPENEDLLKELQLTK--------EKLAQCEKECLRLSSITDEADEDNE----NLSAKSSSDFIFLKKQLIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLEHTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEIQFIQNIMQEDDSTITE---------SDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSV---------------------PNEDASYSNVTIKQLTETKRDLESQVQDLQTRIS--------------QITRESTENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKSKLSIVETELLNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEEDNNSNIEWYQNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKEIEEDK-----------IRLHTYNVMDETINDDSLRKELEKSKINLTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLENALKENEKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVN------------------------------NSTNGPGLNNILITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALKYSMQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEELENKERQGAEAEEKFNRLRRQAQER------------------------LKTSKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGN-------NQLEAIRKLQEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDKIKFIKEKTQEVN-----------------------------------------------EKILEAQERLNQPSNINMEEIKKKWESEHEQEVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKIREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSMEQSGEIDVVLRKQLEAKVQEKQK---------------------------------------------------------------------------------ELENEYNKKLQEELKDVPHSSHISDDER------------------------DKLRAEIESRLREEFNNELQAIKKKSFDEGKQQAMMKTTLLERKLAKMESQLSETKQSAESPPKSVNNVQNPLLGLPRKIEENSNSPFN----PLLSGEKLLKLN---SKSSSGG-----------------FNPFTSPSPNKHLQNDNDKRESLANKTDPP-THLEPSFNIPASRGLISSSSTLSTDTNDEELTSNNPAQKDSSNRNVQSEEDTEKKKEGEPVKRGEAIEEQTKSNKRPIDEVG--ELKNDEDDTTENINESKKIKTEDEE-----EKETDKVNDENSI-----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:: :. : : .: : : : : . .. :: . ::: .: . : ..:: . : : : : . . . * . :. : :. *:* : : : :.: . : : : : :.:: . . :* .* :*:.: :. :*.... : :. :::: *: :.. . : : : . : .: . : *:. : :* :: :. . : : : :. : : .:: : . : :: : :*: *:* . . . : : :::: . .* . :* . : .: . : *:. * :*:: .: : : : : :: * .: * : : .: :: :: . : . . *..: .. * : .* :* ::* ** *:* : * .::: . . :.. : :.. . : : : .. . . . .. : : :. . *. .. : ::::: : . :: . * . : .:: .:* ..: : : *.:* . * :::. : :: .: * : : . .:::*. : . .*. : :. *: . :::..*: :: * * :: ..:::. : ::. .:: .: : .: . : . : . : . . :: ::.. . : . : . . : .. . .* : : ::: : : ...::: :. : . .:* . : .*: :: : : : :.. : . :. * : :. : : . *: :* . : *: : : : : : *: :. : . :. * . . * :* * *::*:: : :. . : .*: :*:*::: ::. : : : .. : ::.: . *: .* : : :::: :.: : :. : ::* *::* : : .: .:: :: *:: *. . : * . :. : : * : ::.: : . .: .:* :* * : : . . . :. . :. :. .. .: . . . .* : : . :. . . .. :. : : *::: : ..:: : . . : :. :: : : . : *: :: . . :: . : . . : . .. .:: .. . : :: * : : ... .::: . : . .. :. . :. : : . . . . : : : . * . . . .. * . .. .: :* . .. .* .. : . .: . . .* . . .. . :. . * * . ", "identical_positions": 83, "similar_positions": 601, "identity": "3.31%" }, { "cls_id": "homologset.agr.SGD:S000001806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BW70-1", "uniprot_id": "UBP38_MOUSE", "id": "Q8BW70-1", "name": "Ubiquitin carboxyl-terminal hydrolase 38", "aln": "MDKILEGLVSSSHPLPLKRMIVRKVVEFAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSVDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPVLCARLSDLLTDFVQCVPKGKLSVTFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSTLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPSEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEAS---RPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRVQSSHKPSEGLDCAETCLQEVTSKVAVPTESPGTGDSEKTLIEKMFGGKLRTHICCLNCGSTSHKVEAFTDLSLAFCPSP------------SVEDLSFQDTASLPSAQD-------------------------DGLMQTSVADPEEEPVVYNPATAAFVCDSVVN-----------------------QRVLGSPPVEFHCAESSSVPEESAKILISKDVPQNP-----GGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDINENLPKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMCPQSESLALAPSQSCLLGVESPNTVIEQDLENKEMSQEWFLFNDSRVTFTS--FQSVQKITSRFPKDTAYVLLYKKQSRANGIDSDNPASGVWANGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCS-FRPNGFD-----DNDPPGSCGPTGGGGGGGFNTVGRLVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8K5-1", "uniprot_id": "D3Z8K5_RAT", "id": "D3Z8K5-1", "name": "ubiquitinyl hydrolase 1", "aln": "MDKILEGLVSSSHPLPLKRMIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPLLCARLSDLLTDFVQCVPKGKLSITFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSNLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTRALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPTEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEAS---RPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRIQSSHKPSEGLGCTETCLQEVTNKVAVPSESPSTGGSEKTLIEKMFGGKLRTHICCLNCRSTSHKVEAFTDLSLAFCPSP------------SVEDSSFQDPASLPSAQD-------------------------DGLMQTSVTDAEEEPVVCNPAAAAFVCDSVVN-----------------------ERRLGSPPVEFPCAKNSSVPGESAKILVSKDVPQNP-----GGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTS-LSSLSEGWSADADFTDVNENLAKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMRPQSESLSLTPSQSSLLGGESPNTVIEQDLENKEMSQEWFLFNDSRVTFTS--FQSVQKITSRFPKDTAYVLFYKKQSRTNGVRSDNPASGVWVNGEPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCS-FRPNGFD-----DNDPPGSCGPTGGGGGGGFNAVGRLVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NB14-1", "uniprot_id": "UBP38_HUMAN", "id": "Q8NB14-1", "name": "Ubiquitin carboxyl-terminal hydrolase 38", "aln": "MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEAS---RPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLSLAFCPSS------------SLENMSVQDPASSPSIQD-------------------------GGLMQASVPGPSEEPVVYNPTTAAFICDSLVN-----------------------EKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKP-----GGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTS--FQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCS-FRPNGFD-----DNDPPGSCGPTGGGGGGGFNTVGRLVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0QWN7-1", "uniprot_id": "M0QWN7_MOUSE", "id": "M0QWN7-1", "name": "ubiquitinyl hydrolase 1", "aln": "MDKILEAVVTSSYPASVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGTEELPRRVGCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGAR---ALACVQLGLQLLPDGPAADEVFALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGAHRLLFCQQLVRCLGRFRCPAEGEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCTEE-EPPSSALASVVQHLPLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFSILIEVSLAKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPAMVASLVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHIPNEDRIKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSVLQALFMASDFRHCVLRLTENNSQPLMTKLQWLFAFLEHSQRPAISPENFLSAS---WTPWFSPGTQQDCSEYLKYLLDRLHEEEKTG----------------MRICQKLKQSSLPSPQEELPSSNATSVEKMFGGKIVTRICCLHCLNVSSREEAFTDLSLAFPPPERSRHRRLGSVMLPTEDVRVQELTLAPRAPG-----AQRQRKRCITGDAPRTGLDSEGVDTIGTGGRSGQE-KVEREQAGKEKEVAED---REEEGTREE-EKEEGEEKDKEKEKKEDEKEKEAENGKEKEGDSLGPGTHREAATPPREQTCGPEGSRSVLDLVNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVTIPLLLRLPLAGGQ--------------------------------------GQAYDLCSVVVHSGVSSESGHYYCYAR------------------EGAARPAPVLG----------STERPEPENQWYLFNDTRVSYSS--FESVSNVTSFFPKDTAYVLFYRQRPRED---PAAEPGSPRVRAEPTLHKDLMEAISKDNVLYLQEQEKEARSRAAYISTLPAPPHWGRGFDEDKDEDEGSPGGCNPAGGNG-----DFHRLVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8S4-1", "uniprot_id": "F1M8S4_RAT", "id": "F1M8S4-1", "name": "ubiquitinyl hydrolase 1", "aln": "MDKILEAVVTSSYPASVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGTDELPRRVGCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGAR---ALACVQLGLQLLPDGPAADEVFALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGAHRLLFCQQLVRCLGRFRCPAEGEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCTEE-EPPSSALASVVQHLPLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFSILIEVSLAKIEKVFSKLLYPIVRGAALCVLKYMLLTFQHSHEAFHLLLPHIPPMVAALVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHIPNEDRIKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSVLQALFMASDFRHCVLRLTENNSQPLMTKLQWLFAFLEHSQRPAISPENFLSAS---WTPWFSPGTQQDCSEYLKYLLDRLHEEEKTG----------------TRICQKLKQSSLPSPQEELPSSNATSVERMFGGKIVTRICCLHCLNVSSREEAFTDLSLAFPPPERSRHRRLGSVMLPTEDVRAQELTLAPRAPG-----AQRQRKHCITGDAPRTGLDIEGVDTVGNGGQSGQE-KVEREQAGKEKEVAED---REEEGPREE-EKEEGEEKDKEK--KEDEKEKEAEDGKEKEGDSLGPGTRKDAATPPREQACGPEGSRSVLDLVNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVTIPLLLRLPLAGGQ--------------------------------------GQAYDLCSVVVHSGVSSESGHYYCYAR------------------EGAARPAPVLG----------STERPEPENQWYLFNDTRVSFSS--FESVSNVTSFFPKDTAYVLFYRQRPQEA---PEAEPGSPRVRAEPTLHKDLMEAISKDNVLYLQEQEKEARSRAAYISTLPAPPHWSRGFDEDKDEDEGSAGGCNPAGGNG-----DFHRLVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2H5-1", "uniprot_id": "UBP35_HUMAN", "id": "Q9P2H5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 35", "aln": "MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRVGCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPR---ALACVQLGLQLLPEGPAADEVFALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRCPAEGEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEE-EPPSSALASVVQHLPLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFSILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVASLVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPLMTKLQWLFGFLEHSQRPAISPENFLSAS---WTPWFSPGTQQDCSEYLKYLLDRLHEEEKTG----------------TRICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVMRPTEDITARELPPPTSAQGPGRVGPRRQRKHCITEDTPPTSLYIEGLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETEKEAE--QEKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGR--------------------------------------GQAYDLCSVVVHSGVSSESGHYYCYAR------------------EGAARPAASLG----------TADRPEPENQWYLFNDTRVSFSS--FESVSNVTSFFPKDTAYVLFYRQRPREG---PEAELGSSRVRTEPTLHKDLMEAISKDNILYLQEQEKEARSRAAYISALPTSPHWGRGFDEDKDEDEGSPGGCNPAGGNGG----DFHRLVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36026-1", "uniprot_id": "UBP11_YEAST", "id": "P36026-1", "name": "Ubiquitin carboxyl-terminal hydrolase 11", "aln": "-----------------------------------------------MLLNPD---------QILNLVRKVYEVDIKQFYSQLRLKNLRG------------LLDHAAHLFNVYLRDLEINQEMEALTAFIIG----------CYYLYLIIPQSLQFQTRN--------NLYSSYAKLKNDYQDEHVMGYVLKVVRDESTVIVDRYLAESNGICRTIKRKRAYS-------------------LPLRPLPVHMASLSIHN-----KFDGSLHEIPNELTKPTNDNSKEDIVRESNQIASSNKLEAGSEVAYYTSKEALSKPSYLKLSTGKDALFKTLSSPATAP--------PVHSLEVSSQIRDSSQDSSSSLSKVEK------------PKEEEGKIEAIESS-APKAYNLPVIE-------DSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLFLNTNKYPKEVQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQEFLLIVLARIHEELSNENVVKYYP---DLVSYDANALQVNPSKYEKWYERNVITDGLSPIDHIYRGQLENILKCQRCGNSSYSYSTFYVLSLAIPKLS------------------------------------------------------------LYSFTSKSRKIKLEDCINLFTGDEELS-----------------------------GDNAWDCPNCRITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSSDDSTKNAK---KRNSKKLTTIKSLDFIVLPPILVIHLSRFYYDLTKKNS----TVITYPLILNIILKNGK--------------------------------------VIRYKLYGTVNHSGNLIN-GHYTSVVN---------------------KEKSHEIG---------------LNRQVWVTFDDDYIQQHRKDRNNFEAGKTEMSSDEVYVLFYERMDEEN------------------YEEEFC-----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:*. : : : .*:. : * * ::: : : * :: * : ::. : . . :* .::: *. :. . . * :: : : *:. : ::. * :**. : : .*: . .: :: .: : :: * .: . :: : :*: :*: :*: . : .:.: : : . .::. : . . * * : :. ..:: * :: : *. * :**::. *. .: : :.. * . . :. .. : .: : : .:::: **::..:* : . * .: ** : . * *. *:. . . * *** .*:* :* *:*** . : . : ::::: *:: . : * * . * .:* ****: . . : . . .* : . . . : * . ::. :.: * : : : :. : * ::: * *:: * ** :* :: **:*.: : * * ..* *** : *** . .. : :* : * *:* : :... .: :..* .***:*.: .::: ", "identical_positions": 88, "similar_positions": 228, "identity": "7.87%" }, { "cls_id": "homologset.agr.SGD:S000001807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06876-1", "uniprot_id": "MYB_MOUSE", "id": "P06876-1", "name": "Transcriptional activator Myb", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRPRHSIYSSDEDDEDIEMCDH---------------------------------DYDGLLPKSGKRHLGKTR--------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--------------------------------------------------------RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEEEDRIIYQAHKRLGN-RWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVATSFQKNNHLMGFG-------------------------------------------------------------------------HASPPSQLSPSGQSSVNSEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYN---------------------DEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHG------------------------------DSAPVSCLGEHHATPSLPADPGSLPEES-ASPARCMIVHQGTILDNVKNLLEFAETLQFIDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLNTSSNHESSGLDAPTLPSTPLIGHKL---TPCR-DQTVKTQKENSIFRTPAIKRSILESSPR---------------------------------TPTPFKHALAAQEIKYGPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQESGP--------------------PLLKKIKQEVESPTEKSGNFFCSNHWAENS--------------------------LSTQLFSQASPV-----ADAPNILTSSVLMTPVSEDEDN-----------------------------------------------------------------------------------------------------------------------------------------------------VLKAFTVPKNR-----------PLVGPLQPCSGAWEP------------------------------------------------ASCGKTEDQMTASGPARKYVNAFSARTLVM----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2A4-1", "uniprot_id": "A0A0G2K2A4_RAT", "id": "A0A0G2K2A4-1", "name": "Transcriptional activator Myb", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRPRHSIYSSDEDDEDIEMCDH---------------------------------DYDGLLPKSGKRHLGKTR--------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--------------------------------------------------------RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEDEDRIIYQAHKRLGN-RWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVVSSFQKNNHLMGFA-------------------------------------------------------------------------HASPP----PTSQSSVNGEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYN---------------------DEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHG------------------------------DSAPVSCLGENHATPSLPADPGSLPEES-ASPARCMIVHQGTILDNVKNLLEFAETLQFIDSD----SSRCDLSSFEFSEEAAAFSPSQ-------------QHTGKTFQLQEREGHGTRSAGEPSLRVTRRVLSEASLRQAKASPLVFLRKRRGQASPTAAGDSSSSLFADVSS----------------------------------------STPKRSPVKSLPFSPSQFLNTSSNHENSGLDTPTLPSTPLIGHKL---TPCHRDQTVKTQKENSIFRTPAIKRSILESSPR---------------------------------TPTPFKHALAAQEIKYGPLKMLPQTPSHVVEDLQDVIKQESDESGIVAEFHENGP--------------------PLLKKIKQEVDSPTEKAGNFFCSNHWEETN--------------------------LSTQLFAQASPV-----ADAPNILTSSVLMTPVSEDEDN-----------------------------------------------------------------------------------------------------------------------------------------------------VLKAFTVPKNR-----------PLVGPLQPCVGAWEPT-----------------------------------------------PSCGKTEDQMTASGQARKYVNTFSARTLVM----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10242-1", "uniprot_id": "MYB_HUMAN", "id": "P10242-1", "name": "Transcriptional activator Myb", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRPRHSIYSSDEDDEDFEMCDH---------------------------------DYDGLLPKSGKRHLGKTR--------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--------------------------------------------------------RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEEEDRIIYQAHKRLGN-RWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFA-------------------------------------------------------------------------QAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYN---------------------DEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHG------------------------------DSAPVSCLGEHHSTPSLPADPGSLPEES-ASPARCMIVHQGTILDNVKNLLEFAETLQFIDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPR---------------------------------TPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENGP--------------------PLLKKIKQEVESPTDKSGNFFCSHHWEGDS--------------------------LNTQLFTQTSPV-----ADAPNILTSSVLMAPASEDEDN-----------------------------------------------------------------------------------------------------------------------------------------------------VLKAFTVPKNR-----------SLASPLQPCSSTWEP------------------------------------------------ASCGKMEEQMTSSSQARKYVNAFSARTLVM----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51960-1", "uniprot_id": "MYBA_MOUSE", "id": "P51960-1", "name": "Myb-related protein A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKR-----SRSEDEDDDLQYADH---------------------------------DYEVPQQKGLKKLWNRVK--------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--------------------------------------------------------RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGN-RWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK----------------------------------------------------------------------------------------PCATMDHLQTQNQFYIP--VQIPGYQYVSPDGNCVEHVQ----TSAFIQQPFV---------------------DEDPDKEKKIKELELLLMSAENEVR-RKRLPPQ--PGSFSSWSGSFLMDDSMSN----------------------------------TLNNLEEHTTEFYSMDENQTVSAQQ-NSPTKFLAVEANAVLSSLQTIPEFPRTLELIES---DPVAWSDVTSFDLSDAAASPVKSTPVKLMR----IQHNEGAMECQFNVSLVLEGKKNSRNGGDSEAIPLTSPNVVKFSTPPTISRKKKRIRVGQSAGSELGSASLSEVGN----------------------------------------RRIKHTPVKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPR---------------------------------TPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDIFLKEEDE----------------------PAYKSCKQEHSASVKKVRKSLALESWDKEE--------------------------PGTQLLTEDISD-----MQSENILTTSLLMIPLLEIHDNRCNLT----------------------------------------------------------------------------------------------------------------------------------------PEKQDINSANKTYTLNKKRPNPNPC---KAVKLEKSLQSNCEWET------------------------------------------------VVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARW4-1", "uniprot_id": "A0A8I6ARW4_RAT", "id": "A0A8I6ARW4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKR-----SRSEDEDDDLQYADH---------------------------------DYEVPQQKGLKKLWNRVK--------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--------------------------------------------------------RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGN-RWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK----------------------------------------------------------------------------------------PCATMDHLQTQNQFYIP--VQIPGYQYVSPDGNCVEHVQ----TSAFIQQPFV---------------------DEDPDKEKKIKELELLLMSAENEVR-RKRLPPQ--PGSFSSWSGSFLMDDSMSN----------------------------------TLNNLEEHTTEFYSMDENQTVSAQQ-NSPTKFLAVEANAVLSSLQTIPEFAETLELIES---DPVAWSDVTSFDLSDAAASPVKSTPVKLMR----IQHNEGAMECQFNVSLVLEGKKNSCNGGDSEAIPLASPNVVKFSTPPTILRKKKRLRVGQSAGSELGEGSLSEGNN----------------------------------------AALKHTPVKTLPFSPSQFFNTCPGSEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPR---------------------------------TPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDIFLKEEDE----------------------PAYKSCKQEHSASVKKVRKSLALESWDKEE--------------------------PGTQLLTEDISD-----MQSENILTTSLLMIPLLEIHDNRCNLT----------------------------------------------------------------------------------------------------------------------------------------PEKQDINSANKTYTLTKKRPNPNTC---KAVKLEKSLQSNCEWET------------------------------------------------VVYGKTEDQLIMTEQARRYLSTYTAPSSTSRALIL-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10243-1", "uniprot_id": "MYBA_HUMAN", "id": "P10243-1", "name": "Myb-related protein A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKR-----SRSEDEDDDLQYADH---------------------------------DYEVPQQKGLKKLWNRVK--------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--------------------------------------------------------RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGN-RWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK----------------------------------------------------------------------------------------PCAAMDHMQTQNQFYIP--VQIPGYQYVSPEGNCIEHVQP---TSAFIQQPFI---------------------DEDPDKEKKIKELEMLLMSAENEVR-RKRIPSQ--PGSFSSWSGSFLMDDNMSN----------------------------------TLNSLDEHTSEFYSMDENQPVSAQQ-NSPTKFLAVEANAVLSSLQTIPEFAETLELIES---DPVAWSDVTSFDISDAAASPIKSTPVKLMR----IQHNEGAMECQFNVSLVLEGKKNTCNGGNSEAVPLTSPNIAKFSTPPAILRKKRKMRVGHSPGSELRDGSLNDGGN----------------------------------------MALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPR---------------------------------TPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDLFLKEEDE----------------------PAYKSCKQENTASGKKVRKSLVLDNWEKEE--------------------------SGTQLLTEDISD-----MQSENRFTTSLLMIPLLEIHDNRCNLI----------------------------------------------------------------------------------------------------------------------------------------PEKQDINSTNKTYTLTKKKPNPNTS---KVVKLEKNLQSNCEWET------------------------------------------------VVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9R3-1", "uniprot_id": "A0A8M2B9R3_DANRE", "id": "A0A8M2B9R3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANMK----SRSEDEDEDRHSTDP---------------------------------DSREP--KNSKRTLCKIK--------WSRDEDEKLKKLVEQQGTDNWKLIANYFPT--------------------------------------------------------RTDGQCQHRWQKVLNPELVKGPWTKEEDQRVIELVHKYGPKRWSVIAKHLQGRIGKQCRERWHNHLNPEVKK--SSWTQEEDRIIYEAHKRLGN-RWAEISKLLPGRTDNSIKNHWNSTMRRKVEHEGYLQEGNKSYNSDPGQKKRPK----------------------------------------------------------------------------------------SSPTVEYPHDQNQPILSGQSQPPRYPYRSQSAQCLENINV---RISSFVSPFH---------------------D-DPDKEKRIKELELLLMSAESEVR-RQSGPRN--PESYSSWSDSLPDDS---------------------------------------VESVEDR-----GVEDGRSVSIPLPVSPSKFLAAEASAVLSTLETIPEFAETMELIDSVSRDPLAWSDVTSFDLSESGPSPKPTNPADVC---------TETLAFPINAPTVQTMTRPCAAVSQGKSGTLPNTCMNRFSSPPTSICRKKRREGGDQSPAEERSCSYIDNSG----------------------------------------NSPKHTPVKGLPFSPSQFFNVS-GGEPLSLDNPALTSTPVCGQKCLLNTPHQKETTPKHQKENAGFRTPKLHKNIVVHTPR---------------------------------TPTPFKNALAAQEKMHGPLRMVPQPLALLEEDIREVLKEETG-ADIFTQVQNQ----------------------LQYRSYEQ-MEAPARKVRKSLVLDSWEKDC--------------------------LNVQLFPQQQINNNGTTSQSDGLLTRSMLMMPLTEREENSCSPE----------------------------------------------------------------------------------------------------------------------------------------SLKDSLSVVCSVSPQGKRENMIQ-----RSPLYQTPTPANNEWDA------------------------------------------------VVFGKTEDQLIMTEQARRYLNP-NPTACISRALVL-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48972-1", "uniprot_id": "MYBB_MOUSE", "id": "P48972-1", "name": "Myb-related protein B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRR------TRCEDLDELHYQDV---------------------------------DSDLLEQRDN---RCKVK--------WTHEEDEQLRALVRQFGQQDWKFLASHFPN--------------------------------------------------------RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGN-RWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPAESRDCKP-VYLLLELED---------------------------------------------------------------------------------------------KEQHQGVQPVDGQGSLVSSWPLVPSIVKEESSEEEIAIAATSAKELGH---------------------EPVPADLGEVRTPEPPESL-KREYQ-EFSSPETSLPYKWVVEAANLLIPAVGSS---------------------------------------------LSEALDLIESDPDAWCDLSKFDLPEEPSTEGSVVSSPVQPQTSQQQQ-----------EEALQSSQQAATPGPSV-----------------TEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNS---------------------------------------LTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSSEVLPDQK-YSMDNTPH---------------------------------TPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGMELIIEDDMRP----------------------EKQKRKPGLRRSPIKKVRKSLALDIMDEDG-----------------------------KLMSSTMPK---PLSLPTSVTPSSCGFTSPGSKEGNS---------------------------------------------------------------------------------------------------------------------------------------------------LLNQGFLQAKPEKVVAAQ--KTRSHIPTPAPMTHAWKT------------------------------------------------VACGGTKDQLFMQEKARQLLSRLKSSHTSRTLILS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKK8-1", "uniprot_id": "A0ABK0LKK8_RAT", "id": "A0ABK0LKK8-1", "name": "Myb-related protein B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVVPVFERLRQENCQPELWRPCFKKK------KVGEELDELRYQDT---------------------------------DSDLLEQRDN---KCKVK--------WTHEEDELLRALVRQFGQQDWKFLASHFPN--------------------------------------------------------RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGN-RWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPNESRDCKP-VYLLLELED---------------------------------------------------------------------------------------------KDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQ---------------------EPVPTDLGEVRTPEPLEFL-KREYQ-EESSPETSLPYKWVVEAANLLIPAVESS---------------------------------------------LSEALDLIESDPDAWCDLSKFDLPEEPSAEGSVNSSPVQLQTPQQQQQ----------HQQALSFHQAATPGPSV-----------------TEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNS---------------------------------------LTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYP-SFVTPDQK-YSMDNTPH---------------------------------TPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGIELIIEDDMRP----------------------EKQKRKPGLRRSPIKKVRKSLALDIVDEDG-----------------------------KMMSSTSPK---TLSLPTSVPSSSSGFILPGIKEDNS---------------------------------------------------------------------------------------------------------------------------------------------------LLNQGFLQAKPEKVVATQ--KPRSHIPAPAPMTRAWKT------------------------------------------------VACGGTKDQLFMQEKARQLLGRLKSSHTSRTLILS-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10244-1", "uniprot_id": "MYBB_HUMAN", "id": "P10244-1", "name": "Myb-related protein B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRR------TRCEDLDELHYQDT---------------------------------DSDVPEQRDS---KCKVK--------WTHEEDEQLRALVRQFGQQDWKFLASHFPN--------------------------------------------------------RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGN-RWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPPVYLLLELED---------------------------------------------------------------------------------------------KDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQ-----------------------EPIGTDLDAVRTPEPLEEFPKREDQ-EGSPPETSLPYKWVVEAANLLIPAVGSS---------------------------------------------LSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQ--------------VLPPRQPSALVPSV-----------------TEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNS---------------------------------------LTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHA-AFVTPDQK-YSMDNTPH---------------------------------TPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGIELIIEDDIRP----------------------EKQKRKPGLRRSPIKKVRKSLALDIVDEDV-----------------------------KLMMSTLPK---SLSLPTTAPSNSSSLTLSGIKEDNS---------------------------------------------------------------------------------------------------------------------------------------------------LLNQGFLQAKPEKAAVAQ--KPRSHFTTPAPMSSAWKT------------------------------------------------VACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ83-1", "uniprot_id": "A0AB32TZ83_DANRE", "id": "A0AB32TZ83-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSWW------ARGEDEEEALCQDT---------------------------------DSDVADQRDCG--KVKVK--------WTQEEDDKLRKLVLNVGSNDWKYIAGFLPN--------------------------------------------------------RSEHQCQHRWFKVLDPDLVKGPWTKEEDEKVIELVKKYGNKQWAMVAKHLKGRLGKQCRERWHNHLNPDVKK--SSWTPDEDLIIYKAHRVLGN-RWAEIAKLLPGRTDNAVKNHWNSTIKRKVETGFYSG----VDTTLHVLQQTDP---------------------------------------------------------------------------------------------EELLSEEVEISCDG--------ASEELPVECSKREPEEKATAPPQK-----------------------------ASSPKTP-------KASTS-PKSEGGDSNVSTWVMDSSGFLSPSAAPT---------------------------------------------LKEVMELMDGDLEGWCTMSDFDLPEES-------------QSSELLQ-----------------------------------------------FRLEGSALQELSKGSKGELIPISP----GG---ATPPSILSRRSRRRIALSP-----------DPNDS---------------------------------------MTPKSTPVKILPFSPSQFLNMWTKQDTLDLENPSLTSTPVCSQKAVVTTPLHRDKTPLTQKENSLFITPNHK-SDLDTMPR---------------------------------TPTPFKNAMEK----YGPLRPLPPTP-NLEEDLKEVLRSEAGIELIVEDEAPA----------------------EKKRKQ--VYRPPMKKVRKSLALDVIDCSES------------------------VAARKQQIKATVK---PSQKPQTVQPEPP-VSSCAVKEEN----------------------------------------------------------------------------------------------------------------------------------------------------VLDQGFILGPNESGPASKPVLATPKTISPLPMSAAWET------------------------------------------------VVCGRTKDQLFMTEKARRYLRSLKSHTPNRALILS-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BP86-1", "uniprot_id": "SNPC4_MOUSE", "id": "Q8BP86-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSEADSLPDEDLET------------------------AGAPILEEEGSSESSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEKQSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARSAEEIRKFWQSSEHPSISKQE--------WSTEEVERLKAIAATHGHLEWHLVAEELGTSRSAFQCLQKFQ-QYNKTLKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKK--GRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRKRGQRPRHSSQWSSSGSSSSSS-------------------------------------------------------------------------------EDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQYRVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCT---QDASQNHHKEGSTTVSAA--EKNQLQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKS-----------------------------------HTLMKERPKQPLLPSSRSGSDPGNNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRPATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGTRNTQPHLLQASSNAKNNTGCLPS-MTGEQTAKR---------------------------------------ASHKGRPRLGSCRTEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALG-LNSQLLVSSPVILQPPLLPVPHGSPVVGPATSSVELSVP---------------VAPVMVSSSPSGSWPVGGISATDKQPPNLQTISLNPPHKGTQVAAPAAFRSLALAPGQVPTGGHL--STLG--QTSTTSQKQSLPKVLPILRAAPSLTQLSVQ---------PPVSGQPLATKSSLPVNWVLTTQKLLSVQVPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAFLE----------QPPASTDTEPK------------------------------------------------------------------------------GPQGQEIP----------------------------PTPGPEKAALDLSLLSQESEAAIVTWLKGCQGAFVPPLGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLELVQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLG-DLELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDLNVLRTRRARHSRR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LYZ6-1", "uniprot_id": "F1LYZ6_RAT", "id": "F1LYZ6-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKVTQEIQELERILYPGSSSVHFEVSESSLSSDSEADPLPDEDLET------------------------AGAPVLEEERSSEGSNDDEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLAGTKCPKVKDAKSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKAAQGIKAFEQLLVTKWKHWEKDLLRKSVVSDRLQRLLQPKLLKLEYLQEKQSRVSSELEKQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNVNFEGARSAEEIRKFWQSSEHPSINKKE--------WSTEEVERLKTIAASHGHLEWHLVAEELGTSRSAFQCLQKFQ-QYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRRIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKK--GRWDAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQKRRGQRSRHSSQWSSCSSSSSSSSSSSG-------------------------------------------------------------------------SEDYGGGS-SSSSNSSEDSEVELEEPLQNSRALAPQQYSVPDIDLWVPTRLIDSRSQREETGCYPVHPAVSCR-------TQNHHKEGSTVVSAP--ERNQMQECCETHSTVPRGVQSLHSSDTHGASVKEPACKS-----------------------------------HTLVKERRRQPPLPNSRSGSDPGNSMAGPHLRRLWHGTFQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAVQRPAAVQTQADSIRMQLECARLASTPVFTLFIQLLQIDTAGCMEVVQERKTQPPALLQPGTRNTQPHLLQASSNAKNNTGCLLPGMLDEQTAKR---------------------------------------TSQKGRPRLGSCKAEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALTALSSQLLVSSPVLLQPPLLPAARGSPVVGPAASSVELSVP---------------VAPVMVSSSPSGSWQVGGISATDKQPPNLQTIPLNPSHKGTQIAAPAAFRSLALASGHVSTGCPL--NTLG--QTSTTSQKQSLPKVLPILPAAPSLTQLSVQPLSLPPVLNPPASGQPPATKSSLPVSWVLTTQKLLSVQVPAVVGLPQPVTTPETIGLQAKQLPSPSKTPAFLG----------QPPASTDTEPK------------------------------------------------------------------------------GPQGQQTP----------------------------PTPGPEKKALDLSLLSQESEAAILTWLTGSQGACVPPLGSRMSYHPPSLCSLRALSSLLLHKKDLEQKASSLVAGQAAGAQPEPKAGALQASLELVQRQFQNNPAYLLLKTRFLAIFSLPAFLATLPPNSVPTTLSPAMAVGSESDSEDFG-DLEPRDGATQLDCMACRVRANLMAPDPVVSHLPSWERRAPSPSAVSAPSHLDASDDLDDLDVLRTRHARHSRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SXM2-1", "uniprot_id": "SNPC4_HUMAN", "id": "Q5SXM2-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDVDAEREKITQEIKELERILDPGSSGSHVEISESSLESDSEADSLPSEDLDP------------------------ADPPISEEERWGEASNDEDDPKDKTLPEDPETCLQLNMVYQEVIQEKLAEANLLLAQNREQQEELMRDLAGSKGTKVKDGKSLPPSTYMGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVSDRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQE--------WSREEEERLQAIAAAHGHLEWQKIAEELGTSRSAFQCLQKFQ-QHNKALKRKEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKK--GRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKKQGLRRRR-RRARHSVRWSSTSSSGSSS--------------------------------------------------------------------------------GSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAASLSPPKGSSASQGGSKEASTTAAAPGEETSPVQVPARAHGPVPRSAQASHSADTRPAGAEKQALEGGRRLLT------------VPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASQRPAVVQTQADGLREQLQQARLASTPVFTLFTQLFHIDTAGCLEVVRERKALPPRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKS---------------------------------------ASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGP---------------GAPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPE--SGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLS-----LTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLLHKKALEHKATSLVVGGEA----ERPAGALQASLGLVRGQLQDNPAYLLLRARFLAAFTLPALLATLAPQGVRTTLSVPSRVGSESEDEDLLSELELADRDGQPGCTTA----------------TCPIQGAPDSGKCSASSCLDTSNDPDDLDVLRTRHARHTRKRRRLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04197-1", "uniprot_id": "MYB_DROME", "id": "P04197-1", "name": "Myb protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSK-------------------------------TTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHFKD--------------------------------------------------------RLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKK--TAWTEKEDEIIYQAHLELGN-QWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRS-----------------------------------------------------------------------------------------------------------------VNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSE---------------------NADGASVTAVKGGDLAQESQDDHQK----------GSNLAHLSMQHLIKLTMPR--------------------------------------------QTPIILKRTRKHIPETHHQAGCSSSETFNQEEAAGNARSRPPSSPVISP----------------------------------------------------------------------------------------------------------------------------------------------------------------IKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGP---------R------------------------------------TPTPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMG---------------AADQNSTLSTEYNAQSPPHMKRARKSLLSTWSSNH-----------------------------PYNAGSAKR----IQPFETETPSKFLTSPGDILKDTLCSEQ-----------------------------------------------------------------------------------------------------------------------------------------------DLPFDEGRKENRPFHNRRINKYRGGLTYDHVIDPKWAR------------------------------------------------VACGKSRDQMFMEEQAYACLKNLSCISRSLNFEKQKCLVNSFDRFGSL----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3ASS0-1", "uniprot_id": "A0A8M3ASS0_DANRE", "id": "A0A8M3ASS0-1", "name": "", "aln": "MTHLSRDSWLYTHDVQVTYNSFIKVSPCPKMASDDLRAQRDKIQREILALESTLGADSSIADQLSSDNSSDYESDDSGPTVKRVERDDLETERLRIQREIEELENALGADAALENVLQDSDHDTDSSEDSADDLELPQNVETCLQMNLVYQEVLKEKLAELEQLLIENQQQQKEIEVQLSGPGNSIFSVPGVPPQKQFLGYFLKPYFKDKLTGLGPPANEETKERMKHGSIPVDNLKIKRWEGWQKTLLTNAVARDTMKRMLQPKLSKMEYLSNKLCRAEGEEKEQ-LKAQIELIEKQIAEIRTLKDDQLLGDLQDDHDWDKISNIDFEGLRQADDLKRFWQNFLHPSINKSV--------WKQDEIYKLQAVAEEFKMCHWDKIAEALGTNRTAFMCFQTYQRYISKTFRRTHWTEEEDDLLRELVEKMRIGNFIPYIQMSHFMVGRDGSQLAYRWTSVLDPSLKKGPWSKEEDQLLRNAVAKYGTREWGRIRTEVPGRTDSACRDRYLDCLRETVKK--GTWSYAEMELLKEKVAKYGVGKWAKIASEIPNRVDAQCLHKWKLMTRSKKPLKRPLSSITTSYPRNKRQKLLKTVKEEMFFNSSSDDESQINYMNSDESDDLAEDENLEIPQKEYVQTEMKEWIPRNAMVWTITPGSFRTLWVRLPTNEEELRESTKESGLGSDSSENSACPNDEPIMERNTILDRFGDVERTYVGMNTVVLHRRTDDEKAMFKVCMSDVKQFIQMKATEFAVKKKKKIKNKKRTLRDVFSLNTDLQKAVIPWIGNVIISIPANEAIFCEGDVVGIKAASIRLQKTSVFTFFIKAFHVDVNGCRTVIEIHKKLDIKMPLAINGNPKPTPISTSPKTVAVLLQQSKAASEHKKPAEPSQQPSLPPSQKPSLPPSVPPSQQPTLPPPSQLSQPPPQPPSLPPSQPPAQQPSLPPPQPPSLPPPLPPPQPPSLPTSQQQSLPPSQQPSLPPSQQHSLPPFQNPSLPPSQQPSLPPSKQPPQPLPVRQITTPTLIYPNNLVITNPNMEGEVQHLVFKGLLLPQQPSKAVSHIPLPVMQPKTPAQPIVVSKSPSVQDSNSVKSSKRICKPTKKAQALMEQSKVKSRKKEPQKQNQGNKNVVFPTVTLQTSPVIKILSPARLVQVTGLSPNFSSNQTINMPDKSLTIKSPQPCSSGNLHQSAPVVVHSSTNPTFVHSSVSNVSRDNLNVSSTINISPRVSRDALNPTSFLNSTTFPLPQNLSVQQSVQIVPQIPINVVHKATCTKAAKTSSD----------SSSDESVVKQHQSSPSTGRSIPPAVFNIQPNPSTPPTLSSGPVIFNPNNKVVAPKLCGLNVSSSQLPTVSTQKTKYRPIRPLG---------------------------------------------------------------------------------PLPVVAPPSRKVTSMSRIRAQSEGEPLISLRELPAAGVNFDSHLIFPEKSSEVDDWMDGKGGIPLPHLDTSLPYLPPSAATIKTMTDLLRAKQPLLLAAKKVLPAQYQDECN--EEVEVEAIRKVVAERFASNPAYLLCKARFLSCFTLPALLATINPCEERQLLSEDDEEDDHLATINPSEERQSSTEDDEED--------------------LQTNERSQPPTARTELNMNENEASAKQFSGIGPKRQRNQRIKRLIK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22035-1", "uniprot_id": "BAS1_YEAST", "id": "P22035-1", "name": "Myb-like DNA-binding protein BAS1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNISTKDIRKSKPKRGSGFDLLEVTESLGYQTHRKNGRNSWSKDD-------------------------------DNMLRSLVNESAKELGYEN---------GLEDVKTIQQSNHLSKCIAWDVLATRFKHT------------------------------------------------------VRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVLGPGSKGRLREWTLEEDLNLISKVKAYGT-KWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLR-------------------------------------------------------------------------------------QHPIADSDIRSDSTPNKEEQLQLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILN----------------DSKPQALPPLKEISAPPPIRMTQVGQTHTSGSIRSKVSLPIEGLSQMNKQSPGG---------------------------------------ISDSPQTSLPPAFNPASLDEHMMNSNSISDSPKHAYSTVKTREPNSSSTQWKFTLKDGQGLSISNGTIDSTKLVKELVDQAKKYSLK---------ISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNPEYRTSLDN----------------------------------------MDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQANTLIPTNSTATNNEIIQGNVSANSMSPNFNG---------------------------------TNGKAPSSTASYTTSGSEMPPDVGPNRIAHFNYLPPTIRPHLGSSDATRGADLNKLLN----------------PSPNSVRSNGSKTKKKEKRKSESSQHHSSSS-------------------------VTTNKFNHIDQSEISRTTSRSDTPLRDEDGLDFWETLRSLATTNP---------------------------------------------------------------------------------------------------------------------------------------------NPPVEKSAENDGAKPQVVHQGIGSHTEDSSLGSHSGGYDFFN----------------------------------------------ELLDKKADTLHNEAKKTSEHDMTSGGSTDNGSVLPLNPS-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :: * :. : * : ** *:* * :* *: :** : : :.* * : : ** * .*: * * * * : . * :* .*:. : * . :*. . . : . . ", "identical_positions": 26, "similar_positions": 36, "identity": "1.52%" }, { "cls_id": "homologset.agr.SGD:S000001811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4P9-1", "uniprot_id": "MRP7_MOUSE", "id": "Q8R4P9-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPRTTNHSPALNPG--WRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHS-PHGRSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQE-------PWTHDPFLSS--ESQETEVAEDGESWLSR---------------FSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQ-----------------------------------------LWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLEE-GQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALK---------------------------LGP---SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMG-HQLTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDP---------------IGASQKTFISH---LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVS-------------ELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILG-VLSHTTRLLCTHRTEYLER-ADVVLLMEAGQLVRTGPPSEILPLVQAVPTAWAEKEQVATSGQSPSVCDLERTTEEELEVEQSTCGCLVQ------EESKSEGAVALHVYRAYWRAMG-SGLAAAILVSLLLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMGGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX04-1", "uniprot_id": "D3ZX04_RAT", "id": "D3ZX04-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAVLSACHLGTPRTNNIIQPFNPG--WRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHS-PHGHSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPRE-------PWTHDPFLSP--ESQEREVAEDGESWLSR---------------FSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQ-----------------------------------------LWRALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLEE-GQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLK---------------------------LGP---SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACVYLWAALPVVICIVIFITYVLLG-HQLTATKVFTALALVHMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDP---------------TGTSQKTFISH---LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVS-------------DLSKGFGLATQEPWIQCATIRDNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKTLYLLDDPLAAVDADVANHLLHRCILG-VLGHTTRLLCTHRTEYLER-ADLVLLMEAGRLVRAGPPSEILPLVQAAPTALADKEQVTDSGQSPSVHNLEKTT-EELDVAQNTSGRLVQ------EESKSEGAVALHVYRAYWRAMG-SGLATAILISLLLMQATRNGADWWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGN----LLSIPLHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDIPQEPHGQPPQSPHQR-VSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLSEVAMAIGGLDGELGERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T3U5-1", "uniprot_id": "MRP7_HUMAN", "id": "Q5T3U5-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MERLLAQLCGSSAAWPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACYLGTPRSPDYILPCSPG--WRLRLAASFLLSVFPLLDLLPVALPPGAGPGPIGLEVLAGCVAAVAWISHSLALWVLAHS-PHGHSRGPLALALVALLPAPALVLTVLWHCQRGTLLPPLLPGPMARLCLLILQLAALLAYALGWAAPGGPRE-------PWAQEPLLP---EDQEPEVAEDGESWLSR---------------FSYAWLAPLLARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGAR-----------------------------------------LWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEE-GQEPLSHGLLYALGLAGGAVLGAVLQNQYGYEVYKVTLQARGAVLNILYCKALQ---------------------------LGP---SRPPTGEALNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFCGWEQALGARVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMG-HQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQLFLDLPNHNPQAYYSPDPPAEPSTVLELHGALFSWDP---------------VGTSLETFISH---LEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVR-------------GLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILG-MLSYTTRLLCTHRTEYLER-ADAVLLMEAGRLIRAGPPSEILPLVQAVPKAWAENGQESDSATAQSVQNPEKTK-EGLEEEQSTSGRLLQ------EESKKEGAVALHVYQAYWKAVG-QGLALAILFSLLLMQATRNAADWWLSHWISQLKAE-NSSQEAQPSTSPASMGLFSPQLLLFSPGNLY--IPVFPLPKAAPNGSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNATPTGRILNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLPPLSIMYYHVQRHYRASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQP----LQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLSEVITSMGGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLV8-1", "uniprot_id": "A0A8M9QLV8_DANRE", "id": "A0A8M9QLV8-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "MGGDIGAAEFISELCHTDVDSPFPVWQNGTISPCANQLLLGSLPHAVFAVISACYISVPRLIHIVSSLPIG--WSLRAASTLLVFLLFIGDLVLVFELQAP---DIYLDTLADGCGILAFLVHFGAILSLQKS-IYRRTRGPALLPVALILSIPNLAFNLTAYTQEIIHHGVSQPLQVIRLAFTVTRGALVLVYLLGYIFPCYRTQRDLLSCNAEDEAPLIVTFEPFEEVTVAEDGSSLLSR---------------LLYLWLNPLLNRGKRGELERPSDVFELPSRLRTKSVTRRFYQCWEKCLQSRALKRPERPDRRPRGNLQDNSWSEAQPERICEGEAEHEVKLLQVLHKAFGLRYYLLGGLKLVASMLAFAGPLLLGGLVGFMET-EGAPLSKGVWCTVGLFASTFLAALLKNIFVYEVSKVALEARAAVISTIYSKALK---------------------------VNAPSLARFNMGEVVNFMSTDTDRVVNFFNSFHEVWSLPFQFVLALYLLYLQVGVAFLGGVGVAVLLVPLNKVLASRILENNKHMLQHKDGRVKLMTEILFGIRVLKYYNWEEHFTQKIEEARKKELHHLKLLKYLDAVCVYTWAALPVVISILTFITYVLLG-NNLTAAKVFSTLALVGMLILPLNAFPWVLNGTLEAKVSLDRIQRFLAVQDQDLSVYYSQVCPEDPPSAVQMVQASFSWKQSEEADSVSIPDDITEEGSPPHSFYLHALNLNVKRGSLVVVVGKVGCGKSSLLAAITGELTRCGGEVFVQ-------------GREQGFGLAVQEPWIQHATVQDNILFGRDYDNMFYQSVIQACALADDLNILPGGDQTEVGENGVTLSGGQKSRLALARAVYMDKEIYLLDDPLAAVDADVAHHLMEKCILG-ILKDKTRILCTHRIEFVDK-ADVVVLMDNGMIVKTGTPSAVLSLVKGP-------KDSKNSSNAKEKDSAGSEEMEASEPELKAELEMFG------EEQKQMGTLSWAVYRSYWKAVG-GCMAVAVLLALFLMQASKNVSDWWLSHWISHMKDN-MTELVSVSATPLLMLSFLSPGRLVFNASARG--------SESSGNMSSELKFYMTVYGSLAAANTVFTAARAFLFAYGAICAATVIHKRLLSSVLKATMTFFDTTPLGRILNRFSSDIYSVDDSLPFVLNILLANVFGLLGMLIVMSYGLPWVLLPLVPLGALYYQTQCFYRYSSRELKRLCSLTLSPVYSHFSETLSGLSTVRASGHTTRFEEENERRLEQNQRCLFNSNAAMQWLDIRLQMIAVTVVTGISVIAVIQHQLKSIDPGLVGLSLSYALSITNLLSGLIFSYAQTEMQLVSIERTEEYSTSIPQEPQQAS----LEVSDRWPERARVEFVDVVLSYRPGLPNALDGVSVEVLPGEKIGIVGRTGSGKSSLFLALFRMVELNQGQILLDGVDISSVRLSDLRSKLAIIPQDPFLFSSSVRENLDPHGRHPDYRLLEALEQCHLGNVVQRNGGLDSEVGERGKSLSVGQRQLLCLARALLTEANILCIDEATASVDQKTDMLLQKTIREKFKDKTVLTIAHRLNTIMDSDKVLVMHAGKVVEFDSPATLCQREDSAFQKLLRGGEDQV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CE68-1", "uniprot_id": "NFT1_YEAST", "id": "P0CE68-1", "name": "ABC transporter NFT1", "aln": "------MIKNGTCPYWERDDLSECARREYIEFKFPLFILLTGMIYAFCKVFRAFYLRGKNHTNEAPEFEEQGNGNHEYARFSVLRLKSAWESRSFCNVNNRSTFDKFKKFIEGAFIVLQLTIHLYILSSMPMDNKKFFHQGFLVQMFLWILLLVVITLRLISASQSFRWVLACKRDLWAVSFYSYASLFTLSILPLRSVFIGKIKDKIMVKYIISETFIDLALLLLLSTSSIEGTRYSFLVENENKKLPPAPTVFGLLTFSRIDRLIWKAYKHCLGN-ADIWDLDINNKSIAILANFEMSSKKGRL------------------------------------------LPNIICYFKAVFISQLFLAFVSSFLNFVPSLLMPRILSYVNDPKSKSWNLVSLYVSSMLVSKIIATTCRGQGLFLGEKGTMQLRTVLISNIYSKTLRRTILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKDNSVNNVMSIDAFKVSEAMNTFYLACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWCATFYGNYQADQLILTDKRTSGISEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATIFFLNHLIWFFGPTLVSAITFSVFIKFQNQTLTPTIAFTALSLFAILRTPMDQIASTVSLLIQSFISLERIQDYLNESETRKYEILEQ-----SNTKFGFEDASMEWEA------------------AETSFKLKNISIDFKLNSLNAIIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPWLISGTIKDNVVFGEIFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQRIALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVTKRADWLVILDRGEVKSQGKPSDLIKSNEFLRESINNDSKNTTHNQIDLKRSTTSKKTKNGDPEGGNSQDEVCAEVENFEETKMEGSVKFSAYKWLADYFGGLGVVFVFTSSSILIHGITLSQGFWLRYWLDTGSSGSKSTWLYRIVEG------------------------------------HSNIYFLLTYIIIGLVSSFLTSGKVWIAIISGTNVTKKIFAKLLSSILYAKLRFHNVTPTGRIMNRFSKDMDIIDQQLIPNFEGLSYSVVVCLWIILLIGYVTPQFLLFAIPLCALYYTVCTLYLRASRELKRIDNINISPIHQLFAEAIKGVTTIRALADERRFITQSLVAIDRSNAPFFYLNMATEWITYRVDIIGTLVLFSSSVMIIMKAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ::* : :*. *: * :: . . . : :: : : . . : . : * : : . :* . :* :.: : * : * : : . : * * . : : : *: :. * . * * . :. : * :: : * : * :*.::* * .**: ::.::: . . . .: . .:.: :. : * ::: * .::. :* *:*: . : ... *.:. *: :: : .:*: . : . :* :** :* : ..* : ::*:* *: : . * .* *.. ::* * .***:* **: : :: * *: *: : * *.::. * .:: : : **.: .*::*:*. :* *:: :. .:. ::: :**:*** :* . . . : . : * :.*. . :* : ::.* . * ::* .*.****** .: *** * : * :.:. . * **: .*::**::**. :: : .*:::*.* .*:. :..* :*:**: *.:*****: *:*****:* .. :*** *:***.:.* :: ..*: * :: * :: :*. . : : ** ::::: * : * ** :: : . . : : . ** * *:: .*: .* :. .. : :*::. .:** :*:. . . ::: .* :. ..:. * :. : . .: :. :** :* * : *.: ** **::****.*: *:.* :: * . * :: ::. * .** ** :** . * : ***:*: .:. **::. ::::: *:..:** . ** :. :: .: * : :*: *::::.. *: . : : ::: . ", "identical_positions": 187, "similar_positions": 360, "identity": "11.35%" }, { "cls_id": "homologset.agr.SGD:S000001812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4P9-1", "uniprot_id": "MRP7_MOUSE", "id": "Q8R4P9-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPRTTNHSPALNPGWRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGRSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQE-------PWTHDPFLSS--ESQETEVAEDGESWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQ-----------------------------------------LWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALKLGP---SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDP---------------IGASQKTFISH---LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTRLLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPLVQAVPTAWAEKEQVATSGQSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSLLLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMG--------------------GLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX04-1", "uniprot_id": "D3ZX04_RAT", "id": "D3ZX04-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAVLSACHLGTPRTNNIIQPFNPGWRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGHSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPRE-------PWTHDPFLSP--ESQEREVAEDGESWLSRFSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQ-----------------------------------------LWRALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLKLGP---SRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACVYLWAALPVVICIVIFITYVLLGHQLTATKVFTALALVHMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDP---------------TGTSQKTFISH---LQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDLSKGFGLATQEPWIQCATIRDNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKTLYLLDDPLAAVDADVANHLLHRCILGVLGHTTRLLCTHRTEYLERADLVLLMEAGRLVRAGPPSEILPLVQAAPTALADKEQVTDSGQSPSVHNLEKTT-EELDVAQNTSGRLVQEESKSEGAVALHVYRAYWRAMGSGLATAILISLLLMQATRNGADWWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGN----LLSIPLHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDIPQEPHGQPPQSPHQR-VSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLSEVAMAIG--------------------GLDGELGERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T3U5-1", "uniprot_id": "MRP7_HUMAN", "id": "Q5T3U5-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "------MERLLAQLCGSSAAWPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACYLGTPRSPDYILPCSPGWRLRLAASFLLSVFPLLDLLPVALPPGAGPGPIGLEVLAGCVAAVAWISHSLALWVLAHSPHGHSRGPLALALVALLPAPALVLTVLWHCQRGTLLPPLLPGPMARLCLLILQLAALLAYALGWAAPGGPRE-------PWAQEPLLP---EDQEPEVAEDGESWLSRFSYAWLAPLLARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGAR-----------------------------------------LWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYALGLAGGAVLGAVLQNQYGYEVYKVTLQARGAVLNILYCKALQLGP---SRPPTGEALNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFCGWEQALGARVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQLFLDLPNHNPQAYYSPDPPAEPSTVLELHGALFSWDP---------------VGTSLETFISH---LEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILGMLSYTTRLLCTHRTEYLERADAVLLMEAGRLIRAGPPSEILPLVQAVPKAWAENGQESDSATAQSVQNPEKTK-EGLEEEQSTSGRLLQEESKKEGAVALHVYQAYWKAVGQGLALAILFSLLLMQATRNAADWWLSHWISQLKAE-NSSQEAQPSTSPASMGLFSPQLLLFSPGNLY--IPVFPLPKAAPNGSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNATPTGRILNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLPPLSIMYYHVQRHYRASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQP----LQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLSEVITSMG--------------------GLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLV8-1", "uniprot_id": "A0A8M9QLV8_DANRE", "id": "A0A8M9QLV8-1", "name": "ATP-binding cassette sub-family C member 10", "aln": "MGGDIGAAEFISELCHTDVDSPFPVWQNGTISPCANQLLLGSLPHAVFAVISACYISVPRLIHIVSSLPIGWSLRAASTLLVFLLFIGDLVLVFELQAP---DIYLDTLADGCGILAFLVHFGAILSLQKSIYRRTRGPALLPVALILSIPNLAFNLTAYTQEIIHHGVSQPLQVIRLAFTVTRGALVLVYLLGYIFPCYRTQRDLLSCNAEDEAPLIVTFEPFEEVTVAEDGSSLLSRLLYLWLNPLLNRGKRGELERPSDVFELPSRLRTKSVTRRFYQCWEKCLQSRALKRPERPDRRPRGNLQDNSWSEAQPERICEGEAEHEVKLLQVLHKAFGLRYYLLGGLKLVASMLAFAGPLLLGGLVGFMETEGAPLSKGVWCTVGLFASTFLAALLKNIFVYEVSKVALEARAAVISTIYSKALKVNAPSLARFNMGEVVNFMSTDTDRVVNFFNSFHEVWSLPFQFVLALYLLYLQVGVAFLGGVGVAVLLVPLNKVLASRILENNKHMLQHKDGRVKLMTEILFGIRVLKYYNWEEHFTQKIEEARKKELHHLKLLKYLDAVCVYTWAALPVVISILTFITYVLLGNNLTAAKVFSTLALVGMLILPLNAFPWVLNGTLEAKVSLDRIQRFLAVQDQDLSVYYSQVCPEDPPSAVQMVQASFSWKQSEEADSVSIPDDITEEGSPPHSFYLHALNLNVKRGSLVVVVGKVGCGKSSLLAAITGELTRCGGEVFVQGREQGFGLAVQEPWIQHATVQDNILFGRDYDNMFYQSVIQACALADDLNILPGGDQTEVGENGVTLSGGQKSRLALARAVYMDKEIYLLDDPLAAVDADVAHHLMEKCILGILKDKTRILCTHRIEFVDKADVVVLMDNGMIVKTGTPSAVLSLVKGP-------KDSKNSSNAKEKDSAGSEEMEASEPELKAELEMFGEEQKQMGTLSWAVYRSYWKAVGGCMAVAVLLALFLMQASKNVSDWWLSHWISHMKDN-MTELVSVSATPLLMLSFLSPGRLVFNASARG--------SESSGNMSSELKFYMTVYGSLAAANTVFTAARAFLFAYGAICAATVIHKRLLSSVLKATMTFFDTTPLGRILNRFSSDIYSVDDSLPFVLNILLANVFGLLGMLIVMSYGLPWVLLPLVPLGALYYQTQCFYRYSSRELKRLCSLTLSPVYSHFSETLSGLSTVRASGHTTRFEEENERRLEQNQRCLFNSNAAMQWLDIRLQMIAVTVVTGISVIAVIQHQLKSIDPGLVGLSLSYALSITNLLSGLIFSYAQTEMQLVSIERTEEYSTSIPQEPQQAS----LEVSDRWPERARVEFVDVVLSYRPGLPNALDGVSVEVLPGEKIGIVGRTGSGKSSLFLALFRMVELNQGQILLDGVDISSVRLSDLRSKLAIIPQDPFLFSSSVRENLDPHGRHPDYRLLEALEQCHLGNVVQRNG--------------------GLDSEVGERGKSLSVGQRQLLCLARALLTEANILCIDEATASVDQKTDMLLQKTIREKFKDKTVLTIAHRLNTIMDSDKVLVMHAGKVVEFDSPATLCQREDSAFQKLLRGGEDQV--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CE69-1", "uniprot_id": "YK104_YEAST", "id": "P0CE69-1", "name": "Putative uncharacterized protein YKR104W", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSVERIKEY-TDIPSESNGYIS-----PPANWPQTGDVELKNLSLRYSPHSSKALDNVSFKVKAGTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIPLERLRNSISCIPQDPTLFDGTVRSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFEQEQPNFSSHKLRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARNIMLIDEATASIDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYDKILVMEMGRVKEYDHPYTLISDRNTIFYRLCRQSGEFENLFELAKVSFDNKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:** :** .:*.*.: * . **: :: * * * .:***.*:. * .* *:*******:****:: .::*: : . * : :*. * . : * **..:: ***:* **..::*.**** . : * : .*.: * : .*: : . * .** **********::* :*: *******:* :* :*:** . : :.*:*******.:::: *::**:. *:* * * * :* . .: * :* : . : ", "identical_positions": 99, "similar_positions": 86, "identity": "6.17%" }, { "cls_id": "homologset.agr.SGD:S000001839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70423-1", "uniprot_id": "CTR3_MOUSE", "id": "P70423-1", "name": "Cationic amino acid transporter 3", "aln": "-------------------MLWQALRRFGQKLVRRRVLE-------LGM-GETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGS-GSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLK--MPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKED----YCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHP-------ESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQ-----EMKSVEEEMELQEE--------------TLEAEKLTVQALFCPVNSIPTLLS--------------------------------------------------------------------------------GRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPL---HFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHS----------------------------------------------MKEVKNHQTLPKT------------RAQTIDL-------------------DLTTSCVHSI--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08812-1", "uniprot_id": "CTR3_RAT", "id": "O08812-1", "name": "Cationic amino acid transporter 3", "aln": "-------------------MLWQALRRFGQKLVRRRLLE-------LGM-GETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKEKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGS-GSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILLN--MPHVLAEYPDFFALALVLLLTGLLVLGANESGLVTKVFTGMNLLVLGFVIISGFIKGELRNWKLTKED----YCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQP-------ESPLPEAFTYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAFLFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQ-----EMKNGEEEVELQEER-------------TLEAEKLTVQALFCQVDSIPTLLS--------------------------------------------------------------------------------GRIVYVCSSLLAVLLTVLCLVLTWWTTPLHSGDPVWVTVVVLILGLILGISGVIWRQPQNRTPL---HFKVPVVPLLPLVSIFVNVYLMMQMTADTWARFGVWMLIGFAIYFGYGIQHS----------------------------------------------VEEVKNHQTLPKT------------RPQTIDL-------------------DLTTSCVHSI--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2R8QFJ7-1", "uniprot_id": "A0A2R8QFJ7_DANRE", "id": "A0A2R8QFJ7-1", "name": "", "aln": "-------------------MVLKKLLRFGKQLLRVKVVN-------CNS-EESRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVLSFLIAALASVLAGLCYAEFGARVPKT-GSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFDELIGKHIEHFCRQYMSMN--APGVLAEYPDMFSVFIILTLTGLLAFGVKESAMVNKVFTCINILVLLFMVVSGLVKGTLKNWHLDPDEILNATNSTLNATQPLPSEEMLGQGGFMPFGFTGVLSGAATCFYAFVGFDCIATTGEEVKNPQRAIPIGIVSSLLICFVAYFGVSAALTMMMPYYMLDK-------NSPLPVAFKYVGWEGATYAVAVGSLCALSTSLLGAMFPMPRVLWAMADDGLLFKFMAGISERTKTPIKATIMSGFLAAIMAFLFDLKDLVDLMSIGTLLAYTLVAACVLVLRYQPEQFSQTYHIANTHEDMEMSET-----ISTPSMGILPGVEERFSFKNLLFPDIIEPSNLS--------------------------------------------------------------------------------GFTVNICTSLLGLLILSFSLLAVRG--GIASWNIITLAVLFG---LCVIVTFIIWRQPESKTKL---SFKVPCLPFIPVVSMFVNVYLMMQLDRGTWIRFAIWMSIGLVIYFGYGIWHS----------------------------------------------TEAALAHSSMDEELSVYKPACGLNRDSVTPEK-------------------EAFLCNGHGSQVDDDGDI------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30823-1", "uniprot_id": "CTR1_RAT", "id": "P30823-1", "name": "High affinity cationic amino acid transporter 1", "aln": "-------------------MGCKNLLSLGQQMLRRKVVD-------CSR-EESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKT-GSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALN--APGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIMVSGFVKGSIENWQLTEN-----KSSPLCGNN--DTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDT-------DSPLPGAFKYRGWEEAKYAVAVGSLCALSTSPLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMARTTDELDQVDQNEMVSASESQTGFLP-AAEKFSLKTILSPKNMEPSKFS--------------------------------------------------------------------------------GLIVNISAGLLAVLIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKL---SFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIAFAIYFGYGVWHS----------------------------------------------EEASLAAG-----------------QAKTPDS-------------------NLDQCK------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18581-1", "uniprot_id": "CTR2_MOUSE", "id": "P18581-1", "name": "Cationic amino acid transporter 2", "aln": "------------------MIPCRAVLTFARCLIRRKIVT-------LDSLEDSKLCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKT-GSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMN--YTG-LAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSE-NGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE-------KSPLPVAFEYVRWSPAKYVVSAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYDQPKYTPEKETLESCTN--ATLKSESQVTMLQ--GQGFSLRTLFSPSAL-PTRQS--------------------------------------------------------------------------------ASLVSFLVGFLAFLILGLSILTTYGVQAIARLEAWSLALLALFLVLCVAVILTIWRQPQNQQKV---AFMVPFLPFLPAFSILVNIYLMVQLSADTWIRFSIWMALGFLIYFAYGIRHS----------------------------------------------LEGNPRDEEDDED------AFSDNINAATEEK-------------------SAMQANDHHQRNLSLPFILHEKTSEC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5D5N9-1", "uniprot_id": "CTR2_RAT", "id": "B5D5N9-1", "name": "Cationic amino acid transporter 2", "aln": "------------------MIPCRAVLTFTRCLIRRKIVT-------LDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKT-GSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMN--YTG-LAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSE-NGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE-------KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYTPEKDILESCTN--ATSKSESQVTMLQ--GQGFSLRTLFNPSAL-PTRQS--------------------------------------------------------------------------------ASLVSFLVGFLAFLIAGLSILTTYGVQAIARLEAWSLALLALFLVLCAAVILTIWRQPQNQQKV---AFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMVLGFLIYFAYGIRHS----------------------------------------------LEGNPRDEEEDED------VCPDNVNAAAEEK-------------------SAMQANDHHQRNLSLPFILHEKTSEC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "--------------MARGLPSTARLARFCQKLNRLKPLE-------ESS-TETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVW--QMPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWS-------------------------AEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDP-------DSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCPASPGPTVKKYDS--FSDHIQLVDAVQASMSEPGQLRPALKPFLGFLDGLSP-------------------------------------------------------------------------------GTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQD---TFQIPLVPLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHS----------------------------------------------KENQREPLELTTA-------HYVVFPSGSLEE-------------------TVQAVQPDSQTPVQGPGCTE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLQ7-1", "uniprot_id": "CTR4_MOUSE", "id": "Q8BLQ7-1", "name": "Cationic amino acid transporter 4", "aln": "--------------MARGLPSTACLARFCQKLNRLKPLE-------ESS-METSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVW--QVPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWS-------------------------AEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDP-------DSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCLASPGPTAKKYDS--FSDHIQLVGAEQTSMSEPGQLRPALKPFLGFLDGCSP-------------------------------------------------------------------------------GTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQD---TFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHS----------------------------------------------KENQREPLELTTA-------HYVVFPSGSLEE-------------------TVQAVQPSSQSPVRESGCTE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "--------------MARGLPTIASLARLCQKLNRLKPLE-------DST-METSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSW--QVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWS-------------------------ADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDP-------DSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGPASPGPLTKQQSS--FSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSP-------------------------------------------------------------------------------GAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYRED---LFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHS----------------------------------------------KENQRELPGLNST-------HYVVFPRGSLEE-------------------TVQAMQPPSQAPAQDPGHME----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "--MSGFFTSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWA--------------------------EGQ-FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDT-------ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKL---PYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "--MSGFLSSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWA--------------------------EGQ-FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDT-------ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKL---PYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPKLTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWS--------------------------EHQGFLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINT-------GAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYAL---AFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43548-1", "uniprot_id": "AGP3_YEAST", "id": "P43548-1", "name": "General amino acid permease AGP3", "aln": "----MAVLNLKRETVDIEETAKKDIKPYFASNVEAVDIDE--DPDVSRYDPQTGVKRALKNRHISLLALGGVIGPGCLVGAGNALNKGGPLALLLGFSIIGIIAFSVMESIGEMITLYPSG-GGFTTLARRFHSDALPAVCGYAYVVVFFAVLANEYNTLS---------SILQFWGPQVPLYG----------YILIFWFAFEIFQLVGVGLFGETEYWLAWLKIVGLVAYYIFSIVYISGDIRNRPAFG-------------------FHYWNSPGALSHGFKGIAIVFVFCSTFYSGTESVALAATESKNPGKAVPLAVRQTLWRILVVYIGIAVFYGATVPFDDPNLSASTKVLKSPIAIAISRAGWAGGAHLVNAFILITCISAINGSLYIGSRTLTHLAHEGLAPKILAWTDRR-GVPIPAITVFNALGLISLMN---------VSVGAANAYSYIVNLSGVGVFIVWGVISYTHLRIRKAWVAQGRS-----------------IEELPYEALFYPWTP----------------------------------------------------------------------------------------VLSLAANIFLALIQGWSYFVPFDAGNFVDAYILLPVGILLYIGICVFKSNHFRTVDLRSINLDEGRRKDMEADLSDQESSLASSETMKDYKSATFFRYLSNIFT--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : *.. .: *.:*. *.* : :* . . . .::: * : .: :. . .*: . * *. : .: . *: :: :. : : * * . . :: : . .: * . : . ::. . ..* * . * : * : :* :. * :** ::* .: :: .*. :: :*: . :.: * . :: .* : :* :** : :: * . . . : :*:*: *:: : : : : .: . : . : . : . * *: ", "identical_positions": 36, "similar_positions": 116, "identity": "4.17%" }, { "cls_id": "homologset.agr.SGD:S000001840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2N1-1", "uniprot_id": "AQP3_MOUSE", "id": "Q8R2N1-1", "name": "Aquaporin-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELMNRCGEMLH--IRYRLLRQALAEC--LG-------------------------------------------------------------------------------------TLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYALAQTLGAFLGAGIVFGLYYDAIWAFANNELFVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGRHWW-WVPIVSPLLGSIAGVFVYQLMIGCHLEQP--------PPSTEEENVKLAHMKHKEQI-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47862-1", "uniprot_id": "AQP3_RAT", "id": "P47862-1", "name": "Aquaporin-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELMNRCGEMLH--IRYRLLRQALAEC--LG-------------------------------------------------------------------------------------TLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLAILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWAFAGNELVVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGQNWW-WVPIVSPLLGSIGGVFVYQLMIGCHLEQP--------PPSTEAENVKLAHMKHKEQI-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92482-1", "uniprot_id": "AQP3_HUMAN", "id": "Q92482-1", "name": "Aquaporin-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELVSRCGEMLH--IRYRLLRQALAEC--LG-------------------------------------------------------------------------------------TLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWW-WVPIVSPLLGSIAGVFVYQLMIGCHLEQP--------PPSNEEENVKLAHVKHKEQI-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96PS8-1", "uniprot_id": "AQP10_HUMAN", "id": "Q96PS8-1", "name": "Aquaporin-10", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVFTQAPAEIMGHLR--IRSLLARQCLAEF--LG-------------------------------------------------------------------------------------VFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWW-WVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECKL-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A7W7-1", "uniprot_id": "A0A8I6A7W7_RAT", "id": "A0A8I6A7W7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTMACALLEIRAHLQ--IRSLMARQCLAEF--LG-------------------------------------------------------------------------------------VFVLLLLTQGSVAQAVTSEEKKGNYFTTCLASSLAVTIDIYVAGNVSGAHLNPAFSLAMCMVGRLPWAKLPIYCFVQLLSAFCASGATYVLYYDALQHYTGGNLTVTGPKETASIFATYPSPYLSLNNGFLDQVLGTWMLIVGLLAILDRQNKGVPAGLEPVVVGLLILTIGLSMGVNCGSPLNPARDLGPRLFTYFAGWGPDVFSAGNGWW-WVPVVAPMVGATLGTATYQLLVALHHPED--------SSQLKTSDLVT---LTQLECKL-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58I859-1", "uniprot_id": "A0AC58I859_DANRE", "id": "A0AC58I859-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRQLIQHVALPAATHLRETHTHTHTHTH--TTDNLAYPIYLHFGLWGKPDYPEHPIGVCNGCHRTTAQVC----------------------------------------------SLHNSYWWSGETVMEPIWWMEVFGLGTVAQVVTGEGYFGEYLSINIGFGLAVAMGVHVGGKVSGAHMNAAVSFTMCVFGRLRWKMLPLYVFAQFLGSFLAAGTIFSLYYDAINHFCGGNLTVSGPKATAGIFATYPAPYISVYTGFFDQVAGTGLLLLCLMALSDQRNQPLVSGGEAVGVGLLVMLIGVSMGSNSGYAINPTRDLGPRLFTLMAGWGTEVFRAGNCWW-WVPLVAPFIGGVLGALIYKALVELHHPDLKSTITR-PAVDPECIPLDKCK-NGRIEIPV-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JJJ3-1", "uniprot_id": "AQP9_MOUSE", "id": "Q9JJJ3-1", "name": "Aquaporin-9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEKDRAKKNLVQRLA--LKSCLAKETLSEF--LG-------------------------------------------------------------------------------------TFIMIVLGCGSIAQAVLSREKAGGIITINIGFATAVVMALYATFGVSGGHINPAVSFAMCTFGRMEWFKFPFYVGAQLLGAFVGAATVFGIYYDGLMAFADGKLLITGENGTAFIFATYPKPFVSVPGAFVDQVVSTMFLLLIVFAIFDSRNLGVPRGLEPIVIGLLIIVISCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTFGNNFW-WIPVVGPMIGAVLGGLIYVLFIQMHHSNP--------DPEVKAEPAENNLEKHELSVIM-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56627-1", "uniprot_id": "AQP9_RAT", "id": "P56627-1", "name": "Aquaporin-9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEKDGAKKSLMQRLA--LKSRIAKETLSEF--LG-------------------------------------------------------------------------------------TFIMIVLGCSSIAQAVLSRERFGGIITINIGFASAVVMALYVTFGISGGHINPAVSFAMCAFGRMEWFKFPFYVGAQFLGAFVGAATVFGIYYDGLMAFAGGKLLVVGENATAFIFATYPAPFISTPGAFVDQVVSTMFLLLIVFAMFDSRNLGVPRGLEPVVIGLLIIVLSCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTVGNNFW-WIPVVGPMIGAFLGGLIYILFIQMHHSKL--------DPDMKAEPSENNLEKHELSVIM-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43315-1", "uniprot_id": "AQP9_HUMAN", "id": "O43315-1", "name": "Aquaporin-9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPEGAEKGKSFKQRLV--LKSSLAKETLSEF--LG-------------------------------------------------------------------------------------TFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFW-WIPVVGPLVGAVIGGLIYVLVIEIHHPEP--------DSVFKTEQSEDKPEKYELSVIM-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54794-1", "uniprot_id": "AQP7_MOUSE", "id": "O54794-1", "name": "Aquaporin-7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRSVLETIQSVL----QKNMVREFLAEF--LS-------------------------------------------------------------------------------------TYVMMVFGLGSVAHMVLGE-NSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWW-WVPVVAPLLGAYLGGIVYLGLIHPSIPQDPQRLENFTARDQKVTASYKNAASAN------------------------ISGSVPLEHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56403-1", "uniprot_id": "AQP7_RAT", "id": "P56403-1", "name": "Aquaporin-7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-SVLENIQSVL----QKTWVREFLAEF--LS-------------------------------------------------------------------------------------TYVLMVFGLGSVAHMVLGE-RLGSYLGVNLGFGFGVTMGIHVAGGISGAHMNAAVTFTNCALGRMAWKKFPIYVLGQFLGSFLAAATTYLIFYGAINHYAGGELLVTGPKSTANIFATYLPEHMTLWRGFVDEVFVTGMLQLCIFAITDKLNSPALQGTEPLMIGILVCVLGVSLGMNTGYAINPSRDLPPRFFTFIAGWGKKVFSAGNNWW-WVPVVAPLLGAYLGGIVYLGLIHAGIP--PQ-------------------------------------------------GS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14520-1", "uniprot_id": "AQP7_HUMAN", "id": "O14520-1", "name": "Aquaporin-7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQASGHRRSTRGSKMVSWSVIAKIQEIL----QRKMVREFLAEF--MS-------------------------------------------------------------------------------------TYVMMVFGLGSVAHMVLNK-KYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWW-WVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B734-1", "uniprot_id": "AQP7B_HUMAN", "id": "A0A075B734-1", "name": "Putative aquaporin-7B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEF--MS-------------------------------------------------------------------------------------TYVMMVFGLGSVAHMVLNK-TYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYSLFYTAILHFSGGELMVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWW-WVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43549-1", "uniprot_id": "AQY3_YEAST", "id": "P43549-1", "name": "Aquaglycerol porin AQY3", "aln": "MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFS-LGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRYHMREPFAEFLGTLVLVIFGVGGNLQATVTKGSGGSYESLSFAWGFGCMLGVYVAGGISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRT--TATGACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPVNYPDNGYIENRVGKLLHAEFHQNDGTVSDESGVNSNSNTGSKKSVPTSS---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: . : * .. . . : : :**.*:*.*.::: . . : * .*.: * :.:: ... : : .: : .. *. : * .: .* :: : * :::: * * * .. :.::: : : * : . .:**:** * :*: . *:* .* . :* * . .*: *. * * .: ", "identical_positions": 32, "similar_positions": 80, "identity": "4.86%" }, { "cls_id": "homologset.agr.SGD:S000001841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLZ6-1", "uniprot_id": "TKFC_RAT", "id": "Q4KLZ6-1", "name": "Triokinase/FMN cyclase", "aln": "MSSKKMVNSVEGCAGDALAGFVACNPDLQLLQGYRVALRSDLDSLKG---RVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFASPAVGSILAAIRAVAQAGTAGTLLIVKNYTGDRLNFGLAMEQAKAEGISVEMVVIEDDSAFTVLKK--AGRRGLCGTILIHKVAGALAEEGMGLEEITKKVSVIAKAIGTLGVSLSPCSVPGTKPTFELAADEMELGLGIHGEAGVRR-IKLVPVDQIVTLMLDHMTD-TSNISHVPVKSGSSVVLMVNNLGGLSFLELGIIADAA-IRLLEGRGVKVARALVGTFMSALEMRGVSLTLMLVDEP---LLKLIDAETNAKAWPHMSKVS----VTGRNRIRAAPTEPAEAPEATAAGGVASKQMTLVLDRISTTLIGLEEHLNALDRAAGDGDCGSTHSRAAKAIQGWLKEGPT-PASPAQVLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKANTD----LPAWSAAMDAGLKAMQKYGKAAPGDRTMLDSLWAAAQELQAWKSPGASLLPVLTKAVKSAEAAAEATKNMEAGAGRASYISSAQLDQ-------PDPGAVAAAAIFRAILEVLQTKAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC30-1", "uniprot_id": "TKFC_MOUSE", "id": "Q8VC30-1", "name": "Triokinase/FMN cyclase", "aln": "MSSKKMVNSVEGCADDALAGLVASNPDLQLLQGHRVALRSDLDTLKG---RVALLSGGGSGHEPAHAGFIGKGMLTGVIAGSVFASPPVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAMEQAKAEGISVEMVIVEDDSAFTVLKK--AGRRGLCGTVLIHKVAGALAEEGMGLEEITKRVSVIAKTMGTLGVSLSSCSVPGATHTFELAADEIELGLGIHGEAGVRR-IKIAPVDQIVTLMLDHMTN-TSNIFHVPVRSGSSVVLIVNNLGGLSFLELGIIADAA-IRLLEGRGVKVARALVGTFMSALEMPGVSLTLMLVDEP---VLKLIDAETTAKAWPHMAKVS----VTGRKRIRAAPTEPPEAPEATAAGGVTSKQMALVLDRICTTLIGLEEHLNALDRAAGDGDCGSTHSRAAKAIQGWLKEGPS-LTSPAQVLSRLSVLLLERMGGSSGALYGLFLTAAAQPLKAKTD----LPTWSAAMDAGLESMQKYGKAAPGDRTMLDSLWAAAQEFQAWKSPGASLLPVLTKAVKSAEAAAEATKNMEAGAGRASYISSAQLDQ-------PDPGAVAAAAIFRAILEVLQTQGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3LXA3-1", "uniprot_id": "TKFC_HUMAN", "id": "Q3LXA3-1", "name": "Triokinase/FMN cyclase", "aln": "MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKG---RVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKK--AGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRR-IKMATADEIVKLMLDHMTN-TTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADAT-VRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEP---LLKLIDAETTAAAWPNVAAVS----ITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEGPP-PASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTS----LPAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQ-------PDPGAVAAAAILRAILEVLQS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43550-1", "uniprot_id": "DAK2_YEAST", "id": "P43550-1", "name": "Dihydroxyacetone kinase 2", "aln": "-MSHKQFKSDGNIVTPYLLGLARSNPGLTVIKHDRVVFRTASAPNSGNPPKVSLVSGGGSGHEPTHAGFVGEGALDAIAAGAIFASPSTKQIYSAIKAVESP--KGTLIIVKNYTGDIIHFGLAAERAKAAGMKVELVAVGDDVSVGKKKGSLVGRRGLGATVLVHKIAGAAASHGLELAEVAEVAQSVVDNSVTIAASLDHCTVPGHKPEAILGENEYEIGMGIHNESGTYKSSPLPSISELVSQMLPLLLDEDEDRSYVKFEPKEDVVLMVNNMGGMSNLELGYAAEVISEQLIDKYQIVPKRTITGAFITALNGPGFGITLMNASKAGGDILKYFDYPTTASGWNQMYHSAKDWEVLAKGQVPTAPSLKTLRNEKGSGVKADYDTFAKILLAGIAKINEVEPKVTWYDTIAGDGDCGTTLVSGGEALEEAIKNHTLRLEDAALGIEDIAYMVEDSMGGTSGGLYSIYLSALAQGVRDSGDKELTAETFKKASNVALDALYKYTRARPGYRTLIDALQPFVEALKAGKGP--------RAAAQAAYDGAEKTRKMDALVGRASYVAKEELRKLDSEGGLPDPGAVGLAALLDGFVTAAGY---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 190, "similar_positions": 207, "identity": "31.4%" }, { "cls_id": "homologset.agr.SGD:S000001846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G604-1", "uniprot_id": "A0A8I6G604_RAT", "id": "A0A8I6G604-1", "name": "", "aln": "MGGRAGGSAGQWVGPRGGLFDEGPAVGKMAAAPRPS-WWQRWRRRAWARDGA--------RLLLFLLLLGSGSGPGPLHVRAGQAV------------EYLKREHSLSKPYQGVGTSSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLKD-WELQVHFKIHGQGKKNLHGDGLAIWYTKDRM--QPGPVFGNMDKFVGLGVFVDTYPNEEKQHEAQKRRYSPGVQRVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNIRYDTFLVIRYVKRHLTIMMD---IDGRHEWRDCIEMPGVRLPRGYY-FGTSSITGDLS-DNHDVISLKLFELTGVRTPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKLHRDVFLPSVDNLKLP-EMTEPPT------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQDHSRKRFY--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59481-1", "uniprot_id": "LMA2L_MOUSE", "id": "P59481-1", "name": "VIP36-like protein", "aln": "----------------------------MAAASRPS-WWQRWRRRAWARDGA--------KLLLFLLLLGSG--PGPRHVRAGQAV------------EYLKREHSLSKPYQGVGTSSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLKD-WELQVHFKIHGQGKKNLHGDGLAIWYTKDRM--QPGPVFGNMDKFVGLGVFVDTYPNEEKQHER-----------VFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNIRYDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEMPGVRLPRGYY-FGTSSITGDLS-DNHDVISLKLFELTGVRTPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKLHRDVFLPSVDNLKLP-EMTVPPT------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQDQSRKRFY--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0V9-1", "uniprot_id": "LMA2L_HUMAN", "id": "Q9H0V9-1", "name": "VIP36-like protein", "aln": "----------------------------MAATLGPLGSWQQWRRCLSARDGS--------RMLLLLLLLGSG--QGPQQVGAGQTF------------EYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRD-WELQVHFKIHGQGKKNLHGDGLAIWYTKDRM--QPGPVFGNMDKFVGLGVFVDTYPNEEKQQER-----------VFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEVPGVRLPRGYY-FGTSSITGDLS-DNHDVISLKLFELTVERTPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKLHRDVFLPSVDNMKLP-EMTAPLP------------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBH5-1", "uniprot_id": "LMAN2_MOUSE", "id": "Q9DBH5-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "----------------------------MAAEAWLWRWGWGWGQRCPGRPGLPGPGPSPTTFLHLLLLLGPV----AADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKD-WEMHVHFKVHGTGKKNLHGDGIALWYTRDRL--VPGPVFGSKDNFHGLAIFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDITGVRLPTGYY-FGASAGTGDLS-DNHDIISIKLFQLTVERTPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESIDWTKIEPGVNFLKSPKDNVDDPTGNF------RNGPLTGWRVFLLLLCALLGVVVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FPK8-1", "uniprot_id": "F7FPK8_RAT", "id": "F7FPK8-1", "name": "", "aln": "----------------------------MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLGLV----AADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKD-WEMHVHFKVHGTGKKNLHGDGIALWYTRDRL--VPGPVFGSKDNFHGLAVFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDVTGVRLPTGYY-FGASAGTGDLS-DNHDLISIKLFQLTVERTPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESIDWTKIEPGVNFLKSPKDNVDDPTGNF------RGGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12907-1", "uniprot_id": "LMAN2_HUMAN", "id": "Q12907-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "----------------------------MAAEGWIWRWGWGR--RCLGRPGLLGPGPGPTTPLFLLLLLGSV----TADITDGNS-------------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKD-WEMHVHFKVHGTGKKNLHGDGIALWYTRDRL--VPGPVFGSKDNFHGLAIFLDTYPNDETTER------------VFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDITGVRLPTGYY-FGASAGTGDLS-DNHDIISMKLFQLMVEHTPD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESIDWTKIEPSVNFLKSPKDNVDDPTGNF------RSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERN-KRFY--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0F3-1", "uniprot_id": "LMAN1_MOUSE", "id": "Q9D0F3-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAVSRRRVPQAGA--------RSFFCALLLSFSQFTGSDGTGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKAKAAFEN-WEVEVTFRVTGRGR--IGADGLAIWYTENQG--LDGPVFGSADTWNGVGIFFDSFDNDGKKNN--------------PAIVVIGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGH-FGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTAEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQ--GQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLT----EEISRRGAGTPGQP----GQVSQQELDTVVKSQQEILRQVNEVKNSMS----ETVRLVSGIQHPGSAG----VYETTQHFMDIKEHLHVVKRDIDSLAQRSMPSNEKPKCPDLPPFPSCLSTIHFVIFVVVQTVLFVGYIMYRTQQEAAAKKFF--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62902-1", "uniprot_id": "LMAN1_RAT", "id": "Q62902-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAVSRRRGPQAGA--------QSFFCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKTKAAFEN-WEVEVTFRVTGRGR--IGADGLAIWYTENQG--LDGPVFGSADMWNGVGIFFDSFDNDGKKNN--------------PAIVVVGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGH-FGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQ--GQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLT----EEISRRGAGTPGQP----GQVSQQELDTVVRTQLEILRQVNEMKNSMR----ETMRLVSGVQHPGSAG----VYETTQHFMDIKEHLHIVKRDIDSLAQRSMSSNEKPKCPDLPAFPSCLSTVHFVIFIVVQTVLFIGYIMYRTQQEAAAKKFF--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49257-1", "uniprot_id": "LMAN1_HUMAN", "id": "P49257-1", "name": "Protein ERGIC-53", "aln": "---------------------------------------MAGSRQRGLRARV--------RPLFCALLLSLGRFVRGDGVGGDPAVA--------LPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFEN-WEVEVTFRVTGRGR--IGADGLAIWYAENQG--LEGPVFGSADLWNGVGIFFDSFDNDGKKNN--------------PAIVIIGNNGQIHYDHQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGH-FGISAATGGLA-DDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQ--GQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLT----EEISKRGAGMPGQH----GQITQQELDTVVKTQHEILRQVNEMKNSMS----ETVRLVSGMQHPGSAGG---VYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVHFIIFVVVQTVLFIGYIMYRSQQEAAAKKFF--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3S9-1", "uniprot_id": "A0AB13A3S9_DANRE", "id": "A0AB13A3S9-1", "name": "", "aln": "---------------------------------------MAVPIAKCLAAYA--------HLLIISVIFPH---LFADSATGD------------LPHRRFEYKYSFKGPHLTQSDGRIPFWIHTGNAIPSSDQVRITPSLRSQKGSVWTKSPVSFEH-WEAEVAFRVSGRGR--MGADGLAIWFTAGQG--LEGPVYGAADQWNGVGIFFDSFDNDGKKNN--------------PAVLVVGNNGKLVFDHQNDGTTQALGTCLRDFRNKPYPIRTKITYYKQTLSVFINNGFTPDKDDYEFCTKVENMIIPGTGY-FGISAATGGLA-DDHDVLSFLLFRLTEPGQNLPPPEKEIPKEEKDKYQEEFENFQQALDKRKEEFQKEHPDVQ--GQPIEDLYESVNDREIRQVFEGQNRIHLEIKQLNRQLAMILDEQRRYVSVIT----DEINKRTS--QAQS----GQAPSHELETIITTQHEVLKNINEVRNSLS----GSLKQLAMGQHQGNAGGL-GSYETVQHFNDIKEHLHVVKRNIEHIIQKNANPAEKLKCPELPPLPTCLSTTHFLIFIVIQSLLFFGYIMYKSQQEAAAKKFF--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3A8-1", "uniprot_id": "Q9V3A8_DROME", "id": "Q9V3A8-1", "name": "", "aln": "-----------------------------------------------MRPTF--------LAILCFLAWNPSSEATGNLSPGAVG-----------VHRRFEYKYSFKPPYLAQKDGTVPFWEYGGNAIASSESVRVAPSLRSQKGAIWTKSQTNFDW-WDVEIVFRVTGRGR--IGADGLAFWYTTEKGD-YNGPVFGSSDRWNGLAIMFDSFDNDNKHNN--------------PYISAVLNDGTKLYDHAEDGTTQLLSGCLRDFRNKPFPTRARIEYYNNVLTVMIHNGMSNNNDDYELCLRADGVNLPKNGY-FGISAATGGLA-DDHDVFHFLTTSLHAAGQVQEQPK----VENQEKLTQEYKEYQDKLEKQKQEYKKDHPDEHKDEEDWEEFYESENQRELRQIWQGQSQIADHLRELSRKVDEIIGRQETTLSLVSRNAGQALPPPAAGGVPQQQLPVGAVSRSDVDLLLTNQNMLLSSIREIRQLVGDINVRTDNIQTNQKHAPTAQIQSTGYDVQTLIAEMRDGMNQVKQGITHVGQRLAAPQGAAQVANCPTG-NCVGVTLFLSVTVVQLLLVFIYNVFKNRSEAQAKKFY--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8VCD3-1", "uniprot_id": "LMA1L_MOUSE", "id": "Q8VCD3-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MLEIRGL--------SPSLCLLSLLLVLHGAERSQPPP--------------RRRFEYKLSFKGPRLAVPGAGIPFWSHHGDAILGLEEVRLVPSMKNRSGAVWSNISVSFPS-WEVEMQMRVTGPGR--RGAQGVAMWYTKDRA--QVGSVVEELASWDGIGIYFDSSTSD-VQDS--------------PVIRVLASDGHDLQEQSGDGNVRELGSCHRDFRNRPFPFRARVTYWRQRLRVSLSGGLTP-KDPEEVCVDVEPLFLAPGGF-FGVSAATGTLAADDHDVLSFLTFSLREPGPEETPQPFMEKDQLLLARKLEELKARLALGTREASIPPLNPKAQEEGERFFNLEDTLGRQ--SQILQALQALSRQMAQAEKHWKQQLGSTVQVRPEGGWN------------------------TAKVSTLLYGQRTLIQALQEMR-------------EAAARMASGAHVFYLPVGTKHHFFELDHILSLLQKDLRGLVKKTAKAPRPS--GWLLGSSTCLHTSIFLFFLLLQTVGFFCYVNFSRQELDKRLQEYLSTGSLSLEPALPITRTIGVLRRQPISPSMQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FB95-1", "uniprot_id": "LMA1L_RAT", "id": "Q5FB95-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MLKTGGL--------SPSLCLLSLLLALHSAERSYPPP--------------QRRFEYKLSFKGPRLAVPGAGIPFWSHHGDAIPGLEEVRLVPSMKNRSGAVWSEISVSFPS-WEVEMQMRVTGPGR--RGALGVAMWYTKDRD--QVGSVVEGLASWDGIGIYFDSSSND-VQNG--------------PAIRVLASDGHDLQEQFGDGTVRELGSCLRDFRNRPHPFRARITYWRQRLRVSLSGGLTP-NDPEEVCVDVEPLLLAPGGF-FGVSAATSTLA-DDHDVLSFLTFSLRDPGSEEALQPFTEKEQFHLARKLEELKARLALGTREDTILPLNSKAQEEGERFFNLEDTLSRQ--SQILQALQALSRQMDQAEKQWKQQLGSVVQIRPEGGWN------------------------TAKVSTLLYGQRTLIQALQEMR-------------EAAAQMASGAQVFYLPVGTKHHFFELDQTLGLLQKDLRDLVKMTAKPPRPS--GWLPGFSTCLRTSIFLFFLLIQTVGFFCYMNF-RQELDKRLQEYLFTESISLQPALPIPRTIGVLRRQPVSPSMQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HAT1-1", "uniprot_id": "LMA1L_HUMAN", "id": "Q9HAT1-1", "name": "Protein ERGIC-53-like", "aln": "---------------------------------------------MPAVSGP--------GPLFCLLLLLLDPHSPETGCPP---------------LRRFEYKLSFKGPRLALPGAGIPFWSHHGDAILGLEEVRLTPSMRNRSGAVWSRASVPFSA-WEVEVQMRVTGLGR--RGAQGMAVWYTRGRG--HVGSVLGGLASWDGIGIFFDSPAED-TQDS--------------PAIRVLASDGHIPSEQPGDGASQGLGSCHWDFRNRPHPFRARITYWGQRLRMSLNSGLTP-SDPGEFCVDVGPLLLVPGGF-FGVSAATGTLA-DDHDVLSFLTFSLSEPSPEVPPQPFLEMQQLRLARQLEGLWARLGLGTREDVTPKSDSEAQGEGERLFDLEETLGRH--RRILQALRGLSKQLAQAERQWKKQLGPPGQARPDGGWALDASCQIPSTPGRGGHLSMSLNKDSAKVGALLHGQWTLLQALQEMR-------------DAAVRMAAEAQVSYLPVGIEHHFLELDHILGLLQEELRGPAKAAAKAPRPP--GQPPRASSCLQPGIFLFYLLIQTVGFFGYVHF-RQELNKSLQECLSTGSLPLGPAPHTPRALGILRRQPLPASMPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43555-1", "uniprot_id": "EMP47_YEAST", "id": "P43555-1", "name": "Protein EMP47", "aln": "-------------------------------------------MMMLITMKS--------TVLLSVFTVLATWAGLLEAHPLGDTS------------DASKLSSDYSLPDLINARKVPNNWQTGEQASLEEGRIVLTSK-QNSKGSLWLKQGFDLKDSFTMEWTFRSVGYSG--QTDGGISFWFVQDSNVPRDKQLYNGPVNYDGLQLLVD----NNGPLG--------------PTLRGQLNDGQKPVDKTK-IYDQSFASCLMGYQDSSVPSTIRVTYDLE------DDNLLKVQVDNKVCFQTRKVRFPSGSYRIGVTAQNGAVN-NNAESFEIFKMQFFNGVIEDSLIPN----VNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSK---------------------------------------------------------PPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHG-----QDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . * * .: : :... :. *::* . : : . :: * . *::.*:. : : *: : .* : * : .:* :: :. * :: : * . * : : . :* :: .. : :: : : : : : : : : .. : . : ", "identical_positions": 15, "similar_positions": 68, "identity": "2.36%" }, { "cls_id": "homologset.agr.SGD:S000001847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97814-1", "uniprot_id": "PPIP1_MOUSE", "id": "P97814-1", "name": "Proline-serine-threonine phosphatase-interacting protein 1", "aln": "MMAQLQFRDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDVEELLRQRAQAEERYGKELVQIA-------RKAGGQTEMNSLRTSFDSLKQQTENVGSAHIQLALALREELRS-LEEFRERQKEQRKKYEAIMDRVQKSKLSLYKKTMESKKAYDQKCRDADDAEQAFERVS--ANGHQKQVEKSQNKAKQCKESATEAERVYRQNIEQLERARTEWEQEHRTTCEAFQLQEFDRLTILRNALWVHCNQLSMQCVKDDELYEEVRLTLEGCDVEGDINGFIQSKSTGREPPAPVPYQNYYDREVT----------------------------------------------------------------------PLIGSPSIQPSCG------------------VIKRFSG-------LLHGSPKTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSAPAASTETLTPTPERNELVYASIEVQATQ----GNLNSSAQDYRA------LYDY--------------------------------------------------TAQNSDE----------LDISAGDILAVILEGE-----------DGWWTVERN-GQRGFVPGSYLEKL--------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43586-1", "uniprot_id": "PPIP1_HUMAN", "id": "O43586-1", "name": "Proline-serine-threonine phosphatase-interacting protein 1", "aln": "MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA-------RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRS-LEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERIS--ANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVT----------------------------------------------------------------------PLTSSPGIQPSCG------------------MIKRFSG-------LLHGSPKTTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAASAASTETLTPTPERNEGVYTAIAVQEIQ----GNPASPAQEYRA------LYDY--------------------------------------------------TAQNPDE----------LDLSAGDILEVILEGE-----------DGWWTVERN-GQRGFVPGSYLEKL--------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G0H7-1", "uniprot_id": "A0AC58G0H7_DANRE", "id": "A0AC58G0H7-1", "name": "", "aln": "--MALLFCDSFWGTDFTDQSGYEAILQRLQDGRHMCKDVEELLKMRALAEEKYGRDLVAIA-------RKAEGQTEIGTLKASFDKFKEEIEKTGNLHIQLSERIKEEVLK-IEVFREHQREQRKKLEEIIEKLQKPKMVLHKKTMESKRLYEQRCKEADESEQALGKKTNVNTSTHRQSEKVMNRARLCRQAANLAEKQYRWNVDQLGKTCQDWESTYRSACEVFQQQESERINILRCVLWEHCNLLSKQCVQDDDCYEEVRKILEQCDIVADNNNFIKMKKTSSHPPAPIEFQCYSDADTNGGV----------------------------------------------------RRIETNRLSVVLSGMSFIGFPEAGNNSGAKYTPDQQRIGVTEEKYMVLYEFKAQEDDELSISKGQVVTITEKDSQEEVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFKADGKNHMSTESWVGLSKPSATGEWVWSDGSQESFLTWKSGQPNDPDTDFCAKSTNGELFDFNCNQKYPFFCYYWMPPLILVMELKSWEEAFQYCRTKHNGLACLPTRLHLLQVQNHTEASDAPSVWTGLRFLAGSWFWVNGEALGTLVSLQACPANALYCGSRNLGAKSWENRNCIDKLNFVCY---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99M15-1", "uniprot_id": "PPIP2_MOUSE", "id": "Q99M15-1", "name": "Proline-serine-threonine phosphatase-interacting protein 2", "aln": "-MTGSLFKGNFWSTDILSTIGYDSIIQHLNNGRKNCKEFEDFLKERASIEEKYGKDLLNLSR------KKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQTLREEARK-MEEFREKQKLQRKKTETIMDAAHKQRNAQFKKAMDAKKNYEQKCRDKDEAEQAVHRSAN--VANQRQQEKLFVKLATSKTAVEDSDKAYMLHINMLEKVREDWQSEHIKACEVFEAQECERINFFRNALWLHLNQLSQQCVANDEMYEQVRKSLETCSIEKDIQYFVNQRKTGQTPPAPIMYENFYSPQRN--------------------------------------------------------------------------AAPPGKTTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNPARRGPLPVPKRI--------------------PDDPDYSVVED--YSLLYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LW07-1", "uniprot_id": "A0ABK0LW07_RAT", "id": "A0ABK0LW07-1", "name": "Proline-serine-threonine phosphatase-interacting protein 2", "aln": "-MTGSLFKGNFWSTDILSTVGYDSIIQHLNNGRKNCKEFEEFLKERASIEEKYGKDLLNLSR------KKPCGQSEINTLKRALDVFKQQVDNVAQCHIQLAQTLREEARK-MEEFREKQKLQRKKTETIMDAAHKQRNSQFKKAMDAKKNYEQKCRDKDEAEQAVHRSAN--MANQRQQEKLFVKLATSKTAVEDSDKAYMLHINMLEKVREDWQSEHIKACEVFEAQECERINFFRNALWLHVNQLSQQCVTNDEMYEQVRKSLETCSIEKDIQYFVNQRKTGQVPPAPIMYENFYSPQRN--------------------------------------------------------------------------AAPPAKTAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHPARRGPLPVPKRI--------------------PDDPDYSLVED--YSLLYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H939-1", "uniprot_id": "PPIP2_HUMAN", "id": "Q9H939-1", "name": "Proline-serine-threonine phosphatase-interacting protein 2", "aln": "-MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSR------KKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSAN--LVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKN--------------------------------------------------------------------------AVPAGKATG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNLARRGPLPIPKSS--------------------PDDPNYSLVDD--YSLLYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCU8-1", "uniprot_id": "A0A8M3BCU8_DANRE", "id": "A0A8M3BCU8-1", "name": "Proline-serine-threonine phosphatase-interacting protein 2", "aln": "-MREQHFKDNFWNTDITSTAGYDTIIQHLNDGKRTCKEIEDFMKARAAIEEKYAKELLGLS-------KKVCGHSEMNTLKRSLDVFKLQTENMSLSHLHLAQTMREEAKK-LEDFREKQKEARKKVEQQMDALHKQKAAQYKKTAEAKKSYDQKCRDKEETEQNMNRSAT--TCSAKQQEKLYAKTQQAKQAAEEADRIYSQNVSVLGKMREEWLNEHVKACEFFEKQEVERINTLRNIVWTHLNHLSQQCVSSDEIYEEVRKSLEQCNIQEDIEHFVNLRRTGDKPPAPIPYENFYNNQR------------------------------------------------------------------------------SGVVRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPPPRRAAAPPPPAA--------------------GNDPLYSTVAEPGYSILRY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UQN2-1", "uniprot_id": "FCHO2_MOUSE", "id": "Q3UQN2-1", "name": "F-BAR domain only protein 2", "aln": "-MVMAHFVENFWG---EKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA-------KSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKE-VQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQE------------RLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPASAVEG---------IKPRKRKTFALPGIIKKEKDAESVECPDADSLN-------------------IPDVDEEGFSIKPEANQNDTKENHFYSSSDSDSEDEEPKRYRIEIKPAHPNN-LHHTMASLDELKVSIGNITLSPAVSRHSPVQMNRNSSNE-ELTKSKPSSLPTEK--GTNDLLAWDPLFGSSLE----------------SSS-APLTSSSS-ARPTTPLSLGTLVPP--------PRPASRPKLASGKLSGINEI------------PRPFSP--------------------------------PVTSNTSPPP---TAPLARAESSSSISSSASLSAANTPTVG--------------------VSRGPSPVSLGNQDTLPVAIALTESVNAYFKGADPTKCIVKITGDVTISFPSG-IIKVFTSNPSPAVLCFRVKNISRLEQILPNSQLVFSDPSQCDSNTKDFWMNMQAVTIYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYLADC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZYR1-1", "uniprot_id": "FCHO2_RAT", "id": "D3ZYR1-1", "name": "F-BAR domain only protein 2", "aln": "-MVMAHFVENFWG---EKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA-------KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKE-VQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYNAKCVEQE------------RLKKEGATPREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPASAVEG---------IKPRKRKTFALPGIIKKEKDAESVECPDADSLN-------------------IPDVDEEGFSIKPEANQNDTKENHFYSSSDSDSEDEEPKRYRIEIKPVHPNN-VHHTMASLDELKVSIGNITLSPAVSRHSPVQMNRNSSNE-ELTKSKPSSLPTEK--GTNDLLAWDPLFGSSLE----------------SSS-APLTSSSS-ARPTTPLSLGTIVPP--------PRPASRPKLTSGKLSGINEI------------PRPFSP--------------------------------PITSNTSPPP---TAPLARAESSSSISSSASLSAANTPTVG--------------------VSRGPSPVSLGNQDTLPVAIALTESVNAYFKGADPTKCIVKITGDVTISFPSG-IIKVFTSNPSPAVLCFRVKNISRLEQILPNSQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPATLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYLADC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0JRZ9-1", "uniprot_id": "FCHO2_HUMAN", "id": "Q0JRZ9-1", "name": "F-BAR domain only protein 2", "aln": "-MVMAYFVENFWG---EKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA-------KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKE-VQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE------------RLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEG---------IKPRKRKTFALPGIIKKEKDAESVECPDADSLN-------------------IPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNN-SHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNE-ELTKSKPSAPPNEK--GTSDLLAWDPLFGPSLD----------------SSSSSSLTSSSS-ARPTTPLSVGTIVPP--------PRPASRPKLTSGKLSGINEI------------PRPFSP--------------------------------PVTSNTSPPP---AAPLARAESSSSISSSASLSAANTPTVG--------------------VSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSG-IIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502I9-1", "uniprot_id": "FCHO2_DANRE", "id": "Q502I9-1", "name": "F-BAR domain only protein 2", "aln": "-MITPYFLENFWG---NKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLA-------KTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKE-VQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQE------------RMRKEGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESRGTGKERPGPIEFEECNVSIATEG---------AKPRKRKTFAIPGRRK-EKDTDSTESTEVEAVNASNGAPPGFYGAIDLHNANVPQLDDEGFCIRPEVNENDAKENSFYSSSDSEDEDE-PRKFHVQIKPVQTNNGTHQHKVTIDELKASIGNISLSPTP----AVHMKRNQSND-ELARPKIPQPPLNDRFSSNDLLSLDPFGPTSTG----------------SSSSLPQSSVPPPNRPTTPLGTSSIVPP--------PRPLSRPKLATGKLTGITES------------GRPFSP--------------------------------PKLLNSSPPPP--AAPLARAESFSSLSSNTSLSASNTPTVEDDVFVGKLPTFEKRCETPAGTSRGPSPVTLASQDALPIAVAFTESVNAYFKGADPSKCIVKITGDMTLSFPSG-IIKIFTSSPSPAVLSFKLLNASRLEQIMPNQQLLHSDSSQSDTNTKDFWMNMPALTSFLRKSSEQNPAASYYNVDILKYQVCSNGIQSTPLNLVVYWKCSRSTTDLRVDYRYNPEAMQPPAPLTNVQVLVPVNGGVMNMQSLPNAIWNAEQNKSLWKLSDISDKSENEGSGSLRAKFELSEGPSIPATLAVQFFSEGSSLSGVDMELAGSGYRLSLNKKRFATGRYMADC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K285-1", "uniprot_id": "FCHO1_MOUSE", "id": "Q8K285-1", "name": "F-BAR domain only protein 1", "aln": "---MSYFGEHFWG---DKNHGFEVLYHCVKQGPVATKELADFIRERANIEETYSKAMAKLS-------KLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKD-VLRYGEEQLKTHKKCKEEVLGTVDAVQMLSGVGQLLPKSRENYLSRCMDLE------------RLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARADFEIKMLDSALRFQAMEEAHLQHMKALLGSYAHSVEDTHVQIGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKPGPLDFDAYSSAALQE--------AMKRLRGAKAFRLPGLSRRE----PRASVDFLESDS----------------GVPPEVDDEGFTVRPDISQNNGAEPPRFSSSDSDFDDEEPRKFYVHIKPAPTRAVACSSEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTSGKPQRPRSAPRTGSCAEKPLASEEPLSKSLFGPPLESAFDHDDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPESWVPRPGTPQSPPTCRAQHPEPR---------GLMPRAPSPGPWGPEG--GADSL-TPADPT-REGLAATLRRPRSRKVSCPLTRSNGDLCRSLSPSPLGSSAPTIPPDRPSFSTQMG--------------HGISRGPSPVVLGSQDALPVATAFTEYVHAYFRGHSPS-CLARVTGELTMTFPAG-IVRVFSGTPPPPVLSFRLVNTAPVEHFQPNADLIFSDPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPESVPLQMSAHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEKRFTWKLPDVC---EAGGSGHLSASWQPQSGPSTPSPVAAQFTSEGATLSGLDLELLGGGYRMSLVKRRFATGMYLVSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIM5-1", "uniprot_id": "D3ZIM5_RAT", "id": "D3ZIM5-1", "name": "", "aln": "---MSYFGEHFWG---DKNHGFEVLYHCVKQGPVATKELADFIRERASIEETYSKAMAKLS-------KLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKD-VLRYGEEQLKTHKKCKEEVQGTVDAVQMLAGVGQLLPKSRENYLSRCMDLE------------RLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARADFEIKMLDSALRFQAMEEAHLQHMKTLLGSYAHSVEDTHVQIGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKPGPLDFDAYSSAALQEGNYPLLSTAMKRLRGAKAFRLPGLSRRE----PRASVDFPESGS----------------GVPPEVDEEGFTVRPDTSQNSEAEPPRFSSSDSDFDDEEPRKFYVRIKPAPARTMACSSEAAAAQLRATAGSLILPPGPGGTMKRLSSRDTSGKPQRPRSAPRS-SCTEKPLASEEPLSKSLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSLAAPGPSPESWVPRPGTPQSPPTCRAQHQEAR---------DPVPRVPSPGPWGPEAGAGADSL-TLADPT-REGLAATLRRPRSRKVSCPLTRSSGDLCRSLSPSPLGSSAPTIPPDRPSFSAQMG--------------HGVSRGPSPVVLGSQDTLPVATAFTEYVYAFFRGHNPS-CLARVTGELTMTFPAG-IVRVFSGTPPPPVLSFRLVHTSPIEHLQPNADLIFSDPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPKSMPLQMSAHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEKRFTWKLPDVR---EAGGSGHLSASWQPQSGPSTPSPVTAQFTSEGATLSGLDLELLGGGYRMSLVKRRFT-GMYLTSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14526-1", "uniprot_id": "FCHO1_HUMAN", "id": "O14526-1", "name": "F-BAR domain only protein 1", "aln": "---MSYFGEHFWG---EKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLS-------KLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKD-VLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------------RLRRESTSQKEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQE--------AMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDS----------------GTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAER-LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTG--------------HGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGELTMTFPAG-IVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVS---EAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43556-1", "uniprot_id": "RGD2_YEAST", "id": "P43556-1", "name": "Rho-GTPase-activating protein RGD2", "aln": "---MLSFCDYFWS--EDLVSGLDVLFDRLYHGCEQCDLFIQLFASRMQFEVSHGRQLFGIEAGMDNLKAVQEDEDEGVTVSRALRGILQEMSQEGTHHLTIASNIESLVLQPFSKWCIEHRERIQYSEKTLLTNVNNFRKSKKYVGKLEKEYFNKCRQLEEFKRTHFNEDE----LANAMKSLKIQNKYEEDVAREKDHRFFNRIAGIDFDYKTMKETLQLLLTKLPKTDYKLPLISYSLSNTNNGGEITKFLLDHMSLKDIDQAETFGQDLLNLGFLKYCNGVGNTFVNSKKFQYQWKNTAYMFANVPMPGSEEPTTGESLISRFNNWDGSSAKEIIQSKIG-------------------------NDQGAAKIQAPHISDNERTLFRMMDALAASDKKYYQECFKMDALRCSVEELLIDHLSFMEKCESDRLNAIKKATLDFCSTLGNKISSLRLCIDKMLTLEN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIDPTADLLQLLVKYKTGSFKPQAIVYNNYYNPGSFQNFGVDLETRCRLDKKVVPLIISSIFSYMDKIYPDLPNDKVRTSIWTDSVKLSLTHQLRNLLNKQQFHNEGEIFDILSTSKLEPSTIASVVKIYLLELPDPLIPNDVSDILRVLYLDYPPLVETALQNSTSSPENQQDDDNEEGFDTKRIRGLYTTLSSLSKPHIATLDAITTHFYRLIKILKMGENGNEVADEFTVSISQEFANCIIQSKITDDNEIGFKIFYDLLTHKKQIFHELKRQNSKN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** * : . : .* . . ::. * * :.: : : . :. : . .: . *: : :.. . . : .: : : : . : : : : . : : : : ::. : . .. :: ", "identical_positions": 8, "similar_positions": 54, "identity": "0.83%" }, { "cls_id": "homologset.agr.SGD:S000001848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M9Y2-1", "uniprot_id": "A0ABK0M9Y2_RAT", "id": "A0ABK0M9Y2-1", "name": "", "aln": "MARGQGRGDAKASPGEGETGGAGLGPPSEGRGQGGLRRGWRLWGGGVATADYAAGGQERAGLHGGPRSLPRRLGIGTARERHACALRPVTHSGMDSGSLAAERPKRTPGRQRLLSSGCGVPVRPG---------VSTLPGGRSWLRPRGRTAR-----ASRLLLLLLVPSPRLAATA----PRRTLA--ERSRPGLVIPAAALGAGR-------NALGRLRLGARRVAALVSSRRELSLSARCHQLEPRKGNLPTSVSRQLYFDTHALVCLLEANGFTIQQAEIIVSALVKITETNMDIIYKDMVSKMQQEITLQQIISKIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVTKVRTDTKLNFNLEKSRVKELYSLNEKKMLELRTEIVSLHAQQDRALTQTDRKIETEVAGLKTMLEAHKLDTIKYLAGSVFTCLTVALGFYRLWI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXD6-1", "uniprot_id": "MCUR1_MOUSE", "id": "Q9CXD6-1", "name": "Mitochondrial calcium uniporter regulator 1", "aln": "---------------------------------------------------------------------------------------------MDSGSVAAERPRRTPSRQRLPSSGCGVPARPG---------VSTLPGGRSWLRPRGRAAR-----ASPLLFLLLVPSPRLAATATATAPRRTLA--ERSRPGLVLPAAALGAGR-------NALGRLRLGARRVAALASSRRELSLSAKCHQLEHRKENLPLSVSRQLYFDTHALVCLLEANGFTIQQAEIIVSALVKITETNMNIIYKDMVSKMQQEIALQQVLSKIANVKKDMVILEKSEFSALRAENEKIKLELHQLKQQVMDEVTKVRTDTKLNFNLEKSRVKELYSLNEKKMLELRTEIVSLHAQQDRALTQTDRKIETEVAGLKTMLEAHKLDTIKYLAGSVFTCLTVALGFYRLWI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AQ8-1", "uniprot_id": "MCUR1_HUMAN", "id": "Q96AQ8-1", "name": "Mitochondrial calcium uniporter regulator 1", "aln": "---------------------------------------------------------------------------------------------MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAA----PRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C3X2-1", "uniprot_id": "CC90B_MOUSE", "id": "Q8C3X2-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------MRSRWIWR---------------------------FLRPDGGGIR-------------WTSTP----------------------HGRLSP--------------------------------ALRRGFLTTTTKSDYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAQTIVSVLSTLSNVSLDTIYKEMVTKAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLTNETSRIRADNKLDINLERSRVTDMFTDQEKQLIEATNEFAKKDTQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGFYRFWKEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V897-1", "uniprot_id": "CC90B_RAT", "id": "Q4V897-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------MRNRWIWR---------------------------FLRPECSGIR-------------WISSP----------------------HGRLSP--------------------------------ALRRGFLTTTTKSDYDRRPVEITPLEQRKLTFDTHALVQDLETHGFDKGQAQTIVSVLSTLSNVSLDTVYKEMVTKAQQEITIQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLINETSRIRADNRLDINLERSRVTDMFTDQEKQLMEATNEFTKKDMQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGFYRFWKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZT6-1", "uniprot_id": "CC90B_HUMAN", "id": "Q9GZT6-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------MNSRQAWR---------------------------LFLSQGRGDR-------------WVSRP----------------------RGHFSP--------------------------------ALRREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFWK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43557-1", "uniprot_id": "FMP32_YEAST", "id": "P43557-1", "name": "Protein FMP32, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRIVGLPARRCFHRTSFLLGSDFETVHIPNTNHFKDLLIENGKFQEDQATTIVEIMTDAIRGGVNHVSQDLAKREKLTQLSYQQRVDFAKLRDQLLSADRSEFHNIQNEYESVKNDLEKLRNKLREEITKTNAGFKLDLSLEKGRIREESS------------------HHDLQIKEIDTKIEQEVTNMKMQIDSVKTQVMQWLIGVCTGTFALVLAYMRLLT--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . .: . :: .* :* * ** **. : . .:: : :::..: : * .: ::.::: ::*** :: * *.:* :*.:::::: .* : .:. :*::.**:.*: : : : . :.: . **: *::.:* ::: * : :::* . :::.*.: *: ", "identical_positions": 29, "similar_positions": 85, "identity": "6.33%" }, { "cls_id": "homologset.agr.SGD:S000001849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35621-1", "uniprot_id": "PMM1_MOUSE", "id": "O35621-1", "name": "Phosphomannomutase 1", "aln": "MAVAVEGARRKERILCLFDVDGTLTPARQKIDPEVSAFLQ-KLRSRVQIGVVGGSDYSKIAEQLGEGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNVSPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDED-SFDIIHFFGNETSPGGNDFEIYADPRTVGHSVVSPQDTVQRCRELFFPETAHEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92871-1", "uniprot_id": "PMM1_HUMAN", "id": "Q92871-1", "name": "Phosphomannomutase 1", "aln": "MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQ-KLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQD-SFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2M7-1", "uniprot_id": "PMM2_MOUSE", "id": "Q9Z2M7-1", "name": "Phosphomannomutase 2", "aln": "MAT-----------LCLFDMDGTLTAPRQKITEEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQLG--NDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEDVIQDLINYCLSYIANIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISIDVFPEGWDKRYCLRHLEHA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEGLFP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F1X7-1", "uniprot_id": "F7F1X7_RAT", "id": "F7F1X7-1", "name": "Phosphomannomutase", "aln": "MAT-----------LCLFDMDGTLTAPRQKITKEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQLG--NDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEAVIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHLEQA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEELFP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15305-1", "uniprot_id": "PMM2_HUMAN", "id": "O15305-1", "name": "Phosphomannomutase 2", "aln": "MAAPGP-------ALCLFDVDGTLTAPRQKITKEMDDFLQ-KLRQKIKIGVVGGSDFEKVQEQLG--NDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVEND-GYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07283-1", "uniprot_id": "PMM_YEAST", "id": "P07283-1", "name": "Phosphomannomutase", "aln": "MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLA-KLRNKCCIGFVGGSDLSKQLEQLG--PNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKD-GFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTZ6-1", "uniprot_id": "PMM_DROME", "id": "Q9VTZ6-1", "name": "Phosphomannomutase", "aln": "MTTAALK---RDEILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLN-GRKILNEFDFIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ***:***** .* : *. : ::: : **.***** * ***. .:::::*: *.*** . . *: : *.: *** : : : * *:: : :* :****:******:*:.****..: *** * . * :.::* *:: *: **.. .* :* ** **:**** **** *** :: :. *:***::* ****.**: * **:.: * :*.** : :: ", "identical_positions": 96, "similar_positions": 71, "identity": "36.36%" }, { "cls_id": "homologset.agr.SGD:S000001850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q05-1", "uniprot_id": "OTU1_RAT", "id": "Q32Q05-1", "name": "Ubiquitin thioesterase OTU1", "aln": "MFGGAKGGHFGVPPA-GCSGAVSQAAAGTKAGPAGGRPA----DTMWRLRCKAKGGTHVLQGLSNRTRLRELQGQIAAITGIAPGSQRILVGYPPECLDLSDRD-----ITLGDLPIQSGDMLIVEEDQTRPKASPAFS------------------------------KHGAPSYVRETLP-----------VLTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDLYSEAILGKTNEEYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRKRQFTDVNRFTLRCMLCQKGLTGQAEARDHARETGHTNFGEV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB27-1", "uniprot_id": "OTU1_MOUSE", "id": "Q8CB27-1", "name": "Ubiquitin thioesterase OTU1", "aln": "MFGGAKGGHFGVPPA-GYSGAVPQSEAGTKAGPAGGRPA----DTMWRVRCKAKGGTHLLQGLSSRTRLRELQGQIAAITGIAPGSQRILVGYPPECLDLSDRD-----ITLGDLPIQSGDMLIVEEDQTRPKASPAFS------------------------------KYGAPSYVREALP-----------VLTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPVLYSEAILGKTNEDYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRKRQFTDVNRFTLRCMICQKGLTGQAEARDHARETGHTNFGEV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVQ6-1", "uniprot_id": "OTU1_HUMAN", "id": "Q5VVQ6-1", "name": "Ubiquitin thioesterase OTU1", "aln": "MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVLQGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGD-----TILEDLPIQSGDMLIIEEDQTRPRSSPAFT------------------------------KRGASSYVRETLP-----------VLTRTVVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q567B1-1", "uniprot_id": "OTU1_DANRE", "id": "Q567B1-1", "name": "Ubiquitin thioesterase OTU1", "aln": "---------------------------------------------MLRLRCKAKNGTHLMQGLTHQSCVQELKDKIEELTGIPCDVQKIMVGYPPSSLDLRNGE-----AHLKDYPIKSGDTLIVEEEKNKPKPPVQPT------------------------------VTKGPSF--EVTP-----------VVERRVVPADNSCLFTSVNYVMEGGVYDPACASEMRGLIAQIVASDPTAYSEAVLGKTNEEYCTWIRRDDTWGGAIEVSILSKFYQCEICVVDTQTVRVDRFGEDAGYTKRVLLIYDGIHYDPLQKVLPGSDVPAQTVFSTVDDVILAQALELADEARRKRQFTDVNRFALRCMVCQTGLVGQKEAREHAKETGHTNFGEV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRJ9-1", "uniprot_id": "OTU1_DROME", "id": "Q9VRJ9-1", "name": "Ubiquitin thioesterase Otu1", "aln": "MTG------------------------------------------SFSVKLKSKKGQFIVNDLNEHTTLGELKTKIVQATDIEATQLHVLVGYPPKPLDLSQQQE---QRALKAVGINSGETLIVEEKAAPAPAAPVPGGTTVEDDEALARRLQAEEEAQLLQETAGGPVAQAADYQLPVAPTESGPNGDFNGILLKKVVPADNSCLFTSIRFVLNGKVDNEGSE-MMRHIIAQEVAADPQSYNDAVLGKSNAEYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGEDKNFGLRVFLLFDGIHYDPLYMETS-PSAAPATIFPVEELGVYQQAEQLANEAQSSRQYTNVDKFTLRCMQCDVRLVGQVQAQEHAKQTGHKNFGEI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43558-1", "uniprot_id": "OTU1_YEAST", "id": "P43558-1", "name": "Ubiquitin thioesterase OTU1", "aln": "------------------------------------------------MKLKVTG-----AGINQVVTLKQDATLNDLIEHINVDVKTMRFGYPPQRINLQGEDASLGQTQLDELGINSGEKITIESSDSNESFSLPPP-------------------------------QPKPKRVLKSTEMSIGGSGE--NVLSVHPVLDDNSCLFHAIAY----GIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDK-FDNYILILFNGIHYDSLTMNEFKTVFNKN---QPESDDVLTAALQLASNLKQTGYSFNTHKAQIKCNTCQMTFVGEREVARHAESTGHVDFGQNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . .:. : : * : .****. ::* : * *:**: : :*.. . .. :: * ****** :: : : . . :* :::: * :* :.:*:*.*.* :*. ** : ::******:.*:*. * *** : . :::*.** : ::::::*****.* . . : * :**.: : :..: ::* *: :.*: :. **..*** :**: ", "identical_positions": 63, "similar_positions": 89, "identity": "15.95%" }, { "cls_id": "homologset.agr.SGD:S000001852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEF1-1", "uniprot_id": "ASTRA_MOUSE", "id": "Q8VEF1-1", "name": "Protein Aster-A", "aln": "------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR--------------------------------------------------------------------LQLLPPIRPPPASEPEPG-------TMVEKGSDSSS-------------------------------------------------------EKSG----------VSGTLSTQSLGS--------------------------------RNFIRNSK---------------KMQSWYSMLCPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEK-----------HFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLG--------SPKEVGDVIALSDISPSGAAD------------------------------------------------------------------------------------HSQEPSPVGSRRGRVTPNLSR--ASSDADHGAEE-DKEEQTDG-LDASSSQTVTPVAEPLSSEPT---------------------PPDGPTSS---LGPLDLLSREELLTDTSNSSSSTGEEGDLAALLPDL---SGRLLINSVFHMGAERLQQMLFSD--SPFLQGFLQQRKFTDVTLSP--WSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLDRELAKAEKLSLEEG---------------------------GKDTRGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALNALLFYRLWSLER--TAHTFESWHSLALAKG-KFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVPDPPLDTQPQPDDSFP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR56-1", "uniprot_id": "ASTRA_RAT", "id": "Q3KR56-1", "name": "Protein Aster-A", "aln": "------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR--------------------------------------------------------------------LQLLPPSRPPSAPEPEPG-------TMVEKGSDSSS-------------------------------------------------------EKSG----------VSGTLSTQSLGS--------------------------------RNFIRNSK---------------KMQSWYSMLCPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEK-----------HFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLG--------SPKEVGDVIALSDISPSGAAD------------------------------------------------------------------------------------RSQEPSPVGSRCGRVTPNLSR--ASSDADHGAEE-DKEDQTDSQLDASSSQTVTPVAEPLSAEPA---------------------PPDGPTSN---LGPLDLLSREELLTDTSNSSSSTGEEGDLAALLPDL---SGRLLINSVFHVGAERLQQMLFSD--SPFLQGFLQQRKFTDVTLSP--WSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDRELAKAEKVSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALNALLFYRLWSLER--TAHTFESWHSLALAKG-KFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVPDPPLDTQPHPDDSFP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CP6-1", "uniprot_id": "ASTRA_HUMAN", "id": "Q96CP6-1", "name": "Protein Aster-A", "aln": "------------------------------------------------MFDTTP-------------------HSGRSTPSSSPSLRKR--------------------------------------------------------------------LQLLPPSRPP--PEPEPG-------TMVEKGSDSSS-------------------------------------------------------EKGG----------VPGTPSTQSLGS--------------------------------RNFIRNSK---------------KMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEK-----------HFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSP--LQLNGLG--------TPKEVGDVIALSDITSSGAAD------------------------------------------------------------------------------------RSQEPSPVGSRRGHVTPNLSR--ASSDADHGAEE-DKEEQVDSQPDASSSQTVTPVAEPPSTEPT---------------------QPDGPTT----LGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDL---SGRLLINSVFHVGAERLQQMLFSD--SPFLQGFLQQCKFTDVTLSP--WSGDSKCHQR-RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRA-HGD------GPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIVICVSLIILIALNVLLFYRLWSLER--TAHTFESWHSLALAKG-KFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPDDSFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NZU2-1", "uniprot_id": "A0A8M9NZU2_DANRE", "id": "A0A8M9NZU2-1", "name": "", "aln": "-----------------------------------------MYEGLLVMAMTTPPEILIAEPISIPILNILPPSSDTESWSRSPSPRAHRYRSRSREKRKAKAQQEDKSGAKHCDKRKG----------ELERSPSHASASSSMVCNVDDEEQGNPCVLLLPPSRSWSRSSSLSRRSRWSIRSLLNKDSDCDSS-------------------STASNSPRSTPGSSPSLRRRVLG--GRASEGETAGEKSGGGSDSPLPPTPSSSTSSYPLAA--------------------------------RHFTRNAK---------------KMQSWYNVLSPTYKQRNEDFRKLFKKLPDTERLIVDYSCALQKDILLQGRLYLSENWLCFYSNIFRWETTITILLKDVTNLTKEKTAKLIPNAIQISTENEK-----------HFFTSFGARDRSYMMIFRLWQNALMDKTLSPKELWHIVHQCYGTELGLTSEDDDYVSPTAEHMNGLL--------PGEEPVSVTDLLDLGSVPVAP------------------------------------------------------------------------------------ASSSPPSSASVLPCASGSSPP--SSSSSSQPVEVPSIRASIDPEPSPPSSQSSLPPVTNTGAVPASVILKEGGDSQSESANHSLQSPPSIPHNLGN-LSSLDMTNDEDLPTDPSNSSD-TQEESEVESFCADL---NGRLHINTVVRMGVDKLHDLLFSD--THFIQHLFSQRHFTDLSVHE--WQQDSSSGSSSRVLSYTIAINNPLGPKTAPVVETQTLHKSSSRSECYVVDSEVITSGIPYQDYFYTVHRYCLTSVNKHKSRLRVSSDICYRKQPWSLVKALIEKNTWSGIEEYYRHLEMEVCKLETLLQTEVTVVS------------------AGEMPSPDSTKTPPGLRRRKRTCPRRAGERDRDREAAGGGERGDRITDERDRREAGGQYMKLGERWRAGGGSNNNSISTILLI----------------------------------------------------------------------------------------------------------VSFI----LVVLVALNMMLFYKLWALER--AAHTLETWHSYSLTDS-PLPQSAGEWAQVLQLQRQFHQAQMNKWQQILQSSVTLLDQMKQSLEKLHRGMIPPEGQQESDPEPDTLADQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U406-1", "uniprot_id": "A0AB32U406_DANRE", "id": "A0AB32U406-1", "name": "", "aln": "-----------------------------------------MSETLQLPALQIQGPE---CNGSEVDPN--------LSSSSSPALRRKRFKMRRMKNVMSEKEQLEK----EQLQRSGSKEYLQLPSIEITPSSDEDAAWSSCSTPSASPQRRRFLLRKWLRGGEKKEHGSESSSQQSS----LQSSHEEESTRYLSPNTRED---------STASNSNRSTPACSPVLRKRSRSPTPQSPEGENMVEKGSDHS-SDKSPSTPEPAVQRTYSQSL---------------------------HTTRTGGKNSKSHKRLSKYDGLNLIKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDVCSMTKEKTARLIPNAIQLCTDNEK-----------HFFTSFGARDRTYMMMFRLWQNALLDKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPD-DDFNTMGCCPSPWCRYCEEIPAEDNEAN-DNCNKTP---------------------------------------------------------------------------------DAKMDISPQLHRKVFPNSSLNSTD---STDAPLNFDVPPVEDFTNCIPE-DLLPLTLPDNKLSETGGS----------------------AHVPAPS----PSLDFNDNEDLPTELSDSSETHDEAGEVQAFQEDL---NGKLYINEVYKFSVDKLHDILFTE--SQFMREFLEQRRFSDVVYHP--WRKEDTGNQT-REIMYTISLSNPLAPKTATVTETQTLHKASQVSECYIIDAEVIAHDVPYHDYFYTLNRYMLTRVARNKCRLRVSAELRYRKQPWGLVKGFIERNFWSGLDEYFRYLELELNKVQLV-LSE--------------------------QSPKSKALRTATVRRRKRPLTHMRPQHMDEALSPVTTPEDEKSVIQRIKHVAGSTQTRHMPDHASEGLALYS-VSKLLLI----------------------------------------------------------------------------------------------------------IS----SVLVLLVFLNLMLFYKLWMLEY--TAQSLASWQGLRSHES-KLPQTQIEWAQLLESQQRYHESELEKWREIIKSSVLLLDEMRESLMKLQKGIGLRDYDSDSEERRSHYH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YTR6-1", "uniprot_id": "A0A8M6YTR6_DANRE", "id": "A0A8M6YTR6-1", "name": "", "aln": "-----------------------------------------MTDTLRPPSLQVHVPRDEPSHGEEEGGSGGGQDSLVWSSSSTPTLRRRRFKMRRMKKLPSERERLENGLLWHPASRSASKEYLQLPSIEITPSSDEDAAWSNSSTPSASPRRKRFLLRKWLKVRERKEQGSESSSQQSSQQSSQQSSHDDDSSRFLTPFIREDRADSGPDKCSTASNSNRSSPACSPVLRKRCRSPILQSAEPDAMVEKGSEQSDASKSPSTPEQLVTRTFSG-----------------------------QSTRSGGKNSKSHKRLSKYDRINLIKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDTEKSLKSQKLQLKSHFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPD-DDFNTMG--------YCEEIPAEENEVSNDNSSKSSSE------------------------------------------------------------------------------NKPDNNSSPPTHKRSITHSTITSTTPPSSTDTPLSFDIS-AEEYTDCLADGDLLPLPLLAEERNSEPAS----------------------PVGSVLP----PALDFNDNEDIPTELSDSSETHDEGDEVQAFHEDL---NGRQYINEIYKFSVDKLYSVLFTE--SQFMTDFMEQRRFTDVVYHP--WKKEGAGNQT-RDIMYTISLTNPLAPKTAAVTETQTLYKASQENECYIIDAEVITHDVPYHDYFYTLNRYMLTRVAKNKCRLRVSTELRYRKQPWGLVKGFIEKNFWSGLDENFKSLELELAKMEDA-MMESH-----------------------RLSPKSKALKNSTLRRRKRQLAHLRTGHLDETLSPVTTPTDEE-VIHRIKHVAGSTQTRHIPEHTTGGGIFCN-LSKPLLI----------------------------------------------------------------------------------------------------------ISFVICISLVLLVFLNVMLFYKLWMLEY--SAQSLTSWQGLRLHESSKLPQTQMEWAQLLESQQRYHDAELQKWREIIKSSVLLLDQMKDSLLSLQKGVGLREYNSESDQKRSRYY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LIC7-1", "uniprot_id": "A0ABK0LIC7_RAT", "id": "A0ABK0LIC7-1", "name": "", "aln": "------------------------------------MPAANMMENLQLPALQVPEPQGAPEGSA------------VWSSSSTPTLRRRRFKMRRMKNVQEQSLEAGLVAPDLPGVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSASPRRKRFLLRKWLRVRERKEC-SESSSQQSS----QQSSHDDDSSRFLSPRVREE---------STASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHS-SDKSPSTPEQGVQRSCSS-----------------------------QSGRSGGKNSK---------------KSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK-----------HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPD-DDFNTMG--------YCEEIPIEENEVN-DSSSKSS--------------------------------------------------------------------------------IETKPDASPQLPKKSITNSTLTSTG---SSEAPVSFDGLPLEEEV--MEGDGSLEKELAIDNIIGEKIE----------------------IMAPVTS----PSLDFNDNEDIPTELSDSSDTHDEG-EVQAFYEDL---SGRQYVNEVFNFSVDKLYDLLFTT--SPFLRDFMEQRRFSDIIFHP--WKKEENGNQS-RVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKTESTYLAEIH-----------------------RQSPKEKTNKSSAVRRRKRPHAHLRVPHLEEVMSPVTTPTDED-VGHRIKHVAGSTQTRHIPEDTPDGFHLQS-VSKLLLV----------------------------------------------------------------------------------------------------------ISCVICFSLVLLVILNMMLFYKLWMLEY--TTQTLTAWQGLRLQER--LPQSQTEWAQLLESQQKYHDTELQRWREIIKSSVMLLDQMKDSLINLQNGIRSRDYTAESDEKRNRYH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TI0-1", "uniprot_id": "ASTRB_MOUSE", "id": "Q80TI0-1", "name": "Protein Aster-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGFKLS---------CTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHS-SDKSPSTPEQGVQRSCSS-----------------------------QSGRSGGKNSK---------------KSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK-----------HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPD-DDFNTMG--------YCEEIPIEENEVN-DSSSKSS--------------------------------------------------------------------------------IETKPDASPQLPKKSITNSTLTSTG---SSEAPVSFDGLPLEEEV--MEGDGSLEKELAIDNIIGEKIE----------------------IMAPVTS----PSLDFNDNEDIPTELSDSSDTHDEG-EVQAFYEDL---SGRQYVNEVFNFSVDKLYDLLFTN--SPFLRDFMEQRRFSDIIFHP--WKKEENGNQS-RVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKTESTYLAEIH-----------------------RQSPKEKASKSSAVRRRKRPHAHLRVPHLEEVMSPVTTPTDED-VGHRIKHVAGSTQTRHIPEDTPDGFHLQS-VSKLLLV----------------------------------------------------------------------------------------------------------ISCVICFSLVLLVVLNMMLFYKLWMLEY--TTQTLTAWQGLRLQER--LPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVLLLDQMKDSLINLQNGIRSRDYTAESDEKRNRYH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR37-1", "uniprot_id": "ASTRB_HUMAN", "id": "Q3KR37-1", "name": "Protein Aster-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGFKLS---------CTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHS-SDKSPSTPEQGVQRSCSS-----------------------------QSGRSGGKNSK---------------KSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEK-----------HFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPD-DDFNTMG--------YCEEIPVEENEVN-DSSSKSS--------------------------------------------------------------------------------IETKPDASPQLPKKSITNSTLTSTG---SSEAPVSFDGLPLEEEA--LEGDGSLEKELAIDNIMGEKIE----------------------MIAPVNS----PSLDFNDNEDIPTELSDSSDTHDEG-EVQAFYEDL---SGRQYVNEVFNFSVDKLYDLLFTN--SPFQRDFMEQRRFSDIIFHP--WKKEENGNQS-RVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKTESTYLAEMH-----------------------RQSPKEKASKTTTVRRRKRPHAHLRVPHLEEVMSPVTTPTDED-VGHRIKHVAGSTQTRHIPEDTPNGFHLQS-VSKLLLV----------------------------------------------------------------------------------------------------------ISCVICFSLVLLVILNMMLFYKLWMLEY--TTQTLTAWQGLRLQER--LPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSLINLQNGIRSRDYTSESEEKRNRYH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CI52-1", "uniprot_id": "ASTRC_MOUSE", "id": "Q8CI52-1", "name": "Protein Aster-C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGALTAR----------QIVNEGDSS------------------------------------------------------LATELQ---EEPEESPGPVVDENIVSAK---------------------------KQGQSTHNWSG-----------------DWSFWISSSTYKDRNEEYRQQFTHLPDSEKLIADYACALQKDILVQGRLYLSEKWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEK-----------FFFTSFGARDRSYLIIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMEHL-LSVEENVQPRS------------PGRSSVDDAGERDEKF-------------------------------------------------------------------------------------SKAVSFTQESVSRASETEPL--DGNSPKRGL-------GKEDSQSERNVRKSPSLASEK---------------------------RISRAPS----KSLDLNKNEYLSLD---KSSTSDSVDEENIPEKDL---QGRLYINRVFHISAERMFELLFTS--SHFMQRFANSRNIIDVVSTP--WTVESGGNQL-RTMTYTIVLSNPLTGKYTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLESYFKKLESDLLMEESVLSQSI-----------------------------EDAGKHSSLRRRRRTLNRTAEPVPK-----LSSQRSSTDLGFEAKVDVT--GKRKTVDSYD--------TALIVV-----------------------------------------------------------------------------------------------------------MSIFL----LLLVLLNVTLFLKLSKIEH--ATQSFYQ---LHLQGEKSLNLVSDRFSRTENIQK--NKDQAHRLKGVLQDSIVMLEQLKSSLIMLQKTFDLLNKNKSGVAVES-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A135-1", "uniprot_id": "D4A135_RAT", "id": "D4A135-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MRTQAVLWRSPSREEPSTPQTNSQCQADS----------PIVNDGDSS------------------------------------------------------LATELQ---GELEENSSPAVDESIVSAK---------------------------KQGPSTHNWSG-----------------DWSFWISSSTYKDRNEEYRQQFTHLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEK-----------FFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMEHLSLSIEENVQPRS------------PGRSSVDDSGERDEKF-------------------------------------------------------------------------------------SKAISLTHESVSRASETESL--DGNSPERGL-------GKEGSQSERHVRKSPSLASEK---------------------------KLGRVPS----KTLDLNKNEYLSLD---KSSTSDSVDEENIPEKDL---QGRLYINRVFHISAERMFELLFTS--SHFMQRFTNSRNIIDVVSTP--WTVESGGDQL-RTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLENYFKQLESDLLMEESVLSQPM-----------------------------EDAGKLSSLRRRRRTLNRTAEPVPK-----LPSQRSPTDLGFEAKDDIT--GKRKAVDSCD--------TALIVV-----------------------------------------------------------------------------------------------------------MSVFL----LLLVLLNVTLFLKLSKIEH--ATQSFYQ---LHLQGEKSLNLVSDRLSRTENIQK--NKDQAHRLKGVLQDSIVMLEQLKSSLIMLQKTFDLLNKNKSGVVVES-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYS0-1", "uniprot_id": "ASTRC_HUMAN", "id": "Q8IYS0-1", "name": "Protein Aster-C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGAPTVR----------QVMNEGDSS------------------------------------------------------LATDLQ---EDVEENPSPTVEENNVVVK---------------------------KQGPNLHNWSG-----------------DWSFWISSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIVTESEK-----------FFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIED-VQPRS------------PGRSSLDDSGERDEKL-------------------------------------------------------------------------------------SKSISFTSESISRVSETESF--DGNSSKGGL-------GKEESQNEKQTKKSLLPTLEK---------------------------KLTRVPS----KSLDLNKNEYLSLD---KSSTSDSVDEENVPEKDL---HGRLFINRIFHISADRMFELLFTS--SRFMQKFASSRNIIDVVSTP--WTAELGGDQL-RTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAI-----------------------------EDPGKLTGLRRRRRTFNRTAETVPK-----LSSQHSSGDVGLGAKGDIT--GKKKEMENYN--------VTLIVV-----------------------------------------------------------------------------------------------------------MSIFV----LLLVLLNVTLFLKLSKIEH--AAQSFYR---LRLQEEKSLNLASDMVSRAETIQK--NKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAVES-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q853-1", "uniprot_id": "A0A8M9Q853_DANRE", "id": "A0A8M9Q853-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MTETPKPLMGNELAQENG----------QSGEVRGSS------------------------------------------------------EEQEMKGITQTPKQPMGKATDGKNPEEQ---------------------------EALEVTVQFTAA---------------PQSTDSLYYTSYKQRSDEFRKLFKEVPEHEKLVVDYTCALQKDILLQGRIYFTENCLCFYSHVFR-GTKIMVNMKDIISVSKEKTAKWIPNAIQISTNSEK-----------LFFSSFSTREKSYQSIFRLWQNVLMEKKLTKLELLQMVRQHYGNDLGLSHDEMESFQTSVDTITPTLP------------SLNMRGEDYTGRPERP-------------------------------------------------------------------------------------TSLRLPHGELNSYEASTPQG--DDTQSSVGLHSVLSANGGDDSLSTPSHQLSPNLSLNRSGS-----------------------ERVSKRSS----FSLDLNANEDQLSDNS-RSDSLEEVEERETASPVS---QGRLFVNRVFHISAEKMFNLLFSD--SSFTRRFMDIRKITGITATP--WKKEASGCMK-RTLNYTITINNPLVGKFSTATETQTLYKESREGQYYMIDSEVYTHDVPYHDYFYTQNRYCIIRNSKHKCRLRIYTDVKYKKQPWGLVKSFITKNSWSGLEDYFRHLEAELLDEEAELTQGS-----------------------------GDAGKTGALRRRRRTYSRTLQEHMK-----PAKAQYSTDSEQQRTGTMGPMDIKNTPHRWN--------ITSVVFG----------------------------------------------------------------------------------------------------------MSLIL----FVLVVLNLGLFFKLWAMED--VAHRMYLNTKHRMKERVESSLPPDLGPRHGMPHR--SQEEVHLLRAVLQDSINLLEQLRSSLLVLQQNFQVYNRTSSPL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "R9PY62-1", "uniprot_id": "R9PY62_DROME", "id": "R9PY62-1", "name": "", "aln": "MPKEDIKKPPRKTLNVDAKKAKRKKMIKDSDKINPTTSSVNITVTTAESSSSCKNPANANMIPETTQPDQLQSQTQTQAQLQPQSQSPSQCQQAQENPEHLQQQSQPEEELQAEAPGSNAGDRRDSITEEITITSTTNSSQSTKLLTIQEAAGSFEQSSVSAVSTSSKQIASTTAGGSPPAAAAPGANEFNGSVLRLTQAATSTSPGSISSAGNTATLGAAPSINIVSSESTRDQTQQPQSVDPNGVAAPGDSPSSRKSSTSSKGKASQAKLSTSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTSNEKPAKTSRLSERAKKKSWYNVIYPNYKSRAEDFKKLFKDVPNDERLIVDYSCALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSGKDK-----------YFFATFTSRDKSFLMLFRVWQNTLMNKQFSPQEIWQHVHTCYGDELGLTTDDEDYIDPTLNKTNEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSGGGVRASAPRKSKTKYFFNSSKSSANASASGSDNNKTRESSRKLNKKMKQNAKELTLSSVKPTELSVSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSGSLSGSNTAAASGSGSDKMSAEKKVSTASNSAAVAAAEAAQSLASASSGSGSLESKMEMKRKLGKMHRQREEGKNAAESVPTDVSDSSDSEENNLPFVPTTECTSTHEGRQIVHTILPINVDTLFNLLFSK--SKFITDFHAMRKSTDLVLGE--WTKNEEGLQV-RTVNVTVQLAASVGPKTSKVTEYQTQRECSKPGELYSIDVNSVNAGIPYAESFSVLIHFCLARTVDDHTMLSIHTQIKYKKSIWGVVKGFIEKNTWAGLEDFFGAQLHALQSETCIPPAKGKGRRPRRGMNQQSATSTSTTSITTGALHTATSTDNDSIQESRHPHQQDQHQHQHLHMHHHHHHHHGSQHHHHDARHSHHHHHQPLLPHHQQQHPHHWHHRKALLQSGRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVGAAAGHPLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGDGQPLASGQGSQGHRLRHKGLWLLVILLLCLMLALNVILLLKLWRLEERIDVDLNRRARMPSLAALSELPSTNQEWLELLRDQEMAHENELHKWQQVLQTAIELLKKVSIVCEKITNDSHLRQSIESMSMAGRTEF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43560-1", "uniprot_id": "LAM5_YEAST", "id": "P43560-1", "name": "Membrane-anchored lipid-binding protein LAM5", "aln": "------------------------------------MSDVDNWEPVSDNEDSTDSVKQLGPPFEHASNNDNAGDTEAESLQEVPLNTETNDVRKNLVVITNQSAADEHP----------------------TEIKHDQSRTSSTSSFFSGMISSFKSNVPSPVSRSTTPTSPVSQPSIISHRREPSMGSKRRSS---------------------------------------------RRISNATIAEIGSPLQQVEKPDEVKTRLTPSQMKE---------------------------------DNYDHRR-------------FVEERYMDTPYHYASEQRNKDFHETFKSVPKDDRLLDDFNCGLNRELLYQGKLYITETHLCFNSNVLGWIAKVLIAFEDVTFMEKTSAAGLFPSAISIETKMGK-----------TLFNGFISRDAAFGLMKEVWSRTLLQKDMASENINTKAEKS-----GNGKEIDDAINSIDEENNDKD----------------ANDNDTNENDDEN-----------------------------------------------------------------------------------------ISTNETTPNSTSSSPD--KEKEKAYKLR-------------------------------------------------------------------ADSSYQYDGPIYHHSTSFPAEPMANNEFVLKELP-----------FDCAPGILFEIMFNSEQNEFLLDFLRGQEGSQITTIPNFTSIDGSSMTLKREYSYEKALHFPAGPKSTTCYVAEVIKRKDPD-TYYEVISSIRTPNVPSGGSFSTKTRYLIRWNDEITCLLRVSFWVEWTGSSW--IKGMVENGCKNGQLEAAQLMERILSKFIKNNVEECQ----------------------------ITISKEEEEQDDKEVKNKLKEVDLE----------QPREAVVTAPAIAEQQGLKVTMET----------------------------------------------------------------------------------------------------------------------------------WLFLYLIVVVLLLFNLFYIRS---------------------------------------------------IAVSLHQLVKLQLVELKL---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* .:::. *. :*. ::*: *: *.*::::* **::*.::. :** :::: : : : ::: : * .:* :*.**.: : * :* * :*: : : .:*...*::* : :: . * : : . . : . . . * : .::*. . * : . : : * : * : :. . . : . .:* * . :: : * : : : . * :* :: .. . . : : :. : : : : *: .* :. :: : . : : ", "identical_positions": 38, "similar_positions": 121, "identity": "3.0%" }, { "cls_id": "homologset.agr.SGD:S000001853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VBK7-1", "uniprot_id": "Q9VBK7_DROME", "id": "Q9VBK7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MGQNFLRRLPANRVASCPWRFAMSKRESKSFASLVLIVLLIFASN-----------------------------------PSQCESSKDDFPQAKFEWP-SFAWMRNKTTKGTPALDLKNDYSQMELANFGDFDRHPCRRVCQQ-GQSQNCYYQLVVHNYQRLGPECQR------------------CQFDERACASEHCIYGDGVANPVMAVNRMVPGPSIELCENDTVVVDVLNYLS--EPTTMHWHGVHMHRTP----EMDGAPFITQYPLQPGEVQRHEFKVDR-SGSLWYHSHVGWQRGFGVAGAFVVRQTSQENQHSQLYDYDLVEHTLMIQDIFYEY------------NLQDVRNILVNGKGRNHLSQLPDNDNRHR-----------------------------------------------------------YERLRVTPGYRYRMRVILNGIANCPVEFSIEQHRLLMISTDGNDIEPVLADGFFLTSAERFDFVLEANQYKKNYWIRIKGYEQCEN--RNIYQGAVLSYRGSARSELPQGDILDKPSSRAADEDLILVNDFRFKPAN-STAISSLRQSLDKDNNVGTVALRSVDPVPWTRYTKFLTHYS------------SFGSRTAPNGE-VLFQISDISYNSPGISLLQGRHLYQDDRYFCNKSSLAAEGRNCERELCECVNVMRLPAYRPLEMVVANY---LDSTHPFHIHGFTFRLVGQG-------VLGNLNDLRNIQELDRRGRLPRLSEDSAAVAKDTVQIPGQGYIIVRFISNNPGFWLYHCHVEAHAVQGMVAVLKIG-------------------------------------EDHQMKNIPARVR--C-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX11-1", "uniprot_id": "Q9VX11_DROME", "id": "Q9VX11-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MKFNLVQTLVFT---------------------LCLISVQIYG--------------------------------------IQDASGKR--IVSKYER---IMQMYPQLSSG------AGESSQWRAAEK-DNQRHPCRRDCAD-KQPMTCYYYMVVHYDDTMAETCKRYLQSKFRFKLSGKEYIDGIALATQLAANDDCKYADGLESEVMVVNGQLPGMNIEVCYGDTVVADVINSMH--ETTTIHWHGMHQRLTP----FMDGVPHVTQYPIEAGQAFRYRFEVDH-GGTNWWHSHTEHQRAFGLAGPLVVRMPPKLNPHAHLYDFDMSEHVIMIQDWVHNF------------VESVAENILINGRGRN-LKKGVKAAKPTL-----------------------------------------------------------YAHFPVVRGGRYRFRVIFNGVSNCPISFSIDKHDLVVIASDGNDIEPVEVQRIMFHGAERFDFVLHANQEVSNYWIRVKGYSFCAK--NQLHQEAVLHYRDADTRALDT-----HTLSYAYDAPGKTLNELGDDASG-ARAG----------NSISLANLNAQRPEPEVAPS--VTFYT------------SMNAFEVRQGEGFRFQMDDISFSMPKMSLLQTRNLGVG-QFFCNRSQQADLGFNCRQRHCQCSNVIQVPANQQVEFVISSL---SQTPHPIHLHGYTFRVVGMG-------VLGEQ-KIGQIEQIDKKTPLPRRAKG--APLKDSVQVPAFGYTILRFYSNSPGYWMFHCHISPHSENGMAAVVRVG-------------------------------------EDVEMKMCPVSNCGLCSSVA---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLC3-1", "uniprot_id": "Q9VLC3_DROME", "id": "Q9VLC3-1", "name": "", "aln": "MSVSHNYDQMSQPTNTTTTQTKASKRPSRFNSKMPVVNSRLAELARITVLLTALLVSYASGLQTVGESADDNTICLYREYNTTYRKEIGAVWFASKDPCLVYSCAAGVAKDPQAHIVATQVDCNEFYCEVGSELRSVEGSCCGECVRTHCQHNHTLYAVGESWHNDADCTLIECGRLDNGQIVMNTYKRNCPALTEDCPASRLEERNCCPYCRPLQTARIEELQDNVAESTDDIWTAEWYRNHPCNRDCQVGAEPMTCRYKFVVEWYQTFSKACYD------------------CPRNLTDCSRPHCVMGDGLERSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLG-ESTSIHWHGLHQKKTP----YMDGVPHITQCPITPHATFRYSFPADL-SGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLYDFDLSEHVMIVQDWIHDTGASIFSYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQVDFVQTLPRQARLAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRYRFRIINAEYLNCPIVVSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIRLKGLMDCSEVFTSAFQVAILRYEGAPDEEPTA------ELSYGHKAEGIELNVMNRGPGYPDTKTVAEMRALPIYDHVSGIDHDTLKPEADYKFFIYYDFYTKNNPDFHDKDLYAMDMEMTQQNRLYTPQLNHITLNFPSLALLPSRSQLKD-SDFCNETSLMDQGIDCRQEFCKCHHVLQVPLGAVVEMIIVDEGFQYYANHPFHLHGNAFRVMGLE-------RLGENVTVEMIKQLDQFNLLKRNLDN--PPVKDTVTIPDGGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVG-------------------------------------NDDQMVPVPENFPTCGDYNPDLRSDGGTTEDSGSSKPITATPPNTGGGGSGLEPTWITLMISSMLVKLYR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF30-1", "uniprot_id": "A0A0B4KF30_DROME", "id": "A0A0B4KF30-1", "name": "", "aln": "------------------------------------MKAMDLNGFYQTFISFLIWGAFSNFPEVFAVRVANSQQNQPKKENQPDLTPMGSFWQQHVATPSSSTPFDSPFFSATHGLVQTHPSIGGSHSGPAPLNGNSLGSGAPSSILAGTKPALTAG-----------------------------SGYLNSRGSLPTSARYPANKITGTVVEPNPKSPFRHLDFSTSATAELRRNPALSAPDECARACREGEPPRICYYHFTLEYYTVLGAACQVCTP----------------NATNTVWSHCQCVLADGVERGILTANRMIPGPSIQVCENDKVVIDVENHMEG-MEVTIHWHGIWQRGSQ----YYDGVPFVTQCPIQQGNTFRYQWTGN--AGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTHIMLISDWLHEDAAERYPGRLAVNTGQDPESMLINGKGQFRDPNTGFMTNTPL------------------------------------------------------------EIFTITPGRRYRFRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYWIQLRGLGECGIR--RAQQLAILRYARGPYQPASS-----PPTYDVGIPQGVILNPLDAICDRKRADAVCVSN----LKNAKKVDKGVLVERPDVKIFLPFRFFVYEPKALFIPN-TYNRFLVASDADHLISLIDEVSYISPPSPMLSQYNDIPQEYYCNGDNRPVDCG-----ENCQCTHKIDVPLNAIVEVVLVDEVQQINISHPFHLHGTSFYVLGLGR---SPDKQIQRMNLKHALELDQRGLLERQYLK--PSLKDTVAVPNNGYAILRFRADNPGFWLFHCHFQYHIVIGMNLVFQIG-------------------------------------TPNDLPPVPPNFPRCGNHLPPIKTI----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43561-1", "uniprot_id": "FET5_YEAST", "id": "P43561-1", "name": "Iron transport multicopper oxidase FET5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFYSFVWSVLAASVALAKT-------------------HKLNYTASWVTANPDGLHEKRMIGFNGEWPLPDIHVEKGDRVELYLTNGFQDNTATSLHFHGLFQNTSLGNQLQMDGPSMVTQCPIVPGQTYLYNFTVPEQVGTFWYHAHMGAQYGDGMRGAFIIHDPEEP------FEYDH-ERVITLSDHYHEN----------YKTVTKEFLSRYNPTGAEPIPQNILFNNTMN------------------------------------------------------------VTLDFTPGETYLFRFLNVGLFVS-QYIILEDHEMSIVEVDGVYVKPNFTDSIYLSAGQRMSVLIKAKDKMPTRNYAMMQIMDETMLDVVPPELQLNQTIQMRYGHSLP----------EARALNIEDCDLDRATND---------------FYLEPLIERDLLAHYDHQIVMDVRMVN----------------LGDGVKYAFFNNITYVTPKVPTLTTLLTSGKLASDPRIYGDN----------------INAQLLKHNDIIEVVLNNYD---SGRHPFHLHGHNFQIVQKSPGFHVDEAYDESEQDEMTVPYNESAPLQPFPER--PMVRDTVVLEPSGHVVLRFRADNPGVWYFHCHVDWHLQQGLASVFIEAPVLLQEREKLNENYLDICKAADIPVVGNAAGHSNDWFDLKGLPRQPEPLPKGFTTEGYLALIISTIIGVWGLYSIAQYGIGEVIPNDEKVYHTLREILAENEIEVSRG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. . : . . : * * *.: .* : : * : .::*:**: . : ** . :** *: . : : *: ::*:* * *: *..::: . :::* : : :.* :: * * : . * * :*.: . . :: * : : ** :.. . : ..:* ..:: *. : : : : : :: * . * . . : : :*.:: . **:*:** * :: : :. * . :*:* : *: ::** :..** * :***.. * *: *. . : * ", "identical_positions": 57, "similar_positions": 111, "identity": "5.5%" }, { "cls_id": "homologset.agr.SGD:S000001855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRN3-1", "uniprot_id": "D3ZRN3_RAT", "id": "D3ZRN3-1", "name": "", "aln": "---------------------------------------------------------------MVDDELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ3-1", "uniprot_id": "ACTBL_MOUSE", "id": "Q8BFZ3-1", "name": "Beta-actin-like protein 2", "aln": "---------------------------------------------------------------MVDDELTALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q562R1-1", "uniprot_id": "ACTBL_HUMAN", "id": "Q562R1-1", "name": "Beta-actin-like protein 2", "aln": "---------------------------------------------------------------MTDNELSALVVDNGSGMCKAGFGGDDAPRAVFPSMIGRPRHQGVMVGMGQKDCYVGDEAQSKRGVLTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHIVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVRAAASSSPERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESSGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIITLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZVF9-1", "uniprot_id": "ACTB2_DANRE", "id": "Q7ZVF9-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------MDDEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68032-1", "uniprot_id": "ACTC_HUMAN", "id": "P68032-1", "name": "Actin, alpha cardiac muscle 1", "aln": "--------------------------------------------------------------MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68035-1", "uniprot_id": "ACTC_RAT", "id": "P68035-1", "name": "Actin, alpha cardiac muscle 1", "aln": "--------------------------------------------------------------MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68033-1", "uniprot_id": "ACTC_MOUSE", "id": "P68033-1", "name": "Actin, alpha cardiac muscle 1", "aln": "--------------------------------------------------------------MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68134-1", "uniprot_id": "ACTS_MOUSE", "id": "P68134-1", "name": "Actin, alpha skeletal muscle", "aln": "--------------------------------------------------------------MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68133-1", "uniprot_id": "ACTS_HUMAN", "id": "P68133-1", "name": "Actin, alpha skeletal muscle", "aln": "--------------------------------------------------------------MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "--------------------------------------------------------------MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TN73-1", "uniprot_id": "A0AB32TN73_DANRE", "id": "A0AB32TN73-1", "name": "", "aln": "--------------------------------------------------------------MCDDDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63268-1", "uniprot_id": "ACTH_MOUSE", "id": "P63268-1", "name": "Actin, gamma-enteric smooth muscle", "aln": "--------------------------------------------------------------MCEEET-TALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63267-1", "uniprot_id": "ACTH_HUMAN", "id": "P63267-1", "name": "Actin, gamma-enteric smooth muscle", "aln": "--------------------------------------------------------------MCEEET-TALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63269-1", "uniprot_id": "ACTH_RAT", "id": "P63269-1", "name": "Actin, gamma-enteric smooth muscle", "aln": "--------------------------------------------------------------MCEEET-TALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62737-1", "uniprot_id": "ACTA_MOUSE", "id": "P62737-1", "name": "Actin, aortic smooth muscle", "aln": "--------------------------------------------------------------MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62736-1", "uniprot_id": "ACTA_HUMAN", "id": "P62736-1", "name": "Actin, aortic smooth muscle", "aln": "--------------------------------------------------------------MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62738-1", "uniprot_id": "ACTA_RAT", "id": "P62738-1", "name": "Actin, aortic smooth muscle", "aln": "--------------------------------------------------------------MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "--------------------------------------------------------------MC-DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02572-1", "uniprot_id": "ACT2_DROME", "id": "P02572-1", "name": "Actin-42A", "aln": "--------------------------------------------------------------MC-DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53501-1", "uniprot_id": "ACT3_DROME", "id": "P53501-1", "name": "Actin-57B", "aln": "--------------------------------------------------------------MC-DDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITSLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10981-1", "uniprot_id": "ACT5_DROME", "id": "P10981-1", "name": "Actin-87E", "aln": "--------------------------------------------------------------MC-DDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02574-1", "uniprot_id": "ACT4_DROME", "id": "P02574-1", "name": "Actin, larval muscle", "aln": "--------------------------------------------------------------MC-DEEASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILSLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTPEALFQPSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83967-1", "uniprot_id": "ACT6_DROME", "id": "P83967-1", "name": "Actin, indirect flight muscle", "aln": "--------------------------------------------------------------MC-DDDAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9BYX7-1", "uniprot_id": "ACTBM_HUMAN", "id": "Q9BYX7-1", "name": "Putative beta-actin-like protein 3", "aln": "----------------------------------------------------------------MDDDTAVLVIDNGSGMCKAGFAGDDAPQAVFPSIVGRPRHQGMMEGMHQKESYVGKEAQSKRGMLTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGFTHTVPIYEGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTTAEQEIVRDIKEKLCYVALDSEQEMAMAASSSSVEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHKTTFNSIVKSDVDIRKDLYTNTVLSGGTTMYPGIAHRMQKEITALAPSIMKIKIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "----------------------------------------------------------------MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P45891-1", "uniprot_id": "ACTY_DROME", "id": "P45891-1", "name": "Actin-like protein 53D", "aln": "----------------------------------------------------------MSSEVDSNSHHAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYPIEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHG----KVETYELPDGQKIVLGCERFRCPEALFQPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y615-1", "uniprot_id": "ACL7A_HUMAN", "id": "Q9Y615-1", "name": "Actin-like protein 7A", "aln": "MWAPPAAIMGDGPTKKVGNQAPLQTQALQTASLRDGPAKRAVWVRHTSSEPQEPTESKAAKERPKQEVTKAVVVDLGTGYCKCGFAGLPRPTHKISTTVGKPYMETAKTGDNRKETFVGQELNNTNVHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFEAFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTAYLLGLLNSAGNEFT-QDQMGIVEDIKKKCCFVALDPIEEKKVPLSEHTIR--YVLPDGKEIQLCQERFLCSEMFFKPSLIKSMQLGLHTQTVSCLNKCDIALKRDLMGNILLCGGSTMLSGFPNRLQKELSSMCP-NDTPQVNVLPERDSAVWTGGSILASLQGFQPLWVHRFEYEEHGPFFLYRRCF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:* * *:* *.**. * :.: :*:* . : :*. .. *.* *:.**:: :** :: :* : : :: * : . *:::.*:.*: **** ::::** *: **:::: *: **:*: *** * *:: *.*.:: **** * .** *:* ** :** ** :* . * : : **.::*:* *:*::: :* * ****: * : *** .* :*:*..: *:. . .: :.*: ::::: * ::.**:** .: .*: ::: :.* :: . *.* :** ***:**** ** :*: **:* *. :::::**", "identical_positions": 108, "similar_positions": 123, "identity": "24.6%" }, { "cls_id": "homologset.agr.SGD:S000001856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NYB7-1", "uniprot_id": "RAB1A_RAT", "id": "Q6NYB7-1", "name": "Ras-related protein Rab-1A", "aln": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG----ATAGGAEKSNVKIQS-TPVKQSGGGCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62820-1", "uniprot_id": "RAB1A_HUMAN", "id": "P62820-1", "name": "Ras-related protein Rab-1A", "aln": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG----ATAGGAEKSNVKIQS-TPVKQSGGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62821-1", "uniprot_id": "RAB1A_MOUSE", "id": "P62821-1", "name": "Ras-related protein Rab-1A", "aln": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG----ATAGGAEKSNVKIQS-TPVKQSGGGCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0U4-1", "uniprot_id": "RAB1B_HUMAN", "id": "Q9H0U4-1", "name": "Ras-related protein Rab-1B", "aln": "---MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPG----AASGG-ERPNLKIDS-TPVKPAGGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92928-1", "uniprot_id": "RAB1C_HUMAN", "id": "Q92928-1", "name": "Putative Ras-related protein Rab-1C", "aln": "---MNPGYDCLFKLLLIGDSGVGKSCLLLRFADDPYTESYISTIGVDFKIQTIELDGKTIKLQIWDTAGQERFWTITSSYYRGAHGFLVVYDVTDQESYANVKQWLQEIDRHASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKQMGPG----AASGG-ERPNLKIDS-TPVKPAGGGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1G1-1", "uniprot_id": "RAB1B_MOUSE", "id": "Q9D1G1-1", "name": "Ras-related protein Rab-1B", "aln": "---MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPG----AASGG-ERPNLKIDS-TPVKPASGGCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10536-1", "uniprot_id": "RAB1B_RAT", "id": "P10536-1", "name": "Ras-related protein Rab-1B", "aln": "---MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTVTSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPG----AASGG-ERPNLKIDS-TPVKSASGGCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O18332-1", "uniprot_id": "O18332_DROME", "id": "O18332-1", "name": "", "aln": "MSSVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPP----SSATD-NASKVKIDQGRPVENTKSGCC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P01123-1", "uniprot_id": "YPT1_YEAST", "id": "P01123-1", "name": "GTP-binding protein YPT1", "aln": "---MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNVNLKG-QSLTNTGGGCC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. ** ********:************:**.**:.***********:*:******:************* *:*******:**:::*** *****: .** **:**:*:* ..* *******.**. *:**: .* *:* :******* .:****::*:*** :**: :. :: : ::::. .: : .***", "identical_positions": 120, "similar_positions": 50, "identity": "57.14%" }, { "cls_id": "homologset.agr.SGD:S000001857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85108-1", "uniprot_id": "TBB2A_RAT", "id": "P85108-1", "name": "Tubulin beta-2A chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGN------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13885-1", "uniprot_id": "TBB2A_HUMAN", "id": "Q13885-1", "name": "Tubulin beta-2A chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGN------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TMM9-1", "uniprot_id": "TBB2A_MOUSE", "id": "Q7TMM9-1", "name": "Tubulin beta-2A chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGN------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CWF2-1", "uniprot_id": "TBB2B_MOUSE", "id": "Q9CWF2-1", "name": "Tubulin beta-2B chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGN------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVA1-1", "uniprot_id": "TBB2B_HUMAN", "id": "Q9BVA1-1", "name": "Tubulin beta-2B chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGN------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P9T8-1", "uniprot_id": "TBB4B_RAT", "id": "Q6P9T8-1", "name": "Tubulin beta-4B chain", "aln": "---------------------------MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG------KYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTACLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68371-1", "uniprot_id": "TBB4B_HUMAN", "id": "P68371-1", "name": "Tubulin beta-4B chain", "aln": "---------------------------MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG------KYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68372-1", "uniprot_id": "TBB4B_MOUSE", "id": "P68372-1", "name": "Tubulin beta-4B chain", "aln": "---------------------------MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG------KYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D6F9-1", "uniprot_id": "TBB4A_MOUSE", "id": "Q9D6F9-1", "name": "Tubulin beta-4A chain", "aln": "---------------------------MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG------NYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE-GEFEEEAEEEVA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04350-1", "uniprot_id": "TBB4A_HUMAN", "id": "P04350-1", "name": "Tubulin beta-4A chain", "aln": "---------------------------MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG------NYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE-GEFEEEAEEEVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7Z8-1", "uniprot_id": "A0A8M1N7Z8_DANRE", "id": "A0A8M1N7Z8-1", "name": "Tubulin beta chain", "aln": "MGEVSTPSQLKKGKGSLLSQIQITRAKMREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRINVYYNEASGG------KYVPRAVLVDLEPGTMDSVRSGPFGQVFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPSYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRSLTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEGEEELA------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P99024-1", "uniprot_id": "TBB5_MOUSE", "id": "P99024-1", "name": "Tubulin beta-5 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGG------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07437-1", "uniprot_id": "TBB5_HUMAN", "id": "P07437-1", "name": "Tubulin beta chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGG------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P69897-1", "uniprot_id": "TBB5_RAT", "id": "P69897-1", "name": "Tubulin beta-5 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGG------KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24560-1", "uniprot_id": "TBB1_DROME", "id": "Q24560-1", "name": "Tubulin beta-1 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGG------KYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEVDEN----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P61857-1", "uniprot_id": "TBB2_DROME", "id": "P61857-1", "name": "Tubulin beta-2 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGA------KYVPRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGDE-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ERD7-1", "uniprot_id": "TBB3_MOUSE", "id": "Q9ERD7-1", "name": "Tubulin beta-3 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSH------KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDDEESEAQGPK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QRB4-1", "uniprot_id": "TBB3_RAT", "id": "Q4QRB4-1", "name": "Tubulin beta-3 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSH------KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDDEESEAQGPK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13509-1", "uniprot_id": "TBB3_HUMAN", "id": "Q13509-1", "name": "Tubulin beta-3 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSH------KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q922F4-1", "uniprot_id": "TBB6_MOUSE", "id": "Q922F4-1", "name": "Tubulin beta-6 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGTKFWEVISDEHGIDQAGGYVGDSALQLERISVYYNESSSK------KYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQNKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVNDGEEAFEDEDEEEINE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUF5-1", "uniprot_id": "TBB6_HUMAN", "id": "Q9BUF5-1", "name": "Tubulin beta-6 chain", "aln": "---------------------------MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQ------KYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATANDGEEAFEDE-EEEIDG----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08841-1", "uniprot_id": "TBB3_DROME", "id": "P08841-1", "name": "Tubulin beta-3 chain", "aln": "---------------------------MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVNQEEVEGDCI---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NNZ2-1", "uniprot_id": "TBB8B_HUMAN", "id": "A6NNZ2-1", "name": "Tubulin beta 8B", "aln": "---------------------------MREIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGG------RYVPRAVLVDLEPGTMDSVHSGPFGQVFRPDNFISGQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGCYLTVAAIFRGRMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPPRGLKMSATFIGNNAAIQELFTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEVA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ZCM7-1", "uniprot_id": "TBB8_HUMAN", "id": "Q3ZCM7-1", "name": "Tubulin beta-8 chain", "aln": "---------------------------MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGG------RYVPRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEVA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AQ07-1", "uniprot_id": "TBB1_MOUSE", "id": "A2AQ07-1", "name": "Tubulin beta-1 chain", "aln": "---------------------------MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGK------KYVPRAVLVDLEPGTMDSIRSSRLGVLFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAESDIHDLVSEYQQFQDVRAGLEDSEED-VEEAEVEAEDKDH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R8B6-1", "uniprot_id": "M0R8B6_RAT", "id": "M0R8B6-1", "name": "Tubulin beta chain", "aln": "---------------------------MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGK------KYVPRAVLVDLEPGTMDSIRSSRLGILFQPDSFVHGNSGAGNNWAKGHYTEGAELIETVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAEADILDLVSEYQQFQDVRAGLEDIEEGGEEEAEMGAEDKNH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4B7-1", "uniprot_id": "TBB1_HUMAN", "id": "Q9H4B7-1", "name": "Tubulin beta-1 chain", "aln": "---------------------------MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGR------KYVPRAVLVDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVLEVVRHESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENADACFCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGKMSTKEVDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNRVSEHFSAMFKRKAFVHWYTSEGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEE-DEEVTEEAEMEPEDKGH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02557-1", "uniprot_id": "TBB_YEAST", "id": "P02557-1", "name": "Tubulin beta chain", "aln": "---------------------------MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSG------KWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQEATVEDDEEVDENGDFGAPQNQDEPITENFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****: . ******** *** * ** :* * * . :* :*:.*:.:*: . .:***: :******:::::.. * :*:**.:: *: .*** ****:******* : *::*:*:*.* **.*****:.***************:.*:***:***:: ::*::****.**********.**:***:*::* :.********** :**:: *:*****:*** .***:*:.**:*****:********:********** *:****: ***.:*:*:*.*****:**::* ***.* *.* ***.* .*** :. :**:::: :* :**. *.:*:*:* :.***.:.*:**.*: **:.*.::***:*. :.::*:***:*:**:**:*.**** ** *** :: ********:*:. . ", "identical_positions": 242, "similar_positions": 130, "identity": "49.39%" }, { "cls_id": "homologset.agr.SGD:S000001858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y8F7-1", "uniprot_id": "A0A8I5Y8F7_RAT", "id": "A0A8I5Y8F7-1", "name": "DNA-directed RNA polymerase", "aln": "---MSALRWTRGAAGLGRVLRSPGPHRPASEEGPLSGLGS--------------------------------------------SRRRSAASPREQAVQR--EWGHAELLEVLEARVRQLR---------------AEGAPEMRVKKVQVDQPPQGRSS--------------------------------RWAQKLEAEKKVKQRHQA------KADLQKQPLESR--TLHTEPRIRSKKLAGYLHQSKKGAPKSSEEEQLARVLQAVLAKLGSRE----------AGTPARTKAKAVETHILFLQQK------------LRTFFECCVCTGQLPLAHHMLVTHHNNQDK-------QQVLTLDMYNMVLLGWARKGSFRELVYVFIMLTDAGLSPDLHSYAAALQCMGRRDQD---AHTIQRCLKQMAEEGFQPQ----LLFTNLVLEEEDRAALLRAVVKGEPAFC---PPPQAS------NLVSTPVLLKDFYSKEGPVSYPKLHLP----LDTLQDLFYQQLHVELSSSVSVQSVEEAPVMTKEVIEARKTLKALRSKWEVELLRVLRETKAKMGSQA---YEGQPTLYPFLCLLSEGEFVSILMQALQVLPAQGEPLF----QLAQNLGLQVFNRHLVKQKQVTNHVQKLGQQYSQYLRLLASDTQV---APCLPREYWDS--LGSLETPAQQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARHG-------AQNFIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKIMRATEGTTQHQRLLERCPPAQLHGALDALTQLGNCAWRVNGRLLDLVLQIFRDKGCMRLGVPPPRSEAP----RPAKHQLPPGSTPVHKSELRKELARCLKAAREMHSLRSEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLRKRDSLRMRLAFADEVMGEILDSADNPLTGQKWWMKADEPWQTLACCMEVAQAVRSPDPTAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEELRQQDAKEGLQVAQALEGFVSRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSSTRAIQRWLTESANLISHAGWP------------------VEWVTPLGIPIIQPYHR-ESKIQVKGG-LQSITFTSSVDDSQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCFWTHAADIPMMNEVCREQFVRLHSEPILEDLAKFLEKRFCSVS-----------------------------------------------------------------------------KSLKPSELALIT-KLQETLRSLPETGKSFKGSMRIGP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKF1-1", "uniprot_id": "RPOM_MOUSE", "id": "Q8BKF1-1", "name": "DNA-directed RNA polymerase, mitochondrial", "aln": "---MSALRWTRSAAGLGRVLRSPGPHRPPSEEGTFGGFCS--------------------------------------------SRRSSAASPREQHVLR--EWGHAELLEVLEARVRQLR---------------AEGTPEMRVKKVQVDRPPQGHSS--------------------------------RWAQKLEAEKRVKQRRQK------EVDQQKQALTQEFWTLHKEPKIWNKKLAGYLQPSKKGTPTNSEEKQLAQALQAALGRLSSRE----------AEALARKKAKAVEAQILVLQQK------------FLAFFECCVCTGQVPLAHHVLVTHHNNGDR-------QQVLTLHMYNTVMLGWARKGSFRELVYVFLMLKDAGLSPDLCSYAAALQCMGRRDQD---VRTIQRCLKQMMEEGFQPQ----LLFTDLVLEEEDRAALLRAVVKAEPAFR---PPPQAP------SPVNTSTLLKDIYSKEGPVSYPKLHLP----LDTLQDLFYQQLHVELSSSVCVQSVEKAPVMSKEVIEARKTLQALREQWEVELLRVLRETKATMGRQA---YEGQPTLYPFLCLLSEGEFVSILMQVLKVLPAQGEPLI----QLAHNLGLRVLNRHLVKQKQVTNHVQKLGQRYSQYLQLLASDTQV---APCLPREYWES--LGPLEAPAQQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARQG-------AQRSIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKLMRATEGTTQHQRLLEQCPPAQLHGPLDALTQLGNCAWRVNGHLLDLVLQIFRDKGCMPLGVPPPRSEAP----RPARYQLPPGSTPVHKSELRKELARCLKVAREMHSLRSEALYRLSLAQHLRHRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLKKGDSLRMRLAFADEVMEEILDSADNPLTGRKWWMEADEPWQTLACCMEVAHAVRSPDPAAYISHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEEFRQQDAKEGLRVAQVLEGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFTSTRAIQHWLTESANLISHAGWP------------------VEWVTPLGIPIIQPYHR-ESKVQVKGG-LQSITLTSSVDESQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLIFVSVHDCFWTHAADIPTMNEVCREQFVRLHSQPILEDLAKFLKKRFCSVSSI---------------------------------------------------------------------------KSLKSSERALVT-KLQETLQSLPKTGTFDLGQVIRSTYFFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00411-1", "uniprot_id": "RPOM_HUMAN", "id": "O00411-1", "name": "DNA-directed RNA polymerase, mitochondrial", "aln": "---MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCG--------------------------------------------PRRSSSASPQEQDQDRRKDWGHVELLEVLQARVRQLQ---------------AESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVP---------CGRWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQLARLLQEAPGKLSLDV----------EQAPS---GQHSQAQLSGQQQR------------LLAFFKCCLLTDQLPLAHHLLVVHHGQRQK-------RKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQD---AGTIERCLEQMSQEGLKLQ----ALFTAVLLSEEDRATVLKAVHKVKPTFS---LPPQLP------PPVNTSKLLRDVYAKDGRVSYPKLHLP----LKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREV---YEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFT----TLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVP--EPCLPRQYWEE--LGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHR-------SSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAP----QPPEAHLPHSAAPARKAELRRELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSV------------------VEWVTPLGVPVIQPYRL-DSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQ----------------------------------------------------------------------------KILEAS-------QLKETLQAVPKPGAFDLEQVKRSTYFFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPW4-1", "uniprot_id": "Q9VPW4_DROME", "id": "Q9VPW4-1", "name": "DNA-directed RNA polymerase", "aln": "---MYRLLSANRAAAVQKALRVPPTAHPTTTTATTTTVCCGCGIAPSNFVHYQQYYQMLYRQMPAGAITAKTTTTTTRTQTTTPTQTDAVAQAKKKRLRKPRYAKYVELLEVTEQAISERRSRVKRLKSKKLADFIHKAQQQILERRAREDRKDKKTKCVLDLAQRQPVEYQKIDMEALDGSILESGVYDDRPMLFFGKDEYTKQVIAN------PEEVQNILKSFQNFRDIIESMENDQHEADFGLSTTKVHPEEHEMLDPFEAIEPYISPLDKSKRSVTTVAVPNASAVTTKSKKRFKSKVHVNEEQERLAKQRALHINLNTYLNVCVSANMLNRALSTIIAYRGKVRKSSLPHMSEGLITIDLYNILLHGYAGKGSFDRAQEVFKLIEEDGLSFNEQTYAAIFECLGRLEPDEENHQYISEYVSKAEKEGFSLN----QIMDRSKFVADQRDIALDAIRRLRPDFKPVYVPPQLGYDNELLDHLNEHVIPVGAKKEPGKADYAIMNSKRGYTAAQLEQLAREQLKIELDGSITIKSIEKSKEFAN-SEKCRELLKELEDTWRKQISAAIVRDLNTLRAQVRFKPHGFMNYYTYLKTLDASHFADILIKELYKLAEGSETFSPTVGQLYKELGQKVQQRYQIEQKKHNGTLEKIGEIYSSYCELWGSGMSQDNTRQAWQRLVYEQRESGPSMDLLEVPWPSNVLTGVGRFLYNILMRDIKIDAHIMRQKSKSKAAAQPQNLLPAFYTLFRNQGRFVKEEVKPHPVLSRLFRASRQQTLTFDSNLVPMLCPPQPWSTPHNGGYLLNKTELIRLPHQAIQQWDRIMASNPQHLYPALDSLNQLASVPWRVNTQLLDVIIKVFQNGGDVKLDVPQPPSSLPPLPTLPAKDAEGNATSSEDRAKQFRDKLGHRRKQAEMYSLWCDALYRLSLAQHYRDKVFWLPHNMDFRGRVYPVPPHLNHLGSDLARSMLIFDQAQPLGVDGLSWLKLHCINLTGLKKRDSVRERLLYAEEIMPDILDSADNPLTGRMWWSKSDEPWQTLACCMEIANVHRCPDPAAYLSRFPIHQDGSCNGLQHYAALGRDEAGARSVNLAPSAIPQDVYSAVAALVEKSRKADAQNGLHVAEALAGFVRRKVIKQTVMTTVYGVTRYGARLQIARQLKDIDDFPKDWVWPASTYLTTKTFESLREMFTSTREIQDWFTECARLISGVCSQN-----------------VEWVTPLGLPVVQPYNRQEMKHSPRSG--FKVSANMPMDLYERPNILKQKNAFPPNFIHSLDSSHMMLTSLHCERQGITFVSVHDCFWTHANTVPELNRMCREQFVALHSQPILEQLSEFMRHTYSFKDSD---------------------------------------------------------------------------FINDGSVEDLSKRQLNRILKQMPQKGDFDLRNVLDSVYFFS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13433-1", "uniprot_id": "RPOM_YEAST", "id": "P13433-1", "name": "DNA-directed RNA polymerase, mitochondrial", "aln": "MLRPAYKSLVKTSLLQRRLISSKGSKLFKPSPDSTSTILIS------------------------------------------EDPLVTGSSPTSSTTSGIISSNDFPLFNKNRKDAKSSIS------------YQWKNPSELEFDPFNKSHASAVTSMTRTRDVMQLWSLLEACLQSN---------LMKRAFSILESLYLVPEHKQR-----FIEDYNMYLNSFSKNDPNFPILKMNEKLTNDLETSFKDVNYNDKTLAIMIHHALNFHSTTSSMLLKPIISAYLKMSVNGIREIFSCLDILTISDLN-----------ILMNDLKVITPSQLPNSVRPILESLTLSPTP-----VNNIENEEGLNKVEAENDSKLHKASNASSDSIKKPSLDPLREVSFHGSTEVLSKDAEKLIAVDTIGMRVIRHTLLGLSLTPEQKEQISKFKFDANDNVLKMKPTKNDDNNNSINFFEIYNS-----LPTLEEKKAFESALNIFNQDRQKVLENR---ATEAARERWKHDFEEAKARGDISIEKNLNVKLWKWYNEMLPLVKEEINHCRSLLSEKLSDKKGLNKVDT-----NRLGYGPYLTLIDPGKMCVITILELLKLNSTGGVIEG-----MRTARAVISVGKAIEMEFRSEQVLKSESQAFRDVNKKSPEFKK---LVQNAKSVFRS----SQIEQSKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVT----KAKVHGEAPAFAHGYQYHNGSKLGVLKIHKTLIRQLNGER-LIASVQPQLLPMLVEPKPWVNWRSGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTVNRKVFDVVSQVWN-KGEGFLDIPGAQDEMV------LPPAPPKNSDPSILRAWKLQVKTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYFPHNLDFRGRAYPLSPHFNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLP-LKDRVAFTESHLQDIKDSAENPLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEFISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYAHVARLVQKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQLSPIFDDRKE-SLDFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKSIRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYRE-ESKKQVETN--LQTVFISDPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFASVHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIGKLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIEDRNVGEKMVTTVSLFEDITDLDALELENGGDENSGMSVLLPLRLPEIPPKGDFDVTVLRNSQYFFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . . : :.. .. *:: . . : :: : . * : . : : .:: :. : . : .: .: : : .. : : :: . : . . * : : : . :: . : :.: . * : : *:. : : ::. : . . :. . . :. . .::. . : : . :: . . : : :. . .:* :. .. : : * * . : : :: : . : . .. . : : . . : *. : :* * .:*:: :: *.: : :. :* * . : :. :.:. :*** * ** . :.*.: . : ::* . . * . : *.*. *. .* ** :::*:: :::. * *.:* . .. : . : . . * .:: *:*.:*: . :::***:*****.** .**:****.*::*.:* * ..: ** **.***:* ** *: * :: *: :::. : :* ***::**** ** :::***:** *:*: .. : :* ::*: *:****:*********** * ** .*** ** ***** ** *: . *:.* . *: * . : ***:****** ***** *. :** ::* : * :: * **. :.*.:::*:* .:: ** *: *.*. ** * *.****:*::***. : * . . . . * :** .:*********:***:*:: .* ::*: *.****.:**** : :* : ****: **. :: * . : : : . * * :* * : . ", "identical_positions": 208, "similar_positions": 304, "identity": "14.08%" }, { "cls_id": "homologset.agr.SGD:S000001859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI63-1", "uniprot_id": "MOB2_MOUSE", "id": "Q8VI63-1", "name": "MOB kinase activator 2", "aln": "-------------------------------------------------------------------------------MDWLMG----------------------------------------------------KSKAKPNGKKPAAEEKKVYLEPEHTKSRITDFEFKELVVLP-REIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMA-VCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPG------------------------------NSGATGDGANSGASGAQNHVKER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBN8-1", "uniprot_id": "A0ABK0LBN8_RAT", "id": "A0ABK0LBN8-1", "name": "MOB kinase activator 2", "aln": "------------------------------------------------------------------------MALSPEHVGWLCNPHIMVGEHCSLPSERTLLSHPPKTGFRCK------------MVLQAVSKVLRKSKAKPNGKKPAAEEKKVYLEPEHTKSRITDFEFKELVVLP-REIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMA-VCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPG------------------------------NSGATGDGASSGASGAQNHVKER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70IA6-1", "uniprot_id": "MOB2_HUMAN", "id": "Q70IA6-1", "name": "MOB kinase activator 2", "aln": "-------------------------------------------------------------------------------MDWLMG----------------------------------------------------KSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLP-REIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMA-VCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGAGG----------------------------VHSGGSGDGAGSGGPGAQNHVKER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKY9-1", "uniprot_id": "A0A8M2BKY9_DANRE", "id": "A0A8M2BKY9-1", "name": "", "aln": "-----------------------------------------------------------------MVGDHSITGERPPKSGLSCK-----------------------------------------MVLQAVGKVLRKGKGKPNGKKPPTEEKKHYLDAEYTKVRVVDFELKELVVLP-REIDLNEWLASNTTTFFNLINLQYSTISEFCTGDTCPAMS-AYSTTYFWYDEKGKKTKCTAPQYVDFVMSSVQKLVTDEDIFPTKYGKEFPNTFDSLVKKICRYLFHVLAHIYWSHYKETVAMDLHGHLNTLYTHFIVFIREFNLMDPKETSIMDDLTEALC-------------------------------------------TPLPP--QNHVTER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N0E0-1", "uniprot_id": "A0A8M1N0E0_DANRE", "id": "A0A8M1N0E0-1", "name": "", "aln": "-----------------------------------------------------------------------MHSQKTPRNGLSCK-----------------------------------------MVLQAVGKVLRKSKTKPNGKKAPPEEKKHYLEPEYTKVRVADFDLKDLVALPTKEIDLNEWLASNTTTFFNLINLQYSTISEFCTGDTCQAMT-AYNTIYYWYDERGKKTKCTAPQYVDLVMTFVQKLVTDEEIFPTKYGKDFPNSFESLVKKVCRYLFHVLAHIYWAHFKEIVALDLQGHLNTLYAHFIVFIREFNLIDPKETCIMDDLSEVLC-------------------------------------------APLPPTAHNHVTER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQG1-1", "uniprot_id": "MOB2_DROME", "id": "Q8IQG1-1", "name": "MOB kinase activator-like 2", "aln": "MNWAISNLTGGNRVSRAILVRYSSVPLADATNDGSSTAPQTPTASTPRPSSSHSSLSSTFAATFLHASSRHIPGRAVPRQNANGQNGGKGNASGAGGGAGGGGAGGASGGTGGTGAQAAGQLSLPLDVEETVTCFCRKARRKERDGDQNSTDTKLYLEESVLERKLPEADLKALVDLP-AGLDYNEWLASHTLALFEHVNLVYGTISEFCTQSGCADMTGPGNRTYLWFDEKGKKTRVAAPQYIDYVMTFTQKTVSDESIFPTKYANEFPGSFESIARKILRLQFHVIAHLYAAHFREIALLGLHTHLNLTFAHLTALHRRFNLIDEKETDVLRDLEVALRLTDDTGGCQDATSTTSSVHDHSHSGDLQHQSLQQQQQHHNSSSNSTSSAEAFHVNSQSNNGSTSASASVSLIDGDAVAPPICTQPEAGAGCKPAGSSGLLGGILGDLTSGEFGDTTRYCTSAVPQAAAAAGAGVGGTAIGATDAAALNNGAGALHLNFSNNNNNNHNLNHHHHHHHHHGHHGHHHAAQQQQQHSGLIQCNAAGGGGNATGVATGGATAAASSTTTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43563-1", "uniprot_id": "MOB2_YEAST", "id": "P43563-1", "name": "CBK1 kinase activator protein MOB2", "aln": "----------------------MSFFNFKAFGRNSKKNKNQPLNVAQPPAMNTIYSSPHSSNSRLSLRNKHHSPKRHSQTSFPAQKS---------------------------------------TPQSQQLTSTTPQSQQQEASERSESQQIMFLSEPFVRTALVKGSFKTIVQLP-KYVDLGEWIALNVFEFFTNLNQFYGVVAEYVTPDAYPTMNAGPHTDYLWLDANNRQVSLPASQYIDLALTWINNKVNDKNLFPTKNGLPFPQQFSRDVQRIMVQMFRIFAHIYHHHFDKIVHLSLEAHWNSFFSHFISFAKEFKIIDRKEMAPLLPLIESFE-------------------------------------------------KQGKIIYN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : :*. . : . .:* :* ** :* .**:* :. :* :* *..::*: * . * * * * ..::. .*.**:* .:: :: *.*:.:**** . ** *. .::: *:::.*:* *: : : *. * * : *: : :.*:::* ** : * : :: . ", "identical_positions": 44, "similar_positions": 71, "identity": "7.76%" }, { "cls_id": "homologset.agr.SGD:S000001860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499U8-1", "uniprot_id": "TMCO4_RAT", "id": "Q499U8-1", "name": "Transmembrane and coiled-coil domain-containing protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MATWNRPHPRLP---VAPEPVAEGESQQPLGR----------------------------------------------------------------------------------------------------ELSEANRFAYAALCGISLSQLFPEPEQSSFCSEFVTG--LVKWLHLSETVLPTMMAFASG------------------------------------------------------------LGGKGDDIFAQTLLKDPILKDNPS-----------------------------------AISQDLLSFSLKDGHYDARARVLVCHVISLLQVPMEELDILEEVFLESLKDAKEEESETAEESRKRKEKRR--KWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAAT---IIGSAGAAALGS-VAGIAVMTSLFGAAGAGLTGYKMKKRVGAIEEFMFLPLTDGKQLHITIAITGWLGSGRYRTFNAPWMALARSQEQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTLPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEQDCQGIIEDVVLLGAPVEGDPKYWEPFRNVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRMENVDLSSVVNGHLDYAKKMDVILKAVGIRTK-PGWSEKGLPLAPGGLPQEEPLQPATVS-TDETIHQDEQ-----------------------KQGPAPGDSLKSAIPSSASQ---AQVPAGLDQSTEDSLPAAAAPAEGHLVCSHGVGPNPLGCPDCTRETQESCAELD---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WU4-1", "uniprot_id": "TMCO4_MOUSE", "id": "Q91WU4-1", "name": "Transmembrane and coiled-coil domain-containing protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MATWNRPHPRQP---VAPEPAAEDDSQQPLGR----------------------------------------------------------------------------------------------------ELSEANRFAYAALCGFSLSQLFPEPEQSSFCTEFVTG--LVKWLHLSESVLPTIMAFASG------------------------------------------------------------LGGEGADIFAQTLLQDPILRDNPS-----------------------------------AVSQDLLSFSLKNGHYDARARVLVCHVTSLLQVPMEELDILEEVFLESLKDAKEEESETAEASRKRKEKRR--KWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAAT---IIGSAGAAALGS-VAGIAVMTSLFGAAGAGLTGYKMKKRVGAIEEFMFLPLTEGRQLHITIAITGWLGSGRYRTFNAPWMALARSQEQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEQDCQGIIEDVVLLGAPVEGDPKHWEPFRNVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRMENVDLTSVVNGHLDYAKQMDAILKVVGIRTK-PGWREKGLPLAPGSLPQEEPLQTAIVS-TDEIILQDGQ-----------------------SQGPASEDSLKTTIPSSASQ---AQMPAGLNQSTEDSLSTAAAPAEGHLICSHGVGPNPLGCPDCTHGTQESCTELD---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TGY1-1", "uniprot_id": "TMCO4_HUMAN", "id": "Q5TGY1-1", "name": "Transmembrane and coiled-coil domain-containing protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MAMWNRPCQRLPQQPLVAEPTAEGEPHLPTGR----------------------------------------------------------------------------------------------------ELTEANRFAYAALCGISLSQLFPEPEHSSFCTEFMAG--LVQWLELSEAVLPTMTAFASG------------------------------------------------------------LGGEGADVFVQILLKDPILKDDPT-----------------------------------VITQDLLSFSLKDGHYDARARVLVCHMTSLLQVPLEELDVLEEMFLESLKEIKEEESEMAEASRKKKENRR--KWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAAT---IIGSAGAAALGS-AAGIAIMTSLFGAAGAGLTGYKMKKRVGAIEEFTFLPLTEGRQLHITIAVTGWLASGKYRTFSAPWAALAHSREQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEKDCQGIIEDVILLGAPVEGEAKHWEPFRKVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRVENVDLTSVVSGHLDYAKQMDAILKAVGIRTK-PGWDEKGLLLAPGCLPSEEPRQAAAAASSGETPHQVGQ-----------------------TQGPISGDTSKLAMSTDPSQ---AQVPVGLDQSEGASLPAAASPER-PPICSHGMDPNPLGCPDCACKTQGPSTGLD---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43564-1", "uniprot_id": "MIL1_YEAST", "id": "P43564-1", "name": "Probable lipase MIL1", "aln": "MSDSEEDLGVQLKGLKIARHLKESGEHTDEESNSSPEHDCGLSNQDDLTVMHTQAKEEVFKRREEDGTRTEDALHEGEAGKEGTGFPSSQSVCSPNEADSGIDRADKPILLDPFKSVHDTDPVPGTKSRSNSDSDSDSDDGGWQEMPAVSSFNIYNHRGELELTSKVRNSEQASETSPTVPPGKNCKSVNDSRFDYTKMAAEQQAQRSYRTNKKTDFLFDHKVLKKKINSSQTSVNLTSSPSTTSLNNEKNNDDDDDDSYDEYEDDVEPVNDLNRDSQLNITKNLLSDMEKFAYVGAINILANQMCTNLATLCLCIDIKSHKKLAHRLQFTQKDMAAWKTVVLSRLYDHLGISQEEIVMIEKLSLHKIQLEDLCKCLKTTQSIDNPWENDRDHEEDGIEETTERMSPNEQNGSVQASTPDPEQSATPETPKAKQSPLSSDVPGKVLDPENVKSQDKLNIDVAWTIICDLFLICLQSSTYDSRSRTLLINFAKVLNMTSLEICEFERRVTDSLDMEQSTEDQVWDEQDHMRNRRRSKRRKKMAYVALAMVGGSLVLGLSGGLLAPVIGGGIAAGLSTIGITGATSFLTGVGGTTVVAVSSTAIGANIGARGMSKRMGSVRTFEFRPLHNNRRVNLILTVSGWMVGNEDDVRLPFSTVDPVEGDLYSLYWEPEMLKSIGQTVSIVATEIFTTSLQQILGATVLTALISSIQWPMALSKLGYILDNPWNVSLDRAWSAGKILADTLIARNLGARPITLVGFSIGARVIFSCLIELCKKK-ALGLIENVYLFGTPAVMKKEQLVMARSVVSGRFVNGYSDKDWFLAYLFRAAAGGFSAVMGISTIENVEGIENINCTEFVDGHLNYRKSMPKLLKRIGIAVLSEEFVEIEEMMNPEEVKRKRKLINDVDAAQKKLSERKKHNSWVPKWLKPKKSKWKVMVEEAVEEGRDMQDLPENDVNNNENENPDEHEGIARQKRRDAALVDHGALMHELQLIKQAMHEDEIKNKACLPGEDKEVESSNDFLGESHYKPPSTPKINPPQSPNNFQLLSAGRTILPEDDDFDPRGKKKVEFSFPDDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . .* .:* .. * *: *:: ::***.. .: .*: .: .:* :: : *.: *.::: :.: :.. . :. : : .* ** * .: **: :.*:.. **:*:*.*: :. .:*::. *: :*. . :**. :. *.: : . : ::.** : *: :.** ***. *:*::*** **::..* *: ** :**::: : ..* :::: * **.: . *.**:*::. * * ** :.::::: ::::**: ... . . . . . : *.* **.: * .:*:::. : : : . *: * ***:.::::: * :* .:. ::****.*.*.*: ..** **. *::*: * **:**:***:*****: ** *:.::: . *:**:* *:*:*. . : *.*****::***. **:*::::*::: : .. ..: : . :**:: :..*.***:* *.* :** :** . : * : * : :. : : : : :* * : : .. .: : . :: :* .: . : .:.: : : * : : ", "identical_positions": 147, "similar_positions": 251, "identity": "13.69%" }, { "cls_id": "homologset.agr.SGD:S000001861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0P0-1", "uniprot_id": "GWL_MOUSE", "id": "Q8C0P0-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESASASE-ENEGGAAIEE----------CVSRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFVVHLYYSLQSASNIYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMSKPKQDYSRTPGQVLSLISSLGFFTPVGEKDQDSAN------MFSAPKSA---AQLSRGFICPMSVDQKEP--------TSYSSKLLKSCFETLSSNPEIPVKCLTSNLLQCRKRLGTSST-SSQSHTFVSS----VESECHSNPKWERDCQSTESSG--CAMSWNAVEMLYAKSTSAIKTK--------TELELALSPIHDSS--------------------------------------------AIPAAGSNQVTLPRKCF-REISWEARDPDNENMTIDKG---QSGFCQSS----QRSVNSSATSEEHLG--KRNYKRNFHLVDSSPCQEIMQSK---------KNCTEYEANKERQGCRANQSTGLTTEVQNLKLSGCESQQLDYANKENIVTYLTDR-QTPEKLHIPTIAKNLMSELDEDCELSSKKDC----LSSNSVCSDEDR-ALKTTCVDSDSSFPGVSMMESSLEIQALEPDKSIRDYSFEEPNTED----------LFVLPKCQENSLPQDDCHACIQDSSQ-VSAHPSKAPKALTSKINVVAFRSFNSHINASTNSEPSKISITSLDAMDISCDYSGSYPMAVSPTEKGRH--YTSH-QTPNQVKLG-TSYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLGTAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDNAQSAMDMLLTIDDSKRAGMRELKQHPLFSEVDWENLQHQTMPFVPQPDDETDTSYFEARNNAQHLTISGFSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A355-1", "uniprot_id": "D4A355_RAT", "id": "D4A355-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESASGSE-ENEEGAATEK----------CVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQK--GSKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFVVHLYYSLQSASNVYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYTSEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMSKPKQDYSRTPGQVLSLISSLGFFTPVGEKDQDSAN------VFSAPKSE---AQLSQGSICPMSIDQKEP--------VSYSSKLLKSCFETLASNPEIPVKCLTSNLLQCRKRLGTSST-SSQSHTFVSS----VESECHSSPKWEKDCQSAKPSS--TMMSWSAGEMPYAKSVSAIETK--------TDLELALSPIHDSS--------------------------------------------NIPPTGRNYMTLPRKCFSREISWEAREPDINNETMTID---EVSFCQSN----HWAVNSSATSEEHLC--KRNCKRNFHLVDSSPCQEIIQSK---------KNCIEYEANKEKTGCCANQATGLTAQVQNLKLSVCKSQQHDYANKENTVTYLTDR-RTPEELHIPTIAKNLMSELDEDCELSSKKDC----LHSNSVCSDEDR-APKTVCVDSDSSFPGVSMMESSLEIQALEPDKSIRDYSFEEPNTED----------LLMLPKCQENSLPKDDWHASIQDSNQ-MLAPPSKAPKTFASKTNVVAFRSFSSHINASSNSEPSKVSTTSLDTMDISCDYSGSCPMAVTPTEKGRA--CVSHQQTPSQVKLG-TSYRTPKSVRRGPPPVDDGRILGTPDYLAPELLLGAAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDKSQSAMDMLLTIDDTKRAGMKELKHHPLFSEVDWENLQHQTMPFVPQPDNETDTSYFEARNNAQHLTISGFSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GX5-1", "uniprot_id": "GWL_HUMAN", "id": "Q96GX5-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPTAGSKKEPGGGAATEE----------GVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPAN------ILSACLSET--SQLSQGLVCPMSVDQKDT--------TPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATSSA-SSQSHTFISS----VESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGFNK----KDLELALSPIHNSS--------------------------------------------ALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTS-QLGFHQSN----QWAVDSGGISEEHLG--KRSLKRNFELVDSSPCKKIIQNK---------KTCVEYKHN-EMTNCYTNQNTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDCEKNSKRDY----LSSSFLCSDDDR-ASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFEESNIEDP---------LIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNSHINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRS--CMPHQQTPNQIKSG-TPYRTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBX4-1", "uniprot_id": "GWL_DANRE", "id": "Q6DBX4-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAR---------GLACES----------SNS---AVKAPSIEDFVLVKPISRGAFGKVYLARKKCNSKLYAIKVVKKAEMVDKNMTEQMRAERDALALSKS-PFIVHLFYSLQTATKVYLVMEYLIGGDVKSLLHIYGYFDEDMSLKYISEVALALDYLHRHSIIHRDLKPDNMLISNEGHIKLTDFGLSKVKLDR-------------------------------ELNLMDILTTPSLVKPTKDYFRTPGQVLSLISSLGLNTPVIEGKRHSST------VLGSPMSCGKVKQRNRSLGSPLMKRRAEY--------MNSPVCTSRALASNSVFSPVLLARSLTPRLLKSGKRLDTMSVGSTHSCMLPST----TDSENCVSPMWEDEQNLHDVEN---------IPQLNGREVDNRKSR-----------NVPLTPVEKRK--------------------------------------------TLPARAQDHRPVFTPLNNQVTNSRNIKPDLSAKRLQFGAT-DNSATPLEKTVPHQSVGNGLIKPEPLKELKSSVKRAFEEVEKSPEQAEILFK---------KNDAAYERSFQIPEKTSRAHTGLTGIFSIVGLDDVKSAP--------KCQQFNER-TGPKQSSPIAVAKNLFCELEDQGEEGGKAEP----NSSSSTSPGDERNIRRSLSLESDVSAHEMSLVANTPQ-KLSDAKQEVLSSSFEELDENEISAVTPMARPTVATPKHSSAKQRRGECERSLLDHPHGLSDSMIKSPGFLKPK-NVVAFRSYCSSINRSCTS---HLSLASFDAMEMSASAS--FHNAVTPVQKKRPSLSNSLYQTPQQMVVSHTPYRTPKSVRRGPERVEGAPILGTPDYLAPELLLGKPHDFMVDWWALGVCLFEFLTGVPPFNDETPQLVFQNILNRDIPWPDGEE------ELTLNSRNAIEILLTMDTLKRAGLKELKDHPFFDGVDWENLHHQTMPFIPQPDNETDTSYFEARNTAQHLTVSGFSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43565-1", "uniprot_id": "RIM15_YEAST", "id": "P43565-1", "name": "Serine/threonine-protein kinase RIM15", "aln": "MFNRSNTAGGSQAMKEGLGINKLSPISSNSNPSSLTSSNYEKYLQLATEKNPCMILELELDGKVRYGSPQWNTITGVADDSGSSPTYIADLILGSDQDKGVFQKATDMLLMNDDTSCTITFKIKAADYEGSAGCDDESTITTLEARGILIRDGHTQLPSHTMWIVKPRTNDWSDFYANEDAQDDMVIQLSDNCDDIDIQLPEEFAKTLGFGAKIFVQYLKRIRLEMIIDEFNLPLPKMELCRVCENFVPVWWLETHSQSCVCEHRTESLIQLLHDNLLEQQAILANFTKDSEYKGSQIQVRSNNFLNQVLDSLRELCQDAIDINPSEMVPDLYHSLSTFPQDNGNNNNNNNNNNNNNNALLDQFPIQKDTVSLNSYFQFSPRTNHNIQNVTSWQSRFFLNDDQDPGLALLIHDTLDLARKKVDAVLRLDNAMTYSLKIKNEVNNYVVQLIREQIEINKHAILTHPMNLRSSSIFHSPLPQIHSQQPEAENLIYSSSTPLQVQHDQCASFEAPSKSHLEPIPFPVSSIEETPTANDIRHPSPLPRSCSNTVMKLPTPRRKLDSNGLFSDAYLNADIIPNPSIESTISIDRDNNTNSRGSSMKQYGIGEATDSRTSNSERPSSSSSRLGIRSRSITPRQKIEYSHVDNDDRTNEMLSRDKDSLQPQPSVDTTITSSTQATTTGTKTNSNNSTNSVLPKLMTSISLTPRRGSPSFGNLASHSMQQTNSFKLIHDKSPISSPFTFSKDFLTPEQHPSNIARTDSINNAMLTSPNMPLSPLLLATNQTVKSPTPSIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFG--TPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHVYDEEASFVPTIDNPEDTDYFDLRGAELQDFGDDIENDNANILFGKHGINTDVSELSAANLSPPLNHKNILSRKLSMSNTTNRSSNNSNSSVHDFGAHTPVNKLSIASVLESVPQETGYITPNGTGTTTTSAKNSPNLKNLSLAIPPHMRDRRSSKLNDSQTEFGSFNFRNLSALDKANKDAINRLKSEHFSEQPGVHRRTSSASLMGSSSDGSVSTPGSNASNTTSGGK-LKIHKPTISGSPSTFGTFPKTFLRSDSFSTRSYSPERSISIDSSTLSRKGSIIGDNQQTTANSSDSPTMTKFKSPLSPANTTTVSSYFSRQRVLSKSFSQRTNSSDLSAEESDRLQAISRVNSLRNRRRSGRKSSSTSEIGYHMDVLVCEPIPIHRYRVTKDLENLGCTVVSVGAGDELVSRATSGVSFDLIMTALKLPKLGAIDIVQLLKQTNGANSTTPIVAITNYFQEAATSRVFDDVLEKPVKLDELKKLVAKYALKKSQEDEEHTILSDSDETH--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . .***::: ::****:**:*.***.:* .. :*:**::*::*: ** . ::::** : :... *::.:*: *:*. :::*:**** ***: :*::: **: :: : :* :*:.:.:: :*::.***:****:*:**.* **:********:. * * : * :: *. *: . ::* *: . *. . . :. : . ... : : : . . * : : . : . . : :.** . . . * : : :::: .. : : : : . .: . : : .*.. . . . : . : . : . : .. . : * . : . :. : . : * .. . . . . .. : . .. *: : : .. ..: : . :: . : . : .. . ... .: . : : . . . . : . . . .: . : . : * * .. :.. . : : .:: . * : ..:: : * * . . * * *. * : : * ** :... :* .. *. *: *:. * : : :..: :: : :.*. .: . : . *. ::*:: . : : .:* : : : . * ", "identical_positions": 100, "similar_positions": 272, "identity": "5.61%" }, { "cls_id": "homologset.agr.SGD:S000001864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09139-1", "uniprot_id": "AGT1_RAT", "id": "P09139-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAASWVRNMGSHQLLVPPPEALSKPLSIPKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLVGTNGIWGIRAAEIAERIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDILYSGSQKVLNAPPGISLISFNDKAKSKVY--SRKTKPVSFYTDITYLSKLWGCEGKTR-VIHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHLHKCLRELGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSED-KVLRIGLLGYNATTENADRVAEALREALQHCPK------NKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35423-1", "uniprot_id": "AGT1_MOUSE", "id": "O35423-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAAGWVRTMGSYQLLVPPPEALSKPLSVPTRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMLQIMEEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLTGTNGIWGMRAAEIADRIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLVHGESSTGVVQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDIMYSSSQKVLNAPPGISLISFNDKAKYKVY--SRKTKPVSFYTDITYLAKLWGCEGETR-VIHHTTPVTSLYCLRESLALIAEQGLENCWRRHREATAHLHKHLQEMGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFSIEISGGLGPTEE-RVLRIGLLGYNATTENVDRVAEALREALQHCPK------NKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21549-1", "uniprot_id": "AGT1_HUMAN", "id": "P21549-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "----------------------MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNP---LTLVISGSGHCALEAALVNVLE---PGDSFLVGANGIWGQRAVDIGERIGARVHPMTK-DPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--KCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMY--SRKTKPFSFYLDIKWLANFWGCDDQPR-MYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTG-KVLRIGLLGCNATRENVDRVTEALRAALQHCPK------KKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Z3-1", "uniprot_id": "AGT_DROME", "id": "Q9W3Z3-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "---------------------------MEVPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLND---ATMCISGAGHSGMEAALCNLIE---DGDVVLMGITGVWGHRAGDMARRYGAEVHYVEA-SFGRALSHEEITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKY--DCFLIVDTVASLGGTEFLMDEWKVDVAYTGSQKSLGGPAGLTPISFSKRALTRIR--KRKTKPKVYYFDILLIGQYWGCYGTPR-IYHHTISSTLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVDWKKVAEYAMRKYSVEISGGLGPTVE-HVFRIGLMGENATVERVDMVLSILNEAIQSSKLGIKTDLSKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43567-1", "uniprot_id": "AGX1_YEAST", "id": "P43567-1", "name": "Alanine--glyoxylate aminotransferase 1", "aln": "---------------------------------------MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSD-LKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVN-GLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHG-VVIAGGIHKDIGPKYIRIGHMGVTACNKNLPYMKNCFDLIKLALQR------KK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: *** . : * . :* : .*::.: :. : :*:: .: ::*:* . : *.: .. .* .* :. * : **.*. : . * . : : : : . :.: ::**.::. : :.: :: . :::**:*.*:* : :*. :*. :.*** :..*.* : ..: .:: : :: .: : . * . : * :* : **. *:* : :: : **:: : : . : .: : : : * **: : :*** :* .* :. : . : .* ", "identical_positions": 50, "similar_positions": 124, "identity": "11.52%" }, { "cls_id": "homologset.agr.SGD:S000001865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30285-1", "uniprot_id": "CDK4_MOUSE", "id": "P30285-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MAATRYEPVAEIG----VGAYGTVYKARD----PHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTS-----NGTVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPREVSLP-RGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35426-1", "uniprot_id": "CDK4_RAT", "id": "P35426-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MATTRYEPVAEIG----VGAYGTVYKARD----PHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTS-----NGTVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPREVSLP-RGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPLKRISAFRALQHSYLHKEESDPE------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11802-1", "uniprot_id": "CDK4_HUMAN", "id": "P11802-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MATSRYEPVAEIG----VGAYGTVYKARD----PHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTS-----GGTVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP-RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64261-1", "uniprot_id": "CDK6_MOUSE", "id": "Q64261-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDL---KNGGRFVALKRVRVQTSEE---GMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVS-RTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYSFQMALTSV--------VVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP----------------LFRGSSDVDQLGKILDIIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSHLPSNQSTSELNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA87-1", "uniprot_id": "F1MA87_RAT", "id": "F1MA87-1", "name": "cyclin-dependent kinase", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDL---KNGGRFVALKRVRVQTGEE---GMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVS-RTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYSFQMALTSV--------VVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAELFRRKP----------------LFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLHSHLSSSQSTSELNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00534-1", "uniprot_id": "CDK6_HUMAN", "id": "Q00534-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDGLCRADQQYECVAEIG----EGAYGKVFKARDL---KNGGRFVALKRVRVQTGEE---GMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVS-RTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYSFQMALTSV--------VVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP----------------LFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NC60-1", "uniprot_id": "A0A8M1NC60_DANRE", "id": "A0A8M1NC60-1", "name": "Cyclin-dependent kinase 4", "aln": "MAQE----VGLQYEPVAEIG----GGAYGTVYKARD----RDSGQFVALKSVRVQTNQD---GLPLSTVREVALLKRLEQFDHPNIVRLMDVCATL-RTDQETKVTLVFEHVDQDLRTYLEKVPAPGLPVDKIRDLMQQLLCGLAFLHTNRVLHRDLKPENILVTS-----RGQVKLADFGLARIYSCHMALTPV--------VVTLWYRSPEVLLQS-TYATPVDIWSTGCIFAEMFRRKP----------------LFCGDSEADQLGKIFAVIGLPAEDQWPTDVTLS-HHNFSPQSPRPITDCVPDITEKGAELLLKMLTFDPLKRISALNALDHPFFSE------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43568-1", "uniprot_id": "CAK1_YEAST", "id": "P43568-1", "name": "Serine/threonine-protein kinase CAK1", "aln": "MKLDSIDITHCQLVKSTRTARIYRSDTYAIKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMNLYEFMQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWSCQRILQELEKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. . .:*. * * ...:* . :: . : *. : * * *:. *: .:::: * .:: *: : . ::* . .:: *:: *: *** : ::***:**:**::*. : : ***:: : : :. : * *::****: * **:** *::: *:*:. : ..*: : .*: :*:* :.* . * * . :: : .: ..*: . .: ", "identical_positions": 50, "similar_positions": 93, "identity": "13.59%" }, { "cls_id": "homologset.agr.SGD:S000001867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D9I4-1", "uniprot_id": "TBC20_MOUSE", "id": "Q9D9I4-1", "name": "TBC1 domain family member 20", "aln": "MALRPSKGDG-SAGRWDRGAGKADFNAKRKKKVAEIHQALNS---------DPIDLAALRRMAISEGGLLTDEIRCQVWPKLLNVNTSEPPPVSRKDLRDMSKDYQQVLLDVRRSLRRFPPGMPDEQREGLQEELIDIILLVLDRNPQLHYYQGYHDIVVTFLLVVGERLATS---------------------LVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVSPELHDFMQSAEVGTIFALSWLITWFGHVLMDFRHV---VRLYDFFLACHPLMPIYFAAVIVLYREQEVLDC--------------DCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQEAERTAAST------------------FKDFELASTQQRPDMVLRQRFRGLLRPEARTKDVLTKPRTNRFVKLAVMG------------LTVALGAAALAVVKSALEWAPKFQLQLFP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NN82-1", "uniprot_id": "A0ABZ3NN82_RAT", "id": "A0ABZ3NN82-1", "name": "", "aln": "MALRPSEGDG-SAGRWNRGSGKADFNAKRKKKVAEIHQALNS---------DPTDVAALRRMAISEGGLLTDEIRCQVWPKLLNVNTDEPPPMSRKDLRDMSKDYQQVLLDVRRSLRRFPPGMPDEQREGLQEELIDIILLVLDRNPQLHYYQGYHDIVVTFLLVVGERLATS---------------------LVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLLDFRH------------------------VIVLYREQEVLDC--------------DCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQEAERTAAST------------------FKDFELASTQQRPDMVLRQRFRGLLRPEARTKDVLTKPRTNRFVKLAVMG------------LTVALGAAALAVVKSALEWAPKFQLQLFP--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BZ9-1", "uniprot_id": "TBC20_HUMAN", "id": "Q96BZ9-1", "name": "TBC1 domain family member 20", "aln": "MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNS---------DPTDVAALRRMAISEGGLLTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATS---------------------LVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHV---VRLYDFFLACHPLMPIYFAAVIVLYREQEVLDC--------------DCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQQAERTAAST------------------FKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMG------------LTVALGAAALAVVKSALEWAPKFQLQLFP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PCV1-1", "uniprot_id": "A0A8M1PCV1_DANRE", "id": "A0A8M1PCV1-1", "name": "TBC1 domain family member 20", "aln": "--MKKAKKRLPASGSRASVGRHEENLPWKKKKLLDIHQALNS---------DPVDIETLRQAAVSEGGLLTDDIRRKVWPKLLNINVYSLPAKPSKDVREDHKDYRQVVLDVRRSMRRFPKGMRVDEREVLQEQLIDIILDVLRRNPQLHYYQGYHDIVVTFLLVLGERMTIA---------------------IMEKLSNHHLRDFMDPTMDSTKHILNYLMPLLERVDRELHDFMIRSEVGTIFALSWLITWYGYVLSDFRHV---LRLYDFFLASHPLMAIYFAAVIVLYRQKEVKSS--------------ECDMASVHHLLSRMPQDLPYEDLIGRAQSLFSSCPPSQMSRSAALQSR-NILAIST------------------FTDFQTSTRTQRPDSVLRQQIQNRQENQLALPMMPQPTGTNQLIKMAVWG------------LSATLGAAALAVAQTALDWAPEFLSQLF---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43570-1", "uniprot_id": "GYP8_YEAST", "id": "P43570-1", "name": "GTPase-activating protein GYP8", "aln": "MPLRSLFHTNQSSHDKDALTRGGYNAYLESLSRCDSGKAEEQKGKVISKLLEKKDVRALRYIGLGPLGFVNNSLRKDCWYELLASQLLIDDATEYITPVEKHKDEGQVILDAERSFG---GIVDKNLKLQLRKLLVELITRVLRKYPTLNYYQGYHDIVSVFIMCFSWNVTKENGLELENLSLQEEIDMERLFYCIEAFTLLYLRDFMMNSLDFSFEQLRVISSLIKESNMKFYNLFKFDENEPLFAIGSILTIFAHNLKPIDSGDNNLHKILFQIFDMTISMQSMRLPLIIYKNLLLQNASEISKQIEANSDFFENDFDLRHGAIQTVLQKKLYDEALWEEVLQITRKDATTASKKALKRVSLNKYSALLNTACGKPGCFDMSTIIFYLSEQTKMNEHYKEEKYHGVAARSKTRALVQRLGHFLPSKYNRWSKISLLIGIVAILYQLRTTRSLSLVLNLRYMISTKLKDLSHININLHHVSHIWVDPIRDILKLGHPTR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: .. . : :* :. : *: :** .:. *::.:.:* . * :** : . : ** **:**..**: : : : *:: *:::* :* : * *:********* .*:: .. .:: :* :: :***** ::* : . *. : .::.. . :::::: * .:**:. ::* :.: * : :::*:: : .. : *: * :. : *. *: : . : .: ::.* : : : :.: . : : :. . . *: *::: : :* : .: *. ..: :*. ", "identical_positions": 57, "similar_positions": 134, "identity": "11.4%" }, { "cls_id": "homologset.agr.SGD:S000001869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UUQ7-1", "uniprot_id": "PGAP1_MOUSE", "id": "Q3UUQ7-1", "name": "GPI inositol-deacylase", "aln": "------------------------------------------------MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGS---YAEEHKILPLTGIPVLFLPGNAGSYKQVRSIG--------SIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQ----EFAPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMNVNNYWILN-------------------------------ARHIN-LTTLSVAGGFRDYQVRSGLTFLPKLSHYTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKP-KKKLSVLNHHFIR----------HPAKQFEENPSIISDLTG-TSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKIYTHAYCQSTMLDTNSWIFGCINST------SMCRQGVD-------LSWKAELLP---------TIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSMQLPVTHLFSFGLSSRKVTLNTNGLYYN----IELLNFGQIYQ-AFKVNVVSKCTGSKEEITSIYKLHIPWSY----------EDSLTIAQVPSSTDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTG--YCLEYSTILDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLT---------SQSMCFP-LVSLILFLFGTCTAYWSGLLSSTSVQLLSSLWLALKRPAELPKDIKVMSPDLPVLTVVFL-IVSWTTCGALAILLSYLYYVFKVVHLQA---SLTTFKNNQPVNPKHSRRSEKKSNHHKDSAVQS------LRLCANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWLKNLRYYFKLSPDPCKPLAFLLIPAIAILGNTHTVSVKSSKLLKTVS------QFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHALCNFM----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q765A7-1", "uniprot_id": "PGAP1_RAT", "id": "Q765A7-1", "name": "GPI inositol-deacylase", "aln": "------------------------------------------------MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGS---YAEEHKILPLTGIPVLFLPGNAGSYKQVRSIG--------SIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQ----EFPPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMTVNNYWILN-------------------------------ARHIN-LTTLSVAGGFRDYQVRSGLTFLPTLSHHTSALSVVTSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKS-KKKLSVLNHHFIR----------HPAKQFEENPSIISDLTG-TSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKVYTHAYCQSTMLDTNSWIFGCINST------SMCRQGVD-------LSWKAELLP---------TIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSIQLPVTHLFSFGLSSRKAIINTSGRYYN----IELLNLGQIYQ-AFKVNVVSKCTGGKEEITSIYKLHIPWSY----------EDSLTIAQVPSSVDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTG--FCLEYGTMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLT---------SQSMCFP-LVSLILFLFGTCTAYWSGLLSSASVQLLSSLWLALKRPAELPKDVKVMSPDLPVLTVVFL-IISWTTCGALAILLSYLYYVFKVVHLQA---SLTTFKNNQPVNPKHSRRSEKKSNHHKDSAIQN------PRLSANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWSKNLRYYFKLNPDPCKPLAFLLIPAIAVLGNTHTVSIKSSKLLKTAS------QFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHSLCNFM----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q75T13-1", "uniprot_id": "PGAP1_HUMAN", "id": "Q75T13-1", "name": "GPI inositol-deacylase", "aln": "------------------------------------------------MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGS---YAEEHKILPLTGIPVLFLPGNAGSYKQVRSIG--------SIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKTILKLYKGQ----EFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLITQATPHVAPVMPLDRFITDFYTTVNNYWILN-------------------------------ARHIN-LTTLSVAGGFRDYQVRSGLTFLPKLSHHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNS-KKKLSVLYHHFIR----------HPSKHFEENPAIISDLTG-TSMWVLVKVSKWTYVAYNESEKIYFTFPLENHRKIYTHVYCQSTMLDTNSWIFACINST------SMCLQGVD-------LSWKAELLP---------TIKYLTLRLQDYPSLSHLVVYVPSVRGSKFVVDCEFFKKEKRYIQLPVTHLFSFGLSSRKVVLNTNGLYYN----LELLNFGQIYQ-AFKINVVSKCSAVKEEITSIYRLHIPWSY----------EDSLTIAQAPSSTEISLKLHIAQPENNTHVALFKMYTSSDCRYEVTVKTSFSQILGQVVRFHGGALPAYVVSNILLAYRGQLYSLFSTG--CCLEYATMLDKEAKPYKVDPFVIIIKFLLGYKWFKELWDVLLLPELDAVILT---------CQSMCFP-LISLILFLFGTCTAYWSGLLSSASVRLLSSLWLALKRPSELPKDIKMISPDLPFLTIVLI-IVSWTTCGALAILLSYLYYVFKVVHLQA---SLTTFKNSQPVNPKHSRRSEKKSNHHKDSSIHH------LRLSANDAEDSLRMHSTVINLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMAILGNTYTVSIKSSKLLKTTS------QFPLPLAVGVIAFGSAHLYRLPCFVFIPLLLHALCNFM----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSV5-1", "uniprot_id": "A0A8M9PSV5_DANRE", "id": "A0A8M9PSV5-1", "name": "GPI inositol-deacylase", "aln": "-----------------------------------------------------MRLVVYAFFAFALGLLLVGLRELLFGFEENRCSMTYMFEYPEYRRVQLPRRVARQYPSYGLYLYGEGA---YAQETRGLKLTGAPVLFLPGNAGSYKQARSLG--------SVALRKAENLERQIHLNVFTIDFNEELVALYGGSLRRQTQFLHESIKAILRLYEDR----PDPPTSVVLVGHSMGGVVARALFTLARFHPRLVSLIITQASPHQAPVLSLDPYILEFYSTVRQGWNKR-------------------------------AEDLRNVTVLSVGGGNLDFQVLSGLTALSCPIDDLNKISVVATAVPRTWLSTDHISIVWCKELVLATVRAFFDLIEPETGQFTESP-EERLSVLNYHFFR----------HPVLPPGEVQGASVTFSAPPEAWKEVNTLRLFYSAPKEAQVKYFLFGLSSRRKAYSHFYCRSNNMEMTSWLYGCTQMSG-----SMCVQAVD-------LSSDTELLP---------AYKTVAVKISKLMSVSHLIIDASNPSGAQFVVECELQREESLTVSVQVPHLLSFGLTVTDVSINSSGLLHT----LQLQDFHQVYQ-AFRITIMSHCKTNKDRLPSVYRVSVPWFR----------EDSFAMSSTPSVSEIFSMLHSSRPDN-TSSAMLQLHTAPNCQYKVSIRTSFPKVLGQILRFCGPLLPVYCALALLLMIRVQLSSVRRSG--RPVELQEAMSKSLEIHKLELPVLLLMLLLRQSWFQDVWTSLGLPGVDALPLNTVEDLSHEKASVQEWPRLVSPLLCVFGAAIAFWGSTVLRMSVCFLSFIVAPLHRPS-VSRDCGTFGLHTQIVMMVSLGVLGSLTCGSLALMLCCLLHLYRVLRLQMTERSLSHMLNLAPQKASHNTENGFNGNDHHSNGKECNGSALLSESVLQDVRDDLQLHLSVSTVLTLTMMLCAPSLIHWKHNLRYWLHLDPDPCWPHTVPLLISSVLLINCNTNSLLRSKLMLNLTL-----RLLLPLCVGLLAFCPLHIYRVTHFLSAALSLLVCSCYF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W495-1", "uniprot_id": "PGAP1_DROME", "id": "Q9W495-1", "name": "GPI inositol-deacylase", "aln": "--------------------------------------------------MFMFRNCAVLLVIGSICCFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGVRD--GDQYPNYALYYYYEGLR--QPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLA--------SVALRKAMSNDAGIHLDYYTIDYDEELSALYGGYLHRQQSYLKLCIRTILSIYEGR----TEQP-SIVLIGHSMGGKLAQSVLVDPAIG-QHINTIISISTPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTMTTNVCDSLHQRPPSVQRMASQDSSARLDNVLLISTGGGNRDLLVRPGLTSS-----RFNDLHAMTSAIPKVSLSCDHLSAVWCLQFMQAINRFLFSVAYVREDRSSIAFGTNKQRNLQTALST----------FVKPRRRQQNTVRFGAAG---NWHEERRLVINKYFTNGLKGTFFDLIGLQRQERYRKAAIEALNVDDEDWLFGCSAEDNNKTGQLYCEKATS-------LMHLVQWLPNEDREPRSIALLDLHNLRKTYVHWTHLLVRLP-PSAKRIGYNLDIYDPKERVTDIKMPRWYTMAKLPLINETLQGTLHHR----VRISEMVDPYQ-SIRV-IVEPLQCINPEYRVTARICVPWAAGFERF-----QTLKSFDQKPQLYVNVPTLVPRHYNTTLNPVTLELYLDPTCRYRISYEYSYSSALSRLVLEFYGWLPAHLVCVLLIVLRKQVETFYDVGTFRSLRPYVGYLQYTSLYIVTACRLLKKLIISSRVFPEPEPLDYSINVSIVIHCA--------AIALSLLATLGTWLALTLYGNAFYR-LALRITRLSQATSNVMISIMTHLPITYGILTIATAMGTCSGVGLLLAFVFYFLMLSNAYKDYLEDFLWQKAAN-LVRGKPSAVTEQEDATEEQNEEQNALKQNDEQKQQQQEEEEPEACVGLQNFSFHVTLLLMLFVQLLLNAPSSLAWLRSRRHGINL-PDPSLYPSIVVLASLSLLLQLRAPQKCQGYWMLSIA--------FYILAGVVLLYCQAAIYRLTYVIAGAFALLSAHQSLWILWGRVSRV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43571-1", "uniprot_id": "BST1_YEAST", "id": "P43571-1", "name": "GPI inositol-deacylase", "aln": "MGIRRLVSVITRPIINKVNSSGQYSRVLATREDQDKASPKYMNNDKIAKKPYTYRLFSILGILSICSLLLISLLKPFNGADAPQCESIYMFPS-YARIDGFDERYTPLAHKYHLYLYREQSVDREPLNGDELQLDGIPVLFIPGNAGSFRQCRSIASACSNIYFDSNTRATLRNENVRNLDFFTADFNEDFTAFHGETMLDQAEYLNDAIKYILSLYERTPDYPHPKPQSVIIVGHSMGGIVSRVMLTLKNHVPGSISTILTLSSPHAASPVTFDGDILKLYKNTNEYWRKQLS--------------------------QNDSFFSKNISLVSITGGILDTTLPADYASVEDLVSLENGFTSFTTTIPDVWTPIDHLAIVWCKQLREVLARLLLESIDASKPE-KVKPLNQRLQIARKLLLSGFEDYSWMNSKLNYPQENLQEFSDNFFSDYATLEMNDVLDFEMFNLEKWHNNYTKINIPSNISSTEHLHFTLLTSLDMPMIYFCTESRVN----LSCITAVDSILTVPRSSKDTQFAADSSFGEAKNPFKAVSVGKNILQKYDYLMISKPTYGEFSEQEGMEDNQGFLLALLRNVSNVQIVNTTPSQILLFGEQLHLDGKDIEQVISFSNLWDSLLSYKLETKIEASNEGIASEETLFQPFIRQWVYEPFESKWHLNIINKSLDINMHNVAPFIPLNESEPRSLQLSFFIPPGMSLEAKMTINWSLTLKMLFIRYRLALASFPVAFIALVLSYQFYWYNKTSEFPSFDSTLGYILRKHGILMFFTLFLASPVVNNKLVQRILYLLDPVGLNYPFLLS-----------ERNMHANFYYLGIRDWFMSTIGILFGVMTVGLLALVSKIFGSLEILVIFLQRKLSKKNTEDKEAFDTIEHKAYGKGRLMASVLLLLLVFFHIPY---QMAFVISLVIQIATCIRVALLKLSNNEQK------------------LNLLNYNMTLLLLLLFVSAINIPIIIVFLHN--VAIKWETSFRSHHNILAVAPIIFLVGNNSIFKMPNSVPLDTWDGKVTIILFVYLTVFSFIYGIRNLYWIHHLVNIICAWLLFFETIH---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* : * *** . * ** * * . : : * **:*:******::* **:. . * : : ::: :: :::*:: *::* : * .::: .*: ** :*: * *: ::****** ::: ::. :. ::: ::* . : :* : .:* . : : :* ** * : .. : . : .::::* . . **:: *** :: . * ::. . . :: : : . : . : : .. . : :: * * ... .: . . : . :::: . : :.. . .: .: : :: : : : : *: : . . :. :.:. . . . .:. * :. *. . . : : *. . . : :: :: . :. * : : : : : : . : . : . : .. : . : . ... : : : :: :* : * : : :. :: .. . : . .* : . * : : :* : .: : ", "identical_positions": 66, "similar_positions": 214, "identity": "5.98%" }, { "cls_id": "homologset.agr.SGD:S000001870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG5-1", "uniprot_id": "D4ADG5_RAT", "id": "D4ADG5-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPP---QPTPETVPVINKSDIKQYDFQS----------SDEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------CTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJU0-1", "uniprot_id": "A0A8I6AJU0_RAT", "id": "A0A8I6AJU0-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKNESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEVKPL---QFEIMIDRLEKASSN------------QLVTLQEAELLLNEDDYLIKAVYDYWVRKSKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPP---QPTPETVPVINKSDIKQYDFQS----------SDEDEFPQVPSPSSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCKSSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------YTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0I4-1", "uniprot_id": "EPC2_MOUSE", "id": "Q8C0I4-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAGIAPQ---QPTPETLPVINKSDIKQYDFQS----------SDEDEFPQVLSPASEAEEENDPDGSCAFRRRAGCQYYAPRLDQANNHMCENSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGFS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------CTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLVQMQRQQLAQLHQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGLAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52LR7-1", "uniprot_id": "EPC2_HUMAN", "id": "Q52LR7-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRS-EKELY----------------------------------------------------ATPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQ---QPTPETLPVINKSDIKQYDFHS----------SDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQAN-HSCENSEL-----ADLDKLRYRHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNSFS-SSSQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEE-------CTSRKPGQTVNNKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C9X6-1", "uniprot_id": "EPC1_MOUSE", "id": "Q8C9X6-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFRMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPL---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGSSLIPLVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY----------------------------------------------------AIPIIPITNSSQFKHQDATDSKEFKVNKQDKA-DLIRPKRKYEKKPKVLPPSAAA-PQQQSPAALPGFSAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCLGFARRRVGRGGRVVLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSEPNTSDRSSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE-------LSSRKLHRSISRAGAAQPGAHTCSTSTQNRSSSGSAHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQQANSSSSAAAQ----------------------------------------------------------------------------------QGFVSKTLDSASAQFAASALMTSEQLLGFK-VKDDVVLGLGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSSLSHQVTAASSATTQVLFGNNIRLTVPSSVPTVNSVTPINARHIPRTLSAVPPSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G2P8-1", "uniprot_id": "A0A8I6G2P8_RAT", "id": "A0A8I6G2P8-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPV---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY----------------------------------------------------AIPIIPITNSSQFKHQDVTDAKEFKVNKQDKA-DLIRPKRKYEKKPKVLPSSAAA-PQQPSPAALPGFSAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSETNTSDRPSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE-------LSSRKLHRSISRAGPAQPGAHTCSASTQSRSSSGSTHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQ-ANSSSSTAAP----------------------------------------------------------------------------------QGFVSKTLDSASAQFAASALMTSEQLMGFK-MKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSALSHQVTAANSATTQVLFGNNIRLTVPSSVPTVNSIAPINARHIPRTLSAVPPSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2F5-1", "uniprot_id": "EPC1_HUMAN", "id": "Q9H2F5-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPL---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKNCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYNGEIMSEVMAQRQPMKPTY----------------------------------------------------AIPIIPITNSSQFKHQEAMDVKEFKVNKQDKA-DLIRPKRKYEKKPKVLPSSAAATPQQTSPAALPVFNAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEDNDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCIGFARRRVGRGGRVLLDRAHSDYDSVFHHLDLEMLSSPQHSPVNQFANTSETNTSDKSFS-----KDLSQILVNIKSCRWRHFRPRTPSLHDSDNDE-------LSCRKLYRSINRTGTAQPGTQTCSTSTQSKSSSGSAHFAFTAEQYQQHQQQLALMQKQQLAQIQQQQANSNSSTNTSQNLASNQQKS------------------------------------------------------------GFRLNIQGLERTLQGFVSKTLDSASAQFAASALVTSEQLMGFK-MKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSALLQPSNITQTSSSHSALSHQVTAANSATTQVLIGNNIRLTVPSSVATVNSIAPINARHIPRTLSAVPSSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U369-1", "uniprot_id": "A0AB32U369_DANRE", "id": "A0AB32U369-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESLYPGDFKMPKQLIHIQPFSLDTEQPDYDLDSEDEAFVNKLKKKMDVGAL---QFEEMIDRLEKGSGQQMLLSKATCIALKPVTLQEAKLLLKEDDELIKEVFEYWSKKRKTCQSGSLIPVVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIVEKRNNMSDFGGEVMAEVLAQRALEKP------------------------------------------------------VIPLIPITNSTQYRHTEHD--RDYKI-KMDKP-EVVRQKRKYEKKPKPLPLAGSV------HSGPSVFNTKDLNQYDFPS----------SDDEPFSQMFSGSSEVEEENDPDGVFGFRRRTGCQYHSARSGPVSGWPWSDPAE-----GGVADVRYRYSLTTLTVPR-RCLGLARRRVGRGGRVLLDRAHSEWDTVYHGLDPDSPAFPSLSPTQQQPSTDTSHTSTDTSAPSATPPDLTQILLNIKACRWRHFKPRTAPPDDPDNPEH------WSTRRPRRGFLIRPIRTLQTQRGPASIRPPPPPPTP--AFTAEQYQQHQEQLVLMQKQQLEQVQQHQQTGSSAVTNNP----------------------------------------------------------------------------------QSLVSKTIDAASAQFAASALVTHEQLLALK-SKDE---GVGVNGVVSASGVYKGLHHTSSAVSSILPSVGSTS-TSCPSPTIATTTNNGTSSANHHVGPAGPAPGQALMGGAVRVSVPSPAGTLS------VRQLQRQLT-VPASALKLAANAN--RPLPKVTTGSTTLDMG-----PRENHDQEKPPLNSLTENTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFP2-1", "uniprot_id": "A0A0B4KFP2_DROME", "id": "A0A0B4KFP2-1", "name": "Enhancer of polycomb-like protein", "aln": "-------------------------------------------------MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICTGLIIPTP--------EVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQQ-QRLELTEL---KFEQMMDRLEKSSGQ------------TVVTLNEAKSLLNQDDETSISVYDYWLNKRLKMQHP-LILTVKTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRREETKRDHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILAALPTGLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQQHQQQQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAANDSIADSEEEDYFGAGAQNGNKLGSESEEETPFAFRRRSSCVYLPTR-QRDGRYPWDSADEDMAPSGACSDAKYRYTLTSLNYPRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMESVTVNKCRDKIKQRDPDQLCKPSSP----PTVVDLVPAGKPVDGEHPVPELIKEEPSSDTEKPVAATESGRESKERELEEKFENDVDDEFVASDDENVSRLGIYSSAVTLPQSCADLRQKRRRLRRKKQQLRELNAAKRLKRSSEAVATAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQKLKVEEDDNTEVSENVAPELLEMNDPEQLQPPRANHQQHHRSNHNNNNNTVLNNNNSSSSNVMNKDVSISEKINVIKQEAEELVGGKCEDQPVASTSAAAAAARAAEAAAAAEAASSTTTLAAPNPGPSLEEVAKTIKREMIDADDSNEPLSSIRT-AAVMLSTQTSVSELMDDEAEDDVNLAQLSSIIRHTAVKKELEAQQHQQQVQHEQMQAARKMEEDEAAPCLNQLPDVIRLRNIRNSQVHARPKDLFVQAPVDEEFNADYMGGLSPTSSQRLDICNELLSEIRRDWLHFRPKTPTDELSDSQDCEVGKTCDSHAVDWTQDTPISVELNRLGKREAEESDSSSYFLSSGFKYRDLESDAQLLQTVQAQDYARGSSKSPNCSGSGSGSALEFNLSGGDSLNDINNLLGCDDEDDNHEHMLDNILQECAMDDPKALNQATNFWNGILDGEAAVDEVEMADQLLDCIDEKKSKVGAADTSKRAGRNRKARLIQAPVGSSAFTVCPTAETLKERELFFSQAPPVEVPPKEKTPAEVELPEVVVKETANLPVKVEAVEKPQSEVLPVAPQPQQLQPQAITLPTTQLINIPAQISTQKQHQQPQVTQLLNQFANAGPQIIARTEYGGGAAVGDIVTITPHTGSSPLPTLTAQQQLQHQLAQAQLRNVTVQQRQATPQNPNQNQNPQQQLLFQMQRDPSRSLTPLQAAGAGATGNHLIYTTSCGEIVTAGAAASASQKVTYAIQKAGVSSGGATTASIGPNTVITLSNVKVQNDDISSGGSGNSGSSVNIINTASGQQLAVHSIAGMQQQGQQQVQQVTTSTPLLVATPTRNNVQQQQQQLVQQQPIVWRQVSGTNTAVATTAVLSTTVDSSPKAVTNQILWTSRATQKRQLNGPENTDINKLLLNRKLPRKQQIQQQHQQIQLTKQQLQQLVQHEELDDLVATSTGNSGDQMETGDGLQQQQQQQQQQQQLQKLSKVIKMSQFPLLVSDVSLQQQQSVSGQAQQQQLKPNSAAAIAANHNYSLHPASTAIITAQATPQQANKIFLTSSNSGGGGSAGNFTIATASELQAAAAGQKLHYKELPNSNLKLNFVSSAGTGEQTQQVGATTVLLNKSQQQQQQQQHQKLKTLATTGNSQTGQGDKRVLYTSLLNVKPLQKNNSGQMQMQLGPGGLQQVLRGRLNNSAIITRTLPLGTTVNSTGGAVGPTTTTIRQLVTTNANNVSSQDGNLLSAKEVGKALTVEQVIASANNGGVVLPTSNNNNNNNGSGAGGNGGPLNSGVNATGAGGGGSTGAGVGGAGVTSTINRXDADGSGSNSXHRAQPLQVPNGPLLSLASTQTEAETQAVAISMPLADAHVALGQLLQQHHCSCTVCLVNKSELV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43572-1", "uniprot_id": "EPL1_YEAST", "id": "P43572-1", "name": "Enhancer of polycomb-like protein 1", "aln": "MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMG--SGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMD--PESILSFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQ-RLRALHQELKNAKDLALLVAKREN----------------------------------------------------VSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQ----------LEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQ-LANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEK-------RKIEDADVFFNLTDDPFNPVFDMSLPKNFSTSNVPFASIASSK--------FQIDRSFYSSHLPEYLKGISDDIRIYDSN--------GRSRNKDNYNLDTKRIKKTELYDPFQEN---------------LEIHSREYPIKFRKRVGRSNIKYVDRMPN--------------------------------------------------------------------------------------------FTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDS------PQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLK----------QKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSN-----SLKKLNDSLINSEAKQNSSITQKNSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** * :. : : :: ::: .* . :* * :: :*:**:**.* **:* : . *: * .:: . . *::.. * .:*::*. ** :.. .: . : :** : . :*:. : ::::* : * :.* : : .: . : : .. . : * : . .:: : : . **:.* .: : **.: :: :::.:.: .: : : . . : . ::: .. . ::. . .: .:.: : .:: . . . . . . . : *. . .. :.:.:: : * : * . * . . . :: . . : . . . .: ::: : . . .::.: . : : : . : : : : . : . . : . . :. : . . ", "identical_positions": 40, "similar_positions": 187, "identity": "1.84%" }, { "cls_id": "homologset.agr.SGD:S000001871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTZ0-1", "uniprot_id": "UXT_MOUSE", "id": "Q9WTZ0-1", "name": "Protein UXT", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKRRALDTVGEKVLRYETFISDVLQR----------------------DLQKVLDHRD---------------------------------------------KVYEQLSVYLQLRNVIERLQETNHSELYMQVDLGCNFFVDTVVP--------DTSRIYVALGYGFFLELTLAEALKFIDRK-----------SSLLTELSDSLTKDSMN----------------------------------IKAHIHMMLEGLRELQG------LQNFPEPSPH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63ZY7-1", "uniprot_id": "UXT_RAT", "id": "Q63ZY7-1", "name": "Protein UXT", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKRRALDTVGEKVLRYEAFISDVLQR----------------------DLQKVLDHRD---------------------------------------------KVYEQLSVYLQLRNVIERLQETNHSELYMQVDLGCNFFVDTMVP--------DTSRIYVALGYGFFLELTLAEALKFIDRK-----------SSLLTELSDSLTKDSMN----------------------------------IKANIHMMLEGLRELQG------LQNFPEPSPH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBK9-1", "uniprot_id": "UXT_HUMAN", "id": "Q9UBK9-1", "name": "Protein UXT", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKRRAVEATGEKVLRYETFISDVLQR----------------------DLRKVLDHRD---------------------------------------------KVYEQLAKYLQLRNVIERLQEAKHSELYMQVDLGCNFFVDTVVP--------DTSRIYVALGYGFFLELTLAEALKFIDRK-----------SSLLTELSNSLTKDSMN----------------------------------IKAHIHMLLEGLRELQG------LQNFPEKPHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43573-1", "uniprot_id": "BUD27_YEAST", "id": "P43573-1", "name": "Bud site selection protein 27", "aln": "MDLLAASVESTLKNLQDKRNFLSEQREHYIDIRSRLVRFINDNDDGEEEGEGQGMVFGDIIISTSKIYLSLGYEYYVEKTKEEAITFVDDKLKLMEDAIEQFNLKIEEAKKTLDNLNHMEDGNGIEEDEANNDEDFLPSMEIREELDDEGNVISSSVTPTTKQPSQSNSKKEQTPAVGPKEKGLAKEKKSKSFEENLKGKLLKRNDEVKKKVQPSKVDTENVYTFADLVQQMDQQDELEDGYIETDEINYDYDAFENSNFKVNDNYEEDDEDEDEEEYLNHSIIPGFEAQSSFLQQIQRLRAQKQSQDHEREEGDVNKSLKPILKKSSFAENSDKKQKKKQVGFASSLEIHEVENLKEENKRQMQSFAVPMYETQESTGIANKMTSDEFDGDLFAKMLGVQEADEVHEKYKEELINQERLEGEASRSNRRTRVSRFRKDRASKKENTLSTFKQETTRSVENEVVEKEPVVGDIIEKEPVVGDVIEKEPVVGDVIEKEPAVTDIVEREPAVNDIVERKPVVGDIIEKEPTINDIVEKEPEINSKSEFETPFKKKKLKSLQKPRSSKSMKKKFDPKILENISDDDYDDDDDGNKKLLSNKSKNNTDEQDKFPSKIQEVSRSMAKTGATVGSEPVRITNVDYHALGGNLDDMVKAYSLGLYDDDLEEDPGTIVEKLEDFKEYNKQVELLRDEIRDFQLENKPVTMEEEENDGNVMNDIIEHEFPESYTNDEDEVALHPGRLQEEVAIEYRRLKEATASKWQSSSPAAHTEGELEPIDKFGNPVKTSRFRSQRLHMDSKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. **.:.: :. * : ..:*:* ** : :*::* .: : .: : *:**: ::*: : : : . * :..:: *..: :*:. **: .* ** ::: :. * :::.:*.*.:: ::: : :. :*: :. *..* : . : ", "identical_positions": 28, "similar_positions": 73, "identity": "3.52%" }, { "cls_id": "homologset.agr.SGD:S000001872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q505J8-1", "uniprot_id": "SYFA_RAT", "id": "Q505J8-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "MADNPVLEQLLRRLEVADGGLDSAELATQLGVEHQAVVGAVKSLQALGEVIEAELRSTKCWELTTEGEEIAREGSHEARVFRSIPLEGLVQSE--LMQLP--SGKVGFSKAMSNKWIRVDKS---AADGPRVFRVVDSIEDEVQRRLQQVQA-GQAEKLAEKERNELRKRKLLTEVILKTYWVSKGKGFSTSVSKQEAELSPEMISSGSWRDRPFKPYNFSARGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLP-MDYVQRVKRTHSQGGYGSQGYKYTWKLEEARKNLLRTHTTAASARALYRLAQKKP-FTPAKYFSIDRVFRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRLDIEPRSSKTQEAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0C7-1", "uniprot_id": "SYFA_MOUSE", "id": "Q8C0C7-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "MADNPVLELLLRRLEVADGGLDSAELATQLGVEHQAVVGAVKSLQALGEVIEAELRSTKCWELTTEGEEIAREGSHEARVFRSIPLEGLVQSE--LMHLP--SGKVGFSKAMSNKWIRVDKS---AADGPRVFRVVDSIEDEVQKRLQLVQA-GQAEKLAEKERNELRKRKLLTEVILKTYWVSKGKAFSTSVSKQEAELSPEMISSGSWRDRPFKPYNFSARGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLP-MGYVQRVKRTHSQGGYGSQGYKYTWKLEEARKNLLRTHTTAASARALYQLAQKKP-FTPAKYFSIDRVFRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRLDIEPRSSKTQEAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y285-1", "uniprot_id": "SYFA_HUMAN", "id": "Q9Y285-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIPPEGLAQSE--LMRLP--SGKVGFSKAMSNKWIRVDKS---AADGPRVFRVVDSMEDEVQRRLQLVRG-GQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLP-MDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKP-FTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPLCRLDAEPRPPPTQEAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPX3-1", "uniprot_id": "SYFA_DANRE", "id": "Q1JPX3-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "MADTGLLEALLQRVEQLDGGVDSQDVSAALGVDHQLVVGAVKSLQALGEVISAEQKSSKHWELTGEGREIAEQGSHEARVFNAIPAEGLPQNQ--LMKMA--SGKVGFSKAMSNKWIRLDKA---HEGGPRVFRTVESIEDTVRDKLQLVQN-GQSAKLEEKEKNELKKRKLLAEVTVKSYWITKGNSFSTTITKQETELTPEMIASGNWKEKKFKPYNFEAMGVAPDCGHLHPLMKVRTQFRQIFLEMGFTEMPTNNFIESSFWNFDSLFQPQQHPARDQHDTFFISDPALAHEFP-RDYLERVKKVHSEGGYGSQGYKYDWKIEEAQKNLLRTHTTAVSARMLYKLAQQEK-FTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADYGLTLGNLMGVLHQFFTKLGITKLRFKPAYNPYTEPSMEVFSYHEGLKKWVEVGNSGVFRPEMLLPMGLPEGVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPICRLDS-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3J5-1", "uniprot_id": "SYFA_DROME", "id": "Q9W3J5-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "-MHPDLTERILQHLETTDK-ADTLDLAALFAEDHQKIVGSLKSIQAHGELVTAETVTHKSLGLTDEGRAVVENGSHEALVYDLVPPEGIAQAA--LMAAGGANAKVGFSKAMSHGWILVDKS---VTP-PLVRRKVDTITDVVRNQLQQVAL-GKGDQLPAKEVADFKKRKLLQETTTKSFVLARGPEFATTLTKLETDLTVEMLANGLWDQLKFKAYNFDALGAPPTRGHLHPLLKVRTEFRQIFLEMGFSEMPTNNYVESSFWNFDALYQPQQHPARDAHDTFFVNHPAKSHKFP-QDYLERVKKVHSVGGYGSKGYGYDWKLEEAQKNLLRTHTTAVSARMLYKLANQEGGFKAAKYFSIDKVFRNETLDATHLAEFHQVEGVIADVGLTLGDLIGTLYEFFRKLGITQLEFKPAYNPYTEPSMEIFCYHPGLAKWIEVGNSGVFRPEMLLPMGLPENVNVIAWGLSLERPTMIKYGINNIRDLVGPKVDLKMVEEGPICRLDHA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15625-1", "uniprot_id": "SYFA_YEAST", "id": "P15625-1", "name": "Phenylalanine--tRNA ligase alpha subunit", "aln": "--MSDFQLEILKKLDELDEIKSTLATFPQHGS--QDVLSALNSLKAHNKLEFS-KVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVGKVGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAKILNDLKKRKLIAQGKITDFNVTKGPEFSTDLTKLETDLTSDMVSTNAYKDLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALYVPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKLVLRTHSTAISARMLHDLAKDPK---PTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNITLGDLIKFMEEFFERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEMLESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGHKVSLDFIETNPAARLDEDLYE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:::: * .: . . * ::.:::*::* .:: : ** ** : .:**:* : : * * : .*** ::*:.: ** : : :: : * .: * : .: .: * :::****: : . : :::* *:* ::* *::*: :*::.. : : **.*** : *. * **** *** :*****:.***:***:::::*:.*****:*: ******** :***:: .* : *::.:* .*. * :** ** * ** :*.:* :****:*: *** *: **:. ..: ****:*****::**********:***:** .:***.*: : :** ::*:* *.***:**********:*.:* ** **:*:****:****** .****:.: *:.************* ::***:*:* **.*.:: .* .*** ", "identical_positions": 195, "similar_positions": 148, "identity": "37.64%" }, { "cls_id": "homologset.agr.SGD:S000001873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNA5-1", "uniprot_id": "A0ABZ3NNA5_RAT", "id": "A0ABZ3NNA5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAQS-----------PGQ--GTYAD--SGPFLHSSG--------AGSPVFVAPTRVPSMLPYLPS------CEPGSQPPALAAHSSWTQAVSAESSAFG----------SGSPHPPATHPPGATAFPFAHSP-------------SGSGSGGSAGVRDGAAFQSALLARE-QYPTA-LGRPMSASYPTTY---------------------------PAYVSPDVAPSWTSGPFDSS------------------------------ILHGLQGRPGGLPGRRTTFVPDFLEEFPGEGRECVNCGALSTP-LWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLLSFTAPEAPKSRVPNFWAHPSLLAPQSSSRRSGLCCSNCHTATTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANSTASSPTLLNTESSATTLKAES--SLASPGCAGPTITSQASSPADESLASSHLEFKFEP-------EDFVFTSSSLSPQAGLSG--VLRQEAWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97489-1", "uniprot_id": "GATA5_MOUSE", "id": "P97489-1", "name": "Transcription factor GATA-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAQS-----------PGQ--GTYAD--SGAFLHSSG--------TGSPVFVAPTRMPSMLPYLPS------CEPGSQAPALAAHSSWTQAVAADSSAFG----------SGSPHPPAAHPPGATTFPFAHSP-------------PGSGSGGSAGVRDGGAFQGALLARE-QYPTP-LGRPMGASYPTTY---------------------------PAYMSSDVAPSWTSGAFDSS------------------------------ILHGLQARPGGLPGRRTSFVPDFLEEFPGEGRECVNCGALSTP-LWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLS--------------------------SSRRSGLCCSNCHTATTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANTTASSPTLLNSESSATTLKAES--SLASPVCAGPTITSQASSPADESLASSHLEFKFEP-------EDFAFTSSSMSPQAGLSG--VLRQETWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWX5-1", "uniprot_id": "GATA5_HUMAN", "id": "Q9BWX5-1", "name": "Transcription factor GATA-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAAS-----------PRQ--AAYAD--SGSFLHAPG--------AGSPMFVPPARVPSMLSYLSG------CEPSPQPPELAARPGWAQTATADSSAFG----------PGSPHPPAAHPPGATAFPFAHSP-------------SGPGSGGSAGGRDGSAYQGALLPRE-QFAAP-LGRPVGTSYSATY---------------------------PAYVSPDVAQSWTAGPFDGS------------------------------VLH-------GLPGRRPTFVSDFLEEFPGEGRECVNCGALSTP-LWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLS--------------------------SSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKP--SLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEP-------EDFAFPSTAPSPQAGLRG--ALRQEAWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61169-1", "uniprot_id": "GATA6_MOUSE", "id": "Q61169-1", "name": "Transcription factor GATA-6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDAEAVAGPPGRSLLLSPYASHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSS-----------QGP--AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLSGLPY-LQGAGSGPSNHAGGAGAHPGWSQA-SADSPPYG-GGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGTGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHP---------------------TYSPYMAAPLTPAWPAGPFETP------------------------------VLHSLQGRAGAPLPVPRGPSTDLLEDLS-ESRECVNCGSIQTP-LWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSGSVPMTPTSSSS-NSDDCTKNTS--PSTQATTSGVGASVMSAVGENANPENSDLKYSGQ--------DGLYIG-VSLSSPAEVTS--SVRQDSWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46153-1", "uniprot_id": "GATA6_RAT", "id": "P46153-1", "name": "Transcription factor GATA-6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDTEAVAGPPGRSLLLSPYTSHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSS-----------QGP--AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPY-LQGAGSGPSNHAGGAGAHPGWPQA-SADSPPYG-GGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGAGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHP---------------------TYSPYMGAPLTPAWPAGPFETP------------------------------VLHSLQSRAGAPLPVPRGPSADLLEDLS-ESRECVNCGSIQTP-LWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSS--VPMTPTSSSS-NSDDCTKNTS--PPTQSTASGVGASVMSAVGESANPENSDLKYSGQ--------DGLYIG-VSLSSPAEVTS--SVRQDSWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92908-1", "uniprot_id": "GATA6_HUMAN", "id": "Q92908-1", "name": "Transcription factor GATA-6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTDGGWCLPKRFGAAGADASDSRAFPAREPSTPPSPISSSSSSCSRGGERGPGGASNCGTPQLDTEAAAGPPARSLLLSSYASHPFGAPHGPSAPGVAGPGGNLSSWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAPEQPEEMYQTLAALSS-----------QGP--AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYHLQGSGSGPANHAGGAGAHPGWPQA-SADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARFPYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHP-----------------SPYSPYVGAPLTPAWPAGPFETP------------------------------VLHSLQSRAGAPLPVPRGPSADLLEDLS-ESRECVNCGSIQTP-LWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSS-NSDDCSKNTS--PTTQPTASGAGAPVMTGAGESTNPENSELKYSGQ--------DGLYIG-VSLASPAEVTS--SVRPDSWCALALA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08369-1", "uniprot_id": "GATA4_MOUSE", "id": "Q08369-1", "name": "Transcription factor GATA-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAAN-----------HGPPPGAYEAGGPGAFMHSAG-------AASSPVYVPTPRVPSSVLGLSY-LQGGGSAAAAGTTSGGSSGAGPSG-AGPGTQQG----SPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYGSGGGAAGAGLAGRE-QYGRPGFAGSYSSPYPAYMADVG-----------------------ASWAAA---AAASAGPFDSP------------------------------VLHSLPGRANPG----RHPNLDMFDDFS-EGRECVNCGAMSTP-LWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPAG-ETLPPSSGASSGNSSNATSSSSSSEEMRPIKTEPGLSSHYGHSSSMSQTFST--VSGHGPSIHPVLSALKLSPQGYASPVTQTSQASSKQDSWNSLVLADSHGDIITA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46152-1", "uniprot_id": "GATA4_RAT", "id": "P46152-1", "name": "Transcription factor GATA-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAAN-----------HGPPPGAYEAGGPGAFMHSAG-------AASSPVYVPTPRVPSSVLGLSY-LQGGGSGAASGATSGGSSGAGPSG-AGPGTQQG----SPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYSSSGGAAGAGLAGRE-QYGRPGFAGSYSSPYPAYMADVG-----------------------ASWAAA---AAASAGPFDSP------------------------------VLHSLPGRANPA----RHPNLDMFDDFS-EGRECVNCGAMSTP-LWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPPG-ESLPPSSGASS-NSSNATSSSSSSEEMRPIKTEPGLSSHYGHSSSMSQTFST--VSGHGSSIHPVLSALKLSPQGYPSPVTQTSQASSKQDSWNSLVLADSHGDIITA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43694-1", "uniprot_id": "GATA4_HUMAN", "id": "P43694-1", "name": "Transcription factor GATA-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAAN-----------HGPPPGAYEAGGPGAFMHGAG-------AASSPVYVPTPRVPSSVLGLSY-LQGGGAGSASGGASGGSSGGAASG-AGPGTQQG----SPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYSSGGGAAGAGLAGRE-QYGRAGFAGSYSSPYPAYMADVG-----------------------ASWAAA---AAASAGPFDSP------------------------------VLHSLPGRANPAA---RHPNLDMFDDFS-EGRECVNCGAMSTP-LWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASS-NSSNATTSSS--EEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23772-1", "uniprot_id": "GATA3_MOUSE", "id": "P23772-1", "name": "Trans-acting T-cell-specific transcription factor GATA-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVTADQPRWVSHHHP--------AVLNGQHPDTHHPGLGHSYMEA-QYPLT-EEVDVLFNIDGQGNHVPSYYGNS--VRATVQRYPPTH--HGSQVCRPPLLHG-SLPWLDGGK-ALSSHH---TASPWNLSPFSKTSIHHGSPGPL----------------SVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGS-------ARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTE----GRECVNCGATSTP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKV------------HDALEDFPK----------SSSF-NPAALSRHMSSLSHISPFSHSSHMLTTP-------TPMHPPSGLSFGPHHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23771-1", "uniprot_id": "GATA3_HUMAN", "id": "P23771-1", "name": "Trans-acting T-cell-specific transcription factor GATA-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVTADQPRWVSHHHP--------AVLNGQHPDTHHPGLSHSYMDAAQYPLP-EEVDVLFNIDGQGNHVPPYYGNS--VRATVQRYPPTH--HGSQVCRPPLLHG-SLPWLDGGK-ALGSHH---TASPWNLSPFSKTSIHHGSPGPL----------------SVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGS-------ARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSST-----GRECVNCGATSTP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKV------------HDSLEDFPK----------NSSF-NPAALSRHMSSLSHISPFSHSSHMLTTP-------TPMHPPSSLSFGPHHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91428-1", "uniprot_id": "GATA3_DANRE", "id": "Q91428-1", "name": "Transcription factor GATA-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVSPEQHRWVTHHT------------VGQHPETHHPGLGHSYMDPSQYQLA-EDVDVLFNIDGQSNHP--YYGNP--VRA-VQRYPPPP--HSSQMCRPSLLHG-SLPWLDGGK-SIGPHH---STSPWNLGPFPKTSLHHSSPGPL----------------SVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSS-------VRQEDKECIKYQVSLAESMKLDSAHSR-SMASIGAGASSAHHPIATYPSYVP----DYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSE----GRECVNCGATSTP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKS------------HDSMEDFSKSL-----MEKNSSF-SPAALSRHMTSFP---PFSHSGHMLTTP-------TPMHPSSSLPFASHHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O09100-1", "uniprot_id": "GATA2_MOUSE", "id": "O09100-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGK-AALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKG------------AECFEELSKCM-----QEKSPPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924Y4-1", "uniprot_id": "GATA2_RAT", "id": "Q924Y4-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGK-AALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASPSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLAPMGTQPATHHPIPTYPSYVPASAHEYGSGLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKG------------AECFEELSKCM-----QEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23769-1", "uniprot_id": "GATA2_HUMAN", "id": "P23769-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPGLAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGK-AALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSE----GRECVNCGATATP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKG------------AECFEELSKCM-----QEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXB8-1", "uniprot_id": "A0A8M3AXB8_DANRE", "id": "A0A8M3AXB8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAADQSRWMAHHH---------AVLNGQHPESHHHGLTHNYMEPMAPLLPPDEVDVFLNHLDSQGNP--YYSN---SRARVSYGQAHARLTGSQVCRPHLIHSPGIPWLDSGK-AALSAA---HHNAWAVSHFSKPGLHPASAAYP------------CSSSSSTAPVSSLTSATHSSPHPLYNFPPTPPKDVSPDP---GPSSPTS-----TTARMDEKESIKYQVSIADGMKMEGCSPLRGSLAMSAQTPSTHHPIPTYPTYSLPAPHDYGGGLFHPGTLLSGSASSFTPKCKSKTRSCSEFCTEGRECVNCGATSTP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------------------SAARRAGTCCANCQTTTTTLWRRNGNGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKRSKRS------------GEGFEELSKCM-----QDKTSPFGSASALASHMPHMGHLPPFSHSGHMLPTP-------TPIHP----TFSHPHHSGRSPAWAEPH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91623-1", "uniprot_id": "GATAC_DROME", "id": "P91623-1", "name": "GATA-binding factor C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMTSTAEAAARSWYDSPRLGGGGSSGGGNGGGVSPQTNGLGSAGSSLAHSHHSLS-SGASSAGSSVGVGSALGGGGGSGLDTSDMSAFYALESNGHHRRYYPSYHQHTSRMPSTHASP-QVCRPHFHTPLSPWLTSEHKSFAPASAWSMGQFACPQ-------EPQVEHKLGQMGQSHQTTAAGQHSFPFPPTPPKDSTPDSVQTGPS--------------------EYQAVMNAFMHQQATGSTSLTDASCALDIKPS---------------------IQNGSASGSSGSGTTHTSTPKQREEGR------ECVNCGATSTP-LWRRDGTGHYLCNACGLYYKMNGQNRPLIKPKRRLT--------------------LQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKKKKGL------------GGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGHLSSGLHPAHAHMHGSWYTGGMGALGASSGLQGGFSTAGSLSGAVVPHSQPYHLGLSSMGTWRTDYT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QAH1-1", "uniprot_id": "A0A8M9QAH1_DANRE", "id": "A0A8M9QAH1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSVQKGFLTDMES-----------SVDQVRWGSSEVMPTYTSDSSFLLHGEEASIFPCTDADHSGLPSLFSSPVHSRPTAAFQHSPVYPIYSSPFLG------NLSWLEGSSGSSLTNYFPSSPSSWHSSAFSKASSSSFSSSSAR----------------PEQKESVKGERSSPPGGGLFPLNSSLSG--------------------------------VYPHSHSTKTHYSPYGGHTQDYSSS----------------------------------LLYAPATFTPKLCSKMNFSPLD---ARECVNCGATATP-LWRRDGTGHYLCNACGLYHKMNGQNRPLIRPKKRP--------------------------VVSKRIGTQCANCQTSTTTLWRRNSSGEPVCNACGLYFKLHNVNRPLAMKKEGIQTRNRKVSSKNRKGKKF------------STMEENLYCDFP--------KTPACDQHFDMYSQSPAALGVYSHSGQSTAYLP----------------YPYHSSPAVLPSTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17679-1", "uniprot_id": "GATA1_MOUSE", "id": "P17679-1", "name": "Erythroid transcription factor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPGLGALGTSEPLP----------QFVDSALVSSPSDSTGFFSSGPEGLDAASSSTSPNAATAAASALAYYREAEAYRHSPVFQVYPL-----------------LNSMEGIP----------GGSPYASWAYGKTALYPASTVCP-----------------SHEDAPSQALEDQEGKSNNTFLDTLKTERLSPDLLTLG-------------------------TALPASLPVTGSAYGGADFPSP---------------------------FFSPTGSPLSSAAYSSPKFHGSLPLAPC---EARECVNCGATATP-LWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRM--------------------------IVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYFKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSNLAG-------AGAAEGPAGGFMVVAGSSSSGNCGEVASGLALGTAGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTTSFPTGPAPTTSSTSVIAPLSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43429-1", "uniprot_id": "GATA1_RAT", "id": "P43429-1", "name": "Erythroid transcription factor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPGLGALGTSEPLP----------QFVDSALVSSTSDSAGFFSSGPESLDTASSSTSPNAATAAATALAYYREAEAYRHSPVFQVYPL-----------------LNSMEGIP----------GSSPYASWAYSKTALYPASTVCP-----------------SHEDAPSQTLEDPDGKNNNTFLETLKTERLSPDLLTLG-------------------------TALPTSLPVTSSAYGGADFPSP---------------------------FFSPTGSPLSSAAYSSPKFHGSLPLAPC---EARECVNCGATATP-LWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRM--------------------------IVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLAG-------AGAAEGPAGGFMVVAGGSSSGNCGEVAPGLTLGTAGTAHLYQGLGPVVLSGPVSHLMSFPGPLLGSPTASFPTGPVPTTTSTSVVSPLSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15976-1", "uniprot_id": "GATA1_HUMAN", "id": "P15976-1", "name": "Erythroid transcription factor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFPGLGSLGTSEPLP----------QFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPL-----------------LNCMEGIP----------GGSPYAGWAYGKTGLYPASTVCP-----------------TREDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLG-------------------------PALPSSLPVPNSAYGGPDFSST---------------------------FFSPTGSPLNSAAYSSPKLRGTLPLPPC---EARECVNCGATATP-LWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRL--------------------------IVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGG-------TGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52168-1", "uniprot_id": "PNR_DROME", "id": "P52168-1", "name": "GATA-binding factor A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGILLSDGDS-----------------TSDQQSTRDYPHFSGDYQNVTLSAASASTSASASATHVAAVKMYHSSAVAAYTDLAAAGSAASAGVGVG------------------------VSGYHQQAVNAPVYVPSNRQYN-------------------HVAAHFGSAAAQNAWTTEGFGSAHAQFYSPNAAVMMG------------------------------------------------------------------------------SWRSAYDPSGFQRSSPYESAMDFQFGEGRECVNCGAISTP-LWRRDGTGHYLCNACGLYHKMNGMNRPLIKPSKRLVS-----------------------ATATRRMGLCCTNCGTRTTTLWRRNNDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTLEAIKECKEEHDLKPSLSLERHSLSKLHTDMKSGTSSSSTLMGHHSAQQQQQQQQQQQQQQQQQQQQSAHQQCFPLYGQTTTQQQHQQHGHSMTSSSGQAHLSARHLHGAAGTQLYTPGSSSGGGSASAYTSHSAETPALSNGTPSPHYQHHHHLGGTHGHHVTAAAAHHHFHAAAAVAAYGVKTEASATNYDYVNNCYFGGTFGALGGAATTTAMAGGAASELAGYHHQHNVIQAAKLMATS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52172-1", "uniprot_id": "SRP_DROME", "id": "P52172-1", "name": "Box A-binding factor", "aln": "MTKTTKPKEKAAAGGAVIGSGSGLGSVTKAGGGSLLSNAADSKIRTAKSNNNKRQAGRAATALAATTTASALAATTTAGATGSNAAANETEIAIETENGEAATPTAAATAAAANLSSLESARSQALTSVVSETARQAVTTANASATSTSTVTAATEIATATASDTAATSEAAIDDDPSAINTNNNNNNSKAQNDASESVKTKVISYHQSEDQQQQQQQQAQIYEQQQQFLSQQLISHHQQEQHQQAQQQQHQQVVQEQHQASWLAYDLTSGSAAAAAAAAAAASHPHLFGQFSYPPSHHTPTQLYEHYPSTDPIMRNNFAFYSVYTGGGGGVGVGMTSHEHLAAAAAAAAAVAQGTTPNIDEVIQDTLKDECFEDGHSTDYHVLTSVSDMHTLKDSSPYALTHEQLHQQQHHHQQQLHHHQQQQQQLYHQQQQQQ-------QQQQHHHHHNNSTSSAGGDSPSSSHALSTLQSFTQLTSATQRDSLSPENDAYFAAAQLGSSLQNSSVYAGSLLTQTANGIQYGMQSPNQTQAHLQQQHHQQQQQQHQQHQQQQLQQQQQQHHHNQHQHHNSSSSSPGPAGLHHSSSSAATAAAVAAATAAVNGHNSSLEDGYGSPRSSHSGGGGGGTLPAFQRIAYPNSGSVERYAPITNYRGQNDTWFDPLSYATSSSGQAQLGVGVGAGVVSN-VIRNGRAISAANAAAAAAADGTTGRVDPGTFLSASASLSAMAAESGGDFYKPNSFNVGGGGRSKANTSGAASSYSCPGSNATSAATSAVASG-TAATAATTLDEHVSRANSRRLSASKRAGLSCSNCHTTHTSLWRRNPAGEPVCNACGLYYKLHSVPRPLTMKKDTIQKRKRKPKGTKSEKSKSKSKNALNAIMESGSLVTNCHNVGVVLDSSQMDVNDDMKPQLDLKPYNSYSSQPQQQLPQYQQQQQLLMADQHSSAASSPHSMGSTSLSPSAMSHQHQTHPHQQQQQQLCSGLDMSPNSNYQMSPLNMQQHQQQQSCSMQHSPSTPTSIFNTPSPTHQLHNNNNNNNNSSIFNNNNNNNSSSNENNNKLIQKYLQAQQLSSSSNSGSTSDHQLLAQLLPNSITAAAAAAAAAAAAAIKTEALSLTSQANCSTASAGLMVTSTPTTASSTLSSLSHSNIISLQNPYHQAGMTLCKPTRPSPPYYLTPEEDEQPALIKMEEMDQSQQQQQQQQHQQQQHGEIMLSRSASLDEHYELAAFQRHQQQQQQLQQQTAALLGQHEQHVTNYAMHKFGVDRETVVKME", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VF00-1", "uniprot_id": "Q9VF00_DROME", "id": "Q9VF00-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVCKTISPSVNMQLKMEQQTTQQQQQQQQQQQQQQQLQQQQHQALTKQQLQLLDKIKLESSNGADQLAQQTANNLDEQQEQQQQHQQQAATSVGVVVQTGQAGVSEPEEQYVVVPRNQRRILTTAGTLELNEAREGEPSTNASNASSGSASDSHIEYQRSAHQSPGATHYVQMAPRNAEVTEQVGAAAGAPPGTIFAYPIICNGDDVAAIKIETLEKGEATGESQ-------QQQQQLQQHQHQQQQQCPTPNGASYGETIVISSEAEALQHHHQQQQQHQQQQHQQQHHQHQAAAAASAAAQTVHIATSSHGGTVRFVTEDVRFTTAGPETSASNMYYDVPVVDGSVHANESKTYADLG-----NAYAPFPPSSSFSSNSYAATLQQGNTIYSVPGTGQFLAKSESGLNQTGLLRQTG-----------------PATFQTISFEGGNGIEPLWASPAPPEYQSVQFSNFHP-------QVIDEYGSGNMSTSHWPPASSIGQYDGSLVTASSTSSPNHELKCENCHGP--FLRKGSEYFCPNCPAFMRMAPRITQRQAKPKAAAAP-------------------------NNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMKKEGIQKRKRKPKNNGGAPMHRAPLP---------SMSQGVNLMANSPLYPSQVPVSMLNSQLNSQQNSSPELHDMSTTGQAGGQRVVSISLNATAPPTPDGTLNMSARHHVTGESHSPYSQQSTPQSQSPHLPGTVPINRQIVQPVPTIESSRSSNTELTPSVITRTGLPERSSNN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKZ0-1", "uniprot_id": "Q9VKZ0_DROME", "id": "Q9VKZ0-1", "name": "", "aln": "--------------------------------------------------------------------MNNVPHKFRQVCRLCLTLVNECDVAVLQIYDNSSHNNSAPDRISADFRGVANRANCFCSALSPNPCSCIVDNPLSANKNERRNQGTPVPVPIPIPVSVPVPVPSQQIQSQTLHHHQNQTKIHYTPSVPSAADAKSSERERQCQLESDIAERSTVFKSQSSSDHEHIEYSGETPSPSASLSQSQTKSEPMREEEEHQHNHNQQSGREETSVNTTNISGTDNYGKEHGRDDSSSPHLTFQIFNCLSIKALPNDGLPNVVCGDCRQKLDSFEKFRTMAHNSQIALKEFLNISKNLRPDPNDLETKLDAILKASSEAIAAKALTELSTFSKVKYDHSKLDSSIQPGLDRKIEISNQEMPAHSLYPSLFKS-------ITMKSDQKSKAMSGSSHSQFDSKLQKDSDIEKYENLQQQLETAAVLMDISKKIVISPPCSNPQSPCFSAAVDTSIKSSVIKSKRPSNQNEIQDGVEIDLSVKKQKNDYSNQRNAAPIHHFCQTPMLDIQSHLRSEEDFQNYSITINQVGGSDFKSKAPKASTGSLLDSGDSSDSHKLEMDITSSIN----------------DRKTPDSLSSDHATDAATTQLWQALARSAAKSKEDNPASQIFRN---------MMSQPFAFPVPSTVSFTKVPEEPIALLKDLSEAQSSKSKPCRRKQSFPTKTDCIDVVNENVTDTYTTSEATPDDKKDKRNIN--------------------LFNAIPGAQKDMSCSNCGTLTTTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRPKELERSKKKHKQMS--------SCSSIETTKQDFLTARESLAISGLVLNKFKKEIDDTETPAAAALKDILSRRKK------SNSLPAFNDTCESADLSAPLNLVSSENNAKLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43574-1", "uniprot_id": "GAT1_YEAST", "id": "P43574-1", "name": "Transcriptional regulatory protein GAT1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHVFFPLLFRPSPVLFIACAYIYID---------IYIHCTRCTVVNITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPDSNRILNLSWRLHNRTSFHRINRIMQHSNSIMDFSASPFASGVN------AAGPGNNDLDDTDTDNQQFFLSDMNLN------------GSSVFENVFDDDDDDDDVETHSIVHSDLLNDMDSASQRASHNASG-----------------------FPNFLDTSCSSSFDDHFIFTNN--------------------------LPFLNNNSINNNHSHNSSHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSIVKPGSRRNSSVRKKKPALKKIKSSTSVQS----------------SATPPSNTSSNPDIKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSS------LNPGAAGKKKNYTASVAASKRKNSLNIVAPLKSQDIPIPKIASPSIPQYLRSNTRHHLSSSVPIEAETFSSFRPDMNMTMNMNLHNASTSSFNNEAFWKPLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *:** * *.:**:. * :******: *** : ** ::: : *:.*.* . ", "identical_positions": 22, "similar_positions": 19, "identity": "1.73%" }, { "cls_id": "homologset.agr.SGD:S000001876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6R2-1", "uniprot_id": "DLDH_RAT", "id": "Q6P6R2-1", "name": "Dihydrolipoyl dehydrogenase, mitochondrial", "aln": "MQSWSRVYCSLAKKGHFNRLSHGLQGASSVPLRTYSDQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHLAHGKDFASRGIEIP-EVRLNLEKMMEQKRSAVKALTGGIAHLFKQNKVVHVNGFGKITGKNQVTATTADGST------QVIGTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKLVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSD-GKIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPKGRIPVNTRFQTKIPNIFAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGVEFKVGKFPFAANSRAKTNADTDGMVKILGHKSTDRILGAHILGPGAGEMVNEAALALEYGASCEDVARVCHAHPTLSEAFREANLAASFGKPINF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08749-1", "uniprot_id": "DLDH_MOUSE", "id": "O08749-1", "name": "Dihydrolipoyl dehydrogenase, mitochondrial", "aln": "MQSWSRVYRSLAKKGHFNRISHGLQGVSSVPLRTYADQPIEADVTVIGSGPGGYVAAIKSAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEIP-EVRLNLEKMMEQKHSAVKALTGGIAHLFKQNKVVHVNGFGKITGKNQVTATKADGST------QVIDTKNILVATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKLVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQRQGFKFKLNTKVTGATKKSD-GKIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPKGRIPVNNRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEFKIGKFPFAANSRAKTNADTDGMVKILGHKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAAAFGKPINF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09622-1", "uniprot_id": "DLDH_HUMAN", "id": "P09622-1", "name": "Dihydrolipoyl dehydrogenase, mitochondrial", "aln": "MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMS-EVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGT------QVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSD-GKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09624-1", "uniprot_id": "DLDH_YEAST", "id": "P09624-1", "name": "Dihydrolipoyl dehydrogenase, mitochondrial", "aln": "---MLRIRSLLNNKRAFS---------STVRTLTINKS---HDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQMH-TEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIG-ASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAA-YDKAIHC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * :: *. *:* * .. **.:**.**.*******:*****:*.*:**. .********************* :* * .: .***:: ::::*: :: : * *** ***** ***:***.: :* *.: .:.:: .* .** :::..***::************ ***:.***********::*:::.:**.*:**:*:***:.***:.**.*** ::* .:* *::* *::*::**:.***.*** .*.::.* . ::: :* :. .* * : .:****.:****: .** *::*:*:* :**: :: :*::*:*:* .:***. *********:*** .** : * *::** :***:*:*********:****** *:::*:************** **:*:**** ...*:*:*****:**.****: **.********.**:**************:***:** :.*.*: ", "identical_positions": 270, "similar_positions": 150, "identity": "52.22%" }, { "cls_id": "homologset.agr.SGD:S000001877", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96EK6-1", "uniprot_id": "GNA1_HUMAN", "id": "Q96EK6-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTATFSPAISPTHPGE-GLVLRPLCTADLNRGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKR------------GRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKK--FGYTVSE---ENYMCRRFLK------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JK38-1", "uniprot_id": "GNA1_MOUSE", "id": "Q9JK38-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPTHPGE-GLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKR------------GRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKK--FDYTVSE---ENYMCRRFLK------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y6Y7-1", "uniprot_id": "A0A8I5Y6Y7_RAT", "id": "A0A8I5Y6Y7-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MVPDETPMFDPSLLKEVDWSHNTTILSLATSPTHPGG-SLVLRPLCTVDLNKGFLKGIGSVERDWRHQPGVVREIFEPMKRSGDYYVTVVEDGTLGQIVATATLIIEHKFIHSCAKR------------GRVEDAVISDACRGKQLGKLLP-TLTLLS-KMSCYNITLECLPQHVGFFKKK-FAYTVSE---ENYMCWKFLK------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AKF3-1", "uniprot_id": "A0A8I6AKF3_RAT", "id": "A0A8I6AKF3-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGE-GLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKSSFLLLQPVSSLTTRLKNAVVCQCSATRGCLWLLGVQMIRKGGDFLTKGIYFQLESFLALYFSTVCLPFLVVKSMGSKQLCHLLSAAHF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VAI0-1", "uniprot_id": "GNA1_DROME", "id": "Q9VAI0-1", "name": "Probable glucosamine 6-phosphate N-acetyltransferase", "aln": "MVQLTEETYLYDPNLLLKLDFHRSPANFKPFISAANPGEPWMKVRPLKDTDYDRGFLQLLSQLTHVGNVNRTQFLTRFSQMKASGDYFVTVIEDTRKNEIIGAASLVIERKFIHNCAVR------------GRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYES--LGYVAIPG-NSNSMTIRYDEGPTLKRNATSAGSSGTVGDSCQTVSLDFAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43577-1", "uniprot_id": "GNA1_YEAST", "id": "P43577-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "-MSLPDG---FYIRRMEEGDLEQVTETLKVLTTVGTITP--------------ESFSKLIKYWNEATVWND-------NEDKKIMQYNPMVIVDKRTETVAATGNIIIERKIIHELGLC------------GHIEDIAVNSKYQGQGLGKLLIDQLVTIGFDYGCYKIILDCDEKNVKFYEK--CGFSNAG------VEMQIRK------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : * : . :. : ..* : : . . . * :* *: * : .:..::**:*:**. . :::: .: . : *: : . . : :: ::.. : : ", "identical_positions": 12, "similar_positions": 51, "identity": "5.13%" }, { "cls_id": "homologset.agr.SGD:S000001878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K5E4-1", "uniprot_id": "A0A0G2K5E4_RAT", "id": "A0A0G2K5E4-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSPRWFRVAVGTPRLPAAAGRGVQQPQGGVVAASLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTASFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCSGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTVPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSTGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M87-1", "uniprot_id": "DNJA3_MOUSE", "id": "Q99M87-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAAWCSPRWLRVAVGTPRLPAAAGRGVQQPQGGVVATSLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTTSFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGTSS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTIPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSAGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EY1-1", "uniprot_id": "DNJA3_HUMAN", "id": "Q96EY1-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLSVPAFASSLTSCGPRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASG--SQHSY------WKGGP---TVDPEELFRKIFG--EFSSSSFGDFQT----VFDQPQEYFMELTFNQAAKG-VNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISP--CVVCRGAGQAK-QKKRVMIPVPAGVEDGQTVRMP-------------------VGKREIFITFRVQKSPVFRRD-GADIHSDLFISIAQALLGGTARAQGLY-ETINVTIPPGTQTDQKIRMGGKGIPRINSYGYGDHYIHIKIRVP--KRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSG------GSTMDSSAGSKARR---EAGE-------------------DEE--------------------GFLSKLKKMFTS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27237-1", "uniprot_id": "DJTID_DROME", "id": "Q27237-1", "name": "DnaJ homolog l(2)tid, mitochondrial", "aln": "MMISCKK--LFVFR---QLPAVR-----------------RCLAAAAFST------PRATSYRILSSAGSGSTRADAPQVRRLHTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQS---WQFRS---SIDPEELFRKIFGEGNFRTNSFDDFADSK-FGFGQAQEMVMDLTFAQAARG-VNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYP--CSECEGKGRTV-QRRKVTVPVPAGIENGQTVRMQ-------------------VGSKELFVTFRVERSDYFRRE-GADVHTDAAISLAQAVLGGTVRVQGVY-EDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEKSEGKDQWTDNEKTKAKEGGGSGSGQGDGGGGGFISKIKSMFN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35191-1", "uniprot_id": "MDJ1_YEAST", "id": "P35191-1", "name": "DnaJ homolog 1, mitochondrial", "aln": "--MAFQQGVLSRCSGVFRHHVGHSR------------------------------HINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKE-PDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIR-GDMKVQYKIVVK--KPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAG------TAINEEILKKQKQEEEKHAKK-------------------DDD--------------------NTLKRLENFITNTFRKIKGDKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : : .* * **: :.*. :******:******** **: *.* .** :: :***:**** **::** :* .* * .. . . . . :: *:** ** :. . .:. * . .::* :*. * * :. .. :* * * *. :*.*: * * *:* . * * * *** * * * *.* * : : : : :* *:::*:.**: :. :::: :**::. * . *: * *.:: * ****. : : :.: .* . .: * : . *: : .: ** :: ** * * . * : *: * . . * : : * . *:: . :.:::.::. ", "identical_positions": 102, "similar_positions": 122, "identity": "17.23%" }, { "cls_id": "homologset.agr.SGD:S000001883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSSPAIPSLRRT-------APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLALLR-RPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS----------------------------------------------------------------------LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSSPAIPSLRRT-------APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLAMLR-RPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS----------------------------------------------------------------------GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTSPVIPALKRS-------SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ---SSRVSWAEAW-EPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTL--------------------------------------------------------------------TPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRG------EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN---KVN-VWAALN-RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTG--IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ---------------------------------------------------------------------------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGISNSTSNEND------------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVS-------WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV---DAS-VKDLFS-NRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST---LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR----------------------------------------------------------------------------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDR-------TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ---ATQNTCLELF-KRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA----------------------------------------------------------------------------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDR-------NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ---ASRNTMLELL-KLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT----------------------------------------------------------------------------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6NWF1-1", "uniprot_id": "GTR12_DANRE", "id": "Q6NWF1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAPEESIRMTSDPQSKIYVQNPDTHIHLEQGPSAKSGNGRA--------------------------------------------------------------------------------------------------------------------------------------------------LVLCSVSVACLSGLLMGYEMSLISGALLQLRDV-----------LTLSCPEQEQVVGSLLLGAFLLSLGGGTILDHYGRRFTIILTALLCVLGTLLSVCVVS-FWALVVGRMLVGMSVALSGTASCLYAAEVAPAAWRGRCVCVYELMVVLGMLLGFGLSWAFAGVP--DGWRFTFGGALLPALLQAGVMPLLPDSPRFLLAQQREKEAHATLLRLRAGIKEVEPVEDELRAIRLAMGAE---RLHGFLDLFQSRDNMLQRLLVGAALVFLQQATGQPNILAYASTVLSSVGFHGNEAATLASTGFGVVKVGGTIPAIFLVDKVGPKALLCVGVVVMMLSTATLGAITMQSRTHVSSLCRGPGNTANFTLFETGDETDIQTNTPLGLYQPQNKLKTNTFLTSINDTREHWILNHTYNHRTALMETAELSKKDSAKIALQSLHEVSPSLKWISLVSLLVYVAGFSISLGPMVHVVLSAIFPTGIRGKAVSVISAFNWATNLLISMTFLTLTERIGLPTVIFSYSAMSFLLVVFVIVFVPETKGRSLEQISKELAMKNHLRGTLLCHRRKHKATAQPSQEEKALATV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43581-1", "uniprot_id": "HXT10_YEAST", "id": "P43581-1", "name": "Hexose transporter HXT10", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSSVSILGTSAKASTSLSRKDEIKLTPETREASLDIPYKP-------------------------------------------------------------------------------------------------------------------------------------------IIAYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQ---DSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQ-----------------------------------------------------------------------------------GKDQPSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFMGCLIFS-YFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : . . . :. : : : **: : : . . .*:: *: . .* ** : * : : . : :*::* ::: . ..* :: . : : : :** * .: : :: : .* :.. . . :: * : * . * . :. : : .:: ::: .*: :::. :. * .: .* :: . :. : **:* : .:: . ", "identical_positions": 25, "similar_positions": 93, "identity": "2.55%" }, { "cls_id": "homologset.agr.SGD:S000001885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z902-1", "uniprot_id": "FBXW7_RAT", "id": "D3Z902-1", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNASS---SQVDEEQMNRVVEEDPQQQPRHQEEEHTARNGELVGADPRP-GAQNDSQQG--QVEENNNRFVS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQEEEEEE--EEEEEEEEEMDQESDDFDQSDDSSREDEHT------------------------------------------------HNSNVTNCTSVVDLPINQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSDYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KIIKPG---FIHSPWKSAYIRQHRIDTNWRRGELRSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBV4-2", "uniprot_id": "FBXW7_MOUSE", "id": "Q8VBV4-2", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNASS---SQVDEGQMNRVVEEDPQQQARHQEEEHTARNGELVGANPRP-GDQNDTQQG--QVEENNNRFIS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQEEEEEE--EEEEEE---MDQESDDFDPSDDSSREDEHT------------------------------------------------HNSNVTNCSSVSDLPAHQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSDYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KIIKPG---FIHSPWKSAYIRQHRIDTNWRRGELKSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969H0-1", "uniprot_id": "FBXW7_HUMAN", "id": "Q969H0-1", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNPSS---SQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRP-GGQNDSQQG--QLEENNNRFIS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQDEEDEE--EEE------MDQESDDFDQSDDSSREDEHT------------------------------------------------HTNSVTNSSSIVDLPVHQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSEYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KVIKPG---FIHSPWKSAYIRQHRIDTNWRRGELKSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PIU0-1", "uniprot_id": "A0A8M9PIU0_DANRE", "id": "A0A8M9PIU0-1", "name": "F-box/WD repeat-containing protein 7", "aln": "MSRSMCGCGCSFISSLMKRLGRSACCSD-----------------------------------LLSCSHTSEHLQRLATGCPSQH---------------KNAKSLSSSDSLAKVQEVASWLLEMNQDLLSGGSGSR--AAQQQRPRPGTAGAGNSISGRTPQPQPEHPDQVLEEPEQEEAQQQRREPAEEEDEGGPERQQD-GDEQPWPSGGEPMEDGEGRRSE---VNGDE--------KGAQWLWEQEQRRRRRPHREEEEENEEEEEN-------------------------------------------NNSGREGQVGAGLRSEEDDDRPEEDNEGEEEMDQDSDEFEHSEESEREEEEEDGEEE-------------------------------------EGEEGLHSPSLRTSVSDHNDNTDQSSGRQRQSLRSP----NRMKRKLDHGP-----------------------------------------------------------------------EVRSFTTGKKPCP-----SPTG----QQYPA---------------------------------------------------TFGDLRAVNGQV--------------------------------------------------------------------------------------------------------------------------PQRRR-----------------------------------------------------------------ITSIQP------------------PTGLQEWLRTFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPRELALHVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWKEKCKEEGIDEPLHIKRR--KVIKPG---FTHSPWKSAYIRQHRIDTNWRRGDLKSPKVVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZF4-1", "uniprot_id": "FBXW7_DROME", "id": "Q9VZF4-1", "name": "F-box/WD repeat-containing protein 7", "aln": "MERGCPAASSESVTSAGERTQSAVTSSTSTWVKSQASTSRKTEASEESGLGAVDAEVGAGREAFVSMSTLREDVEDVCVSSNSQHGFAVVLDDESSTFEISSSNSLPTSAGAASTVGVVAVDDSSSTDTLNGGHPDLGHPASSEHSRQGFFNEDNEDPPVVCLINDDDDDEEPEPEEDDEEELIEDEDEDAVDIVTGAISCPNTSQLALADGTIMAADGSKIFLETPVVEEAQPHPGQVVTTGSQSELTGKPKRLSDEFLLGEEDQAENLALGRCIKSEPVNPVDDNPSEGDDGATCFSLHDRLMSVRLKQMSLTANTVSNPSPAASANAAAPEEASTSNSSSTSSSALSRADIESMDLIERRDFETEQRLTGGIILRTSSMVSQNKLNLSLIKSMAGGSKAANGSGTANSDDWPSSSNGRTVSSDSKYTYKDLSTTPTSSRKYTNSRLSKSTAKLNLGSSLGASSCSQHRSGSSSTSKSMESSTSCTGAARTDVYTNTNSNDYPSLAPTTSGSSTSGGSCQQDQEENVSASVSYSSVGSQTSQESGCSRTTAINPTAACSTGSACLGDSQASTSASTSSGAGASNRCQYATTSTTKAARQVNASAQTQERFLTRSNPPAASGAGSVGANPTASVRQRRNGSSDVVHLEVVVEEGAGGGDGGVVEPGDFSAEEPWANCDEENNCSDLEEICTCQNGNGSSYGGSNASLSETFDMDAMDPDEPISLSLSSASAGFTEYSLTNPSSLMSHQRKRKFNEGRLLDGGDYSVTISSSGEVGGPGSGVSDNCRKRIAYDFASTPRSSQHLGPTAVLSVTPSSHLTSSTPGSALGRRTPRSVPSRDNPPPELQHWLAQFQRWSHVERLLALDRLIDHCDPSQVRHMMKVIEPQFQRDFISLLPRELALFVLSYLEPKDLLRAAQTCRSW-RFLCDDNLLWKEKCRKAQILAEPRSDRP--KRGRDGNMPPIASPWKAAYMRQHIIEMNWRSRPVRKPK-VLKGHDDHVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGN-IIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSK----VVSGSRDATLRVWDIEQGS-----------------------CLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDG--LHVVSGSLDTSIRVWDVETGN--------------------CKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWR------------------IRANDTKLICAVGSRNGTEETKLMVLDFDVEGACVKCS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07834-1", "uniprot_id": "CDC4_YEAST", "id": "P07834-1", "name": "Cell division control protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------MGSFPLAEFPLRDIPVPYS----------YRVSGGIASSGSVTALVTAAGTHRNSSTAKTVETEDGEEDIDEYQRKRAAGSGESTPERSDFKR------VKHDNHKTLHP---VNLQN--------TG--------------------------------------------------------------------------------AASVDNDGLHNLTDISNDAEKLLMSVDDGSAAPSTLSVNMGVAS------------------------------------------------HNVAAPTTVNAATITGSDVSN-----NVNS----ATINNPMEEGA------------------------------------------------------------------------LPLSPTASSPGTTTPLAKTTKTINNNNNIA------------------------------------------------------DLIES--KD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIISP-----------------EYLSDEIFSAINNNLPHAYFKNLLFRLVANMDRSELSDLGTLIKDNLKRDLITSLPFEISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLLISENFVSPKGFNSLNLKLSQKYPKLSQQDRLRLSFLENIFILKNWYNPKFVPQRTTLRGHMTSVITCLQFEDNYVITGADDKMIRVYDSINKKFLLQLSGHDGGVWALKYAHGGILVSGSTDRTVRVWDIKKGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPKESSVPDHGEEHDYPLVFHTPEENPYFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQMKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLENIWNNGECSYATNSASPCAKILGAMYTLQGHTALVGLLRLSDKFLVSAAADGSIRGWDAN--DYSRKFSYHHTNLSAITTFYVSDNILVSGSEN-QFNIYNLRSGKLVHANILKDADQIWSVNFKGKTLVAAVEKDGQSFLEILDFSKASKINYVSNPVNSSSSSLESISTSLGLTRTTIIP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. . . : :: . * :. *: . .* : . : .: . . . . . . : * . . :: *. : . .... .* : : : * : : : . * .*: : ::: .: :*: :::**:*: ** *::* ::.:*: :*::.: ..: * ::: ... **:: . : . * : . : :::.: * ** . : .*:** ******* .* :::*:**: ::*:.::. * * * ** ****: : . *::*******::**: ..* * *.: **.*****:.: : :*:**** **:**.: . : ** **:*:** *. .*. :***:** : :*. **: *.***:*:** :* : :*.*:**:**:**:*. . :** ** :*.. :.* :::***. **.::: ** . : :.:. .: **:* : ....::::.*:: .:::::::*.::: : ::. .* :: : ..:. : *.. .:..:.* :. .: ", "identical_positions": 135, "similar_positions": 231, "identity": "9.65%" }, { "cls_id": "homologset.agr.SGD:S000001886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14683-1", "uniprot_id": "SMC1A_HUMAN", "id": "Q14683-1", "name": "Structural maintenance of chromosomes protein 1A", "aln": "-----------------------MGFLKLIEIENFKSYKGRQIIGP-FQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHG-----------APVGKPAANRAFVSMVYSEEGAEDRTFARVIVG--GSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA-ATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREI-EENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKG---AKLVIDVIRY--EPPHIKKALQYACGNALVCDNVEDARRIAFGGHQ-RHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKR-KEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRN-------SSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CU62-1", "uniprot_id": "SMC1A_MOUSE", "id": "Q9CU62-1", "name": "Structural maintenance of chromosomes protein 1A", "aln": "-----------------------MGFLKLIEIENFKSYKGRQIIGP-FQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHG-----------APVGKPAANRAFVSMVYSEEGAEDRTFARVIVG--GSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA-ATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREI-EENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKG---AKLVIDVIRY--EPPHIKKALQYACGNALVCDNVEDARRIAFGGHQ-RHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKR-KEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEESVSGSQRTSSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRN-------SSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1M9-1", "uniprot_id": "SMC1A_RAT", "id": "Q9Z1M9-1", "name": "Structural maintenance of chromosomes protein 1A", "aln": "-----------------------MGFLKLIEIENFKSYKGRQIIGP-FQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHG-----------APVGKPAANRAFVSMVYSEEGAEDRTFARVIVG--GSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQALKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNRQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA-ATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREI-EENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKG---AKLVIDVIRY--EPPHIKKALQYACGNALVCDNVEDARRIAFGGHQ-RHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKR-KEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGGSQGEESVSGSQRTSSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRN-------SSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920F6-1", "uniprot_id": "SMC1B_MOUSE", "id": "Q920F6-1", "name": "Structural maintenance of chromosomes protein 1B", "aln": "-----------------------MGHLELLLVENFKSWRGRQVIGP-FKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHG-----------AHTGKPVSSSASVTIIYIEDSGEEKTFTRIIRG--GCSEYHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNVKKNVAAERKHAKIEKEEAEHYQNLLEELKINKIQLMLFQLYYNEEKINVLNTELEQMDGNLSVVKDTLSHHENIFKAKKKDYGMLTRQLQQTAKELKSVEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDGIRALVAELADLDRAWKSFEKQMEEKILQKGRDIELENSQLDRYKLLKEQVRRKV-GIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGNLKQIKEQI-EEHKKRIEKLEEYTKTCMDCLEDKKQQEEALKKEIENTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQQKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKIAKDCIRFLKAERAEPETFLALDYLDIKPINERLREIKG---CKMMIDVIKT--QFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPE-RRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHNLRDKRSQLVQELKELMKTLR-KETDLKQIQTLVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDEVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNNIDTLKTTIQKGKEDIDNLKKTEEECLKIVEELMVKQEQIKEVLATQSSNIEKIHIQIEEERKKVLAVDREVGKLQKEVVIIQGSLEQKLLEKHNLLLDCKVQDIDISLVLGSLEDIIEMEL-TETESTQATAD----IYEKEASIQIDYSPLREDLKALQSDKEVEAHLTLLLQQVASQENTLLKTTAPNLRAQENLKTVRDKFQESADVFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRN-------NSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIIISLKEEFYSKADALIGVYPEHNECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRVPRVSMSPKSPQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE73-1", "uniprot_id": "D3ZE73_RAT", "id": "D3ZE73-1", "name": "Structural maintenance of chromosomes protein", "aln": "-----------------------MGHLELLLVENFKSWRGRQVIGP-FKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHG-----------AHIGKPVSSSASVTIIYVEDSGEEKTFTRIIRGRGGCSEFHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNRKKNVAAERKHAKIEKEEAEHYQSLLEELKTNKIQLMLFQLYYNEEKINVLNTELEHMDRNLSVVKDTLSHHENIIKAKKKDYGMLTRQLQQTAKELKSVEAVLNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCAKQEDGIRALVAELVDLDRAWRSFEKQMEEKILHKGRDIELENSQLDRYKELKEQVRRRV-GIMTQQLEKLQWEQKAEKERLAFERRRHGDTQGNLKQIKEQI-EEHKKRIEKLEEYTKTCMDCLEDKKQQEEALIKEIDNTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQRKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLREIKG---CKMMIDVIKT--QFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPE-RRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHSLRDKRNQLVQELKELMKTLR-KETDLKQIQALVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDKVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNKIDTLKTTIQKGREDIDNLKKTEEECLKIVEELMVKQEQVKEVLATQSSNIEKIHIQIEEERKKFLAVDREVGKLQKEVVIIQGSLEQKQLEKHNLLLDCKVQDIDISLMLGSLEDIIEVEL-TETESTQATAD----IYEKEASIQIDYSPLREDWKALQSDKEVEAHLTLLLQQVASQENTLLKTAAPNLRAQENLKAVRDKFQESADAFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRN-------NSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSGYIKEQSQEQFQMIIISLKEEFYSRADALIGVYPEHDECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRA-RVSQSPQSPQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NDV3-3", "uniprot_id": "SMC1B_HUMAN", "id": "Q8NDV3-3", "name": "Structural maintenance of chromosomes protein 1B", "aln": "-----------------------MAHLELLLVENFKSWRGRQVIGP-FRRFTCIIGPNGSGKSNVMDALSFVMGEKIANLRVKNIQELIHG-----------AHIGKPISSSASVKIIYVEESGEEKTFARIIRG--GCSEFRFNDNLVSRSVYIAELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKV-ATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQI-EDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKG---CKMVIDVIKT--QFPQLKKVIQFVCGNGLVCETMEEARHIALSGPE-RQKTVALDGTLFLKSGVISGGSSDLKYKARCWDEKELKNLRDRRSQKIQELKGLMKTLR-KETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATID----IYEKEEAFEIDYSSLKEDLKALQSDQEIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRN-------NSAQAFLSPENPEEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGQESSKRHGESR--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32THU2-1", "uniprot_id": "A0AB32THU2_DANRE", "id": "A0AB32THU2-1", "name": "Structural maintenance of chromosomes protein", "aln": "-----------------------MGFLKQLDVENFKSWRGKQTIGP-FKRFNCIIGTNGSGKSNVMDALGFVMGERAANLRVKHTRDLIHG-----------AHIGNPVSTFASVTMIYCGDNDEEMTFSRRISG--ESSEYLVNGKHVTLAKYTGELQKIGIVVKAKNCLVYQGAVESIAMMNAKERTKMFERISGSGDLNIEYDTKLAVLQKAKEDTQFHFNRKKAATAEKKQVFKDKTEAQRYQSLVDDLRECKLQLTLFQLFHNEKSIDAQSASLGDMQAAAAQQKISLDAWEQTVKTQKKEHGRLNRELQQLEKEIRSQEQILNQQRPQYIKAKVNTSHHEQKVQEAHRSLQKYQNLQAKKVQELEELKRELTELERAWKTSERQMEEEEARRGAGVQLQESQLERYKELKELARRNG-AILNQSAEKLHWEVKADREKLQFDLRRKSEIQGNIKHSQTHL-EDISRRAEKLEEYVNTTTQTLEEQRQQEEQLSEELAKGLLRMEEVNVELAQVLTKLQNARLDSQENRRQQKRDEVLESLRRLYPDTVYGRLVELCQPIHKKYQLAVTKVFGKNMNAIVVTSAYVAHDCIRYLKEERAEPETFLPIDYIDVPILNERLREVQG---AKMVVDVVQCSQNAPQLKRVIQYVCGNSLVCETLKDARRIAFDGPE-RLQTVALDGTLFRKSGVISGGSSDLSKKARRWEEKDMNKLKEEKDKLSSEMRALMKLKR-KEVDLKQIRAQSQGNQTRLKYANTELDSIRKKSIPAAQIEISKLRSELSNLEAQIEIQTGSMELKDSEMKAVKDKIHQMEDLVFADFCAEIGVANIREYEQDYLRLQQELEKKRLQFESQQTRLSTQLEYEQAQLGKLVKLMKKIEETIEKEKNIIISLKEGEDNILIAVEQTQSNLLKLNNQHSEKTHLVNNAKTELDKALTGLQERNKVLMKLQKQTISTDAALEHLRLTKHNLLLTCKIDGLPLTLISGALDDISEIQLDSESQS-VSTLD----IFEREAQMVFDFSALDNSLKMLTEESEVEAMLEKLKEGVSSLESMIMMSRAPNLKALDKIREVKDSYREVLDAFDISTITTKKRNQEFEQVKAKRFHLFSQCFEHVSVVIDQIYKKLCRN-------ASAQAILSAENPNEPYLDGINYNCVAPGKRFMAMDNLSGGEKAIAALALVFAIHSFRPAPFFVLDEVDAALDNTNIGKVTGFFRMMSRESCQIIVISLKEEFYSRADALLGVYSMFDECMFSRLLTLDLTPYPLNDENATDREKDK----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCD8-1", "uniprot_id": "Q9VCD8_DROME", "id": "Q9VCD8-1", "name": "Structural maintenance of chromosomes protein", "aln": "MTEEDDDVAQRVATAPVRKPDDETAFLEYIEMENFKSYRGHIVVGP-LKQFNAVIGPNGSGKSNFMDAISFVMGEKTSSLRVKRLNDLIHG-----------SSIGKPVSRSCYVTAKFVLNEERHMDFQRAVIG--GSSEYRINGESVSSSTYLNKLEKIGINVKAKNFLVFQGAVENIAMKTPKERTALFEEISGSGLLKDDYNRLKQEMIVAEEETQFTYQKKKGIAAERKEAKHEKMEADRYTRLQNEYNEKQVEYQLFRLFHVERDIRKFTSDLEVRQQEVKAVEQRKEAADEILREKKKDAGKITRDLAKIDQEIREFETQMNKRRPLYIKAKEKVTHCKKKLISLQKTLETAREADNAHQSDIRKLEKQLADVEALKKRFEDEIENESQRRGKSVNMEEGLVQEYDRLKQEAEATA-TQYRSELDSVNREQKSEQDTLDGETNRRASVEESFKKLTLQR-EEAVKRRDKLMDHIKSSQAALEEQNRIKDELRRDVGTSKEKIAEKQRELEDVRDQLGDAKSDKHEDARRKKKQEVVELFKKQVPG-VYDRMINMCQPTHKRYNVAVTKVLGKFMEAIIVDTEKTARHCIQILKEQMLEVETFLPLDYLQVKPLKERLRNISDPRNVRLVFDVLKF--EPQEIERAVLFATGNALVCETPEDAMKVAYEIDRSRFDALALDGTFYQKSGLISGGSHDLARKAKRWDEKHMAQLKMQKERLQEELKELVKKSR-KQSELATVESQIKGLENRLKYSMVDLESSK-KSISQYDNQLQQVQSQLDEFGPKILEIERRMQNREEHIQEIKENMNNVEDKVYASFCRRLGVKNIRQYEERELVMQQERARKRAEFEQQIDSINSQLDFEKQ--KDTKKNVERWERSVQDEEDALEGLKLAEARYLKEIDEDKEKMEKFKQDKQAKKQAVDDMEEDISKARKDVANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKTDCIVVPLLRGSLDDAVRQSDPDVPSTSAAMEN----------IIEVDYSSLPREYTKLKDDSAFKKTHEMLQKDLQSKLDVLERIQTPNMKALQKLDAVTEKVQSTNEEFENARKKAKRAKAAFERVKNERSSRFVACCQHISDAIDGIYKKLARN-------EAAQAYIGPDNPEEPYLDGINYNCVAPGKRFQPMNNLSGGEKTIAALALLFSTHSFHPAPFFVLDEIDAALDNTNIGKVASYIRDHTTN-LQTIVISLKEEFYGHADALVGITPGEGDCLVSNVYIMDLTTFEDT---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32908-1", "uniprot_id": "SMC1_YEAST", "id": "P32908-1", "name": "Structural maintenance of chromosomes protein 1", "aln": "-----------------------MGRLVGLELSNFKSYRGVTKVGFGESNFTSIIGPNGSGKSNMMDAISFVLGVRSNHLRSNILKDLIYRGVLNDENSDDYDNEGAASSNPQSAYVKAFYQKGNKLVELMRIISRNGDTSYKIDGKTVSYKDYSIFLENENILIKAKNFLVFQGDVEQIAAQSPVELSRMFEEVSGSIQYKKEYEELKEKIEKLSKSATESIKNRRRIHGELKTYKEGINKNEEYRKQLDKKNELQKFQALWQLYHLEQQKEELTDKLSALNSEISSLKGKINNEMKSLQRSKSSFVKESAVISKQKSKLDYIFKDKEKLVSDLRLIKVPQQAAGKRISHIEKRIESLQKDLQRQKTYVERFETQLKVVTRSKEAFEEEIKQS-ARNYDKFKLNENDLKTYNCLHEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRITEELSITGEKLDTQLNDLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRETMKERKLRENIAMLKRFFPG-VKGLVHDLCHPKKEKYGLAVSTILGKNFDSVIVENLTVAQECIAFLKKQRAGTASFIPLDTIETELPTLSLPDSQD---YILSINAIDY---EPEYEKAMQYVCGDSIICNTLNIAKDLKWKKGI-RGKLVTIEGALIHKAGLMTGGIS--GDANNRWDKEEYQSLMSLKDKLLIQIDELSNGQRSNSIRAREVENSVSLLNSDIANLRTQVTQQKRSLDENRLEIKYHNDLIEKEIQPKITELKKKLDDLENTKDNLVKEKEALQNNIFKEFTSKIGFT-IKEYENHSGELMRQQSKELQQLQKQILTVENKLQFETDRLSTTQRRYEKAQKDLENAQVEMKSLEEQEYAIEMKIGSIESKLEEHKNHLDELQKKFVTKQSELNSSEDILEDMNSNLQVLKRERDGIKEDIEKFDLERVTALKNCKISNINIPISSETTIDDLPISSTDNEAITISN------------SIDINYKGLPKKYKENNTDS----ARKELEQKIHEVEEILN-ELQPNARALERYDEAEGRFEVINNETEQLKAEEKKILNQFLKIKKKRKELFEKTFDYVSDHLDAIYRELTKNPNSNVELAGGNASLTIEDEDEPFNAGIKYHATPPLKRFKDMEYLSGGEKTVAALALLFAINSYQPSPFFVLDEVDAALDITNVQRIAAYIRRHRNPDLQFIVISLKNTMFEKSDALVGVYRQQ-QENSSKIITLDLSNYAE----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : :.****::* :* .*..:**.*******.***:.**:* : ** : .:**: * . : . : .. : . :.: ...: * * *:: .* :**:* **:** **.*: .. * : :**.:* * :*: : .:.: : :: .* : : :.* :. : *::*:: * . . .* : . . . .: *.. : .:: :: . * ::: .: : .: : : : :: : . * .:::. . . :: . :. *. *:: .. .: : : .: * .: : :.. *. : :.* . :: : * :: : : : :* :: : : :* :.:: * : ::: *. * . : ::*:* :::* :**:.::*: : :::* . .:.** :* : :*:.:* :: * : .. : .:.: . ::.: :. *:.::*:. : * : * . ::::*:: *:*:::** *::: .* :.: :: : * :. :. : : :: : : :: .: :. : . . .: . ::: :: * .:*. *:::*: .: :: :::.* : :*::. . : ::. : *: * : . : . :: . ::.. . : : . . :* : . * .* . : : : : * . : : .:: * .. . :. * : : . . : ** :* :. . . : : : * ::* .* * : :: :* **: * :* ..:* : :: :**: **.*:...* *** *: ****** :*****:*: :*::*:*******:***** **: ::: ::: * *:****: :: ::::*:*: : *.: :**: : ", "identical_positions": 169, "similar_positions": 393, "identity": "12.94%" }, { "cls_id": "homologset.agr.SGD:S000001887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9R9-1", "uniprot_id": "A0A0G2K9R9_RAT", "id": "A0A0G2K9R9-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDMVERILYSKTEHLRLNSFPN-------------------SIENVLKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAVSYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSE--YFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLQSFLQPELIKLQRCGDG-ELEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEHD------------------------------LSKENHREVIASVIRKLLS--HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADAVRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPAT---------VLAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIP------------EFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIIRLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQSHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSW2-1", "uniprot_id": "PSME4_MOUSE", "id": "Q5SSW2-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDLVERILYSKTEHLRLNSFPN-------------------SIENVLKTLVKSCRPYFPADSTAEMLEEWRPLMCPFDVTMQKAISYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSE--YFPVKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELIKLQCCGDG-ELEMSRDDILQSLTIVHSCLIGSGNLLPP--------------------LKGEAVTNLVPSMVSLEETKLYTGLEHD------------------------------LSRENYREVIASVIRKLLS--HILDNSEDDTKSLFLIIKIIGDLLHFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADALRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPTK---------ILAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMIEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIP------------EFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIICLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14997-1", "uniprot_id": "PSME4_HUMAN", "id": "Q14997-1", "name": "Proteasome activator complex subunit 4", "aln": "----------------------MEPAERAGVGEPPEPGGRPEPGPRGFVPQK------------------------------------------------------------------EIVYNKLLPYAERLDAESDLQLAQIKCNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPN-------------------SVENILKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYP--ALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMNDDVLND----EELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFDKPPSE--YFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELVKLQHCGDG-KLEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEYD------------------------------LSRENHREVIATVIRKLLN--HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADALRNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQ---------IIAGDRPDNHWLHYDSKTIPRTKKEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHE----STQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVP------------EFTARILEKLKPLMDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IAF6-1", "uniprot_id": "A0A0R4IAF6_DANRE", "id": "A0A0R4IAF6-1", "name": "", "aln": "--------------MTVSNIIEVEEPELENCNVKMKKEASELLG---FSPQK------------------------------------------------------------------DIVYNELLPYKDKLDDESNEILAQIKGNLGRAVQLREVWPGVLFWTR----------------------------------------------KLSTYIRLYGRKFNKE-------------------------------------DHVLFVKLLYELVTIPKLEISMMQSFARLLITLLKKKELLSREDLELPWRPLYELQDRILYSKTEHLGLNWFPSSLRPRSSSKHIIVKLAQRCSVEAVLKVLIKSCRPYFPESATQEMLDEWKPLMCPFDVTMQKAMGYFELFLPTTLPPELHDKGFKLWFDDLISLWVSVQNLPSWEVNLVSLFARLANDNIGYIDWDPYIPKIFTRILRSLNLPVGSSQMLVSRYLTNAYDIS--------YVVIWISALLGGPSKQAQTQLSGLFNGITSFFHPSNHGRWLMKLMKLLQRLPASVVKRLHRERYRTPTWLTPIPESHLLSEQDITDFVESIKQPVLLAMFSKTG--SLDAAQALQNLALLRPELVIPPVLEKTYP--AMETLIEPHQLTATLSCMIGVARSLVAGGQRFPEGPKHMLPLLMRALPGVDPNDFSKCMITFQFLATFVTLVPLVDCSSAIHSRNGLTQVEKELCSASAEFEHFVLQFVDRCFALIDTSTLEQTREEMEMEKMTHLESLVELGLSSTFSTILTQCSMEIFQVALDKVFNFATTSIFETHVAG----------RMVADMCRATTKCHPAEALKLFLPHCCSAILQIAANEEVLNE----EELDKELMWNLQLLSEVVRVDGDQLLLYRSQLVQILQLTLHLKCKQGYSLACKLLYHILRSMSLIYPREYCSIPGGIQQHTDT--YLPIQDWGRPGELWNLEIQWHVPSTEETEFVFYLLDLLLKPELQRLQKHTEG-QQDISRDDVLQSLSIVHNCFLGASSLLPP--------------------LHGEPVPQLINGMVQLYETKVYTGVDYD------------------------------MSRENYREDICKVIRPLLN--HTLEHSEDDIKSLFSIIKIINDLLHFKGSHKNEFDTR----------------WKSFNLIKKSMEN-------RLHGSKQHIRALLIDRVMLQHELRNLTMEGCSYRS----VHQDLINDLLRLSTSRYSQVRCRAQNVLFTALGTYNFCCRDIIPVVLKYLDPERTDVTQQQFKGALYCLLGNHSGIC---------LANLQYWDCIALTWPALVRSGMSPSMSLEKTSIVRLFDDLADKIHR-----------QYETISVNFSIPESCVEIAVKMLKSSSPEPNPGAASEQEELEGRKREEQKNKDAMQKYEKLVADLLDCLHDRNIPWKFEQLTIGFLSLMLRDDLPLP-SSAVLFFVESLNHDSLLVRNVAISAVAGILKQLKRPHKKVAVSPYDISELKTSLQSRDGKAVVSLLTGDRPDNQWLQYDSSRLPRSQRDWDECCFIEKTHWGYSTWPRKLMLYAPLEEQPKQGQTREEMNEREQIIYDHFSDQLFIDQFIQYLSLEDRKGKDKFSPRRFCLFKGLFRNFDDAFLPLLKPHMERLVADSHE----SPQRCVAEIISGLIRGSKHWSYSKVEK----LWALLCPLLRKALSNITIETYIDWGTCIATACESRDPRKLHWLFEMLMESPVTGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLQYLEPKLTQVYKNVRERIGSVLTYIFMIDVDLPYTQPTTSPRIR------------EFTERVLARLKPLTEGEEEIQNHIVEENMEGDQDERTQAIKLLKTVLKWLMTSAGRSFSSSVPEQLRLLPLLFKIAPVENDDSYDEMKTDAKTCLSLMSQGLLYSDQIPQVLSALEEISRSSSWHARYTILTYLQIMVFYNLFTFLSDAKAVCDVRALVLRLLEDEQLEVREMAATTLSGFLQCNFLSIDEPMQAHFESLSKTRLPKRKRRELGSVVDTIPSADLVRRHAGVLGLSACILSSP--YDVPTWMPQILMDLSAHLNDTQPIEMTVKKTLSDFRRTHHDNWQEHKQKFTDDQLLVLTDLLVSPCYYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA52Z1E4-1", "uniprot_id": "A0AA52Z1E4_DANRE", "id": "A0AA52Z1E4-1", "name": "", "aln": "----------------------------------MKKEQAEILG---FVPQK------------------------------------------------------------------EIVYNKLLPYADQLDRESNDILAQIKGNLGRAVQLRELWPGVLFWTR----------------------------------------------KLSTYLRLYGRKFSKE-------------------------------------DHVLFIKLLYELVTIPKLEISMMQSFARLLVNLLKKKELLSRDDLELPWRPLYDLYESILYSKTEHLGLNWFPN-YRAEASTKQKMLNIVRKRSVENVLKTLVKSCRVYFPESATQEMLDEWRPLLCPFDVTMQKAIGYFELFLPTIMPPEQHDKGFKLWFDEMMNLWVSVQNLPAWEGNLVNLFARLANDNIGYVNWDPYIPKIFTRILRSFNLPVGTSQMVVPRYLTNSYDIG--------HVVLWISSMLGGPQNQSQKQLNGLFSSIASFYHPSNNGRWLMKLMKLLQRLPASIVRRLHRERYKKPCWITPVPSTHKLTDQDVTDFVESMKQPVLMAMFSKTG--SMDAAQALQNLALMRPELVIPPVLEKTYP--AMETLTEPHQLTATLSCMIGMARSLLSGGRHYPEGPAHVLPLLMRALPGVDPNDFSKCMITFQFIATFTTLVPLVDCSSALHDKNDLTEMERELCSASAEFEDFVLQFMDRCFALIDSSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSMEIFKVALEKVFNFATTNIFETRVAG----------RMVADMCRAASKCHPAESLRLFVPHCCNAITHLTANEDVSNE----EELDKELLWNLQLLSEVTRVDGEKLLPYRTQLVQILQLTLRLRCKQGYSLACNLLHHVLRSTALIYPTDYCSVPGGFSRPLQE--YLPIKDWGRPGDLWNLEIQWHVPSTEETAFVFYVLDLLLQPELQRLQRYAQG-EQEMSRDDVLQSLCIVQHCLLGAGSMLPP--------------------LDGSTVTGLVPSMVNLEETKLYIGVDYD------------------------------QSRENYREAVCKVMRQLLH--YILEHSEDDTKSLFAIIKIISDLMHFKGSHKHEFDSR----------------WKSFTLVKKSMEN-------RLHGKKQHIRALLIDRVLLQHEMRKLLVEGCEYKT----VHQDLLRDLLRLSTSTYSQVRSKAQNVLFTALGTYNFCCRDITPRVLEFLEPTRTDVTQQQFKGALYCLLGNHCGVC---------LANLHDWDCIAQTWPAIVRSGLSSAMSLEKPSIVRLFDDLADKVHR-----------QYETIGIDFTVPENAVFLGRSITNSSQPTPHMSTPEDQELQQGLAVQQAKNREAEQKYEKLVKDLLECLDDRDLPWKFEHIAIGFLSLLLRDDYPLP-APAVFFFVQSLNHDALVVRKMAIAAVAGILKQLKRPRKKIPVNPCDISGVTEPEE---------LEAGDRPGNDWLQYHSESLPNSQQDWDAFCFVEKTHWGYYSWPKKLMVYAPAAEQPKD-LAPDTMSEREAIINDHFTDPMFINQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNYSDAFLPVLKPHMERLANDSHE----STQRCVAEIIAGLIRGSKHWSFGKVEA----LWAFLIPLMRTALSNITVETYADWGTCVATACESRDPRKLHWLLEMLMECPLSGEGGSFVDACHLYVLQGGLAQQEWRVPELLHRLLSYLEPKLTQVYKNVRERIGSVLTYIFMIDVALPYTLPTKSPHIA------------EFTERILTQLKPLIEGDEEIQNHVVEENGVGEQDERTQAIKLLKTVLKWLMASAGRSFSTPVPQQLQLLPLLFKIAPVENDDSYDELKRDAKTCLSLMSQGLLYPEQIPMVLAVLHEIAGSSSWHARYSVLTYLQTMVFYNLFTILSSEQCVQGVRALVIRLLEDEQLEVREMAATTLSGFLQCNFLAMDSSMQTHFEALCKTRLPKKRKRDVGSVMDTIPSVDLVRRHAGVLGLSACILSSP--YDVPTWMPQLLMDLSAHLNDTQPIEMTVKKTLSNFRRTHHDNWLEHKQQFTDDQLVVLTDLLVSPCYYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43583-1", "uniprot_id": "BLM10_YEAST", "id": "P43583-1", "name": "Proteasome activator BLM10", "aln": "MTANNDDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPHSPLRARSATPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIEEFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDLFRLSNNTAENDLLGNDIADYDDAEGLEDELDEYFDLAGPDFNATGKITAKSATIVNVNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTNFTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSS---------------KEDLQLFRLLLKHAHNAKPFFDKSKESLLVDTMNFLLS--SLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVSANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVGVEFGEFGIFTDDQMTFMFNRLQGHLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKFVHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYYISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIR-FIVMDKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLVQQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTKINQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSKELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELITFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDPRRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVLVMTHTLSGSSLLFDPDFNKYRTQSNLSYREKLILLKNIRENNCDPQELDIDIEQIRSGKDDEDYIESKDIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTPIAGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHKLYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNEPFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLY-PDIYKPAQGTLVHCMKQLVGSYGVVINKIIPSLEKAIKDHDYMKIQVILNVLLIKKIHRKLMTDYKDIGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINLQVEAVKLAKKKKREYYLSLLVDLQDKLLDKLD--NEKDMGWKIRMFILRFVTQIQSNLESKPDKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIIS----LSDYEYDITRAYKNEFN-----PSFVEILDTSTTSFPKTFTEEMNNFDN--PKYFIDLRAYVGWLCWGRLMYVMS-----PKALKLNLRENELEVLKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFELCESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFEIWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRAPDVGK---LFDELVFDHPYDQVRQAVAKLLTTLVQNQSNPSISDPTTLLEAERNDPDGLGLPLKSVPEKVDAYIKKQFEIIKNLEDSVVGLN--PQQFIKTDYFYRTSTIFYWIKEMARGPNKVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSSNVALSSNQTKLQLAFIQHFLSAELLQLTE-EEKNKILEFVVSNLYNEQFVEVRVRAASILSDIVHN--WKEEQPLLSLIERFAKGLDVNKYTSKE----RQKLSKTDIKIHGNVLGLGAIISAFPYVFPLPPWIPKQLSNLSSWARTSGMTGQAAKNTISEFKKVRADTWKFDRASFNTEELEDLEGVLWRSYYA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :: :::*** . . :. *.:: ** *:. :: : :: :*. *: * * .*. ::.*: ::.:.*:: :. * : .***.: .* * : : :: :* . :.. .: :* :..: :* . ::: . *:. .:: .. : : :. .. .. : :* .:* **. : :: .:.. ::.* . : . : .:. : .:.: .. . .: . * . . . :: :: *. .. :* .* ..* :* ****:* * *::: : * *:: *. . :* : .:::.::. : . .. . :.. * :* .. *: :* * * : : . *:: ::*. . : * :: .: : ::*.:*: * *.* *: : : :.:* .: *.. .. : ... : :: * :* : .: . :. : :: .**::.*..:: * :.* : : :*:**: .: : .. :. .:*: * : : .*. . :: . .. :: * :*: * *.:: * .** * :*: ::: : : .:: * : * : .: . : :: : : :* :******::* : : :*: : : : .:: .. . : . .*::*. :* :....:* *.. :.: :: * : : *: . : . :. : : ::* . . * :.* * .: :.:::. * : ::...:** *** * : * : *: :. : :: . ::: : . : : :. * * :.. * *: ** . . * :* : .: *:*.: : : : : * .:: . : : : .* **: * : : * :.:.:*.. :. . * . : . :. . . : : *: .:::: **:. : : ::: : : * *: ::..:. . : ::.: :: . ::: :. :*: : * . . : : :. : . .. : ::: *: * : : : : ** * * : . . : : ::*.: :. *.. ...:*. :: ...* : ..: .* . :: :. .**::**: ***. : .:: : :* : *.: :.* : . :.: : * .:.:. : ...: ::.::*:*:. * . *:*.*:: : : * : : *.:**: :..:** :. : . : ** ... :: :* : ::::: :: * :: :*: : .*:: *: * . . : * * * *. *::.: . *. : :. : .::. :: : . : * : *:::* :: :*: : . . :. :: * ::: :*** **: **.::: :..: :* :.* :: . * :: *..****.* : : * : :*.*:*: * :**: . . :.*:*:*:*::.: *.* .: .*. ::* * .:* . * ", "identical_positions": 228, "similar_positions": 676, "identity": "10.4%" }, { "cls_id": "homologset.agr.SGD:S000001889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61027-1", "uniprot_id": "RAB10_MOUSE", "id": "P61027-1", "name": "Ras-related protein Rab-10", "aln": "--------------------MAKK-------------TYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREH-GIRFFETSAKANINIEKAFLTLAEDILRKTPVKE--PNSEN----VDISS---GGGVTG-WKSKCC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61026-1", "uniprot_id": "RAB10_HUMAN", "id": "P61026-1", "name": "Ras-related protein Rab-10", "aln": "--------------------MAKK-------------TYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREH-GIRFFETSAKANINIEKAFLTLAEDILRKTPVKE--PNSEN----VDISS---GGGVTG-WKSKCC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35281-1", "uniprot_id": "RAB10_RAT", "id": "P35281-1", "name": "Ras-related protein Rab-10", "aln": "--------------------MAKK-------------TYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIEIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDQHANEDVERMLLRNKCDMDHKRVVPKGKGEQIAREH-RIRFFETSAKANINIEKAFLTLPEDILRKTPVKE--PNSEN----VDISS---GGGVTG-WKSKCC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15971-1", "uniprot_id": "O15971_DROME", "id": "O15971-1", "name": "", "aln": "--------------------MAKK-------------TYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEAIAREH-GIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQER----VIIDR---RNQEKAPGYSKCCA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P55258-1", "uniprot_id": "RAB8A_MOUSE", "id": "P55258-1", "name": "Ras-related protein Rab-8A", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDY-GIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITV---EQQKRT-SFFRCSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35280-1", "uniprot_id": "RAB8A_RAT", "id": "P35280-1", "name": "Ras-related protein Rab-8A", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDY-GIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITV---EQQKRT-SFFRCSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61006-1", "uniprot_id": "RAB8A_HUMAN", "id": "P61006-1", "name": "Ras-related protein Rab-8A", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDY-GIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITP---DQQKRS-SFFRCVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61028-1", "uniprot_id": "RAB8B_MOUSE", "id": "P61028-1", "name": "Ras-related protein Rab-8B", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDY-GIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITE---SRSKKT-SFFRCSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70550-1", "uniprot_id": "RAB8B_RAT", "id": "P70550-1", "name": "Ras-related protein Rab-8B", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDY-GIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITE---SRSKKT-SFFRCSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92930-1", "uniprot_id": "RAB8B_HUMAN", "id": "Q92930-1", "name": "Ras-related protein Rab-8B", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDY-GIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITE---NRSKKT-SFFRCSLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18338-1", "uniprot_id": "O18338_DROME", "id": "O18338-1", "name": "", "aln": "--------------------MAK--------------TYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQLAIEY-GIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMD---SRTKDS-WLSRCSLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DD03-1", "uniprot_id": "RAB13_MOUSE", "id": "Q9DD03-1", "name": "Ras-related protein Rab-13", "aln": "--------------------MAK--------------AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRQVQREQAEKLAREH-RIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGTNSKPS--STGLKT---SDKKK----NKCLLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35286-1", "uniprot_id": "RAB13_RAT", "id": "P35286-1", "name": "Ras-related protein Rab-13", "aln": "--------------------MAK--------------AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVEIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQREQAERLAREH-RIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGNSSKPS--STDLKV---SDKKNS---NKCSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51153-1", "uniprot_id": "RAB13_HUMAN", "id": "P51153-1", "name": "Ras-related protein Rab-13", "aln": "--------------------MAK--------------AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKEQADKLAREH-GIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPP--STDLKT---CDKKNT---NKCSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3A4-1", "uniprot_id": "RAB13_DANRE", "id": "Q7T3A4-1", "name": "Ras-related protein Rab-13", "aln": "--------------------MAK--------------KYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRKVSKETGEKLAKEH-GIRFFETSAKSSINVEESFTSLARDILLKSN-KKPGPSGR----EVKLTS---TEKKSS---SKCLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "--------------------MSGLRT--VSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKEL-GIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINS---GSGNSS--KSNCC--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P63012-1", "uniprot_id": "RAB3A_RAT", "id": "P63012-1", "name": "Ras-related protein Rab-3A", "aln": "--------------------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHL-GFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQL---TDQQAP-PHQDCAC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63011-1", "uniprot_id": "RAB3A_MOUSE", "id": "P63011-1", "name": "Ras-related protein Rab-3A", "aln": "--------------------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHL-GFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQL---TDQQAP-PHQDCAC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20336-1", "uniprot_id": "RAB3A_HUMAN", "id": "P20336-1", "name": "Ras-related protein Rab-3A", "aln": "--------------------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHL-GFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQL---SDQQVP-PHQDCAC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62823-1", "uniprot_id": "RAB3C_MOUSE", "id": "P62823-1", "name": "Ras-related protein Rab-3C", "aln": "------------MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQL-GFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQSTRL---KETPPP-PQPNCGC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62824-1", "uniprot_id": "RAB3C_RAT", "id": "P62824-1", "name": "Ras-related protein Rab-3C", "aln": "------------MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQL-GFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQSTRL---KETPPP-PQPNCGC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96E17-1", "uniprot_id": "RAB3C_HUMAN", "id": "Q96E17-1", "name": "Ras-related protein Rab-3C", "aln": "------------MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQL-GFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQNTRL---KETPPP-PQPNCAC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZT8-1", "uniprot_id": "RAB3B_MOUSE", "id": "Q9CZT8-1", "name": "Ras-related protein Rab-3B", "aln": "--------------------MASVTDGKTGIKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQL-GFDFFEASAKENISVRQAFERLVDAICDKMSDSMDT-DPSVLGASKTTRL---SDTPPL-LQQNCSC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63941-1", "uniprot_id": "RAB3B_RAT", "id": "Q63941-1", "name": "Ras-related protein Rab-3B", "aln": "--------------------MASVTDGNTGIRDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVIPTEKGRLLAEQL-GFDFFEASAKENISVRQAFERLVDAICDKMSDSMDT-DPSVLGASKTTRL---SDTPPL-LQQNCSC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20337-1", "uniprot_id": "RAB3B_HUMAN", "id": "P20337-1", "name": "Ras-related protein Rab-3B", "aln": "--------------------MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQL-GFDFFEASAKENISVRQAFERLVDAICDKMSDSLDT-DPSMLGSSKNTRL---SDTPPL-LQQNCSC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L986-1", "uniprot_id": "Q1L986_DANRE", "id": "Q1L986-1", "name": "small monomeric GTPase", "aln": "---------------------MAKADQRFGQRDGSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSSSFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESYNAVQDWATQIKTYSWDNAQVILVGNKCDMDEERVVPFEKGKHLADQL-GFEYYEASAKENINVRQVFERLVDIICVKMSERVDV-EPPMVTGAKTTRL---TDKPPQ-LPQNCC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35276-1", "uniprot_id": "RAB3D_MOUSE", "id": "P35276-1", "name": "Ras-related protein Rab-3D", "aln": "--------------------MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDL-GFEFFEASAKENINVKQVFERLVDIICDKMNESLEP-SSSPGSNGKGPAL---GDTPPP-QPSSCSC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63942-1", "uniprot_id": "RAB3D_RAT", "id": "Q63942-1", "name": "GTP-binding protein Rab-3D", "aln": "--------------------MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVSAEDGQRLAGDL-GFEFFEASAKENINVKQVFERLVDIICDKMNESLEP-SSSPGSNGKGPAL---GDTPPP-QPSSCGC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95716-1", "uniprot_id": "RAB3D_HUMAN", "id": "O95716-1", "name": "Ras-related protein Rab-3D", "aln": "--------------------MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDL-GFEFFEASAKENINVKQVFERLVDVICEKMNESLEP-SSSSGSNGKGPAV---GDAPAP-QPSSCSC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35283-1", "uniprot_id": "RAB12_MOUSE", "id": "P35283-1", "name": "Ras-related protein Rab-12", "aln": "MDPSAALHRRPAGG-SLGAVSPALSGGQARRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRNELSNSILSLQPEPEIPPELPPPRPHVRCC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35284-1", "uniprot_id": "RAB12_RAT", "id": "P35284-1", "name": "Ras-related protein Rab-12", "aln": "MDPSAALHRRPAGG-GLGAVSPALSGGQARRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRSELSNSILSLQPEPEIPPELPPPRPHVRCC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IQ22-1", "uniprot_id": "RAB12_HUMAN", "id": "Q6IQ22-1", "name": "Ras-related protein Rab-12", "aln": "MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPHVRCC--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::::**. .***:..: *: :* * : :*: :***::*: *:::**:********:.:**::***.* *::*:**::. .:: : .* :. : .. :: ** : * : . :. . : : *:*** . .: . * * * * * ", "identical_positions": 48, "similar_positions": 61, "identity": "19.51%" }, { "cls_id": "homologset.agr.SGD:S000001891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9U4-1", "uniprot_id": "F1M9U4_RAT", "id": "F1M9U4-1", "name": "MutS protein homolog 4", "aln": "MCSLRLRLRDGSTAHAPSLPPFQWHGFRPWGTRGLTRRASSVRKAREMLRQEATSLSSSPRWTPSRREVPRRRTPASASRPSTEGAVADRSSSSSSSS-PAPAA--APGSSFGNKRSYTTHKAASNFPVGTSSSSAQDTTYPHTFRTPLSAGNPQRS-YKGWTPQVGLSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFYGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKVALKN--CSTPLLRAYYGSLEDHRFGLILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMISQLAEKYSLPLRTSFSSARGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTFLKQIALCQIMAQIGSFVPAQYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGTGISYAVCEHLLSTKAFTLFTTHFLELCHIDTLYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKHYGLKAAEASSLPPSIVLDAREITTQITRQISQNRRSSPEMDRQRAVYHLATRLVQVARNSQLEPDRLRTYLSNLKKKYEGDFPRAADLPEKTEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MT2-1", "uniprot_id": "MSH4_MOUSE", "id": "Q99MT2-1", "name": "MutS protein homolog 4", "aln": "MCCLFLRLRDYSTAHALSLPPCQRCGLQPWSARSHARRTLGVRKAGEMLRQEAASLSSSPRWTPSRRDAPCGRTLASASRPSTEGAMADRSSSSSSS--PAPAS--APGSSFGNKRSYAIHRAASSFPVGTSSSSARDTTYPHTFRTPLSAGNPQRSGHKSWTPQVGYSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKN--CSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVLDARDITTQITRQILQNQRSSPEMDRQRAVYHLATRLVQAARNSQLEPDRLRTYLSNLKKKYAGDFPRAVGLPEKTEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15457-1", "uniprot_id": "MSH4_HUMAN", "id": "O15457-1", "name": "MutS protein homolog 4", "aln": "------MLRPEISSTSPSAPAVS-------PSSGETRSPQGPRYN--------FGLQETPQSRPS------VQVVSASTCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFST--VLMEVQSKYYCLAAVAALLKYVEFIQN----SVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKN--CNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T720-1", "uniprot_id": "A0AB32T720_DANRE", "id": "A0AB32T720-1", "name": "", "aln": "---MFCSSTEEVTAGSSSEPERS----------SSTLTPYNLMNY--------SQIFGRQQDPPS-------SSVLLTSRESDD-VRISVCPGSSSDTLPSALSETTPTAAQGHLN--ISETAYRTNSSGGSSAHSWTSSTPQLKTTPALS-HHSRTPRRDLNMTTSSSASAS--HAARAP-VIVAVVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT--VLMEVQTKYYCLASASALLKYFEFVQK----SIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHRSEHTLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQELLQNEELFFSLKNAIAHFLDIDELLSALVQIPKQETIAVAEAKITQVIQLKHIVELVPSLKVMLQH--STTHLLTAYCKSLEDCRFNSILDHIKSLINDDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGALPGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKINQKLWAKHHSDPATLKQRADYRLATRLVQTARNSQLDRASLRHYLKGLKTQYLAEIQMIKENATELVEIEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40965-1", "uniprot_id": "MSH4_YEAST", "id": "P40965-1", "name": "MutS protein homolog 4", "aln": "----------------------------------------------------------------------MSESNLSSFISTNYFNLRSAANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSMASRTATSLSRYSTNASLLGPSID--------CVLCCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDK-NGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCIN--HSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARVCN-DSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNS-----VKMNYQLTQKSVAIENSGIRVVKKIFNPDIIAEAYNIHSLLKIAKARTENEDSNGVVDQKTINQMKRIHNLVAILKECAGNEKEPLTLGKLKEINSDFIENFEE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .*.* *:. : . . . :. .: * : . : : . ..: . *: .: * .**:. *: : :: **:* *. * :*: **: * **::..:: . .. : : .*.: *: **. .** * : : : .. : *: : :.*.:.:* :.*.* : . .: * :.*:: *.*:*:* :**: :. .***: *: : . :*: .*: *.* *.* **..**:** : :*. * : ::** :::*: *: : : * ::*:* *: * .: .: :*. :: **. :: * .** ::. : *: ::: : * . *:: **:* : ...: : .*:.***:.: . :**::*: *.*: ::: : :* * .: * .:..:***::::. : : **. **. : ** . *: :::* * : :* :.:* :: * :**.:: :* *: :::.*::**:: *:: . .:*. * **:.* *::. **:**:: : . : ...*.. **** ******.:***:** ****:*. :** *.*. : ::.:*: *.:* .**.* ****::*::.: . .:*:::******:. :* :. :* *.*: :* .:::*** :: :: : *.: *::. :. . : .*:*:: .: *::..: * * . : : :... *:: :: .* .: . . .: :: ", "identical_positions": 184, "similar_positions": 321, "identity": "18.89%" }, { "cls_id": "homologset.agr.SGD:S000001894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX56-1", "uniprot_id": "D3ZX56_RAT", "id": "D3ZX56-1", "name": "ATP-dependent RNA helicase", "aln": "MEHVTEGSWESLQVP-LHPLVLGALRELGFLHMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKNQVGAIVITPTRELAIQIDEVLSHFTKH----FPQFSQILWIGG--RNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLASYVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRS--RQQEKHLVFFSTCACVEYYGKALEALVQR------VKILCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQEMS---------LQRNTVDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARGFALLRMPRMPELKGKQ--------FPDFVP--VDIDTDTIPFKDKIREKQRQKLLE-----------QKRKERTENEGRRKFIKNKAWSKQ---KAKKERKKKMNAKR----KKDEGSDIDDEDMEELLNDTRLLKKFKKGKITEEEFEKGLLTSTKRTVRLTESGVSDSEEDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPL9-1", "uniprot_id": "DDX55_MOUSE", "id": "Q6ZPL9-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MEHVTEGAWESLQVP-LHPRVLGALRELGFPHMTPVQSATIPLFMKNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKNQVGAIVITPTRELAIQIDEVLSHFTKH----FPQFSQILWIGG--RNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLASCVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRS--RQQEKHLVFFSTCACVEYYGKALEALLKK------VKILCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQEMS---------LQRNTIDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARGFALLRMPRMPELRGKQ--------FPDFVP--VDIDTDTIPFKDKIREKQRQKLLE-----------QKRKERSENEGRKKFIKNKAWSKQ---KAKKERKKKMNAKR----KKDEGSDIDDEDMEELLNDTRLLKKFKKGKITEEEFEKGLLTSAKRTVQLTDLGVSDLEEDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHQ9-1", "uniprot_id": "DDX55_HUMAN", "id": "Q8NHQ9-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MEHVTEGSWESLPVP-LHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKH----FPEFSQILWIGG--RNPGEDVERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFLRN--HKQEKHLVFFSTCACVEYYGKALEVLVKG------VKIMCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEESYINFLAINQKCPLQEMK---------PQRNTADLLPKLKSMALADRAVFEKGMKAFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQ--------FPDFVP--VDVNTDTIPFKDKIREKQRQKLLE-----------QQRREKTENEGRRKFIKNKAWSKQ---KAKKEKKKKMNEKR----KREEGSDIEDEDMEELLNDTRLLKKLKKGKITEEEFEKGLLTTGKRTIKTVDLGISDLEDDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHJ2-1", "uniprot_id": "DDX55_DANRE", "id": "Q8JHJ2-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MENITDGKWGSLPVK-LHDNILQTLKELGFTYMTPVQSACIPLFMSNKDVAAEAVTGSGKTLAFVIPALEILLKR---EEKLKKMQVGALIITPTRELAMQISEVMGRFLQG----FPQFTQILLIGG--SNPIEDVEKLKTQGANIIIATPGRLEDMFRRKADGLDLATAVKSLDVLVLDEADRLLDMGFEASLNTILGYLPKQRRTGLFSATQTQELEKLVRAGLRNPVRITVKEKGVAASSVQKTPAKLSNYYTMCRAEEKFNTLVAFLRQ--HKHEKQLVFFSTCACVEYFGKALEVLVKN------VSIHCIHGKMKH-KRNKIFADFRALKS-GILVCTDVMARGIDIPEVNWVLQYDPPSSASSFVHRCGRTARIGNQGNALVFLLPMEESYVNFLSINQKCPLQSFS---------SVKDVVDVLPKLKAMALGDRAMFEKGMRAFVSYVQAYAKHECSLIFRIKDLDFAALARGFALLRLPKMPELRGKT--------FPDFKA--EAIDTDTIRFKDKNREKQRQKWLA-----------EQKEK--EVPLRKNFIKNKAWSKQ---KIKKDRKKKRLPKA----KLDQDSDAAEEDLNELMNDTRLLKKLKKGKITEEDFDKQMSSTDKHKP----AGIDSSDGD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHU1-1", "uniprot_id": "DDX55_DROME", "id": "Q9VHU1-1", "name": "Probable ATP-dependent RNA helicase DDX55 homolog", "aln": "---MSRKKWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQRRHK-ETPWGPKEIGALVISPTRELARQISEVLAQFLEHE--DLEHLNQQLIVGG--NSIEEDIATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEK-----ASVNTPARLQNFYRIVEPELKFVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPK------RTVLGIHGKMKN-KRANVVEKFRNTPQ-AVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQ--------GGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGKGKKRQQFSQEDLDELASDIRLFKRLKKNKISEEDFDKAMGIEGNND---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25808-1", "uniprot_id": "SPB4_YEAST", "id": "P25808-1", "name": "ATP-dependent rRNA helicase SPB4", "aln": "--MSKSLEWDNLGFS-LLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEKVVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVLDFLQMP------AVKTSACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSK-------NQAPSSLKLNYCVVNPAEKLQLLVSILNN--YKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTDSLSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELD-------LEVKGITTNFYEDFRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLATEKQEGIFPGNWLVDPPVNMDEYKYKDKKREKERQETLKN----------ISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLK----RKAIEEELKAEELDENAEEERIKEDWKEIVLQNKRKKVSSKAIQGNFDDL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .* * : : :** *****:: **:: .*** .::******* **::* ** : :. .. :::*:*****: **..*: * : : :. * :* . :*: : . *:: ****: *::: * . : ..:*:********:.* . :.** **:********** .:.::****** ::*:.* ::*: *. * : .. *: *: :* . * :*:*.**..*.*: . : * : :***:: * : . * . .:*. *** ***:*:*::: *:* ***:.:. *:** ***.* .. *.*:.** .: . : :: * .: . .:: *: ::**::*:*:.:: *::*... *:*::.** :* :.*:::*:***: . :: . :*: :*: **: : . : : * * *.: * :* .:* : .: *:::* .: *: : *: : :: . . ", "identical_positions": 155, "similar_positions": 185, "identity": "23.59%" }, { "cls_id": "homologset.agr.SGD:S000001895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI38-1", "uniprot_id": "PUS3_MOUSE", "id": "Q9JI38-1", "name": "tRNA pseudouridine(38/39) synthase", "aln": "------------------------MAEN-TDRNQIEKLLNRVKELEQEVERLKKKKEQANNIKDSSIRENSLGSG-----------------KAKRAFDFSAHGRRHVALKIAYLGWGYQGFASQENTS--NTIEEKLFEALTKTRLVESRQTSN--YHRCGRTDKGVSAFGQVISLDLRSQFPTSRDSEDSNLKHEADDLAKEIRYTHILNRVLPADIRVLAWAPV-EPSFSARFSCLERTYRYFFPRADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILCAQVQLVAQSPGEERRQEPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIQKNPQKPQYSMAVEFPLVLYDCKFEN-TKWIYDHEVQEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKMDEAT--EWR--NIQPPVIKHTSAFVEGVKMRTYKPLMDRPKCQGLESRIRHFVSRGRIEHPHLLHKEEIKARRDCAD--KEENTVVENPSKRVCIIDAEINSIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE2-1", "uniprot_id": "PUS3_HUMAN", "id": "Q9BZE2-1", "name": "tRNA pseudouridine(38/39) synthase", "aln": "------------------------MAYNDTDRNQTEKLLKRVRELEQEVQRLK--KEQAKNKEDSNIRENSAGAG-----------------KTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTN--NTIEEKLFEALTKTRLVESRQTSN--YHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPV-EPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQLVGQSPGEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFEN-VKWIYDQEAQEFNITHLQQLWANHAVKTHMLYSMLQGLDTVPVPCGIGPKMDGMT--EWG--NVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCNDTLEEENTNLETPTKRVC-VDTEIKSII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W282-1", "uniprot_id": "Q9W282_DROME", "id": "Q9W282-1", "name": "Pseudouridine synthase I TruA alpha/beta domain-containing protein", "aln": "-------MSATNDKKVVINKRLKGLSREALEKLTQTELIDKVIQLEAYNFQLRNLLQKKLSEKDKHDKEYSGLIGNEAEGKVSQVAKTSSKVQKIRKFDWSSAHKRHVLLKITYFGWDYQGFACQEDSN--DTIESNLFRALARTCLIESRATSN--YHRCGRTDKEVSAFCQVISIDLRSKHPP--ESQ-----LDPTALSSEIDYCGLLNRVLPKNIQCVAWMPLRSPVYSARFDCVSRTYRYYFPKGDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQTN---HTNSGYDMYYLEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVESNPCKPQYTPAIGLPLNLFRCDFRDHTTRSVNHPSSGDADEEAMDTAADESNDLNAPEHLERDLTAWIYNEENLQKLIENTQCEWTQFSVKSTMIRNVLQQLENLFEENFK-----PKEKVLAQVILLQDSVNPRQYQPLLERKRCES---------LENRIEHFVKKQRLIVKNETETE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31115-1", "uniprot_id": "PUS3_YEAST", "id": "P31115-1", "name": "tRNA pseudouridine(38/39) synthase", "aln": "MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRS--------------KAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRD-------PTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETF-----------YCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPE----------MDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCN-----------------------IFKDVLPTAN--------------TNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEP------------VEVVNAKYSKKKNNKNK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :*: :: :** :: . :. : . . : : **:* *.: *:::*:**.*:*:* *:: . *:* .::.*: : *: * .: : ******* ***: ****:::**: . : : . : ** * :**::** :*: * * :.***.*: * *:* * :*:* * *.. * ****:**:* : : *: *.: .::: :: ::: ..***:**:**:**:*:*:** * * :: * :::..* :* * * :** *: *.* : : * . : * : :::.. : . : * . : ... . . : . : :. ", "identical_positions": 96, "similar_positions": 125, "identity": "17.94%" }, { "cls_id": "homologset.agr.SGD:S000001898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HC5-1", "uniprot_id": "NUP93_RAT", "id": "Q66HC5-1", "name": "Nuclear pore complex protein Nup93", "aln": "------MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETAD---VKASVLLGSRGLDISHISQRLESLSAATTFEPLEP--VKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGE-DALDFTQESEPSYVSDVSPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCAS-VAE--LDDKSISDMWAMVKQMTDVVLTPAT-DALKSRSSVEVRMD-FVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAP-SPGLQDGEV--EGHPVWALIYYCMRCGDLLAASQVVSR----AQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRN--NTDPYKRAVYCIIGRCDITDNQS-EVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGE-NMFLRCVSELVIES-----REFDMILG--KLENDGSRKPGVIDK------FTS---DTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKN-------MALSIAERYRAQG---ISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQES-MEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSAT----RPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ71-1", "uniprot_id": "NUP93_MOUSE", "id": "Q8BJ71-1", "name": "Nuclear pore complex protein Nup93", "aln": "------MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETAD---VKASVLLGSRGLDISHISQRLESLSAATTFEPLEP--VKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGE-DALDFTQESEPSYIGDVNPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCAS-VAE--LDDKSISDMWAMVKQMTDVVLTPAT-DALKSRSSVEVRMD-FVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAP-SPGLQDGEV--EGHPVWALIYYCMRCGDLLAASQVVSR----AQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRN--NTDPYKRAVYCIIGRCDITDNQS-EVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGE-NMFLRCVSELVIES-----REFDMILG--KLENDGSRKPGVIDK------FTS---DTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKN-------MALSIAERYRAQG---ISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQES-VEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSAT----RPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1F7-1", "uniprot_id": "NUP93_HUMAN", "id": "Q8N1F7-1", "name": "Nuclear pore complex protein Nup93", "aln": "------MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETAD---VKASVLLGSRGLDISHISQRLESLSAATTFEPLEP--VKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGE-DALDFTQESEPSYISDVGPPGRSSLDNIEMAYARQIYIYNEKIVNGHLQPNLVDLCAS-VAE--LDDKSISDMWTMVKQMTDVLLTPAT-DALKNRSSVEVRME-FVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAP-LPGLQDGEV--EGHPVWALIYYCMRCGDLLAASQVVNR----AQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRN--NTDPYKRAVYCIIGRCDVTDNQS-EVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGE-NMFLRCVSELVIES-----REFDMILG--KLENDGSRKPGVIDK------FTS---DTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKN-------MALSIAERYRAQG---ISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLVPLNQES-VEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSS----RPQRVIEDRDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZU29-1", "uniprot_id": "NUP93_DANRE", "id": "Q7ZU29-1", "name": "Nuclear pore complex protein Nup93", "aln": "------MDTEGFGELLQQAEQLAAETEAVSELPHVERNLQEIQQAGERLRSRTLTRTSQDTAD---VKASILLGSRGLDIFHISQRLESLSAATTFEPLEP--VKDTDIQGFLKNERDNALLSAIEESRRRTFLLAEEYHRDSMLVQWEQVKQRVLHTLLGAGE-DALDFSQEVEPSFVSEVGVPGRSALDSVEVAYSRQIYVFNEKIVNGHLQPNLGDLCAS-VAES-LDDKNVSEMWLMVKQMTDVLLVPAK-DTLKSRVSVDMQMA-FVRQALQFLENSYKNYTLVTVFGNLHQAQLGGVPGTYQLVCSFLNIKLPTP-LPGRQDGEV--EGHPVWALIYFCLRCGDLSAAMQVVNK----AQHQLGDFKIWFQEYMNSPDRRLSPATENKLRLHYRRVLRN--SADPYKRAVYCLIGKCDIGDNHG-EVADKTEDYLWLKLNQVCFDEDGSSSPQDRMTLAQLQKQLLEDYGESHFSASHQPFLYFQVLFLTAQFEAAIAFLFRVERLRSHAVHVALVLYELKLLLKSSGQSAQLLSQEAGDPPMVRRLNFIRLLMLYTRKFESTDPREALQYFYFLRNEKDSQGE-NMFMRCVSELVIES-----REFDMLLG--RLEKDGSRKPGVIDK------FAG---DTRAIITKVASEAENKGLFEEAVKLYELAKNADKVLELMNKLLSPVIAQVSEPQSNKERLKN-------MAVAIAERYRANG---VAGEKSVDNTFYLLLDLMTFFDEYHAGHIDRAYDVIERLKLVPLSQDS-VEERVAAFRNFSDEVRHNLSEVLLATMNILFTQYKRLKGAAAGTPG----RPQRTLEDRDMLLRIQARALITFAGMIPYRMAGDTNARLVQMEVLMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ06-1", "uniprot_id": "NU931_DROME", "id": "Q9XZ06-1", "name": "Nuclear pore complex protein Nup93-1", "aln": "---------MDLMELLKQAQRLTNETNTDTEVPGVERTMSQVLQATKEFHSR---VTQMGTND---LQAHILLGSKGVDLPKLTQKLESLSARQTFEPIDP--VTETNVQAYLKNERENAILSVIDETNRSIFKSVERQKWRCIYSEWGEEKEALLNALVGPNQQDFPDVQFQIVPTAMADEPTP-YSQLNGHEQMYAEQIAIHNQSIILG-RRPNLLSTLAH-VVQDSFNDESVAEMWNVLQFMTALPPVSSTIDPIKNR---QTSPQ-FVEQARTYLERRYRTYMRKFIVANLAKARRGGIPSVYHMVRSYVGVTLQGQRALYGLHDVN--NGQPLWPHVYYSLRSGDMDAAALYLKE----SGTCP-DLLTLLTLRKNGDRDNLMVKLEGQLKLEYNSRLRA--CTDPYKKAVYVVLLACDPHFTHV-ELMRSIDDFLWMQLSILRRS-DQSDSNTEQLTFSGLQSLILEKYGENYFNAREKAALYFQVLTLTGQFEAAIEFLARTEKNRTHAIHMAIALNEISMLGTPRSVEQSLLSSDPDDPKPMKRLNLVRLIVMYTKCFERTDTTQALHYYYLLRNFKSENGRGNVMLTCVCDLLVEK--CDDEMLELIFG-TEDKKNGLRYGGIYAE------FQIHECDKYSLAEMVGDELSKRGDYELAIELYFIGGQLDKALRLVNSLLAQVVHQPTQNGSVRNRLGD-------IINRLDAALVVRK---SDVEVQVVVTYTVLTKVMKFFDHYHEGALRSALEILTNNHLIPASSLE-VDECVTNIKRMGPEVIKVLPDILLASMDIVYQEYVKLMDSNETASGFFDESKCVNKEPAVKHLRDRAKAFTNMAASVPYRMPSTTNQRLVQLEILMH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE7-1", "uniprot_id": "Q9VFE7_DROME", "id": "Q9VFE7-1", "name": "Nuclear pore protein", "aln": "---------MDLNTLLQRAQNLNNDAKAECELPAVERTLQQVLRATTELHSR---VTQTGCKE---IQAHILLGSKGVDLPKLNQKLEALSARKTFEPLDV--KADTDVRTFLKNERENAILSVIEDTKKNISDSANKQRWASMNKVWNEEKTRLLDALIAPSQ-NFIDLQRLPEPTIVNPLCQP-RSCLDPLELVYAQELRHYNELLLKSSHRPNLVQKFAH-LSQS-FGDCRLTDMWTLLACVTQIS-EPLRSDPIKSR---QQRPE-FVTYAKSYLERRYRVFMCSQVGGSYANN-------SYQLVVAYVNHRFRAQQTIG-LVDTV--REIPLWPLVYYGLRCGAVKVAVEFLRE----AGSSH-DEFAQLVADRNAGETN--SKIENQLRLQYANKIRN--STDAYKKAVYCILLGCDVNEVHG-EVAKTIDDFLWMRLAMIQPG-DADN-------YGKLQSMILEQYGEKYFNARQQPYLYFETLALTGQFEAAIEFLARQDENRAHAVHMAIALFELGLLGSARSVSQPLLSIDIKDPQPLRRLNLTRLIRQYVQRFERTDTSEALHYYYTLRCLKDSKGR-NMFMACVCDLVVDSGVFDTTIFDLIFGKRQSSDQNDVNSGLFRQ------FECPEFDTRTMAAQVGDELAALGNFEMSARLYEMAGKYNLAVKHICILMAQVVHLPTLGGSLRERLGQ-------DAQRFNQLLASDS---IDVEPKMKSSFVLLQDLLIFFNFYHDGKFNAALDLLRQTQLVPNTLDD-VDVVLGNVKQLSGEVIKVLPDVIVAAMEIAQKQYKQLKAGSGSS----------LEQTQMQQLRQRAKALSNMAATMPYRLPNDTNKRLIELELDMH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34077-1", "uniprot_id": "NIC96_YEAST", "id": "P34077-1", "name": "Nucleoporin NIC96", "aln": "MLETLRGNKLHSGTSKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASKDYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIRTKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQ-DKKTVDHKKSISSLDPKLPSWGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEG----LATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFYLLRAGLIKEALQVLVENKANIKKVEQSFLTYFKAYASSKDHGLPVEYSTKLHTEYNQHIKSSLDGDPYRLAVYKLIGRCDLSRKNIPAVTLSIEDWLWMHLMLIKEKDAENDPVYERYSLEDFQNIIIS-YGPSRFSN-----YYLQTLLLSGLYGLAIDYTYTFS--EMDAVHLAIGLASLKLFKIDSSTRLTKK--------PKRDIRFANILANYTKSFRYSDPRVAVEYLVLIT-LNEGPTDVELCHEALRELVLET-----KEFTVLLG--KIGRDGARIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYDSILLYQLAEEYDIVITLVNSLLSDTLSASDLDQPLVGPDDNSETNPVLLARRMASIYFDNAGISRQIHVKNKEICMLLLNISSIRELYFNKQWQETLSQMELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIITLSCISNMIHILNESKYQSST---------KGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVSL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* : ::* .. : .: : .:: * . . :* **.. *:.: .: :: *.: :** . ::. :::.:::: :* *:: . :. : * : * ::. : : : . : : . . : .: :: :: . . .: ::: : : : . :. * . :* . :**. : : . : : : :::. : . . *:*. ::: :*.* : * : . . : .. . :*: .* :: *.*: *** :: ** : : . :*:**::* : . :*. ::. ** . *. *::.* *:. : *: : . . .*:*:*: * .: :: . : :.: .:: *.: *. :*. *:.* : :. :: .: :*:::. : :::* . :. *: : . .: .. * : ** :. : : .: : *:: .: . : : . :* .: : : *. : . : .*:* . . .:. :: : :.:::: ::. * : *: *: *. : ** . * *::::: : ", "identical_positions": 72, "similar_positions": 253, "identity": "8.2%" }, { "cls_id": "homologset.agr.SGD:S000001899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60927-1", "uniprot_id": "PP1RB_HUMAN", "id": "O60927-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "--------------------------MAEAGAG-LSETVTETTVTVT-----TEPENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEEEEEGCGH------------------THCVRGHRKGRRRATLG---PTPTTPPQPPDPSQPPPGPMQH------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K1L5-1", "uniprot_id": "PP1RB_MOUSE", "id": "Q8K1L5-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "--------------------------MAETGAG-ISETVTETTVTETTVTETTEPENQSLIMKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCSH------------------KHCVRGHRKGRRPTTPA---PTPTTPPQPPDPSQPPPGPMQH------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MFY6-1", "uniprot_id": "PP1RB_RAT", "id": "Q6MFY6-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "--------------------------MAEAGAGGLSETVTETTVTVT-----TEPENRSLTIKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCGH------------------THCVRGHRKGRRPTTPG---PTPTTPPQPPDPSQPPPGPMQH------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q568K2-1", "uniprot_id": "PP1RB_DANRE", "id": "Q568K2-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "--------------------------MAEVPGT-SSETITETVQTGTP--PPPQQEGRSLTIKLRKRKTEKKVEWSSDTVDNEHLGRRSSKCCCIYEKPRQFGESSSESEGDDEEGCGS------------------AHCILGHGRRGHGQREG---GGTTVPP-------SSGGTNPH------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMI2-1", "uniprot_id": "Q9VMI2_DROME", "id": "Q9VMI2-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "-------------------MAHKQSTNNETSNGSTTEIIDETDARAQLE---SGRTTPTLLLRLEHPRNERRVAFHAGIIDNEHLNRKKSKCCCIYKKPLAFGESSSEDDEDCEHCFGHPEK-------------RQRNAKHNHNHGDKPCTEASHPEGPSTSTQAAHISQPPAEPVESKTDPKPPTPGVDFEQTGSS-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRC5-1", "uniprot_id": "Q9VRC5_DROME", "id": "Q9VRC5-1", "name": "E3 ubiquitin-protein ligase PPP1R11", "aln": "MDSNCDLSMVNGQTEPKDPKWASSSTQITSRASETFSGVGSAISTETSLQPVAAPTMYCLRLAQQRPITERHVHFHAGVIDNEHMNRRKSKCCCIYRKPHPFGESSSSTDDECEHCFGHPEVRTRNRLEKQRIQEQQNGCSCCHHHHRLHSNRNNRPPTEEIAQHKDDLAKEEPKSVVNNESSLKLLNEENVKSSKPEKKNNSNNRLEVTFVELD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43587-1", "uniprot_id": "YPI1_YEAST", "id": "P43587-1", "name": "Type 1 phosphatases regulator YPI1", "aln": "----------------------MSGNQMAMGSEQQQTVGSRTVSVEEVPAVLQLRATQDPPRSQEAMPTRHNVRWEENVIDNENMNKKKTKICCIFHPQNEDEEECNHHSDDDGSSSSG------------------SSSSESENEKDLDFNERRQRRLERRHRKLEKKRSYSPNAYEIQPDYSEYRRKQQEKKD--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:.* : . :***::.::.:* ***:. *... . : . . . . . ", "identical_positions": 9, "similar_positions": 27, "identity": "4.19%" }, { "cls_id": "homologset.agr.SGD:S000001900", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00487-1", "uniprot_id": "PSDE_HUMAN", "id": "O00487-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35593-1", "uniprot_id": "PSDE_MOUSE", "id": "O35593-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZJ1-1", "uniprot_id": "A0A0G2JZJ1_RAT", "id": "A0A0G2JZJ1-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V3H2-1", "uniprot_id": "PSDE_DROME", "id": "Q9V3H2-1", "name": "26S proteasome non-ATPase regulatory subunit 14", "aln": "MDRLLRLGGAMP--QAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLEDEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43588-1", "uniprot_id": "RPN11_YEAST", "id": "P43588-1", "name": "Ubiquitin C-terminal hydrolase RPN11", "aln": "MERLQRL--MMN--SKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ** * .:*: ** * *****:*******************************.*:*******:********** ******:******** :*****************.**:***:*** *..*************************:.. :: . ******** * *:*..:*************:.*:*:*. * ***:****:.* .**.: **.*: . * .. .*:.:*::*.* :*:*.::* *:* : **:****:**.* .* : .***. * * ::::.:*", "identical_positions": 196, "similar_positions": 68, "identity": "63.23%" }, { "cls_id": "homologset.agr.SGD:S000001901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TIX9-1", "uniprot_id": "UBP39_MOUSE", "id": "Q3TIX9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 39", "aln": "MSSRSKRQSHGSTRGKRESESRGSSGRIKKERDREKEPEAASSRGSPVRVKREAEPA-AREVPAPALPVVRVKREREADEDSEPEREVRAKNGRVDSEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHINAYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYEIIDS----SLEDITYVLKPTFTKQQIANLDK-QAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVNDVFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYKENFLKRFQLTKLPPYLIFCIKRFTKN--NFFVEKNPTIVNFPITNVDLREYL-SEEVQAVHKNTTYDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRRDNDETNQQGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GV41-1", "uniprot_id": "B2GV41_RAT", "id": "B2GV41-1", "name": "Ubiquitin carboxyl-terminal hydrolase 39", "aln": "MSSRSKRQSHGSTRGKRESESRGSSGRIKKERDREKEPEAASSRGSPVRVKREAEPT-PREVPAPVLPVVRVKREREADEDSEPEREVRAKNGRVDSEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHINAYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYEIIDS----SLEDITYVLKPTFTKQQIANLDK-QAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVNDVFQGSMRIFTKKLPHPDLPAEEKEQLLHNEEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYKENFLKRFQLTKLPPYLIFCIKRFTKN--NFFVEKNPTIVNFPITNVDLREYL-SEEVQAVHKNTTYDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRRDNDETNQQGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53GS9-1", "uniprot_id": "UBP39_HUMAN", "id": "Q53GS9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 39", "aln": "MSGRSKRESRGSTRGKRESESRGSSGRVKRERDREREPEAASSRGSPVRVKREFEPASAREAPASVVPFVRVKREREVDEDSEPEREVRAKNGRVDSEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHINAYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYEIIDS----SLEDITYVLKPTFTKQQIANLDK-QAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVTDVFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYKENFLKRFQLTKLPPYLIFCIKRFTKN--NFFVEKNPTIVNFPITNVDLREYL-SEEVQAVHKNTTYDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRRDNDETNQQGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWP1-1", "uniprot_id": "Q9VWP1_DROME", "id": "Q9VWP1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 39", "aln": "--------------------------------------MAQTQAPAAKRMKLEKTPA------------------NPVEEDETP-----------SVFNPKYRVCPYLDTINRNLLDFDFEKLCSISLTRINVYACLVCGKYFQGRGTNTHAYTHSVGEAHHVFLNLHTLRFYCLPDNYEIIDS----SLDDIKYVLNPTFTRQEISKLDQLQPKHSRTVDGVLYLPGVVGLNNIKANDYCNVVLHALSHVGPLRDYFLQKQSYAHVVRPPGDSVFTLVQRFGELMRKMWNPRNFKSHVSPHEMLQAVVLWSSKRFQITEQGDPIDFLSWFLNTLHRALKGNKHPNSSILYKIFLGEMKIYTRKMPPVELDDAAKAQLLATEEYKDQVEDKNFIYLTCDLPPPPLFTDEFRENIIPQVNLYQLLSKFNGTAEKEYKTYKANFMKRFEITRLPQFIILYIKRFTKN--TFFLEKNPTIVNFPIKHVDFGDILGMRQRDKDVKDTKYNLVANIVHDGDPKKGTYRAHILHKANGQWYEMQDLHVTEILPQMITLTESYIQIYERCPNSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43589-1", "uniprot_id": "SAD1_YEAST", "id": "P43589-1", "name": "Pre-mRNA-splicing factor SAD1", "aln": "------------------------------------MEVDNKRRHSEDELKQEAVKK----------------------------------------IKSQEPNYAYLETVVREKLDFDSEKICCITLSPLNVYCCLVCGHYYQGRHEKSPAFIHSIDENHHVFLNLTSLKFYMLPQNVQILHDGEVQLLNSIKFAAYPTYCPKDLEDFPR----QCFDLSNRTYLNGFIGFTNAATYDYAHSVLLLISHMVPVRDHFLLNHFDNQGE---------FIKRLSICVKKIWSPKLFKHHLSVDDFVSYLKVREG---LNLNPIDPRLFLLWLFNKICSSS----NDLKSILNHSCKGKVKIAKVEN-----------KPEASESVTGKVIVKPFWVLTLDLPEFSPFEDGNSVDDLPQINITKLLTKFT-------KSRSSSTSTVFELTRLPQFLIFHFNRFDRNSDHPVKNRNQTLVEFSS-ELEILHVKYRLKANVVHVVIKQPSTDGNAFNGD-EKSHWITQLYDNKSEKWIEIDGINTTEREAELLFLKETFIQVWEKQE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:* * . : .**:*: *. **** **:*.*:*: :*.*.*****:*:*** :: *: **: ******* :*:** **:* :*:.. *:.*.:. **: ::: .: : . .. ** *.:*:.* : **.: ** :*:: *:*::** :. : :::*:. ::*:*.*: ** *:* .:::. : : . : * ** *::* : : : .:*: . *.::* . : : .:. : . * ** *** . : * :**: : ::*:**. *: . . . *::*:** ::*: ::** :* . ::* *:*:*. .::: . : : . . ..:*. .:. : :: .: . :* *::.::.*: .::: *.*::**:::: ", "identical_positions": 110, "similar_positions": 170, "identity": "19.2%" }, { "cls_id": "homologset.agr.SGD:S000001902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0D7-1", "uniprot_id": "PEPD_RAT", "id": "Q5I0D7-1", "name": "Xaa-Pro dipeptidase", "aln": "MASTVRPSFSLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--GAVQAGSAVVLQGGEEMQRYCTDTSIIFRQESFFHWAFGVIESGCYGVIDVDTG----KSTLFVPRLPASYATWMGKIHSKEHFKEKYAVDDVQYADEIASVLTSRNPSVLLTLRGVNTDSGNVCREASFEGISKFTVNNTILHPEIVECRVFKTDMELEVLRYTNRISSEAHREVMKAVKVGMKEYEMESLFQHYCYSKGGMRHTSYTCICCSGENAAVLHYGHAGAPNDRTIKDGDICLFDMGGEYYCFASDITCSFPANGKFTDDQKAIYEAVLRSCRTVMSTMKPGVWWPDMHRLADRIHLEELTRIGLLSG--SVDAMLQVHLGAVFMPHGLGHFLGLDVHDVGGY-PEGVERIDEPGLRSLRTARHLEPGMVLTVEPGIYFIDHLLDQALAD-PAQACFFNQEVLQRFRNFGGVRIEEDVVVTDSGMELLTCVPRTVEEIEACMAGCDKALAP-SGPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q11136-1", "uniprot_id": "PEPD_MOUSE", "id": "Q11136-1", "name": "Xaa-Pro dipeptidase", "aln": "MASTVRPSFSLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--GAVQAASAVVLQGGEEMQRYCTDTSIIFRQESFFHWAFGVVESGCYGVIDVDTG----KSTLFVPRLPDSYATWMGKIHSKEYFKEKYAVDDVQYTDEIASVLTSRNPSVLLTLRGVNTDSGSVCREASFEGISKFNVNNTILHPEIVECRVFKTDMELEVLRYTNRISSEAHREVMKAVKVGMKEYEMESLFQHYCYSRGGMRHTSYTCICCSGENAAVLHYGHAGAPNDRTIKDGDICLFDMGGEYYCFASDITCSFPANGKFTEDQKAIYEAVLRSCRTVMSTMKPGVWWPDMHRLADRIHLEELARIGLLSG--SVDAMLQVHLGAVFMPHGLGHFLGLDVHDVGGY-PEGVERIDEPGLRSLRTARHLEPGMVLTVEPGIYFIDHLLDQALAD-PAQACFFNQEVLQRFRNFGGVRIEEDVVVTDSGMELLTCVPRTVEEIEACMAGCDKASVPFSGQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12955-1", "uniprot_id": "PEPD_HUMAN", "id": "P12955-1", "name": "Xaa-Pro dipeptidase", "aln": "MAAATGPSFWLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--PAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTG----KSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSG--SVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGY-PEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALAD-PARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG79-1", "uniprot_id": "Q9VG79_DROME", "id": "Q9VG79-1", "name": "Xaa-Pro dipeptidase", "aln": "-----MAAFQMG-SGYAVPMTLFRNNRDRAGKA----------------------------------------------ILKELLPGL--KFNDGNLLVLLEGGKDQSLYNTDVDYVFRQESYFQYLFGVKEPGCYGILTIDVKTGAQKSVLFVPRFPDEYGTWMGELLGLQEFKAMYEVDEVFYVDEMSVYLEGASPKLILTLSGTNSDSGLTLQPPDFAGKEKYVTDCNLLYPILSECRVIKSPEEIEVLRYVAKVSSDAHIKVMRFMRPGRMEFEGESLFLHHAYSVGGCRHASYTCICGSGTNSSILHYGHAGAPNSKPVQDGDLCLFDMGANYCGYAADITCTFPANGKFTDDQKFIYNAVLDARNAVTESARDGVSWVDMHKLAGRVLLQRLKEGGMLKG--DVEEMLEAGVSGVFQPHGLGHLIGLDVHDVGGYLPKEPKRPSEPWLSKLRFARILKAGMYVTIEPGCYFINWLMDRALAD-PNIAKFINAEMFNRFRNFGGVRIEDDVLITKTGVENFAIVPRTVEDIEATMT-CKYDSPV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43590-1", "uniprot_id": "YFH6_YEAST", "id": "P43590-1", "name": "Uncharacterized peptidase YFR006W", "aln": "MCLEPISLVVFGSLVFFFGLVKYFKRGERQRTRGILQPEYKDKYYYSKEKGEEMGEVANVNEIPVKIRNHKYPAKEHNLRVKDLLLNRNPKLSKISTAFFIAGEELEGNKYCDTNKDFRQNRYFYHLSGVDIPASAILFNCSTD----KLTLFLPNIDEEDVIWSGMPLSLDEAMRVFDIDEALYISDLGKKFKELQDFAIFTTDLDNVHDENIAR--------SLIPSDPNFFYAMDETRAIKDWYEIESIRKACQISDKSHLAVMSALPIELNELQIQAEFEYHATRQGGR-SLGYDPICCSGPACGTLHY----VKNSEDIKGKHSILIDAGAEWRQYTSDITRCFPTSGKFTAEHREVYETVLDMQNQAMERIKPGAKWDDLHALTHKVLIKHFLSMGIFKKEFSEDEIFKRRASCAFYPHGLGHMLGLDVHDVGGN---PNYDDPDPMFRYLRIRRPLKENMVITNEPGCYFNQFLIKEFLEKHPERLEVVDMSVLKRYMYVGGVRIEDDILVTKDGYENLTGITSDPDEIEKIVQKGLKKPRSGFHVIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* . :. : . :* : : * . ..: * : *.. ***: :* ** ... :: .. * .**:*.: . * * . : : :*:. * .::. : . ::* * .. : . . :. : * *.:* *:* :* . ::*..:* ** : * : :: * ::. ** .* ** ** .. *** . *.. ::. . *:* *.:: :::*** **:.**** ::: :*::** . . : *. * *:* *: :: ::.: *::. . : :.: . .* ******::*:******* :* : ** * *: .* :* *** ** : *:.. * . * ..: .:::*: .******:*:::*. * * :: :. ::** : ", "identical_positions": 108, "similar_positions": 152, "identity": "19.46%" }, { "cls_id": "homologset.agr.SGD:S000001905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K268-1", "uniprot_id": "ABCF3_MOUSE", "id": "Q8K268-1", "name": "ATP-binding cassette sub-family F member 3", "aln": "MATCADILRSEFPEIDGQVFDYVTGVLHSGS-ADFESVDD-------LVEAVGELLQEVSG-DSKDDAGIRAVCQRMYNTLRLAEPQNQ--GNSQVLLDAPIQLSKIMENYDCDTKLPGLLK--------REQSSTVNAKKLEKAEARLKAKQEKRSEK-ETLKTSNPLVLEEASASQAGSRKESRLES-SGKNKSYDVRIENFDVSFGD-RVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISLLHVEQEVAGDDTPALQSVLESDTVREDLLRQERELSLRIAAG------------------RAEGSEAAQLAEIYGKLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRG-DFETFIKSKQERLLNQQREYEAQQQYRQHIQVFIDRFRYNANRASQVQSKLKMLEKLPELKPVDKESEVVLKFPDGFEKFSPPILQLDEVDFYYDPKH--SIFSRLSVSADLESRICVVGENGAGKSTMLKLLMGDLSPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPGLPEEEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRGGVILVSHDERFIRLVCKELWVCENGSVTRVEGGFDQYRALLQEQFRREGFL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H39-1", "uniprot_id": "ABCF3_RAT", "id": "Q66H39-1", "name": "ATP-binding cassette sub-family F member 3", "aln": "MATCADILRSEFPEIDGQVFDYVTGVLHSGS-ADFESVDD-------LVEAVGELLQEVSG-DSKDDAGIRAVCQRMYNTLRLAEPQNQ--GNNQVLLDAPIQLSKIMENYDCDTKLPGLLK--------REQSSTVNAKKLEKAEARLKAKQEKRSEK-ETLKTSSPLVLEEASASQAGSRKESRLES-SGKNKSYDVRIENFDVSFGD-RVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISLLHVEQEVAGDDTPALQSVLESDTIREDLLRQERGLSLKIAAG------------------RAEGSEAALLAEVYTKLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRG-DFETFIKSKQERLLNQQREYEAQQQYRQHIQVFIDRFRYNANRASQVQSKLKMLEKLPELKPVDKESEVVLKFPDGFEKFSPPILQLDEVDFYYDPKH--IIFSRLSVSADLESRICVVGENGAGKSTMLKLLMGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPGRPEEEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGHALNNFRGGVVLVSHDERFIRLVCKELWVCEKGSVTRVEGGFDQYRALLQEQFRREGFL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUQ8-1", "uniprot_id": "ABCF3_HUMAN", "id": "Q9NUQ8-1", "name": "ATP-binding cassette sub-family F member 3", "aln": "MATCAEILRSEFPEIDGQVFDYVTGVLHSGS-ADFESVDD-------LVEAVGELLQEVSG-DSKDDAGIRAVCQRMYNTLRLAEPQSQ--GNSQVLLDAPIQLSKITENYDCGTKLPGLLK--------REQSSTVNAKKLEKAEARLKAKQEKRSEK-DTLKTSNPLVLEEASASQAGSRKESRLES-SGKNKSYDVRIENFDVSFGD-RVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAG------------------RAEGSEAAELAEIYAKLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRG-DFETFIKSKQERLLNQQREYEAQQQYRQHIQVFIDRFRYNANRASQVQSKLKMLEKLPELKPVDKESEVVMKFPDGFEKFSPPILQLDEVDFYYDPKH--VIFSRLSVSADLESRICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPGRPEEEYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRREGFL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW13-1", "uniprot_id": "Q9VW13_DROME", "id": "Q9VW13-1", "name": "ATP-binding cassette sub-family F member 3", "aln": "MSEYTSILQREFPKIDHELLTYVVGVLTGSE-EDFESGDD-------IFEAVGDILQSVDC-DRSEES-VRTLCEQFLNIMKNNEVNVE--RKVLNAPVNIEEMAKNMERLDKDMQSIWVAN--------KDGANKVDSKKLGKAEAKLQQKQEKRQEVNKHGMIPVAVKLQTATASQVTNKKNTKLDQ-KGLNRSMDIKIENFDLAFGE-KVLLQNANLLLSYGRRYGLVGRNGLGKTTLLRMIAERQLQIPSHISVLHVEQEVVGDDTPAVESVLECDTERTRLLTREKEILAALNNG------------------VQDATLSNELSETYASLQNIEADKAVARASVILKGLGFDADMQLRPTKSFSGGWRMRLALARALFSKPDLLLLDEPTNMLDIKAIIWLENYLQTWATTILVVSHDRNFLDTVPTDIIHLHSQELEAYKG-NYEQFEKTKTEKLKSQRREYEAQMAHRAHVQDFIDRFRYNANRASSVQSKIKMLEKLPELKPVEKETVVTLKFPE-VEPLNPPVLAISEVTFRYNPEDPLPIFKGVNLSATSDSRICIVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQHHVDHLNMNVTCVGVLAELFPGRPDEEYRRQLGSFGISGPLALQSIASLSGGQKSRVALAKMCMAEPNFLVLDEPTNHLDIETIDALGRAINAFKGGVILVSHDERLIKVVCKELWVCGNRTVRAIEGGLDEYKREVYKEIEANS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43535-1", "uniprot_id": "GCN20_YEAST", "id": "P43535-1", "name": "Protein GCN20", "aln": "MASIGSQVRKAASSIDPIVTDYAVGYFNHLSGITFDAVQSKQVDLSTEVQFVSDLLIDAGASKAKVKELSESILKQLTTQLKENEAKLELTGDTSKRLLDINVLKSHNSKSDINVSLSMLGVNGDIEHTGRKMETRVDLKKLAKAEQKIAKKVAKRNNKFVKYEASKLINDQKEEDYDSFFLQINPLEFGSSAGKSKDIHIDTFDLYVGDGQRILSNAQLTLSFGHRYGLVGQNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKALQSVLDADVWRKQLLSEEAKINERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISDKLVDMESDKAEARAASILYGLGFSTEAQQQPTNSFSGGWRMRLSLARALFCQPDLLLLDEPSNMLDVPSIAYLAEYLKTYPNTVLTVSHDRAFLNEVATDIIYQHNERLDYYRGQDFDTFYTTKEERRKNAQREYDNQMVYRKHLQEFIDKYRYNAAKSQEAQSRIKKLEKLPVLEPPEQDKTIDFKFPE-CDKLSPPIIQLQDVSFGYDENN--LLLKDVNLDVQMDSRIALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDSMDLTTSAVDWMSKSFPGKTDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCLNNPHILVLDEPSNHLDTTGLDALVEALKNFNGGVLMVSHDISVIDSVCKEIWVSEQGTVKRFEGTIYDYRDYILQSADAAGVVKKH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . :: ..** : *..* : . *:: :. .: *.::* ... . . . .:: ::: . :: * : : . : . .. * . . : :. . *: *** *** :: * **.: . : : : : . *: .. .:* *::*:.**: .*: : :* .*:: *::*:******:**:**:***: :: *.*.:* *:*:******: **** *::***:.* * ** .* : : * : .* ::*:*** ***: ** **** .. * :**..*********:******.:*********:****: :* :* :**:*:..*:*.***** **: :.****: *.:.*: *:* ::: * .:* *: . :***: * :* *:* ***::**** ::...**::* ***** *:* :::. : :***: : :.**:: :.:* * *: :. ::. :.:.. :***.:** **.**:*:**::: :* .::* : *:****:****: :::..:.* ::. *** .:****::** :**:* *.:: : **********:* : : *:: :****:**** ::** .*:: *.***::**** .* **:*:**. * .** : :*: : :. . ", "identical_positions": 249, "similar_positions": 243, "identity": "32.98%" }, { "cls_id": "homologset.agr.SGD:S000001906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMA1-1", "uniprot_id": "UBP14_MOUSE", "id": "Q9JMA1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 14", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKN-GMTVLMMGSADA-LPEEPSAKTVFVEDMT-EEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSGRETDSSSAPAVTPSKKKSLIDQYFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDLEDKK--------------------------VNQQPNANDKNSPP-KEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVRRKQDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EK08-1", "uniprot_id": "F7EK08_RAT", "id": "F7EK08-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKN-GMTVLMMGSADA-LPEEPSAKTVFVEDMT-EEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSARETESSSASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMISFRSKFKDLEDKK--------------------------VNQQPNANDKNSPP-KEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKEDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEDSEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54578-1", "uniprot_id": "UBP14_HUMAN", "id": "P54578-1", "name": "Ubiquitin carboxyl-terminal hydrolase 14", "aln": "--MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKN-GMTLLMMGSADA-LPEEPSAKTVFVEDMT-EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS-----AQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQG-QYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKK--------------------------VNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKZ8-1", "uniprot_id": "Q9VKZ8_DROME", "id": "Q9VKZ8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "--MPAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NLQIKD-GAVVLLLGSKES-VPEVPATPVKFIEDMN-EAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELRTALSTFS--NDGTDTMST-----AFSISSAMKSIFAQMEKG-TTVTPIVLLQALHRASPQFAQTGENG-TYRQQDANECWAEILKMLQQKLRPKNQEP---------SNTVQKRHSSFIDQFFGGTFEVKMSSEEDPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKK--------------------------MEVDVVKRNEPNEEKKDVKYEQFWFDDDLGSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGDV--WFKFDDDEVSAVATDEILRLSGGGDWHCAYVLLYAPRRLEKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43593-1", "uniprot_id": "UBP6_YEAST", "id": "P43593-1", "name": "Ubiquitin carboxyl-terminal hydrolase 6", "aln": "MSGETFEFNIRHSGKVYP-ITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPGSTVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQLFHSMSIVFG------------------------DKFSEDFRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMYKGFGL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...:: . : : : :.** . :*:: ** * . *** * *** ::. : . * .::::*: :: : . *: *:**: * : .** *:.*:*****:***:*.: * :*: : : :. : : : : :* .:: **:**: *: . ****: ..:* * ****:* : :::: :. : . :.: * *:..:. . :: . .*. :*.*.*. .::: .** ::*:: *:* :: * :**** :**:* *** :* . . ::*:*:.: **: :* :: *** : .*.:::.:*.:* : : :. . : : * : *.* . * * .*:**:* .*.**** :::: . * * **:**:** * :.* *:***: . * :*:* : ", "identical_positions": 117, "similar_positions": 162, "identity": "21.95%" }, { "cls_id": "homologset.agr.SGD:S000001910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK9-1", "uniprot_id": "KCC1B_MOUSE", "id": "Q9QYK9-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAAFD--RDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE----------------------------------------------------------------------------------EASRQCMTRHSHPG----------------------------------------------------------------LGTSQSPKW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70150-1", "uniprot_id": "KCC1B_RAT", "id": "O70150-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAALD--RDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE----------------------------------------------------------------------------------EASRQGMTRHSHPG----------------------------------------------------------------LGTSQSPKW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2M8-1", "uniprot_id": "KCC1B_HUMAN", "id": "Q6P2M8-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFD--RDILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGE----------------------------------------------------------------------------------GASEQGMARHSHSG----------------------------------------------------------------LRAGQPPKW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VB2-1", "uniprot_id": "KCC1G_MOUSE", "id": "Q91VB2-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCI-KKSPAF---RDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPAPEVSRPDSHDSSITEAP------------ILDPSTPLPALTRLPCSHSSRPSAPSGGRSLNCLVNGSLRISSSLVPMQQGP-LATGPCGCCS---------------------------------------------------SCLNIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTHCRGGQTGVCLVM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNJ7-1", "uniprot_id": "KCC1G_RAT", "id": "Q7TNJ7-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCI-KKSPAF---RDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPAPEVSRPGSHDSSITEAP------------ILDPSTPLPALTRLPCSHSSRPSAP-GGRSLNCLVNGSLRISSSLVPMQQGP-LATGPCGCCS---------------------------------------------------SCLNIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTHCRAGQTGVCLIM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NX5-1", "uniprot_id": "KCC1G_HUMAN", "id": "Q96NX5-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI-KKSPAF---RDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---IMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEITITEAP------------VLDHSVALPALTQLPCQHGRRPTAP-GGRSLNCLVNGSLHISSSLVPMHQGS-LAAGPCGCCS---------------------------------------------------SCLNIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSHCRAGQTGVCLIM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSZ5-1", "uniprot_id": "A0A8M9PSZ5_DANRE", "id": "A0A8M9PSZ5-1", "name": "", "aln": "-------------------------MSVSLRSAQFPLPSHVILCHCCPCLRLDSFCKRQKSCWSCYRPEEIPVEAHAEMGRKEGE--YEWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKTGKLFAMKCV-KKK-NK---RDINLENEIAVLRKIKHENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSVIRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETETR--------LFSKIMKGQY--EFDSPFWDDISDSAKDFIRNMMQKNPKMRFNTEQALRHPWIIGKTARS--QDIYHSVSEQMQKNFAKSKWKQAFNATVAINHMKKLQQAHSEACVRLKDSPR-----------------DVPEIK------------VIASSTPESVRKKLLSETP----EPNGSMNVPC---GSTEAKSQYHPMRVSH-SETTHVG-------------------------------------------------------TLTIAEKGKHVYHSEPADLNGYAKR-------------SSNRPGQNLQTGVCSVM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91YS8-1", "uniprot_id": "KCC1A_MOUSE", "id": "Q91YS8-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "------------------------------------------------------------------------------MPG--AVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE----------------------------------------------------------------------GQGQ-------TGSHGELLTPTAG---GPAAGCCCRD---------------------------------------------------CCVEPG--SELPPAPPPSSRAMD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63450-1", "uniprot_id": "KCC1A_RAT", "id": "Q63450-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "------------------------------------------------------------------------------MPG--AVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE----------------------------------------------------------------------GQGQ-------TASHGELLTPTAG---GPAAGCCCRD---------------------------------------------------CCVEPG--SELPPAPPPSSRAMD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14012-1", "uniprot_id": "KCC1A_HUMAN", "id": "Q14012-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "------------------------------------------------------------------------------MLG--AVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE----------------------------------------------------------------------GQGQ-------TASHGELLTPVAG---GPAAGCCCRD---------------------------------------------------CCVEPG--TELSPTLPHQL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1H0-1", "uniprot_id": "E7F1H0_DANRE", "id": "E7F1H0-1", "name": "", "aln": "------------------------------------------------------------------------------MPL--GEDGPSWKKKTANIKDIYDFKEVLGTGAFSEVMLAEEKRTRKLVAVKCIAKKALEG---KENSIENEIAVLHKIKHANIVSLEDIFESKSHLYLVMQLVSGGELFDRIVEKGFYTEKDASKLIQQILDAVKYLHDMGIVHRDLKPENLLYYSMDEESKIMISDFGLSKIEGSGS--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILRAEY--EFDSPYWDDISDSAKDFIVHLMEKDPNQRYTCEQALQHPWIAGDTALD--KNIHESVSAQIKKNFAKSKWKQAFNATAVVRHMRRLQLGTSQE----------------------------------------------------------------------GPPQNT---LPSPCHGHLLLPEGDEDDSVRENSGCSE---------------------------------------------------GVSDGNDIQNCSYHLHPTSRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IU85-1", "uniprot_id": "KCC1D_HUMAN", "id": "Q8IU85-1", "name": "Calcium/calmodulin-dependent protein kinase type 1D", "aln": "------------------------------------------------------------------------------MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKG---KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLD----------------------------------------------------------------------SSNASVSSSLSLASQKDCLAPSTLCS-FISSSSGVSG---------------------------------------------------VGAERRPRPTTVTAVHSGSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7URA4-1", "uniprot_id": "A0A8N7URA4_DANRE", "id": "A0A8N7URA4-1", "name": "", "aln": "------------------------------------------------------------------------------------MPLLRDLRKKDDINAVYELKEKLGEGSFSEVRVAQHRCTQKLVAVKCIRKRALKG---KESMLENEVAVLRRINHENIVSLEETFETPTKLYLVMTLLTGGELLNRILERGSYTEKDASRVIYQVLQAVKYLHQLGVVHRDLKPENLIFETPLEDSKIVISDFGLSKMEEQG---ALSTACGTPAYVAPELLQQKTYGKEVDLWAIGVITFILLCGYPPFYDDNDTQ--------LYKLIIKAEY--EFDSPYWNDISDSAKDFIVHLLQKDPAKRFNCEQASQHPWISGGAALD--RNIHGSVSAQIQKNFAKSHWKRAFNATIIVHHLTKKAHPGEDD---------------------------------------------------------------------------------EGNQSTSIGNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UHL1-1", "uniprot_id": "CAMKV_MOUSE", "id": "Q3UHL1-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAATQSA--SDAATPGAAGGAIAAAAAAAAAG------------------GAASASGASATAATEGGAGCAAKSDDIASADRSATPATDGSATPATDGSVTPATDGSITP------------------------------------------------ATDGSVTPATDRSATPATDGRATPATEESTVPATQSSALPAAKAAATPEPAVAQPDSTAL---------------EGATGQAPPSSKGEEATGCAQESQRVETS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63092-1", "uniprot_id": "CAMKV_RAT", "id": "Q63092-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVVKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAAT-----SDAATPGAAGG-----AVAAAAG------------------GAAPASGASATVGTGGDAGCAAKSDDMASADRSATPATDGSATPATDGSVTPATDGSITP------------------------------------------------ATDGSVTPATDRSATPATDGRATPATEESTVPAAQSSAAPAAKAAATPEPAVAQPDSTAL---------------EGATGQAPPSSKGEEATGCAQESQRVETS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCB2-1", "uniprot_id": "CAMKV_HUMAN", "id": "Q8NCB2-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSSTAAAQSASATDTATPGAAGG-----ATAAAAS------------------GATSAP--------EGDAARAAKSDNVAPADRSATPATDGSATPATDGSVTPATDGSITP------------------------------------------------ATDGSVTPATDRSATPATDGRATPATEESTVPTTQSSAMLATKAAATPEPAMAQPDSTAP---------------EGATGQAPPSSKGEEAAGYAQESQREEAS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY49-1", "uniprot_id": "CAMKV_DANRE", "id": "Q7SY49-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCLKPGEKKDYN-SPTEITDKYDLGQIVKSEEFCEIFRAKDKNTLKMYTCKKFLKKDGRK---VRKAAKNEIVILKMVKHPNILQLVDVYETRKEYYLFLELATGREVFDWILDQGYYSERDTSNVIRQVMEAVAYLHSLKIVHRNLKLENLVYYNRLKHSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWALGVIMYILLSGNPPFYDEADDDDYENHDKNLFRKILAGDY--EFDSPYWDEISDSAKNLVSRLMEVDQDQRLTAQEAINHEWISGNAASD--KNIKENVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPENQTAAAT---------------------APAAEAA------------------AASPSE-----------------ADPAAGAQETPQAASEASTAPSS---------------------------------------------------------------TAESLSASIEVPAVEPANAEAASAAVQP----------PAEPVVHVPEPEQPVPTS-------------------RCNGEASALDTVEEQSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JVK9-1", "uniprot_id": "A0AC58JVK9_DANRE", "id": "A0AC58JVK9-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "---------------------------------------------------------------------MMRAGAAMPFGCLTLGEKKDYN-SPSEVTDKYDLGQVVKSEEFCEIFRAKDKNTLKMYTCKKFLKKDGRK---VRKAAKNEILILKMVKHHNILQLVDVFETRKEYFLFLELATGREVFDWILDQGYYSERDTSNVIRQVLEAVAYLHSLRIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYDETDDDDYDNHDKNLFRKILSGDY--EFDSPYWDDISDSAKSLVACLMDVDQDQRLTAQEAINHEWISGNAASD--KNIKDGVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPDQSDSGAS---------------------SPALGAS------------------GGP--------------------------------------VTPST---------------------------------------------------------------TPVPLAATPEASASTRCNGEMLTSQQR-------------------------------------------------------SGDNREE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANJ4-1", "uniprot_id": "A0A8M3ANJ4_DANRE", "id": "A0A8M3ANJ4-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------MRVDAVMPFGCLALRDGRTYN-SLSDITDKYEIGQVLKAKEFCELCLVKERQTDKVYVCKKFLKKDGRK---VRKAAKNEIMILKMVKHPNILQLIDAFETRKEFFIIQELATGGDVFDWILDQGNYTERDAANVIRQVLEAVAYLHSLNIVHRNLKLENLMYYRESNHNKVVLRDFYLSRFENGS----ITEPCGTPEYLAPEVVARHRYGRPVDCWAVGVIMYILLSGNPPFYDETEEENTDMHNRIIFCRIVGGEF--EFDSPYWDDISPAAKELVCRFMEVDQMLRITAQDALTHEWIAGNGASE--KNLKEGVCAQFEKNFAKAKWRKAIRVTTFMQRLRATDIGSSDGAVEGQAEGVKADGLDGKGIQTDSGGVSAGSVSHEVSVESRPTENQEAGQTKVEEKETETVGQSNSSLKIQAEEPLNKKETTEGTSEIKDKPTTGANQKAASVQPIKTSDSRENSIPVEPEATTLGSVEKKSPFHDTPNRRKIAANLSMDHSSCSEAKTATLSTGNEPPLQSEDKKDTVHDMTASSWCQTQLPEAVAERSAEVGAPSEVNPKSKELKKGRADKGSQSVKNIQSVYAGLGSSSLGQDQTVFVQELQEMVHGASGYGSPYCPTYSVGQYGGLDPGSAASADWQMDCVIEQIEKQMAAVLEKIEGDMPSLLEQISDHPETLPRAKSASSSPSPRPRSYHHSTPPPLPTTPRPVMPSLPHLTIPPPSYPPPSPPSQIQGHSHPAPEESTSDGQKSTKRSGQSPRGSVSGKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91YA2-1", "uniprot_id": "KPSH1_MOUSE", "id": "Q91YA2-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKNDVYKHFITEVDSVGPLKAGFP---ATSQYAPPCPGVPNTGHTAPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRE------------------------------------------------------------------------------RELRELNLRYQQQYNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABY1-1", "uniprot_id": "D4ABY1_RAT", "id": "D4ABY1-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSATKNDVYKHFITEVDSVGPLKAGFP---ATSQYAPPCPGAPTTGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRE------------------------------------------------------------------------------RELRELNLRYQQQYNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11801-1", "uniprot_id": "KPSH1_HUMAN", "id": "P11801-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFP---AASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRE------------------------------------------------------------------------------RELRELNLRYQQQYNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q501V0-1", "uniprot_id": "KPSH1_DANRE", "id": "Q501V0-1", "name": "Serine/threonine-protein kinase H1 homolog", "aln": "MGCRTSKVLPEPPGDVQLDLVKKVEPH---QTDVYKNFIKYDG--GGEKTGSPSPQGQSQAVAKVSQSPPPANDQPEPADSHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREG---RE-VCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITHRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAVDMWALGVISYILLSGTMPFEDDNRMR--------LYRQILKGKY--SFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKHPWIVSMAASSSMKNLHRSISQNLLKRASSRCHSTKSSQSTRSSRSTKSSKARRLRE------------------------------------------------------------------------------KELRELNRRYQQQCNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08414-1", "uniprot_id": "KCC4_MOUSE", "id": "P08414-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCPSSPCSSVTAS----TENLVPDYWIDGSNRDP-LGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTSIQENHKASSDPPSTQDAKD------------------------------------------STDLLGKKMQEEDQEEDQVEAEASADEMRKLQSEEVEKDAGVKEEE---------------------------------------------------TSSMVPQDPEDELETDDPEMKR-DSEEKLKSVEEEMDPMTEEEAPDAGLGVP-QQDAIQPEY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13234-1", "uniprot_id": "KCC4_RAT", "id": "P13234-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCPSSPCSSVTSS----TENLVPDYWIDGSKRDP-LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKD------------------------------------------KTDPLENKMQAGDHEA----AKAAADETMKLQSEEVEEEEGVKEEEEEEEEE-------------------------------------------EETSRMVPQEPEDRLETDDQEMKR-NSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16566-1", "uniprot_id": "KCC4_HUMAN", "id": "Q16566-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDA-LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQDGNED----------------------------------------MKAIPEGEKIQGDGAQA---AVKGAQAELMKVQALEKVKGADINAEE---------------------------------------------------APKMVPKAVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVP-QQDVILPEY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRA7-1", "uniprot_id": "A0A8M1RRA7_DANRE", "id": "A0A8M1RRA7-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "-----------------------------------------------------------MPTSRSDARP--------------VEYWVDGSRRDATVEDFYNMGPELGRGATSVVLRCEEKQTEKPYAVKVLKKTI------DKKIVRTEIGVLLRLSHPNIIRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVHRDLKPENLLYADLSIDAPLKIADFGLSKIIDEQV--TMKTVCGTPGYCAPEILRGNAYGPEVDMWSVGVILYILLCGFEPFFDQRGDQ-------YMYSRILNCDY--EFVSPWWDEVSLNAKDLVNKLIVLDPHKRLTVKQALEHPWVLGKAARF---SHMDTTQRKLQEFNARRKLKAAMKAVVATSRMHEGSRRRTDSCEMP--NTDKTSCQ----------------------------------------------------SSIQKENTTN-----SSREPISMKEGSEQVADGALGPSSS---------------------------------------------------TPQTTPKSKPFTQSGPVPTRPPLIAEGHRQTSVIPKAPVVRPREPKKSFSVEPGGKHEVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27466-1", "uniprot_id": "KCC1_YEAST", "id": "P27466-1", "name": "Calcium/calmodulin-dependent protein kinase I", "aln": "----------------------------------------------------------------MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEE-LLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQD--------FLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKT--HNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESD-----------------------------------------------------------------------SDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSK-------------------------------------------------LKSELTSKAFAQLVNTVLAEKEKFLNINRVCSSDSDLPGSDIKSLDEAKEKPEGKDTKTEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :. : . . * . . *: :* : * *:: : : . : . : * .* :::: *: :* ::* *: : :: .* *:* :.**:** ***:: . : : ** :: : .*: * ***:: : * *::*:* : **.* .* : : : : * .:* **.:: : : * . . . *: : : ", "identical_positions": 42, "similar_positions": 76, "identity": "4.99%" }, { "cls_id": "homologset.agr.SGD:S000001911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1E4-1", "uniprot_id": "GYS1_MOUSE", "id": "Q9Z1E4-1", "name": "Glycogen [starch] synthase, muscle", "aln": "------------------MPLSRSLS-VSSLPGLEDWEDE---FDPENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYYLVGPYTEQGVRTQVELLEPPT--------PELKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFL--------AQNEEKPYVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAG-AVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVG-------SLP-DMNKMLDKEDFTMMKRAIFATQRQS--FPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSA--YGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALAKAFPDHFTYEP---------HEVDATQGYRYPRPASVPPSPSLSRHSSPHQSEDEEEPRDGPLGEDSERYDEEEEAAKDRRNIRAPEWPRRASCSSSTGGSKRSNSVDTGPSSSLSTPTEPLSPTSSLGEERN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RRU1-1", "uniprot_id": "GYS1_RAT", "id": "A2RRU1-1", "name": "Glycogen [starch] synthase, muscle", "aln": "------------------MPLSRSLS-MSSLPGLEDWEDE---FDPENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYYLVGPYTEQGVRTQVELLEPPT--------PELKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFL--------AQNEEKPYVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAG-AVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADIFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVG-------SLP-DMNKMLDKEDFTMMKRAIFATQRQS--FPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSA--YGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALAKAFPDHFTYEP---------HEVDATQGYRYPRPASVPPSPSLSRHSSPHQSEDEEEPRDGPLREDSERYDEEEEAAKDRRNIRAPEWPRRASCSSSTGGSKRSNSVDTGPSSSLSTPTEPLSPTSSLGEERN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13807-1", "uniprot_id": "GYS1_HUMAN", "id": "P13807-1", "name": "Glycogen [starch] synthase, muscle", "aln": "------------------MPLNRTLS-MSSLPGLEDWEDE---FDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLVGPYTEQGVRTQVELLEAPT--------PALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFL--------AQSEEKPHVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAG-AVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVG-------SLP-DMNKMLDKEDFTMMKRAIFATQRQS--FPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSA--YGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEP---------NEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKR-NSVDTATSSSLSTPSEPLSPTSSLGEERN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCB3-1", "uniprot_id": "GYS2_MOUSE", "id": "Q8VCB3-1", "name": "Glycogen [starch] synthase, liver", "aln": "------------------MLRGRSLS-VTSLGGLPVWEAER--LPVEDLLLFEVSWEVTNKVGGICTVIQTKAKTTADEWGENYFLIGPYFEHNMKTQVEQCEPTN--------DAVRKAVDAMNKHGCQVHFGRWLIEGSPYVVLFDISSSAWNLDRWKGDFWEACGVGIPHHDREANDMLIFGSLTAWFLKEVT--------DHADGK-HVIAQFHEWQAGTGLILSRARKLPIATVFTTHATLLGRYLCAA-NIDFYNQLDKFDIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSNVTVVVFFIMPAKTNNFNVETLKGQAVRKQLWDTVHCLKEKFGKKLYDGLLRG-------EIP-DMNSILDRDDLTIMKRAIFSTQRQS--LPPVTTHNMIDDSTDPILSTIRRIGLFNNRADRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFVQEHVADPTA--YGIYIVDRRFRSPDDSCNQLTQFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKFHLEP---------TSPPTTDGFKYPRPSSVPPSPSGSQASSPQCSDAEDE------EDEDERYDEEEEAERDRLNIKSP----------------------------FSLNHFPKGKKKLHGEYKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17625-1", "uniprot_id": "GYS2_RAT", "id": "P17625-1", "name": "Glycogen [starch] synthase, liver", "aln": "------------------MLRGRSLS-VTSLGGLPAWEAER--LPVEDLLLFEVSWEVTNKVGGICTVIQSKAKTTANEWGENYFLIGPYFEHNVKTQVEPCEPAN--------DAVRKAVDAMNKHGCQVHFGRWLIEGSPYVVLFDISSSVWNLDRWKGDFWEACGVGIPHDDREANDMLIFGSLTAWFLKEVT--------DHADGK-HVIAQFHEWQAGTGLILSRARKLPIATIFTTHATLLGRYLCAA-NIDFYNQLDKFNIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEADHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHATYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSNVTVVVFFIMPAKTNNFNVETLKGQAVRKQLWDTVHCMKEKFGKKLYDGLLRG-------EIP-DMNSILDRDDLTIMKRAIFSTQRHS--LPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTA--YGIYIVDRRFRSPDDSCNQLTQFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKFHLEP---------TSPPTTDGFKYPRPSSVPPSPSGSQTSSPQSSDVENE------GDEDERYDEEEEAERDRLNIKSP----------------------------FSLNHIPKGKKKLHGEYKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54840-1", "uniprot_id": "GYS2_HUMAN", "id": "P54840-1", "name": "Glycogen [starch] synthase, liver", "aln": "------------------MLRGRSLS-VTSLGGLPQWEVEE--LPVEELLLFEVAWEVTNKVGGIYTVIQTKAKTTADEWGENYFLIGPYFEHNMKTQVEQCEPVN--------DAVRRAVDAMNKHGCQVHFGRWLIEGSPYVVLFDIGYSAWNLDRWKGDLWEACSVGIPYHDREANDMLIFGSLTAWFLKEVT--------DHADGK-YVVAQFHEWQAGIGLILSRARKLPIATIFTTHATLLGRYLCAA-NIDFYNHLDKFNIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSDITVMVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRG-------EIP-DLNDILDRDDLTIMKRAIFSTQRQS--LPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTA--YGIYIVDRRFRSPDDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKFHVEL---------TSPPTTEGFKYPRPSSVPPSPSGSQASSPQSSDVEDE------VE-DERYDEEEEAERDRLNIKSP----------------------------FSLSHVPHGKKKLHGEYKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFC8-1", "uniprot_id": "GYS_DROME", "id": "Q9VFC8-1", "name": "Glycogen [starch] synthase", "aln": "MRRQQSYRFEDNESTSYALRMNRRFSRVESGADLKDYFDRGDIASRENRWNFEVAWEVANKVGGIYTVIRSKAYVSTEEMGEQLCMMGPYKEHCARTEMEEMEFPRG-------NPLLDAVNSLRSRGYKIHTGRWLVDGNPQLILFDIGSAAWKLDQFKSEMWEKCHIGIPHLDIETNDAIILGFMIAEFLEEFRNFAVTYSQNNELSAPRIVAHFHEWQAGVGLIVLRTRLVEIATVFTTHATLLGRYLCAG-NTDFYNNLDKFAVDEEAGKRQIYHRYCLERGATHLAHVFTTVSEITGYEAEHLLKRKPDIITPNGLNVKKFSAIHEFQNLHAVAKEKINEFVRGHFYGHIDFDLDKTLYFFIAGRYEFGNKGADIFIEALARLNAMLKHEKPDTTVVAFLIFPTKTNNFNVDSLRGHAVIKQLRDTINNVQQAVGKRMFDTCLQG-------NIP-NADDLLQKDDLVKIKRCMFAMQRDS--MPPVTTHNVADDWNDPVLSSIRRCHLFNSRHDRVKMVFHPEFLTSTNPLFGIDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEEHISDPKS--YGIYIVDRRYIGLENSVQQLSSFMMEFSRLNRRQRIIQRNRTERLSDLLDWRTLGIYYRQARVKALQAVYPD-YVDEL---------SLYGSKNNLIFSRPHSEPPSPTSSRHTTPAPSVHGSD----------DEDSVDEETELKELGIK-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23337-1", "uniprot_id": "GYS1_YEAST", "id": "P23337-1", "name": "Glycogen [starch] synthase isoform 1", "aln": "--------------------MARDLQ---------------------NHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEKLDWEDESIFPEELLPIQKTLMSMREKGVNFVYGNWLIEGAPRVILFELDSVRHFLNEWKADLWSLVGIPSPEHDHETNDAILLGYVVVWFLGEVS---------KLDSSHAIIGHFHEWLAGVALPLCRKKRIDVVTIFTTHATLLGRYLCAAGDVDFYNNLQYFDVDQEAGKRGIYHRYCIERAAAHTADVFTTVSQITALEAEHLLKRKPDGILPNGLNVVKFQAVHEFQNLHALKKDKINDFVRGHFHGCFDFDLDNTVYFFIAGRYEYKNKGADMFIESLARLNYRLKVSGSKKTVVAFLIMPAKTNSFTVEALKSQAIVKSLENTVNEVTASIGKRIFEHTMRYPHNGLESELPTNLDELLKSSEKVLLKKRVLALRRPYGELPPVVTHNMCDDANDPILNQIRHVRLFNDSSDRVKVIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETDQAKDYGIYIVDRRFKSPDESVEQLADYMEEFVNKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLGLRRAYPEQFKQLVGETISDANMNTLAGGKKFKIARPLSVPGSPKVRSNSTVYMTPGDLG------------TLQDANNADDYFNLSTNG----------------------------AIDNDDDDNDTSAYYEDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : ***: **:*:**** :*:::** .: : *:: ::** : .:::* : : :: ::..:* :. *.**::* * ::*:::. *:.:*.::*. : * * *:** :::* : . ** *. : ::.:**** ** .* : * : : :.*:**************. ****:*: * :*:***:* ******:**.:.* *.******:**. **:*:****** : ****** **.*:******** * :*::******:* :**:*::*:::*******: *****:*:*:*:*** *: .. **:.*:*:*::**.*.*::*:.:*: *.* :. : : .*::::: : .:* : :.:*. .: . :*: ::: :* :*** ***: ** .**:*. **: ***. ****:::*****.:..*:: :**:*****************************:**::**:****.:::: : : *****:***: . ::* .**:.:: * . .***** **************: :* * ** * .:*: : . .** * * **. :: : : : . .: ", "identical_positions": 273, "similar_positions": 206, "identity": "34.21%" }, { "cls_id": "homologset.agr.SGD:S000001914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86PD7-1", "uniprot_id": "QPCT2_DROME", "id": "Q86PD7-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "---------------------MRLLLRNYSLMEAVKRLLPRPRKKIYNLGACFELVDIPKISYNP---------SELSEPRFLEYSNLSDKLHLR-EAIDKILIPRVVGTTNHSIVREYIVQSLR-DLD--WDVEVNSFHDHAPIKGKLHFHNIIATLNPNAERYLVLSCHYDSKYMP----GVEFLGATDSAVPCAMLLNLAQVLQEQLKPLK--------------KSKLSLMLLFFDGEEAFEEWGPKDS-IYGARHLAKKWHHE----------GKLDRIDMLVLLDLLGA--PDPAFYSFFENTESWYMRIQSVETRLAKLQ--------LLERYASSGVAQRDPTRYFQSQAMRSSFIEDDHIPFLRRNVPILHLIPVPFPSVWHTPDDNASVIDYATTDNLALIIRLFALEYLLAGTEAK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTH7-1", "uniprot_id": "Q9VTH7_DROME", "id": "Q9VTH7-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "---------------------MPCWRSFIALICLAIIVVVITICQSFHT-NFLTVGRNGTLRYEP---------TELNLGQMRMIAGLSDPENLR-KNVQRIAIKRAVSTPGHSEVRNYIVDYLK-KLN--WNVELDIFTQKVPIMSNVTFHNIVARQNPQTQRYLMFGCHYDSKYFK----DFDFMAATDSAVPCALMLNMATILKHQFH-----------------RSQVSLMLVFFDGEEAFGEWSQEDS-PYGSRHLAELWEKH----------GFLDKIDLFVLPDLIGA--KDVVFKKNILDTSGWFHRLVQLELKLFQAG--------IVR-------SER-PLFKFEPGID----VDDDHLPFTRRNVPVIHLISNKYPAVWHQAEDVEMNVDYNTTEQVGLVLRMFVMEYLNSAPSISNTLK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4AC85-1", "uniprot_id": "D4AC85_RAT", "id": "D4AC85-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------MAGGEDRRVVGTRHLLLL-ATILSLTAGILSPVSAVAWTQEKNYHQP---------AHLNSSSLRQVAEATSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQ-RLQAEWVVEVDTFLSRTPYG-YRSFSNIISTLNPEAKRHLVLACHYDSKYFP-QWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKD---------VSGSRPDLSLRLIFFDGEEAFLHWSPQDS-LYGSRHLAQKMASSPH-PPGSRGTNQLDGMDLLVLLDLIGA--ANPTFPNFFPKTTRWFTRLQAIEQQLSELG--------LLK-------DHSLERKYFQNFGY-GNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHSSTIDNLNKIIQVFVLEYLHL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYK2-1", "uniprot_id": "QPCT_MOUSE", "id": "Q9CYK2-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------MAGSEDKRVVGTLHLLLLQATVLSLTAGNLSLVSA-AWTQEKNHHQP---------AHLNSSSLQQVAEGTSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQ-RLQAEWVVEVDTFLSRTPYG-YRSFSNIISTLNPEAKRHLVLACHYDSKYFP-RWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKD---------VSGSKPDLSLRLIFFDGEEAFHHWSPQDS-LYGSRHLAQKMASSPH-PPGSRGTNQLDGMDLLVLLDLIGA--ANPTFPNFFPKTTRWFNRLQAIEKELYELG--------LLK-------DHSLERKYFQNFGY-GNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHASTIDNLNKIIQVFVLEYLHL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16769-1", "uniprot_id": "QPCT_HUMAN", "id": "Q16769-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------MAGGRHRRVVGTLHLLLLVAALPWASRGVSP--SASAWPEEKNYHQP---------AILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQ-RLQADWVLEIDTFLSQTPYG-YRSFSNIISTLNPTAKRHLVLACHYDSKYFS-HWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKT---------VSDSKPDLSLQLIFFDGEEAFLHWSPQDS-LYGSRHLAAKMASTPH-PPGARGTSQLHGMDLLVLLDLIGA--PNPTFPNFFPNSARWFERLQAIEHELHELG--------LLK-------DHSLEGRYFQNYSY-GGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK24-1", "uniprot_id": "A0A8M3AK24_DANRE", "id": "A0A8M3AK24-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------MA-----EMSFSSRLLALIGILTTLTS-----CDTIPWQEKKLKHEA---------TTLNSSELSSIVAHTDLDRMWQKDLKSMLVVRYPGSAGSQQVQQHIKSTLS-LLKAGWDVTEDSFYANTPYG-QLPFTNIIATLNPTAKRQLVLACHYDSKYYPPQWDGREFLGAIDSAVPCSMILELSRAQDDELKTLK------------NSGSDLSLQLLFFDGEEALYQWTSEDS-LYGSRHLAHKMATASH-PPEATNTSQLDSIDLFVLLDLIGG--PNPRFGNQFSSTTRWLSRLRNIERRLHALG--------QLE-------NHPNEVQYFWPGLH-VGLILDDHIPFLNRGVRILHLISTPFPAVWHTFDDNEENLDQTSISNLNKILQVFVLEYLNKKSPENQVVEGS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B5DFI7-1", "uniprot_id": "B5DFI7_RAT", "id": "B5DFI7-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MSPASRGRSRQRLGDRGLMKPPSLSKRRLLPRVQLLPLLLLALALGLAFYIVWNSWHPGVEEVSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPLLIVRPPGSPGNLQVRKFLEATLQ-SLSAGWHVELDPFTASTPLG-PLDFGNVVATLDPGAARHLTLACHYDSKFFP--PGLPPFVGATDSAVPCALLLELVQALDVMLSRIK------------QQAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQIMESIPH-SP---GPTRIQAIELFVLLDLLGA--PSPIFFSHFPRTARWFQRLRSIEKRLHRLN--------LLQ-------SHPQEVMYFQPGEP-PGPVEDDHIPFLRRGVPVLHLIAMPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH73-1", "uniprot_id": "QPCTL_MOUSE", "id": "Q8BH73-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MSPGSRGRPRQRLEDRGLMKPPSLSKRRLLPRVQFLPLLLLALAMGLAFYIVWNSWHPGVEEMSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPLLIVRPPGSSGNLQVRKFLEATLQ-SLSAGWHVELDPFTASTPLG-PLDFGNVVATLDPGAARHLTLACHYDSKFFP--PGLPPFVGATDSAVPCALLLELVQALDAMLSRIK------------QQAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQIMESIPH-SP---GPTRIQAIELFVLLDLLGA--SSPIFFSHFPRTARWFQRLRSIEKRLHRLN--------LLQ-------SHPQEVMYFQPGEP-PGPVEDDHIPFLRRGVPVLHLIATPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXS2-1", "uniprot_id": "QPCTL_HUMAN", "id": "Q9NXS2-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLP-LLLALAVGSAFYTIWSGWHRRTEELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLR-SLTAGWHVELDPFTASTPLG-PVDFGNVVATLDPRAARHLTLACHYDSKLFP--PGSTPFVGATDSAVPCALLLELAQALDLELSRAK------------KQAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQLMESIPH-SP---GPTRIQAIELFMLLDLLGA--PNPTFYSHFPRTVRWFHRLRSIEKRLHRLN--------LLQ-------SHPQEVMYFQPGEP-FGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43599-1", "uniprot_id": "YFI8_YEAST", "id": "P43599-1", "name": "Uncharacterized protein YFR018C", "aln": "---------------------------MGMKYVLPLRLIGLAYLLVLFQVHRVTGWELSYEQYHA---------AHLN----EAINPDSGWNKSTKNLLLPFNRTRVPGSEGSREIQRFIIEHFNNTLAGEWAVETQAFEEN-----GYRFNNLVMTLQNNASEYLVLAAHYDTKIAP-----TGMVGAIDSAASCAALLYTAQFLTHIACHERTKEYNDLESNTVVSNSTLGVKIVFFDGEEAIEEWGPEDS-IYGARRLAAQWLAD----------GTMTRIRLLFLLDLLGSGEEEPLVPSYYAETHQEYQLLNRIEDDLLFRRGDEINGESALAAEVARQRKHLDPTDYRFLGLG-HSVIGDDHTPFLAAGVPVLHAIPLPFPSTWHTVDDDFRHLDAAETRHWALLVCEFVVQSLRSRNQ-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VRQ9-1", "uniprot_id": "QPCT1_DROME", "id": "Q9VRQ9-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "---------------------MAIGSVVFAAAGLLLLLLPPSHQQATAG-NIGSQWRDDEVHFNR--------------------------------TLDSILVPRVVGSRGHQQVREYLVQSLN---GLGFQTEVDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFP---NDPGFVGATDSAVPCAILLNTAKTLGAYLQKEFR------------NRSDVGLMLIFFDGEEAFKEWTDADS-VYGSKHLAAKLASKRSGSQAQLAPRNIDRIEVLVLLDLIGA--RNPKFSSFYENTDGLHSSLVQIEKSLRTAG--------QLE----------GNNNMFLSRVS-GGLVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYLKRHTSPVNLRFYRT--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8I936-1", "uniprot_id": "Q8I936_DROME", "id": "Q8I936-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "------------------------MLGRIALFLTIIYVVFKAMFLRWVIEKPPFKFDDDEEHFNA--------------------------------TLAKLLKPRSVGSKGHAEVQDFIETELK---------RLDFITLKNDFQQGVNITNLVGFWNMRAKFYLMLTCHYDSKKPE-NVTTDEFLAAAEGAVSCAILLNVAKTLRQFLIDRWS------------EKKSVGLAFIFFDGHNSLSSDPYDENELLGATHFIDEEFIP------------LRDMAVAVTLSYIGA--PNQTFLSFFEVTNDLHNLIADIEQDLRKSG------------------ELDDCHVLFQKKTHYDKDLLDDHIVFDEQDVPVIHVSPHEFPNVLYTPADNVENLHYPTIRNMIKIIRCFVHDFYEKWQYFMKWRQAFAINYDFYDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .: . : .: : : : : *:: : : * : .***:* ::.* :.*..*: :* : : ::*:**.::: :. *: :: : : : . . :*. . . . : : :* * : *** * .* ::* . :* . : * :. : :. * : ", "identical_positions": 27, "similar_positions": 69, "identity": "6.11%" }, { "cls_id": "homologset.agr.SGD:S000001915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYT8-1", "uniprot_id": "D3ZYT8_RAT", "id": "D3ZYT8-1", "name": "1-phosphatidylinositol 3-phosphate 5-kinase", "aln": "MATDDKSSP------TLDSANDLPHSPASPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERG-------------EGGQ--GEQQSPSSSWSSPQIPSRTQSVRSPVPYKKQLN-------EELHRRSSVLAENILPNPQESTDSRRKAEPACGGHDPRTAVQLRSLSTVLKRLKEIMEGKS------------------------------------------QDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTD-----SNSIGEDLNALSDSTCSVSILDPSEPRTPVGSRKASRNIFLEDDLAWQS-------LIHPDSSSSALSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRNYIRTETT---EDERKILLDSAQLKDLWKKICHHTSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR------TSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK------------------EYLVSDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENE-------------------------------------------------------------------EKQAMERLLSANHNHMMALLQQLLQNESLS--SSWRDIIVSLVCQVVQTVRPDVKHQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVVSMDQLLTKPHLGTCHKFYMQLFQLPNEQTKTLMFFEGCAQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLTQSPSFHFLAEG---RGEEGASQEQ-----------------VSGSSLPQDPECPFDALSSDDSTLLESRTVPEKGELDNKSVPQAVASLKHQDYTTPTCPAGIPCALFALVPESLLPLHMD-QQDAVGD-----EQPETSQQTVEQQDPKS------QMRAFRDPLQDDTGMYVTEEVTSSEDKRKTYSLTFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFPEQIYWSPLLNKEVKEMESRRKKQLLRDLSGLQS--MNGNVQTK-SIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQ-SKHLDPFVHSKDTSCTSGSKSGNKTESDEERGLIPSDVLWPTKVDCLNPANHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRSSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGY----QHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRAN-------AEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLK-----------VSLLQDLKDFFQKVSQVYLAVDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKSWTEKMQARLMSSCVDTPQQLQSVLESLIAKKQSLCEALQAWNSRLQDLFQQEKGRKRPSVPPSPGRLRQ--GEESKISAMDTSPRNISPGLHNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEALAEQLVGGP--SDLDTASGSEDVFDGHLLGSTDSQVK-EKSTMKAIFANLLP-GNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKAT-LWNNAEEGLPTNSALDNRPKSSSPIRLPEVSGGQTNRTVEGEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGMESQGLEPQDEVDGGDTQKKQLTNPHVELQFSDANAKFYCRLYYAGEFHKMREVILGSSEED------FIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNN-TEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQ--GKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLDLNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T6-2", "uniprot_id": "FYV1_MOUSE", "id": "Q9Z1T6-2", "name": "1-phosphatidylinositol 3-phosphate 5-kinase", "aln": "MATDDKSSP------TLDSANDLPRSPASPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERG-------------EGGQ--GEQQSPSSSWASPQIPSRTQSVRSPVPYKKQLN-------EELHRRSSVL------------DSRRKAEPACGGHDPRTAVQLRSLSTVLKRLKEIMEGKS------------------------------------------QDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTD-----SNSIGEDLNALSDSTCSVSILDPSEPRTPVGSRKASRNIFLEDDLAWQS-------LIHPDSSNSALSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRNYIRTETT---EDERKILLDSAQLKDLWKKICHHTSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR------TSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK------------------EYLVSDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENE-------------------------------------------------------------------EKQAMERLLSANHNHMMALLQQLLQNESLS--SSWRDIIVSLVCQVVQTVRPDVKHQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVVSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQSPSFHLLTEG---RGEEGASQEQ-----------------VSGSSLPQDPECPREALSSEDSTLLESRTVLEKGELDNKSIPQAVASLKHQDYTTPTCPAGIPCALFALVPESLLPLHMD-QQDAVGN-----EQPETSQQTDEQQDPKS------QMKAFRDPLQDDTGMYVTEEVTSSEDQRKTYALTFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFPEQIYWSPLLNKEVKEMESRRKKQLLRDLSGLQG--MNGSVQAK-SIQVLPSHELVSTRIAEHLGDSQTLGRMLADYRARGGRIQ-SKHLDPFVHSKDASCTSGGKSGNKTESDEERGLIPSDVIWPTKVDCLNPANHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRSSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGY----QHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRAN-------AEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLK-----------VSLLQDLKDFFQKVSQVYLAVDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWTEKMQARLMSSSVDTPQQLQSIFESLIAKKQSLCEVLQAWNSRLQDLFQQEKGRKRPSVPPSPGRLRQ--GEESKINAMDTSPRNISPGLHNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEALAEQVVGGP--TDLDSASGSEDVFDGHLLGSTDSQVK-EKSTMKAIFANLLP-GNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKAT-LRNSAEEGLPANSALDNRPKSSSPIRLPEISGGQTNRTVEAEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQAGKEGLESQGLEPQDEVDGGDTQKKQLTNPHVELQFSDANAKFYCRLYYAGEFHKMREVILGSSEEE------FIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNN-TEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQ--GKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLDLNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I7-1", "uniprot_id": "FYV1_HUMAN", "id": "Q9Y2I7-1", "name": "1-phosphatidylinositol 3-phosphate 5-kinase", "aln": "MATDDKTSP------TLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA-------------EGGQ--GEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLN-------EELQRRSSAL------------DTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKS------------------------------------------QDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTD-----SNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQS-------LIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETT---EDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR------TSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK------------------EYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENG-------------------------------------------------------------------EKQAMERLLSANHNHMMALLQQLLHSDSLS--SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEG---RGHEGAVQEQ-----------------YGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHSTTACPAGLPCAFFAPVPESLLPLPVDDQQDALGS-----EQPETLQQTVVLQDPKS------QIRAFRDPLQDDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQG--MNGSIQAK-SIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQ-PKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSDAVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGY----QHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRAN-------AEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLK-----------VSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQ--GEESKISAMDASPRNISPGLQNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGP--PELDTASSSEDVFDGHLLGSTDSQVK-EKSTMKAIFANLLP-GNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKAT-QWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEED------FIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNN-TEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQ--GKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCH5-1", "uniprot_id": "A0A8M3BCH5_DANRE", "id": "A0A8M3BCH5-1", "name": "1-phosphatidylinositol 3-phosphate 5-kinase", "aln": "MAADDKASSSSS---VMDWSSEPPPSPTSPSHLTHFKPLTPEQDEPPLRSAYSSFVSLFRFNKEKTGANIAPAKKLAKLEEGRPPSVTEKSQSASSSPQGPRRNWSSPSHSIHGSETHRK----HPELLRRTSAAS-----------EGRRKSEAPLGSHDPRTAVQLR---TALKRLKEIMEGKS------------------------------------------QDSDLKQYWMPDSQCKECYDCNEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTD-----SSSIGEDLSALSDSPCSVCVLEPTEPRTPVGGRKASRNIFLEEDLAWQRKNSIGMRKNHQESQNSGLNSRLTVVQEDIGKSPARKRSASVTNLSLDRSGSSMVPAYESSVSPQNSRALPKTDHS---EEERKILLDSFQLKDIWKKICHNTTGMEFQDHRYWLRTYPNCIVGKELVNWLLRNGTISTRAQAIAIGQALVDGRWLDCVTHHDQIFRDEYALYRPLQSTEFSETPSPDSDSVNSLEGHSEPSWFKDIKFDDSDTEQLADENDYVTPSSSSPSKR------TSVSSFHSAVDSDSAASISLNMEQDNVNFHIKKQAKYPHVPPYPAEQKSMEPHDPFTPETDIHAPMEVLLSEDGGQHISISDAFIKESLFNRRVEEKAKEMLFTPLGWHHSSLDQLREENG-------------------------------------------------------------------EKKAMERLLSANHSHMMALLQQLLYSESLS--LSWRDIIVPVVRQVVQTVRPDVRSCDDDMDIRQFVHIKKIPGGKKFDSAVVNGFVCTKNIAHKKMNSYIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPNLVLVEKTVSRIAQDMLLEHGIAIVINVKPQVLDRVSRMTQGDLVISMDQLLTKPRLGTCHKFYLHSFQLPNSEVKTLMFFEGCPPQLGCTIKLRGASEYELARVKEIIIFMVCVAYHSQLEISFLMDEFAMPPSLAESSSFPCLLESTTLREEDETSGERESQDNDESTLGDDNLTLVPGDDFETGFTGTIKAHSREPSTSESSHKDGESPRINKNASITSFSGGEEENIKTSTPLSSFSSTFPQPVTPPFLISDVKEMSQEVVKGSGEGEKNKYLESTLVHQDSTSSETSLPPTRLFRDPLQDDTGLFVTEHVASSDDRLKSISALFKQELKDIILCISPFITFREPFLLTPAGLRCPSRDYFPEQVYLSPLLNKDSKELDGRRKRQLLKESSPGSGSLTNGSVSHQRAIQILPCHKLTSARIAEQVGSSQQLARMLADYRAQGGRIR-QREGTQFREAPPP------KAPIKADSEEDKGAGVIDMTWSTKLDCLNPINHQRLCVLFSSSSAQSNNAPNPCVSPWIVTMEFYGKNDLTLGVFLERYCFRPSYQCPSMYCETPMVHHIRRFVHGKGCVQIVLKELDSPVPGY----QHTILNYSWCRICKQVTPVVPLSNDSWSMSFAKYLELRFYGHQYTRRAN-------AEPCGHSIHKDYHQYFSYNQMVASFSYIPVRLLEICLPPPKIIIRNQGPSK-----------SSLQQDLKDFSQKVAQVYLAIDDRLTSLKTDTFSKTREEKMEDMFAQKDMEESELRGWIEKLQVRLQTSVIDSSQQLQAVLESVVVKKQGLCETLQSWNNRLQELFQQEKGRKRLSVPPSPGRHRQPTTDESKTSALESSPRNPSPVVPNGDKEDRHLNTFPS-SSGSSSLLQLPSPAEQPSDVITSGPSFPDQDSVSNPEDMFDGHLLGSNDSQVK-EKSTMKTILANLLP-GNSYNPIPFPFDPDKHYLMYEHERVPIAVCEREPSSIIAFALSCKEYKTALEELTKTT-AKTGGDDTSQTISAGESRVKNS----------------------PAKPS----------------------------DNSMSQLSRS------SVDADPLKEPESADKQKKQTGNPHIELQFSDANAKFYCRIYYAEEFHKMREEIMESTEDD------FVRSLSHCVNWQARGGKSGAVFYATEDDRFILKQMPRLEVQSFLDFAPHYFTYITGAVHLKRPTALAKILGVYRIGYKNSQNN-TEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDQGKESCEVVLLDENLLKLVHDNPLYIRSHCKAILRAAIHSDALFLSSHLIIDYSLLVGRDDSTDELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQ--GKMPTVVSPELYRTRFCEAMDKYFLMVPDHWSGLGLNC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96838-1", "uniprot_id": "FYV1_DROME", "id": "O96838-1", "name": "Putative 1-phosphatidylinositol 3-phosphate 5-kinase", "aln": "MTSNNQNNS------------SSHQHLHSPSKLTEFARNFEDKPESLFGRVVNKIQNVYNQSYNTVNDISSGSSSSSSTQPVQVVGKSQFFSDSQTSTAEIADVETSSQSSVRPQPPT-------TLSIRTNSETRGTSTSSNTAAEDSETSDRVETLPLPTSEANQGRTVSNVLKHISNIVATKNNNDLR-----------------------------------NYKDTELQRFWMPDSKAKECYDCSQKFSTFRRKHHCRLCGQIFCSKCCNQVVPGMIIRCDGDLKVCNYCSKIVLTFLKSS------SSEMGQDMQELQQHLS--------------------------------------------------------------------------NKLEVQDSGSSLAKHPQMQRAPLPRKTSVGYQEE---RFSSHPTYTTLSIDDRKNILQQSNS--LITLHEEMQRDLPAQNCGQRLIEFLNSNNKSANEVQAVAILNAMLAAGFLEPIVPDPEQMDFDSSLHYKFS------------------------------------------------KSSSSDTSR------TMSPQFEANPHAEPQPPKSMDQS----------------------------------------------------------------------AEEKEKELEN-----------ELENDRC-------------------------------------------------------------------YTTATSKLLASYCEHEEQLLAQMLRAHNLD--QEWDKVLQMLCSTAANHFKPEHCS-NDLMDIRNYVNFKKVPGGRRKDSKIVHGVAFSKNVAHKDMATHVPFPRILLLQCPIVYER-IEGKFVTIETVLLQEKEYLRNVCARIMSFKPNVVLVHKNVAGIAQDLLRSYEVTLVLDVKLSVMERLSRTLQCDIVSSIESNITMPKLGYCNDFYIRNYNG-----KTLMFFEKLTNPRGYTCLLRGGSNAELTRVKRVASALLFARYNWRLEMSFLLNEFAQPLSPKPS---------------------------------------------------IFDSKETSPKTETEAELRSKRPIILERKSEDKITTIVSENVSDFTDPLRASQAEALSTSP------------------------------------------------------------CAPPVVEALAVEPRYDNRFRTALSSTLLSVSPFLTFPLPYLETEQGRKCKLRKLFPAELYFSKQWSRTGLERPDSMGDGEAGKSEPGNK---------ENQMQLLPAHDFVLMKITAPAS-SRDIQSKLAEFRSFGGRLP-KGKAPMLRP--------------KKKNAEVIQRPQKVSEEQLYKDALDPQNHQRLPVLFCSFHYNPKGVSSFCKLPMLLDMKFYGQYDIMLEQFLQRYCCLFNSMCP--SCNLPMLGHVRRYVHSLGCVHVYLTEDLTRSD------PTRIYFTSWCSICNATTPTIPLSDAAKCLSLAKYLEMRFHGHAYKRRPPSTDAEQGGTVCEHSLHRDYVHHFSFRGVGAKFQYTPVEVWETDLPSLTVQLDLPQPFQS----------AQVQEEIKNFSIKGHEVYNRIHERIADLATEEENSPLVQHLKTMLTHDQFIFKQKIEIVHTLLTDNRATAYDTS-------DALAMARRALAESIELWGPRLQEIEKLT---------------------------AKQAHHIDSGTICTEELRPEQVQTADSSKVTTSSLPKENDPLECPSEDTETGAS---NSQTVLDKNFSIDQMLASTVNVYS-DKKSIRKILTQLLPSGNQVNPLQSPFP-AQDHLTLPLGSIPIHVRETDLSSVIAYSLTSMDYQKAIDEAEANSNAAHSSPQLKRKIPLAESVSDAEDSPSLSRTSSNTSAAPNASVPSPATAASESEEKSKERIKQPPSPHITLAFQDHSCQFQCKIYFAREFDAMRSKSLKPPK-LDKSLYRRLEKSKMREELRISQSRTGSEMELVRKPSDVGAPRTTEDDSNQEEDARIALARSLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAKIFGVFRVSVKKKDSF-VER--SVMVMENLFYGCNIENKFDLKGSERNR--LVDPSNQQGEIVLLDENLVQMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVGLDKKNGVLVLGIIDYIRTFTLDKRVESIIKGSGILGGK--GKDPTVVNPERYKQRFIDAMDRYFLTVPDRWEGLSKV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34756-1", "uniprot_id": "FAB1_YEAST", "id": "P34756-1", "name": "1-phosphatidylinositol 3-phosphate 5-kinase FAB1", "aln": "MSSEEPHASISFPDGSHVRSSSTGTSSVNTIDATLSRPNYIKKPSLHIMSTSTTSTTTDLVTNPILSNISVPKISPPTSSSIATATSTSHVTGTASHSNIKANANTSTSVNKKNLPPTTSGRIPSSTIKRYPSRYKPSHSLQLPIKNDSNFKRSSIYASKSTVTAIPIRNNRPISMQNSYARTPDSDHDDVGDEVSSIKSASSSLTASLSKSFLFAFYNNRKKDKTSNNGVLSKEYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCS-SCTLLIDGDRFGCHAKMRVCYNCYEHADTYEDSSDEENDSTMQLNEPRSRSRSRSSNTNPYSHSHSHLHLISQDNHNGTDLHDPVAATD-------NPQQQNEVYLLNDDDVQSIMTSGEDSKLFISTPPPPPKMAIPATKQGGSLEISFDSENDRALHYQDDNPGRHHHLDSVPTRYTIRDMDNISHYDTNSNSTLRPHYNTNNSTITINNLNNTTSNNSNYNNTNSNSNINNPAHSLRRSIFHYVSSNSVNKDSNNSSATPASSAQSSSILDPANRIIGNYAHRNYKFKFNYNSKGPSQQNDTANGNNDNNNNNNNNNNNNNNNSASGIADNNNIPSNDNGTTFTLDKKKRNPLTKSKSTSAYLEYPLNEEDSSEDEGSMSIYSVLNDDHKTDNPIRSMRNSTKSFQRAQASLQRMRFRRKSKSKHFPNNSKSSIYRDLNFLTNSTPNLLSVVSDDNLYDDSSPLQDKASSSAASRLTDRKFSNSSGSNNNSNSNSNINTDPWKRIASISGFKLKKEKKRELNEVSLLHMHALLKQLLNDQEISNLQEWITLLDGALRKVLRTILN-ARDLNTLDFRQTYVKIKRISGGSPQNSEYIDGVVFSKALPSKTMPRHLKNPRILLIMFPLEYQK-NNNHFLSIESVFRQEREYLDKLVSRLKSLHPDIIYVGANVSGYALELLNDSGIVVQFNMKPQVIERIAKLTEADIAISVDKLATNIKMGECETFEVKSYIYGN-ISKTYTFLRGCNPELGGTILLRGDSLENLRKIKQVSEFMVYAIFSLKLESSFFNDNFIQLSTDVYLKRAESKKLQ-----------------------------VFEGYFADFLIKFNNRILTVSPTVDFPIPFLLEKARGLEKKLIERINQYESESDLDRQTQLNMLQGLESTITKKHLGNLIKFLHEMEIENLELEFQKRSRQWEVSYSSSQN----LLGTGSHQSITVLYSMVSTKTATPCVGPQIVTIDYFWDSDISIGQFIENVVGTARYPCQQGCNGLYLDHYRSYVHGSGKVDVLIEKFQTRLPKLKDIILTWSYCKKCGTSTPILQISEKTWNHSFGKYLEVMFWSYKDSVTGIGKCPHDFTKDHVKYFGYNDLVVRLEYSDLEVHELITPPRKIKWKPHIDIKLKVELYYKILEKINNFYGSVLSRLERIKLDSMTKDKVLSGQAKIIELKSNATEEQKLMLQDLDTFYADSPCDQHLPLNLVIKSLYDKAVNWNSTFAIFAKSYLPSETDISRITAKQLKKLFYDSSRKDSEDKKSLHDEKAKTRKPEKNELPLEGLKDVEKPKIDSKNTTENRDRTNEPQNAVTITTFKDDTPIIPTSGTSHLTVTPSASSVSSSLTPQTEERPPISRSGTGISMTHDKSTRPNIRKMSSDSSLCGLASLANEYSKNNKVSKLATFFDQMHFDALSKEFELERERERLQLNKDKYQAIRLQTSTPIVEIYKNVKDAVDEPLHSRSSGNNLSSANVKTLEAPVGEHSRAN------NCNPPNLDQNLETELENSISQWGENILNPSGKTTASTHLNSKPVVKETSENPKSIVRESDNSKSEPLPPVITTTTVNKVESTPQPEKSLLMKTLSNFWADRSAYLWKPLVYPTCPSEHIFTDS--DVIIREDEPSSLIAFCLSTSDYRNKMMNLNVQQQQQQQTAEAAPAKTGGNSGGTTQTG------------------DPSVNISPSVSTTSHNKGRDSEISSLVTTKEGLLNTPPIEGARDRTPQESQTHSQANLDTLQELEKIMTKKTATHLRYQFEEGLTVMSCKIFFTEHFDVFRKIC--DCQEN------FIQSLSRCVKWDSNGGKSGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTG---KANEVLLDENMVEYIYESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGIDNEGYTLTVGIIDFIRTFTWDKKLESWVKEKGLVGGASVIKQPTVVTPRQYKKRFREAMERYILMVPDPWYREGN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::: . . .. . * .: . : . .. . . . . .: : . : . * * : . . . * * : . .. :. :.:** *...***:.*.:.*.****:****:******* .*. : * : ..::.* * : . :: .*: : .:.: . . . .: ..: : . . : : . . : * : .. . . . . . * :. . : : :. : . : : . .. . ... : .. . : .. ::: . :.* *.: * :. . .* * ** *:* ..:. .* :: . . . : : :*::*::.** :* :.*.. :* :. * * : *:***: .: * : :* *:.:. **:*:* : *: ..:* :: * .*: * ::* . :.: :::* .*::*::: : *:. *::. * ::* *. * :: : ** *:. * * *** * :* ::*.: :: . : :** **: ::* : . . : :. . :. . . : :. : . . * * * : . . . . . : . : :: : . * . : :: . * * . . . . :: :: . : * . : : : *: . . : .. . : : : .* : .: *: : * .:. . :: ::. . : . .: : .: .: . ::.* .: .. .:: :: : .: . . . . .: : : : :: .. : : . : . . * . :*: : : :: . . : . . . :*. : :::: . . : : : * : **:**:.*: :*:. : : : . :. . ... : . . . : : : . ::.:. : .: . . ::: : :**.:. *::.*****: * * ****::*:: :: * *** ** *: . . ** ***::*.::: *.. . . .:::****** : . ****** *** . : ******::: ..*::: .: * :** :: *: ** . ::****::* *. *.:****:***** **::* :* .*::** * ****.*. *: ** :**::*:* *** * . ", "identical_positions": 216, "similar_positions": 478, "identity": "9.15%" }, { "cls_id": "homologset.agr.SGD:S000001917", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W47-1", "uniprot_id": "WIPI2_MOUSE", "id": "Q80W47-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLAS-QSGEAG--AGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEA-VREK----------------------PPEEPTTWTGY--FGKVLMASTS--YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDL--------------GAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY57-1", "uniprot_id": "WIPI2_RAT", "id": "Q6AY57-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLAS-QSGEAG--AGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEA-VREK----------------------PPEEPTTWTGY--FGKVLMASTS--YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLVTQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDL--------------GAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4P8-1", "uniprot_id": "WIPI2_HUMAN", "id": "Q9Y4P8-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLAS-QSGEAG--AGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET-VKEK----------------------PPEEPTTWTGY--FGKVLMASTS--YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRL---------AYTDDL--------------GAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P910-1", "uniprot_id": "A0A8M1P910_DANRE", "id": "A0A8M1P910-1", "name": "", "aln": "-MNLAS-QSGEAG--CSQLLFANFNQDNT------------------SLAVGTKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVSLK-----APRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPSGLCALSISNDNCYLAYPGS--------------------------------------------------------------------ATIGEVQVFDTVNLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMEGLYLSASSNTETVHIFKLET-QREKSV--------------------PQEEPTTWTGY--FGKVLMASTT--YLPAHVTEMFTQGRAFATVRLPFSGHKNICALAIIQKIPRLLVAAADGYLYLYNLDPQEGGECTLMKQHKLDGSAEPANEILEQTAHDRPLVAQTYSAAVAKG--------------------YSEDQ--------------GAVGGAGVEDDMNTLH---------------------LDEE--NEQPPLILETD------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R3E3-1", "uniprot_id": "WIPI1_MOUSE", "id": "Q8R3E3-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-MEAEA-ADAPPGRVEAALSCFSFNQDCT------------------SLAIGTKAGYKLFSLSSVE-QLDQVHGSNEIPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------QSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKMEH-LTDS----------------------RPEEPSTWSGY--MGKMFMAATN--YLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTTE---ENKENDLRPSLPPSYAATVARPSTSAASTVPG----------YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGSQKGKTKQS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MNZ9-1", "uniprot_id": "WIPI1_HUMAN", "id": "Q5MNZ9-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-MEAEA-ADAPPGGVESALSCFSFNQDCT------------------SLATGTKAGYKLFSLSSVE-QLDQVHGSNEIPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------LTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQ-VTNS----------------------RPEEPSTWSGY--MGKMFMAATN--YLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTE---ENKENDLRPSLPQSYAATVARPSASSASTVPG----------YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGNQKGKTKQS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2Q1U4-1", "uniprot_id": "A0A8L2Q1U4_RAT", "id": "A0A8L2Q1U4-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-MEAEA-ADAPPGRVEAALSCFSFNQDCT------------------SLAIGTKTGYKLFSLSSVE-QLDQVHGSNEIPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYCYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPSNPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------QSTGEIVLYDGNSLKMVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQ-LTDS----------------------RPEEPSTWSGY--MGKMLTAATN--YLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTAE---ENKENDLRPSLPPSYAATVARPSASTASTVPDNL-----VPWKSEGQNEAVLTRSLPQKSGQPLSGGFGKNKESGRNGMQSMLWAERGGRQEAWAPHCLSHRPWSAPLPKPLSLGCQWARRMLESHNAIQATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PER1-1", "uniprot_id": "M9PER1_DROME", "id": "M9PER1-1", "name": "", "aln": "MMSLLGRTDVDAG-----EVFVNFNQNIT------------------SLAVATSGGYSLYSLGSVDSTLDKIYHTK-SDELFLIERLFESSLVAIVSQR-----APRKLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEESLYIHNIQDMKVVHTIRDTPCNPQGLCALSSSSEHCYLAYPGS--------------------------------------------------------------------VTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPSGTEIATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTETVHIFRLDRSATETAEG-----------------HGSKQSSDDWMGYSFFRFLSKTVTS--YLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIASQDGYLYVYSIPTVEGAECQLIKRHDLRLEDHYA---MDIKVDSPQTLGLNSGVSIGGAAGVPPSSASA----------------------------AGAGTGGSGGDGKSAVS-----------------VTGGVDKP--SSSYASAVKGDDPVGPSSA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIE1-1", "uniprot_id": "Q9VIE1_DROME", "id": "Q9VIE1-1", "name": "", "aln": "-MTTYQ---------------MNFNQDFT------------------SLSVLSPTGLRLFSISSQD-KVEEIFAKDNTEQIRIVERLFNSSLVVLVTAQ-----KPNCLKMLHFKKKQDICNCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDMKILHSIENIAPNEQGLCALSLN---SHLAFPVC--------------------------------------------------------------------QTSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGALLATASERGTVIRVFCVKNGQRVQEFRRGVS-CVRIASLVFSASGDFLCASSNTETVHVFKIDTRAVETVELKAIADVAAKSENSAKEAVASTAAEESCRPVASWGGMFSKAVSSLLLPTQVSEVLAQDRSFATVQLAQGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGGPCKLMSVHDLRGALEDVIELELSESVQRSQTKPSNPSTVTQPSLTMLKSCAASVLIE-----NPDPMQ------------DNSYASILKGDQADAMS-----------------DSAKFRKLCDAIDTPTKLYDERQFPPVAITAKD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43601-1", "uniprot_id": "ATG18_YEAST", "id": "P43601-1", "name": "Autophagy-related protein 18", "aln": "-MSDSS----------PTINFINFNQTGT------------------CISLGTSKGFKIFNCEPFG-----KFYSEDSGGYAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQIYIYDINTMRLLHTIETNP-NPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTY-ATRIYSISFSEDSQYLAVTGSSKTVHIFKLGHSMSNN----------------------KLDSDDSNMEEAAADDSSLDTTS----IDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSRRAARTLGQIFPIKVTSLLESSRHFASLKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSASTESYHEP---------------------------VMKMVPIRVVSSDGYLYN---------------------FVMDPERGGDCLILSQYSILMD-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*** * .:: : * ::. . . ::* **.:**:.:* *. :.: : ** **: :.. **.:::*:.**:* * *.::*::*. *:::::: . * ** *:* . .:*.:* . *:: ::: .*: * **. ::*:::. .*: :*:**::**:**** *.:: ::*** . * *: ** . :* :..::***:*:: :. .. ::: * : : .: . * :: .. . . : : . . : ", "identical_positions": 66, "similar_positions": 114, "identity": "10.59%" }, { "cls_id": "homologset.agr.SGD:S000001918", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPW1-1", "uniprot_id": "D3ZPW1_RAT", "id": "D3ZPW1-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFVVELDGTR-----AGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA------------------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------IVMLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT---------RGLVSLSAKIDRKGYTPGEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------CAVVASVDGEPVGPGRRALWPGR------------ALRIPPVG---PSILHCRVLSVDYSLKVCVDIPGSS----KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL-------------------------------------------------------------------------------CALMERPEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTE-----------------------------------------GPYFACLQEFRYRPPPLYS----------------EEDPNP-PSEAARPRCMTC-------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D668-1", "uniprot_id": "ARRD2_MOUSE", "id": "Q9D668-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFVVEIDGAR-----TGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA------------------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------IATLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARCARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT---------RGLVSLSAKIDRKGYTPGEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------RAVVASVDGEPVGPNRRALWPGR------------ALRIPPVG---PSILQCRVLSVDYSLKVFVDIPGSS----KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL-------------------------------------------------------------------------------CTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDLGVTTE-----------------------------------------GPYFACLQEFRYCPPPLYS----------------EEDPNP-PSEAVRPRCMTC-------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBH0-1", "uniprot_id": "ARRD2_HUMAN", "id": "Q8TBH0-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFSVQLDGAT-----AGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSA------------------------------------GSST-AYTQSYSERVEVVSHRATLLAPDTGE---------TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-APQAGAREKVARSWYCN---------RGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQK------RAVVASLAGEPVGPGQRALWQGR------------ALRIPPVG---PSILHCRVLHVDYALKVCVDIPGTS----KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRL-------------------------------------------------------------------------------GALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLE-----------------------------------------GPFFAYIQEFRYRPPPLYS----------------EEDPNP-LLGDMRPRCMTC-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPQ9-1", "uniprot_id": "ARRD3_MOUSE", "id": "Q7TPQ9-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLN-----DSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT---------SGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS---PSILDCSIIRVEYSLMVYVDIPGAM----DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMSMNWLA-------------------------------------------------------------------------------LALPERPEAPPSYAEVVTE-EQRRNNLAPVGACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR-------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TXF1-1", "uniprot_id": "ARRD3_RAT", "id": "Q6TXF1-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLN-----DSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNCEE---GFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT---------SGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWDGK------------LLKIPPVS---PSILDCSIIRVEYSLMVYVDIPGAM----DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLG-------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR-------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96B67-1", "uniprot_id": "ARRD3_HUMAN", "id": "Q96B67-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLN-----DSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT---------SGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS---PSILDCSIIRVEYSLMVYVDIPGAM----DLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLS-------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSADDRPSCPSR-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F4-1", "uniprot_id": "ARRD4_MOUSE", "id": "A0A0B4J1F4-1", "name": "Arrestin domain-containing protein 4", "aln": "MGGEAG---ADGPRGRVKSLGLVFEDES-----KG---CYSSGETVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGA------------------------------------RVCIGGGSPAASSEVEYLNLRLSLLEAPAGEG--------VTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVLERP-QVPDQSVRRELQVVSHVDVN-TPPLL-TPMLKTQEKMVGCWLFT---------SGPVSLSVKIERKGYCNGEAIPIYAEIENCSSRLVVPKAAIFQTQTYLASGKTKTV------RHMVANVRGNHIGSGSTDTWNGK------------MLKIPPVT---PSILDCCIIRVDYSLAVYIHIPGAK----RLMLELPLVIGTIPYSGFGRRNSSVASQFSMDMCWLA-------------------------------------------------------------------------------LALPEQPEAPPNYADVVSE-EEFSRHVPPYPQPSDCDGEAC-----------------------------------------YSMFACIQEFRFQPPPLYS----------------EVDPHPGDAQETQPVSFIL-------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCT1-1", "uniprot_id": "ARRD4_HUMAN", "id": "Q8NCT1-1", "name": "Arrestin domain-containing protein 4", "aln": "MGGEAGCAAAVGAEGRVKSLGLVFEDER-----KG---CYSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCP------------------------------------RASASTAALAVFSEVEYLNVRLSLREPPAGEG--------IILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERP-KVPDQSVKRELQVVSHVDVN-TPALL-TPVLKTQEKMVGCWFFT---------SGPVSLSAKIERKGYCNGEAIPIYAEIENCSSRLIVPKAAIFQTQTYLASGKTKTI------RHMVANVRGNHIASGSTDTWNGK------------TLKIPPVT---PSILDCCIIRVDYSLAVYIHIPGAK----KLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLT-------------------------------------------------------------------------------LTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVC-----------------------------------------CPVFACIQEFRFQPPPLYS----------------EVDPHPSDVEESQPVSFIL-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND---------PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG----------------------------------------------SQQCKQTLDYLRYEDTLLLEEQPTAGENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP---------DGRVSVSARIDRKGFCEGDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVF------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR---PSILGCNILKVEYSLLIYVSVPGSK----KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID-------------------------------------------------------------------------------LNIPDTPEAPPCYMDIIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNNNNVQ---------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND---------PEKVYGSGEKVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQG----------------------------------------------SQQCKQTLDYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP---------DGRVSVSARIDRKGFCEGDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR---PSILGCNILRVEYSLLIYVSVPGSK----KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID-------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNN--VQ---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND---------PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG----------------------------------------------SQQCKQTSEYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQETKKNFEVVDLVDVN-TPDLM-APVSAKKEKKVSCMFIP---------DGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR---PSILGCNILRVEYSLLIYVSVPGSK----KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWVD-------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDMDGSQD-----------------------------------------SPIFMYAPEFKFMPPPTYT----------------EVDPCILNNNVQ--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KN1-1", "uniprot_id": "ARRD1_MOUSE", "id": "Q99KN1-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEIRLSQ---------GRVVYGPGEPLAGTVHLRLGAPLPFRAIRVTCMGSCGVSTKAN----------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPAGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK---------TGNVVLTASTDLRGYVVGQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRRAQWQEQ------------ILVPALPQ---SALPGCSLIHIDYYLQVSMKAP-------EATVTLPLFVGNIAVNQTPLSPCP---GRESSPG----------------------------------------------------------------------------------TLSLVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVT----TTEPWVQVGSPARHSLHP-PLCISIGATVPYFAEGSAGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNL6-1", "uniprot_id": "ARRD1_RAT", "id": "B0BNL6-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEIRLSQ---------GRVVYSPGEPLAGAVHLRLGAPLPFRAIRVTCMGSCGVSNKAN----------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPPGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK---------TGSVVLTASTDLRGYVVGQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRHAQWQEQ------------ILVPALPQ---SALPGCSLIHIDYYLQVSMKAP-------EATVTLPLFVGNIAVNQTPLSPCP---GPGSSPG----------------------------------------------------------------------------------LLSPVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSTTLGSVSVT----TIEPCVQVGSPARHSLHP-PLCISIGATVPYFAEGSGGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAGGTDVGLIPGS------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5I2-1", "uniprot_id": "ARRD1_HUMAN", "id": "Q8N5I2-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEISLSH---------GRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKAN----------------------------------------------DTAWVVEEGYFNSSLSLADK--------------GSLPAGEHSFPFQFLLPAT-APTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASATKKFSYKLVK---------TGSVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHD------VRTIAEVEGAGVKAWRRAQWHEQ------------ILVPALPQ---SALPGCSLIHIDYYLQVSLKAP-------EATVTLPVFIGNIAVNHAPVSPRP---GLGLPPG----------------------------------------------------------------------------------APPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG-----APEPCPQDGSPASHPLHP-PLCISTGATVPYFAEGSGGPVPTTS----------------TLILPPEYSSWGYPYEAPPSYEQSCG--GVEPSLTPES------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7Q5-1", "uniprot_id": "A0AB13A7Q5_DANRE", "id": "A0AB13A7Q5-1", "name": "", "aln": "-------------MGKVQEFEITFTN---------NKVVYNPGESISGTVRIKSSHSLQFKAIKVCCVGSCGISSKLN----------------------------------------------DASWMLEEKYLSSTLSVADK--------------GTLPPGEHSFPFQFLIPAS-VPTSFEGPFGKILYKIRAFIDTPRFSKDYKAQRPFYLLNVLNLNELPDIE-QPSCAVTTKKFNYLLVK---------TGTLMLKAYTDLRGYTPGQVIKLSAEIHNKSGKDTGYVMASLIQRVSYKTKRPVFD------LRPIAEVEGAGVKAGKHAEWREQ------------IIVPPLPQ---SGLTGCNLIDIEYFIQVSLKSP-------EAAVTLPIYIGNIAVNLTPSIPHPMAHGVPMPTGPSL-------------------------------------------------------------------------------NPAAVVPSAPPVEEELAGQLAAGG--GDSEEIPTKSHSQQDPSGAPLSVAPYGHASGPVLPQSQQHVQSTDGSAP-LFCLSTGATIPFFTDGNATPVPTSC----------------PLILPPEYSTWEYPHEPPPTYEESCSSNNSSFNSSMR-------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT80-1", "uniprot_id": "A0AB32TT80_DANRE", "id": "A0AB32TT80-1", "name": "", "aln": "-------------MGKLQEFEISFDN---------NKTVYSPGESLTGTLKISIAQSIQCKAIKVNCQGFCGVTSKSN----------------------------------------------DTDWTDEEQYFSSSVSIADK--------------GTLKEGEHSFPFKFLLPAA-APTSFVGPYGQIMYRVRAFIDTPRFAKDYKIEKPFSMTNTLNLNEVPGIR-EPSSSSVTKNFSYMLVK---------NGTVVLNAKTDMRGYIAGQIIKVSAGIENKSDKTTGHVVASLMQKVTYNTKKQTYD------LRSVAEVEGPGVKGGNKSEWNQQ------------IIVPALPH---SSLSDGNLIQICYYIQVYLKYP-------EVALTLPICIGSVALDPSQPSHSQT--VAPMPAPR---------------------------------------------------------------------------------ITPAPSPSAPESEASNLPPRPAPKPAPKPRPRSTHASPSAPPVDLYPQLPSVSNYNGEMLKSPHQEPGSQGPVSPNAFSYAPGLSFRQRQSSSGPSAPPLS----------------LSSSSQDRNQMPSSASVPPSYRSSAYPQATNSEVLDESSSKNW-------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------MVICEIEFCNN--------SQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHD-------------------------------------PDDQSNGESFNGHVDYLATRAYLHGS------SSS---IEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRP-WKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCR---------SSPLSMRLSVPQSGFVPGQIVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSA-DTNKDRFEMVLKTGGGVSTKCRQQFTFD------------LKVPPTPP---TCFNLCSIIQIGYQVEAEARVKGCHG---GQSLHMPITIGSVPLT-KQLQKE--PRTWGEVLPPQQL----------------------------------------------------------------------------DAKALILIGSEQNGEALGSPNPWAADPSIAPPSYAEAKHISPDPHKFSKSKKKSQKRG------------VKGSQERKAETIVFSPLYAVFDLSNQVDEMT-------------------LRANEPKTDG-----GYVNEGVEKSTWL---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MGIICQILFHNN--------TQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTD-------------------------------------SNNKSTSESYNGFEKYLSSKVYLLGS------EIS---PEMALEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQP-WKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFR---------SDPLTLELNLPQTGFVPGQTVPANVLIGNES-KIRVHEVKVGLSMMITYYSDLSSG-SKCERKSVAKLKADG-VLRNSRKMYDFQ------------LMIPSTPP---SCFHLCRIIKIGYQIEVVAKVKGMHI---NGTLIMPVTICGVPISPSAVQYT--PQSSGPEAPEQ--------------------------------------------------------------------------------RALTLIEGEGAFAPAAPPYPWSEGSTLSPPNYAEAMHSHSDSEKQSESGNAQEKS--------------------------YKPLYPVFDLSTSTVEKS-------------------KEAALDKEE-------------KK-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MTVTCEIDFDNN--------PHGTYFGGEVLTGRVTLKLDKMKLVKAITLNITGYAETRWIERVT--------------------------------------TNRRRRRRTFCGREDYIASKTFLVGS------NLS---SQVSIEAGIHTYNFVCLIPTE-CPSSFEGSHGRVRYMATVTLVRP-WKFDQSYTRCFTVLKVMDLNFDSPLLRVPAHSETSKTYCCWPCR---------SDPLALQLTVPQTGFVPGQNVPLSVLVTNDS-HIPVEQLLISFVMLVTYHSKPPSMPNTTSERLVVNTFKGDAVQRNCKKLFSYE------------IRVPATPP---TCFNLCGIIQIAYQVEVEARVKGCHN---NEVVTIPLTIGSVPLA-QHVPIQ--PRGFVPQLNVN------------------------------------------------------------------------------------ELAVEEVATAPNSSSPWSVDASIPPPNYQEAVHMRSTAATRSDDLDDPEPVP------------PN---TLSLDGGAYKPLYPVFDIPSPSAPPP-------------------TDYTQNYMAERAFVNPAMDVDKDKGTWL---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MVVTCEISFDNN--------KHGTFYAGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLG-------------------------------------STKL-----YVGREDYLSSNTYLVGSEQNNTHNNT---HRLTIEAGVHSYNFTCQLPYQ-CPSSFEGRHGCIRYIVKVLLIRP-WKFDQAYTKGFTVLKMLDLNFDTPQLKSAAHSEGYRTFCCGPCK---------TDPLKLELHLPQAGYVPGQKIPVTIVVVNNT-AVAVSEIRLSLVMLVRYYSVSPEH--SRVERLIISRAKGESVLKQCTRSQTID------------LPVPSTPP---TCVELSNLIQIAYQLEVEALVKSLRE---QQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDS-----------------------------------------------------------------------------RRNPPDELPMVTALESLPSDLASSAADSALP-NYEESRHTQRGNINEEELHAFGSNE--------------------------FAPLYPVYSIPSPTPVLT-------------------ANARNAGFVN---------QSFVK-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPSSCSFELDR---------REPIYYSGETVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTR----------------------------------GGKTEHYTEYFRGKQQYLYTRTSVFGS--------------GNLPPGTHTYNFCIPLPLE-CPSSVVAQYGKIFYEVSVVIDRQ-WRFNNVFKQPLTVIQTYNLN-MSPQLLMPLVREDIKHFCCWPCS---------SGPVLSTLTIPFGGYAPGQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPHHKTREKEHSLNKSCQQERVLRLSKKKIEGT------------LAIPAVPPS--SRTEG--IISVSYQVILTISTGDCHV---DSDFEVPIVIGTIPLIQS-----------------------------------------------------------------------------------------------------AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQ------------------DEHNRTDDFIPRYPMYTNFAMPSAPP------------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHZ9-1", "uniprot_id": "Q9VHZ9_DROME", "id": "Q9VHZ9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPTTCVFQLDR---------LNPVYNSGEYISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMS----------------------------------------GKSE--TANYSGHQQYLHSRTNVFDN--------------TLFRAGVHVYVLTLRIPPD-CPSTCKGPYGYIAYTISLTIDKP-WGFDEVFRKPIIVVQTLDLN-YNAEFSLPVKDENLKYLCHWPCI---------SGPICSTLTLPASGFTPLQEVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKRN-FYSKTLVKELISDRTLRLSKRQYESS------------ICVPMDTPR--STLNPNYIVFLHYTLQVKLKTGYFHY---DTDLSVPIIVGTTSLQHLRDSVHTQQPVRRTPTPERQRLIERV-----------------------------------------------------------------------TPRPPTVEEDSAGEADPATDEPHRVIEDDEPPSYDSCLPPSFSFATLAGSQQTLGSN------------------AAVVLQRIHLPKFPGFSTLIGTAPAHGMEDSGLDMHMYRSYGSLNTDHTGRSLDTFGSLCGPLSEHVEEQEQEAEENLDVTAQVHRPIQRATVSEVENVLQDEHLF------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------MGLKGCELQLDN---------PWNTYYAGQTVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTS---------------------------------EGKTENEVTQLKGHEEYFKIQYYLLGGKNSS---------ETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRP-WKFDQDMKMAFTVIAPVDLN-LNPRVKEPFKLELEKSFCCFCCR---------SGPLAVITNIPQTGFVSGQVLPITCEVDNTS-NVNLTAVKFELRKLVTFHTNQPRS-EKRESKVIIANLSVGPVNGGESRTFTQQ------------MEIPALPP---TNLLNCGIIALDYDLHVECEVSGPHR---NLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS--------------------------------------------------------------------------------LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIP-----------------------------------------PPQFVETQYRAPTIAGRDD----------------SEHTQMIGDGAFAPRYPTFQFNNATAPPASQ-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPIECLISFDNN--------PQGVYYAGQELSGVVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYP---------------------------------------RDSERAMCRAYRSYLSSRSYVLGSCANN--------SSIDWPAGEYSYTFHVILPDN-LPTSFDGKYGQIHYEIITTIERA-ARHPKVFKLPFTVIQPLDLN-ADAIYRVPLEILDRKRFWSFCCP---------TGPLTVKFSTPYCGYAPGQKIHFVLYINNES-SIDIIECEVKLKQEVSYESHDPQHEYR-YDKHLIARKQFGNVLRWSRKVYRGY------------LDLPSIPP---TSVKPTCPISVNYSIKIIVNPTEFHW---KLKLKIPLTIGSIPIMDGPEALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQQRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDDTEFLTN----VSMSSILSAQADVTTSEPFKPRYPVYYDYETPTIPPET----------------LYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8K8-1", "uniprot_id": "Q0E8K8_DROME", "id": "Q0E8K8-1", "name": "", "aln": "------------MPRKLLKFLIIFDN---------TSLLYFPGQFLSGRVLIELQDETPALGLHFHVVGEGVVRNGRR----------------------------------------------QERTYDKENYIDFRMRLLGDVDQG--------GPAILSPGIHSFPFKLGLPLG-LPSTFLGRYGWIQFYCKAALREN-NGIIHKNHQVFIVMNPIDLNLEKPILAQPFTCEVEHKLGVVCVG---------GGQIKCRVSLDRGGYVPGENILVTAFISNYS-NVSIKRTKASLTETIEYLARGKVVQTE---KRELAVLVRGKIRPGAKDEWHNE------------LYVPPLPP---TNLHGCHLIKISYDVFFVIEPKSMEK---EIKLQLPIVLATYPFRHSGDAVN------------------------------------------------------------------------------------------------ANTWPESVLKPDTHTHYPSTLPIFRPWLHEKPIEA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU7-1", "uniprot_id": "Q9VGU7_DROME", "id": "Q9VGU7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MSSKVNFVFDSN--------PLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGE---------------------------------DGKTTKSLVTHTTTEVYYSTDQPVYGQAGGS---------QLELPTGKYVFPFRATIPPN-APTSFNGAHGQIKHEVTLTIDRA-VRYNNTFKQCFTVILPHDLN-RRLEYKEPLQRLESKSFWWGSIFG-------AHKPMIMDVSTSYSAYVPGQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGEVLKHNKAKFDEF------------LTVPPTTP---STQSEKDPIRVSYTLRFIAKTFKLHGGG-DLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHPG----------------------------------------------------------------------------SPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATP------------------------VKFTPNPVSPAAQKSPPYTTNTP---------------VASPPGGNFEVLGFSIPPDYKPTPSAPAASSTGGIGWK------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "------------MQRSIKELSVRYDPIN-------ETNTFTNGDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGD------------------------------------DERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRS--WKPTSSAQAEINFAPRNFG-TNDHLLQPQSGTEDKKMKLFGSG-----------KMSMTVTTDKTGYMLGEIIRVSVDIDNSSSRDIKLKYSLKQLQTFIAGRSTTHA------HKDIVKETKDCIPSGGKTRFVVD------------IKLPHDIM---VTIENCRIIKVQYELKVYLDVSFAS----DPTVKFPVVIIPPLQQCPPWHDPPPPYMPPQP---------------------------------------------------------------------------------------NLVPYPGGAAPPPAGLYPNLYDPVPPYPGTAAGTFPNP-----------------------------------------NAMLPGFHPAPSAPVYDLN-----------------QSTKESFPNAPH-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "--------------MESERLRITLDS---------ADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNS----------------------------------NNNEYSRSLFYTSKEVYEHSETPLPDFEPRG----------LELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP-WTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR-----------PITLLALLPEDFAVRGEPLRICATVINNS-TTAVEKLRFTVLQYVTYYSHVPLR-VQKVECIAVATKETGSVQKKTERSFAHE------------LLLPDGAQP--TDEQMSGVITIVYELRVEAVLRGFFK---NLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGN-----------------------------------------------LFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTG----------GAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K7-1", "uniprot_id": "Q9I7K7_DROME", "id": "Q9I7K7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MSHRCEIQLDN---------PRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKK------------------------------NEQPVVVQSLDFDYRVDYFAKIDYFVGSEAAQP---------QIMEAGTYNYGFHVKLPKN-CPGNFEGGHGHIRYTLQVLIHSSADRPLEVLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRLRFWMKP------------LHLQLQIPRQGYSPGAGISVHLKLHNPE-KLTLREAVYSLVQISTYVAHLKNK-----PKRLETKVERQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAAT--LTVAGCACLQLNYEVEVLVTTQQEKR---LIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEPTPP------------------------------------------------------------------------------------VETASTLIPNFSISTTSLASNFREAEFMVATNLNKT-----------------------------------------NKHYLSGEQLDFRPRYVYY----------------EMDQTQSEEVKSH-------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43602-1", "uniprot_id": "ROG3_YEAST", "id": "P43602-1", "name": "Protein ROG3", "aln": "----MGFSSGKSTKKKPLLFDIRLKNVDNDVILLKGPPNEAPSVLLSGCIVLSINEPMQIKSISLRLYGKIQIDVPLERPQDASSSSLSSSPPKIRKYNKVFYNYAWDNVNLKEYLSGLRGQSGLAGSSSSSNILGTRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAILPGSLPESVESLPNCFVTYSMESVIERSKNYSDLICRKNIRVLRTISPAAVELSETVCVDNSWPDKVDYSISVPNKAVAIGSATPINISIVPLSKGLKLGSIKVVLFENYQYCDPFPPVISENRQVTELNLEDPLNESSGEFNGNGCFVNNPFFQPDHSFQDKWEIDT----------ILQIPNSLSNCVQDCDVRSNIKVRHKLKFFIILINPDGHKSELRASLPIQLFISPFVALSIKPLSSSNLYSLFSTTNQKDENSSQEEEEEYLFSRSASVTGLELLADMRSGGSVPTISDLMTPPNYEMHVYDRLYSGSFTRTAVETSGTCTPLGSECSTVEDQQQDLEDLRIRLTKIRNQRDNLGLPPSASSAAASRSLSPLLNVPAPEDGTERILPQSALGPNSGSVPGVHSNVSPVLLSRSPAPSVSAHEVLPVPSGLNYPETQNLNKVPSYGKAMKYDIIGEDLPPSYPCAIQNVQPRKPSRVHSRNSSTTLSSSIPTSFHSSSFMSSTASPISIINGSRSSSSGVSLNTLNELTSKTSNNPSSNSMKRSPTRRRATSLAGFMGGFLSKGNKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * . : . * . : : : : . : : : : : : : .*. : ", "identical_positions": 3, "similar_positions": 22, "identity": "0.4%" }, { "cls_id": "homologset.agr.SGD:S000001923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69Z69-1", "uniprot_id": "ESCO1_MOUSE", "id": "Q69Z69-1", "name": "N-acetyltransferase ESCO1", "aln": "-----------------------------------------------------------------MSIQEKSKENSSIVTKESEDENLEEEVESSQNSPTKKSGSKEAVKTPVRFSNKSKTNESEFGMRMSTRSASCSADKTATNSFNKNTVTLKGQSQESSKTKKLCQEK--------LSLGILKGNEQLHRRSQRLQQLTECTTRSLRSREIHGQIQTVKQNQQSARREQCNSTQSKCNKVKVNQKHVKRKVLEIKSDCKEDRHSVTN------------EVINSPKGKKRKVQHQTTSTCSSQCNQGSEKCLQKTSRKEEIKPVPVTADIRKLKAATS----------------------------VVSKKNELRKSAHTQVSTSTKRPQ----------------IPLPLVPEHSDDQELEQAGKSKRG-----SILQLCEEIAGEIESDT---------------VEVKKESSCVESVKEEKPAEVKLQGTDAERQILHHKEANQDVRSNRFFPSRKTKPVKCVLNGINSSTKKNSNWTKIKLSKFNSVQQHKLDSQVSPKLNLLQTGLSTSVLEMPHPVSQS-----------------------------------TFLEMKAHG-NVTCQRDKMKGIKSEEVKINNIAIEINKATKRDPGNCNLDN--HIKPSPDSSLDNQMKLSCES--APDQNFSICSASEVETNPLENTAAASTLLSQAKIDE-------------------------------DRTFPGSAPNQQHSVLSDEASINRKNRDVPPNHSQLKHDSHLEITIPKSLKLKDSEKVDEK------------QLVIDAGHKRFGAVSCNICGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEY----PDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYS-----RTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQY----CGTGQFLVYNFINGQNTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWF5-1", "uniprot_id": "ESCO1_HUMAN", "id": "Q5FWF5-1", "name": "N-acetyltransferase ESCO1", "aln": "----------------------------------------------------------------MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTK-KKLSQKK--------LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN--KTSQKHVKRKVLEVKSDSKEDENLVIN------------EVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATS----------------------------VVPKKNEMKKSVHTQVNTNTTLPK----------------SPQPSVPEQSDN-ELEQAGKSKRG-----SILQLCEEIAGEIESDN---------------VEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQS-----------------------------------TFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLAN--EIKPS-DPPLDNQMKHSFDS--ASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDT------------------------------GENKFPGSAP-QQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEK------------QLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEY----PDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYS-----RTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQY----CGTGQFLVYNFINGQNST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLF3-1", "uniprot_id": "A0A8M2BLF3_DANRE", "id": "A0A8M2BLF3-1", "name": "", "aln": "-----------------------------------------------------------------MPGQKRKMSSSEPEVKKTKLDRNLVESDKSQKPKRGRPPKSKVLEAQPSRQKHQIDSREENGKPIRRSSRLKTPLKKGARARRRKDGEKPKVSEEKSSQKMPVLKKGNKKYVSRVKREKPIISETIKTVAAMFPVQIEHNYGRLFDMQAEEITLPKPDKIHVANKSEMQALHETQASKAEEQKELHAEPVEKITVSVDAKVDVMS------------KSPPPLEALFKVIQESSLTKHSFSGKDISDMDELEVVNTCSLQDSVQSTDVAKVFLQDSDAFLDDDVEIENCVVEIETYEDLDGDQGEVSKKQTSECVTCKEVNSSPSLPQESATDSSQELPKKQAMNPQARTKARLAALAEERAAAAKKPPPRHFNLLALCEEIADDIASDAPGASDKTTNEQQQEDHESEDVSECTEVSESKDASESKEVNESKDLSESKDASESKDVSENKEVSETETCEPEEVVSENTAPPGTPNEETADPRPEDGTPKKRFFLSQMSVPLKTQEKKKLSRFQRLRQVELQRD--------------------------------KLTWTRVKKLKSDQVNQAGSQKDSEASSVSPSPATTPAQVPTTESVPKVGSVEPKRVLPAQAPPMPNGITSPKPKPVVEYKPYTPRRKYSPDDFELDGFEEDTAKPAAPKNVG------------------------------KAEQSPSSAKVQPNPAVERKLCVPTTADSKSKSSPQQETAQQTQLENSNSSSVEPEQKKEDKNSPKPESPAA--QSSNEAGQKAFGAVTCNVCGMLYSPTSAEDESQHLLFHNQFISAVRYVGWKKERILGEY----PDGKIILVLPDDPKYALKKVEEIREMVDNDLGFQQVESKVPS-----QTKTFLFISNDKKVAGCLIAEHIQEGYRVIEESVLEG-SEGEKVMYERQRAWCCSTVPEPALCGISRIWVFSMMRRRGIASRMIECLRNNFIYGSHLSKDEIAFSDPTPDGKLFATHY----CGTSQFLVYNFVSGKRST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CIB9-1", "uniprot_id": "ESCO2_MOUSE", "id": "Q8CIB9-1", "name": "N-acetyltransferase ESCO2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MMATCTPRKRKRYTLNADNDDSLLTDISSSKLRCAENLFPSPNKKHNYQSSVQKEDK--SCSHQLHFPSSPLKTTENSRFSFANH-SSLFKPAMSTVSFYSKEK-YYLNPLERKLIR------------ECRSICLATESGDKPIPSVTENIQRKPVCTKK-NKKKQKSLTAKYQPNYKHIKSKSRNL-------------------------------KNSKPNQVTYKPVVD---------------------------------------------------------------------------------------QENSCFPAKNYPNSPPRVLSQKIKPQVTLQG-GAAFFVRKRNSLKKLPLEDK--PLLLQKNLPEVPEG------------------------------------------------------------------------------------------------APEAKQIPKSLLVDEKSSVKVQNARSKNEEKLRKNPSGAVVSSKECNLDKHD-FPSENSLDENKTIS-----------------------------------------------------------------PES-VYPIFNVSSVNTKRP--EEQSSVGSTACTNFLKQTNVPKNINSRDTNKGGKD------------QLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHRFLEGIKFVGWKRERVVAEF----WDGKIVLVLPRDPSYAIKKVEDVQELVDLELGFQQTVPVCPD-----KTKTFLFID-EKRVVGCLIAEPIKQAFRVLSEPS---------ASKECSRAWRCSDVPEPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKY----CNTPNFLVYNFHN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L7J5-1", "uniprot_id": "A0ABK0L7J5_RAT", "id": "A0ABK0L7J5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MPALEAAAGRAPASLTTAAGEVEYHDPGRRVATPAQNAKLEIPPARGNLVMMMATFTPRKRKRHTLKADNDDSLLTDISSSKLRFAENLYSSPNKKHNCQSSVQKEEK--PCSHQRHFSSSPLKTTENNMLSFANH-SSLFKPVVSTVSFYNKNK-HYLNPLERKLIR------------ECKSICLATKNEDKPFPSVTEKIQRKPVCTK--NKKRQKSLTANHQPNYKHVKSISRNL-------------------------------KNSKPSQVTYKPVVD---------------------------------------------------------------------------------------KENSCFPPENPPNSPPRVLSQKIRPRVTLQG-GAAFFVRKRNFLKKSPLEDKPLPILLQKNEPEVTED------------------------------------------------------------------------------------------------ALEAKQVPKSLLVGEKSNVELLDARSESEEKLGKNSSGAVVSSKECKLGKHN-FPSEKSL-ENKTIS-----------------------------------------------------------------SES-VYSIFSVSSTNTKRSPSEEQSSVGSTACTNFLKQTNVQKNINFRDTNKGGKD------------QLVIDAGQKHFGTTMCKSCGMIYTASNPEDEIQHLQHHHRFLEGIKYVGWKRERIVAEF----WDGKIVLVLPRDPSYAIKKVEDVQELVDLELGFQQVVPMCPN-----KTKTFLFID-EKRVVGCLIAEPIKQAFRVLSEPS---------TTKECSRAWRCSDVPEPAICGISRIWVFKLKRRKRIARRLVDTVRNCFMFGCFLSINEIAFSDPTPDGKLFATKY----CNTPNFLVYNFHS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q56NI9-1", "uniprot_id": "ESCO2_HUMAN", "id": "Q56NI9-1", "name": "N-acetyltransferase ESCO2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MAALTPRKRKQDSLKCD-----------SLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSALKTTEINRLPSANQ-GSPFKSALSTVSFYNQNK-WYLNPLERKLIK------------ESRSTCLKTNDEDKSFPIVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNS-------------------------------RNSKQNRVIYKPIVE---------------------------------------------------------------------------------------KENNCHSAENNSNAP-RVLSQKIKPQVTLQG-GAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVIEDSDVETVSE--------------------------------------------------------------------------------------KKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHKVDKNEAFSSEDSLGENKTIS-----------------------------------------------------------------PKSTVYPIFSASSVNSKRSLGEEQFSVGS---VNFMKQTNIQKNTNTRDTSKKTKD------------QLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKYVGWKKERVVAEF----WDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPN-----KIKTFLFISDEKRVVGCLIAEPIKQAFRVLSEPIGPE---SP-SSTECPRAWQCSDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKY----CNTPNFLVYNFNS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPR8-1", "uniprot_id": "ESCO2_DANRE", "id": "Q5SPR8-1", "name": "N-acetyltransferase ESCO2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MLSRKRKHGSPDAE---------SNPSKKQITSLRSSPRR-----TTRQKENIPISLNSPQKIPSTPKKTQRAFLLESPPKRVSPRKAVLGAGTFYSKQKPLYLTPLERKVLK------------EAKSPPSVTNKEPSRPPLTAANQVVKPAKKVQ--KKPRASAPQSNLKGYFTAKPKATKS-------------------------------SSDKQTDQVLKSTMAPISFSSM-----------------------------------------------------------------------KSKGKPKLVVGAAFFNTGKKPTSMYKKSAQNTKPKPTYEKPSIRKPVREKELVTAPGQRSPVRRAVFLKKQPEVEVS--------------------------------------------------------------------------------------------------HDKRESTQAPMSPQVLADVHGITKELRVVLRRSVSPETGSQDAPSEADSVFDVSDLLLPDHDSSHD---------------------------------------------------------------EEESSVYPIFGTKRPQKKGKLSPPLNSSTPSALTATPALKAKERSMLRREMKKQTDN------------QLIIDAGQKQFGATTCASCGMLYSTDSPEDNFQHTQFHQRFLDTIKFVGWKKERVVAEF----WDGKIILVLPDDPKYATRKAEDVRRIADSELGFQQITLSSPS-----SAKTYLFINTDRMVVGCLVAENIRQAYRVLEQQEKQKDMSKE-DFMEHHRTWCCSTVPEKALCGVSRIWVFSLMRRKSVATRLLDTARNTFMYGSHLTKEEIAFSDPTPQGKLFATKY----CQTPTFLVYNFIS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43605-1", "uniprot_id": "ECO1_YEAST", "id": "P43605-1", "name": "N-acetyltransferase ECO1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKARKSQRKAGSKPNLIQSKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKY-----------------HTLQLHGRKWSPNWGSIVYTERNHSRTVHLSRSTGTITPLNSSPLKKSSPSITH----QEEKIVYVRPDKSNGEVRAMTEIMTLVNNELNAPHDENVIWNSTTEEKGKAFVYIR-NDRAVGIIIIENLYGGNGKTSSRG---------RWMVYDSRRLVQNVYPDFKIGISRIWVCRTARKLGIATKLIDVARENIVYGEVIPRYQVAWSQPTDSGGKLASKYNGIMHKSGKLLLPVYI------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VS50-1", "uniprot_id": "ECO_DROME", "id": "Q9VS50-1", "name": "N-acetyltransferase eco", "aln": "METPTGSGRPSRMATPRLSERKRQLFGSPRSRLRQINDDEDDADVDSLGVLPLKTHVAANRKGRSLFAAVPGKSSSSANSSPETNKENKKTRGGVMTATAEQLPQLFTATMRLNSNSSSNSRNSSPRQTRVQRKRADSSMSSPTSSSEGTPSSRARNSIRRSPRTFSAQKDPDAFSSPESFQTRLSKVAAMLMKGQDSRSMLEKSKKKHNHSLKTTAQVHTTKPKKTSPAEESQSDDEKPSSSKNSRKNTEVRETRSSQIISPKTRNRRRPFTSADINCKTLKAAAHLHENMRSYDEEKTAAVKLENSRSRSKSPVEVFKSNDDAVKRNTGNTNNKTAKSSEVATAKRPESPGSSMKIDVEVPESDEEASNHKPQKRQHPETSTPVAPSADADSGSPQSKMRKVTLSSSIPTMAFYSHSGEAVTKSRRRPSISKNSLKQPTKISPTSRPLLGINKGVHHKIRKRHGFANRLPATDMDNILNSLSNERLKNLITTKREERAKVEEVHQILRNAKDPIKMAKPLSVIEADDANNNNNLPATAWQETSADFSDLSDVEDIDPIIEVEPIIPIIRHEPVQKSPTAEPADLSKRKFFKSGRRSSTCMEVRITDNIRASVSQGKIELVQTIRRKPRQVRVKSATIFSAEQATVDAILKNLDDTVVDEIVEANPVVQATPIDAEETTMETESLPDIIEYAPEANDVEIDPFAEFRQRLPYQTDDPNVVEQQQILLEFLISNNICTEKNFEIFIANPDDYKDEANQIVDNLYMVVNSEEAAQLAQMETVENTAVAIAPKQDAPAVEEVQPKLFPIFTQRLQPVVQKSLRRRPDTSMRLLTAAGGSNQYQIDAGQKAFGARQCQQCGLVYTVHEPEEELLHREYHN-SIHVLRFKGWIDEDIVSVYPEWASDGRIIRINERAPTARLDRLRDLIGVVDKELGYSSYIVPKIF--------VAFIAVRKQQIVGFCLVQPLSQAHR----------------FIQVDGTDYFSEESYPASCGVSRIWVSPLQRRSGIASKLLRVVQCHTVLGQEIARECIAFSTPTDDGRALARQF----TGLDNFLTYDQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : .* . * : ... * : :. . . : :*: : .. :: :.: :*. . . . .* : : : . . *:***** *: :* ::: : : * :. :*:* ** .* :* :: :* ", "identical_positions": 22, "similar_positions": 55, "identity": "2.02%" }, { "cls_id": "homologset.agr.SGD:S000001924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEH4-1", "uniprot_id": "A0ABK0LEH4_RAT", "id": "A0ABK0LEH4-1", "name": "", "aln": "MKRKSERRSAWATAPPCSRRSSSSSPGVKKSRSSTPQELHRLEQQDDLYLDITDRLCFAILYS--RPKSASNEHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLK---------------SITMLRKKIIHFTGTDQRKQANAAFLIGCYMVIYLGRAPEDAYRTLIFGDTA-YIPFRDAAYGSCSFYITLLDCFHAVKKAIQYGFLNFNSFNLDEYEHYEKAENGDFNWIIPERFLAFCGPHSRSR-----LESGYHQHSPETYIPYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFPDGSTPAEAIVQEFLDICENVEG---AIAVHCKAGLGRTGTLIGCYLMKHYRMTAAESIAWLRICRPGSVIGPQQQFLVMKQSSLWLEGDYFR-------------------QKLRGQENGALREAFSKHLSDVDDISING----LENQDSQEPEPYSDDD--EVSGV---------------------------------------------------------------------------------------------------------------------------------TQGDRLRALKSRRQPKTNAIPLTV----ILQSSVQSSKTPEPNL-----------------------------------------------SGSAGITKRTTRSASGKSSLKSLAPWRERRRRSALQHMPMLALCPAISRT----------KTVLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFY9-1", "uniprot_id": "CC14B_MOUSE", "id": "Q6PFY9-1", "name": "Dual specificity protein phosphatase CDC14B", "aln": "MKRKSERRSAWATAPPCSRRSSSSSPGVKKSRSSTPQELHRLEQQDDLYLDITDRLCFAILYS--RPKSATNEHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLK---------------SITMLRKKIIHFTGTDQRKQANAAFLVGCYMVIYLGRTPEDAYRTLIFGDTA-YIPFRDAAYGSCSFYITLLDCFHAVKKAMQYGFFNFNSFNLDEYEHYEKAENGDFNWIIPERFLAFCGPHSRSR-----LESGYHQHSPETYIPYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFPDGSTPAESIVQEFLDICENVKG---AIAVHCKAGLGRTGTLIGCYLMKHYRMTAAESIAWLRICRPGSVIGPQQQFLVMKQSSLWLEGDYFR-------------------QKLRGQENGPLREAFSKHLSDADDLSLNG----LENQDNQEPEPYSDDD--EVSGM---------------------------------------------------------------------------------------------------------------------------------TQGDRLRALKSRRQPKASAIPLTC----PLAVLT--------------------------------------------------------------------------SALCSVAIWWIVCD----YILPTLLFCLDGFRT----------Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60729-1", "uniprot_id": "CC14B_HUMAN", "id": "O60729-1", "name": "Dual specificity protein phosphatase CDC14B", "aln": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYS--RPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLK---------------SITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETS-YIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRAR-----LESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEG---AIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFR-------------------QKLKGQENGQHRAAFSKLLSGVDDISING----VENQDQQEPEPYSDDD--EINGV---------------------------------------------------------------------------------------------------------------------------------TQGDRLRALKSRRQSKTNAIPLTV----ILQSSVQSCKTSEPNI-----------------------------------------------SGSAGITKRTTR-----SASRKSSVKSLSIS----RTKTVLR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4D256-1", "uniprot_id": "CC14C_HUMAN", "id": "A4D256-1", "name": "Dual specificity protein phosphatase CDC14C", "aln": "------------------------------MRSSTLQDPRRRDPQDDVYVDITDRLRFAILYS--RPKSASNVHYFSIDNELEYENFSEDFGPLNLAMVYRYCCKINKKLK---------------SITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEAAYRILIFGDTP-YIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRAR-----LESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKRFLDICENAEG---AIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGLVIGPQQQFLVMKQTSLWLEGDYFR-------------------QRLKGQENGQHRAAFSKLLSGVDDISING----VENQDQQEPKPYSDDD--EINGV---------------------------------------------------------------------------------------------------------------------------------TQGDRSRALKRRRQSKTNDILLPS----PLAVLTFTLCS--------------------------------------------------------------------------VVIWWIVCD----YILPILLF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GQT0-1", "uniprot_id": "CC14A_MOUSE", "id": "Q6GQT0-1", "name": "Dual specificity protein phosphatase CDC14A", "aln": "-------------------------------------MAAESGELIGACEFMKDRLYFATLRN--RPKSTINIHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLK---------------SYSLSRKKIVHYTSFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTVLDCLQGIRKGLQHGFFDFETFDAEEYEHYERVENGDFNWIVPGKFLAFSGPHPKSK-----IENGYPLHAPEAYFPYFKKNNVTTIVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEG---AIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLKEKQASLWVQGDIFR-------------------SKLKNRPSSEG--SITKIISTLDDMSIGANLSKLQSTERIGENNFEDEDMEIKNNV---------------------------------------------------------------------------------------------------------------------------------TQGDKLRALKSQRHPRSSPSCAFR----SDDMKGHQRAMAQTFR---LSSSPQPTMSTMKTSKVCLSP------------SVTAKKISRGSLSSGANIRSFSINSRLASSLGNLNAGTEEPETKKTTSLTKAAFIASPFTS----------FLNGSTQTPGRNYPELNNNQYTRSSNSNSSSSSSGLGGNLN-SSPVPQSAKPEEHT--TILRPSFPGSLSSSSVRFLSRSIPSLQSEYVHY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B415-1", "uniprot_id": "A0A8I6B415_RAT", "id": "A0A8I6B415-1", "name": "", "aln": "-------------------------------------MAAESGELIGACEFMKDRLYFATLRN--RPKSTINIHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKPKKMFKNVPFLRKLESYSLSRKKIVHYTSFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTVLDCLQGIRKGLQHGFFDFETFDADEYEHYERVENGDFNWIVPGKFLAFSGPHPKSK-----IENGYPLHAPEAYFPYFKKNNVTTIVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEG---AIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFR-------------------SKLKNRPSSEG--SITKIISSLDDMSIAGNLSKLQSTERIGENNFEDEDMEIKNNV---------------------------------------------------------------------------------------------------------------------------------TQGDKLRALKSQRQPRSSPSCAFR----SDDMKGHQRAVAQTFR---LSSSPQPTVPTVKTPKVCLSP------------SVTAKRISRGSLSSGANIRSFSINSRLASSLGNLNSGTEETENKKTTSPIKAAFIASPFTS----------FLNGSTQTPGRNYPELNNNQYTRSSNSSSGGS---LGGNLN-SSP---SAKPEEHN--TILRPSFSGALSSSSVRFLSRSIPSLQSEYVHY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNH5-1", "uniprot_id": "CC14A_HUMAN", "id": "Q9UNH5-1", "name": "Dual specificity protein phosphatase CDC14A", "aln": "-------------------------------------MAAESGELIGACEFMKDRLYFATLRN--RPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLK---------------SYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSK-----IENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEG---AIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFR-------------------SKLKNRPSSEG--SINKILSGLDDMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGI---------------------------------------------------------------------------------------------------------------------------------TQGDKLRALKSQRQPRTSPSCAFR----SDDTKGHPRAVSQPFR---LSSSLQGSAVTLKTSKMALSP------------SATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTN----------LLNGSSQPTTRNYPELNNNQYNRSSNSN--------GGNLN-SPPGPHSAKTEEHT--TILRPSYTG-LSSSSARFLSRSIPSLQSEYVHY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVA4-1", "uniprot_id": "CC14A_DANRE", "id": "A0A0R4IVA4-1", "name": "Dual specificity protein phosphatase CDC14AB", "aln": "---------------------MTLDNLKHSAILSTLFKMADDNDLLGASEFIKDRLYFATLRS--KPKSTANTHYFSTDEEFVYENFYADFGPLNLAMLYRYCCKLNKKLK---------------SFTLTRKRIVHYTSFDQRKRANAAVLIGAYAVIYLKKTPEEAYRALISGSNASYLPFRDASFGNCTYNLTVLDCLQGIRKALQHGFLNFETFDVNEYEHYERVENGDLNWITPGKLLAFSGPHPKSK-----VENGYPLHAPEAYFPYFRKHNVTTIVRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDIITRRFLHICESTSG---AVAVHCKAGLGRTGTLIGCYLMKHYRFTSAEAIAWIRICRPGSIIGPQQHYLEEKQASLWAHGDSLR-------------------SKQ--RQYQDR--SVPQLISSMDNLSISTSIFKSHSLDRMEENDYAENDLGMT-------------------------------------------------------------------------------------------------------------------------------------QGDKLRALKGRRQPRSATTGAIR----VEDVKVHTRSPSQPLSRMKPPASSQGSISPLKSSKVPASSSS---SSSSSSVSASAKRIGRSSSSS-TNLKS----TRLASSLGNLYEPNTESISSGK-PPSPSSFTPHPVRT----------TYNYHYEVNN------NNNQYSTTSSPSKS-----LGYNLNHSGPSGASANARLSAGEQGHQRNPPAGLSGLSTRHLSRSIPSLQSEYVQY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BE48-1", "uniprot_id": "A0A8M2BE48_DANRE", "id": "A0A8M2BE48-1", "name": "", "aln": "-----------------------MKRKSERRCGSRKRICASLRDRSDIQLHITDQLYFALLHQ--KVRSTPDRHCFCIDEELSYENFYADFGPLNLAMLYRFCCKLKKKLK---------------SCAHAKKKIVFYTYGDRKKQANAAYLIGSYAVMHLQKTPEEAYSLLVS-QNAPYLPFRDASFGACMYNLNILDCLRAVHKALQFGWLDFTQFNVEEYEHYERAENGDFNWILPGKFLAFSSPHPKSK-----IENGYPLHAPEAYFPYFRKHNVTTIIRLNKKMYDSKRFTDVGFKHHDLFFVDGSTPNDSIVSRFLHICENADG---VIAVHCKAGLGRTGTLIGCYLMKHFRLTAAEAIAWIRICRPGSVIGPQQNFVDEMQSSLWAEGELYR-------------------QKINEQENGSAKTAVAGILSGVEDISING-TNKSTSQRKTASQNHTEEEEEDCAGL---------------------------------------------------------------------------------------------------------------------------------TQGDKLRALKSKRQSRAS-TGSIS----LEENTVHTKSTSKSLS---------------------------------------SEKRKRTRASLGSNRASSPLHSRLAKSLGSLQVVACET---------DGVFCDISDAS----------VAN--------------NNSFIKQ-----------------------------------------------SNIKHLR----SISSAAV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLW7-1", "uniprot_id": "Q9VLW7_DROME", "id": "Q9VLW7-1", "name": "", "aln": "-----------------------------------MLDDDNSDLLVCASEMQEDRLYFVAFKKNIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLN---------------AKCHANKKIVHYTSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRFCDASYGPSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKSKT----LPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICETTKG---AIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQSWLWSEGERMRRRTSLPILQHTYGINSLELKKKLASAAADSTEHVDLLLTRVKGISQRVDTMHLNDQDNLDAACTDQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDTDTISAPADPPPTSSYTISTRRRKSPSGANKPTVIATSLRRLVNPNANRSGLSTASGVYPTPELASCTEKKLRKPSANVFEAARHTIASTVRMTQTALEKKQAQTQGDKLNQIKALRRHHSRSVNVNSNSSEQESNVRHTRARSQPFRNNNNGVGGNTAMAALKPTSSCLPTGTGTAALLANNLNNNNDCGIGTSGSSNNNHNNNNNNSNLSNSLNNYNNNNNTTNNILASSGSSRTRSLALYSKRMELKHLRKAEQQQQQQVQQEQPLLPVEKQLLRQYATINESKIPVVSGGGGGAGSSATIPPTRGSAARTSHHHMTLRGRSRIRYQRPNAGETAPAAAQTQPCTVATARYYRDVSAIPTIGVFGGGPGGSSSTSASFNIATRSASATLDLNSNPLPKTTKLTSLNNNPTTTPPPSSNPADTSRLSGRGSAELQAIIEHGLVAGSAKRNKRSLSSTRLDKDKSDEYNTKLLRKTAAAAAAAATAASAVANSTSINATHATNASTTSSMNNNCKYNSCSSSNSGSFKLSRRLFGESGSSASTSASNSGIPTPTAPPSSSQWQQHLVRGVSRASSEKDRDRERQQQQQQQSLDHQQSNLKLRKKISY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00684-1", "uniprot_id": "CDC14_YEAST", "id": "Q00684-1", "name": "Tyrosine-protein phosphatase CDC14", "aln": "--------------------------------------MRRSVYLDNTIEFLRGRVYLGAYDY--TPEDTDELVFFTVEDAIFYNSFHLDFGPMNIGHLYRFAVIFHEILN---------------DPENANKAVVFYSSASTRQRANAACMLCCYMILVQAWTPHQVLQPLAQVDPP-FMPFRDAGYSNADFEITIQDVVYGVWRAKEKGLIDLHSFNLESYEKYEHVEFGDFNVLTP-DFIAFASPQEDHPKGYLATKSSHLNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNFVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTR-------------------------ISLKPSEAIGGLYPLISLEEYRLQKKKLKDDKRVAQNNIEGELRDLTMTP--------------------------------------------------------------------------------------------------------------------------------PSNGHGALSARNSSQPSTANNGSNS----FKSSAVPQTSPGQPRK-------------------------------------------GQNGSNTIEDINNNRNPTSHANRKVVIESNNSDDESMQDTNGTSNHYPKVSRKK----------------------------NDISSASSSRME----------DNEPSATNINNAADDTILRQLLPKNRRVTSGRRTTSAAGGIRKISGSIKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : ..: : * :: : *:.* ****:*: :**:. :: *: .* ::.:: . :: *** :: .* :: :*. . * . . : * **.:. . : :.: * . .: :. : * ::: *: :.** :*:.* **:* : * ::**..*: ..: :. : : :* .:** ::*** ::*. . * : *:.* **:* **: * * .*: .*. :************ **..::: : :* * *.::*: *** ::* **::: * : * . . . . . :*. : : : ", "identical_positions": 81, "similar_positions": 124, "identity": "7.3%" }, { "cls_id": "homologset.agr.SGD:S000001927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5Q2-1", "uniprot_id": "D4A5Q2_RAT", "id": "D4A5Q2-1", "name": "Structural maintenance of chromosomes protein", "aln": "MYVKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKERSAGELKEMQDKILKLQEVLSENEKKIKALNCEIEELEKRKDKETG--GILRSLEDAFAEAQRVNTKSQSAFDLKKKNLASEETKRKELEKNMAEDSKALAAKEKEVKKLTDGLHGLQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTGAKQAQMKLKHAQQELKNKQAEVRKMDSGYKKDQEAFEAVKKVKEKLETEMKKLNYEDNKEERLLEKHRQVSRDISNLKGTYEALLAKFPNLRFAYKDPEKNWNRNCVKGLVASLINVKD--NSTATALELVAGERLYNVVVDTEVTGKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPNNVHVALSLVDYKPELQKAMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELKDVQAELRTKEKELQALEEELAGLKNVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVNEAIKAYEGQIEIMAAEVAKNKESVNKAQNELMKQKEIISAQDNIIKDKCAEVAKHNLQNNDSQLKIKELDHSISKHKREADDAAAKVSKMLNDYDWINAEKHLFGQPNSAYDFKTNNPKEAGQRLQKLQEVKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILATIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQSQNGR-IPKEAKAKGKGPS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG48-1", "uniprot_id": "SMC2_MOUSE", "id": "Q8CG48-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MYVKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLRAEDTKERSAGELKEMQDKIVNLQEVLSENEKKIKALNCEIEELERRKDKETG--GKLKSLEDACAEAQRVNTKSQSAFDLKKKNLASEETKRKELQNSMAEDSKALAAKEKEVKKITDGLHGLQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMIACKNDISKAQTEAKQAQMKLKHAQQELKSKQAEVKKMDSGYKKDQDAFEAVKKAKEKLETEMKKLNYEENKEEKLLEKHRQLSRDINNLKGKHEALLAKFPNLQFAYKDPEKNWNRNSVKGLVASLINVKD--NSTATALEVVAGERLYNVVVDTEVTAKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVDYKPELQKGMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQEVKDVQDELRTKENELRALEEELAGLKNVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEELDALKKTIEESEETLKSTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVNEAIKAYEGQIEKMAAEVAKNKESVNKAQDELMKQKQIITAQDNIIKDKCAEVAKHNLQNNESQLKIKELDHSISKHKREADDAAAKVSKMLSDYDWINAEKHLFGQPNSAYDFKTNNPKEAGQRLQKLQEVKEKLGRNVNLRAMNVLTEAEERYNDLMKKKRIVENDKSKILATIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQSQAGK-IPKEAKSRGKEPN-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95347-1", "uniprot_id": "SMC2_HUMAN", "id": "O95347-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MHIKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEKRKDKETG--GILRSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASLISVKD--TSATTALELVAGERLYNVVVDTEVTGKKLLERGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVEYKPELQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQEMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQCQNGK-ISKEAKSKAKPPKGAHVEV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5K9-1", "uniprot_id": "B8A5K9_DANRE", "id": "B8A5K9-1", "name": "Structural maintenance of chromosomes protein", "aln": "MYIKSIVLEGFKSYAERTEINGFDPFFNAITGLNGSGKSNILDSICFLLGISNLSQVRATNLQDLVYKNGLAGITKATVSITFDNSNKKQSPLGFETHDEITITRQVVIGGRNKYLINGVNANNLRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILAMIEEAAGTRMYECKKISAQKTIEKKDAKLKEIQTILDEEITPAMEKLKEERASYLEYQKLMREIEHLSRLYVAYLFVCAEETKLKSNEELQEMQSSIAKLQENMKQNEAKVKELSAEIQELERRRDKEVG--GVLRTLEETLSEAQRVDTKAQSALDLKKQNLKDETKKRKELVKNMEEDKKVMSAKEAEVAKAVERLKAVKEEGQKDAEALEAAQQHFKAVSAGLSANEDGAEATLSGQMMTCKNDISKAETEAKQAQMKLKHAQQELKTKQAQVKKMDSGYKKDQDTFEAVNKCIEKLQAEMKKLNYEDGREECLLEQKRQFSREVIQLREAYESLMGQFPNLRFEYTDPERNWERSKVKGLVANLFTVTD--VSNATALEVVAGGRLYNVVVDNEVTGKKLLEKGELRRRYTIIPLNKISARTLNDNVVRTAKKLVGPDNVHTALSLVGYESELRKAMEYVFGTTLVCDSLDNAKKVAFDKGVSTKTVTLGGDVFDPQGTLTGGARAQTASVLSKLAEVKDIQDSLRNKEAELSAVESELSGLKGTAEKYRQLKQQLDLKTEEARILETKLQQSSFHKQQEELENLRKTIEECEDTLQKTKEVQKKAEEKYNVLENKMKNAAAEREKELKAAQQKLNQAKSKADAFSKRLKEKQQEADAVALELEELKREQAGYEQQIQAVDEALKAVQEQIDNMTTEVSANKEAVRVAQEKLSQQKEVIMGQEREIKGKSGEANRLREQNNDAQLKIKELEHNISKHKKDSADATAKVARMLAENDWISSEKHLFGQPNTAYDFKTNNPKEAGQRLKRLEETKDKLERNVNRRAMNMLSEAEERYNDLKKKKRIVENDKAKILETIEELDQKKNEALNVAWQKVNKDFGSIFSTLLPGANARLAPPEGCGVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILAMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFVVVSLKDGMFTNANVLFKTKFVDGISTVTRTAQTHEGKVLAQRTQEKAKDKRQRQILAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38989-1", "uniprot_id": "SMC2_YEAST", "id": "P38989-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MKVEELIIDGFKSYATRTVITDWDPQFNAITGLNGSGKSNILDAICFVLGIASMSTVRASSLQDLIYKRGQAGVTKASVTIVFDNTDKSNSPIGFTNSPQISVTRQVVLGGTSKYLINGHRAPQQSVLQLFQSVQLNINNPNFLIMQGKITKVLNMKPSEILSLIEEAAGTKMFEDRREKAERTMSKKETKLQENRTLLTEEIEPKLEKLRNEKRMFLEFQSTQTDLEKTERIVVSYEYYNIKHKHTSIRETLENGETRMKMLNEFVKKTSEEIDSLNEDVEEIKLQKEKELHKEGTISKLENKENGLLNEISRLKTSLSIKVENLNDTTEKSKALESEIASSSAKLIEKKSAYANTEKDYKMVQEQLSKQRDLYKRKEELVSTLTTGISSTG-AADGGYNAQLAKAKTELNEVSLAIKKSSMKMELLKKELLTIEPKLKEATKDNELNVKHVKQCQETCDKLRARLVEYGFDPSRIKDLKQREDKLKSHYYQTCKNSEYLKRRVTNLEFNYTKPYPNFEASFVHGVVGQLFQIDNDNIRYATALQTCAGGRLFNVVVQDSQTATQLLERGRLRKRVTIIPLDKIYTRPISSQVLDLAKKIA-PGKVELAINLIRFDESITKAMEFIFGNSLICEDPETAKKITFHPKIRARSITLQGDVYDPEGTLSGGSRNTSESLLVDIQKYNQIQKQIETIQADLNHVTEELQTQYATSQKTKTIQSDLNLSLHKLDLAKRNLDANPSSQIIARNEEILRDIGECENEIKTKQMSLKKCQEEVSTIEKDMKEYDSDKGSKLNELKKELKLLAKELEEQESESERKYDLFQNLELETEQLSSELDSNKTLLHNHLKSIESLKLENSDLEGKIRGVEDDLVTVQTELNEEKKRLMDIDDELNELETLIKKKQDEKKSSELELQKLVHDLNKYKSNTNNMEKIIEDLRQKHEFLEDFDLVRNIVKQNEGIDLDTYR---ERSKQLNEKFQELRKKVNPNIMNMIENVEKKEAALKTMIKTIEKDKMKIQETISKLNEYKRETLVKTWEKVTLDFGNIFADLLPNSFAKLVPCEGKDVTQGLEVKVKLGNIWKESLIELSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTRFKGSQFIVVSLKEGMFANANRVFRTRFQDGTSVVSIM----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::.::::****** ** :..:** *****************:***:***:.:* ***:.****:**.* **:***:*:*.***::*.:**:** :*::*****:** .****** .* : * :** ** **:***:******:*********.***::*******:*:* :: *::*:.**::**:* :*:* *** * ::**::*: :**:*. ::*: .*: ::* : :..: *:: : : *:* :.:.. ::. *. :::*:: :::** * : .**: . :: ::::.:* :** * * * ..: ... : *: : . : ::* .*: : :: ..::::*:*:. .*:. .*: .*.::.:.. *::.**:: ::** . :.:::: .. . : . .: :. :**.:.: : .:: .: : * ::. :.. . . * * :..**.* *..* *:: . *:*:*..*: : : :***: ** **:****: . *..:***:*.*::* *****:** :* : :.: *:::. *.:*. *:.*: :. .: *.**::**.:::*:. :.***::*. : ::::** ***:**.***:**:* : *:* .: : :::* .:. : :* : .** .::* : ::.: ::. .: : : :*: .. : . : : : * *.*: ::..: :*.:*: ..:*:.**: ::: :*: :::*. .: : ... :.* : : : ** *:*. * . : :. ::::: : : . : :: :: : .* :: ::*: : : :: : . :::.::*::::* *.:.*:* :: : : : . :::. : . : .:. :. : :* ::*:* ::* ::** . **:: :.*:: * . : :*:** ** **..*:: *.::* :*:**. ***.**: ***.: * *.* ** * :***.** *** ***.* *********:*****:::* *:***:*******************::::*:*. ***:*****:*** *** :*:*:* ** *.*: ", "identical_positions": 373, "similar_positions": 462, "identity": "31.01%" }, { "cls_id": "homologset.agr.SGD:S000001929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M9I5-1", "uniprot_id": "QCR6_RAT", "id": "Q5M9I5-1", "name": "Cytochrome b-c1 complex subunit 6, mitochondrial", "aln": "MGL------------------------------------------------EDERKMLTGSGDPKEEEEEE--LVDPLTTVREHCEQLEKCVKARERLESCDRRVSSRSQ--------TEEDCTEELFDFLHARDHCVAHKLFKSLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P99028-1", "uniprot_id": "QCR6_MOUSE", "id": "P99028-1", "name": "Cytochrome b-c1 complex subunit 6, mitochondrial", "aln": "MGL------------------------------------------------EDERKMLTGSGDPKEEEEEE--LVDPLTTVREHCEQLEKCVKARERLELCDNRVSSRSQ--------TEEDCTEELFDFLHARDHCVAHKLFKNLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07919-1", "uniprot_id": "QCR6_HUMAN", "id": "P07919-1", "name": "Cytochrome b-c1 complex subunit 6, mitochondrial", "aln": "MGL------------------------------------------------EDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELCDERVSSRSH--------TEEDCTEELFDFLHARDHCVAHKLFNNLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A096LP55-1", "uniprot_id": "QCR6L_HUMAN", "id": "A0A096LP55-1", "name": "Cytochrome b-c1 complex subunit 6-like, mitochondrial", "aln": "MGL------------------------------------------------EDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELYDEHVSSRSH--------TEEDCTEELFDFLHAKDHCVAHKLFNNLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00127-1", "uniprot_id": "QCR6_YEAST", "id": "P00127-1", "name": "Cytochrome b-c1 complex subunit 6, mitochondrial", "aln": "MGMLELVGEYWEQLKITVVPVVAAAEDDDNEQHEEKAAEGEEKEEENGDEDEDEDEDEDDDDDDDEDEEEEEEVTDQLEDLREHFKNTEEGKALVHHYEECAERVKIQQQQPGYADLEHKEDCVEEFFHLQHYLDTATAPRLFDKLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A8Y535-1", "uniprot_id": "A8Y535_DROME", "id": "A8Y535-1", "name": "Cytochrome b-c1 complex subunit 6", "aln": "MAF------------------------------------------------RNWFSLPAVRADDEED------LVDPQAVLREKCQAKGHIESLYNKYQECNDRVNGRSK--------TTETCIEELFDYVAELDHCVSHSLFTKLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .: . * .*: :.* :**: : . .: : :*. :.: * * **:*. * ..: ** .**", "identical_positions": 17, "similar_positions": 27, "identity": "11.56%" }, { "cls_id": "homologset.agr.SGD:S000001933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A510-1", "uniprot_id": "D4A510_RAT", "id": "D4A510-1", "name": "", "aln": "----------------------------MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIVKRHQGTISEDKSNASHVVYPAPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVSDDKSPVSRRKKISAKTLTDEVNSPDADRRDKKG-GNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQDDESMETTGKDEDENSTGNKGEQTKSADLHEDNVTEQTHHIIVPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKPPQGRQVDADTKAGRKGKELDDLVPEAAKGKPELQGSASQQMLNFPDKGKEKPADMQNFGLRTDMYTKKNIPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTASDEPERIEESGTEEARA-ESQAADEKKEPKEPREGGGAVEEEAKEEISEAPKKDEEKGKEADSEKESEKSDGDPIVDPEKDKEPTEGQEEGLKEVAEPEGERKAKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMQQQPPPPPPPPPPPALPPGSQPIPPTGAAAPATVHGLAVAPASVASAPPGGGAPPGTLGPSEQIGQAGTTAGPQQPQQAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGLPLPPP-AAPSIIPFGSLADSISINLPPP-NLHG-HHHLPFAPGTIPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGSLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDG5-1", "uniprot_id": "SMRC2_MOUSE", "id": "Q6PDG5-1", "name": "SWI/SNF complex subunit SMARCC2", "aln": "----------------------------MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIVKRHQGTISEDKSNASHVVYPVPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVSDDKSPVSRRKKISAKTLTDEVNSPDSDRRDKKG-GNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQDDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKPPQ-------------------------------QSSASQQMLNFPEKGKEKPADMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTASDEPERIEESGTEEARP-EGQAADEKKEPKEPREGGGAVEEEAKEEISEVPKKDEEKGKEGDSEKESEKSDGDPIVDPEKDKEPTEGQEEVLKEVAEPEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQQP-----PTLPPGSQPIPPTGAAGPPTVHGLAVPPAAVASAPPGSGAPPGSLGPSEQIGQAGTTAGPQQPQQAGAPQPGAVPPGVPPPGPHGPSPFPNQPTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPP-AAPSVIPFGSLADSISINLPPPPNLHGHHHHLPFAPGTIPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAQ2-1", "uniprot_id": "SMRC2_HUMAN", "id": "Q8TAQ2-1", "name": "SWI/SNF complex subunit SMARCC2", "aln": "----------------------------MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKG-GNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKTPQ-------------------------------QTSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPERIEESGNDEARV-EGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPP-----PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5E9-1", "uniprot_id": "A0A8M9Q5E9_DANRE", "id": "A0A8M9Q5E9-1", "name": "", "aln": "----------------------------MAVRKKDGGPNVKYFEASDTVSQFDNVRVWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGRHVSNPPLTKLPVKCFLDFKAGGALCHILAAAYKFKSDQGWRRFDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPVIYLSSEIEPKLLGKLKDIIKRHQGSVTEDKLSSSHVVVPIPASLEDEEWVRPVMKRDKQMLLHWGYWPDSYDTWISASEVEAAVEDPPAAEKPRKVHAKWILDLDQFNEWMNEEDYEVGEGG---PRRKRISAKTLTDEVSAPD-ERRDKKP-SGAKKRKRSPSPSPTPPPQESKKKNTKKGPTTPYTKSKRGQREEEQEDLTKELDEPSPVPAVEEATLPKTV-TKKDSDSTPVKGGTMTDLDEQEDESMETVGKEEEEGSPSVKGEPVKGSDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDSESRPTPMGPPPTSHFHVLADTPSSLVPLQPKASQ--------------------------------TSSSQQMLSFPEKVKDKPADLQNFGLRTDVYSKKSGPAKNKNAASATREWTDQETLLLLEGLEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSSASLGPLAYQPVPFSQAGNPVMSTVAFLASVVDPRVASAAAKSALEEFSRMKEEVPAALVEAHVRRVEEAARASGRQDPLYGLEGSGIAGTGLEDSDKPSDDGGEENKSSEGQPSQEKRDSKESKDG----ASEEEEKQGENGKKEEERAREVETERETEKTDS-EMADGEKEKERKEGSEEAQRD-GETEGEKKAKVERDVGEGNLATAAASALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQSFHMEQLKYAEMRARQQHFQQIQHQHHSNQ---------PGSQ-----SATAPPVPH----QPVATASAPP--------------------------PTPSPAPLTATNTHSEAPPPPAAHSSPPN-----NTQAGAAHDSSTTPLAG-----------------------------------------------------------------DSLYP-------------------------------------------------------------TAPVPPSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97496-1", "uniprot_id": "SMRC1_MOUSE", "id": "P97496-1", "name": "SWI/SNF complex subunit SMARCC1", "aln": "MAATAGGG-PGAAAGAVGAGGAAAASGLAVYRRKDGGPASKFWESPDTVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGTLCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYPSSQEDEEWLRPVMRRDKQVLVHWGFYPDSYDTWVHSNDVDAEIEDAPIPEKPWKVHVKWILDTDVFNEWMNEEDYEVDENRKPVSFRQRISTKNE-EPVRSPE--RRDRKASANSRKRKPSPSP-PPPTATESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKNVNPKKDSENTPVKGGTVADLDEQDEEAVTTGGKEDEDPS---KGDPSRSVDPGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQ--------------------------------VPAAQQMLNFPEKNKEKPIDLQNFGLRTDIYSKKT-LAKSK-GASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLE--GSEEEKM-ETDPDGQQPEK----------AENKVENESDEGDKIQDRENEKNTEKEQDSDVSEDVKPEEKENEENKELTDTCKERESDAG--KKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQQHGQTPQQ-----AHQHTGGPGMAPLGATGHPGMMPHQQPPPYPLMHHQMPP--------------------PHPPQPGQIPGPGSMMPGQPMPGRMIPAVAAN---IHPTGSGPTP-PGMPPMPGN-----------------------------------------------------ILGPRVPLTAPNGMYP---------------------------------------PPPQQQQPPPP-ADGVPPPPAPGPPASATP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92922-1", "uniprot_id": "SMRC1_HUMAN", "id": "Q92922-1", "name": "SWI/SNF complex subunit SMARCC1", "aln": "MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRISTKNE-EPVRSPE--RRDRKASANARKRKHSPSP-PPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQ--------------------------------VPAAQQMLNFPEKNKEKPVDLQNFGLRTDIYSKKT-LAKSK-GASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLE--GAEEEKM-EADPDGQQPEK----------AENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKELTDTCKERESDTG--KKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQ-HGQNPQQ-----AHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPP--------------------PHPPQPGQIPGPGSMMPGQHMPGRMIPTVAAN---IHPSGSGPTP-PGMPPMPGN-----------------------------------------------------ILGPRVPLTAPNGMYP---------------------------------------PPPQQQPPPPPPADGVPPPPAPGPPASAAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43609-1", "uniprot_id": "RSC8_YEAST", "id": "P43609-1", "name": "Chromatin structure-remodeling complex protein RSC8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDTEKDKDVPMVDSHEATEEPPTTSTNTPSFPHLAQEQAKEESATLGAEVAHKKINYEQEAQKLEEK-------------------ALRFLAKQTHPVIIPSFASWFDISKIHEIEKRSNPDFFNDSSRFKTPKAYKDTRNFIINTYRLSPYEYLTITAVRRNVAMDVASIVKIHAFLEKWGLINYQIDPRTKPSLIGPSFTGHFQVVLDTPQGLKPFLP----------------------------------------ENVIKQEVEGGDGAEPQVKKEFPVNLTIKKNVYDSAQDFNALQDESRNSRQIHKVYICHTCGNESINVRYHN---------------------LRARDTNLCSRCFQEGHFGAN----FQSSDFIR-------LENNGNSVKKNWSDQEMLLLLEGIEMYEDQWEKIADHVG-------------------------------------------------------------------GHKRVEDCIEKFLSLPIEDNYIREVVGSTLNGKGGDSRDGSVSG--------SKLMECVNDAVQTLLQGDDKLGKVSDKSREISEKYIEESQAIIQELVKLTMEKLESKFTKLCDLETQLEMEKLKYVKESEKMLNDRLSLSKQILDLNKSLEELNVSKKLVLISEQVD-----------------SGIQLVE-----------------------------------------KDQEGDDEDGNTATGHGVKRVGKEGEEVGEG-----DSIAKLQPQVYKPWSL--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ::: : .*.. : :*: . : ..:.:.: . . . : ::*: * :::**: :*:**:*:*** . :* **:*: *:***...: ***: * ***:*:****.* **** ** ***:: **.:::::*****:***:***:*..::* :**. * **:*: ***..* *: ::::. : : . : : .:: **. . : : * :.. : : . :: :* * *. .:.* . .:* *. :.: *: . .::. :::* . : :* : : :: * * .* : * . :. : : . . :* . : . *. .: *::.:: .: :::: **: *:*** *: :: :*** :: *: : :::* :* : : *. : . : :: . : . . . . ", "identical_positions": 102, "similar_positions": 180, "identity": "7.95%" }, { "cls_id": "homologset.agr.SGD:S000001934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7M6-1", "uniprot_id": "A0A0G2K7M6_RAT", "id": "A0A0G2K7M6-1", "name": "Proliferation-associated SNF2-like protein", "aln": "MPAERPASSSGPLAPEMAEQTEPAVITPAMLEEEEQLEAEGLEKERKMLEEARKSWDRESTEIRYRR----LQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKVTEGKNLIDGNEENTVMKKKRGREDESYNISEVMSKEEILSVAKKHK-DNEDENSSTTNLCVEDLQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGNR--QERRKLVKNIHKRQGTLQIHPVVITSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL-------SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPP-KREVVVYAPLCNKQEIFYTAIVN-RTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVKRERTVVEGNIPIESEVNLKLQNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRCHKVLVFSQMTSMLDILMDYCHLRNFTFSRLDGSMSYSEREKNIYSFN-TDPEVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKEKTGIFKILENSEDSSAECLF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60848-1", "uniprot_id": "HELLS_MOUSE", "id": "Q60848-1", "name": "Lymphocyte-specific helicase", "aln": "----------------MAEQTEPAVITPAMLEEEEQLEAAGLEKERKMLEEAQKSWDRESTEIRYRR----LQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKLTEGKSLVDGNGEKPVMKKKRGREDESYNISEVMSKEEILSVAKKHK-DNEDESSSTTSLCVEDIQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGTR--EDRRKLVKNIHKRQGTLQIHPVVVTSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL-------SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPP-KREVVVYAPLCNKQEIFYTAIVN-RTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVNRERTVVEGNIPIESEVNLKLRNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLVFSQMTSMLDILMDYCHLRNFIFSRLDGSMSYSEREKNIYSFN-TDPDVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKGKTGIFKILENSEDSSAECLF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRZ9-1", "uniprot_id": "HELLS_HUMAN", "id": "Q9NRZ9-1", "name": "Lymphoid-specific helicase", "aln": "MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRR----LQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQ--EERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL-------SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPP-KREVVVYAPLSKKQEIFYTAIVN-RTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFN-TDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43610-1", "uniprot_id": "IRC5_YEAST", "id": "P43610-1", "name": "Uncharacterized ATP-dependent helicase IRC5", "aln": "-----MSRCSNAALMTVVEDAVGARVAARTRNMSNGVNYREKEVNDLTADISDSDSDLDSEDNKHGKGDNDTAPIWLQDDVHSDEDIQLDSEDDSDTEAVQAQVVDKLAKDTKSEQKSLDDELSEMDTKTVSLKLKKLNEFVRQSQVYSSIIADTLLHRSNEVANANTKDNSNSDDEEHSSKKRKTKKKSITDFFKKQKKNEDTTTQNGAPDDAAIKQPRLLKNCILKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHG---GTGIVITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISN-KKLQNMMMQLRQIIDSTFLFYFPY--LHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQMGKFNNLKKLALNEGSFLKANKAGVNVTNKDLVQELSMLLMSDESNIGFENGGQKENKATEGQLTDKEVEELTNRSLEAYKANRVVDLPHVKLFETTSGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 263, "similar_positions": 296, "identity": "30.44%" }, { "cls_id": "homologset.agr.SGD:S000001936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q922D4-1", "uniprot_id": "PP6R3_MOUSE", "id": "Q922D4-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "aln": "-MFWKFDLHS-SSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQVQNST-------EPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIR-LISSLLQTNTSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFEN-------------------AENGTIT---DQDSTGDNLLLKHLFQKCQLIER----------------ILEAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIK----DLPDEVRERWETFCTNSLGETNKRNTVDLA-------------------------------FSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDIN-FTLNTN--ESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS-SSGSTDSEESTDSEEEDGAKQDLFESSSA-------------NTEDKMEVDLNEPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGW------ASFSEFTSSLSTKESLRSNSPVEMETSTES-VDPLTPG---AAA--------LATQPEAPGSMAME-----ASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK----------SEEEKLSTSQDAACK-------DAEET----------------PEPAEAKCTAP----LTPSSSPEQRTDQPSMPSDPSVNGPV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAH5-1", "uniprot_id": "F1MAH5_RAT", "id": "F1MAH5-1", "name": "", "aln": "-MFWKFDLHS-SSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQVQNST-------EPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIR-LISSLLQTNTSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFEN-------------------AENGTIT---DQDSAGDNLLLKHLFQKCQLIER----------------ILDAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIK----GLPDGVRERWEAFCTDSLGEANKRNTADLVTTCHIHSSSDDEID-F-KDTGFSQDSSLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDIN-FTLNTN--ESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS-SSGSTDSEESTDSEEEDGAKQDLFESSSA-------------NTEDKMEVDLNEPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGW------ASFSEFTSSLSTKESLRSNSPVEMETSTEP-VGPLTPG---AAA--------LASQPEAPGSVAME-----ASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK----------SEEEKLSTSQDAACK-------DTEET----------------PESAEAKCTAP----RTPNSSPEQRTDQPSMPGDTSVNGPV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AWD3-1", "uniprot_id": "A0A8M3AWD3_DANRE", "id": "A0A8M3AWD3-1", "name": "", "aln": "-MFWKFDLHS-TSHIDTLLEKDDVTLTEVMDEEDVLQECKAQNHKLVDFLVRPQCMEDLVVYITQEPNDDVEEKIKYKYPNISCELLTSDVGQINDRLGEDESLLMKLYSFLQNEPPLNPLLASFFSKVLSILIGRKPEQ-----------IVEFLRKREDFVDLMIKHIGTSAIMDLLLRMLTCIEPQQLRQDVLNWLNEEKVIQRLVDMVQPSQDEDRHSNASQSLCEIIRLSRDQMFQVQGSS-------EPDPLLATLEKQETVEQLLSNIFDKEKNESAIVSVIQILLTLFETRRP------------AFEGHLEICPPGMNHPSFSVNQSILDAVRPRLKDFHQLLLEPPKKTVLNTTWGVLDPPVGNTRLNVVR-LVTSLLQTNTHIINQELIALNTLGVILDMYFKYLWNNFLHTQVEICTAMVLAMPSTQ-------------------SESPEINRENDQEPIRENILIKHLFQKCQLIQR----------------ILDAWGSNDKEQTEGGRRRGYMGHLTRIANSIVHNSDKGPNGSQIQQLISGLSIELPEEDRERWEAFTSGQLADTNKKNTVDLVNTHHIHSSSDDEVD-F-KDSGFHQDSSLQQAFSDYQMQQMTSNFIEQFGFNDEEFADQDDVGDIPFDRISDIN-FSLNTN--ESANVALFEACCKEKIQQFEDAGSDEEDIWDEKDVTFAPEAPRRPRSSGSTDSEESTDSEEEDG-KRDPFESTNA-------------TSDDRMEVDSGDGTVWTANFDDIPMDTGSSTAPSAPVSNSTASVPESTGWSSPNASGDGETGW------ADFSSFTP-VSPKDPLRCNSPVAMETSIET-VDPLGVN---APMQQENTDQWLPNETTPTSPRGKT-----GDASDPEEEPVSDRITETVTNGSMKETVSLTVDAKTETAVFKR----VLKSYREEEKQSTSEDASAKLFVAESGDAEKSNCPSSNCQK--PGLKHLEKAKSPCEALNGPLEDAADMDEAKSEQCTANPEAAVNGPA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TSI3-1", "uniprot_id": "PP6R1_MOUSE", "id": "Q7TSI3-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "aln": "-MFWKFDLHT-SSHLDTLLEKEDLSLPELLDEEDVLQECKVVNRKLLDFLLQPSHLQAMVAWVTQEPPASGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSGDSLNPLLASFFSKVMGILINRKTDQ-----------LVSFLRKKDDFVDLLLRHIGTSAIMDLLLRLLTCVERPQLRQDVFNWLNEEKIVQRLIEQIHPSKDDNQHSNASQSLCDIIRLSREQMIQGQDSP-------EPDQLLATLEKQETIEQLLSNMFEGEQCQSVIVSGIQVLLTLLEPRRPRSDSVTMNNFFSSVDGQLELLAQGALDDALSS-MGALHALRPRLDRFHQLLLEPPKLEPLQMTWGSLAPPLGNTRLHVVK-LLASALSANAAALTQELLVLDVPNTLLDLFFHYVFNNFLHAQVEVCVSAMLSSGPPP-------------------DSS--------SETPVPNPIVKHLLQHCRLVER----------------ILASWEENDRVQSGGGPRKGYMGHLTRVANAVVQNAEQGPNAEQLGQLLK----ELPEEQQQRWEAFVSGPLAETNKKNTVDLVNTHHLHSSSDDEDDRL-KEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANIT-FSLNADD-ENPNANLLEICYKDRIQQFDD---EEEEE--EEGQGSAESDGEYGAWQGSQPVRASQASQPPGVRSGGSTDSEEE-------------DEEEDEEED--EGAEQAACGRTSPSSFPSPSTQPPGPS----------WTATFDTVPMDAPTG------PPVSKEADMSS--------IQIPS--------SPPAHG---SPQ--------LRSQ-DPTHPSAPQ-----EVTDSSKVAEPLAPCQALVSVADVQATLHGMRSAPSSLDSAT-----------RDPSTSVPDFKAHQ--------SPQT----------------MEGKRSPEHLGLPQSQSALEMP-----NGSTPGGPISSGSQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPN7-1", "uniprot_id": "PP6R1_HUMAN", "id": "Q9UPN7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "aln": "-MFWKFDLHT-SSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAWVTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLLASFFSKVMGILINRKTDQ-----------LVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQDVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSP-------EPDQLLATLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLELLAQGALESTVSS-VGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVK-LLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPP-------------------DSS--------PETPIQNPVVKHLLQQCRLVER----------------ILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEKGPNAEQLRQLLK----ELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRL-KEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANIT-FSLNADD-ENPNANLLEICYKDRIQQFDD---DEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDE-------------EEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS----------WTATFDPVPTDAPTS------PRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARD---ALQ--------LRSQ-DPTPPSAPQ-----EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT-----------RDPSTSVPASGAHQ--------PPQT----------------TEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGSQ-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3Q2-1", "uniprot_id": "PP6R2_MOUSE", "id": "Q8R3Q2-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 2", "aln": "-MFWKFDLNT-TSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVNLITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDRLGEDESLLNLLYDFLDQEPPLNPLLASFFSKTIGNLIARKTEQ-----------VIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKIIQRLVALIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-------EPDPLLITLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVG------------TEGLVDSFSQGLER-SHSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGAR-LMAALLHTNTPGINQELCRLNTMDLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREEQAEASGSDGKVEPLQGSGDGNGKLETTPSITSPPENTMVTHLFQKCCLVQR----------------ILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISEVIR----GLPADCRGRWESFVEETLMETNRRNTVDLA-------------------------------FSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEIN-FNIEADE-DSPSAALFEACCSDRIQPFDD--DEEEDIWEDDETRCAARVMARARFGAPHVSDNYSKNALEHGGQDRKTGSAVARNVPGLAAPSSPTQKEGPRSESDSAGTTWTAVFDEPVNPLSATPGAARDVG---------SSAWAAGPSVVEEKGW------AKFTDFQPFCCSETGPRCSSPVDMDHSNAEGGQSPGPEKTFGPTSPCAWNVCVTRKAPLVASDSSS-----SGGSDSEDDEKAAGAVEAVCTGHTGKVSPPPRTAEAAVGRAECPDSTVLAPACPAPSEVTISPAVATIAPSKAGSPTATIVVSSS-----VAAAVPPGPIVAVTTAAPAIVATLGTMTKDRKADALPEGAALNGPV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M9PEH8-1", "uniprot_id": "M9PEH8_DROME", "id": "M9PEH8-1", "name": "", "aln": "-MFWDKGYAP-SANIEALLEKENSTLEEFLDEEDILQECKTQKKNLVNYFTRPEVIRRLVELITTEPSEDVPMSKRFRYANMSCEILTLGLPSLDEKLLNDAETLQLLYSYLEKEPPLNPLLSSFFSKTFSMLFTKKPEQDWFLYQHMCLQLLEYIKSQKTFLDFICKHFDTPVIPDLIMQMMKDIEGGRLKRNLFEWLTEDKIVERLIAILRNPQETDKHANVADFFCDLINQGRLMRQTEQENDSFEPAFDGSNPILKTIEFADTIEALLNVILEPNAQESAILSGISVVLTLIKPITFTDE---------PNSDRQRLLQKREREIHQEVQETVITVMAPRLQEFVHILKNPPAKPTLETTAAVLTPPFGKTRLQVCR-VFTALLETKHETIQQAICATEYFSLLLDFFKQYCWNNFLHTEMEKALYVVFYNELSN-------NNTASTEVTDYFTADCLINAFLKVGTEESEVEMKNALNDAKRAEGGKDEEGGDIEIEVAAAQEVAAQTPDERQTAAEENQEHEEHMSQVEAAAEATASEDAEPKAQDNEVKN---SEVDGESPTDQQESEATLNDLDKTKTVPSPPPSEMQSHLIVNCHLISKLVDLWQHNAQAQSAEKGRRLGYMGHLIKILRHITNCISESEHIGDLITSSLSDEDEVKLWQSL-IDAETGEFSLAVKQQTKLLADCNPHEENQYNDGSNDYTGEINAWN--VGNLPYREVDCSELNNTLQDIFFAIDQNRFQFG--------RNIDDEDDDDDEHGDHSGGGDGHGHGMFTKNSNTLNNLADPWDIQFAVLSSAPTQVNTGTANWGTDFNSDNFADFDAHFSTFGSDLGMPISAPPGEEEEEDSSPAPES--ATQVNPEEERQPAESIGLAVGKGVQ-----DNLACTDDQQAEYDNNANVEKAISDKLAESSVVETAAIVTRLQSVLLDGEDDYEDDEGMWTKPLGADRPSETEQITPISNGPDSKVNE--LGLPFSNHANDISSNNVDGHEANITTEQQKLAAAAKTNNVEIATTTT----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43612-1", "uniprot_id": "SA155_YEAST", "id": "P43612-1", "name": "SIT4-associating protein SAP155", "aln": "MSFWPFGQNLNHSNINKILDEYFHVLHELERINPSVGKAIPAIFNNVQERGTSDSLDSIPEEYSHGDEVKTARGDQKSRFEKDDQQERYEKEEEERSMNSSESSTTSFSSGSTSKTDLDEEDISNATAPMMVTTKNLDNSFIERMLVETELLNELSRQNKTLLDFICFGFFFDKKTNKKVNNMEYLVDQLMECISKIKTATTVDLNNLIDYQEQQQLDDSSQEDVYVESDTEQEEEKEDDNNSNNK-------KRRKRGSSSFGNDDINNNDDDDDANEDDESAYLTKATIISEIFSLDIWLISES-----LVKNQSYLNKIWSIINQPNFNSENSPLVPIFLKINQNLLLTRQDQYLNFIRTERSFVDDMLKHVDISLLMDFFLKIISTDKIESPTGIIELVYDQNLISKCLSFLNNKESPADIQACVGDFLKALIAISAN-----------APLDDISIGPNSLTRQLASPESIAKLVDIMINQRGAALN-------------TTVSIVIELIRKNNSDYDQVNLLTTTIKTHPPSNRDPIYLGYLLRKFSNHLSDFFQIILDIENDANIPLHENQLHEKFKPLGFERFKVVELIAELLHCSNMGLMNSKRAERIARRRDKVRSQLSHHLQDALNDLSIEEKEQLKTKHSPTRDTDHDLKNNNGKIDNDNNDNDDESDYGDEIDESFEIPYINMKQNIKLRTDPTVGDLFKIKLYDTRIVSKIMELFLTHPWNNFWHNVIFDIIQQIFN----------GRMDFSYNSFLVLSLFNLKSSYQFMTDIVISDEKGTDVSRFSPVIRDPNFDFKITTDFILRGYQDSYKFYELRKMNLGYMGHIVLIAEEVVKFSKLYKVELISPDIQVILQTEEWQYYSEEVLNETRMMYSKILGGGSYIDDGNGNIIPQLPDNTTVLTPNGDASNNNEILDSDTGSSNGTSGGGQLINVESLEEQLSLSTESDLHNKLREMLINRAQEDVDNKNTENGVFILGPPEDKNSNSNINNTNHNSNNSNNNDNNDNNDNDNDNTRNYNEDADNDNDYDHE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . :::: :*:. * *. : : :. : :: : : . : . : . . : . . : . . *: * : : . :. : :.. ::. : : : :. : : . ::.*: . : : : .: . . . . : : :: . : :* :: :: ::. .. . : : : : : : . : . :. : .. : :. : ::. : *: ::: . .: . : . : . . : . :. . . : : * : : : :. : : . .. . . .: . . . .: : .: . : . . . . . . ", "identical_positions": 11, "similar_positions": 155, "identity": "1.05%" }, { "cls_id": "homologset.agr.SGD:S000001937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61712-1", "uniprot_id": "DNJC1_MOUSE", "id": "Q61712-1", "name": "DnaJ homolog subfamily C member 1", "aln": "-------------MWVPGFGSARLPQRRRSGLE----SSSVRPLWLLLLFLLAAVRPVRAWESGDLELFDLVEEVQ------LNFYEFLGVQ--QDASSADIRKAYRKLSLTLHPDKNKDENAETQFRQLVAIYEVLKDDERRQRYDDVLINGLP--DWRQPVFYYRRVRKMSNAELALLLFIILTVGHYAVVWSIYLEKQLDELLGRKKRERKKKTGSKSVDAAKLGASEKNERLLIKPQWHDLLPCKLGIWFCLTLKALPHLIQDAGQFYAKYKETKLKEKEDALARIEIETLQKQKKVKVKKPKPEFPVYMPLENTYIQSYDHG---TSIEEIEEQMDDWLENRKRTQKRQAPEWTEEDLSQLTRSMVKFPGGTPGRWDKIAHELGRSVTDVTTKAKELKDSVTSSPGMTR--LSELKSNGQNSRPIKIATALPDDIITQREDSAGAMEDEE--HEAAEGEQESATTEARPRRRKSARAAEAVTRVEPEEKLRGKRQKDFDISEQNDSSDEEKQRKERTRAAEEAWTQSQQKLLELALQQYPKGASDRWDKIAKCVPSKSKEDCIARYKLLVELVQKKKQAKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVX1-1", "uniprot_id": "F1LVX1_RAT", "id": "F1LVX1-1", "name": "DnaJ homolog subfamily C member 1", "aln": "MAWLRTALSESSNMWVPGFGPARLP--RRPGLV----SSSMRPLWPLLLFLLVAVRPVRAWESGDLELFDLVEEVQ------LNFYEFLGVQ--QDASSADIRKAYRKLSLTLHPDKNKDENAETQFRQLVAIYEVLKDDERRQRYDDILINGLP--DWRQPVFYYRRVRKMSNAELALLLFIILTVGHYAVVWSIYLEKQLDELLSRKKREKKRKTGSKSVDAAKPGASERNERLLIKPQWHDLLPCKLGIWFCLTLKALPHLIQDAGQFYAKYKETKLKEKEDALARVELETLHKQKKAKVKKPKPEFPVYTPLENTYIQSYDHG---TSIEEIEEQMDDWLENRNRTQKKQAPEWTEEDLSQLTRSMVKFPGGTPGRWEKIAHELGRSVTDVTTKAKELKDSVTSSPGMTR--LSELKSNVQNSRPLKIATALPDDIITQREDSAGAIEEEEEEQETAEGDQETVTSEARPRRRKSAKVAEVVTRVEPEEKLRGKRQKDFDISEQNDSSDEERPRKERSRAAEDAWTQSQQKLLELALQQYPKGASDRWDKIAKCVPSKSKEDCIARYKLLVELVQKKKQAKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KC8-1", "uniprot_id": "DNJC1_HUMAN", "id": "Q96KC8-1", "name": "DnaJ homolog subfamily C member 1", "aln": "-------------MTAPCSQPAQLPGRRQLGLVPFPPPPPRTPLLWLLLLLLAAVAPARGWESGDLELFDLVEEVQ------LNFYQFLGVQ--QDASSADIRKAYRKLSLTLHPDKNKDENAETQFRQLVAIYEVLKDDERRQRYDDILINGLP--DWRQPVFYYRRVRKMSNAELALLLFIILTVGHYAVVWSIYLEKQLDELLSRKKREKKKKTGSKSVDVSKLGASEKNERLLMKPQWHDLLPCKLGIWFCLTLKALPHLIQDAGQFYAKYKETRLKEKEDALTRTELETLQKQK--KVKKPKPEFPVYTPLETTYIQSYDHG---TSIEEIEEQMDDWLENRNRTQKKQAPEWTEEDLSQLTRSMVKFPGGTPGRWEKIAHELGRSVTDVTTKAKQLKDSVTCSPGMVR--LSELKSTVQNSRPIKTATTLPDDMITQREDAEGVAAEEE--QEGDSGEQETGATDARPRRRKPARLLEATAKPEPEEKSRAKRQKDFDIAEQNESSDEESLRKERARSAEEPWTQNQQKLLELALQQYPRGSSDRWDKIARCVPSKSKEDCIARYKLLVELVQKKKQAKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWL4-1", "uniprot_id": "Q9VWL4_DROME", "id": "Q9VWL4-1", "name": "DnaJ homolog subfamily C member 1", "aln": "--------------------------------------MMMRPELTLAGLLLLCATGASAWHSEELEIFDLVEEVN------RNFYEFMGIN--QTATGAEVKRAFRTLSIVLHPDKNPAEDANIQFRNLVSIYEVLKDPSRREKYDRVLKEGMP--NWKSALYYYRRMRKIGLYEGAFILFLITTVGQYLFAWAAYLEKKYTAEQVFGTKLKKLQKKNKNIDMDVILS------EIPMPSLLNTLPIQIPLALWNLPRTIKNGFSKANELKELALEKRRQELEAVRRQEELEREAEEQARLRKEHKENLRKRKQNSKAPEKTEEELRGYSQIQTRELTDDDAVRPASQKSTVSGGFWTDEDLTELIRLVKKYPGGAGSRWNTIAESMNRSVQEVTFMAAKMKENGYRIPGQTDSVAEALVQESQQAQRKEKVKKAAANAGASAEKSMLIPETNWTQEQQRALEAAIVKYRKTAGGDRWQKIANSVPEKTKEECLVRYKYLCELVKTQKRAEEEANEPDEDAAAIEEELPEEEPLAPPEPEVAPAAKKLSKREQRRRKRDLSSGEDSDDAYQYEIS----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43613-1", "uniprot_id": "ERJ5_YEAST", "id": "P43613-1", "name": "ER-localized J domain-containing protein 5", "aln": "----------------------------------------MNGYWKPALVVLGLVSLSYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNLRKLSKKYHPDKNP--KYRKLYERLNLATQILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKPKTWFLLAFIWIVVN-IGQYIISIIQYRSQRS----------------------------------------------------------------------------------------------------------------------------------------RIENFISQCKQQDDTNG----------------------------------LGVKQLTFKQHEKDEG------------------------KSLVVRFSDVYVVEPDGSETLISPDT----LDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEE-----------IITDSKKYDGNQTKKGNKVKKGSAKKGQKKMELPNGKVIYSRK---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* . .: : : *:*:* :*:. ***:*: : * :: :: : *.** ***** . . :..* ::*.: ..*: ** * :*:* :::. :*: *:: *:: ::: :*:* . * .:: :: : .: . .. .* ::* : .:. . . . .. : : : . . : . ** : :. : . . .: . ", "identical_positions": 36, "similar_positions": 90, "identity": "6.14%" }, { "cls_id": "homologset.agr.SGD:S000001940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1A2-1", "uniprot_id": "CNDP2_MOUSE", "id": "Q9D1A2-1", "name": "Cytosolic non-specific dipeptidase", "aln": "-------------------------------MSALKAVFQYIDENQDRYVKKLAEWVAIQSVSAWPEK--RGEIRRMMEVAAADVQRLG-GSVELVDIGKQKLPDGS-EIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLV--EREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLVDKKGKILIPGINDAVAPVTDEEHALYDHIDFDMEEFAKDVGAETLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q0N1-1", "uniprot_id": "CNDP2_RAT", "id": "Q6Q0N1-1", "name": "Cytosolic non-specific dipeptidase", "aln": "-------------------------------MSALKAVFQYIDENQDRFVKKLAEWVAIQSVSAWPEK--RGEIRRMTEAAAADVQRLG-GSVELVDIGKQKLPDGS-EIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLV--EREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLIDKKGKILIPGINDAVAPVTDEEHELYDHIDFDMEEFAKDVGAGTLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KP4-1", "uniprot_id": "CNDP2_HUMAN", "id": "Q96KP4-1", "name": "Cytosolic non-specific dipeptidase", "aln": "-------------------------------MAALTTLFKYIDENQDRYIKKLAKWVAIQSVSAWPEK--RGEIRRMMEVAAADVKQLG-GSVELVDIGKQKLPDGS-EIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLV--ERDGKLYGRGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARKDTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPGINEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEFKVYMGHGGKPWVSDFSHPHYLAGRRAMKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRYNYIEGTKMLAAYLYEVSQLKD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQX1-1", "uniprot_id": "A3KQX1_DANRE", "id": "A3KQX1-1", "name": "Cytosolic non-specific dipeptidase", "aln": "-------------------------------MSYLPNLFKYVDEHQNEYVERLAQWVAVQSVSAWPEK--RGEIKKMMEMAGKDIERLG-GTVELVDIGMQKLPSGE-EIPLPPIVLGRLGSDPGKKTVCIYGHLDVQPASIEDGWDSQPFILE--ERDGKMYGRGSTDDKGPVLAWFNIIEAYQKIGQELPINIKFCFEGMEESGSEGLDDLVFSRKDTFFKDVDYVCISDNYWLGKTKPCITYGLRGICYFFIEMECCDKDLHSGVFGGSVHEAMTDLIALMGTLVDNKGKIKVPGIYDQVAKLTDEEKKLYEKIEFDLEEYAKDVGAGKLMHDTKEQILMHRWRYPSLSLHGIEGAFSEAGAKTVIPRKVIGKFSIRLVPDMDPKVVEKQVISHLEKTFAELKSPNKLKVYMGHGAKAWVSDFNHPHYMAGRKAMKTVFGVEPDLTREGGSIPVTLTFQEATGQNVMLLPVGSSDDGAHSQNEKLNRSNYIQGTKMLGAYFYEVSQLS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BUG2-1", "uniprot_id": "CNDP1_MOUSE", "id": "Q8BUG2-1", "name": "Beta-Ala-His dipeptidase", "aln": "-----------------------MFSSAHS--GLLEKLFHYIDLHQDEFVQTLKEWVAIESDSVQPVPRLRQKLFQMMALAADKLRNLG-AGVESIDLGSQQMPDGQ-SLPIPPILLAELGSDPEKPTVCFYGHLDVQPAQKDDGWLTDPYTLT--EVDGKLYGRGATDNKGPVLAWINAVSTFRALQQDLPVNIKFILEGMEEAGSIALEELVMREKDHFFSSVDYIVISDNLWLSQRKPALTYGTRGNCYFTVEVKCRDQDFHSGTFGGILNEPMADLVALLGSLVDSSGHILIPGIYDQMAPITEGEKTMYKNIDMDLEEYQNINQVEKFLFDTKEELLMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVLGKFSIRLVPTMSPSVVEKQVTQHLEAVFSKRNSFNKMAVSMVLGLHPWTANVNDTQYLAAQRTIKTVFGVNPDMIRDGSTIPIAKIFQAITQKSVMMLPLGAVDDGEHSQNEKINRWNYIQGSKLFAAFFLELSKQHSGHQMPSSVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG3-1", "uniprot_id": "CNDP1_RAT", "id": "Q66HG3-1", "name": "Beta-Ala-His dipeptidase", "aln": "-----------------------MLSPPHS--GTLEKLFQYIDLHQDEFVQTLKEWVAIESDSVQPMPRLRQELFRMMALAADKLRNLG-ARVDSVDLGSQQMPDGQ-SLPTPPIILAELGNDPKKPSVCFYGHLDVQPAQKEDGWLTDPYTLT--EVDGKLYGRGATDNKGPVLAWINAVSTFRALQQDLPVNVKFILEGMEEAGSVALEELVKREKDNFFSGVDYIVISDNLWLSQKKPALTCGTRGNCYFTVEVKCRDQDFHSGTFGGILNEPMADLVALLGSLVDSSGHILVPGIYDQMAPITEEEKTMYENIDLDLEEYQKSSRVERFLFDTKEELLTHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVLGKFSIRLVPHMTPSVVETQVTQHLEAVFSKRNSFNKMAVSMVLGLQPWTANINGTQYLAARRAIQTVFGVDPDMIQDGSTIPIAKIFQDITQKSVMMLPLGAVDDGEHSQNEKINRWNYIQGSKLFAAFFLELSKLHSGQQVPSGAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KN2-1", "uniprot_id": "CNDP1_HUMAN", "id": "Q96KN2-1", "name": "Beta-Ala-His dipeptidase", "aln": "MDPKLGRMAASLLAVLLLLLERGMFSSPSPPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLG-ARVASVDMGPQQLPDGQ-SLPIPPVILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLT--EVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAFFLEMAQLH----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6T9-1", "uniprot_id": "A0A8M1P6T9_DANRE", "id": "A0A8M1P6T9-1", "name": "", "aln": "---------------MISISVFCLLLCTGASAFRFEELTQYVNTHQDEFVETLRQWIAVESDSSDVTK--RADLHRMMDMTAEKLRLIG-GKVEMIDIGTQTLANGS-SIDLPKVVTAQFGDDPSKHTVCVYGHVDVQPAKMEDGWSTEPYELT--DLNGNLYGRGASDNKAPVLAWIHALEVYKALNIDPPVNVKLLIEGMEETGSNGLEQMIVAHKDSFFSAVDFIIISDCVWLSKR-PALTYGTRGNCYFCAEVEGPKNDLHSGVYGGTVVEPMTDLIGILDKLISSSGQILVPGIREAVAPLGDEEWSRYQDIEFDLQSFKQDIGLTQLMYSNKVDLLAHRWRHPTVSIHGIEGAFSSPGTKTVIPAKVIGKFSIRQVPDMDPAVVEKQVTDYLHSVFAKRKSPNKLNVTMVIGAKPWLADPKHPLFDAGKAAVKRVFDVEPDLIREGGTIPIARTFQDVTGKSIIMLPIGGFDDGLHSQNEKISRRNYIEGTKLFIAYLYEVSQIKKY--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43616-1", "uniprot_id": "DUG1_YEAST", "id": "P43616-1", "name": "Cys-Gly metallodipeptidase DUG1", "aln": "------------------------------MSHSLTSVFQKIDSLKPQFFSRLTKAIQIPAVSSDESL--RSKVFDKAKFISEQLSQSGFHDIKMVDLGIQPPPISTPNLSLPPVILSRFGSDPSKKTVLVYGHYDVQPAQLEDGWDTEPFKLVIDEAKGIMKGRGVTDDTGPLLSWINVVDAFKASGQEFPVNLVTCFEGMEESGSLKLDELIKKEANGYFKGVDAVCISDNYWLGTKKPVLTYGLRGCNYYQTIIEGPSADLHSGIFGGVVAEPMIDLMQVLGSLVDSKGKILIDGIDEMVAPLTEKEKALYKDIEFSVEELNAATGSKTSLYDKKEDILMHRWRYPSLSIHGVEGAFSAQGAKTVIPAKVFGKFSIRTVPDMDSEKLTSLVQKHCDAKFKSLNSPNKCRTELIHDGAYWVSDPFNAQFTAAKKATKLVYGVDPDFTREGGSIPITLTFQDALNTSVLLLPMGRGDDGAHSINEKLDISNFVGGMKTMAAYLQYYSESPEN--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: : .:.. * : : : : * * .: . : * : :*:* * . . .: * :: ..:*.** * :* .*** ***** *** ::*: * : .* : *** :*:..*: .*:: :..:: : *:*: :*****:** *:::: . : :*. ** : *** *:. * :* * ** *: :: . *:*** :** : *.* **: ::. *:.. *:* : ** : :. : : * *. *.:.::. :.. * ::* * **:*::*:**:****. *:***** :*.****** ** * : * : * . .* *: . : . * :: . : *.: : : *:..:**: ::*.:**:: ** .::::*:* *** ** ***:. *:: * * : *:: :: ", "identical_positions": 131, "similar_positions": 154, "identity": "25.14%" }, { "cls_id": "homologset.agr.SGD:S000001941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZU2-1", "uniprot_id": "TXTP_MOUSE", "id": "Q8JZU2-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "-----------------------------------MAAP-------------RGPRALSAAAPGSGKPKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMR------DAQGRLDSRRGLLCGLGAGVAEAVVVVCPMETIKVKFIH--------------------------DQTSSNPKYRGFFHGVREIIREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNHNKPMNPLITGVFGATAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTLDCGLKILKNEGPKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLLNKVWKTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32089-1", "uniprot_id": "TXTP_RAT", "id": "P32089-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "-----------------------------------MAAP-------------RAPRALTAAAPGSGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMR------DAQGRLDSRRGLLCGLGAGVAEAVVVVCPMETVKVKFIH--------------------------DQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVFGAVAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53007-1", "uniprot_id": "TXTP_HUMAN", "id": "P53007-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "-----------------------------------MPAP-------------RAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMR------DAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIH--------------------------DQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4U0-1", "uniprot_id": "TXTPB_DANRE", "id": "F1R4U0-1", "name": "Tricarboxylate transport protein B, mitochondrial", "aln": "-----------------------------------MSGSPKFVS------PFHRPHCLSAAAP-AGQAKLTHPGKAILAGGIAGGIEICITFPTEYVKTQLQLDEKANPPRYKGIVDCVKQTVQGHGVKGLYRGLSSLLYGSIPKAAVRFGVFEFLSNQMR------DESGKLDSTRGLICGLGAGVAEAVVVVCPMETVKVKFIH--------------------------DQTSANPKYRGFFHGVREIVRTQGLKGTYQGLTATVLKQGSNQAIRFYVMTALRNWYKGDNPNKSINPVVTGLFGAVAGAASVFGNTPLDVIKTRMQGLEAH-KYKSTVDCAIKIMKYEGPAAFYKGTVPRLGRVCMDVAIVFIIYEEVVKVLNKVWKTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PGY3-1", "uniprot_id": "TXTPA_DANRE", "id": "Q6PGY3-1", "name": "Tricarboxylate transport protein A, mitochondrial", "aln": "MSSLYKPFCVSEGPCKDAILRRGCAPLQHPAAPTRIPSPGGGSTRTFTPIPNIYPGQRTLAAAAIGGRKITHPWKAIFAGGIAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVKLTVQYHGLRGLYRGLSSLLYGSIPKSAVRFGTFEVLSNPMR------DATGRLDNKASLLCGLGAGIAEAVLVVCPMETVKVKFIH--------------------------DQCSLRPRYRGFFHGVREIIRDQGVRGTYQGLTATLLKQGSNQAIRFYVMNLLRNWYKGDDPARDMHPLVTAMFGATAGAASVFGNTPLDVVKTRMQGLEAH-RYKSTMDCAFQILKNEGPLAFYKGTVPRLGRVCLDVAIVFVLYEEVVKLLNNVWRTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KSQ0-1", "uniprot_id": "Q7KSQ0_DROME", "id": "Q7KSQ0-1", "name": "Citrate transport protein", "aln": "---------------------------MDRSAFASLVSPYR-----------RRPWMTEHGAAAADSGQVG--LKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAV------DSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETIKVKFIN--------------------------DQRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIRFFVLESLKDLYKGDDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEAS-KYKNTAHCAVEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVWV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43617-1", "uniprot_id": "YFL5_YEAST", "id": "P43617-1", "name": "Uncharacterized mitochondrial carrier YFR045W", "aln": "-----------------------------------------------------------------MANQNSDLYKQITAGSVAAVFQTTMTYPFEYLKTGLQLQPKG-----------TAFEIILPQIKSYFVGCSALNVAAFGKTILRFVTFDKLCHSLNNNIDNNDNFQRLTGYNLLIAGTLTGIVESLFIIP-FENIKTTLIQSAMIDHKKLEKNQPVVNAKATFHKVATKSTPVARIEKLLPAVKHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARN-----DKASSVITGLATSFTLVAMTQPIDVVKTRMMSQNAKTEYKNTLNCMYRIFVQEGMATFWKGSIFRFMKVGISGGLTFTVYEQVSLLLGFSSRS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * **.::. :: :*:* **:** ***: :. . : . . : * * * .:: *: ** *: * * :* . *:.* :*: *::. : :*.:*..:*: : : .: . : .* .: : .* . :* *.*:::* :* :*:* . :: :. : : * :. : * . *:**:**** . :* .*:.* .* .*: ** :*:**:: *: :* :. .:.* :*:.. ::. ", "identical_positions": 62, "similar_positions": 99, "identity": "15.82%" }, { "cls_id": "homologset.agr.SGD:S000001943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91X91-1", "uniprot_id": "NADC_MOUSE", "id": "Q91X91-1", "name": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]", "aln": "MDPEGLQLLLPPTTLAALANSWLQEDCPGLNFASLVTGSAPSQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWFLPEGSKLVP------VVKVAEVKGPAHHLLLGERVALNTLARCSGIASAAATAVEVARSTGWTGHVAGTRKTTPGFRLVEKYGLQVGGAACHRYDLGGMVMVKDNHVVAAGSMERAVLKARQAAGFSLKVEVECSSLEEAFRAAEAGADLVMLDNFKPEELHPTAATLKARFPS---VSVEASGGVTLDNLTQFCGTHIDVISLGMLTQAAPALDFSLKLFAEGDTPVPHARRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0M2-1", "uniprot_id": "NADC_RAT", "id": "Q5I0M2-1", "name": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]", "aln": "MDPEGLQFLLPPASLAALANSWLQEDCPGLNFASLVTGSAPAQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWLLPEGSKLVP------VVKVAEVRGPAHHLLLGERVALNTLARCSGIASAAATAVEVATSTGWAGHVAGTRKTTPGFRLVEKYGLLVGGAECHRYDLGGLVMVKDNHVVAAGSMEKAVLKARQAAGFPLKVEVECSSLKEALQAAEAGADLVMLDNFKPEELHPTAATLKAKFPN---VSVEASGGVTLDNLPQFCGTNIDVISLGMLTQAAPALDFSLKLYAEGDIPVPHARRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15274-1", "uniprot_id": "NADC_HUMAN", "id": "Q15274-1", "name": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]", "aln": "MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVP------VARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPS---VAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43619-1", "uniprot_id": "NADC_YEAST", "id": "P43619-1", "name": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]", "aln": "-MPVYEHLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* : . .** ** *.:::.. * *: :* *:.*. *:*.* ** : :*.* : **.*:: *** * * **:: ***: :**.**.*** *:*.****:*: :. * .:*: * :*********:* :***.: ***. *****..:**:****: *:*.: .** ** ...*.:*:**** * .** .* *****:::***** : *: * ** :: . . :*.***:.**** :: .**: * . : *.:*.:****** ", "identical_positions": 124, "similar_positions": 86, "identity": "40.26%" }, { "cls_id": "homologset.agr.SGD:S000001944", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VXQ8-1", "uniprot_id": "Q9VXQ8_DROME", "id": "Q9VXQ8-1", "name": "DUF155 domain-containing protein", "aln": "-------------------------------------------------------MNFARLRFGQMVLGGLRIPRQQTQTQWMMDRRRWLASEATSSAAAPAQAASVPRTQTQPR-----------VKPLP------------LAEERLESILSPIRTRIIRKKRLAIDELSALGFLNTR------------GYTTAEEYNLEDLQIALRE-----------------------------------------------------------------------QNLYETKRFFSTDNLDVEQNVLFVAAKYPTGQQ----PREIFFFREGSVVFWN-----------------------------------------------------------------CSDIETNNVLSFLRAFERES---YVSALVHGESEVMPYTYIPSTAVDVEGDLVAESSD---FNVTSRAFFQNGKFFVTADTDS----------------FLYKYTFSNAMAQSIKLGMWEATLDRYIDSIEHLTEDLKRGRRLRISRAAMLRKTGELFALRHVINLSSDLLDAPDFYWDRE-ELEALYLQVCSYFSISRRTKVMNEKINHCVELAELVSHNLNDAHHIRLEWMIIILIMVEVGFEVLHFVSDHSDSHKLEVLPLAAPAASIPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43620-1", "uniprot_id": "RMD8_YEAST", "id": "P43620-1", "name": "Sporulation protein RMD8", "aln": "MSYKANQPSPGEMPKRSPSILVTDARTSKNRMSAPFAGHAAGSRKNMENAGVTKSQGVRSSAIGPSPLQSFTHPRRRSSGRFSDISIDNILSDNSDIPSARREERLSSSSSDRPRQYERLSSRRKMINPLPPRTSKTSQKLVLIPEDDNLNHFQTLPTNALDRQRPKVGSMKSNSFDRLPRYSKEKSMARITAYNVADGFNLNQLYKFLQETHEVSPRLYDECLYVAYTLPLLPGKGGFRIKSNLSKKTMGGKTLIDNLIDTSEQRDHHYEYYSGVETVEDANNNYELETSGNNNNANQDTTTVPDHLPNPVGQQDSFNPMEPQFFAEETPLEIEKRERTERINMLKKEENDSDASCGNDNNNKNNDKSKLYAVEGNDQYVQSSRSPASPSSISTPSPPSSSQNDFDRVYKMHRDNDHEGNDRHAEIFIFHYGVIVFWNFTEIQEKNILGDITFADYKNLMIRPLDEQDIETEQFHFEYDRDTERPRIFNDIVTLRSGDHIIELTLSHAIAQSSKLSRFESRISPILISVTKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSTILDTPEFFWSFEPSLHPLYVAMREYLEIDQRVQVLNDRCKVFLEFFDICVDSVAERNMARVTWWFILVILFGVIFSLTEIFVRYVIIHRHTST-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :* * .: **:::. :: : *: :. .:* : . :. :** ::*** :.*: . :..: *. : ::* :..:.: .* . .*..*: :**::* *:* :* ** : ..:* : : ..: *.*** * * ** * : : : .*: : :.* .: * ::*. :.. ::. . :: :.: :: **:. . . :. .. ::. :*.. * *: .: : *:*:*:*** **. :*: :. : *: :*.: * * :.* :*:*:*:** ** :**** :**:*:*:*. * .*..**: : .*:.*.:*.:*:*:: : :*: :: ..: : : *: * :*::*:. * *.: .:. : *: ", "identical_positions": 91, "similar_positions": 171, "identity": "13.52%" }, { "cls_id": "homologset.agr.SGD:S000001946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34067-1", "uniprot_id": "PSB4_RAT", "id": "P34067-1", "name": "Proteasome subunit beta type-4", "aln": "MEAFWESRTG-HWAGGPAPGQFYRVP--STPSCLMD-PMSAPAR-PITRTQNPMVTGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVLGQMVID----EELFGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGYAG-GESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ---PVLSQTEARELVERCMRVLYYRDARSYNRFQVATVTEK-GVEIEGPLSAQ-TNWDIAHMISGFE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P99026-1", "uniprot_id": "PSB4_MOUSE", "id": "P99026-1", "name": "Proteasome subunit beta type-4", "aln": "MEAFWESRAG-HWAGGPAPGQFYRIP--ATPSGLMD-PASAPCEGPITRTQNPMVTGTSVLGVKFDGGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVLGQMVID----EELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYAD-GESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ---PVLSQTEARELVERCMRVLYYRDARSYNRFQIATVTEK-GVEIEGPLSAQ-TNWDIAHMISGFE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28070-1", "uniprot_id": "PSB4_HUMAN", "id": "P28070-1", "name": "Proteasome subunit beta type-4", "aln": "MEAFLGSRSG-LWAGGPAPGQFYRIP--STPDSFMD-PASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVID----EELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYAD-GESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ---PVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEK-GVEIEGPLSTE-TNWDIAHMISGFE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNA5-1", "uniprot_id": "PSB4_DROME", "id": "Q9VNA5-1", "name": "Proteasome subunit beta type-4", "aln": "MLNNYNSLAQPMWQNGPAPGEFYNFTGGQTPVQQLPRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVMLAADTLVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIE----DQCCDDNIEMKPKSLASWMTRVLYNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGFARHLAVPLVREKKPKD---RDFTAVEASELIRTCMEVLYYRDTRNISQYTVGVCSVN-GCGVEGPFQVN-ENWTFAETIKGY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30657-1", "uniprot_id": "PSB7_YEAST", "id": "P30657-1", "name": "Proteasome subunit beta type-7", "aln": "MNHDPFSWGR------PADSTYGAYN----------TQIANAGASPMVNTQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ** . : : .: . .*****:.:::: **::*** * ****: *:..:.*:: *... ::* *** :*:* ::: : : : : : . .* : .::: .:*.***:****: ::.* . * :* *:: * :*. :***:. ::* **:*: :: : * : : .*.******:*. .: :. : * .: :..: :* :*. *.*: ", "identical_positions": 64, "similar_positions": 91, "identity": "22.7%" }, { "cls_id": "homologset.agr.SGD:S000001947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H80-1", "uniprot_id": "COPD_RAT", "id": "Q66H80-1", "name": "Coatomer subunit delta", "aln": "MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTG-KQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALG-YRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQG--------KKAPGFG--GFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIM----------SSNMGKRTSEAAKVHAPPINMES-VHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKFGRIRLHVEN---EDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVN-SDVGVLKWRLQT--TEESFIPLTINCWPSESGNG--CDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVID---AKNKSGSLEFSIPG-QPNDFFPVQVSFISKK------NYCNIQVTKVTQVDG-NSPVRFSTETTFLVDKYEIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJY5-1", "uniprot_id": "COPD_MOUSE", "id": "Q5XJY5-1", "name": "Coatomer subunit delta", "aln": "MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTG-KQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALG-YRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQG--------KKAPGFG--GFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIM----------SSNMGKRTSEATKVHAPPINMES-VHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKFGRIRLHVEN---EDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVN-SDVGVLKWRLQT--TEESFIPLTINCWPSESGNG--CDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVID---AKNKSGSLEFSIPG-QPNDFFPVQVSFISKK------NYCNIQVTKVTQVDG-NSPVRFSTETTFLVDKYEIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48444-1", "uniprot_id": "COPD_HUMAN", "id": "P48444-1", "name": "Coatomer subunit delta", "aln": "MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTG-KQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALG-YRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQG--------KKAPGFG--GFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIM----------SSSMGKRTSEATKMHAPPINMES-VHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKYGRIRLHVEN---EDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVN-SDVGVLKWRLQT--TEESFIPLTINCWPSESGNG--CDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVID---AKNKSGSLEFSIAG-QPNDFFPVQVSFVSKK------NYCNIQVTKVTQVDG-NSPVRFSTETTFLVDKYEIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W555-1", "uniprot_id": "Q9W555_DROME", "id": "Q9W555-1", "name": "Coatomer subunit delta", "aln": "MVLIAAAVCTKNGKVILSRQFVEMTKARIEGLLAAFPKLMTAG-KQHTYVETDSVRYVYQPMEKLYMLLITTKASNILEDLETLRLFSKVIPEYSHSLDEKEIVENAFNLIFAFDEIVALG-YRESVNLAQIKTFVEMDSHEEKVYQAVRQTQERDARQKMREKAKELQRQRMEASKRGGPSLGGIGSRSGGFSADGIGSSGVSSSSGASSANTGITSIDVDTKSKAAASKPASRNALKLGGKSKDVDSFVDQLKNEGEKIANLAPAAPAGGSSAAASASAAAKAAIASDIHKES-VHLKIEDKLVVRLGRDGGVQQFENSGLLTLRITDEAYGRILLKLSP---NHTQGLQLQTHPNVDKELFKSRTTIGLKNLGKPFPLN-TDVGVLKWRFVS--QDESAVPLTINCWPSDNGEGG-CDVNIEYELEAQQLELQDVAIVIPLPMNV-QPSVAEYDGTYNYDSRKHVLQWHIPIID---AANKSGSMEFSCSASIPGDFFPLQVSFVSKT------PYAGVVAQDVVQVDS-EAAVKYSSESILFVEKYEIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43621-1", "uniprot_id": "COPD_YEAST", "id": "P43621-1", "name": "Coatomer subunit delta", "aln": "MVVLAASITTRQGKPLLSRQFKDLSKDRVLELLSNFQNLVSEISSDHTFVEDKHVRYVYRPFDNYYIILITNRQSNIIKDLATLNLFSQTINSYLSSFQDQEIFHNAFEILSSFDEIVSMGGYKENLSFTQVQTYLSMESHEERIQEIIERNKEIEATEERKRRAKEIARKEHERKHGFMSS---NGDYDGANRFMGSKDPNVTNAINSYYSHASPAAQQSYLQSSHAAAAEVAPVASPMATSQRAGHSATGGMKLGGGAGRRAG---AAPRPSAISSASSGTPPPPEEDVPENNGILISIKEVINAEFSRDGTIHSSELKGVLELRINDHDLSHSNLKLADSIDVRDKSFQFKTHPNIDKQSFLSTKLISLRDKSKAFPANDQSLGVLRWRKVAPAEDDSLIPLTLTTWVSPSESQQGFDVIIEYES-VLETELADVIFTIPVFPQEPVDINTESSTCSDAEVVNMDQEMGTSIKISKIAANDAGALAFTIEAPYEDALYPMTVSFQESTRDKLAKSFTGMAIQSVVMANDHDQELPYDVITSLKSDEYLVQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::**:: *: ** ::**** :::: *: **: * :*:. .:**:** . *****:*::: *::***.: ***::** **.***:.* .* :::::** .:.*::: :*****::* *:*.:.::*::*: .*:****:: . :...:* :* : :.:***: : . : .: . . * .. *:.. : : : .* . * :. . : .. .. :* * .* .. :: : : :. : :.*:: : .*** ::. * *:: ***.*. .: *:: :..*::****:**: * : . *.*:: *.** * .:***:** : ::* :***:. * * . . ** **** : ** ** :.**: * . : . : .: * *.:*:: *: . . ::*: *** ... : .: .*. .:. : : :. : : ::* : ", "identical_positions": 131, "similar_positions": 190, "identity": "23.69%" }, { "cls_id": "homologset.agr.SGD:S000001948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMQ3-1", "uniprot_id": "F1LMQ3_RAT", "id": "F1LMQ3-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRTAKAPRGEPRRSSRRGQKLAVVAPPPALGSTSRPHFRRESIARRRCRKSGRLFAASRKMAAAAATVNGTTGVSSSGPAATSGGILQAAAGMYEQLKDEWNRKSPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWLLGPNNYYS--FASQQQKPEDSTIPSTE----LARQVIEYARQLEMIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX56-1", "uniprot_id": "PSMD8_MOUSE", "id": "Q9CX56-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRAAKTPRGEPRRSSRGGRKLAVVAPPPVLGSTSRPHFRRESIARRRCRKSGRRLAASRKMAATAATVNGSTTVSSSGPAATSVGILQAAAGMYEQLKDEWNRKNPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWVLGPNNYYS--FASQQQKPEDSTIPSTE----LAKQVIEYARQLEMIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48556-1", "uniprot_id": "PSMD8_HUMAN", "id": "P48556-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRAPRAPPRERRRATRGG-LRQVVAPPRALGSTSRPHFRRASVCRRRCRKSGGLLAASRKMAAAA--VNGAAGFSSSGPAATSGAVLQAATGMYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTEATRILFFNTPKKMTDYAKKRGWVLGPNNYYS--FASQQQKPEDTTIPSTE----LAKQVIEYARQLEMIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V436-1", "uniprot_id": "Q9V436_DROME", "id": "Q9V436-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "------------------------------------------------------------------------------------------MANVESLYKELTAEWSKRPPNTVKCGQLLDQLKVALVKMA-FLPTDGNDAQSSKKQLILARSVLEVAVEHSVLSKDLLAFERYMAQLKCYYYDYAKIIGESESKYKLLGLNLLYLLSGNRVSDFHTELELLS--VDVIQHNQFIRPILALEQYIMEGRYNKIF--QAKSTVPVEVYSYFMDLLLETVRDEIGACIEKSYDKISAKDAAKRLNLRVPDEIKAFGAKRQWKLEASGDYS--FTDRSVKPKE-LLPSEE----LAEQVLSYARDLEMIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32496-1", "uniprot_id": "RPN12_YEAST", "id": "P32496-1", "name": "26S proteasome regulatory subunit RPN12", "aln": "------------------------------------------------------------------------------------------MPSLAELTKSLSIAFE--NGDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLNDLMITKRILEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSELQYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQNISEFDSFTDILKSAIRDEIAKNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVYFNNQSKEKADYEDEMMHEEDQKTNIIEKAMDYAISIENIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.*. :. : * : * :*: *:: ::* . . ::*:::: :**:.. *: :: :**.*: *** **:. . : ** :*:.* ** *** *..:.**:**: * . :: : : : *::::*** *:* : ... . : * *:* .::****. * :*: : : * : .: :. :* * : . * :... . :: : . : : .:.:.** .:* **", "identical_positions": 57, "similar_positions": 98, "identity": "15.57%" }, { "cls_id": "homologset.agr.SGD:S000001949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27926-1", "uniprot_id": "HXK3_RAT", "id": "P27926-1", "name": "Hexokinase-3", "aln": "----------------------------------------MAAIEPSGLHPGERDSSCPQEGIP-----RPSGSLELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFGGCASPALLSQNSILLEHVAKMEDPATGIAHVHTVLQGLGLSPQASDAELVQRVCMAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMREAMIRGLQGE---SSSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEG-----SVQITNQVYSIPEYVAQ-GSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPGDSGH-------MCINMEWGAFGDDGSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQCLQTRDIFKTKFLSEIESDSLA-LRQVRAILEDLGLTLTSD-DALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTVRKLA------PQCTVTFLQSEDGSGKGAALVTRVACRLTQMACV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TRM8-1", "uniprot_id": "HXK3_MOUSE", "id": "Q3TRM8-1", "name": "Hexokinase-3", "aln": "----------------------------------------MATIGPSGLHPGERASVCPHEGVP-----RPSGSLEL--ECLQQFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVLFDGCASPALLSQGCILLDHVAEMEDTATGTARVHTILQDLGLSPRASDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLRILKETVTLLAPNCDVSFIPSVDGGGRGVAMVTAVAARLAAHRRILEETLAPFQLTLEQMTVVQAQMREAMIRGLQGE---ASSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEG-----SVQIINQVYSIPECRAQ-GSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPGDSGL-------MCINMEWGAFGDDGSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQCLQARDIFKTKFLSEIESDSLA-LRQVRAILEDLGLTLTSD-DALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATVRKLA------PQCTVTFLQSEDGSGKGAALVTAVACRLTQMAHV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52790-1", "uniprot_id": "HXK3_HUMAN", "id": "P52790-1", "name": "Hexokinase-3", "aln": "----------------------------------------MDSIGSSGLRQGEETLSCSEEGLP-----GPSDSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIRRQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVSVEWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHVCAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLLAPECDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGE---ASSLRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG------VQITSEIYSIPETVAQ-GSGQQLFDHIVDCIVDFQQKQGLS--GQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGR-------MCINMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESDSLA-LRQVRAILEDLGLPLTSD-DALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELA------PRCVVTFLQSEDGSGKGAALVTAVACRLAQLTRV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91W97-1", "uniprot_id": "HKDC1_MOUSE", "id": "Q91W97-1", "name": "Hexokinase HKDC1", "aln": "----------------------------------------MFAVHLVAFYFTKLKEDQ----------------IKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTASVKMLPTFVRAIPDGSENGEFLSLDLGGS--KFRVLKVQVSQEGQQNVQMESQFYPMPNEITRGNGTELFDYVADCLADFMKTKNLTHKKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGVQDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLGLEPSESDCIAVQHVCTIVSFRSANLCAAALATILTRLRENKKLARLRTTVGMDGTLYKTHPQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLTREQLLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRVLLVKIR-----RRSVRMYNKIFAIPLEIMQ-GTGEELFDHIVQCIADFLDYMGLK--GAQLPLGFTFSFPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMMTCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGR-------MCVNTEWGGFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFETKFLSQIESDRLA-LLQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELA------PQCDVTFMLSEDGSGKGAALITAVAKRLQQPRKDI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R3X7-1", "uniprot_id": "M0R3X7_RAT", "id": "M0R3X7-1", "name": "hexokinase", "aln": "----------------------------------------MFAVHLVAFYFTKLKEDQ----------------IKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTASVKMLPTFVRAIPDGSENGEFLSLDLGGS--KFRVLKVQVSEEGKQNVQMESQFYPMPNEITRGNGTELFDYVADCLADFMKTKDLTHKKLPLGFTFSFPCRQNKLEEGFLLSWTKKFKARGVQDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGTLEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLGLDPSESDCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLARLRTTVGMDGTLYKTHPQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFHLTREQLLGVRDKMRAELEYGLKKKTHALATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRVLLVKIR-----KRSVRMYNKIFAIPLEIMQ-GTGEELFDHIVQCIADFLDYMGLK--GAQLPLGFTFSFPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMMTCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGR-------MCVNTEWGGFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFETKFLSQIESDRLA-LLQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKDLA------PQCDVTFMLSEDGSGKGAALITAVAKRLQQLPKDN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TB90-1", "uniprot_id": "HKDC1_HUMAN", "id": "Q2TB90-1", "name": "Hexokinase HKDC1", "aln": "----------------------------------------MFAVHLMAFYFSKLKEDQ----------------IKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGS--KFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG---RRSVRMYNKIFAIPLEIMQ-GTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK-------MCINTEWGGFGDNGCIDDIWTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLA-LLQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELA------PRCDVTFMLSEDGSGKGAALITAVAKRLQQAQKEN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17710-1", "uniprot_id": "HXK1_MOUSE", "id": "P17710-1", "name": "Hexokinase-1", "aln": "MGWGAPLLSRMLHGPGQAGETSPVPERQSGSENPASEDRRPLEKQCSHHLYTMGQNCQRGQAVDVEPKIRPPLTEEKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGS--SFRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGRITPELLTRGKFTTSDVAAIETDKEGVQNAKEILTRLGVEPSHDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGK--KRTVEMHNKIYSIPLEIMQ-GTGDELFDHIVSCISDFLDYMGIK--GPRMPLGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEGNQGQ-------MCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLA-LLQVRAILQQLGLNSTCD-DSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELS------PKCTVSFLLSEDGSGKGAALITAVGVRLRGDPTNA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05708-1", "uniprot_id": "HXK1_RAT", "id": "P05708-1", "name": "Hexokinase-1", "aln": "----------------------------------------MIAAQLLAYYFTELKDDQ----------------VKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGS--SFRILRVQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDKEGIQNAKEILTRLGVEPSDVDCVSVQHICTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGK--KRTVEMHNKIYSIPLEIMQ-GTGDELFDHIVSCISDFLDYMGIK--GPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNVEMVEGNQGQ-------MCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLA-LLQVRAILQQLGLNSTCD-DSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELS------PKCTVSFLLSEDGSGKGAALITAVGVRLRGDPSIA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19367-1", "uniprot_id": "HXK1_HUMAN", "id": "P19367-1", "name": "Hexokinase-1", "aln": "----------------------------------------MIAAQLLAYYFTELKDDQ----------------VKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS--SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGK--KRTVEMHNKIYAIPIEIMQ-GTGEELFDHIVSCISDFLDYMGIK--GPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQ-------MCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLA-LLQVRAILQQLGLNSTCD-DSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELS------PKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08528-1", "uniprot_id": "HXK2_MOUSE", "id": "O08528-1", "name": "Hexokinase-2", "aln": "----------------------------------------MIASHMIACLFTELNQNQ----------------VQKVDQYLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGT--NFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEDDKDGIQKAYQILVRLGLSPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHEAAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGK--RRGVEMHNKIYSIPQEVMH-GTGEELFDHIVQCIADFLEYMGMK--GVSLPLGFTFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIRRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGR-------MCVNMEWGAFGDNGCLDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLA-LLQVRAILRHLGLESTCD-DSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLA------PKCDVSFLESEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27881-1", "uniprot_id": "HXK2_RAT", "id": "P27881-1", "name": "Hexokinase-2", "aln": "----------------------------------------MIASHMIACLFTELNQNQ----------------VQKVDQFLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGT--NFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEEDKDGIEKAYQILMRLGLNPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHAVAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGK--RRGVEMHNKIYSIPQEVMH-GTGEELFDHIVQCIADFLEYMGMK--GVSLPLGFTFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGR-------MCVNMEWGAFGDNGCLDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLA-LLQVRAILRHLGLESTCD-DSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLA------PKCDVSFLESEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52789-1", "uniprot_id": "HXK2_HUMAN", "id": "P52789-1", "name": "Hexokinase-2", "aln": "----------------------------------------MIASHLLAYFFTELNHDQ----------------VQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGT--NFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGK--WGGVEMHNKIYAIPQEVMH-GTGDELFDHIVQCIADFLEYMGMK--GVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR-------MCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLA-LLQVRAILQHLGLESTCD-DSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLA------PKCDVSFLQSEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52792-1", "uniprot_id": "HXK4_MOUSE", "id": "P52792-1", "name": "Hexokinase-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEATKKEKVEQILAEFQLQEEDLKKVMSRMQKEMDRGLKLETHQEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMT-GTAEMLFDYISECISDFLDKHQMK--HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGR-------MCVNTEWGAFGNSGELDEFLLEYDRMVDESSVNPGQQLYEKIIGGKYMGELVRLVLLKLVEENLLFHGEASEQLRTRGAFETRFVSQVESDSGD-RRQILNILSTLGLRPSVA-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT------PNCEITFIESEEGSGRGAALVSAVACKKACMLGQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17712-1", "uniprot_id": "HXK4_RAT", "id": "P17712-1", "name": "Hexokinase-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEATKKEKVEQILAEFQLQEEDLKKVMSRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMT-GTAEMLFDYISECISDFLDKHQMK--HKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGR-------MCVNTEWGAFGDSGELDEFLLEYDRMVDESSANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGD-RKQIHNILSTLGLRPSVT-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT------PNCEITFIESEEGSGRGAALVSAVACKKACMLAQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35557-1", "uniprot_id": "HXK4_HUMAN", "id": "P35557-1", "name": "Hexokinase-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMT-GTAEMLFDYISECISDFLDKHQMK--HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGR-------MCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGD-RKQIYNILSTLGLRPSTT-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT------PSCEITFIESEEGSGRGAALVSAVACKKACMLGQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NFT7-1", "uniprot_id": "HXK2_DROME", "id": "Q9NFT7-1", "name": "Hexokinase-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MR----KSTRLLTHS-------------LFGPVFKILFHNKTVCGGCNRKMPSLVNTEIEAAVKG----------------------------FLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLVNLISNS----DVETMSKGYNFPQTLMS-GSGKALFDFLAECLSEFCHSHGLE--NESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPS---MIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNIN------EVAIGIDGSVYRFHPKYHDMLQYHMKKLLK-----PGVKFELVVSEDGSGRGAALVAATAVQAKSKL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W330-1", "uniprot_id": "Q9W330_DROME", "id": "Q9W330-1", "name": "Phosphotransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRELNGAMKSVSINSAQLNGHNNGGGLDETDRVGVAQGAALSATEKITTTTAAATKSATATTNATTATATTTNLTTHSPQQIALLSAAEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFLALDLGGTNFRVLLIHLQENN----DFQMESRIYAIPQHIMI-GSGTQLFDHIAECLSNFMAEHNVY--KERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPR-KKH---VLINTEWGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEP------TVTVGVDGSVYRFHPKFHNLMVEKISQLIK-----PGITFDLMLSEDGSGRGAALVAAVACREDILNGKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04806-1", "uniprot_id": "HXKA_YEAST", "id": "P04806-1", "name": "Hexokinase-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNH----TFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDN-EHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSLGIIGA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9NFT9-1", "uniprot_id": "HXK1_DROME", "id": "Q9NFT9-1", "name": "Hexokinase-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANTFNPEEDFPEVYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLVKFSSER----DIYTSSKCVIMPHTVAA-GRGTEVFTFLATSIANFVKEKKVD--KDNLPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLALCWAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYR-----KLMIINSDWAHFGDTGQLDFIRNEYDRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMRLP------QISIAVDGGIYRLHPTFSTVLNKYTRLLAD-----PNYNFEFVITQDSCGVGAAIMAGMAHANKYKTDAKLFTMDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : : ** . . : * * * * *.:*:::: :* *::*:.. . :* :: .: .: :* : :.**::*::. : : . * *** * . ..::. :*:: : : . :: .::* ..:::: : . .:*:* *: * .: : . : :* ::. *.: : :* :* : ..* : :** .. :**::* :: : . :: . : : : * . :: : : * : *:* : .*: : :: :. ** :*. :* : : . . :: :::..* ***::: . ", "identical_positions": 50, "similar_positions": 137, "identity": "4.99%" }, { "cls_id": "homologset.agr.SGD:S000001957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63ZV7-1", "uniprot_id": "SWI5_RAT", "id": "Q63ZV7-1", "name": "DNA repair protein SWI5 homolog", "aln": "--MIDEGEEVTEETLNSDIQKLKEKQDMLDKEISQLIAEGYRVIELEQ-HISLLHEYNDIKDVSQMLLGKLAVTRGVTTKELYPDFDLNPND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3D3-1", "uniprot_id": "SWI5_MOUSE", "id": "Q8K3D3-1", "name": "DNA repair protein SWI5 homolog", "aln": "--MIDENNDVSEEALSSDIKKLKEKHDMLDKEISQLIAEGYRVIELEK-HISLLHEYNDIKDVSQMLLGKLAVTRGVTTKELYPDFDLNLND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P89114-1", "uniprot_id": "SAE3_YEAST", "id": "P89114-1", "name": "Pachytene arrest protein SAE3", "aln": "MNYLETQLNKKQKQIQ-EYESMNGNLIKMFEQLSKEKKNDETPKKISSTYIKELKEYNELRDAGLRLAQIIADEKQCKIKDVFEEIGYSMKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .:: :. : :.:: : : :::*: :. ::.. :*. *:***:::*.. * :* : . *::: ::. . :*", "identical_positions": 11, "similar_positions": 44, "identity": "11.96%" }, { "cls_id": "homologset.agr.SGD:S000002100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTZ4-1", "uniprot_id": "D3ZTZ4_RAT", "id": "D3ZTZ4-1", "name": "V-type proton ATPase subunit G", "aln": "MCSLLTKQAEFGGDPLGNKRACASQLPQTSPSLEQDTMTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQREKEFRLKQSKIMGSQSHLSDELEEQTLEKIKELSGSYHKCMDSVIKQLLSMVCEMKPEVHVNYRATS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMC1-1", "uniprot_id": "VATG3_MOUSE", "id": "Q8BMC1-1", "name": "V-type proton ATPase subunit G 3", "aln": "-------------------------------------MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQMEKDFRLKQAKIMGSQSHLSDEIEEQTLEKIKELNGSYNKCMESVIKQLLSMVCDMKPEVHVNYRATN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LB4-1", "uniprot_id": "VATG3_HUMAN", "id": "Q96LB4-1", "name": "V-type proton ATPase subunit G 3", "aln": "-------------------------------------MTSQSQGIHQLLQAEKRAKDKLEEAKKRKGKRLKQAKEEAMVEIDQYRMQRDKEFRLKQSKIMGSQNNLSDEIEEQTLGKIQELNGHYNKYMESVMNQLLSMVCDMKPEIHVNYRATN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CR51-1", "uniprot_id": "VATG1_MOUSE", "id": "Q9CR51-1", "name": "V-type proton ATPase subunit G 1", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSSEVEKETREKMTVLQNYFEQNRDEVLDNLLAFVCDIRPEIHENYRING", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B3N3-1", "uniprot_id": "A0A8I6B3N3_RAT", "id": "A0A8I6B3N3-1", "name": "V-type proton ATPase subunit G", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSSEVEKETQEKMTILQNYFEQNRDEVLDNLLAFVCDIRPEIHENYRING", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75348-1", "uniprot_id": "VATG1_HUMAN", "id": "O75348-1", "name": "V-type proton ATPase subunit G 1", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCSTEVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDIRPEIHENYRING", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBR5-1", "uniprot_id": "Q6PBR5_DANRE", "id": "Q6PBR5-1", "name": "V-type proton ATPase subunit G", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVAEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKTKEAAALGSHGNSAVEVDKETVDKMGRIQGSYQQNKEAVLGNLLKMVCDIKPEIHANYRVAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WTT4-1", "uniprot_id": "VATG2_MOUSE", "id": "Q9WTT4-1", "name": "V-type proton ATPase subunit G 2", "aln": "-------------------------------------MASQTQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCEVRPQVHPNYRVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R2H0-1", "uniprot_id": "Q8R2H0_RAT", "id": "Q8R2H0-1", "name": "V-type proton ATPase subunit G", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLTQLLGMVCDVRPQVHPNYRITV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95670-1", "uniprot_id": "VATG2_HUMAN", "id": "O95670-1", "name": "V-type proton ATPase subunit G 2", "aln": "-------------------------------------MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZH6-1", "uniprot_id": "VATG_DROME", "id": "Q9XZH6-1", "name": "V-type proton ATPase subunit G", "aln": "-------------------------------------MASQTQGIQQLLAAEKKAAEKVAEARKRKARRLKQAKDEATEEIEKFRQERERAFKEFEAKHMGSREGVAAKIDADIRVKLADMDRAIQTRKDPFILEILQYVYNISPEVHKNYNHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48836-1", "uniprot_id": "VATG_YEAST", "id": "P48836-1", "name": "V-type proton ATPase subunit G", "aln": "--------------------------------------MSQKNGIATLLQAEKEAHEIVSKARKYRQDKLKQAKTDAAKEIDSYKIQKDKELKEFEQKNAGGVGELEKKAEAGVQGELAEIKKIAEKKKDDVVKILIETVIKPSAEVHINAL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:** ** ***.* : : .*:* : :*:*** :* * :.:: : :: :: : *. : : :: :. . : .: :: * . .::* * ", "identical_positions": 22, "similar_positions": 38, "identity": "14.19%" }, { "cls_id": "homologset.agr.SGD:S000002101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35153-1", "uniprot_id": "BET1L_MOUSE", "id": "O35153-1", "name": "BET1-like protein", "aln": "MAD-WTRAQSSGAVEDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLCGMAVVLIVAFFILSYLLSRTRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35152-1", "uniprot_id": "BET1L_RAT", "id": "O35152-1", "name": "BET1-like protein", "aln": "MAD-WTRAQSSGAVEEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLCGMAVVLIVAFFILSYLFSRTRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYM9-1", "uniprot_id": "BET1L_HUMAN", "id": "Q9NYM9-1", "name": "BET1-like protein", "aln": "MAD-WARAQSPGAVEEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLSRART", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EL3-1", "uniprot_id": "BET1L_DANRE", "id": "Q68EL3-1", "name": "BET1-like protein", "aln": "MADPWNRG--HGAVDDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRMQN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43682-1", "uniprot_id": "SFT1_YEAST", "id": "P43682-1", "name": "Protein transport protein SFT1", "aln": "MSN---------SRYSQTESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSVINQMTDSLGSMFTDIKNSSSRLTRSLKAG---NSIWRMVGLALLI-FFILYTLFKLF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : . : :*.* :.**.*:: ::.: :*. : .:. :: * ..: * :..* .*:: ::* ..: :.: *:: **:* :.. ", "identical_positions": 16, "similar_positions": 47, "identity": "14.29%" }, { "cls_id": "homologset.agr.SGD:S000002104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62918-1", "uniprot_id": "RL8_MOUSE", "id": "P62918-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62919-1", "uniprot_id": "RL8_RAT", "id": "P62919-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62917-1", "uniprot_id": "RL8_HUMAN", "id": "P62917-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A6W6-1", "uniprot_id": "D4A6W6_RAT", "id": "D4A6W6-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRDQRKGAGSVFRAHLKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRSAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVQGVAMNPVEHPFGGDNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P0V6-1", "uniprot_id": "RL8_DANRE", "id": "Q6P0V6-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRGQRKGAGSVFKAHVKHRKGAAKLRHIDFAERHGYIKGIVKDIIHDPGRGAPLAKVMFRDPYRFKKRTELFIAAEGIHTGQFIYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKSRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQDKEN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3G1-1", "uniprot_id": "RL8_DROME", "id": "Q9V3G1-1", "name": "Large ribosomal subunit protein uL2", "aln": "MGRVIRAQRKGAGSVFKAHVKKRKGAAKLRSLDFAERSGYIRGVVKDIIHDPGRGAPLAVVHFRDPYRYKIRKELFIAPEGMHTGQFVYCGRKATLQIGNVMPLSQMPEGTIICNLEEKTGDRGRLARTSGNYATVIAHNQDTKKTRVKLPSGAKKVVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGKASTVKRGTSAGRKVGLIAARRTGRIRGGKGDSKDK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX45-1", "uniprot_id": "RL2A_YEAST", "id": "P0CX45-1", "name": "Large ribosomal subunit protein uL2A", "aln": "MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *******:* :* : *:***:** :*:*** ***:*:**:*:**.**.**** * *****::: * *:*** **:*****:*.*:** *::***:*:. :*****:. :***.**** ***:****. :*.** : :*:**:****:***:.* *.::*::*****:***:******:***: ***.**:.:*******:**.**.*******.**: *.: :*:*.********* :** : .. ", "identical_positions": 158, "similar_positions": 69, "identity": "61.48%" }, { "cls_id": "homologset.agr.SGD:S000002127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQS8-1", "uniprot_id": "SC61B_MOUSE", "id": "Q9CQS8-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIAAVFMLHIWGKYTRS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60468-1", "uniprot_id": "SC61B_HUMAN", "id": "P60468-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LXI6-1", "uniprot_id": "A0ABK0LXI6_RAT", "id": "A0ABK0LXI6-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSATNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52871-1", "uniprot_id": "SC6B2_YEAST", "id": "P52871-1", "name": "Protein transport protein SBH2", "aln": "MAASVPPG------GQ---RILQKRRQAQSIKEKQAKQTPTSTRQAGYGGSSSSILKLYTDEANGFRVDSLVVLFLSVGFIFSVIALHLLTKFTHII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*....*.. *: : : * ..:::::: . * : ...:..: ::**::: *::*..: **.:*: ** :*: **: *:*: ", "identical_positions": 19, "similar_positions": 44, "identity": "19.59%" }, { "cls_id": "homologset.agr.SGD:S000002128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQS8-1", "uniprot_id": "SC61B_MOUSE", "id": "Q9CQS8-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIAAVFMLHIWGKYTRS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXI6-1", "uniprot_id": "A0ABK0LXI6_RAT", "id": "A0ABK0LXI6-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSATNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60468-1", "uniprot_id": "SC61B_HUMAN", "id": "P60468-1", "name": "Protein transport protein Sec61 subunit beta", "aln": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52870-1", "uniprot_id": "SC6B1_YEAST", "id": "P52870-1", "name": "Protein transport protein SBH1", "aln": "MSSPTPPG------GQ---RTLQKRKQGSSQK-------VAASAPKKNTNSNNSILKIYSDEATGLRVDPLVVLFLAVGFIFSVVALHVISKVAGKLF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..***.. *: ::: * **: : : ** :..: ....: ::*::::.**:*.*: **.::: ** :*. **: .* : . ", "identical_positions": 23, "similar_positions": 40, "identity": "23.47%" }, { "cls_id": "homologset.agr.SGD:S000002129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2R4-1", "uniprot_id": "TMD11_MOUSE", "id": "Q9D2R4-1", "name": "Transmembrane emp24 domain-containing protein 11", "aln": "--------------MQIQT------ILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLES-APGLGMFVTVTTY--NDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMK---HLKDFFIAKKLV-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE21-1", "uniprot_id": "D3ZE21_RAT", "id": "D3ZE21-1", "name": "", "aln": "--------------MQTQT------ILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKIQQWDIGRHDFLES-APGLGMFVTVTN---NDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAVIVQAKDKVNEVAFTLRHLIEQIEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMK---HLKDFFIAKKLV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z7H5-1", "uniprot_id": "TMED4_HUMAN", "id": "Q7Z7H5-1", "name": "Transmembrane emp24 domain-containing protein 4", "aln": "------MAGVGAGPLRAMGRQA--LLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPS-TPGLGMHVEVKDP--DGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1MZX1-1", "uniprot_id": "A0A8M1MZX1_DANRE", "id": "A0A8M1MZX1-1", "name": "", "aln": "------MEMK--TLVSCVG-----FLLLFVWLSPSQALYFHIGETEKKCFIEEIPDETMVIGRYRTQLWDKQAGSFLPS-TPGLGMHVEIKDP--ETKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTVILIITGIWQMK---HLKSFFEAKKLV-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9BVK6-1", "uniprot_id": "TMED9_HUMAN", "id": "Q9BVK6-1", "name": "Transmembrane emp24 domain-containing protein 9", "aln": "MAVELGVLLVRPRPGTGLGRVMRTLLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPA-TPGLGMFVEVKDP--EDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BA5-1", "uniprot_id": "Q86BA5_DROME", "id": "Q86BA5-1", "name": "", "aln": "------------MRDQFIS-----LALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPS-SPGIGMHVEVRDS--DDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNST--AWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNLFHTCVYINEQCLCVCCLYIKKISALGLINDKINGLPDP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K5-1", "uniprot_id": "TMEDE_DROME", "id": "Q9I7K5-1", "name": "Transmembrane emp24 domain-containing protein eca", "aln": "------------MRDQFIS-----LALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPS-SPGIGMHVEVRDS--DDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNST--AWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMR---HLKSFFEAKKLV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05359-1", "uniprot_id": "ERP1_YEAST", "id": "Q05359-1", "name": "Protein ERP1", "aln": "---------------MLLTSLLQVFACCLVLPAQVTAFYYYTSGAERKCFHKELSKGTLFQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVHQKGSASGDLTFLASDSGEHKICIQPEAG--GWLIKAKTKIDVEFQVGSDEK--LDSKGKATIDILHAKVNVLNSKIGEIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMK---HLGKFFVKQKIL-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*:: . *.:*: :::.. * . :: : :* : : : .:*: : : : .::: : .:.* : * : .*:* **: .:: : . ::.::::**.. * .: : . * .:: :* :**. * ** ** :** .* ..:** . * ::: ::: * :: : : ", "identical_positions": 31, "similar_positions": 80, "identity": "11.65%" }, { "cls_id": "homologset.agr.SGD:S000002133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXN7-1", "uniprot_id": "PPM1K_MOUSE", "id": "Q8BXN7-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPA-CYFSTSEARCS--RFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMD-------------------LLPREKDLETVLTLAFLEIDKAFASYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHSVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6K136-1", "uniprot_id": "PPM1K_RAT", "id": "A6K136-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MLSTAFITLVRSGRNQVKKRVLLSSILLQDHRQMTPA-CYCSISEPRCS--RFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVTD-------------------LLPREKDLETVLTLAFLEIDKAFSSYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3J5-1", "uniprot_id": "PPM1K_HUMAN", "id": "Q8N3J5-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPT-CHSSTSEPRCS--RFDPDGSGSPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGK--RKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD-------------------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADAT-LLTSGTTATVALLRDG-------------IELVVASVGDSRAILCRK-GKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKL---------------HHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PNEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P874-1", "uniprot_id": "A0A8M1P874_DANRE", "id": "A0A8M1P874-1", "name": "protein-serine/threonine phosphatase", "aln": "MSVALLVRYATLSGSRVCSRAAFN--LTNAHQEDPRR-ALHTPSSPRFSNSRFDPDSSGRPTTWDSFG-IWDNRIDEPILLPSSIRYGKLIPKVNLSRVGSASQIGQ--RKENEDRYQMSQMTDNIMYFAVFDGHGGAEAADFCHKNMEKHIKD-------------------IAAEETNLEFVLTKAFLEVDKALARHLHFSADAS-VLSAGTTATVALLRDG-------------IELVVGSVGDSRAMMCRK-GKAVKLTVDHTPERKDEKERIRRSGGFITWNSLGQPHVNGRLAMTRSIGDFDLKATGVIAEPETKRISL---------------HHVHDSFLALTTDGINFIMNSQEICDVINQCHD----PKEAAQRISEQALQYG------SEDNSTIIVVPFGAWGKHKSSEVSFSFSRSFVSSGRFA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5Q7-1", "uniprot_id": "A0ACD6B5Q7_DANRE", "id": "A0ACD6B5Q7-1", "name": "protein-serine/threonine phosphatase", "aln": "-MSVSAVCFSR---------------LLRCARCVHPA-RCVRVPGVRWHTTRLDMDGSGRPATWDSFG-IWDNRIEEPILLPPSIRYGTPIPHISLSRVGCATLIGR--RRENEDRFQVSELTQNVLYFALFDGHGGAHAADYCHKHMEQNIRD-------------------CLEMETDLQTVLSKAFLEVDAALEEKLQIYGNAS-LMMVGTTATVALLRDG-------------IELVVGSVGDSRALLCRK-GKSRKLTDDHTPERKDEKHRIRQSGGFVTWNSVGQANVNGRLAMTRSIGDFDLKKSGVIAEPEITRTLL---------------QHAHDSFLVLTTDGVNFIMSNQEICDIINLCHD----PTEAANVIAEQALQYG------SEDNSTVIVVPFGAWGKHQNTDYTHDMSRNFASIGRWS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25646-1", "uniprot_id": "PDP2_YEAST", "id": "P25646-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MRLGNAYAYCKPSQNVGLKLDLLRGLPGYVGHATSRINRLENQDNYSIKMMRSWPNAYGSALNCSVFDGHGEKGAQLSQLLADKLCSSLDFPEPSWDKQDLKKLVQEYARRFPEGNYWKHKLSTFEKFYNKFIKNCNSKQELLLMKEGDSAILGQNGGRMIFDKMGNIIDKIALLTELDRLRLFYGFARFDLDQCCGLGTAAGSTASSIFLYPYDDPNAPIDEGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDGIAHALTTTHHINSSRERHRLSIDPSRLDPDAFGETRFLNNFANTRSFGDVAGKPYGISSEPDIFSFLVGNTLHLPRSERSKLPFNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKKATPQFVAEETIKFIQAIATKHSDNATCVVVRLSNWGNWPNVDRTGPQRETKLMNAQSNETKLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. * . . . *. :: : . **. .: . :*. . .. . . : . *: *..: ::: :: : : .. .. :. : . *. . * :::* . . *: :: . * : :* ::*:* .****: ::* : * . ** * : . *:.*: . : ::.*:... ..:* ***:**. * *: :**: : : .:.**.*.***:. : .**: *.:. : . :.: ::*::::: .**:* :** :. **: . : . .. .: ", "identical_positions": 55, "similar_positions": 127, "identity": "12.44%" }, { "cls_id": "homologset.agr.SGD:S000002135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1R9-1", "uniprot_id": "RL34_MOUSE", "id": "Q9D1R9-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTQKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49207-1", "uniprot_id": "RL34_HUMAN", "id": "P49207-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11250-1", "uniprot_id": "RL34_RAT", "id": "P11250-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVLPGRLRGVVAVRPKVLMRLSKTKKHVQQGLWWLHVRQVCPDRIKRAFLIEEQKIVVKVLKAQAQSQKAK---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZWJ7-1", "uniprot_id": "RL34_DANRE", "id": "Q7ZWJ7-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKTGKSPKSACGICPGRLRGIRAVRPQVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQTQKSK---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHE5-1", "uniprot_id": "Q9VHE5_DROME", "id": "Q9VHE5-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTLRRRLSYNTRSNKRRIVRTPGGRLVYQYVKKNPTVPR--CGQCKEKLKGITPSRPSERPRMSKRLKTVSRTYGGVLCHSCLRERIVRAFLIEEQKIVK-ALKSQREALVKPVKAPKAKPEPKKKPAAGAKGTKAGAGKVTKGGAGAKGAAGKKPGQKPAAG---KPRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBH8-1", "uniprot_id": "Q9VBH8_DROME", "id": "Q9VBH8-1", "name": "Large ribosomal subunit protein eL34", "aln": "MVQRLTLRRRLSYNTRSNKRRIVRTPGGRLVYQYVKKNPTVPR--CGQCKEKLHGITPSRPSERPRMSKRLKTVSRTYGGVLCHSCLRERIVRAFLIEEQKIVK-ALKSQREALVKPVKKVVEK-KPVKAAAKKPAGKAAGK-------PGAK-VAGKKPAPKGAPKGVVKSKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P87262-1", "uniprot_id": "RL34A_YEAST", "id": "P87262-1", "name": "Large ribosomal subunit protein eL34A", "aln": "MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPK--CGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIIRAFLIEEQKIVKKVVKEQTEAAKKSEKKAKK---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:* *** .*** *** :: :***. : :.** . *: ** *:*: . ** :** * *.: . :** *********** .:* * :: ", "identical_positions": 44, "similar_positions": 24, "identity": "25.29%" }, { "cls_id": "homologset.agr.SGD:S000002156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84098-1", "uniprot_id": "RL19_HUMAN", "id": "P84098-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84100-1", "uniprot_id": "RL19_RAT", "id": "P84100-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84099-1", "uniprot_id": "RL19_MOUSE", "id": "P84099-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5L3-1", "uniprot_id": "RL19_DANRE", "id": "Q6P5L3-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLVKDGLIIKKPVTVHSRARCRKNTLARRKGRHMGVGKRKGTANARMPEKLCWMRRMRILRRLLRRYREAKKIDRHMYHSLYLRAKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRTKTREARKRREERQQAKKEEIIKTLSKEDETKK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36241-1", "uniprot_id": "RL19_DROME", "id": "P36241-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSSLKLQKRLAASVLRCGKKKVWLDPNEINEIANTNSRQNIRKLIKDGLIIKKPVVVHSRYRVRKNTEARRKGRHCGFGKRKGTANARMPTKLLWMQRQRVLRRLLKKYRDSKKIDRHLYHDLYMKCKGNVFKNKRVLMEYIHKKKAEKQRSKMLADQAEARRQKVREARKRREERIATKKQELIALHAKEDEIAAKAATAGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX82-1", "uniprot_id": "RL19A_YEAST", "id": "P0CX82-1", "name": "Large ribosomal subunit protein eL19A", "aln": "MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRD----ALLKEDA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: *****:**: **:******** .***::***: ****:*:* *::*.*.***: * * :: ::*:*** * ****** :**:* :: *::* *:***** :**:: ***:*:** ** . ***.**:** *:*:* : **: *.* * ::***** * : **.** :* *:: **: ", "identical_positions": 100, "similar_positions": 49, "identity": "49.26%" }, { "cls_id": "homologset.agr.SGD:S000002157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11633-1", "uniprot_id": "NHP6B_YEAST", "id": "P11633-1", "name": "Non-histone chromosomal protein 6B", "aln": "--------------------------------------------------MAATKEAKQPKE-----PKKRTTRRK-KDPNAPKRGLSAYMFFANEN-RDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6A2H1-1", "uniprot_id": "A0A8I6A2H1_RAT", "id": "A0A8I6A2H1-1", "name": "", "aln": "MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKCEDMAKADKARYEREMKTYIPHKGETKKKFKDPNAPKRPPSAFFLFCSEY-RPKIKGEHPGLSIGDVAKKLGEMWTNTAADDKQPYGKMAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEKEDEDEEEEDDDE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06943-1", "uniprot_id": "HMGZ_DROME", "id": "Q06943-1", "name": "High mobility group protein Z", "aln": "-----------------------------------------------------------------------------MSGDRPKRPLSAYMLWLNET-REQIKKDNPGSKVTDIAKRGGELWRG--LKDKTEWEQKAIKMKEEYNKAVKEYEANGGTDSGAPKKRKKAAAKPAKKAKKKESSEEEEEDESE-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCZ5-1", "uniprot_id": "Q9VCZ5_DROME", "id": "Q9VCZ5-1", "name": "", "aln": "---------------------------------------------------------------------------MSDCGARPKKPMSAFMLWMNSTGRKHIKAEHPDFSVQEVSVKGGEMWRAMADEDKIVWQESATTAMAEYKEKLKQWNFPKEHRFSDTQCICS-------SNTNQCPTLFVYDTMDDSMTPICRKCLSKTRCLH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JIT5-1", "uniprot_id": "E1JIT5_DROME", "id": "E1JIT5-1", "name": "", "aln": "--------------------------------------------------------------------------MMSDYGARPKKPMSAFMLWMNSTGRKNIRAEHPDFSVQEVSVKGGEMWRAMADEHKIVWQESASKAMAEYKEKLEKWNAFKEHQTESFPHIYEAPLSSRFSKTNQRPTLFVYDSKDEAMAPICRTCFSKAKCFH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: **:::: .. * :: ::*. .. ::. ** * ..* : . * .*:. :. ", "identical_positions": 12, "similar_positions": 26, "identity": "5.77%" }, { "cls_id": "homologset.agr.SGD:S000002158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TAW2-1", "uniprot_id": "SERP2_MOUSE", "id": "Q6TAW2-1", "name": "Stress-associated endoplasmic reticulum protein 2", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTLR-PQEEKYPVG--PWLLALFVFVVCGSAIFQIIQSIRMGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6R1-1", "uniprot_id": "SERP2_HUMAN", "id": "Q8N6R1-1", "name": "Stress-associated endoplasmic reticulum protein 2", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTLR-PQEEKYPVG--PWLLALFVFVVCGSAIFQIIQSIRMGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6X1-1", "uniprot_id": "SERP1_HUMAN", "id": "Q9Y6X1-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R2C1-1", "uniprot_id": "SERP1_RAT", "id": "Q9R2C1-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1W5-1", "uniprot_id": "SERP1_MOUSE", "id": "Q9Z1W5-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38374-1", "uniprot_id": "YSY6_YEAST", "id": "P38374-1", "name": "Protein YSY6", "aln": "MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTWL-GILLFLLVGGGVLQLISYIL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *:** *..** : : .*. . *:. .* .** .:::*:: *..::*:*. * ", "identical_positions": 18, "similar_positions": 25, "identity": "26.09%" }, { "cls_id": "homologset.agr.SGD:S000002159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VXQ8-1", "uniprot_id": "Q9VXQ8_DROME", "id": "Q9VXQ8-1", "name": "DUF155 domain-containing protein", "aln": "-MNFARLRFGQMVLGGLRIPRQQTQTQWMMDRRRWLASEATS-SAAAPAQAASVPRTQTQPRVKPLPLAEERLESILSPIRTRIIRKKRLAIDELSALGFLNTRGYTTAEEYNLEDLQIALREQNLYETKRFFSTDN----------------LDVEQNVLFVAAKYP--TGQQPREIFFFREGSVVFWN--CSDIETNNVLSFLRAFERESYVSALVHGESEVMPYTYIPSTAVDVEGDLVAESSDFNVTSRAFFQN---GKFFVTADTDSFLYKYTFSNAMAQSIKLGMWEATLDRYIDSIEHLTEDLKRGRRLRISRAAMLRKTGELFALRHVINLSSDLLDAPDFYWDREELEALYLQVCSYFSISRRTKVMNEKINHCVELAELVSHNLNDAHHIRLEWMIIILIMVEVGFEVLHFVSDHSDSHKLEVLPLAAPAASIPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03441-1", "uniprot_id": "RMD1_YEAST", "id": "Q03441-1", "name": "Sporulation protein RMD1", "aln": "MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKSRASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYSQVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPKLFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGFTEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVKLSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILRININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKEQLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQH---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : .* * .:.. ::::: :.: * * *: : :* : *..*.*. . . .* . *. : . :::. : :*. . . . . : . : ::. .::* . :.* . *. : ** . *. :: * *.: .*: : .:* ..: . * ** * . ..* . * . : .: : .:** :* ..*:. * ..:: * ::*:*:***:*:.::* :*. *:. :.:.::: . :: :*: :::. **** ** *** ..:**:*:: *.. :**.:* . .*:.*.:*..::*:::: :* :::..:*..:*. **:::*:*: *** :.*:::* * *:: ", "identical_positions": 78, "similar_positions": 170, "identity": "17.53%" }, { "cls_id": "homologset.agr.SGD:S000002160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40630-1", "uniprot_id": "TFAM_MOUSE", "id": "P40630-1", "name": "Transcription factor A, mitochondrial", "aln": "MALFRGMWSVLKALGRTGVEMCAGCGGRIPSSISLVCIPKCFSS-MGSYPKKPMSSYLRFSTEQLPKFKAKHPDAKLSELVRKIAALWRELPEAEKKVYEADFKAEWKAYKEAVSKYKEQLTPSQLMGMEKEARQRRLKK-KALVKRRELILLGKPKRPRSAYNIYVSESFQEAKDDSAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWEEQMAEVGRSDLIRRSVKRSGDISEH--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00059-1", "uniprot_id": "TFAM_HUMAN", "id": "Q00059-1", "name": "Transcription factor A, mitochondrial", "aln": "MAFLRSMWGVLSALGRSGAELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKR-KAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKKQRKYGAEEC------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03435-1", "uniprot_id": "NHP10_YEAST", "id": "Q03435-1", "name": "Non-histone protein 10", "aln": "-----------------------------------------------------------MSVEEK---KRRLEELKDQNVVLGLAIQRSRLSVKRLKLEYGVLLERLESRIELDPELNCEDPLPTLASFKQELLTKPFRKSKTKRHKVKERDPNMPKRPTNAYLLYCEMNKERIRQNGSLDVTRDLAEGWKNLNEQDRKPYYKLYSEDRERYQMEMEIYNKKISNIDADDDKEENEQKIKNNEEGSSTKVADSKGGEDGSLVSSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *: * : : * ::: :* .*. . *: . : * .. : : . . : .:::* : ::: *: :: : . **** .** :* :. : :.. : : * ****. .::: * : .:*. **. **: ::::: ::. .* ... :: . ", "identical_positions": 29, "similar_positions": 70, "identity": "10.94%" }, { "cls_id": "homologset.agr.SGD:S000002161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AU37-1", "uniprot_id": "RD21L_MOUSE", "id": "A2AU37-1", "name": "Double-strand-break repair protein rad21-like protein 1", "aln": "-------MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISP---------KVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFEI--YNINEIDISEPLAQNQSRPEEITLREEYSNDLLFQAGSFG----DEPEILRRHSFFDD-NILMNSSG---LVVEHSSGSFAEEKSLFFDN--------GDGFGDEGAAGEMIDNLL-QDE-STFLEE--AYLNKEVSLPPELPSSIMVEPGNSD-----------DQCIPED------EEINEITLLSNEDEGFTLDPIDDLDIADRRRRKKRRLLVDPVKEISSKAMHRQLASFMDTLMVLDLAPPTQRLMMWKKRGGVDMLLSTATQDLINDELKMLFTKCF---LSSDYKLA---------KLTLKESVRKEVGNQQ-------------IAEPSVMGEPN--SHSELDQPQDWKDVTDESVGSFQENVNMN---------------------------VNSEQDILGMISPAVEGLSSMNGSLAQEN-----------------CPAELESSGSKQNTEAEKWNQRLFQTLN-VLREFNKMGMQSFSLKKLCRNSDRKQAAAKFYTLLILKKHRAIELSQSVPYADIIATVGPMFYKM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADQ7-1", "uniprot_id": "D4ADQ7_RAT", "id": "D4ADQ7-1", "name": "", "aln": "-------MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISP---------KVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFDI--YNTNDIDISEPLAQNQSRPEEITLREEYSTDLLFQTGSFG----DEPELLRRHSFFDD-NILMNSSG---LVVEHSSGSLTEEKSLFFDN--------GDGFGDEGAAGEMIDHLL-QDE-NTFFED--TYLNKEVFLPPEVPSSVMVEPGNSD-----------DHYIPED------EKINEITLISNEEEGFTLDPIDGLDIADRRKRKKRRLLIDPVKEISSKTMHKQLTSFMDTLMVLDLAPPTQRLMMWKKRGGVETLLSTATQDLINEDLKMLFANCF---LSSDYKLA---------KLTLKESLRKEVGNQH-------------ILDPSVVEEPN--SHSELGQPQDGKDVTDESMGSFQENINRN---------------------------INSKQDILEMISPAAEGFSLVSASSAQEN-----------------HPAELESSGSKQNTEAEKWNQRLFQTLN-ELREFNKMGMQFFSLIKLCRNSDRKQAAAKFYTLLILKKHRAIELSQSAPYADVIATVGPMFHKL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4I0-1", "uniprot_id": "RD21L_HUMAN", "id": "Q9H4I0-1", "name": "Double-strand-break repair protein rad21-like protein 1", "aln": "-------MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSP---------KVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFCPGLVDLPKENFEASYNAITLPEEFHDFDT--QNMNAIDVSEHFTQNQSRPEEITLRENFDNDLIFQAESFG----EESEILRRHSFFDD-NILLNSSG---PLIEHSSGSLTGERSLFYDS--------GDGFGDEGAAGEMIDNLL-QDDQNILLED--MHLNREISLPSEPPNSLAVEPDNSE-----------CICVPEN------EKMNETILLSTEEEGFTLDPIDISDIAEKRKGKKRRLLIDPIKELSSKVIHKQLTSFADTLMVLELAPPTQRLMMWKKRGGVHTLLSTAAQDLIHAELKMLFTKCF---LSSGFKLGR--------KMIQKESVREEVGNQN-------------IVETSMMQEPN--YQQELSKPQTWKDVIGGSQHSSHEDTNKN---------------------------INSEQDIVEMVSLAAEESSLMNDLFAQEIEY---------------SPVELESLSNEENIETERWNGRILQMLN-RLRESNKMGMQSFSLMKLCRNSDRKQAAAKFYSFLVLKKQLAIELSQSAPYADIIATMGPMFYNI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61550-1", "uniprot_id": "RAD21_MOUSE", "id": "Q61550-1", "name": "Double-strand-break repair protein rad21 homolog", "aln": "-------MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISP---------KVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTSASNLLLEPEQSTSNLNEKMNHLEY---EDQYKDDNFGEGNDGGILDDKLISNNDGG-IFDDPPALSEAGVMLPEQPAHDDMDEDDNGS-LGGPDSPDSVDPVEPMP------TMTDQTTLVPNEEEAFALEPID-ITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFFLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREEQQPQQQQPQPQRDVIDEPIIEEPSRLQDSVMEASRTTIEESAMPPPP-PQGVKRKAG-QIDPEPSIPP--------------QQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEEEEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EK71-1", "uniprot_id": "F7EK71_RAT", "id": "F7EK71-1", "name": "", "aln": "-------MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISP---------KVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTSASNLLLEPEQSTSNLNEKINHLEY---EDQYKDDNFGEGNDGGILDDKLISNNDGG-IFDDPPALSETGVMLPEQPAHDDMDEDDNGS-LGGPDSPDSVDPVEPMP------TMTDQTTLVPNEEEAFALEPID-ITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREEQQPQPQQQQAQRDVIDEPIIEEPSRLQDSVMEASRTNIEESAMPPPP-PQGVKRKAG-QVDPEPAIPP--------------QQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEEEEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60216-1", "uniprot_id": "RAD21_HUMAN", "id": "O60216-1", "name": "Double-strand-break repair protein rad21 homolog", "aln": "-------MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISP---------KVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEY---EDQYKDDNFGEGNDGGILDDKLISNNDGG-IFDDPPALSEAGVMLPEQPAHDDMDEDDNVS-MGGPDSPDSVDPVEPMP------TMTDQTTLVPNEEEAFALEPID-ITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQ----RDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPP-PQGVKRKAG-QIDPEPVMPP--------------QQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TEL1-1", "uniprot_id": "RA21A_DANRE", "id": "Q6TEL1-1", "name": "Double-strand-break repair protein rad21 homolog A", "aln": "-------MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISP---------KVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFTLNQSRVEEITMREEVGNISLMTDNDFGDFGMDDREMMREENAFG--DIIHESSAANLLLEAEPGPAHLPDKTPNLDY----DDFGDNNL-ENSDGGILMDKILSNEDGGGIFDDPPAITDS-VMMPQDHG-DDDDDFDNFSPAGGPDSPDS-GPVEPLPNTTDQTDQTEQTTLVPNEDEAFALEPID-ITVKETKAKRKRKLIVDSLKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNGRLLKMFTRCLTPLVPDELRKRRKGGEADSLEDFLKELENPEVPREE--VLGHR----SDVIDQTIMEEPSMLQASSMEGSRTALDESMMPPPSRQRGLKRKSLETLEKDAVLPPMGVLEQTLQPLDQSVLSHQLEMPQVELPPEDTTNLSRLIPELDLLDEKSKDKDK---DDSDEEGEEGQGGDQDQEERRWNKRTQQMLHGLQRVVAKTGAQSISLLELCRNNNKKQAAAKFYSFLVLKKQQAIDLTQTEPYSDIIAAPGPRFHIV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8E1-1", "uniprot_id": "Q1L8E1_DANRE", "id": "Q1L8E1-1", "name": "", "aln": "-------MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISP---------KVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFTLNQSRVEEITMREEVGNLSLLQENDFADFGMDDREMMREEGAFEV-DIIHGASASNLLLESESSSVQIADKTNHLEYDQYKDDFGDNPM-ESTEGGMLVDKLLSNEDGGGIFDDPPAIPEG-VMMPQDHGADDDDDFDNLSPAGGPDSPDS-GPVEPLP---TMTDQTEQTTLVHNEEEAFALEPID-ITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNSRLLKMFTRCLTPLVPDELRKRRKGGEADSLDEFLKDLENPEVPREE--ALNQQ----RDIIDQTILEEPSVLQASAMEGSRTTLDESVMPPPSGPRGQKRK---AQDGEPALP---MLEDDRS---SIVSTQHVSLPQVELPPEEPVNIAQLIPDLDLIGEKSKDKKD---DDDEEEEEEGQSGDQDQEERRWNKRTQQMLHGLQRVIAKTGAESISLLDLCRNNNKKQAAAKFYSFLVLKKQQAVELRQDEPYSDIIATPGPRFHII----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12158-1", "uniprot_id": "SCC1_YEAST", "id": "Q12158-1", "name": "Sister chromatid cohesion protein 1", "aln": "MVTENPQRLTVLRLATNKGPLAQIWLASNMSN-IPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNR---LNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQENSMERKVQGAAPWD----TSLEVGRRFSPDEDFEHNN--------LSSMNLDFDIEEGPITSKS-------WEEGTRQSSRNFDTHENYIQDDD---FPLDDAGTIGWDLGITEKNDQNNDDDDNSVE-----------------------QGRRLGESIMSEEPTDFGFD----LDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETENSESIASSN---TYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLP--------DPILKNFLSYESLKKRK----------IHNGREGSIEEPE--LNVSLNLTDDVISNAGTNDNSFNELTDNMSD-------------------------FVPIDAGLNEAPFPEENIIDAKTRNEQTT----------------IQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :::****:****:: .: :.:. *:: :: : :.* .. : ::*****.** *:**:* ::*.:**:* .::: *:.* * .. . * *::* .:: : : . : : : : :*: : : . *: *. . : : : . : : :: : ::: : : : :. . . : .. . :: * * :: : . : : *.:.* ..* : . ::: *:. . . :: * : :. : :.. . *: * .: : **. : . . . . . . : . * : .. : : : : . . .* :::*: *: :* * .. .: * * .:.:: * :. ", "identical_positions": 54, "similar_positions": 160, "identity": "7.91%" }, { "cls_id": "homologset.agr.SGD:S000002162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35434-1", "uniprot_id": "ATPD_RAT", "id": "P35434-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPAALLRHPGLRRLVLQARTYAQAAASPAP-AAGPGQMSFTFASPTQVFFDGANVRQVDVPTLTGAFGILASHVPTLQVLRPGLVMVHAEDGTTTKYFVSSGSVTVNADSSVQLLAEEVVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3D9-1", "uniprot_id": "ATPD_MOUSE", "id": "Q9D3D9-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPASLLRHPGLRRLMLQARTYAEAAAAPAP-AAGPGQMSFTFASPTQVFFDSANVKQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHTEDGTTTKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30049-1", "uniprot_id": "ATPD_HUMAN", "id": "P30049-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPAALLRRPGLGRLVRHARAYAEAAAAPAA-ASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2X6-1", "uniprot_id": "Q9W2X6_DROME", "id": "Q9W2X6-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "------------MSFVKNARLLAARGARLAQNRSYSDEMKLTFAAANKTFYDAAVVRQIDVPSFSGSFGILAKHVPTLAVLKPGVVQVVENDGKTLKFFVSSGSVTVNEDSSVQVLAEEAHNIEDIDANEARQLLAKYQSQLSSAGDDKAKAQAAIAVEVAEALVKAAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12165-1", "uniprot_id": "ATPD_YEAST", "id": "Q12165-1", "name": "ATP synthase subunit delta, mitochondrial", "aln": "MLRSIIGKSASRSLNFVAKRSYAEAAAASSG-------LKLQFALPHETLYSGSEVTQVNLPAKSGRIGVLANHVPTVEQLLPGVVEVME-GSNSKKFFISGGFATVQPDSQLCVTAIEAFPLESFSQENIKNLLAEAKKNVS-SSDAREAAEAAIQVEVLENLQSVLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * .* : :.: ** . :.::..: * *:::*: :* :*:** ****: * **:* * ...: *:*:*.* :*: **.: : * *. :: :. : * : : :: :.* *: * :*. * * .. :", "identical_positions": 37, "similar_positions": 53, "identity": "21.89%" }, { "cls_id": "homologset.agr.SGD:S000002164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61074-1", "uniprot_id": "PPM1G_MOUSE", "id": "Q61074-1", "name": "Protein phosphatase 1G", "aln": "-MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDN--ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-KLQKALQDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDDKDKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCQKVPPHTKSGIGTGDEPGPQGLNGEAGPEDPSRETPSQENGPTAKGHTGFSSNSEHGTEAGQISEPGTATGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEVEEEEDDSEECSEDEDGYSSEEAENEEDEDDTEEAEEDDDEE---MMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTVELQAESGKRKLEEALSTEGAEDTGNSDKKK-AKRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15355-1", "uniprot_id": "PPM1G_HUMAN", "id": "O15355-1", "name": "Protein phosphatase 1G", "aln": "-MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS--ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAKRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35182-1", "uniprot_id": "PP2C1_YEAST", "id": "P35182-1", "name": "Protein phosphatase 2C homolog 1", "aln": "-----MSNHSEILERPETPYDITYRVGVAENKNSKFRRTMEDVHTYVKNFASRLDWGYFAVFDGHAGIQASKWCGKHLHTIIEQNILADETRDVRDVLNDSFLAIDEEINTKLVG------------------------------------------------------------------------------------------------------------------------------NSGCTAAVCVLRWELPDSVSDDSMDLAQHQR-----------------------------------------------------------------------KLYTANVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVEQAGG-LIMKS--RVNGMLAVTRSLGDKFFDS---------LVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKDITEPNE----------AAKVLVRYALENGTT------DNVTVMVVFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8WY54-2", "uniprot_id": "PPM1E_HUMAN", "id": "Q8WY54-2", "name": "Protein phosphatase 1E", "aln": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAVEGEEEEEGAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVT---DERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKP---------YICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDS-----SMVAHKLVASARDAGSS------DNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSGAGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHRFRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRNRIRSSLPWRQNSWKGYSENMRKLRKTHDIPCPDLPWSYKIE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . . . : .. . : . . * :.: ... :: .* . ::. : . * .. ::. : * .* .***: :: . *::: : **.. * *:: ** : . **** * ::*::** .. : . . : . ..::::****:::.:. ::. ..:.. . .: .. *: . .:: **:* ::: : ", "identical_positions": 31, "similar_positions": 96, "identity": "3.98%" }, { "cls_id": "homologset.agr.SGD:S000002165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62191-1", "uniprot_id": "PRS4_HUMAN", "id": "P62191-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62192-1", "uniprot_id": "PRS4_MOUSE", "id": "P62192-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62193-1", "uniprot_id": "PRS4_RAT", "id": "P62193-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48601-1", "uniprot_id": "PRS4_DROME", "id": "P48601-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQNQS-AQGGAGEKKDDKDKKKKYEPPIPTRVGKKKRRAKGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLMMEDEFIRNQERLKPQDEKNEEERSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKESVLYRKKEGTPEGLYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40327-1", "uniprot_id": "PRS4_YEAST", "id": "P40327-1", "name": "26S proteasome regulatory subunit 4 homolog", "aln": "MGQGVSSGQDK--KKKKGSNQKPKYEPPVQSKFGRKKRKG-GPATAEKLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. * .:. **...::* *****: ::.*:**:: ** :* *** : * *:*:****::*****:*::*:**: *.* :** ::*:***:.:::::**.*:*:*.*******:****::.. .::**********: *********:**. :::*** **:**:*:***::*:* *:*:*****:.***************** ****************.**********************:**************:* *::*:** *:************:******************************.***********:****************** * ** .**::*: ****:*.*::**.*. *: :*********:*:******:*******:** ****::** *: .* * . *****", "identical_positions": 303, "similar_positions": 98, "identity": "68.86%" }, { "cls_id": "homologset.agr.SGD:S000002166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPX9-1", "uniprot_id": "APC11_MOUSE", "id": "Q9CPX9-1", "name": "Anaphase-promoting complex subunit 11", "aln": "MKVKIKCWNGVATWLW---------------VANDEN---CGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLNAQQVQQHCPMCRQEWKFKE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYG5-1", "uniprot_id": "APC11_HUMAN", "id": "Q9NYG5-1", "name": "Anaphase-promoting complex subunit 11", "aln": "MKVKIKCWNGVATWLW---------------VANDEN---CGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12157-1", "uniprot_id": "APC11_YEAST", "id": "Q12157-1", "name": "Anaphase-promoting complex subunit 11", "aln": "MKVKINEVHSVFAWSWHIPSTSDEDAANNDPIGNDEDEDVCGICRASYNGTCPSCKFPGDQCPLVIGLCHHNFHDHCIYRWLDTPTSKGLCPMCRQTFQLQKGLAINDAHVQKFVEIVSRRREEMIEEGVAEEFVDFDEPIRQNTDNPIGRQQVDTILDEDFLLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: :.* :* * :.***: ***** ::** **.**.***:**** * * * ** *** :**.: : ****** ::::: ", "identical_positions": 45, "similar_positions": 21, "identity": "27.27%" }, { "cls_id": "homologset.agr.SGD:S000002172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVA5-1", "uniprot_id": "D3ZVA5_RAT", "id": "D3ZVA5-1", "name": "", "aln": "--MKPAG-----------GRGGWS-WGGGKGGGK------GGDTG-SGAKGGFGTRTRGGGGGGRGRGRGGGGGGGGGGGGGGGGGGGD-----RQRRGGPGRNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVTENGE-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPAPKSSSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WS3-1", "uniprot_id": "FBLL1_MOUSE", "id": "Q80WS3-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "--MKPAG-----------GRGGWG-WGGGKGGSK------GGDTG-SGTKGGFGARTRGSSGGGRGRGRGGGG--------GGGGGGGD-----RQRRGGPGKNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVMENGE-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPPPKSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHQ2-1", "uniprot_id": "FBLL1_HUMAN", "id": "A6NHQ2-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "--MKSAASSRGGGGGGR-GGGGWGSWGGGRGGGGGAGKGGGGDGGGQGGKGGFGARARGFGGGGRGRGRGGGD---------GKDRGGG-----GQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGV-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35550-1", "uniprot_id": "FBRL_MOUSE", "id": "P35550-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRG---GGGGRGGG-FQSGGNRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22509-1", "uniprot_id": "FBRL_RAT", "id": "P22509-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRG---GGGGRGGG-FQSGGGRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKAKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22087-1", "uniprot_id": "FBRL_HUMAN", "id": "P22087-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGG----RGGFGGGRG-RGGGFRGRGRGGGGGGGGG---GGGGRGGGGFHSGGNRGR--GRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1V3-1", "uniprot_id": "FBRL_DROME", "id": "Q9W1V3-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "-MGKPGFSPRGGGGGGGGGGGGFRGRGGGGGGGGGGFGGGRGRGG-GGDRGGRGGFGGGRGGGGRGGGGGGGRGAFGGRG-GGGGRGGG-GRGGGGRGGGGRGGGAGGFKGGKTVTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVETNGE-------KIEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRPPPKQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15646-1", "uniprot_id": "FBRL_YEAST", "id": "P15646-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "MSFRPGSRGG--------SRGGSRGGFGGRGGSR------GGARG--GSRGGFG-GRGGSRGGARGGSRGGFGGR-------GGSRGGA-----RGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. ** * *. * * :** * ** ** . ** * . ** . :. * :***** **:* ** ** *** *:.** .****:*::: . * ***.**********.::**::::.: * ***********:******::**:*:*********.**:*:.:****.****::****** *****:.*** :********* **:***:: **:: * .:*****.*****...*:*** **:*:: :.:** ************.:*** * ", "identical_positions": 165, "similar_positions": 66, "identity": "46.09%" }, { "cls_id": "homologset.agr.SGD:S000002173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1Y9-1", "uniprot_id": "D4A1Y9_RAT", "id": "D4A1Y9-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLE--RKRELLFQGLPQFTMKNNTRNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIYDVKQKFHKACPKW-YPSRIGLQLEYGGPYLKDYITIQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLR--SSYIYDVKESFRWPRHTVVHLACFCHCI-HYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAY--------YINHPRYTPPSFGNRQIIVSAI-NFLMCEAGNHFINTVLAHP----SHTGS-NACFPSPTYNPFTWMFFLVSCPNYTYEIGTWISFTIMTQT-LPVGIFTMLMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPFIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ1-1", "uniprot_id": "TECRL_MOUSE", "id": "Q8BFZ1-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLE--RKRELLFQGLPQSTMKNNARNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIHDVKQKFHKACPKW-YPSRIGLQLEYGGPYLRDYITVQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLR--SSYIYDVKESTRWPRHPVVHLAFFCHCI-HYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAY--------YINHPRYTPPSFGNRQVIVSAI-NFLFCEAGNHFINTVLAHP----NHTGS-NACFPSPNYNPFTWLFFLVSCPNYTYEIGSWISFTVMTQT-LPVGIFTILMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYJ1-1", "uniprot_id": "TECRL_HUMAN", "id": "Q5HYJ1-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKW-YPSRVGLQLECGGPFLKDYITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLR--IPCIYDGKESARRLRHPVVHLACFCHCI-HYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAY--------YINHPLYTPPSFGNRQITVSAI-NFLICEAGNHFINVMLSHP----NHTGN-NACFPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTVMTQT-LPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIPFIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CY27-1", "uniprot_id": "TECR_MOUSE", "id": "Q9CY27-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "--------------------------------------------------------MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTHPQW-YPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR--VPFIYGRKYDFTSSRHTVVHLACMCHSF-HYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAY--------YINHPLYTPPTYGVQQVKLALA-VFVICQLGNFSIHMALRDL----RPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAILTQC-VPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64232-1", "uniprot_id": "TECR_RAT", "id": "Q64232-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "--------------------------------------------------------MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTHPQW-YPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR--VPFIYGRKYDFTSSRHTVVHLACMCHSF-HYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAY--------YINHPLYTPPTYGVQQVKLALA-IFVICQLGNFSIHMALRDL----RPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQC-VPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZ01-1", "uniprot_id": "TECR_HUMAN", "id": "Q9NZ01-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "--------------------------------------------------------MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQW-YPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR--VPFIYGHKYDFTSSRHTVVHLACICHSF-HYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAY--------YINHPLYTPPTYGAQQVKLALA-IFVICQLGNFSIHMALRDL----RPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQC-LPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7E4-1", "uniprot_id": "A0A8M1Q7E4_DANRE", "id": "A0A8M1Q7E4-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "-----------------------------------------------------MSRTIFFEVEILDSKTKEQLCFLDKVEPHSSIGDIKSLFHKSYPKW-YPARQALRLDPKNKALRDDDILQNLPAGTSVTMYFRDLGPQLGWTMVFLAEYIGPLLIYLLFYVR--VPYIYNHKYTFTSSTHPVVSLACACHSF-HYIKRLFETIFVHRFSHGTMPLRAIVKNCVYYWGFAAWLAY--------YINHPLYTPPSYGEIQVNYALI-IFVLCEAGNFSIHWSLNSL----KCEGSKCRRFPHPSKNPFTWLFFFVSCPNYTYEVGAWVGLSIMTQC-VPVALFTFVGFIQMTIWAKGKHQIYVREFKNYPNLRMPILPFIL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL3-1", "uniprot_id": "Q9VZL3_DROME", "id": "Q9VZL3-1", "name": "very-long-chain enoyl-CoA reductase", "aln": "-----------------------------------------------------------MELEILNAKNSKPYGKVKVPSGATPIGDLRALIHKTLKQTPHANRQSLRLELKGKSLKDTDTLESLSLRSGDKIYVKDLGPQIGWKTVFLAEYAGPLIVYLIFYFR--PELVYGKAASLPIS--LTTHIAAGCYTV-HYVKRLLETIFVHRFSHATMPLRNLFKNCTYYWGFTAYVSY--------HVNHPQFTSPCMCT--VWGALG-AFALCELGNFSVHIALRNL----RPPGTKVRKIPVADGNPLTKLFDLVSCPNYTYEIGAWVSFSVLTSC-LAAYLFAFAGAFQMTIWALAKHRNYKKEFKDYPRQRRSIFPFVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99190-1", "uniprot_id": "TECR_YEAST", "id": "Q99190-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "-----------------------------------------------------------MPITIKSRSKGLRDTEIDLSKKPTLDDVLKKISANNHNISKYRIRLTYKKESKQVPVISESFFQEEADDS-MEFFIKDLGPQISWRLVFFCEYLGPVLVHSLFYYLSTIPTVVDRWHSASSDYNPFLNRVAYFLILGHYGKRLFETLFVHQFSLATMPIFNLFKNCFHYWVLSGLISFGYFGYGFPFGNAKLFKYYSYLKLDDLSTLIGLFVLSELWNFYCHIKLRLWGDYQKKHGNAKIRVPLNQG-----IFNLFVAPNYTFEVWSWIWFTFVFKFNLFAVLFLTVSTAQMYAWAQKKN-------KKYHTRRAFLIPFVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . :. : :: : : * : : : . .:. . : :: *** *:.* **: ** **:::: :** : . . . ** : *:**:***:.* . *: :. .* .** ::. ::: . * :. : * :.: *. : * *. .* :* :. .****:*: :*: ::.: . : . :* ** ** *: ..* : ::*:::", "identical_positions": 49, "similar_positions": 86, "identity": "12.83%" }, { "cls_id": "homologset.agr.SGD:S000002175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8S5-1", "uniprot_id": "D4A8S5_RAT", "id": "D4A8S5-1", "name": "Cell division cycle 7-related protein kinase", "aln": "------------------------------------------------------------MEEPMAFSPLRGCDRCPADDS-------------LKKYEQSVKLSG--------------------IKRDIEELCEAVPQLVSVFKIKDKIGEGTFSSVYLA-------TAQLQEGREE----KIALKHLIPTSHPVRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMFNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKCHGVIG--HKGPLSRPAPKNVDQHITTKTSVKRSYANAQIHIKQGKDGKEGSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAEKLIKQSKTVDIMSRKLATKKMAVSTKAVN-SSMRDSARSCPAALTCDCYGTDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSILCS------KEVPAQDLRTLCERLRGPDSANPKSAVDPPGNTGHHPAASESTDHKAP-HAPASPAQHSEDSLYKRGSGGGRRHPRDRTANPEGWDSVPDDAYDLLDKLLDLNPASRITAEAALVHPFFKDVC----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H0-1", "uniprot_id": "CDC7_MOUSE", "id": "Q9Z0H0-1", "name": "Cell division cycle 7-related protein kinase", "aln": "------------------------------------------------------------MEEPMAFSSLRGSDRCPADDS-------------LKKYEQSVKLSG--------------------IKRDIEELCEAVPQLVNVFKIKDKIGEGTFSSVYLA-------TAQLQEGHEE----KIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVG--HKGLLSRPAPKTVDQQCTPKTSVKRSYT--QVHIKQGKDGKERSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAEKLIKQSKTVDIISRKLATKKTAISTKAMN-SVMRETARSCPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS------KEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKAS-RVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFFKDMCS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00311-1", "uniprot_id": "CDC7_HUMAN", "id": "O00311-1", "name": "Cell division cycle 7-related protein kinase", "aln": "----------------------------------------------------MEASLGIQMDEPMAFSPQR--DRFQAEGS-------------LKKNEQNFKLAG--------------------VKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLA-------TAQLQVGPEE----KIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITG--NKIPLSGPVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCS------KEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Y1-1", "uniprot_id": "CDC7_DROME", "id": "Q9W3Y1-1", "name": "non-specific serine/threonine protein kinase Cdc7", "aln": "MADR---VMCQELATPGSHYRRPK--TGVPSTNVVYANG----GGSWRAAPRQTQRLPRQTVQQYATGTPATGSAGRHSGR--------AFATAGATEEQTVEFNG-AAVMGLPATPRTTKQARNKSEEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLG-------TLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLS------QRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEP--------------------LDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAEEAEQ----TEQDQLANGTPRKMRRQRYQ--SHRTVAASQE-QVKQQVALDLQQAAINKL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ90-1", "uniprot_id": "CDC7B_DROME", "id": "Q9VJ90-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDKKEVQHHRSQQAMTKSLYAIGMGLLGKSATNMDCANTNLESAGKSSSTNYNRNRFYNERFVPMASGTMPSVSGTNHHSRHQQLLLQQAPKCTADLNEKLVKINRQNANKELSTIQAKDMQSVDKNEEALKELQESIPEINKIFDVHCRIGSGTFSTVLLG-------TLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQRIADDGSVVQSSDLSSREVFSILRDLENG---------------RSVTLTDGNS------AQAEAEDYMARRRMRALGGGGSVERAVTGP----------------PSIQKLREQAGGHLTKKDVANQRADTMR-----LLNRLRLVSPNADPNNYVVSTNTS-----------------------KKEMHASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLA------QKVNTLDLRRVCMRFRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHNLER--------------------YDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFSDQHRITPGIPLHQQQLIMHQQQHIMQHQQHLQRSRETLPSSAARTLKAFVCYPMEITSTASQAAGNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06243-1", "uniprot_id": "CDC7_YEAST", "id": "P06243-1", "name": "Cell division control protein 7", "aln": "---------------------------------------------------------------------------------------------MTSKTKNIDDIPP-------------------EIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISS-----------------------------------------------------QNDYDNYANTNHDGGYSMRNHEQFCP-------------------CIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNET-------------------------------RRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVAFETFGFLQQELHDRMSIEPQLPDPKTNMDAVD-----------AYELKKYQEEIWSDHYWCFQVLEQCFEMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDE------------------DDVVSSSEADLLDKDVLLISE------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: :. : .* :* : . :.: :**.****:* . * : : .*:*: *. * ** **: : * ..* : . * . :*: *: * : : . ::.*: :*: **: :*. .::***:**:*:*:* . . * *****: . . . :: : :. : .. . :: * **** *:*.**** : *:* :*:*:.***:**::. .*:::: .* :* :: .: * : * . . : . . .*: . : . . :: : .:::*.: ::::* .* :** * .**. ", "identical_positions": 77, "similar_positions": 122, "identity": "10.09%" }, { "cls_id": "homologset.agr.SGD:S000002176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK85-1", "uniprot_id": "TMED1_RAT", "id": "Q5BK85-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "----MMAAGAAVALALWLL--LPAVGV-GEAGPP-------PIQDGEFTFLLPAGRKQCFYQSAPAN-ASLETEYQVIGG--AGLDVDFTLESPQGV---LLVSESRKADGVHTVEPTEAGDYRLCFD--NSFSTISEKLVFFELIFDSFQDEEE-VEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRFFHDKCPVPT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V009-1", "uniprot_id": "TMED1_MOUSE", "id": "Q3V009-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "----MMAAGAAVALALWLL--LPAVGV-GEAGPP-------PIQDGEFTFLLPAGRKQCFYQSAPAN-ASLETEYQVIGG--AGLDVDFTLESPQGV---LLVSESRKADGVHTVEPTEAGDYRLCFD--NSFSTISEKLVFFELIFDSFQDEEE-VEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRFFHDKRPVPT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13445-1", "uniprot_id": "TMED1_HUMAN", "id": "Q13445-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "----MMAAGAALALALWLL--MPPVEV-GGAGPP-------PIQDGEFTFLLPAGRKQCFYQSAPAN-ASLETEYQVIGG--AGLDVDFTLESPQGV---LLVSESRKADGVHTVEPTEAGDYKLCFD--NSFSTISEKLVFFELIFDSLQDDEE-VEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CXE7-1", "uniprot_id": "TMED5_MOUSE", "id": "Q9CXE7-1", "name": "Transmembrane emp24 domain-containing protein 5", "aln": "-----MGGRMWLPFPVLLLSALPAALLRGAAGFT-------PSLDSDFTFTLPAGRKECFYQPMPLK-ASLEIEYQVLDG--GELDIDFHLTSPEGR---TLVFEQRKSDGVHTIE-TEDGDYMFCFD--NTFSTISEKVIFFELILDNMGEEVQGQEDWKKYITNTDVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLKSLFEDKRKSRT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXN3-1", "uniprot_id": "TMED5_RAT", "id": "Q6AXN3-1", "name": "Transmembrane emp24 domain-containing protein 5", "aln": "-----MGVRMWLPFPMLLLSALPATLLSGAAGFT-------PSLDSDFTFTLPAGQKECFYQPMPLK-ASLEIEYQVLDG--GELDIDFHLASPEGR---TLVFEQRKSDGVHTVE-TEDGDYMFCFD--NTFSTISEKVIFFELILDNMGEEVEGQEDWKKYITNTDVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLKSLFEDKRKSRT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78IS1-1", "uniprot_id": "TMED3_MOUSE", "id": "Q78IS1-1", "name": "Transmembrane emp24 domain-containing protein 3", "aln": "--------MVHEAPHASSFQMLLQLLLLLLLRAE-------PLRSAELTFELPDNAKQCFHEEVEQG-VKFSLDYQVITG--GHYDVDCYVEDPRGN---VIYRETKKQYDSFTYKTEAKGVYRFCFS--NEFSTFSHKTVYFDFQVG----------DEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPVNRAVHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY25-1", "uniprot_id": "TMED3_RAT", "id": "Q6AY25-1", "name": "Transmembrane emp24 domain-containing protein 3", "aln": "--------MGNEVPRASSFQMLMLLLLLLLLRAE-------RLRGAELTFELPDNAKQCFHEEVEQG-VKFSLDYQVITG--GHYDVDCYVEDPMGN---IIYRETKKQYDSFTYKTEVKGVYRFCFS--NEFSTFSHKTVYFDFQVG----------DEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPINRAVHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YZZ5-1", "uniprot_id": "D3YZZ5_MOUSE", "id": "D3YZZ5-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "--MPRPGSAPRWAAAAGRWGCRLLA--LLLLLPA-------PSGGSEITFELPDNAKQCFYEDITQG-TKCTLEFQVITG--GHYDVDCRLEDPDGK---VLYKEMKKQYDSFTFTASRNGTYKFCFS--NEFSTFTHKTVYFDFQVG----------EDPPLFPSE-NRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSVGQVFLLKSFFSDKRTTTTRVGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTX0-1", "uniprot_id": "TMED7_RAT", "id": "D3ZTX0-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "--MPRPRSATCWAAAAGRWSCRLLALLLLLLLPG-------PSGGSEITFELPDNAKQCFYEDITQG-TKCTLEFQVITG--GHYDVDCRLEDPDGK---VLYKEMKKQYDSFTFTASKNGTYKFCFS--NEFSTFTHKTVYFDFQVG----------EDPPLFPSE-NRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63524-1", "uniprot_id": "TMED2_RAT", "id": "Q63524-1", "name": "Transmembrane emp24 domain-containing protein 2", "aln": "--------------------MVTLAELLVLLAAL-------LATASGYFVSIDAHAEECFFERVTSG-TKMGLIFEVAEG--GFLDIDVEITGPDNK---GIYKGDRESSGKYTFAAHMDGTYKFCFS--NRMSTMTPKIVMFTIDIG----------EAP--KGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q3-1", "uniprot_id": "TMED2_MOUSE", "id": "Q9R0Q3-1", "name": "Transmembrane emp24 domain-containing protein 2", "aln": "--------------------MVTLAELLALLAAL-------LATASGYFVSIDAHAEECFFERVTSG-TKMGLIFEVAEG--GFLDIDVEITGPDNK---GIYKGDRESSGKYTFAAHMDGTYKFCFS--NRMSTMTPKIVMFTIDIG----------EAP--KGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VRU2-1", "uniprot_id": "Q9VRU2_DROME", "id": "Q9VRU2-1", "name": "", "aln": "MQLTWQRDQINLVLPIALICCCLLIDVTSAQEAQQPWYENLPAVAMDYKVHIDAGKEDCYHQYVKAG-ATFYVSFSVVRG--GDGMAGFAVRNPAGE---VVKPYQWQATADYTDQVSPGGYYSVCID--NQFSRFAGKLVNIYITVVKY-------DAWDKYAKEIEQLQLNMQNFTATVGTVERNINDMMGYQAHSRHRESRDYALLLDNNAYIQTFSISQIVVILITCSVQVFFVRKLFEVKSSSKSRI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZJV9-1", "uniprot_id": "D3ZJV9_RAT", "id": "D3ZJV9-1", "name": "", "aln": "----MFALLLEAGLVVLSLVTSAKSQRTDPLHGSKDQPLLRGADRHDFAIVVHPGNTECFWQFADQM-GYLYFSYEVQRT--LGMSHDRHIVATAHTPQGFLIDTSQDVRGQINFATQETGFYQLCLK--NEQNRFSSIQVYLNFGVFYEG------PEMDHKQSQRKQLNDTLDAIEDSTRRVQNHVFHMWRFYNSARMRKVADFFLLQSNYSYVNWWSTAQSLAIVLSGVLQLYFLKRLFTISTDTKKPRC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12403-1", "uniprot_id": "ERP3_YEAST", "id": "Q12403-1", "name": "Protein ERP3", "aln": "---------------MSNLCVLFFQFFFLAQFFA---------EASPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGESNDFDVNYEIFAPDDKNK-PIIERSGERQGEWSFIGQHKGEYAICFYGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFRESRKHNV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* : * . : . : . . * * .*: : . : . . : : . : . : :* :. *: :. :* ", "identical_positions": 8, "similar_positions": 30, "identity": "3.15%" }, { "cls_id": "homologset.agr.SGD:S000002177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2B8V1-1", "uniprot_id": "A0A8M2B8V1_DANRE", "id": "A0A8M2B8V1-1", "name": "Oxysterol-binding protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNEDEFYDAVTG-------------LDSD---ESCEGTSEASFKD-----------------------------------------------AVVYDGAQKN-----------------------------NGAVPQENGIKK--------------------------------RRSCLPAPMFSRNDFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRLTEYMEHTYLLQKACLQNDSIERMQTVAAFAVSAVASQWDRTGKPFNPLLGETYELTRE-DQGFRLISEQVSHHPPISAFHTESLMGDFVFHGSIYPKLKFWGKSVEAEPKGTITLELHKHKEA----YTWTNPFCCVHNVILGKLWIEQYGTVEIINHSTGE--KCVLNFKPCGMFGKELH-RVEGYIQDKSKKKRCVIYGKWTECMWSVDPQAYEAHRKLEKKGTTDTKKQKQQEEPEAVNEDADEMPEVQ-ETVAVIPGSTLLWRISSRPPLSAEMYNFTNFAMALNELEPGMEGVLAPTDCRLRPDIRAMENGNMDEASREKERLEEKQRAARKERAK--------------------------------------------------------------------------------------NEEEWSTRWFQLGTNPYTGSQDWLYTGGYFDR----KYRNCPDIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K4M9-1", "uniprot_id": "OSBL1_RAT", "id": "Q8K4M9-1", "name": "Oxysterol-binding protein-related protein 1", "aln": "------------------------------------------------------------------------------------------------------MNTEAEQQLLHHARNGNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQDLLKAGAKVNMLNDMGDTPLHRAAFTGRKELVMLLLEYN---ADTTVVNGSGQTAKEATHDKEIRQMLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCS------------DQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAHGTEMKHILVGNKV----VHKALKRFEGPLWKSSRFFGWKLFWVVLEHGVLSWYRKQPDAVHNSYRQGCKHLTQAVCTVKPTDGCLFSVRCFDDTVHGFRVPKNSLQQSREKWL------------------------------------------------EAIEEHSAYSTHYCS-----------------QDQVTDDEEEDVASAMDLKESLARAQTCQQRLDREIYNFLKMIKECDVAKDMLPSFLQKADVLSEASRETCVALSDCLNLFTKQEGVRNFKLEQEQEKNKILSEA------------------------------------------------------------------------------------LETLATEHHELERSLVEGSPPVSILSEDEFYDALSG-------------SESEGSLTCLEAVTARAFEE-----------------------------------------------NEVPANSGKHRMSEG---------------------KDCGGGDALSNGIKK--------------------------------HRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSFSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRD-DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEA----YTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGD--KCVLNFKPCGLFGKELH-KVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKTSKQAS----TSEESDEMPVPDSESVFVIPGSALLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMETVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSK--------------------------------------------------------------------------------------SEEDWKTRWFHQGPNPYSGAQDWIYSGSYWDR----NYFNLPDIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1P3-1", "uniprot_id": "OSBL2_HUMAN", "id": "Q9H1P3-1", "name": "Oxysterol-binding protein-related protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGEEEFFDAVTG-------------FDSDN--SSGEFSEANQKVT-----------------------------------------------GMIDLDTSKNNRIG-----------------------KTGERPSQENGIQK--------------------------------HRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIRE-DLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEA----YTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH--KCVLHFKPCGLFGKELH-KVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQ-ETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAK--------------------------------------------------------------------------------------EEAEWQTRWFYPGNNPYTGTPDWLYAGDYFER----NFSDCPDIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q712-1", "uniprot_id": "A0A8M1Q712_DANRE", "id": "A0A8M1Q712-1", "name": "Oxysterol-binding protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTELVVRTLP--------------------------------------------------------------------------------SPS-GVQGPGP-------------DTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTITLATVHIEVGDT----CHFVLTSG-GRSYHLKAYSEGECQRWVSALQQAKANATHMMP-------------------HSDDSG--DEGPLAQPDR------ALIQGALKTLV------------------------------------------------SKLEDLSTCNELIGK-----------------HGAALQRSLSELEDLRAPTDGTDKLKTVNERATLFRITSNAMINACQDFVDLAEGHSRRWQRALQYEREQRHHLEETIEQLAKQHNSLERAWRES---------------------------------------------------------------------------------------------------PSTLNQAAEGTLEGESSEENEDIEFFDAMED---------------SPAFITVPADNHSQHRLL----------------------------------------------SSNQSVTSGSLSSN-----------------------WSQDD------NDGSGSYLR---------------------------RGRRRRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVI-SQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNH----YVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKD--TCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDEKMESAKIIESS-HACGGSEGKQK--------------------------TVYQTLPPKLLWKKYPLPENAENMYYFSSLALTLNELED----GIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQRLERRKRDAQANLA----LEEGKE------------------------------------------------------------------------VETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q8S0-1", "uniprot_id": "A0A8M9Q8S0_DANRE", "id": "A0A8M9Q8S0-1", "name": "Oxysterol-binding protein", "aln": "-------------------------------------------------------------------------------------------------------MGRVAAP-----CNNGPGRIVSFLTAVPCLSC------------------KQQQQRRQQHHQSAAVERGRRRMSEQGKSAAS--------------------------------------------------------------------------------TPASGTPAPGS-------------DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDA----CNIVLSSG-GRTYHLKASTEVERQRWVTALELAKAKAIRMMNDQSDNGH----TASLTHCYQSDDSA--DEEPTSQSDH------SEIQGTLKTLA------------------------------------------------SKLDDLSTCNELIAK-----------------HGAALQRSLSELETLRVPLEGGEKIKAVNERATLFRITSNAMINACRDFLELAESHSRRWQRVLQHEREQRTHLEETIEQLAKQHNSLERAWREAPAHAVNTPDT-----------------------------------------------------------------------------------------PTTDTGVSERPRKEEASDEDEDTEYFDAMED---------------SPAFITVTATDPSQHRRS----------------------------------------------QSNLSGASGGQPSD-----------------------WNQDDNCSVSSNDFSGKELQPR-------------------------RKRRSRISEKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCENSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVV-SQRGWSLWQEITIASKFRGKYLSIMPLGAIHLQFHASGNH----YVWRKVTSTVHNIIVGKLWIDQSGDIDIVNHRTKE--TCQLKFSPYSYFSREVPRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSS-RGSSSSEGKQK--------------------------TVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEEED----GVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRREAEASRA----IDEGED------------------------------------------------------------------------FEGYKPLWFHQTTDEMTGENIFVYKGGYWEAKDRQDWSMCPEIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q969R2-1", "uniprot_id": "OSBP2_HUMAN", "id": "Q969R2-1", "name": "Oxysterol-binding protein 2", "aln": "-------------------------------------------------------------------------------------------------------MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEPEP-GAGQPSELLQ---GSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS----CGILLTSG-ARSYHLKASSEVDRQQWITALELAKAKAVRVMN------------------THSDDSGDDDE-ATTPADK------SELHHTLKNLS------------------------------------------------LKLDDLSTCNDLIAK-----------------HGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANP--------------------------------------------------------------------------------------------SKSFIEGSLLTPKGEDSEEDEDTEYFDAMED---------------STSFITVITEAKED--------------------------------------------------SRKAEGSTGTSSVD-----------------------WSSADNVLDGASLVPKGSSK---------------------------VKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVF-SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNH----YVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTND--RCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSS-PSSPSSDGKQK--------------------------TVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEE----GVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKE------------------------------------------------------------------------ADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHG4-1", "uniprot_id": "D3ZHG4_RAT", "id": "D3ZHG4-1", "name": "Oxysterol-binding protein", "aln": "-------------------------------------------------------------------------------------------------------MGKAAALSRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSTLGSGPAPKPQFQPVQAPERELLSEQVCQPISE--PRSEPGSQTTFVPQPLGAGQESESL----GLWPGS--------GPNTKASPELPSPPRSTAESL-PKPESKAGPKTQSVLRPGQSKTSAGSPVSGT----SVPMVSPPLDSYKGWLFKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLASAHFETEDS----CGILLCNG-ARTYHLKASSEVDRQQWITVLELAKAKAIRVMN------------------TQSDDSGDDDEEPAAPADN------SDLHHTLKTLS------------------------------------------------LKLDDLGTCNDLIAK-----------------HGAALQRSLNELDSLKIPSESGEKLKVVNERATLFRITSNAMINACKDFLELAEIHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPASS--------------------------------------------------------------------------------------------SKSFSEGSFLTSKGENSEEDEDTEYFDAMED---------------STSFITVITEAKEDRVNLLSSSPRVLGSIQSTASCPSPEALAAWLSHTAHPQAPRARAHQPQCPCRKPEGGPGTTSVD-----------------------WTSADNVLDGASFMPKDSCK---------------------------VKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVF-SKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNH----YVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKD--RCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSS-PS---SDGKQK--------------------------TVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEE----GVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLNRRRRLESCTAG--CGGEEEKE------------------------------------------------------------------------SDGYSPLWFEKRLDPLTGEMACIYKGGYWEAKEKKDWHMCPNIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3B7Z2-1", "uniprot_id": "OSBP1_MOUSE", "id": "Q3B7Z2-1", "name": "Oxysterol-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------MAATELRGVVGPGPAAIAAPGGGGAGPPAVGGGGGRGDAGPGPGVAA--ATAATAGGPGPGAG-----GVAAGGPGSAP---------------------------------------------------------------------------------PAAGSGGSGA---------GGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDS----CNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLA-------------------ESDDSG--DEESVSQTDK------TELQSTLRTLS------------------------------------------------SKVEDLSTCNDLIAK-----------------HGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANPPG------------------------------------------------------------------------------------------SAGSGKDQCCSGKGDMSDEDDENEFFDA-------------------PEIITMPEN-LGHKRTG-----------------------------------------------SNISGASSDV---------------------------SLDEQYKHQLEETK--------------------------------KEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAE-SKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHH----YTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGD--KCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAAS--GENGGDARQR--------------------------GHEAEDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEG----GTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAAKAT----EDG---------------------------------------------------------------TPH---------DPYKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGSCPDIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A9D8-1", "uniprot_id": "D4A9D8_RAT", "id": "D4A9D8-1", "name": "Oxysterol-binding protein", "aln": "----------------------------------------------------------------------------------------------------------MAATELRGVVGPGPAAIAAPSGGGAGPPAVGGGGGRGDAGPGSGVAG--ATAATAGGPGPGAG-----GVAAGGPGSAP---------------------------------------------------------------------------------PAAGSGGSGA---------GGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDS----CNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLA-------------------ESDESG--DEESVSQTDK------TELQNTLRTLS------------------------------------------------SKVEDLSTCNDLIAK-----------------HGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANTPG------------------------------------------------------------------------------------------STGSGKEQCCSGKGDMSDEDDENEFFDA-------------------PEIITMPEN-LGHKRTG-----------------------------------------------SNISGASSDI---------------------------SLDEQYKHQLEETK--------------------------------KEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAE-SKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHH----YTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGD--KCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQPAS--GENGGDARQR--------------------------GHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWEG----GTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKAT----EDG---------------------------------------------------------------TPY---------DPYKALWFERKKDPVTKELTHVYRGEYWECKEKQDWGSCPDIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22059-1", "uniprot_id": "OSBP1_HUMAN", "id": "P22059-1", "name": "Oxysterol-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------MAATELRGVVGPGPAAIAALGGGGAGPPVVGGGGGRGDAGPGSGAASGTVVAAAAGGPGPGAG-----GVAAAGPAPAP---------------------------------------------------------------------------------PTGGSGGSGA---------GGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDS----CNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLA-------------------ESDESG--DEESVSQTDK------TELQNTLRTLS------------------------------------------------SKVEDLSTCNDLIAK-----------------HGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANTPG------------------------------------------------------------------------------------------NVGSGKDQCCSGKGDMSDEDDENEFFDA-------------------PEIITMPEN-LGHKRTG-----------------------------------------------SNISGASSDI---------------------------SLDEQYKHQLEETK--------------------------------KEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAE-SKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHH----YTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGD--KCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVI--GENGGDARQR--------------------------GHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWES----GTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKAT----EDG---------------------------------------------------------------TPY---------DPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWSSCPDIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TLT7-1", "uniprot_id": "A0AB32TLT7_DANRE", "id": "A0AB32TLT7-1", "name": "Oxysterol-binding protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEPKAPT---------------------------------------------------------------------------------PAPG-------------------DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDS----CNFVISNGGTQTYHLKASSEVERQRWITALELAKAKAFRMQA-------------------ESDDSG--DESTPPAAGQGGGARNSEVQSTLRTLG------------------------------------------------SKVEDLSTCNDLIAK-----------------HGSALQRSLSELEGVRLGGETSEKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAEREQRVRLEETLEQLAKQHNHLERAFRGATVLPPSQSN------------------------------------------------------------------------------------------PAIDSKG-SVPGKGDASDEDEENEFFDACED---------------VQEFITVPADPKYHRRSG-----------------------------------------------SNVSGISSEMGMDD--------------------GTTSLDEQSMASNPESPQSQEVVPV------------------------RKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLSEDLEYYELLDRGAKCQSSLEQMCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHAI-SERGWTLRQEIALASKFRGKYLSIMPLGSIHCIFEKSNNH----YTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHRTGD--RCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGADGRQK--------------------------TVYQTLKAKELWRKTPLPEGAENMYYFSTLALTLNEPEE----GVAPTDSRKRPDQRLMEQGRWEEANAEKQRLEEKQRTARREREREANRSAN--PEEGKEPADGALIEDSISDSPLKTEEVEIATEPSETTDKTDTDETSSDLSLSTETLHGSHPPSYSMEGPYGAPVKSGHQDSYKAMWFDRCVDPMTGEPTHIYRGGYWETKEQGNWDSCPDIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC05-1", "uniprot_id": "Q9VC05_DROME", "id": "Q9VC05-1", "name": "Oxysterol-binding protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDAAGNALA----------------------------------------------------------------------------------EKGLP------------------EMKGWLLKWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGALIHTVDS----CTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIEC------------------EEEEET---ETAHVVPSQ-------EISSVVRDLT------------------------------------------------DRLESMRTCYDLITK-----------------HGAALQRALNDLETNEEES-LGSRTKIVNERATLFRITSNAMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVRQ-------------------------------------------------------------------------------------------------NKPVSSTSGAGTAGSLVTSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQ---------------------------------------------VEGHLEGSSSESDEQKRTVQTVQQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLI-----------------KKRRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCE-SKN-WTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRR----YSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTS-------GSVSS--------------------------PTYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEE----GVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAA----AEGRP------------------------------------------------------------------------YPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12451-1", "uniprot_id": "OSH2_YEAST", "id": "Q12451-1", "name": "Oxysterol-binding protein homolog 2", "aln": "MSREDLSIAEDLNQVSKPLLKVKLLEVLGQGDFKHLKALVDNEFQPKDDPSVQQVLNLILHYAVQVAPILLIKEIVAHWVDQVGDEKSSSKSDDGIHLDLNYQDENGNTPLHLAAAQSRSDVISFLLSQKSINDCVKNKAHQQPLDMCKDLNVAQMIQLKRDDYFLETVHSLRAAMNKRDFSKLDSIWKNPRNLNLLDINGIDPETGTTLLYEYSQKKDIEMCQWLLKHGAEATVKDGKGRSPLDLVKNIKLPAKPSNNVTPEIKLKNLLEKNLREQAIVHEDVASSKPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDRPRGTLKVSTCRLHIDSSEKLNFELLGGITGTTRWRLKGNHPIETTRWVNAIQSAIRFAKDKEILNKKKAVPPSLALKNKSPALISHSKTQGSLPEASQYYQHTLHKEVIQPSSVSLYRRPSNNLSVVSSEIQLNDNLTESGKRFVSKMIENRLDGSKTPVGVHTGSALQRVRSSNTLKSNRSMQSGSGVASPIDKVPNGANLSQSNTTTGSTASLSDNNYIDNFEGDEANSDDEEEDLGINFDRDEEYIKAQYGPYKEKLDMYEQAISIELSSLIELIEQEEPSPEVWLTIKKSLINTSTIFGKLKDLTYKRDKRLVDMVSKQGDVNNVWVQSVKELEMELSNKTERLASIDKERRGLKKILHKKLLESHATAGNKESLENDKEQESDTTASTLGQIAKFISATKEEDEASDADEFYDAAELVDEVTELTEAHPEISTAAAPKHAPPPVPNETDNDSQYVQ----------------------------------DEKSKIESNVEKTSQKFEKQNNLVTEDEPKTDQSLKNFKAEDKESQVKEKTKEIASSVIGEKTIVAVTTVQKRKEEYLLKEGSYLGYEDGIRKRLSMDKDDRPKISLWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAKPFNPLLGETFEYSRP-DKQYRFFTEQVSHHPPISATWTE--SPRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGD--HCKLYFKARGWRS-SGAYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKTRTAASAG-----------------------NGPTDDGTKFLIWKANDRPEEP---FNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREEN--------------------------------------------------------------------------------------NLEYHPQWFVRDTHPITKAKYWRYTGKYWVKRRDHDLKDCGDIF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::** . . :.:* :::. :* :::::.:*: **** *:***: * *: ::. . . : :***:.*: :: * .*****:****:* * : * : **:***** :* : . ** *: .. * : . * * : * .:::*: ::: * : : . : . * * * . . . . : * : : . . : * * : *: * . : :: :: ** : . ** * *** * ** * : :. ** *:**:** *:.* : . ** . : : . *: . *:", "identical_positions": 83, "similar_positions": 99, "identity": "5.78%" }, { "cls_id": "homologset.agr.SGD:S000002179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16290-1", "uniprot_id": "PGAM2_RAT", "id": "P16290-1", "name": "Phosphoglycerate mutase 2", "aln": "------MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEF-----DICYTSVLKRAIRTLWTILDVT--------------------------DQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRY--AGLKPEE---------------LPTCESLKDTIARALPFWNEEIAPKIKAGK--RVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70250-1", "uniprot_id": "PGAM2_MOUSE", "id": "O70250-1", "name": "Phosphoglycerate mutase 2", "aln": "------MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEF-----DICYTSVLKRAIRTLWTILDVT--------------------------DQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRY--AGLKPEE---------------LPTCESLKDTIARALPFWNEEIAPKIKAGQ--RVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15259-1", "uniprot_id": "PGAM2_HUMAN", "id": "P15259-1", "name": "Phosphoglycerate mutase 2", "aln": "------MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEF-----DICYTSVLKRAIRTLWAILDGT--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRY--AGLKPGE---------------LPTCESLKDTIARALPFWNEEIVPQIKAGK--RVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBJ1-1", "uniprot_id": "PGAM1_MOUSE", "id": "Q9DBJ1-1", "name": "Phosphoglycerate mutase 1", "aln": "------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEF-----DICFTSVQKRAIRTLWTVLDAI--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRY--ADLTEDQ---------------LPSCESLKDTIARALPFWNEEIVPQIKEGK--RVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25113-1", "uniprot_id": "PGAM1_RAT", "id": "P25113-1", "name": "Phosphoglycerate mutase 1", "aln": "------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEF-----DICFTSVQKRAIRTLWTVLDAI--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRY--ADLTEDQ---------------LPSCESLKDTIARALPFWNEEIVPQIKEGK--RVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18669-1", "uniprot_id": "PGAM1_HUMAN", "id": "P18669-1", "name": "Phosphoglycerate mutase 1", "aln": "------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEF-----DICFTSVQKRAIRTLWTVLDAI--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRY--ADLTEDQ---------------LPSCESLKDTIARALPFWNEEIVPQIKEGK--RVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N0Y7-1", "uniprot_id": "PGAM4_HUMAN", "id": "Q8N0Y7-1", "name": "Probable phosphoglycerate mutase 4", "aln": "------MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEF-----DICLTSVQKRVIRTLWTVLDAI--------------------------DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRY--ADLTEDQ---------------LPSYESPKDTIARALPFWNEEIVPQIKEGK--RVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVCKAIEAVAAQGKAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15327-1", "uniprot_id": "PMGE_MOUSE", "id": "P15327-1", "name": "Bisphosphoglycerate mutase", "aln": "------MSKHKLIILRHGEGQWNKENRFCSWVDQKLNNDGLEEARNCGRQLKALNFEF-----DLVFTSILNRSIHTAWLILEEL--------------------------GQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPYFHEIYSDRRYKVCDVPLDQ---------------LPRSESLKDVLERLLPYWKERIAPEILKGK--SILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGNQEAIQAAIKKVDDQGKVKQGKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07738-1", "uniprot_id": "PMGE_HUMAN", "id": "P07738-1", "name": "Bisphosphoglycerate mutase", "aln": "------MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEF-----DLVFTSVLNRSIHTAWLILEEL--------------------------GQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQ---------------LPRSESLKDVLERLLPYWNERIAPEVLRGK--TILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12008-1", "uniprot_id": "PMG2_YEAST", "id": "Q12008-1", "name": "Phosphoglycerate mutase 2", "aln": "MTASTPSNVMTLFLLRHGQSELNHENIFCGWIDAKLTEKGKEQARHSAELIEQYCKANNLRLPQIGYTSRLIRTQQTIETMCEEFKLKPQLQVVYDFNKIKLGDEFGSDDKDNMKIPILQTWRLNERHYGSWQGQRKPNVLKEYGKDKYMFIRRDYEGKPPPVDLDREMIQQENEKGSSTGYEFKEPNRQIKYELECSNHDIVLPDSESLREVVYRLNPFLQNVILKLANQYDESSCLIVGHGSSVRSLLKILEGISDDDIKNVDIPNGIPLVVELDKNNGLKFIRKFYLDPESAKINAEKVRNEGFIKNP--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.::***:. * ** *. * * .*. * *:*:. . :. :: ** * :* : : .: :*: :*********. * .: : ::*: : : **.:: ***:: .: . .. . : ** ** ::.: * *: :: * . ** .**.* :.: * :**:*:: * :: :*.*:*:: **::: :* : *: : * :* * ", "identical_positions": 62, "similar_positions": 77, "identity": "19.81%" }, { "cls_id": "homologset.agr.SGD:S000002180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35077-1", "uniprot_id": "GPDA_RAT", "id": "O35077-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "---------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNAS-QLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNG-LKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGS-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFICCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13707-1", "uniprot_id": "GPDA_MOUSE", "id": "P13707-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "---------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNAG-RLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAIPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKDLMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGT-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFIRCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21695-1", "uniprot_id": "GPDA_HUMAN", "id": "P21695-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "---------------------------------------------------MASKKVCIVGSGNWGSAIAKIVGGNAA-QLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGP-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ULJ0-1", "uniprot_id": "GPD1L_MOUSE", "id": "Q3ULJ0-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "-------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVK-TLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHKICDEITGRVPEKALGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVMQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAP9-1", "uniprot_id": "D3ZAP9_RAT", "id": "D3ZAP9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVK-NLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLGEAVQDADLLVFVIPHQFIHKICDEITGRVPKKAVGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVLQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLCCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRKVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N335-1", "uniprot_id": "GPD1L_HUMAN", "id": "Q8N335-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "-------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGNNVK-KLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG-LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZKP8-1", "uniprot_id": "A0A8I5ZKP8_RAT", "id": "A0A8I5ZKP8-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-------------------------------------------------MGATTLRVCIVGFWSWGSAIAKIIGTNVK-NQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRG-LMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNG---------ILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQ-VSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ALX9-1", "uniprot_id": "A0A8I6ALX9_RAT", "id": "A0A8I6ALX9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "MTHYTRVVNVFFKQVGRQAGQGTSRLDQIDGGQQLAEKAPSPQQDIGLKVLPGPLKVSIVGSGNWASAVSKIIGNNVK-TTKKFASPVKMWVFEEIVNGRKLTDIINTDHENVKYLPGYRLPENVIATPSLSQAVQDADLLVFAFPHQFIRKICDELAEVVPRKARGLTLIKGIDEGPES-LKLISDIIREKVNIDVSVLMGANLANEVAAEQFCETTIGSKVLQNG---------LLFKELFQTPNFRVTVVEDPDTVELCGALKNIVAMGSGFCDSFCCGNSTKAAVIRLGLMEMISFVRTFSKGQ-VSIATFLESCGVADLISTCYGGRNRKVAEAFARTGKSLEELEKEMLKGQKLQGPHTSAQVYRILKQKGLLDKFPLFTVVYQICYEGRAVTELIPCLQNHPEHRRRELGTSPALPHPSQGHTDTRT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XIZ6-1", "uniprot_id": "GPD1L_DANRE", "id": "Q5XIZ6-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "--------------------------------------------------MAAPLKVCIVGSGNWGSAIARIIGSNAQ-KLQCFATTVKMWVYEEMVNGKKLSEIINTEHENVKYLPGYKLPENVVAVPQLRDAADGADLLVFVVPHQFIRKLCDEMMGCVSERARGITLIKGIDEGPEG-LKLISDIIREKMGIDVSVLMGANIANEVAAEKFCESTIGSKVLENG---------LLFKDLLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLQCGDNTKAAVIRLGLMEMIAFAKLFSKDDSVSSATFLESCGVADLITTCYGGRNRRVAEAFAKTGKSIEELEKEMLNGQKLQGPLTSAEVYHILKQKGLVEKFPLFTAVYQICFEDKPVRDMITCLQSHPEHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13706-3", "uniprot_id": "GPDA_DROME", "id": "P13706-3", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------MADKVNVCIVGSGNWGSAIAKIVGANAA-ALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYLKGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYG---------KVLRDLFQANHFRVVVVDDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGS--KLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFTAIHKICTNQLKPNDLIDCIRNHPEHMDTSIMPSPKL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00055-1", "uniprot_id": "GPD1_YEAST", "id": "Q00055-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 1", "aln": "------------------MSAAADRLNLTSGHLNAGRK--RSSSSVSLKAAEKPFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKG-VQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEIIRFGQMFFPES-REETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1U3-1", "uniprot_id": "Q9W1U3_DROME", "id": "Q9W1U3-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "---------------------------------------------------MDKIMICIIGSGNWATTIARNVGRNVL-NSQTLDEKVPMYVYEEIVEGRKLTEIINTTHINSKYMPNFELPPNIVAVDDIVTTARDADIIIFAIPPTFVSSCCKTLLGKVKPTAHAVSLIKGFERGDDGQFVLISQIIMRQLKIPCSVLVGCNLAHELAHDHFAEGTVGCRDQKYY---------RVLHDIFKSPTFRVVVTEDADCVEICSTLRNIIAFAAGCSDGMELNENTKGGIIRRGFLEMLQFVDVFYPGC--RMGTFFESCGISDLVTSCYANRNRKLAEAFVKTGKPLSELEHILIPGHEPLGPVTAELVHHMLKKKGLEDKFPLFTTVYRICTGDYPLQRLVETLIKAREDIFHPLHTFQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IN06-1", "uniprot_id": "Q8IN06_DROME", "id": "Q8IN06-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "--------------------------------------------------MAGKLKICIIGAEGWGSAIAAVVSNNVL--EGDFDSRVHLYVYDEMIRDTALSEIINTRHENVKYLPGIKLPNNLIAVNDLLEAAQNADILVFSTPLEFVQSYCNILSGNVKESAFAVSMTKGLLSENGEGIELVSHAISESLGIPCYSMMSAHSAMEMAQGKLCEVTIGCSDNSHS---------KLLISAMQTNNCRVISVNDVDGVELCGTLTDVVALGAGFIDGLRLGENARLAAIHLGVKEIMRFIKTFFPSS--KMSTFYESCGVTNAVASSFVDKNVTFAKSLVTSGQTIEEIEANLHSGRKLLGPMVASNVNAFLENGLMQHEFPLFTAIHLICQSEAPPELMIEALRNHPDLSSSSISHLLNHERDELKTDQGLPELRTALDKILTEAGNENIKQLKVMDDWTEVNDYDVEETYHEKVASRDSCLETEIMPSRLSVQAAQLYNDIRDGNVGVAFKMDIDEGNRQVRLLLEKEDEMASDAALTVISSRLTAGQEDDNARIGHGHITNTSAESDHMSSKSIPSGLTTKDSPDVLDLSCESEPLHSSKQNSQLMEDAETNFTERLKVNQLKEQIDKQEAANFKAQENLIKSIRQTIQALGDKEKMENLIAKSKMEEDPFQLKSQVESSQLKSQVEGESSELKNQIQEEAYEPISQADEEPSQIRSQLDEESAQLKSLMDEENRQLESEMQDESSLLKSSADKSEFVAYNAEEEQPIEEPTDNHQYKLRSDTNKLKELMFTDSREHLESEKHIEVKLQDEHDFDLDEEPAIGKKDPTYTKENLELQERLEWQKLKQTDKPHHPYSSADLEDSTTNEGNARLPIEHDNRFQNVDRYQDRELVQVRAELKETSGAESEKEINLISEQRPDQNQDEVNLRPHSHIKTEETGHHEWDWLMNNEKIDSDEQKFYANERMETLSESDQDKLQNLNYQLKEALQHDLDVMSASRGNDSNEVLSEEDSNPEAAKKITEQPLNPTPNQIPAVPLPVTMPSKQSHIREGSPQFQNQPRSVPPPSPQTKPQSPKEQQPRRTNAPVEFGNKDEAMDLNESASDQEVPKRKKISKTEAVIEPVAKDVSMAEPNESLHSKKETSPASLSKQESKRKQKRSLRRPSSDSDSTKTTNEFEKQRQIIENQKAQLEKMGKKISVMRQGQDRRVSYKGHNPYSADPDLESRPPMDTSFEKDRTGDYQGLGHQRRKVVVAPPFHPPINPRVRVPRPPFDGRDHEFHTMTTAPVDRHLAPAAKWSSLPTTLKLNRNSLVANIQVKHFAALPCQALPKPILKLPMGVPRTPTFSKILCALQLGLLASYLACRKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .*.:::: :. * : * ::* :* : . *::*** * * **: . ** *::* .: :. ..*:::* * *: *. : : . .: :.. . *:* * . : : : ..: * *:* . .* *:. :: :: : :: :.:*.:* .::* . . :.: .:.: . : *. *:: * * : **.*.:: :: . . : :. : *: : : : *: * .. : *. .**** .:: : : : . ", "identical_positions": 49, "similar_positions": 115, "identity": "3.58%" }, { "cls_id": "homologset.agr.SGD:S000002182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2L6-1", "uniprot_id": "MINP1_MOUSE", "id": "Q9Z2L6-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "MLRGARSHLPASVAPAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDANPWLLVDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLKQLQGLLQTRE-------SRDGGSQ------VAAALAEWPLWYGDWMDGQLVEKGRQDMRQLALRLAALFPDLFSRE-NYDRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECGPPRINDKLMRFFDHCEKFLTDVERNETALYHVEAFKTGPEMQKVLKKVAATLQVPMNSLNADLIQVAFFTCSFDLAIKG----------VHSPWCDVFDVDDARVLEYLNDLKQYWKRSYGYTINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVNRKFRSGHIVPYASNLIFVLYHCDNAQSPEEQFQIQLLLNEKVLPLAHS---QRPVGLYEELKTHYRDILQSCQTSKECSPPKANITSDEL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35217-1", "uniprot_id": "MINP1_RAT", "id": "O35217-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRE-------SVDGGSR------VAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRE-NYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAIQG----------VHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSSVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHS---QKTVALYEDLKNHYQDILQSCQTSKECNLPKVNITSDEL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNW1-1", "uniprot_id": "MINP1_HUMAN", "id": "Q9UNW1-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "MLRAPGCLLRTSVAPAAALAAALLSSLARCSLLEPRDPVASSLSPYFGTKTRYEDVNPVLLSGPEAPWRDPELLEGTCTPVQLVALIRHGTRYPTVKQIRKLRQLHGLLQARG-------SRDGGASSTGSRDLGAALADWPLWYADWMDGQLVEKGRQDMRQLALRLASLFPALFSRE-NYGRLRLITSSKHRCMDSSAAFLQGLWQHYHPGLPPPDVADMEFGPPTVNDKLMRFFDHCEKFLTEVEKNATALYHVEAFKTGPEMQNILKKVAATLQVPVNDLNADLIQVAFFTCSFDLAIKG----------VKSPWCDVFDIDDAKVLEYLNDLKQYWKRGYGYTINSRSSCTLFQDIFQHLDKAVEQKQRSQPISSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNYKKQMHRKFRSGLIVPYASNLIFVLYHCENAKTPKEQFRVQMLLNEKVLPLAYS---QETVSFYEDLKNHYKDILQSCQTSEECELARANSTSDEL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W438-1", "uniprot_id": "Q9W438_DROME", "id": "Q9W438-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "MLSQFYCLF---LLLLHFFVGVTLSEEGECRRLNRAD-----IEGRLSTKTPYRAIANYDETPPKYAG---------CHPTRIWTIIRHGTRNPSESVILQAQNRLSEIKKRI-------LDQTKPPICTAELEKLRQWHWMHLNATEDEKLLVAEGEDELIELAERMQRRFPDLLPELYNPEWYYFKYTATQRTLKSAESFATGLFGRHR-------IHTVRYPPPLHEDPVLRFYKGCGKWKTDVDKNPETLVNARRFLAEPQMQSAVEQVRSSTRLP--DLQPEDVQLMYTVCAFETAWHRPRHDSGSKSSYESVWCNFFDVAALEALEFFEDLEYYWNDGYGYELTHRIACPAIADMFAAISSSEETRQRR----ANATLYFTHSGTLLKLLAHLGLARDNKPLTHKHFAS--ERLWRTSQIDAFATNLAFLRYDCDKGNP-----QVLVLHQERVVRLPGCPQ-DKDLCPLATLRRIYANSVDHCDREKMCRV---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VV72-1", "uniprot_id": "MINP1_DROME", "id": "Q9VV72-1", "name": "Multiple inositol polyphosphate phosphatase 1", "aln": "----------MRLLILLLLPLVAIAQDDYCFSKDTSR----LQTRQFSSKTAYQIVKGTDIDKQYLVPG--------CQPQKMWIFHRHGTRLPKKSMINKASRVAELRDLIINNYQVARTKPETDALCQTDLIAIKLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYPTVLTANYNDTYYQFRHTDTQRTTESFKAFAEGLFGSQN------AAHPVEIP---KQDLLLRPYDYCSSFKNVNYKDEGSEY--YKFHQSKLYNDTLADISTRLGFLY-TLEEADIKLMYDMCRYEQAWNVD---------RNSVWCGAFLPEQITVFEYLEDLKYYYGSGYGFPENAHLNCRLVQDLLTHLSNPVS---------PHVVAHFGHSTGLLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDCPADLDRE---KVVFFLNQQAVQLDWC---SVGLCKWSDVLEKYKTIADADCGEYYCRTGGAPSLGSGVGGLLATTLAAMLVYLMH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52290-1", "uniprot_id": "PPAD_YEAST", "id": "P52290-1", "name": "Probable acid phosphatase DIA3", "aln": "MVKPVIFAICLGVLLSKALS-IPLRSFADIELIGSQK----SLFPFLGGSAPYFSFPANYGIPTDIPEG--------CRLTQVQMIGRHGERYPTRSEAKDIFEVWYKISNYTGKYEG--SLSFLNNGYEFFIPDESLLEMETTLQNSIDVLNPYTGEMNAKRHAREFLAKYGKLMENC---TNFPIFTTNSKRIYDTAQYFAEALGDGFN------ISLQTLSENSSSGANTLAAKSSCPNWNSNANNDILMSYSRDYLEN---ISDRLNDENKGLNLS-----RKDAAALFSWCAFELNAKG-----------YSNICDIFSAAELIHYSYETDLTSFYQNGPGYKLIKSIGANLFNATVKLIRQSAHLD-------QKVWLSFTHDTDILNYLTTAGLIDDTRNLTTN-HVPFRDHSYHRSWYIPQGARVYTEKFQCSNDSY------VRYVVNDAVVPIESCSSGPGFSCEEGTFYEYAKDRLRGVSFYEDCDVSKVSKEKELTFYWDWNTTRYNASLVNQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :. .: * * :: : *** * *. . . . . . : * : * : :: : : .:* .: * .* . : . * .: . .: : . : . . : * :: : * *. * .: ** :: . *: . . . : .. . * * :* *: * * * . : :: . . .:.. :.* : . :: .: : . . * ", "identical_positions": 29, "similar_positions": 83, "identity": "5.52%" }, { "cls_id": "homologset.agr.SGD:S000002186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2S5-1", "uniprot_id": "A0A0G2K2S5_RAT", "id": "A0A0G2K2S5-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGRNLTIDSIMNKVRDIKNKIN-EDLTDELNSIKVCVDPT---ETVNQIMMVENTPENWLNFLLKLEKNSPPLND-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRLAELKAIQEPDDAH-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAIRNLHLQKKQLLSEEDKKSLSAS---------------------TVLTAQESFSSSLGN-------LQSRKSSCDPKV------------------QAAAARILYGENMPPKDAEVSHRNPLKQTNKTKRSCPFGRVPVNLLN---SPDYY------VKTDGSAVPQFTKRKISGSE------------------------------YRDSIMPG---------------SKSSGNDSY--------ELRGLKP------------------------------------IQAIHLKDSLVSNEKSSELMS-DLVTLKSKTDSS-LTKLEVSEPKVRQEPEIPERRHKQWQSARKPGCGIQ-NSAAFAPQWHVPDVTPK-ADKEQKCTTVEQLAFSVSKQSPPLSVPKWIDPKSVCETPSSSSLDDYMKCFKTSVVKN-EFPPACPSSTPYSQLARHQQHQQQGLSTPLQNLQISGSSSMSECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DRYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENGKIKTKISPRSDVWSLGCILYYMTYGKTPFQHIINQVSKLHAIIDPSHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLAHPYVQIQPHPGSQMAKETTDEMKYMLGQLVCLNSPNSILKAAKTLYERYNCGESQAPSSSKTSDKKRERE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35761-1", "uniprot_id": "TTK_MOUSE", "id": "P35761-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGSSVTIDSIMSKMRDIKNKIN-EDCTDELSLSKICADHT---ETVNQIMRVGNTPENWLNFLLKLEKNSSPLND-DLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDAR-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSAS---------------------TVLSAQEPFSSSLGN-------VQNRSISCESRG------------------QAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLN---SPDFY------VKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLA-----LAGLAKGSGPDRDAILPG---------------SRPRGSDSY--------ELRGLKP------------------------------------IQTIYLKDSLVSNEKSSELMS-DLIALKSKTDSS-LTKLEETKP------EIAERRPMQWQSTRKPECVFQ-NPAAFAPLRHVPDVTPK-ADKE----------------SPPISVPKWLDPKSACETPSSSSLDDYMKCFKTPVVKN-DFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEIT--EQYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAIINPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATDEMKYVLGQLVGLNSPNSILKTAKTLYERYNCGEGQDSSSSKTFDKKRERK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33981-1", "uniprot_id": "TTK_HUMAN", "id": "P33981-1", "name": "Dual specificity protein kinase TTK", "aln": "MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSD-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDAR-DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSAS---------------------TVLTAQESFSGSLGH-------LQNRNNSCDSRG------------------QTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLN---SPDCD------VKTDDSVVPCFMKRQTSRSE------------------------------CRDLVVPG---------------SKPSGNDSC--------ELRNLKS------------------------------------VQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQ--EPEVPESNQKQWQSKRKSECINQ-NPAASSNHWQIPELARK-VNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKN-DFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DQYIYMVMECGNIDLNSWLKKKKS--IDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSS----RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AYG3-1", "uniprot_id": "TTK_DANRE", "id": "Q8AYG3-1", "name": "Dual specificity protein kinase Ttk", "aln": "MDEEESTERQMQIAMLCQKLAMMKQLFN-EDDTDYIN-----------------QAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQ-TSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAEN--VEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNP--NSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEIT--SSYIYMLMECGHLDLNTWLRNRKT--VKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSS-------NGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG66-1", "uniprot_id": "A0A0B4KG66_DROME", "id": "A0A0B4KG66-1", "name": "", "aln": "----------MTTPVPRRTKDMMALGLD------------------------------SDSEDDFNTPYRPRQAAAGERKQQPVASFQVQTRGKENEPHPLP-------INMLPRRVSELTMMDSDSDEE-DIKSNHNLNCAILNDSFVLSPSQELTNSNSN-----ITTRRTPSAAPLKQSDSNLSFLGRFNDMGINCSSQGSPVAN-------------------------SEKQVAKKTAP--------------------------------------TLQAAPSATERRPLQETETPLRNELPSTSKTKPDADFITPQVRTIG-------------------------------------------------------------------STLAG-------------------------------------------------------------------------------KSRSAVSNDFRAQKVLFQTPMTVSRAAPVA-----------------------------------------SDSISFSLCDTITE---------------------SPDIPEPPKKAEPPKSQHPSKKSLDH---VFRESDKDN------VPDKVDNVEPKELVSIPAVAVPPEQPSHKTSN------ILKIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGN-VCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTN-LPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPP-----YYPIMLVHFTTVSALFADGQELPTVESQKAAVVHRTTTVPIPYDHSAAEPADTQQNRQQQLSTKAQLFISEMSKVKCLSHMCVYIFNSHFIVN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54199-1", "uniprot_id": "MPS1_YEAST", "id": "P54199-1", "name": "Serine/threonine-protein kinase MPS1", "aln": "------MSTNSFHDYVDLKSRTNTRQFS------------------------------DDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAER---RSKRFLISNRTTKLGPAKR---------------------AMTLTNIFDEDVPN---------------------------------------SPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLP-------TSDLPLISQIYFDKQREEN-------------------------------RQAALRKHS------------------------------------------------------------------------SRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSS--------SSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISR-------------------NKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQ-KRVIQLLDYEMG--DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQN-RLLAIMNPDVKIPFPEHTSNN---------EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . : . ..:*. . . . : : .. *: .* . . : : .. : . . :. : . :. . . .. . ::: :. : : . : : . . . : :.::. : : :* **** *: . . * * . ::.: .* * :*: :: * **:: . :*::** *. **. *.. . : :** .:: :*. *::*********::*.* **:******. : . ..: : :* ** **:.***: . *:. .*:** ***:* : * :.*: : . :: ** * .* :* . : . : . : : : : . . . : ", "identical_positions": 70, "similar_positions": 140, "identity": "6.88%" }, { "cls_id": "homologset.agr.SGD:S000002187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61161-1", "uniprot_id": "ARP2_MOUSE", "id": "P61161-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61160-1", "uniprot_id": "ARP2_HUMAN", "id": "P61160-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M7U6-1", "uniprot_id": "ARP2_RAT", "id": "Q5M7U6-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SXW6-1", "uniprot_id": "ARP2A_DANRE", "id": "Q7SXW6-1", "name": "Actin-related protein 2-A", "aln": "MDSQGKKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDSRNCKILLTEPPMNPTKNREKIIEVMFETYQFSGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFGAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTREEYQEKGTRVLEKLGVTVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q56A35-1", "uniprot_id": "ARP2B_DANRE", "id": "Q56A35-1", "name": "Actin-related protein 2-B", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNINSRDCKILLTEPPMNPTKNREKIIEVMFETYQFTGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKENLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWLTREEYQEKGVRVLEKLGVTVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45888-1", "uniprot_id": "ARP2_DROME", "id": "P45888-1", "name": "Actin-related protein 2", "aln": "MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIG-DIEVKDLHVDDLMVGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKLQKISH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32381-1", "uniprot_id": "ARP2_YEAST", "id": "P32381-1", "name": "Actin-related protein 2", "aln": "MDP--HNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLK-----DIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. :: :* *:****** * **.*** : **::****::*: : . :* *:*:*****::** *::.******:::** ** :***:* : .. . *********** *****: *****.* * ..*:******:****** :***:********* **** . *.*******:****:**:**.** ******::******* :**:***:.*::: : :** ***.***** ***** **** *** ***.**** *::** *:.** ***:*:**:* *..:** *******:**********:*:***::.***:.* .:* ***:*********.***:******.: *:* :*::::*:**.* .: *: ", "identical_positions": 237, "similar_positions": 94, "identity": "59.25%" }, { "cls_id": "homologset.agr.SGD:S000002188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D554-1", "uniprot_id": "SF3A3_MOUSE", "id": "Q9D554-1", "name": "Splicing factor 3A subunit 3", "aln": "METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKER-KNAEYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQTDFEKKWDNGTFPGWP-KETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSLFAKNPKSK---GTKRDTERNKDIAFLEAQIYEYVEILGEQRQLTHENVQRKQARTGEE--------------------REE-EEEEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASE--------------RWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12874-1", "uniprot_id": "SF3A3_HUMAN", "id": "Q12874-1", "name": "Splicing factor 3A subunit 3", "aln": "METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKER-KNAEYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWP-KETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSLFAKNPKSK---GTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEE--------------------REE-EEEEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASE--------------RWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46106-1", "uniprot_id": "NOI_DROME", "id": "O46106-1", "name": "Splicing factor 3A subunit 3", "aln": "METLLEQQRRLHEERERLVKLMVDEHATKKPGEKERIHSEHRLKYLMELHHNSTSQLRDLYEDKDNERKAEIAALSGPNEFNEFYARLKQIKQFYKSHPAEVSVPLSVEFDEMIRVYNNP-DDMSALVEFTDEEGGGRYLDLNECYELYLNLRSVEKLDYITYLMSFDHVFDIPRER-KNREYRIYIETLNDYLHHFILRIQPLLDLEGELLKVELDFQRQWLMGTFPGFSIKETESALANTGAHLDLSAFSSWEELASLGLDRLKSALVALGLKCGGTLEERAQRLFSTKGKS--TLDPALMAKKPSAKTASAQSREHERHKEIAQLEALLYKYADLLSEQRAATKENVQRKQARTGGE--------------------RDDSDVEASESDNEDDPDADDVPYNPKNLPLGWDGKPIPYWLYKLHGLNISYNCEICGNFTYKGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAITLWEKLKSQKQSE--------------RWVADQEEEFEDSLGNVVNRKTFEDLKRQGLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19736-1", "uniprot_id": "PRP9_YEAST", "id": "P19736-1", "name": "Pre-mRNA-splicing factor PRP9", "aln": "-MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFPDTKLPRSSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINRPEETQEDDKDLPNFERKLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDLDLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLD-----DEKYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDFEHSY-CRGSLRSEAKGIYCPFCSR-WFKTSSVFESHLVGK---IHKKNESKRRNFVYSEYKLHRYLKYLNDEFSRTRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDGEQRDGQLQEEHLSGKSFDMPLGPDGLPMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHLRCLGIEPSSVFKGITKIKEAQELWKNMQGQSQLTSIAAVPPKPNPSQLKVPTELELEEEDEEGNVMSKKVYDELKKQGLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:** :* ** * : . :... : . *:.. : . . ..:*. *. ** : :. : : :: : * : : * . :: :: : :: .: . * : : .: . : : *. : ::.:* .: : * . : . : :: : : * : . :.:: . . .. : * : . ::: *.*: * : .::.* .: . . * *:*...*: ::.. . .::: .: .* .:: .:.:::. * ::.* . *.:: *:. *:** * *. * ..: : . .: :.: : :.: :. ::*** ** *:**********: .*.****.* .*.* ::*:*** * ** : :***** :: * .:*:*::* ** ::: *. : .: * * **. ***:.:*.:::**:***:", "identical_positions": 94, "similar_positions": 186, "identity": "17.38%" }, { "cls_id": "homologset.agr.SGD:S000002189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4L0-1", "uniprot_id": "DDX54_MOUSE", "id": "Q8K4L0-1", "name": "ATP-dependent RNA helicase DDX54", "aln": "MAAGRRVGPGPPSRPTMAPWKKKR-LRKRRTGASQGRDSDSDDGEFEIQAEDDAR---------------------------ARKLGPGRALPSFPTSECVS------------DVEPDTREMVRAQ--NKKKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKARSAQTGARALILSPTRELALQTMKFTKELGKFTGLKTALILGGDKMEDQFAALHENPDIIIATPGRLVHVAVEMNLKLQSVEYVVFDEADRLFEMGFAEQLQEIIGRLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDSKLNEQLKTSFLLVREDTKAAVLLYLLQNVVRP-----------------------------------------------------QDQTVVFVATKHHAEYLTELLMGQGVSCAHIYSALDQTARKINLAKFTHNKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEVPYLLDLHLFLGRSVTLARPCEEPSVADAVGR----DG-----------------VLGRVPQSVVDDEDSSLQTAMGASLDLQGLHRVANNAQQQYVRSRPAPSPESIKRAKELDLAELGLHPLFSSCFEEGELQRLRLVDSIKNYRTRTTIFEINASSKDPSSQMMRAKRQRDRKAVASFQQR---RQERQEGPADPAPQRELPQE------EEEEMVETVEGVFTEVVGQKRPRPGPSQGAKRRRMETRQRDQEFYVP-YRPKDFDSERGLSVSGAGGAFEQQVAGAVLDLMGDEAQNMSRGQQQLKWDRKKKRFVGQSGQEDKKKIKTESGRFISSSYKRDLYQKWKQKQ-----KIDDRDSEEEG---PSNQRGPGPRRGGKRGRSQGTSQPRASSVPAGRMRSELKTKEQILKQRRQAQKQR-FLQRGGLKQLSARNRRRAQELRQGAFGRGAPSRKGKMRKRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDD1-1", "uniprot_id": "DDX54_HUMAN", "id": "Q8TDD1-1", "name": "ATP-dependent RNA helicase DDX54", "aln": "MAADKGPAAGPRSRAAMAQWRKKKGLRKRRGAASQARGSDSEDGEFEIQAEDDAR---------------------------ARKLGPGRPLPTFPTSECTS------------DVEPDTREMVRAQ--NKKKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVRP-----------------------------------------------------QDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLFLGRSLTLARPLKEP--SGVAGV----DG-----------------MLGRVPQSVVDEEDSGLQSTLEASLELRGLARVADNAQQQYVRSRPAPSPESIKRAKEMDLVGLGLHPLFSSRFEEEELQRLRLVDSIKNYRSRATIFEINASSRDLCSQVMRAKRQKDRKAIARFQQGQQGRQEQQEGPVGPAPSRPALQEKQPEKEEEEEAGESVEDIFSEVVGRKRQRSGPNRGAKRRREEARQRDQEFYIP-YRPKDFDSERGLSISGEGGAFEQQAAGAVLDLMGDEAQNLTRGRQQLKWDRKKKRFVGQSGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQ-----KIDDRDSDEEG---ASDRRGP-ERRGGKRDRGQGASRPHAPGTPAGRVRPELKTKQQILKQRRRAQKLH-FLQRGGLKQLSARNRRRVQELQQGAFGRGARSKKGKMRKRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12389-1", "uniprot_id": "DBP10_YEAST", "id": "Q12389-1", "name": "ATP-dependent RNA helicase DBP10", "aln": "MAGVQKRKRDLEDQDDNGSEEDDIAFDIANEIALNDSESDANDSDSEVEADYGPNDVQDVIEYSSDEEEGVNNKKKAENKDIKKKKNSKKEIAAFPMLEMSDDENNASGKTQTGDDEDDVNEYFSTNNLEKTKHKKGSFPSFGLSKIVLNNIKRKGFRQPTPIQRKTIPLILQSRDIVGMARTGSGKTAAFILPMVEKLKSHSGKIGARAVILSPSRELAMQTFNVFKDFARGTELRSVLLTGGDSLEEQFGMMMTNPDVIIATPGRFLHLKVEMNLDLKSVEYVVFDEADRLFEMGFQEQLNELLASLPTTRQTLLFSATLPNSLVDFVKAGLVNPVLVRLDAETKVSENLEMLFLSSKNADREANLLYILQEIIKIPLATSEQLQKLQNSNNEADSDSDDENDRQKKRRNFKKEKFRKQKMPAANELPSEKATILFVPTRHHVEYISQLLRDCGYLISYIYGTLDQHARKRQLYNFRAGLTSILVVTDVAARGVDIPMLANVINYTLPGSSKIFVHRVGRTARAGNKGWAYSIVAENELPYLLDLELFLGKKILLT-PMYDS-LVDVMKKRWIDEGKPEYQFQPPKLSYTKRLVLGSCPRLDVEGLGDLYKNLMSSNFDLQLAKKTAMKAEKLYYRTRTSASPESLKRSKEIISSGWDAQNAFFGKNEEK--EKLDFLAKLQNRRNKETVFEFTRNPDDEMAVFMKRRR----KQLAPIQRKATERRELLEKERMAGLSHSIEDEILKG-DDGETGYTVSEDALKEFEDADQLLEAQENENKKKKKPKSFKDPTFFLSHYAPAGDIQDKQLQITN---GFANDAAQAAYDLNSDDKVQVHKQTATVKWDKKRKKYVNTQGIDNKKYIIGESGQKIAASFRSGRFDDWSKARNLKPLKVGSRETSIPSNLLEDPSQGPAANGRTVRGKFK-HKQMKAPKMPDKHRDNYYSQKKKVEKALQSGISVKGYNNAPGLRSELKSTEQIRKDRIIAEKKRAKNARPSKKRKF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. : . .: . ... : . * : **::*.: *::*: ... :* .. : :.:** * . * * *..* . :: :*.*:*.*.* *:*** *::.* :**:: **********:**:.:*:*.**********.*:***.*:**::*.: ****:****:****:**::. *::.: * *::.*: *** :*:**. : ***:*******::*: ***.*.*:****************** ***:*::. ** :**:*******: **:*.:***.:***:***.::*:.*:*: *: :: : * **::*::::: :. *::**.*:**.**:::** ::**.:** *** :* :* . * *:***:****:***:* *****::*...*:*:*****.****..* ***:** :*:******.****:.: *: * :. .. :* :** *: *: .. :. : :.::*: :.* :*:: * *:*.:.****:**:**: . : * . ** ::* :: .::* *.: *:**:. .. * : .*: :* * :* :*: *:* * .. .: :* : * *. :.*. . .: . .. *::: :* *::. * * . .:: *.::. .* ::.* *. ** .*: :: : :***:*:*::*. .* ::** * ***: *::*:: . ::.*.: : *:..*::. . . :** . *.: : .: :*. * : . *::: * : . . : : : **:. ..: :: . *. :: .* ** ", "identical_positions": 306, "similar_positions": 313, "identity": "30.33%" }, { "cls_id": "homologset.agr.SGD:S000002191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC37-1", "uniprot_id": "MTU1_RAT", "id": "B1WC37-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "----------------------MSALRHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWD---SLDEQG-ICAADKDCEDAYKVCQILDIPFHQVSYVKEYWNDVFSDFLNEYEKGRTPNPDISCNKHIKFSCFHHYAVDNLGAD--AVATGHYARTSLEDEEVFEQKHTKRPDGLFRNRFEVRNPVKLLQAADSFKDQTFFLSQVSQDALRRTIFPLGELTKDFVKKIAAENRLHHVLQKKESMGICFIGKRNLEHFLLQVSVSDVSGGLLWAGAPVVMKPVFQYLQPRPGKFISIE----DNRVLGTHKGWFLYTLGQRAKISG------LSEPWYVVEKDGTKGDVLVAPRVDHPALYRDLLRTNRVHWIAE--EPPAALVRDKMMECHFR-FRHQMALVPCVLTLNQD-GTVWVTAVKAVRGLALGQFAVFYKGEECLGSGKILRLGPSAYTLQKGKNRTRVAPEVSSDSP----GLHPTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAT5-1", "uniprot_id": "MTU1_MOUSE", "id": "Q9DAT5-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "----------------------MSALRHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWD---SLDEQG-VCAADKDCEDAYKVCQILDIPFHQVSYVKEYWNDVFSDFLNEYEKGRTPNPDINCNKHIKFSCFYHYAVDNLGAD--AVATGHYARTSLEDEEVFEQKHTKKPDGLFRNRFEVRNPVKLLQAADSFKDQTFFLSQVSQDALRRTIFPLGELTKDFVKKIAAENSLHHVLQKRESMGICFIGKRNLEHFLL------------------------QYLQPRPGKFVSIE----DNTVLGTHKGWFLYTLGQRAKISG------LREPWYVVEKDGTKGDVLVAPRVDHPALYRDLLRTNRVHWIAE--EPPAALVRDKMMECHFR-FRHQMALVPCVLTLNQD-GTVWVTAVKAVRGLALGQFAVFYKGEECLGSGKILRLGPSAYTLQKGKNRTRVAPEASSDSP----GLHPTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75648-1", "uniprot_id": "MTU1_HUMAN", "id": "O75648-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "----------------------MQALRHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWD---SLDEHG-VCTADKDCEDAYRVCQILDIPFHQVSYVKEYWNDVFSDFLNEYEKGRTPNPDIVCNKHIKFSCFFHYAVDNLGAD--AIATGHYARTSLEDEEVFEQKHVKKPEGLFRNRFEVRNAVKLLQAADSFKDQTFFLSQVSQDALRRTIFPLGGLTKEFVKKIAAENRLHHVLQKKESMGMCFIGKRNFEHFLL------------------------QYLQPRPGHFISIE----DNKVLGTHKGWFLYTLGQRANIGG------LREPWYVVEKDSVKGDVFVAPRTDHPALYRDLLRTSRVHWIAE--EPPAALVRDKMMECHFR-FRHQMALVPCVLTLNQD-GTVWVTAVQAVRALATGQFAVFYKGDECLGSGKILRLGPSAYTLQKGQRRAGMATESPSDSPEDGPGLSPLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503J2-1", "uniprot_id": "MTU1_DANRE", "id": "Q503J2-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "----------------------MGVLRHVVCAMSGGVDSSVSALLLKRMGYHVTGVFMKNWD---SQEEKG-LCSSDRDCEDAYKVCKMLDIPFHEVSYVKEYWHEVFSNLLWEYERGRTPNPDIICNKHIKFKHFYQYAVNTLGAD--AMATGHYARTSQEDEEVFQQKLTEAPKSLFRDRFEIRKPVRLYQGADLLKDQTFFLSQISQDALRHTLFPLAGLTKGYVKKIAAEAGFQHVLKKKESMGICFIGKRDFENFIL------------------------EYLEPRPGNFVSIE----DGQIMGKHKGWFTLTLGQRARIGG------RADAWFVVDKDVTTADVFVCPSTFHPALFRDTLQTDRFHWIAE--EPPAELVHTQMMDCHFC-FNNRMPLTPCTVTLNLD-GSVWVMVKEPMRGMATGQFAVLYKGHECLGSGKIIRLGPTKFALQKDQSNTNCLHKDTNQQH-----PEPHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5B6-1", "uniprot_id": "MTU1_DROME", "id": "Q9W5B6-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "------------------------MIRNVVVGVSGGVDSAVSAHLLAEQGFKVLGVFMRNWD---EADEVG-RCSGEADLKDAEWACRQLGVELRQVNYVREYWTAVFSQFLDDYQMGLTPNPDILCNRHIKFDLFHKHALENLGYD--AVATGHYARNSLGN---------------YLEGIASNNDARLLIPADTFKDQTFFLAGISRKALQRTMFPLGDFQKSQVKDLAKKIGFQRLAKKKESTGICFVGKRNFKDFIQ------------------------EYITSKRGPFLDID----SGAVVGHHEGIHQWTVGQRCRLSS------FLQPYFVARKEAASNTIYVASGHNHPALLSTHIAVDPPNWLCS--KSQQILSDTGSLRCRFR-FQHTKPLVDCQLSISPS-NTFLVELDAPLRAITPGQYAVFYDDTACLGSARILSANP----LKKKNAQTQQAQAANLVS-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12093-1", "uniprot_id": "MTU1_YEAST", "id": "Q12093-1", "name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "aln": "MLARYLNLIGRRSASPYRPQRLPAKFDNVIVAMSSGVDSSVAAALFAGEFPNTRGVYMQNWSESQSLDDPGKEPCYERDWRDVNRVAKHLNIRVDKVNFEQDYWIDVFEPMLRGYSEGSTPNPDIGCNKFVKFGKLREWLDEKYGTGNYWLVTGHYAR--------------------VMQEMNGKGLFHLLRSIYRPKDQSYYLSQINSTVLSSLLLPIGHLTKPEVRDLAKYAGLP-TAEKPDSQGICFVNNSQHGKFKN---------------------FLKHYLPSSPGDIITVDPQSGAKTTWGRHDGLWSYTIGQKVGISMPQADPNYQGTWFVSEKLRDTNEILIVRGRDNPALYSDTMRIENFSSLGPREDTINAFQNTGALTLQFRSLQVPVQIKSCKLNRSADNLDITIHLASKQRAITPGQSCCLYIDDRVLGSGPIS---------HVNNNDTHA-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: .:*.****:*:* *: :. **:*:**. . :: * : * .*. ..: *.: . :*.: ::** **. :* *. * ****** **:.:** : . :. * . :.****** : : . :* ***:::*: :. .* ::*:. : * *:.:* : :* :* *:**:.: : .* .*: . * :: :: * *.* *:**: :. .::* * . : : :*** : . : .. : : :* :. : * :. . . . : *.:: ** . :* . ***. * : : : ", "identical_positions": 82, "similar_positions": 118, "identity": "16.84%" }, { "cls_id": "homologset.agr.SGD:S000002193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVG1-1", "uniprot_id": "GP157_RAT", "id": "Q5FVG1-1", "name": "G protein-coupled receptor 157", "aln": "------------------------------------MPTPAPPTELLPWERAVVLLSCVLSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQD-----------FAGTSWDCVLQGALSTFANTSSFFWTVAIALYLYLNIVR----------ATRGPCTDHLVWA---FHLISWGVPLAITVAAVCLKKIGYDASDVSVGWCWINLEAE-------------------DRVLWMLLTGKLWEMLAYILLPLLYLLVRKHINRAHQ---------ALSEYRPIWE--GRQ-LQRGSPTSMADKKLILIPFIFICLRVWSTVRFVLTLCGSP--------------VVQAPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCYP--RPPTQNPPG---ASIPPKMGESQESRRTP-EVPST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C206-1", "uniprot_id": "GP157_MOUSE", "id": "Q8C206-1", "name": "G protein-coupled receptor 157", "aln": "------------------------------------MPSPAPPTELLPWERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQD-----------FAGTSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVR----------TTRGPSTDHLIWA---FHLISWGVPLAITVAAVSLKKIGYDASDVSVGWCWINLEAE-------------------DRVLWMLLTGKLWEMLAYILLPLLYLLVRKHINRAHQ---------ALSEYRPICE--GRQ-LQRGSSTSTADKKLVLIPLIFICLRVWSTVRFVLTLCGSP--------------AVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCP--RPSTQSPPG---APTPPKIGESQESRRTP-EVPST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5UAW9-1", "uniprot_id": "GP157_HUMAN", "id": "Q5UAW9-1", "name": "G protein-coupled receptor 157", "aln": "------------------------------------MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQN-----------FAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVR----------AARGPRTDRLLWA---FHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAK-------------------DHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHT---------ALSEYRPILS--QEHRLLRHS--SMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSP--------------AVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3X9M9-1", "uniprot_id": "G3X9M9_MOUSE", "id": "G3X9M9-1", "name": "", "aln": "--------------------------MAFPLETSRLEGRWEP---LFPAIQWIQFAVATLSVIGSSSLLTYIAFQSPQKSAEIKPLLYLSFSDLLLGICWLVKALLYGT--------AAAHKDSICYNLQTVGEIFYLASLLYTVSYIWCLYSELRRKSGQSER---STVAQVTDYVCQGGHILFLLSSLIPPLLMTPVFLLGNVNECFHNFSESHRCILMHSPP------------SATPEPLPSTNTSVCSTLYFYGVTIFLASFFFSFLTIMVLLVH---------AQMLYKKFVKSTGLLESEQWAVIHTVGQRVRFFPVAFVCCWGPAVTLLIMKLTEPQ-------------ETFLHMALSVLQALTAASQGLLNCGIYGWTQCKFQQIKREPHRDADTQTPLLCSQKRIYSRSPNLLESPLALASSSSTVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LUC5-1", "uniprot_id": "A0ABK0LUC5_RAT", "id": "A0ABK0LUC5-1", "name": "", "aln": "-------------------------MLGADLGSPRLLVIILHACFLFPAIQWIQFAVATLSVIGSSSLITYIVFQNPQKSAEVKSLLYLSFSDLLLGICWLIKALVYGT--------AAAHKDSICYNLQTAGEIFYLASLVFTVSYIWCLYAELRRKHSPSEQ---STAAQVTDYACQGGCVMFLLSSLTPLLLMTPVFFLGNVNECFHNFSQNHRCMLMHS------------------EPLPSTNTSVCSTLYLYGVTVFLASFFFSLLTIVVLLVL---------AQTLYKKFVKSMGLLESEQWAVIHTVGQRVRFFPAAFVCCWGPAVTLLIMKLTKPQ-------------ETSLHVALSVLQALTAASQGLLNCGIYGWTQCKFQQIKREPPRDADTQTPLLCSQKRVYSRSPSASRPPLAFASSSSTVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BGS3-1", "uniprot_id": "TM116_DANRE", "id": "A2BGS3-1", "name": "Transmembrane protein 116", "aln": "-----------------------MDIFGENKTQMNTTTPTENWTSVYSIVRWIQMTMAVLSILGAGSIILYAAFQRLVKKPEVLPLFLLSLTDLLLALSWLCGGLLF-T--------QSCNSYATCYNLHIVEQTLYMASFFYTLHYVWVLYTGLNGKYHRRLNGFPAEAARTRNCRCLG----PVLSCLLPLLLTAPVFVAGNVFQCYTNFTQPYRCLLMHTG-------------AVYLTSSASPELTACSIIQEYCMAIFLGTFLITIVGMSIFMGK---------ARSLYKRVVTSQGFFGGSHWTTLRLLERRMVLYPSAFFFCWGPALLLATMMLVKPDV-----------IEGKMGVALYILQAFTSASQGLLNCLVYGWTQKHFRSLSSSTVRDANTQTPLLRSQKPNY--------AALHSAASLTNFV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12361-1", "uniprot_id": "GPR1_YEAST", "id": "Q12361-1", "name": "G protein-coupled receptor GPR1", "aln": "MITEGFPPNLNALKGSSLLEKRVDSLRQLNTTTVNQLLGLPGMTSTFTAPQLLQLRIIAITASAVSLIAGCLGMFFLSKMDKRRKVFRHDLIAFLIICDFLKAFILMIYPMIILINNSVYATPAFFNTLGWFTAFAIEGADMAIMIFAIHFAILIFKPNWKWRN---KRSGNMEGGLYKKRSYIWPITALVPAILASLAFINYNKLNDDSDTTIILDNNNYNFPDSPRQGGYKPWSAWCYLPPKPYWYKIVLSWGPRYFIIIFIFAVYLSIYIFITSESKRIKAQIGDFNHNVLEEEKEKKKLFGLGHWGKAKWYFRSYFKLPLLHLLRNLKNFFTISFIDPNEETDDSGSSNGTFNFGESSNEIPTLFRKTNTGSDENVSASGGVRLLDYNSAKPLDMSKYAMSEQPDLERNNPFDCENDITLNPSELVSKQKEHKVTFSVENEGLDTRKSSMLGHQTFSCQNSLESPLAMYDNKNDNSDITSNIKEKGGIINNNSNNDDDDNNNNNDNDNDNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNIKNNVDNNNTNPADNIPTLSNEAFTPSQQFSQERVNNNADRCENSSFTNVQQHFQAQTYKQMKKRRAQIQKNLRAIFIYPLSYIGIWLFPIIADALQYNHEIKHGPTMWVTYIDTCVRPLSCLVDVIVYLFKEKPWNYSWAKTESKYLIEKYILKGELGEKEILKFCHSNWGKRGWYYRGKWKKRKCWKYSTNPLKRILWFVERFFKQLFELKLHFSFYDNCDDFEYWENYYSAKDSNDNKRTESDETKTNSSDRSLPSNSLELQAMLNNITAEEVEVPLFWRIIHHIPMLGGIDLDELNRLLKIRYNNDHFSLPGLKFALNQNKSHDKHQDVSTNSMVKSSFFSSNIVTNDDENSIEEDKNLRYSDASASENYLVKPTIPGTTPDPIIEAQNDNDSSDSSGIDLIAFLRNGPL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : .:: . . : : : :: .: :* :: : .: . : : : . . :: * : .. : : : . . ::: . : . . : : * .. : ::: : .. . * : : ", "identical_positions": 4, "similar_positions": 59, "identity": "0.41%" }, { "cls_id": "homologset.agr.SGD:S000002194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACD4-1", "uniprot_id": "D4ACD4_RAT", "id": "D4ACD4-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "--MTPSYRDPEAACHAVMWRSVPGCLRYIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAD-------GLKALIEQNGDTGSDTRGEPHLELLEPAT-------------------------------------------------------------------------------------------------------------VGKQVPESGEQAQGGEEQLPGNGEQAPTPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLAYYEAAVRAGRLHLNEEPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENDDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVG---VCRVDPQ-GKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCEGDLA---------PG------LIDSTAPSSELGKD-----SLEG---LATAAQKIDG-------------MVDEASQHPDT----PGKAAKADVS--------QQTDPLCAECR-VLRQDPLPQDLVMFLHALRYKGPDFEYVSPIPAWAQADWQED-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149F1-1", "uniprot_id": "RUSD2_MOUSE", "id": "Q149F1-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWRGVPGCLRDIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAG-------GLKALVQPNGDAGSNTSGEPLLERLEPAA-------------------------------------------------------------------------------------------------------------VGKQVPESGDQAQGGEGQLPSNGEQTPAPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLSYYEAAVRAGRLHLNEEPVQDLSIVLKDNDFLRNTVHRHEPPVTAEPIHLLAENNDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVG---VCRVDPR-GKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCESDLT---------PG------LIDSTAPSSELAKD-----SLEG---LATAAQKIDG-------------IAEAAPQHLDT----PEKAAKADVT--------QETDPLCAECR-VLRQDPLPQDLVMFLHALRYKGPDFEYVSPIPAWARDDWQED-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZ73-1", "uniprot_id": "RUSD2_HUMAN", "id": "Q8IZ73-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWLDRRGWLRVLGHWRYDLRRPS-FTRTWSGDKGPMAETVSTQVGTEG-------GLRASHQQNGDAGGDAKVE--LSPGPPKP-------------------------------------------------------------------------------------------------------------AGREVEP-----------APVGGEHPSAAAPG------PGKHKKRRG----ATRERVVPPPKKRRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVG---VCRVDPR-GKPCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYN-SVAWGPSRGRGGYIP-KTNEELLRDLVAEHQAKQSLDVLDLCEGDLS---------PG------LTDSTAPSSELGKD-----DLEE---LAAAAQKMEE-------------VAEAAPQELDTIALASEKAVETDVMN-------QETDPLCAECR-LVRQDPLPQDLVMFLHALRYKGPGFEYFSPMPAWAQDDWQKD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3Z9-1", "uniprot_id": "A0A8M1P3Z9_DANRE", "id": "A0A8M1P3Z9-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "----------------MVHVWKITHIQALTLLRFGRRQNSEFIKRVYQNRNVSVETQRTHCSVLN-------VRRNSTQVES---SKHPVNTHLSLYDMDN-------------------------------------------------------------------------------------------------------------KGEEGGGDTDSTVKTSCGKRKNEETDEAAGQC------SGRKRKRGGGKQLRPGERYVPPPQKRNTGVSFNQEHFAETSYYFEGGLRKVHPYYFDFKSYCKGRWIGKTLLDVFKKEFRAESLDYYNAAVKEGRIKLNETPVDDLNVVLKNNDLLRNTVHRHEPPVCGQPLKLLVDDGEVVVVDKPSSLPVHPCGRYRHNTVIFILGKEKGLVGLHTVHRLDRLTSGVLLFARTLEVSKKLDVMVRERQLEKEYVCRVEGEFPEAEVVCEEPILVVSFRVG---LCRVDPK-GKESRTIFQRLSFNGRSSVVRCRPLTGRTHQIRVHLQFLGFPILNDPIYG-SSAWGPNRAKGGLVG-MSDEELLEALIEEHRSKESLHLLDLPDEEVSGKTKCKDGAQGRNEQITAIESSSGSSEVSLD-----EVKAESRQVVQQSTSES-------------VGEINGARKDK-DLASDDASRTGRSKD------FVRDHLCGECK-IVRPDPTEKELIMYLHALRYKGPDFEYSTQLPDWAKEDWIQD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKU8-1", "uniprot_id": "Q9VKU8_DROME", "id": "Q9VKU8-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MESS-------------------KLLRNAQTQHGDASSVD--VENIFLHR----HMLYTNPTSD----------------GNLHDREDSPECVWCPDDKDG-----------------------SPAE------------------------------------------------------------------------------------SKDPP-----------ISISEEKSETQSKE----VLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEKVP-KDYKIKHNDLLANVVHRHEVPVTSQPIKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEKIDVVSYKIG---VCKVSPK-GKDCKTTFKRIGEVGSDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYN-HEVFGPLKGRGGDIGGITEEQLISNLISIHNAENWLGLE--GDQIVSG--EIKDVAAS-----TSVV-EAPSVVQAP-----INSETEKPVISKNLEPSN--------------DATAQIATQTCYEEPDRSFDS---------KKTTSDPQCSECK-INYRDPGTKDLIMYLHAWKYKGVGWEYETELPEWACNSNIDYDKV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKV0-1", "uniprot_id": "Q9VKV0_DROME", "id": "Q9VKV0-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MQNSPAPCAWYLPWSLAAQQHQQKMLQMQSPFLDKMGATS--VGGIFAGQPQMQQQLSPNTAAAPPANYQQPALHPSAAPGAPHFHMGSPYSHLAPQLLNAGQLNQNALMHSAMFSSLPLGAYYAPAAGAGHSAFGGVPLTTAAQQSLLAATGGATAGHLANQQTTAQVPVQVPVQMAQRTAPAACSMVQPLNCLPHQELNHLSSINLNLLRSPAPPLPAIQVLPSAEVPINKKTTSPRDSENLKIKVPEKRKTDDNDQIKELKKAKLETKALKAKRPGFTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERCIQTGTLTVNFEKVP-IDYRLKHNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIG---VCKVSAK-GKDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYN-HEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGID--CDSDISMFKSTKDEADR-----ESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEYQVAAQKSSSEICPAPLDAVESPLNGGGCNVGKVTVDEHCYECK-VHYRDPKSKDLIMYLHAWKYKGPGWEYETELPNWARNDWDHLDSA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12069-1", "uniprot_id": "PUS9_YEAST", "id": "Q12069-1", "name": "tRNA pseudouridine(32) synthase, mitochondrial", "aln": "-------------------------------MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAG--------NATSNEFDEHLQNEVERE-----------------------------------------------------------------------------------------------------------------------------------------REIQKKKKIKRTQS---------KKSPDLINKSTFQSRTIGSKKEKHR------QLDPEYEIVIDGPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHIN-DETADLSTVIRNGDLITHQVHRHEPPVTSRPIKVIFEDDNIMVIDKPSGIPVHPTGRYRFNTITKMLQNNLGFVVN-PCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVGEFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRISYDGKTSIVKCKPLTGRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAKSWFHSNGGYGEVLR------------------------------------------------------------------------------------------------------QEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWCYKTEYPEWALRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : :: . : . : : * ::. ***: **.* : :: * ** ...::.:* *** *: :. * : :* . . ::..*:: : ***** ** .*:::: : :::*::**:.:**** **:*.**: :* :: : . :********::::.:: : .: :: *:: ***:.:* * ** * :: : ::. ::. :*::. : .* . * *:::. * *:* *:***** ********:**.** ***:*. .:* .:.* : : : ::. : : : * *. ** ::* ::*** *:. * : *. ", "identical_positions": 98, "similar_positions": 129, "identity": "12.95%" }, { "cls_id": "homologset.agr.SGD:S000002198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RC73-1", "uniprot_id": "M0RC73_RAT", "id": "M0RC73-1", "name": "", "aln": "---------MPCVQ-LPAKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFADHGETLAMKGLTLNCLGKREEAYEFVR---KGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQVPPNK-IAYEYSELLLYQNQVMREAN-----LFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFKNLIDWNAENWCYYEGLEKALQLR-SLDERLQIYEEISKQHPRAVSPRRLPLNFVPG-KKFQELMDKFLRPNFSKGCPPLFTTLKSLYCNTEK--VSIIQELVTNYEASLKMNGFFSPYENGE---KEPPTTLIWVQYFLAQHFDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLREAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTR--EGTSAMENLNEMQCMWFETECISAYQRLGR--------------------------------------YGDALKKCHEVERHFVEITDDQFDFHTYCMRRMTLRAYVDLLRLEDTLRRHTFYFKAARSAIEIYLKLHDNPLTSDSKQQDIDSENLSAKELKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGH--KEELIPEKLERVDNPLEE-AIKFLTPLKTLAADNIYTHLLAFEIYFRKGKFLLMLQSVKRAFAIDSNNPWLHECLIKFSK-SVSNHSN--LPDIVSTVLAQEMKKIFVDKDVHSFNEDFLKHNATSLQHLLAGAKMMYFLDKSRQEKAIATATRLDETIKNKNVKTLIKVSEALQDGSFG-NCSSQYEEYRKTCHNLFPLTPAFLP-AANEALGLSTELNHT-AEHKLLTNEI-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBB4-1", "uniprot_id": "NAA16_MOUSE", "id": "Q9DBB4-1", "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "aln": "---------MPCVQ-LPAKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLILNCLGKREEAYEFVR---KGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQVPPNK-IAYEYSELLLYQNQVMREAN-----LFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKALQLR-SLDERLQLYEEVSKQHPRAVSPRRLPLSFAPG-KKFRELMDKFLRPNFSKGCPPLFTTLKSLYCDTEK--VSIIQELVTNYEASLKMNGYFSPYENGE---KEPPTTLIWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTR--EGTSAMENLNEMQCMWFETECISAYQRLGR--------------------------------------YGDALKKCHEVERHFLEITDDQFDFHTYCMRKMTLRAYVGLLRLEDALRRHTFYFKAARSAIEIYLKLHDNPLTNDSKQQDIDSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGH--KEELIPEKLERVDNPLEE-AIKFLTPLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRAFAIESNNPWLHECLIKFSK-SVSNHSN--LPDIVSKVLAQEMKKIFVNKDLHSFNEDFLRHNATSLQHLLAGAKMMYFLDKSRQEKAIATATRLDETIKNKNVKTLIKVSEALLDGSFG-NCSSQYEEYRKTCHSLLPLTPAFLP-AAREALGLSAELNHT-ADHKLLMNEI-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6N069-1", "uniprot_id": "NAA16_HUMAN", "id": "Q6N069-1", "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "aln": "---------MPNVL-LPPKESNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVR---KGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNK-IDYEYSELILYQNQVMREAD-----LLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQIS-TLEERLQIYEEISKQHPKAITPRRLPLTLVPG-ERFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEK--VSIIQELVTNYEASLKTCDFFSPYENGE---KEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHIGNLKEAAKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTR--EGTSAMENLNEMQCMWFQTECISAYQRLGR--------------------------------------YGDALKKCHEVERHFFEITDDQFDFHTYCMRKMTLRAYVDLLRLEDILRRHAFYFKAARSAIEIYLKLYDNPLTNESKQQEINSENLSAKELKKMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGL--KEELIPEKLERVENPLEE-AVKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINSNNPWLHECLIRFSK-SVSNHSN--LPDIVSKVLSQEMQKIFVKKDLESFNEDFLKRNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDETIKDKDVKTLIKVSEALLDGSFG-NCSSQYEEYRMACHNLLPFTSAFLP-AVNEVDNPNVALNHT-ANYDVLANEI-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80UM3-1", "uniprot_id": "NAA15_MOUSE", "id": "Q80UM3-1", "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDK-VDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPGNWAYYKGLEKALKPA-NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSG-EKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEK--VAIVEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYVLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGP--KEELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSGHPWLHECMIRLFH-SVCESKD--LPETVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCDGSLG-DCKEAAEAYRASCHKLFPYALAFMPPGYEEDMKITVNGDSS-AETEELANEI-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD89-1", "uniprot_id": "D3ZD89_RAT", "id": "D3ZD89-1", "name": "", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDK-VDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPA-NMLERLKIYEEAWTKFPRGLVPRRLPLNFLSG-EKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEK--VAIVEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGP--KEELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFN-SVCESKD--LPEAVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMIYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCGGSLG-DCKEAAEAYRVSCHKLFPYALAFMPPGYEEDMKITVNGDSS-AETEELANEI-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXJ9-1", "uniprot_id": "NAA15_HUMAN", "id": "Q9BXJ9-1", "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDK-VDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPA-NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSG-EKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEK--VAIIEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGP--KEELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKD--LSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGSLG-DCKEAAEIYRANCHKLFPYALAFMPPGYEEDMKITVNGDSS-AEAEELANEI-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE25-1", "uniprot_id": "F1QE25_DANRE", "id": "F1QE25-1", "name": "", "aln": "---------MPSIT-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNSKFAEHGETLAMKGLTLNCLGRKEEAYDLVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKIVEEFRKTQQTSPDK-VDYEYSELLLYQNQLLREAE-----LFKEALDHLTSYEKQICDKLAVEETRGELLLKLDRAGEATEVYHRLLERNPENWSYYQGLEKALKPK-SAEDKQKIYEDAWVKYPKGLVPRRLPLSFLTG-EKFRECLDRYLRMNFSKGCPPVFTTLKSLYHHKDK--VAIIEELVVGYDKSLKTCKMFNQNDDGK---IEPPTTLLWVQYFLAQHFNHIGKHTVALEYINTAIESTPTLIELFLIKAKIYKHAGNIREAARWMDEAQALDTADRFINSKCAKYLLKAGLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECALAYKSLNK--------------------------------------YGEALKKCHEIERHFVEITDDQFDFHTYCMRKMTLRSYVDLLNLEDVLRMHPFYFKAARTAIEIYLSLHDNPLSDDNKESQADNANLTDKELKKLRNKQRRAQKKAQLEEEKKNAEKEKQLKNQKKKKEEDEEEIGGP--KEELIPEKLAKIENPLEE-AVKFLTPLKNLVKNKIETHLLAFEIYLRKEKYLLMLQSVKRAYSLDPDHPWLHQCLVRFFK-GVSDSKD--MPEAVQTVLKQEITKLFGESDPKTFNKNFLSKHANSIPHRVAAAKMMVFLDSSSEGKAAELATSLNESLTDRSLQTCAEVLQALRDGSLGSQQEKFTESYRVSCHGLYPYAVAFMPPGYQDNTAVTTNGDLSPCDHEDLPNEM-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWI2-1", "uniprot_id": "Q9VWI2_DROME", "id": "Q9VWI2-1", "name": "", "aln": "---------MPSSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREEAYKYVR---LGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRDLEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQSQ-TSIEA-HDYRHSELLLYQNQILIESN-----RLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVLYYEQYIAARQVT-DSSAVVSIYRVFQEQYPRALCPRRLPLNIANG-DEFRVVTDEYLRRGLRKGIPPLFVNVRTLHQIPER--AAVIEELALQYFENLTRSGHFSREDADAGIPVEPASALVWTALFLAQHYDYMRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKYMLRANMVQEAEEICAKFTR--EGVSAMDNLNEMQCMWFQTECALAYQRMGR--------------------------------------WGESLKKCHEVERHFAEIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEEIDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDELVAEKLERTDDPLDK-AIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDASHPVIHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLYEGARSLYELDNSKKAAAIKLVTSFN--LAKLRLEEATKIYTALRDGDVFGECEAEAASYQQACHQRFQYARIFRNVEELEAQLQEKEAAKLRAEEEQQQLIHVDSSEPVSVLATAAAAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12945-1", "uniprot_id": "NAT1_YEAST", "id": "P12945-1", "name": "N-terminal acetyltransferase A complex subunit NAT1", "aln": "MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILK--KDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPT--------------QDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKRKS-----DSLDENSDEIQNNGQNSSSQKKKAKKEAAAMNKRKETEAKSVAAYPSDQD---------NDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTP------FDPILKKVVTKSLEKEYSENFPLNEISNNS------------------------FDWLNFYQEKFGKNDINGLLFLYRYRDDVPIG-------------------------SSNLKEMIISSLSPLEPHSQNEILQYYL-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **. * . *: ** ***::.**: . **. * .* ::**:*** * :*.:::* . * :.. * :* ** *: *. *:*.*:** : **: . * ** :**: ** *: *::. :* : :*.* . *:: .: : : * . :. * : . *.:** ::*:*::: :: :: :.*: : : **: : * . : ::* : .* ::. * *. * **: : :* .*: *: :**.: . ..: .:: : :* *. * .::.*: . .:::::. * .* : . .::*. :*:**: : . * :**:..: ****:*: *.:* ** * * ::*.: :* **:**.* .**.*:*. :.:* *:.: **: :....:.:*: ::. ** .* ** : * :**: : : :.: :: :**:***:****: * *:*: :*. . * :.:*.:* : * ::*: ::*. *. .. : : .*::: .:. :***: * : . : . :: :::. *** . . *::. * :* . . : ::: **: * * * : .:.: . :. .: . . . . :* : . : . : : .: . : : . :: : . . : .: . ", "identical_positions": 159, "similar_positions": 270, "identity": "16.63%" }, { "cls_id": "homologset.agr.SGD:S000002200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ79-1", "uniprot_id": "SIR1_RAT", "id": "A0A0G2JZ79-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQAGGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAAAAAAAAAGCEAASAAAPAALWREAAGAAAASA-EREAPATAAAGDGDNGPGLR---REPRAADDFDDDE----GEEEDE-AAAAAAAAIGYRDNLLLADEIITNGFHSCESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQTIKNKVDDLEVSEPKSCVEEKSQEVQTYRNVESIN--------VENPDFKAVGSSTGDKNERTSVAETVRKCWPNRLAKEQISKRLD-GNQYLFVPPNRYIFHGAEVYSD----SEDDALSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGS--GADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923E4-1", "uniprot_id": "SIR1_MOUSE", "id": "Q923E4-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEVALALQAAGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEP--SAAVAPAAAGCEAASAAAPAALWREAAG-AAASA-EREAPATAVAGDGDNGSGLR---REPRAADDFDDDE----GEEEDEAAAAAAAAAIGYRDNLLLTDGLLTNGFHSCESDDDDRTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--ILQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRPQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQATNNNVNDLEVSES-SCVEEKPQEVQTSRNVENIN--------VENPDFKAVGSSTADKNERTSVAETVRKCWPNRLAKEQISKRLE-GNQYLFVPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEAIATRQELTDVNYPSDKS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EB6-1", "uniprot_id": "SIR1_HUMAN", "id": "Q96EB6-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDED----DDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELAYLSELPPTPLHVSEDS----------------------SSPERTSPPDSSVIVTLLDQAAKSN-DDLDVSESKGCMEEKPQEVQTSRNVESIAE------QMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLD-GNQYLFLPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK34-1", "uniprot_id": "SIRT1_DROME", "id": "Q9VK34-1", "name": "NAD-dependent histone deacetylase sirtuin-1", "aln": "MMENYEEIRLGHIRSKDLG-------NQVPDTTQFYPPTKFDFG----------AEILASTSTEAEAEAEATATTTEPATSELAGKANGEIKTKTLAAREEQEIGANLEHKTKNPTKSMGEDEDD----EEEEEEDDEEEEE-----------DDEEGITGTSNEDEDSSSNCSSSVEPDWKLR-------WLQREFYTGRVPRQVIASIMPHFATGLAGDTDDSVLWDYLAHLLNEPKRRNKLASVNTFDDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGIQR--VIECHGSFSTASCTKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDA-----------SVAVTEEELRQLVENGIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIPSSIPATVPQILINREQLHHLKFDVELLGDSDVIINQICHRLSDNDDCWRQLCCDESVLTESKELMPPEHSNHHLHHHLLHHRHCSSESERQSQLDTDTQSIKSNSSADYILGSAGTCSDSGFESSTFSCGKRSTAAEAAAIERIKTDILVELNETTALSCDRLGLEGPQTTVESYRHLSIDSSKDSGIEQCDNEATPSYVRPSNLVQETKTVAPSLTPIPQQRGKRQTAAERLQPGTFYSHTNNYSYVFPGAQVFWDNDYSDDDDEEEERSHNRHSDLFGNVGHNYKDDDEDACDLNAVPLSPLLPPSLEAHIVTDIVNGSNEPLPNSSPGQKRTACIIEQQPTPAIETEIPPLKKRRPSEENKQQTQIERSEESPPPGQLAAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06700-1", "uniprot_id": "SIR2_YEAST", "id": "P06700-1", "name": "NAD-dependent histone deacetylase SIR2", "aln": "MTIPHMKYAVSKTSENKVS---NTVSPTQDKDAIRKQPDDIINNDEPSHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLNSLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTNVEDPLA---KKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYSKIKHLG--LDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLELPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCGWT--------IPHKKWNDLKNKNFKCQE-----------------------------------------------------------------KDKGVYVVTSDEHPKTL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . * . : : : :: : : . *. . *. : . .: . : * . . . * :: . : : . . . : : : . * : .. *::. :. :: .:**:********.* ******* :*:*::: * *** :*: : * :** *:::*. : * : * * ** : : :************.** ***. :::*****:**:* *::: : : .* :* ** * .. .::**:*.**** **:::* : * **** **:**** **: * . :* ***:****: : * .**:.*** .* * :.:: . .: .: :. : .. : ", "identical_positions": 113, "similar_positions": 121, "identity": "12.91%" }, { "cls_id": "homologset.agr.SGD:S000002201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62203-1", "uniprot_id": "SF3A2_MOUSE", "id": "Q62203-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEQVKVEVKKFVKIGR--------PGYKVTKQRDTEMGQQSLLFQIDYP-EIAEG---------IMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKF----------FFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPDALPPPPPGGLPLPPMPPTGPAPSGPPGPPQMPPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGVHP-APMPPMLRPPLPSDGPGNMPPPPPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXT8-1", "uniprot_id": "SF3A2_RAT", "id": "Q6AXT8-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEKVKVEVKKFVKIGR--------PGYKVTKQRDTEMGQQSLLFQIDYP-EIAEG---------VMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPDALPPPPPGGLPLPPMPPTGPAPSGPPGPPQMPPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPVVHPPTSGVHPPAP-------GVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP-------GVHP-TPMPPMLRPPLPSDGPGNMPPPPPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15428-1", "uniprot_id": "SF3A2_HUMAN", "id": "Q15428-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEKVKVEVKKFVKIGR--------PGYKVTKQRDSEMGQQSLLFQIDYP-EIAEG---------IMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP---------------------GVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPP-GVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VU15-1", "uniprot_id": "Q9VU15_DROME", "id": "Q9VU15-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQNRAGGKTGSGGVASWSETNRDRKERLRQLALETIDLN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQDNLARRAAKEAKEAPSSLLAPEKPRVEPKKFVKIGR--------PGYRVTKQRELSNGQQSLLFQVDYP-EITES---------IVPRHRFMSAYEQKIEPPDRKWQYLLFAAEPYETIGFKVPSREVEKSEGKFWTHWNRDTKQFFLQFAFKFEPKILPP-----------PPPNLHRALGP------------PGGFPMP-------------------------GPPRPAMHPMFNGVHPPPPMLSNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07350-1", "uniprot_id": "PRP11_YEAST", "id": "Q07350-1", "name": "Pre-mRNA-splicing factor PRP11", "aln": "MNYLEGVGSKKGGGGIASESQFNLQRRKEVESLLSKGENVPYTFQDEKDDQVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIEKSSLGREGQTTHDFRQQQKIIEAKQSLKNNGTIPVCKIATVKNPKNGSVGLAIQVNYSSEVKENSVDSDDKAKVPPLIRIVSGLELSDTK-QKGKKFLVIAYEPFENIAIELPPNEILFSENNDMDNNNDGVDELNKKCTFWDAIS------------------------------------------------------------------------KLYYVQFFFKQAEQEQADV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . *.*.*.**:** *: * :*::.:..* : :: .:**: *** *. **** *:* . .* * **** *: **. . *.: . : : :*::: : * :::. :: . *. .* :*::*. *: *. : * *::*. * :: ::*::* **:*.*.:::*..*: :*.: : : * :: . .. . : ", "identical_positions": 56, "similar_positions": 84, "identity": "10.83%" }, { "cls_id": "homologset.agr.SGD:S000002203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4P4-1", "uniprot_id": "FAD1_RAT", "id": "D4A4P4-1", "name": "Bifunctional FAD diphosphatase/FAD synthase", "aln": "-------------------------------------------------------------------------------------------------MASRASELPPG--RSVTAGIIIVGDEILKGHTQDTNTYFLCRTLRSLGVQVCRVSVVPDEVATIASEVTSFSRRFTHVLTAGGIGPTHDDVTFEAVALAFGEELKPHPELQAAIKTLGG-----EGWEKLSMVPSSARLHYGTDPGTGHPFRFPLVSVRNVYLFPGIPELLRRVLEGLKGLFQNTAVQFHLKELYVAASEGSIAPILSEAQAHFGRRLNLGSYPDWSSNYYQVKLILDSEEKEPLEECLAYLTARLPQGSLIPYLPDAVEKASEAVYKLAESGSCLGKKVAGALQTIETALAQYHLSQICVGFNGGKDCTALLHLFHAAVQRKFPDVPKP--------------LQILYIRSISPFPELEQFLQDTIKRYNLQMLEAEG------NMKQALGELQGKHPQLEAVLMGTRRTDPYSCSLHHFSPTDPGWPSFMRINPLLDWTYRNIWEFLRQLFVPYCILYDRGYTSLGSRENTKQNPALKCLSPG----------------------------------------GHPVYRPAYLLENEDEERNSRM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R123-1", "uniprot_id": "FAD1_MOUSE", "id": "Q8R123-1", "name": "Bifunctional FAD diphosphatase/FAD synthase", "aln": "-------------------------------------------------------------------------------------------------MASRASELPPGSGRSVTAGIIIVGDEILKGHTQDTNTYFLCRTLRSLGVQVCRVSVVPDEVATIASEVNSFSRRFTHVLTAGGIGPTHDDVTFEAVAQAFGEELKPHPELQAAIKTLGG-----EGWEKLSMVPSSARLHYGTDPRTGHPFRFPLVSVRNVYLFPGIPELLRRVLEGLKGLFQNTAVQFHLKELYVAASEGSIAPILSEAQAHFGRRLSLGSYPDWSSNYFQVKLILDSEEKEPLEECLAYLTARLPQGSLVPYQPDAVEKAGEAVYKLAESGSCLGKKVAGALQTIETALAQYHLSQLCVGFNGGKDCTALLHLFHAAVQRKFPDVPKP--------------LQILYIRSISPFPELEQFLQDTIKRYNLQVLEAEG------NMKQALGELQEKHPQLEAVLMGTRRTDPYSCSLSHFSPTDPGWPSFMRINPLLDWTYRNIWEFLRQLFVPYCILYDRGYTSLGSRENTTQNPALKCLSPG----------------------------------------GHPVYRPAYLLENEDEERNSRM------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFF5-1", "uniprot_id": "FAD1_HUMAN", "id": "Q8NFF5-1", "name": "Bifunctional FAD diphosphatase/FAD synthase", "aln": "MGWDLGTRLFQRQEQRSRLSRIWLEKTRVFLEGSTRTPALPHCLFWLLQVPSTQDPLFPGYGPQCPVDLAGPPCLRPLFGGLGGYWRALQRGREGRTMTSRASELSPG--RSVTAGIIIVGDEILKGHTQDTNTFFLCRTLRSLGVQVCRVSVVPDEVATIAAEVTSFSNRFTHVLTAGGIGPTHDDVTFEAVAQAFGDELKPHPKLEAATKALGG-----EGWEKLSLVPSSARLHYGTDPCTGQPFRFPLVSVRNVYLFPGIPELLRRVLEGMKGLFQNPAVQFHSKELYVAADEASIAPILAEAQAHFGRRLGLGSYPDWGSNYYQVKLTLDSEEEGPLEECLAYLTARLPQGSLVPYMPNAVEQASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNP--------------LQILYIRSISPFPELEQFLQDTIKRYNLQMLEAEG------SMKQALGELQARHPQLEAVLMGTRRTDPYSCSLCPFSPTDPGWPAFMRINPLLDWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENTVRNPALKCLSPG----------------------------------------GHPTYRPAYLLENEEEERNSRT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EH8-1", "uniprot_id": "FAD1_DANRE", "id": "Q68EH8-1", "name": "Bifunctional FAD diphosphatase/FAD synthase", "aln": "-------------------------------------------------------------------------------------------------MAQNCNTSSTQKNGSATAAILIIGDEILKGHTVDTNSAFLCRGLRKLGITVERITVVPDVQEVIAKEVSQLSSTVTHLITSGGIGPTHDDVTFESVAMAFGEELYAHPEMTKLVEGFFGTVTSDSAPMKLAMVPASAKLNFGIDPQTGQRNRFPLVSVHNVYIFPGIPSLLEKSFNGLSHLFSGSGTTFHTREVFVNADETEIAQSLSKLQAGWGKRVSLGSYPDWLSNYHRVRLVLDTDSVEEVERARTQLIEELPKGSVVPLVTDPISVAAQEVYSLSKSETQLGKKVAAALGTIEMALDKYSVNEICVGFNGGKDCTALLHLYYAALKRRYPDGKDR--------------LKALYIRIVSPFPEMERFLQDTIKRYDLELFSVEG------SIRQALNEVKERRPDLRAVLMGTRRTDPYSHTLTPFCPTDPGWPDYMRVNPLLEWTYHDIWSFLRTLYVPYCILYDKGYTSLGSMDNSYRNPSLKMVDER----------------------------------------GATRYKPAYMLENEEEERNSRE------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJY1-1", "uniprot_id": "Q9VJY1_DROME", "id": "Q9VJY1-1", "name": "FAD synthase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLASQFWHTVCR---------HYRTSRWLHIPPVE-----------------------------------KSESNDQLRDKLEYTEEVIKRAMTLYKPNEMMLSFNGGKDCTVLLDILARMTPPSMP-------------------LGAVYVKSANPFEELEKFVDDCVQRYGLQLRRYEG------VLKVAFEQLIAEDSQVKAIFLGCRRSDPESCNLYELEPTNNGWPAMMRIFPLLEWSYHDIWNYLRSNNLPYCCLYDQGYTSLGDRSSTRVNPSLLAYDEKL---------------------------------------DKMTYRPAYELENVRLERFNRDEHGQASVSGSKQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYI5-1", "uniprot_id": "Q9VYI5_DROME", "id": "Q9VYI5-1", "name": "FAD synthase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYWRVTSSFLLARARPRLPQTLRPLSTMNECRKNITNITNITANN-----SILCAKSISKKHLFLEKRSMSDRSENSKDVAKGQDISNPMELT---------------------------------AEDRLAIEERQNKAFAFFAETLQIYGVEELIFCFNGGKDCTVLLDLLMRYLRQENISSGD---------------IPMLYIKSGDSFPEIDEFVERCVRNYRVQLVQYEG------TLKEALTHMSSDMPRIKAVFVGSRNTDPYCQHLAPMQPTDNDWPPMMRLNPLLEWSYHDVWHYIHLNSVPYCSLYDRGYTSIGNRANTVPNPHLRRTDAECECGSNSDAVCSC---------------------------DLGGYRPAWELQDATMERAGRLPRK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38913-1", "uniprot_id": "FAD1_YEAST", "id": "P38913-1", "name": "FAD synthase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLSKAAEMCYEITN--------------SYLHIDQKSQ---------------------------------IIASTQEAIRLTRKYLLSEIFVRWSPLN-GEISFSYNGGKDCQVLLLLYLSCLWEYFFIKAQNSQFDFEFQSFPMQRLPTVFIDQEETFPTLENFVLETSERYCLSLYESQRQSGASVNMADAFRDFIKIYPETEAIVIGIRHTDPFGEALKPIQRTDSNWPDFMRLQPLLHWDLTNIWSFLLYSNEPICGLYGKGFTSIGGINNSLPNPHLRKDSNNPALHFEWEIIHAFGKDAEGERSSAINTSPISVVDKERFSKYHDNYYPGWYLVDDTLERAGRIKN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. : : :: . :****** .** : : ::: ..* ::.*: ..* :.: : : *: .. . .*:.:* *.:** * : *: .** **: ***.* ::* :: * * **.:*:**:*. .: ** * . * *.: * : ** .* ", "identical_positions": 45, "similar_positions": 62, "identity": "6.76%" }, { "cls_id": "homologset.agr.SGD:S000002205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64620-1", "uniprot_id": "PPP6_RAT", "id": "Q64620-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQR6-1", "uniprot_id": "PPP6_MOUSE", "id": "Q9CQR6-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00743-1", "uniprot_id": "PPP6_HUMAN", "id": "O00743-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27884-1", "uniprot_id": "PPP6_DROME", "id": "Q27884-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MG--DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGGQVP-HTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYGNANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDPEDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGK-LVTVWSAPNYCYRCGNVAAILSFETAEKRQTKIFLAVPDA---ERVIPKQNTTP-YFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20604-1", "uniprot_id": "PP11_YEAST", "id": "P20604-1", "name": "Serine/threonine-protein phosphatase PP1-1", "aln": "MVSRGPDEWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAVPDDYIRESTANHNNQRAGYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *:::* : *: *.**::*:**: * ::*:**:*: **.*************:** :****.* .* . ****:**:************ *: **.::* :***:*****:****:****::** .***.:. *:** :***:**:**:** ::*********:* *****.:.* *:*::*.*.**:****:::: * ********** :*:.:* :*.*:**.****** ** *: * * :***************:*::: .. *:* **** * . .. . ***", "identical_positions": 173, "similar_positions": 80, "identity": "55.63%" }, { "cls_id": "homologset.agr.SGD:S000002209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38656-1", "uniprot_id": "LA_RAT", "id": "P38656-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVDTPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHG--EIKWIDFVRGAKEGIILFKEKAKDALEKARSANNG-NLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHR--------RGPVKRGIDGRDREEPASKHKKRENGARDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32067-1", "uniprot_id": "LA_MOUSE", "id": "P32067-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVEIPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHG--EIKWVDFARGAKEGIILFKEKAKEALEKARNANNG-NLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRR--------RGPMKRGRDGRDREEPASKHKKRENGARDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05455-1", "uniprot_id": "LA_HUMAN", "id": "P05455-1", "name": "Lupus La protein", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLEDKGQVLNIQMRRTLHK-----AFKGSIFVVFDSIESAKKFVETPGQK-YKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHG--EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG-NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKG----------------RRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQB7-1", "uniprot_id": "A0AC58JQB7_DANRE", "id": "A0AC58JQB7-1", "name": "", "aln": "MQLHEARSPKPELVPVNVYDRSCVLCTICTQAMHMFSVLLKRNKITTELWPVSCCLTGGVIGVDGYTVIQRSTNEVMFVVILAKMADNQEMSPLEKKVAEQIEYYFGDHNLPRDKFLKEQLQLD-DGWVPLETMLKFNRLKSLTSEESVIVESLLKSKTGLLEISEDKTKIRRDPNKPLPENNEEYRDALKHKSIYMKGFPLETTLD--------DVKEWLADKGTFENIYLRKGPQK-----TFKGSIFAVLETEEAAKAFVERDDIKNFKGNEMIVMMKDAYFTKKIAERKQNRVESKAKAKCDKEEKQKQAEEEEMKSLNEQRGCLLKFSGELG-QTSREDFHSVFSDHA--QIKWIDFTRGAKEGTILFHSNAKEALQKVREALNGEDPKVKEQAVQWEILEGDVEMETLKKIIEDQQESINKRKGGRG----------------GFRGRGRGRGGRRDRGGREHTQFKGKKTKFDSDEEGDEESASTKKRPLESNRQ--DNGEPVSKQAKSENGS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40796-1", "uniprot_id": "LA_DROME", "id": "P40796-1", "name": "La protein homolog", "aln": "--------------------------------------------MAEVAETPSVEAQEEVAQPAEAQVLEAKNGDAKKDPAPAAEEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLDSQIS--------ELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIV-YKERELLRKWQVDYLKEKQEEYAQKNEKRKNKKEAKPEP-----------AFELPKNAIVVFEGAPE-TSSREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEKYIAKVEEGK-LKFKDEVSLSLRKATEEEEKEFIDKAIEFMKKRRDFTRNKGK----------------RFNRKRHGGNDHKHGG--------GKKARGD-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33399-1", "uniprot_id": "LHP1_YEAST", "id": "P33399-1", "name": "La protein homolog", "aln": "-----------------------------------------------------------------MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKN-DGWVPISTIATFNRMKKYRP-VDKVIEALRSSE--ILEVSADGENVKRRVPLDLTAARN-ARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNK----KFNGTVLVEFKTIPECEAFLKSYSND-DESNEILSYEGKKLSVLTKKQFDLQREASKSKN----------------------------FSGRSR-----------------------SFNGHKKKNLPKFPKNKKKNGK-------------------------EESKEDSSAIADDDEEHKE-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*:*:**.: *: *:**: : :****:. : .*:*: . . :: :* .*: ::*:* * .::* :. : : :.:: .** : :: : . . . :: :*: : *:*::: :.: .: *:. : ::: . : .. * : *.* .* .:. : . . . : . : :: : ", "identical_positions": 30, "similar_positions": 86, "identity": "5.74%" }, { "cls_id": "homologset.agr.SGD:S000002210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35083-1", "uniprot_id": "PLCA_MOUSE", "id": "O35083-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MELWPGAWTALLLLLLLLLS---TLWFCSSSAKYFFKMAFYNGWILFLAILAIPVCAVR--GRNVENMKILRLLLLHAKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLP--DRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTR--NHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRFTSPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLTIFREISTDGLGGGDCLKKPGGAGEARL---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99943-1", "uniprot_id": "PLCA_HUMAN", "id": "Q99943-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "aln": "MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR--GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP--GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTR--NHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTS-GQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K3K7-1", "uniprot_id": "PLCB_MOUSE", "id": "Q8K3K7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "MDPWP--WLTAALLLLLLLV------QLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGRTVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTS-GTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENS-AIKEPGVLPAQ-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AC45-1", "uniprot_id": "D4AC45_RAT", "id": "D4AC45-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "--------MGAAG-------------RLNRTARFYVKVGLYCVLCLSFSAAASIVCLLRHGGRTVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTS-GTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISEIPQENS-TIKESGVLPAQ-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15120-1", "uniprot_id": "PLCB_HUMAN", "id": "O15120-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "MELWP--CLAAALLLLLLLV------QLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP--ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTS-GTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENG-ATAGSGVQPAQ-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYJ4-1", "uniprot_id": "Q9VYJ4_DROME", "id": "Q9VYJ4-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "MITMTSFIELLGLFLLLMLP---FLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTR--PCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTR--RNTGALHPFKKGAFHMAIDQQIPILPVVFSSYCTFLNDKKKILNS-GRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYKPIKKVGIPAASSASTSSTTTTTLASPGTAVTPVADAAVAAAAAVASSSSAYGQPPGYEAGAAKASLLKTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTI0-1", "uniprot_id": "Q7KTI0_DROME", "id": "Q7KTI0-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-MACTCEVIGLACVVALILS-------ATAKAPYQMRMFFIFFGAGLIVFLCVPFMILR--PRDYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTR--NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYS-FMDDEKKTFRP-GHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKEGQALSSKKQA------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33333-1", "uniprot_id": "PLSC_YEAST", "id": "P33333-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-------MSVIGRFLYYLRS---------------VLVVLALAGCGFYGVIASILCTLIG-KQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAK-KPYIMIANHQSTLDIFMLGRIFP--PGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNR-GCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . *: :: . ... ::: **** :*: : : .. :*:.: : * * * :::* : : : . : . : ::***** : ***:*:*::* : : *: *:* *. : : : * : * :.*. . .: : : * . ", "identical_positions": 30, "similar_positions": 60, "identity": "8.55%" }, { "cls_id": "homologset.agr.SGD:S000002213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTZ7-1", "uniprot_id": "GMPPB_MOUSE", "id": "Q8BTZ7-1", "name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "aln": "----------MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTG-RIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLKPTSIEKEIFPVMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKHPERLYSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDAHIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5P6-1", "uniprot_id": "GMPPB_HUMAN", "id": "Q9Y5P6-1", "name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "aln": "----------MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTG-RIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLQPTSIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBU5-1", "uniprot_id": "GMPPB_DANRE", "id": "Q6DBU5-1", "name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "aln": "----------MKALILVGGYGTRLRPLTLTVPKPLVEFCNKPILLHQVEALVKAGVRHVILAVSYMSELLEREMRAQEQRLGIKISLSHEKEPLGTAGPLALARELLTDNQEPFFVLNSDVICDFPFDDMLKFHQQHGREGTIVVTKVEEPSKYGVVVYEGDSG-RIHRFVEKPQVFVSNKINAGMYIFSPAMLRRIQLRPTSIEKEIFPVMAEEGQLYAMELQGFWMDIGQPKDFLTGMCMYLQSVRQQAPERLRAGPGFLGNVLVDPTAVIGQNCTIGPNVTIGAGVVLEDGVRVKRCTILKGAHIRSHSWLESCIVGWSSSVGQWVRMENVTVLGEDVIVNDELYINGANVLPHKSITDSVPEPRIIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JZB4-1", "uniprot_id": "GMPPB_DROME", "id": "Q7JZB4-1", "name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "aln": "MCGNPAVGNGTRALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKVEAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCNHGKEGTIVVTKVEEPSKYGVVLYD-ENG-CIKNFIEKPQEFVSNKINAGIYIFNPSVLDRIEVKPTSIEKEVFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCLYLSSLRQKQSPKLYTGPGVVGNVLVDPTAKIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRIEGITVLGEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41940-1", "uniprot_id": "MPG1_YEAST", "id": "P41940-1", "name": "Mannose-1-phosphate guanyltransferase", "aln": "----------MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVMVETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYILNPEVIDLIEMKPTSIEKETFPILVEEKQLYSFDLEGFWMDVGQPKDFLSGTVLYLNSLAKRQPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVTIGDGVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEVKDEIYINGGKVLPHKSISDNVPKEAIIM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.****************:.*****:* *:*::***:***. ** .::***.* .: : . :: :. *:.: :* * ********* **. :* .***********::**. : .** ** :*:*:.***:*******:: : . *..*:***: **.*:****:**:.* :: *:::******* ** :.:: :**:::* *****:*******:* ::*.*: :: . :* :*...:**.*:**:* *.. . ***:* :*..*.: *** : *..:* .: ::.** :.* **** . **:* *:*.:****:** *:**:*:**..******* .**: ***", "identical_positions": 179, "similar_positions": 116, "identity": "48.25%" }, { "cls_id": "homologset.agr.SGD:S000002216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1Z0-1", "uniprot_id": "USO1_MOUSE", "id": "Q9Z1Z0-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEE----------------------LEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSRLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKTNNSNQNFFKEGSYIQRMKPWFEVGE---ENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHGDGAQVNGIQPEEISRLREEIEELKSQQALLQGQLAEKDSLIENLKSSQASGMSEQ----------------ASATCPPRDPEQVAELKQELTALKSQLCSQSLEITRLQTENCELLQRAETLAKSVPVEGESEHVSAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSS-----------NSTIAILQTEKDKLDLEVTDSKKEQDDLLVLLADQDQ-------KILSLKSKLKDLGHPVEEED--ESGDQEDDDDEIDDGDKDQDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41542-1", "uniprot_id": "USO1_RAT", "id": "P41542-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEE----------------------VEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSKLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKAWFEVGD---ENPGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENYIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHSDGAQVNGIQPEEISRLREEIEELRSHQVLLQSQLAEKDTVIENLRSSQVSGMSEQ----------------ALATCSPRDAEQVAELKQELSALKSQLCSQSLEITRLQTENSELQQRAETLAKSVPVEGESELVTAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSS-----------NSTIAILQTEKDKLYLEVTDSKKEQDDLLVLLADQDQ-------KILSLKSKLKDLGHPVEEED--ESGDQEDDDDELDDGDRDQDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60763-1", "uniprot_id": "USO1_HUMAN", "id": "O60763-1", "name": "General vesicular transport factor p115", "aln": "MNFLRG----VMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNEEEEE----------------------VEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIISEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGD---ENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRP-----------------AIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGNSVSAG--------------------------------------QLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIG-----NPPVSLLQQCTNILSQ---GSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEE-EQLVQGLCALLLGISIYFNDNSLESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQK------PQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEED----KKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQ----------------SSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSS-----------NSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQ-------KILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3N6-1", "uniprot_id": "USO1_DROME", "id": "Q9W3N6-1", "name": "General vesicular transport factor p115", "aln": "MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQGMPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDE----------------------EADNPT-VSVNVGEQFTEMFIKTPEHVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQRLSPMFELSQDA-EEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHALCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRP-----------------AIVVLLMSMINEKQLLALRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVS-ALSTG--------------------------------------QLLCTGLFSTDALANWFSAVALMHSLVENVALKEELLRVLLATPGG-----QKPITLLEQCTNLMQQE--RYRLQSKVGLLMLLSLWLAHCPGAVKALLETQGTMAYLTAQLCSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESFCSKLAEVSRHEAYSRACKQ------AQIRAKSAGELLLDFEYCKLYKGLEALIAKLVSGFDVDG----IELTELTLSSEAS-ALVSQYKGIIRGMDAQIQALQQSSKELEQENAELKEKLGEEQSLKAQLLDQNTLLKAQLG-------------------------------------------------------ASTGQVQSAQ----------------GAEATPPNE--------EELNAARYQAN-------------------------------------------------MYFAENIRLTKELETLRQQLSAEKQSADAA-----------QDSLAAMQ--------------KDQEDLLELLADQEA-------KLTRYEEAGSTNTLPTSNVA--PSVPAAGGGSPIPSGTASR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25386-1", "uniprot_id": "USO1_YEAST", "id": "P25386-1", "name": "Intracellular protein transport protein USO1", "aln": "MDIIQG-------LIQQPKIQSVDETIPTLCDRVENSTLISDRRSAVLGLKAFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWISQQSRLQNGKYPSPLVMKQEKEQVDQFSLWIADALTQSEDLIHLLVEFWEIDNFHIRLYTIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPHVQKLVAFENIFERLFSIIEEEGGLRGSLVVNDCLSLINNILKYNTSNQTLFLETGNLPKLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGN--TVTTKHQNALLDSSVLMVVLRLAFFHNIPKKVRPVALLTAANMVRSNEHAQLEFSKIDVPYFDPSLPVNSTANGGPIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNNSTNNVGDNAKENGGSNKSDKESDSDKDTDGKDGTEYEGSFKANLFEVLLNYDAELNLNPFKLFFTTDIFMFFFQQDHKYSEELREITRNVTTGNDLEDEEPLKAIQTISELLTTSLTAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDED--VTIKCLVTMLLGVAYEFSSKESP-FPRKEYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSILTPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHDPDEEPINKISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDEEDDEEDEEEGQVA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 128, "similar_positions": 307, "identity": "7.1%" }, { "cls_id": "homologset.agr.SGD:S000002218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWD9-1", "uniprot_id": "TSR1_MOUSE", "id": "Q5SWD9-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "---MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCK-KLKRQLSRIDQRHRASQLRKQKR--------ESVLAEKRQLGSKDGPPHQVLVVPLHSRIS-LPEAFKLLQNEDLGTVYLSERGSTQSFMLLCPSLKHRWFFTYARPG--DLHTLLDMAKVADTILFLLDPLEG----WDSTGDYCLSCLFAQGLPTYTLAVQGLSGFPPKK--QIDARKKLSKMVEKRFP-EDKLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHVADFVP-SEESDLVGTLKISGYVRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVIKSQKKPNMAMEVCVTDAAPDMEEDLKVLMKADPDHQESLQTEAIPDPMEGEQTWPTEEELDEADDLLKQRSRVVKKVPKGTSSYQAEWILDEGDESDGEGGE--------YDDIQHEG----------FMEEESQDGSGEEEEEECETMTLGESVRDDLYDEKVDAEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSFRTSPWDPKE---NLPRDYARIFQFQNFVNTRKRIFKEIEEKEAEGAEVGWYVTLHVSDVPVSVVEYFRQG---APLIAFSLLPYEQKMSVLNMVVSRNPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAA--DKHKFQRFLTADAAFVVTVFAPITFPPASVLLFKQRRNGMH--SLIATGHLFSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVMWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWVKSDISS---TVSEVDME-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEM8-1", "uniprot_id": "D3ZEM8_RAT", "id": "D3ZEM8-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "---MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCK-KLKKQLSRVDQRHRASQLRKQKREAVRSGGWEAVLAEKRQLGSKDGPPHQVLVVPLHNRIC-LPEAFKLLQNEDLGTVYLNERGSTHSFMLLSPSLKHRWSFTYARPG--DLHTLLDMAKVADTILFLLDPLEG----WDSTGDYCLSCLFAQGLPTYMLAVQGLPSLPPKR--QTDARKKLNKTVEKRFP-EDKLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHDADFMP-SEESDLVGTLKISGYIRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVVKSQKKPSMSMEVCVTDAAADMEEGLKVLMKADPDQQETLQTEVIPDPMEGEQTWPTEEELDEANDSLKQRSRVVKKVPKGTSNYQAEWILDEGDESDGEGDES-------DDDIQHEG----------FMEEESQDGSGEEEEEECETMTLGESVRDDLYDEKVDEEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSFRTSPWDPKE---NLPRDYARIFQFQNFVNTRKRIFKEIEEKETEGAEVGWYVTLHVSNVPVSVVESFRQG---APLIAFSLLPYEQKMSVLNMVVSRSPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAA--DKHKFQRFLTADAALVVTVFAPITFPPASVLLFKQRRNGMH--SLIATGHLFSVDPDRMVIKRVVLSGHPFKIFTKTAVVRYMFFSRDDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVLWVKSDISS---TVSEVDME-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2NL82-1", "uniprot_id": "TSR1_HUMAN", "id": "Q2NL82-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "---MAAHRPGPLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSK-KVRKELSRVDQRHRASQLRKQKK--------EAVLAEKRQLGGKDGPPHQVLVVPLHSRIS-LPEAMQLLQDRDTGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPG--DLHVVLDMAKVADTILFLLDPLEG----WDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKK--QIDTRKKLSKAVEKRFP-HDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVP-SEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDEYE------YDDMEHED----------FMEEESQDESSEEEEE-YETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKE---NLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSEVPVSVVECFRQG---TPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAA--DKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMH--SLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISS---TVPQGGME-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VP47-1", "uniprot_id": "TSR1_DROME", "id": "Q9VP47-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "MADHAFHRPGPLKQANKAHKTGRHRSKGAIDNAQKGKIGLRPISH-KHKQQQRKEQRRNQMNQLRKNKR--------EEVLEQKRKLGGQNTAPFLVCLLPMHEQID-PMSALEILKSCDSELVVEN--SPSGIVYINLPRFKQRFAFVTPPVGRGNELIALDYLKVCDTTLLLTTAAFGDDEIFDRWGQRIFNMMSAQGIPTPVVALMDLESINPKR--RPAAKQAAQKVISKLLP-EEKIMQLDTASEALNVMRRIGGQKKRILHNVANRPHLFGDVVEFKPGSDPSDDLGTLEVTGFLRGQSLNVNGLVHIPGLGDFQLSQVVAPPDPYKLD----KSR---------------DGENSEVRLLDRSDPSKRTSLQSENIPDPMDAEQTWPTEDEIAASQAETK-KMKLVKRVPKGYSEYQAAWIPDVEEVEDPDGKDDDDMSEDDDDDKEDDNEDFMSCDNKSFEDEYEKRDSDTEEFQDTVSVASEAAINDEKYDQQMDFQEERETLKKLQQARTDQLWPDEIDTPLDVPARERFQKYRGLESFRTSPWDAKE---NLPADYARIYQFQNFDRTKRRILNEA--KEFEGVLPGLYVTLYVINVPESRWNAFKSAQLMDNIIVYGMLPHEHQMCVMNVVLQRMPDSEVPLKSKEQLIIQCGYRRFVVNPIYSQHTNG--DKHKFERYFRPYETVCATFYAPIQFPPAPVLAFKVNPDSTL--ALVARGRLLSCNPDRIVLKRVVLSGHPMRINRKSASIRYMFFYKEDVEYFKPVKLRTKCGRLGHIKESLGTHGHMKCYFDGQLRSYDTAFMYLYKRVFPKWTYEECLVRTAEHERQHASANRRSSQQVAMEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07381-1", "uniprot_id": "TSR1_YEAST", "id": "Q07381-1", "name": "Ribosome biogenesis protein TSR1", "aln": "---MAGHSHRSSLKNGHKSYKSKHASKGALKRLYKGKVEKEPVGTGKPDKQVSKLQRKNKAKQLRAQRI--------LDSIENRKLFEGKNGAAKIITIVPLVNDLDPLDILYKLLKCADDEGIMVQEVDSKRIFNVHIKKFKSNLKIIIPDMT--NFLNILDCAKVADFVVFGLSGVQEVD---EEFGEQIIRALELQGIASYIGVISNLSAVHEKEKFQLDVKQSLESYFKHFFPSEERVYNLEKNSDALNVLRTLCQRLPRSINWRDNRGYVVADFVDFVETSPDS---GDLVIEGTVRGIGFNANRLVHIPDFGDFQLNKIEKISE--SSQKRKIIKEKATDSLSLELDLQTVFESNMNRDTLDEYAPEGTEDWSDYDEDFEYDG---LTTARYDDHGFLPGREQTSKKAAVPKGTSDYQAKWYLDDVIDANEEEEAEQ-------TNGKDET-----------MMEIDDEMMVEQDNEEVAGDEEYDIEDNEGFEELSPEEEERQLREFRDMEKEDREFPDEIELEPSESAIERLKRYRGLKNLYNCDWQVDEKDPSSPAEWKRLLRIGNYKNTKNRIIKETKNEAQAIAGDRIRMFIRFPKFLLEKIQDPKQL----LFAVYGLLLHEHKNAVVNFSLQRWEQYDKPVPSQEPIVVQYGVRRYTIQPLFSQGSNSPNNVHKYERFLHPDTVSVATCIAPVDFTQSPAIFFKPSPTDAKNIELIGHGTFLNADHSRILAKRAILTGHPFRFHKTVVTVRYMFFRPEDVEWFKSIPLFTKSGRSGFIKESLGTHGYFKATFDGKLSAQDVVAMSLYKRMWPMPSLPWNGM------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . : .: .:* . *: .. **:: . : * :: : ::::: .*** :: : ::: : .:: .. : ::*: . : ::*: * : . . . . : :* . : . : ** **.* :: : *: : : **:.: .: .: .. *. : .:: .. ..: :* .::: *:. .:: ::* : : : : .* ::... .:* * . * * : * :** :*.* *:** . ****:.:: : : . : * . * . :. .* . : **** *.*** * * . : : :.: * .. :: : :: ::: : * . : . : :. :***:: . .* *:::****:.: .. *: .* . * :: *: :: *: .*:. *::* : . : : . .. . : :. : .:.:* :*:: .*:*. : * *: ::* ::.: * **: .*::** : . : ** :*:: . . .* **: *. :..: ** . *:. * ::. : .*:: **.:*:***::: . . :***** :** :**.: * ** ** *.***.*****::*. ***:* : *.. * ****::* : ", "identical_positions": 141, "similar_positions": 262, "identity": "16.43%" }, { "cls_id": "homologset.agr.SGD:S000002219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62273-1", "uniprot_id": "RS29_HUMAN", "id": "P62273-1", "name": "Small ribosomal subunit protein uS14", "aln": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62275-1", "uniprot_id": "RS29_RAT", "id": "P62275-1", "name": "Small ribosomal subunit protein uS14", "aln": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62274-1", "uniprot_id": "RS29_MOUSE", "id": "P62274-1", "name": "Small ribosomal subunit protein uS14", "aln": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VH69-1", "uniprot_id": "RS29_DROME", "id": "Q9VH69-1", "name": "Small ribosomal subunit protein uS14", "aln": "MGFATLWYSHPRKYGQGSRCCRACSNRHGLIRKYGLNICRQCFREYANDIGFKKLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41058-1", "uniprot_id": "RS29B_YEAST", "id": "P41058-1", "name": "Small ribosomal subunit protein uS14B", "aln": "MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFREKANDIGFHKYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. :::****::*:*** **.**.: **:***.**:******: *:**** * ", "identical_positions": 32, "similar_positions": 16, "identity": "57.14%" }, { "cls_id": "homologset.agr.SGD:S000002221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV81-1", "uniprot_id": "D3ZV81_RAT", "id": "D3ZV81-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPVGSCQAEAAATANGTGDEEDDGLAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECSSGLDSNEMSPQEKADKKRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILNTLSEVLGVNAGDTVIQMKEAETQRLKDAAESEDILANANGDGEMEFQDDEMEEIPHKRKLRRKTFISDLLPSTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLMSPLCLSHEIHSALTNCLIPKKVFEKTSSPNSDAVDICSKNPTWKPLIRKMSTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVTTKDPSLVVAGEALDALFDVFADGEEAEKASVQIKLLAALKEFQPVFKMKMRKEGRARYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM4-1", "uniprot_id": "HEAT3_MOUSE", "id": "Q8BQM4-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPIESCQAEAAAASNGTGDEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECLSGLDSNEMSPQEKADK-RNPVESIANEAVNVLWNVCECSGRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVASMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILGALSEVLGMNTGNMVIQMKEAETQRLKTAAESEDILANANGDDLVE--DDEMEEIPHKRKLRRKTFISDLLPPTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFSECSGHLMSPLCLSHEIHSALTNCLIPEKVFEKTSSPNSVAVDICSKNPTWKPLIRKMNTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQILFSQPDFAKHDDFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKDDGTLDTLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEAAEKASVQIKLLAALKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4Q2-1", "uniprot_id": "HEAT3_HUMAN", "id": "Q7Z4Q2-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLG-PLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDDLIE--DDEMEGISHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMCCNEDPSDDEWEELSSSDESDAFMENSFSECGGQLFSPLCLSHEVHTALTNYLIPKKIFEKTAFPNSIAVDLCSRNPTWKPLIRKMNTIQCRALFCLQSLVSLLDVEHLGGAAALQTLAQHLSQLLFSQPDFAKHVDFLEAISSALRALLQTMAS-KNISQCMTPDQLMTLCKAGIHSSNVGVRVNVVSILGITGSVLAKEDGTLETLKNIGCFLLEVTTKDPSLVVAGEALDALFDVFADGKEAERASIQIKLLSALKEFQPVFKMKIRKEGRGNYSTDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI15-1", "uniprot_id": "Q9VI15_DROME", "id": "Q9VI15-1", "name": "SYO1-like TPR repeats domain-containing protein", "aln": "MGKVRKVKTRTP-----SGVDTSAEIDVESAGEAEGCGPIEAICVHLQQANVEEKLNGLHSFAVLALRKEKVPEIRDSELVRIAA-PLLCDKESAIRNAAAGAFRNLSVFG-TEVCDFLVENDILTALLTLVRSYDLTKGGFENELH----------ADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLGFDYRKFGLEVAISVAQLVLVVSENNSSSWNVLASS--TILPELLVAPTESHAQLYLNALAAGILCNVPACAAAHT-----REILNSLDKLLSIDP-QAQLQSCKSEILNAKSKNEAPVLEISMETEDMTETQSANQSKPNQ--------------CDAEVALKNLEHLLDAQRLVAEIITNLGSSDEQSN--WDTDSEHSESESVADYDMEDETADSGS-GGLPANFLETIKQNKVIEKLWQKAQPLQPAVENLVSQQ---ENIKEKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRG---SEDVSVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTLGSLLSEP-----LVKAIVLFLLTYCAQEDDLWALSEGLDALMDIFAVDD-WPQIIAELEMCDRVQALEELFKSKLRQQRRE--LKERRATVQTVKTNFSRFVFYLNKNCKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07395-1", "uniprot_id": "SYO1_YEAST", "id": "Q07395-1", "name": "Synchronized import protein 1", "aln": "MGRSKKRSRASS---SRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNLSSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLRNLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQ---LKPAGKSKIESKRLLFDFADNLLSLVVALSNG--SDDILNEILTESKINEIFQVISQLLKYGVEKLP---INLFNTTLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQAN-----ELTKVLIEGIHCQFLDMKITYDQCNKMIHSVCHSINNIDPVQLVNDINN----------------------------PVEIGPATSKDESSKVITKIKDYNAKRNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTN--FLPHVFMILKDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDD-LSIKIGRMGCIWALLKLIFPDGAFESENRALINVQMLNNSGFARG---------------IIEEFQNNNDLELQQKCINVLSTYAMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGGFLSILKDQVVPNLRQQFKMVDKNK-NPELKERCHDCFTTLDSFIHYKMNENSTNQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :. . . .* :. . : :*. : : . .:: * : . * ** * . : : * :**** :*. : .** *.: : . .. : : . :: .:* :..: . :.: . :* : :: :: : *. . : : :: . . : : * : : .: :: : * : : : : : :.: . . : :. : : :.: :: :: . . :. : .. . . :. :. ::.: . ::: . : .: : .: : * * . . * :. . : : . : : . . *. : . : . : ..: :: : :*. . : .: : : * .: * :.* : . : . : . . :: ::: : : . .: *: * . . ", "identical_positions": 33, "similar_positions": 181, "identity": "4.82%" }, { "cls_id": "homologset.agr.SGD:S000002222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63279-1", "uniprot_id": "UBC9_HUMAN", "id": "P63279-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63281-1", "uniprot_id": "UBC9_RAT", "id": "P63281-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63280-1", "uniprot_id": "UBC9_MOUSE", "id": "P63280-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DDJ0-1", "uniprot_id": "UBC9B_DANRE", "id": "Q9DDJ0-1", "name": "SUMO-conjugating enzyme UBC9-B", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W6H5-1", "uniprot_id": "UBC9A_DANRE", "id": "Q9W6H5-1", "name": "SUMO-conjugating enzyme UBC9-A", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPMKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSPS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KNM2-1", "uniprot_id": "Q7KNM2_DROME", "id": "Q7KNM2-1", "name": "", "aln": "MSGIAITRLGEERKAWRKDHPFGFVARPAKNPDGTLNLMIWECAIPGKKSTPWEGGLYKLRMIFKDDYPTSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEPNIKDPAQAEAYTIYCQNRLEYEKRVRAQARAMAATE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50623-1", "uniprot_id": "UBC9_YEAST", "id": "P50623-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:.: ** :*** ********* * * *:.**:::* **..****:.* * **:: : : : ::**:.*** ** . ::*********:***:*:*::*******:***:**:*:**:.** :.*** *: :.:*: **:*:* **: : ", "identical_positions": 81, "similar_positions": 48, "identity": "50.94%" }, { "cls_id": "homologset.agr.SGD:S000002223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYU1-1", "uniprot_id": "PEX19_RAT", "id": "Q9QYU1-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEGGCGAGVEADRELEELLESALDDFDKAKP------------SPAPSPTISAPDASGPQKRSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQ-----QEFTSCLKETLSGLAKNATDLQNSGMSEEE-------------LTKAMEGLGMD-EGDGEG-NILPIMQS--------LMQNLLSKDVLYPSLKEITEKYPEWLQSH-QESIPPEQFEKYQQQHSVMGKICEQFEAETPTDSEATHRARFEAVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDALNLSGPPGANGEQCLIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40855-1", "uniprot_id": "PEX19_HUMAN", "id": "P40855-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEEGCSVGAEADRELEELLESALDDFDKAKP------------SPAPPSTTTAPDASGPQKRSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQ-----QEFTSCLKETLSGLAKNATDLQNSSMSEEE-------------LTKAMEGLGMD-EGDGEG-NILPIMQS--------IMQNLLSKDVLYPSLKEITEKYPEWLQSH-RESLPPEQFEKYQEQHSVMCKICEQFEAETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDALNLSGPPGASGEQCLIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCI5-1", "uniprot_id": "PEX19_MOUSE", "id": "Q8VCI5-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEEGCGVGVEDDRELEELLESALDDFDKAKP------------SPEHAPTISAPDASGPQKRAPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQ-----QEFTSCLKETLSGLAKNATELQNSGMSEEE-------------LMKAMEGLGMD-EGDGEA-SILPIMQS--------IMQNLLSKDVLYPSLKEITEKYPEWLQSH-QDSTPPEQFEKYQQQHSVMVKICEQFEAETPTDSEATQRARFEAMLDLMQQLQALGHPPKELAGEMPPG-------LNFDLDALNLSGPPGANGEQCLIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IP97-1", "uniprot_id": "Q8IP97_DROME", "id": "Q8IP97-1", "name": "Peroxin-19", "aln": "-------MSEEKKNGDELNDLLDSALQDFDKSGA------------GDQKEPSASSDVATN--AGPEGSEDP--DAFFIEQAKVLADRMNTLFGGP--DTPSGD--IPPLPQDPDQIMAGFKKMAEAAALTLSGENSATDEDVSKYSDSISQALKGLQEGSENLAAP-ASEND-------------IASMFGSLNLEGAGEGDGNMFLPFMEG--------MMQSLLSAEILLPSIRELLEKYPKYLEEN-DAKLSAEDKERYQKQMELYKVIEGHLQSEKTEDSAAVKREKFRVVLDDMRKLQDYGQPPPEILAETGGD-------LPFGDPTAGVAA--GGPGPQCPTM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07418-1", "uniprot_id": "PEX19_YEAST", "id": "Q07418-1", "name": "Peroxisomal membrane protein import receptor PEX19", "aln": "------MNENEYDNFDDLDDLLDEDPTKLDEAEPDDVQAKGSVYNDSENKEKNAESKDSDGVQVANESEEDPELKEMMVDLQNEFANLMKNNGNENNVKTEDFNKLISALEEAAKVPHQQMEQGCSSLKSNSTDKGTVNGSN-PGFKNIVSNTLDRLKENGNKVDTSLAEETKESQRSGQNNNIDDILSQLLDQMVASGGKESAENQFDLKDGEMDDAITKILDQMTSKEVLYEPMKEMRSEFGVWFQENGENEEHKEKIGTYKRQFNIVDEIVNIYELK--DYDELKHKDRVTELLDELEQLGDSPIRSANSPLKHGNEEEELMKMLEIDGNDPNLGNLDKELTDGCKQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*::**:. .:*:: . . . : : . .. . :: . : : : :.. * . : : * : ::: ..: :. : :.. :.::*. * :.. .: . .* . : . : . : *. .. : : :. :::.: * ::* .::*: .:: :::.: . *. *:.* .: * : : . :: :. :** :.:* . : : * :. .:. * ", "identical_positions": 22, "similar_positions": 113, "identity": "6.27%" }, { "cls_id": "homologset.agr.SGD:S000002224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88844-1", "uniprot_id": "IDHC_MOUSE", "id": "O88844-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGT--QKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41562-1", "uniprot_id": "IDHC_RAT", "id": "P41562-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGS--QKVTYLVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75874-1", "uniprot_id": "IDHC_HUMAN", "id": "O75874-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGT--QKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0E0-1", "uniprot_id": "B7Z0E0_DROME", "id": "B7Z0E0-1", "name": "Isocitrate dehydrogenase [NADP]", "aln": "MFALRRTAAMMTSVHRQPHLSQAVFRANFAISAADPKTHKISMDNERMSAVSEHSSVVCSPEQMAQKIKAGPVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLVTGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDG---QVIDEVINDFK-GPGIALGMFNTDDSIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIES-GAMTKDLAICIKGNINAVTRRDYQETFEFINTLAKNLEGALAKNAVAAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21954-1", "uniprot_id": "IDHP_YEAST", "id": "P21954-1", "name": "Isocitrate dehydrogenase [NADP], mitochondrial", "aln": "-----------------------------------------------MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYK-GSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGN----NERSAYVTTEEFLDAVEKRLQKEIKSIE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .**:: *********: **.:**:*:::::*: ***.:*.** *.*::* *.******:.**:********* **:**:*::********************.*: .:****. * ***:*****:.***:*.* ::****.: :.:. .* * : ::: * *:*:.*:* *.** .***:**: *:.: *::******************:::*: :**.::* * *********** :**:***: * ********** ****:****:***:*: *****.*:**********:* **:*:*****.*******:*** :*.:***. * **. **.. ::*:: * ****** . . * * * **:: : :.*: : . ", "identical_positions": 229, "similar_positions": 109, "identity": "47.31%" }, { "cls_id": "homologset.agr.SGD:S000002228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESU6-1", "uniprot_id": "BRD4_MOUSE", "id": "Q9ESU6-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK-LNLPDYYKIIKTPMDMG--TIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGAAKPGVSTVPNTTQAS---TSPQTQTPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP----------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPT----TIDPIHEPPSLAPEPKTAKLGPRRESS-RPVKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALG-LHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSD------------SSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKK--EKDKKEKKK----EKHKKKE--------------EVEENKKSKTKELPPKKTK---KNNSSN-----------------SNVSKKEP--VPTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS--REPSLKNSNPDEIEIDFETLKPSTLR-ELERYVTSCLRKKRKPQAEKVDVIAGSSKMK-------------------------GFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQ----PPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPTR---------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQPQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPG-QQPTHPPPGQQPPPPQPAKPQQVIQH------HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKKQVKGRAEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-IKAPVHLPQRPEMKPVDIGRPVIRPPEQSAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEHFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQQQQRQEQQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGX8-1", "uniprot_id": "D3ZGX8_RAT", "id": "D3ZGX8-1", "name": "", "aln": "MTRGRARSVRDDISALAAAAGLFVLLSRSRGTEAVAAAAAAAAAAAAGGARRQAGPVSAAAQQARRTGPGLAQASRTACGGVRPSVSGEDRCPSRPRGGLPGAPRRGPRNLHCVMEPVRHHLRHRRGAGVGRPQFRGPGACCCSRSAGAARAVGAAAAGWARGLSIGAVAAAAVPLGAGCSRERDRGRGRAGRRDGRPGAGGGRAKLPALPAAAILSSEEEEEEEAAAAGSAVRARPVVPGEECDGITSMSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQSANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK-LNLPDYYKIIKTPMDMG--TIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGTAKPGVSTVPNTTQAS---TSPQTQMPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP----------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPT----TIDPIHEPPSLAPEPKTAKLGPRRESS-RPVKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALG-LHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSD------------SSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKK--EKDKKEKKK----EKHKKKE--------------EMEENKKSKAKELPPKKTK---KNNSSN-----------------SNVSKKEP--APTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS--REPSLKNSNPDEIEIDFETLKPSTLR-ELERYVTSCLRKKRKPQAEKVDVIAGSSKMK-------------------------GFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQQQQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR---------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPTG-QQPTHPPPGQQPPPPQPAKPQQVIQH------HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKK---------------------------------QELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-MKAPVHLPQRPEMKPVDVGRPVIRPPEQSAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEHFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQQRQEQ-QQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60885-1", "uniprot_id": "BRD4_HUMAN", "id": "O60885-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK-LNLPDYYKIIKTPMDMG--TIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNPPP-VQATPHPFPAVTPDLIVQTPVMTVVPPQP----------LQTPPPVPPQPQPPPAPAPQPVQSH----PPIIAATPQPVKTKKGVKRKADTTTPT----TIDPIHEPPSLPPEPKTTKLGQRRESS-RPVKPPKKDVPDSQQHPAPEK---SSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALG-LHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSD------------SSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKK--EKDKKEKKK----EKHKRKE--------------EVEENKKSKAKEPPPKKTK---KNNSSN-----------------SNVSKKEP--APMKSKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS--REPSLKNSNPDEIEIDFETLKPSTLR-ELERYVTSCLRKKRKPQAEKVDVIAGSSKMK-------------------------GFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQP-----PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR---------------------PPAVSPALTQTPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ-LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG-QQPPHPPPGQQPPPPQPAKPQQVIQH------HHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK---------------------------------QELRAASVVQPQPLVVVKEEKIH-SPIIRSEPFSPSLRPEPPKHPES-IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQ--QQQQQQ-------AAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5H6-1", "uniprot_id": "BRD4_DANRE", "id": "F1R5H6-1", "name": "Bromodomain-containing protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDGLDAVQMSGSSSSQGQPSSQAPSSFNPNPPETSNPTRPKRQTNQLQYLLKVVLKSLWKHQFAWPFHAPVDAVK-LNLPDYYKIIKNPMDMG--TIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMPQQEVEISTTAGKGRGRGRRDPDMNMKVGPVLEPLTASPQTRGLSNLTPGPQTRGPPQGPPTLPPQPIVQIQALPPRVPPSLPTIPLHAPQLGPPFSLGPTDCNPPAPIITAVPPPTQTALPPVHIQQSAAPPILQTPISIPNKRKSQKRKADTTTPT----ANDQLNE--SSPAESKSGKTLPRRDNT-RPSKLPKKEAPDSQHHWTAAPGTPSPKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLG-LHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEMLAPAPAPVLHPAPVKTQPVMATASSSDTSSDSSSESE------------SSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQASKPKKK--EKEKKEKKK----DKHKKKAGVMPALEEILEPPPALKPQGKPKNKDPLPKKSKKLSKKEGGK-----------------SNRSMAPPGAAPPTLQPVPGLDTEEDLGLTGGAAMAGMAAGEKCKPMSYEEKRQLSLDINKLPGDKLGRVVHIIQS--REPSLKNSNPDEIEIDFETLKPSTLR-ELERYVSSCLRKKKKPAVPEKSMEAISAVKT-------------------------KGTSSDSGSSSESSSSESEDSETGMASKPKKRGR-GEGKKAHHQTTAPGMPLP------QVPLQPQTPALQPSIQLKQQQ--------------PQHPSPAAYMPPP------VTALEPSQLLENPFDPLAHFMHLPHHANDSSSPAPPHLNAHPPGGPVSPETHPFLNQHPILPSPALHNALPQQPSRPSNRAAPLPPKPLQQSTSQQQPPPQQTLVPPQQLQPQQQQPAPPQQQHLPHHPLHAPQQMRPRPLSPPTLTPQGLLSSQPPQMLLEDDEEPVP---SMSLPMYLQHLQPNRLQATPTSLMQSLQSRPQPPGQPSLLQSVQVQSHLPPPQLPVQTQVQPQQPAPHQPSPQ----LSQHQARHMQQLGFPQGPLQTAQTQPGQHKVSMPSTKAQQIIQQQQAT-QHHSPRQHKADSYNSAHLRDNPSPLMMHSPQIPQYS-LVHQSPSQDKKEPQR------------------------------------------GPSALGGIKEEKLPPSPVMRGEPFSPAMRPESHKHPDSKPTMPGHSQQRADMKPLEMSRPVIRSSEQSGPPPSMQDKEKFKQEPKTPSAPKKVQDVKFKNMGSWASLAQKSSTTPSSGLKSSSDSFEQFRRAAREKEEREKALKAQVEQAEKDRLRKEQEKLRGRDEEDSIEPPRRPLEEPRRRQEPQQVQPPPQQHQTQAQAQTLNPAQSPSASQPTQAPPQSPASSQSALDQQREMARRREQERRRREAMAATIDMNFQSDLMAIFEENLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JJ13-1", "uniprot_id": "BRD2_MOUSE", "id": "Q7JJ13-1", "name": "Bromodomain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQNVTPH-KLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVK-LGLPDYHKIIKQPMDMG--TIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKL-------AALQGSITSAHQVPAV----SSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPL----------------LAVSAAPP----------------------AQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSK---KGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALG-LHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPG-PLPVSTALPPG--LTKSSSESSSEESSSESSSEEEEEEEEDEDEEE-SESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRIG-------------IDEDDKGPRAPRPPQPKKS---KKAGGGGSNATTLSHPGFGTSGGSSNKLPKKSQKTAPPVLPTGYDSEEE---------------EESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQA--REPSLRDSNPEEIEIDFETLKPSTLR-ELERYVLSCLRKKPRKPYT--------------------------------------------------IRKPVGKTKEELALEKK------RELEKRLQDVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQLNSTKKPPKKASEKTESS-AQQVAVS------RLSASSSSSDSSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MGA9-1", "uniprot_id": "BRD2_RAT", "id": "Q6MGA9-1", "name": "Bromodomain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQNVTPH-KLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVK-LGLPDYHKIIKQPMDMG--TIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKL-------AALQGSITSAHQVPAV----SSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPL----------------LAVSAAPP----------------------AQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSK---KGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALG-LHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPG-PLPVSTALPPG--LAKSSSESSSEESSSESSSEEEEEEDEEDEEEE-SESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRIG-------------IDEDDKGPRAPRPLQPKKS---KKAGGGGSNATTLSHPGFGTSAGSSNKLPKKAQKTAPPVLPTGYDSEEE---------------EESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQA--REPSLRDSNPEEIEIDFETLKPSTLR-ELERYVLSCLRKKPRKPYT--------------------------------------------------IRKPVGKTKEELALEKK------RELEKRLQDVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQLNSTKKPPKKASEKTESS-AQQVAVS------RLSASSSSSDSSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25440-1", "uniprot_id": "BRD2_HUMAN", "id": "P25440-1", "name": "Bromodomain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVK-LGLPDYHKIIKQPMDMG--TIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKL-------AALQGSVTSAHQVPAV----SSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPL----------------LAVTAAPP----------------------AQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSK---KGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALG-LHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPG-PLPVSTAMPPG--LAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRAG-------------ADEDDKGPRAPRPPQPKKS---KKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEE---------------EESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQA--REPSLRDSNPEEIEIDFETLKPSTLR-ELERYVLSCLRKKPRKPYT--------------------------------------------------IKKPVGKTKEELALEKK------RELEKRLQDVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQLNSTKKPPKKANEKTESSSAQQVAVS------RLSASSSSSDSSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUX3-1", "uniprot_id": "A0AB32TUX3_DANRE", "id": "A0AB32TUX3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAVTSPAQVPAP-----IVNPPPPEFINSGKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIK-LNLPDYHKVIKNPMDMG--TIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPPPKG---KARKP-------GAPPGSENQQSIALTP----GSPSSSCPSSPPQLAQTPVIAATPVATITT----NVQAAPP-------------------ATAMIPT----------------------AQPVVKK-GVKRKADTTTPTTCAITASRS-ESPTAMLESKHSKVISRRESTGRPIKPPKKDLEDGDVQQPGNK---KSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALE-LHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMPDEPAEPSSPNAVSATAVVS--KSTGSSESSADSSSS---------------------SSDSEEERATRLAELQEQLKAVHEQLAALSQGPVSKPKKKKEKKEKEKKKKDKEKDKDKNKVK-------------AEEDKK-AKSTQPNKQTPQ---KKTSARKPNST------------STTRQAKKGGKPG----AANYESDEE---------------E-SLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQS--REPSLRDSNPDEIEIDFETLKPSTLR-ELERYVKSCLQKKQRKPLPG-------------------------------------------------TGKKSAKSKEELVQEKK------KELEKRLQDVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQLNNNKKPPKKA-EKAGSA--QGGGAS------RLSGSSSSSDSGSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSGSSSESSDSD-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91Y44-1", "uniprot_id": "BRDT_MOUSE", "id": "Q91Y44-1", "name": "Bromodomain testis-specific protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLPSRQ-TAIVNPPPPEYINTKKSGRLTNQLQFLQRVVLKALWKHGFSWPFQQPVDAVK-LKLPDYYTIIKTPMDLN--TIKKRLENKYYEKASECIEDFNTMFSNCYLYNKTGDDIVVMAQALEKLFMQKLSQMPQEEQ---VVGGKERIKKDIQQ---------KIAVSSAKEQIPSK----AAENVFKRQEIPSGLPDISLSPLNMAQEAPPICDSQSLVQITK------------------------------------------------------GVKRRADTTTPTTS--IAKASSESPPTLRETKPVNM-PVKENT------VKNVLPDSQQQHKVLK---TVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDADALG-LHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMARTLQDVFELHFAKIPDEPIESMHACHL----------TTNSAQALSRESSSEASSGDA-------------SSEDSEDERVQHLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAPKRK---------------------------KVNNRDENPRKKPKQMK---QKEK-------------------AKINQPKK-----KKP---LLKSEEE---------------DNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQS--REPSLRNSNPDEIEIDFETLKASTLR-ELEKYVLACLRKRSLKPQAKKVVR----------------------------------------------SKEELHSEKKLELERRLLDVNNQLNCRKRQTKRPAKVEKPPPPPPPPPPPPPPPELASGSRLTDSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSGSGSGSSSSSSGSSSSSSSSGSASSSSDSSSSDSSDSEPEIFPKFTGVKQNDLPPKENIK----------------QIQSSVQDITSAEAPLAQQSTAPCGAPGKHSQQMLGCQVTQHLQAT-ENTASVQTQPLSGDCKRVLLGPPVVHTSAES-LTVLEPECHAPAQKDIKIKN------------------------------------------------------------------------------------------------------------------------------------------------ADSWKSLGKPVKASSVLKSSDELFNQFRKAAIEKEVKARTQEQMRKHLEHNAKDPKVSQENQREPGSGLTLESLSSKVQDKSLEEDQSEQQ--------------------------PPSEAQDVSKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7T3-1", "uniprot_id": "BRDT_RAT", "id": "D4A7T3-1", "name": "Bromodomain testis-specific protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLPSRQ-MAIVNPPPPEYINAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQPVDAAK-LKLPDYYTIIETPMDLS--TIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMPQEEQ---IVGGKERMKKDIQQ---------KTAVSSAKEQTPSK----SAENVFKRQEIPAGFPDVCLSPLNMAQEAPPTCDSQTVVQITK------------------------------------------------------GVKRRADTTTPTTS--SAKASSESPPPLREAKPANA-PVKENT------VKSVLPDSQQQHRVLK---TVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDVDALG-LHNYYDIVKNPMDLGTIKGKMDKQEYKDACEFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFEMHFAKIPDEPVESMRACHL----------TTNSAKALSRESSSEASSGDC-------------SSEDSEDERVQRLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAPKRK---------------------------KVN-RDENPKKKAKQMK---QKEK-------------------AKSNQPKK-----KKP---LLKLEEE---------------DNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQS--REPSLRNSNPDEIEIDFETLKASTLR-ELEKYVLACLRKRSLKPHAKKVVR----------------------------------------------SKEELHSEKKLELERRLLDVNNQLNCRKRQTKRPAKVAVSPRPPLPPPPPPPP-ELASGSRLSDSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSS-----SSSGSGSSSSSSSSSGSGSSSSDSSSSDSSDSEPEISPKFTGVKQNDLPSKENTK----------------QIQCSVPDITSAETALVQQSTGPCGAPGKPPQQMPGCQVPHHLQAT-ESTASVQTQPLAGDCKRVLHGPPVVHASAES-HTVLELQCHAPVQKDIKIKN------------------------------------------------------------------------------------------------------------------------------------------------ADSWKSLGKPVKASSVLKSSDELFNQFRKAAIEKEVKARTQEQIRKHLEHSAKDPKVSQESQREFGSGFTPESSSNKVQGRSHGEEQSEQQQLP-----------------------SPSETQDISKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58F21-1", "uniprot_id": "BRDT_HUMAN", "id": "Q58F21-1", "name": "Bromodomain testis-specific protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK-LQLPDYYTIIKNPMDLN--TIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ---VVGVKERIKKGTQQ---------NIAVSSAKEKSSPS----ATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTK------------------------------------------------------GVKRKADTTTPATS--AVKASSEFSPTFTEKSVALP-PIKENM------PKNVLPDSQQQYNVVK---TVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALG-LHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYI----------KTDITETTGRENTNEASSEGN-------------SSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKE---------------------------KVNNSNENPRKMCEQMR---LKEK-------------------SKRNQPKK-----RKQQFIGLKSEDE---------------DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQS--REPSLSNSNPDEIEIDFETLKASTLR-ELEKYVSACLRKRPLKPPAKKIMM----------------------------------------------SKEELHSQKKQELEKRLLDVNNQLNSRKRQTK--------------SDKTQPSKAVENVSRLSESS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSS----------------SSSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQLAFNYQELEHLQTV-KNISPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESECQAPVQKDIKIKN------------------------------------------------------------------------------------------------------------------------------------------------ADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQ--------------------------QSSEAQDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IS77-1", "uniprot_id": "I3IS77_DANRE", "id": "I3IS77-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDVKPPQHFTMNGNPPPPEFKNPKKPGRLTNHLQYIEKVVIRALWKHHFSWPFRQPVDAVR-LNLPDYYTIIKNPMDLT--TIRKRLENNYYWKAMECVEDFNTMFTNCYVYNRPGDDIVLMAQVLEKLFLEKVAEMPEEEYEISALTTKGPVKGARKS-------------TIGLKKRPPS-----PMSEVVFQQTVTVIPPDALHTIPSAPLSAQLTAKLKN-----------------------------------------------------------GVKRKADTTTPSAS---SIPSCESSSCVTEPKVLKLFSRRGSG-RPIKPPCKDLPESPPQHQVGR---RTKLSERLKYCNAILKEMFSKKHSAYAWPFYKPVDAETLG-LLDYHEIIHQPMDMSTIKKKMEAREYTDALQFAADMRLMFSNCYKYNPPGHEVVSMARKLQDVFEFRFSKIPDEPKNANPVSSHNRVKKER-ARSPSSSESSDSESSSPENSSDT--------------EEEDEEERAHRLASLEEQLKAVREQLQLLTQTPLLKPKKKEKSKKKKKKER--------------------------ESSKRKGEEMKKPAKILK---RSSSSK-----------------SSGRKESR-----------ACDSEEE---------------MNTLPMSYEEKRQLSLDINKLPGDKLGKVVNIIKA--REPLLRDTDPEEIEIDFETLKPSTLR-ALECYVVGCLRKKTKETNKNKPPKKSKIKEKDKDLQHATGEQNSHKKTKIETDGEIKDTTHPSRLSDSSSSSSSSDSSSSDSSSSDSCDSDSEQKTKRKQSKGPGHANKIKKKALRQANAEVKDSSSASGVMCQSR-------------------------------------------------------------------PSSLVSETGSKDLFASQHAKHPVEDITAITALHSRLPPQPSRPSGKAAALPR-----------------------------------------------------------------------------------KIWTTPSPLSLPPDQALSPLYNASATSPCKDHTIIPAKSSPESVTPDPPNSLPKDPLFPCSPLLPPPDMQVSQVGPPSSVAAKIPPQKSEKEGIPPLLSPLTSPSAAMPATGSQSTSSSQFEQCRLLSPLHESPLASMRNEQDCPETPEESSVHLHKIHGAKHDDNELCKSIQDAKSNLPK----------------------------------------------------------------------------------------------------------------------------------------KDIVLKHADSWTSLGKLATQTPCTIKSSKESFQQFRKVAMEKEERERARKLQLEAGREKSSTDKSCLTQQPQKAKLECQPSKPEVESAELPLMAAILDTP-------------------------KAPEPSSVLQNSVDREREMARKREQERRRREAMSGVIDMTMQRDIMATFEKNLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1S2-1", "uniprot_id": "Q9W1S2_DROME", "id": "Q9W1S2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKQETERSSP---------EINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLG-LHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQ-----------------------LYICSSGSKVRAEEESSSDE--------------SDSSSPEDEVNGSEVSPSIMGAPPSCTPTTECTPTPDWTPPATLETSEQQE-------------------------------------------------------------------------------------------------------------------PFTTEEDLDLHAKIQQLDGEVLLHVIHFIQR--MEG--AEYCNKELEFDICKLKVHTKR-GIRDYLASKGFTG----------------------------------------------------------KRVARTKPKYN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07442-1", "uniprot_id": "BDF2_YEAST", "id": "Q07442-1", "name": "Bromodomain-containing factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNNINVGVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSPISISNASTPESFPEHPLGLERETEPALEAEMEAEELPPHQSKYLLSSIKATKRLKDARPFLKPVDPIALNIPHYFNYVQTPMDLS---LIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKLSAMPPRVLPASALK----------------------------------------------------KTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPKS----KTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALN-LPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLENQDILNEIETDSDLE---------EDNYSSSYSSDDEYDDEDINE---------------NDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKERKRKHLGKTLLRRK----------------------------------------------------------------------------------------------------------------AMKHSVDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDILDEATIARIYERYFEKKNNNNSKRKLSGN-----------------------------------------------YSTAPTNKKKKTLKFLEKDEIINNNNYSDSEEDSSDSSDSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VCG6-1", "uniprot_id": "Q9VCG6_DROME", "id": "Q9VCG6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNELQSNSNQPPPRNEPYLQPVNGIVQPPVIPPPNRPGRRTNILEELKS-VLNCLWRNRFSYHFRHPVDSVS-LGVPDYHAVVKHPMDLS--TIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAFYMRMESIDLSTEVELKPKSEKRKRKATES-------LDQASTSFSAPRASNNYSRQWLSSSSSWLCPPPMPGGVSSFNPSFRNFVGPSLIPSFMPDSLVN------------------------------------PMQSMHPMSSMMNPIFKNNWETNEAMDPPPSEPISYRPLDSLAAPLPSPPMEPMTLPWPTPAPVESPASSPPPAPNPPIIICYK-SLDRMIEKSHSDHLLKSMVKRKRKQVTWAFNQADYWRRYSQNPDYDHDREEKLDWKILQERLDSDNFESFDGFVSSVRKMFQNALRCFPEDGLVKVSVKKTNEIFEKRLPKYR---------------------------------------------------------------ELIATAKEKGRQLVASREQDFRDSQNLLIKQENANKNFKGWVPKP------------------------------------------------------------------------------------------------------------------------------FIIKTESLFVQEQRVYKMEP----QDVQEFSPGTEPLDDQTYDSD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::* :. . : * :. :* . .. :* : .: : * .:. :* * . : : :*: : . .: . . . *: : :: :* . ", "identical_positions": 10, "similar_positions": 41, "identity": "0.54%" }, { "cls_id": "homologset.agr.SGD:S000002230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZX74-1", "uniprot_id": "A0A8I5ZX74_RAT", "id": "A0A8I5ZX74-1", "name": "B-cell receptor-associated protein", "aln": "MSLQWTAVATFLYAEVFAVLLLCIPFISPKRWQKIFKSRLVELVVT-YGNTFFVVLIVILVLLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFR----AQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGTAEDGGKLDVGSPEMKLEE-NKILKTDLKKLKDELASTKKKLEKAENEALAMQKQSEGLTKEYDRLLEEHAKLQASVRGPSDKKEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61335-1", "uniprot_id": "BAP31_MOUSE", "id": "Q61335-1", "name": "B-cell receptor-associated protein 31", "aln": "MSLQWTTVATFLYAEVFAVLLLCIPFISPKRWQKVFKSRLVELVVT-YGNTFFVVLIVILVLLVIDAVREILKYDDV-TEKVNLQNNPGAMEHFHMKLFR----AQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAEDGDKLDIGNTEMKLEE-NKSLKNDLRKLKDELASTKKKLEKAENEALAMQKQSEGLTKEYDRLLEEHAKLQASVRGPSVKKEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51572-1", "uniprot_id": "BAP31_HUMAN", "id": "P51572-1", "name": "B-cell receptor-associated protein 31", "aln": "MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVS-YGNTFFVVLIVILVLLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFR----AQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61334-1", "uniprot_id": "BAP29_MOUSE", "id": "Q61334-1", "name": "B-cell receptor-associated protein 29", "aln": "MTIQWAAVASFLYAEIGLILLFCLPFIPPQRWQKIFSFSVWGKIAS-FWNKAFLTIIILLIILFLDAVREVRKYSSTNVVEKNSAIRPSAFEHTQMKLFR----SQRNLYISGFSLFFWLVLRRLVTLITQLAKEIANKGVLKIQAENTNKAAKKFMEENEKLKLGLRN------DNAEEHLLEAENKKLIESKENLKTELKKASDALLKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKKGL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F288-1", "uniprot_id": "F7F288_RAT", "id": "F7F288-1", "name": "B-cell receptor-associated protein", "aln": "MTIQWAAVASFLYAEIGLILIFCLPFISPQRWHKIFSFSVWTKIAS-FWNKAFLTIIILLVVLFLDAVREVKKYSSINVVEKNSASRPAAYEQAQMRLFR----SQRNLYISGFSLFFWLVLRRLVTLITQLAKEITNKGVLKIQAENTNKAAKKFMEENERLKLVLKNN-----DNTEEHVLETENKKLVEDKERLKTELKKASDALFKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKENKKGL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHQ4-1", "uniprot_id": "BAP29_HUMAN", "id": "Q9UHQ4-1", "name": "B-cell receptor-associated protein 29", "aln": "MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIAT-FWNKAFLTIIILLIVLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFR----SQRNLYISGFSLFFWLVLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH-----GKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0M4-1", "uniprot_id": "Q9W0M4_DROME", "id": "Q9W0M4-1", "name": "Endoplasmic reticulum transmembrane protein", "aln": "MSLVWTLIAGFLYAEIALVLLLVLPVLTPYRWNRFFKSKFLSMLGQ-QAHIYFLLIMGILVIFLLEAIREMRKYSGL---QQSNEVHLNVEMQHSMKLFR----AQRNFYISGFAIFLALVIRRLVNLICTQANLMAQSEASFKQAQSATAAARSLLENK-----------------NTEKAKEAGEDTTLIELNKLRERVQELTSDLNREKKDKEAVKSQAESINREYDRLTEEYSKLQKKITIGGGGNKDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07451-1", "uniprot_id": "YET3_YEAST", "id": "Q07451-1", "name": "Endoplasmic reticulum transmembrane protein 3", "aln": "MSLYYTLVFAILVVEIFMFSILALPIPS--RYRRPLTLLLLKPFKSSTVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFFAQRNMYLTGITLFLTFVVVRTFGLV---IELLTMKDIYRASPPVASSDVKK------------------------------------NDSVTAEAAAQSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :: : :* .*: . :: :*. . *:.: :. . . : : :: :::::.::.:..: . . . . : :.:: :***:*::*::::: ::: * . *: :: . .. :. .:. . . . . : .:. : : : : * :* :: .** : ", "identical_positions": 16, "similar_positions": 88, "identity": "6.32%" }, { "cls_id": "homologset.agr.SGD:S000002232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYQ9-1", "uniprot_id": "D3ZYQ9_RAT", "id": "D3ZYQ9-1", "name": "E3 ubiquitin protein ligase", "aln": "------MSGIG--NKRAAGEPGTS-VPPEKKTAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDL--DQG---------LGDLLTERKALVVPEPEP-----------------------DSDSNQERKDDRE----------------------------RGEGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNS-GDNLIMEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQ---------SQSSTE-DAKDE-------------PTELKQDSEDLATHSSALKASQE--DEVKSKRDEEERERERREKERERERE---REKE-KEREREKQKLKESE---KERDPVKDKDKGKHDD----------GRKKEAEIIKQLKTELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAVAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKP------DNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTM8-1", "uniprot_id": "BRE1A_MOUSE", "id": "Q5DTM8-1", "name": "E3 ubiquitin-protein ligase BRE1A", "aln": "------MSGIG--NKRAAGEPGTS-MPPEKKTAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDL--DQG---------LGDLLTERKALVVPEPEP-----------------------DSDSNQERKDDRE----------------------------RGDGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNS-GDNLIVEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQ---------SQSSTE-DPKDE-------------PTELKQDSEDLATHSSALKASQE--DEVKSKRDEEERERERREKERERERE---REKE-KEREREKQKLKESE---KERDSVKDKEKGKHDD----------GRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKP------DNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTR2-1", "uniprot_id": "BRE1A_HUMAN", "id": "Q5VTR2-1", "name": "E3 ubiquitin-protein ligase BRE1A", "aln": "------MSGIG--NKRAAGEPGTS-MPPEKKAAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQTKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDL--EQG---------LGDLLTERKALVVPEPEP-----------------------DSDSNQERKDDRE----------------------------RGEGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNS-GDNLIVEEAVQELNSFLAQENMRLQELTDLLQEKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQ---------SQSSTE-DPKDE-------------PAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERE---REKE-KEREREKQKLKESE---KERDSAKDKEKGKHDD----------GRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQEDISRLRRKLETTKKP------DNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R926-1", "uniprot_id": "F1R926_DANRE", "id": "F1R926-1", "name": "E3 ubiquitin protein ligase", "aln": "------MSGQK--RPSDAGSSATLGAPPEKKKGGEDGEGMSTGSGGSTAVETVIKLGGGANLEEQDIKALQIKNRKLGEALDQRQVIEDELRERVETLETRQATDDASLLILNRYWNQFDEHVRLFIRRCDQ--SGSEP-------VESQPPEGRSLKPGTPEP-----------------------DGDSNQERAKD------------------------------RGQQGEGVSSFLATLASSTSEEIDAELQERVESSCKQASRVVEIYENLKNMVDQLKKDLES-GKDGGLWDVAVRLNALLTGMNERLCQLTDGLQQKHSHMTSESRSLGRAANRADNRISELQGLIEELQWDMEKIRRRENRLNTHLVEVLERVNSKGYKVCG------------EASSVCG-TITINKRKFEEMNSELEENRELAENRLSELQKLQQDLQTVYQENTNMKVELLSRAEEVARDSAEYRCLQSQFSVLYNESLVLKSQLDETKARLNTTRTARLRQLDHMENDEVSLQRKVRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISTLQTHNQQMKGEVVKYKLRLREAQQELNQLRAAKGNAAVQ---------SQSSTEMDVKEETVSPLTPAPTTDVTVKTEPDSGSATPSTTGITVKTEPGTDAETVVKEEEKEKEK-DKEKEKEKD---KEKEQRERERVTRGSTGSLGVKEERDKAGTSSSQSEDIPVERCAVIGGPKRKEMEQLKIVRVELKKAQESQREMKLLLDMYRSAPKEQRDKVQLMAAEKKTKSEAEELRQRVRELEERERREGKKMADEEALRKIRSVEEQIDILNKKLSLAK-----------------------QEEDALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQLLTLKTQVDAQLQVVRKLEEKERLLQGTISAAERELGLRT-------QALEMNKRKAQDSVLLSEEVRTQLEGVQQRLRSVREEVIENSISREKESFNARRAQEDISKLRRKIEKAKKPA-----ENIRNGDEILNEEINEYKARLTCPCCNSRVKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3U319-1", "uniprot_id": "BRE1B_MOUSE", "id": "Q3U319-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "------MSGLS--NKRAAGDGGSG--PPEKKMNREE-------KTTTTLIEP-IRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSS-----GTEVPGCQEGLTRDVIPRPDP----------------------GTSDLREPLPVQFR-----------------------------APLSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARVRTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNS-GYYVSG------------SSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCIPTLSHPDDPGLNALAPGKEDS----GPGPGGTPDCKKEMALLAGATSATSSIKKEELVSSEDDAQALTPVTQGLPSRGREPEAR---PKRELREREGPSLGPPPAA----STLSRADREKAKVEE----------AKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRS-------QALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKV------EVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CJB9-1", "uniprot_id": "BRE1B_RAT", "id": "Q8CJB9-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "------MSGLS--NKRAAGDGGSG--PPEKKLNREE-------KTTTTLIEP-IRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSSS----GTEVPGCQEGLTRDVIPRTDP----------------------GTSDLREPLPMQFR-----------------------------APLSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARARTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNS-GYYVSG------------SSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCGPNLSHPDDSGLNALAPGKEDS----GPGPGGTPDSKKELALVAGATSVASSVKKEELVSSEDDAQALAPGTQGLPSRGREPEAR---PKRELREREGPSLGPPPAA----STLSRADREKAKAEE----------ARRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRDLEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRS-------QALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKV------EVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75150-1", "uniprot_id": "BRE1B_HUMAN", "id": "O75150-1", "name": "E3 ubiquitin-protein ligase BRE1B", "aln": "------MSGPG--NKRAAGDGGSG--PPEKKLSREE-------KTTTTLIEP-IRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS-----APEAPGTQEGPTCDGTPLPEP----------------------GTSELRDPLLMQLR-----------------------------PPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNS-GYYVSG------------SSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEG----GPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPSSRGREPEAR---PKRELREREGPSLGPPPVA----SALSRADREKAKVEE----------TKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRS-------QALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKV------EVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U5A5-1", "uniprot_id": "A0AB32U5A5_DANRE", "id": "A0AB32U5A5-1", "name": "E3 ubiquitin protein ligase", "aln": "MSKKGSMSGAGGGKRPSGGDSPPG--PPEKKLKKEE-------KTTTTLIEP-IRIGGVSSTEEMDMKVIQFKNKKLCERLEQRQALEDELREKIEKLEKRQATDDTTLLIVNRCWTQLEENIHELLQHVEPKDAPAPVQIPATPPVPADAPVPAVAPSPAPEPSAPLPAPVEGEDGLPQPSVAAEGTEDQQQPSQEKEQQQEQQQQPDSVEKSAEAPVADEIPAPSPLPPLSESAKAFLAILDNSSEEELTLQLQDRMQFSKGAVACMVCIFDRLHTSIDKLCTRVESAACEDDSQRDIATTNRKLLEENNRLYDLASSLQGKHHKMSLEYNELVDKVTSSETKVSEMETAVEDLQWDIEKLRKREQKLNKHLAEALEQLNT-GYHATG------------SSGGLPGGQITLSIQKFESLNAELEQNQELANSRMAELEKLQQELQEAVREGEKLKMDLRNIPEEVLKETPEYKCLQSQFSLLYNESLSVKTQLDEARALLLTAKNAHLRQIEHMESDELSLQKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDVQRYKRKLRETQMEINKLKCQS----------------GEATALILEESV----GDG--------------------GLEVKKEEDDDQEEEEERRRELER-QRAREREREAE---RERE-RERE---------------------RERQRSEE----------LKRKDSDTLKMLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAEKKSKAEVEELRQRVRELEEREKKESKKLADEDALRKIRVAEETIEHLQKKLAATK-----------------------QEEEALLSEMDVTGQAFEDMQEQNSRLMQQLREKDDANFKLMSERIKSNQIYKLLREEKEELADQVLTFKTQVDAQLLVVQKLEEKEGVLQSTLATLEKELALRT-------QALELNKRKAVEAAQLAEDLKVQLEHTQTKLREIQASVLDNRTARERESVNLKKAQEDLSRLRRKLEKQKKV------EVYTDADEILQEEINQYKAKLRCPCCNTRDKETVLTKCFHVFCYECLKTRYDTRQRKCPKCNAAFGANDFHRIYIT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRP9-1", "uniprot_id": "BRE1_DROME", "id": "Q9VRP9-1", "name": "E3 ubiquitin-protein ligase Bre1", "aln": "------MSKRS--ADDATGSSCLVAAAAAGQPPIKK-----------VHFEP-HLIGPVSTLEEMDIKVLEFQNKKLAQRIEQRMRTEAELRHRIEQLEKRQTQDDAVLNVVNRYWNQLNEDIRVLLQRFDAETADELE-------NRNENEVTTSFLAQLSTWD----------------------KEELDEKLANRVQ----------------------------VSKRAVAKIVQVIDRLMQRNEKITHVLKGDSLASAGSGSGAGAGGEEEQQQASGDAETTTSSAGVHALEETLKQTHIEIMSENHKLQNLNTSLHEKFHTMSLKMKEYQDAHTAKETENAELKNQIDELQYDLEKIHCRNDKLENHLAEAIEKLKA-YHQIYGDPNKSTNSAKTPTTTGSGGATTSVNSQLLEELQKELEEYRELANNRLQELDKLHATHRETLKEVEKLKMDIRQLPESVIVETTEYKCLQSQFSVLYNESMQIKTMLDETRNQLQTSKNQHLRQIEVMESEELIAQKKVRSEMIQMEDV-LALIRKEYETLRIEFEQNMAANEQTAPINREMRHLITSLQNHNGQLKGEVQRYKRKYKDTSTDNLKLRQELADALATLEGNKLQAATGAAGEEIKQENSTG-VKEENSNNVSASGQTNQTNSGNDTNVAIKEENHISAEDEADDEASGKDVKDGIKQEKLSSGDAAAAEKKDSPGPGNSTSSATNSVPVKNEKDSKDGVKGKD----------VKAVESETVRDLKAQLKKALNDQKEMKLLLDMYKGVSKDQRDKVQLMATEKKLRSEIEELRQQLKKLQESKREERKKLADEEALRKIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQEQNSRLIQQLREKDDANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKERSLQATVASIEKELMLRQ-------QAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEAEAYKTKRLQEELAQFKRKAERMKKME-----MSGTTIDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYLQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07457-1", "uniprot_id": "BRE1_YEAST", "id": "Q07457-1", "name": "E3 ubiquitin-protein ligase BRE1", "aln": "------------------------------------------------------------MTAEPATKKIKLELSDPSEPLTQSDVIAFQKEALFRCINRR------------------RVDFEALRKQYELS--------------------------------------------------------------------------------------------------------------------------RRECIDVSRKLANIMALIVTLARFIETFCTDANE---KQLCREIAQGDETLIVQRSDSFMKLLTKYGKPNTTDSNTNSNASDHIQELTTELKNLRKSKEELFYENSQLTEEISALKEYYTNIIRKYDR---------------------DESFTIKRVFKEDKTDAVKELREDEKESNENNIKSGNKDSSAINGDNTSKKSEKGDELVQAEDERKEDAE------------NEKLELDLKFSDLRAEIN-SLSSTIKDLENIRRENEEELIKTRSEVSNLKKQQIAAADQDPDFKSYDHESLLAKIQHLTEQNAELSEINSSFLSKFQVLAKEKEIYTKKVREEFQKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------LDSLVEMNSSLEKDVVRIRTARDDLLSKIAILEAEKSKTEVLSDLQHAIDILKEQWTKIDQRSNDTKSS--------------------------------------------STQDALIKEIQDLEKGFRELSDLTHKKYSEIINHESVISKLTVEKTKADQKYFAAMRSKDSILIEIKTLSKSLSKSNELILQLKDSDRLLQQKIGNLHKQLDLSQNNERRLIDSSKTETLKIIDLNNTSTKLKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHFKQKASHLESKCEKLHDTLFRGNNKNKGSSDEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMRKCPTCNKAFSSNDLLTVHL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: : . : : * : . .. :: * .. : : : : : . . : . : .* : . .. :. ::* :: .:: . . *: : .: :.: . .. : :: *: :* :.. . :* . * *. : * **.: :. :.: : : : :.:: :. :: * *:*: :::. :* :: : :.*. :* :: * *: .: ::: .: : : *. : :: . *.. : : .:: : : . .: .*: :: :*:. .:*: : *:: . :: * .: ::**:.*:: :.*.::.: . : .:: :::.. ** *: *::* : ..* : :: ...:. : :*::.: ** .:. .::* * :: : .. * : : .:: ** : . .. : . : : :: ::. :::. * * :. ** : **: ::: : *. *. . *: .:..* **** :* : * :* ****.** **.::* ::: ", "identical_positions": 73, "similar_positions": 245, "identity": "6.37%" }, { "cls_id": "homologset.agr.SGD:S000002233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62900-1", "uniprot_id": "RL31_MOUSE", "id": "P62900-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62902-1", "uniprot_id": "RL31_RAT", "id": "P62902-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62899-1", "uniprot_id": "RL31_HUMAN", "id": "P62899-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LCC6-1", "uniprot_id": "A0ABK0LCC6_RAT", "id": "A0ABK0LCC6-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKK-GRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYCIRVHLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0KXX7-1", "uniprot_id": "A0ABK0KXX7_RAT", "id": "A0ABK0KXX7-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGKKK-GRSAINEVVTREYTINIHKRIHGVGFKKRAPWALKEIRKFAMKELGTPDVRTDTRLNKAIWAKGIRNVPYRIRVCLSRKHNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LTP6-1", "uniprot_id": "A0ABK0LTP6_RAT", "id": "A0ABK0LTP6-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKK-GRSAINKVVTREYTINIHKRIHGVGFKKRAPRALKEIQKFAMKEMGTPDVHIDTRLNKAVWDRGIRNVPYRIRVRLSGKRNEHEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V597-1", "uniprot_id": "RL31_DROME", "id": "Q9V597-1", "name": "Large ribosomal subunit protein eL31", "aln": "MTKTK--GEKI-NKSAINEVVTRECTIHLAKRVHNIGFKKRAPRAIKEIRKFAEREMGTTDVRIDTRLNKHIWSKGIRSTPFRIRVRLARRRNDDEDSPNKLYTYVTYVPVSTFKNLQTENVESSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C2H8-1", "uniprot_id": "RL31A_YEAST", "id": "P0C2H8-1", "name": "Large ribosomal subunit protein eL31A", "aln": "-------------MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHMGTDDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAKGLQTVVVEEDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::.***** **:: **:*.:.****** *:***:*** .:** **: ..**: :* :*::.. : :*: :: ::*:.**: * *:: * * *:: *.*** *:.. ", "identical_positions": 45, "similar_positions": 43, "identity": "35.43%" }, { "cls_id": "homologset.agr.SGD:S000002235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT04-1", "uniprot_id": "E9PT04_RAT", "id": "E9PT04-1", "name": "", "aln": "-----------------------------------------------------------------MTLLSRCRSWRSFH-------CRLTAWLP-GEWLLVGTKQGHLLLYRIRKDVG-----------CNRFEVTLEKSNKNFSKK-IQQIHVVSQFKILVSLLENNIYVHDLL----TFQQITTVSKAKGASLFTCDLQH-TETGE----EVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRD----------YYLIRVDAKGSIK-ELFPTGKQL-----EPLVAPLADGKVAVGQDDLTVVLNEEGICTQKC-----------------------ALNWTDI-PVAMEHQP------------------PYIVAVLPRYVEIRTLEPR-LLVQSI-----ELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDD-----------------SDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYR--KQLQYPN-PLPTLSGAELEKAHLA--LIDYLTQKRSQLVKKLN--------------DSDHQSSTSPLMEGTPTIKSKQKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHE-----------RTVQYLQHLG-TENLHLIFSYSIWVLRDFPEDGLKIFTEDLPEVESLPRD----RVLNFLIENFKALAIPYLEHIIHVWEETGTRFHNCLIQLYCEKVQNLMKDYLLSLPTGKSPVPAGEEAGELGESRQKLLTFLEISSSYDPGRLICDFPF-DGLLEERALLLGRMGKHEQALFIYVHVLKDTKMAKEYCHK-HYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIG------NSAFARYPNGVVVHYFCSKE---------------------------VNSADT------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5L3-1", "uniprot_id": "VPS39_MOUSE", "id": "Q8R5L3-1", "name": "Vam6/Vps39-like protein", "aln": "----------------------------------------------------------------MHDAFEPVPILEKLP-------LQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVPADVASPESGSCNRFEVTLEKSNKNFSKK-IQQIHVVSQFKILVSLLENNIYVHDLL----TFQQITTVSKAKGASLFTCDLQH-TETGE----EVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRD----------YYLIRVDGKGSIK-ELFPTGKQL-----EPLVAPLADGKVAVGQDDLTVVLNEEGICTQKC-----------------------ALNWTDI-PVAMEHQP------------------PYIVAVLPRYVEIRTLEPR-LLVQSI-----ELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDD-----------------SDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYR--KQLQYPN-PLPTLSGAELEKAHLA--LIDYLTQKRSQLVKKLN--------------DSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHE-----------RTVQYLQHLG-TENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRD----RVLNFLIENFKALAIPYLEHIIHVWEETGSQFHNCLIQLYCEKVQSLMKDYLLSLPTGKSPVPAGEEGGELGEYRQKLLMFLEISSHYDPGRLICDFPF-DGLLEERALLLGRMGKHEQALFIYVHVLKDTKMAKEYCHK-HYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIG------NSAFARYPNGVVVHYFCSKE---------------------------VNSADT------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JC1-1", "uniprot_id": "VPS39_HUMAN", "id": "Q96JC1-1", "name": "Vam6/Vps39-like protein", "aln": "----------------------------------------------------------------MHDAFEPVPILEKLP-------LQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVPADVASPESGSCNRFEVTLEKSNKNFSKK-IQQIHVVSQFKILVSLLENNIYVHDLL----TFQQITTVSKAKGASLFTCDLQH-TETGE----EVLRMCVAVKKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRD----------YYLIRVDGKGSIK-ELFPTGKQL-----EPLVAPLADGKVAVGQDDLTVVLNEEGICTQKC-----------------------ALNWTDI-PVAMEHQP------------------PYIIAVLPRYVEIRTFEPR-LLVQSI-----ELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDD-----------------SDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYR--KQLQYPN-PLPVLSGAELEKAHLA--LIDYLTQKRSQLVKKLN--------------DSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHE-----------RTVQYLQHLG-TENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRD----RVLGFLIENFKGLAIPYLEHIIHVWEETGSRFHNCLIQLYCEKVQGLMKEYLLSFPAGKTPVPAGEEEGELGEYRQKLLMFLEISSYYDPGRLICDFPF-DGLLEERALLLGRMGKHEQALFIYVHILKDTRMAEEYCHK-HYDRNKDGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPKANLQAALQVLELHHSKLDTTKALNLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIG------NSAFARYPNGVVVHYFCSKE---------------------------VNPADT------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1YZ39-1", "uniprot_id": "A0A8N1YZ39_DANRE", "id": "A0A8N1YZ39-1", "name": "", "aln": "----------------------------------------------------------------MHDAYEPVPILEKLP-------LQIDCLAAWDDWLLVGTKPGHLLQYRIKKDAG-----------TNRFEVTLEKSNKNFSKK-IQQLFVVSQYKILVSLLENNIHVHDLL----TFQQITVVSKAKGATLFACDLQQ-SESGE----AKLRMCVAVKRKIQLYYWKDREFHELQGDVTAPDIPKSMAWCENSICVGFKRD----------YYLIRMDGRGSIK-ELFPTGKQL-----EPLVAPLADGKAAVGQDDLTVVLNEEGVCTQKC-----------------------ALNWTDI-PVAMEHQP------------------PYIIAVLPRYVEIRTVEPR-LLVQSV-----ELQRPRFITSAGSNVVYVASNHFVWRLVPVSIASQIRQLLQDKQFELALQLAKMKDD-----------------FDTDKRQQIHHIQNLFAFNLFCQKRFDDSMQGFAKLGTDPTHVIGLYPDLLPSDYR--KQLHYPN-PLPPLSGAELEKAHLA--LIDYLTQKRSHLVKQLN--------------DSD-PSTTSPLMEGTPTIKSRKKLLQIIDTTLLKCYLHTNVALVSPLLRLENNHCHIEESEYVLKKAHKYSELIILYEKKGLHQKALQVLLDQSTKANSPLKGHE-----------RTVQYLQRLG-LENLGIIFEFSPWVLKICPEDGLKIFTEDLTEVETLPRD----QVLNFLKEGFKELAIPYLEHIIHMWDETRPEFHNVLIQLYLEKVQGLMKAYLNTLPEGIPAVAAGKEKGELGEFRNKLLSFLEVSSSYEPEILISDFPF-DGLLEERALLLGRMGKHEQALFIYVHILKDTRMAEEYCHG-HYDPATNGNKDVYLSLLRMYLSPPDVHFLGPIKMELCEPQANLQAALNVLQLHHSKLNTTKAINLLPANTQIREIQVFLESVLEEKAGRKRFDQVLKSLLQAEFLRVQEERIFHQQVKCVITDEKTCRVCKKKIG------NSAFARYPNGVVVHYFCCKD---------------------------RNTCPAE-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEA2-1", "uniprot_id": "VPS39_DROME", "id": "Q9VEA2-1", "name": "Vacuolar protein sorting-associated protein 39 homolog", "aln": "----------------------------------------------------------------MHQAYSVHSILKQG--------VQIESIAAYGNHVILGTRSGQLIMYSVDEETG----------------VDMRMFNKNFSRKPITQMEVIASENLLFVLTDLQVQVCDIRRIESNFAFMHSAPDTKGCTLFTMDVDT-PKSTTGRVATVIRVCCAIRRRLVFFFWKEDKLNSLELIIELSDVPRTLCWVGHAVCVGFKDE----------YVVYDISGKAPKKHNLFLTSSSIS---RDPCICLIRNNMLGISKDSYLVVVDPSQYKESDG-----------------------INNSTDVRPAAMDSNSSLTPLLWSSPLLDLVWDEPFAVGRVNNAIEVRSLVGKDTLVQTIP----ELQKTKFLVHADKGTIFAAATSELWCIRMVEIPIQRQQLLQQKKFQLAIELTQISDE-----------------PAADRAQTIRQIHMLYAKELFTNKEFSAAMKEFEKAAIDPYDVIRLFPNLVPEPKPGTEDVTVPTSSTPALEDSDLENAYLA--LIEYLAWARQREVVKLR--------------DTK---------------SSSKSLLEIIDTTLLKCYLQTNDSLVAPLLRLN--QCHLEESEKTLKKHNKISELIILYQMKGKHKEALKLLREQASIEGSVLQGRK-----------RTIRYLQELG-GDHLPLIFEFADWVLNDNPEEGLTIFTDELIEVESLPRA----KVLDFFISKHKALVIPYLEHVITEWKDGNTLLHNVLLKQYREKVQRLLAQ-----------QEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEEFPT-NILLEERALILGRLKKHDNVLSIYIHVLGDVAKATAYAEA-HYKE----DKHIFHTLIKCILIPPTQPLYDGVPLHPDFSQVNREVALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKSIRKMMADKHEMQMMCGFLEAESTRLENALEEQRNISFELNESSVCSECKKRFQT-----QSAFVRYPNGHIVHLSCHDR---------------------------LARAAAQQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3UR70-1", "uniprot_id": "TGFA1_MOUSE", "id": "Q3UR70-1", "name": "Transforming growth factor-beta receptor-associated protein 1", "aln": "--------------------------------------------------------------MMNIKAFTLVSAVERELLMGDRDHISIECVECCGRNLYVGTNDCFIYHFLLEEKAMPTGTA--------TFVATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLN---LEPVPSG-ARIKGATTFAVNESP-VNGDP---FCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTPEQPLAVAVDGYFLCLALTTQ----------YIILNYSTGLSQD--LFPYCSEE----KPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRA-----------------------PVHWSENVIGAAVCFP-------------------YVIALDDEFITVHSMLDQ-QQKQTL------PFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGARRNI---------------PKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSS------FTRSHPPLHEYADLNQLTQG--DQEKMAKCKRFLMSYLN--------------EIR-------------STEVANGYKEDIDTALLKLYAEADHDSLLDLLVTEN-FCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSD-----------LYEYIVDFLTYCLDQELVWTHADWLLQKSEEIGVQIFTKRPLDEQQQTSFN--PDNIISSLKKYPKALVKYLEHLVIDRRLQKEEYHTHLAILYLEEVLRQRVS-------------TGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKVQG-AGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQGAACRQRLFHTLLAMYLRAG------------PSAQDLTVAAVDLLNHHAREFDVTQVLQLLPDTWSVQLLCPFLMGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGNAVRLSERELCQLCQNPFG------EPVFVRYPNGGLVHTHCAAS-------------------------RHTAPSSPSPGTRT------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JV19-1", "uniprot_id": "A0A0G2JV19_RAT", "id": "A0A0G2JV19-1", "name": "", "aln": "MSGNVVPSPCSTTCLCGFLDPPFKLRLQTLHLQKVVTANLKIESLNWGAFQQEHFMPDYAVDMMNIKAFTLVSAVERELLMGDRDHISIECVECCGRNLYVGTNDCFIYHFLLEEKAMPTGTA--------TFIATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLN---LEPVPSG-ARIKGATTFAVNENP-VNGDP---FCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTTEQPLAVAVDGYFLCLALTTQ----------YIILNYSTGFSQD--LFPYCSEE----KPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRA-----------------------PVHWSENVIGAAVCFP-------------------YVIALDDEFITVHSMLDQ-QQKQTL------PFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGARRNI---------------PKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSS------FTRSHPPLHEYADLNQLTQG--DQEKMAKCKRFLMSYLN--------------EIR-------------STEVANGYKEDIDTALLKLYAEADHDSLLDLLVTEN-SCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSD-----------LYEYIVDFLTYCLDQELVWTHADWLLQKSQEVGVQVFTKRPLDEQQQTSFN--PDDIISCLKKYPKALVKYLEHLVIDRRLQKEEYHTHLALLYLEEVLRQRAP-------------TGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKIQG-AGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQDAACRQRLFHTLLAMYLRAG------------PSAHDLTVAAVDLLNHHAREFDATQVLQLLPDTWSVQLLCPFLTGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGSAIWLSEKKLCQLCQNPFG------EPVFVRYPNGGLVHTHCAAS-------------------------RHTNPSSPSPGTRT------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUH2-1", "uniprot_id": "TGFA1_HUMAN", "id": "Q8WUH2-1", "name": "Transforming growth factor-beta receptor-associated protein 1", "aln": "--------------------------------------------------------------MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPA--------TFTATKQLQRHLGFKKPVNELRAASALNRLLVLCDNSISLVNMLN---LEPVPSG-ARIKGAATFALNENP-VSGDP---FCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFLCLALTTQ----------YIIHNYSTGVSQD--LFPYCSEE----RPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRA-----------------------PVHWSENVIGAAVSFP-------------------YVIALDDEFITVHSMLDQ-QQKQTL------PFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNI---------------PKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSS------FTRSHPPLHEYADLNQLTQG--DQEKMAKCKRFLMSYLN--------------EVR-------------STEVANGYKEDIDTALLKLYAEADHDSLLDLLVTEN-FCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAVQLWVNIVNGDVQDSTRSD-----------LYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRPLDEQQKNSFN--PDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQRAS-------------ASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQG-AGLPMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLAIYLHAG------------PTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKGSSIQLSDKKLCQICQNPFC------EPVFVRYPNGGLVHTHCAAS-------------------------RHTNPSSSSPGTRT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG72-1", "uniprot_id": "TGFA1_DANRE", "id": "A4IG72-1", "name": "Transforming growth factor-beta receptor-associated protein 1 homolog", "aln": "---------------------------------------------------------------MSVKAFDLVPAVEREQVMGEKVRINIECIECCGQHLYLGTNDCFIHHFLLEEHTTAKGKL--------AFNAQKLLHKYLGLKKPVVELKAASALERLIVLCDSAITVVDMVT---LEPVPTGGAKLKGVTAFCINENP-VTGDA---FCVEMAVVLARRRAVQICTVHEDRVQMLKEVTTPEQPCALSLDGYNICLALSTQ----------YMILNYSTGASQD--LFPYDCEE----RKPIVKRIGREEFLLAAPGGLGMFANAEGISQRA-----------------------PVSWSENVIAAAVCFP-------------------YVVALDEGFVTVHSMLDQ-QLKQTL------SFRDGQLLQDFEGKVVVASSKAVYMLVPLPLERQIQDLLASHRVEEALTLTEAAQRNI---------------PKEKYQILHRRILQQAGFIQFGQLQFLEAKEHFRKGQLDVRELISLYPLLLPASSS------FTRCHPPLHEFADLNHLTQG--DQEKVQRFKRFLISYLH--------------EVR-------------SSDIANGFHEDVDTALLKLYAETSHESLLDLLASEN-ACLLADSAPWLEKHHKYYALGLLYHYNGQDAAALQMWVKIVNGDLQDSTRPD-----------LFEYVVDFLSFCSNLDLVWRHADWALQKDQKIGVQIFTKRPTSEERRGQLN--ADDVITYLQKHSQALLLYLEHLVLEKKLQKEKYHTHLAVLYAEKVLGLISR-------------PSTSEEQLSAARQKLQRLLKESNLYRVQLLLGKIQDSELLLLERATLHGKLEEHDKALHVLVHQLKDSSAAEEYCSWASASQDSSYRQNLFHQLLSVYLDPD------------VPGGAQTVAAVDLLNRHAEVFDAVRVLKLLPEDWSLPLLRPFLCGAMRATVHARCTSQVALGLARAQNLQLLHDRLKYRGGPVLVSEKKGCQLCHNTFS------EPDCACLPGGTPVHINCVAK-------------------------KALDLPHENAHHSNHT----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HR03-1", "uniprot_id": "A0AC58HR03_DANRE", "id": "A0AC58HR03-1", "name": "", "aln": "-----------------------------------------------------------------MQVFTPALVFQRTPSGKGRDKFSIQCLECFGKNLYIGTKEGAVEYLTVNN---PSSQQ--------SLTVREVGKRQMGRSGAIIKLTAIPVLNHLLVLWDGSITVLNMFS---LEALPAL-KKIPNVLLFAVSESG-IQRD-----SAELIVASSRRKTVSVYKVHVDRWECVKQVVLPQEPVLLAALGTCLCVATCDR----------YFLHDHQSQNTTD--LFLHNLGK----QNIIANKCGKGEFVLNGPGCLGMFVMKNGTSQHP-----------------------PVQLPDGVMDAAVHFP-------------------YVLALQNQSVHIYSILDQ-QLKQTV------PVHNARSLVPTEESVFIVTDKEIQRLSPVPLEDQIHELVNRQRVEEALTLLERLQHLL---------------PRDSYKDLHKNLICTSGMIKFYREAFVEAKELFIKGDLDPREIISLYPAMPVLSED------FTPQTTAVSNAKDLWTLSRN--DWPTFQQYLSFLDDFLR--------------EVK-------------PTAQGQTCLQDIDSALFKLYLEQGENEKLDQLVSTQNNCNLQMCVADLEQHKRFFTLGLLYQSQGQHFNAIQTWIKIVEDESEDPSNTS-----------VFQHIVKTLSNLEHKQIIWKFVDWVLRRDQEAGILIFTKTNAG--NHNTFV--PEEVFTILNSYPVALTLYLEYLVNESHSKEEKHHTMLITSYVKRILRSLAD-------------DHNNESSTEEMRHKLQQLLWQSSFYNADQIYDQIAS-SSLHVEQAISLGKNGKHKKALQVLVNEEKDQQAAECYCWRTSAGRDKKFTQTIFLTLLQIYLES----------------SHHVIAAVDLLNKNPESFDLSSVLMVLPESWSLKVVLRFLCESLRGTVHDKRMRGLEMSLAKVETLRHRHALMAATHEKIQVDRGCVCHSCQKRLT------GAEFLRRPTGELTHITCHNDPLFFIRGRHNEPPTYPAYVLSSRCPSSCNPSLGNTGKHPHTLVCTHTLRTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07468-1", "uniprot_id": "VAM6_YEAST", "id": "Q07468-1", "name": "Vacuolar morphogenesis protein 6", "aln": "--------------------MLRAQKLHSLKSSDITAILPTEQSQKLVLAKKNGDVEVYSRDGNTLKLFQVYPDLLQNAKNDPLPPVIENFYFANELSTIFAQCKETLILLSTTNLHEYDRIIDRR---GINHCWLFERSHKNKEEKNTYLIYSTINTAKMRVLIWEGRTYKNMMEASLSYRKETIRSIYPGETGITLATDLGIYHWPYNKPSLIRIEKTVKNKFPKDMISALTELKEQAEKVIEKKPKKNSHFDAQSFSSMDRMSRKSSMSSLWYRTIRNERGNKIRYTFELDGNDATPMIIDGATKKIFKVELMHNNEEPFLIATDHATFSESNSEFDHMQYLSSNLLMLYNSSTIKFVDYENGFTFLQQKIPEG---------------IKWVKNLSGTYFLVWTSNDEVQLFSYHVDDGSEDDDQESICGDINDPDFYQLWRKVLFYKFFIDSPHSKELCVSDNPEESLDICAMKLRDLTVMWCLRIFDKFQNYMVQLERSRNSRMIRSKCEEMIIKSIFDLFIKFWAPPQLVILKVFPSAISSLVLEITGQEHHCLLKEAEEVKETYDIPPHLLNRWCLPYLTDTRRHLQNLLSKENDDESRITWCYRDREIKQSFDFFLISNHDDVDLNTMLTLIDTVLFKCYLYYNPPMVGPFIRVEN-HCDSHVIVTELKIRHMFKDLIDFYYKRGNHEEALKFLTDLVDELENDNTDQKQRQKIDHGVKILVIYYLKKLS-NPQLDVIFTYTDWLLNRHNDSIKEILSSIFFYDSQACSSRDHLKVYGYIKKFDKLLAIQYLEFAISTFRLEGNKLHTVLIKLYLENLDIPSTR----------IKLKSLLETTSVYEPRTILKLLNDAIESGSDQLPTNQLN--FVKYLKIFPLSKLENHKEAVHILLDEIDDYKAATSYCNDVYQSDSTKGEELLLYLYSKLVSIYD--------------SNRNSKLILNFLQDHGSKLNSAEIYKNLPQDISLYDIGRVVSQLLKKHTSKMDETRLEKALLQVELVATTYKLNERMSSYGVLSDSHKCPICKKVISNFGTDSISWFTREGRNIITHYNCGKVLQER--------------------FNAKNEKSSRIKQKTLGEVINELNNK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : . : : * :: . : . :.: . . * . . * . : : . : . : . : : . . . : . : ::* . : :: : .: : . * : : .:: . :: . * : : :*:.*:* * . : * *: : * :* . . *:: . . . :. * . ::: . * *. . :::. . ***. : *. * * :.: .: :* : : : .: :*.:.: : :. * * *. : : ::.*: : :: ** : : : :. : : . : : * *:: : . . .* * ", "identical_positions": 36, "similar_positions": 135, "identity": "3.17%" }, { "cls_id": "homologset.agr.SGD:S000002236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04636-1", "uniprot_id": "MDHM_RAT", "id": "P04636-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPVGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVN-----------VPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VIECSFVQSK-------------ETECTYFSTPLLLGKKGLE--KNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08249-1", "uniprot_id": "MDHM_MOUSE", "id": "P08249-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPAGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVN-----------VPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VVECSFVQSK-------------ETECTYFSTPLLLGKKGLE--KNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40926-1", "uniprot_id": "MDHM_HUMAN", "id": "P40926-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPASAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVN-----------VPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEG--VVECSFVKSQ-------------ETECTYFSTPLLLGKKGIE--KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEB1-1", "uniprot_id": "Q9VEB1_DROME", "id": "Q9VEB1-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLKQVTKQLALQGVRTFSVGQQNN-YKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQ-----------IPVIGGHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKN--VIECSYVQST-------------VTEATFFSTPLVLGKNGVQ--ENLGLPKLNDYEKKLLEAAIPELKKNIQKGIDFANA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU29-1", "uniprot_id": "Q9VU29_DROME", "id": "Q9VU29-1", "name": "Malate dehydrogenase", "aln": "MFLASRLLSHVGNLPPKVQQLGYINRGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVN-----------IPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSKDECIVECAYVESD-------------VTEAQFFATPLILGPQGVK--ENTGLPDLDDEERKALNGMLPILKESIAKGIKLGEGMICSCA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32419-1", "uniprot_id": "MDHP_YEAST", "id": "P32419-1", "name": "Malate dehydrogenase, peroxisomal", "aln": "--------------------------MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQ-LDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:: *: **:********* .* :: *:**** : *:. *****:*.: : : : . :. .::*:****:*****:.*:**.. ** : : : .: .* * : .*:**:* :**.. :* * :.* .::**:.**:***.:*: . :. : :.*****:* **:*:::: .. :. : *:* .* *:*:** * ********:*.::*. .:: .::..: .::* .. :*: *::* .: .. : .: *.: : : *: .* ** .: ", "identical_positions": 97, "similar_positions": 114, "identity": "26.01%" }, { "cls_id": "homologset.agr.SGD:S000002237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18265-1", "uniprot_id": "GSK3A_RAT", "id": "P18265-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-------------------------------------------------------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRSLG-TQLPNNRPLPPLFNFSPGELSIQPSLNAILIPPHLRSPSG-----PATLTSSSQALTETQTGQDWQAPDAT-PTLTNSS-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49840-1", "uniprot_id": "GSK3A_HUMAN", "id": "P49840-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-------------------------------------------------------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLG-TQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAG-----TTTLTPSSQALTETPTSSDWQSTDAT-PTLTNSS-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2NL51-1", "uniprot_id": "GSK3A_MOUSE", "id": "Q2NL51-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-------------------------------------------------------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATVGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKSSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRRLG-AQLPNDRPLPPLFNFSPGELSIQPSLNAILIPPHLRSPAGPASPLTTSYNPSSQALTEAQTGQDWQPSDATTATLASSS-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV60-1", "uniprot_id": "GSK3B_MOUSE", "id": "Q9WV60-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------------------------------------MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASPPANATAASDTNAGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18266-1", "uniprot_id": "GSK3B_RAT", "id": "P18266-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------------------------------------MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDMWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASPPANATAASDTNAGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49841-1", "uniprot_id": "GSK3B_HUMAN", "id": "P49841-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------------------------------------MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASTPTNATAASDANTGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVR7-1", "uniprot_id": "A0A8M3AVR7_DANRE", "id": "A0A8M3AVR7-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------------------------------------MSG------------RPRTTSFAES-----------CKPVPQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGDKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPMVYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVSKQVFRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELREPN-VKLPNGREKPSLFNFTTQELSSNPTLASILIPAHARNQAG------ASTPTNPSATSDANSGDRSQTTTAASASASNTST------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18431-2", "uniprot_id": "SGG_DROME", "id": "P18431-2", "name": "Protein kinase shaggy", "aln": "-------------------------------------------------------MSG------------RPRTSSFAEG------------NKQSPSLVLGGVKTCS-----------------------------------------RDGSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKV----FRI-RTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQNASGP----GGNRPSAGGAASIAASGSTSVSSTGSGASVEGSAQPQSQGTAAAAGSGSGGATAGTGGASAGGPGSGNNSSSGGASGAPSAVAAGGANAAVAGGAGGGGGAGAATAAATATGAIGATNAGGANVTDS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83101-1", "uniprot_id": "GSK3H_DROME", "id": "P83101-1", "name": "Putative glycogen synthase kinase-3 homolog", "aln": "---------------------------------------------------------------------------------------------MASQSKNSG------------------------------------------------LTNKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLG-FCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKV----FRI-RTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQGSSTTKEPSAAHRNRNTAGEESPRKTEDSQKPATAALSKSPGPSGKALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAVGEDAEDNLEEDVGDENDYDYDDGGQCNSTYISDDMDEASESDDDDFEEEDEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50873-1", "uniprot_id": "MRK1_YEAST", "id": "P50873-1", "name": "Serine/threonine-protein kinase MRK1", "aln": "MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTIKKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDGKVANKHENISSKLSKEKVEKMIN----------FDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEE-DEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEI----FKA--EDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEERLKHFVS--------APSSSL--------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * . . . :::*. :*:*:****** : : : : *********:*:*****: *: * * * : * ::*:...:: **::****::::*:::*: *:: . * * ::.* ***:::: *:*. .*********:*:*. * :*:******* * .:****************:**: :*:..:*:**:.**::*****: :*.*:**:**:**::*::* ** ::: ***:* :. :*::*. . :: *: .::: * : * * * *: ** .:*** : : : : * * : ", "identical_positions": 130, "similar_positions": 107, "identity": "20.06%" }, { "cls_id": "homologset.agr.SGD:S000002239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0H2UHJ3-1", "uniprot_id": "A0A0H2UHJ3_RAT", "id": "A0A0H2UHJ3-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELTCIYSDLILH--DEVMVTEDKINALIKAAGVNVELFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSTVAAP--AEEKKVEAKKEE-SEESEDDTSFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A494BA26-1", "uniprot_id": "A0A494BA26_MOUSE", "id": "A0A494BA26-1", "name": "Large ribosomal subunit protein P1", "aln": "MASASELACIYSALILHEDDEVMVTEDKINALIKAA--LIKPFWPSLFAKALANVNIGSLICSVGAGGPAPAAGAAPAGSPAPSTAAAP--AEEKKVETKKEE-SEEFEDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19944-1", "uniprot_id": "RLA1_RAT", "id": "P19944-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSAAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05386-1", "uniprot_id": "RLA1_HUMAN", "id": "P05386-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSTAAAP--AEEKKVEAKKEE-SEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47955-1", "uniprot_id": "RLA1_MOUSE", "id": "P47955-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVSVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGAAPSTAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08570-1", "uniprot_id": "RLA1_DROME", "id": "P08570-1", "name": "Large ribosomal subunit protein P1", "aln": "MSTKAELACVYASLILV-DDDVAVTGEKINTILKAANVEVEPYWPGLFAKALEGINVKDLITNIGSG-----VGAAPAGGAAPAAAAAAPAAESKKEEKKKEEESDQSDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05318-1", "uniprot_id": "RLA1_YEAST", "id": "P05318-1", "name": "Large ribosomal subunit protein P1A", "aln": "MSTESALS--YAALILA-DSEIEISSEKLLTLTNAANVPVENIWADIFAKALDGQNLKDLLVNFSAG------AAAPAG-VAGGVAGGE--AGEAEAEKEEEEAKEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : *: *: *** .:: :: :*: :: :** :: *..:***** . *: .*: ...:* .***** * ..... * . : * ::** .:: :** .*****", "identical_positions": 35, "similar_positions": 43, "identity": "29.66%" }, { "cls_id": "homologset.agr.SGD:S000002240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47963-1", "uniprot_id": "RL13_MOUSE", "id": "P47963-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41123-1", "uniprot_id": "RL13_RAT", "id": "P41123-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26373-1", "uniprot_id": "RL13_HUMAN", "id": "P26373-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPVRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z10-1", "uniprot_id": "RL13_DANRE", "id": "Q90Z10-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILNPHFHKDWQKRVRTWFNQPARKIRRRKARQAKARRIAPRPVSGPLRPVVRCPTIRYHTKVRAGRGFTLEELKAAGINKKVARTIGISVDSRRRNRSTESLQANVQRLKEYRTKLIIFPRKAAKPKKGDSTEEELKMATQLTGPVMPIKK-VHKKEKARVISEDEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41126-1", "uniprot_id": "RL13_DROME", "id": "P41126-1", "name": "Large ribosomal subunit protein eL13", "aln": "MGKG-NNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAFATLRKARTDARLVGIRAKRAKEAAESEDAAKGDPKKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12690-1", "uniprot_id": "RL13A_YEAST", "id": "Q12690-1", "name": "Large ribosomal subunit protein eL13A", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRN------GKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * : : *::* **.:* . *:*..:*: *: * :* : *** . :**:**.**::*: *:******:* *:: **: *:****:** **:*:. * : *:******::*:*:** : *.:. * ::: . :*: : : * : .: : .** :** **:: :: *** ***:* ** :. * ** ", "identical_positions": 78, "similar_positions": 65, "identity": "35.62%" }, { "cls_id": "homologset.agr.SGD:S000002241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62249-1", "uniprot_id": "RS16_HUMAN", "id": "P62249-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62250-1", "uniprot_id": "RS16_RAT", "id": "P62250-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14131-1", "uniprot_id": "RS16_MOUSE", "id": "P14131-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R8S7-1", "uniprot_id": "M0R8S7_RAT", "id": "M0R8S7-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGCKKTATAVAHCKGGNGLIKVNGRSLEMIELCTLQYKLLEPVLHLGKERFAGVDIQVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYNPTLPVADPRRCESKKFGSPGARALYQKSYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W237-1", "uniprot_id": "RS16_DROME", "id": "Q9W237-1", "name": "Small ribosomal subunit protein uS9", "aln": "MQQKRREPVQAVQVFGRKKTATAVAYCKRGNGLLKVNGRPLEQIEPKVLQYKLQEPLLLLGKEKFAGVDIRVRVSGGGHVAQIYAIRQAISKALVAFYQKYVDEASKKEIKDILVQYDRTLLVGDPRRCEPKKFGGPGARARYQKSYR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX52-1", "uniprot_id": "RS16B_YEAST", "id": "P0CX52-1", "name": "Small ribosomal subunit protein uS9B", "aln": "MSAVP-----SVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.** **:*****: * *:**:**** .: :* *::*: **:* :* ::*:.:**:***.*****:*:*****:*:*.***::****** **:*:*. : .*: ** :.*.** *.****. ***: :*****", "identical_positions": 78, "similar_positions": 41, "identity": "52.7%" }, { "cls_id": "homologset.agr.SGD:S000002242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1N5-1", "uniprot_id": "DX39B_MOUSE", "id": "Q9Z1N5-1", "name": "Spliceosome RNA helicase Ddx39b", "aln": "MAENDVDNELLDYEDDEV------ETAAG------------ADGTEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTG-QVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN--CPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDE-IDISSYIEQTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63413-1", "uniprot_id": "DX39B_RAT", "id": "Q63413-1", "name": "Spliceosome RNA helicase Ddx39b", "aln": "MAENDVDNELLDYEDDEV------ETAAG------------ADGTEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTG-QVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN--CPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDE-IDISSYIEQTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13838-1", "uniprot_id": "DX39B_HUMAN", "id": "Q13838-1", "name": "Spliceosome RNA helicase DDX39B", "aln": "MAENDVDNELLDYEDDEV------ETAAG------------GDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTG-QVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN--CPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDE-IDISSYIEQTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXU7-1", "uniprot_id": "Q7SXU7_DANRE", "id": "Q7SXU7-1", "name": "RNA helicase", "aln": "MTENDVDNELLDYEEDEV------DAGGAG-----DAGLGHSDGIISIRKEGVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTG-QVSVLVMCHTRELAFQISKEYERFSKYMPSVKVAVFFGGLSIKKDEEVLKKE--SPHVVVGTPGRILALSRNKSLNLRHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRAMPQDERLARYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDARTLNDVQDRFEVNISELPEE-IDISSYIEQTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VDW0-1", "uniprot_id": "DX39A_MOUSE", "id": "Q8VDW0-1", "name": "ATP-dependent RNA helicase DDX39A", "aln": "MAEQDVENELLDYDEDEE------PQAPQ-------------ESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNG-QVSVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKN--CPHVVVGTPGRILALVRSRSLNLRNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDENDAKILNDVQDRFEVNVAELPEE-IDISTYIEQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U216-1", "uniprot_id": "DX39A_RAT", "id": "Q5U216-1", "name": "ATP-dependent RNA helicase DDX39A", "aln": "MAEQDVENELLDYDEDEE------PQVPQ-------------ESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPING-QVSVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKN--CPHVVVGTPGRILALVRSRSLNLRNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDENDAKILNDVQDRFEVNVAELPEE-IDISTYIEQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00148-1", "uniprot_id": "DX39A_HUMAN", "id": "O00148-1", "name": "ATP-dependent RNA helicase DDX39A", "aln": "MAEQDVENDLLDYDEEEE------PQAPQ-------------ESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNG-QVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKN--CPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEE-IDISTYIEQSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27268-1", "uniprot_id": "DX39B_DROME", "id": "Q27268-1", "name": "ATP-dependent RNA helicase WM6", "aln": "MADND---DLLDYEDEEQ------TETTA------------VENQEAP-KKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSG--TPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDVNISELPEE-IDLSTYIEGR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07478-1", "uniprot_id": "SUB2_YEAST", "id": "Q07478-1", "name": "ATP-dependent RNA helicase SUB2", "aln": "-MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPG-EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLNN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :**:*.::* :. . **:**.***:**:*******: ***:***********:. ***:: * *:*******:********:****::* . *:*:*::****:** :** ******* **.:**:** .*.** : **. **:**.****: ** *.: :.* :*:*::*****:**:************ **: ** ********::***:*::*:*:*:*::****:*********:*::*:: ***:** :*** ******:*****. *. *::** .***** :* * *:**: **: ****::** *:*::****:****:*:.:***:.:::* *****.***********::***.::* . * .:*:**:*:::*:*:* ** *:*:: ", "identical_positions": 244, "similar_positions": 116, "identity": "54.22%" }, { "cls_id": "homologset.agr.SGD:S000002245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9R0-1", "uniprot_id": "G3V9R0_RAT", "id": "G3V9R0-1", "name": "", "aln": "-------MSAQAQMRALLDQLMG-----TARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLF--FELDAMDHLESFIAECDRRTELAKKR---LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRSKKKEAEEEYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIQIREKLDQLRKTVA-EKQEKRNQDRLRRREE--REREERLGRR---------SGSRTRDRRRSRSR----------------DRRRRRSRSTSRERRKFSRSRSRD-RYR-------RHRSRSRSHSRGHRRA-----SRDR-STKYKFSRER-SLREESWEYRRNERGPTDWRLENSNGKTASRR-EHHDCFLSLSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYI4-1", "uniprot_id": "LUC7L_MOUSE", "id": "Q9CYI4-1", "name": "Putative RNA-binding protein Luc7-like 1", "aln": "-------MSAQAQMRALLDQLMG-----TARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLF--FELDAMDHLESFIAECDRRTELAKKR---LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIQIREKLDQLRKTVA-EKQEKRNQDRLRRREE--REREERLGRR---------SGSRTRDRRRSRSR----------------DRRRRRSRSTSRERRKFSRSRSRD-RYR-------RHRSRSRSHSRGHRRA-----SRDR-STKYKFSRER-SLREESWEYGRNERGPTDWRLENSNGKTASRR-SEEKEAGEI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ29-1", "uniprot_id": "LUC7L_HUMAN", "id": "Q9NQ29-1", "name": "Putative RNA-binding protein Luc7-like 1", "aln": "-------MSAQAQMRALLDQLMG-----TARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLF--FELDAMDHLESFIAECDRRTELAKKR---LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIQIREKLDQLRKTVA-EKQEKRNQDRLRRREE--REREERLSRR---------SGSRTRDRRRSRSR----------------DRRRRRSRSTSRERRKLSRSRSRD-RHR-------RHRSRSRSHSRGHRRA-----SRDR-SAKYKFSRER-ASREESWESGRSERGPPDWRLESSNGKMASRR-SEEKEAGEI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y383-1", "uniprot_id": "LC7L2_HUMAN", "id": "Q9Y383-1", "name": "Putative RNA-binding protein Luc7-like 2", "aln": "-------MSAQAQMRAMLDQLMG-----TSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVAKKR---LAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIEIREKLEELKRVVA-EKQEKRNQERLKRREE--REREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSR------------ERKRR-TRSKSREKRHRHRSRSSS-RSRSRSHQRSRHSSRDRSRERSKRRS-----SKERFRDQDLASCDR-DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNC4-1", "uniprot_id": "LC7L2_MOUSE", "id": "Q7TNC4-1", "name": "Putative RNA-binding protein Luc7-like 2", "aln": "-------MSAQAQMRAMLDQLMG-----TSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVSKKR---LAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIEIREKLEELKRVVA-EKQEKRNQERLKRREE--REREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSR------------ERKRR-TRSKSREKRHRHRSRSSS-RSRSRSHQRSRHSSRDRSRERSKRRS-----SKERFRDQDLASRDR-DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XLZ3-1", "uniprot_id": "A0A8J8XLZ3_RAT", "id": "A0A8J8XLZ3-1", "name": "RNA-binding protein Luc7-like", "aln": "-------MPAYFNLQGSFRKAP------HSPSRDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVSKKR---LAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIEIREKLEELKRVVA-EKQEKRNQERLKRREE--REREEREKLR----------RSRSREHRRHRSRSMSR------------ERKRR-TRSKSREKRHRHRSRSSS-RSRSRSHQRSRHSSRDRSRERSKRRS-----SKERFRDQDLASRDR-DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BA63-1", "uniprot_id": "A0A8M2BA63_DANRE", "id": "A0A8M2BA63-1", "name": "", "aln": "---MVQCMFASLHLQGSCRKAS------CSSSRDESRQRVKFTDERVCKSHLLNCCPHDILSGTRMDLGECSKIHDLALRADYEIASKERDLF--FELDAVDHLESFIADCDRRTELAKKR---LAETQEEISAEVAQKAEKVHELNEEIGKLLAKAEQLGAEGNVDEAQEVLQEVEKVRSRKKDAEEEYRNSMP-ASSFQQQK-----LRVCEVCSAYLGLHDND-----------RRLADHFGGKLHLGFIQIREKLEQLKKTVQ-DKQERRNQERLKRREE--REREERMKKR---------TRSRSRDRKRSRSRERDR------------ERRRRRSRSASREKR---RSRSRS-KERDR---RRRHRSRSRSRSRHSREQ-----SHK-------SSRDR-DRE------RDTKRSSSERRSDGLNGRTESRR-HDDREAGEI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVI1-1", "uniprot_id": "LUC7L_DROME", "id": "Q9VVI1-1", "name": "Putative RNA-binding protein Alsin2", "aln": "MSAPSNKMSATDQMRAMLDQLMG-----TTRNGDE-RQ-LKFSDPRVCKSFLLDCCPHDILASTRMDLGECPKVHDLAFRADYESAAKTRDYY--YDIEAMEHLQAFIADCDRRTDSAKQR---LKETQEELTAEVAEKANAVHGLAEEIGKKLAKAEALGEAGEVEDSMELMKEIEELRAKKIKAEHEYRTSMP-ASTYQQQK-----LRVCEVCSAYLGIHDND-----------IRLADHFGGKLHLGFLTIREKLIELEKTAAPRKAELKRTGKMTDREDEGRGRNRYFVGGRELDRRSRVHRSRSRERQRNRDGDRERPNNGRGPEEKGSERPKEAADGPERAERAPDRGGRRDDRDNHGRDHRERERDGRRDRDRHGRNDRGRFGDRGGGGGGGGHHRDD-RRRSRSRERSPRERRNFNHFRDGGGGGNGQRKRSYSRERNYRR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07508-1", "uniprot_id": "LUC7_YEAST", "id": "Q07508-1", "name": "Protein LUC7", "aln": "---MSTMSTPAAEQRKLVEQLMGRDFSFRHNRYSHQKRDLGLHDPKICKSYLVGECPYDLFQGTKQSLGKCPQMHLTKHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQN---LKHTAEER-MKIQQVTEELDVLDVRIGLMGQEIDSLIRADEVSMGMLQSVKLQELISKRKEVAKRVRNITENVGQSAQQK-----LQVCEVCGAYLSRLDTD-----------RRLADHFLGKIHLGYVKMREDYDRLMKNNRTTNASKTATTLPGRRFV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3X8-1", "uniprot_id": "Q9W3X8_DROME", "id": "Q9W3X8-1", "name": "Luc7-like protein 3", "aln": "---------MVDAARQMLDELMGRN---RNLHPSEAGAKVNWEDPEFCQFYNVKFCPHDLFINTRADLGPCARIHDEEARHLYEDARPSQRKR-QYEDEFLRFCNVMLHDVDRKIQKGKQRLLLMQRDQPNVPAPLSRHQEQLANLTARINKLLSEAEEAGIRGDVDQAQDLMTVCEELKEEKEQLVQQYEAHHKAISSISLTKSAEDELQHHPRSSPVTNPSEESPTTPLPAATTLDEAPDAAPSSAQAAVTTTDDAGEAAGAASEDKTSEKTDSKAAGWSHDAMPEKQMKVCEICGAFLIVGDAQQRIEDHLMGKQHLGYSKLRNAVAEINEARQKEREQEERRRREGRVQRFHSYDSRREPRSEYRERSRDYVQNRQPSDRRHHHHKSHHSSHHSYSRSGGGGGGVGVGGGGGGGSSRSNRSHHNHNHNHYRHDSRERHCRSRSRSRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : * ..*: . : **:*:: .*: .** * ::* : ** :: : : . :: : : : . . :. : . : : : : * .*. : : .:*. . :: .: . . . . * *: ... . : . . .* .. : . : . . ", "identical_positions": 18, "similar_positions": 70, "identity": "3.99%" }, { "cls_id": "homologset.agr.SGD:S000002248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49356-1", "uniprot_id": "FNTB_HUMAN", "id": "P49356-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDS---VETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQ--REKHFHYLKRGLRQ-LTDAYECLDASRPWLCYWILHSLELLD-EPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIG-TEEAYDIINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCAASVASLTNIITP---DLFEGTAEWIARCQNWEGGIGGVPGM-EAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQ-CPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2I1-1", "uniprot_id": "FNTB_MOUSE", "id": "Q8K2I1-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MASSSSFTYYCPPSSSPVWSEPLYSLRPEHVRERLQDDS---VETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQ--REKHFHYLKRGLRQ-LTDAYECLDASRPWLCYWILHSLELLD-EPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIG-TEEAYNVINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCAASVASLTNIITP---DLFEGTAEWIARCQNWEGGIGGVPGM-EAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQ-CPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDMVMGVPENVLQPTHPVYNIGPEKVIQATTHFLQKPVPGFEECEDEVTSDPATD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VEV7-1", "uniprot_id": "Q9VEV7_DROME", "id": "Q9VEV7-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MGTEEELMFRN--------FQRLKSY-------IFDDEK---VSTTTSREQQKTESSVEKCFDRFEQIMFTDPRLTQIFRLEHQYYLDAMLRR-LPSNYECLDSSRAWCVYWILQAAQLLS-FNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAPTYAAVNSLCIIG-SEQAYRAIDRPTLVQFLFSVRDSDGSFRLHVDG-ETDVRGAYCAISCAKLLNLPEPVIKELFAGTGDWIAQCQTYEGGFGGAPGL-EAHGGYTFCGIAGLALLNEADKCDRQALLKWTLRRQMTYEGGFQGRTNKLVDGCYSFWVGATIPITQATLSG---VDKQMEHTLFDVEALQEYILLCCQ-KQSGGLIDKPGKPQDLYHTCYTLSGVSIAQHSECASSPQ--VLGDTINELLPTHPLFNIPPKSVAAARSHFSNSNDTEFLG-KDSPSKEES--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22007-1", "uniprot_id": "FNTB_YEAST", "id": "P22007-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MRQRVGRSIARAKFINTALLGRKRPVMERVVDIAHVDSSKAIQPLMKELETDTTEARYKVLQSVLEIYDDEKNIEPALTKEFHKMYLDVAFEISLPPQMTALDASQPWMLYWIANSLKVMDRDWLSDDTKRKIVDKLFTISPSGGPFGGGPGQLSHLASTYAAINALSLCDNIDGCWDRIDRKGIYQWLISLKEPNGGFKTCLEVGEVDTRGIYCALSIATLLNILTE---ELTEGVLNYLKNCQNYEGGFGSCPHVDEAHGGYTFCATASLAILRSMDQINVEKLLEWSSARQLQEERGFCGRSNKLVDGCYSFWVGGSAAILEAFGYG----------QCFNKHALRDYILYCCQEKEQPGLRDKPGAHSDFYHTNYCLLGLAVAESSYSCTPND-----SPHNIKCTPDRLIGSSKLTDVNPVYGLPIENVRKIIHYFKSNLSSPS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0L564-1", "uniprot_id": "A0ABK0L564_RAT", "id": "A0ABK0L564-1", "name": "Protein Churchill", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCG------DCVEK----------KYPN--------------RGNTCLENGSFLLN------------------------------------FAGCAVCSKRDFMLITN------RSLKEEDGEEIVTYDHLCKNCHHVIARHEYTFSIMDEFQVLQEALKG-------------------GTSPTCCP------------------------CSLPTCRFCSSSALFP-------MRIFWTPSGAY------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: : .: *. * . : * * ..* :.*. : :: . * : . : : . : :. *:* : . . ** .:. .. . : . .. ", "identical_positions": 11, "similar_positions": 42, "identity": "2.44%" }, { "cls_id": "homologset.agr.SGD:S000002249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54731-1", "uniprot_id": "FAF1_MOUSE", "id": "P54731-1", "name": "FAS-associated factor 1", "aln": "------MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSDFGGETMPGPTFDPASHPAPASTPSSS-AFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDSCTVGEIKQILENELQIPVPKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTVQEVKRNVYDLTSIPVRHQLWEGWPASATDDSMCLAESGLSYPCHRLTVGRRTSPVQTREQSEEQSTDVHMVSDSDGDDFEDASEFGVDDGEVFGMASSTLRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESV--LTNVFCSQMLCAESIVSYLS-QNFITWAWDLTKDTNRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKRSS-NEVLNVIQGNTTVDELMMRLMAAMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD----RAKREAHEREMAEQFRLEQIRKEQEEEREAIR---LSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGF---PWDEFKLLSTFPRRDVTQLD----PNKS----------LLEVNLFPQETLFLQAKE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924K2-1", "uniprot_id": "FAF1_RAT", "id": "Q924K2-1", "name": "FAS-associated factor 1", "aln": "------MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSDFGGETMPGPTFDPASPPAPAPAPSSS-AFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDSCTVGEIKQILENELQIPVPKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTVQEVKRNVYDLTSIPVRHQLWEGWPASATDDSMCLAESGLSYPCHRLTVGRRTSPVQTREQSEEQSTVVHMVSDSDGDDFEDASEFGVVDGEVFGMASSTMRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESV--LTNVFCSQMLCAESIVSYLS-QNFITWAWDLTKDANRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKRSS-NEVLNVIQGNTTVDELMMRLMAAMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD----RAKREAHEREMAEQFRLEQIRKEQEEEREAIR---LSLEQALPPEPEEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGF---PWDEFKLLSTFPRRDVTQLD----PNKS----------LLEVNLFPQETLFLLAKE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNN5-1", "uniprot_id": "FAF1_HUMAN", "id": "Q9UNN5-1", "name": "FAS-associated factor 1", "aln": "------MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGWPTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESV--LTNVFCSQMLCAESIVSYLS-QNFITWAWDLTKDSNRARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSS-NEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD----RAKREAHEREMAEQFRLEQIRKEQEEEREAIR---LSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGF---PWDEYKLLSTFPRRDVTQLD----PNKS----------LLEVKLFPQETLFLEAKE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TDN2-1", "uniprot_id": "FAF2_MOUSE", "id": "Q3TDN2-1", "name": "FAS-associated factor 2", "aln": "MAAPEEQDLTQEQTEKLLQFQDLTGIESMEQCRLALEQHNWNMEAAVQDRLNEQEGVPSVFNPPP---------------------ARPLQVNTADHRIYSYVV----------------------------------------------------------------------------SRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRFIRP--------------------------------------------------------------------DPRSRVTDPVGD---------------------------------------IVSFMHSFEEKYGRAHPVFYQG----TYSQALNDAKRELRFLLVYLHGDDHQ--DSDEFCRNALCAPEVISLIN-SRMLFWACSTNKPEG----------------YRVSQALRENTYPFLAMIMLKDRR-MTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREEKERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPE-SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKE---SPEKFQIEANFPRRVLPCVPSEEWPNPP---------TLQEAGLSHTEVLFVQDLTDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK32-1", "uniprot_id": "FAF2_RAT", "id": "Q5BK32-1", "name": "FAS-associated factor 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPFRFTYYTILDIFRFALRFIRP--------------------------------------------------------------------DPRSRVTDPVGD---------------------------------------IVSFMHSFEEKYGRAHPVFYQG----TYSQALSDAKRELRFLLVYLHGDDHQ--DSDEFCRNALCAPEVISLIN-SRMLFWACSTNKPEG----------------YRVSQALRENTYPFLAMIMLKDRR-MTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPD-SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKE---SPEKFQIEANFPRRVLPCVPSEEWPNPP---------TLQEAGLSHTEVLFVQDLTDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CS3-1", "uniprot_id": "FAF2_HUMAN", "id": "Q96CS3-1", "name": "FAS-associated factor 2", "aln": "MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSVFNPPP---------------------SRPLQVNTADHRIYSYVV----------------------------------------------------------------------------SRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRFIRP--------------------------------------------------------------------DPRSRVTDPVGD---------------------------------------IVSFMHSFEEKYGRAHPVFYQG----TYSQALNDAKRELRFLLVYLHGDDHQ--DSDEFCRNTLCAPEVISLIN-TRMLFWACSTNKPEG----------------YRVSQALRENTYPFLAMIMLKDRR-MTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPE-SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKE---SPEKFQIEANFPRRVLPCIPSEEWPNPP---------TLQEAGLSHTEVLFVQDLTDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ58-1", "uniprot_id": "Q9VJ58_DROME", "id": "Q9VJ58-1", "name": "", "aln": "---MEADGLTNEQTEKVLQFQDLTGIEDMNVCRDVLIRHQWDLEVAFQEQLNIREGRPTMFAASTDVR--------APAVLNDRFLQQVFSANMPGGRTVSRVP----------------------------------------------------------------------------SGPVPRSFTGIIGYVINFVFQYFYSTLTSIVSAFVNLGGG--------------------------------------------------------------------NEARLVTDPLGD---------------------------------------VMKFIREYYERYP-EHPVFYQG----TYAQALNDAKQELRFLIVYLHKDPAKNPDVESFCRNTLSARSVIDYIN-THTLLWGCDVATPEG----------------YRVMQSITVRSYPTMVMISLRANR-MMIVGRFEGDCTPEELLRRLQSVTNANEVWLSQARADRLERNFTQTLRRQQDEAYEQSLLADEEKERQRQRERDAVRQAEEAVEQARRDVELRKEEIARQKIELATLVPSEPAADAVG-AIAVVFKLPSGTRLERRFNQTDSVLDVYHYLFCHPD---SPDEFEITTNFPKRVLFSKANLDAAGETGTAKETLTKTLQAVGLKNREVLFVNDLEA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12229-1", "uniprot_id": "UBX3_YEAST", "id": "Q12229-1", "name": "UBX domain-containing protein 3", "aln": "--MDIFRHTFGNNDDSFIRIPGAFREEPPADLNGRTEDQNSNTNEPTQSRDGRLKSILHFLFQAP-----------------LIVLYYLLNFIVRSSRLLKPLLR--------------------------------------------------------------------------LHGFYQRKHNRLLDHSSQLHRLLENLENEAQAVTCSEGNGN--------------------------------------------------------------------NDDGSNTDSTSNN-------------------------------------ESSGVQFSFGSLYNPENGTFSKSIMQNSYTELLDACSEQVKFGVIYLHDPLLD--NHMDYVNKILCSEAFVNMIRKYQVLLWYGDVTTSEG----------------LQVSNALKIRQYPLLGIISLKAEKKIELIARVEGSIS-NYKAQDLEAIFSKNYSRLIQLRQQRQNIEMQRLIRQQQDSRYQDSLRRD-----QQRESERLEQTQREQMEREHQRIENQWLLWR------KSQLKPEPSSDKDA--SKVAIRLENGQRLVRKFDASLPTEEIYAFVELQLHDMLNSENDTLPVYQPANYQHQYSFKLITPVPRRELDLSTKISDVSGIYPSGNIVMERLDE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. .: . .: . * : .* . :: : : .: :: :*** : : *.: .:. : . : * . . . :. .: :* : :* : :: .:* : * . . :. : : . ::::**. * ** * ::. . . ::: : * . : .** : : :: .. : *:* : :. :: :: : * . . . : :.: ", "identical_positions": 24, "similar_positions": 94, "identity": "3.5%" }, { "cls_id": "homologset.agr.SGD:S000002250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6U5-1", "uniprot_id": "A0A8I5Y6U5_RAT", "id": "A0A8I5Y6U5-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RSSGSVFITLK------------KYDGRTKP---IPRKS---SVEGLEPAENKCLLRAT----DGKRKISTVVSSKEVNKFQMECEACSSLWNTSQELLKECRHRGTRVASIGVAVGFLMPATLSPMESLLLPSLYLFLLRPCSGFQAYSNLLRANMDGLKKRDKKNKSKKSKPAQ--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16254-1", "uniprot_id": "SRP14_MOUSE", "id": "P16254-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RSSGSVFITLK------------KYDGRTKP---IPRKS---SVEGLEPAENKCLLRAT----DGKRKISTVVSSKEVNKFQM----------------------------------------------------------------AYSNLLRANMDGLKKRDKKNKSKKSKPAQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37108-1", "uniprot_id": "SRP14_HUMAN", "id": "P37108-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RTSGSVYITLK------------KYDGRTKP---IPKKG---TVEGFEPADNKCLLRAT----DGKKKISTVVSSKEVNKFQM----------------------------------------------------------------AYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDL0-1", "uniprot_id": "Q9VDL0_DROME", "id": "Q9VDL0-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLDNSNFILRLEKIANAA-KKDSSFTLTFK------------RYDGNDKP---VPREG---RPPLPKPETYMCLMRAQ----SKSQKISTVVRQEDVPAMMS----------------------------------------------------------------MYSQFMKSKMDGLKRVKKVKSKAKATKG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38985-1", "uniprot_id": "SRP14_YEAST", "id": "P38985-1", "name": "Signal recognition particle subunit SRP14", "aln": "MANTGCLSPGAFLSKVPEFFQTANEKHITVRLTAKRLIEHDPVEGNLEFDSTNHPDYDVSKKASEISVSSRSDREYPLLIRMSYGSHDKKTKCSTVVKASELDQFWQ----------------------------------------------------------------EYSSVFKGGMQNLIKKKKKKSKNGTISKTGKKNKVAKKN----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *: .: .: : . .. :. :* * .:*. :* :.::. . *:* . . * **** .:: : **..::. *:.* : .* :.. : ", "identical_positions": 18, "similar_positions": 43, "identity": "7.96%" }, { "cls_id": "homologset.agr.SGD:S000002255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMZ8-1", "uniprot_id": "PSD11_RAT", "id": "F1LMZ8-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00231-1", "uniprot_id": "PSD11_HUMAN", "id": "O00231-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG32-1", "uniprot_id": "PSD11_MOUSE", "id": "Q8BG32-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYSKAKKLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6P3G4-1", "uniprot_id": "PS11A_DANRE", "id": "F6P3G4-1", "name": "26S proteasome non-ATPase regulatory subunit 11A", "aln": "-MAATAVEFQRAQSLLSTDR-NASIDILHAIVKRDVQ--------DDDEEAVRVKEQSILELGGLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDMFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALQLGSQLLQELKKMDDKALLVELQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQAALDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----RAITALKYMLLCKIMLNSPEDVQSLISGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTEYKAELRDDPIISTHLTKLYDNLLEQNLIRVIEPFSRVQIEHISELIKLSKGDVERKLSQMILDQKFHGILDQGEGVLIVFDEPPVDKTYEASLETIQNMSKVVDSLYNKAKKLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QGH9-1", "uniprot_id": "PS11B_DANRE", "id": "F1QGH9-1", "name": "26S proteasome non-ATPase regulatory subunit 11B", "aln": "MAAAAVVEFQRAQSLISTDR-NASIDIFHSIVRRDVQ--------EDDEEAVRVKEQSILELGSLLAKTGQAAELGGLLKFVRPFLISISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKAEKRTFLRQALEARLISLYFDTKRYQEALQLESQLLQELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQAALDMQSGIIHAAEEKDWKTAYSYFFEAFEGYDSIDSP----RAVTALKYMLLCKIMLSLPEEVQALISGKLGLR-YAGRQTDALKCIAQASKNRSLADFEKALTEYTKELRDDPIINTHLAKLYDNLLEQNLIRVIEPFSRVQITHIAGLIKLSKNDVERKLSQMILDKKFHGILDQGEDVLIIFEEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KLV9-1", "uniprot_id": "PSD11_DROME", "id": "Q7KLV9-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "--MAGATLFERAQALSSVNR-EEQDSSLLNKLVRDQEG------AENDEERIRIKEQGILQQGELYKQEGKAKELADLIKVTRPFLSSISKAKAAKLVRSLVDMFLDMDAGTGIEVQLCKDCIEWAKQEKRTFLRQSLEARLIALYFDTALYTEALALGAQLLRELKKLDDKNLLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKVQGALDLQSGILHAADERDFKTAFSYFYEAFEGFDSVDSV----KALTSLKYMLLCKIMLGQSDDVNQLVSGKLAIT-YSGRDIDAMKSVAEASHKRSLADFQAALKEYKKELAEDVIVQAHLGTLYDTMLEQNLCRIIEPYSRVQVAHVAESIQLPMPQVEKKLSQMILDKKFSGILDQGEGVLIVFEETPVDKTYERVLETIQSMGKVVDTLYQKAKKLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12377-1", "uniprot_id": "RPN6_YEAST", "id": "Q12377-1", "name": "26S proteasome regulatory subunit RPN6", "aln": "-MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGASVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIEKFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALINDLLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLMSGILHCED-KDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLIDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSHFNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQGNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*: * . .: : . : :* . . *:: . :* .**: * * * :* :: :: .::*:*:.:::::*:: * :: . . :: :* ..**:** ***.**:::*. :* :*:::. * ::* * :**:*:**:*** **:::*****.** * **.*::*:**:***:**:****.: . **: ***:*. : :*:***:***:*:**.:..: : :* ******.****. ::*: ::..* * .* :*:*.:*:* ::*** **: **.:* ** * : :*: ***.:**.** ::***:. *:: *:: * * :** ********: * *:****:. * ::: . * **: ** : .:.**** *:.**. * ", "identical_positions": 155, "similar_positions": 145, "identity": "35.55%" }, { "cls_id": "homologset.agr.SGD:S000002256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NC0-1", "uniprot_id": "ZMAT2_HUMAN", "id": "Q96NC0-1", "name": "Zinc finger matrin-type protein 2", "aln": "MASGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQP-------VKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK-EKQKEKKRRAEEDLTFEED---DEMAAVMGFSGFGSTKKSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPW7-1", "uniprot_id": "ZMAT2_MOUSE", "id": "Q9CPW7-1", "name": "Zinc finger matrin-type protein 2", "aln": "MASGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQP-------VKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK-EKQKEKKRRAEEDLTFEED---DEMAAVMGFSGFGSTKKSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VZF0-1", "uniprot_id": "Q9VZF0_DROME", "id": "Q9VZF0-1", "name": "U1-type domain-containing protein", "aln": "MTMRPD----DHRRKWDKNEYEKLAAERLLNQVAPKEEEPVQ----------RENLKRRDYKVDLDSKLGKSVVINKNTPTSQSGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKVERSTVDQVKERFQQNKKKMEEKQKDYELERRLREAKEEEDRYKEHRK-EKRKERKRKAED-TDFESGGMPDDMAAIMGFSGFGGSKKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12368-1", "uniprot_id": "SNU23_YEAST", "id": "Q12368-1", "name": "23 kDa U4/U6.U5 small nuclear ribonucleoprotein component", "aln": "-MSNFG------RRTWDREEYAEQARSGYDDRSLKATLTPIELQALKSKYTNYDHLIKGSLKDLNKRKLTANTESLSSFKRGKKFGFYCDICNLTFKDTLQYIDHLNHKVHAIKFEN--LFDEPLIIDIRDNDDVPQEEFELCY--HNLIKDFVEVRSMETQSKRKRLLDTDVEKAKKVATKPSIESE---SKVSQMMGFSNFATSKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **.**::** : * . :. *:: : * : . * . ** . .. .: *:**::*: ..**:::::**:* * * :: .:.. : :::.. : ::::* ::: . : * :. * : * : :. *: ::. :*. ..:: :****.*. :** ", "identical_positions": 36, "similar_positions": 73, "identity": "17.14%" }, { "cls_id": "homologset.agr.SGD:S000002258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9T7-1", "uniprot_id": "GET3_RAT", "id": "G3V9T7-1", "name": "ATPase Get3", "aln": "MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGR--ESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE-EDNMLSMGKK----------MMQEAMSAFPGIDEAMSYAEVMRLVK------GMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPD--PEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSTQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54984-1", "uniprot_id": "GET3_MOUSE", "id": "O54984-1", "name": "ATPase GET3", "aln": "MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGR--ESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE-EDNMLSMGKK----------MMQEAMSAFPGIDEAMSYAEVMRLVK------GMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPD--PEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSTQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43681-1", "uniprot_id": "GET3_HUMAN", "id": "O43681-1", "name": "ATPase GET3", "aln": "MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGR--ESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE-EDNMLSMGKK----------MMQEAMSAFPGIDEAMSYAEVMRLVK------GMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPD--PEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQE5-1", "uniprot_id": "GET3_DANRE", "id": "Q6IQE5-1", "name": "ATPase GET3", "aln": "MAASVE------DEFEDAPDVEPLEPTLKNIIEQKSLKWIFVGGKGGVGKTTCSCSLAVQLAAVR--ESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE-EDNMLSMGKK----------MMQEAMSAFPGIDEAMSYAEVMRLVK------GMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCRIDTHNIIVNQLVFPD--NERPCKMCEARHKIQSKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSKQLLEPYSPPKK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JWD3-1", "uniprot_id": "ASNA_DROME", "id": "Q7JWD3-1", "name": "ATPase ASNA1 homolog", "aln": "----------------MADNLEPLEPSLQNLVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVR--ESVLIISTDPAHNISDAFDQKFTKVPTKVNGFDNLFAMEIDPNAGLNELPEEYFDGENEALRVSKG----------VMQEMINALPGIDEAMSYAEVMKLVK------GMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQFVSMLGMADVNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNIIVNQLLFLQN-SHDSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIRSFSENLMKPYNPKGEPKE--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12154-1", "uniprot_id": "GET3_YEAST", "id": "Q12154-1", "name": "ATPase GET3", "aln": "------------------MDLT-VEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALKDMNDMAVSRANNNGSDGQGDDLGSLLQGGALADLTGSIPGIDEALSFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITNKLGPMLN---SFMGAGNVD---ISGKLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAENDQEHNCKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELEDKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :**.* .:: . : ***************.*.*:*:*:: : :..*:********:****.:** * . **.* :** .*****. .: :: : .. :: .: : : .::******:*: ***: :* * .*..*:***********:: :* :.: * :: .:. ::.*::. .::* .::: :: **:: : : :**.:*: ***:****:**:********:*** . :*.:.******:* : . *. * :* *:* *****: :******:.*:** *:** :.: .** * : *.* ", "identical_positions": 137, "similar_positions": 113, "identity": "36.15%" }, { "cls_id": "homologset.agr.SGD:S000002259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z265-1", "uniprot_id": "CHK2_MOUSE", "id": "Q9Z265-1", "name": "Serine/threonine-protein kinase Chk2", "aln": "MKSHHQSHSSTSSKAHDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPE-----EPGPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFREMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIA---LSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPS-VETEIEILKKLNHPCIIKIKDVFDAED------YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQ----------------EEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQTS-SQKRPLELEVEGMPSTKRLSVCGAVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96017-1", "uniprot_id": "CHK2_HUMAN", "id": "O96017-1", "name": "Serine/threonine-protein kinase Chk2", "aln": "---MSRESDVEAQQSHGSSACSQPHGSVTQSQGSS------SQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIA---LSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALN-VETEIEILKKLNHPCIIKIKNFFDAED------YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ----------------EEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BC68-1", "uniprot_id": "A0A8M2BC68_DANRE", "id": "A0A8M2BC68-1", "name": "", "aln": "-----------MSEEAGPSGESQSQ-TQSQTQSQP------------ASSSSSAPTSSSQGSSSGSGTLSSVDTVPVQELQSIPEDEE-------EVQPQVWGRIIPLKQGFSVLNCTENQYSFGRDKRCDYSFSNSILKKSPYFNTYSKKHFRIFRDEN-----LVYLEDLSGNGTWVDDEKLGNGKQSLLSNNSVIA---LAEQKHQVFMFIDKMADDQANLPLEFSKKYHIARKIGTGVCGEVKLAIEKETFKKVALKTINKHDFPS----IGTATRN-AEREIEILKKIDHPCLIKTEDFYQTEDS-----YYIVLEYIEGGELFGRIKAKKKLEEDIAKLYFYQMLKAVEYLHNNGIIHRDLKPENVLLASH----------------DDICLIKITDFNQSKILEESSLMKTLCGTPTYVAPEVFTHASTVGYTKAVDYWSLGVLLFICLGGYPPFNTECTTMSVREQIINGEYRFIPSQWKNVSNEAKDLVKKLLVVDPQKRLSVEEALEHPWLKDDRMRQNANQLMN-----PGAANQPMRPEATRQKRKAHEGEGEPSSKRKPGP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61267-1", "uniprot_id": "LOK_DROME", "id": "O61267-1", "name": "Ovarian-specific serine/threonine-protein kinase Lok", "aln": "-----------MARDTQGTQGTQSQASNIWTQVES-------------------QPMEKIVWGRLYGKNIKIKSLGTSSKY----------------------RIIYTHSSFS-VDLNNDEFTAGRGEANDLILTLNDLP--EKILTRISKVHFIIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVIS---LSHPTYKAFVFKDLSPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDS-----VYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETN----------------DEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTP-AAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEPPTKRSRR----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39009-1", "uniprot_id": "DUN1_YEAST", "id": "P39009-1", "name": "DNA damage response protein kinase DUN1", "aln": "-------MSLSTKREHSGDVTDSSFKRQQRSNKPS----------SEYTCLGHLVNLIPGKEQKVEITNRNVTTIGRSRSCDVILSEP---------------DISTFHAEFHLLQMDVDNFQRNLINVIDKSRNGTFINGNRLVKKDYILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYKNDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQ------QNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKG---YTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFND--IQQQSSVSLELQRLQITDNKIPKTYSELSCL----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .: . . .: :: . : : * :: ::: . : : : . . . * .. : * :.. .::. : :: : . . * : . * : : :*:* . *: . : .* ::.*:* . . . * :*: .:.** ::. : *:*** : .*:*: :: :. * : .* * *: .::***:..* ***:**:*:** : :*::**. :*: : .. .****** *:****: . *. ** ** **:*: ** * **. . :** ...: : * .:.: . *:.::*:::*. * . ::.*. .*:.* : :: . : ", "identical_positions": 75, "similar_positions": 141, "identity": "12.98%" }, { "cls_id": "homologset.agr.SGD:S000002260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54747-1", "uniprot_id": "DPOD1_RAT", "id": "O54747-1", "name": "DNA polymerase delta catalytic subunit", "aln": "MDGKRRQ--------APSSGVPPKRACKGLWDED-------------EPS--QFEENLALLEEIEAENRLQEA-EEELQLPPEGIVGGQFSTADIDPRWLRPTPLALDPSTEPLIFQQLEIDHYVGTSPPLPEGPPASRNSVPILRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGAEHLSELQRELNAAISRDQRGGKELSGPAVLAIELCSRESMFGYHGHGPSPFLRITLALPRLMAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKYVRR----AEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWATFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMREGLLMPVVKTEGG-EDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLG----LKPDEFIKTPTGDEFVKASVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSPNSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVETKYTLENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDRMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNSCIGCRSVIDH---QGAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFGPPGPEAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52431-1", "uniprot_id": "DPOD1_MOUSE", "id": "P52431-1", "name": "DNA polymerase delta catalytic subunit", "aln": "MDCKRRQ--------GPGPGVPPKRARGHLWDED-------------EPSPSQFEANLALLEEIEAENRLQEA-EEELQLPPEGTVGGQFSTADIDPRWRRPTLRALDPSTEPLIFQQLEIDHYVGSAPPLPEGPLPSRNSVPILRAFGVTDEGFSVCCHIQGFAPYFYTPAPPGFGAEHLSELQQELNAAISRDQRGGKELSGPAVLAIELCSRESMFGYHGHGPSPFLRITLALPRLMAPARRLLEQGVRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKYVRR----AEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVISMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMPVVKTEGS-EDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLG----LKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVIDH---QGAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFGPPGPEAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28340-1", "uniprot_id": "DPOD1_HUMAN", "id": "P28340-1", "name": "DNA polymerase delta catalytic subunit", "aln": "MDGKRRP--------GPGPGVPPKRARGGLWDDDD------------APRPSQFEEDLALMEEMEAEHRLQEQEEEELQSVLEGVADGQVPPSAIDPRWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRESMFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALR----LKEKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGG-EDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLG----LTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLSH---QGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFGPPGPEAW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54358-1", "uniprot_id": "DPOD1_DROME", "id": "P54358-1", "name": "DNA polymerase delta catalytic subunit", "aln": "MDGKRKF--------NGTSNGHAKKPRNPDDDEE-----------------MGFEAELAAFENSEDMD--------QTLLMGDGPEN-----QTTSERWSRPPPPELDPSKHNLEFQQLDVENYLG--QPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEKLNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTSQGSDEQYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFT-RPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKEL--AKTDYAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDN-AESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRVLRFG---LAEW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15436-1", "uniprot_id": "DPOD_YEAST", "id": "P15436-1", "name": "DNA polymerase delta catalytic subunit", "aln": "MSEKRSLPMVDVKIDDEDTPQLEKKIKRQSIDHGVGSEPVSTIEIIPSDSFRKYNSQGFKAKDTDLMGTQLESTFEQELSQMEHDMADQ-EEHDLSSFERKKLPTDFDPSLYDISFQQIDAEQSVLN-------GIKDENTSTVVRFFGVTSEGHSVLCNVTGFKNYLYVPAPNSSDANDQEQINKFVHYLN--------ETFDHAIDSIEVVSKQSIWGYSGDTKLPFWKIYVTYPHMVNKLRTAFERGHLSFNSWFSNGTTTYDNIAYTLRLMVDCGIVGMSWITLPKGKYSMIE---PNNRVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEPEYDPVIQIANVVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISDLQNGDSETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFRKCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCYTTLCNKATVERLN---LKIDEDYVITPNGDYFVTTKRRRGILPIILDELISARKRAKKDLRDEKDPFKRDVLNGRQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWT-NPDKFDKLDQKGLASVRRDSCSLVSIVMNKVLKKILIERNVDGALAFVRETINDILHNRVDISKLIISKTL---APNYTNPQPHAVLAERMKRRE-GVGPNVGDRVDYVIIGGND--KLYNRAEDPLFVLENNIQVDSRYYLTNQLQNPIISIVAPIIGDKQANGMFVV---KSIKINTGSQKGGLMSFIKKVEACKSCKGPLRKG--EGPLCSNCLARSGELYIKALYDVRDLEEKYSRLWTQCQRCAGNLHSEVLCSNKNCDIFYMRVKVKKELQEKVEQLSKW--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ** . *: *. :: : :: : : : . : :**. : ***:: :: : . .. .::* **** ** ** *:: ** *:* ** .. .::: :. : *: :*: .: .: ** *. : :* :: *::: ::: . . *: : :*:*** .:** .*: ** *:: : **:*..: : .::* .** *.: **:*::********* *:***.: ******..: * :**:* .:**. *:** *: : .: * ::*. * *: :***:: *** ***:***:.** *** * ::**: : . *::. :.*: * *:.: :.: **: :*:* .: *::*********** *** ******::***:*****:.:******:******:*****:*:**.:** *********: **:****:**:***:*:. . ::* ::.. ::* ******* :*** **:**** ***************** .: ::* :: ** .: **.:. *:*:** **:.*::****** :* *.**::*.**:*******:*.********* ******* ** ***.:** ** ** *: :* ***. .* *:******** .**.. : .:* ** ***. ** * **.*****.*:*****.******* :: ..* .*::* **: :****...**: ::. *:::*::*: :**:*..::.* *:* **:***:*:*:* * .:*: *.*. ** :*::*: * .*.:**** *** .. . * ::****:***:.: :*: *** :** :*:: *. **:*: *:.::: . : .: *** .* .: .* .*: : : :. :* * .* .*** * : . *** :*****:**** .**.:*:*:.::* ***** **: :*::: . : :: ", "identical_positions": 431, "similar_positions": 315, "identity": "37.84%" }, { "cls_id": "homologset.agr.SGD:S000002261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF39-1", "uniprot_id": "D3ZF39_RAT", "id": "D3ZF39-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNVNDLRQRLSAAGQQHLLQFWSELSEAQQGELYMELQAMN----FEELNSFFQKAVGEFD-RSSHQEKVDARMEPVPRQVLGSATR-DQDQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVTYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKQYGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGKVILEEK-NKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPYVDSQ-GHLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKDFHAPLIIDENGVHELVKNGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YN5-1", "uniprot_id": "UAP1_MOUSE", "id": "Q91YN5-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNVNDLKQRLSQAGQEHLLQFWNELSEAQQVELYMELQAMN----FEELNSFFRKAIGEFD-RSSHQEKVDARMEPVPRQVLGSATR-DQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGKIILEEK-NKVSMAPDGNGGLYRALAAQNIVEDMEQRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQRRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPYVDSQ-GYFIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSEAITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKEFHAPLIIDENGVHELVKNGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16222-1", "uniprot_id": "UAP1_HUMAN", "id": "Q16222-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMN----FEELNFFFQKAIEGFN-QSSHQKNVDARMEPVPREVLGSATR-DQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEK-NKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYVDTQ-GQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4INK2-1", "uniprot_id": "A0A0R4INK2_DANRE", "id": "A0A0R4INK2-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MDIHKLAERLAKAGQSHVIQFWDQLSPEEQGEMSLDLESMN----FLEINNFFKSAMKTSG-QSS-QEKVDTRMEPVPRDVLGSVTR-DRECLKEWEKEGLRCIAENKVAVLLLAGGQGTRLGVSFPKGMYDVGLPSHKTLFQIQAERIRKLEQLAEKQHSRKCCIPWYIMTSGRTMDMTKDFFIQHKYFGLKEENVVFFQQGMLPAMDFNGKIILEGK-CKLAMAPDGNGGLYRALGTQNIVKDMETRGISYIHVYCVDNILVKVADPAFIGFCTLKGADCGAKVVEKTNPTEAVGVVCKVDGRYQVVEYSEITLATAEKRSTDGRLMFNAGNIANHFFTLTFLREIVRTHEPQLQHHVAQKKIPYVNTE-GQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQDGKDNPTTARHALMSLHHRWILNAGGHFVDENGTHIPAIPRAGPAG---TVTPEVSQNLKDGTDLPIKCEISPLVSYGGEGLEHLVNEKVFQPTLIINESGVHELVKNGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TW96-1", "uniprot_id": "UAP1L_MOUSE", "id": "Q3TW96-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "aln": "-------------------------------------MDSERDVRAQLQRAGQDHLLRFYADLAPEARAALLAELASLE----ADALREHCQRAAAAGALAPGPLPDLAARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERK-DKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEE-GNLVKPLRPNGIKMEKFVFDVFQFA--KNFVAFEVCREEEFSPLKNDDTAD-RDNPSTCRRALLAQHYRWALQAGARFLDVHGVQLTEQSGMLPNG-----------------DPPAICEISPLVSYSGEGLEMYLQGRQLQSPFILDEDQARLLRPQDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KQV9-1", "uniprot_id": "UAP1L_HUMAN", "id": "Q3KQV9-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "aln": "-------------------------------------MASEQDVRARLQRAGQEHLLRFWAELAPEPRAALLAELALLE----PEALREHCRRAAEACARPHGPPPDLAARLRPLPPERVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYRVGLPSRKTLYQLQAERIRRVEQLAGERHGTRCTVPWYVMTSEFTLGPTAEFFREHNFFHLDPANVVMFEQRLLPAVTFDGKVILERK-DKVAMAPDGNGGLYCALEDHKILEDMERRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETAQLRASDGSLLYNAGNICNHFFTRGFLKAVTREFEPLLKPHVAVKKVPYVDEE-GNLVKPLKPNGIKMEKFVFDVFRFA--KNFAALEVLREEEFSPLKNAEPAD-RDSPRTARQALLTQHYRWALRAGARFLDAHGAWLPELPSLPPNG-----------------DPPAICEISPLVSYSGEGLEVYLQGREFQSPLILDEDQAREPQLQES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWD4-1", "uniprot_id": "UAP1L_DANRE", "id": "Q7ZWD4-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "aln": "--------------------------------------MSFEEAKAKLEAAGQTHVLQFWDELSAEERGTFLEEISQLQ----PDELVEHCREAAASASRHSSADGRLDARMQPVPPEFIGSVRKSDRETLQKWENEGLLQISQDRVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIQKVQELANVRHGCRCTVPWYIMTSEFTLGPTEKFFKDNKYFGLCPSNVVMFEQRMIPAVGFDGKIILEKK-NKIAMAPDGNGGLYRSLVDNKILADMERRNVEFLHVYCVDNILVKMADPVFIGFCVTNGADCGAKVVEKAYPAEPVGVVCRVDGVYQVIEYSEIQPETAELRGSGGELVFSAGNICNHFFTRSFLRDVAEKFESKLKQHVAIKKVPFVDGE-GNLVKPTKPNGIKMEKFVFDVFQFS--KKFVAFEVLREEEFSPLKNADGAP-LDTPTTARRSLLAQHYRWILAAGGSFLDEQNKPFTPKHSTAQIE-----------------DPPAVCEISPLVSYFGEGLEMLLNQKNLKSPFILDENEAKNLVHTV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0Z0-1", "uniprot_id": "Q9Y0Z0_DROME", "id": "Q9Y0Z0-1", "name": "UDP-N-acetylglucosamine diphosphorylase", "aln": "MGRSNFSSHHQQTHVRRHRNAGGATSKSPNAAKTSPTMTDYLSLHSRLAQVGQEHLLKFWPELTNDERIDLVRDIEELN----LDEIKLYFDRATVSMN---ENGIKLDDRLQPLPEGKLISIARAPLEKLDAYRDEGLLQISNGHVAVLLMAGGQGTRLGFDHPKGMYDVGLQSRKTLFRIQAERILKLEELAQEANGKRGHITWYIMTSEHTVQPTYDYFVANNFFGLKAENVLLFEQGSLPCFEYDGRIILDEK-HRVARAPDGNGGIYRAMKRQGILDDMQKRGVLYLHAHSVDNILIKVADPVFIGYCVQEKADCAAKVVEKAAPNEAVGVVAIVDGKYQVVEYSEISAKTAEMRNSDGRLTFSAGNICNHFFSSNFLQKIGSTYEQELKLHVAKKKIPFVDNA-GKRLTPDKPNGIKIEKFVFDVFEFA--QKFVAMEVPRDEEFSALKNSDAAG-KDCPSTARSDLHRLHKKYIEGAGGIVHG------------------------------------EVCEISPFVTYAGENLASHVEGKSFTSPVYLRDS--RDPLHGHL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43123-1", "uniprot_id": "UAP1_YEAST", "id": "P43123-1", "name": "UDP-N-acetylglucosamine pyrophosphorylase", "aln": "----------------------------------------MTDTKQLFIEAGQSQLFHNWESLSRKDQEELLSNLEQISSKRSPAKLLEDCQNAIKFSL--ANSSKDTGVEISPLPPTSYESLIGNSKKENEYWR-LGLEAIGKGEVAVILMAGGQGTRLGSSQPKGCYDIGLPSKKSLFQIQAEKLIRLQDMVKDK---KVEIPWYIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQSPDGNGGLYRAIKENKLNEDFDRRGIKHVYMYCVDNVLSKIADPVFIGFAIKHGFELATKAVRKRDAHESVGLIATKNEKPCVIEYSEISNELAEAKDKDGLLKLRAGNIVNHYYLVDLLKRDLDQWCENMPYHIAKKKIPAYDSVTGKYTKPTEPNGIKLEQFIFDVFDTVPLNKFGCLEVDRCKEFSPLKNGPGSK-NDNPETSRLAYLKLGTSWLEDAGAIVKDG-----------------------------------VLVEVSSKLSYAGENLSQFKG-KVFDRSGIVLEK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .** :::: : .* : : :: :. : * .: *:* . :. *: *. ..***:*:********* *** * :** * *:*:::***:: :::::. : :.**:*** * * :* :.:* * :: :*:* :*.. *: :* . .:: :******:* :: : : *:. *.: :: :.***:* ::*** ***:. . : .:*.*.* . *.**::. : *:***** * .* * **** **:: :* : *:* **:* : * .* .*****:*:*:**:* ::* ** * .***.*** * * *.* : **. . . *:*. ::* **.* : : . : :. ", "identical_positions": 128, "similar_positions": 128, "identity": "22.46%" }, { "cls_id": "homologset.agr.SGD:S000002262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7F3-1", "uniprot_id": "OSGL1_RAT", "id": "Q4V7F3-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "MLMLSKTAG-AIPRPPRSNVRGFIRRFNVQPRALFHHKLVLGIETSCDDTAAAVVDETGNVLGEALHS---QTEVHLKTGGIVPPVAQQLHRENIQRIVEEALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSVQLVNQFKKPFIPIHHMEAHALTIRLTH---KVGFPFLVLLISGGHCLLALVQSVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKEG-NRFHFTINPPMQNAKN----CDFSFTGLQHVTDKLITHKEKEEGIEKGQILSSAADIAAAVQHATACHLAKRTHRAILFCQQ--KNLLSPANAVLVVSGGVASNLYIRRALEIVANATQCTLLC----PPPRLCTDNGIMIAWNGIERLRAGL--GILHDVEDIRYEPKCPLGIDISREVAEAAIKVPRLKMTL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PEB4-1", "uniprot_id": "OSGL1_MOUSE", "id": "Q6PEB4-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "MLMLRRTAG-AIPKPPKSKVYGFLRRFSVHPRTLSCHKLVLGIETSCDDTGAAVVDETGNVLGEALHS---QTQVHLKTGGIVPPVAQQLHRENIQRIVEETLSACRITPSDLSAIATTIKPGLALSLGVGLSFSLQLVNQFKKPFIPIHHMEAHALTIRLTN---KVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEQLAKDG-NRFHFTINPPMQNAKN----CDFSFTGLQHITDKLITHKEKEEGIEKGQILSSAADIAAAVQHATACHLAKRTHRAILFCKQ--KNLLSPANAVLVVSGGVASNLYIRKALEIVANATQCTLLC----PPPRLCTDNGIMIAWNGIERLRAGL--GVLHDVEDIRYEPKCPLGVDISREVAEAAIKVPRLKMAL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4B0-1", "uniprot_id": "OSGL1_HUMAN", "id": "Q9H4B0-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "MLILTKTAG-VFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNVLGEAIHS---QTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTN---KVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQG-NRFHFDIKPPLHHAKN----CDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQ--RDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLC----PPPRLCTDNGIMIAWNGIERLRAGL--GILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32LQ3-1", "uniprot_id": "OSGL1_DANRE", "id": "Q32LQ3-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "-MFQSCLPG-ALRSWSRG-----VFSTSTRP------RLVLGIETSCDETGAAVLDETGRILGESLHS---QKETHLKTGGIIPLVAQRLHRENISRVVQEALNRSAIEPSELTAVATTVKPGLALSLGIGLDYSLKFVRQHQKPFIPIHHMEAHALTVRMLH---PLDFPFLVLLVSGGHSLLALAKGIDEFLLLGQTLDEAAGDTLDKIARRLSLRNHPECGTLSGGQAIERLAKEG-DRLAFHFISPMGQNYD----CNFSFAGLRTQITGAINKKEKEEGVEAGQFLSCVKDIAAASQHTVASHLAKRTHRAILFCKS--KGLLPEQNPTLIVSGGVASNEYIRQILKIITDATGLHLLC----PPSKFCTDNGVMIAWNGIERLKQGK--GILSYSEEVSYEPKAPLGLDITSEVKEAAIKVPKLKLRTNS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWD6-1", "uniprot_id": "OSGP2_DROME", "id": "Q9VWD6-1", "name": "Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "MHALRNFAGNGIAN---------VFGCGIRRR----LSYVLGIETSCDDTGIAIVDTTGRVIANVLES---QQEFHTRYGGIIPPRAQDLHRARIESAYQRCMEAAQLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARMEHP-EQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEYRLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRN----CNFSFAGIKNNSFRAIRARERAERTPPDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDAIYANIEHLAAQYGCRSFR----PSKRYCSDNGVMIAWHGVEQLLQDKEASTRYDYDSIDIQGSAGFAESHEEAVAAAAIKCKWIQPLV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43122-1", "uniprot_id": "QRI7_YEAST", "id": "P43122-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "aln": "MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKG-----YKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREG-IDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREME--KFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELP--EREIRSIAYQVQESVFDHIINKLKHVLKSQPE-----KFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLR---LVSDLDICPIR-----QWPLNDLLSVDGWRTDQL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **.******:* :::* .. . : : : ***:* *: *: .* :. : . . : :..* **:. ** *: :: :. :**:: :*** .* * *: :**: ** **** :.: .. . :* .::* * *: :** .*.* : . : *:: : : : *: : . .***:.: : : * .:. .: *: :: ::.: :: ****:.* : :: : *. *:**.:**.* *:* : . : . : : ", "identical_positions": 68, "similar_positions": 104, "identity": "15.6%" }, { "cls_id": "homologset.agr.SGD:S000002263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9K8-1", "uniprot_id": "D3Z9K8_RAT", "id": "D3Z9K8-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSRSPLA--------RRGAAPE-----RREAAERPSLEDTEPSDSGDELMD-----PACLEAEYDQGLCRQIRHQYRALINSVQQNREDILN-AGDKLTEVLEEANTLFNEVSR-AREAV------LDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAE-EFIRDEDRTDIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRTDRPRQPRMIEEQRAMPAQLKCMEES-HQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPV-INEESEGIDQNIQFRSQ-------GIIALSYHDWEEIVKTFEISEPVISLSQSQQRLSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3XA30-1", "uniprot_id": "G3XA30_MOUSE", "id": "G3XA30-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSRSPLA--------RRGAAPE-----RREAAERPSLEDSDLSDSGDELMD-----PACLEAEYDQGLCRQIRHQYRALINSVQQNREDILN-AGDKLTEVLEEANTLFNEVSR-AREAV------LDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAQ-EVIRDEDRADIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRSDRPRQPRMIEEQRAMPAQLKCMEES-HQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPV-INEESEGIDHNIQIRSQ-------GIIALSYHDWEEIVKTFEISEPVIPLSQSQQRLSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXX6-1", "uniprot_id": "NSE4A_HUMAN", "id": "Q9NXX6-1", "name": "Non-structural maintenance of chromosomes element 4 homolog A", "aln": "MSGDSSGRGPEGRGRGRDPHRDRTRSRSRSRSPLSP-----RSRRGSARE-----RREAPERPSLEDTEPSDSGDEMMD-----PASLEAEADQGLCRQIRHQYRALINSVQQNREDILN-AGDKLTEVLEEANTLFNEVSR-AREAV------LDAHFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAE-ELIRDEDSPDFEFIVYDSWKITGRTAENTFNKTHTFHFLLGSIYGECPVPKPRVDRPRKVPVIQEERAMPAQLRRMEES-HQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPVIEPVSINEENEGFEHNTQVRNQ-------GIIALSYRDWEEIVKTFEISEPVITPSQRQQKPSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V124-1", "uniprot_id": "EID3_MOUSE", "id": "Q3V124-1", "name": "EP300-interacting inhibitor of differentiation 3", "aln": "MSKEKCSL-TGGKEKRGELVRSLAWQHLVKQEEE------EAVKKEEKEE-----GEDEEEEGSDSSSDDPNPEPPCMH-----PDLLELVVDREKCRKIRRQYRQLIYTVQQNREDIVNTASDTLSEALEEANVLFDGVSR-TREAA------LDAQFLVLASDLGKEKAKQLNTDMNFFNPIAFCDLLLLFVGFNWVEEECKEFSDCDDS----IVLSFWGMLHEEATSWMLQAETFHFIFGSFKAERSARKPRLGCHKRACKMEGSGDMPTKLRRLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVSQVDDESDSYSYCRKQ-------GVISLSLQDWKNIVSTFEISEAMIKN-SY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LFN0-1", "uniprot_id": "A0ABK0LFN0_RAT", "id": "A0ABK0LFN0-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "MSEEKCSL-TGGEEKGEELARSLAWQHLVKQAEEDDDDDEEALKKEEEEEEEEEEDEEEEEEGPDSSSDDLSPEAPCMH-----PDLLELAVDREKCRSIRRQYRQLIYTVQQNREDIVNTASDSLTEALEEANVLFDGVSR-TREAA------LDAQFLVLASDLGKEKAKQLNSDMSFFNHVAFCELLLVFVGLNWMEEECEELSECDES----IALSFWNMLHKEATAWMLQAETFHFIFGSFKAERSARKPRQEHHKRACKMEGNGDMPTKLRKLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVNQVDEENDSCSYCRKQ-------GVISLSLQDWKNIVSTFEISEAMIKN-SY------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N140-1", "uniprot_id": "EID3_HUMAN", "id": "Q8N140-1", "name": "EP300-interacting inhibitor of differentiation 3", "aln": "MKMDVSVR-AAG------------------------------------------------------CSDDLSSGEADVD-----PKLLELTADEEKCRSIRRQYRQLMYCVRQNREDIVSSANNSLTEALEEANVLFDGVSR-TREAA------LDARFLVMASDLGKEKAKQLNSDMNFFNQLAFCDFLFLFVGLNWMEGDPDKLSDCDDS----IALSFWKAIEKEATSWMVKAETFHFVFGSFKLERSAPKPRLEHQKKVRKMEENGNMPTKLQKLDLSSYPEATEKNVERILGLLQTYFRKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIVRDGFARIRLDEDRLPILEPMNVNQMGEGNDSSCHGRKQ-------GVISLTLQEWKNIVAAFEISEAMITYSSY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKV4-1", "uniprot_id": "Q9VKV4_DROME", "id": "Q9VKV4-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "-----------------------------------------------------------------------------MD-----SSESQSQMDDQDARILRLQN--LIEKNIEIEQQIENNTIGESITAIEEIIQTANDISKGHEDRR------TNSTELVLDTELLRRNFEVVGKAIQHNTNVTDRMVATAINDLVFKESE-----------------EDWDALCSLAIQFGRPLFTNDSMLPFIDVTPKVVVQKQRAPRKTKSQVDEK-RPEKSDQLERK---DEGAASVTHMLKQIRQIYRDGNQEPIPYFKLICNPNNFMDTVQNALQLSFLVKENYISIENGEDGLPLVRVVNSKSVEG------NAPSQ-------AICSIDVTFCEKMVKHYNLHEPMLKRLPVSEK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43124-1", "uniprot_id": "NSE4_YEAST", "id": "P43124-1", "name": "Non-structural maintenance of chromosome element 4", "aln": "MSSTVISRKRRNSTVTEPDSSGETRKQKKSRSDEKSSSSKDGDPQLEFKVLQGYRDLESEMHKGRAQVTRTGDIGVAMDNLNAVDSLFNKVIGIKNNGLFAHDARAMVSISELAQISVRNLKFDDSRSMVNLENIVNSLKRYMLKEHFKLNNIAENRNDLTLAADEQSAADQQEESDGDIDRTPDDNHTDKATSSFKATSMRHSYLQQFSHYN--EFSQFNWFRIGALYNTISKNAPITDHLMGPLSIEKKPRVLTQRRRNNDQVGEKITAEKITQHSLNST-QQETTPEQVKKCFKKLSKKLG--PEGSINLFKFIIDPNSFSRSIENLFYTSFLIKEGKLLMEHDEEGLPTIKIKQSISHTDSRSKEIERQRRRAAHQNHIIFQMDMPTWRKLIKKYNITSPFLD----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . : : :: . .: . . :: . .: : *.: :: : . . .. . * . :: : .. :: : .* : : : : .: *.:: :*:.* :::* : **::::. :. .:: ** :. . : : : .::: ::: ...: ", "identical_positions": 11, "similar_positions": 82, "identity": "2.64%" }, { "cls_id": "homologset.agr.SGD:S000002266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51952-1", "uniprot_id": "CDK7_RAT", "id": "P51952-1", "name": "Cyclin-dependent kinase 7", "aln": "--------ANRNEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIP---LQHIFIAAGDDLLELIQGLFLFNPCTRITASQALRTKYFSNRPGPTPGCQLPRPNCPVEALKEQSNPAM-----ATKRKRAEALEQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03147-1", "uniprot_id": "CDK7_MOUSE", "id": "Q03147-1", "name": "Cyclin-dependent kinase 7", "aln": "MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGVP---LQHIFIAAGDDLLELIQGLFLFNPCTRTTASQALKTKYFSNRPGPTPGCQLPRPNCPVEALKEPANPTV-----ATKRKRAEALEQG---ILPKKLIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50613-1", "uniprot_id": "CDK7_HUMAN", "id": "P50613-1", "name": "Cyclin-dependent kinase 7", "aln": "MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIP---LHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPAL-----AIKRKRTEALEQG---GLPKKLIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24216-1", "uniprot_id": "Q24216_DROME", "id": "Q24216-1", "name": "Cyclin-dependent kinase 7", "aln": "MLPNANDKTERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGTP---LDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLPMP-SAILAAKEGANPQTGDTKPALKRKLVETTVRGNGLAQKKRLQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06242-1", "uniprot_id": "KIN28_YEAST", "id": "P06242-1", "name": "Serine/threonine-protein kinase KIN28", "aln": "MKVN-----MEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKT---SEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP-------------------SDPSS------IKIRN------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . :*** :*.** . : *.: :*:*:** .: :**:: :*:**:* ***:.* *:* *:* * .*:.**::*: *****:***:.:::* :.***: :***:*: : * ::************.. :* :*:.*****::: :*: * :*******:*******: * .:*:*:** *:***:**:*::**:.*:**: * :*****: :**.:..: * :: :* . * : * **.: :.:: :: :** * :. :.* ** : * * ::* * : ", "identical_positions": 124, "similar_positions": 102, "identity": "34.73%" }, { "cls_id": "homologset.agr.SGD:S000002267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQV8-1", "uniprot_id": "A0A8I5ZQV8_RAT", "id": "A0A8I5ZQV8-1", "name": "", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPPRIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEISFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHYSIYRGLHHHANIMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRSAPAQSKDSAIPTLESVVFGVNYTKQLSPDGCTFLIAEPFLQHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLDLAKASMQVLYERLLRRAQPRTQNDTCLEAMDTEARLTELCEEVKKVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEELRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQISEASKVDKHETEESSVAGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPETTKKLIKQNSKDSVVLVSYKCLKNTASSDLTKCFEGNPSYSQKEGLDPTMCRDNFDPKTYIRQPSQKEASSLSADTDRAEHKSPDTETMHPDQSALLNSGSLNLCANLSISGKLGISQDDSDIPDTEHKLASRSPSNDCLDCQTAPSSGVRTLEVKPSSEESFSEEKVTVKIGPWTELQEDELFVNNLLPDFEALDSNDKSKSIDLPLEKDAL-QEAKCRCTEESLTKFRSNLPAPSTKEYHVVVSGDTIKLPDSNAAYASSRFSDSGVESEPSSFATHPNPEIAFETLQGPGPCNNERLLPQLLMKPDHNVKLSLGSHCTESTSALSEIQQSSLTSINSLPSDDELSPDDDCKRCAVADCQLSDSKTVLHPGTTSLPKWDDTKKSSVILQQQCVVFSGHLDNDTLAMHS-----LDLSSEDPLQLILSGEDASSGVRS--------HWGSKPHLDTVFTGSQSHSTSSINSVET-----------VPTLNSKLICLGSPCVVSGSVCTDAELSEDR-TVEGKSSEPLNHKQICSEGPVVESHPLSTGDDSLS-SSTDVVKQGLVEDYFGSQSN--TDVSDACAVTYHSLVSSQ-ETCDKGIGDLQQEQGKEGMQD--DQEMVQNGYHEETDFPATGGAV--------------SVHCVRADELGGQRHELSENLSSD--YLRAAVTVPAVCTSACLSFPSAPRESPC-VKYSSRSKVDAITKQPS-SISYNFTSSTSWYENSPKPQIHAFLQAKEELK-QLKLPGFMYSDVPLLASSAPYFSMEEEE-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NS59-1", "uniprot_id": "F135A_MOUSE", "id": "Q6NS59-1", "name": "Protein FAM135A", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPARIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEISFLLSLGLHFTDGDYSADDLNALQLISSRTLKLHYSICRGLHHHANVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQSKDSAIPTLESVVFGINYTKQLSPDGCSFLIAESFLHHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLD--------------------------LEEMDVEARLTELCEEVKKVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEDLRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQISEASKTDKHETEESSVVGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPENTKKLIKQNSKDSVVLVSYKCLKTTASSDFTKCLEGSPSHSQKEGLDPTLCAGNFDPKTYTRQPSQKEASSLSANTDRSEHKSPDTENMQPDQFELLNSGSLNLCANLSISGKLAISQDNSDIPDTEHNLASTSSSNDCHDYQTTPSSGVRTLEVKSSSKESFNGEKITVKIGPWTELQEAELFVDNLLPDFEALDSNDKPKSIDIPLERDAL-QETKCHSTEESLTKFRSNLPAPSTKEYHVAVSSDTIKLPDTNATYASSRFSDSGVESEPSSFATHPNPEIAFETLQGPGPCNNERLFPQLLMKPDHNVKFSLGSHCTESTSALSEIQ-SSLTSINSLPSDDELSPDDNCKKSAVPDCHLSDSKTVFNLGTMDLPKCDDTKKSSIILQQQSVVFSGHLDNDTLAMHS-----LDLSTEDPLRLVFLDEDASSGVRS--------SWGSKPHLDAPFTGPQSQGTSSNNSTES-----------VPTLNSKLICLGSPCVVSGSVCTDAGLSADR-TVEGKSGEPLNHKQVCSAAPVVESDPLS--------SSTDVVKQGLVENYFGSQST--TDVSDACAITCHSPVSSQ-ETCDKGISDLQQEQGKEEEEE--DQEMVQNGYHEETDFSATDGTV--------------SVHYISGNELGEGRHEQSEKLSSN--YLSAGVTVPAVCTSGCLSFPSALRESPC-VKYSSRSKVDAITKQPS-SISYNFSSSTSWYENSPKPQIHAFLQAKEELK-QLRLPGFMYSDVPLLASSAPYFSMDEED-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2D6-1", "uniprot_id": "F135A_HUMAN", "id": "Q9P2D6-1", "name": "Protein FAM135A", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPSRIPHRVEASLLHATGMTLAFPASVHDSLICSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEMNFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHFSPHRGLHHHVNVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQNKDSVIPTLESVVFGINYTKQLSPDGCSFIIADSFLHHAYRFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLE--------------------------LEEMDVEARLTELCEEVKKIENPDELAELINMNLAQLCSLLMALWGQFLEVITLHEELRILLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVTEDLDAPWMGIQNLQRSESSKMDKYETEESSVAGLSSPELKVRPAGASSIWYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKSENTKKLIKQNSKDSVVLVGYKCLKSTASNDLIKCFEGNPSHSQKEGLDPTICGYNFDPKTYMRQTSQKEASCLPTNTERTEQKSPDIENVQPDQFDPLNSGNLNLCANLSISGKLDISQDDSEITQMEHNLASRRSSDDCHDHQTTPSLGVRTIEIKPSNKDPFSGENITVKLGPWTELRQEEILVDNLLPNFESLESNGKSKSIEITFEKEAL-QEAKCLSIGESLTKLRSNLPAPSTKEYHVVVSGDTIKLPDISATYASSRFSDSGVESEPSSFATHPNTDLVFETVQGQGPCNSERLFPQLLMKPDYNVKFSLGNHCTESTSAISEIQ-SSLTSINSLPSDDELSPDENSKKSVVPECHLNDSKTVLNLGTTDLPKCDDTKKSSITLQQQSVVFSGNLDNETVAIHS-----LNSSIKDPLQFVFSDEETSSDVKS--------SCSSKPNLDTMCKGFQSPDKS-NNSTGT-----------AITLNSKLICLGTPCVISGSISSNTDVSEDR-TMK-KNSDVLNLTQMYSEIPTVESETHLGTSDPFS-ASTDIVKQGLVENYFGSQSS--TDISDTCAVSYSNALSPQKETSEKEISNLQQEQDKEDEEEEQDQQMVQNGYYEETDYSALDGTI--------------NAHYTSRDELMEERLTKSEKINSD--YLRDGINMPTVCTSGCLSFPSAPRESPCNVKYSSKSKFDAITKQPS-STSYNFTSSISWYESSPKPQIQAFLQAKEELK-LLKLPGFMYSEVPLLASSVPYFSVEEED-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKDCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAI6-1", "uniprot_id": "F135B_MOUSE", "id": "Q9DAI6-1", "name": "Protein FAM135B", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESSSLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHFTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTME--------------------------LEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKE-KNLINQN----------------SSSRKDIPLSTTEAPQLGSDEDVTRR-------PEVQENVSTWNPID------------VCSESQVYLTIG--EFQNRAG---------IPEDECWTGPRPDAVKDSLTDTDIC-SRSPGPDEGQTPALTYID---------VQSSNKY--CPRAELVQGINVQHEHRSSRESYGIVKTVPSK-------------------VVAGTSQNNSTSLNQTAALELRTLGRGVNQDGKPVLLSLKLTPAEP-CDPPSTALREALDTKPSQPD-HAEEPEDLSALSGVIKR-------SASIISDSGIESEPSSVAWSEARSRALELP-------SDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSGIQASLSSISSLPFEEEER-------------ELALNKLTKSVSAPQISSPEESAEGADTI-KNTAGFSEDLDPS-----------SKENSPPRHTSLSYGGSRVQDVR-----------AGHSLADIALDSDRPQGPGYMDIPN---------------DKGNHPELQEPCCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAK-GKPEELS-MSKCVLSNNSISEVRAASHHRVPEISCSPAVEAVNLNSTG--VQNSSLSVNDTMTLNRRHNASLEAKHEAGTVCPTVTHTIASQVS-------------RNQELKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSK-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZ91-1", "uniprot_id": "F1LZ91_RAT", "id": "F1LZ91-1", "name": "", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESSSLHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHYTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTSEGSFYVPSENCIQHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTME--------------------------LEVLAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFEVPVTSPAIMKLKGKE-KSVINQK----------------SSSRKEAPLSTTEAPELGSDEDVIQC-------PEMEENVSTQNPMD------------VCSESQVYLSIG--EFQNRAG---------IPEDECWTGPRPDAVKDSLTDVDIC-RRSPGPEEGHTPALTYID---------VESSNKN--YPRAEPVLGLNVQHEPRGSRDSYGIVKTMPSK-------------------VLAGISQNNSISVNQTAALELRTLGRGVGQEGKPVLLSLKLTPAEP-CDPLSTGLREALDTKPSLPD-PGEEPEDLSVLSGVIKR-------SASIISDSGIESEPSSVAWSEARSRALEIP-------SDRDILHQVVRRHAHHRNSLEGGHTESNTSLPSAIQASLSSISSLPFEDEER-------------ELALTKLTKSVSAPQISSPEDTAEDSDTI-KNTAGFSEDLDLS-----------SKDNSSSRYSSPSYSGSRVQDVR-----------AGHSLADIAVASDRPQGPGYMDIHK---------------GNENHPDLQGPCCLDAMAENIPHVETKGLNLKIPCTTVLENPKTRSFHRTAVETAK-GKAKELS-LSKHMLSNNSISEVRAASHHRVPEISCAPAVGAGHLHSTG--VQNGSLSVNDTMTLNRRHNASPEAKHEAGTVCPTVTHTIASPVS-------------RNQELKAGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQSPAPITHQPLGSFGVVSTYSSE-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q49AJ0-1", "uniprot_id": "F135B_HUMAN", "id": "Q49AJ0-1", "name": "Protein FAM135B", "aln": "-MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESSSLHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQLKVDLHFTDSEQQLRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVALQQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSSEGSFYITSENCMQHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTE--------------------------LEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPATGHNLSVYPNFDVPVTSPTIMNLKDKEDNCMVNSN----------------LSFREDLVLSTIKPSQMDSDEEVIRC-------PEPGENVATQNHMD------------MCSESQVYISIG--EFQNKAG---------VPEDECWTGQTSDAGTYPVADVDTS-RRSPGPEDGQAPVLTYID---------VKSSNKN--PSRAEPLVAFNAQHESRSSRDKYGLDRTGLSK-------------------VVVGGSHQNAISSDKTTLHELSTLGKGIDQEGKMVLLSLKLTPSEP-CDPLSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKR-------SSSIISDSGIESEPSSVAWSEARSRALELP-------SDREVLHPFVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEDER-------------EVALTKLTKSVSAPHISSPEEAAEDADTK-QQDGGFAEPSDMH-----------SKSQGSPGSCSQLCGDS-GTDAG-----------ADHPLVEIVLDADNQQGPGYIDIPK---------------GKGKQFDAQGHCLPDGRTENTPGVETKGLNLKIPRVIALENPRTRSLHRALEETPK-GMPKDLN-VGQQALSNSGISEVEGLSQHQVPELSCTSAADAINRNSTGQQSQSGSPCIMDDTAFNRGVNAFPEAKHKAGTVCPTVTHSVHSQVL-------------KNQELKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTLFPITHQPLGSFGVVSTHSST-LDEEVSERMFSFYQAKEKFKKELKIEGFLYSDLTVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSQ6-1", "uniprot_id": "A0A8M1PSQ6_DANRE", "id": "A0A8M1PSQ6-1", "name": "", "aln": "MMSEVQGTVEFSLELHKFHNVDLFQRGFYQVRAGLRVSPRVPHRITATTPGYTGECSFSNAGVHDGGVFSRIFQILYRNEEVTLEDHINFRLHLLLDGERVEEAVSEVDVQLKLDLHFTDNEQQLADISSVPVISSRTLGLHFHPQQGLHHHLPVMFDYFHLSVISVSIHASLVALHQPLISFARSGKGTWLGKGSPESEAPPSAMSVENLMFGAGYCKPVPTEGSFYVPSENCLQRAYTWHRRICKLLLAAHRALRSYYTTLMKEIPQLQHIQ--------------------------TEDLPLEETLNQLTIELQLQSGHEKVAEQISKDLTQLCAQLSALWTQFLESTVPNPYIRSYLAQEHHTLRVRRFSEAYFFTEHPKESSLTFQEELINRHAQVSTEMRNSDYLLRMPPLPVECLDIDGDWSSLPIIFEDRYVDTPCLDYNVVHEQNQAVLNSQPCFEPTRVKGQTASPAEK----------------TQDTSLPATSPEEPPSEDCTEMPTYMTLTDHQDDDVTEHIKPRPQAE------------TLTDHVEEADIDGCEFITTSSNS------RIHSVDEVTCQYENDGNTMSVDTDDV-IDNQEKTSCQKEAANESD---------HTSSQQTNVFNSGQPLLLVPTDLGELPDLTSLGSFEFLPTYNH-------------DDNLETPGDTGSPDNQEPQTVFDNRHIQAPAKDYGGKDTSPGILLKATLPGTDPLVTSPSRNVIHQIRRLS-ETPPRGVFLGGAKLMNR-------SSSVISDSGIESEPSSVAWTLEGRGVVAG---------GRDILQSLARCRTAHQSSLEGLQTESHGSLPSATQASLTSISSLPYEEEE--------------DRQLNTLTKSASAPQISSPDDTEEDRETPNQETRTVCEANQVTGTRCEANPMRQNKESANEVKRNLQMEETTQQDTTNVLVANHIRDEAANEVKQTLQEVTREDGNTTTNQEKRNVCVANQLRKSEVAANEVKQNLQGVFREDGNETSNQEIDIEESSNQDITDLTFVNPEMLLYQQFLMDSGKDATLEELTENSKDFQGNILLKEYLMDESTEICRCEDEYCEHKRKLESNQYHKDADDISVCH-IHLNELEVASMENLPEP-TTNDKRTHGIAANEKERPADPIEPPTNERDQQILEGQSRINKVPSTGLAFVNK--KVVEVVNLSVSCAPTCLPFSSVLRDSPSVSGISTRQATSPITHQPLGSFGIISSNSFFGADQEINERMINFFKAKEALLRELVFRGTLYSDLPYLASEHPYFPPEEDDTEFEDGIHLVVCVHGLDGNSADLRLVKTFVELGLPGSRLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLTIHRISFIGHSLGNVIIRSVLTRPRFRCYLCKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDPRQTFLYTLSKKPGLQFFKNVVLVASPQDRYVPFHSARIEMCRTALKDRTTGPVYTEMINNLLQPLLSAPNCRLIRQNVFHALPNTANTLIGRAAHIAVLDSELFLEKFLLVAGLNYFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12103-1", "uniprot_id": "YD109_YEAST", "id": "Q12103-1", "name": "Putative lipase YDL109C", "aln": "---MEAGRSADEVLYHNQSSVKLGELERYVITYELYQGDSIPADITLDSLWVKIKN----------------------------TTKLSYKPAYLLGPFILYCDVRAKDYESSYKIICSADKPVFQSNLQAQQKFIAELSLHHIKPR---------------YVWIVDIVSQILFNKETKVTFEIVVGNSKASLKRKIRCNDSLPDKACNILHTGLSVHRLTTADIWKVPRP--IDMSQKSHLVILTHGFQSNVSADMEYLMEEIYKAQMNNPN---------------------------ERLVIKGYMKNACETEKGIKFLG---------VGLANYIIDELYDDSVGKISFIGHSLGGLTQTFAICYIK-TKYPYFFKKVEPINFISLASPLLGIATSTPNYVKMSLSMGIIGTTGQELGLKDGNYGDKPLLYLLS----------------------------------------------------------------------------------------------------------------------------------------------------------------EESLISVLARFKRRTLY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANAVNDGIVPLYSSSLLFLDYS-------------------------------QLLQKLGGQTTAPCDPLFQPEVSPIGELP----------------------------------------------------------------------------------------------------------------------------------------------------------------------NHSDVANDDDGINASSWNTFWKSKENNCDKKSK----------------------------------------------------------------------------------------------------------------------------------------------RLMNASVIKSMKSVLLSPCP--------------------------------------------------------------------------DAKFFS-------------------DPDARVATIIHDKIYTEKNLPPPSPTLYEGTAAK------------------------------------------------------------------EGETRKTRKEMEEIIARRWHKGMHWRKVVVLLKPDAHNNIIVR----RRFSNAYGWPVVDHLVTAHFQRDDPIASPMQDKQFAEEDINMATGG----VEPNKFYSWLTKIEDPSVYHGGIVSTASQLASSWISKHSSVTD--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :: .*.* : * : : :* : . : :: **. : : . . : : .. . * **. . * * : : :: ::. ::* : . . .::. : .. . : :. : * : : : . : .. : * : : :.: : . : : *: : : *:* . :: . .:* : :: . . :: : : . * **: . *::: . :. ..*. : .**. * :: . ..::.*..** . : . : : . :. .. : .: :.. . :*. . *.. * : * : * .** : . : .* * : . :: : :* **: ::: * :*: * ..::* . :* :. ::.. :: * ::: : . . : : .:. : .: *.: *.: : :: ", "identical_positions": 49, "similar_positions": 189, "identity": "3.08%" }, { "cls_id": "homologset.agr.SGD:S000002269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0M0-1", "uniprot_id": "EXOS7_MOUSE", "id": "Q9D0M0-1", "name": "Exosome complex exonuclease RRP42", "aln": "MASVALSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLG-HTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSANATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLRSLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGAKDIELSDDPYDCIRLSVENVPCIVTLCKIGCRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMESSKRVGKVLHVSLQSLLHKEESLGPKRPRVGFLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZNY7-1", "uniprot_id": "A0A8I5ZNY7_RAT", "id": "A0A8I5ZNY7-1", "name": "Exosome component 7", "aln": "MASVSLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLG-HTDILVGVKAEMGTPKLERPSEGYLEFFVDCSANATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLRSLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGCRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMESSKRVGKVLHMSLQSLLHKEESLGPKRPKVGFLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15024-1", "uniprot_id": "EXOS7_HUMAN", "id": "Q15024-1", "name": "Exosome complex component RRP42", "aln": "MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLG-HTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12277-1", "uniprot_id": "RRP42_YEAST", "id": "Q12277-1", "name": "Exosome complex component RRP42", "aln": "-MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSECIVSIKSKVVDHHVEN---ELLQVDVDIAG-------QRDDALVVETITSLLNKVLKSGSGVDSSKLQLT-KKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFDDLEVEELPTFHD-YDMVKLDIN-PPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKITSPIRSVALNDSNVKSFKPHLLKQG--LAMVEKYAPDVVRSLENL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::::* . :* . .:* *** .::* :*: **.:..:.**:*: . :: :*.:*::: ::*. *:. ** :. *.. : *:. * ::::. *.** .* :: :::.: ::****::.. .: .. **:*: :** .* :*:: *: ::: .* ** ::*.:: * :. *. :* . ::*.: :*. : .*::* :. :.: :*.*. .. : :*: : . ::. .:::. *.* ", "identical_positions": 55, "similar_positions": 123, "identity": "18.84%" }, { "cls_id": "homologset.agr.SGD:S000002270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYA7-1", "uniprot_id": "A0A0G2JYA7_RAT", "id": "A0A0G2JYA7-1", "name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "aln": "MCGWEPLAAHAHSRLGGRRTRTGSTPREMERVLVDALLTQSREPCALLGALCGGEASAERAETLRLVLQRLEE---RGAG-VGALAKAAHEVARGHLVPLLYVSQG---GGP-------ASPRVLRAASAALRSCARLAG-PELAVTLAEEALRGLPG---AP----AVELLAAVAPCLRASEDAPLLRCLARASVELALAG-----------DAPPAVGARLLPALAQSAEPALRAAWDALSSVEPG----AEGSTGPELLVLCALAEKLLPKP-------EHHGDFDARLCGRFWRTVQAGMSRAQDALTRKRARYLLQRAVQVSAELAVDCTCDPQDTKGPSLFWWSKKKKDELLKFWENYILIMEVLEGNQIHVIKPVLPKLNS-LFEYAVSEENGCWFFHPSWHTCVYRRMFEGENKILAKEGVTHFLELYEVKSLPYSPELSEVMFITGPLMDALSESCLYSRSPGQPLGSGSPLGLKLQKFLVAYVSLLPEETKSHFLLKFIQRMADRHWCAVPVLFLSKALASLPSCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQAAMRLVDVEKVSLSDVSAFLMSLRQEE-SLGRGTQLWTELCDWLCVNERYFKQSS-IGGSDG--------HEASLNAYVKNLVQEFVKSPGWEK-ESSFVPDWLEARLTALMVLLAVDVKGIKTKFREKQRTQNVLRIFLDPWLDALGKLGTNAYMPLLRTDRCLQLLVRLLHSCVPRGSSAQDD---EVSAALWASVMSAAESVSQFVLRRLTMNELQDVADLDRCQLYLTVLAELVSLQVKLGWKAGNPVSRVISPLRNACVHHLQEAEGRQEPTLSHQVQTAVSMATLAALCEAEDRHPVLQPDSSSAEAVDRFLSALPLNRMLQKPHSEGQSIGVCPLENGSVFEESSSSQGWGKVVAQYLHDQWVCLSFLLRKHQGLIPATESDVLKCCLPAVEMPVPTLQSALDVLTVLPAGLVLPVFHCMEVLVP-KLLTSEETLCIESFDVAWKMISSLSNTQLTFWPNLKAFVHFVFNNEILTIAAKLKGPAYDKIKEIMCKMIEMSSIKSGVFNILICYCCQSWLAAASGVAQGSFSSAKDYSELVLEACVFGTVPWSCECLFLFLILILG-CGQVCVLSFYILSTKREDYYVRICVIKFLCLLDGSDVSHKLFLEDLAVKLLDKDESASRSRTRYHENSLQHRVKNRVWQTLLVLFPAFDQNFLHG-IIDKVFHAGFT-NNQASIKYFIEWLIILILHK-FPEFLPKFWACFSYGEEKIKTSICTFLSVLSHLDIIVQNIPEK--KLVLKQALTVALQWCLSHNFSVRLYALVALKKAWHL--CKALQFEECGAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYSLETIFYTFPRLSGVTEEEWIALEKFANFTDIPSNVGSQWYLSGITLGELSPGDWSQQDQGSTLGEADSQSEWADVQKKIIPWGHSALDSDLELEFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPSQLVDYLQQKKAEGYTVIGVEQTAQSSDLAQ-YRFPEKSLLLLGNEREGIPVNLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAGPPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q368-1", "uniprot_id": "TARB1_MOUSE", "id": "E9Q368-1", "name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "aln": "----------------------------MERVLADALLTQSREPGELLGALCGGEASAERAETLRLVLQRLEE---RGAG-AGALAKAAHEVARDHLVPLLHASQG---GGP-------ARPRVLRAASAALRSCARLAG-PELAVTLAEEALRELPS---AP----AVELLAAVAPCLRAPEDAPLLRRLGRASVELALAG-----------DAPPAVGARLLPALAQSAEPALRAAWDALSSAGPG----AEGSTGPELLVLSALAEKLLTNH-------ERHGDLDARLCGRFWRTVQAGLGRAQDGLTRKRARYLLQRAVQVSAELAVDCSCSPQDTKGPSLFWWSEKRKDELLKFWENYILIMEILEGNQIHVIKPALPKLNR-LFECAVSEENGCWLFHPSWHTCIYKRMFESENKILAKEGVIHFLELYDVKSLPYSPELSE--FITGPLMDALSESCLYSRSPGQPLGSDSPLGLKLQKFLVTYTSLLPEETKSCFLLKLIQRMADRHWCAVPVLFLSRALASIPSCKALGGEGLLALRDVLQRTMITHQVLLRGAAQCYLLQTAMRLVDVEKVSLSDISAFLLSLRQEE-SLGRGTVLWTELCDWLRVNERYFKQSS-LGGSDG--------QEASLNAYVKNLVQEFVKSPGWEK-ESSFMPDWLDARLTALMVLLAVDVEGLKTKFREKQRTQNVLRIFLDPLLDALGKLGTNAYMPLLRTDRCLQLLVRLLHSCVPRRPGAQDD---EVSTALQGSIMSASESVSQFVLRRLTMNELQDVADLDRCQLYLTVLSELMSLQVKLGWKAGNPISRVLSPLKNACVRHLQEAEDRQEPTLSHQVQRVVSMAALAALCEAVDQYPVLQPDSPNAEPVDRFLSALPLNHVLQKPRSEEQSIGVCPLENGSVFEESLSSKGWGKVVAQYLHDQWVCLSFLLRKHHHLIPSTESDVLEGFLPTAETPVQALQAALDVLTVLPAGRILPVFRCMEVLVP-KLLTSEETLCIESFDVAWKIISSLSNTQLTFWPNLKAFVHFVFDHEILTIAAKLKGQVYFKIKEIMCKMIEMSSIKSGVFNILIRHCCQSWLVAASGVSQGSFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQGCAANVIIENAKREDYYVRICAIKFLCLLDGSDVSHKLFLEALAIKLLDKDESASRSRTRYHENSLQHRVKNRVWQTLLVLFPAFDQNFLHG-IIDKVFHAGFT-NNQASIKYFIEWLIILILHK-FPEFLPKFWACFSYGEEKIKASICTFLSVLSHLDIIVQNIPEK--KLVLKQALTVALQWCLSHNFSVRLYALVALKKAWHL--CKTLQFEECGAWTAVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGVTGEEWIALDKFANFTDIPSNAGSQWYLSGTALGELSPGDWSQQDQGSTLGEADSQSEWADVQKKIIPWGQSALESDLELEFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPSQLMNYLQQKKAEGYTVIGVEQTAQSSDLAQ-YRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAEPPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13395-1", "uniprot_id": "TARB1_HUMAN", "id": "Q13395-1", "name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "aln": "----------------------------MEWVLAEALLSQSRDPRALLGALCQGEASAERVETLRFLLQRLEDEEARGSGGAGALPEAAREVAAGYLVPLLRSLRGRPAGGPDPSLQPRHRRRVLRAAGAALRSCVRLAGRPQLAAALAEEALRDLLAGWRAPGAEAAVEVLAAVGPCLRPREDGPLLERVAGTAVALALGGGGDGDEAGPAEDAAALVAGRLLPVLVQCGGAALRAVWGGLAAPGASL---GSGRVEEKLLVLSALAEKLLPEPGGDRARGAREAGPDARRCWRFWRTVQAGLG-QADALTRKRARYLLQRAVEVSAELGADCTCGPQEGNGPSLFWWSERKKDELLKFWENYILIMETLEGNQIHVIKPVLPKLNN-LFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILSKEGVIHFLELYETKILPFSPEFSE--FIIGPLMDALSESSLYSRSPGQPIGSCSPLGLKLQKFLVTYISLLPEEIKSSFLLKFIRKMTSRHWCAVPILFLSKALANVPRHKALGIDGLLALRDVIHCTMITHQILLRGAAQCYLLQTAMNLLDVEKVSLSDVSTFLMSLRQEE-SLGRGTSLWTELCDWLRVNESYFKPSP-TCSSIGL-------HKTSLNAYVKSIVQEYVKSSAWETGENCFMPDWFEAKLVSLMVLLAVDVEGMKTQYSGKQRTENVLRIFLDPLLDVLMKFSTNAYMPLLKTDRCLQLLLKLLNTCRLKGSSAQDD---EVSTVLQNFFMSTTESISEFILRRLTMNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDSGQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAGPLESFLSSLQLNQTLQKPHAEEQSSYAHPLECSSVLEESSSSQGWGKIVAQYIHDQWVCLSFLLKKYHTLIPTTGSEILEPFLPAVQMPIRTLQSALEALTVLSSDQVLPVFHCLKVLVP-KLLTSSESLCIESFDMAWKIISSLSNTQLIFWANLKAFVQFVFDNKVLTIAAKIKGQAYFKIKEIMYKIIEMSAIKTGVFNTLISYCCQSWIVSASNVSQGSLSSAKNYSELILEACIFGTVFRRDQRLVQDVQTFIENLGHDCAANIVMENTKREDHYVRICAVKFLCLLDGSNMSHKLFIEDLAIKLLDKDELVSKSKKRYYVNSLQHRVKNRVWQTLLVLFPRLDQNFLNG-IIDRIFQAGFT-NNQASIKYFIEWIIILILHK-FPQFLPKFWDCFSYGEENLKTSICTFLAVLSHLDIITQNIPEK--KLILKQALIVVLQWCFNHNFSVRLYALVALKKLWTV--CKVLSVEEFDALTPVIESSLHQVESMHGAGNAKKNWQRIQEHFFFATFHPLKDYCLETIFYILPRLSGLIEDEWITIDKFTRFTDVPLAAGFQWYLSQTQLSKLKPGDWSQQDIGTNLVEADNQAEWTDVQKKIIPWNSRVSDLDLELLFQDRAARLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQ-YCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLSHGDTKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QV42-1", "uniprot_id": "A0A8M1QV42_DANRE", "id": "A0A8M1QV42-1", "name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "aln": "----------------------------MSNLLINTLLSHYPDSESLLDTLCWTNTTNPDTEKIEALTVLIKELSIKPQE--ERFIRKIQSVLWNQCMPVIQTILRSEDGGK----------NLLNAVCGLFAVCVNVCQSSDVPEQILQALLPVLMTKDDANHEANRADIEVAIEAIGVLLSSISNDRSIISRTLSSTLNCVKHLSDSIISKIIVRIWFTMLKSCGEDAESEVLLQIWDDLLRWHQRDQ--TDTASTRVLLCLTALSDHLCSSE-------TSPNRPDPRRSQRFFRAVQDGLT-HRDSVTRKRALYLLTRCVSLAEMKKEEVVSIEEHETDEILFRWTPDKQKLLREFWEDYALVLETLEENQIHVIRPVLNRIDM-LVETTTTDIQG-GLFSPSWLLCVYQRMFHSENKAVMKEGVHHLLQLKALHQPAFALAFSQ--FVIGPLMDVLAESSLYHRAPQQNIRDCPELGVKLQIFMVNFFNSLPEENRGSVLLRLIQRLGSRQWCAVPLLFLSQALSCLAPCPLLGSDGLQAFREVLRCTMITHQVLLRGASQCFLLHAAFCLTDVSAVSLDEIFAFLVHFRADE-SLCRGTALWKELCKWLQVNEGCFGLASGASGSDDLPSEYPNGDGAAVFTYTQQKLKTFLTVSANSD-QTGGLPDPAEAELLARAVLLTADLQQMKSE-------EPALDLLLQPLLDVLHRLSTNVYLLLHKTDRSLQLLLRLLHLHVKRSETQLEDTEDVVAVVLKTHVLSVVESVQEFLLRRLTG-ELKELCDLQRSELYLSVLRELIFTFSTVSWYSSNLQQNYLPKLTKHCLRILNE------PSEQNQVQRAVSMATLALLCDVADR-SVLNTQSVAMGSLRSLRQYFYPSSSSSSLHLN-QSLQKPTAVAISHPEDSVVLKDWGRVVAQFIRDQWTCLSFLQRSDGTLQVPEAAEVLR--------------EAVEALALLPGHLVLPVLDFMSSVLPQQMVQCEESLCVEAICASWKVVQALSTNPHDFWSTLQAFVRLAFHQQLLQLTEEQKPRITACIQQVLKELMELAQVRSGVFNVVIQHCCETWLPSDGVQSDTVFSSALLHLNILTEACVYGPVFRRDQRLVQEVQSYVEQLGERCAANTAVSSDVRDDQFPRVCVLAFLCRLDPSHHLHQRLMEELVLRMLNKDAEISKSKVRYYSNSIQHRVKSRAWQTLLLLLHQLRDEFVSECVLSRVCEAGFS-SNQASVKYLIEWTLILVLQR-SPSHIQSLWNCFSLDHEKTKTSICTFLSVLVHLNVLLPKLADK--AVQWRRAVEVSLQWCFSHNFSVRLYALLALKRVWELQDAHVFIEEDLGGLSTVVKACLEQAEAMQNTGNAMKNWSRIQEHFFFSVFHPIRDYSIETIFQIFPRLSEMAEDEWLPLWKFESFVDFPTNSALPLNNPGTDLSELQPGDWIQQDKG----DLELEERWAEVQKKISPWKLSVQEQEPELMAQQRALRLGKLTSSLLVVASLIDKPTNLGGLCRTCEIFGAKALVLDSLRHVNDKQFQALSVSSELWLPMMEVKPAELSDFLQLKKSEGYWVIGVEQTSNSQSLQD-YTFPEKSLLLLGNEREGIPANVLQLLDVCVEIPQFGVTRSLNVHVSAALLVWEYTRQHSGCNTA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD22-1", "uniprot_id": "Q9VD22_DROME", "id": "Q9VD22-1", "name": "tRNA/rRNA methyltransferase SpoU type domain-containing protein", "aln": "----------------------------------MSLPTTRATTATTTHAVVQAVETYIQNQNLLGEIAELDDMLYDLVS-----MHKDNELALKRVLQCIHNLLQTNSKYN----------VRFGPKVFHKLVSVVIADSREDSASRRQLVAN------------------------------------------------------------LLVCVQLHIRKFPRIEAKFVLQQLWSLSQ---------SNERQPHAAQILVHLFDDFVNNLG--------------TECAQELLVLTRNLLQSDVRDDRRSAYFLMHKLQEIDEVLAALQCSEVQ---------------------WSAYVGIMENLEEQQSHLVLPTLSTLLP-RMGLMS---NNLSEDWLDWLRILCIRLLGDNNILVLRWTLKYFLSHFSLEQISRFNLLTQ-------FLAATNRTQLYNPEVPDCLT---------KQQITDFSAQFPAEI-------LLEALVCVPWHAVPLIHWLQAW------------------ELKQLPVVSKELLFKLGARVRSLQNPVLRGEAINYVIFSLSATIDSLSLGD-YLLFMESLYNTIDRYQSHSQLAQKIRN--------------------CSNLEKHIASFN-----------------------------------------------IRCCELVSQMDYKHDVFVAFLEKLRTVPKSKHGWWRLLPIFLHR--------------------------------------------ELDHPEQYLDFYRSVYDLDTSFLESGVSLEQMQQHLLN--------------------------------------------------------------------------------RLDCQTREEKSFVLEHSVDLFVQINLPTWSKLEVLN-----------------------------------------------------LNPLELLDRGTEETFATLSNILSTHDEQLADQNVLPAFISRLGKLKVRETQAILKYAVQNLSSEEYEKCVVDVLEKNTFLLGTMD------CEEYIKAP--------------TSFVIKRMLQGETTTGDARIERAFEQISDTGAMDRVQFIQYAKN-----------------------STGLDISFICDDLLRMNNELSRKKPRYFANCKEHRMKMRIGKALLDLSDRWKWS-------DNLWEAVLCPSDQPNISFMYEYLVSKMLPS-IDLLLEQLKLLATLKPSQQIS-----LVSVVHIYCLTRWESIQ--HEQLVEVFAVLLPLTMGANFQTRLLAQLVLHRICSECEDRSIQMPIADALKKSIKVTLSEKLTEFQCEAR-------------LLLPELGKQCPTSVSDCILMMTNAPFDENISFISCSYDFRMKLKRALETFKRKQSVLIPELATSLAALNG-------------NVQRKMNPVGDIYPESDFVVSNKARDD------HELIVVASLIDKLPNLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAEKTLNILEVNPESLAGFLLEKQMEGYKIVGAEQTAHSTNFVD-FKFPKKSILLLGHEKHGIPANLIGFLDYAVEIPQYGLVRSLNVHVAGSLFIWEYCKQHLN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07527-1", "uniprot_id": "TRM3_YEAST", "id": "Q07527-1", "name": "tRNA (guanosine(18)-2'-O)-methyltransferase", "aln": "-------------------------------MVGGALICKYLPREEQLKLISDLIQNDSLEEVLELIETSPLDITTDSNIETPIFEKITEQVIAYASIDGEAREMFRSSRAEMN--------KALRTSAQLLCCLPSVWHKFQVWMSYRLNDIISENYKHLFNDNFGKKIVQPFFDSFAEEQNANIKHENLHLDILSLLHYLEVVYLFDECKNGISSKCLDFIIVPLLGCNSEEIADSCSKLMRWHIKYLSKCCNTDSNFDKLIWTFIKQLYAEGS-------QQAWKQKNSLSFLLRFLLAAELSPELITYIKTDAYWRHIQTELDNDVHEHRKLALSILKLTIQKLSSHGITLQTTFYKCNDLANIEMLGSWKKFTTLYEMIALDTSLNQIQAAKQDIIKIFDNEHLHHSWGLILLSTGLKSSMESVRKYMMTLMFSITNMSAFSSN-----LPLLTKTLLPAAMSAHYFDVKGVSCPHGEKLSLFVNNLLSQTTEGISDILFEILKLLVEKGTSFDPSRIYLSYGILVFFQNNKQKTINSDHLSLIRKLYDFAAEEEVLETTIQTIYLKFLLYIDPSVSASELLFTLVSHIKLKGGTYKYVEPLFEDYRDLAVSHFDDLQAKENLTTNIG---------KDTIFDLLASIIFDFKDIDITPD--------------------------------------FLIEVAKSKQDIPVYTSKAVTFLTQLLSGEPSNGYTYENATALLSYPNFTIST--------------------WKSINVNNLFKSVMEKFSLDKFKFFAEIYQKTYECRFDTIELNFNDLLSLYEMVKKSANQCSRE------------------------------------------------------------------SFKVKDSAYSSYFELLNTFLKTYALNRDSSEGNDDELHILLRLVDENINKDNGNYLG----------------NLAVCKLLYFIIDSYIHCSTSVSDDDIFIVK--FIFEKFSFIWECINSERLVLKERDLHLMLIKGLFHPVILYFGSNQYIDTLTSKLEEHAQTIISLSYSRRSLLPLLG-----SQLRVFMKFYGKLLREDVNYWWLINIIVGVFKQPQMDVNLYKLKPVISSLFDHKLNNYYIKGDELYEKVYGPDEILARVSIIDSILYANDQLKIRLIEKVTEKTNALYAIKRTDGAEALQRLLQWQLLLLSLLTTNEKKLSETSMIRILKSIEDESSPLVRVYKEWFISSKVVDYYKTGNPKFAEDYLFSLLEDHSKPVFVVSAEKICFMVLKDLRNDEKKYGFTQLLDRFICTLVPNAASNKPLVRHFSNSLIISLWPTFKAYLSDHTLRNIIENLYSNAKKTQIFGQYRAGDAN------------IWDLKGDRKLTNMFGGVLKKVTDHDCPYISESVFEKYLQEKDIVPIGTDERSLWLDKRDTNTESVNNAN--------------ISCDTSPLQTKSGAWETVLDLDNKKSNDVVTRSELIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQDIKVKNHPQFKNVAVTADRWMPMEEVALDEIASFMKEKKKEGYTLIGLEQTDKSVKLDNNFQFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIVHSYTVQHM--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . : : : . ..: : : . : : : : . : : ..: . : : : .: . :* * : . : : : . :: . . : : :: :: . : . : . : : . :. . : : .: : . : . : : : : : *: . : : : . * . . .*:: . : . . . : : * : : * .* : .:. . : . . : : : :: ::. . : : :: : . : : : :. :: :: : * . . . : .:: . : . .: . : : . . . : . : .* : : . . . .: . :. : . . :. . * : : . : *:**:**:** .****:.* *:::*. * : .. :* :::::: : : ** .: .:: *: *** ::* *** :* .: : : **:**::*** * *** .:: ** .:** * *: **:*::.: :::: .* *: ", "identical_positions": 61, "similar_positions": 222, "identity": "3.64%" }, { "cls_id": "homologset.agr.SGD:S000002272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05A13-1", "uniprot_id": "S16C6_MOUSE", "id": "Q05A13-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "------------------------------------------------------MNSVADTAIFFGKFLYYFLESLVFKVIPKRK---KDVSGEIVLITGAGSGLGRLLAIHFASHGA-TLVLWDINQEGNMETCRLVKQ------------------------KGDVKVFAYKCDCSSRIEVYRVADQVKEEVG-------------------DVTILINNAGVVTGKSFLNTPDHLVEKSFLVNAISHFWTCKAFLPAMVKANHGHLVCISSIAGLVGINGLSDYSSSKFAAFGFAESLFLELTMIMK----TKVKSTIVCPYFIK-TGMFEGCTT--KYPLLLPLLEQEYVAQKIFNAILEEQVYLIIPKFAYVALFLKQIISPKMMIALGEYLGVDTC-----------MTSFTGRVKAEELQMETKRKEQ-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN35-1", "uniprot_id": "D3ZN35_RAT", "id": "D3ZN35-1", "name": "", "aln": "------------------------------------------------------MHAVADTVIFFGKFLYYFLESLVFKVIPKRR---KDVSGEIVLITGAGSGLGRLLAMHFANHGA-TLVLWDINQEGNMETYKLVKQ------------------------KGDVKVFAYKCDCSNRTEVYRVADQVREEVG-------------------DVTILINNAGIVTGKSFLDTPDHLVEKSFLVNAISHFWICKTFLPAMINANHGHLVCISSIAGVVGINGLSDYSSSKFAAFGLAESLFLELTMVRK----TNIKSTIVCPYFIK-TGMFEGCKT--KYPLLLPLLEQEFVAQKIFHAILEDQVYLLIPKFAYFTLFLKQLISPKMMIALGEYLGVDTC-----------MTSFTGRAEAELLQTETERKEQ-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQA3-1", "uniprot_id": "RDHE2_MOUSE", "id": "Q7TQA3-1", "name": "Epidermal retinol dehydrogenase 2", "aln": "--------------------------------------------------MSQNLESVKNLLVFLGKSLLSVLEALLFHVISKPR---KNVAGEIVLITGAGSGLGRLLALQFARLGA-VLVLWDVNKEANDETHQLARE------------------------AGAARVHAYTCDCSRREEVYRVADQVKKEVG-------------------DVSILINNAGIVTGRNFLDCPDDLMEKSFDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFIETLAKKQ----WGIKTTIVCPFFIK-TGMFEGCTT--KCPTLLPILDPEYAVRKIIDAILQEQLYLYMPKFLYFIVFLKSILPIKTGILIADYLGVFHM-----------TEGFTG-----------QKKKT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZS85-1", "uniprot_id": "D3ZS85_RAT", "id": "D3ZS85-1", "name": "", "aln": "--------------------------------------------------MPCNLESAKDLLVFLGKSLLSILEALLSHVISKPR---KNVAGEVVLITGAGSGLGRLLALQFARLGS-VLVLWDVNKETNEETRQIAQE------------------------AGAIRVHAYTCDCSQREEVYRVADQVKKEVG-------------------DVSILINNAGIVTGRKFLDCPDDLMEKSLDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFVETLAQKQ----RGIKTTIVCPFFIK-TGMFEGCTT--KCPNLLPILDPEYAVRKIVDAILQEQLYLYMPKFLYFIMFLKSFLPIKTGILIADYLGLFHV-----------MDGFTG-----------QKKKS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3Y7-1", "uniprot_id": "RDHE2_HUMAN", "id": "Q8N3Y7-1", "name": "Epidermal retinol dehydrogenase 2", "aln": "--------------------------------------------------MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPR---KNVAGEIVLITGAGSGLGRLLALQFARLGS-VLVLWDINKEGNEETCKMARE------------------------AGATRVHAYTCDCSQKEGVYRVADQVKKEVG-------------------DVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQ----KGIKTTIVCPFFIK-TGMFEGCTT--GCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHA-----------MDGFVD-----------QKKKL-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IZV5-1", "uniprot_id": "RDH10_HUMAN", "id": "Q8IZV5-1", "name": "Retinol dehydrogenase 10", "aln": "------------------------------------------------------MNIVVEFFVVTFKVLWAFVLAAARWLVRPKE---KSVAGQVCLITGAGSGLGRLFALEFARRRA-LLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVG-------------------EVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEK----DGIKTTLVCPYLVD-TGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKC-----------MYPFIAQRKQATNNNEAKNGI--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80ZF7-1", "uniprot_id": "RDH10_RAT", "id": "Q80ZF7-1", "name": "Retinol dehydrogenase 10", "aln": "------------------------------------------------------MNIVVEFFLVTFKVLWAFVLAAARWLVRPKE---KSVAGQVCLITGAGSGLGRLFALEFARRRA-LLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVG-------------------EVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEK----DGIKTTLVCPYLVD-TGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKC-----------MYPFIAQRKQATNNNEAKNGI--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCH7-1", "uniprot_id": "RDH10_MOUSE", "id": "Q8VCH7-1", "name": "Retinol dehydrogenase 10", "aln": "------------------------------------------------------MNIVVEFFVVTFKVLWAFVLAAARWLVRPKE---KSVAGQVCLITGAGSGLGRLFALEFARRRA-LLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVG-------------------EVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEK----DGIKTTLVCPYLVD-TGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILPFEAVVCMYRFLGADKC-----------MYPFIAQRKQATNNNEAKNGI--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L1W4-1", "uniprot_id": "RD10A_DANRE", "id": "A1L1W4-1", "name": "Retinol dehydrogenase 10-A", "aln": "------------------------------------------------------MNIFVEFFLVMLKVCWAIVMAGFKWLIRPKE---KSVAGQVCVITGAGGGLGRLFAKEFARRRA-TLVLWDINSHSNEETAEMVRQIYR--EQDNPMSKEGAVGGVEEVPPFQPQVYTYVLDVGKRESVYSTAEKVRREVG-------------------EVDLLINNAGVVSGHHLLECPDELIERTMVVNCHAHFWTTKAFLPKMLEMNHGHIVTVASSLGLFSTAGVEDYCASKFGAIGFHESLSHEIQASEK----DGIKMTLVCPYLVD-TGMFRGCRIRKEIEPFLPPLRPEFCVKQAMRAILTDQPMICTPRIVYMVNFMKSILPFEAIVCMYRFLGADKC-----------MYPFLAQRKEAMNNNEAKNGI--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2D1-1", "uniprot_id": "RD10B_DANRE", "id": "Q7T2D1-1", "name": "Retinol dehydrogenase 10-B", "aln": "------------------------------------------------------MNIATELFVVTFKIIWSFVLAGAKWFIRPRE---KSVEGQVCVITGAGSGLGRLFALEFARRRA-TLVLWDINRQSNEETAEMAREIYRQLKPSTGSS-----DSVQELPLLQPKVYTYMCDVSKRESVYLTAEKVRSEVG-------------------DIDLLINNAGVVSGRHLLDCPDELIERTMMVNCHAHFWTTKAFLPKMLELNHGHIVTVASSLGLFTTAGVEDYCASKFGAIGFHESLSHELKAADK----DGIKMTLVCPFLVD-TGMFEGCKIRKEMAPFFPPLKPEYCVKQAMRAILTDQPMICTPRVMYMVTFMKTVLPFDAIVCMYKFIGADKC-----------MYPFLAQRKESTNNNESKTGI--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UVK4-1", "uniprot_id": "A0A8N7UVK4_DANRE", "id": "A0A8N7UVK4-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "------------------------------------------------------MIFLMDLQVMLLDVLYFILRSCLRLVFRPRT---KPIDGELVLITGSGGALGRLFALEFTKHGA-EVVLWDVNGEANEDTAKLVR-------------------------ARGGQAHAYTVDVTKREEVYRTADLVREEVGR------------------DVTYLVNNAGVVAGERLLDCPDYLLERTLKVNCHALFWTVKAFLPQMKDKNHGHIITIASVLGLFSTACVEDYCASKFAAVGFHESLAHELLTEDL----DGVKTTLVCPYIVD-TGMFEGCRIREEVALILPPLEPLYCVQQAMNAILIDQPLVCIPRLTYLPFLARALLPWESNAVTYRFMGSDNC-----------MYPFIETMKKRGGNSPLKAD---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VCR2-1", "uniprot_id": "DHB13_MOUSE", "id": "Q8VCR2-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "------------------------------------------------------MNLILEFLLLVGVIIYSYLESLVKFFIPRRR---KSVTGQTVLITGAGHGIGRLTAYEFAKQKS-RLVLWDINKRGVEETADKCRK-------------------------LGAVVHVFVVDCSNRAEIYNSVDQVKREVG-------------------DVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGK----TGIQTSCLCPVFVN-TGFTKNPSTR-----LWPVLEPEEVARSLINGILTNKKMIFVPSYINISLILEKG-PGFSSKHPHGGSQQP-------------VTPIPGDLTPSSDFLKH------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M875-1", "uniprot_id": "DHB13_RAT", "id": "Q5M875-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "------------------------------------------------------MNLILELLLLVGIIIYSYLESLVKFFIPQRR---KSVAGQTVLITGAGHGIGRLTAYEFAKQKS-RLVLWDISKHGVEETAAKCRK-------------------------LGAVVHVFVVDCSNRAEIYKSVDQVKKEVG-------------------DIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLGK----TGIKTSCLCPVFVN-TGFTKNPSTR-----LWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVLKAINRIQNIQ-------------FEAIVGHRTKRK-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z5P4-1", "uniprot_id": "DHB13_HUMAN", "id": "Q7Z5P4-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "------------------------------------------------------MNIILEILLLLITIIYSYLESLVKFFIPQRR---KSVAGEIVLITGAGHGIGRQTTYEFAKRQS-ILVLWDINKRGVEETAAECRK-------------------------LGVTAHAYVVDCSNREEIYRSLNQVKKEVG-------------------DVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGK----TGIKTSCLCPVFVN-TGFTKNPSTR-----LWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQ-------------FEAVVGHKIKMK-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQ06-1", "uniprot_id": "DHB11_MOUSE", "id": "Q9EQ06-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "------------------------------------------------------MKYLLDLILLLPLLIVFSIESLVKLFIPKKK---KSVAGEIVLITGAGHGIGRLTAYEFAKLNT-KLVLWDINKNGIEETAAKCRK-------------------------LGAQAHPFVVDCSQREEIYSAAKKVKEEVG-------------------DVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGR----TGVRTSCLCPNFIN-TGFIKNPSTN-----LGPTLEPEEVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVK-------------FDAVVGYKDK-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYS8-1", "uniprot_id": "DHB11_RAT", "id": "Q6AYS8-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "------------------------------------------------------MKYLLDLILLLPLLIVFCIESFIKRLIPKKK---KSVAGEIVLITGAGHGIGRLTAYEFAKLNT-KLVLWDINKNGIEETAAKCRK-------------------------LGAQVHPFVVDCSQREEIYSAVRKVKEEVG-------------------DVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGC----TGVRTSCLCPNFIN-TGFIKNPSTN-----LGPTLEPEEVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVK-------------FDAVVGYKDK-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBQ5-1", "uniprot_id": "DHB11_HUMAN", "id": "Q8NBQ5-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "------------------------------------------------------MKFLLDILLLLPLLIVCSLESFVKLFIPKRR---KSVTGEIVLITGAGHGIGRLTAYEFAKLKS-KLVLWDINKHGLEETAAKCKG-------------------------LGAKVHTFVVDCSNREDIYSSAKKVKAEIG-------------------DVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQI----TGVKTTCLCPNFVN-TGFIKNPSTS-----LGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVK-------------FDAVIGYKMKAQ-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR28-1", "uniprot_id": "Q9VR28_DROME", "id": "Q9VR28-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "----------------------MTASP---GLLHMD------------QPLRAIYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISGQVVLITGGGGGVGRLIALNFARLQA-RIVIWDINQEAIKTTVDLLAKHGY------------------------DNCKGYVVDISDREQIYQRASQVTEEVG-------------------PVDILINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGY----DQIQMSLICPYYIN-TGMFSGVRPR-----MMPMLEPQYVADRIENAVRCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPE----------SMMMFQGRGRVAAG----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIG6-1", "uniprot_id": "Q9VIG6_DROME", "id": "Q9VIG6-1", "name": "", "aln": "----MEKNNNELSAEDAQILANGHAHPNANGVVHQKTEPVAPAADGWRQVLWNTWDAFADVAWFIICCIGYILQDLYYIAFGYPE---KELNTDIALITGGGNGLGRLLAERLGKMGT-KVVIWDINKKGIAETVQIVEEAG-------------------------GYCKGYVVDISKKEEVYKAADVIRDEVG-------------------DITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGH----TNIRTTCICPFFIQATGMFDDVNAR-----WVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFKWTFPWGCVGGLLKRLVPDASPHGLPSSIAVPTVPLNSNSKLTAADIAALDAELSSVTLPAKPPSMLIQRTPSLGERVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O88876-1", "uniprot_id": "DHRS3_MOUSE", "id": "O88876-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "----------------------------------------------------MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKL---RDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQ-------------------------MGTECHYFICDVGNREEVYQMAKAVREK-------------------VGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCP------GVSATTVLPFHTS-TEMFQGMRVR--FPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTC-----------MNTFKGRT---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNF2-1", "uniprot_id": "A0ABZ3NNF2_RAT", "id": "A0ABZ3NNF2-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "----------------------------------------------------MVWKWLGALVVLPLQMIYLVTKAAVGLVLPPKL---RDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQ-------------------------MGTECHYFICDVGNREEVYQMAKAVREKVQPTGTGCPHGSTAPSCPQVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCP------GVSATTVLPFHTS-TEMFQGMRVR--FPNLFPPLKPETVARRTVEAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTC-----------MNTFKGRT---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75911-1", "uniprot_id": "DHRS3_HUMAN", "id": "O75911-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "----------------------------------------------------MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKL---RDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQ-------------------------MGTECHYFICDVGNREEVYQTAKAVREK-------------------VGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCP------GVSATTVLPFHTS-TEMFQGMRVR--FPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTC-----------MNTFKGRT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3K9-1", "uniprot_id": "Q9W3K9_DROME", "id": "Q9W3K9-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "--------------------------------MSKVTQSADNGSNANSNDIYNIVLLVVDIVMLIVKFWLAIAEAIVGLFRAPPL---DDVNGKVVLITGTGHGMGKEMALQYAKLGA-TILCWDVNEQTNNQTVKEIK-------------------------NNGGKAFGYVCNVTKREELIELAQKVRKEHG-------------------FIHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQ---NNVKLTTIYPYMID-TGLCKNPRYR--FPNLFKLIPADVAAGSIIEAQRQGLEEAAIPRHFVAAEKIGRLIPRKAMRLVNDFFDTG-------------VDTDKS-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKB8-1", "uniprot_id": "Q9VKB8_DROME", "id": "Q9VKB8-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "-----------------------------------MIEREIIHTTPASKRIFDVLKDVLQFFELYVRILLELFVSLVQIVLPKKQ---KDVSGEIVLITGTGHGIGRELALHYASLGS-TVVCVDIDGKNNLQTVEKAKR------------------------LNLGEVYSYSCDVSKRDEVTALADRIKSDVG-------------------CISVLVNNVGIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELRQGPFR---DLIRTTTIFPYMTN-TGLCKHPKVK--FPSILGLLDPKQVAKRIVEAHRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDFIDSG-------------VESDLI-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCR9-1", "uniprot_id": "Q9VCR9_DROME", "id": "Q9VCR9-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "MVETATTTTITRTTTAVPAGAVTVTGPTASATPTATQAAAQAHRNDETTRAIFNLKVIVFLLLLPLVLLAVFLKHLLDYLFALGLKE-KDVSGKVALVTGGGSGLGREICLELARRGC-KLAVVDVNSKGCYETVELLSKIP------------------------RCVAKAYKNDVSSPRELQLMAAKVEKELG-------------------PVDILVNNASLMPMTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDC----DYVRTTVANAYLMRTSGDLPLLSDAG-IAKSYPGLPTPYVAEKIVKGVLLNERMVYVPKIFALSVWLLRLLPTKWQDYMLLRFYHFDVR-----------SSHLFYWK--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07530-1", "uniprot_id": "YD114_YEAST", "id": "Q07530-1", "name": "Uncharacterized oxidoreductase YDL114W", "aln": "----------------------------------------------------MVRKNKINRASGTTKHLKDFPSVILSLPSYNPS---ILSKNATALITGGSSGLGFELAKELSRRIN-KVIVADIQSFPTFAQVEYNN------------------------------IFYYQCDITSLDEIKNLKKAIERDHG-------------------NINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIK-TNMFIDVPTP--SKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSGMDHVTS---------TSPRAINPKRSA-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** . .:* . : . : : : : . : ::**.. : :* . . : * * : : : . * :* . . : : . : : . . . . ", "identical_positions": 10, "similar_positions": 39, "identity": "2.17%" }, { "cls_id": "homologset.agr.SGD:S000002274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52590-1", "uniprot_id": "NU107_RAT", "id": "P52590-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDPEVTRTARKHSAHKRVLIQANQDENFGTTTPRSQIIPRTPSSFRQPFTPPS-RSLLRHPDISYIFGTEGRSPRHIQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGFYTNTEHHSMTEDINLSTVMLREDDPGEAASMSMFSDFLQSFLKHSS-TTVFDLVEEYENICASQVNILSKIVSRATRWDWQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGDFSDNIEFYAKSVYWENTLHSLKQRQLLSYIGSTRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLHHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTLDETEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHVVQKFLILGDIDGLMDEFSKWLSKSRSSLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLINEKHTNLIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPSLDTATTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNERFKHMNSAPQKP----TLLSQATFTEKVAHEHKEKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEED-------PERAHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH74-1", "uniprot_id": "NU107_MOUSE", "id": "Q8BH74-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDAEVTRTARKHSAHKRVLIQANQEDNFGTATPRSQIIPRTPSSFRQPFVTPSSRSLLRHPDISYILGTEGRSPRHTQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGLYTNTEHHSMTEDVNLSTVMLREDDPGEAASMSMFSDFLHSFLKHSS-TTVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKMVVETLFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSHMGSTRPLVTELDPDAPIRQKL-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTQDDSEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDVDGLMDEFSKWLSKSGSSLPGHLLRFMTHLILFLRTLGLQTKEEV-SIEVLKTYIQLLISEKHTSLIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENICKKDNGEFSHHDLAPSLDTGTTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKP----TLLSQATFTEKVAYEHREKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEDD-------PERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57740-1", "uniprot_id": "NU107_HUMAN", "id": "P57740-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTS-RSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSS-STVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALE---EESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIQTS--VATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKP----ALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKED-------HERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V466-1", "uniprot_id": "NU107_DROME", "id": "Q9V466-1", "name": "Nuclear pore complex protein Nup107", "aln": "---------------------------------------------------------MADSPFPRSSRSGLLR------------------------------TTLNSSMPPQNLSHS---LLILEKSNAEQNELSLMEDTGDDLDRGKSRMDVLFPQFFDVLQAQGNGQEAFEVIQSLTQVCRGVVEQLELEIDHGMGG-EQGARQRESMLTWLRQEINTWRLLHALFYDRILLQTDRQADDEMQDGPTLGGSEKEVIQQLYALNATLREYQLVVDWLEACYD--RGEQQNPLHAHDRMMAWENTLFQLEN-LQGAAFGKGHKIVTRLDPDAPVREKR-PLHALDEEDNLRLSRAIFELIRAGRVDDGLKLCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKLPIEGNPRRDIWKRCAWMLADSKNYDEYSRATAGVFSGHLGSLKTLLHSNWHDLLWAHLKVQIDIRVESEIRG----CCLKNYQPMPDDYWNGRMTMEQIFEELNVAKDASVRDFAQSQLGIIQRHLILDTCGELIQHMVRWVEKDTSQQSPHQLRFMAHIVLFLRQIGRVEQERQ-AEKIVAAYVEALIARGEPQLIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRLAHQP---LGEFGEPQSGEISAIDQRKISALEWLIHLPEQRGELLWQANAMIRTYLASSKVECMRQTFRMVPADIVQQLVSLY---GSVDNIPPRE--ECCLKEYLCYKAYLSGVDSFVEWNRLQQNRPKKPQTSHAASSQDNFTERMASERKEQAHRSEVVRWEHKVKEQAKQTIELLYNVLMFPDKGWLVDPFIAKLPENAVQLSWDHRLLQMEKLRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQLYKVYTKHKLAELLAKIADASLELLNSKLDPWGYPITT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52891-1", "uniprot_id": "NUP84_YEAST", "id": "P52891-1", "name": "Nucleoporin NUP84", "aln": "---------------------------------------------------------------------------------------------------------------------------MELSPTYQTERFTKFSDTLKEFKIEQN--------------NEQNPIDPFNIIREFRSAAG------QLALDLANSG--DESNVISSKDWELEARFWHLVELLLVFRN-ADLDLD---EMELHPYNSRGLFEK----KLMQDNKQLYQIWIVMVWLK-----------------ENTYVMERPKNVPTSKWLNSITSGG---LKSCDLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNP--VIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTTQRVFDETEQEYSPSNE-ISISFDVNNIDMHLIYGVEWLIEG-KLYVDAVHSIIALSRRFLLNGRVKALEQFME---RNNIGEICKNYELEKIADNISKDENEDQFLEEITQYEHLIKGIREYEEWQKSVSLLSSES---------------------------NIPTLIEKLQGFSKDTFELIKTFLVDLTSSNFADSADYEILY--------EIRALYTPFLLMELHKKLVEAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVARTATLSN------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. : . : . . *:::.. . . . :. . : * *. .: * :: : : : .: . ** * : : : :*: **: . *.. . : . :. * * *:*:: *. *.*:: : : :: ** ** ::. . .* .: . * * : : :* :.. * . :* : :*: : :::. : *.** . :** : . : : *.. : ::. :: :*. : . :* . . .:::: .. .. : . :* . *:: . .. : **:::*: : : :. *. ::: :*:. * . . *. *: * : : : :*. : : . *. :: * . * : ..:.: : : . . . * * ::**: : : . *: * :* : :. .: : : : :: . . :. : : :.* . :.. : * : . ..:. : ::. : :. * : ..*: . :.* . : : : . :: . .: ::. ::.*. ::* :: . : .: : * : ", "identical_positions": 67, "similar_positions": 243, "identity": "7.03%" }, { "cls_id": "homologset.agr.SGD:S000002275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z953-1", "uniprot_id": "D3Z953_RAT", "id": "D3Z953-1", "name": "", "aln": "-----------------------------------MELKKDSNAVAIDMLLIVHSEKRRAAQATHLDPQADPGALLQNRGGFQGVRNGIRKWQELEENGFQGNLPEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMP--QLLKKFSLAKRLQGDKNGNMRPRQPGGKD--AHAYPWDRSNLKSMP-----LDLRHFEKLDASASQVTLKS----------------GLNELVSDLLQEAHSDLER-VRAIWIWICHHIEYDVEAAQEKDRQAFKPTNILRTRKTNCDGYAGLFERMCRVAG--VQCVTVPGYSKGFGYKTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSG-----------------LVDTATSKFTFLYNEFYFLTHPALFIEDHFP-----DNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETPMIRTVN--------GKATVTIESRAPTLF--------------------MFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSE----------------------------------------------------------------------------IYSSVLEYTLKCNYVDFSVRLPTELHQPVGPSWFSEQMGIRKPSHPDPIIHTS---DGRCSISFVVEEGISILASLHGDDSPITEETKRRYIFQMNREKR----------------------------TELKVQLPHAGKFALKIFVKKRQEQGNFVFVFNYLLCCANTKVNWPMFPEI----YGHWGQDNELLEPLSGVLPANRNIPFKLKLHGIAKALVKGQDTWPLTLN---PEGYWEGSCNTAGCQEVYVMVLENANHNFYSYILKYKVNDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8H8-1", "uniprot_id": "KY_MOUSE", "id": "Q8C8H8-1", "name": "Kyphoscoliosis peptidase", "aln": "-----------------------------------MELKKDSNAVAIDMLLIVHSEKRRAAQATHLDPQANPGALLQNRGGFQGVRNGIRKWQELEENSFQGNLPEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMP--QLLKKFSLAKRLQGDKNGNMRPRQPGGKD--AHAYPWDRSSLKSMP-----LDLRLFEKLDASASQVTVKS----------------GLNELVSDLLQEAHSDLER-VRAIWIWICHHIEYDVEAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRVAG--VQCVTVPGYSKGFGYQTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSG-----------------LVDTTTSKFTFLYNEFYFLTHPALFIEDHFP-----DNKNWQLLKPPQSLRQFENSMYHKSEFYNKGMLSAHPETSMIRTVN--------GKATITIESRAPTLF--------------------MFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSE----------------------------------------------------------------------------IYSSVLEYTLKCNYVDFSVQLPSELHQPVGPSWFSEQMGITKPSHSDPIIHTS---DGRCAISFSVEEGVSVLASLHGDDGPITEETQRRYIFQLNRGKR----------------------------TELKVQLPHAGKFALKIFVKKRQEQGNFIFVFNYLLCCANTKVNWPMFPES----FGNWGQDNELLEPLSGVLPANRNVAFKLKLHGIAKALVKGQDTWPLTLN---PEGYWEGSCNTAGCQEVYVMVLENANHNFYSYILKYKVNDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBH2-4", "uniprot_id": "KY_HUMAN", "id": "Q8NBH2-4", "name": "Kyphoscoliosis peptidase", "aln": "-----------------------------------MELKKDINAVSIDMLLIVHSEKRRAAQGTLSDQQANPSSLLQRGGGFQGVGNGVRRWQKLEGNDFHENLVEKQHPQQPQVITSYNSQGTQLTVEVHPRDAMP--QLLKKFSLAKRLQGDKNGNTRPRQPGGKD--AHAYPWDRSSLKSMS-----LDLQQFEKLDIYASQVTAKS----------------GLDELVSDLLQEAHTDLER-VRAIWIWICHHIEYDIAAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRLAG--VQCMTVPGYSKGFGYQTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSG-----------------LVDTITSKFTFLYNEFYFLTHPALFIEDHFP-----DNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVN--------GKATVTIESCAPTLF--------------------MFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSD----------------------------------------------------------------------------IYSSVLEYTLKCNYVDMGVQLPAELHQPVGPSWFSEQMGIMKPSHPDPIIHTS---DGRCSISFSVEEGINVLASLHGDDGPITEETQRRYIFQLHREKQ----------------------------TELKVQLPHAGKFALKIFVKKRQEPGNYIFVFNYLVCCANTKVNWPMFPES----FGNWGQDNELLEPLSGVLPANRNVPFKLKLHGIAKVLVKGQDTWPLTLN---HEGYWEGSCSTAGCQEVYVMVLENANHNFYSYILKYKVNAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07533-1", "uniprot_id": "CYK3_YEAST", "id": "Q07533-1", "name": "Cytokinesis protein 3", "aln": "MATNLTSLKPPFKVKARYGWSGQTKGDLGFLEGDIMEVTRIAGSWFYGKLLRNKKCSGYFPHNFVILLEERLNSSTENGRQPSKIVESFEKSNKVVIPPVPSRYSDERPRPKKKLSSSMPNSPKKPVDSLTKARKAKSKEMVNEKNIYNTQSSRHHNNSAPNLPLASHSKPQVRNFEESMNNPLPPLPPLPDLDNMRKTDKRAPKKSYSANDLHMARSSREYNYYKDNQKFYDGFIPEKRYSLEEDSISSGLFSNSQYLNDSACSSENSFALMSDFSATSAGSFARHKYAQSFSDSLQRSQNANGCSTKINDSQEFGDSNASSRNGKMGDILRKIIIPKRNTNIYSSSVSSPKSPKAYPKLPDIQNLNLSATPDEARDWIAVKCHLNRARTLTKYDKHPRYMRALEENRDLILHPQDSIYNGLNTNEVKGNTKPGLVDVELAELNIEYIDKMTWKRCIRDGTMTLDSWAQTTFSARYSTVLEKLRGIYIFCTEMFALTDDNGTSDFSAEPQNLEKILYRKHCTPYELTWLFKKLANSLGITCEIVIGFLKTPSAINWEFKYNHCWLRILVNKEWRFIDVILGNVTNPIHEFVNNRKIKKAENSYFLMAPLEMIYTHIPPREFEQHIVPSIDQLSALYLPLVFPSFFKNELKLYKFSTALSFLEDSEIYECSLEIPNDVEVFASVVIPTDNEEASSAYRNMELALTQIKKQKAESGRRIALIKAVLPPNVNKGSLYIHSGVRGTQTSIANIHPLSMMVPLTHKGSNMKYEFVIKIPSESIQKIELYIVEPQSRYLFVGNEYSFEVIQSPSDGIVYSSDEGPNQNRKQPMAIKSPSGRVHELVKSDPHFPYGTWKGSIKIKEPGVWSALVIADSGIGWSVFAEWLCV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.: .: . ** :. . .: : .: :. . : :...: ::: . . ::: : :: :* .. .: . .: ::::: .: : .. ::.* *. * ... .:. ::.* :.:. ** :.* * *.: : .: . ::: ..:: * : .**. : :: : * .:.*:. :. . : . . ** *. : : * * . *: ** ....* .*::.. . : : * : *: *. * * . :: : :: :* *:.* ::* :*: **. . . . : *::... *. :: ..*:*::* * * * ** *...: . :* . :.:: :* .::* : * :: **: : :: : * :*.: * **:*.::: : * * . .::. * : *. ** .:: . ..::.. : .. . : *::: * :..:.: ::: : :.:: . :: **:: . :. : : *: *: . : : .* .*:: :. : . : : : :* .*: :. : * *:** . .:*: ::. .: : * ", "identical_positions": 86, "similar_positions": 267, "identity": "9.68%" }, { "cls_id": "homologset.agr.SGD:S000002277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499U1-1", "uniprot_id": "S2538_RAT", "id": "Q499U1-1", "name": "Mitochondrial glycine transporter", "aln": "MGVSAEPRSLSVARAGLASPVIEKARSALLPSQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQP-SDVGPRRVGMLSVFLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSSKQYFLRGH---------------------PPTALESVILGMGSRSVAGVCMSPITVVKTRYESGAYSYESVYAALRSIYCSEGSRGLFRGLTATLLRDAPFSGLYLMFYSQTRATVLHGADELDAALMP----------LVNFSCGVFAGILASLVTQPADVIKTHMQLSTVKCQCIGQVATLILKTHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMAKMGLKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XD8-1", "uniprot_id": "S2538_MOUSE", "id": "Q91XD8-1", "name": "Mitochondrial glycine transporter", "aln": "MGVSAEPRSLSVAGAGLASPVIEKARSALLQSQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQALQP-SDLGPRRVGMLAVFLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSSKQYFLRGH---------------------PPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESIYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTRTAVLHGTAQLDAALIP----------LINFSCGIFAGVLASLVTQPADVIKTHMQLSPVKFQWIGQAATLIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DW6-1", "uniprot_id": "S2538_HUMAN", "id": "Q96DW6-1", "name": "Mitochondrial glycine transporter", "aln": "--------------------MIQNSRPSLLQPQDVGDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQP-SDHGSRRVGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGH---------------------PPTALESVMLGVGSRSVAGVCMSPITVIKTRYESGKYGYESIYAALRSIYHSEGHRGLFSGLTATLLRDAPFSGIYLMFYNQTKNIVPH--DQVDATLIP----------ITNFSCGIFAGILASLVTQPADVIKTHMQLYPLKFQWIGQAVTLIFKDYGLRGFFQGGIPRALRRTLMAAMAWTVYEEMMAKMGLKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CI8-1", "uniprot_id": "S238A_DANRE", "id": "Q08CI8-1", "name": "Mitochondrial glycine transporter A", "aln": "--------------------------------------MEFSVAHPAVKAFMCGSLSGTCSTLLFQPLDLVKTRLQTLQSGVQPGTGRVGMVTVFVNVLRTEKLLGLWRGVSPSFVRCIPGVGIYFSTYFTLKQRYFSSG---------------------APGPLQAVLLGAGARCVAGVFMLPVTVIKTRFESGRYRYSGVFGALRSVCQTEGPKALFSGLMATLLRDAPFSGIYVMIYSQTKHLLPP--EISQSSYAP----------VANFSCGVLAGVLASVLTQPADVVKTHIQVSPDVFSRTSDVVRYIYKEHGLVGFFRGAVPRSLRRTMMAAMAWTVYEQLMAQIGLKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CAT2-1", "uniprot_id": "S238B_DANRE", "id": "P0CAT2-1", "name": "Mitochondrial glycine transporter B", "aln": "--------------------------------------MEVALAHPALKAFMCGSLSGTCSTLLFQPLDLVKTRLQTLQNNMHPGAPKVGMITVLFNVIRTEKLLGLWKGVSPSFMRCIPGVGIYFSTFYSLKQHYFQEG---------------------SPSAGEAVLLGAGARCVAGVAMLPFTVIKTRFESGRYNYISVAGALKSVCQNEGPKALYSGLTATLLRDAPFSGIYVMFYSQAKKALPQ--EISSSSIAP----------LVNFGCGVVAGILASLATQPADVIKTHMQVSPALYPKTSDAMRHVYVKHGLSGFFRGAVPRSLRRTLMAAMAWTVYEQLMARMGLKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07534-1", "uniprot_id": "S2538_YEAST", "id": "Q07534-1", "name": "Mitochondrial glycine transporter", "aln": "-------------------------------------MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKK-----------ATLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDSNIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAITHIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFTTYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLKLFSGLSMRLARKAFSAGIAWGIYEELVKRFM---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: * :.* *:: :*****:***:* : :: :: . :. * **:* ** :* * .:*:. :. : :: * :* :.* *.**:*.*:** * * .: *: : .** .:: *: ** *****::*:*:::*.::: : * * ..:.:. **: * * *.:**::*: . :. : .: :* * * *::: *.:** :**::: :: ", "identical_positions": 67, "similar_positions": 86, "identity": "18.72%" }, { "cls_id": "homologset.agr.SGD:S000002278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYW7-1", "uniprot_id": "FRDA_RAT", "id": "D3ZYW7-1", "name": "Frataxin, mitochondrial", "aln": "MWTFGRRAAAGLLPR-TASRASAWVRNPRGRER-IGTCGRRGLHVTANADAI-RHSHLNLHYLGQILNIKKQSVCVVHLRNSGTLGNPSSLDETAYERLAEETLDALAEFFEDLADKPYTLKDYDVSFGDGVLTIKLGGDLGTYVINKQTPLLYLWFSGPCSGPKRYDWTG----KNWVYSHDGVSLHELLARELTEALNTK-LDLSSLAYSGKGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35943-1", "uniprot_id": "FRDA_MOUSE", "id": "O35943-1", "name": "Frataxin, mitochondrial", "aln": "MWAFGGRAAVGLLPR-TASRASAWVGNPRWREP-IVTCGRRGLHVTVNAGAT-RHAHLNLHYL-QILNIKKQSVCVVHLRNLGTLDNPSSLDETAYERLAEETLDSLAEFFEDLADKPYTLEDYDVSFGDGVLTIKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTG----KNWVYSHDGVSLHELLARELTKALNTK-LDLSSLAYSGKGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16595-1", "uniprot_id": "FRDA_HUMAN", "id": "Q16595-1", "name": "Frataxin, mitochondrial", "aln": "MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAEL-APLCGRRGLRTDIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTG----KNWVYSHDGVSLHELLAAELTKALKTK-LDLSSLAYSGKDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NC77-1", "uniprot_id": "A0A8M1NC77_DANRE", "id": "A0A8M1NC77-1", "name": "Frataxin, mitochondrial", "aln": "MSRLTIKYCR-LYQLSLSSRWKCYQQISRLSTMSSGLNSISGGRSVSSANICGRHTQ----CFDRILN--KRDLHLSAPLGEEKAHHLREISEAEYERLAEETLDALADYFEDLTDENFTGLDYDVVFSNGVLTVKVGSDHGTYVINKQTPNRQIWLSSPTSGPKRYDWTG----ERWVYTHDAVPLHSLLSKELSIIFKTN-IDLSHLIHS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W385-1", "uniprot_id": "FRDA_DROME", "id": "Q9W385-1", "name": "Frataxin homolog, mitochondrial", "aln": "-------MFAGRLMVRSIVGRACLATMGRWSKPQAHASQVILPSTPAIAAVA----------------IQCEEFTANRRLFSSQIETESTLDGATYERVCSDTLDALCDYFEELTENASELQGTDVAYSDGVLTVNLGGQHGTYVINRQTPNKQIWLSSPTSGPKRYDFVGTVAAGRWIYKHSGQSLHELLQQEIPGILKSQSVDFLRLPYCS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07540-1", "uniprot_id": "FRDA_YEAST", "id": "Q07540-1", "name": "Frataxin homolog, mitochondrial", "aln": "-----------MIKRSLASLVRVSSVMGRRYMIAAAGGERARFCPAVTNKKN------------HTVNTFQKRFVESSTDGQVVPQEVLNLPLEKYHEEADDYLDHLLDSLEELSEAHPDCIP-DVELSHGVMTLEIP-AFGTYVINKQPPNKQIWLASPLSGPNRFDLLN----GEWVSLRNGTKLTDILTEEVEKAISKSQ-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : *.. ..: ** * : :*:*:: ** . **:*::: ******:*.* :*::.* ***:*:* . .*: :.. * .:* *: :... ", "identical_positions": 31, "similar_positions": 39, "identity": "14.35%" }, { "cls_id": "homologset.agr.SGD:S000002280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UN04-1", "uniprot_id": "UBP30_MOUSE", "id": "Q3UN04-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAQAARTAADKALQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTT--------------------------------------------------QYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHP----------TTNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEARGTLTGEKVEHQR----------------------------------------------STFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHE-HVQFN------------EFLMMDFYKYRLLGHKPSQHGPKATENPG--------------------------------------------------------------------------------------SAPEVQDAQAAPKPGLSQPGAPKTQIFLNGACSPSLLPALPSPVAFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSP-------------------PSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPG5-1", "uniprot_id": "UBP30_RAT", "id": "D3ZPG5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAQAARTAADKALQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTT--------------------------------------------------QYSRDQQGPHTHQCLSLTLLSLLKALSCQEVTEEEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHP----------TTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQR----------------------------------------------TTFVKQLKLGKLPQCLCIHLQRLSWSSQGTPLKRHE-HVQFN------------EFLMMDFYKYRLLGHKPSQHGPKATESPG--------------------------------------------------------------------------------------SALGVQDTQAAPKPGLSQPAAPKTQFFMNGACSPSLLPALPSPMAFPLPVAPDYSSSMYLFRLMAVVVHHGDMHSGHFVTYRRSP-------------------PSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70CQ3-1", "uniprot_id": "UBP30_HUMAN", "id": "Q70CQ3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "---MLSSRAEAAMTAADRAIQRFLR--TGAAVRYKVMKNWGVIGGIAAALAAG----------------------IYVIWGP------ITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTS--------------------------------------------------QYSRDQKEPPSHQYLSLTLLHLLKALSCQEVTDDEVLDASCLLDVLR--MYRWQISSFEEQDAHELFHVITSSLE--------DERDRQPRVTHLFDVHSLEQQSEITPKQITCRTRGSPHP----------TSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNGEKVEHQR----------------------------------------------TTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHE-HVQFN------------EFLMMDIYKYHLLGHKPSQHNPKLNKNPG--------------------------------------------------------------------------------------PTLELQDGPGAPTPVLNQPGAPKTQIFMNGACSPSLLPTLSAPMPFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSP-------------------PSARNPLSTSNQWLWVSDDTVRKASLQEVLSSSAYLLFYERVLSRMQHQSQECKSEE----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGT0-1", "uniprot_id": "UBP30_DANRE", "id": "A2BGT0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 30", "aln": "-------MPWCKQGTTDKLVREFLR--TGAAARNKMMKNWGVIGGIAAAMAAG----------------------VYVLWGP------ISDRRKKRKGMVPGLLNLGNTCFMNSLLQGLAACPSFIRWLEDFTS--------------------------------------------------QNSADRERTERETQLSRSLMQLLKALSSHDPGEDDVLDAGGLLEALR--LYRWHISSFEEQDAHELFHVLTSSLE--------EEQERQPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHP----------IPSLWRTRHPFHGRLTSYMACKRCEQQSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVECENCTKQQAGELVNGEVLESQR----------------------------------------------TTFVKQLKLG----------KRLTWSKEGSPIKRQE-HVQFT------------EYLSLDRYKHCSAAQ--SQQKTSRTNKAK--------------------------------------------------------------------------------------ASADPKDKAIAN--GVDSEHCNNNKPQSNGTFPSVFLHSPG--LSSQLNLTYDYSTSEYLFRLTAVLVHHGDMHSGHFITYRRCP-------------------AAPRGTSPFSSQWLWVSDDSVRKASLQEVLSSSAYLLFYER----MQRPG--LRVEE----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25037-1", "uniprot_id": "UBP1_YEAST", "id": "P25037-1", "name": "Ubiquitin carboxyl-terminal hydrolase 1", "aln": "MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIFGIVVFFYKKPDHLNYIVESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEATHKKNTRKGGKVYGKHKKKLNRKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDKPYFKTNSLLKAMSKSPRKNILLGYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIPTEQIDPNSILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLPNENIGSTLKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLFGQLKEFEKKPEGSIPEKLINAVKDRVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKNNSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFEDSEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINYARSFSTVP---ATPLTYSLRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVDEAEVLSTPGVFMLFYEYDFDEETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQGEGEEQEEGQEQMKFERTEDHRDISGKDVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *** . : . : :. : :* **.. : * * : :. :* *::.**:* ********:**.*::. ::.:*:: . . . :.: . :* :* **.**..: :. :.:. **..: : : .::::**:*:*: : :.** :: : * . : .:* . : . .* . :: *:.* :. : * :* .:. :::. *..***.:* * .:.*.: * .: ..* :. * *:.*: * *: * :: : **: :. :* :. . ::::: :* *. : : :* . :*: .. :. :: :.. . ..: .: : . : . :: : * :*:**:* : **::::*: :. . :: : .: * .*: : *.. *: :*. . * ", "identical_positions": 82, "similar_positions": 184, "identity": "10.1%" }, { "cls_id": "homologset.agr.SGD:S000002282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VC28-1", "uniprot_id": "AK1CD_MOUSE", "id": "Q8VC28-1", "name": "Aldo-keto reductase family 1 member C13", "aln": "MSSKQH-----CVKLNDGHLIPALGFGTYK-------------------------------------P------KEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSG-DNDFPVN-EQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRK--LLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQ-VFGFQLSPEDMKTLDGLNKNFRYLPAEFLVDHPEYPFVEEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AD50-1", "uniprot_id": "A0A8I6AD50_RAT", "id": "A0A8I6AD50-1", "name": "", "aln": "MAASCHYWAMALFKIQSSEYVNQISFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCSPGVSASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIKAGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKSG-DNDFPVD-EKGKSLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSK--LLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLVQRGVVPLAQSFKENEMRENLQ-VFDFQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPFSEEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9Y6-1", "uniprot_id": "G3X9Y6_MOUSE", "id": "G3X9Y6-1", "name": "", "aln": "MSSKQQ-----CVKLNDGNFIPALGFGTYK-------------------------------------P------EEVNENKPLEAIHLALEAGFRHIDTAYVYQTENHVGQAIRSKIAAGLVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQMKPG-EDLFPED-EHGKTLFDTVDICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQRK--LLNYCKSKDIVLVAYCALGSQRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALRYHLQRGIVVLAQSYKENEIKENIQ-VFEFELPSEDMKILDSLDRNLRYAPAPFGEGHPEYPFSDEF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51652-1", "uniprot_id": "AKC1H_RAT", "id": "P51652-1", "name": "Aldo-keto reductase family 1 member C18", "aln": "MNSKIQ-----KMELNDGHSIPVLGFGTYAT-------------------------------------------EENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPG-DELLPQD-EHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSK--LLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQ-VFDFQLASDDMEILDNLDRNLRYFPANMFKAHPNFPFSDEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZF77-1", "uniprot_id": "AK1CA_RAT", "id": "D3ZF77-1", "name": "Aldo-keto reductase family 1 member C15", "aln": "MDLKHSR----SVKLNDGNLMPVLGFGTFAS-------------------------------------------KEIPKSKAAEATKVAIDVGFRHIDAAYFYQNEEEVGQALRDKMADGTVKREDLFYTTKIWITFLRPELVRQCLERSLKKLGLDYVDLCIIHIPIAMKPG-EELLPKD-ANGKFIFDTVDIRDTWEALEKCKDAGLSKSIGVSNFNHKQLELILNKPRLKYKPTCNQVECHPYLNQSK--LLEFCKSKDIVLVAYSALGSHRDSSWVSSDSPYLLEDPVLMTIAKKHNQTPGQVALRYQLQRGVVVLAKSFNEKRIKENFQ-VFDFELTPEDMKTIDSLNRNFRYSQMAFALDHPDYPFLEEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJP0-1", "uniprot_id": "ALD1_RAT", "id": "Q5RJP0-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "MTT--------FVKLRTKAKMPLVGLGTWKS----------------------------------------------PPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAG-KEFLPKD-SQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK--LIQYCHSKGIAVIAYSPLGSP-DRPYAKPEDPVVLEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQ-VFDFQLSEEDMAAILSLNRNWRACGLFVTSDEEDFPFHEEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21300-1", "uniprot_id": "ALD1_MOUSE", "id": "P21300-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "MAT--------FVELSTKAKMPLVGLGTWKS----------------------------------------------SPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAG-NALLPKD-NKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEK--LIQYCQSKGIAVTAYSPLGSP-DRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQ-VFDFQLSEEDMAAILSFNRNWRACDLLDARTEEDYPFHEEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E895-1", "uniprot_id": "G5E895_MOUSE", "id": "G5E895-1", "name": "aldose reductase", "aln": "MAA--------FVTLLTGAKMPIVGLGTWKS----------------------------------------------PPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSG-NVFLPTD-DKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK--LIQYCHSKGITITAYSPLGSP-DRPSAKPEDPLLLEIPKIKEIAAKHKRTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQ-VFDFQLSEEDMAAILSFNRNWRACGLFAASHNEDFPFHAEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45377-1", "uniprot_id": "ALD2_MOUSE", "id": "P45377-1", "name": "Aldose reductase-related protein 2", "aln": "MAT--------FVELSTKAKMPIVGLGTWKS----------------------------------------------PPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPG-KELFPKD-DQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK--LIQYCHSKGISVTAYSPLGSP-DRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQ-VFDFQLSDEEMATILSFNRNWRACLLPETVNMEEYPYDAEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VTL0-1", "uniprot_id": "Q9VTL0_DROME", "id": "Q9VTL0-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "MSTP-------NFLLSNGKNMPMLGLGTWRS----------------------------------------------PPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLS--VAKLKPVVLQIECHPYLSQKP--LITLCYDNAIAVTAYSCLGSG-HTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFEPKAKVDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07551-1", "uniprot_id": "KAR_YEAST", "id": "Q07551-1", "name": "NADPH-dependent alpha-keto amide reductase", "aln": "MSFHQQ-----FFTLNNGNKIPAIAIIGTGTRWYKNEE----------------------------------TDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPEVGKALSLTEKP----RNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFVSKEV----------------NGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILK--VAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQPFFEY---VKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQN-LFSFDLTAEEVDKITELGLEHEPLRLYWNKLYGKYNYAAQKV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : :.: : * *.* : * .:* *: . *: :* . * . : :: .: .* :* ::* * : . :*. :*: . * : :*:*** ::: :*. : :* *:* :* : : * : * : ** **. . . : :: * :: . : :*: : .: : * . ..: : : :: *:*. ::: : :. : . .. : : ", "identical_positions": 37, "similar_positions": 87, "identity": "9.74%" }, { "cls_id": "homologset.agr.SGD:S000002283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62959-1", "uniprot_id": "HINT1_RAT", "id": "P62959-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----------------------------------------------------------MAD--EIAKAQVAQPGGD--TIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQ------MNWPPG----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70349-1", "uniprot_id": "HINT1_MOUSE", "id": "P70349-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----------------------------------------------------------MAD--EIAKAQVAQPGGD--TIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQ------MNWPPG----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49773-1", "uniprot_id": "HINT1_HUMAN", "id": "P49773-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----------------------------------------------------------MAD--EIAKAQVARPGGD--TIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ------MHWPPG----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0S9-1", "uniprot_id": "HINT2_MOUSE", "id": "Q9D0S9-1", "name": "Adenosine 5'-monophosphoramidase HINT2", "aln": "--------------------------MAAAVLLAVGLRAARRTLAAAGARGAQVRGNAGVSDGSEVAKAQKAAPGGASPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQAEEDDQQLLGHLLLVAKKIAQAQGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AB01-1", "uniprot_id": "D4AB01_RAT", "id": "D4AB01-1", "name": "", "aln": "MTCTTGPAPPAVTANGAAPAGDKLGKMAAAVLLAVGMRAAHRTLAAAGSRGAQVRGNAGMSDGSEVAKAQKAVPGGAAPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQAEEDDQQLLGHLLLVAKKIAQAEGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BX68-1", "uniprot_id": "HINT2_HUMAN", "id": "Q9BX68-1", "name": "Adenosine 5'-monophosphoramidase HINT2", "aln": "--------------------------MAAAVVLAAGLRAARRAVAATGVRGGQVRGAAGVTDGNEVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04344-1", "uniprot_id": "HNT1_YEAST", "id": "Q04344-1", "name": "Adenosine 5'-monophosphoramidase HNT1", "aln": "-------------------------------------------------------MEPLISAPYLTTTKMSAPATLDAACIFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYHGAKLHDIPD---EFLTDAMPIAKRLAKAMKLDT-YNVLQNNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. * . ** :*: .:*: : * . . .* *: * * * *:**: .:: : .:* . : :.*: * * *.:: *:* . *.* *:*:*:: *: : **. ", "identical_positions": 29, "similar_positions": 41, "identity": "13.36%" }, { "cls_id": "homologset.agr.SGD:S000002284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55072-1", "uniprot_id": "TERA_HUMAN", "id": "P55072-1", "name": "Transitional endoplasmic reticulum ATPase", "aln": "---------MASGADSKGDD-LSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNP--SAMEVEED----------DPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGS-FRFPSGNQGGAGPSQGSGGGTGGS------VYTEDNDDDLYG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01853-1", "uniprot_id": "TERA_MOUSE", "id": "Q01853-1", "name": "Transitional endoplasmic reticulum ATPase", "aln": "---------MASGADSKGDD-LSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNP--SAMEVEED----------DPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGS-FRFPSGNQGGAGPSQGSGGGTGGS------VYTEDNDDDLYG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46462-1", "uniprot_id": "TERA_RAT", "id": "P46462-1", "name": "Transitional endoplasmic reticulum ATPase", "aln": "---------MASGADSKGDD-LSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNP--SAMEVEED----------DPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGS-FRFPSGNQGGAGPSQGSGGGTGGN------VYTEDNDDDLYG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZU99-1", "uniprot_id": "TERA_DANRE", "id": "Q7ZU99-1", "name": "Transitional endoplasmic reticulum ATPase", "aln": "---------MASGGESKNDD-LSTAILKQKNRPNRLIVDESINEDNSVVSLSQAKMDELQLFRGDTVLLKGKKRRETVCIVLSDDTCSDEKVRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGVRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPNITWEDIGGLDDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNVGDGGGAADRVINQILTEMDGMSSKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRIAILKANLRKSPISKDVDLDFLAKMTNGFSGADLTEICQRACKLAIRESIENEIRRERERQTNP--SAMEVEED----------DPVPEIRKDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGS-FRFPSSNQGGSGPSQGSSGGGGGN------VFNEDNDDDLYG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KN62-1", "uniprot_id": "TERA_DROME", "id": "Q7KN62-1", "name": "Transitional endoplasmic reticulum ATPase TER94", "aln": "------------MADSKGED-LATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQN-SAMDMDED----------DPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFP----GQTGNTSGSGNNLPVN------SPGDNGDDDLYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25694-1", "uniprot_id": "CDC48_YEAST", "id": "P25694-1", "name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "aln": "MGEEHKPLLDASGVDPREEDKTATAILRRKKKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVKVEGEDVEMTDEGAKAEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNFNDAPLGTTATDNANSNNSAPSGAGAAFGSNAEEDDDLYS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :* :****::*.: * *:*::: *:****:::.. .**:*:*******::***:*:::* *** ** * *:******** ::*.*:::::.***:**..*: :*** :: **:*****:::*****:*****:: ** *:**..** :***** .:*. *.:** :*:*. :*:**:**:**:.:* ******** ***:***:********** ******:*****:*:**********:*******************:***:******************:********:*:*****:**:******:**********:* ::::*:**********************:************:*:******** ****** :* *:**:****:*:******:* **:*******::: *****: **.***::**:*: :*.********** : ** *:***:.:*.**:* *:*** ***:: ***: **:********* ********:*.* .*****:******:**:****:*:*:****** *** *:*:************.:**.***:***:**:*******.:*****:******** ****************:****:::* :**:*:***:*: ::* :** *:******* * ***.* **:::** . ::* *: : . ::: :: **** * ** ***: *:***** ::*:** ::* :: *** . *.* * :. ...... . : *****.", "identical_positions": 510, "similar_positions": 194, "identity": "61.08%" }, { "cls_id": "homologset.agr.SGD:S000002285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7B2-1", "uniprot_id": "CNPD1_RAT", "id": "Q6P7B2-1", "name": "Protein CNPPD1", "aln": "MDLAGLLLDEEGTFSLSGFQDFTFLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSSS--DLFLISMMVASKYLYDEGEEEEVFNDEWGAAGGVAVPTLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPMWQLSLGSLCQRLVKLSCLLAVAYVSSVALAVASMAVIHQSLGLSSSPSPSPPELTLVPKNLLQPCIPAPVPQCLT---NVSSCLEDSVELPSLWGSLLDPLTPPLMPPPDPPAPPTPFHKCPFCQKFQRNPPNCRACHQPNRTVSIGPIHPFYHTHGLAPPWLWSPVAPPFLQPQQCSLFSVMKLARLTSVIFPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K158-1", "uniprot_id": "CNPD1_MOUSE", "id": "Q8K158-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGAFSLTGFQDFMVLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSSS--DLFLISMMVASKYLYDEGEEEEVFNDEWGAAGGVAVATLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSSSPSPGPPELTLVSKSLVQPCVPAPVSQCLT---NVSSCLEGSVDLPSLWGSLLAPLTPPLRPPPDPPAPPTPLHKCPLCQKFQRLPPNCRACHT-NQTVSIGPSRPLYHARGLAPPWLWSPVAPPFLQPQQCSLFSVMELAHLKSVISPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV87-1", "uniprot_id": "CNPD1_HUMAN", "id": "Q9BV87-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGTFSLAGFQDFTFLPGHQKLSARIRRRLYYGWDWEADCSLEELSSPVADIAVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSSS--DLFLISMMVASKYLYDEGEEEEVFNDEWGAAGGVAVPTLNALERGFLSAMDWHLYTDPREIFEVLSWLESCVAEQQGRWRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSCIPTPGPPDLGLTSRCLLEPCIPS-VPQCLPSLANVSSCLEGSMGLRSLWGSLLASLTPPPLPPPDPPAPPTLLHNCHLCQKLQRDSPTCHACLHPNRTVPTALSSPWYHTYGLAPPWPWSPVLLSLPQPQQCSLFSVMELARLKSFVFPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25693-1", "uniprot_id": "PCL2_YEAST", "id": "P25693-1", "name": "PHO85 cyclin-2", "aln": "------------------MSNYEALLKFNRKAVSKEMVQYLASTTASIIKIKKTNS--------MIDIALPAPP---LTKFINRLIKHSNVQTPTLMATSVYLAKLRSIIPSNVYGIETTRHRIFLGCLILAAKTLNDSSPLNKHWAEYT--DGLLILREVNTIERELLEYFDWDVTISTDDLITCLSPFLKPIKEEQ-----LYKSQRDCRTLKN-------------------------FSAQEKDIVNKTSISHSRSSSNMSIPSLASTSTLS------------------------TLESRRSNLSNYSNRIR-------------TLPELHESNNISDKFSPRTYNIDSKHDNKENRPIPTIKPFNFSK--ARPVILKTGLNKQIIKEDTKVKKSNWSNYFKS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: * .:: :. . * . : .::: .* ::: * *:* .*:: :: :.: :.. ::* : **: :** *. : :.:: :** .:::*:* * *.. :: : : * : : :*::** :*. :** : .. ::: ** : . : *:* *. * *:: .*: :.. : * :* . * . *. .. . **. * :.. : : * .. :.:*:. . . : :.. . * .: * * .. :: .: . :.* ", "identical_positions": 47, "similar_positions": 120, "identity": "11.38%" }, { "cls_id": "homologset.agr.SGD:S000002288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05386-1", "uniprot_id": "RLA1_HUMAN", "id": "P05386-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSTAAAP--AEEKKVEAKKEE-SEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19944-1", "uniprot_id": "RLA1_RAT", "id": "P19944-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSAAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47955-1", "uniprot_id": "RLA1_MOUSE", "id": "P47955-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVSVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGAAPSTAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08570-1", "uniprot_id": "RLA1_DROME", "id": "P08570-1", "name": "Large ribosomal subunit protein P1", "aln": "MSTKAELACVYASLILVDDDVAVTGEKINTILKAANVEVEPYWPGLFAKALEGINVKDLITNIGSG-----VGAAPAGGAAPAAAAAAPAAESKKEEKKKEEESDQSDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10622-1", "uniprot_id": "RLA3_YEAST", "id": "P10622-1", "name": "Large ribosomal subunit protein P1B", "aln": "---MSDSIISFAAFILADAGLEITSDNLLTITKAAGANVDNVWADVYAKALEGKDLKEILSGFHN------AGPVAGAGAASGAAAAG--GDAAAEEEKEEEAAEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::::** * : :* ::: :: ***...*: *..::**** . :: .:: .. .*.....*.*..:*** .: * *:** :::*:*********", "identical_positions": 33, "similar_positions": 46, "identity": "28.21%" }, { "cls_id": "homologset.agr.SGD:S000002289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38060-1", "uniprot_id": "HMGCL_MOUSE", "id": "P38060-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "--MASVRKAFPRRLVGLTSLRAVS---------------------------------------------TSSMGTLPKQVKIVEVGPRDGLQNEKSIVPTPVKIRLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSVFGAVSELFTRKNANCSIEESFQRFAGVMQAAQAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVMHEVPVTALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLNGLGIHTGVNLQKLLEAGDFICQALN--------------------------------------------------RKTSSKVAQATCKL---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97519-1", "uniprot_id": "HMGCL_RAT", "id": "P97519-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "--MATVRKAFPQRLVGLASLRAAS---------------------------------------------TSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALN--------------------------------------------------RKTSSKVAQATCKL---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35914-1", "uniprot_id": "HMGCL_HUMAN", "id": "P35914-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "--MAAMRKALPRRLVGLASLRAVS---------------------------------------------TSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLG---GCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALN--------------------------------------------------RKTSSKVAQATCKL---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZS7-1", "uniprot_id": "HMGC2_MOUSE", "id": "Q8JZS7-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "--MGNLPSAAKHCLNYQQLLREHLWSGDSVAGALDAAQ------------------------------EASQLPGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMRGIRQYPGVRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFQEVISSARHMDIPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGMGLNTGVDLYKVMEAGEFICKAVN--------------------------------------------------KTTNSKVAQASFNARLE------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5C3-1", "uniprot_id": "HMGC2_RAT", "id": "D4A5C3-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "--MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQ------------------------------EASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVN--------------------------------------------------KTTNSKVAQASFKARLE------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB92-1", "uniprot_id": "HMGC2_HUMAN", "id": "Q8TB92-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "--MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQTSLLTNLHCFQPDVSGFSVSLAGTVACIHWETSQLSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVN--------------------------------------------------KTTNSKVAQASFNA---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WG57-1", "uniprot_id": "HMGC2_DANRE", "id": "A8WG57-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "--MGNVSSAVKHCLSYETFLRDYPWLPRLLWEEK-----------------------------------CSELPKLPVYVKIVEVGPRDGLQNEKEIVPTEVKIQLIDLLSQTGLPVIEATSFVSSKWVAQMADHTAVLKGIKRSPDVRYPVLTPNIQGFQAAVAAGANEVAVFGSASETFSRKNINCSIEESLQRFEQVVSAAKQEGIPVRGYVSCALGCPYEGQVKPSQVTKVAKRLFELGCYEVSLGDTIGVGTAGSMAEMLSDVLTEVPAGALAVHCHDTYGQALPNILIALQMGVSVVDASVAGLG---GCPFAKGASGNVSTEDLLYMLHGLGIETGVDLLKVMEAGDFICKALN--------------------------------------------------RKTNSKVSQATRNN---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM58-1", "uniprot_id": "Q9VM58_DROME", "id": "Q9VM58-1", "name": "hydroxymethylglutaryl-CoA lyase", "aln": "-----MISAPIRSILALTAKR-------------------------------------------------TAVTSAANQVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLG---GCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELG--------------------------------------------------RTSESKVNRAWKGPQARVK----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12122-1", "uniprot_id": "HOSM_YEAST", "id": "Q12122-1", "name": "Homocitrate synthase, mitochondrial", "aln": "MSENNEFQSVTESTTAPTTSNPYGPN-------------------------------------------PADYLSNVKNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLG----LKAKILTHIRCHMDDARVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIR------FSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIR-TLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVRSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKSRVDQLNLNLTDDQIKEVTAKIKKLGDVRPLNIDDVDSIIKDFHAELSTPLLKPVNKGTDDDNIDISNGHVSKKAKVTK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . : .:::: *:* * :. : **.: *.: *: ** ** *:.. : : : . : ::.. . *: :*. : :. ..*. : . . ::. .: .: * ... . : :: : . :* .:.:.**:* ... : :: . : : * *: * *:.* :*: * ::* :* *:* * . * .. . *: :.. :: ::: . : .. . .*:* : ", "identical_positions": 36, "similar_positions": 106, "identity": "7.29%" }, { "cls_id": "homologset.agr.SGD:S000002290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D4H8-1", "uniprot_id": "CUL2_MOUSE", "id": "Q9D4H8-1", "name": "Cullin-2", "aln": "--------MSLKPRVVDFDETWNKLLTTIKAVVM------------LEYVERATWNDRFSDIYALCVAYPEP------------------------LGERLYAETKIFLESHVRHLYKR--VLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTEADIQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHV-----EQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCR--------KYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIQQERKNDMANMYVLLRAVSSGLPHMIEELQKHIHDEGLRATSNLT-----------------------QEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVN----YREPKSV----CKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIRNQDTV-IDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGK---PYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDS-----EKEDIDAESSFSLNMSFSSKRTKFKITTSMQKDTPQ--------------------ELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0H4-1", "uniprot_id": "D4A0H4_RAT", "id": "D4A0H4-1", "name": "Cullin-2", "aln": "--------MSLKPRVVDFDETWNKLLTTIKAVVM------------LEYVERATWNDRFSDIYALCVAYPEP------------------------LGERLYAETKIFLENHVRHLYKR--VLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHV-----EQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCR--------KYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIRHERKNDMANMYVLLRAVSSGLPHMIEELQRHIHDEGLRATSNLT-----------------------QEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVN----YREPKSV----CKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIRNQDTV-IDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGK---PYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDS-----EKEDIDAESSFSLNMSFSSKRTKFKITTSMQKDTPQ--------------------ELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13617-1", "uniprot_id": "CUL2_HUMAN", "id": "Q13617-1", "name": "Cullin-2", "aln": "--------MSLKPRVVDFDETWNKLLTTIKAVVM------------LEYVERATWNDRFSDIYALCVAYPEP------------------------LGERLYTETKIFLENHVRHLHKR--VLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHV-----EQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCR--------KYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIHDEGLRATSNLT-----------------------QENMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVN----YREPKSV----CKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIKNQDTV-IDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGK---PYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDS-----EKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTPQ--------------------EMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P612-1", "uniprot_id": "A0A8M9P612_DANRE", "id": "A0A8M9P612-1", "name": "Cullin-2", "aln": "--------MSLKPRVVDFDETWNKLLTTIRAVVM------------LDYVERATWNDRFSDIYALCVAYPEP------------------------LGEKLYTETKVFLENHVRQLFKR--VLESEEKVLVMYHRYWEEYSKGAEYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMIEPLQPMLIGKLLKEIKNDRCGEDPNQKVIHGVINSFVHV-----EQYKKKFPLKFYQEIFEGPFLTKTGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEVRCR--------KYLHPSSYSKVIHECQQRMVADHLQFLHGECQNIIRQEKRDDMANMYTLLRAVSSGLPHMIQELQVHIHDEGIRATINLS-----------------------QENMPTLFVESVLEVHSKFVQLINTVLNGDQHFMSALDKALTSVVN----YREPKSI----CKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKIYARMLAKRLIHGLSLSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSTDLNNKFNNFIKTQETV-VDLGISFQIYVLQAGAWPLTHVPSSTFAIPQELEKSVQMFELFYNQHFSGRKLTWLHYLCTGEVKMNYLSK---PYVAVVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELQKTIKSLLDVKMISHDL-----QKEEIEPESTFSLIMSFTSKRTKFKITTSMQKDTPQ--------------------ELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVINQSKARFNPSISMIKKCIEVLIDKQYIERSQSSADEYSYVA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WTX6-1", "uniprot_id": "CUL1_MOUSE", "id": "Q9WTX6-1", "name": "Cullin-1", "aln": "MSSNRSQNPHG-LKQIGLDQIWDDLRAGIQQVYT------------RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRR----ECDEGR--------KGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCG---------------------EAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQQS--CTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13616-1", "uniprot_id": "CUL1_HUMAN", "id": "Q13616-1", "name": "Cullin-1", "aln": "MSSTRSQNPHG-LKQIGLDQIWDDLRAGIQQVYT------------RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRR----ECDEGR--------KGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCG---------------------EAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQQS--CTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5Y0H0-1", "uniprot_id": "A0A8I5Y0H0_RAT", "id": "A0A8I5Y0H0-1", "name": "Cullin-1", "aln": "MSSNRSQNPHG-LKQIGLDQIWDDLRAGIQQVYT------------RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRR----ECDEGR--------KGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCG---------------------EAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQQS--CTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKVPPSEAFPRRLPYSPQDVPGRRAQARG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24311-1", "uniprot_id": "CUL1_DROME", "id": "Q24311-1", "name": "Cullin homolog 1", "aln": "--MNRSGNSQTTQKLVNLDDIWSELVEGIMQVFEH-----------EKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSSGK----------TGGAQLVGKKLYDRLEQFLKSYLSELLTKFKAISGEEVLLSRYTKQWKSYQFSSTVLDGICNYLNRNWVKR----ECEEGQ--------KGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLINRSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEYLKHVENRLEEETQRVRGFNSKNGLSYLHETTADVLKSTCEEVLIEKHLKIFHTEFQNLLNADRNDDLKRMYSLVALSSKNLTDLKSILENHILHQGTEAIAKCCT--------------------TDAANDPKTYVQTILDVHKKYNALVLTAFNNDNGFVAALDKACGKFINSNVVT-IANSA----SKSPELLAKYCDLLLKKSSKNPEDKELEDNLNQVMVVFKYIEDKDVFQKYYSKMLAKRLVNHTSASDDAEAMMISKLKQTCGYEYTVKLQRMFQDIGVSKDLNSYFKQYLAEKN---LTMEIDFGIEVLSSGSWPFQLS--NNFLLPSELERSVRQFNEFYAARHSGRKLNWLYQMCKGELIMNVNRNNSSTYTLQASTFQMSVLLQFNDQLSFTVQQLQDNTQTQQENLIQVLQILLKAKVLTSSD-----NENSLTPESTVELFLDYKNKKRRININQPLKTELKV--------------------EQETVHKHIEEDRKLLIQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDILIEKEYLERMEGHKDTYSYLA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12018-1", "uniprot_id": "CDC53_YEAST", "id": "Q12018-1", "name": "Cell division control protein 53", "aln": "-------MSETLPRSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILSPTMYMEVYTAIYNYCVNKSRSSGHFSTDSRTG--------QSTILVGSEIYEKLKNYLKNYILNFKQS-----NSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQK----ERSDGK--------RHIFDVNTLCLMTWKEVMFDPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALG--IDPQDLKKLNLNVYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMT--------IYWDDHTKKPLSMALNKVLITDHIEKLENEFVVLLDARDIEKITSLYALIRRDFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKATKPEVASDMSD--EDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQ-EVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNFTVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPG---LDALVKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIEKELNTERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRGDD-GESYAYLA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: *. : * : . : : : :: :* *. . :* .:* . : :*:.:: .: ... . * : *: : .: :: *:* :::: * . . : .: *.* *: :. : : :* : * *: : : .::. * : : *..* * *: .* :* : : *. ::*: .. : * * . : : :: :: .*:: :. * :: :.: :* *: : : . :: :: . * . *. :::.:*:** : :. : .* : ***:* .:* . * .*:.*:**:*.* ****::* ::.* ..:.:***: ***.*:. * :::****:: * * : * :*.:*: : . *:* *: :*: *: :* *:. * : . .: ** . **: * :*.** * . : * :..** *.** :. **: : : .: :**::** :* : ::: :.*. . : .: ::. *:: . : .:: ..* :. : ..:: ::.: * * .. :: :*:: ::*.****** :: * * *: * : * **:. :.::* . : : : : ", "identical_positions": 125, "similar_positions": 249, "identity": "14.45%" }, { "cls_id": "homologset.agr.SGD:S000002292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63330-1", "uniprot_id": "PP2AA_MOUSE", "id": "P63330-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "--------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63331-1", "uniprot_id": "PP2AA_RAT", "id": "P63331-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "--------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYA4-1", "uniprot_id": "A0A0G2JYA4_RAT", "id": "A0A0G2JYA4-1", "name": "Serine/threonine-protein phosphatase", "aln": "--------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPTIDTLDHIGALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67775-1", "uniprot_id": "PP2AA_HUMAN", "id": "P67775-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "--------------------------------------------------MDEKVFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFZ9-1", "uniprot_id": "A0A8M1PFZ9_DANRE", "id": "A0A8M1PFZ9-1", "name": "Serine/threonine-protein phosphatase", "aln": "--------------------------------------------------MEEKAFAK----------ELDQWIEQLNECKQLSETQVKTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62715-1", "uniprot_id": "PP2AB_MOUSE", "id": "P62715-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "--------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62714-1", "uniprot_id": "PP2AB_HUMAN", "id": "P62714-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "--------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62716-1", "uniprot_id": "PP2AB_RAT", "id": "P62716-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "--------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23696-1", "uniprot_id": "PP2A_DROME", "id": "P23696-1", "name": "Serine/threonine-protein phosphatase PP2A", "aln": "--------------------------------------------------MEDKATTK----------DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23594-1", "uniprot_id": "PP2A1_YEAST", "id": "P23594-1", "name": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit", "aln": "MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :* :****:*:*.:*: *.* :* **. * ::* *.**: :. ***:***********:***:*** .**********************: ***:**** .*:***************************.***** *******:*:*****.:********** *:::*:: *:*:*******************************:*****:** **::*.*:*::********** *.*::********************:**:*:. : .***:**: * *** *:*:******", "identical_positions": 222, "similar_positions": 60, "identity": "60.16%" }, { "cls_id": "homologset.agr.SGD:S000002294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI73-1", "uniprot_id": "GDIR1_RAT", "id": "Q5XI73-1", "name": "Rho GDP-dissociation inhibitor 1", "aln": "-------------------------------------------MAEQEPTAEQLAQIAAENEEDEHSV-NYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVA---VSADPNVP-NVIVTRLTLVCSTAPGPLELDLT--GDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEE---YEFLTPMEEAPKGMLARGSYNIKSRFTDDDKTDHLSWEWNLTIKKEWKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PT1-1", "uniprot_id": "GDIR1_MOUSE", "id": "Q99PT1-1", "name": "Rho GDP-dissociation inhibitor 1", "aln": "-------------------------------------------MAEQEPTAEQLAQIAAENEEDEHSV-NYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVA---VSADPNVP-NVIVTRLTLVCSTAPGPLELDLT--GDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEE---YEFLTPMEEAPKGMLARGSYNIKSRFTDDDKTDHLSWEWNLTIKKEWKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52565-1", "uniprot_id": "GDIR1_HUMAN", "id": "P52565-1", "name": "Rho GDP-dissociation inhibitor 1", "aln": "-------------------------------------------MAEQEPTAEQLAQIAAENEEDEHSV-NYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVA---VSADPNVP-NVVVTGLTLVCSSAPGPLELDLT--GDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEE---YEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTIKKDWKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61599-1", "uniprot_id": "GDIR2_MOUSE", "id": "Q61599-1", "name": "Rho GDP-dissociation inhibitor 2", "aln": "-------------------------------------------MTEKD---AQPQLEEADD-DLDSKL-NYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDVP---VVADPTVP-NVTVTRLSLVCDSAPGPITMDLT--GDLEALKKDTFVLKEGIEYRVKINFKVNKDIVSGLKYVQHTYRTGMRVDKATFMVGSYGPRPEE---YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLTWEWNLAIKKDWTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZXI2-1", "uniprot_id": "A0A8I5ZXI2_RAT", "id": "A0A8I5ZXI2-1", "name": "", "aln": "MIRKVLTRLLGQKGEVSPGKGDKLKEVGESILLPECSREGTIKMTEKD---EQPQLEEGED-ELDSKL-NYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDVP---VVADPTVP-NVTVTRLSLVCDSAPGPITMDLT--GDLKALKKDTFVLKEGIEYRVKINFKVNKDIVSGLKYVQQTYRNGMKVDKATFMVGSYGPRPEE---YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLTWEWNLAIKKDWTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52566-1", "uniprot_id": "GDIR2_HUMAN", "id": "P52566-1", "name": "Rho GDP-dissociation inhibitor 2", "aln": "-------------------------------------------MTEKA---PEPHVEEDDDDELDSKL-NYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGP---VVTDPKAP-NVVVTRLTLVCESAPGPITMDLT--GDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE---YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62160-1", "uniprot_id": "GDIR3_MOUSE", "id": "Q62160-1", "name": "Rho GDP-dissociation inhibitor 3", "aln": "-----------------------MLGLDACELGEQLLELLRLALCARVLLADKDGESTPSDEVLDEIVPEYQAPGKKSMLAIWQLDPGDVSLVKYKQALLGPLP---PIMDPSLP-NVQVTRLTLLTEQAPGPIIMDLT--GDLDALKNQVFVLKEGIEYKVKITFKVNKEIVSGLKCLHHTYRRGLRVDKAIFMVGSYGPRAQE---YEFVTSVEEAPRGALARGLYVVRSLFTDDDRLNHLSWEWHLHVCQDWKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRJ5-1", "uniprot_id": "A0A8I5ZRJ5_RAT", "id": "A0A8I5ZRJ5-1", "name": "Rho GDP-dissociation inhibitor 3", "aln": "-----------------------MLGLDACELGAQLLELLRLALCARVLLADKDGEPTPSDEVLDEIVPEYRAPGKKSMLEIWQLDPGDVSLVKYKQALLGPLP---PIMDPSLP-NVQVTRLTLLTEHAPGPMVMDLT--GDLDALKNQVFVLKEGIEYKVKITFKVNKEIVSGLKCLHHTYRRGLRVDKATFMVGSYGPRAQE---YEFVTPVEEAPRGALARGLYVVRSLFTDDDRLNHLSWEWCLHVCQDWKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99819-1", "uniprot_id": "GDIR3_HUMAN", "id": "Q99819-1", "name": "Rho GDP-dissociation inhibitor 3", "aln": "-----------------------MLGLDACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIRQLDPDDRSLAKYKRVLLGPLP---PAVDPSLP-NVQVTRLTLLSEQAPGPVVMDLT--GDLAVLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE---YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW59-1", "uniprot_id": "Q9VW59_DROME", "id": "Q9VW59-1", "name": "Rho GDP-dissociation inhibitor 3", "aln": "-------------------------------------------------MAETETKHHPEHHDDDVHDANYQAPPEKTIEEIMAADQEDESLRRYKEALLGAAQTEKIIVEPNDPRKVIVKKLALVVEGRD-DMELDLT--GDLSQLKKQLFVIKEGVQYKVRIDFIVQREIVHGLKYVQKTSRLGVNVDKMKHMVGSYPPKKEI---QFYLTPAEEAPSGTFSRGTYSVSSVFTDDDKHIHLEWDWTFEIKKDWA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12434-1", "uniprot_id": "GDIR_YEAST", "id": "Q12434-1", "name": "Rho GDP-dissociation inhibitor", "aln": "---------------------------------------------------MAEESTDFSQFEEERNNDQYKVSAKKTVDEYKNLDAEDESLAKWKESLGLSSD-VLPLEFPGDKRKVVVQKIQLLVNTEPNPITFDLTNEKTIKELASKRYKIKENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIAVDKIDDHLGSYAPNTKTKPFYEVELPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWGVEIVKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :*: . .*:: * * ** ::*. * * :* * : *: . : :*** : : .. :**. *:::* * *:::*: *:: :: : *: :** :*** * : . .*** * : ** * * * ***: ** :* . : :. ", "identical_positions": 45, "similar_positions": 48, "identity": "17.51%" }, { "cls_id": "homologset.agr.SGD:S000002295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWV7-1", "uniprot_id": "RL35_MOUSE", "id": "Q6ZWV7-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17078-1", "uniprot_id": "RL35_RAT", "id": "P17078-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42766-1", "uniprot_id": "RL35_HUMAN", "id": "P42766-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHJ1-1", "uniprot_id": "RL35_DANRE", "id": "Q8JHJ1-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAIRRQLTKHEENLMTKKMQRKSRLYSIR----------KFAVKA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M6G3-1", "uniprot_id": "F1M6G3_RAT", "id": "F1M6G3-1", "name": "Large ribosomal subunit protein uL29", "aln": "-----GSDLRGKKEEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVNSQTQKENLRKFFKGKKYKPLDLRPKKTGAMRRRLTKHEEKLKTKKQQWKERLYPLRTSTQSRTERMTMTIKCETDGKKKKKKEQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LHE8-1", "uniprot_id": "A0ABK0LHE8_RAT", "id": "A0ABK0LHE8-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLPSKEKEELLKQLEDLKVELSQLCVSKVTGGAASKLSKTGVIRKCSACVLTVINQTQEESLRKFYKGEKYKPLDLPPKKT--THRWLTKQEEELKTKKQQQKEWLYPLR----------RCAVEA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W499-1", "uniprot_id": "Q9W499_DROME", "id": "Q9W499-1", "name": "Large ribosomal subunit protein uL29", "aln": "MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQR----------KFAVKA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX85-1", "uniprot_id": "RL35B_YEAST", "id": "P0CX85-1", "name": "Large ribosomal subunit protein uL29B", "aln": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLS---RPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQR----------KYAIKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.:::* .** :** ** .* * *:: ..*.* .:**. * * * : *.* :*:.:*.:**:* ** *** :: *. : . * * * :. * :::. ", "identical_positions": 36, "similar_positions": 36, "identity": "24.66%" }, { "cls_id": "homologset.agr.SGD:S000002296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSL7-1", "uniprot_id": "ARF2_MOUSE", "id": "Q8BSL7-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84082-1", "uniprot_id": "ARF2_RAT", "id": "P84082-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84077-1", "uniprot_id": "ARF1_HUMAN", "id": "P84077-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84079-1", "uniprot_id": "ARF1_RAT", "id": "P84079-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84078-1", "uniprot_id": "ARF1_MOUSE", "id": "P84078-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61205-1", "uniprot_id": "ARF3_MOUSE", "id": "P61205-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61204-1", "uniprot_id": "ARF3_HUMAN", "id": "P61204-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61206-1", "uniprot_id": "ARF3_RAT", "id": "P61206-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P61750-1", "uniprot_id": "ARF4_MOUSE", "id": "P61750-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61751-1", "uniprot_id": "ARF4_RAT", "id": "P61751-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18085-1", "uniprot_id": "ARF4_HUMAN", "id": "P18085-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW4-1", "uniprot_id": "Q7ZUW4_DANRE", "id": "Q7ZUW4-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFGRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5M5-1", "uniprot_id": "Q6P5M5_DANRE", "id": "Q6P5M5-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*: *:*:*:*********.*****:********::*************:****.**********:**.**:**::**:*:***:*****.*: * : :** ***::** *:*.******:** :*:*:****:*:* * *::*:****.* ******:**:*:* : ", "identical_positions": 117, "similar_positions": 41, "identity": "64.29%" }, { "cls_id": "homologset.agr.SGD:S000002297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYT-SPALVSMTDR--TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILA-TAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQN--------------TCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGG-FFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHG-----AFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYT-SPALVSMTDR--NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILA-TAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRN--------------TMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGG-FFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHG-----AFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKAS------------------DNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWT-SPAETEIVDRG-EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLF-LVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRET-KANKVN--------------VWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGG-----TFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPZ9-1", "uniprot_id": "Q8IPZ9_DROME", "id": "Q8IPZ9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSTGGDK------------------------------------------------------------------------------------------------------------------------------------------------------------------YQYLAAISVNIISISYGAFCGWP-SSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFLFTWLADRIGRKLCLMW-MALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFN-------YAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGT-YSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHG-----TVFMFASLSFLAAIFIAIFVPETKGKSVDAILASL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12300-1", "uniprot_id": "RGT2_YEAST", "id": "Q12300-1", "name": "High glucose sensor RGT2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MNDSQNCLRQREENSHLNPGNDFGHHQGAECTINHNNMPHRNAYTESTNDTEAKSIVMCDDPNAYQISYTNNEPAGDGAIETTSILLSQPLPLRSN-------------------------------------------------------------------------------------------------------------------------------------------------VMSVLVGIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQIAILVSFLSLGTFFGALIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVVPLYQAEAAQKNLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRIPIGLQYVWSSILAVGMIFLPESPRYYVLKDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEASFG-------PSTLLDCFKTSENRPKQILRIFTGIAIQAFQQASGINFIFYYGVNFFNNTG-VDNSYLVSFISYAVNVAFSIPGMYLVDRIGRRPVLLAGGVIMAIANLVIAI----VGVSEGKTVVASKIMIAFICLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYFAVYETRGLTLEEIDELFRKAPNSVISSKWNKKIRKRCLAFPISQQIEMKTNIKNAGKLDNNNSPIVQDDSHNIIDVDGFLENQIQSNDHMIAADKGSGSLVNIIDTAPLTSTEFKPVEHPPVNYVDLGNGLGLNTYNRGPPSIISDSTDEFYEENDSSYYNNNTERNGANSVNTYMAQLINSSSTTSNDTSFSPSHNSNARTSSNWTSDLASKHSQYTSPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :..: . .: * . * : . . . : . : *. : : : **: :: .: :. : : : .*.: * * *:* .* . ::** : .:*::. . . : : . : : ::**:* . . :.* ::: : *. : * . . . : .:.: *:* .* :: * :* ::. ::: ::. : . :::: **: :* .. : : : :. . . : :: : : : : : ::: .*: . ::. . : : *: . : . . .:::..: .:. :.: : * **:* ::: * : ", "identical_positions": 35, "similar_positions": 148, "identity": "3.26%" }, { "cls_id": "homologset.agr.SGD:S000002299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24928-1", "uniprot_id": "RPB1_HUMAN", "id": "P24928-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08775-1", "uniprot_id": "RPB1_MOUSE", "id": "P08775-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5A6-1", "uniprot_id": "D4A5A6_RAT", "id": "D4A5A6-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDVTRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPEDSDEEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04052-1", "uniprot_id": "RPB1_DROME", "id": "P04052-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "----MSTPTDSKAPLRQVKRVQFGILSPDEIRRMSVTEGGVQFAETMEG--GRPKLGGLMDPRQGVIDRTSRCQTCAGNMTECPGHFGHIDLAKPVFHIGFITKTIKILRCVCFYCSKMLVSPHNPKIKEIVMKSRGQPRKRLAYVYDLCKGKTICEGGEDMDLTKENQQP----DPNKKPGHGGCGHYQPSIRRTGLDLTAEWKHQ---NEDSQEKKIVVSAERVWEILKHITDEECFILGMDPKYARPDWMIVTVLPVPPLAVRPAVVMFGAAKNQDDLTHKLSDIIKANNELRKNEASGAAAHVIQENIKMLQFHVATLVDNDMPGMPRAMQKSGKPLKAIKARLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPELVTPFNIDRMQELVRRGNSQYPGAKYIVRDNGERIDLRFHPKSSDLHLQCGYKVERHLRDDDLVIFNRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPRQIITPQANKPVMGIVQDTLTAVRKMTKRDVFITREQVMNLLMFLPTWDAKMPQPCILKPRPLWTGKQIFSLIIPGNVNMIRTHSTHPDEEDEGPYKWISPGDTKVMVEHGELIMGILCKKSLGTSAGSLLHICFLELGHDIAGRFYGNIQTVINNWLLFEGHSIGIGDTIADPQTYNEIQQAIKKAKDDVINVIQKAHNMELEPTPGNTLRQTFENKVNRILNDARDKTGGSAKKSLTEYNNLKAMVVSGSKGSNINISQVIACVGQQNVEGKRIPYGFRKRTLPHFIKDDYGPESRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIKAMESVMVNYDGTVRNSVGQLIQLRYGEDGLCGELVEFQNMPTVKLSNKSFEKRFKFDWSNERLMKKVFTDDVIKEMTDSSEAIQELEAEWDRLVSDRDSLRQIFPNGESKVVLPCNLQRMIWNVQKIFHINKRLPTDLSPIRVIKGVKTLLERCVIVTGNDRISKQANENATLLFQCLIRSTLCTKYVSEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTAIYYDPDPQRTVISEDQEFVNVYYEMPDFDPTR----ISPWLLRIELDRKRMTDKKLTMEQIAEKINVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLSDMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDPIRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAITRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLLLDAEKCRFGIEIP-NTLGNSMLGGAAMFIGGGSTPS--MTPPMTPWANCNTPRY-FSPPGHVSAMTPGGPSFSPSAASDASGMSPSWSPAHPGS--SPSSPGPSMSPYFPASP-SVSPSYSPTSPNYTASSPGG-----------------ASPNYSPSSPNYSPTSPLY--ASPRYASTTPNFNPQSTGYSPSSSGYSPTSPVYSPTVQFQS--SPSFAGSGSNIYSPGNAYSPSSSNYSPNSPSYSPTSPSYSPSSPSYSPTSPCYSPTSPSYSPTSPNYTPVTPSYSPTSPNYS-ASPQYSPASPAYSQTGVKYSPTSPTYSPPSPSYDGS---------------------------------PGSPQYTPGSPQYSPASPKYSPTSPLYSPSSPQHSPSN-QYSPTGSTYSATSPRYSPNMSIYSPSSTKYSPTSPTYTPTARNYSPTSPMYSPTAP--SHYSPTSPAYSPSSPTF---------EESED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04050-1", "uniprot_id": "RPB1_YEAST", "id": "P04050-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "----MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAK--IRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIK--DSKKRFAAIWTLCKTKMVCETDVPSE-----------DDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIP--------NGIHLQRFDEG-TTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVR------PKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMK-----YDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVK------------------------YMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSN----------------DAMAGG-FTAYG-------------------------------------------GADYGEATSPFG---------AYGEAPTSPGFGVSSPGFSPTSPTYSPTSP----------------------------AYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS-------------------------------------------------YSPTSPAYSPTSPSYSPTSP--------------SYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*** :*.****::**:*:: :**:: :::.** : *.*:*** *** * *:*. :**** .*.*********:*******:**:.* *: .***:.*.*:*:. :* ::: : . :.:**:: :: *** * :** . : * .: .:****. ** **: **.* ..**: .: .: : ::*.*.: :*:*:*: :: **:: ::**:***:* ***** .***:: : : :.:****.**:**:* * .*. * .**. *.* * .:******* :**::.* *:*:****:*:*::: ********:*****************: **** :******:*** .:*:.*:***:****: :***.* .::*****::**.*:*****: :..*::** *:*****: *.* *:*****:*******.***:::*:****:*** *:**************:*** *****:.:: .* *::**:*:* ******** .:**:* **.*: :*:*:* ::. **. :* *.*:**:***:****:*: ** :. * : *.* . :** *. ::: .*::*:*:: **::*:* *.*:*: * * :: ::.***.*:* *** :*.: ****:*** * .:* ::* :**..*::* ::*: * .. * ***::**::* *:**:****:* *: .*.: **.* **::*:*** ***:*: * ****.******.:** .****** ****.***:******** **** **:***************************:*::*.:**:** *.***:.:::*: *****: . :* *.: *: *: :***:::.* * : .:: .. . *: *:.:: .**. ** :* *::: ** *: *:* *.*: ***: *:** :: *** * :. ::: *.: : ::*:.:*. ** :** *.:: : :*:**: :**:*::.:**::* :: .:******.*****:*************:***::*:** *******::*::*: *:*****:* * * *:** : . :*****:.** : *****:*: **:.**:* :::::.: * : : ******:**** *.*:.*** *:.*:*: * :** *:.:** :**::* *::. .. :. : ::* :*: ** .** ::**:*:* * :* * .: : : **: **:*****..: .*:: .:** * :*.: :*: ****** * :: :*: *: * ******:*** *.** :* * ::****.**.:**.**:*******::*::*.* .* * :*****:::**:. ***.**:::* *. * :: ** . . . *** . *.:. . .* :.* ...*. ::. :. : :.*:*.:. *..:**:*. ****** :***:*..***.*************:*********.******.******.*:*.:********.** :**.*:*:** ** *. .******:***.*** *:*:** ****** ***:** .**.*** ***. . *:*:*.:******:*:**: *** ** ***. . . .. ", "identical_positions": 831, "similar_positions": 527, "identity": "41.97%" }, { "cls_id": "homologset.agr.SGD:S000002300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA38-1", "uniprot_id": "D4AA38_RAT", "id": "D4AA38-1", "name": "", "aln": "---------------------------------------MCLAREAARLALQGTGSSGSRLQGQAAAWRRVPEARAAWRSAHSRALLAAAARGRSGVSARPPCRAGGRAPGYESVDDLNKWALFLVSPFILEAEHIAFVTESIWVQGTSFQEPSSSETVVKWSDCCLPLACRPGDPYQLIAKASVDNFSKLGVAFMEDRLQMDNGLIAQKIVSVHLKDP---------------------------------------ALKELS-KASNKQVQAPLPSPEASLEAQPA---------------------QGVMEQAGQGDWKAAGEGPSPQRRGCAPVSESAADGDPGQG--------------STELCQLHLSSCHECLELENSTIESVRCASAEN------------IPDLPHDCSSSVEGTAGELCPE-----------RKGKRVNISGKAPNILLYVGSGSEEALGQLQQVRSVLTDCVDTDSYTLYHLLEDSALRDPWPDNCLLLVIASRDPIPKGIHHRFMAYLSQGGKVLGLSSSFTFGDLRVARRDVLRN---------------TAQNLVFSKADGSEVRLSVLSSGYVYEEGP----------SLGRLQGHLENEDKDKMIVHVPFGTH----------GGEAILCQVHLELPPSAPLVQTTDDFNVLKSSNTRRLEVLKEIL-------TALGLSCDAPQAPALTPLYLLLAAEEIQGPFMQWLARHVD-PEGVIKSSKLSLKFVSSYTSEAEITPSSIPVVTDPEGFSSEHFNLETYRQNLQST-RLGRVILFAEVTSTTMSLLDG--LMFEMPQEMGLIAIAVRQTQGKGRGPNAWLSPVGCALSTLLVSIPLRSQLGQR---IPFVQHLMSLAVVEAVRS-IPEYEDINLRVKWPNDIYYSD-----------------------------LMKIGGVLVNSTLVGETFYILIGCGFNVTNSNPTICIN---DLIEEHNKQN-KAGLKPLQADCLIARAVTVLEKLIDRFQDQGPDGVLPLYYKYWAHSGQ--QVRLGSSEGPAVSIVGLDD-SGFLQVHQEG--------GGVVSVHPDGNSFDMLRNLIVPKRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920N2-1", "uniprot_id": "BPL1_MOUSE", "id": "Q920N2-1", "name": "Biotin--protein ligase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDRLQMDNGLIAQKIVSVHLKDP---------------------------------------ALKELG-KASDKQVQGPPPGPEASPEAQPA---------------------QGVMEHAGQGDCKAAGEGPSPRRRGCAPESEPAADGDPGLS--------------SPELCQLHLSICHECLELENSTIDSVRSASAEN------------IPDLPCDHSG-VEGAAGELCPE-----------RKGKRVNISGKAPNILLYVGSGSEEALGRLQQVRSVLTDCVDTDSYTLYHLLEDSALRDPWSDNCLLLVIASRDPIPKDIQHKFMAYLSQGGKVLGLSSPFTLGGFRVTRRDVLRN---------------TVQNLVFSKADGTEVRLSVLSSGYVYEEGP----------SLGRLQGHLENEDKDKMIVHVPFGTL----------GGEAVLCQVHLELPPGASLVQTADDFNVLKSSNVRRHEVLKEIL-------TALGLSCDAPQVPALTPLYLLLAAEETQDPFMQWLGRHTD-PEGIIKSSKLSLQFVSSYTSEAEITPSSMPVVTDPEAFSSEHFSLETYRQNLQTT-RLGKVILFAEVTSTTMSLLDG--LMFEMPQEMGLIAIAVRQTQGKGRGPNAWLSPVGCALSTLLVFIPLRSQLGQR---IPFVQHLMSLAVVEAVRS-IPGYEDINLRVKWPNDIYYSD-----------------------------LMKIGGVLVNSTLMGETFYILIGCGFNVTNSNPTICIN---DLIEEHNKQH-GAGLKPLRADCLIARAVTVLEKLIDRFQDQGPDGVLPLYYKYWVHGGQ--QVRLGSTEGPQASIVGLDD-SGFLQVHQED--------GGVVTVHPDGNSFDMLRNLIVPKRQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50747-1", "uniprot_id": "BPL1_HUMAN", "id": "P50747-1", "name": "Biotin--protein ligase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDRLHMDNGLVPQKIVSVHLQDS---------------------------------------TLKEVKDQVSNKQAQILEPKPEPSLEIKPE---------------------QDGMEHVGRDDPKALGEEPK-QRRGSASGSEPAGDSDRGGG--------------PVEHYHLHLSSCHECLELENSTIESVKFASAEN------------IPDLPYDYSSSLESVADETSPE-----------REGRRVNLTGKAPNILLYVGSDSQEALGRFHEVRSVLADCVDIDSYILYHLLEDSALRDPWTDNCLLLVIATRESIPEDLYQKFMAYLSQGGKVLGLSSSFTFGGFQVTSKGALHK---------------TVQNLVFSKADQSEVKLSVLSSGCRYQEGPV-------RLSPGRLQGHLENEDKDRMIVHVPFGTR----------GGEAVLCQVHLELPPSSNIVQTPEDFNLLKSSNFRRYEVLREIL-------TTLGLSCDMKQVPALTPLYLLSAAEEIRDPLMQWLGKHVD-SEGEIKSGQLSLRFVSSYVSEVEITPSCIPVVTNMEAFSSEHFNLEIYRQNLQTK-QLGKVILFAEVTPTTMRLLDG--LMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQR---IPFVQHLMSVAVVEAVRS-IPEYQDINLRVKWPNDIYYSD-----------------------------LMKIGGVLVNSTLMGETFYILIGCGFNVTNSNPTICIN---DLITEYNKQH-KAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQ--QVHLGSAEGPKVSIVGLDD-SGFLQVHQEG--------GEVVTVHPDGNSFDMLRNLILPKRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LGM5-1", "uniprot_id": "A0A0B4LGM5_DROME", "id": "A0A0B4LGM5-1", "name": "", "aln": "MLTLYYVSATVLQSWRIQKACSKIAEHLAQPSSIAFYTLQSGSDDGFDPALASSELCCNRNAAKVTDILWLHANQRGCCLRPLQTLHITPWISFPPAPSLLPFSYAADTLTPASTPTEADVPRQQRVSLSAQGEERMQLLLEADIEPLQRPSSEDTSAVRLEDYGKLIAWKIDSHLAVLIETDVEHFTKLLITTFLRNNLCINDQLPLLRIESVQREGDPQPFELLAKHLKRQSRISVGLDKDGWKKHMEDLRAVGVLAHQATEFEYQRNRSEGRTKSDPTTHDQRPTSELLAKAVAVVEPTNKAYLSPARTTEASLKAEAKGTSTKPFPTKSDAKPATLAKSEGTPATSKEDSKLTPTKGALKTSELEKLAAVQAAQQQKKEAVQVSPVKAAFLAKPPMLSKHDEPDKASDQPTKPRKSFEAVKPLNSPPSSRAAPSRPVLQRNKDSLQDAKPLNVLVYSDSASARES-----TLATLQQLLERNVYTIYPLMPQQAAQKYWTEQTALLVVCG--SVAHGIGQILVDYFLQGGKVLSLCSDILHFVLPNYRTAEVREHELVQFSYDKWQRVKMMHHIFCYQPSPVKKHFSTDSEESTKSHSRKPALVCPRSMELKDLAGHSHNLDVHVLGTEETWNTPSLMLAKSLQSGGKAVFSQVHLEMNPSE-FESDETKYSILKQNERTRLEIFADLLGKYLDVQVRGGDGVDQPQPGVVYKHAYFLGRHEAKFELLEKLRLRCSGSDNVIATPNLTMKFCGKDDKPPVANNNVLPILIHS---CPDDFSTVDYFDNLKTE-HIGRLVIYAPVVSSSMHLIN------NLELIHGLAVLPVQQTSGVGRRNNQWLSPPGCAMFSLQLHLTMDSALSSR---LPLLQHLVGTAIVNSLRS-HEEYGVLDISIKWPNDIYANG-----------------------------NQKIGGLVINTTLQGSQAIVNIGSGINLNNSRPTVCIN---DLIREYNTRVPNNKLPILKYELLIAMIFNEIERLLGEVQNGDFDSFYALYYSLWLHSGQSVKICLQKDQEKEAEIVGIDD-FGFLEVKLPT--------GTIEIVQPDGNSFDMLKGLIIPKYQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48445-1", "uniprot_id": "BPL1_YEAST", "id": "P48445-1", "name": "Biotin--protein ligase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNVLVYNGPGTTPGSVKHAVESLRDFLEP------------------------YYAVSTVNVKVLQTEPWMSKTSAVVFPGGADLP--------------------------YVQACQPIISRLKHFVSKQGGVFIG------------------FCAGGYFGTSRVEFAQ--------------GDPTMEVSGSRDLRFFPGTSRGPAYN-------GFQYNSEAGARAVKLNLPDGSQFSTYFNGGAVFVDADK---------------FDNVEILATYAEHPDVPSSDSGKGQSEN----------------PAAVVLCTVGRGKVLLTGPHPEFNVRFMR------------KSTDKHFLETVVENLKAQEIMRLK----------FMRTVLTKTGLNCNNDFNYVRAPNLTPLFMASAPNKRNYLQEMEN----------NLAHHGMHANNVELCSELNAETDSFQFYRGYRASYDAASSSLLHKEP--DEVPKTVIFPGVDEDIPPFQYTP------NFDMKEYFKYLNVQNTIGSLLLYGEVVTSTSTILNNNKSLLSSIPESTLLHVGTIQVSGRGRGGNTWINPKGVCASTAVVTMPLQSPVTNRNISVVFVQYLSMLAYCKAILSYAPGFSDIPVRIKWPNDLYALSPTYYKRKNLKLVNTGFEHTKLPLGDIEPAYLKISGLLVNTHFINNKYCLLLGCGINLTSDGPTTSLQTWIDILNEERQQLHLDLLPAIKAEKLQALYMNNLEVILKQFINYGAAEILPSYYELWLHSNQ--IVTLPDHGNTQAMITGITEDYGLLIAKELVSGSSTQFTGNVYNLQPDGNTFDIFKSLIAKKVQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : * * : .. . . . :. . . . . . . :: .: .: : : . : : : : . : : ::* . :. ::*. : .: :. . : :: * : . : .. .::: :. *: . :: . : : : :: . . : . . ... : : . . *. .*. * . *: :* ::::. *..:: ::: . * : . *..* ** * *:.* * . : : :.: * : .* : ::*:* * ::: * : : : :*****:* . **.*:::*: : .. : :*.*:*:... ** .:: *:: * . : * :: : * * .. :* :: .. : . . . ** * *..* : * . . *.*: : *:* .: * : ::****:**:::.** * ", "identical_positions": 68, "similar_positions": 188, "identity": "6.12%" }, { "cls_id": "homologset.agr.SGD:S000002301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2V5-1", "uniprot_id": "CRLS1_RAT", "id": "Q5U2V5-1", "name": "Cardiolipin synthase (CMP-forming)", "aln": "MLAWRVARGAWGSLRVAVRPPGARLGRGGS------RRALLPPAACCLGCLAERWRLRPAAFALRLPGTSPRTHCSGAGKAAPEPAAGG-------------DAAAQAPSARWVRASATSSYENPWTIPNLLSMTRIGLAPVLGYLILEEDFNVALGVFALAGLTDLLDGFIARNWANQKSALGSALDPLADKVLISILYISLTYAD---LIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPR----TLAKYFNPC-YATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCCTAFTTAASAYSYYHYGRKTVQVIKGK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZM8-1", "uniprot_id": "CRLS1_MOUSE", "id": "Q80ZM8-1", "name": "Cardiolipin synthase (CMP-forming)", "aln": "MLAWRVARGAWGPLRVALRPPGARLGRGGS------RRALLPPAACCLGCLAERWRLRPAAFALRLPGAGPRTHCSGAGKAAPEPAAGGG------------GAAAQAPSARWVPASAASSYENPWTIPNLLSMTRIGLAPVLGYLILEEDFNVALGVFALAGLTDLLDGFIARNWANQKSALGSALDPLADKVLISILYISLTYAD---LIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPR----TLAKYFNPC-YATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCCTAFTTAASAYSYYHYGRKTVQVIKGK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJA2-1", "uniprot_id": "CRLS1_HUMAN", "id": "Q9UJA2-1", "name": "Cardiolipin synthase (CMP-forming)", "aln": "MLALRVARGSWGALRGAAWAPGTRPSKRRA------CWALLPPVPCCLGCLAERWRLRPAALGLRLPGIGQRNHCSGAGKAAPRPAAGA-------------GAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYAD---LIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPR----TLAKYFNPC-YATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MZC4-1", "uniprot_id": "CRLS1_DROME", "id": "Q8MZC4-1", "name": "Probable cardiolipin synthase (CMP-forming)", "aln": "MLPAIIFRQVQRPLHHGAATLEHVLGVGGSSFVNCLNRYAAATGFIRISFLDIKRRRNYELARLRLYADEKKQSLHLRTLQGRHLLQGVIERKNFLVDDIREARHKVQERVREKIDEIREERENIMTIPNMLTISRAVLSPYIGYVIVQGDFTLGMSLLAFAGITDLLDGQIARRWPSQASKFGSFLDPMADKLLMGSLVISLCYTD---LLPMWLMGIVVFRDVFLLGAGFVIRYISLPPPK----TFSRYFDAT-HVTAQLEPTLLSKINTGVQLATIGLSLGAPIWNYLDHPALQGLWYLTGLTTAATALSYVMNRHNTFKIIQKKT------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07560-1", "uniprot_id": "CRLS1_YEAST", "id": "Q07560-1", "name": "Cardiolipin synthase (CMP-forming)", "aln": "MIQMVPIYSCSALLRRTIPK---------------------RPFYHVLSGLTVRFKVNPQLNYNLFRDLTRREYATNP-------------------------------------SKTPHIKSKLLNIPNILTLSRIGCTPFIGLFIITNNLTPALGLFAFSSITDFMDGYIARKYG-LKTIAGTILDPLADKLLMITTTLALSVPSGPQIIPVSIAAIILGRDVLLAISALFIRYSTLKLKYPGRVAWNSYWDIVRYPSAEVRPSQLSKWNTFFQMVYLGSGVLLLLYEKEEGCEKTEEDFEDRKQDFQKAFSYLGYVTATTTIMSGVSYALKRNAFKLLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: . :. * : : . : : . .: .***:*:::* :* :* .*: ::. .:.::*::.:**::** ***.: : *: ***:***:*: ::* .. ::*: : ::: ***:* : : :** :* : *:: : :*.:.*: :** ** .*: :. .: ::: : .* ** * ::. ", "identical_positions": 48, "similar_positions": 83, "identity": "14.04%" }, { "cls_id": "homologset.agr.SGD:S000002302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPB1-1", "uniprot_id": "TCPD_RAT", "id": "Q7TPB1-1", "name": "T-complex protein 1 subunit delta", "aln": "MPENVASRSGPPAAGPGNRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANS--GITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDIEREDIEFICKTIGTKPVAHIDQFTPDMLGSAELAEEVSLNGSGKLFKITGCTS--PGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P80315-1", "uniprot_id": "TCPD_MOUSE", "id": "P80315-1", "name": "T-complex protein 1 subunit delta", "aln": "MPENVASRSGAPTAGPGSRGKSAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANS--GITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNGSGKLFKITGCTS--PGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50991-1", "uniprot_id": "TCPD_HUMAN", "id": "P50991-1", "name": "T-complex protein 1 subunit delta", "aln": "MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNS--GITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCAS--PGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK69-1", "uniprot_id": "Q9VK69_DROME", "id": "Q9VK69-1", "name": "T-complex protein 1 subunit delta", "aln": "----MAPKAAAVNIKPTAK---AFKDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQMSTPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLGGTVEDTELVDGLVFTCRSAGSN-APKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLKEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEFVCKTLHCRPIASLDHFTAENLSSADLVEEVAS-GTNKFVKITGIQN--MGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKGAITDIFAENVVQPLLVSISSITLATETIRSILKIDDIVNTFS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39078-1", "uniprot_id": "TCPD_YEAST", "id": "P39078-1", "name": "T-complex protein 1 subunit delta", "aln": "----MSAKVPSNAT---------FKNKEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGALLGAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSLSDREQLVRAASTSLSSKIVSQYSSFLAPLAVDSVLKISD-ENSKNVDLNDIRLVKKVGGTIDDTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVNDYRQMDKILKEERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLGCKPIADIELFTEDRLGSADLVEEIDSDGS-KIVRVTGIRNNNARPTVSVVIRGANNMIIDETERSLHDALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPTTLAENAGLNSIKVVTELRSKHENGELNDGISVRRSGTTNTYEEHILQPVLVSTSAITLASECVKSILRIDDIAFSR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: . ::::.** ::* :** **::*:*********:******: ..*:: *:*** ****** :***.*:****:* *** *********:::*:** :. :**:**:*** *::*** . ::.::** :*. :.*.*** *:.:*:***.**:*** **:*:*::*::*:*: * . ..***.:*:::..:***::* *:::*:*:* * . .* ********** :*.**.* :::::*.** **::*:***:*:**: *:***: *****:********:.*** ***.*:: **:**:***:***:.* : :*:* :: ** : *.**:*.**: *: *:.::** . **::: **:*:::::*: **:******:***** *. *.********:: :*: ::::.*:::: : **.*:****:*********.* .*****.:* :** . **.**:.. :: * ::**:*** *::***:* ::***:***:. : ", "identical_positions": 260, "similar_positions": 182, "identity": "47.79%" }, { "cls_id": "homologset.agr.SGD:S000002304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6T1-1", "uniprot_id": "G3V6T1_RAT", "id": "G3V6T1-1", "name": "Coatomer subunit alpha", "aln": "--LLSSADTRHAYVTKENSLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPG--AVESDVRGITG-VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYV-KDRFLRQLDFNS---SKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDR-MHSLLIKNLKNEITKKIQVP-NCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKE--TIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKG----------GALAADIDIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDTLG-KGQEEGGGWDVEEDLELPPELDVPSGVAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVVQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLSTVGKFEDAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIE6-1", "uniprot_id": "COPA_MOUSE", "id": "Q8CIE6-1", "name": "Coatomer subunit alpha", "aln": "--MLTKFETKSARVKG---LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPG--AVESDVRGITG-VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYV-KDRFLRQLDFNS---SKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDR-MHSLLIKNLKNEITKKIQVP-NCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLSAATHGLDEEAESLKETFDPEKE--TIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKG----------GALAADIDIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDVLG-KGQEEGGGWDVEEDLELPPELDVPSGVSGSAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53621-1", "uniprot_id": "COPA_HUMAN", "id": "P53621-1", "name": "Coatomer subunit alpha", "aln": "--MLTKFETKSARVKG---LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPG--AVESDVRGITG-VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYV-KDRFLRQLDFNS---SKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDR-MHSLLIKNLKNEITKKVQVP-NCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKE--TIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKG----------GALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALG-KGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0B8-1", "uniprot_id": "Q9W0B8_DROME", "id": "Q9W0B8-1", "name": "Coatomer subunit alpha", "aln": "--MLTNFESKSARVKG---LSFHPKRPWILVSLHSGVIQLWDYRMHTLLEKFDEHDGPVRGVAFHQQMPLFVSGGDDYKIKVWNYKQRRCIFTLLAHLDYVRTVAFHHEYPWILSASDDQTIRIWNWQSRNCICVLTGHNHYVMCAQFHPTEDQIVSASLDQTVRVWDISGLRKKNVAPGPGGLDDHLKGHPGATDLFGQADAVVKHVLEGHDRGVNWASFHPTLPLIVSGADDRLVKLWRMNEYKAWEVDTCRGHYNNVSSVLFHPRQDLILSNGEDRSIRVWDMTKRQCLFTFRRDNERFWILTAHPTLNLFAAGHDGGMVVFKLERERPAYAVHGNILYYV-KERFLRKLDFTT---TKDTVVMQLRPG-KSPVYSMSYNPALNAVLICTRTNNLENSTYDLCQIPKDTESQS--ESDSKRSSGITAIWVARNRFAVLDR-NQQLVIKNFKNEVTKKLPT--FCEEIFYAGTGMLLIRDPEFVTLYEVQRLVSVGSIKLAKCRYVVWSPDMSLVALLCKHSVTICDRRLQYLCTVQENCRVKSGAWDESGVFIYTTSNHIKYAITNGDHGIIRTLDLPIYLTRVKGNQVFCLDRECRTRVLHIDPTEYKFKLALIQRKYDEVLHMVRNARLVGQSIIAYLQQKGYPEVALHFVKDEKTRFGLALECGNIEIALEAAKALDDKDCWDRLGQSALLQGNHQVVEMCYQRTKNFDKLSFLYLITGNLEKLKKMNKIAEIRKDVSAQYQGALLLGDVKERVNILKNCGQLSLAYLTAATHGFDELTESLGESITSQGN--SLPEVNPNAQLLQPPVPIQQLETNWPLLSVSKGFFEGAMVTRAGSSATARQALNINADAALLDEHNGGGDGWGADADLGLDEDGDDEMHDALSNDGDGGAGGEEGAGWDVGDDDLVVPEELASKIKASALDSNYYAAPNKGLSPAQQWANNSPLVLDHVKAGSFETAFRLLHDQLGVVNFQPFKTLFLQNYACSRTSYTANPNLQSLSGYPLRNYSETNIKLQRPAVGIKLNDLVARLQAGYQLTTSGKFSEAVEKFHSILISIPLLVVDTKLDAAEAQQLLRICAEYIVGLKMETVRKGMPKSTLEEQKRLCEMAAYFTHCKLQPVHQILTLRTALNMFFKLKNYKTAASFARRLLELAPRPDVAQQVRKILQACEVNPVDEHQLQYEEFNPFTICGISWKPLYRGKPEVTCPFCSSSFDPQFKGNLCTVCEVSQIGKDSIGLRISNLQFR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53622-1", "uniprot_id": "COPA_YEAST", "id": "P53622-1", "name": "Coatomer subunit alpha", "aln": "MKMLTKFESKSTRAKG---IAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGS-LGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQNQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVN-----EANGKFALVILPKQP-VGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRNIKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVALMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIKTLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNLVGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLIQEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNTFYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDASNFVQRPVISKPLEK-WPLKEAELSYFEKAVLG-------------------QIDDLTIDDETPAVNTTQEQEEP---LGEENFNDEDIG----EDEGAWDLGDE-----DLDVGEELPEEVEQGEITSPAQ-EVETAIWIKNSKLPAVLVAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYDDTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAEDEKLAHKILETAREYILGLSIELERRSLKEG---NTVRMLELAAYFTKAKLSPIHRTNALQVAMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAKFDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:. ::: : .. ::***.***:*.:*....******** **:.:*::*:*****: ** *:***.****.****. . .:*::** .****:**. **:* ***:*********:****.*. :. ******:********::* :******:*:*:********:: :** ..:..: . . * *.***.:**** ******:****:******:*** **:***. *********** ***...:***:*:**:* .**:::****: ** : *:*:::***:::*** :***.*.**.*::****:****. :* * *.:* :: ::.::* . : . :: .. .:****: ::**: *..: * :**:. .. .:.:* * :*.****.* :: ..: ::.::*::*::: . *. **.* :*: .. : *::**: .:..: : : :** ** * . ***:.**::.:. ::*: : .::*. *:**.****:**:**:* ***:*:: .**:***:**: .:*:*:*:*: *:**:** . .:* *****::** **::::: ***::::::.****.**:***:.****:**:**:* : **.**** **:::**: ** *:*.. *::* : ** *** .:.** ** :.*********:**:::** ** :**: *:*... .:: ....** *: : *. .*** * ::* : :.:: * : : ::*: ::::* *. *:. *** .. .:** :: :* . . : . :: :* : :.:: * *: ..**: :: : . :.. ..* : : * :** * : **:*::*.: * .*:**::: * * * : * ** : * . * :.:: : . *: : ::: *: . .* . *:* *:. : :.**:** : *:::: . ***:** :* *: : : : *: *:*****:.:*.*:* .*:.*:. .** **: *: ** .:*:: . *:*.*** . .: . * :::: . * **. :::*:*...* . *: .: : *.:: : :::** **** ", "identical_positions": 443, "similar_positions": 422, "identity": "35.41%" }, { "cls_id": "homologset.agr.SGD:S000002305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWX4-1", "uniprot_id": "D3ZWX4_RAT", "id": "D3ZWX4-1", "name": "", "aln": "MLEPTHPWGGAFGSRACARVACHGAGRGERGTQGLGFPALQPSSRTQHRRGAERPGLMYRALYAFRSAEPNAMAFAAGETFLVLERSS-THWWLAARARSGETGYVPPAYLHRLQGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQ------RGVLQKLIHHRKETLSRRGTSAASASVMTPSTSDHHLDTAVSRQPNGVCRTGFERQHSLPSSEHLG-----------------------TDGALYQVP-------------PQPRRAAPATPPPPVKRRDREALVISGSGGRTAVPSGGSSVSSGSSVSSTSMDTLYTGSSPSE-------LGPSCSPTPPPVPRRSAHTTVSQ---------------------------------AQPSPSKAPSPEPP-AEEVAAETNSAPDDLEALDALSPETTEEK------------PATETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQASVPASSPVMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPLDATEQLPDLCMNLLLALNLHLTAPDQNVIMAALSKHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSAATASIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEETSPQCQMDRMIVQEMYKEFPDLGEVPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESJ4-1", "uniprot_id": "SPN90_MOUSE", "id": "Q9ESJ4-1", "name": "NCK-interacting protein with SH3 domain", "aln": "---------------------------------------------------------MYRALYAFRSAEPNAMAFAAGETFLVLERSS-THWWLAARARSGETGYVPPAYLHRLQGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQ------RGVLQKLIHHRKETLSRRGTSASSATVMTPSTSDHHLDAAVSRQPNGVCRTGFERQHSLPSSEHLG-----------------------TDGALYQVP-------------PQPRRAAPTTPPPPVKRRDREALVISGSGGRTAIPSGGSSVSSGSSASSTSMDTLYTGSSPSE-------LGPSCSPTPPPVPRRGAHTTVSQ---------------------------------PQPSPSKAPSPEPP-TEEVAAETNSTPDDLEAQDALSPETTEEK------------AAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQATVPASSPIMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPMDTTEQLPDLCMNLLLALNLHLTAPEQNVIMAALSRHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSSATAAIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEEASPQCQMDRMIVQEMYKEFPDLGEVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZQ3-1", "uniprot_id": "SPN90_HUMAN", "id": "Q9NZQ3-1", "name": "NCK-interacting protein with SH3 domain", "aln": "---------------------------------------------------------MYRALYAFRSAEPNALAFAAGETFLVLERSS-AHWWLAARARSGETGYVPPAYLRRLQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQ------RGVLQKLIHHRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLG-----------------------ADGGLYQIPLP------SSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSE-------PGSSCSPTPPPVPRRGTHTTVSQ---------------------------------VQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEK------------AAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQMEHRAS-----LRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3K6-1", "uniprot_id": "Q9W3K6_DROME", "id": "Q9W3K6-1", "name": "SH3 domain-containing protein", "aln": "---------------------------------------------------------MLKALYDFQAVYPKTISFDEGEYFILYQTSARQRNWWQVVSMKGNIGFVPSNYVMKIKVEHDFLISFLNSSIESLEKCTDHEINGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEGATGGGQLKVESSDVYQIVDALRRNTNLSFDLSCEALRVVLTSLEQLYNGAINPYLEAVAVHVTGKVATPKELLG-ITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFLEELVEILINADESISCYEMSCDQYQMFINLVQYYQMETRWS-----IKRLLLKTFTAACHLDYIIVDILLTSVLPLEIVEDMKTHFSNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIVEG----NNPEVLVDMVIALILAFNQQFSEHTYNVIIEGMQNLPSAKVFTEKLLLLLNREDDPTRLLKHPNEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDLDAGSTTRPCYLELCRRILRNTNYQEHQHRKHDLMKIFTRIFCEETECSAS--DQQLVREIANEFPQLFKA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12342-1", "uniprot_id": "LDB17_YEAST", "id": "Q12342-1", "name": "Protein LDB17", "aln": "--------------------------------------------------------------MILDPLSPNIENHTQDEIIEFWEKTE---SIANIPKENLDESHVNSSLVAYLKFATDSYKVFINTDRDLYR------------------------MSLILLESSLFEFKKEFCLSKLQSLLNIDLLEMNMKFIIVYILLCEAKKNVYSLEIMLKFQG--------------------------------------------------------FTVFYNTLYTQFAYLSKYGKERTVASKHQYNSNNSSTGTSLDSLDR-------------------------------------------------------------------------------------------------------------------------------SLTDIDLGIIDEMKQISTVLMDLLFQIMKYCK-CVIANLQIVDDFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQ------YMMFAKEYDIENKVYKYLINGSVSRCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPMNFFYTNDLRVLIDVLIRELQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLLNYLSTLDNICVDSPALHEHQVTVALSRKCLQQIPWLETPSTPSDG---------GSSVSSNNTSRNSSIVALGTPDNQNILARKGHLYSNRE------------------------------------------LDVSAESLTKRKAKAPPPPPPPPPSRKCGTPK---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: . .* : . : : . : ..* . : :: : :: : . .: . . . * . . . . .: . * . . . : . ...* :. . :: : :: : .* .:: . :: :: : : . .. . : : : : : * ::: : : : * *: : *. : . * *: : : :*:: : . : : . *: ::*: ::.. : : *: : .: * * . : . :: *. : . .. . . * : .: . ::::.* * ** :*: .. ::. .. : . ", "identical_positions": 26, "similar_positions": 139, "identity": "2.98%" }, { "cls_id": "homologset.agr.SGD:S000002306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAD5-1", "uniprot_id": "A0A8I6AAD5_RAT", "id": "A0A8I6AAD5-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAK----------------------ASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESDKWQQALKSVVLYVILAPFDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSSETPATDVFS-STEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8W5-1", "uniprot_id": "PSD12_MOUSE", "id": "Q9D8W5-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTENLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESDKWQQALKSVVLYVILAPFDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSSETPATDVFS-STEEGEKRWKDLKSRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00232-1", "uniprot_id": "PSD12_HUMAN", "id": "O00232-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFG-STEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Z4-1", "uniprot_id": "Q9V3Z4_DROME", "id": "Q9V3Z4-1", "name": "", "aln": "MDTYLFD--GGRITKMEVDYEPACNEKIPLAKELAKKNPDAFHEAIEMMLQLEKQTRLGADMVSCSRVLVAICQICFDASNWNALNEYVSLLVRRRSQLKQAVVKMIQECVTYVDKTP--DKETKLKLIDTLRSVTEGKIYVEIERARLTKILADIKEADGDVAGAATVMEELQVETYGSMDKREKVELILEQMRLCLLKEDYVSTQIIAKKISIKFFDDPAQHDLKLKFYYLMIQLNRDT-SFLNTSRHYQAIAEPPRKKTGLTPVDSAASTDEQKKKDDDKKKKEEDDKDKKPEVATEAEVEIELTEEQKKELTEKLVCAVLYCVLAPFDNEQSDMMAHLSKNKKLEEVPAYKEILRLFMSKELINFDTFNADFGLVLAEN-------EMFKDSTKHGKKCITELKDRLIEHNIRIIAMYYSRLHLARMSELLNLPTSRCEEYLSKLANTDTIRVKIDRPAGIIYFTQKKSASDILNNWATDVNQLMSLVNKTCHLINKEECVYSVMCAVED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12250-1", "uniprot_id": "RPN5_YEAST", "id": "Q12250-1", "name": "26S proteasome regulatory subunit RPN5", "aln": "MSR-------DAPIKADKDYSQILKEEFPKIDSLAQND---CNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYESLKLEYYNLLVKISLHKREYLEVAQYLQEIYQTD------------------------------------------------AIKSDEAKWKPVLSHIVYFLVLSPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDD------LAFG--GEANKHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : **. .:.:* .**: .:*:.* ..:*. : .: . .:*: *** : ** :::.*** :: *:*: *:.. * :: :*:*:* ***.**:**:****:** *. **: :*.: ** :: **********: *::::*****.*.: ** : ::::** * *.: ..***::* *::::. . .:*. .:: : * :. : :. : * * : :*:*:.* *.*:: ::. :::*::: :.:::** : **:.: . : * :. * : .:: :*:.*::***:*::: **:*: : *: :**:*. .. * ::*.*. * .*::* * :: * : *...::**:*: .::.*:. ::. *** *** ::.: ", "identical_positions": 121, "similar_positions": 172, "identity": "23.54%" }, { "cls_id": "homologset.agr.SGD:S000002307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Z9-1", "uniprot_id": "A0A0G2K0Z9_RAT", "id": "A0A0G2K0Z9-1", "name": "", "aln": "------------------MGKAKRTGARRQVHKAPAGAFG--------GPGKTNPNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSNISPEEKMMKR----FALEQQRYHEKKNIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDTEDRGALSAELTASHFGGG--VHKNSSQKEGEDGDKPKTRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILLSRKSKKSENKEKKEKPQPDAYDMMVRELGFEMKAQPSNRMKTEEELAKEEQEKLRKLEAERLRRMLG---KDEHENKKKPKHTSADDLNDGFILDKDDRRLLSYKDGKMNIED-AQEEQSKGADGQENDQKEEEDESEEEGEDGESCEDPDESDGPDSHSDLESSAETEEEDETPKKEQRQTPGGKSPKEAQKAQKAAAAELPYVFAAPESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGNKAKLEKLFGFLLQYIGDLATDSTPD-----LKTIDKLVVHLYNLCQMFPESASDAIRFVLRDAMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQMLTKCPVTSLRDVVKGLFVCCLFLEYVSLSRRFVPELLNFLLGILYIATPNKKSQGSTLVHPFRALGKNSELLVVSDKADVTTWQRGSLPLHWANRQSTLTATEANHTRLSCVASCLSLLKHCVLMYSALPSFHAIVTPHQALLAEHLAR-SLPQELQELSRSILSEVESQKQHCPPLICEKSKPVPLKQFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEVD----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3N1-1", "uniprot_id": "NOP14_MOUSE", "id": "Q8R3N1-1", "name": "Nucleolar protein 14", "aln": "------------------MGKAKRTGARRQVHKAPAGASG--------GPAKTNPNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNISPEEKMMKR----FALEQQRYHEKKNIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDTEDRGALSAELTASHFGGG--VHKNSSQKEGEDGDKPKTRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMSRKPKKSEDKEKKEKPQPDEYDMMVRELGFEMKAQPSNRMKTEEELAKEEQERLKKLEAERLRRMLG---KDEHENKKKPKHTSADDLNDGFILDKDDRRLLSYKDGKMNIED-VQEEQSKEADGQENDQKEGEDDSEEEDE---SHEDSEESEDPDSHSDLESNIESEEENETPKKEQRQTPGGKLPKDDQKAQKAVAAELPYVFAAPESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGNKAKLEKLFGFLLQYIGDLATDSTPD-----LKTIDKLVVHLYSLCQMFPESASDSIRFVLRDAMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALLCMSQMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGILYIATPNTKSQGSTLVHPFRALGKNSELLVVSDKADVTTWQRGSLPLHWANRLSTLTATEANHTRLSCVASCLSLMKHCVLMYQALPSFHAIFRPHQALLSKHLADCSLPQELQELAQSILSAMEGQKQHCRPLVCEKSKPVPLKQFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78316-1", "uniprot_id": "NOP14_HUMAN", "id": "P78316-1", "name": "Nucleolar protein 14", "aln": "------------------MAKAKKVGARRKASGAPAGARG--------GPAKANSNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMSPEEKMMKR----FALEQQRHHEKKSIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDAEDRGTLSAELTAAHFGGGGGLLHKKTQQEGEEREKPKSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEAELAKEEQEHLRKLEAERLRRMLG---KDEDENVKKPKHMSADDLNDGFVLDKDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEGDSSGG---------EDTEESDSPDSHLDLESNVESEEENEKPAKEQRQTPGKGLISGKERAGKATRDELPYTFAAPESYEELRSLLLGRSMEEQLLVVERIQKCNHPSLAEGNKAKLEKLFGFLLEYVGDLATDDPPD-----LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMHEMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQLLTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILYIATPNKASQGSTLVHPFRALGKNSELLVVSAREDVATWQQSSLSLRWASRLRAPTSTEANHIRLSCLAVGLALLKRCVLMYGSLPSFHAIMGPLQALLTDHLADCSHPQELQELCQSTLTEMESQKQLCRPLTCEKSKPVPLKLFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEJ2-1", "uniprot_id": "NOP14_DROME", "id": "Q9VEJ2-1", "name": "Nucleolar protein 14 homolog", "aln": "-----------------MVAKGKKASADAVYAKKTTRSANPFDN--STAQSSKRGNPFDVHVNKEKFK---ILGRICKHDRGMPGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIGKHLSGDQLTESVMNARYLAEKMSQVRSNQKAEKFNLNDDEL-LTHRGQTLEEIEQYRDERSDDEELDDEALDADFTAAAHFGGE--------------GDSAQDRQAAIDEMIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVAKVTKD----EQDAKPPPDAYDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLENERLRRMRADGEEDEEASVAKPKHRSADDLDDGYFLAGEDDEGDDTLAYDLDGNLGTHLNGKKEAVLKGDENEDDDDKEGEEE------EEEDSDEESDSEVDNLSDLK-ESESESEPEEAPKASKKKAKKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHATAQKAIIIERIIKCNHPKLEGVNRENVVKLYSFLLQYLKDLFEDASEQDIREHFQLLSKLMPYLYELTQLNPERMSNTLLEVIKEKYEEFR-----KNHKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQEISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVHMSIPKRDVEQLEITPPFERDGPLSKLLALPANTESTKLEPQQLQP-----TDLVTQTITPDFKVRALDTSLLLIKEALQLVEEHVGACYLAQPFLALLSRLPLESYPEHVHQHHKDATELAEKLAAQKMKPLAPAEKKPKALRLLEPRFEAVYDDKRR-PKMSKAKEERAKLLHKIKREKKGAIREIRRDTSFVQMLRLKQTLQSDKERHEKVKRIYQEASVQQGELNELSRAKKKKKF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99207-1", "uniprot_id": "NOP14_YEAST", "id": "Q99207-1", "name": "Nucleolar complex protein 14", "aln": "MAGSQLKNLKAALKARGLTGQTNVKSKNKKNSKRQAKEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGKPGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLTEEEKMLER---FTRERQSQSKRNANLFNLEDDEDDGDMFGDGLTHLGQSLSLEDELANDEEDFLASKRFNEDDAELQ-------------QPQRKKTKAEVMKEVIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPKKNPMEPKTDLD-KEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRLDRMNG------MIELEEGEERGVEDLDDGFWENEEDYE-----------------------------------------------DDNDGIADSDDDIKFEDQGRDEGFSQILKKKN------------------------ISISCPRTHDALLDQVKKLDLDDHPKIVKNIIKAYQPKLAEGNKEKLGKFTAVLLRHIIFLSNQNYLKN----VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGD-LVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVEKENQ--EKPLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMDTEAHPVDQCVSV-LLNVMESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPRNILNKVEKLTKFT--EHIPLALQNHKPVSIPTHAPKYEENFNPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKYERERKLRGGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . : . . . ***:::. ::* : : * **:*: . .:* ::: . :.* . . *:*:*: . *.::: * : :.: . :**::** *: * .: : . .. : :: : . : : : :.*:*.:.* *.* : : ::** ::: : : . : . . . ** ::*: :: :. ::: . * : : .:** :** ** . . : :. ..:**:**: :* . :: : .*.. . .. . * .: :: : *.:.: : : :: :::.* *. :*.* *: :: *: ..**.:: * : . . :.: * : : .* . : :: .*:. : .. * *:::.: . *:.*** * *:**.:: :.:.* : . : : : * .: :. :: *:* :* :. *: *: : : *. * * :. : :. . : : . : : * : . : * **: . :. : ** : ** .: *: : :: .: ..* :: : *:* * :::***:* .* ::.: : . : : *: :: : .:: ", "identical_positions": 97, "similar_positions": 257, "identity": "10.61%" }, { "cls_id": "homologset.agr.SGD:S000002308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABD5-1", "uniprot_id": "D4ABD5_RAT", "id": "D4ABD5-1", "name": "Autophagy-related protein 9", "aln": "----------------------------------------------------------MVRRMGWGGSRRQRGRWGDLGPSSVPLLPMALPLPASP-CRGLGGGRISVFSLSPAPRTRSCSSSLFPPTSGSPSLVIQEAGASQPPFN-------------------------------------------ALPTPATPPTQALPTMTHTSASPSWGSHSTPPLASVTPPPSCRC------PQDHPGLRIGPLIPEQDYERLEDCDPEGSQDSS--SPVHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRPGPLHSKVTLSDAILPSAQCAEKIHGSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQ------PRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLATRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPATAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDED------VLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGAAGARTSSYWQMSQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALQIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAED------------GKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVSPRP------------------------PQRDLSPTAP--CPAAA-TASLLASISRMAQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQ-EVWGEASASSPSRP--WSSPSQPGSPDEEKPSWSSDGSSPASSPR--------------QQWG-------TQRAQNLFP---------KDFQETTDAQKEPLPGSLH----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6EBV9-1", "uniprot_id": "ATG9B_MOUSE", "id": "Q6EBV9-1", "name": "Autophagy-related protein 9B", "aln": "----------------------------------------------------------MVRRTGWGGSRRQRGRWGDLGPSSVPLLPMALPLPASP-CRGTGGRRISVFSLSPAPRTRSCSSSVFPPASGSPCLVIQEAGASQTPHN-------------------------------------------VLPTPTTPSTQAHPTMIHTSASPSWGSHSTPPLASATPPPSCPR------PQDHPGLRMGPLIPEQDYERLEDCDPEGSQD----SPIHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRRGPLHSKVTLSDAILPSAQCAEKIHDSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQ------PRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGSSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLANRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPAAAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDED------VLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGATGARASSYWQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAED------------GKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVNPRP------------------------PQRDLSPTAP--CPAAA-TASLLASISRMVQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQ-ELWGEASASSPSRP--WSSPSQPGSPDEEKPSWSSDGSSPASSPR--------------QQWG-------TQRAQNLFP---------KGFQENTDTQKEPLTGPLH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q674R7-1", "uniprot_id": "ATG9B_HUMAN", "id": "Q674R7-1", "name": "Autophagy-related protein 9B", "aln": "----------------------------------------------------------MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHS-------------------------------------------ALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQC------PQDSPGLRVGPLIPEQDYERLEDCDPEGSQD----SPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQ------PRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDED------VLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGP-GGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAED------------GKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLL------------------------PPRDLSPTAP--CPAAA-TASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRP--CSSPSQPPSPDEEKPSWSSDGSSPASSPR--------------QQWG-------TQKARNLFP---------GGFQVTTDTQKEPDRASCTD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FE2-1", "uniprot_id": "ATG9A_MOUSE", "id": "Q68FE2-1", "name": "Autophagy-related protein 9A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYSDSPPG----------EEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLS--PLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIP-DQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGR-VPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWU3-1", "uniprot_id": "ATG9A_RAT", "id": "Q5FWU3-1", "name": "Autophagy-related protein 9A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYSDSPPG----------EEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLS--PLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIP-DQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLSRDLQGSRHRADVASALRSFSPLQPGQAPQGR-VPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRAPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3C6-1", "uniprot_id": "ATG9A_HUMAN", "id": "Q7Z3C6-1", "name": "Autophagy-related protein 9A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQFDTEYQRLEASYSDSPPG----------EEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEAVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLS--PLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHVLTTVTLLGVTVTVCRSFIP-DQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSAGQTEASVYQQAED------------GKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAASLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLPRDLQGSRHRAEVASALRSFSPLQPGQAPTGR-AHSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQAQAEPERHVWHRRESDESGESAPDEGGEGARAPQSIPRSASYPCAAPRPGAPETTALHGGFQRRYGGITDPGTVPRVPSHFSRLPLGGWAEDGQSASRHPEPVPEEGSEDELPPQVHKV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KF86-1", "uniprot_id": "A0A0B4KF86_DROME", "id": "A0A0B4KF86-1", "name": "Autophagy-related protein 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPHINYRSLAEEAASPFLEHHPSTGQG---PSKTQDA------KANAAAAHLDPLGEHGLEQPLDEHDTEHEGE-----DTPRNSGVMIHMVPETGRARWNHIEDLDSFFSRMYQYQQKHGFTVIVVDEMLQVLEFGFVVWLLAFVMHCVRFDVLFGDTPP----GGLNPNKTTLSDVMYPTGECLANFT--WVTYLVVFIAAIYLGIRLLKMVYHITQYADIKRFYNSALHIEDSDLDNFTWHEVQQRIRRVQAEQHMCID------KESLTELDIYHRVLRFKNYLVALMNKQLLPVRFHIPLYGEVVSLSRGMLFNIDFILFRGPGSPFQNNWQLRDEFAVRSNQTELAQRLSKLILGVALLNLVLAPVIFVWQLIYFSFSYANILRKEPGALGLRTWSNYGRLYLRHFNELDHELDARLNRAYDYADRYLNSFSS--PLAAVIAKNLLFISGGLLLLILALGIYEEH------VFQVEHLLAILAGLGAIGVVCRTLIP-DENLVWCPEQLMTAILAHVHYLPSEWRQQAHTTKVRQEFSNFFQFKAGYLLSEIFSPFVTPFVLIFVFRPKAIELVRFFRTFTVSVRGVGNVCSFAQMDVRKHGNPDWQLTSELEEMTRATAQQPQQEPQQQSLAGGKTEMSLLRFTLNNPEWQMPKEAKQFLRGVREHAVGELVQAKTSMVQENPLTNSLISFGTMGADYCSIANSVLTAQVTP--------------------QQLEISQSLRPGLGPVSGGFPVAASDFRQMLQQNLSASVGPLDSMRRLRLSRAEGRLEGPTDTLLYGLCGVDPRVGSTPLNVGVADMCLSALYLHELNQQKRQARQSRIDEAEDERPGTS---------------HWP--PRPPAAPSADTGFG-------SRHTVITSKAAESTPLLGSIRSXQRPEWI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12142-1", "uniprot_id": "ATG9_YEAST", "id": "Q12142-1", "name": "Autophagy-related protein 9", "aln": "MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLDGDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDDDTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLP--------------TSHRVSDIIIDKCYSNSITG---FTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLF-RTNVLTKTLEWNINLCVMG---FVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPK--EKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTIT-QEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIAVNG---------------------------------------SHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQ------------------------------------LPAKKGYPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDNNNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPN-----------------------HDVIDHNKMLN---------SNYNGNGILNKGGVLGLVKEYYKKSDVGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * * * ::::** *: :*. :** ::: .:::: : *:* . ::: ** :. * . :.* : . .: : : :::: .: ::: ** *.* . * .* :* :: : . : . . : *: :*::* ** :** *. :* :* . ::: : *.:: :: * : . : . . .: . *: *.*.:. : :: : : : : .**::* * :: .. :*.:*** * : *: . * :: :: : *:.*.:. : * ::: . : . :: :: **. *.*. *. :: .: : : **:*.. ::.:: : : :* *: * ::**:.* * : . * .:: **: : * *:* *.:* ::::. . : .: . .: . . : . : . * . : . . : . :: . . . . . . . : . : . ", "identical_positions": 76, "similar_positions": 200, "identity": "6.74%" }, { "cls_id": "homologset.agr.SGD:S000002309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZS9-1", "uniprot_id": "Q4FZS9_RAT", "id": "Q4FZS9-1", "name": "", "aln": "MSEGNAAG------EPSNPGGP--------RPLLSGGRGLVGRRPAPPLTPGRLPSIRSRD-----------LTLGGVKKKTFTPNIISRKIKEEPKEEVTMKKEKRERDR---DRQREGHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVDMSDMGPSHIINIKKEKRETDEETKQILRMLEKDDFIDD------PGLKNDTRNMPVQLPLAHSGWLFKEESEEPDVKPFSAGPKEEDMEVDVP--AVKVKEEPRDEEEEAKVKAPPRAARKTPGLPKDVSVAELLRELSLTKEEELLFLQLPDTLPGQPPTQDIKPVKTEVQGEDGQMVVIKQEKDRETRLAENACTLADLTEGQVGKLLIRKSGKVQLLLGKVTLDVTMGTTCSFLQELVSVGLGDSRTGEMTVLGHVKHKLVCSPDFESLLDHKHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WD1-1", "uniprot_id": "RPC4_MOUSE", "id": "Q91WD1-1", "name": "DNA-directed RNA polymerase III subunit RPC4", "aln": "MSEGNAAG------EPSNPGGP--------RPLLSGGRGLIGRRPAPPLTPGRLPSIRSRD-----------LTLGGVKKKTFTPNIISRKIKEEPKEEVTMKKEKRERDR---DRQREGHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVDMSDMGPSHIINIKKEKRETDEETKQILRMLEKDDFIDD------PGLKNDTRNMPVQLPLAHSGWLFKEESEEPEAKPFSAGPKEEDMEVDVP--AVKVKEEPRDEEEEAKVKAPPRAARKTPGLPKDVSVAELLRELSLMKDEELLFLQLPDTLPGQPPTQDIKPVKTEVQGEDGQMVVIKQEKDREARLAENACTLADLTEGQVGKLLIRKSGKVQLLLGKVTLDVTMGTTCSFLQELVSVGLGDSRTGEMTVLGHVKHKLVCSPDFESLLDHKHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05423-1", "uniprot_id": "RPC4_HUMAN", "id": "P05423-1", "name": "DNA-directed RNA polymerase III subunit RPC4", "aln": "MSEGNAAG------EPSTPGGP--------RPLLTGARGLIGRRPAPPLTPGRLPSIRSRD-----------LTLGGVKKKTFTPNIISRKIKEEPKEEVTVKKEKRERDR---DRQREGHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVDVSDMGPSHIINIKKEKRETDEETKQILRMLEKDDFLDD------PGLRNDTRNMPVQLPLAHSGWLFKEENDEPDVKPWLAGPKEEDMEVDIP--AVKVKEEPRDEEEEAKMKAPPKAARKTPGLPKDVSVAELLRELSLTKEEELLFLQLPDTLPGQPPTQDIKPIKTEVQGEDGQVVLIKQEKDREAKLAENACTLADLTEGQVGKLLIRKSGRVQLLLGKVTLDVTMGTACSFLQELVSVGLGDSRTGEMTVLGHVKHKLVCSPDFESLLDHKHR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25441-1", "uniprot_id": "RPC4_YEAST", "id": "P25441-1", "name": "DNA-directed RNA polymerase III subunit RPC4", "aln": "MSSNKGNGRLPSLKDSSSNGGGSAKPSLKFKPKAVARKSKEEREAAASKVKLEEESKRGNDKKHFNNKNKRVTGAGGQQRRMAKYLNNTHVISSGPLAAGNFVSEKGDLRRGFIKSEGSGSSLVQKGLETIDNGAESSENEAEDDDNEGVASKSKKKFNMGKEFEARNLIEDEDDGESEKSSDVDMDDEEWRSKRIEQLFPVRPVRVRHEDVETVKREIQEALSEKPTREPTPSVKTEPVGTGLQSYLEERERQVNEKLADLGLEKEFQSVDGKEAAAELELLNADHQHILRKLKKMNNKPERFMVF--QLPTRLPAFERPAVKEEKEDMETQASDPSKKKKNIKKKDTKDALSTRELAGKVGSIRVHKSGKLSVKIGNVVMDIGKGAETTFLQDVIALSIADDAS-SAELLGRVDGKIVVTPQI---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..:. * :.*. ** :* . :. *..*.. . . * *..* ** ::: . :: *.. * .. .** : * . : .* . : *.*:. : .:. ** .::* .*: . :** .. . *..: .*. *. ::.::: .. * .*: *: . :.*: . . . : * .:: : :*:*: * * :.:: : :.. .:**:*. ::: *: : ** : *: : .:* * :. : * .::*.. : : . : *:**.: ::***::.: :*:*.:*: *: :***:::::.:.*. : . :**:*. *:* :*:: ", "identical_positions": 71, "similar_positions": 153, "identity": "16.36%" }, { "cls_id": "homologset.agr.SGD:S000002312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX4-1", "uniprot_id": "SAS10_RAT", "id": "Q6AXX4-1", "name": "Something about silencing protein 10", "aln": "MVKRSRRRGAAQWATVRAKAGRTATDENEDDLGSPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDD--DEEEEVLPLNIDDENDEDGESS--EEEEDGE------------DDDGGSSVQSEAEASVDPSLSWGQRKRLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQVIQRRLTQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEP-LIQLVEKGVIPPGKGSQYLKTKYNLYLNYCANISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTAKEGA----------GKKDLNPKAKLTKTKPKSAKQTDVN----ADLTEEPEFDE--------AALEFYKEMEDRPELKRKKEENSAEEQALEE-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRREEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI13-1", "uniprot_id": "SAS10_MOUSE", "id": "Q9JI13-1", "name": "Something about silencing protein 10", "aln": "MVKKSRRRGAAQWAAVRAQAGLTATDENEDDLGLPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDG--DEEEEVLPLDIDDGDDEDGESS--EEEEVGE------------DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLKKESPELLELIEDLQAKLTEVKDELEP-LLQLVEKGVIPTGRGSEYLKTKYNLYLNYCANISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTAKDGA----------VKKEMTPKAKLTKTKPKSVKQAAA-----VALTDEPDFDG--------AALKYYKEMEDRQELKRKKEENSAEEQALEE-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRKAKIRRRGQVREVRREEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQZ2-1", "uniprot_id": "SAS10_HUMAN", "id": "Q9NQZ2-1", "name": "Something about silencing protein 10", "aln": "MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA------------DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEP-LLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTLKDDA----------VKKELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEK-------AKLKYYKEIEDRQKLKRKKEENSTEEQALED-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7W5-1", "uniprot_id": "SAS10_DROME", "id": "Q9I7W5-1", "name": "Something about silencing protein 10", "aln": "------------------------MDSDGDDYVMSGS--DQEYDDEEREILEDLRKQRKKPH--------------DPVQEVLGFSDDDDDDDDDDEE-EQQDVAEL------------MRDSDIEGAEDDDRDLPNTMDWGSKRSTYYNTDFVDQDYSSYNAQEEEQ-ARAEEEEAKKIQLRLAKRMSEADFQLDNVEAAPAGSSDDNELSHITKVTSDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLLKP-VLNYVRKHDVPMVPALQYAGLCHTVLTTYCSNVAFYLLLKAR----------------------------------------------------------------------------------------------RIDVKAHPVIRRLVQLKDLIE----ELKPRYEEYIRPQLEALLERIED----------GDAFTVLDVAQRKAKLQILNKYNDG----QQASVSSDDDD---------------NDDDDDAESKEKDLQEEAGEEEEE-------------------EDARRGITYQMAKNKGLTPHRKKELRNPRVKHRGKYRKALIRRKGAVRTVRKELQR--YGGELSGIKAGVTKSVKFRT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12136-1", "uniprot_id": "SAS10_YEAST", "id": "Q12136-1", "name": "Something about silencing protein 10", "aln": "--------------MVRKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFGDSNKDDDHSLLED-----EDEEEVLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLETDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELNMNDYLDEEE-EEEWVKSAKEFDMGEFKNSTKQADTKTSITDILNMDDEARDNYLRTMFPEFAPLSKEFTELAPKFDELKKSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNEDFTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQNSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPEADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKERLFERQQRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKISRKEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKRKKYQKAQKKLKS-VRAVYSGGQSGVYEGEKTGIKKGLTRSVKFKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *: .: ... . : . : : :*** :. ** . :: . ::: . .: : : **. : **.:* ... . . :: : :. * :: * : * :: * : : . .*: :. . : : ::. **: * ::: :..: :. : . :. :.: * : :*.: : :.:* : ::*: .:. :: . : . . : : : .: : : * : : .: *: :. : .. :.:*.*.**: **:****:*:* **.***:* *:::* : :. ** * * * ** :**: *:.:*:*:: ", "identical_positions": 57, "similar_positions": 140, "identity": "9.03%" }, { "cls_id": "homologset.agr.SGD:S000002313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG62-1", "uniprot_id": "MSH5_RAT", "id": "Q6MG62-1", "name": "MutS protein homolog 5", "aln": "-----MAFRATPGRTPPGPGP--GVPSASFSSPQPAMAAPGGIEEE-----DEEEPAEIHLCVLWSSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDEAMTQFLGKLASQEHREPKRPEIILLPSVDFGPEISKQRLLSGNYSFISESMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRR--VGVELEDYSVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCRCRWGQKLLRLWFTRPTRELRELNSRLDVIEFFLMPQNLDMAQMMHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFRDITQEFSD-DLHHIASLIGKVVDFEESLAENRFTVLPNIDPEIDAKKRRLMGLPSFLTEVAQKELENLDSCIPS------------CSVIYIPLIGFLLSIPRLSFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDALLGDLHCEIRDQEMLLMHQLQCQVLARAPVLTRVLDLASRLDVLLALASAARDYGYSRPHYSPCIQGVRIKNGRHPLMELCARTFVPNSTDCGG-----------DQGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLTAVLRHWLALGPSCPHIFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGNDLVFFYQLCHGVASASHASYTAAQAGLPDPLIARGKEVSDSIRSGKPVKPMHELVRRTQM---ENCQALVDKFLKLDLEDPSLDLDIFISQEVLPAATTIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUM7-1", "uniprot_id": "MSH5_MOUSE", "id": "Q9QUM7-1", "name": "MutS protein homolog 5", "aln": "-----MAFRATPGRTPPGPGPRSGIPSASFPSPQPPMAGPGGIEEE-----DEEEPAEIHLCVLWSSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDEAMTRFLGKLASEEHREPKGPEIILLPSVDFGPEISKQRLLSGNYSFISDSMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRR--IGVELEDYDVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCRCKWGQKLLRLWFTRPTRELRELNSRLDVIQFFLMPQNLDMAQMLHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFQDIAQEFSD-DLHHIASLIGKVVDFEESLAENRFTVLPNIDPDIDAKKRRLIGLPSFLTEVAQKELENLDSRIPS------------CSVIYIPLIGFLLSIPRLPFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDTLLGDLHCEIRDQETLLMYQLQCQVLARASVLTRVLDLASRLDVLLALASAARDYGYSRPHYSPCIHGVRIRNGRHPLMELCARTFVPNSTDCGG-----------DQGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLAAVLRHWLALGPSCPHVFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGEDLVFFYQLCQGVASASHASHTAAQAGLPDPLIARGKEVSDLIRSGKPIKATNELLRRNQM---ENCQALVDKFLKLDLEDPTLDLDIFISQEVLPAAPTIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43196-1", "uniprot_id": "MSH5_HUMAN", "id": "O43196-1", "name": "MutS protein homolog 5", "aln": "----MASLGANPRRTPQGPRP--GAASSGFPSPAP-VPGPREAEEEE--VEEEEELAEIHLCVLWNSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDENMTRFLGKLASQEHREPKRPEIIFLPSVDFGLEISKQRLLSGNYSFIPDAMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRRR--IGVELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFRDIAQEFSD-DLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPS------------CSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGG-----------DKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQM---ENCQTLVDKFMKLDLEDPNLDLNVFMSQEVLPAATSIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4N7-1", "uniprot_id": "A0A8M2B4N7_DANRE", "id": "A0A8M2B4N7-1", "name": "MutS protein homolog 5", "aln": "------MYRVADDSILPQPES----------------RAPSVMNED-----EDGRNREIILSVLLKQGNIGLSYYDSRDYTLHYMP-------------------DTVENSDLYLLDRVIQELSPTVIISSAKQEQCLVRFLEKLES--NCDEYKPEIVIFPSANFGVEVSKQRLISAHLPLLSSTITESEKILYISSCIPLDSGVMVRSIGGLLKCVEKRR--IGSELEDNDVGIPILQFLTYTLQDVVYIDRDTYSALQIFKSELHPSVLKLQSGVKEGLSLYGILNQCRSKYGSLLLRQWLHRPTRDLNILNRRQEVIRFFTSPRNFADLCTLQSCLRSIKNISMLLHKMSLCNPKVAVWQSLYKTVYSAVCIRDTIRSLPQS---IQLFREISENFTD-DLFYIATYISKVVDFEGSISENRFTVRPNVDPVIDEKKRRMMGLPDFLTDVARAELENLDPRFST------------CSVIYMPLIGFLLTVPRLPSMLDKQSFEIAGLDFIFLSKDQLHYRSTRTKELDSMLGDLHCDILDLEMAVMRKLQASVLQRSDCMYKVMSLCAELDCLIALAQASREHGYCCPILTTEHRLALIES-RHPLLELCTSVFVSNTYISSE-----------TEGKVKVITGPNSSGKSIFLKQVGLIVFMALIGSNVPAKEAEIGLVDGIFTRMHSRESISVGLSTFMIDVNQMAHSLNHSTENSLVLVDEFGKGTNTVDGLSLLVSCLSHWLRRGLQCPHLLMSTCFHSLIQLGLIPD-----------------SSLLALLTLETAIEGDELVFLYQVKNGICQSSCAANIATLAGIPDDLVRRGVEVSDLYRTGRTIRKMERPSADEQN---NRCAEIVEKFLSIDLDDPELDPDLLLKDQMLPALEEVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12175-1", "uniprot_id": "MSH5_YEAST", "id": "Q12175-1", "name": "MutS protein homolog 5", "aln": "MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKRFKKWDL---LQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMR--NGFFSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDG-IPNLQWEEIFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLN-MSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGEDHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCGNLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: . ** :.: . * :* : * *:: : * .:. ** :: * .* : .*: :: : :: . . : * : . :: :.. :* . . : . : ..*: : .... : : * : : .* : . * : : . : :*.:* *.*:** : : . *: : :*:: ::*: . :. :*: *: .* : :. * .:*. : :* : : : ::::: :..:. *. : . : ..: : : ** . :::::* ::. * : .*:**: * : :*: ..:* :* :. * .:* :**: * :. ..:*:* :*:*:::. * : : : :* *.::::::. *. *** **:: * * * :: .** .:* * : * :.*: *:::*..: : .*. * * . **.* * ::.*: . :*:: *:**.*:****::*.* ***.::* :*. ***:.*.** * *:**::: *:: *:*::* :*:*:::. :* :**:*:**:****: :** :*: : : : : . **::: .* * .*.: ::.: *: : :.: :.*:::: .*:.. * . * .*:. :: *. *:* . * : : :. :*.**:. **: . : :: ", "identical_positions": 148, "similar_positions": 287, "identity": "16.25%" }, { "cls_id": "homologset.agr.SGD:S000002314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24860-1", "uniprot_id": "CCNB1_MOUSE", "id": "P24860-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "--------------------------------------------------------------------MALR---------------VTRNTKINAENKAKVSMAGAKRVPVTVTAASKPG-LRPRTALGDIGNKVSEELQARVP-LKREAKTLGTG--KGTVKALPKPVEKVPVCEPEVELA---EPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLQG-REVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNS-CVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYSEDSLLPVMQHLAKNVVMVNCGLTKHMTVKNKYAASKHAKISTLAQLNCTLVQNLSKAVTKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30277-1", "uniprot_id": "CCNB1_RAT", "id": "P30277-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "--------------------------------------------------------------------MALR---------------VTRNTKINTENKAKVSMAGAKRVPVAV-AASKPL-LRSRTALGDIGNKVSE--QSRIP-LKKETKKLGSG--TVTVKALPKPVDKVPVCEPEVELD---EPEPEP----VMEVKHSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGGDPNLCSEYVKDIYAYLRQLEEEQSVRPKYLLG-REVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDS-CVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSHTEESLLPVMQHLAKNIVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVTKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14635-1", "uniprot_id": "CCNB1_HUMAN", "id": "P14635-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "--------------------------------------------------------------------MALR---------------VTRNSKINAENKAKINMAGAKRVPTAPAATSKPG-LRPRTALGDIGNKVSEQLQAKMP-MKKEAKPSATG--KVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILA-VNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLG-REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNN-CVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "id": "P20439-1", "name": "G2/mitotic-specific cyclin-B", "aln": "MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVP-TKTTVEPTKVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAK--LARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24870-1", "uniprot_id": "CG23_YEAST", "id": "P24870-1", "name": "G2/mitotic-specific cyclin-3", "aln": "--------------------------------------------------------------------MHHN---------------SQSLSSGHIRSPEDENVAPIGNLKHRTGSLSHISSAHPRVALSDVTNIVATN-SSNNSISKPKVAPIKER--LDSAAIIEEERLDANSVAQRKEADHNDLLTDREQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLD----PNDDDVYDVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKE-VVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHRLVSAQPSWLAAGAYFLSKIILG----------QNQWSLAHVYYSNYTQEQILPLATIILEN---CRYASKRHNAIWRKYSSRRYLHSSQIVAKWIALAEHRVERSN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . . . .: :. . .: : . . . * : : : . . . . . : : : * : :* : : :* ::*: *: ::* . :: *: .:*: ****: :*: :*:* **: : : ****:: . . :****.:::***:****: * * **.::::: *: .:: : * *:. :: *. * *: **** ** : : :*::**::* : :*: :. ** :**.: *: :*. : .*: : .* :: : *: : : : :: .** :. : : :* : ", "identical_positions": 66, "similar_positions": 122, "identity": "12.38%" }, { "cls_id": "homologset.agr.SGD:S000002315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJT1-1", "uniprot_id": "D3ZJT1_RAT", "id": "D3ZJT1-1", "name": "WD repeat-containing protein 76", "aln": "MSGFIAVAEEKAGSKQCPQVQVNEYKENENIAYTSLRPIQITTRRKAAKVYLYPFSLSNPKLGLFKLSKSPVENKSSSEMVQKKTDQKKTCRRVLTSKMKALSSKAESCLLKPALDSHTESSELEHKSISDPVTPSVDMESS-----DEDSAPGPDDFSGLSPYERKRMKNIRENANFFASLQLAESAARLRGMIKKNQPPESKRKRPKKKENEVGCRRSMRLLKVDPLGVSLPASLTQPTLVEEET-PMIPPGPLEMIPENQDDCSELFKASLKTWAEMSQTSNEKTKKGLSSIKSYKASLSGMVVSEATIRKVTKGAISSVAIHPSGVRTLVAAGSKSGQVGLWDLT---------QQS-EDGAYAFCPHSQPVSCLSFSPTNPAHLLSLSYDGTVRCGDFSTAVFEEVY-----RNERNSLSSFDFLD-DASTLLVGHWSGHLSLVDRRTPGTSYEKFINSSLEKIRTVHVHPLSRQYFITAGLR-DVHVYDVRCLKSGK---------SQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSS---LSSQFPLVSTIRHNTITGRWLTRFQAVWDPKQEDCFTVGSMAHPRRVEVFHETGKNVHSFGG-ECLVSVCSLSVMHPTRYILAGGNCSGRLHVFMHQET------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6PWY4-1", "uniprot_id": "WDR76_MOUSE", "id": "A6PWY4-1", "name": "WD repeat-containing protein 76", "aln": "MSGSKAESEEKAGSKQCPLVQVNEYKENEHIAYTSLRPIQITTLRKTAKVYLYPFSLSNSKLGLLKLSKSPVVNNSSKSVVHKKKDRKKTRRKVLTSKMKALSSKADSLLLKSSVDAYTESTRLGPKRTSDSATLSVDAESS-----DEDSAPGLDDFSGLSPYERKRLRNIRENANFFASLQLAESAARLRGMIKKRESPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPASPTQPTLVEEEENPLLPPGPLEMIPENQDDSSELLKASLKTWAEMSQTSNEKTKKGLSSIKSYKANLSGMVISEATVRKVTKGAISSVALHPSEVRTLVAAGAKSGQIGLWDLT---------QQS-EDAMYVFYAHSRYVSCLSFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVY-----RNEGNSPSSFDFLN-DSSSLLVGHWDGHLSLVDRRTPGTSYEKFFNSSLEKIRTVHVHPLSRQYFVTAGLR-DVHVYDARFLKSRG---------SQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSS---ISSQLPLLSTIRHNTVTGRWLTRFQAVWDPKQEDCFIVGSMDHPRRVEVFHESGKNVHSLWG-ECLVSVCSLSAVHPTRYILAGGNSSGKLHVFMHQET------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H967-1", "uniprot_id": "WDR76_HUMAN", "id": "Q9H967-1", "name": "WD repeat-containing protein 76", "aln": "MSRS-GAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQLDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPSLD-FSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSKRKKPKR-ENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLVADET-PLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLT---------QQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVY-----RNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLR-DTHIYDARRLNSRR---------SQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSC---ISSKIPLLTTIRHNTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGG-EYLVSVCSINAMHPTRYILAGGNSSGKIHVFMNEKSC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q1Q9-1", "uniprot_id": "A0A8M9Q1Q9_DANRE", "id": "A0A8M9Q1Q9-1", "name": "WD repeat-containing protein 76", "aln": "------------------------------------------MDTDKSDLSLETMKLLQERTPPQNPGMDGSVLRTSRRIKEKQNQRKKQNLPPKCLTFRSEVKSTKRVVKRRISGSEKEKEVKRSKADPDHESLPQGYREG------------------LSEYQLERLENIRKNQAFLNSLNLTEISEALR---PKQKPTQKGLKKEKTQVEMLPVRKSLRLQNKGPQSTTATEFTFPTTYELEKE--AKPPGPIPLDPINLDEDATLPDDLLDVWNEVPLEQS----TGTPDLKSYERMLKKLSIDDSRVVKVVKERICCAAFHPSSN-LLMAAGDKYGHLGLWRPD---------AEWGDDGVVCFEPHSRAITALAFT-SQPCNLITASYDGSARSMDLEKAVFDEVY-----RSS-SSLKSFDFLSSDCSTLLFGEWNGDVAVVDRRT-GNLCESLHAMTAAPLRGVHVHPVQQHYFLVAESS-FVNIYDLRHLKKRN---------SPAVCELYGHNRSTSSAFFSPLTGSRVLTTCMDDCIRVFDSSQ---IAGRIPALTSIRHNMQTGRWLSRLCAVWDPKHQECFVIGTMDRPRKIKVYHESGRLLHTLQNTEHLTTVCSVTAFHPSRNALLGGNASGRLHIYTD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12510-1", "uniprot_id": "CMR1_YEAST", "id": "Q12510-1", "name": "DNA damage-binding protein CMR1", "aln": "----------------------------------------MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKSRAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDG-------------------------------QDKNFIDAIK------------EKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSS-----------------------------------GDFFEEIKKRQGDVT------------GMDEFDLDLYDVFQPNE--IKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRDEPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQSEEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYN-LRRLADKKIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLSVSAVSYSPTDG-TLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKARFKP-NKNVFAIANMK--RAIDIYNSEGQQLAHLPT----ATVPAVISWHPLRNWIAGGNSSGKIFLFTDDSGTIKQEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :. : . . : *. * . : . . * . .. :: *: ::: * . . : ..:: : . . . . :. .:..:. * : : *:. * . :**: *: .* . * :*: . : . .:: : : ::..::: ****: *. .:. :** .. . .. :* : . *:. .*..: .* *. . : : : : : ::*: : .. :::* * * . * : . * ::. :** * :: . * :*:** . ::.:: :*:** **** : : * :.* ::: . :..* * :.:::. *: : : .:* :: ** * : ***.**::.:: . ", "identical_positions": 61, "similar_positions": 158, "identity": "9.2%" }, { "cls_id": "homologset.agr.SGD:S000002318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31938-1", "uniprot_id": "MP2K1_MOUSE", "id": "P31938-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "-----------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG-------------------TSSAETNLEALQKKLEELELDE------------QQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKKAGRIPEQ-------------ILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFG----CHVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKR--SDAEEVDFAGWLCSTIGLNQPSTPTHAASI---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01986-1", "uniprot_id": "MP2K1_RAT", "id": "Q01986-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "-----------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG-------------------TSSAETNLEALQKKLEELELDE------------QQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKKAGRIPEQ-------------ILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFG----CQVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKR--SDAEEVDFAGWLCSTIGLNQPSTPTHAASI---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02750-1", "uniprot_id": "MP2K1_HUMAN", "id": "Q02750-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "-----------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG-------------------TSSAETNLEALQKKLEELELDE------------QQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKKAGRIPEQ-------------ILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFG----CQVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKR--SDAEEVDFAGWLCSTIGLNQPSTPTHAAGV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63932-1", "uniprot_id": "MP2K2_MOUSE", "id": "Q63932-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "----------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS-------------------EGASEANLVDLQKKLEELDLDE------------QQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKP-AVRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKEAKRIPED-------------ILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSG-VFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKR--SEGEEVDFAGWLCRTLRLKQPSTPTRTAV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36506-1", "uniprot_id": "MP2K2_RAT", "id": "P36506-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "----------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS-------------------EGASEAHLVDLQKKLEELDLDE------------QQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKP-AVRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKEAKRIPED-------------ILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPSG-VFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKR--SEGEDVDFAGWLCRTLRLKQPSTPTRTAV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36507-1", "uniprot_id": "MP2K2_HUMAN", "id": "P36507-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "----------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS-------------------EGASEANLVDLQKKLEELELDE------------QQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFYS---DGEISICMEHMDGGSLDQVLKEAKRIPEE-------------ILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVS-GHGMDSRPAMAIFELLDYIVNEPPPKLPNG-VFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKR--SEVEEVDFAGWLCKTLRLNQPGTPTRTAV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24324-1", "uniprot_id": "DSOR1_DROME", "id": "Q24324-1", "name": "Dual specificity mitogen-activated protein kinase kinase dSOR1", "aln": "-----------------------------------------------------------------------------------------MSKNKLNLVLPPVNTEATVAAATVAPTPPFKTPSGTDT---HSLLGKPKTSIDALTETLEGLDMGD------------TERKRIKMFLSQKEKIGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKP-AIKKQILRELKVLHECN-FPHIVGFYGAFYS---DGEISICMEYMDGGSLDLILKRAGRIPES-------------ILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFA---------DNAEESGQP------------TDEPRAMAIFELLDYIVNEPPPKLEHK-IFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRK--AELEEVDISGWVCKTMDLP-PSTPKRNTSPN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06784-1", "uniprot_id": "STE7_YEAST", "id": "P06784-1", "name": "Serine/threonine-protein kinase STE7", "aln": "MFQRKTLQRRNLKGLNLNLHPDVGNNGQLQEKTETHQGQSRIEGHVMSNINAIQNNSNLFLRRGIKKKLTLDAFGDDQAISKPNTVVIQQPQNEPVLVLSSLSQSPCVSSSSSLSTPCIIDAYSNNFGLSPSSTNSTPSTIQGLSNIATPVENEHSISLPPLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGG------------------------------------------HNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLIMKYVSPSKDDKFRHWCRKIKSKIKEDKRIKREALDRAKLEKKQSERSTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.: :. ..: . . : : * : :: . :: *: . : . :. :*: ::.::*:**.*.* *. * ::*:* * :* : :: :*::***.:::: : *: ****:*. :.** * **: * **** :*. *: : :.::: .*:.** :* :: *:***:****:*:** *:**:****** :**:*:*::**** :**:***:**. **::.*:**:** ::*:. * :*: .. . .*::**: *****.*:* ::: :: :**: * *: **:.:: * * * : : :: .: * .. : ", "identical_positions": 105, "similar_positions": 129, "identity": "18.85%" }, { "cls_id": "homologset.agr.SGD:S000002319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54823-1", "uniprot_id": "DDX6_MOUSE", "id": "P54823-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKASAGPGGGGTQPQP-QLNQLKNTSTINNGTPQQAQSMAATIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPAE----DEKP----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD73-1", "uniprot_id": "D3ZD73_RAT", "id": "D3ZD73-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKASAGPGGGGPQTQT-QMNQLKNTSTINNGTQQQAQSMAATIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPAE----DEKP----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26196-1", "uniprot_id": "DDX6_HUMAN", "id": "P26196-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKPTGGPGGGGTQTQQ-QMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVE----DEKP----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FD91-1", "uniprot_id": "E7FD91_DANRE", "id": "E7FD91-1", "name": "RNA helicase", "aln": "MSTARMENPV-ILGLSNQNGQMRGSVKPAGGPGGGGGGSQTTQPAQVKASSTVNNGNSQPVPTANTIIKPGDDWKKNLKLPPKDLRMKTSDVTATKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERIDLKKDSIQAVVIVPTRELALQVSQICIQVSKHMGGVKVMATTGGTNLRDDIMRLDETVHVVIATPGRILDLIKKGVAKVGQVQMIVLDEADKLLSQDFVQMMEEILSSLSKQRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLGETYLHRIGRSGRFGHLGLAINLITYDDRFNLKGIEEQLGTEIKPIPSSIDKSLYVAEYHSESGE----EVKL----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1G8-1", "uniprot_id": "E7F1G8_DANRE", "id": "E7F1G8-1", "name": "RNA helicase", "aln": "MATARTEIPASVMPVTKQNGQAKPMSLQTGSFSSSTPSGKTPVMPQKGSSIPQSSGG----------IRFGDDWKKCLQLPPKDTRVRTTDVTATKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERIDLKKDYIQAIVLVPTRELALQVSQISINMSKHLGGIKVMATTGGTNLRDDIMRLDEIVHVIIATPGRILDLIKKGVAKVDKVQMAVMDEADKLLSQDFVVLIEDIISFLPKKRQILLYSATFPISVQKFMTKHLQKPYEINLMDELTLKGITQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSTQRVELLAKKITQLGYSCFYIHAKMMQEYRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLITSEDRFNLKGIEDQLMTDIKPIPSSIDKSLYVAEFHSMNPD----EEEAAHKTGELN--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23128-1", "uniprot_id": "DDX6_DROME", "id": "P23128-1", "name": "ATP-dependent RNA helicase me31b", "aln": "-----------MMTEKLNSGHTNLTSKGIIN------------DLQIAGNTSDDMG-----------------WKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKHLD-IRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINLMEELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIPKVIDPALYVANVGASVGD----TCNNSDLNNSANEEGNVSK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39517-1", "uniprot_id": "DHH1_YEAST", "id": "P39517-1", "name": "ATP-dependent RNA helicase DHH1", "aln": "------------MGSINNNFNTN-----------------------NNSNTDLDR-----------------DWKTALNIPKKDTRPQTDDVLNTKGNTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLEKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCG-ISCMVTTGGTNLRDDILRLNETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFSATFPLTVKEFMVKHLHKPYEINLMEELTLKGITQYYAFVEERQKLHCLNTLFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGTEIAAIPATIDKSLYVAENDETVPVPFPIEQQSYHQQAIPQQQLPSQQQFAIPPQQHHPQFMVPPSHQQQQAYPPPQMPSQQGYPPQQEHFMAMPPGQSQPQY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : . . . **. *::* ** * :* ** *:** **:: *********** *:*:****** :**:*::*:*:**********:.*: ** **::. . : ***:::*********.**: :.** . *.***** *:***:*: : *::::.****:*** .: **.:.. : ::*****:** ** :::.:: *. * **:*****::*::** .**::*******:******:*****:* ****:********:*****:******::*********::***.*:* **:* * **:***:**:* *.***:**:*****:************: .************:****:*****. :***:* **.:* *:* .** ** :****: : ", "identical_positions": 243, "similar_positions": 108, "identity": "43.47%" }, { "cls_id": "homologset.agr.SGD:S000002320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V882-1", "uniprot_id": "EPN3_RAT", "id": "Q4V882-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIG----SGQLGFSR-------------RSRGSPSSYTSA--------------------------------------------------------SSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAE---------------------------KGGRSWKGDDFPVANGAEPAG---QRR-RDREPEREERKEEEKLKTSQSSILDLADVFAPAP--ALPSTHCSADPWDIPGLRPNTEPSG---SSWGPSADPWSPVPSG-NALSRSQPWDLLPTLSSSEPWGR-TPVLPSG-PPITDPWAPSS------------------------------------PTPKLPSTGVDPWGASVETSNTSALGGASPFDPFAKPLESTE-------------PMESRDSAQALPKGKSPSPVELDPFGDSSPSCKQNGVKETEALDLGVLG---------EALTQQPGKEARPCRTPESFLGPSASSLVNLDSLVK---APLAA----RTRNPFLT-GLSAP--SPTNPFGAGEQGRPTLNQMRTGSPALGLPPGGPVGVPLGS---MTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPA----------------------------------------------------------------------SLPQPLLPTSDPVG-------------------------------------------------------------------------PLPPQAGTNPFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W69-1", "uniprot_id": "EPN3_MOUSE", "id": "Q91W69-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIG----SGQLGYSR-------------RSRGSPSSYTSA--------------------------------------------------------SSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSPVANGAEPAG---QRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAP--ALPSTHCSADPWDIPGLRPNTEPSG---SSWGPSADPWSPVPSG-NALSRSQPWDLLPTLSSSEPWGR-TPVLPSG-PPIADPWAPSS------------------------------------PTRKLPSTGADPWGASMETSDTSALGGASPFDPFAKPLESTE-------------PKESRDSAQALPTGKSPSTVELDPFGDSSPSCKQNGMKEPEALDLGVLG---------EALPQQPGKEARPCRTPESFLGPSASSLVNLDSLVK---APLAA----RTRNPFLT-GLGVP--SPTNPFGAGDQGRPTLNQMRTGSPALGLPPGGPVGAPVGS---MTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPA----------------------------------------------------------------------SLPQPLLPTSGPMG-------------------------------------------------------------------------PLPPQAGTNPFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H201-1", "uniprot_id": "EPN3_HUMAN", "id": "Q9H201-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIG----SGQLGFSRR------YGEDYSRSRGSPSSYNSS--------------------------------------------------------SSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVV---HHQ-RDREPEREERKEEEKLKTSQSSILDLADIFVPAL--APPSTHCSADPWDIPGFRPNTEASG---SSWGPSADPWSPIPSG-TVLSRSQPWDLTPMLSSSEPWGR-TPVLPAG-PPTTDPWALNS------------------------------------PHHKLPSTGADPWGASLETSDTP--GGASTFDPFAKPPESTE-------------TKEG--LEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILG---------EALTQ-PSKEARACRTPESFLGPSASSLVNLDSLVK---APQVA----KTRNPFLT-GLSAP--SPTNPFGAGEPGRPTLNQMRTGSPALGLA-GGPVGAPLGS---MTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAP----------------------------------------------------------------------------QPLLPTPSSAGPR-----------------------------------------------------------------------PPPPQTGTNPFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHU3-1", "uniprot_id": "EPN2_MOUSE", "id": "Q8CHU3-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGS---------------------------------------------------------TSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQS---------------SESVQTARGSKEERLRRGDDLRLQMALEESR---RDT--VKVPKKKEAKACCKPGSHSQQTTLLDLMDALPS--SGPVTQKT-EPWSAG--------------ASANQTNPWGGTVAP-SNITDPWPSFGTKPAASVDPWGVPTTASTQSVPKNSDPWAASQQ-----------------------------------PASNAGK-TTDAWGAA---KPSSASGSFELFSNFNG---------------------TVKDDFSEFDNLRTSKKPAESGA---SVPPQDSRTTSPDLFESQ------------SLTSASSKPSS-ARKTPESFLGPNAA-LVNLDSLVT---KPAPP---AQSLNPFLAPGAAAP--APVNPFQVNQPQPLTLNQLR-GSPVLGSSASFGSGPGVET--VAPMTSVAPHSSVGASGSSLTPLGPTAMNMVGSVGIP----------------------------------------------------------------------------PSAAQ---------------------------------------------------------------------------------STGTTNPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1Z3-1", "uniprot_id": "EPN2_RAT", "id": "Q9Z1Z3-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNSYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSISHSEQEYGKAGGSPASYHGS---------------------------------------------------------TSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ---------------------------EERLRRGDDLRLQMALEESR---RDT--VKVPKKKEVKACCKPGSHSQQTTLLDLMDALPS--SGPVAQKT-EPWSTG--------------TPANQTNPWGGTVAP-ANISDPWPSFGTKPAASVDPWGVPTTASIQSVPKNSDPWAASQQ-----------------------------------PASDAGK-TADAWGAA---KPSPASGSFELFSNFNG---------------------TVKDDFSEFDNLRTSKKPAESGA---SVPPQDSRTTSPDLFESQ------------SLTSASSKPSS-ARKTPESFLGPNAA-LVNLDSLVT---KPAPP---AQSLNPFLAPGAAAP--APVNPFQVNQPQPLTLNQLR-GSPVLGSSASFGSGPGVET--VAPMPSVAPHSALGATGSSLTPLGPTAMNMVGSMGIP----------------------------------------------------------------------------PSAAQ---------------------------------------------------------------------------------PAGTTNPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95208-1", "uniprot_id": "EPN2_HUMAN", "id": "O95208-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPNGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ---------------------------EERLRRGDDLRLQMALEESR---RDT--VKIPKKK------EHGSLPQQTTLLDLMDALPS--SGPAAQKA-EPWGPS--------------ASTNQTNPWGGPAAP-ASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNSDPWAASQQ-----------------------------------PASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNG---------------------TIKDDFSEFDNLRTSKKTAESVT---SLPSQNNGTTSPDPFESQ------------PLTVASSKPSS-ARKTPESFLGPNAA-LVNLDSLVT---RPAPP---AQSLNPFLAPGAPATS-APVNPFQVNQPQPLTLNQLR-GSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVGIP----------------------------------------------------------------------------PSAAQ---------------------------------------------------------------------------------ATGTTNPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80VP1-1", "uniprot_id": "EPN1_MOUSE", "id": "Q80VP1-1", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATAS-----SAAVGSGPP----PEAEQAWPQSSGEEELQLQL----------------------------------------------------------ALAMSKEEADQPPSCGPEDDVQLQLALSLSREEHDK---------------------------EERIRRGDDLRLQMAIEESK---RETGGKEESSLMDLADVFTTPAPPQASDPWGGPASVPT--AVPVAAAASDPWGGP--------------AVPPAADPWGGAAPT-PASGDPWR-PAAPTGPSVDPWGG-TPAPAAGEGPTPDPWGSSDG-----------------------------------GAPVSGPPSSDPWAPAP--AFSDPWGGSPAKPSSNG-TAVGG-------------FDTEPDEFSDFDRLRTALPTSGSSTGELELLAGEVPARSPGAFDMSGVGGSLAESVGSPPPAATPTPTPPTRKTPESFLGPNAA-LVDLDSLVS---RPGPTPPGSKASNPFLPSGAPPTGPSVTNPFQPAPPATLTLNQLR-LSPVP--------------------------PVPGAPPTYISPLG-------GGPGLP----------------------------------------------------------------------------PMMPPG-------------------------------------------------------------------------------PPAPNTNPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88339-1", "uniprot_id": "EPN1_RAT", "id": "O88339-1", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATAS-----SAAVGSGPP----PEAEQAWPQSSGEEELQLQL----------------------------------------------------------ALAMSKEEADQPPSCGPEDDVQLQLALSLSREEHDK---------------------------EERIRRGDDLRLQMAIEESK---RETGGKEESSLMDLADVFTTPAPPQASDPWGGPASVPT--AVPVAAAASDPWGAP--------------AVPPAADPWGGAAPT-PASGDPWR-PAAPTGPSVDPWGG-TPAPAAGEGPTSDPWGSADG-----------------------------------GAPVSGPPSSDPWAPAP--AFSDPWGGSPAKPSSNG-TAVGG-------------FDTEPDEFSDFDRLRTALPTSGSSTGELELLAGEVPARSPGAFDMSGVGGSLAESVGSPPPAATPTPTPPTRKTPESFLGPNAA-LVDLDSLVS---RPGPTPPGAKASNPFLPSGAPATGPSVTNPFQPAPPATLTLNQLR-LSPVP--------------------------PVPGAPPTYISPLG-------GGPGLP----------------------------------------------------------------------------PMMPPG-------------------------------------------------------------------------------PPAPNTNPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6I3-2", "uniprot_id": "EPN1_HUMAN", "id": "Q9Y6I3-2", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATAS-----SAAVGSGPP----PEAEQAWPQSSGEEELQLQL----------------------------------------------------------ALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDK---------------------------EERIRRGDDLRLQMAIEESK---RETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAA--AVPTAAPTSDPWGGP--------------PVPPAADPWGGPAPT-PASGDPWR-PAAPAGPSVDPWGG-TPAPAAGEGPTPDPWGSSDG-----------------------------------GVPVSGPSASDPWTPAP--AFSDPWGGSPAKPSTNGTTAAGG-------------FDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA-LVDLDSLVS---RPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVP--------------------------PVPGAPPTYISPLG-------GGPGLP----------------------------------------------------------------------------PMMPPG-------------------------------------------------------------------------------PPAPNTNPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS85-1", "uniprot_id": "Q9VS85_DROME", "id": "Q9VS85-1", "name": "", "aln": "MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFG----SDGYIDGPS-------------QRDLPPGWQEE----------------------------------------------------------PPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQ---------------------------EEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGN--GGINSSMHPSTGATAKKSIKDAHSFLGENSA-LVNLDNLIKP-IAPQTQTGNQPAYNPFSDNVVPPK----TNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGG--VSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9Q1Z2-1", "uniprot_id": "E9Q1Z2_MOUSE", "id": "E9Q1Z2-1", "name": "", "aln": "------------MSFRRQVKNFVKNYSDAEKKVREATSNDPWGPSSSLMLAISDMTFNAASLSEIMHMLWQRLSDHGKNWRHVYKSLALMDYLIKNGSRKVIQYCREGVCNLQMLKDFQHIDEAGKDQGHYIRERSKQVITLLMDEQLLHKEREVATWTRQRTSYSMSFPS-----RLSATGTS--------PTVCTSVLIPESLTSE-----------------------------------------------------------KKHSQDCKKTAGLCSKKNTSKARLRLEQCQDVPSP---------------------------AGTSLPLYFPSLGMKAWKSTEDLTLLYSYEHPKQPVTRLPPSFTSPASWLSEGEAEICNLWDTEAVSTPPEKNPSMQTSVSLGKKLES----AIANTITESPPQTPQEKQMAAKSFEMPTPLPAFWPSGKDEFVSLALRMSKSESIFHTQSS--------------------------------VETLYVSPTFKTISPLNET--SQDLQTPAQFSICQMEDVCLKPLAMRGEWTPKQASEAVSAASEVASSFSTLSISPPDLAHPEKSARCFIPVMASSSFWTLPQPQS----------PSDPLTDQNEAVRVRHPFAPTSTASSDNEEYPSL------PDNSDSTMKEPSYSFSSGRGAFSTLTRAHFPGLPQASFRFQESAGLSRDSESR-AICTLLGEVKS-----AVVRLHDDLSLVIQELSVINSRLGNLSGSSPTVSE-------------------------------------------------------------------------TLQDPQS--------------------------------------------------------------------------------PRGSPDPV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYW4-1", "uniprot_id": "ENTD1_HUMAN", "id": "Q8IYW4-1", "name": "ENTH domain-containing protein 1", "aln": "------------MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRLNDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIREKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSK-----RQLGSSNS--------LTACTSAPTPDISASE-----------------------------------------------------------KKY--KLPKFGRLHNKRNVCKAGLKQEHCQDVHLP---------------------------TETMLSQETLPLKIHGWKSTEDLMTFLD-DDPELPLLATPPSIVSPITCLSEA-EEVCNLSGADAVPTLSENSPSGQRDVSLDKRSDG----IFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSS-KEEFISPDLRVSKSDSTFHNQAS--------------------------------VETLCLSPSFKIFDRVKEIVINKAYQKPAQSSI-QMDDKILK------------TTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQL----------SSTSFKDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQF--IPLSCSGFQSTKDFPQEPEAKNSISVLLREVKR-----AIARLHEDLSTVIQELNVINNILMSMSLNSSQISQ-------------------------------------------------------------------------SSQVPQS--------------------------------------------------------------------------------SEGSSDQI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12518-1", "uniprot_id": "ENT1_YEAST", "id": "Q12518-1", "name": "Epsin-1", "aln": "----------MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGTG-------------------------------------------------------------------------------------------------------------RSDENDDDLQRAISASRLTAEE----------------------------DERRRKQDEDYETALQLSK---------EEEELKRLQDLQRMQQQQGQQQLQQPMYYDIFG---------------------------------NPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPEELAQFQQQQQLQEQQY-----------------------------------------LASMQQQQQAMSNNPFAKSEQSSSSPKRNQ--------------------LVAASSPQQLQQQKQQEPLIQNRTGNQSMTDKYSKLNELLATGTGID----------TFGNVGEARIPAQHTKTGTFINSQGTGYRQVSDDPN--------------HNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQQQS--------------------------------QNNGSNNRGYTLIDL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. **:.:.**.:: **:***** . : ::: ::: : *:* *: :**.* ** ***: *:: :::**:: **.. *:*.. :: *::* : : * *** :* : *:: :** *: * ** ::: . .: . .: . . : . : . .: : . . :. . ", "identical_positions": 44, "similar_positions": 71, "identity": "4.66%" }, { "cls_id": "homologset.agr.SGD:S000002323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHY8-1", "uniprot_id": "DNLI1_RAT", "id": "Q9JHY8-1", "name": "DNA ligase 1", "aln": "MQRSIMSFFQPTTTEGKAKKPEKEIPSSIREKEPPPKVALKERNRAVPESDSPVKRPGRKVAQVLSSEGEDEDEAPGTPQVQKPVSDSKQSSPPSPDSCPENSPVFNCSPSMDISPSGFPKRRTARKQLPKRTIQDTLEEPNEDKAKAVKKRKKEDP-QTPPESLTEAEEVNQKEEQVEDQPTVPPEPTESPESVTLTKTENIPMCKAGVKQKPQEEEQSKPPARGAKPLSSFFTPRKPAVKTEVKQEESDTPRKE-ETKGAPDPTNYNPSKSNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPTDLLPVLYLSLNRLGPPQQ-GLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPSPPLTVSGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRYSEARFIARSLSGRLRLGLAEQSVLAALAQAGSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLESLPEHCKLSPGVPLKPMLAHPTRGVREVLKRFEEVDFTCEYKYYGQRAQIHVLEGGEVKIFSRNQEDNSGKYPDIISRIPKIKHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLARQPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLD-VDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGRGKRPGRYGGFLLAAYDEESEELAAICKLGTGFSDEELEEHHQNMQALLLPTPRPYVRIDGAVAPNHWLDPSIVWEVKCADLTLSPIYRAARGMVDKEKGISLRFPRFIRVREDKQPEQATTSDQVASLYRKQSQIQNQQSSDLDSDVEDY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37913-1", "uniprot_id": "DNLI1_MOUSE", "id": "P37913-1", "name": "DNA ligase 1", "aln": "MQRSIMSFFQPTK-EGKAKKPEKETPSSIREKEPPPKVALKERNQVVPESDSPVKRTGRKVAQVLSCEGEDEDEAPGTPKVQKPVSDSEQSSPPSPDTCPENSPVFNCSSPMDISPSGFPKRRTARKQLPKRTIQDTLEEQNEDKTKTAKKRKKEE--ETPKESLAEAEDIKQKEEKEGDQLIVPSEPTKSPESVTLTKTENIPVCKAGVKLKPQEEEQSKPPARGAKTLSSFFTPRKPAVKTEVKQEESGTLRKE-ETKGTLDPANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQ-GLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGGEVKIFSRNQEDNTGKYPDIISRIPKIKHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLD-VDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYRKQSQIQNQQSSDLDSDVEDY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18858-1", "uniprot_id": "DNLI1_HUMAN", "id": "P18858-1", "name": "DNA ligase 1", "aln": "MQRSIMSFFHPKK-EGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGIPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVATKQELQ-EEEEQTKPPRRAPKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQ-GLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLD-VDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1H4-1", "uniprot_id": "DNLI1_DROME", "id": "Q9W1H4-1", "name": "DNA ligase 1", "aln": "MQKSITSFFKKKSDATDSPSPPKKVPKIDAKTELPDEPHIK------SESASPETKP----------------------KVEPMSVDSEEKTSP---------------------------------------VKNVKKEPKEVDDKTTDKK-----------------------------------------------------------------------------VTTIGLNSTAATKEDVEN--------------------YDPSADSYHPLKNAYWKDKKVTPYLALARTFQVIEETKGRLKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYE-GLELGVAETTLMKAICKATGRNLAHIKSQTQLTGDLGIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQS----KMDLVYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTALAIGLVKKN-------HIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAILKYDIKELQERCPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGERAQIHRNEKGEISIFSRNSENNTAKYPDLIARSTALLKGDVKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLD-EEATYEIAKRSRNWLKLKKDYLSNVGDSLDLVVIGGYKGKGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQTHSEFLGKHVTSAAKSYYRYDPSLEPDHWFEPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQVAHMYQSQDQVKNNQKSSTQMEMEDEFY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04819-1", "uniprot_id": "DNLI1_YEAST", "id": "P04819-1", "name": "DNA ligase 1", "aln": "MRRLLTGCLLSSARPLKSRLPLLMSSSLPSSAGKKPKQATLARFFTSMKNKPTEGTPSPK-------------------KSSKHMLEDRMDNVSGEE------------------------------EYATKKLKQTAVTHTVAAPSSMGSN-----------------------------------------------------------------------------FSSIPSSAPSSGVADSPQQSQ---------------RLVGEVEDALSSNNNDHYSSN--IPYSEVCEVFNKIEAISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGENLLMKTISETCGKSMSQIKLKYKDIGDLGEIAMGARNVQPTMFKPKPLTVGEVFKNLRAIAKTQGKDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVLISLSKALLLHD---------ENREDSPDKDVPMDVLESAQQKIRDAFCQVPNYEIVINSCLEHGIMNLDKYCTLRPGIPLKPMLAKPTKAINEVLDRFQGETFTSEYKYDGERAQVHLLNDGTMRIYSRNGENMTERYPEINITDFIQDLDTTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKVKVCLFAFDILCYNDERLINKSLKERREYLTKVTKVVPGEFQYATQITTNNLDELQKFLDESVNHSCEGLMVKMLEGPESHYEPSKRSRNWLKLKKDYLEGVGDSLDLCVLGAYYGRGKRTGTYGGFLLGCYNQDTGEFETCCKIGTGFSDEMLQLLHDRLTPTIIDGPKATFVFDSSAEPDVWFEPTTLFEVLTADLSLSPIYKAGSATFD--KGVSLRFPRFLRIREDKGVEDATSSDQIVELYENQSHMQN---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : . : . .: * .. . : :. .. . : . : . . :::. . . .::: .: : : . . . :: :. *: :...*: ** ..**.:: *::: .:: *. :*:* ** :*:*.* : *****:.: *:*::.:: *:.: :: : **:* :* :* * *: . **. ** :: **: *. *:.:: ::.**: **::: *** .:**:*:**:::* :*: . : . :. : . :: ::*: *: : :* *::.: * : * : **:**:****:**:.: **:.** :*.*:** *:***:* : * : *:*** *: : :**:: ... *:* * **** :: :* *****:*****:*: .:::*:**:: **:: *. * : *..**: * : . **: ::* : *:: ::: :**::*:: .******* *: :: ** :***:**********..***:*** *:*.* *:*:*.* ******..*: :. * : **:****:** *: : : : .:. * : *: *::* ::** ***:****: *. . .* :*:*******:*:*.** *:** : *:. :*..*.:::* ", "identical_positions": 215, "similar_positions": 250, "identity": "23.27%" }, { "cls_id": "homologset.agr.SGD:S000002324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y9U2-1", "uniprot_id": "A0A8I5Y9U2_RAT", "id": "A0A8I5Y9U2-1", "name": "CCR4-NOT transcription complex subunit 2", "aln": "MIASSTVRKGHDSMVRTDGHTLSEKRNYQVTNSMFG---------ASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASP--STSGQLSQFG---------ASLYGQQSALG-LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHT-----------------PPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQPSRQPFTVNSMSGFGMNRNQA--FGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQ----SQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLSTSGKTTSSTDGPKFPGDK----SSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTN-TYERGTYYFFDCLNWRKVAKEFHLEYDKLE---ERPHLPSTFNYNPAQQAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5L3-1", "uniprot_id": "CNOT2_MOUSE", "id": "Q8C5L3-1", "name": "CCR4-NOT transcription complex subunit 2", "aln": "-------------MVRTDGHTLSEKRNYQVTNSMFG---------ASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASP--STSGQLSQFG---------ASLYGQQSALG-LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHT-----------------PPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQPSRQPFTVNSMSGFGMNRNQA--FGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQ----SQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLSTSGKTTSSTDGPKFPGDK----SSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTN-TYERGTYYFFDCLNWRKVAKEFHLEYDKLE---ERPHLPSTFNYNPAQQAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZN8-1", "uniprot_id": "CNOT2_HUMAN", "id": "Q9NZN8-1", "name": "CCR4-NOT transcription complex subunit 2", "aln": "-------------MVRTDGHTLSEKRNYQVTNSMFG---------ASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASP--STSGQLSQFG---------ASLYGQQSALG-LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHT-----------------PPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQPSRQPFTVNSMSGFGMNRNQA--FGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQ----SQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDK----SSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTN-TYERGTYYFFDCLNWRKVAKEFHLEYDKLE---ERPHLPSTFNYNPAQQAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA34-1", "uniprot_id": "A0A8M2BA34_DANRE", "id": "A0A8M2BA34-1", "name": "CCR4-NOT transcription complex subunit 2", "aln": "-----------------------MNVCSFVTNGMFG---------ATRKKF-DGVESDYPDESMYYNQASMFQHRSEKDMLPSPSPSSSGQLSQLG---------ASLYGPQSALG-FSIRGMSNNNPQLNRSLTQGTQLPSHSTPTTGVPTMSLHTT----------------PPSPNRGILPMNTRNMMS-SQVGQGMGMSGRTNSMGSSGLGSPNRSSPSIICMPKQQPARQPFTINSMSGFGMGRSQG--FGMN-SLSNNIFNGTDGSENVTGIDLSEFPALADRSRREGNGNPTPLHNPLAGRAPYVGMVTKPSNEQ----SQDFSIHNEDFPALPGPNYKDPTLSTDESKSSLNSSGKGSSSADGPKFPGDK----TSSAQNNNQQKKGIQVLPDGKVTNIPSGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASAPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDLLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTLKTN-TYERGTYYFFDCHNWRKVAKEFHLEYDKLE---ERPHVPTTFNYNPAQQAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94547-1", "uniprot_id": "RGA_DROME", "id": "Q94547-1", "name": "Regulator of gene activity", "aln": "---------MANLNFQQPPRSIANAALAGRTTGGFGGSSLAGHVTPTSGMFQTDFANSYPG-TANYGQAPQQQQQQQQQPQLSP--NRNAQLSVGGPAISSGNRNANLFGQRQFVERRAMQGLGSGPMSNMGNFMQTGRGGYGTGGGGGGPLNNFHVFGGGGGSDTSTPALLDPTEFPSLTNARGQNDQTLPQSNPLQPPGSKPYGNFFTSFGMVKQPTSEQSEFTMSNEDFPALPGTQNSDGTTNAVGSVAGTGGSGGASTENHLDGTEKPMNSIVVSGSASGSSGSNVGVVGGNGLGAVGSGIGGLAVGGGGGAGSSGGGGVGGNAASGVVGGSHVGLVGSNSGIGGVNSVPNSNAMMGVGGGLGSGSGSSGSGAGGEHLNDNSSNDKLVKSGVQTSPDGKVTNIPATMVNNQFGMVGLLTFIRAAETDPNLVTLSLGTDLTGLGLNLNSQESLHTTFAGPFVAQPCRAQDVEFNVPPEYLINFAIRDKLTAPVLKKLQEDLLFFLFYTNIGDMMQLMAAAELHSREWRYHVEEKIWITRIPGIDQYEKNG-TKERGTFYYFDAQSWKRLSKVFQIDPEKLD---KCPNISAFMNGQSV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06100-1", "uniprot_id": "NOT2_YEAST", "id": "P06100-1", "name": "General negative regulator of transcription subunit 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKFGLKALVP----------------------LLKLEDKELSSTYDHSMTLGADLSSMLYS----------------------------------LGIPRDSQDHRVLDTFQSPWAETS-----------------------------RSEVEPRFFTPESFTNIPG--------------VLQSTVTPPCFNSIQN-----------------------------------------------------DQQRVALFQDETLFFLFYKHPGTVIQELTYLELRKRNWRYHKTLKAWLTKDPMMEPIVSADGLSERGSYVFFDPQRWEKCQRDFLLFYNAIM---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V3I9-1", "uniprot_id": "Q9V3I9_DROME", "id": "Q9V3I9-1", "name": "NOT2/NOT3/NOT5 C-terminal domain-containing protein", "aln": "------------------------------------------------------MKRHYYNTGDDQQEVESSPSPPPPPPFQSPLSSPESLQTPDG----------YPILYVDVVKNKPKQELPPSASPSQPLAPEFSIFREDFPALPGSLPSALPT------------------ALPTTSSPVVPDDWTAMMSNSEQVELAKFRNTVIRNSSDPCVNANGNEVLRQPTHAPEKRQNMELLPHMYGYLGNPFR-------------------LNLSMIFTKQFLLEGVRQRAINAAHKRAALAKP-------------------------------AIQPPPGFENCKIFARLITNSDGMPLGG-----------------------VTFELGSPTNETTSNVEAKPSGSTIQGAFGMLGLAKKLRSINQNPLLFGNNVAHNIGG---------AADSIFTGPIQEARLTPQEMSYKLPLNYLFNVNMS--LQEPKIEEMHDELLFFFFYTYAGDMMQMLAAAELAERGWRYHKYEHFWVIRQADNPNYLYHG-FREFGEYNYFNMWQWKILPRHFYLDPEILERTLSKEELYVTYGYHPQMSGI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . . . :: . ::: * : : :: **:::* * ::* :: ** .* **** : *: : . . * * : :*: *. : * : : : ", "identical_positions": 19, "similar_positions": 39, "identity": "3.14%" }, { "cls_id": "homologset.agr.SGD:S000002325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y3D8-1", "uniprot_id": "KAD6_HUMAN", "id": "Q9Y3D8-1", "name": "Adenylate kinase isoenzyme 6", "aln": "------------MLLPNILLTGTPGVGKTTLGKELASKSG-LKYINVGDLAREEQLYDGYDEE--------------YDCPILDEDRVVDELDNQMREGG-----VIVDYHGCDFFPERWFHIVFVLRTD-----TNVLYERLETRGYNEKKLTDNIQCEIFQVLYEEATAS----------YKEEIVHQLPSNKPEELENNVDQILKWIEQWIKDHNS---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCP8-1", "uniprot_id": "KAD6_MOUSE", "id": "Q8VCP8-1", "name": "Adenylate kinase isoenzyme 6", "aln": "------------MKLPNILLTGTPGVGKTTLGKELASRSG-LKYVNVGDLAREGQLYDGYDEE--------------YGCPILDEDRVVDELEHQMQEGG-----VIVDYHGCDFFPERWFHIVFVLRTD-----NGVLYKRLETRGYNEKKLQDNIQCEIFQVLYEEAIAS----------YKEEIVHQLPSNEPEQLEDNINQISKWIEQWVKDHNP---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N034-1", "uniprot_id": "A0A8M1N034_DANRE", "id": "A0A8M1N034-1", "name": "Adenylate kinase isoenzyme 6", "aln": "---------MRIMKRPNILLTGTPGVGKTTLGKELAQRTG-LTYVNVGDLAQEAELFDGFDEE--------------YQCPILDEDRVVDELEDQMGDGG-----VIIDYHGCDFFPERWFHIVFVLRTD-----NTNLYNRLESRGYTGKKLQDNVQCEIFQTIFEEAVEA----------YKEEIVHQLPSNTPEDLERNLEQIVQWIEQWMKDNN----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JYV7-1", "uniprot_id": "KAD6_DROME", "id": "Q7JYV7-1", "name": "Adenylate kinase isoenzyme 6 homolog", "aln": "------MSEPEPDVKPNILITGTPGAGKSYLCERIASELK-FEWLDCSKIAKEKNFVEEYDEE--------------YDCPILDEEKLMDHLEPLMAKGG-----NVVEYHGCDFFPERWFQAVFVVTCP-----NTTLYDRLKERNYNEKKLASNIQCEIFGTILEEARDS----------YKSDIVFELKGETKADAHISIKTVKNWYRMWKRK------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12055-1", "uniprot_id": "KAD6_YEAST", "id": "Q12055-1", "name": "Adenylate kinase isoenzyme 6 homolog FAP7", "aln": "--------MEARRYGPNIIVTGTPGCGKSSTCEFLKNKLKDYKYYNISDFAKDNDCFEGYDEG--------------RKSHIVDEDKLLDMLEPLLRQGN-----SIVDWHVNDVFPERLIDLVVVLRCD-----NSNLYSRLHARGYHDSKIEENLDAEIMGVVKQDAVES----------YEPHIVVELQSDTKEDMVSNVSRIVAWEKMWLEQHPDG------------------VTNEYQGPRSDDEDDEDSE-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5BKE0-1", "uniprot_id": "TAF9_RAT", "id": "Q5BKE0-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPTVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATPAVQNVLINPSLIGSKNILITTNMVSQNTANESANALKRKREEEDDDDDDDDDDYDNL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: . * : : .. : : : . . . : . . * * . . : : . *:* . *: .: .. . : . :* :. :: .. .: . . ", "identical_positions": 7, "similar_positions": 44, "identity": "2.65%" }, { "cls_id": "homologset.agr.SGD:S000002326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AFS9-1", "uniprot_id": "TX13A_MOUSE", "id": "A2AFS9-1", "name": "Testis-expressed protein 13A", "aln": "-------------------------MALNPEDLGSGFRHS------------------KVSMFINEQMAKHDKGPDFYLENLSLSWEEVEDKFKVILEDSEVSN-------------EAREACAWGTLALGVR---------------FAHRQGCLQGHGVQWLQDLSSLHKMSALSLSPDLKQLIHQQEMAQKEVALQLQMAQAKLEEVQRERDLLRLKILQAELRALPNAVRP-----------------------------------------------------------------------AVAIPPAVVRRGGIRTQWSSTKENLAEWMAA--ATGRPNERAN-----------------------------------------MSDTALSGTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSPEEVLEDPNGSFMKLLGVMKCKNYPLKR-QRLDLRPKKASMCSFSQSLNLR--------------------------------------------------------------------------------------------------STVSSEPFIVQLPASFTYSYESPFP------AIPTTSQLPTTERQPHVYPYSMASDISHLSDMRIHRG---------------DHQELPKDKRFS--------AFRRPGDWDCPWCKAVNFSRRENCFHCGKGIWLQNP--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AHB6-1", "uniprot_id": "A0A8I6AHB6_RAT", "id": "A0A8I6AHB6-1", "name": "", "aln": "-------------------------MALNPEDLGSGFRHS------------------KVSMFINEQMAKHDKGPDFYLENLSLSWEEVEDKLKVILEDSEVPT-------------EAREACAWGTLALGVR---------------FAHRQGCLQGHGVQWLQDLSSLHKVAALSLSPELKHLTHSKEMEQKEGAIQLQMTQAKLEEVQRERDLLRLKILQAELRALPNTVRP-----------------------------------------------------------------------AVAIPPAVVRRAGTRTQWSNAKENLAELMAA--TTGKADERAN-----------------------------------------MTEAALEGTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTPEEASEEPNGNFMHLLGVVKWKNYPLKR-QRVDIKPKETSMCSLSQSLNLR--------------------------------------------------------------------------------------------------STASSEPFTVQLPASFTYSYESPFP------AIPTTSQLPTTERPPEMYPYSVASDMSHLSDMGIHRG---------------DHQELPKDKRFS--------AFRRPGDWDCPWCKAVNFSRRENCFHCGKGIWLQNP--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXU3-1", "uniprot_id": "TX13A_HUMAN", "id": "Q9BXU3-1", "name": "Testis-expressed protein 13A", "aln": "-------------------------MALRPEDPSSGFRHS------------------NVVAFINEKMARHTKGPEFYLENISLSWEKVEDKLRAILEDSEVPS-------------EVKEACTWGSLALGVR---------------FAHRQAQLQRHRVRWLHGFAKLHKSAAQALASDLKKLREQQETERKEAASRLRMAQTSLVEVQKERDK--------ELVSPHEWEQ-------------------------------------------------------------------------GAGWPGLATAGGVCTEGAAEEEEEAAVAAAGAAGGKGAEEEQR-----------------DVEVVAAPVEAMAPPVEAGAAPMETQFPHVEAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AASMETTEKLERILLQLLGDADQEKYTYWGQKEGDLRSVETATSYFSGTTNPW--------------------------------------------------------------------------------------------------SRASSEPLPVQLPASYSYSYSSPFSSFSDIPTISPPQATVTAPVPPQLPSDWEAFDTSLWSDGGPHRI---------------DHQEHPRDRRYSEPHQQRPPVYRRPGDWDCPWCNAVNFSRRDTCFDCGKGIWLQKPH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BXU2-1", "uniprot_id": "TX13B_HUMAN", "id": "Q9BXU2-1", "name": "Testis-expressed protein 13B", "aln": "-------------------------MALRPEDPSSGFRHG------------------NVVAFIIEKMARHTKGPEFYFENISLSWEEVEDKLRAILEDSEVPS-------------EVKEACTWGSLALGVR---------------FAHRQGQLQNRRVQWLQGFAKLHRSAALVLASNLTELKEQQEMECNEATFQLQLTETSLAEVQRERDMLRWKLFHAELAPPQGQGQ-------------------------------------------------------------------------ATVFPGLATAGGDWTEGAGEQEKE-AVAAAGAAGGKGEER------------------------------------------------YAEAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAPAEVLQGLGGGFRQPLGAIVAGKLHLCG-AEGERSQVSTN----SHVCLLW--------------------------------------------------------------------------------------------------AWVHSLTGASSCPAPYLIHILIPMP---FVRLLSHTQYTPFTSKGHRTGSNSDAFQL-----GGL----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YU32-1", "uniprot_id": "T13C1_MOUSE", "id": "D3YU32-1", "name": "Testis-expressed protein 13C-1", "aln": "-------------------------MAIEFGDHSSGFHHT------------------EVIRFINNEVLKNGGSSEFYTTFRSRSWNEIEDQLRTILVDPKVPR-------------SLKRACTWSALALSVR---------------VAARQRQQQARRVWRLQDQVGEHESASWTLVSELQRLREER----DQAAAQLLCTQIILQEAMDEREILRGRLLQAKRSALPVVPERGMEYG---------KTSLLSFEEKELGDLEFIGSQNMSHLEAQIPILSCLPGLSSPWVQAMDPFLQMTMAHPVPLKAKFSLEFSFSTPVPCPALMDSEATATAMITGLPQIAPSGIQPSSLCVTLESQETIASALDQICPRQKECSEILQDVSHLADSISCCEGEGPEKPQGTSLHGDSSNNSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNQAIPQIMAATEKKNLMMHQG------------------------------------------------------------------------------------------------------------------------------------------------------------TAAVEVNSNHSIKEEPVMPKGISSQGNKTSSTKKKRPKISRRVVGLIESISHNTQCVSVTPQETHTQVNKTTSTLKTYPGNLLRKPDQGKILSCNQKEDSKTLQRLT------------------------------------------DLGEGTRNCQKEDTFQQTTCLNAGVSPNEKKMPQGTGKNQSQRQKEEPNSFQANHPRKCKSYLMNKYPKIQLATKQRVKQPEGIKSLESKQPQETKSSESKQQEKPLSHRTSANCICPSSKTVNRSWYKGCYKCAKTSA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G6Y1-1", "uniprot_id": "A0A8I6G6Y1_RAT", "id": "A0A8I6G6Y1-1", "name": "", "aln": "-------------------------MALDTDDPKSGFRHS------------------EVVLFINEEVTRNGGGPGFYLTFRSRPWKDIEDGLKSVVIDTHVPR-------------SIKRACAWSALALGVR---------------VAVRQQEKQLRRVQQLHDQVEEHEAATWTLATDLQRLREER----DEVVSELLSAKNNLKQVVLERDMLQRKLVEFELSQQLLAESQDADY----------------------------------------------PGTP-----------------PRPLIVNKSRE--------------------ALDKGLQ-----------------------NGQNAVSPKAQMASLTVLDAFHGAEEFPASSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0J9YWL9-1", "uniprot_id": "TX13C_HUMAN", "id": "A0A0J9YWL9-1", "name": "Testis-expressed protein 13C", "aln": "-------------------------MAMNFGDHASGFRHD------------------DVIRFINNEVLRNGGSPAFYTAFRSRPWNEVEDRLRAIVADPRVPR-------------AIKRACTWSALALSVQ---------------VAARQQEELLYQVWWLQGHVEECQATSWALTSQLQQLRLEH----EEVATQLHLTQAALQQVLNERDGLCGRLLEVERSMQVYPMPQDFVPGPEAGQYGPVAGTLNAEQSEAVATEAQGMP-HSEAQVAAPTAVYYMPEPQSGRVQGMQPLLLMQAPHPVPFHMPSPMGLPYSTPLPPPVVM-ESAAAIAPQMPPAGIYPPG-----LWATVGSQEETAPPWDQKCHGQDGYPENFQGVYHPGDNRSCNQKEGSECPQGMTSQGDSSSHSLKKDPVMQEGTAPPEFSRSHSLEKKPVMPKEMVPLGDSNSHSLKKDPVVPKEIVPIGDSNSHSLTKNPVVHKEMVSLGDSNSHSMKKDPVMPQKMVPLGDSNSHSLKKDPMMCQEMVPLGDSNSHSLKKDPVVAQGTAPLMYSRRHSQKKVPMMPKEMVPLGESHSHSLKKDLVVPKELVPLGDSKSHRMKKDPVMPQKMVPLGDSR----SHSLKKDPVMPQNMIPLEDSNSHSLKKDPVMPQNMIPLEDSNSHSLKKDPMMHQEMVPLGDSNSHSLKKDPVVPQDTAPLMFSRRHSLKKVPVMPKEMVPLGDSHSLKKDPVMPQNMVPLEDSNSHSLKKDPVVPQGTAPLMFSRRHSLKKVPVMPKEMVPLGDSNSHSLKKDPVVPQGTAPLMFSRRHSLKKVPVMPKEMVPLGDSHSLKKD--PVMPQNMVPLEDSNSHSLKKDPVVPQGTAPLTFSRRHSLKKVPVVPQGTASLGFSRIHSLKKELVMPEEMVPLGDSNSHSMKKDLVMPKEMVPLGDSNSHSLKKDPVVHQEVVSLGDSNSHSLKKHPVIPQGTASLRFSKSHSQKEDQERPQVTPLEDSKSHGVKNSPWKHQPQG---QKVKEQKRKKASESQQQ-KPASCSSPVNWACPWCNAMNFPRNKVCSKCKRVRMPVENGSVDPA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0J9YY54-1", "uniprot_id": "TX13D_HUMAN", "id": "A0A0J9YY54-1", "name": "Testis-expressed protein 13D", "aln": "-------------------------MAMNFGDHASGFRHN------------------DVIRFINNEVLMDGSGPAFYVAFRSRPWNEVEDSLQAIVADSQVPR-------------AIKRACTWSALALSVR---------------VATRQREELLHHVRRLQRHAEERQATSWALTSQLQQLRLEH----EVAATQLHLAQAALQQALNERDGLYGRLLQIERFPQAAPLAHEIMSGPQAEQNGAAACPLATEQQSDMVAMGT----HANAQMPTPTDVLYVPGPLSPWAQGMQPP--LPVPHPFPHPPPFPMKFPSLPPLPPAVVTGAEAAAVPLQMPPTEIHPPC-----PWPAVGFQEEMAPLWYQRSYIQEEDSKILQGSFPLGDSRSHSQGEGSERSQRMPLPGDSGCHN---------------------------------PLSES-----------------------------------------------------PQGTAPLGSSGCHSQEEGTEGPQGMDPLGNRERQNQKEGPKRARRMHTLVFRRSHKSE-------------------------------------------GPEGPQGTVPQGDSR----SYSQE------------------------------------------------------GCSDR---------AQEMATLVFIRRCKP--------------------EGPKRPQWTVPLGDSRSHIKEEGPEGPQ---------------------RIVLQGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPERPQD-TPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPERPQDT-------------------------------------------PLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSRERAQGMATLVFSRSCKPEEGPERPQGTPLGDSRSHGVRESPKKWQPQR---QKAKKPKVNKVSGSQQQEKPASFPVPVNWKCPWCKAINFSWRTACYKCKKACVPFESGGQTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JGA3-1", "uniprot_id": "A0A0G2JGA3_MOUSE", "id": "A0A0G2JGA3-1", "name": "", "aln": "-------------------------MAMDWGDHSTGFRHS------------------EVIRFINNEILMNGGGPEFYLAFRMRPWNEIEDQLRAILIDPQVPR-------------SLKRACTWSALALGVR---------------IAARQREQQAYMVGLSQDAFGQLPSAPRASVSELWQLRQQR----EEAVTQLISTQAALQQAMRECDLLRRRLHHVERSVQMAPLVHDIQS----QQLGASVVPLSPDHARVMGTVGAYDRRYLEAQMSAATNVFYMPGSTSSWPLAMQPTVPVPVPYQLPAHPPFLTGSPFLMPFSPSVVVETEAGVVAP-VPLPPAYPSG-----PFAAPCSQN-PASVWDQRSYT--------------------YTTEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVTQRAVPAGNIR----DTSQE------------------------------------------------------GNSGK---------CQGTN----------------------------------------------------------------------------------TLGDNRSHLQEQDRQGVQYRATLVDTENDNEGENEELEATSAVAAEAASEEST-------------DTAEDEQEEEEEVAE---------------------------------------------------------------------KEEAYDNAVDLQNLQELHLPGQGQLHSQSDNRPQASGPASLYSGRCQIKEEDVEEAPPIPVWESWSQAVRESPKKQQPQLP--KKDKKPQAEAASESQPS-----SHSRMNWVCPRCKSMNFSWRKVCYKCKKICMPAEFGGQPH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32770-1", "uniprot_id": "DRI1_YEAST", "id": "P32770-1", "name": "Putative RNA-binding protein involved in heterochromatin assembly", "aln": "MHYVVLELQVAHLPDTPKDQCRIANIAFQIVNAETLVCHYGTNSLPSIEVNGTTKSLESAMVQLDKDIHDVIGNDDFVLVSLYSTWHIRVTLPRQARDDGFILTSYLQHPKVFDLWKEFDRWCVNHPEILGQKKAISNNNCNTKSISINAAKNTKDLDEIVRILEVSIPTEEAGSVPEIYSLLKRTTDILIQLHKKCTSPEDMESVLTKPYDSHTDIRAFLQEKSKILYMNNLPPDTTQSELESWFTQYGVRPVGFWTVKNIVEDTSNVNNNWSLNNSPYVEDQDSISGFVVFQTHEEATEVLALNGRSILSNLANTKQPRVVEHVLELQPSSTGVLDKAQEILSPFPQSKNKPRPGDWNCPSCGFSNFQRRTACFRCSFPAPSNSQIHTANSNNNVNSSRNNLNNRVNSGSSSNISNTAAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPYGAPEFNMIANNTPAALTYNRAHFP-------------------------------------------------------------------------------------------------------------------------------------------------------AITPLSRQNSLNMAPSNSGSPIIIADHFSGNNNIAPNYRYNNNINNNNNNINNMTNNRYNINNNINGNGNGNGNNSNNNNNHNNNHNNNHHNGSINSNSNTNNNNNNNNGNNSNNCNSNIG-----------------------------MGGCGSNMPFRAGDWKCSTCTYHNFAKNVVCLRCGGPKSISGDASETNHYIDSSTFGPASRTPSNNNISVNTNGGSNAGRTDGNDNKGRDISLMEFMSPPLSMATKSMKEGDGNGSSFNEFKSDKANVNFSNVGDNSAFGNGFNSSIRW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : : . * .. : :.: . * .*. : * : . *. . *. : * :: * . . .* . . . : * : . . . ", "identical_positions": 11, "similar_positions": 34, "identity": "1.01%" }, { "cls_id": "homologset.agr.SGD:S000002327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28332-1", "uniprot_id": "ADH6_HUMAN", "id": "P28332-1", "name": "Alcohol dehydrogenase 6", "aln": "------------MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTE---MKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFC-IQF----KQSKTQLMSDGTSRFT-CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQ-DLKK--PIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLP-ASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XI95-1", "uniprot_id": "ADH6_RAT", "id": "Q5XI95-1", "name": "Alcohol dehydrogenase 6", "aln": "------------MGTQGKVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTD---IKHLDTQELSKFCPMIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNIC-TEI----RLSKTHLASEGTSRIT-CKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFATGYGAAINSAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVDPR-DFEK--PIEEVLSDMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRSHLFFSGRILKGSILGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIRCVLLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1D5RMB0-1", "uniprot_id": "A0A1D5RMB0_MOUSE", "id": "A0A1D5RMB0-1", "name": "", "aln": "-----MEQASLATKTSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTD---NHTLEG-KMKTPFPVILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKEN----ILSPTGLMLDGTSRFT-CRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGSSCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPN-KLKK--PVQEVVKEMTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAP-TGSQLSFDPLVLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVLSMRP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZM50-1", "uniprot_id": "A0A8I5ZM50_RAT", "id": "A0A8I5ZM50-1", "name": "", "aln": "-----MERDSHTTKTSGDVITCRAAVAWTTNAPLSVEEVTVDPPKACEVRVKIISSGICGTD---NHILEG-KMETPFPVILGHEGAGIVESIGQGVTTVKPGDKVLMFPLPECRECIYCLHPKGNFCKKQN----ILSPTGLMLDGTSRFT-CRGKKIYHLQGTSTFTEYTVVDEIAVAKINDRAPMDTVCIISCEVSTGFGAVFNTAQVTPGSTCVVFGLGGIGSAIVMACKASGASRIIRVDTDEQKFPRARALGVTDCLNPK-KLEK--PVQKVVKEMTGVGVDFAFEAIGLIETMVSALKSCNRSSGVCVIMGVAP-TGSQLSFDPVLLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQK-FNIEPLITHRLPFPEINEGFKLLREGKCIRCVLSMRP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5Z6-1", "uniprot_id": "E9Q5Z6_MOUSE", "id": "E9Q5Z6-1", "name": "", "aln": "------------MNTLGKTITCRAAIAWAKNSPLSIEEVQVEPPKSGEVRIKMISSGICGSD---DHVLKG-ELVVNFPLIPGHEGAGIVESVGDGVCSMKPGDKVLILIIPQCRECDACLHPKGNFCYKQD----VLPCSGVMLDGTSRFS-CRGQKIYHSFRTSSFTEYTVVPEIAAVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEEKFPRARALGVTDCLNPN-KLEK--PVQEVVMEMTGVGVDFAFEAIGLVDTMVAAWNSCNNSYGVCLIAGLAP-SDAQLSLEAPKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTYQLPFNQLHEALELFHSGKAIRCVLLF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT84-1", "uniprot_id": "D3ZT84_RAT", "id": "D3ZT84-1", "name": "", "aln": "------------MDTLGKTITCRAAIAWAENSPLSIEEVQVEPPKSGEVRIKMISSGICGSD---DHMLKG-ELLANFPLIPGHEGAGIVESVGDGVCSVKPGDKVLTLIIPQCRECDSCLHLKGNFCEKQD----VLPCSGVMLDGTSRFS-CRGRKIYHSFRTSSFTEYTVVPEIAVVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEQKFPRARALGVTDCLNPK-KLEK--PVQEVVKEMTGVGVDFAFEAIGQVDTMAAAWNSCNHSYGVCLIVGLAP-SDTHLSLEASKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTHQLPFSQLHKALELYHSGKTIRCVLLF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64437-1", "uniprot_id": "ADH7_MOUSE", "id": "Q64437-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "------------MGTAGKVIKCKAAVLWGVNQPFSIEEIEVAPPKAKEVRVKILATGICRTD---DHIIKG-SMVSKFPVIVGHEAVGVVESVGEGVTTVRPGDKVIPLFLPQCRECNACLNPEGNLCIRSD-----LTGRGVLADGTTRFT-CKGKPVQHFMNTSTFTEYTVLDESSVAKVDGAAPPEKACLIGCGFSTGYGAAVKTAKVTPGSTCVVFGLGGVGLSVIMGCKAAGASRIIGIDINKDKFQKALAVGATECISPK-DSTK--PISEVLSDMTGNTIQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPP-SAKMLTYDPMLLFTGRTWKGCVFGGWKSRDDVPKLVTEFLEKKFDLDQLITHTLPFNNINEGFELLYSGKSIRTVLTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41682-1", "uniprot_id": "ADH7_RAT", "id": "P41682-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "------------MDTAGKVIKCKAAVLWGTNQPFSIEDIEVAPPKAKEVRVKILATGICGTD---DHVIKG-TMVSKFPVIVGHEAVGIVESVGEEVTTVRPGDKVIPLFLPQCRECNPCRNPEGNLCIRSD-----LTGRGVLADGTTRFT-CKGKPVQHFMNTSTFTEYTVLDESSVAKIDAEAPPEKACLIGCGFSTGYGAAVKTAKVSPGSTCAVFGLGGVGLSVVMGCKAAGASRIIGIDINKDKFQKALDVGATECINPR-DFTK--PISEVLSDMTGNTVQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPP-SAKMLSYDPMLLFTGRTWKGCVFGGWKSRDDVPKLVTEFLEKKFDLGQLITHTLPFHNISEGFELLYSGQSIRTVLTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40394-1", "uniprot_id": "ADH7_HUMAN", "id": "P40394-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTD---DHVIKG-TMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSD-----ITGRGVLADGTTRFT-CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK-DSTK--PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP-SAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00329-1", "uniprot_id": "ADH1_MOUSE", "id": "P00329-1", "name": "Alcohol dehydrogenase 1", "aln": "------------MSTAGKVIKCKAAVLWELHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSD---DHVVSG-TLVTPLPAVLGHEGAGIVESVGEGVTCVKPGDKVIPLFSPQCGECRICKHPESNFCSRSD----LLMPRGTLREGTSRFS-CKGKQIHNFISTSTFSQYTVVDDIAVAKIDGASPLDKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYSK--PIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHAACGVSVVVGVPP-NAQNLSMNPMLLLLGRTWKGAIFGGFKSKDSVPKLVADFMAKKFPLDPLITHVLPFEKINEAFDLLRSGKSIRTVLTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06757-1", "uniprot_id": "ADH1_RAT", "id": "P06757-1", "name": "Alcohol dehydrogenase 1", "aln": "------------MSTAGKVIKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSD---DHAVSG-SLFTPLPAVLGHEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKN---LTQPKGALLDGTSRFS-CRGKPIHHFISTSTFSQYTVVDDIAVAKIDAAAPLDKVCLIGCGFSTGYGSAVQVAKVTPGSTCAVFGLGGVGLSVVIGCKTAGAAKIIAVDINKDKFAKAKELGATDCINPQ-DYTK--PIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHSACGVSVIVGVPP-SAQSLSVNPMSLLLGRTWKGAIFGGFKSKDAVPKLVADFMAKKFPLEPLITHVLPFEKINEAFDLLRAGKSIRTVLTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00325-1", "uniprot_id": "ADH1B_HUMAN", "id": "P00325-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH1B", "aln": "------------MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTD---DHVVSG-NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKND----LGNPRGTLQDGTRRFT-CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00326-1", "uniprot_id": "ADH1G_HUMAN", "id": "P00326-1", "name": "Alcohol dehydrogenase 1C", "aln": "------------MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD---EHVVSG-NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKND----LGNPRGTLQDGTRRFT-CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07327-1", "uniprot_id": "ADH1A_HUMAN", "id": "P07327-1", "name": "Alcohol dehydrogenase 1A", "aln": "------------MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTD---DHVVSG-TMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKND----VSNPQGTLQDGTSRFT-CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28474-1", "uniprot_id": "ADHX_MOUSE", "id": "P28474-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANQVIRCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKILATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKSVFHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAAVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGASECISPQ-DFSK--SIQEVLVEMTDGGVDYSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEE-ISTRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINQAFDLMHSGDSIRTVLKM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12711-1", "uniprot_id": "ADHX_RAT", "id": "P12711-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANQVIRCKAAVAWEAGKPLSIEEIEVAPPQAHEVRIKIIATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKPILHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAAVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGATECINPQ-DFSK--SIQEVLIEMTDGGVDFSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEE-ISTRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINKAFDLMHSGNSIRTVLKM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11766-1", "uniprot_id": "ADHX_HUMAN", "id": "P11766-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQ-DFSK--PIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEE-IATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32771-1", "uniprot_id": "FADH_YEAST", "id": "P32771-1", "name": "S-(hydroxymethyl)glutathione dehydrogenase", "aln": "----------MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIEYTAVCHTD---AYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECGKCKFCTSGKTNLCGAVR----ATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDCTGNTKIMRDALEACHKGWGQSIIIGVAAAGEE-ISTRPFQLVTGRVWKGSAFGGIKGRSEMGGLIKDYQKGALKVEEFITHRRPFKEINQAFEDLHNGDCLRTVLKSDEIK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P46415-1", "uniprot_id": "ADHX_DROME", "id": "P46415-1", "name": "Alcohol dehydrogenase class-3", "aln": "-----------MSATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTD---AFTLSGADPEGLFPVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIR----LTQGAGVMPEGTSRLS-CKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPK-DVADKGSIQNYLIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQE-ISTRPFQLVVGRVWKGSAFGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QAY7-1", "uniprot_id": "A0A8M9QAY7_DANRE", "id": "A0A8M9QAY7-1", "name": "Alcohol dehydrogenase 6", "aln": "---------MVAMETEGKVIKCKAAVAWEPGKPLSIEKVEVAPPKAHEVRIKIAASGVCHSDWAYLYDIAKMKPR-PFPLVLGHEGAGVVESVGPGVTKVSIGDKVIPLFLPQCGQCERCQSPKTNLCTKNW----EKTQQGVLADGTSRIT-CKNQQVHQFIGISTFSEYTVVPEDNVTKIHPDAPLDRVCLLGCGVSTGYGAAVNTGKVESGSTCAVFGLGAVGLAAVMGCKAAGASRIIAVDINSDKFEIGKTFGATEFVNPK-DHSK--SIQEVLRELTNGGVDYALECVGDVAVMRAAVEACSPAGGVCVIVGWIEV-EE-LSLAPLDILLGRTLKGTYFGGWKSVEAVPRLVQDYLSRKILLDEFVTHRLALDQINQAFDLIMSGKSIRTVIEM----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QYY9-1", "uniprot_id": "ADH4_MOUSE", "id": "Q9QYY9-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTD---INATDPKKK-ALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFT-CKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINTAKVTPSSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCLNPR-ELDK--PVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDK---MTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLMKEGKSIRTILTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64563-1", "uniprot_id": "ADH4_RAT", "id": "Q64563-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTQGKVITCKAAIAWKTDSPLCIEEIEVSPPKAHEVRIKVIATCVCPTD---INATNPKKK-ALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKKCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFT-SKERSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFTSGYGAAINTAKVTPGSACAVFGLGCVGLSAVIGCKIAGASRIIAIDINSEKFPKAKALGATDCLNPR-DLDK--PVQDVITELTGGGVDFSLDCAGTAQTLKAAVDCTVVGWGSCTVVGAKVDE---MNISTVDMILGRSVKGTFFGGWKSVDSVPNLVTDYKNKKFDLDLLVTHALPFDKINDAIDLMNQGKSIRTILTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08319-1", "uniprot_id": "ADH4_HUMAN", "id": "P08319-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTD---ATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFT-CKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR-DLHK--PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG-LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * * *:: : *: :*.: * .*:: ***::: :* :: * : *** .*:***:* * . ** *: : . * .* * * * : * *: . . : : .:* :***: : . :. : : .*::.* ..:*:*:..: .:: .. .*:* * :* : ..* ** :* :* : .: .* :: :.*. . . .: . : :: . : :: * : : . * . * : .. *: :. *. : . : :: :: : : ::* : . ... *. ", "identical_positions": 57, "similar_positions": 117, "identity": "14.11%" }, { "cls_id": "homologset.agr.SGD:S000002330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89000-1", "uniprot_id": "DPYD_RAT", "id": "O89000-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVLSRDAPDIESILALNPRIQAHATLRSTMAKKLDKKHWKRNTDKNCFICEKLENNFDDIKHTTLGERGALREAVR---------------------------------------------------------------CLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNP----------LGLTCGMVCPTSDLCVGGCNLHATEEG------------PINIGGLQQFATEVFKAMNIPQIRSPLLPPPEHMP----------------EAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVG------GLSTSEIPQFRLP---------------------YDVVNFEIELMKDLGVK------------------------IICGKSISTD-----------------------------EMTLSTLKENGYKAAFIGIGLPEPKKDHIFQGLTQVQ---------------------GFYTSKDFLPLVAKGSKPGMCACHSPLPSVRGAVIVLGAGDTAFDCATSALRCG-------ARRVFIVFRKGFANIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVGMQFVRTEQDETGNWVE-------------------DEEQIVRLKADVVISPFGSVLDDPKVIEALSPIKFN------------------------RWGLPEVNPETMQTSEPWVFAGGDVVGMANTTVESVNDGKQASWYIHEYIQAQYGALVPS-QPTLPLFYTPVDLVDISVEMAGLRFPNPFG----------------------------LASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTT----------SGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDN-----------------------ILIASIMCSYNKNDWMELS------KMAEASGADALELNLSCPHG------MGERGMGLACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVSIARAAKEG-----------GADGVTATNTVSGLMG------------------LKADGSPWPSVGSG---------KRTTYGGVSGTTIRPIALRAVTAIARALPGFP-----------------ILATGGIDSAESGLQFLHSGASVLQVCSAIQ------------------NQDFTVIEDYCTGLKALLYLKSIEELSDWDG-----QSPPTMSHQKGKPVPHIAELMGQKLPS-------------------------------------FGPYLERRKKILAASKIR------ENDQNRACSPLQRKHFNSQKPIPAIKDVIGKSLQYLGTFGELNIMEQVVALID-----------EEMCINCGKCYMTCNDSGYQAIQFDP---------------ETHLPTVSDTCTGCTLCLSVCP--------------------IMDCIRMVSRATPYEPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHR6-1", "uniprot_id": "DPYD_MOUSE", "id": "Q8CHR6-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVLSRDAPDIESILALNPRVQAHATLRSTAAKKLDKKHWKRNTDKNCFTCEKLESNFDDIKHTTLGERGALREAVR---------------------------------------------------------------CLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNP----------LGLTCGMVCPTSDLCVGGCNLHAAEEG------------PINIGGLQQFATEVFKAMNIPQIRNPSLPPPEHMP----------------EAYSAKIALFGAGPASISCASFLARLG---------------------------------YSNITIFEKQEYVG------GLSTSEIPQFRLP---------------------YDVVNFEIELMKDLGVK------------------------IICGKSLSTD-----------------------------EMTLSSLKENGYRAAFIGIGLPEPKKDHIFQGLTQVQ---------------------GFYTSKDFLPLVAKSSKTGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCG-------ALRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVAMQFVRTEQDETGNWVE-------------------DEEQTVRLKADVVISAFGSVLEDPKVKEALSPIKFN------------------------RWGLPEVNPETMQTSEPWVFAGGDVVGMANTTVESVNDGKQASWYIHKHIQAQYGTSVPS-QPTMPLFYTPVDLVDISVEMAGLRFPNPFG----------------------------LASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTT----------SGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDN-----------------------ILIASIMCSYNKSDWMELS------KMAEASGADALELNLSCPHG------MGERGMGLACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVSIARAAKEG-----------GADGVTATNTVSGLMG------------------LKADGTPWPAVGIG---------RRTTYGGVSGTAIRPIALRAVTAIARALPGFP-----------------ILATGGIDSAESGLQFLHSGASVLQVCSAIQ------------------NQDFTVIEDYCTGLKALLYLKSIEELADWDG-----QSPPIISHQKGKPVPRVAELMGQKLPS-------------------------------------FGPYLEQRKKIIAASKIR------QKDQNTACSPLQRKHFNSQKPIPAIKDVIGKSLQYLGTFGEMSIMEQVVALID-----------EEMCINCGKCYMTCNDSGYQAIQFDP---------------ETHLPTVSDTCTGCTLCLSVCP--------------------IMDCIRMVSRATPYQPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12882-1", "uniprot_id": "DPYD_HUMAN", "id": "Q12882-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMR---------------------------------------------------------------CLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNP----------LGLTCGMVCPTSDLCVGGCNLYATEEG------------PINIGGLQQFATEVFKAMSIPQIRNPSLPPPEKMS----------------EAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVG------GLSTSEIPQFRLP---------------------YDVVNFEIELMKDLGVK------------------------IICGKSLSVN-----------------------------EMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQDQ---------------------GFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCG-------ARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKGGRIVAMQFVRTEQDETGKWNE-------------------DEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFN------------------------RWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSA-KPELPLFYTPIDLVDISVEMAGLKFINPFG----------------------------LASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTT----------SGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDN-----------------------IVIASIMCSYNKNDWTELA------KKSEDSGADALELNLSCPHG------MGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEG-----------GANGVTATNTVSGLMG------------------LKSDGTPWPAVGIA---------KRTTYGGVSGTAIRPIALRAVTSIARALPGFP-----------------ILATGGIDSAESGLQFLHSGASVLQVCSAIQ------------------NQDFTVIEDYCTGLKALLYLKSIEELQDWDG-----QSPATVSHQKGKPVPRIAELMDKKLPS-------------------------------------FGPYLEQRKKIIAENKIR------LKEQNVAFSPLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMID-----------EEMCINCGKCYMTCNDSGYQAIQFDP---------------ETHLPTITDTCTGCTLCLSVCP--------------------IVDCIKMVSRTTPYEPKRGVPLSVNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYG8-1", "uniprot_id": "DPYD_DANRE", "id": "Q6NYG8-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATMLSKELQDIESILALNPRVKSHANVHSTASKKNEKKHWKRNPERSCDSCVNLENNFDDIKHTTLSERGALREALR---------------------------------------------------------------CLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNP----------LGLTCGMVCPTSDLCVGGCNLYASEEG------------PINIGGLQQFATEVFSKMGIPQIRNPELPTADNMP----------------KSFHTRIALIGCGPASISCASFLARLG---------------------------------YDNITIFEKQKYIG------GLSTSEIPQFRLP---------------------YEVVQFEIDLMKDLGVK------------------------VVLEKGLGQN-----------------------------GLTLTSLKEEGYQVVYIGIGLPQANRDKIFEGLTTEQ---------------------GFYTSKDFLPLVAKASKIGMCNCRSQLPKLHGNVIVLGAGDTAFDCATSALRCG-------ARRVFVVFRKGFTNIRAVPEEMEAAKEEKCEFLP-----------FLSPHEVIKKNGRVSGLRFCRTEQQDDGTWIV-------------------DEEQIVHLKADFIISAFGSMLNDPAVTKALDPIKLN------------------------RWGTPEVNSETMQTTEPWVFAGGDIAGFANTTVESVNDGKQASWHIHKYIQSLHGNTISA-TPRLPLFHCSIDTVDISVEMCGIKFPNPFG----------------------------LASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVRGTT----------SGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKN-----------------------IIIASIMCSYNQADWTELA------KMAQESQADALELNLSCPHG------MGERGMGLACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVDIATAAYEG-----------GADGVTATNTVSGLMA------------------LKADATPWPGIGRG---------ARTTYGGVSGNAIRPIALRAVSAIARALPGFP-----------------ILATGGIDSAESGLQFLHAGASVLQVCSAVQ------------------NQDFTVIEDYCLGLKALLYLKSIEELHDWDG-----QSPPTIRHQKGKPVPHVSELIGKSLPS-------------------------------------FGPYLQTKTQALAKYKKD------ASG-DVIMDTGAARVNIPKKPIPNVKDVIARALKHIGAYQELDNTEQVQALVD-----------PEMCINCGKCYMTCNDSGYQAIKFDP---------------ETHLPVITDSCTGCTLCLSVCP--------------------IIDCIKMVSRTTPYEPKRGLP--VNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12680-1", "uniprot_id": "GLT1_YEAST", "id": "Q12680-1", "name": "Glutamate synthase [NADH]", "aln": "--------------------MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWAN--------------VIPDKRGLYDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSD-GNGDGAGILLGIPHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLSVLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEASLQIGLEN-WFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTFPSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDSAALDNVLELLTINGTLSLPEAVMMMVPEAYHKD--MDSDLKAWYDWAACLMEPWDGPALLTFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLFLVDTQLGEMVDTKKLKSQISKRQDFKSWLS-KVIKLDDLLSK-TANLVPKEFISQDSLSLKVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQLFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALKNIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGAN-RVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLAMETLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGAQIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPESGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELDFENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGEDAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAHKVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVGVGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRRNVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQDPYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAINIDLSPILTPAHVIRPGVPTK-FTKKQDHKLHTRLDNKLIDEAEVTLDRGLP-VNIDASIINTDRALGSTLSYRVSKKFGEDGLPK-DTVVVNIEGSAGQSFGAFLASGITFILNGDANDYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNSGATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKINKDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKKVLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNKATLKEPKVVDLEDAVPDSKQLEKNSER-IEKTRGFMIHKRRHETHRDPRTRVNDWKEFTN-PITKKDAKYQTARCMDCGTPFCLS-DTGCPLSNIIPKFNELLFKNQWKLALDKLLETNNFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFTVGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLLSAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLLESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPPVERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVRVEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATLDDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQRDYKLLKELASQV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9NFH8-1", "uniprot_id": "M9NFH8_DROME", "id": "M9NFH8-1", "name": "Glutamate synthase [NADH]", "aln": "MAPTITDNCEFECATVEATTTSAITIGDSDNFDSSAIGGSGDNFEESNELHLNGQQDQDVQEEQQQQMPWEAPGKQGLYDPQNEHEACGVGFIVAIDGKRSHKILRDAQTLSERMNHRGACACDNDTGDGAGVLASIPHGLYSKALAKQG-VTLPELGDYATG-IFYLDEAQH-----AAAEKEFDDLAKSLGLEVIAWRTVPSNQSAIGVVARKSE-----PLSRQVFVRRPAGSDEKAFERQVFVLRKRASHELIKPGRRFYICSLSDRTVVYKGLFTSDQLWDYYTDLKDPEFETYLALVHTRFSTNTFPSWERAHPLRVLAHNGEINTLRGNVNLMKAREGVMQSDLFGDQLKKLYPVVEPNLSDSGSFDCVLEFLTMASDRSLPESVMTMVPEAWQNDKTMPQEKRDFYQWAACVMEPWDGPALISFTDGRYIGAVLDRNGLRPSRFYVTKENVLVMASEVGVYDVDPSQVTLKSRLKPGRMLLVDTKEKKLIQDIELKAKIAKSRPHSEWLQQKMITLDEIRNANVLNTPPVDELAKLPASERGIFDPRLSLFGYSTETVNMLLIPMFKNKKEALGSMGNDAPLACLSNFQPIPYEYFKQLFAQVTNPPIDPFREKVVMSMQCPLGPEANLLQPSAQQVHRIWLTNPILSIPDTQLLK--RNTHRGWRTKVLDITFQYNEGVQGYIDAIDRICREGYAAAQAGYQLLVISDRGAGIDGKVAVSALLALGALHHHLIETLQRMKVGIVVETAEAREVHHICVLLGYGADAICPYLAFELAQALRDDGVIAPEVNDK------QIYAAYAQAIDTGIAKVMAKMGISTLQSYKSAQIFEAVGLGSDLVAKCFRGTQSRIGGVTLEILAKEGLQRYQLTYG--KATPDTRILRNPGQYHWRHGGEAHINEPSSIGSLQEAAVNKNLDAFEAFKKTTLDSVKKCALRGQLEFVTD-RQSIDISEVEPASEIVKRFATGAMSFGSISLEAHQTLSITMNRIGGKSNTGEGGEDSDRYLNQDPNNSRRSAIKQVASGRFGVTASYLANADDLQIKMAQGAKPGEGGELPGYKVTKDIAKTRKSVPGVGLISPPPHHDIYSIEDLAELIYDLKCSNPNARISVKLVSEVGVGVVASGVAKGKAEHIVISGHDGGTGASSWTGIKNAGLPWELGVAETHQVLVLNNLRSRVIVQADGQLRTGFDVVVAALLGADEFGFSTAPLIVMGCTMMRKCHLNTCPVGIATQDPELRKKFTGKPEHVINFFFMLAEDIRKIMAGLGIRKFQDLIGRTDLLRVASQRDAKASNLDLKLLLQPALELRPGTNIVGGSVKQDFQLEKRSDNELIAKAQQIFSGADDNVTVKMRIHNEERAFGSTLSYHIACKYGEAGLPAGKSIDIFLEGSAGQSFCAFLARGVNVTLKGDANDYVGKGLCGGNVVIMPQDTVPFESHLNVIVGNVCLYGATEGTAYFRGIASERFCVRNSGVTAVVEGV-GDHGCEYMTGG-VVVILGLTGRNFAAGMSGGIAYVYDLDG-SFKPKVNPESVELLPLEIEKDVLLVKELLADFIEKTGSKVAKELLDNWAEAQGKFVKVFPYEYQKALKD----------------------------------MAEQQAVEQPLKSAIENGNGK--HEPHIKDIEEAIQDVVLEQKRADRVLDKTRGFVKYKRESAPYRDAGERQKDWDEVYNFPHVRKNLKVQAARCMECGVPFCQSNSTGCPLGNIIPKWNDLVFHGEWQEALRQLLQTNNFPEFTGRVCPAPCEGSCVLGISEPAVTIKNIECAIIDHAFEQGWIKPEIPEVRTGKRVAIVGSGPSGLAASQQLNRAGHFVTVFERNDRVGGLLQYGIPTMKLSKEVVKRRVDLMADEGIEFRTNVHVGKDLKAEQLLQEYDAVLLTTGSTWPRDLPLANRDLKGIHFAMEFLEAQQKKQLGGKNDIISA--AGKNVIIIGGGDTGCDCIATSLRQGAKSITTFEILPEPPQKRAQDNPWPQWPKVFRVDYGHEEVKLKWGKDPRQYCTTTKEFVG-ENGAIKGVNTVEVEWTKTETGQWRMQEVAGSEKYFPADLILLAMGFLGPEKTVPSELGLELDPRGNIKASN-GQYGTSNSKVFAAGDCRRGQSLVVWAITEGRQAARQVDSYLTGRPSGLPGPGGVIATS-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.. ::: : : .. *.* ..: . : ...*.:.. * * : .. .: : :: ::* ..: .:.: : . * .. * * * :: . . : :::. : . . : :. .: . . : * . . *. :* : ::. : :* :.: :: * : . ::* : . *: :: : . : : :* : . :* * :: . * : :* *:. * .: *. . . : * * : .. : :: .. : : .: : * :.. : . : :. : : : : .:**: :. :: ::. * . :* . : .: :: ..:: .:. :.*: .. : : : * .: . *: : .:: ** . ::. *.:. * : * : : ::.:: .:: : . : *. . : . ** . : ..:. : : .**. . :: : . *.* :::*. * : ** :* . . : . : . * * *:. .:: : *:.*.. : . * : . . : .: ..: : : * . : . . : .* .: : :. * : . : . : : : : : . . . * .. : * . . : .. : : : ..: : :..: . :: . : *::** : . .:* :: * * . . . :* : * *:* . .* *. * : ", "identical_positions": 76, "similar_positions": 318, "identity": "3.47%" }, { "cls_id": "homologset.agr.SGD:S000002333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNG8-1", "uniprot_id": "LDHD_MOUSE", "id": "Q7TNG8-1", "name": "D-lactate dehydrogenase, mitochondrial", "aln": "-------MAMLLRVATQRLSPWRSFCSR-GSQGG-----------------------------------------------------------------------LSQDFVEALKAVVGSPHVSTASAVREQHGHDESMHRCQPPD------AVVWPQNVDQVSRVASLCYNQGVPIIPFGTGTGVEGGVCAVQGGVCINLTH---MDQITELNTEDFSVVVEPGVTRKALNTHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHY-----------------------RKSAAGYNLTGLFVGSEGTLGIITSTTLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARIEFLDDVMMDACNR---HSKLNCPVAPTLFLEFHG-SQQTLAEQLQRTEAITQDNGGSHFSWAKEAEKRNELWAARHNAWYAALALSPG----SKAYSTDVCVPISRLPEILVETKEEIKASKLTGAIVGHVGDGNFHCILLVDPDDAEEQRRVKAFAENLGRRALALGGTCTGEHGIGLGKRQLLQEEVGPVGVETMRQLKNTLDPRGLMNPGKVL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1W9-1", "uniprot_id": "A0A0G2K1W9_RAT", "id": "A0A0G2K1W9-1", "name": "D-lactate dehydrogenase, mitochondrial", "aln": "-------RAMLLRVATQRLSPWRGYCSR-GSQGG-----------------------------------------------------------------------LSQDFVEALKAVVGSPHVSTASAVRQHHGHDESMHRCRPPD------AVVWPQNVDQVSRLASLCYNQGVPIIPFGTGTGVEGGVCAVQGGVCISLTH---MDQIMELNTEDFSVVVEPGVTRKALNTHLRNSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHY-----------------------RKSAAGYNLTGLFVGSEGTLGIITSATLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARIEFLDEVMMDACNR---HSKLNCPVAPTLFLEFHG-SQQALAEQLQRTEAITQDNGGSHFSWAKEAEKRNELWAARHNAWYAALALRPG----SKAYSTDVCVPISRLPEILVETKEELKASKLTGVIVGHVGDGNFHCILLVNPDDVEEQRRVKAFAENLGRRALALHGTCTGEHGIGLGKRQLLQEEVGPVGVETMRQLKDTLDPRGLMNPGKVL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WU2-1", "uniprot_id": "LDHD_HUMAN", "id": "Q86WU2-1", "name": "D-lactate dehydrogenase, mitochondrial", "aln": "-------MARLLRSATWELFPWRGYCSQ-KAKGE-----------------------------------------------------------------------LCRDFVEALKAVVGGSHVSTAAVVREQHGRDESVHRCEPPD------AVVWPQNVEQVSRLAALCYRQGVPIIPFGTGTGLEGGVCAVQGGVCVNLTH---MDRILELNQEDFSVVVEPGVTRKALNAHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYSPCVSLGRRKSAAGYNLTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHILQAAVPVARIEFLDEVMMDACNR---YSKLNCLVAPTLFLEFHG-SQQALEEQLQRTEEIVQQNGASDFSWAKEAEERSRLWTARHNAWYAALATRPG----CKGYSTDVCVPISRLPEIVVQTKEDLNASGLTGSIVGHVGDGNFHCILLVNPDDAEELGRVKAFAEQLGRRALALHGTCTGEHGIGMGKRQLLQEEVGAVGVETMRQLKAVLDPQGLMNPGKVL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QXM5-1", "uniprot_id": "LDHD_DANRE", "id": "F1QXM5-1", "name": "D-lactate dehydrogenase, mitochondrial", "aln": "----MTLFRHLVRITSPRLPFICGSSRRFSAKTA-----------------------------------------------------------------------AVERVVSSFRSVTGDEGVSVGSAVREQHGRDESVHRCRPPD------VVVFPRSVEEVSALAKICHHYRLPIIPFGTGTGLEGGVGALQGGVCFSLRK---MEQVVDLHQEDFDVTVEPGVTRKSLNSYLRDTGLWFPVDPGADASLCGMAATSASGTNAVRYGTMRENVLNLEVVLADGTILHTAGKGRRP-----------------------RKTAAGYNLTNLFVGSEGTLGIITKATLRLYGVPESMVSAVCSFPSVQSAVDSTVQILQAGVPIARIEFLDDVMINACNR---FNNLSYAVTPTLFLEFHG-SSKSMEEQVSVTEEITRDNGGSDFAWAEDEETRSRLWKARHDAWYAAMALRPG----CKAYSTDVCVPISRLPQIIVETKADLISNNITGPIAGHVGDGNFHCLIVLDPNDTDEVQRVHSFTERLARRALAMDGTCTGEHGIGLGKRALLREEVGPLAIEVMKGLKASLDPRNLMNPGKVLELTQTNTEQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32891-1", "uniprot_id": "DLD1_YEAST", "id": "P32891-1", "name": "D-lactate dehydrogenase [cytochrome] 1, mitochondrial", "aln": "MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWLKYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLHDPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTTEEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDLDITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENIINMTIVLPDGTIVKTKKR--------------------------PRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVAVVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFKIGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSKDKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNFHAFIVYR--TPEEHETCSQLVDRMVKRALNAEGTCTGEHGVGIGKREYLLEELGEAPVDLMRKIKLAIDPKRIMNPDKIFKTDPNEPANDYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : .*. :: * *. . . . : ..:.:: .. . *. :::*:..::** : :*: :*::**. **.:** . . : * ..: *:.: .:. *:.:.*:.*:. : ** :* : ** * ***..*.: * *...***** *****::*::*: :**.** :::* : **::*****..**********::* :*:: : *:: . *. :* ::: *. .: :: *:.: : :*:**: *:. * .. . **:*::: * * : : :. .: :.: * . * :*:: : : .** **: * ::.: . .* ::***.**:*:: ::: :** :: :. : . *.**.******.::: :* :.:.: :*** ********:*:*** * **:* :: *: :* :**: :***.*:: ", "identical_positions": 137, "similar_positions": 187, "identity": "22.28%" }, { "cls_id": "homologset.agr.SGD:S000002334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC15-1", "uniprot_id": "ZCHC7_RAT", "id": "B1WC15-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGFETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYSQNIHNANEEEGYEE----KNCESSETVSIQPDQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAQEKTQSPATPRSNK--VANKCKRSNKKPEPEESPSTIREVMIIEVSSDEEEES---TISENENVESWMLLGCEED-------------------------------------------------DKDNDILLNLVGCKDAGAEGENDVN----WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRPCCLCSERGHLQYGCP-ARYCLDCSLPMSSTHRCFERSSWRKR--CDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMFNQAFPTSPFIYCYDDKYDIQ------------QRDRRIKRKLKDIKKNGDFP-----------------RQFKRPHGEETD-RYHHDRRK---------SRFSGKRSRWPRE-----------SKETQKE-KTRGREGEKHR-----RDRQ---PRDEDEDFPRGLKPNSS-SSSNS------QKPSKSLHQASHYHRLREEKLRRE--SMRSKPKKR-KFVEDGSHDDLFLIKQRKKKPKSSGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AX39-1", "uniprot_id": "ZCHC7_MOUSE", "id": "B1AX39-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGYETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYAQSIHNANKEEGYEE----KNCENSETVSSQPNQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAEEKTQSPATSHSNK--VAQKCKRNNKKPKPEERPGVIREVMIIEVSSNEEEES---TTSENENVESWMLLGSEED-------------------------------------------------GKDNDILLNLVGCETAGA--EDDVN----WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRACCLCSERGHLQYGCP-ARYCLDCSLPMSSNHRCFERLSWRKR--CDRCDMIGHHADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMFNQTFPTSPFIYCYDGKYDIQ------------QRDRRIKRKVKDLKKNGDFP-----------------RQFKRPHVEETDKRRHHDMRK---------SRSPRKYRRWPRE-----------NKETQKE-KTRSREGKTHR-----RGHQ---PRGEDEDFPRGSKPNAS-GCANN------QKPSKSLHHASHYHRLREERLLRE--SKRSKPKKR-KSTEDGSHDDLFLIKQKKKKPKPSGL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3Z6-1", "uniprot_id": "ZCHC7_HUMAN", "id": "Q8N3Z6-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFGGYETIEAYEDDLYRD--ESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEE----KNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEES---TISEGDNVESWMLLGCEVD-------------------------------------------------DKDDDILLNLVGCENSVTEGEDGIN----WSISDKDIEAQIANN---------------------------------------------------RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCP-APLCEYCPVPKMLDHSCLFRHSWDKQ--CDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPS-PVSPFICYYDDKYEIQ------------EREKRLKQKIKVLKKNGVIP-----------------EPSKLPYIKAANENPHHDIRK---------GRASWKSNRWPQE-----------NKETQKEMKNKNRNWEKHR-----KADR---HREVDEDFPRGPKTYSSPGSFKT------QKPSKPFHRSSHYHTSREDKSPKE--GKRGKQKKKERCWEDDDNDNLFLIKQRKKKS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5M8-1", "uniprot_id": "A0A8M3B5M8_DANRE", "id": "A0A8M3B5M8-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSPLSNHVCVAPYFCAQAVEITLSLLGFLPRALLEMFSGLQERYDHEDELYRDEEDSSGLSDSDSELEFRLYSQLHYNAEFQENHEESSKVQPLVPQTQLQPETMPPAPPVDVIVIDSGPDSFTVSDST-----EDDESVCANKVQSLKHCKRKSQPSRFRSPSPPQVQAGRSSPDDVVVLDSDLEQSSSESEPPFVEDLDSDTD---SDSDSDGLENWMILGKGRQ-------------------------------------------------DGDQSIQLNLAQSSFVNTEYVNYRGQEQKWTVSEKDKQAQIYNKGHGP-----------------------------------------------RHVPNRSTYRYYTEKSITCRNCNKTGHLSKNCPTLKKVPCCSLCGLRGHLLRTCP-NRHCSNCSLPGHTSDDCLERAFWYKR--CHRCGMTGHFIDACPQIWRQYHLTTTAGPIRKSADPKACQKRAYCYNCSRKGHFGHQCSQRRMYNWSYPSLPVITYYDTVNDIK------------CRDFRLKKKAREMQDAGLISPDGGVVTFTPQPPRKKQKVSHSPHPYSNNTNNHHTPKKRIAHTPKHNPQTNQQNTHWRVKQNSKKPGPHGKNTPQSKEFKSQNKEAKNKK-----RKKKKAAVIDEDADFPRGSKKSPHKAGFHSSTQKANVKPVKLFGVEKNHMKKKDKSKKKERIQRKRQQKAAKDSAAYPTDENLFQIKQRKVKRSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12476-1", "uniprot_id": "AIR2_YEAST", "id": "Q12476-1", "name": "Protein AIR2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKNTAPFVVDTAPTTPPDKLVAPSIEEVNSNPNELR---ALRGQG-----RYFGVSDD-------------------------------------------------DKD------------------------------------------------------------------------------------------------------AIKEAAPKCNNCSQRGHLKKDCP---HIICSYCGATDDHYSRHCPKAIQCSKCDEVGHYRSQCPHK-WKKVQ--CTLCKSKKHSKERCPSIWRAYILVDDN---EKAKPKVLPFHTIYCYNCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELK------------QEYYRHMNRNSDENEDYQFS-----------------ESIYDEDPLPRPSHKRHSQND---------HSHSGRNKRRASN--------------FHPPPYQKSNVIQPTI-----RGET----LSLNNNISKNSRYQNTKVNVSS-------ISENMYGSRYNPSTYVDNNSISN-------------SSNYRNYNSYQPYRSGTLGKRR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VVA9-1", "uniprot_id": "Q9VVA9_DROME", "id": "Q9VVA9-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "MSDLEEMDSERLNELESILYASIHYSDGFEEHTAMDQPAKESTSDQDARSMPPPPQQKHPIPGQRFVSGTRVINNSMQKPRYWIDGAAAVGEGQVVQAEEQQATTNKTMPAVEESSSSQSMDVDMPQDKSLLLSPEKGTSNQPKTASQPPKHQQIPQAKQQQNIHAKQLQNQQAKPQEQKNSQQKQQQSLKQQNQQSKQHQNQQKKSAPVVQKPKPQPNASTKVNHEAYEAERFDQRLLVAIPPNCPPKKQNKPQQNKQQQQQNKQQQKKQQQSLQHNKQQQQSGPGPFGKANRKLEQIQRLADKKQKSKQAQLNKKQRKQQSPPVEFVNLAETSESSDDDDVVHVPLPPAPIIELDTSDGEQTCTSSQLFHEENAMDATDVKMGLSCITEPEGTSVVASSTTPPMHSPSCSVMSSDDFIVQKDTTRLLTECENANDEDLLVLTETAIREAIGEEPKDKEVVENASEEQEHDHAADTSSEYEFVPPSRLEEIKKNYRVDDQQFRALDVYESESDLTESGIYSKAKSKTTPTIIRNVDSSSGSSSVEEVVEPSVQKTKRLRKRSCSTNNHSQSDPNNDDGLDDSDSDDGVHATGVPGIARGMAVERCKRKIRRISTRHSSDDNSKKAATRIQKPKVAAVHHASSESASEDELPSARDIAERLLNQQQGQGKVQVQKGDGDDDAISIGSDEDSHAEAEFRDAMTDRLAAVFERLDAKAKKMEEDEEQVNASGYISDEEDSRDKSADTTVRSDEDIDASNDLEETNPDKNDRDVTNEEQHVHVEHNLQELRDESLPKSGDLIGWNEEMRSFYNDSWNGENFSVHKVQRMMTGHRHEWRINTADRCPVARPRSHAKCSNCFEMGHVRSKCPRPRKPLVCFICGTMGHAEPRCP-NAICFGCGSKQEIYVQQCNKCSFHSRLVCQLCKMRGHGVDHCPDKWRRYHSTTRSNTELDSRVQYRSVQCSYCAGRHSFENCRQRIGDFRSTNYTSQIVSHQKIYKNRGGPIGNLGDLKSFFAIETPFHFKWNNPSMPKNCYYSRFLVNANLAKVQSVKRKSTTAVSQIPEKIYTHEYVPNAQVKAAR---GEVSTGTAKKPLTKQMPVVESIAENRTAEEPIGKLNREDEKSKDILPLPEVPPEVKQTQDEKLVEGQPNQSQPDEELPMKDDDQEEPSSSVQREEITTNFDNPPTEPGLSRTPLAPHELDSDSNYSFSEHFELPSSTTSDGQPNTQLPLVRTMGTLPDVIPLSKDDFELSSNVQGISMCVNSSSTSLRTDETPDPDSSEELPDVPSEGKIIMAREESEYLFSAEGRTFLAAAAKQCHVSVRMDFKDYGYVLVIYGLKKHQEELQVKLLRRSQEVKRKSIEFQSQKPPKRIDVLIRFLRDGINSLNTNLGNAKSHYVRIKELEGMNTKNGFKMAEKKRRQLNMILVGQAGLLNGKTHLDQLLVLLRRLIDDFSPDEHATPQLRNEIEEHWRMIFSSYPHPNYDSLLNSYGRLDQKNRLPSLHIDPVLLGLQQKKTQSQPQSPSKGPPSPTPLPPVRQDMAPPPPPKMSKKKQRQALDQQTQNQQRQQQQQQQRLQQQHQNQQQRLQQQQKQQQQSLQQQHQQQRVQQQRMQQQQQHQQQDNNQYQQNLRRPQIDQMPYNNLQQRSRSDLQLRHTLNPECDRLLSEMDHNQPGSINKDANKPSMFWSRESLKYLDDLFKMTSNTETVERLKRVLQRSQRGLLSHNDYRAVIRLHSLMCN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :* : . . . * ** : **: ..** : . . .* ** * * : : * * * : *.. ** * . .. ** : . : . . . . : . . . .: . : .. : : .: .. . . : : . . ", "identical_positions": 22, "similar_positions": 52, "identity": "1.27%" }, { "cls_id": "homologset.agr.SGD:S000002337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIM3-1", "uniprot_id": "D2HDH_MOUSE", "id": "Q8CIM3-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MVLPLVSRWSARVLWASPGWRRTYTQRACVGLKRLGCPRGVYSPLAHRAYSVVAGGPEVTLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVIT---DPEQLQTCNVDWLKTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVNVAFLGCPGFAEVLQTFRTCRGMLGEILSAFEFMDTECMQLVGQHLQLTN-PVQ-ESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVTDGTMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRL------GPRAKHVVG---YGHLGDGNLHLNVTAEAFSRELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKDVLGYSKPPVAVTLMQQLKAMLDPEGILNPYKTLPAQA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84850-1", "uniprot_id": "D2HDH_RAT", "id": "P84850-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MVLHLVPRWSASLFRASPRWKKTYSQRASAQLKWLGCPRSVYSPLACRAYSKVSGSPEVMLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVIT---DPEQLQTCNVDWLRTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVNVAFLGCPGFTEVLQTFRTCKGQLGEILSAFEFMDAECMQLVGQHLHLTN-PVQ-ESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVIDGTMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRL------GPRAKHVVG---YGHLGDGNLHLNVTAEAFSQELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKNVLGYSKPPVAVKLMQQLKAMLDPKGILNPYKTLPARA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N465-1", "uniprot_id": "D2HDH_HUMAN", "id": "Q8N465-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "MLPRRPLAWPAWLLRGAPGAAGSWGR--------------PVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVT---DPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLHLAS-PVQ-ESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARL------GPHAKHVVG---YGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L258-1", "uniprot_id": "D2HDH_DANRE", "id": "A1L258-1", "name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "aln": "--MGLFQKCSRLSLRSSYMWSVCPQYSIAVTARETPDRALIVHWTQHRDVHNSRRLGANPANPSAAPP-RLPFSRVTQEDLSFFRALLPGRTIT---DPDLLKSSNVDWLKTVQGSSDVLLRPKTTEGVSQILRYCNERNLAVCPQGGNTGLVGGSVPVFDEIILSTSLMNQVFAFDNISGILTCQAGCVLENLSHYLEERDFIMPLDLGAKGSCHIGGNVSTNAGGLRLLRYGSLRGTVLGLEVVLADGHVLNCLATLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPRKPKAVNVAFLGCSSFQQLLETFQCCRGMLGEILSAFEFLDASCMNLLEKHLKLTN-PIT-ECPFYIVIETAGSNATHDEEKLHQFLEEVMTSSLVTDGTVATEATKIKALWSLRERVTEALTHEGYTYKYDISLPVEKIYDLVQDMRRHL------GGMAKNVVG---YGHVGDGNLHLNITSPSKDFDLLAAIEPYVYEWTSQWKGSISAEHGLGLKKRNYIYYSKPSEAVALMGSIKAMLDPKGILNPYKTLPDNIN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46681-1", "uniprot_id": "DLD2_YEAST", "id": "P46681-1", "name": "D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2", "aln": "MLRNILVRSTGSNFKFAGRYMKSSAL---------------LGYYRRVNYYSTKIQTRLTSENYPDVHRDPRFKKLTSDDLNYFKSILSEQEILRASESEDLSFYNEDWMRKYKGQSKLVLRPKSVEKVSLILNYCNDEKIAVVPQGGNTGLVGGSVPIFDELILSLANLNKIRDFDPVSGILKCDAGVILENANNYVMEQNYMFPLDLGAKGSCHVGGVVATNAGGLRLLRYGSLHGSVLGLEVVMPNGQIVNSMHSMRKDNTGYDLKQLFIGSEGTIGIITGVSILTVPKPKAFNVSYLSVESFEDVQKVFVRARQELSEILSAFEFMDAKSQVLAKSQLKDAAFPLEDEHPFYILIETSGSNKDHDDSKLETFLENVMEEGIVTDGVVAQDETELQNLWKWREMIPEASQANGGVYKYDVSLPLKDLYSLVEATNARLSEAELVGDSPKPVVGAIGYGHVGDGNLHLNVAVREYNKNIEKTLEPFVYEFVSSKHGSVSAEHGLGFQKKNYIGYSKSPEEVKMMKDLKVHYDPNGILNPYKYI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *. ::.:** *. ::. : :.: *. * **::. :* *.::***:: * ** **.:* ..::** *******:******:***:*** : :*:: *. :**** *:** :**: ..*: *:::::***********:** *:*******:******:*:*******:.:* :::.: ::***********:*******:*:** ***: :*:*.**::*. .* :: :.* .: *.********:*: . * :*: : *: * ***:::**:**. ** .** .**..: ..:* **.:* : ::: ** ** :.** :* .:***:***:: :*.:* . :* * .* *** ***:********:: . .: ::**.** :.: :**:*****:*::*:: : ***.. : :* .:*. **:******* : ", "identical_positions": 210, "similar_positions": 154, "identity": "38.18%" }, { "cls_id": "homologset.agr.SGD:S000002338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7B2-1", "uniprot_id": "CNPD1_RAT", "id": "Q6P7B2-1", "name": "Protein CNPPD1", "aln": "MDLAGLLLDEEGTFSLSGFQDFTFLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPD--YLQHVSSSDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVPTLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPMWQLSLGSLCQRLVKLSCLLAVAYVSSVALAVASMAVIHQSLGLSSSPSPSPPELTLVPKNLLQPCIPAPVPQCLT---NVSSCLEDSVELPSLWGSLLDPLTPPLMPPPDPPAPPTPFHKCPFCQKFQRNPPNCRACHQPNRTVSIGPIHPFYHTHGLAPPWLWSPVAPPFLQPQQCSLFSVMKLARLTSVIFPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K158-1", "uniprot_id": "CNPD1_MOUSE", "id": "Q8K158-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGAFSLTGFQDFMVLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPD--YLQHVSSSDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVATLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSSSPSPGPPELTLVSKSLVQPCVPAPVSQCLT---NVSSCLEGSVDLPSLWGSLLAPLTPPLRPPPDPPAPPTPLHKCPLCQKFQRLPPNCRACHT-NQTVSIGPSRPLYHARGLAPPWLWSPVAPPFLQPQQCSLFSVMELAHLKSVISPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV87-1", "uniprot_id": "CNPD1_HUMAN", "id": "Q9BV87-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGTFSLAGFQDFTFLPGHQKLSARIRRRLYYGWDWEADCSLEELSSPVADIAVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPD--YLQHVSSSDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVPTLNALERGFLSAMDWHLYTDPREIFEVLSWLESCVAEQQGRWRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSCIPTPGPPDLGLTSRCLLEPCIPS-VPQCLPSLANVSSCLEGSMGLRSLWGSLLASLTPPPLPPPDPPAPPTLLHNCHLCQKLQRDSPTCHACLHPNRTVPTALSSPWYHTYGLAPPWPWSPVLLSLPQPQQCSLFSVMELARLKSFVFPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12477-1", "uniprot_id": "PCL9_YEAST", "id": "Q12477-1", "name": "PHO85 cyclin-9", "aln": "-----------------MISDYDALLQFNKKPVSQEMIQFLATSTASIIKIRENNNPIQGCRPPDLS------------IFIKNVVIQSNVQTPTLMATSVYLNKLKSVIPKNVYGINTTRHRIFLGCLILAAKTLNDSSP----WNKHWTTYTEGLLRIREVNTIERELLEYLNWDVRITTPDLIDSLSYFLGPIKEQLFLQR----RQEMLLFNAPSPGQLKEYINHRRPVSHSRTSSAISVP----SLTSMATVSTTDSRSSLLAKYQPSLPLVESDNFN--------------------KKNHVPLR---------------------------NNNDICNNFRAEEN-------------IHSVNHIDVTMGSSPVMSHKPTIHQRLNFTRRGWSSFFKQ----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: * .:* .. . : . . : .:.* ..*: . *. :: :* :: :.. ::* : **:::*: *. * :.: :** .:::*:* * *.. :*..* : * : : :*::** :*. ::* : . :::: **:: . : ** * :: :: . ** :* *. * :. *. :::*:*.: : . *. : *.* *. .: :. : * :: :*:::: : * :* .*. : : . *.:: ", "identical_positions": 50, "similar_positions": 114, "identity": "12.05%" }, { "cls_id": "homologset.agr.SGD:S000002341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38060-1", "uniprot_id": "HMGCL_MOUSE", "id": "P38060-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "MASVRKAFPRRLVGLTSLRAVS---------------------------------------------TSSMGTLPKQVKIVEVGPRDGLQNEKSIVPTPVKIRLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSVFGAVSELFTRKNANCSIEESFQRFAGVMQAAQAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVMHEVPVTALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLNGLGIHTGVNLQKLLEAGDFICQALN--------------------------------------------------RKTSSKVAQATCKL-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97519-1", "uniprot_id": "HMGCL_RAT", "id": "P97519-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "MATVRKAFPQRLVGLASLRAAS---------------------------------------------TSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALN--------------------------------------------------RKTSSKVAQATCKL-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35914-1", "uniprot_id": "HMGCL_HUMAN", "id": "P35914-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "MAAMRKALPRRLVGLASLRAVS---------------------------------------------TSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLG---GCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALN--------------------------------------------------RKTSSKVAQATCKL-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZS7-1", "uniprot_id": "HMGC2_MOUSE", "id": "Q8JZS7-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "MGNLPSAAKHCLNYQQLLREHLWSGDSVAGALDAAQ------------------------------EASQLPGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMRGIRQYPGVRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFQEVISSARHMDIPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGMGLNTGVDLYKVMEAGEFICKAVN--------------------------------------------------KTTNSKVAQASFNARLE--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5C3-1", "uniprot_id": "HMGC2_RAT", "id": "D4A5C3-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQ------------------------------EASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVN--------------------------------------------------KTTNSKVAQASFKARLE--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB92-1", "uniprot_id": "HMGC2_HUMAN", "id": "Q8TB92-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQTSLLTNLHCFQPDVSGFSVSLAGTVACIHWETSQLSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLG---GCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVN--------------------------------------------------KTTNSKVAQASFNA-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WG57-1", "uniprot_id": "HMGC2_DANRE", "id": "A8WG57-1", "name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "aln": "MGNVSSAVKHCLSYETFLRDYPWLPRLLWEEK-----------------------------------CSELPKLPVYVKIVEVGPRDGLQNEKEIVPTEVKIQLIDLLSQTGLPVIEATSFVSSKWVAQMADHTAVLKGIKRSPDVRYPVLTPNIQGFQAAVAAGANEVAVFGSASETFSRKNINCSIEESLQRFEQVVSAAKQEGIPVRGYVSCALGCPYEGQVKPSQVTKVAKRLFELGCYEVSLGDTIGVGTAGSMAEMLSDVLTEVPAGALAVHCHDTYGQALPNILIALQMGVSVVDASVAGLG---GCPFAKGASGNVSTEDLLYMLHGLGIETGVDLLKVMEAGDFICKALN--------------------------------------------------RKTNSKVSQATRNN-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM58-1", "uniprot_id": "Q9VM58_DROME", "id": "Q9VM58-1", "name": "hydroxymethylglutaryl-CoA lyase", "aln": "---MISAPIRSILALTAKR-------------------------------------------------TAVTSAANQVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLG---GCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELG--------------------------------------------------RTSESKVNRAWKGPQARVK------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48570-1", "uniprot_id": "HOSC_YEAST", "id": "P48570-1", "name": "Homocitrate synthase, cytosolic isozyme", "aln": "---MTAAKPNPYAAK----------------------------------------------------PGDYLSNVNNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLG----LKAKILTHIRCHMDDAKVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIR------FSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIR-TLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVKSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKARVDQLNLNLTDDQIKEVTAKIKKLGDVRSLNIDDVDSIIKNFHAEVSTPQVLSAKKNKKNDSDVPELATIPAAKRTKPSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .:::: *:* * :. : **.: *.: *: ** ** *:.. : : : . : ::.. . *: :*. : :. ..*. : . . ::. .: .: * ... . : :: : . :* .:.:.**:* ... : :: . : : * *: * *:.* :*: * ::* :* *:* * . * .. . *: :.. :: ::: . : .. . .::* : ", "identical_positions": 36, "similar_positions": 104, "identity": "7.29%" }, { "cls_id": "homologset.agr.SGD:S000002344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXR0-1", "uniprot_id": "A0ABK0LXR0_RAT", "id": "A0ABK0LXR0-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------IRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIK-HKIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEGVKEKLSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50516-1", "uniprot_id": "VATA_MOUSE", "id": "P50516-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------IRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIK-HKIMLPPRNRGSVTYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38606-1", "uniprot_id": "VATA_HUMAN", "id": "P38606-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------ILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIK-HKIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSDYAQLLEDMQNAFRSLED-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCD8-1", "uniprot_id": "E7FCD8_DANRE", "id": "E7FCD8-1", "name": "H(+)-transporting two-sector ATPase", "aln": "-----------------------------------------------------------------------------------------MDFSKLAK---------------------------------IRDEEREGQFGYVHGVSGPVVTASSMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINDLTQSIYIPRGVNIGALNRDLKWEFTPSKNLRVGSHITGGDIYGNVFENSLIK-HKIMLPPKSRGTVTYVAPPGNYDVSDVVLELEFEGVKEKFTMMQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVGGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYTRALDEYYDKHFPEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGVLSNMIAFYDMARHAVETTAQSDNKITWAMIREHMGEILYRISSMKFKDPVKEGEEKIKADYAQLLEDMQNAFRTLED-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27331-1", "uniprot_id": "VATA2_DROME", "id": "Q27331-1", "name": "V-type proton ATPase catalytic subunit A isoform 2", "aln": "-------------------------------------------------------------------------------------------MSNLKR---------------------------------FDDEERESKYGRVFAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINELTESIYIPKGVNVPSLSRVASWEFNPLN-VKVGSHITGGDLYGLVHENTLVK-HKMIVNPRAKGTVRYIAPSGNYKVDDVVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFYDKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSYSSYDRFCPFYKTVGMLRNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMKFKDPVKDGEAKIKADFEQLHEDLQQAFRNLED-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48602-1", "uniprot_id": "VATA1_DROME", "id": "P48602-1", "name": "V-type proton ATPase catalytic subunit A isoform 1", "aln": "-------------------------------------------------------------------------------------------MSNLRK---------------------------------FKDEERESEYGRVYAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLRDIGVMTNSIYIPKGVNTTALSRSEMWEFNPLN-VRVGSHITGGDLYGVVHENTLVK-QRMIVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHPLFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTCEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDEYYDKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQNSYSPYDRVCPFYKTVGMLRNIMAFYETARHAVESTAQSDNKITWNTIRESMGGIMYQLSSMKFKDPVKDGEQKIKADYDQLYEDLQQAFRNLED-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK47-1", "uniprot_id": "Q9VK47_DROME", "id": "Q9VK47-1", "name": "H(+)-transporting two-sector ATPase", "aln": "MEKKSWVAPLTSFTNSNASNEDRARNSGSLNQDGEPRSVPHPTVPAKKCTCPTCACQRNDHKSNPVPPPPQSRKPVAEPESPHDTVNDEDSLKDLRRSTDQSHKSAHIALEKNEDSGFVIEQVVDTHKYSSDEEEEEATMGRIFGVSGPVVNAEEMAGAAMYELVRVGHSQLVGEIIRLEGDMATIQVYEDTSGVSVGDPVYQTGKPLSVELGPGIMGSIFDGIQRPLRSISELTNSIYVPKGIDTPSLPRNIAYEFTPGK-LKIDALITGGDIYGSVFENSMMHDHRLILPPRTKGRIRWLAPPGNYCVDEVIVETEFNDEITKHTMLQVWPVRRCRPVEDKLPSNSPLLTGQRVLDAFFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPQLEVEVNGTMESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADAGYPAYLGARLASFYERAGLVKCLGSPDREGSVSIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLQSYSKYMRTLDTYYEESNPEFTHLRAKAKKVLQEEDDLAEIVQLVGKSSLNEEDKITLEVAKMLKDDFLQQNSYSQYDAYCPFFKTIGMLKNMMTFYDAAILSVQNTADNEARVTWGLIRIKAANILYELSTMKFIDP-KLGEATVLESMNKLHDNILSTFREIEDNVEDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17255-1", "uniprot_id": "VATA_YEAST", "id": "P17255-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------MAGAIENARKEIKR--------------------------------ISLEDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGK-FQVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSDAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGAN------WSKLADSTGDVKHAVSSSKFFEP-SRGEKEVHGEFEKLLSTMQERFAESTD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : ::. *. * :..****** * * *.******:**: :****:**::** *******:*:*::***** :************:* :*:******* * ::***:*:*:: :* * ::* * : .::. *:***:** * **::: ::::: *: :* : ::**.*:* .: ::* **:. . :: :.**** *** :**.:: **:*******::*********.**************:********.***** ********:*** :**:* *:.* *.*****:***********************:***** * :*:*:***:**************.***** *:******:**:****** . .**.*:* ******.****.*********:***.*.******************:* ***** ..*: :*:. .** ** : *::*.: ::* ::******::* : **:**:**.::*:******.*: ** **::**..:: :: ::: * :* . *: * : . : : :*: ** :* . ** : . :* . : . * * ", "identical_positions": 334, "similar_positions": 159, "identity": "27.86%" }, { "cls_id": "homologset.agr.SGD:S000002347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63330-1", "uniprot_id": "PP2AA_MOUSE", "id": "P63330-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63331-1", "uniprot_id": "PP2AA_RAT", "id": "P63331-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYA4-1", "uniprot_id": "A0A0G2JYA4_RAT", "id": "A0A0G2JYA4-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPTIDTLDHIGALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67775-1", "uniprot_id": "PP2AA_HUMAN", "id": "P67775-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKVFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFZ9-1", "uniprot_id": "A0A8M1PFZ9_DANRE", "id": "A0A8M1PFZ9-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MEEKAFAK----------ELDQWIEQLNECKQLSETQVKTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62715-1", "uniprot_id": "PP2AB_MOUSE", "id": "P62715-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62714-1", "uniprot_id": "PP2AB_HUMAN", "id": "P62714-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62716-1", "uniprot_id": "PP2AB_RAT", "id": "P62716-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23696-1", "uniprot_id": "PP2A_DROME", "id": "P23696-1", "name": "Serine/threonine-protein phosphatase PP2A", "aln": "----------------------------------------------------------MEDKATTK----------DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23595-1", "uniprot_id": "PP2A2_YEAST", "id": "P23595-1", "name": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit", "aln": "MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :* :****:*:*.:*: *.* :* **. * ::* *.**: :. ***:***********:***:*** .**********************: ***:**** .*:***************************.***** *******:*:*****.:********** *:::*:: *:*:*******************************:******** **::*.*:*::**********.*.*::********************:**:*:. : .***:**: * *** ***:******", "identical_positions": 224, "similar_positions": 59, "identity": "59.42%" }, { "cls_id": "homologset.agr.SGD:S000002348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TM6-1", "uniprot_id": "R3HD2_MOUSE", "id": "Q80TM6-1", "name": "R3H domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEDVEKEGEENGLRQETQRRTSSHGHARKRAKSNSKLKLVR---------------SLAVCEESS-TPFVDGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSR---------------------------------------------------------------------------------------------------------------------------------------------------------------DSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILDFINDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSSTRIPEQR-FSEHIKDEKNTEFQQRFILKRDDA---------SMDRDDNQMRVPLQDGRRSKSIEEREE-------------------------------------------------------------------------------------------------------------------------------------EYQRVRERIFAR--ETGQNGYLNDIRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSS----TDSELKSLEPRPWSSTDSDG----------SVRSMRPPVTKASSFSGISILTRGD---------------SIGSSK----------------GGSAGRLSR-----PGMALG-----APEVCNQVTSPQSV--------RGLLPCTAQQQQQQQQQQQQLPALPPTP-QHQPPLNNHMISQPVPALQPSPQPVQFSPSSCPQVLLPVSPPQQ-----YNMAEDLSNPFGQMSLSRQGSTEAADP----------SSALFQPPLISQHPQQASFIMASAG---------------QPLPTSN-------YSTSSHAPPTQQVLPPQGYM-QPPQQIQVSYYP---------------------------PGQYPNSNQQYRPLSHPVAYSPQRGQQLPQASQQPGLQPMMSNQQQTAYQGMLG----------------------------------------VQQPQNQGLLSNQRS-SMGGQMQGLVVQYTPLPSYQVPVGSDSQNVVQPSFQQPMLVPASQSVQGGLPTGG------VPVYYSMIP----PAQQNGTSPSVGFLQPPGSEQYQMPQSPSP-----------------CSPPQMS-QQYSGVS--PSGPGVVVMQLNVPNGPQAPQNPSMVQ--------WSHCKYYSVEQRGQKPGDLYSPDGSPQAN--------------------------------------AQMGSSPVTSPTQSPAPSPVTSLSNVCTG--------------------LSPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP---------GAGGGDNS------------------------------------GTAENGRHPDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLX2-1", "uniprot_id": "A0A8I5ZLX2_RAT", "id": "A0A8I5ZLX2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEEVEKEGEENGLRQETQRRTSSHGHARKRAKSNSKLKLVR---------------SLAVCEECS-TPFVDGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKDDKDKSKEKVPRKMLSR---------------------------------------------------------------------------------------------------------------------------------------------------------------DSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILDFISDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSSTRIPEQR-FSEHIKDEKNTEFQQRFILKRDDA---------SMDREEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QAGQNGYLNDIRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSS----TDSELKSLEPRPWSSTDSDG----------SVRSMRPPVTKASSFSGISILTRGD---------------SIGSSK----------------GGSAGRLSR-----PGMTLG-----APEVCNQVTSPQSV--------RGLLPCTVQQQQQQQQQQQQLPALPPVP-QQQPPLNNHMISQPVPALQPSPQPVQFSPSSCPQVLLPVSPPQQ-----YNMAEDLSNPFGQMSLSRQGSTEAADP----------SSALFQSPLISQHPQQASFIMASAG---------------QPLPTSN-------YSTSSHAPPTQQVLPPQGYM-QPPQQIQVSYYP---------------------------PGQYPNSNQQYRPLSHPVAYSPQRGQQLPQASQQPGLQPMMSSQQQTAYQGMLG----------------------------------------VQQPQNQGLLSNQRSNSMGGQMQGLVVQYTPLPSYQVPVGSESQNVVQPPFQQPMLVPASQSVQGGLPAGG------VPVYYSVIP----PAQQNGTSPSVGFLQPPGSEQYQMPQSPAP-----------------CSPPQIP-QQYSGVS--PSGPGVVVMQLNVPNGPQAPQNPSMVQ--------WGHCKYYSVDQRGQKPGDLYSPDGDPQTN--------------------------------------AQMGSSPVTSPTQSPAPSPVTSLSSVCTG--------------------LSPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP---------GAGGGDNS------------------------------------GTAENGRHADLAALYTIVAVFPSPLAAHNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K5-1", "uniprot_id": "R3HD2_HUMAN", "id": "Q9Y2K5-1", "name": "R3H domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEEIEKECEDTSLRQETQRRTSNHGHARKRAKSNSKLKLVR---------------SLAVCEESS-TPFADGPLETQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKNKEKIPRKMLSR---------------------------------------------------------------------------------------------------------------------------------------------------------------DSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFINDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSNTRIPEQR-FSEHIKDEKNTEFQQRFILKRDDA---------SMDRDDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QTGQNGYLNDIRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSS----TDSELKSLEPRPWSSTDSDG----------SVRSMRPPVTKASSFSGISILTRGD---------------SIGSSK----------------GGSAGRISR-----PGMALG-----APEVCNQVTSSQSV--------RGLLPCTAQQQQQQQQQQ--LPALPPTP-QQQPPLNNHMISQ---------------------------------------ADDLSNPFGQMSLSRQGSTEAADP----------SAALFQTPLISQHPQQTSFIMASTG---------------QPLPTSN-------YSTSSHAPPTQQVLPPQGYM-QPPQQIQVSYYP---------------------------PGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIG----------------------------------------VQQPQNQGLLSSQRS-SMGGQMQGLVVQYTPLPSYQVPVGSDSQNVVQPPFQQPMLVPVSQSVQGGLPAAG------VPVYYSMIP----PAQQNGTSPSVGFLQPPGSEQYQMPQSPSP-----------------CSPPQMP-QQYSGVS--PSGPGVVVMQLNVPNGPQPPQNPSMVQ--------WSHCKYYSMDQRGQKPGDLYSPDSSPQAN--------------------------------------TQMSSSPVTSPTQSPAPSPVTSLSSVCTG--------------------LSPLPVLTQFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP---------GGGGGDNS------------------------------------GTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GEX2-1", "uniprot_id": "A0A8I6GEX2_RAT", "id": "A0A8I6GEX2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MRMSDIVIIKDETETMKDLEAEMRDTTRVENLIKSENYGKISAEKNEHCIDNNIDLQRPPQSFGQTGKRSKSSSKLKLVR---------------SLAVCEESPPPPAAEIPQETQEKIQIQLTQSFEKEE-KPSKDETDKE---KASDKLPRKMLSR---------------------------------------------------------------------------------------------------------------------------------------------------------------DSSQEYTDSTGIDLHEFLVNTLKNNPRDRMMLLKLEQEILDFIGNNESPRK-KFPPMTSYHRMLLHRVAAYFGLDHNVD-QSGKSVIVNKTSNTRIPDQK-FNEHIKDDRGEDFQKRYILKRDNS---------SFDKDDSQMRIRLKDDRRSKSIEEREE-------------------------------------------------------------------------------------------------------------------------------------EYQRARDRIFSQDSLCSQENYIIDKRIPDEDTIG-TQQRRQIFRVNKDASGRSTNSHQSS----TENELKYSEPRPWSSTDSDS----------SLRNLKPAVTKASSFSGISVLTRGD---------------SSGSSKSIGRLSKTGSESSGSVGSSTGSLSHTQQPLPGSALSQSSHGAPVIYPAASNHSSLSFDGGLNGQGASPSTSFLLLPLEATGIPPGSILINP-QTGQPFINPDGSPVVYNPPMTQQSVRTQVPGPPQPPLPPPPPQQPAASHMFSQDNLGSQFSHMSLARQPSADGSDP----------HATMFQSTVVLQSPQQSGYIVTTAPPHPP------PPPPPPPPPPSLPPGQSVPTASFSGHPVSQPVLQQQGFLPQPSPQMPACYCA---------------------------PGHYHSSQPQYRPIPS-VHHSSHLNQPLPQPAQHTGYQ-VMPNQQQ-NYQGIVG----------------------------------------VQSPQSQSLMGGQPN-STGPHIQGVVIPYPSVPSYQVSLPQGSQGIAHQTYQQPVVFPN-QSNQGSLPTAG------MPVYYSVIP----PGQQSNLSSAVGYLQHPGSEQVQFPRTTSP-----------------CSSQQLQGHQCAALPQQPPGGGMVMMQLNLPNN-APSRAHSPPQ--------WKQNKYHCDHQRGQKCMEVSHMDSIVQHS--------------------------------------PQLSS-PILSPVQSPAPAQLSALKTTRPS--------------------GPPLSIVSQFARPFVPGQGDARYPLLGQPLQYSP---PTLLHGHIPH--QQGQSGSRHGNRGRRQAKKAASTDLGAGEAVVGKVLEITELPDGITRMEAEKLFGELFKIGAKIRWLRDPQSQPQ--LRRHPLCCGSGDNT------------------------------------VNPERSKPSDLASTYTVLATFPSISAAQSALKKQIHSVNKFKLRMSKKHYDFHILERASSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MSX1-1", "uniprot_id": "ENC_DROME", "id": "Q8MSX1-1", "name": "Protein encore", "aln": "MSSTKSQVALATNIPTNLSSAASASTAAAAAAVVVVASANAAVASSANSSGVGSGSGPGPGSGAGVSGPVAAGTATAVATGSTVTAATSVAATTSTSVATISTSCSSSSINNINNNCGEECQSAAGSSNLGRQNSFGNRRGNMKGKHLTRSHAMRESTSPPRTPTPRAASEQQQQQLQGEQHEHNNNNNINSSSKAQSAGRGNSPLMETPAVIVTSQQPQQQQQQQQQQQQSVPPKPQQNVPLSNEAEFPKLSPPKKSGGQHNRTNSNGSGMEFNNNNNSSNKKFVVDMKANGLDNKPHNNSSTGVIFNSGMNYKAAERHDRHERHEMSSQNSNLSNNHDEEPYHYEPRGGGGGKKHRANTNAKGNKPRLKNLGGSSSGSIDLGGGGGNGNCNNMSNNGQSNNSSNNTSGFISRENSSEQYTDYGGTDLLVFFRDTLNKNPKDRNILLKIEKDLIDFVQENSRGCEYRFPPASSYNRMLIHRTAAFFGMEHNVDTETQQCVIVAVAKNTRIPEIR-FQSLVRDDARKSILKRDTHSFDEVRQSPYLCPLSLDRKAKSFEEREEDYDRARSRIFSRTGGNHDGYSGGGGDEECYGGWEQQQQQQKQSQPPRPKRPNGKMLQMQNSTESRDGMRSGGAVPKSHNFGNYGGPPSSGGPGNNSLPRGDSTNSIKSGRGGFVKQDSTGSTPWRLSPSSSGSIYHYDPSNLPPNQALQHSGNQYQSQNQGNSSSGGYNNYRKSSPHQQQQSQQQQQSQQHHQQQLQQPQQLHQQSSQQYATTELSCSSTESYAEEEAQSPGMECSEGYESYEQQSLPVQQQLSGNGDSASTKGDDCDSLASATACLSITTSTSTKNYDRIEVQKYKNQATSPNIPACCAVGEKLELEAGLPQEQEQEPMAGPSSSGSATSSVGITELPSSQTPLPMVNQVNCDLQSVSPSTTPYSQCEVKTPSQNHAPSAAVEEPKTTTWTYTQSYQAPDGSTVFHTTTTPNGAAPYCATTYQQGPDGSIYAVPQGMVYAAYPQPGVGTAGGASQPLFQLTTSSHPPAQTIFASPEAGAEIPGGTYMIPVFDPAQQPREGLIPAQAIYQTGPGGPGATTVMPMATAAAYPTAQFATAAPNGAPIYQAPLIYSSEPGGGAQLQQLPMAPYPIQYSYPYYHPISYYVPQQAVAAAPMVASQPQVGQAPMQQQAPHTGAGTTTGPPTVVSVSGQQHHQPHQQHHQQQQHSSNGSVVTSSAYGTRVKRTPGGGSIHYNPSYTPSSVAHAGGAHHPSAGSAQIIAAPAASTTTYHALPTLTLAHGGPATGTDLSGAGGAHVYALPAQHALIPTNIFPYAAAAAAAAGGPGGPPTTPQVVQQAPPPPPQSAPHHALITAAPFYPANGGNMDQGASQSAPSTPAAPGRQAPLFSTPPAPNNGSSGSSSAGGGGNSGGYHSNSSTPHYYQGQNSNEGYTSPYEKRNHGGGASGAHSVGVRKPYHPGGYNPRHSVPLGGIPSGAKTPLLNSNNEPTPRASPSSVSLGGASSSGGANSYPHRGPPPHTMGVKRDNKPNQLPLISGPPPSYAANSSPGVSSYESKPPVRLNAGAASFRSQKSMNQDYRRSVSQRNSPSANGGGSGSHESSNNSPNSIVGSQSNSAANTPNAAAPPPPQPQPTLVSHSGGFVVLDQTTGAAMNASPPSLYGGGGGPNAGISGGAGASGAAGSNGGHQPGGGGGARSHIPTAQLHHSAAAAAAAAAGSQQATAAVLSGVAAAAALGGYNPNGASGVYFKYGQTYFAHPSVALPNSRRSPSNDIRPQMAQVAGMYPTMMIQARHPSRHPNPNYKGSRPR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05672-1", "uniprot_id": "RBS1_YEAST", "id": "Q05672-1", "name": "RNA-binding suppressor of PAS kinase protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTALDSRNWGLTPAMETGLFQKPQDRIFIIELENSIVSFINSNTESFQ--LRPMNSYYRLLSHQIAEYHNLNHVLARTQDSCVILFKGENFQKIEGKPLLQELQLNKKPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ECASSSESIEKSNNNRIFRILKRKEVGNECDYKIDG---------NTRTPNSNLTANSNK-------------DQKIEIDDKSSTDLEQERIEKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLYEQRKQEIFDKLNKSEDDVKSTNSSGSSDSDNEWSDWLNGDDSN-----------------------------------------TQTSNGSVSSSSP---FNSSVTTIQVNKPQQQFYDSRRGRGGRRRGTNNYKDAYRGQSRRNKENGGYQSG------YSSPYLVYP-----------PPQMGGNSLPTYPLMYNPAGPAP-----------------------------------------------------------------------------------------------------------------------------------------------------GPAPSPMVMGNN-------------------------------TVFMNPYMYNMNPQGSCSFGTP----IPMYPPYQYQYQYQYNTQYHSG-PYSNTPSYNSNNYTRSSANKYHHFQGKNSYSGAIPKRSDDSNSNKN-----------------------------------------------------------------------------------------------EGIRRASVEGSPSSRDTDSVEMKFDKLNI-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .* : * ::*:** :::::*:.::.*: .* : : .** *:* *: * :..::* : ..**: .. : : : : . :: : . .. :::.: ::. . . : .. . ... ::: . : . * . . . : *. : . . * . . . . . . . . . : . . .* . : : * .. * * ..* .*:. : .. : . . . * .. : . . . :. . . . * . . : . * .... . :: : ", "identical_positions": 30, "similar_positions": 129, "identity": "1.65%" }, { "cls_id": "homologset.agr.SGD:S000002349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GAW9-1", "uniprot_id": "A0A8I6GAW9_RAT", "id": "A0A8I6GAW9-1", "name": "Ubiquitin conjugation factor E4", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------VPGPSQSLGLNVHNTTPATSPIGAAGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIATAARSPDRNLMLNTGSSSGTSPMFCSLGSFSASSLSSLYETSPAPSTSLWSFVPGLSPSFASPSHTAPAASPHSSAPQGAVASQSLSPQSAATHPLSPHSVAPQAAVPSPSLSSHSTASVIATGSQPSSPRYRPYTVTHLWGSSPCPTPRSSILANPPGFPAHSSSPRAVPASSSRQRPRSRAPAFPPASPSAASRRPSSLRISPSMYDSPFSSLFLALSGDSSEEEEEEDEEDDDEGGGDDDFSCVQFGSSLGASGGASTWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLARAAKECSLDSDYFKYPLMALGELCETKFGKTHPMCNLVASLPLWLPKSLSPGSGRELQRLSYLGAFFSFSVFAEDDAKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAAIVNANMKKAQMQADDRLVSTDGFMLNLLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRINATMEDVNEWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLMLRVLDPAYPD----ITLPLN---------------SEVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QVLYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPSVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNQEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHLLTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPTDPFNRQMLTESMLEPVPELKEQIQAWMREKQSSDH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES00-1", "uniprot_id": "UBE4B_MOUSE", "id": "Q9ES00-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------APGPSQSLGLNVHNMTPATSPIGAAGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIATAARSPDRNLMLNTGSSSGTSPMFCNMGSFSTSSLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLGASGGASNWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLESDYFKYPLMALGELCETKFGKTHPMCNLVASLPLWLPKSLSPGSGRELQRLSYLGAFFSFSVFAEDDAKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAALVNANMKKAQMQADDRLVSTDGFMLNLLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRINATMEDVNERLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLMLRILDPAYPD----VTLPLN---------------SEVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QVLYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPSVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHLLTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTV-MDRSIILRHLLNSPTDPFNRQMLTESMLEPVPELKEQIQAWMREKQSSDH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95155-1", "uniprot_id": "UBE4B_HUMAN", "id": "O95155-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------APGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSR-----------------------------------AASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSG-----VSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP----------------------------------------------SLGASGGASNWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLLLRILDPAYPD----ITLPLN---------------SDVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5A9-1", "uniprot_id": "F1Q5A9_DANRE", "id": "F1Q5A9-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEQLSPEEIRRRRLARLAGGQTSQPSTPLSTPLTSPQRETPPGPLPGPSGASSQPVPPAPSHTLALNAQNVTPATSPMGASGVAYRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDTASCEKS-MSQVDVDSGIENMEVEDSDR---------REKRNLAEKDSSSNPDVSEELALQLICKILRVSWKEQDRDVIFLPSLAAEFQKNPKDVYSDFKDLIGQILMEALMMSTRSRDCNPFASLTATSQPIT-AARSPDHHLTLVPPSSQGGSPMMPCAGSFGASSLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLGASAGGMAGDSGSDRFTIESCKETEMLNYLIERFDSVGMEERKAPKMCSQPAVSQLLSNIRSQCISHAALVLQGALTQPRAPLQPSLLVPYMLCRNLPYGFIQELVRMTHQEEDVFKQIFVPILQGLALAVKECSFDSDNFKFPLMALAELCEIKFGKTHPVCNLITSLPLWCPDPLSPGTGREIQRLSFLGAFFSLSVFAEDDTKVGDKYFSGPAITMENTRVVSQSLQHYLESARGDLFKILHNILLNGE-TREAALSYMAALVNRNVKKAQMQTDDKLVSTDGFMMNFLWVLQQLS------MKIKLETVDPLYIFHPKCRLNVSPEETRLKATMEELKSWLTELHEDPTKFSEPKFPTECFFLTLHAHHLSILPCCRRYIRRLRAIRDLNRTVEELKNSENQWKDSPLAGRHREMLKRCKTQLKKLVRSKACADAGLLDENLLRRCLQFFSMVIQLILRMVEPAFPH----VSLPLN---------------PEIP-KSFAALPEFYIEDVAEFMLFIVQYFP-QVLYEPCTEDIVTFLIVFICSQNYIKNPYLIAKLVEVLFVTNPAVQPRTQRFFEMLENH-PLSVNQLVPALMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNINHQG--TFLEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEIQEEMKNKEQWDLLPREQQ-QSRQSQLTQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNYNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCPR-FAKAIADDQRSYSRELFEEVISKMR-KAGIKSTIAIEKFKLLLEKVEEIVARNSQSEMDYSDAPDEFKDPLMDTLMTDPVQLPSGNI-MDRSIILRHLLNSPTDPFNRQPLTESMLEPVPELKERIQAWMREKQTGRY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK44-1", "uniprot_id": "Q9VK44_DROME", "id": "Q9VK44-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "MPEEEPPQKPMEEEEDDDQEQDQDQDHEQDQHEQDQQPQLAQGEIPGQQLPEQPNPDVQ-------PQQPAESVVVTELSAEEMRARR-LRTLAARSGIQCALAPLTTTPRKPTNVSGESRLVREATPGEKEVSLPTSAPAWRELSGKPDMDVEMKSVVSTPMQDVDMTTALSLPTAEATKRSVLQSCKISAGNAELSIETVVGPKKSADEQNEQLLSRLLNATWNEYGSGSIICAQSASFLEQQPHRRFDFECIVANVLMEAVLKIYNGELIEGDGVSVKADDKEFSSAKKIKSDDTEVQEILANAVATGGATASGETAAAAAGASG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEATSSEAAGTCVAPPVLSIVATTKHHVLLYLIRCYQNYQTECSRKTPLTQPALQLAFEQVMRMTVLVLTDRIYQN----LNGHMDQSALLDLMYMAKVSEPFLIDLIAHTHQDREAFDTIFSQVLRGLFAGMQRNICTSKISVQQIEWLSKLVVIKVGSVRPIADLVSRQPNFLPPICTKISGREIVKCSFLGPFLSVSLFAEENIKFAEFTTKN-----KLEDASSSRLRWELHSMRTNMHVVFHSLCVNAS-SRPKTLEYIASILRHNDRRVQFASDEKLLARDGFMINLMSVLQQLS------VKIKLDRIEPNFHYYKNSLVNIEQD-TKIRYSEEEYRNFLARDFS--QPVENTNFQTQCWFLTLQAHHLGYLPAIQRYRQKVRAIKELQKLIDELDRTKSHWMNSRYANRNNQFKERWEKQLRKLNRSKTCCEITLLDPGLLQRCTEFYSTVCEFMLYQFEGRPIEGPFISKLPVQ---------------QLLPTDAFSALPEWYIDDIAEFILFTMQHAN-MDIRQGIDHSIITWLLTCVCASHLIKNPYVTAKLVEVMFVFS---LKPANSVNAAMWNH-ELAQNALVSSLMRFYVDVETTGQSTEFYDKFTIRYHISHLFKSMWENPIHRQ--AVICESRVGNQFVKFVNMLMNDTTFLLDECLENLKRIHQTQQLLSDKANLSKMSAEQQ-QSRLTQLATDERQCRSYLTLARETVDLFHYLTSDIKEPFMRDELVDRLSSMLNFNLKQLAGPKCNDLKVKNPAKYGWEPRSLLAQIFDIYLHLDCDR-FAEALAADERSFDVQICNEAASRIK-RLALRSAVEVERFKALTQRAHEIYVTNLQTEDECADAPDEFKDPLMDTLMSDPVVLPSGTV-MDRAIITRHLLNSCTDPFNRQPLTEDMLVANIELKQRIDAWRKEQRGKRNNC---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54860-1", "uniprot_id": "UFD2_YEAST", "id": "P54860-1", "name": "E4 ubiquitin-protein ligase UFD2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLLYQLTENE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLDKPFEYLNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVALQIENFCMNGAFIN-YITGIVSNVNSYTDFLSQIIQRAILEGTALD-LLNAVFPTLLEYCNKHVSHFDLNESVIYNNVLTIFELFVTFKPIAEIFTKIDGFFADYSCK--PQDFERKTILGPILSLS--PIEAAVAIRNYGDNLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSLNSRTDMISYFAHIANKNHLRRADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKIDKIDANYFNNPSLFIDLSGE-TRLNSDFKEADAFYDKNRK--TADSKPNFISDCFFLTLTYLHYGLGGTLSFEEKMGSEIKALKEEIEKVKKIAANH--DVFARFITAQLSKMEKALKTTESLRFALQGFFAHRSLQLEVFDFICGASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVENVDNADFLRAHAPVPFKYYPEFVVEGPVNYSLYISKYQTSPIFRNPRLGSFVEFTTMVLRCPELVSNPHLKGKLVQLLSVGAMPLTDNSPGFMMDIFEHDELVNKNLLYALLDFYVIVEKTGSSSQFYDKFNSRYSISIILEELYYKIPSYKNQLIWQSQNNADFFVRFVARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARGAPPTREEEDKELQTRLASASRQAKSSCGLADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVDILGRKTGLASPEFIEKLLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMKDPVILPASKMNIDRSTIKAHLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEEAKHKASE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :.: . : . : . . : ** : : . . : : * .. : : : *: ::: : : .:. :: :: * :. . : . . :*:.::.: : . ::: : : **.::*.* . : .. : . *: . :. :...: .. :* :.*:* : . * : . : :: :*** *: :* ::* *:: ::. : : : : *::. :: . .:.:* ::*:**** * . : *: *:. ::.:.. : . * .: :. *:. : . : : . .: . :* ::: .: .**: . * **: ::. .:: :: :: : : .:: : : . : **:: .***::: : : . : :* * : *: :*: **. ** ** :::*****. ** ** :::.:: : . . . .. **::: ::** ****** *..* .:*: *: :.:: . . ::: : ::*: .* .:* ** :::.:*. :.:: .*: *: **::***:**:.* **** :***::* .*.::*:.** : :*::*. * .*:* *:**:. :: .. . : : .: *. :*:: : ::..* : . : : .*.**** **** *:*.*** **:..: :**: * ***.. ****** *. . : . **:::* .: :::: ", "identical_positions": 150, "similar_positions": 315, "identity": "10.11%" }, { "cls_id": "homologset.agr.SGD:S000002350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWV7-1", "uniprot_id": "RL35_MOUSE", "id": "Q6ZWV7-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17078-1", "uniprot_id": "RL35_RAT", "id": "P17078-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42766-1", "uniprot_id": "RL35_HUMAN", "id": "P42766-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHJ1-1", "uniprot_id": "RL35_DANRE", "id": "Q8JHJ1-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAIRRQLTKHEENLMTKKMQRKSRLYSIR----------KFAVKA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M6G3-1", "uniprot_id": "F1M6G3_RAT", "id": "F1M6G3-1", "name": "Large ribosomal subunit protein uL29", "aln": "-----GSDLRGKKEEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVNSQTQKENLRKFFKGKKYKPLDLRPKKTGAMRRRLTKHEEKLKTKKQQWKERLYPLRTSTQSRTERMTMTIKCETDGKKKKKKEQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LHE8-1", "uniprot_id": "A0ABK0LHE8_RAT", "id": "A0ABK0LHE8-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLPSKEKEELLKQLEDLKVELSQLCVSKVTGGAASKLSKTGVIRKCSACVLTVINQTQEESLRKFYKGEKYKPLDLPPKKT--THRWLTKQEEELKTKKQQQKEWLYPLR----------RCAVEA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W499-1", "uniprot_id": "Q9W499_DROME", "id": "Q9W499-1", "name": "Large ribosomal subunit protein uL29", "aln": "MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQR----------KFAVKA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX84-1", "uniprot_id": "RL35A_YEAST", "id": "P0CX84-1", "name": "Large ribosomal subunit protein uL29A", "aln": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLS---RPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQR----------KYAIKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.:::* .** :** ** .* * *:: ..*.* .:**. * * * : *.* :*:.:*.:**:* ** *** :: *. : . * * * :. * :::. ", "identical_positions": 36, "similar_positions": 36, "identity": "24.66%" }, { "cls_id": "homologset.agr.SGD:S000002351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSL7-1", "uniprot_id": "ARF2_MOUSE", "id": "Q8BSL7-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84082-1", "uniprot_id": "ARF2_RAT", "id": "P84082-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84077-1", "uniprot_id": "ARF1_HUMAN", "id": "P84077-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84079-1", "uniprot_id": "ARF1_RAT", "id": "P84079-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84078-1", "uniprot_id": "ARF1_MOUSE", "id": "P84078-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61205-1", "uniprot_id": "ARF3_MOUSE", "id": "P61205-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61204-1", "uniprot_id": "ARF3_HUMAN", "id": "P61204-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61206-1", "uniprot_id": "ARF3_RAT", "id": "P61206-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P61750-1", "uniprot_id": "ARF4_MOUSE", "id": "P61750-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61751-1", "uniprot_id": "ARF4_RAT", "id": "P61751-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18085-1", "uniprot_id": "ARF4_HUMAN", "id": "P18085-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW4-1", "uniprot_id": "Q7ZUW4_DANRE", "id": "Q7ZUW4-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFGRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5M5-1", "uniprot_id": "Q6P5M5_DANRE", "id": "Q6P5M5-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*: *:*:*:*********.*****:********::*************:****.**********:**.**:**::**:*:*********.*: * : :** ***::*. *:*.******:** :*:*:****:*:* * *::******.* ******:**:*.* : ", "identical_positions": 118, "similar_positions": 40, "identity": "64.84%" }, { "cls_id": "homologset.agr.SGD:S000002352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFM4-1", "uniprot_id": "D3ZFM4_RAT", "id": "D3ZFM4-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "-------------------------------------------MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRNRRHHRHPHRGPGP----AATHPRLR--------WRADGRSLQKLPVHMGLVITEEVQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----QDCSKYSAEFAN-------------------SNDKDDQVLNCPSAVKVLSPEDGKADIVRAAQDFCQ---------SVAQQQRRPTELGVELLDSLLS-SHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIISLPSHSNISYEDLFSALRQYAACEQRLGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ8-1", "uniprot_id": "NGBR_MOUSE", "id": "Q99LJ8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit Nus1", "aln": "-------------------------------------------MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRNRRHHRHPHGGPGPGPGPAATHPRLR--------WRADVRSLQKLPVHMGLLVTEEVQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----QDCSKYSAEFAN-------------------SNDKDDQDLNCPSAVKVLSPEDGKADIVRAAQDFCQ---------LVAQQQRKPTDLDVDLLGSLLS-SHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E22-1", "uniprot_id": "NGBR_HUMAN", "id": "Q96E22-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "-------------------------------------------MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSCL----AAAHHRMR--------WRADGRSLEKLPVHMGLVITEVEQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----LDCSKYSPEFAN-------------------SNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQ---------LVAQKQKRPTDLDVDTLASLLS-SNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHR8-1", "uniprot_id": "NGBR_DANRE", "id": "Q6DHR8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit nus1", "aln": "-------------------------------------------MASLYEMVWRFLHALLYLQRAIVAWFRV------HIWR--WKLAVVDLLLPLALGFHNQKKTG--------PKG--------TRTSRRVR--------WGADGRTLEKLPLHVGLLVTEE---------EIHYTDIANLVVWCMAVGISYVSVYDN--QGVFKRNNSRLMEEILKQQQELLG----MGSSKYSVEILKN-----------------GTNKQEHQVLSCQSMVKVLSPDDGRLSIVQAAQQLCR---------AVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWHIRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12063-1", "uniprot_id": "UPPS_YEAST", "id": "Q12063-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLKGGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKFLLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAILEVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDY--DGILQRNVPELRMEIHSNLAKYFGP---AHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNRDGRETIVDLTKTMAE---------LCAVNELSVSDITMDLVDSELK-QLVGPEPDLLLYFGPSLDLQGFPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VPX8-1", "uniprot_id": "Q9VPX8_DROME", "id": "Q9VPX8-1", "name": "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]", "aln": "----------------------------------------------MIEVLCLLLGRILLLLVGGYELMWR-------------LRERLNALAVRSYDLWRSKAAR-------------------EAHERRVL---------ADCRSQLTKTPQHLVLVISPVDAG-------VDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQ----------------KTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLG--FEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQRWGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : : . . : * * * :: :: : :. : : .**.:: :** .* : . * . : . : .: : : . . : :* **: *. : : . :. .: . : . * *:*:* : *. *: **: *:**: . . . : * ::: *: . *.", "identical_positions": 28, "similar_positions": 67, "identity": "7.18%" }, { "cls_id": "homologset.agr.SGD:S000002353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDR--TITSFEVTKD-----AGSWVGGIMPLAALAGGITGGPLIEYLGRR-STILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGS-------FMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQN--------------TCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGG-FFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHG-----AFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDR--NITSFEVTQD-----AGSWVGGIMPLAGLAGGIAGGPLIEYLGRR-NTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGS-------FMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRN--------------TMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGG-FFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHG-----AFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKAS------------------DNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRG-EGYDFPVDKD-----QFSWVGSAMTLGAACVCIPIGFLINMIGRK-WTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGA-------GVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRET-KANKVN--------------VWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGG-----TFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPZ9-1", "uniprot_id": "Q8IPZ9_DROME", "id": "Q8IPZ9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSTGGDK------------------------------------------------------------------------------------------------------------------------------------------------------------------YQYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPT-----DQGWVASNICLGGLVGTFLFTWLADRIGRK-LCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGY-------YFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGT-YSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHG-----TVFMFASLSFLAAIFIAIFVPETKGKSVDAILASL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10870-1", "uniprot_id": "SNF3_YEAST", "id": "P10870-1", "name": "Low glucose sensor SNF3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MDPNSNSSSETLRQEKQGFLDKALQRVKGIALRRNNSNKDHTTDDTTGSIRTPTSLQRQN------------------SDRQSNMTSVFTDDISTIDDNSILFSEP-----------------------------------------------------------------------------------------------------------------------------------------------PQKQSMMMSICVGVFVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYEASFGSSN-------FIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTG-VSNSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAI-----VGCSLKTVAAAKVMIAFICLFIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTLEEIDELYIKSSTGVVSPKFNKDIRERALKFQYDPLQRLEDGKNTFVAKRNNFDDETPRNDFRNTISGEIDHSPNQKEVHSIPERVDIPTSTEILESPNKSSGMTVPVSPSLQDVPIPQTTEPAEIRTKYVDLGNGLGLNTYNRGPPSLSSDSSEDYTEDEIGGPSSQGDQSNRSTMNDINDYMARLIHSTSTASNTTDKFSGNQSTLRYHTASSHSDTTEEDSNLMDLGNGLALNAYNRGPPSILMNSSDEEANGGETSDNLNTAQDLAGMKERMAQFAQSYIDKRGGLEPETQSNILSTSLSVMADTNEHNNEILHSSEENATNQPVNENNDLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::.. * . .: : .: . . : . : *. : : : **: :: . :. : * : .*.: * * *:* .* .:** : . *::. . . . : . : : ::**:* . . :.* ::: : *. . * . . . : .:.* *:*..* :: * :* .:. ::: ::.. . . ..:: **: :* .. : : : :. . . . : :: : : : : : ::: .*: . ::. . : : *: . : . . .:::..: :. :.: : * **:* ::: * ", "identical_positions": 36, "similar_positions": 144, "identity": "3.0%" }, { "cls_id": "homologset.agr.SGD:S000002354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q1-1", "uniprot_id": "SC31A_RAT", "id": "Q9Z2Q1-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEIDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQ-PPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVVQMWDLRFASSPLRVLEN-HARGILAIAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRIRVYSIMGGSIDGL-RQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTSQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFEN-VTGQPQQGAEQPRRQP-VFISQVVTEKDFLSRSEQLQHVVQSQGFISYCQKKIDASQTDFEKNVWSFLKVNFEEDSRGKYLELLGYRREDLGEKIALALNRVDGSD----VALKDSDRVAQSD-GEESPAEEGQLLG-ERIKEEKQECD----------FLPSAGGGTFNISVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQE-LLAQTQKKYFAKS--QSKITRLITAVVMKNWKEIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGARLESEGDS--LLRTQACLCYICAGNVERLVACWTKAQDG--------------SNPLSLQDLIEKVVILRKAVQLTQALDTNTVGALLAEKMSQYANLLAAQGSIAAALAFLPDN------TNQPDIVQLRDRLCRAQGRSVP-------------------GQESSRSSYEGQPLPKGGPGPLAG----HPQVSRVQSQ--------QYYPQVRIAPTVTTWSDRTPTALPSHPPAACPSDTQGGNPPPPGFIMHGNVVPNSPAPLPTSPGHMHSQPPPYPQPQPYQPAQQYS-LGTGGSAVYRPQQPVAPPASKRYPNAP----YVSPVASYSGQPHMYTAQ-PASSPTSSSAPLPPPP-SSGASFQHGGPGAPPSSSAYALPPGT--TGTPPAASELPASQRT----------------------------GPQNGWNDPPALNRVPKKKKLPENFMPPVP-ITSPIMNPGGDPQPQGLQQQPSASGPRSS---------HASFPQPHLAGGQPFHGIQQPLAQTGMPPSFSKPNTEGAPGAPIGNTIQHVQALPTEKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLECLYDKLRDQ-TLSPTIISGLHSIARSIETRNYSEGLTVHTHIVSTSNFSETSAFMPVLKVVLSQASKLGV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UPL0-1", "uniprot_id": "SC31A_MOUSE", "id": "Q3UPL0-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEIDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQ-PPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLEN-HARGILAVAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSIDGL-RQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQSAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFES-VAVPLQQGAEQQRRQP-VFISQVVTEKDFLNRSAQLQHAVQSQGFIGYCQKKIEASQTEFEKNVWSFLKVNFEEDSRGKYLELLGYRKEDLGQKIALALNKVDGPD----VALKDSDQVAQSD-GEESPAAEEQLLG-ERIKEEKQECD----------FLPSAGG-TFNISVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQE-LLAQTQKKYFAKS--QSKITRLITAVVMKNWREIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGTRLEREGDS--LLRTQACLCYICAGNVERLVACWTKAQDG--------------SSPLSLQDLIEKVVILRKAVQLTQALDTNTVGALLAEKMSQYASLLAAQGSIAAALAFLPDN------TNQPNIVQLRDRLCKAQGKPVS-------------------GQESSQSPYERQPLSKGRPGPVAG----HSQMPRVQTQ--------QYYP-------------------------------HGENPPPPGFIMQGNVIPNPAAPLPTAPGHMPSQLPPYPQPQPYQPAQQYS-FGTGGAAAYRPQQPVAPPASNAYPNTP----YISPVASYSGQPQMYTAQ-QASSPTSSSAASFPPP-SSGASFQHGGPGAPPSSSAYALPPGT--TGTPPAASELPASQRTENQ---------------SFQDQASILEGPQNGWNDPPALNRVPKKKKMPENFMPPVP-ITSPIMNPSGDPQSQGLQQQPSTPGPLSS---------HASFPQQHLAGGQPFHGVQQPLAQTGMPPSFSKPNTEGAPGAPIGNTIQHVQALPTEKITKKPIPEEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ-TLSPTIINGLHSIARSIETRNYSEGLSVHTHIVSTSNFSETSAFMPVLKVVLSQASKLGV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94979-1", "uniprot_id": "SC31A_HUMAN", "id": "O94979-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQ-PPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLEN-HARGILAIAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGL-RQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFEN-VRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGAN----VALKDSDQVAQSD-GEESPAAEEQLLG-EHIKEEKEESE----------FLPSSGG-TFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQE-LLARTQKKYFAKS--QSKITRLITAVVMKNWKEIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGTRLENEGDS--LLQTQACLCYICAGNVEKLVACWTKAQDG--------------SHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDN------TNQPNIMQLRDRLCRAQGEPVA-------------------GHESPKIPYEKQQLPKGRPGPVAG----HHQMPRVQTQ--------QYYP-------------------------------HGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYP-FGTGGSAMYRPQQPVAPPTSNAYPNTP----YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGT--TGTLPAASELPASQRT----------------------------GPQNGWNDPPALNRVPKKKKMPENFMPPVP-ITSPIMNPLGDPQSQMLQQQPSAPVPLSS---------QSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ-TLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKLGV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYD5-1", "uniprot_id": "SC31A_DANRE", "id": "Q7SYD5-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEINRTAIQAWSPAQQHPIYLAAGTSAQQLDATFSTNASLEIFELDLADSALAMKSCGSFSSPHRYHKLVWGPHGIENQGLPSGVLIAGGENGNIILYDASKIIAGDSEVIISQSEKHTGAVRALDVNSFQSNLVASGGNESEIYIWDLNNFS------SPMTPGPKTQ-PQEDISCVAWNKQVQHILASASPSGKASVWDLRKNDLIIKVSDHSN----RMHCSGLAWNPEVATQLVLASEDDRMPVIQMWDLRFATSPLKVLEN-HTRGILAIAWSVADPELLLSCGKDNRILCWNPNT----AEVLYELPTSTQWCFDIQWCPRNPAVLSAAAFDGHISIYSIMGGSNDNA-NNLQADQLSSSFGNVDPFGTGKTLPPLQLPQQTSPQSTITPLKKPPKWIRRPVGASFAFGGKLVTLDN-IKPTAQQ--PQQTAAHVVHISQVVTETDFIHRSNQLQTTLNAGNFLEYCQNKIETVQNEFERTVWSFLKVNFEEDARLKYLELLGYEKEELALKIASALEGNCKPK----EADMDKEEVLAEE-EAESDLDDIPVNEEEPVVEETSNTE----------VPPAPASDAINLKVSQDIDGLITQALLTGDYEAAVNLCLHDNRMADGIILAIAGGPE-LLAKTQRKYFSKT--ESKISKLISAVVMKDWLDILETCDLQNWK--EALAAVMTYAKPEEFSALCGLLGSRLESSEDV--ELQAQACLCYICAGTVEQLVSFWTKTQDS--------------CSPLSLQELVEKVVVLQRAVEKAQGAVPADMGALLAEKMNQYASLLASQGSLQTAISYLPTN------TEQVSVQQLRERLSRALGQHQH-------------------LQQPAAAVTGIQKMHQRRPAAVPMQTYTQPQPPQVPAQPAAPAVPPQYYQQGRSATTVTSWSNQTPTALPSVPRQLVPSSDPQGDSTPPAFGLQS----PAMASVPASTPFMYSQ-----QYQNYPPVQQFT-PSAGTPGIYQP-LPYASSAGAPLPPPP----SSSSSAAVYPPQFMLSASSQASAPPQSFCP--PPAVSSGGCFQHGGPGSPTS---YLPPPGARAPGTQHEPALIPASQRTDG----------------FYQETAWGLEGPQNGWNDPPALSRAAKKKKVPQHFTPPAP-ITAPIMAPLGDPQAPAGMQTLQPQQQVPD---------QSAGPATFT----PIQ--QQPLGPR--NPSMPQGNMEGAPGAPIGDVIKPLQAIPTEKITKKPIPEEHMVLKTTFEGLIQKCLTAASDPQTKRKLDDAHKRLELLYDKLREQ-TLSPAIIGGLHNMAQSIECRSYADGLNIHTHIVSNSNFSETSAFMPVLKVVLTQANKLGV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U4U0-1", "uniprot_id": "A0AB32U4U0_DANRE", "id": "A0AB32U4U0-1", "name": "Protein transport protein Sec31A", "aln": "-MRVKEILRTATQAWSPARQHPAYLALGTAAQQLDASFNTSSALEIFDMDFSDTSMDMKLRGTLATSNRFHSLIWVAFGMDVQ-PSSGRLIGGSENGSVTVFNPDVILTAGEDAVIGQSNKHTGPVRALDFNRFQSNLIASGANDSEIYIWDLNNFS------NPMTPGTKSQ-PAEDVSVVAWNSQVQHILASANPSGKAVVWDLRKNEPIIKISDHSN----RMHCSGMLWHPDVATQLVLASEDDRLPVIQMWDLRFATSPLKVLEN-HTRGILSISWSQADPELLLSSGKDNRILCWNPNT----GEVIYELPTANQWCFDVQWCPRNPALLSAASFDGRISVYSVMGGRLQQQ-QHSTVDQISASFDTNDPFGMGQTLPPLQVPQAAVETTIIPPLKKPPKWVRRPVGASFAFGGKLVTFENPNVAPPQQQQPANPLPRQVHVSQVTTETEFLQRSTELQMTLQSGSFSSFCHSKIQSAPTDAEQDIWRFLMVNFEDEARVKFLRLLGFSKDELQRKISACLGRKLQPNGLDVNDLAEKMQTLSDQRADECAGAADGLPGGESPADFFSQLP----------KKEKDKQ-PFQIPVSSDTDGLISQALLVGNFEGAVDLCLNDGRFAEAILLSISGGEE-LLKKTQQRYLQRQ--TNSISMLISSVVTQNWRDIVQSCELDNWK--EALAALLTYANPEEFASLCDTLGSRLEAGGSE--KLCLQACLCFICSGNIERLVDCWTLQRDC--------------SSPLALEDLVEKVMILRKSIERLRNTEVCVRSSALTQKLIQYSSILASQGSLSAALNYLPSD------SDQAAVRMLRDRLSHAKGEIQQKP-------------SAPAGGAKPAPNTHTPAAHTTAPYPSSG----APQMPRLFSP--------QTGPE--------------------------PPAGATTHTPRPAYTQHPATAPGFHPFPPAAPQGAPGG-----FFTPQMPSSSLAGPSMPPSSPPGPMMPAGVPMMMPTPPAPG---FLSPTSLPGGPRFPGSAHTQGPAPPPTGAY----PSLGAAGYPQGGPGAPAAKSFSGAPVPP--PPSGYFPWLTYQTQEE----------------------------GAQDGWNDPPAVRAGQRKKKLPENYTPPAP-ITAPVMG--FPAEAPVLQDRVQVP-----------------------------------------------------PGAPQEPSIQSIQQLPAERVEQKEIPAEHVILKTTFSSLVQRCQLAAADPQTKRKLDDASKRLENLYDKLRDQ-SLSPSILGGLHEISRCVSARSYVQGLEVHTQVVSSSNFSEISAFMPVLKVLMTIANKLAV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TZ89-1", "uniprot_id": "SC31B_MOUSE", "id": "Q3TZ89-1", "name": "Protein transport protein Sec31B", "aln": "-MKLKELEKPAVQAWSPARQYPVYLATGTSAQQLDASFSTNATLEIFEIDFRDPSLDLKHKGILSVSSRFHKLIWGSF-GSGLLENSGVIAGGGDNGTLTLYNVTHVLSSGKEPLIAQKQKHTGAVRALDFNPFQGNLLASGASDSEIFIWDLNHLS------VPMTPGPKSQNPPEDIKALSWNLQVQHILASAHPSGKAVVWDLRKNEPIIKVSSHSS----RMNCSGLAWNPDIATQLVLCSEDDQLPVIQLWDLRFASSPLKVLES-HSRGILSMSWNQADAELLLSTAKDSQIFCWNLSS----SEVVYKLPTQSSWCFDVQWCPQSPPVFSAVSFDGWISLCSVMGRSWEAQ-HMRQADKV---------------------PEQVAQASLIPPLKKPPKWMRRPAGGSFAFGGKLVTFGL---PSIPVQPVAQACSRPVFISQVITESEVLTRSVVLQEALGSGNLLNYCQSKVQQASLPCEKILWQFLKVTLEQDSRPKFLGLLGYSREELQKKVDTCLKSDSKSQ----ESPQLEAVDLKSD-RAHSPCAQASKHTAKEASESSAFFD----------ELIPQNMTPWEIPTTEDTDGLLSQALLLGELRSAVELCLKEERFADAIILAQAGDAE-LLKWTQERYLAKR--RTKTSSLLACVVKKNWKDLVCACRLKNWR--EALALLLTYSGPEKFPELCDMLGTRMEQEGGR--ALTSEARLCYVCSGSVERLVESWAKFQQA--------------SSPMALQELMEQVTVLSRSLELLQGSNKMSPGPATTHRLTQYANLLAAQGSLATAMSFLPSD------CIQPGVQQLRDRLFHAQGSAVL-------------------GQQAPAFPFPRVAVGAALHSKETS----SYRRGLQPPQ-----------------------------------------QVPAPSVRPRT-TAQPSSVMPFSPSQPSPSQG-----SSDHRVLRPQAILPGHFVPGVRPALSPPQLSGGQSVPAVNPAGFCGAWPLPGPTPVMASPDFMQPGSTHLPETPRLLPLPPVGPPGPNPLSSQLPASPVTFSVAPPPGGPRAPCSSALPSSGILATCP----------------------------GPQDSWKVSPASQGNLQRKKLPETFMPPAP-ITAPLRSLGPEPQQALLPQPLVSSATLP------------------------------------------------PPGAPRECSLQQLQPLPPERTE-KELPPEHQCVKDSFEALLQRCSLTATDLKTKRKLEEAARRLECLYEKLCEG-TLSPHVLAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPMLKAVLTIAHKLQG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L020-1", "uniprot_id": "A0ABK0L020_RAT", "id": "A0ABK0L020-1", "name": "Protein transport protein Sec31B", "aln": "-MKLKELEKPAVQAWSPAKQYPVYLATGTSAQQLDASFSTNATLEIFEVDFRDPSLDLKRKGILSVSSRFHKLIWGSS-SSGLLENTGVIAGGGDSGMLTLYNVTHILSPGKEPLIAQKQKHTGAVRALDFNPFQGNLLASGASDSEIFIWDLNHLT------VPMTPGSKSQNPPEDIKALSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSS----RMNCSGLAWNPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLES-HSRGILSVSWSQADAELLLSSAKDNQIFCWNLSS----SEVVYKLPTQSSWCFDVQWCPRNPPAFSAVSFDGWISLYSVMGRSWEAQQHMRQADKV---------------------PEQVAQASLIPPLKKPPKWMRRPAGVSFAFGGKLVTFGL---PSIPVQQVPQPCPRPVFISQVITESEFLTRSVVLQEALGSGNLLNYCQSKIQQASRPSEKTLWQFLKVTLEHDSRLKFLRLLGYSRDELQKKVDTCLKSDSKSQ----ESPQLEAVDLKSD-RAHTLCSQASRHTAKEASASSAFFD----------ELIPQNMTPWEIPTTEDTDGLLSQALLLGELRSAVELCLKEERFADAIILAQAGDAE-LLKWTQERYLAKR--RTKTSSLLACVVKKNWKDLVCACSLKNWR--EALALLLTYSGPEKFPELCDMLGARMEHEGGR--ELTSEARLCYVCSGSVERLVESWADSQQA--------------SSPVALQELMEQVTVLSRSLELLQGSHKMSPGPATTHRFTQYASLLAAQGSLAIAMSVLPSD------CTQPAVLQLKDRLFHAQGSTVL-------------------GRQAPAFPFPRVAVGAALHPKETS----SHRMGFQPPR-----------------------------------------QVPAPSVRPRA-AAQP-SVMPFLPSHPIPSVGSWTQSSSDYRVPKPQATLPVHFVPGVRPAFSQPQPFGGQSVQAINPVGFCGTWPLPGPTPVMAPPDVMQPGSTHLPETPRLLPLPPVGPPGPTPLSSQPAASPVTFSVAHPPGGPGAPRSSALPSSGILATRP----------------------------GPQDTWKVAPASQENLQRKKLPETFMPPAPIITAPLMSLGPEPQQALLPQSLVSGASLP------------------------------------------------PPGAPRECSLQQLQPLPPEKTQ-KELPPEHQCLKDSFEALLQRCSLTATDLKTKRKLDEAAHRLECLYEKLCEG-TLSPHVLAGLHEVARCVDAGSFEQGLAVHAQVVSCSSFSEVSSFMPVLKAVLTIAHKLQG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQW1-1", "uniprot_id": "SC31B_HUMAN", "id": "Q9NQW1-1", "name": "Protein transport protein Sec31B", "aln": "-MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHRGVLSALSRFHKLVWGSF-GSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLN------VPMTLGSKSQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLES-HSRGILSVSWSQADAELLLTSAKDSQILCRNLGS----SEVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQ-HMRQADKISSSFS------KGQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGL---PSTPAHLVPQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLG----ESPQPKGNDLNSD-RQQAFCSQASKHTTKEASASSAFFD----------ELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGGTD-LLKQTQERYLAKK--KTKISSLLACVVQKNWKDVVCTCSLKNWR--EALALLLTYSGTEKFPELCDMLGTRMEQEGSR--ALTSEARLCYVCSGSVERLVECWAKCHQA--------------LSPMALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRD------CAQPPVQQLRDRLFHAQGSAVL-------------------GQQSPPFPFPRIVVGATLHSKETS----SYRLGSQPSH-----------------------------------------QVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHP----------------------------GPQDSWKEAPAPRGNLQRNKLPETFMPPAP-ITAPVMSLTPELQGILPSQPPVSSVSHA------------------------------------------------PPGVPGELSLQ-LQHLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEG-TLSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LEZ1-1", "uniprot_id": "A0A0B4LEZ1_DROME", "id": "A0A0B4LEZ1-1", "name": "Protein transport protein Sec31A", "aln": "-MKIKELQKTVNIAWSPAQQQQILLAAGTAAQQFDS--NANSTLELYSPNFSDATYDLELRASVSSQYKFQKLIWSPV----GPHPSGLIVGGCEAGQINIYSADKLLAGKEEPLLKRQDKHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPE------TSMSPGTKTQ-PLEDVKNVAWNRQVQHILASVFST-RCVIWDLRKSQQIIKLSDSQS----RVRWHAIEWHPEAATQVWLASEDDQAPVVQLWDLRYATAPAKTYQI-HERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIPEGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGTHHLV---QTANKIADSFP-------GMDQFAQEPIPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFNG--------------TSKTVKVQQLTTESALVDRANALERSLVDANYSDYCRQRADETPDQHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHSDSSEVECDQSTNYSTDNSQTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIE-TLNRTQTRYLLQQ--KNELSHVISALVSRDWLDFVNRCTVDSWK--EALVAALKHSE-RKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPG------YKPNTTELQDLAEMVMLMCKSLEQQG--ISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQP-------------QAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPS---------------------------------WPAQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRN---------------------------PTPPPGWNDPPALKSSRAPK--PKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPLGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDG-KLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38968-1", "uniprot_id": "SEC31_YEAST", "id": "P38968-1", "name": "Protein transport protein SEC31", "aln": "MVKLAEFSRTATFAWSHDKIP--LLVSGTVSGTVDANFSTDSSLELWSLLAADS---EKPIASLQVDSKFNDLDWSHN--------NKIIAGALDNGSLELYSTN--EANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMS-SVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPES----AEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESE----------TDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQITP----------------DGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGE--------------------------------EFFQQIETNFQ-----------------PEGDFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHR-----QDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFINGSSTINNEQ----LIAKFLEFINLTTSTGNFELATEFLNSLP-----SDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFN-------KPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTP-KEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATN-HAQEGGNWLTGVKRLIGIAEATLN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *. :.. *** *. ** : .*: .:..:**::. *. : . . :::.* * . : .. : * : ::. : : : .:*:..* :..* * *::** ..:.** ***:*: .:: * . . . ::: ::** . *:::*. .: . :***: .. :*::* . : . : *:*. :*:: .: .*. * : :**** *.:* :. : * :*:*.: * * .*::: .:* : * : .* : :..: .* . ::.*. * ::..:::. : : :: . ..: * .. : . . . :.****** : :. .: : *. : . ..: . * :: .. *.: .:: : . .. . : ::. :: *: **. .*. : :.:::: .. : .: *: : .. : :: .: :: :.: :..*: . : : : ** *: :: ::.:*.::::. * . * :: * . :: . :: . :: .: :: * : * : . : : *: * . . . . . . .. . . . . ... *: . : . * .. :* : : :. : : . .::: : :**: *: * . *: *:.: :. .: :.: :*:::. : . :: :* :: * ", "identical_positions": 99, "similar_positions": 316, "identity": "7.1%" }, { "cls_id": "homologset.agr.SGD:S000002359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24528-1", "uniprot_id": "MGMT_RAT", "id": "P24528-1", "name": "Methylated-DNA--protein-cysteine methyltransferase", "aln": "----MAEICKMKYTVLDSPLGKIELSGCERGLHGIRFLSGKTPNTDPTEAPAC-------PEVLGGPEGVPEPLVQCTAWLEAYFHEPAATEGLPLP---ALHHPVFQQDSFTRQVLWKLLKVVKFGEMVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVIRSDGAIGNYSGGGQTVKEWLLAHEGIPTGQPASKG-LGLIGSWLKPSFESSSPKPSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26187-1", "uniprot_id": "MGMT_MOUSE", "id": "P26187-1", "name": "Methylated-DNA--protein-cysteine methyltransferase", "aln": "----MAETCKMKYSVLDSPLGKMELSGCERGLHGIRLLSGKTPNTDPTEAPAT-------PEVLGGPEGVPEPLVQCTAWLEAYFREPAATEGLPLP---ALHHPVFQQDSFTRQVLWKLLKVVKFGETVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVVRSDGAIGHYSGGGQAVKEWLLAHEGIPTGQPASKG-LGLTGTWLKSSFESTSSEPSGRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16455-1", "uniprot_id": "MGMT_HUMAN", "id": "P16455-1", "name": "Methylated-DNA--protein-cysteine methyltransferase", "aln": "----MDKDCEMKRTTLDSPLGKLELSGCEQGLHEIKLLGKGTSAADAVEVPAP-------AAVLGGPE----PLMQCTAWLNAYFHQPEAIEEFPVP---ALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGG-LAVKEWLLAHEGHRLGKPGLGGSSGLAGAWLKGAGATSGSPPAGRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76339-1", "uniprot_id": "O76339_DROME", "id": "O76339-1", "name": "Methylated-DNA--protein-cysteine methyltransferase", "aln": "MTMWIGQNTQIRLVPLKDPPKTIRYSFLATKFGQMMMGVINPISGDSKDQVAIGVLHFVIKDNVSTYNEVQERWPKSELWKDDDAVKLVADKLFESDKENSQAIPIAIYGTDFQLSVWRALVHMKRGETCTYSQLAERMGRPTAVRAVASAVAKNELAILIPCHRVVSQNGAS-KYHWG-AALKQLLLADEKSKNY------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26188-1", "uniprot_id": "MGMT_YEAST", "id": "P26188-1", "name": "Methylated-DNA--protein-cysteine methyltransferase", "aln": "----MKELLYYTFIETEVTGAFLVFREKTQNLVFASLGNDKLFLLGKVEGFLKK------HEKQDTMYDLQELKEAETYKKSIENYTICLENKMPLP--SGAIPFEFLFGTDFQRKVWNELLNVEHGHVVTYGDIAKRIGKPTAARSVGRACGSNNLALLVPCHRIVGSNRKLTGYKWS-CKLKEQLLNNEKENSLSLSRL-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : : . : . . : : . : : :*. * :: *. :* ::* *.*.*.*:*. * * :.:*:****:: .. * . :*: ** .* ", "identical_positions": 22, "similar_positions": 41, "identity": "9.73%" }, { "cls_id": "homologset.agr.SGD:S000002360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R637-1", "uniprot_id": "M0R637_RAT", "id": "M0R637-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "--------------------------------------IMAGAEAPQPQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPPNQNKSHDDPKDEKEKHSGAQVEFADIGCGYGGLLVALSPLFPDTLILGLEIRVKVSDYVQDRIRALR--ATPGGGFQNIACLRSNAMKHLPNFFRKGQLAKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDVLELHEWMCTHFEEHPLFEHVPLEELSEDPVVEHLGTSTEEGKKVLRNNGKNFPAIFRRIQDPLLQAVTPNPTLP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z120-1", "uniprot_id": "TRMB_MOUSE", "id": "Q9Z120-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "--------------------------------------MMAGAEAPQPQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLIQNKSHDDPKDEKEKHSGAQVEFADIGCGYGGLLVALSPLFPDTLILGLEIRVKVSDYVQDRIRALR--AAPGGGFQNIACLRSNAMKHLPNFFRKGQLAKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTVTDVPELHEWMCTHFEEHPLFERVPLEELSEDPIVEHLGSSTEEGKKVLRNGGKNFPAVFRRIQDPLLQAVTPNPTLP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBP6-1", "uniprot_id": "TRMB_HUMAN", "id": "Q9UBP6-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "--------------------------------MAAETRNVAGAEAPPPQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQAQVEFADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRALR--AAPAGGFQNIACLRSNAMKHLPNFFYKGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDVLELHDWMCTHFEEHPLFERVPLEDLSEDPVVGHLGTSTEEGKKVLRNGGKNFPAIFRRIQDPVLQAVTSQTSLPGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ57-1", "uniprot_id": "TRMB_DANRE", "id": "Q5XJ57-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "------------------------------------------MSVCMPQKRYYRQRAHSNPMADHTFQYPVCPEQMDWSPLYPQYFP-------------QQEEAGGAQVEFADIGCGYGGLLVQLSQLFPQQLILGLEIRVKVSDYVQDRIRSLR--VAEPGRYQNIACLRSNAMKYLPNFFRKGQLSKMFFLFPDPHFKKTKHKWRIISPTLLAEYAYTLRIGGLVYTNTDVEEVHEWIVQHFSDHPLFSRVTEEQLADDIIVGHLGTCTEEGKKVQRNGGKNFLAVFRRVEDPQT------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O77263-1", "uniprot_id": "TRMB_DROME", "id": "O77263-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "------------------MVATGGQAQDQGQNQEPDVLNPTSAVTGLPQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPGIQQ-------------------GQQVSFADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNIACLRTNAMKYLPNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKGGLLYTMTDVEDLHKWIVTHMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12009-1", "uniprot_id": "TRMB_YEAST", "id": "Q12009-1", "name": "tRNA (guanine-N(7)-)-methyltransferase", "aln": "MKAKPLSQDPGSKRYAYRINKEENRKELKHVKINESSLVQEGQKIDLPKKRYYRQRAHSNPFSDHQLEYPVSPQDMDWSKLYPYYKN-------------AENGQMTKKVTIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALRNNTASKHGFQNINVLRGNAMKFLPNFFEKGQLSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTITDVKDLHEWMVKHLEEHPLFERLSKEWEENDECVKIMRNATEEGKKVERKKGDKFVACFTRLPTPAIL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:************::** : **. *:::** :** :* :******:**::: *. **: * :*:****:*::** *** :** : :*** ** ****.***:* **** **** :******: *** ***. :**:**** *: **::** *** ::*.*: *:.:***:.::. * * . : .:*** ** *: *.:* * * *: ", "identical_positions": 114, "similar_positions": 55, "identity": "36.77%" }, { "cls_id": "homologset.agr.SGD:S000002361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C4-1", "uniprot_id": "RM10_RAT", "id": "P0C2C4-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MPFSVEVEVFFLLVEDKLGWLPTLQPVRHGSKAVTRHRRVMHFQRQKLMAITEYIPPRPAVSPRCLPPPPKPPKE--ESGLIRLLRRDIAAVFRDNRMIAVCQNVALSAEDKLLLRHQLRKHKIFIKVFPSQVLKPFLEDSKYQN-LLPLFVGHNLLLVSEEP---KVKEMVRILKSVP-FLPLLGGCIDDTILSRQGFVEYAKLPSLDRLQGELVGGLTHLTAQ-TRYLLQHQPVQLTSLLDQYVRQQHEGDCATSTEGKPHPPDPAPDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TBW2-1", "uniprot_id": "RM10_MOUSE", "id": "Q3TBW2-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAAAVAG-ILRGGLPPRAAWLPTLQTVRHGSKAVTRHWRVMHFQRQKLMAITEYIPPKPAINPRCLPPPPKPPKE--ESGLVRLLRQDIVAVFRDNRMIAVCQNVALSAEDKLLLRHQLRKHKIFIKVFPSQVLKPFLENSKYRN-LLPLFVGHNLLLVSEEP---KVKEMVRVLKSVP-FLPLLGGCVDDTILSRQGLVDYAKLPSLDQLQGQLVGGLTHLMAQ-TRYLLQHQPVQLTSLLDQYVKEQNEGDCATSANEKLHPPDPAPDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7H8-1", "uniprot_id": "RM10_HUMAN", "id": "Q7Z7H8-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAAAVAG-MLRGGLLPQAGRLPTLQTVRYGSKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQE--EIGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQN-LLPLFVGHNMLLVSEEP---KVKEMVRILRTVP-FLPLLGGCIDDTILSRQGFINYSKLPSLPLVQGELVGGLTCLTAQ-THSLLQHQPLQLTTLLDQYIREQREKDSVMSANGKPDP-DTVPDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJB7-1", "uniprot_id": "RM10_DANRE", "id": "Q5BJB7-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAATLCC-----RLLPKAGWVPLTQSVRHGSKAVTRHKKPVHFQKQKLLAVTEYIPPTLSAPPAALAPRVKKTGE--ESSLAVMLRKDLENLFQEYKMIAVAQNNAISAEDMIHLKHRLKKHAINVKFFPNQVTRSFLNSSIYGN-MSPLIFGETVLLASKEP---KVKEMLQALRHNP-QIVLLGACIENTLFSYQGILSYSKLPSIAIIRGELVSGLTMMTSK-TVSMLHHHPAHLSALLQQYVKQQSSADTDKDASIQEAAA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPL3-1", "uniprot_id": "RM10_DROME", "id": "Q9VPL3-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MATLIQR-----SLSLAKSSTPALQFLRFRGKINIQRPKAPHYERARVVAVTQPKYPELPKAKSCFKTRAERTQQQQENPYNEIIAREVRNWLDHSRLVAFFHLSSITADDIFRVRVQLHKQNLHLKSYGSKIIEQAVKNTRYEA-IVPLFHSNHCIVFSPDPE--KTAALLRIVRRVP-QMVLLGGIVEETMLSRNQLVAYAQMPGLHAVQAQLVQTLSQAPGH-LIQQLQAHQNSFVQVLDVHAKNQMNEETPKST-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36521-1", "uniprot_id": "RM11_YEAST", "id": "P36521-1", "name": "Large ribosomal subunit protein uL10m", "aln": "----------MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASE---QPSRKTVKPLDSRKTFLIDTYKHLME--NSSMIFFVHYNNLSKTEDH---HFRFKIKQTGGKLTKVRNNLFEVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSAQDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSNALYLTLKSHNDNQKPKEDVESTTDAESKGSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . : : :. : . : : :: : . . :. . :: .* : : . . :. : : **: . : :. :. ::: :: : ::*. ::: ::. : : : :* ::.:** * . *. : *. : :* : .: ", "identical_positions": 12, "similar_positions": 70, "identity": "4.43%" }, { "cls_id": "homologset.agr.SGD:S000002362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCV6-1", "uniprot_id": "DELE1_MOUSE", "id": "Q9DCV6-1", "name": "DAP3-binding cell death enhancer 1", "aln": "-----------------------MWRLTGILGRALPRLLGPGFRGITPKPTSSDG--------------SQTTSPTLPLTRLSFDRSGSHGS--KRSRDPKCCGWKDAFHWMSAHVSPNTLRDAISWGTLAVLALHLARQIHFHAPLVAGPQPAER-SWHSPLYRFLSSS--WWHPHSSLRRHVLPRSDCPAPRNTGLREPRQGQEDHPSAPSQCLPSDSSLRSGLLNLPEEEPSDFDFLHASRDFAS------------------------------QAKAAEAHPPGGKNEQDKAKALPLEEAVTSIQQLFQLSVAITFNFLG------------TENIKTGDYTAAFSYFQKAADRGYSKAQYNVGLCLEHGRGTP---------RDLSKAILFYHLAAVQG-HSLAQYRYARCLLQSPGSLSDPERERAVSLLKQAADSG---------------LTEAQAFLGVLFTKEPHLDEQRAVKYLWLAASNGDS-QSRFHLGICYEKG-LGAQRNLGEAVKCYQQAAAMGNEPARERLRTLFNVEAAG--PSHLATTGLKSFS---SPSLCSLNTLLAGASGLPHASSTGNLGLLCRSGHLGASHGAPSRTIP----SLERSLVRLGFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60924-1", "uniprot_id": "DELE1_RAT", "id": "P60924-1", "name": "DAP3-binding cell death enhancer 1", "aln": "-----------------------MWRLTGILGRALPRLLGPGFRGITPKPTSSDG--------------PQTTSTTLPLPRVNFDRSGSHGS--KRNRDPKCCGWKEAFHWMSAHVSPNTLRDAVSWGTLAVLALHLARQIHFHAPLVAGPQSAERCSWHSPLYRFLSSS--WWHPHSSLRRHVLPSPDCPAPRNTGLREPRLGQE-EPAARSQGLPSDSSLKPGLLNLPEEEPSDFGFLNASRDFTS------------------------------QAKAAEAGPPGGKNEQDKPKALPLEEAVTSIQQLFQLSVAIAFNFLG------------TENIKTGDYTAAFSYFQKAADRGYSKAQYNVGLCLEHGRGTP---------RDLSKAVLFYHLAAVQG-HSLAQYRYARCLLQSPGSMSDPERQRAVSLLKQAADSG---------------LTEAQAFLGVLFTKEPHLDEQKAVKYFWLAASNGDS-QSRFHLGICYEKG-LGVQRNLGEAVKCYQKSAAMGNEPAQERLRTLFNVEAAG--PSHLA-IGLKSFS---SPSLCSLNTFLAGASGLPHASSTGNLGLLCRSGHLGTSHGAPSRAMP----SLERSLVRLGFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14154-1", "uniprot_id": "DELE1_HUMAN", "id": "Q14154-1", "name": "DAP3-binding cell death enhancer 1", "aln": "-----------------------MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDG--------------PQTTSSTLLVPVPNLDRSGPHGP--GTSGGPRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSWHSPLDRFFSSP--LWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQE-EASAQPRNFSHNSLRGARPQDPSEEGPGDFGFLHASSSIES------------------------------EAKPAQPQPTGEK-EQDKSKTLSLEEAVTSIQQLFQLSVSIAFNFLG------------TENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTP---------RDISKAVLYYQLAASQG-HSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSG---------------LREAQAFLGVLFTKEPYLDEQRAVKYLWLAANNGDS-QSRYHLGICYEKG-LGVQRNLGEALRCYQQSAALGNEAAQERLRALFSMGAAAPGPSDLTVTGLKSFS---SPSLCSLNTLLAGTSRLPHASSTGNLGLLCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07622-1", "uniprot_id": "ACK1_YEAST", "id": "Q07622-1", "name": "Activator of C kinase protein 1", "aln": "MVNQGQPQPNLYDKHINMFPPARARESSHKLGNANSDRHGLPAQNIVPAPYPVDDSIVELTPAIPFTSPSSSSSLSLPLSALNFTDGNADGGQLGTPVTINSNNGMDIFNSKPTGEIGYANNGTNSTGSRYELPFNFSSTKESLGSPAVQDASISSGNRISESVRDNSAPPPYEESESRILQEKVYRTEEKAPIRPLNNNPVPPQKINQPPTGSAKTDDNGSSGGEDKLSSYSPEALAFYQVYKKTITDSSKFTPEIQMQWCETLLTYAFNEDFISQYNINAEKLKRSLKPEEMLKNQKVILEHSFKVLTKLITLKWPPAMYLMGTLYSHQPYLPIKNKNIVIKNDEKALEYYCKAAKLNNSDACYRAGVCFEYQRGTSSLDPSPTKEQCIKKAFQYYQHGAEVCSNSACMYKLGMSHLYG-LNMQKTDVLLAIKWFDKAAQKGDSPQTLYELGKIYEFSVLPPEIQNLLFANGIRKDSQLAIKYYQQCAKDFEYPLAQWKLGNCYEFGDLGLPVVAKKSIYWYSKAAAAQPKGNPMAMLSLSGWYLTG-APNILKPNNKEAFNWALKSSKCSDGKLARTEFALGFYYEKG-VGCEVDLDLAKQYYQRAARMGFRKAVDALRSLTN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **.* . * :.* . . *. ..::* :* :. .: ....* .. . : *: .: : .: * *: *.:::: . .. . . . * * *:. .. * : :. : .: ** .. .:* *: . .. . :. . .. * : * :. . : : :. : . * * : : **.:.. : :*: *. . :: ::* .:*: : *:.*: *** . *.* *..*:* *: ***. : :.**. :*: .* :* . *: . . * . . ..: *:. :.:**:.* . : .:**:: *.* *:** .*.: : ::::** *** * ** ::: *.::** : : :* . :. *. * . ::*. ..* ** ..: * . ..* :* . .:* **:.. ", "identical_positions": 88, "similar_positions": 179, "identity": "13.97%" }, { "cls_id": "homologset.agr.SGD:S000002363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0T0-1", "uniprot_id": "RTN1_MOUSE", "id": "Q8K0T0-1", "name": "Reticulon-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPPDLQDEPLSLGSPGSQWFGGRGDGEDEATAVMGARPAQQDGEPAWGSGAGAGVTSSRELCSGPARSPPVAMETASTGMAAVPDALDHSPSSTLKDGEGACYTSLISDVCYPPREDSAYFTGILQKENGHITTSESPEEPETPGPSLPEVPGMEPQG------LLSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPQEAKGQE-------------------------------------------------EQHPGLEDKDLDFKDKDTEVSTKAEGVRAPNQPAPVEGKLIKDHLFEESTFAPYIDELSDEQHRVSLVTAPVKITLTEIEPPLMTATQETIPEKQDLCLKPSPDTVPTVTVSEPEDD------------SPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQVADKPKTKTRSGLPTIPSPLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELI----IESCDASSASEESPKREQDSPPMKPGALDAIREETGSRATEERAPSHQGPVEPDPMLSFAPAAALQSRPEPSSGDGASVPEPPRSQQQKPEEEAV--------SSSQSPTATEIPGPLGSGLMPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDE-GHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64548-1", "uniprot_id": "RTN1_RAT", "id": "Q64548-1", "name": "Reticulon-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPPDLQDEPLSPANPGSQLFGGRGEGEE--ATPKGARPAQQDGEPAWGSGAGAGVVSSRGLCSGPARSPPVAMETASTGVAAVPDALDHSSSPTLKDGEGACYTSLISDICYPPREDSAYFTGILQKENGHITTSESPEELGTPGPSLPEVPGTEPHG------LLSSDSGIEMTPAESTEVNKILADPLDQMKAEACKYIDITRPQEAKGQE-------------------------------------------------EQSPGLEDKDLDFKDKDSEVSTKPEGVHAPNQPSPVEGKLIKDNLFEESTFAPYIDELSDEQHRMSLVTAPVKITLTEIGPPVMTATHETIPEKQDLCLKPSPDTVPTVTVSEPEDD------------SPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQAADRPKVKARSGLPTIPSSLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELI----IESCDASSASEESPKREQDSPPMKPGVLDAIREETSSRATEERAPSHQGPVEPDPILSFTP-VTLQSRPEPSSGDGAPVPEPPKSQQQKPEEEAV--------SSSQSPAATEIPGPLGSDLVPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDE-GHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16799-1", "uniprot_id": "RTN1_HUMAN", "id": "Q16799-1", "name": "Reticulon-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPGDPQDELLPLAGPGSQWLRHRGEGENEAVTPKGATPAPQAGEPSPGLGARAREAASREAGSGPARQSPVAMETASTGVAGVSSAMDHTFSTTSKDGEGSCYTSLISDICYPPQEDSTYFTGILQKENGHVTISESPEELGTPGPSLPDVPGIESRG------LFSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPEEVKHQE-------------------------------------------------QHHPELEDKDLDFKNKDTDISIKPEGVREPDKPAPVEGKIIKDHLLEESTFAPYIDDLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKPSPDTVPTVTVSEPEDD------------SPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKGLSYETAENPRPVGQLADRPEVKARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGGPPPSPASPSIQYSILREEREAELDSELI----IESCDASSASEESPKREQDSPPMKPSALDAIREETGVRA-EERAPSRRGLAEPGSFLDYPS-TEPQPGPELPPGDGALEPETP-MLPRKPEEDS---------SSNQSPAATKGPGPLGPGAPPPLLFLNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDE-GHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHAE------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70622-1", "uniprot_id": "RTN2_MOUSE", "id": "O70622-1", "name": "Reticulon-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQVLPVFAHCKEAP-------STASSTPDSTEGGNDDSDFRELHTAREFSEDEEE--------ETTSQD-------------------------------------------------WGTPR----ELTFS------------------------------------YIAFDGVVGSGGRRDSVVRRPR---------PQGRSVSEPRDPPQQSGLGDSLESIPSLSQS------------------PEPGRRGDPDPVPPAERPLEELRLRLDQLGWVVRSAGSGEDSATSSSTPLENEEP-----------------DGLEASEAGEETNLELRLAQSLHLQLEVLT----------PQLSPSSGTPQAHTPSPQR---------------SQDSNSGPDDEPLLNVVEEHWRLLEQEPITAQCLDSTDQSEFMLEPLLL----------------------------------------------------------------------------------VADLLYWKDTRTSGAVFTGLMASLLCLLHFSIVSVAAHLALLGLCATISLRVYRKVLQAVHRGDG-TNPFQAYLDMDLTLTREQTERLSQQIASHVVSTATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPGTGTLAP-TASVSGSKAKAE-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6WN19-1", "uniprot_id": "RTN2_RAT", "id": "Q6WN19-1", "name": "Reticulon-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQVLPVFAHCKEAP-------STASSTPDSTEGGNDDSDFRELHTAREFSEDEEE--------ETTSQD-------------------------------------------------WGTPR----ELTFS------------------------------------YIAFDGVVGSGGRRDSVVRRPR---------PQGRSVSEPRDPPPQPSLGDSLESIPSLSQS------------------PEPGRRGDPDTVPPAERPLEELRLRLDQLGWAVRSAGSGEDSATSSSTPLENEEP-----------------DGLEASEAG-ETNLELRLAQPLHLQFEGLT----------PQLSPSSGIPQAHTPSPQR---------------SQDLNTGPD-EPLPNGEGEHWRLLEQEPITAQCLNSTDQSEFTLEPLLL----------------------------------------------------------------------------------VADLLYWKDTRTSGAIFTGLMASLLCLLHFSIVSVAAHLALLGLCATISLRVYRKVLQAVHRGDG-TNPFQAYLDMDLTLTREQTERLSQQIASHVVSTATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLVTSQLSHIKAKIRAKIPGTGTLAP-AASVSGSKAKAE-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75298-1", "uniprot_id": "RTN2_HUMAN", "id": "O75298-1", "name": "Reticulon-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQVLPVFAHCKEAP-------STASSTPDSTEGGNDDSDFRELHTAREFSEEDEE--------ETTSQD-------------------------------------------------WGTPR----ELTFS------------------------------------YIAFDGVVGSGGRRDSTARRPR---------PQGRSVSEPRDQHPQPSLGDSLESIPSLSQS------------------PEPGRRGDPDTAPPSERPLEDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQE--------------PNRLETGEAGEELDLRLRLAQPS--SPEVLT----------PQLSPGSGTPQAGTPSPSR---------------SRDSNSGPE-EPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFTVEPRLLGTAMEWLKTS-LLLAVYKTVPILELSPPLWTAIGWVQRGPTPPT--------PVLRVLLKWAKSPRSSGVPSLSLGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAVHRGDG-ANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPGTGALASAAAAVSGSKAKAE-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4B6-1", "uniprot_id": "A0A8M2B4B6_DANRE", "id": "A0A8M2B4B6-1", "name": "Reticulon", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQVLG-FSHCKEFGT----VNSTPDSTPPCSDGGNEESDFPELQTAREWSDEDDEGLEDDDACLSSSSV-------------------------------------------------WGTPRQNSFELTFS------------------------------------YIAFSESDGTS-RRDSGRRRTG---------PRSG--------------RGSLHRTDTLETQ------------------PPPD--------SPAVEWDPHAFLTLDGEGDVEEESQMWTVETQSLETLQDKDTG--------------------TWDTAEKISGIQSYNLTCSHQEEQITV----------PQLPASDPAVATETTATLQ---------------TAEASHTMPPSVGPNTQE--------EQTCKQWFSSLSLSEGPTIHIQIA---------------------------------------------------------------------------------VMDLVYWKDMERTGMVLTGLVVALLSLFQLSIITVVSTLSLAILCFTISVRIYYKLLHVLQLGDG-VHPFQSYLDLDISLSGEEAEHCLQRAIVLSCSALETLRNLIFVGNLFSSLKFWLLMYVVTFLGNLCNGLTLIIIGVIAVFSVPLFYTRHQDKVDSCIVAVQAQIDNIKDFFYRLTQGGGPPPD--PTPGGAKPKAH-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95197-1", "uniprot_id": "RTN3_HUMAN", "id": "O95197-1", "name": "Reticulon-3", "aln": "MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVSLFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEE-GHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALGGDTGNVSGGAQDDNAHTEHYFANEQKKLDFGDAQEFVQRLAADAKDAKLDLDTKFAQKTDDFEDFLRDAGKEVKQGISGLTTDFMNAERGFSAPLAPFS-------ETVAQAPVIPAQAPAVPDHAPAVPAPVAPAPAVPAPLPVEEDLLGSFTD------------------------------------------------QPSAPLQAFQPTAP-----------------------------------STANFYDDEEDDFLGKPTTAAPAAP-----VAPLTKANQDSDTESPSVSYTPSPAKKPIVDALKD---------------QDNEKFISSEDLASDFKEEPRSAPTPAPAPAPILDAAPAVAPAPVAVPVSVPVAKP----------------------QPVPVAVPVTTALITDLDDEEVVFKP--------TVQEAPKAPTIAAPVVEPKPEP-------------PKPKVEPAKPKVVPVAPVESTQPQPKIASVEEIFCKYGLDAWFKPERLHP--------------------------------------------------------------------------------QVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNE-GHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIB7-1", "uniprot_id": "Q9VIB7_DROME", "id": "Q9VIB7-1", "name": "Reticulon-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTDTLIKAKDSSQIFMD--------------------------------------------------------------------------------------LKNLLLWRNSRKTLIVFTGILLLLLDVMVHSVISVISMVGITVLIAAIGHRLLVQFWSIWKKDENKDQILRFYPHPKIEIPREETLYLAGKAVSHINLILNRMIELLLVEKWEDSLKFLVLLCGINLLGDCFNGLTLLIFGHLFIFTVPKLYESYKPFVDVQIRKFRKCKIDKSNVEKPICIQKECPPESAYEGQESKEGKVLYEPCDNEPLRNLLELHKGCRCPDCEHRYLPVEAR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12443-1", "uniprot_id": "RTN2_YEAST", "id": "Q12443-1", "name": "Reticulon-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRNTTTNKNANLNNSRNANAPGEAGHQNKTG-----------------------------------------------------------------------------------------------------------------LIYWTNPSKSGASFAATLVSLLILR----NVNVISVLLKIGYMVLFTSFAVELSTKVLFDKG--------------------------VVSRFGMQESPDLVGVLKPHIDRELDRLPALEDRIRKLVFAHR--------------------------TRNNFTIGVSLYFLHGLFAIFSMNT----------VLIMTTIFLYTVPLIYDRK-------------------------QARIDRAIDRMKDLVIHRFHKNYNKVVEKTEPYIDKIIPP---------------------------------------------------------------------------------QTDEGSYSTSISNENKSSTSQRNKSGLSSSEFDNMNDTSASKSGKDSYSTSQYNRAEYPVSQNEN----IGTLKSGKQEIPTEKDFNNRHENFSKPDVKTYDPR----TVDIEEELAAHQRELEQNLKDGDYNLVGSKEIPDPITVPAPTRHTTKPAESQSIPIKNNETLHKTTHGLKQKLQHA-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : .. .: : . : : . :. * . . ..: . . * : : .. * : : ", "identical_positions": 3, "similar_positions": 28, "identity": "0.28%" }, { "cls_id": "homologset.agr.SGD:S000002364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19356-1", "uniprot_id": "HEM3_RAT", "id": "P19356-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGGAATTAEENGSMMRVIRVGTRKSQLARIQTDTVVAMLKTLYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDEQL-EFSAIILAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMK------DGQ---LYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22907-1", "uniprot_id": "HEM3_MOUSE", "id": "P22907-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGGAATTAEENGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDELQ-EFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMK------DGQ---LYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08397-1", "uniprot_id": "HEM3_HUMAN", "id": "P08397-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNE----VDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQ-EFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMK------DGQ---LYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDAH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3W7-1", "uniprot_id": "A0A8M2B3W7_DANRE", "id": "A0A8M2B3W7-1", "name": "Porphobilinogen deaminase", "aln": "-MADGPYKYARDSDGRVSRVIRVGTRKSQLARIQTDSVVEKLKELYPDVLFEIVAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDLPTVLPGGFTIGAVLKRENPHDAVVLHPKNKGKRLDSLSNKSVIGTSSLRRAAQLKKRFPHLEFKDIRGNLNTRLKKLDENN-DFSAIILAAAGLKRMGWENRISQILGPEDCMYAVGQGALAVEVRARDLDILEMVSVLNDSDTALSCIAERAFLKHLEGGCSVPVAVHSEVK------NSQ---LYLTGAVYSLDGSDSLKETMQTSFNPDTQAEEQEKV----------------------------------------------------------------------------------------------DEKVQRLGITALKVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAAQDAAMKLGVDLGNLLLSKGAKEILTVARQLNDAR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0G4-1", "uniprot_id": "Q9W0G4_DROME", "id": "Q9W0G4-1", "name": "hydroxymethylbilane synthase", "aln": "-------------MSAQEKVIRVGSRKSELALIQTKHVIGRLQKLYPKQKFEIHTMSTFGDRVLNVSLPKIGEKSLFTRDLEDALRNGG----VDFVVHSLKDLPTALPTGMAIGAVLEREDARDALVLRENFKGHTIASLPKGSVIGTSSLRRTAQIRRMYPHLTVCDIRGNLNTRLAKLDAADSKFSGIILAQAGLVRMGWMSRISQVLEPTDLLYAVGQGALAVECRANDDQVLAMLQKLMCLNTTCRILAERSFLKTLGGGCSAPVAVWSNLKGEPLNGNSQEVGLSLTGAVWSLDGAIEIRNHLACALNEQKLEGDQRKRGAQEATSQLQEETSSSCDSPPATKRARNGNDSSGSDSNSSSPRQQGSPPVICEDAAACAALSGYTVDQLSDLASHCPVLSNNNAVGPTGVSGGGDADTNNVNTTPRQCPLRLVGGQEVMGQCPVPHNQAMVPAKCPVAHADSGDSFSAKSGSGGESATTAHCPLQMPVGQDFMGECPYVNNDVKVSFAQAGKCPVTGGVAGASASILPTPPSSRASNASSAGDEVDNVATSSKCPFAAMHQGSGLEAPAKDNGNAATAKCPFLQKTVQMFDYADEEQPTPQHSVLIEDVENLFCGLYQHACHSRGIYEKANQLGKTLAEDLIKRGALDVMKVAQAEIHGKVASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28789-1", "uniprot_id": "HEM3_YEAST", "id": "P28789-1", "name": "Porphobilinogen deaminase", "aln": "-------------MGP--ETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYN-------EETKKLLLKAIVVDVEGTEAVEDEIEMLIEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEDSMACGKILAERMIADGAKKILDEIN-LDRIK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:::* ***:** **:. *: :: ** :: ::.* **:: .* .:* *:*:*::**. * :. :*::******:** ** *: :*.: :* :. *.:*: : : *.. . :****:** **::: :*** . .:***::*** *** :. *:** *** *** .*: * : . :*******.:* * * .:: :: : :: ::**:::: * ****.*:.* : : : * *.. * .::*: :.: : :. : * *.. :: ** .:: . : ", "identical_positions": 97, "similar_positions": 111, "identity": "14.5%" }, { "cls_id": "homologset.agr.SGD:S000002365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXS0-1", "uniprot_id": "NCLX_RAT", "id": "Q6AXS0-1", "name": "Mitochondrial sodium/calcium exchanger protein", "aln": "------------------------------------------------------------------------MAGRWLDPLWAPGFLCVALILETASGAGDLSTKAHGHIQFSARGVNQTAMADCRAVCSLNTSDRCD-FVKRNPDCHSEGGYLDYLKGIFCYFPPN---LLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTSLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVTTVVAGG-ITILRPFMAASRPFLRDITFYMVAVFLT-FTALYLGRITLVWALG---YLGLYVFYVVT-----VIICTWVYQRQRSRSLVHSISETP-----------ELLTDSEEDQMSSNTN--------------------------------------SYDYGEEYRPLLLGEETTG----QILLQALNPLDYRKWRTQSISCKLLKVAKLPVEFLLLLTVPVVDPDKDDR---------------NWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWA------VVVIVG--------------------TALASVTFFATSNSEPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIVRSHASEVKLEPDGLLVWVLASALGLSLVFSLVSVPLQCFQLSKAYGLCLLLFYICFIVVVLLTEFGVIHLKAD-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925Q3-1", "uniprot_id": "NCLX_MOUSE", "id": "Q925Q3-1", "name": "Mitochondrial sodium/calcium exchanger protein", "aln": "------------------------------------------------------------------------MASRWLALLWAPVFLCVALILETASGTGDPSTKAHGHIQFSAGSVNQTAMADCRAVCGLNTSDRCD-FVRRNPDCRSEAGYLDYLEGIFCYFPPN---LLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVTTVVAGG-ITILHPFMAASRPFLRDIAFYMVAVFLT-FTALYLGRITLTWALG---YLGLYVFYVVT-----VIICTWVYQRQRSRSLVHSISETP-----------ELLSESEEDQMSSNTN--------------------------------------SYDYGDEYRPLLLGRETTV----QILIQALNPLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDR---------------NWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWA------VVVIVG--------------------TALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVLLTEFGVIHLKKA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6J4K2-1", "uniprot_id": "NCLX_HUMAN", "id": "Q6J4K2-1", "name": "Mitochondrial sodium/calcium exchanger protein", "aln": "------------------------------------------------------------------------MAGRRLNLRWALSVLCVLLMAETVSGTRGSSTGAHISPQFPASGVNQTPVVDCRKVCGLNVSDRCD-FIRTNPDCHSDGGYLDYLEGIFCHFPPS---LLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGLALGALFGAGVLVTTVVAGG-ITILHPFMAASRPFFRDIVFYMVAVFLT-FLMLFRGRVTLAWALG---YLGLYVFYVVT-----VILCTWIYQRQRRGSLFCPMPVTP-----------EILSDSEEDRVSSNTN--------------------------------------SYDYGDEYRPLFFYQETTA----QILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQ---------------NWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWV------VVVIAG--------------------TALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHT-EVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGVIHLKSM-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7I1-1", "uniprot_id": "A1Z7I1_DROME", "id": "A1Z7I1-1", "name": "Sodium/calcium exchanger membrane region domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MSGRTKRTKFN-----ITELDHEFHYFIKNMSCRAVMRLPYNYRCR-MATQVSDCKRIINFFNYFRMMYCSIDIDDKATEVLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPVR---ADAPIFTITVGNTLAIILLSGGT-VCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLGEG---IVLFLIYVVYVAINIADLALLRYYIRKLRRELDYLEGLTPPPITEIN--AKIRKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMT------SSGYFVTPIPERRSEHVDYELNRTALHDSENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKH---------------GWSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFS------ISMW---SPC--------------LTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMSLAFIFNHRVREVGANSWVYGDLGDNCYL-FLVITIVTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVEWDVVHEFSRDQHFKPI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7I2-1", "uniprot_id": "A1Z7I2_DROME", "id": "A1Z7I2-1", "name": "Sodium/calcium exchanger membrane region domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MSLKYLINTSP-----YSFLNES--DFMQNVSCLAVMHFSYLHRCE-MATKIDDCKYITNFFNYYVMMYCSFKIDNKITEIVVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVNLSPVR---MEGLTFNIAMANALTIICLSGGA-VCFIRPFRMNGHSIFRDLLFLLLIIELVRFFMNDTALAPWIKG---AILLSIYPIYLLINIVDLILLRYAIRKLRADIEVLRQSPSSREHDLILTEKIVRLNNLQQDDEIQILESKLYRKR--TYN-------------AGFFVTPKPLIHHKEVDVETNRRILHSKANPKNLFLFSEFLQAINPIDSEGWYLSGTCARILQILKAPVTLMLHLVVPLVDYQLVKH---------------GWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFR------MAIW---SLL--------------VTMPLAIVVFLHSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQ-VVLYGDDGVTIYI-FLVITITTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIELQWVHGFQDNIQIRPTA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAJ4-1", "uniprot_id": "A1ZAJ4_DROME", "id": "A1ZAJ4-1", "name": "Sodium/calcium exchanger membrane region domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MPAIDTKTTKSDVFTVKNALDAEFDNFWKTVSCFAANNFPFEERCE-FVQKAEDCNSSTNVIPYMRLLACDLKCINQFQEMIFIALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLASVE---RHVPVFANNLSSALFVITISGGL-IFYISPFKMNSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVLLVYISYIIINVADVYLLQKTIASTRTKMQKLLDEKQTPEIALKLQDLERKLEYYSQDTRVEILEKSSSISIT----------------RIRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKH---------------GWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQN------TLIYGASSFV--------------LTVPFAVFILFHARTDVPPSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFTIVVTGNTVAYVRSLVGNRSE--HHMEEYGEIAFI-FLNMALFTILLWSTTLGFFARRSMGLYSIGLYVVYLLFVTLVHEEVIHSFSDDIQVKSAFGDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8H3-1", "uniprot_id": "A1Z8H3_DROME", "id": "A1Z8H3-1", "name": "Sodium/calcium exchanger membrane region domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------MVHDLLESQKCK-FVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQ--TSKHSFLSCMSQAMFLHIFVAGL-VILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAALP---SAFIFVGYVVVAIVDQHLLIARIQKMEQRQLNVAEA--------------LQLEELKPQKEMPLKRQ------------------------------------------EIDRPSIGHGSRNKR--IFRQFWNTVAEFDKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQY---------------GWSKLLFNIQVVLVPTYIAYIIVRGYSIAG-----LAVYM------IALILM--------------------IPVATLIFFLTRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSFVNAPGNIFPTEGGFGETVCI-FLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVGVLILLEKGVIHAYGV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12424-1", "uniprot_id": "YD206_YEAST", "id": "Q12424-1", "name": "Putative cation exchanger YDL206W", "aln": "MHKPLRWLITIAFYVSNVILIGYSLSSNGSISEFYLHSVVLIECFSLLGVVTSDCLTPSLSYISSNIFHISDRVSGMTLLALGNALPDITSTYQSMKSGVTSLAIGELFGGIFFLLTVVIGLMGCVATIQFQHDKSIETYTEESFDQNLSYDRSNYILDVGIFTFMLLVSGTFLADGRLYFWECIVMVLTYCCCAVYLIKSYKYPCEINDALEREVEIKKTVLANNHITVPNRFTLTTTSDITSTDDGIRYVRPLGDTQIDEDN-AISLDPTRLPSKSLDNISRFNQGIPERRDLIRRRIRGYLRSHYHG---WVRMTLQDLLNIWEKQNLFNNTVKSLSLPSDDTHLFTKASLDEEGRPLIRKRMNSLQPKDFYKYLSLRNGENSNALDTAISAPQNEYQTYYNEPTSLFLTVPQKKTSKKSLSCDRIPNLVRSNNIILNDEATRTQESTNALNSISDVIDNSLLQYERDDIILDRTLSLCSTKSRTAWHSFQLYNYLTDVSLEIGFFEFLSLLVTTPVSIILYLSIPSEISQTDHDLPLSYLQN------IQLIASPIILNQLITNNFSFWLLILSLVIAILLYFKTRTIPNKFNSDIIFTVAFLLSLACLSKAVHIIVVTLTHWINVFNISETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIMLGDKTGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKISIALLTLYIVVTCISVFLEVHQV----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8N7T746-1", "uniprot_id": "A0A8N7T746_DANRE", "id": "A0A8N7T746-1", "name": "", "aln": "-------------------------------------------------MDGDACVRVWTRPLQVMLQQKKIKARRKKRKELFGGQMCFMGLLLLAVSGLSSLAENSGYGIPSLSAEDSKKWESRRLLQDFDIDSNYTDEVQLGPNADKNCTPPGIHEFPDDIFTQQE--RLEGAVALHVLCAMYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVTWWESLIL----IVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDIDDGCDATVVLLKKANFHRKPSVLMVDELLS-------------------------AYPHQLTFSEAGMRIMITSHFSPRTRLTMASRMLITERQRLINSRFSNGDSEVTVKMPGKRGVENGLAGPDRGLNGRKGGHHDD----------DRGGAEAGTDTENENEDNENNENDEEEEEEDENEGPYVPFRCPGGGIN-------------------KLKWLLAWPLSMLLFFTVPNSANPRWERWYMVS-FISSTIWIAFFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAINYGSTIHLNSK-GLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIEFNIFTFVNLPTCREE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : . . . .. . . . . . . : : : :. : . . . : . . . .: . : : : : : : * .: .. * :*: :.. . . . : : . ", "identical_positions": 3, "similar_positions": 53, "identity": "0.39%" }, { "cls_id": "homologset.agr.SGD:S000002366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K222-1", "uniprot_id": "A0A0G2K222_RAT", "id": "A0A0G2K222-1", "name": "mRNA export factor GLE1", "aln": "MKFFIK------PSGGRCWKTLRALRDSSRVSLHLEAEGLR---SSLEGGSSLAKLSSDLAWVVDDIPPDSSGHSADEAPPS-DNSPSSGSASGLQGPS-LLESPRTSTPQSPS-PSRPSGTQSTRESPFTDPIALQ------------------CSPAIGVEACLRMYQLASRRRAAEGLRRRQEEQERKVRAFSEMACQQLERFDKLREQKLQKDFRDFRDMMEKGRREALGRQRKLRAEHGLRAKLLALKLGEAEQQQRQKQAEQERLPVEEGQVSVRSLYTVQEEVLRLNRQLEASVQQHRDLLNVDLSAFQSRGTQLCGFISGLLPTTLDTGYPTAENQAGAEGALQEMRDLLFHLEQEISRATEVKEE---EEAHIKGQESQGPQGPRAPAWTSAPSPSPEGTQEKEDPQLRVQDG-TMHWYQRLQDASAKCELAFEDLSSSKDSQDRRIKMDLQKAATIPVSQISSSAGSKLKEVFDKLHSLLSGQPVQSGGRPVSVSLHPQGLDFVQYKVAEKLVKQGESEVASHPEAAFPIAAVASGIWMLHPRVGDLILAQLHRQCPYSVPFHPAFKEGMALEDYGRMLGYRVTD-SKVEEQDHFLKRMSGMIRFYAAIIQLQWPYG-DRQEAHPHGLQHGWRWLAQVLN--LEPLPHVTATLLFDFLEVCGNALVKQYQVQFWKLVLVIREDYLPRIEAITSSGQMGSVVRLQQFLDKCLQRREIPVPRGFLTPSFWNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M6G0-1", "uniprot_id": "F1M6G0_RAT", "id": "F1M6G0-1", "name": "mRNA export factor GLE1", "aln": "MKFSLSYTAKFVPSGGRCWKTLRALRDSSRGSLHLQAKGLR---SSREGGRSLAKLSSDLGWVVDDIPPDSSGHSADEAPPW-DNSPSSGSASGLQGPS-LLESPRTSTPQSPS-PSRASGTQSTRESLFTDPMALQ------------------CSRAIGVEACLRMYQLASRRRAAEGLRWWQEEQEKKVRALSEMVCQQLERFDQLREQKLQKDFRDFQDRMEKGRREALGRQRKLRAEQGLRAKLLALKLGEVEQQQRQKQAEQEPISLEEGQVPVLGLCTLQEEVLRLNRQLEASVQQHRDLLNVDLSAFQSRGTQLCAFISGLLPTTLDTGYPTAENQAEAEGALQEMRDLLFHLEQEISRATEMKEE---EEARIKQQESQGPNHLRGPAWTSAPQPKPSRDSGEKDPHLQVQDRKTTQWYQRLQDASAKCELAFEDLSSSKDSQDRRIKMDLQKAATIPVSQISSSAGSKLKEVFDKLHSLLSGQPVQSGGRPVSVSLHPQGLDFVQYKVAEKLVKQGESEVASHPEAAFPIAAVASGIWMLHPRVGDLILAQLHRQCPYSVPFHPAFKEGMALEDYGRMLGYPVTH-SKVEEQDHFLKRMSGMIRFYAAIIQLQWPYG-DRQEAHPHGLQHGWRWLAQVLN--LEPLPHVTATLLFDFLEVCGNALVKQYQVQFWKLVLVIREDYLPRIEAITSSGQMGSLVRLQQFLDKCLQRREIPVPRGFLTASFWNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R322-1", "uniprot_id": "GLE1_MOUSE", "id": "Q8R322-1", "name": "mRNA export factor GLE1", "aln": "-----------MPSDGRCWETLRALRNTSKGRLRYDREWLLRYEDVLEECMSLPKLSSYSGWVVDHILPNTSGHTQESAPSS-DNSPSSGSASGLYQSS-LLKSPVRSSPQSPS-PSSPNGTQSTHESPFTEPIAPQ------------------SSRAIKVEGCIRMYELAHRMRGTEGLRQWQEEQERKVRALSEMASEQLKRFDELKELKLHKEFQDLQEVMEKSTREALGHQEKLKEEHRHRAKILNLKLREAEQQ-RVKQAEQEQLRKEEGQVRLRSLYSLQEEVLQLNQQLDAS-SQHKELLSVDLAAFQTRGNQLCGLISSIIRTTLESGYPTAENQAEAERALQEMRDLLSDLEQEITRASQVKKK-HEEEAKVKRQESQVQQGPAPPTQTSAPSPSPVGAQNE-DLQVKVQDS-TMQWYQQLQDASAKCVLAFEDLTSSKDSQTKKIKMDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGGRSVSVTLNPQGLDFVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWMLHPKVGDLILAHLHKKCPYSVPFYPAFKEGMALEDYQRMLGYQVTD-SKVEQQDNFLKRMSGMIRLYAAIIQLQWPYG-NRQEAHPHGLNHGWRWLAQVLN--MEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMILLIKEDYFPRIEAITSSGQMGSFIRLKQFLEKCLQRREIPVPRGFLTTSFWRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN4-1", "uniprot_id": "GLE1_RAT", "id": "Q4KLN4-1", "name": "mRNA export factor GLE1", "aln": "-----------MPSDGRCWETLRALRNSSKGRLRYDREWLLRYEDVLEECMSLPKLSSYSGWVVDHILPNTSHHTQENAPSS-DNSPSSGSASGLYQS--TLKSPVRSSPQSPS-PSTPSGTQSAHESPFTEPIALQ------------------SSRAIKVEGCIRMYELAHRMRGTEGLRQWQEEQERKVQALSEMASEQLKRFDELKELKLHKEFRDLQEVMEKSTREALGHQEKLKAEHRHRAKILNLKLREAEQQ-RVKQAEQEQLRKEEGQIRLRSLYTLQEEVLQLNQQLDAS-SQHKDLLNVDLAAFQTRGNQLCGLISGIIRTTLESGYPTAENQAEAERVLQEMRDLLSNLEQEITRASEMKKK-DEEEARVKLQESQVQQGPGAPTKTSAPSPSLVGTQSE-DLQVKVQDS-TMQWYQQLQDASAKCVLAFEDLTSSKDSQIKKIKMDLQKAATIPVSQISTIAGSKLKEVFDKIHSLLSGKPVQSGGRSVCVTLNPQGLDFVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWMLHPKVGDLILAHLHKKCPYSVPFYPAFKEGMPLEDYQRMLGYQVTD-SKVEQQDNFLKRMSGMIRLYAAIIQLQWPYG-SRQEAHPHGLNHGWRWLAQILN--MEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMILLIKEDYFPRIEAITSSGQMGSFIRLKQFLEKCLQRREIPVPKGFLTPSFWRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53GS7-1", "uniprot_id": "GLE1_HUMAN", "id": "Q53GS7-1", "name": "mRNA export factor GLE1", "aln": "-----------MPSEGRCWETLKALRSSDKGRLCYYRDWLLRREDVLEECMSLPKLSSYSGWVVEHVLP----HMQENQPLS-ETSPSSTSASALDQPSFVPKSPDASSAFSPASPATPNGTKGKDESQHTESMVLQ------------------SSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQERKVQALSEMASEQLKRFDEWKELKQHKEFQDLREVMEKSSREALGHQEKLKAEHRHRAKILNLKLREAEQQ-RVKQAEQERLRKEEGQIRLRALYALQEEMLQLSQQLDAS-EQHKALLKVDLAAFQTRGNQLCSLISGIIRASSESSYPTAESQAEAERALREMRDLLMNLGQEITRACEDKRRQDEEEAQVKLQEAQMQQGPEAHKEPPAPSQGPGGKQNE-DLQVKVQDI-TMQWYQQLQDASMQCVLTFEGLTNSKDSQAKKIKMDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGGRSVSVTLNPQGLDFVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWELHPRVGDLILAHLHKKCPYSVPFYPTFKEGMALEDYQRMLGYQVKD-SKVEQQDNFLKRMSGMIRLYAAIIQLRWPYG-NRQEIHPHGLNHGWRWLAQILN--MEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMLILIKEDYFPRIEAITSSGQMGSFIRLKQFLEKCLQHKDIPVPKGFLTSSFWRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRB1-1", "uniprot_id": "GLE1_DANRE", "id": "Q6DRB1-1", "name": "mRNA export factor GLE1", "aln": "-----------MPSENLRWETLEALKNSPKGKLKYSPDWVEKGEDVLAGCVEVPSLSPLSGQILKRMSPRMLLKNCSRSSSVRDTSPGLSEEAAVCRSAPISPRLKRSSCSLPAVSIQTEEEEEKEEEEKAEVVVEAPAVSPEASVSTPPAVSVLSPRATQISGCIRMCEQKHKAKAKMELSLRQEQQERLVATVANHESEQLKRFEEFMELKQRQEHQSIRDTNEKEAQESLGRQEKLREEHRHRMKILNLRLREMEQQ-RLREVELERQRQVEGRERHRAINAIQEEVLQLNRLLQPQ---QSTHAEVEHAPYITRGNQLCSQLSEVVPAAADDQFPSVEDLSVAERALQEMRSLVRSLQEAVSQAAERKKKKEQEEEEEKRRQEQLKAQQEEQKKSAALSAKEKAKKEG--LQTGADDS-TLKWYNSLQDLANQCAQAFDDLNKAKDTQTKKLKMELQKAATTPVSQIANSSGAPLKEAFEKIDKLLSRRPVTSAGKTVSTSQHPQGLEFASYRLAEKFVKQGEEEVASNHSAAFPIGAVASGIWELHPKIGDLILAHLHKKCPYAVPHYPPMESGTSVEDYQKILGYRVDE-GKVEGQDSFLKRMSGMIRLYAAIIQMRWPYS-SKQGLHLHGMNHGWRWMAQILN--MEPLADITATILFDFLEVCGNALMKQYRVQFWKLILIINEEYFPRYLCFASILHFTCIHWLQNIE-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4W1-1", "uniprot_id": "GLE1_DROME", "id": "Q9V4W1-1", "name": "mRNA export factor Gle1", "aln": "------------------------MDDMMRAMDCLNMAATLRNAALASATCTGRTLGEDREPIWVEGSRKTPEPPLPEESPAPEPNNEIPLLPKIDFEPNISCFPDLQAINASIVRRELEEEGKRCVRQQLKAIRDK-------------------QDAMRLSRETQQRKEERQRDQLQQKALRERNESLLIQKADQMTAAQLE-------AQQREQLALRQQIDQKLHKLALEGVSRCQRRFNQKYEGIAKILLSLNPETVKVCAAQNTQLKELGQKFEQLVSSVKMGNCEMQSQFLCSIIKAEEFCKSLDALELDIIKQLAEFSEQIQQQLKMEAAKKLEDERQRQQQQEEERQKLEEQQKLEEQEKLRKEK--EESAAKEKQQEAETAKADAANVPAPLEPKSQDVPPAATATSTSVHPDRLKFYNDILALYQSKVDAVKPLQTEES--LKQYRTGCQRAINLPLNAISAVSPQHLAQNFDKLYSFFAGQPTKVMNGTITINDHPLARDYCMLLMAKKFVSQTETAICSNPQAAFPFASVIITFWKLLPDFGKVFLAYMYKESPFLVPYVIPQQQGQTPEQYLKTIGYRLTDKNELEKPDIYLKRQTGLARLYAAVIISQGRKA-AGP-DECFELNEGWLWLAHMVH--VKPLPDISATLIMEILQTLGFELWRTYGKQFVKLLVYIQNIYMPQLAAYDEGGPK---TRLEMLLAKFLRERQIAQAVGVLPPGFW--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12315-1", "uniprot_id": "GLE1_YEAST", "id": "Q12315-1", "name": "mRNA export factor GLE1", "aln": "--------------------------------------MRFVFDEVFNSDTDSPEFEETCS----------TTSSTSSQCPTPEPSPAIKLPSFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAA--------------------SSIIVPHSTNMPLPRASHSSLLDNAKNSNATAPLLEAIEES-------------------------FQRKMQNLVLANQKEIQSIRENKRRVEEQRKRKEEEERKRKEAEEKAKREQE---------------------------------------------------------------LLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQN--EKERQLKKEHEAKLLQQKDKLGKAVTNFDKIS-----------------KMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQLTN-SNQQLFKIQNELTQLIN-----------DTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDT----EKGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTSHPFPIALSWHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQASKLLILIGEELTSRMAEKKYVGAARLRILLEAWQNNNMESFPEMSP-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . . : . : . .. : : .* . * . : : . . : : . : :. : .* . : : : :.. :. : .. . . : : . . . . :. :: . .. :: : * : ::: .:: . .. . .: :*: .* * * : : .:*:*:. : : * . .:::* : ::.*: : . . *. : :*: . .: * : :* *: ::* : : . . : .* :*:: : :: :.. .:: . :. . : : * * *::: * : .: *: ", "identical_positions": 26, "similar_positions": 141, "identity": "3.51%" }, { "cls_id": "homologset.agr.SGD:S000002367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CRB2-1", "uniprot_id": "NHP2_MOUSE", "id": "Q9CRB2-1", "name": "H/ACA ribonucleoprotein complex subunit 2", "aln": "MTKVKAAPEESEAQAEGCS------EERTYKELLVNLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRR-GVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVLCEDQNLPYVYIPSKTDLGAATGSKRPTCVIMVKP-----------HEEYQETYDKCLEEVQALPTPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX24-1", "uniprot_id": "NHP2_HUMAN", "id": "Q9NX24-1", "name": "H/ACA ribonucleoprotein complex subunit 2", "aln": "MTKIKADPDGPEAQAEACS------GERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRR-GVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNLPYVYIPSKTDLGAAAGSKRPTCVIMVKP-----------HEEYQEAYDECLEEVQSLPLPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBV6-1", "uniprot_id": "NHP2_DANRE", "id": "Q6PBV6-1", "name": "H/ACA ribonucleoprotein complex subunit 2-like protein", "aln": "MTKVKK---EKAGEEETGG------TEKSYQELIANINPIANPLASRKLSKKLYKCVKKAAKVKQIRR-GVKEVQKFINKGETGIVVFAGDTLPIDVYCHLPIMCEDRSLPYAYVPSKVDLGSSAGSKRPTCVIMIKP-----------HDEYKEAYDECVEEVTSLPKPI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32495-1", "uniprot_id": "NHP2_YEAST", "id": "P32495-1", "name": "H/ACA ribonucleoprotein complex subunit NHP2", "aln": "MGKDNK----EHKESKESK------TVDNYEARMPAVLPFAKPLASKKLNKKVLKTVKKASKAKNVKR-GVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSVPYIFIPSKQDLGAAGATKRPTSVVFIVPGSNKKKDGKNKEEEYKESFNEVVKEVQAL----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V3U2-1", "uniprot_id": "NHP2_DROME", "id": "Q9V3U2-1", "name": "H/ACA ribonucleoprotein complex subunit 2", "aln": "MGKVKVERSEDADESVVASGDVTIKEEESYDDKLIFVNAIAKPMAGKKLAKKCYKLVKKAMKHKTFLRNGLKDVQTRLRKGETGICIFAGDVTPVDIMCHLPAVCEEKGIPYTYTPSRADLGAAMGVKRGTVALLVRQ-----------NEEYKDLYDEVKEELSALNIPV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : : .*. : .:*:*:*.::* :* * :*** * * . * *:*:* . :.***.*: ::*** * :: .*:* :**::.:** : **: ***:: . ** * .::: .:**:: ::: :*: :* ", "identical_positions": 44, "similar_positions": 52, "identity": "25.73%" }, { "cls_id": "homologset.agr.SGD:S000002369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PWS4-1", "uniprot_id": "E9PWS4_MOUSE", "id": "E9PWS4-1", "name": "", "aln": "MLWVLPPPTLKNFQLLCSTDLELCPRNTSS---------TPGFHPVSAEFGSLHQALKMLWQNLHQFGQKLVRRRP-LAANE------QSESSLSRCLTTL-----------DLVSLGVGSTLGAGVYVLAGEVAREKAG--PSIIICFLIAALSSVMSGLCYAEFGARVPC-SGSAYLYSYVTVGQLLAFITGWNLILNYVIGAASVARAWSAAFDGLIGNHISQAMQTTFPIQVPSF--LAKYPDFFALGLVIVLTGILALGARESALVTRVFTGVNLLVLCFVSLSGLINGKLHNWQLTEDDYKLALL----ESNNTDSLGPMGSGGFMPFGLKGILRGTATCFFAFIGFDCIASTGEEARCPQRSIPLGIVTSLFICFLMYFGVSGALTLMIP---YYQININSPLPQAFIHVGWGPARYAVAVGTLCALSSSLIGSIFP--VPRVVYSMAEDG--LLFRKLAYVHPRTHTPVLATVLCGIIAAFMAFLVELSDLVDLSSIGTLLAYTLVTFSVLILRYQPDQV----------LSSCKREKSESAAVELEP-------------------------------------------------------------GLEPSSCMEPISPEGMPGIARTLCIPTNTTPTLR-----------SGRIVYGCASLLVFLLMLLCLILTQWSTQLFSGDPVLIAMAASLLLLTVGVITVIWRQPQSTTPLHFKVPALPVLPALSIFVNIYLMMQMTSGTWFRFGIWMVIGF----AIYFGYGIQH-------------------------------------SLEEKNDQQP--------------------------------TASSSQTLQEL---------------------------------------QEHTPSVDLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBE1-1", "uniprot_id": "D3ZBE1_RAT", "id": "D3ZBE1-1", "name": "", "aln": "---MLNMQQTSAFHVLQKATRDLSSWDYRSGAQPWEPIQHSRFSSSVSEFGSLHQALKMLWQNLHQFGQKLVRRRP-LAASE------QSESSLSRCLTTL-----------DLVSLGVGSTLGAGVYVLAGEVAREKAG--PSIIICFLIAALSSVMSGLCYAEFGARVPC-SGSAYLYSYVTVGQLLAFITGWNLILNYVIGAASVARAWSAAFDGLIGNHISQALQTTFPIQVPSF--LAKYPDFFALGLVIVLTGILALGARESAMVTRVFTGVNLLVLCFVSLSGFINGKLHNWQLTEDDYKLALS----ETNSTDSLGPLGSGGFMPFGLTGILRGTATCFFAFIGFDCIASTGEEARCPQRSIPLGIVISLFICFLMYFGVSSALTLMMP---YYQININSPLPQAFIHVGWGPARYAVAVGTLCALSSSLIGSIFP--VPRVVYSMAEDG--LLFRKLAQVHPRTHTPVLATVLCGVIAAFMAFLVELSDLVDLSSIGTLLAYSLVAFSVLVLRYQPDQN----------LSSCKKEKSDSMAVELEP-------------------------------------------------------------GLELSSCMEPMSPEGTPGIARGLCMPMDTTPTLR-----------SGRIVYGCASLLALLLVFLCLILVQWSTQLFSGNPVLIAVAVSLFLLTVGVVTVIWRQPQSTIPLHFKVPALPVLPVLSIFVNIYLMMQMTTGTWIRFGIWMVIGF----AIYFGYGIQH-------------------------------------SLEEKNDQQP--------------------------------TASSSQTP------------------------------------------QEHTPSAELP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70423-1", "uniprot_id": "CTR3_MOUSE", "id": "P70423-1", "name": "Cationic amino acid transporter 3", "aln": "----------------------------------------------------------MLWQALRRFGQKLVRRRV-LELG-------MGETRLARCLSTL-----------DLVALGVGSTLGAGVYVLAGEVAKDKAG--PSIVICFLVAALSSVLAGLCYAEFGARVPG-SGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLKMPHV--LAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKEDYCLTMS----ESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMP---YYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFP--MPRVMYSMAEDG--LLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQ----------------EMKSVEEEMELQ---------------------------------------------------------------------EETL--EAEKLTVQALFCPVNSIPTLL-----------SGRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGF----AIYFGYGIQH-------------------------------------SMKEVKNHQT--------------------------------LPKTRAQTIDL---------------------------------------DLTTSCVHSI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WY07-1", "uniprot_id": "CTR3_HUMAN", "id": "Q8WY07-1", "name": "Cationic amino acid transporter 3", "aln": "----------------------------------------------------------MPWQAFRRFGQKLVRRRT-LESG-------MAETRLARCLSTL-----------DLVALGVGSTLGAGVYVLAGEVAKDKAG--PSIVICFLVAALSSVLAGLCYAEFGARVPR-SGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHV--LAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMA----ELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMP---YYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFP--MPRVIYAMAEDG--LLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQ----------------ETK-TGEEVELQ---------------------------------------------------------------------EEAITTESEKLTLWGLFFPLNSIPTPL-----------SGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGF----AIYFGYGIQH-------------------------------------SLEEIKSNQP--------------------------------SRKSRAKTVDL---------------------------------------DPGTLYVHSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q09143-1", "uniprot_id": "CTR1_MOUSE", "id": "Q09143-1", "name": "High affinity cationic amino acid transporter 1", "aln": "----------------------------------------------------------MGCKNLLGLGQQMLRRKV-VDCS-------REESRLSRCLNTY-----------DLVALGVGSTLGAGVYVLAGAVARENAG--PAIVISFLIAALASVLAGLCYGEFGARVPK-TGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGV--LAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIVVSGFVKGSIKNWQLTEKNFS------CNNNDTN---VKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMP---YFCLDIDSPLPGAFKHQGWEEAKYAVAIGSLCALSTSLLGSMFP--MPRVIYAMAEDG--LLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQP----------NLVYQMARTTEELDRVDQNE----------------------------------------------------------LVSASESQTGFLP-VAEKFSLKSILSPKNVEPSKF-----------SGLIVNISAGLLAALIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIGF----TIYFGYGIWH-------------------------------------SEEASLAAG-----------------------------------QAKTPDSNL---------------------------------------DQCK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30825-1", "uniprot_id": "CTR1_HUMAN", "id": "P30825-1", "name": "High affinity cationic amino acid transporter 1", "aln": "----------------------------------------------------------MGCKVLLNIGQQMLRRKV-VDCS-------REETRLSRCLNTF-----------DLVALGVGSTLGAGVYVLAGAVARENAG--PAIVISFLIAALASVLAGLCYGEFGARVPK-TGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTHMTLNAPGV--LAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKE--GKPGVGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMP---YFCLDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFP--MPRVIYAMAEDG--LLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQP----------NLVYQMASTSDELDPADQNE----------------------------------------------------------LASTNDSQLGFLP-EAEMFSLKTILSPKNMEPSKI-----------SGLIVNISTSLIAVLIITFCIVTVLGREALTKGALWAVFLLAGSALLCAVVTGVIWRQPESKTKLSFKVPFLPVLPILSIFVNVYLMMQLDQGTWVRFAVWMLIGF----IIYFGYGLWH-------------------------------------SEEASLDAD-----------------------------------QARTPDGNL---------------------------------------DQCK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QFJ7-1", "uniprot_id": "A0A2R8QFJ7_DANRE", "id": "A0A2R8QFJ7-1", "name": "", "aln": "----------------------------------------------------------MVLKKLLRFGKQLLRVKV-VNCN-------SEESRLSRCLNTF-----------DLVALGVGSTLGAGVYVLAGAVARENAG--PAIVLSFLIAALASVLAGLCYAEFGARVPK-TGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFDELIGKHIEHFCRQYMSMNAPGV--LAEYPDMFSVFIILTLTGLLAFGVKESAMVNKVFTCINILVLLFMVVSGLVKGTLKNWHLDPDEILNATNSTLNATQPLPSEEMLGQGGFMPFGFTGVLSGAATCFYAFVGFDCIATTGEEVKNPQRAIPIGIVSSLLICFVAYFGVSAALTMMMP---YYMLDKNSPLPVAFKYVGWEGATYAVAVGSLCALSTSLLGAMFP--MPRVLWAMADDG--LLFKFMAGISERTKTPIKATIMSGFLAAIMAFLFDLKDLVDLMSIGTLLAYTLVAACVLVLRYQPEQF----------SQTYHIANTHEDMEMS---------------------------------------------------------------ETISTPSMGILPGVEERFSFKNLLFPDIIEPSNL-----------SGFTVNICTSLLGLLILSFSLLAVRG--GIAS---WNIITLAVLFGLCVIVTFIIWRQPESKTKLSFKVPCLPFIPVVSMFVNVYLMMQLDRGTWIRFAIWMSIGL----VIYFGYGIWH-------------------------------------STEAALAHSSM------------------DEELSVYKPACGLNRDSVTPEKEA---------------------------------------FLCNGHGSQVDDDGDI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18581-1", "uniprot_id": "CTR2_MOUSE", "id": "P18581-1", "name": "Cationic amino acid transporter 2", "aln": "---------------------------------------------------------MIPCRAVLTFARCLIRRKI-VTLDS------LEDSKLCRCLTTV-----------DLIALGVGSTLGAGVYVLAGEVAKADSG--PSIVVSFLIAALASVMAGLCYAEFGARVPK-TGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTG---LAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAR-EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMP---YYLLDEKSPLPVAFEYVRWSPAKYVVSAGSLCALSTSLLGSMFP--LPRILFAMARDG--LLFRFLARVS-KRQSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLC----------YDQPKYTPEKETLESCTN------------------------------------------------------------ATLKSESQVTMLQ--GQGFSLRTLFSPS-ALPTRQ-----------SASLVSFLVGFLAFLILGLSILTTYGVQAIARLEAWSLALLALFLVLCVAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWIRFSIWMALGF----LIYFAYGIRH-------------------------------------SLEGNPRDEED------------------DEDAFSDNINAATEEKSAMQANDH---------------------------------------HQRNLSLPFILHEKTSEC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52569-1", "uniprot_id": "CTR2_HUMAN", "id": "P52569-1", "name": "Cationic amino acid transporter 2", "aln": "---------------------------------------------------------MIPCRAALTFARCLIRRKI-VTLDS------LEDTKLCRCLSTM-----------DLIALGVGSTLGAGVYVLAGEVAKADSG--PSIVVSFLIAALASVMAGLCYAEFGARVPK-TGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLRTYFRMNYTG---LAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAR-EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMP---YYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFP--MPRVIYAMAEDG--LLFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLS----------YDQPKCSPEKDGLGSSPR------------------------------------------------------------VTSKSESQVTMLQ--RQGFSMRTLFCPS-LLPTQQ-----------SASLVSFLVGFLAFLVLGLSVLTTYGVHAITRLEAWSLALLALFLVLFVAIVLTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGF----LIYFSYGIRH-------------------------------------SLEGHLRDENN------------------EEDAYPDNVHAAAEEKSAIQANDH---------------------------------------HPRNLSSPFIFHEKTSEF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PR34-1", "uniprot_id": "CTR2_DANRE", "id": "Q5PR34-1", "name": "Cationic amino acid transporter 2", "aln": "---------------------------------------------------------MLEH--CLTFGRSLVRRKN-VDQGC------LEESKLCRCLSTV-----------DLIALGVGSTLGAGVYVLAGEVAKGSSG--PSIVVSFLIAALASVMAGLCYAEFGARVPK-TGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEIIGGHIEKFCKMYFKMSLPG---LAEYPDFFAVCLILLLSGLLSFGVKESAWVNKIFTAVNVLVLMFVIISGFVKGDSLNWNISEESLVNITVVKRNISSAANVTSDYGAGGFFPYGFGGTLAGAATCFYAFVGFDCIATTGEEVKNPQRAIPIGIVVSLLVCFLAYFGVSAALTLMMP---YYLLDEKSPLPLAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFP--LPRILFAMARDG--VLFRFLSKLS-KRQSPVAATMAAGTTAAIMAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPDAS----------FERSRISEGKEEVGESE--------------------------------------------------------------LTESESHLNMLK--DGGVTLRSLLHPP-LLPTEN-----------TSSVVNVSVIITVLVVCVVSTLNTYYGQAIIAMELWALGVLAASLFIFIICVFLICRQPQTRKKVSFMVPLLPFLPILSIFVNVYLMVQLSGDTWIRFSIWMAIGF----LIYFGYGMWH-------------------------------------SDERKRHLQN----------------------------CAVATEKKTLTGNEG---------------------------------------FVENKTH----TEKTSPC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PDY3-1", "uniprot_id": "Q2PDY3_DROME", "id": "Q2PDY3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "------------------------------------------------------------MVRQISPWKVLTRRKNLQADGS------EGETKLNRVLGLW-----------DLTALGVGSTLGAGVYVLAGQIAKDQAG--PSVMISFAIAALASLLAGVCYAEFGARVPK-AGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLLNDTLKYTFAEVAPMNVSF---LGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGALKADYSNWTVDPSTVSANST--------------IGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLP---YYIQDVNAPLPYAFEYVGWPVAMWIVTVGGLVGLLASLFGALFP--LPRVMYSMAQDG--LLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCE----------VDENPGQREVRASETTSLT-------------------------------------------------------------------SSSERFTFGSVCTQLFNVHRVQEPNAI-----------SSRIVGVLSTLFCLISLGIGVLIMQAHLLIASKEVWALTLLIVLVVLMLLVICLICLQPREARRRLFRVPFVPIVPAISIFINIYLMLQLDTWTWIRFGVWMIVGIPVFLACWYLYDCKNPAKRNPERWDFYKALKGLQESREQEYHCISKESVLTLETQLKKSPSSSLNRIQNLSDVGDELVEIKNANGKVFYVEDNKSENSTATLGSNPESPSREDEQSVIAMLDDVLNAQDTQQGQQDLDLQQQMIFERHFSLDSEMYPSVIETVIVATVHSSSDDDEVQSGITLKLSRYDECKLVAHQMLEEMFNSEAFYEQLEKVKAKEVPLVKGDKLEGEAESVNDDEASKPVFLFQRLGSQTSIISQASTIEDPLHSTKFKDRLSHIIMNANAHQVKVVAKRSEDVDGEVELEPVPDEEPKTRPLLKQSKSETDVRRLMLKAISELKIDRNETGNADEVPAEVSTTTGNPSKDPVPGAGPIAAPVAAAGGSNIPRPPKFDPVLYKTINSISLRKQRPSLNRQHIVDAKNPALLRPESQTETRPDPGEQPEPEPLPFKAKLEAILQRGPSHRTQQHPDLVRRQRPQSTYIEMEEVES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNP7-1", "uniprot_id": "Q9VNP7_DROME", "id": "Q9VNP7-1", "name": "", "aln": "---------------------------------------------------------------MTNLWKALTRRK--TEDVN------EGESQLARVLNLF-----------DLTALGVGSTLGLGVYVLAGQVAFNIAG--PAVTISFLIAAIASAFAGICYAEFAARVPK-AGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINNNMSKALNESMHIDVDF---LGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGAMNANVDNWRIPKKDVPEG----------------FGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLP---YYKQDKDAPFPHAFDSVEWYTIKWIVTIGAVFALCTSLLGAMFP--LPRILYAMGKDG--ILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQD-------------------------EEMTKLV-------------------------------------------------------------------SVKAPNVFR----QFFNGNSFREPNSM-----------TSSITKVGIVVFAIFCL-VWCSLQKVFDLDSTGGIVALSLVGAVLILICVVIG---MQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFLIWIVIGY----VIYFCYGMRN-------------------------------------STQISRSRS--------------------------------HAEVAASALQNQ---------------------GQHVNPG-----------FEPDYKVENGGRP---------------------------------------------------YEFSEKL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVM0-1", "uniprot_id": "Q9VVM0_DROME", "id": "Q9VVM0-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "-------------------------------------------------MEEFAEYYGMPSWSVTNAFRVLTRKKP-LEDSN--------ESKLAKVLSAF-----------DLTALGIGSTLGVGVYVLAGEVSKQYAG--PAVVVSFLIAAIASIFAGLCYAEFGARVPK-AGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEG---MGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEG----------------YGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLP---YFEQDEKAPLPHVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFP--LPRIVFAMSNDG--LLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVD--------------DRRESRIVANGRATGLE-------------------------------------------------------------------QDRPCALWR----RIFNLNGQTVPTKQ-----------TSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIWIAIGL----AIFLAYGIRH--------------------------------------SRLRQREQ---------------------------------RNNSIAMMRDC---------------------SNSALLG------------GQENSKYSNEVP---------------------------------------------------LILMHSTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYF2-1", "uniprot_id": "S7A14_DANRE", "id": "B0UYF2-1", "name": "Probable cationic amino acid transporter", "aln": "-----------------------------------------MSGLFAKLDPRRVQW----GANWFAFRSRVLRTKPVESMLETSGGTGAHGTKLARVLSTV-----------DLVSLGVGSCVGTGMYVVSGLVAKEMAG--PGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHSISGFMINHIGTLNGLGKGEQSYPDILALVIGILVTVIVALGVKNSVGFNNVLNVINLVVWVFIMIAGLFFVSGSNWD-------------------------EGR--FLPYGWSGVMQGAATCFYAFIGFDIIATTGEEAKSPNTSIPYAITASLVTCLTAYVSVSVILTLMVP---YTEIDSDAPLMEMFSLHGFQTAKYIVAIGSIAGLTVSLLGSLFP--MPRVIYAMAGDG--LLFRFLAHVSTYTETPAVACVVSGFLSALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPEGDIHGFVNFLSEQNSKRKEGVLAECEKEACSPVSEGDDYGGVPTN--TCGAKNLP-SLGDNE---MLIGKPDKSTYTASHPN--YGTVDMSSGIESDETDSAYLLKLKKLLGPRYYTMRIRLGLPGKMD--RPTVATGRIVTRCVVLLFILIFCFCSLIIFGSGQIADGQWWAVLLLVVLLLVLTLLVFIIIQQPENPKRLPYMAPCVPFVPASAMLVNVYLMLKLSTITWIRFGVWCFVGV----LIYFGYGMWN-------------------------------------STLEITAREEEAHAS-------------TYQRYDMGVDDNFAVDDDLYPSGDQ---------------------------------------GPFQNWGKGGQQKQPQQEQSEPQ------SDGLDR---LDNHRTSSSSSHSRAKSKASKPSPGFEALVVDDDLDDPLE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "---------------------------------------MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQD--GNAQPQKPKLTKCLNTL-----------DLTSLGIGSCCGTGMYLVAGMVAQKIAG--PGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWS-------------------------EHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVP---YDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFP--MPRVIYAMAQDG--LIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPAEVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGF----IMYFYYGITH-------------------------------------SSLEQASDDLELHVDY--SKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYN-----------------------------------YGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPG2-1", "uniprot_id": "Q9VPG2_DROME", "id": "Q9VPG2-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "----------------------------------------MPSSRRAILR-----------HILSGICTKMNRTKSVP--------TDVMETPLNRCLNTF-----------DIALLGIGHMVGAGIYVLTGTVAKEMAG--PGIILSFILAGFISMLAALCYAEFGTRVPK-AGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPG--LAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWS-------------------------EAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIP---ISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFA--LPRCMYAMASDG--LLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMER-------IHTTIRVPAVAGSPDDDDDDDE---------------------------------------------------------DVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFE-------PGSVVSVAVMLFIFLSFAICVELKVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFFVWVCIGM----VVYFLYGIRN-------------------------------------SKEGEVCSSYSILMT--------------------------TSEAGKVP------------------------------------------WGSFKATSGGKKSSKHS---------------------IFERFTGRSKPEDKKSIVEESENETSGYS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32837-1", "uniprot_id": "UGA4_YEAST", "id": "P32837-1", "name": "GABA-specific permease", "aln": "-------------------------------------MSMSSKNENKISVEQRISTDIGQAYQLQGLGSNLRSIRSKTGAGEVNYIDAAKSVNDNQLLAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPT-AGGLYYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNFEVTSGKL-----YGIFAGAVVVMCICTCVASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRMGGFNDGDFIFG-----------------KYENLSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTVFRLTSGR--------------------------------------------------------------------------------------------------------------DLFRPGPFYLGKI-----------WSPIVAWTGVAFQLFIIILVMFPSQQHGITKSTMNYACVIGPGIWILAGIYYKVYKKKYYHGPATNLSDDDYTEAVGADVIDTIMSKQEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : :*:. : ::. :. .* . : : :*.. : . .*.. :* :*. * ::* : .: : . :. :: . . . : . . : : : *. . : : :: : * : * ..: : .** . .**. . :* . *: : * : . : :: .: ::*: :. :.* ::::. *. : : : * : : :. : :. :* . :: . : . . . : . : .: . ", "identical_positions": 24, "similar_positions": 114, "identity": "1.91%" }, { "cls_id": "homologset.agr.SGD:S000002375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EUU4-1", "uniprot_id": "F7EUU4_RAT", "id": "F7EUU4-1", "name": "COP9 signalosome complex subunit 5", "aln": "MVWTNVTSGLKCHGCLESLVSVHPWWGRCKARTLRPSRIKLHLGCGDYSFSGPSAMTASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVG----------RLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYP-KGYKPPDEGPSEYQTIPLN---------------------KIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDK------------------------LAKATR---------DSCKTTIEAIHGLMSQVIKDKLFNQINVA-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35864-1", "uniprot_id": "CSN5_MOUSE", "id": "O35864-1", "name": "COP9 signalosome complex subunit 5", "aln": "-------------------------------------------------------MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVG----------RLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYP-KGYKPPDEGPSEYQTIPLN---------------------KIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDK------------------------LAKATR---------DSCKTTIEAIHGLMSQVIKDKLFNQINVA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92905-1", "uniprot_id": "CSN5_HUMAN", "id": "Q92905-1", "name": "COP9 signalosome complex subunit 5", "aln": "-------------------------------------------------------MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVG----------RLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYP-KGYKPPDEGPSEYQTIPLN---------------------KIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDK------------------------LAKATR---------DSCKTTIEAIHGLMSQVIKDKLFNQINIS-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC30-1", "uniprot_id": "CSN5_DANRE", "id": "Q6PC30-1", "name": "COP9 signalosome complex subunit 5", "aln": "---------------------------------------------------------MAGSSIAMKTWELSNSMQEVQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKLSALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVG----------RLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYP-KGYKPPDEGPSEYQTIPLN---------------------KIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQAEAQLGRGSFMLGLDTHDRKSEDK------------------------LAKATR---------DSCKTTIEAIHGLMSQVIKDKLFNQVNTSAN-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ58-1", "uniprot_id": "CSN5_DROME", "id": "Q9XZ58-1", "name": "COP9 signalosome complex subunit 5", "aln": "----------------------------------------------------------MDSDAAQKTWELENNIQTLPSCDEIFRYDAEQQRQIIDAKPWEKDPHFFKDIKISALALLKMVMHARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEVG----------RMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSAGKVCLGAFRTYP-KGYKPPNEEPSEYQTIPLN---------------------KIEDFGVHCKQYYPLEISYFKSALDRRLLDSLWNKYWVNTLGSSGLLTNTEYTTGQIMDLSEKLEQSENFLGRG-----TDVNEKRSEDK------------------------LSKATR---------DCSRSTIELIHGLMAQIVKDKLFNKVGLGK------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12468-1", "uniprot_id": "CSN5_YEAST", "id": "Q12468-1", "name": "COP9 signalosome complex subunit 5", "aln": "---------------------------------------MSLSNKTVKELRQLLKERYTVEDELTESIALSSMRFKPSQEPEFHALSQSSLLKTKLKQQSSTDIPSYTHVLISKLSCEKITHYAVRGGNIEIMGILMGFTLKDNIVVMDCFNLPVVGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRDYKGAKLNVVGWFHSHPGYDCWLSNIDIQTQDLNQRFQDPYVAIVVDPLKSLEDKILRMGAFRTIESKSDDNSATSYYELETIIFDSELNRALFETKLNLHCVIEDDESEQISLNRLIDSMKQYSYLMDSKNVRTRIKLATTSERVSNENKKNIDYQNRSTRSQFCLNTQRGDSTETSSFGSMFSGDNTSDVDMEDRNLTEFDSTDTSLCINGEPSIHVNRVERSSRSTDNFHNSKKRMNSNQERCHDEGNDMLQRNVLETDYARAKNRILASKIKQYERLRFYKDTFTL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: * . . *:. . .. : : .* :. :* *: *:. :* **.:*:**:::* . :.:::**.* *** ********* :****. *:: : . :.:**:******.****.**:.** *** :*:*:**:*:** :::. : :***** *. . . * :** :: : *::.:: : **: .: : : * .. : .. : : :* . : *. : :: . * :. : **: : :::* . .:. * *. :::: :::: ", "identical_positions": 80, "similar_positions": 113, "identity": "16.7%" }, { "cls_id": "homologset.agr.SGD:S000002376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKW1-1", "uniprot_id": "TIM22_RAT", "id": "Q9JKW1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "--MAAAKAG--ASAPEAAGSAEAPLQYSLLLQHLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ85-1", "uniprot_id": "TIM22_MOUSE", "id": "Q9CQ85-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAATAPKAG--GSAPEAAGSAEAPLQYSLLLQYLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGIFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y584-1", "uniprot_id": "TIM22_HUMAN", "id": "Q9Y584-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAAAAPNAG--GSAPETAGSAEAPLQYSLLLQYLVGDKR-QPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCGGFAAFSAAIDYYLR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IN78-1", "uniprot_id": "TIM22_DROME", "id": "Q8IN78-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "-MSVLPNAGNNESSVTAPKMFGDPDLDRMAMEYVGNMQRYRENIIIPKSNG--PVKIKTNEEKFIETAVESCGFKCTMACVMGYGLGAALGLFSASVNPNM-ADPFANEKKQTAREVFREMRSTTHSYAKNFALIGCVFSAVECTIESHRGVTDWKNGTYAGGITGGLIGLRAGVKAGIIGGLGFAAFSTAIDYYMYSR-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12328-1", "uniprot_id": "TIM22_YEAST", "id": "Q12328-1", "name": "Mitochondrial import inner membrane translocase subunit TIM22", "aln": "--MVYTGFGLEQISPAQKKPYNELTPEEQGERGAEMIMNFMTSCPGKSVVSGVTGFALGGVLGLFMASMAYDTPLHTPTPANTAATATAGNIGVGGISRTVQQISDLPFR-QQMKLQFTDMGKKSYSSAKNFGYIGMIYAGVECVIESLRAKNDIYNGVTAGFFTGAGLAYKAGPQAALMGGAGFAAFSAAIDLYMKSEDGRPPQNDFKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : . . . . :: :: . : . . * .: ..:. .: . : : : :* . * ****. :* ::: .** :** *. .* *.. :* :**. :. :** :*. :* ******:*** *: ", "identical_positions": 33, "similar_positions": 51, "identity": "15.71%" }, { "cls_id": "homologset.agr.SGD:S000002378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DD18-1", "uniprot_id": "DTD1_MOUSE", "id": "Q9DD18-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAVVQRVTRASVTVGGEQISAIGRGICVLLGISMEDSQKELEHMVRKILNLRVFEDESGKHWSKSVMDKEYEVLCVSQFTLQCVLK-GNKPDFHLAMPTEQAESFYNSFLEQLRKSYRPELIRDGKFGAYMQVHIQNDGPVTIELESPAPGAASSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNAPR-KEDRSASSGAEGDVSSEREP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEA8-1", "uniprot_id": "DTD1_HUMAN", "id": "Q8TEA8-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAVVQRVTRASVTVGGEQISAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKQYEILCVSQFTLQCVLK-GNKPDFHLAMPTEQAEGFYNSFLEQLRKTYRPELIKDGKFGAYMQVHIQNDGPVTIELESPAPGTATSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNTPR-KEDRSASSGAEGDVSSEREP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A4Q0-1", "uniprot_id": "A0A8I6A4Q0_RAT", "id": "A0A8I6A4Q0-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "------MLLAQNVTLEIYQISAIGRGICVLLGISMEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKEYEVLCVSQFTLQCVLK-GNKPDLHLAMPTEQAESFYNSFLEQLRKSYRPELIRDGKFGAYMQVHIQNDGPVTIELESPAPGAASSDPKQVTPTNNILKLTNKK--------STGKCKP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGC8-1", "uniprot_id": "DTD1_DANRE", "id": "F1QGC8-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAIIQRVTRASVTVGEEQISSIGRGLCVLLGISVEDTQKDVDYMVRKILNLRVFEDENGRAWSRSVMDGELEVLCVSQFTLQCLLK-GNKPDYHAAMPAELAQPFYNNMLEQLRETYKPELIKDGQFGAKMQVLIQNDGPVTIQLESPP---APTDPKLLSKQEKQQQRKEKTRSKGPSDSSREKAAQRSKVDPSASSGAEGDVSSEREP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGP0-1", "uniprot_id": "DTD_DROME", "id": "Q9VGP0-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "MRAVIQRVKAAKVTVLDELVSSIGPGLCVLVGIKASDTAKDVEYLVRKILALRLFEEE-GKRWQKSVKDLNLELLCVSQFTLYHRLK-GNKPDFLAAMKGEEAQELYNQFLDRLGQSYDSTKIKDGKFGAYMQVHIENDGPVTINLESPE-------------QKDTDREVDK--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07648-1", "uniprot_id": "DTD_YEAST", "id": "Q07648-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "MKIVLQKVSQASVVVDSKVISSIKHGYMLLVGISIDDSMAEIDKLSKKVLSLRIFEDESRNLWKKNIKEANGEILSVSQFTLMAKTKKGTKPDFHLAQKGHIAKELYEEFLKLLRSDLGEEKVKDGEFGAMMSCSLTNEGPVTIILDSDQ-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*.: :*:* * :*:**. .*: ::: : :*:* **:**:* . *.:.: : : *:*.****** * *.*** * . *: :*:.:*. * . ::**:*** *. : *:***** *:* ", "identical_positions": 48, "similar_positions": 44, "identity": "22.75%" }, { "cls_id": "homologset.agr.SGD:S000002383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01617-4", "uniprot_id": "CPO_DROME", "id": "Q01617-4", "name": "Protein couch potato", "aln": "------MLGSHHQLLIAATAAAAAAAAAEPQLQLQHLLPAAPTTPAVISNPINSIGPINQISSSSHPSNNNQQAVFEKAITISS-IAIKRRPTLPQTPASAPQVLSPSPK----RQCAAAVSVLP--VTVPVPVPVSVPLPVSVPVPVSVKGHPISHTHQIAHTHQISHSHPISHPHHHQLSFAHPTQFAAAVAAHHQQQQQQQAQQQQQAVQQQQQQAVQQQ---QVAYAVAASPQLQQQQQQQQHRLAQFN----QAAAAALLNQHLQQQHQAQQQQHQAQQQSLAHYGGYQLHRYAPQQQQQ----HILLSSGSSSSKHNSN---NNSNTSAGAASAAVPIATSVAAVPTTGGSLPDSPAHESHSHESNSATASAPTTPSP---------------AGSVTSAAPTATATAAAAGSAAATAAATGTPATSAVSDSNNNLNSSS----SSNSNSNAIMENQMALAPLGLSQSMDSVNTASNEEEVRTLFVSGLPMDAKPRELYLLFRAYEGYEGSLLKVTSKNGKTASPVGFVTFHTRAGAEAAKQDLQGVRFDPDMPQTIRLEFAKSNTKVSKPKPQ-PNTATTASHPALMHPLTGHLGGPFFPGGPELWHHPLAYSAAAAAELPGAAALQHATLVHPALHPQVPVRSYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07655-1", "uniprot_id": "WHI4_YEAST", "id": "Q07655-1", "name": "Protein WHI4", "aln": "MSLVHNQTNLNESKFLIERAFSSSSETVPLSKEATYPMPTAYSFSAVRSNSETNIKRENPQGFAKEPIMTSMLHNLTMSTGKGNGNDVNSLAPHDVDVGPYCLLLRNLPKDITLRECYCIFSLATGVSSIELKRDDREPFNDNEKVVVVKFGSLSLVTHYANILNSKSEIFGPSFPFRSHIDVVNEQTQLPVSFQEHVSSGTTNSSPKNYQLSSSAQNEIQNQSFNTISYGKTSSSPLGPSAAKPRPSLLSERSLRFSFNDPFGLETISQRKESVPFLRNSISQHDLSNVTTTPVPAGMPPQKDAGKSLLLLEKDEINESIWNGDELVNDVGNSSFGASLQEPPMSSTPVMEWNASSTANIPLFQLSSQENHQSNLLPPSHHSISQDVPHIQSQPNLNNSGVIHSATSLPHYHLLNQINASTKTQSIQQSVSNVPSNLDLNLQTENGHPQSSAPNGSSIFNNQKVNQGFLVSE-QDTSTISRQKECSSTASASAFSKNNETNVAGSTTISQADLSLLAKVPPPANPADQNPPCNTLYVGNLPPDATEQELRQLFSNQQGFRRLSFRNKMNSHGHGNGHGHGPICFVEFEDVSFATRALAELYGSQLPHPRPSLNNKGGIRLSFSKNPLGVRGSNSRSKSGYSFNGSYGKS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. :: * :::: :. . : : :*:* : .** **. ..* * . :..* .. : : .. :: .. .. :* ** *:* . .*: . :: : *: . * * * ** :. *. . *.*.: ::...: .. .* .. ::. :: :... *: :*:* ::*. ::*. * . : : * . . . . *: *::... ::. .*:.*:: : * *:: :* .. ..* *.: *: ..*: .** * :*...: ...* .: * .: *:*.:.:. .*: * :* : **:. . .*::.: : ..:.. *: : **::.. ** .*..:*::** . : :*: *: . : ::* * .*.:. : :.. : . . .. * .* . : . .:*::*:*: : : : : : :. .. .: : : * . .. :: ..* *. :* :: . : : : *. . : : ::: . ", "identical_positions": 82, "similar_positions": 237, "identity": "12.56%" }, { "cls_id": "homologset.agr.SGD:S000002384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B3GNI6-1", "uniprot_id": "SEP11_RAT", "id": "B3GNI6-1", "name": "Septin-11", "aln": "------MAVAVGRP----------------------SNEE--LRNLSLSGHVG---FDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDP------------ATHNEPGVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEE----TVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKK---------VEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSG-AQQTKKDKDKKN-PWLCTE--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1B7-1", "uniprot_id": "SEP11_MOUSE", "id": "Q8C1B7-1", "name": "Septin-11", "aln": "------MAVAVGRP----------------------SNEE--LRNLSLSGHVG---FDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDP------------ATHNEPGVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEE----TVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKK---------VEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSG-AQQTKKDKDKKN-PWLCTE--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVA2-1", "uniprot_id": "SEP11_HUMAN", "id": "Q9NVA2-1", "name": "Septin-11", "aln": "------MAVAVGRP----------------------SNEE--LRNLSLSGHVG---FDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDP------------ATHNEPGVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEE----TVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKK---------VEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSG-AQQTKKDKDKKN-ASFT----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1T4-1", "uniprot_id": "SEPT6_MOUSE", "id": "Q9R1T4-1", "name": "Septin-6", "aln": "-----MAAADIARQ----------------------VGED--CRTVPLAGHVG---FDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP------------ATHTQPGVQLQSNTYDLQ----------ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVSEINGTMNAHLPFAVVGSTEEVKIGNKMMRARQYPWGTVQ-VENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQEEKKK---------LEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCIE--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AA08-1", "uniprot_id": "A0A8I6AA08_RAT", "id": "A0A8I6AA08-1", "name": "Septin", "aln": "-----MAAADIARQ----------------------VGED--CRTVPLAGHVG---FDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP------------TTHTQPGVQLRSSTYDLQ----------ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVVGSTEEVKIGNKMMRARQYPWGTVQ-VENEAHCDFVKLREMLIRINMEDLREQTHARHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQEEKKK---------LEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNWQRSGFDAYWPADRGKYRVTM------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14141-1", "uniprot_id": "SEPT6_HUMAN", "id": "Q14141-1", "name": "Septin-6", "aln": "-----MAATDIARQ----------------------VGEG--CRTVPLAGHVG---FDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP------------ATHTQPGVQLQSNTYDLQ----------ESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQ-VENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFLGELQKKEEE----------------MRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKK---------LEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCTE--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKJ6-1", "uniprot_id": "A0A8M2BKJ6_DANRE", "id": "A0A8M2BKJ6-1", "name": "Septin", "aln": "MQERTMAATEIARQ----------------------AGEG--ARAVPLSGHVG---FDSMPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGEP------------TQHNQPGVQLKSNTYELQ----------ESNVRLKLTVVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----TVAEINSTMNGHLPFAVVGSTEEVKIGNKMVRARQYPWGTVQ-VENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMG-FKDTDPD-------------------------SKPFSLQETYEAKRNEFMGELQKKEEE----------------MRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKK---------LEDKKKSLDDELNGFKQKKTAAELLQSQNQQPGGSATLKKDKERKNSGFL-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CHH9-1", "uniprot_id": "SEPT8_MOUSE", "id": "Q8CHH9-1", "name": "Septin-8", "aln": "-----MAATDLERV----------------------SNAEPEPRSLSLGGHVG---FDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEE------------ASHHEECVRLRPQTYDLQ----------ESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDE----AVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMG-FQDSDGD-------------------------SQPFSLQETYEAKRKEFLSELQRKEEE----------------MRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKRK---------VEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKN---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNF1-1", "uniprot_id": "SEPT8_RAT", "id": "B0BNF1-1", "name": "Septin-8", "aln": "-----MAATDLERI----------------------SNAEPEPRSLSLGGHVG---FDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTFFNTTFETEE------------ASHHEECVRLRPQTYDLQ----------ESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDTQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDE----AVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMG-FQDSDGD-------------------------SQPFSLQETYEAKRKEFLSELQRKEEE----------------MRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKRK---------VEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKK---VGGWSSIYSVTIP-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92599-1", "uniprot_id": "SEPT8_HUMAN", "id": "Q92599-1", "name": "Septin-8", "aln": "-----MAATDLERF----------------------SNAEPEPRSLSLGGHVG---FDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEE------------ASHHEACVRLRPQTYDLQ----------ESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDE----AVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQ-VENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMG-FQDSDGD-------------------------SQPFSLQETYEAKRKEFLSELQRKEEE----------------MRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRK---------VEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKNRSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREGFL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H3-1", "uniprot_id": "SEP8A_DANRE", "id": "Q642H3-1", "name": "Septin-8-A", "aln": "-----MAATDVDIF----------------------SNEE--KRNLSLGGHVG---FDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTMFENEE------------ASHYQNGVYLRPRTYDLQ----------ESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKVKRSLFNYHDTRIHICLYFISPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDE----AVTEINSSMNAHLPFAVVGSVEEVKVGNKTVRARQYPWGVVQ-VENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMG-FKDTDPD-------------------------SQPFSLQETYEAKRKEFLGDLQKKEEE----------------MRQMFVNKVKETEAELKEKERELHEKFEQLKRMHQEEKRK---------VEEKRRELEEEMNAFNRRKVAAETLS-------LSQPLKKDKDKKN---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4FUM1-1", "uniprot_id": "SEP8B_DANRE", "id": "A4FUM1-1", "name": "Septin-8-B", "aln": "-----MAATEVNTY----------------------PTEE--MRSLSLSGHVG---FDSLPDQLVSKSVSQGFSFNILCVGETGIGKSTLMNTLFNTTFENEE------------ASHFHNGVHLRPRTYSLQ----------ESNVDLQLTIVDTVGFGDQVNKEESYKPIVDYIDAQFENFLEEELKIKRSLYNYHDSRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTVSKSELQKFKIKIMSELVSNGVQIYQFPTDDE----AVAEINSSMNAHLPFAVIGSSEEVKIGNKMVRARQYPWGVVQ-VENESHCDFVKLREMLIRVNMLDLREQTHARHYELYRRCKLEEMG-FKDTDAD-------------------------SEPFSLQETYVAKRREFIVELQMKEEQ----------------MRQMFVNKVKETEAELKEKERELHERFEMLKRTHQEEKRS---------LEEMRRDFEEEMNTFNRRKVAAETLQS----LQGSTGLKKDKEKKT---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C650-1", "uniprot_id": "SEP10_MOUSE", "id": "Q8C650-1", "name": "Septin-10", "aln": "-----MASCDEI---------------------------KEHPRSLSMCGHVG---FESLPDQLVDRSIEQGFCFNILCVGETGIGKSTLINTLFNTNFEELE------------SSHFCPCVRLRAQTYELQ----------ESNVRLKLTIVNTVGFGDQINKEDSYQPIVDYIDDQFEAYLQEEVKIKRALFNYHDSRIHVCLYFIAPTGHSLRTLDLLTMKSLDNKVNIIPLIAKADTISKSELQKFKMKLMNELVINGVQIYQFPTDDD----TTSKINGAMNGHLPFAVVGSMDEIKVGNKMVKGRQYPWGIVQ-VENENHCDFVKLREMLICTNMEDLREQTHMRHYELYRRCKLQEMG-FVDMGPE-------------------------NKPLSLQETYEAKRHEFYGERQRKEEQ----------------MKQMFVQRVKEKEAILKEAERELQAKFEHLKRIHQEERMK---------LEEKRRMLEEESVAFAKKKATCELFPNQSFLAS-GSSIRKDKDRKKADGASAFCDCLTAQESVRLCISSPRKDMD----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQK1-1", "uniprot_id": "SEP10_RAT", "id": "Q5PQK1-1", "name": "Septin-10", "aln": "-----MASCDEVR-----------------------QLKKEHTRSLTMCGHVG---FESLPDQLVDRSIEQGFCFNILCVGETGIGKSTLINTLFNTNFEELE------------SSHFCPCVRLRAQTYELQ----------ESNVRLKLTIVNTVGFGDQINKEESYQPIVDYIDNQFEAYLQEELKIKRALFNYHDSRIHVCLYFIAPTGHSLRTLDLLTMKSLDNKVNIIPLIAKADTISKSELQKFKMKLMSELVINGVQIYQFPTDDD----TTAKINGAMNGHLPFAVVGSMDEIKVGNKMVKARQYPWGIVQ-VENENHCDFVKLREMLICTNMEDLREQTHMRHYELYRRCKLQEMG-FIDIGPE-------------------------NKPLSLQETYEAKRHEFCGERQRKEEQ----------------MKQMFVQRVKEKEAILKEAERELQAKFEHLKRIHQEERMK---------LEEKRRMLEEESVAFAKKKATCELFPHQSFLAS-GSSIRRDKDRKKTDGASAFCDCITAQENVRLCISSQRKEMD----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0V9-1", "uniprot_id": "SEP10_HUMAN", "id": "Q9P0V9-1", "name": "Septin-10", "aln": "-----MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVG---FESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE------------SSHFCPNVKLKAQTYELQ----------ESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDD----TIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQ-VENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMG-FTDVGPE-------------------------NKPVSVQETYEAKRHEFHGERQRKEEE----------------MKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMK---------LEEKRRLLEEEIIAFSKKKATSEIFHSQSFLAT-GSNLRKDKDRKNSN----FL-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "------MSVEVDFVD----------------------KKEVHLRTLKQSGHVG---FDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTP------------SPHTLPSVKLKAHTYELQ----------ESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDE----TVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQ-VENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMG-FSDVDSD-------------------------NKPISFQQTFEAKRSNHLAELQSKEEE----------------VRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRK---------LEESRKALEEDYLDFQRRKQQ---------LATAHHTLTLGKSKKK---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DA97-1", "uniprot_id": "SEP14_MOUSE", "id": "Q9DA97-1", "name": "Septin-14", "aln": "-----MAEKPTNTSVPIPG--------------SEDPQKEN-IRCLSTLGHFG---FECLPTQLVNKSIQKGFSFNILCVGETGIGKTTLINTLFNTNLKETK------------SSHFYSKVGLTVKTYELL----------ERNIPLRLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSLADYHDSRIHVCLYFITPTGHSLKSLDLLTMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELNSNGIQIYQFQVDDE----ASAQVNS--SGLLPFAVVGSMEEVKVGKRMVRGRHYPWGVLQEVENENHCDFVKLRDLLLSTNMEDLKDQTHTQHYECYRSNRLQKLG-FSDTGPD-------------------------NRPVSFQEMYEAKRREFHNQCQKEEEE----------------LKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQEEILK---------LEEERRKLEEQIIDFYKMKAASESAQAQV-----CTNIKKDKDRKK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2Q660-1", "uniprot_id": "A0A1W2Q660_RAT", "id": "A0A1W2Q660-1", "name": "", "aln": "-----MAEKPINTLVQTPG--------------SEDPENEN-IRCLTTLGHFG---FECLPTQLVNKSIQKGFSFNILCVGETGIGKSTLINTLFNTNLKEAK------------SSHFYSKVGLKVKTYELL----------ERNIPLKLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSMPDYHDSRIHVCLYFITPTGHSLKSLDLITMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELSSNGVHIYQFLADDE----ATAQVNS--SGLLPFAVVGSMEEVKVGKRMVKGRHYPWGVLQ-VENENHCDFVKLRDLLLCTHMEDLKDQTHTQHYECYRSSRLQKLG-FSDKGPN-------------------------NKPVSFQEMYEAKRQEFHDQCQREEEE----------------LKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQEEILK---------LEEERRKLEEQIIDFYKMKAASESAQAQP-----CFQRSPREAGAKESCPTGSGRGERVLAASCVRTSGAVVKRQPKITPLAANPIQFHAPPSALPLRVRAPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZU15-1", "uniprot_id": "SEP14_HUMAN", "id": "Q6ZU15-1", "name": "Septin-14", "aln": "-----MAERTMAMPTQIPA--------------DGDTQKENNIRCLTTIGHFG---FECLPNQLVSRSIRQGFTFNILCVGETGIGKSTLIDTLFNTNLKDNK------------SSHFYSNVGLQIQTYELQ----------ESNVQLKLTVVETVGYGDQIDKEASYQPIVDYIDAQFEAYLQEELKIKRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTMKNLDSKVNIIPLIAKADTISKNDLQTFKNKIMSELISNGIQIYQLPTDEE----TAAQANSSVSGLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQ-VENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMG-FTDVGPN-------------------------NQPVSFQEIFEAKRQEFYDQCQREEEE----------------LKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRK---------LEEEKKQLEGEIIDFYKMKAASEALQTQL-----STDTKKDKHRKK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "-----MSTASTPPINLFRR---------------KKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEG---RYVREYPWGIIS-IDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * : : : :. . :. : .:: . . :: : : : : .* : : : :.: : * *::::.. . . ::.::: **: * ** :::* .*:*:* .**** ****.*: :*: **.:. .*::*:*:::*:.:* :* *: :: :: .: **:: .* : : * ***:: * . * *.**** :. :::: .*: *:::*: :: :::: *: ** ** :*..:. : . : ....: : : * : : : :* : ::* :*.* ::. : : :* :.. : : : : . ", "identical_positions": 63, "similar_positions": 142, "identity": "10.61%" }, { "cls_id": "homologset.agr.SGD:S000002385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62848-1", "uniprot_id": "ARFG1_RAT", "id": "Q62848-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "----MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQG------------------------------AQENRYVGFGNT--VPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-RIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAK-SPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSN--------SDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPJ9-1", "uniprot_id": "ARFG1_MOUSE", "id": "Q9EPJ9-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "----MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLETQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRASGQPQSAAASGDKAFEDWLNDDLGSYQG------------------------------AQENRYVGFGNT--VPPQKREDDFLNNAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-RIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEDSSDRPLEGHSYQNSSGDNSQNSNIDQSFWETFGSAEPPKAK-SPSSDSWTCADASTGRRSSDSWDVWGSGSASNNKNSN--------SDGWESWEGASGEGRAKATKKAAPST-ADEGWDNQNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6T3-1", "uniprot_id": "ARFG1_HUMAN", "id": "Q8N6T3-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "----MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQG------------------------------AQGNRYVGFGNT--PPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-KIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWG--SASTNRNSN--------SDGGE-----GGEGTKKAVPPAVPTD---DGWDNQNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTX5-1", "uniprot_id": "Q9VTX5_DROME", "id": "Q9VTX5-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "----MASPRTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDIELEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDKIATLAQGKSWDLKEAQGRVGSNNSFSSGGSSNSSYQSRPSATGYGGNGGYQNGGGAEPGGYQQYQTQEFKDQKEEFFSRRQVENASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTNASKLASTAKEKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAG--SNISSPQGGYNDPNFEDSSAYQRSNSVGGNLAGGLGQQSGVSDSDWGGWQDNGNSKSHMTSSSSYHNQLSSSSGGGTASAGLTRDAD-WSGFEATNYQSSETSYQNASSGGSTARRNMKLQDTSQKLSEGFESLDVKSVKPKTATASSANKGTAEDDAWNLLMN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35197-1", "uniprot_id": "GCS1_YEAST", "id": "P35197-1", "name": "ADP-ribosylation factor GTPase-activating protein GCS1", "aln": "MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAFICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHN-IDLSLPQKVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATS----QTAASATPGVAQSREGTPLENRRSATPANSSN-------------------------------GANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTPAKPPQERSAGSSNTLSLENFQADP-------------------------LGTLSRGWGLFSSAVT----KSFEDVN------------------ETVIKPHVQQWQSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAEDSSTAGNTTHTEYQKIDNNDKKNEQDED--------------------------------------KWDDF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* **: * ::: . *. *::**: ****.: .:* :*****:* **.****:*****:***::* ** :*: *** *::: :: : . :*.. .* :::*:. *.:.: :. .. : . : . * . . :: . .. . . . : .:.:. : .: . :. * : .:: .. . : . . . : . . :: . ::* .:.* . . : . : : :. .: . . . : : . : : .:: . : .:: . . . .:: . *: ", "identical_positions": 50, "similar_positions": 130, "identity": "10.53%" }, { "cls_id": "homologset.agr.SGD:S000002388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11146-1", "uniprot_id": "HSP7B_DROME", "id": "P11146-1", "name": "Heat shock 70 kDa protein cognate 2", "aln": "--MGKIP-AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN-LKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSS-QIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDD-APSGVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSHPTVEEVDG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11484-1", "uniprot_id": "SSB1_YEAST", "id": "P11484-1", "name": "Ribosome-associated molecular chaperone SSB1", "aln": "MAEGVFQGAIGIDLGTTYSCVATYESS-VEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGG-VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGERVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDPS-ADELRKAEVGLKRVVTKAMSSR-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *************..::.* ******:****.***:***. ******.****.*:*.:************:***:.:*:*:* ******: .*:* ***:: * * *:*:***:******:****. :* **:.**:********:*********:*:***************:****. . : **:**************:* * * :: **:*:*:*****:***..*::** ***:* **..:**********.********* *::::*:*:*.:* ** *.::*****:** **:**::***:.*.***:.*. *.:************:****.*:*.****: ***************.***** .:* : :****:********: *.:: :* **: :* ::: *** :***.:* : **:***. *:*.*** *:*..** * * * :*. *:::*:***:*.* ::*****.:***** ****. **::*:.:**::*. *: :: ::::.**:*: : .*:* * . *. *.. .:**:. *. : *: :. : :*:.. :*: * **. ", "identical_positions": 348, "similar_positions": 169, "identity": "54.46%" }, { "cls_id": "homologset.agr.SGD:S000002389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q0N2-1", "uniprot_id": "PTPRH_MOUSE", "id": "E9Q0N2-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MARAGGNCGVWRSLVLLGLYGCSVVRAAG----------------------------------------------------TSVTVDRHAPASSYEFSMWVEKDGVSSS-PQIPVTTAAPNPVRNLRVEGQNNISISLSWEPPDQSS------------------------LQGLTYWTQCSRH-------------------------------------------------------GGQTETRNTTDTSVTVDGLDPGSSYECSVWVEKD-GLYSKNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTTDTSITVDGLDPGSSYECSVWVE-KDGVYSTNETLSNTTAPNPVRNLRVKSQNNFSISLSWE-PPDQPSLQGLIYWAQCSRHGGQTETRNTTDTSVTVDGLDPGFLYKCSVWVEKDGVYSTNETLNTSTVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------ISASNPVRNLRVEGQNN-FSISLSWEPPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSSLQGLTYWAQCSR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HGG-----------QTETRNTADTSVTVDGLDPGSSY---------------------ECSVWVEKDGVYSTNETLNTSTVP------------------------------------AAVNITSCISTSGG----YGVLLTWSCP-------------------SGGYESFEVKVGRKWRSE------------NGSLCGKGVTVSDLEPAQSYTATVT--------------------------------------------------------TVFKDLKAQSLS----TTCHTESAAIIAGAIVGILL---LFILVGLLIVFL--------------------------------------------------------------------------KRRRKK---RQPKEVPKDLVCSCPGD-----------------------------------------------------------------------------------------------------------------------ILAKDFADHVRENEKDSNCGFAEEYQQLALEGQGQSQ---ITASALENRSKNRYRNVLPYDW-----------SRVPLQPLQEEPG-------------------------------------------------------------------------------SDYINASFMPGLW-SPKEFIATQGPLPNTVGDFWRMVWEQQ---SHTLVMLTNCMESGRV-KCEHYWPLDA---------------QPCIHGQLQVMLISEEASENWTVRHLQLFHMK-------------------EQQTLSLRQFHYLAWPDH-GVPYSPDPLLAFRKMLRQWMDQTT-DGG----------------------------------------------PPIVHCSAGVGRTGTLIALDVLLRQLE-----------------CEGLVGPFSFVKKMRESRPLMVQTEAQYVFLHQCILKSLQKPAPALVPEEAMYENVASLVYENASAIMAHESEFSASGC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD43-1", "uniprot_id": "PTPRH_HUMAN", "id": "Q9HD43-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAGGGLGVWGNLVLLGLCSWTGARAPAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGLGPGSLYTCSVWVEKDGVNSS-VGTVTTATAPNPVRNLRVEAQTNSSIALTWEVPDGPD------------------------PQNSTYGVEYTGD-------------------------------------------------------GGRAGTRSTAHTNITVDGLEPGCLYAFSMWVGKN-GINSSRETRNATTAHNPVRNLRVEAQTTSSISLSWEVPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSVEIVTSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWVG-KNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWE-VPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSG-TDITLKELEAGSLYHLTVWAERNEVRGY------------------------------------------------------------------------------NSTLTAATAPNEVTDLQNETQTK-NSVMLWWKAPG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPHSQLYVYWVQWAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTLY---------------------NFTVWAERNDVASSTQSLCASTYP------------------------------------DTVTITSCVSTSAG----YGVNLIWSCP-------------------QGGYEAFELEVGGQRGSQ------------DRSSCGEAVSVLGLGPARSYPATIT--------------------------------------------------------TIWDGMKVVSHS----VVCHTESAGVIAGAFVGILL---FLILVGLLIFFL--------------------------------------------------------------------------KRRNKK---KQQKPELRDLVFSSPGD-----------------------------------------------------------------------------------------------------------------------IPAEDFADHVRKNERDSNCGFADEYQQLSLVGHSQSQ---MVASASENNAKNRYRNVLPYDW-----------SRVPLKPIHEEPG-------------------------------------------------------------------------------SDYINASFMPGLW-SPQEFIATQGPLPQTVGDFWRLVWEQQ---SHTLVMLTNCMEAGRV-KCEHYWPLDS---------------QPCTHGHLRVTLVGEEVMENWTVRELLLLQVE-------------------EQKTLSVRQFHYQAWPDH-GVPSSPDTLLAFWRMLRQWLDQTM-EGG----------------------------------------------PPIVHCSAGVGRTGTLIALDVLLRQLQ-----------------SEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQSAQAPAEKEVPYEDVENLIYENVAAIQAHKLEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64455-1", "uniprot_id": "PTPRJ_MOUSE", "id": "Q64455-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MKPAARETRTPPRSPGLRWALLPLLLLLRQGQVLCAGAAPNPIFDIEAV-VSPTSVLLTWKHNDSGASECRIEN--KMESNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTNETLN----KTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIE------ELTTHS--SVNISGLKPGTNNSFA--FPESNETQADFAVAEEVP-DANGTKRIPVTNLSQLHKNSLVS-----------VDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIVYKIHVAG-GTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIK----QDGGEKHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQ-NTDD--ASGYTYHLVLESKSGSIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKD--PSILIPELIPGVSYTVKILTQVGDGTTS-LV---------------------------------------------------------------------------PGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELGVRSDSWDNMTRLENCTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDDTECRTEVAYLNFSTSYNISIATLSCGKMALPAQN---------------------ICTTGITDPPTPDGSPNITSVSHN------------------------------------SVKVKFSGFEASHGPIKAYAVILTTGEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNIT-------------------------------------------YNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALAITAVGGFIFWR--------------------------------------------------------------------------KKRTDA---KNNEVSFSQIKPKKSKL-----------------------------------------------------------------------------------------------------------------------IRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPK---YTAEIAENRGKNRYNNVLPYDI-----------SRVKLS-VQTHST-------------------------------------------------------------------------------DDYINANYMPGYH-SKKDFIATQGPLPNTLKDFWRMVWEKN---VYAIVMLTKCVEQGRT-KCEEYWPSK----------------QAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQ-------------------NSESHPLRQFHFTSWPDH-GVPDTTDLLINFRYLVRDYMKQIP-PES----------------------------------------------PILVHCSAGVGRTGTFIAIDRLIYQIE-----------------NENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRA-QKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JXZ9-1", "uniprot_id": "A0A0G2JXZ9_RAT", "id": "A0A0G2JXZ9-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "----------------------------------------MTRGGGRGSSRGRGSPELDATRGGWAPLAPPREAPACLGPRPLRVRSARLRRVAAAAAAAMSPGKPGAGGAGTRRTGWRRRRRRRRLEAETRAPGFGHTAGRVPGTFQGAQGMKPAARETRTPPRSPGLRWALLPLLLLLRQGQVVCAGAAPSPVFDVEAV-TSPTSVVLTWKHNDSATSEYKIN----EGNTLRYTVKNQTSFNITGLSPATSYKFSITLGTVNETSGKPTYKNITTEPWPVSDLQVAYIGVTQALLAWSNANGTASYRMQIV------ELTTNS--SGGISDLKPGTHKSLA--VQGSNETQHDLWVTEGVSADANGTEGSPVANISQLHKNSLAS-----------ADPPSARDPSLTEVLLTELKPDTQYKVTIYSQAADGTEGQPGNKVFKTNPIQVSDIRAVNISDSNMTLTWKSNNNESHASFTYKIYVAG-GSDSINETVNETQAVIRGLSSSTLYNITVLPFLGQTAGIPGFLQVYTSPRPVSDFRVTNVSLREIGLAWRSNDSESFEIFIT----QEGSEKRWNASTGDLSYIVENLKPGTSYQFEIFPRGPNGTEGPSQTVVGRTDCSAVTDIRVVSVSTTEIQLEWQ-NTDS--ASGYTYHLVLESENGS-IKTNSSQKWITVGGLTPGTLYNVTIFPEVDQMEGNSSSITQYTRPSNVSYIEVNTNTTVAAIQWKNLDAASASYSYSVLILKAGDGSNVTSRVRDI--PSVTIPGLIPGVSYEVKIFTKIRNTEVGNEV---------------------------------------------------------------------------PGQKLFCMEPAQVDSLHCEVVPKEPALVLKWACPPGMNSGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELGVRSDAWDNMTHLENCTL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNDTECRTEVTYLNFSTSYNISIATLSCGKMALPTQS---------------------TCTTGITDPPPPDGSPNITSVSHN------------------------------------SVKVKFSGFEASHGPIKAYAVLLTTGEAGQPSTDVLKYTYEDFKKGASDTYVTYLIRIEEKGQSQGLSEALNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNIT-------------------------------------------YNLQNDGLINGDESYVSFSPYSEAVSLPQDPGVICGAVFGCIFGALAIVAVGGFIFWR--------------------------------------------------------------------------KKRKDA---KNNEVSFSQIKPKKSKL-----------------------------------------------------------------------------------------------------------------------IRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPK---YAAEIAENRGKNRYNNVLPYDI-----------SRVKLS-VQTHST-------------------------------------------------------------------------------DDYINANYMPGYH-SKKDFIATQGPLPNTLKDFWRMVWEKN---VYAIVMLTKCVEQGRT-KCEEYWPSK----------------QAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQ-------------------SSESHPLRQFHFTSWPDH-GVPDTTDLLINFRYLVRDYMKQIP-PES----------------------------------------------PILVHCSAGVGRTGTFIAIDRLIYQIE-----------------NENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRA-QKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12913-1", "uniprot_id": "PTPRJ_HUMAN", "id": "Q12913-1", "name": "Receptor-type tyrosine-protein phosphatase eta", "aln": "------------------------------------------------------------MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQISSTAESFHKQNGTG-------------TPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGP----------VDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAG-ETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHIT----QEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVPSAVFDIHVVYVTTTEMWLDWK-SPDG--ASEYVYHLVIESKHGS-NHTSTYDKAITLQGLIPGTLYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKS-LE---------------------------------------------------------------------------PGRKSFCTDPASMASFDCEVVPKEPALVLKWTCPPGANAGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEVSSGAWNNATHLESCSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENGTEYRTEVTYLNFSTSYNISITTVSCGKMAAPTRN---------------------TCTTGITDPPPPDGSPNITSVSHN------------------------------------SVKVKFSGFEASHGPIKAYAVILTTGEAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEIDVGNESTTLGYYNGKLEPLGSYRACVAGFTNIT-------------------------------------------FHPQNKGLIDGAESYVSFSRYSDAVSLPQDPGVICGAVFGCIFGALVIVTVGGFIFWR--------------------------------------------------------------------------KKRKDA---KNNEVSFSQIKPKKSKL-----------------------------------------------------------------------------------------------------------------------IRVENFEAYFKKQQADSNCGFAEEYEDLKLVGISQPK---YAAELAENRGKNRYNNVLPYDI-----------SRVKLS-VQTHST-------------------------------------------------------------------------------DDYINANYMPGYH-SKKDFIATQGPLPNTLKDFWRMVWEKN---VYAIIMLTKCVEQGRT-KCEEYWPSK----------------QAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQ-------------------TSESHPLRQFHFTSWPDH-GVPDTTDLLINFRYLVRDYMKQSP-PES----------------------------------------------PILVHCSAGVGRTGTFIAIDRLIYQIE-----------------NENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRS-QKDSKVDLIYQNTTAMTIYENLAPVTTFGKTNGYIA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70289-1", "uniprot_id": "PTPRV_MOUSE", "id": "P70289-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "------------------------------------------------------------MRPLILLAALLWLQDSLAQEDVCSSLDGSPDRQGGGPPLSVSVTSRGRPTSLFLSWVAAEPGGFDYALCLRAMNLSGFPEGQQLQAHTNESSFEFHGLVPGSRYQLELTVLRPCWQNVTITLTARTAPTVVRGLQLHSTGSPASLEASWSDASGDQDSYQLLLYHPESHTLACNVSVSPDTLSYNFGDLLPGSQYVLEVITWAGSLHAK--TSILQWTEPVPPDHLRVRALGTSSLQAFWNSSEGATWFHLILTDLLEGTNLTKVVRQGISTHTFLRLSPGTPYQLKICAAAGPHQIWGPNATEWTYPSYPSDLVLTPLWNELWASWKAGQGARDGYVLKLSGPVENTTTLGPEECNAVFPGPLPPGHYTLGLRVLAGPYDAWVEGSIWLAESAARPMEVPGARLWLEGLEATKQPGRRALLYSVDAPGLLGNISVSSGATHVTFCGLVPGAHYRVDIASSMGDITQSLTGYTSPLPPQSLEIISRNSPSDLTIGWAPAPGQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLTLKSLVPGSCYTVSAWAWSGNLSSDSQKIHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGRDAFQLRLYRLRPLTLESEKILSQEAQNFSWAQLPAGYEFQVQLSTLWGSEESGSANTTGWTPPSAPTLVNVTSEAPTQLHVSWVHAAGDRSSYQVTLYQESTRTATSIVGPKADSTSFWGLTPGTKYKVEAISWAGPLYTAAAN---------------------------------------------------------------------------------VSAWTYPLTPNELLASMQAGSAVVNLAWPSGPLG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGTCHAQLSDAGHLSW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQPLSLGQDLLMLRNLIPGHTVSLSVKCRAGPLQAST---------------------HPLVLSVEPGPVEDVFCQPEATYL------------------------------------SLNWTMPTGDVAVCLVEVEQLVPGGSAHFVFQVNTSEDALLLPNLTPTTSYRLSLTVLGGNRQWSRAVTLVCTTSAEVWHPPELAEAPQVELGTGMGVTVTRGMFGKD-------------------------------------------DGQIQWYGIIATINMTLAQPSQEAINHTWYDHYYRGHDSYLALLFPNPFYPEPWAVPRS----------------------------------------WTVPVGTEDCDNTQEICNGHLKPGFQYRFSIAAFSRLSS---PETILAFSAFSEPQASISLVAMPLTVMMGTVVGCIIIVCAVLCLLCRRGLKGPRSEKNGFSQELMPYN-------------------------------------------------------------LWRTHRPIPSHSFRQSYEAKSARAHQAFFQEFEELKEVGKDQPR---LEAEHPANITKNRYPHVLPYDH-----------SRVRLT-QLSGEPH------------------------------------------------------------------------------SDYINANFIPGYS-HPQEIIATQGPLKKTVEDFWRLVWEQQ---VHVIIMLTVGMENGRV-LCEHYWPVNS---------------TPVTHGHITTHLLAEESEDEWTRREFQLQHGA-------------------EQKQRRVKQLQFTTWPDH-SVPEAPSSLLAFVELVQEEVKATQ-GKG----------------------------------------------PILVHCSAGVGRTGTFVALLPAVRQLE-----------------EEQVVDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPSDASDSGPIPVMNFAQACAKRAANANAGFLKEYRLLKQAIKDETGSLLPSPDYNQNSIASCHHSQEQLALVEESPADNMLAASLFPGGPSGRDHVVLTGSAGPKELWEMVWEHGAYVLVSLGLPDTKEKPQDIWPMEMQPIVTDMVTVHRVAESN-TAGWPSTLIRVIHGDSGTERQVQCLQFPHCETGSELPANTLLTFLDAVGQCCSRGNSKKPGTLLSHSSKVTNQLSTFLAMEQLLQQAGTERTVDVFSVALKQTQACAVKTPTLEQYIYLYNCLNSALRNRLPRARK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64612-1", "uniprot_id": "PTPRV_RAT", "id": "Q64612-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "------------------------------------------------------------MRPLILLAALLWLQGFLAEDDACSSLEGSPDRQGGGPLLSVNVSSHGKSTSLFLSWVAAELGGFDYALSLRSVNSSGSPEGQQLQAHTNESGFEFHGLVPGSRYQLKLTVLRPCWQNVTITLTARTAPTVVRGLQLHSAGSPARLEASWSDAPGDQDSYQLLLYHLESQTLACNVSVSPDTLSYSFGDLLPGTQYVLEVITWAGSLHAK--TSILQWTEPVPPDHLALRALGTSSLQAFWNSSEGATSFHLMLTDLLGGTNTTAVIRQGVSTHTFLHLSPGTPHELKICASAGPHQIWGPSATEWTYPSYPSDLVLTPLRNELWASWKAGLGARDGYVLKLSGPMESTSTLGPEECNAVFPGPLPPGHYTLQLKVLAGPYDAWVEGSTWLAESAALPREVPGARLWLDGLEASKQPGRRALLYSDDAPGSLGNISVPSGATHVIFCGLVPGAHYRVDIASSTGDISQSISGYTSPLPPQSLEVISRSSPSDLTIAWGPAPGQLEGYKVTWHQDGSQRSPGDLVDLGPDTLSLTLKSLVPGSCYTVSAWAWAGNLDSDSQKIHSCTRPAPPTNLSLGFAHQPAALKASWYHPPGGRDAFHLRLYRLRPLTLESEKVLPREAQNFSWAQLTAGCEFQVQLSTLWGSERSSSANATGWTPPSAPTLVNVTSDAPTQLQVSWAHVPGGRSRYQVTLYQESTRTATSIMGPKEDGTSFLGLTPGTKYKVEVISWAGPLYTAAAN---------------------------------------------------------------------------------VSAWTYPLIPNELLVSMQAGSAVVNLAWPSGPLG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGACHAQLSDAGHLSW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQPLKLGQELFMLRDLTPGHTISMSVRCRAGPLQAST---------------------HLVVLSVEPGPVEDVLCHPEATYL------------------------------------ALNWTMPAGDVDVCLVVVERLVPGGGTHFVFQVNTSGDALLLPNLMPTTSYRLSLTVLGRNSRWSRAVSLVCSTSAEAWHPPELAEPPQVELGTGMGVTVMRGMFGKD-------------------------------------------DGQIQWYGIIATINMTLAQPSREAINYTWYDHYYRGCESFLALLFPNPFYPEPWAGPRS----------------------------------------WTVPVGTEDCDNTQEICNGRLKSGFQYRFSVVAFSRLNT---PETILAFSAFSEPRASISLAIIPLTVMLGAVVGSIVIVCAVLCLLRWRCLKGPRSEKDGFSKELMPYN-------------------------------------------------------------LWRTHRPIPIHSFRQSYEAKSAHAHQTFFQEFEELKEVGKDQPR---LEAEHPDNIIKNRYPHVLPYDH-----------SRVRLT-QLPGEPH------------------------------------------------------------------------------SDYINANFIPGYS-HTQEIIATQGPLKKTLEDFWRLVWEQQ---VHVIIMLTVGMENGRV-LCEHYWPANS---------------TPVTHGHITIHLLAEEPEDEWTRREFQLQHGT-------------------EQKQRRVKQLQFTTWPDH-SVPEAPSSLLAFVELVQEQVQATQ-GKG----------------------------------------------PILVHCSAGVGRTGTFVALLRLLRQLE-----------------EEKVADVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPPDSSDSGPISVMDFAQACAKRAANANAGFLKEYKLLKQAIKDGTGSLLPPPDYNQNSIVSRRHSQEQFALVEECPEDSMLEASLFPGGPSGCDHVVLTGSAGPKELWEMVWEHDAHVLVSLGLPDTKEKPPDIWPVEMQPIVTDMVTVHRVSESNTTTGWPSTLFRVIHGESGKERQVQCLQFPCSESGCELPANTLLTFLDAVGQCCFRGKSKKPGTLLSHSSKNTNQLGTFLAMEQLLQQAGTERTVDVFNVALKQSQACGLMTPTLEQYIYLYNCLNSALLNGLPRAGKWPAPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62132-1", "uniprot_id": "PTPRR_MOUSE", "id": "Q62132-1", "name": "Receptor-type tyrosine-protein phosphatase R", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPVFIYDHSQDIKKSLDIA-QEAYKHNYHSPSEVQISKHHQIINSAFPRPAYDPSLNLLAESDQDLEIENLPIPA---ANVIV---------------------------------------------------------------------------------VTLQMDITKLNITLLRIFRQGVAAALGLLPQQVH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------INRLIEKKNQVELFVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGNRKPGETQALQAEEVLRSLNVDGLHQSLPQFGITD---------------------VAPEKNVLQGQHEADKIWSKEGFY------------------------------------AVVIFLSIFIIIVTCLMIIYRLKERLQLSLRQDKEKNQEIHLSPIARQQAQSEAKTTHSM---------------------VQPDQAPKVLNVVVDPQGQCTPEIRNS-------------------------------------------TSTSVCPSPFRMKPIGLQER--------------RGSNVSLTLDMSSLGSVEP-------------------------------------------------------------------------------FVAVST---PREKVAMEYLQS-----------------------------------------------------------------------------------------------------------------------------ASRVLTRSQLRDVVASSHLLQSEFMEIPMNFVDPK-----EIDIPRHGTKNRYKTILPNPL-----------SRVCLRPKNITDSL------------------------------------------------------------------------------STYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQED---SPVIVMITK-LKEKNE-KCVLYWPEKR---------------G--IYGKVEVLVTGVTECDNYTIRNLVLKQGS-------------------HT--QHVKHYWYTSWPDH-KTPDSAQPLLQLMLDVEEDRLASE-GRG----------------------------------------------PVVVHCSAGIGRTGCFIATSIGCQQLK-----------------EEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPETVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15256-1", "uniprot_id": "PTPRR_HUMAN", "id": "Q15256-1", "name": "Receptor-type tyrosine-protein phosphatase R", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQKIYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPA---ANVIV---------------------------------------------------------------------------------VTLQMDVNKLNITLLRIFRQGVAAALGLLPQQVH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------INRLIGKKNSIELFVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PINRKTGISDALPSEEVLRSLNINVLHQSLSQFGITE---------------------VSPEKNVLQGQHEADKIWSKEGFY------------------------------------AVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSM---------------------VQPEQAPKVLNVVVDPQGRGAPEIKAT-------------------------------------------TATSVCPSPFKMKPIGLQER--------------RGSNVSLTLDMSSLGNIEP-------------------------------------------------------------------------------FVSIPT---PREKVAMEYLQS-----------------------------------------------------------------------------------------------------------------------------ASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPK-----EIDIPRHGTKNRYKTILPNPL-----------SRVCLRPKNVTDSL------------------------------------------------------------------------------STYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQED---SPVIVMITK-LKEKNE-KCVLYWPEKR---------------G--IYGKVEVLVISVNECDNYTIRNLVLKQGS-------------------HT--QHVKHYWYTSWPDH-KTPDSAQPLLQLMLDVEEDRLASQ-GRG----------------------------------------------PVVVHCSAGIGRTGCFIATSIGCQQLK-----------------EEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUM3-1", "uniprot_id": "PTN7_MOUSE", "id": "Q8BUM3-1", "name": "Tyrosine-protein phosphatase non-receptor type 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQACEGRSRAQLPTLSLGADMTQP----------------------------PPTKAP-------------------------------------------------------------------------AKKHVRLQER--------------RGSSVALMLDVQSLGTVEP-------------------------------------------------------------------------------ICSVNT---PR-EVTLHFLRT-----------------------------------------------------------------------------------------------------------------------------AGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPE-----DLDIPGHASKDRYKTILPNPQ-----------SRVCLG-RAQSQED------------------------------------------------------------------------------SDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQED---VSLIVMLTQ-LREGKE-KCVHYWPTEE---------------E--AYGPFQIRIQDMKEHPEYTVRQLTIQHQQ-------------------EC--RSVKHILFSAWPDH-QTPESAGPLLRLVAEVET-PETAA-NSG----------------------------------------------PIVVHCSAGIGRTGCFIATRIGCQQLK-----------------ARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPEPNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49445-1", "uniprot_id": "PTN7_RAT", "id": "P49445-1", "name": "Tyrosine-protein phosphatase non-receptor type 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQACEGRSRAQLPTLSLGADMTQP----------------------------PPAKAP-------------------------------------------------------------------------AKKHVRLQER--------------RGSSVALMLDVRSLGTVEP-------------------------------------------------------------------------------ICSVNT---PR-EVTLHFLRT-----------------------------------------------------------------------------------------------------------------------------AGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPE-----DLDIPGHASKDRYKTILPNPQ-----------SRVCLG-RAHSQED------------------------------------------------------------------------------SDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQED---VSLIVMLTQ-LREGKE-KCVHYWPTEE---------------E--AYGPFQIRIQGMKEHPEYTVRHLTIQHQQ-------------------EC--RSVKHILFSAWPDH-QTPESAGPLLRLVAEVET-PETAA-NSG----------------------------------------------PIVVHCSAGIGRTGCFIATRIGCQQLK-----------------ARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35236-1", "uniprot_id": "PTN7_HUMAN", "id": "P35236-1", "name": "Tyrosine-protein phosphatase non-receptor type 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQAHGGRSRAQPLTLSLGAAMTQP----------------------------PPEKTP-------------------------------------------------------------------------AKKHVRLQER--------------RGSNVALMLDVRSLGAVEP-------------------------------------------------------------------------------ICSVNT---PR-EVTLHFLRT-----------------------------------------------------------------------------------------------------------------------------AGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPE-----DLDIPGHASKDRYKTILPNPQ-----------SRVCLG-RAQSQED------------------------------------------------------------------------------GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEE---VSLIVMLTQ-LREGKE-KCVHYWPTEE---------------E--TYGPFQIRIQDMKECPEYTVRQLTIQYQE-------------------ER--RSVKHILFSAWPDH-QTPESAGPLLRLVAEVEESPETAA-HPG----------------------------------------------PIVVHCSAGIGRTGCFIATRIGCQQLK-----------------ARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4B0-1", "uniprot_id": "A0A8M3B4B0_DANRE", "id": "A0A8M3B4B0-1", "name": "protein-tyrosine-phosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQDVFES---SMAEAPVGEDAPKEQDGATSHAHDP----------------LPGIG---AALWE---------------------------------------------------------------------------------RVLKASVTAGAFLLLYTLSQLTGLWVLYMLNGYR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AFPAAHKVLDLLQYLL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STSDAYDQQMEIWRVESLLPL-IATLFLGVVILGTGT---------------------LFCIKTLVPGNQSCFPEDRRQSMS------------------------------------RQPSFT---------------------YSEWTDAKQEDFYELDAVPETPVFDCFMD-------------------------MKTEADP----------------------------------------------------------------------VTLTVKPVGLQER--------------RGSNVSLTLDMCTPGTTEP-------------------------------------------------------------------------------YGALLS---PREQSTQEYLQN-----------------------------------------------------------------------------------------------------------------------------ASNLLTPEQLHTRALDDGVLQAEFYETPMNFVDPK-----EYSIPGVVRKNRYKTILPNTH-----------SRVCLKAKEEGDFL------------------------------------------------------------------------------STYINANYLKGYGGKEKAYIATQGPTVNTVGDFWRMVWQER---CPIIVMITN-IEEKNE-KCTEYWPEDS---------------V--TCEGIEITVKQVIQADDYSLRIFTVKSEG-------------------EE--RSLRQYWYTSWPDQ-KTPDKAPPLLELVQEVEEARKQAPPNSG----------------------------------------------PVIVHCSAGIGRTGCFIATSILCQQLS-----------------NEGVVDILKTTSQLRLDRGGMIQTAEQYQFVHHVLSLYERQLRETSEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35234-1", "uniprot_id": "PTN5_RAT", "id": "P35234-1", "name": "Tyrosine-protein phosphatase non-receptor type 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEKVEDDFLDLDAVPETPVFDCVMD-------------------------IKPEADP----------------------------------------------------------------------TSLTVKSMGLQER--------------RGSNVSLTLDMCTPGCNEEG------------------------------------------------------------------------------FGYLVS---PREESAHEYLLS-----------------------------------------------------------------------------------------------------------------------------ASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPK-----EYDIPGLVRKNRYKTILPNPH-----------SRVRLTSPDPEDPL------------------------------------------------------------------------------SSYINANYIRGYNGEEKVYIATQGPIVSTVVDFWRMVWQER---TPIIVMITN-IEEMNE-KCTEYWPEEQ---------------V--VHDGVEITVQKVIHTEDYRLRLISLRRGT-------------------EE--RGLKHYWFTSWPDQ-KTPDRAPPLLHLVREVEEAAQQEGPHCS----------------------------------------------PIIVHCSAGIGRTGCFIATSICCQQLR-----------------REGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEKQLSLQSSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQ------------------------------------NQEDGRLREATNG-------------------------------------------TVNS------------------------------------------------------------------------------RWS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGVSIEPRNDARNRYVNIMPYER-----------NRVHLKTLSGNDYIN-----------------------------------------------------------------------------ASYVKVNVPGQSI-EPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNRE-KCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDP------------LVGPVKTVHHFYFDLWKDM-NKPEEVVPIMELCAHSHSLNSRGN--------------------------------------------------PIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q4JDL3-1", "uniprot_id": "PTN20_HUMAN", "id": "Q4JDL3-1", "name": "Tyrosine-protein phosphatase non-receptor type 20", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPRDFRAEPVNDYEGNDSEAEDLNFRETLPSS-------------------------------SQENTPRSKVFEN-------------------------------------------KVNSEKVK--------------------------------LSLRNFPHNDYEDVFE-----EPSESGSDPSMWTARGPFRRDRWSSEDEEAAGPSQALS------------------------------------------------------------PLLSDTRKIVSEGELDQLA---------QIRPLIFNFHEQTAIKDC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKILEEKTAAYDIMQEFMALELKNLPG---EFNSGNQPSNREKNRYRDILPYDS-----------TRVPLGKS--KDYIN-----------------------------------------------------------------------------ASYIRIVNCG----EEYFYIATQGPLLSTIDDFWQMVLENN---SNVIAMITREIEGGII-KCYHYWP--------------ISLKKPLELKHFR-----VFLENYQILQYFIIRMFQVVEKS--------------TGTSHSVKQLQFTKWPDH-GTPASADSFIKYIRYARKSHLTG---------------------------------------------------PMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFN-----------------IMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKLLTLD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35822-1", "uniprot_id": "PTPRK_MOUSE", "id": "P35822-1", "name": "Receptor-type tyrosine-protein phosphatase kappa", "aln": "---MD-VAAAALPAFVALWLLYPWP--------LLGSALGQFSAGGCTFD---DGPGACDYHQDLYDD-FEWVHVSAQEPHYLPPEMPQGSYMVVDSSNHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLN------PGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQ----------------VIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAG-----QNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRG-----HNESRADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLEPNGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPSLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEQLHPHRTKREAGAME---------------------CYQVPVTYQNALSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYKGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKA--------------------------------------------------------------AATEEPEVIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVIVIVKKSK----------LAKKRKDAMGNTRQEMTHMVNAMDRSYADQS--------------------------------------------------------------------------------------TLHAEDPLSLTFMDQHNFSPRLPNDPLVPT---AVLDENHSATAESSRLLD-----------------------------------------VPRYLCEGTESPYQTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEG--------------------QSASWDVAKKDQNRAKNRYGNIIAY------------------------------------DHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMVWQ-----EQSACIVMVTNLVEVGRVKCYKYWP--DD-TEVYGDFK--------------------------------------------------------VTCVEMEPLAEYVVRTFTLERRG----YNEIREVKQFHFTGWPDHGVPYH----------------------------------ATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAER---EGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCG----------------------------------------------------------------------------------------ETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDR-----------CLPFLITIDG--------------------------------------------------------------------------------ESSNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYG---CTSIVMLNEVDLSQG---CPQYWPE----------------EGMLRYGPIQVECMSCSMDCDVINRIFRICNLT---RP--------------QEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEG----------------------------------------------RTIIHCLNGGGRSGMFCAIGIVVEMV-----------------KRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15262-1", "uniprot_id": "PTPRK_HUMAN", "id": "Q15262-1", "name": "Receptor-type tyrosine-protein phosphatase kappa", "aln": "---MDTTAAAALPAFVALLLLSPWP--------LLGSAQGQFSAGGCTFD---DGPGACDYHQDLYDD-FEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLN------PGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQ----------------VIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAG-----QNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRG-----HNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAME---------------------CYQVPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATK---------------------------------------------------------------AATEEPEVIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILIVKKSK----------LAKKRKDAMGNTRQEMTHMVNAMDRSYADQS--------------------------------------------------------------------------------------TLHAEDPLSITFMDQHNFSPRY---------------ENHSATAESSRLLD-----------------------------------------VPRYLCEGTESPYQTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEG--------------------QSASWDVAKKDQNRAKNRYGNIIAY------------------------------------DHSRVILQPVEDDPSSDYINANYID------GYQRPSHYIATQGPVHETVYDFWRMIWQ-----EQSACIVMVTNLVEVGRVKCYKYWP--DD-TEVYGDFK--------------------------------------------------------VTCVEMEPLAEYVVRTFTLERRG----YNEIREVKQFHFTGWPDHGVPYH----------------------------------ATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAER---EGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCG----------------------------------------------------------------------------------------ETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDR-----------CLPFLITIDG--------------------------------------------------------------------------------ESSNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYG---CTSIVMLNEVDLSQG---CPQYWPE----------------EGMLRYGPIQVECMSCSMDCDVINRIFRICNLT---RP--------------QEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEG----------------------------------------------RTIIHCLNGGGRSGMFCAIGIVVEMV-----------------KRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DK56-1", "uniprot_id": "PTPRU_DANRE", "id": "B3DK56-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "------------MNTCAFLLILAVQ--------IHADSVEGPTAG-CTFDEDSDPSL-CEFSQGEEDD-FDWQLFRAHASPHSTSDLLRGSYMMVNSSQHAAGQRAQLLLQTLSENDTHCVQFSYFLYSRDGHS------PGALRVYVRVNGGPLGIPVWNVSGSRGRQWHQVELAVSTFWPNEYQ----------------ILLEATVD--RKGYIAVDDILLLNYPCYKAPHFSRLGDVEVNAG-----QNATFQCVAAGRPSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQKPEQDLYRCVTQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQLNTNSILGDGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGHNTTVRECLAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEGKEVMFQTEEDIPGGIAPESLTFTPLEDMIFLKWEEPVEPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKNETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTF-DYGDMPSPLSETENTITVLLRPAQGRGAPVSTYQVVVEEEAGRKVKRELGIQD---------------------CFPIPTSHGEAQARGAPHYYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLDPRKNYLVYFQAMSNFRGETRINCIRIARK---------------------------------------------------------------AACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPRKPGNMNKTPITYRQEKSNMMGSMERSFTDQS--------------------------------------------------------------------------------------TLQEDERMALSFMDTHTCSTRS--------------DPRSS-MNESSSLLGG----------------------------------------SPRRQCGRKGSPYHTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFDG------------------------WDINKKKDKTKG-RHDTLMGY------------------------------------DRHRVKLHPLLGDPNSDYINANYID------GYHRSNHFIATQGPKQETVYDFWRMVWQ-----ENCFSIVMITKLVEVGRVKCCKYWP--DE-SEMYGDIK--------------------------------------------------------ITLLKTETLAEYTVRTFALERRG----YSAKHEVCQFHFTSWPEHGVPYH----------------------------------ATGLLAFIRRVKTSTPLDAGPVVVHCSVGAGRTGCYIVLDVMLDMAEC---EGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCG----------------------------------------------------------------------------------------ETAIPVNEFALAYKEMLRVDSQSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVLPPDR-----------ALAFLVTTEG--------------------------------------------------------------------------------ESNNYINAALMDSFH-RPAAFIVTPHPLPGTTSDFWRLVFDYG---CTSVVMLNQLNQSNSAWPCVQYWPE----------------PGLQQYGPMQVEFLSMSADEDIITRLFRVKNVT---RL--------------QEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQREC--GEG----------------------------------------------RTVVHCLNGGGRSGTYCASNILMEMI-----------------QYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYLDCLEVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q92729-1", "uniprot_id": "PTPRU_HUMAN", "id": "Q92729-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "-----------MARAQALVLALTFQ--------LCAPETETPAAG-CTFEEASDPAVPCEYSQAQYDD-FQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHS------PGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQ----------------VLFEALISPDRRGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAG-----QNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLG---SSHNQTIRECVKTEQGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISAPSF-DYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQD---------------------CFPVPLTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARK---------------------------------------------------------------AACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYP-KPVNMTKATVNYRQEKTHMMSAVDRSFTDQS--------------------------------------------------------------------------------------TLQEDERLGLSFMDTHGYSTRG--------------DQRSGGVTEASSLLGG----------------------------------------SPRRPCGRKGSPYHTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEG------------------------WDATKKKDKVKGSRQEPMPAY------------------------------------DRHRVKLHPMLGDPNADYINANYID------GYHRSNHFIATQGPKPEMVYDFWRMVWQ-----EHCSSIVMITKLVEVGRVKCSRYWP--ED-SDTYGDIK--------------------------------------------------------IMLVKTETLAEYVVRTFALERRG----YSARHEVRQFHFTAWPEHGVPYH----------------------------------ATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAEC---EGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCG----------------------------------------------------------------------------------------ETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDR-----------CLPFLISTDG--------------------------------------------------------------------------------DSNNYINAALTDSYT-RSAAFIVTLHPLQSTTPDFWRLVYDYG---CTSIVMLNQLNQSNSAWPCLQYWPE----------------PGRQQYGLMEVEFMSGTADEDLVARVFRVQNIS---RL--------------QEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAES--GDG----------------------------------------------RTIVHCLNGGGRSGTFCACATVLEMI-----------------RCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28828-1", "uniprot_id": "PTPRM_MOUSE", "id": "P28828-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "-----------MRTLGTCLVTLAG---------LLLTAAGETFSGGCLFD---EPYSTCGYSQADEDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAA------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAISTFWPNFYQ----------------VIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVG---GQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYE-FETPLNQTDNTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILK---------------------CYPVPIHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATK----------------------------------------------------------------GAVTPKPVPEPEKQTDHTVKIAGVIAG-ILLFVIIFLGVVLVMKKR----------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQG--------------------------------------------------------------------------------------TNCDEAFSFMGTHNLNGRSVSS----------------PSSFTMKTNTLSTSVPNSYYPD-----------------ETHTMASDTSSLAQPHTYKKREAADVPYQTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEG--------------------QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQMLEGDNNSDYINGNYID------GYHRPNHYIATQGPMQETIYDFWRMVWH-----ENTASIIMVTNLVEVGRVKCCKYWP--DD-TEIYKDIK--------------------------------------------------------VTLIDTELLAEYVIRTFAVEKRG----IHEIREIRQFHFTGWPDHGVPYH----------------------------------ATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAER---EGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCG----------------------------------------------------------------------------------------DTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDR-----------CLPFLITIDG--------------------------------------------------------------------------------ESSNYINAALMDSYK-QPSAFIVTQHPLPNTVKDFWRLVLDYH---CTSVVMLNDVDPAQL---CPQYWPE----------------NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAS---RP--------------QDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEG----------------------------------------------RTVVHCLNGGGRSGTFCAISIVCEML-----------------RHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8V0-1", "uniprot_id": "A0A0G2K8V0_RAT", "id": "A0A0G2K8V0-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------MRTLGTCLVTLAG---------LLLTAAGETFSGGCLFE---EPYSTCGYSQADDDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAA------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAVSTFWPNFYQ----------------VIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVRYCYQVG---GQEQVREEVSWDMDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYE-FETPLNQTDNTVTVLLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILK---------------------CYPVPIHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATKAAIIVTQL---------------------------------------TTPYIRIAPAAGDGQLTGAVTPKPVPEPEKGTDHTVKIAGVIAG-ILLFVIIFLGVVLVMKKR----------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQG--------------------------------------------------------------------------------------TNCDEAFSFMDTHNLNGRSVSS----------------PSSFTMKTNTLSTSVPNSYYPDPFVPTAILVPI----NDETHTMASDTSSLAQPHTYKKREAADVPYQTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEG--------------------QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQMLEGDNSSDYINGNYID------GYHRPNHYIATQGPMQETVYDFWRMVWY-----ENTASIIMVTNLVEVGRVKCCKYWP--DD-TEIYKDIK--------------------------------------------------------VTLIDTELLAEYVIRTFAVEKRG----IHEIREIRQFHFTGWPDHGVPYH----------------------------------ATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAER---EGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCG----------------------------------------------------------------------------------------DTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDR-----------CLPFLITIDG--------------------------------------------------------------------------------ESSNYINAALMDSYK-QPSAFIVTQHPLPNTVKDFWRLVLDYH---CTSVVMLNDVDPTQL---CPQYWPE----------------NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAS---RP--------------QDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEG----------------------------------------------RTVVHCLNGGGRSGTFCAISIVCEML-----------------RHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28827-1", "uniprot_id": "PTPRM_HUMAN", "id": "P28827-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "-----------MRGLGTCLATLAG---------LLLTAAGETFSGGCLFD---EPYSTCGYSQSEGDD-FNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNSP------PGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQ----------------VIFEVITS-GHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAG-----QFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG---GQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYE-LETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKTTEILK---------------------CYPVPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATK----------------------------------------------------------------GAATPKPVPEPEKQTDHTVKIAGVIAG-ILLFVIIFLGVVLVMKKR----------KLAKKRKETMSSTRQEMTVMVNSMDKSYAEQG--------------------------------------------------------------------------------------TNCDEAFSFMDTHNLNGRSVSS----------------PSSFTMKTNTLSTSVPNSYYPD-----------------ETHTMASDTSSLVQSHTYKKREPADVPYQTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEG--------------------QSAPWDSAKKDENRMKNRYGNIIAY------------------------------------DHSRVRLQTIEGDTNSDYINGNYID------GYHRPNHYIATQGPMQETIYDFWRMVWH-----ENTASIIMVTNLVEVGRVKCCKYWP--DD-TEIYKDIK--------------------------------------------------------VTLIETELLAEYVIRTFAVEKRG----VHEIREIRQFHFTGWPDHGVPYH----------------------------------ATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAER---EGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCG----------------------------------------------------------------------------------------DTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDR-----------CLPFLITIDG--------------------------------------------------------------------------------ESSNYINAALMDSYK-QPSAFIVTQHPLPNTVKDFWRLVLDYH---CTSVVMLNDVDPAQL---CPQYWPE----------------NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAA---RP--------------QDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEG----------------------------------------------RTVVHCLNGGGRSGTFCAISIVCEML-----------------RHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99M80-1", "uniprot_id": "PTPRT_MOUSE", "id": "Q99M80-1", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "-----------MGSLGGLALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFD---EHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSS------PGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQ----------------VIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVG-----QNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN---QQQYEAEEVIQTSS----HYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYD-ADTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIE---------------------CFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGAPMGSAQ---------------------------------------VTPGTPLCLLT-----TASTQNSNTVEPEKQVDNTVKMAGVIAG-LLMFIIILLGVMLTIKRR----------KLAKKQKETQSGAQREMG-PVASTDKPTAKLG--------------------------------------------------------------------------------------TNRNDEGFSSSSQDVNGFTDGS----------------RGELSQPTLTIQT-----------------------------------------HPYRTCDPVEMSYPRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEG--------------------QTASWDTAKEDENRNKNRYGNIISY------------------------------------DHSRVRLLVLDGDPHSDYINANYID------GYHRPRHYIATQGPMQETVKDFWRMIWQ-----ENSASIVMVTNLVEVGRVKCVRYWP--DD-TEVYGDIK--------------------------------------------------------VTLIETEPLAEYVIRTFTVQKKG----YHEIRELRLFHFTSWPDHGVPCY----------------------------------ATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAEN---EGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCG----------------------------------------------------------------------------------------NTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDR-----------CLPFLISVDG--------------------------------------------------------------------------------ESSNYINAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYN---CSSVVMLNEMDTAQL---CMQYWPE----------------KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMA---RP--------------QDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREG----------------------------------------------RTVVHCLNGGGRSGTFCAICSVCEMI-----------------QQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14522-3", "uniprot_id": "PTPRT_HUMAN", "id": "O14522-3", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "-----------MASLAALALSLL----LRLQLPPLPGARAQSAAGGCSFD---EHYSNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSS------PGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQ----------------VIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVG-----QNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN---QQQYEAEEVIQTSS----HYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYD-TDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIE---------------------CFSVPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG---------------------------------------------------------------ASTQNSNTVEPEKQVDNTVKMAGVIAG-LLMFIIILLGVMLTIKRRRNAYSYSYYLKLAKKQKETQSGAQREMG-PVASADKPTTKLS--------------------------------------------------------------------------------------ASRNDEGFSSSSQDVNGFTDGS----------------RGELSQPTLTIQT-----------------------------------------HPYRTCDPVEMSYPRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEG--------------------QTASWDTAKEDENRNKNRYGNIISY------------------------------------DHSRVRLLVLDGDPHSDYINANYID------GYHRPRHYIATQGPMQETVKDFWRMIWQ-----ENSASIVMVTNLVEVGRVKCVRYWP--DD-TEVYGDIK--------------------------------------------------------VTLIETEPLAEYVIRTFTVQKKG----YHEIRELRLFHFTSWPDHGVPCY----------------------------------ATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAEN---EGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCG----------------------------------------------------------------------------------------NTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDR-----------CLPFLISVDG--------------------------------------------------------------------------------ESSNYINAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYN---CSSVVMLNEMDTAQF---CMQYWPE----------------KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMA---RP--------------QDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREG----------------------------------------------RTVVHCLNGGGRSGTFCAICSVCEMI-----------------QQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64487-4", "uniprot_id": "PTPRD_MOUSE", "id": "Q64487-4", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "----------MVPVARPLSLLLTFFLC-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVS-YYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQH--------VNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS-DTIASYELVYRDGD-QGEEQRITIEP---------GTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPP-VDTFG-PLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFP---------QNLHSEGTTST-SVQLSWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVP-----ADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPDVPANENIKGYYIIIVPLKKSRG-KFIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVEL-KPYIAAHFD--VLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAES-------KMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRK------RAESESRKSSLPNSKEVPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLKFSQEYESIDPG--------------------QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIEGIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWE-----QRSATVVMMTKLEERSRVKCDQYWP--SRGTETHGLVQ--------------------------------------------------------VTLLDTVELATYCVRTFALYKNG----SSEKREVRQFQFTAWPDHGVPEH----------------------------------PTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCG----------------------------------------------------------------------------------------NTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYES-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFLDGYR-QQKAYIATQGPLAETTEDFWRMLWEHN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LD14-1", "uniprot_id": "A0ABK0LD14_RAT", "id": "A0ABK0LD14-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "---MPLTSCRMVPVARLLLLLLAFFLY-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS---GGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRG-RNVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVS-YYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQH--------VNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS-DTIASYELVYRDGD-QGEEQRITIEP---------GTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDYRPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDATEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGRPRLVINHTQMNTALIQWHPP-VDTFG-PLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYIFRLSARNKVGFGEEMVKEISVPEEVPTGFP---------QNLHSEGTTST-SVQISWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVP-----ADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPDVPANENIKGYYIIIVPLKKSRG-KFIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVEL-KPYIAAHFD--VLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAES-------KMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRK------RAESESRKSSLPNSKEVPSHHPTDPVELRRLNFQTPGSD--DSGYPGNLHFSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPG--------------------QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIEGIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWE-----QRSATVVMMTKLEERSRVKCDQYWP--SRGTETHGLVQ--------------------------------------------------------VTLLDTVELATYCVRTFALYKNG----SSEKREVRQFQFTAWPDHGVPEH----------------------------------PTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCG----------------------------------------------------------------------------------------NTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYES-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFLDGYR-QQKAYIATQGPLAETTEDFWRMLWEHN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23468-1", "uniprot_id": "PTPRD_HUMAN", "id": "P23468-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "----------MVHVARLLLLLLTFFLR-TDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVS-YYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVN--NIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQH--------VNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS-DTIANYELVYKDGE-HGEEQRITIEP---------GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPP-VDTFG-PLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFP---------QNLHSEGTTST-SVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVP-----ADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-GMITVQLPEVPANENIKGYYIIIVPLKKSRG-KFIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVEL-KPYIAAHFD--VLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAES-------KMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRK------RAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLKFSQEYESIDPG--------------------QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVLLSAIEGIPGSDYVNANYID------GYRKQNAYIATQGSLPETFGDFWRMIWE-----QRSATVVMMTKLEERSRVKCDQYWP--SRGTETHGLVQ--------------------------------------------------------VTLLDTVELATYCVRTFALYKNG----SSEKREVRQFQFTAWPDHGVPEH----------------------------------PTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCG----------------------------------------------------------------------------------------NTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHT--SRFISANLPCNKFKNRLVNIMPYES-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFWRMLWEHN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V2N1-1", "uniprot_id": "PTPRS_MOUSE", "id": "B0V2N1-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "--MAPTWSPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVS-YYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHP--------VGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ-ESVIKYELLFREGD-RGREVGRTFDP---------TTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPP-ADAAEDPVLGYRLQFGREDAAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFP---------QILGAAGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD-PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG--LTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDND-GFIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPVLLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARFS--ILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKNE--------PTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKP--DSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--------------------QQFTWEHSNLEANKPKNRYANVIAY------------------------------------DHSRVILQPLEGIMGSDYINANYVD------GYRRQNAYIATQGPLPETFGDFWRMVWE-----QRSATVVMMTRLEEKSRIKCDQYWP--NRGTETYGFIQ--------------------------------------------------------VTLLDTMELATFCVRTFSLHKNG----SSEKREVRHFQFTAWPDHGVPEY----------------------------------PTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKT---EKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCG----------------------------------------------------------------------------------------NTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHT--SRFITASLPCNKFKNRLVNILPYES-----------SRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFWRALWENN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GAPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64605-1", "uniprot_id": "PTPRS_RAT", "id": "Q64605-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "--MAPTWRPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVS-YYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHP--------VGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ-ESVIKYELLFREGD-RGREVGRTFDP---------TTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPP-ADAAEDPVLGYRLQFGREDAAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEASAALSIPEDAPRGFP---------QILGAAGNVSAGSVILRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD-PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG--LTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDND-GSIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPILLGSPEDMDLEELIQD--LSRLQRRSLRHSRQLEVPRPYIAARFS--ILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKNE--------PTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKP--DSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--------------------QQFTWEHSNLEANKPKNRYANVIAY------------------------------------DHSRVILQPLEGIMGSDYINANYVD------GYRRQNAYIATQGPLPETFGDFWRMVWE-----QRSATVVMMTRLEEKSRVKCDQYWP--NRGTETYGFIQ--------------------------------------------------------VTLLDTMELATFCVRTFSLHKNG----SSEKREVRHFQFTAWPDHGVPEY----------------------------------PTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIRT---EKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCG----------------------------------------------------------------------------------------NTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHT--SRFITASLPCNKFKNRLVNILPYES-----------SRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFWRALWENN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GAPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13332-1", "uniprot_id": "PTPRS_HUMAN", "id": "Q13332-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "--MAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVS-YYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVN--SIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHP--------VGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ-ESIIKYELLFREGD-HGREVGRTFDP---------TTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPP-AGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHP---------QILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRD-QVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG--LTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDAD-GFIMVYLPDGQSPVPVQSYFIVMVPLRKSRGGQFLTPLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARFS--VLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKSE--------PTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKP--DSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--------------------QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVILQPIEGIMGSDYINANYVD------GYRCQNAYIATQGPLPETFGDFWRMVWE-----QRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYGFIQ--------------------------------------------------------VTLLDTIELATFCVRTFSLHKNG----SSEKREVRQFQFTAWPDHGVPEY----------------------------------PTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKP---EKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCG----------------------------------------------------------------------------------------NTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPYES-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFWRMLWENN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAP8-1", "uniprot_id": "A0AB32TAP8_DANRE", "id": "A0AB32TAP8-1", "name": "protein-tyrosine-phosphatase", "aln": "--MMPTG--HLPILLSLSALLLSPLLTGSLALSSPRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVNSQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGEINVQAKLSIIREDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLR---------SGALQIENTEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSILPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQITVKSLPKPPGTPVVTETTATSITITWDSGNPEPVS-HYIIQYRAKSPESKFETVDSITTTRYSIGGLSPNTDYEIRVSAFN--TIGQGPPSEPVEARTGEQAPASPPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLP--------MSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQGVPGQPTNFQVGEVSDTGVELTWEPAFEKEGIISYELHYKEGK-DGPLGKKKFAP---------TSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQAKPSAPPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAGAEVSTEHVEAP-TSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDEDVPGAPPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWEMDDTAEYEMVIGGLQPDTTYSITVAAYTTKGDGARSKPKLVLTKGAVPGPPFLSVNQNSESTAIIRWQPPDYVAPGLEVQGYRLQFGRKDVNPLATLEFGPQELEYSISNIHRGATYIFKVSAKSKSGFGEEATQELRVPEEVPRGYP---------QITEGS-NITCCSVQFSWLPPVLAERNGAITEYTLSYQEAGTISGPKELRLPAD-----ENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAYE-ADVPRNFTVKLVTKTTVLLSWKF---YDSRFPYKCTIEYHRQKSDIDARMTKTLITNLRPNTTYEFRISCQDSSDGGPKHKLVARTAPHIQIRKPELDLKRESE-STLTIVFPPLETKDLIKAIYVVVVPLKKGKG--PMRHIKSPDELDLEELLGERRLGLHHSGTTRQLKQVDGKRPYIAASFKPSSMPPSFTLGNQMMYGSFENRALDRGQEYVLFILAELNTTGV-------KAFVSSPYTDPIMAPDLDPQPLESGGDGLIWVVGPVLAVVFIICIVIAILLYKNSKPDSSKRKESEPRTKCLLNNADITPHHPTDPVEMRRINFQTPDSGLSSPVSEAGFDYESMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPG--------------------QQFTWEHSNLEVNKPKNRYANVIAY------------------------------------DHSRVILAPIEGITGSDYINSNYID------GYRKQNAYIATQGPLPETFGDFWRMVWE-----QRAATVVMMTRLEEKSRIKCDQYWP--SRGTETYGMIQ--------------------------------------------------------VTLLDTIELATFCVRTFSLHKNG----SSEKREVRQFQFTAWPDHGVPEY----------------------------------PTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKH---EKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACG----------------------------------------------------------------------------------------NTEVAARSLFSYIQKLAQVEAGEHVSGMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPYET-----------TRVCLQPIRGL-------------------------------------------------------------------------------EGSDYINSSFIDGYR-QQKAYIATQGPLAETTEDFWRMLWENN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTVRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PISVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2A8L5-1", "uniprot_id": "PTPRF_MOUSE", "id": "A2A8L5-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVS-FYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRP--------LSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQ-ERIVKYELVYWAAEDEGQQHKVTFDP---------TSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPP--KELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFP---------QNLRVTGLTTS-TTELTWDPPVLAERNGHITNYTVVYRDINSQ---LELQNVTN-----DTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVE-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNG--QSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPQKPLPASAFIED-GRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWNTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQVD--VLPDTFTLGDKKSYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKRKRT-----HSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--------------------QQFTWENSNSEVNKPKNRYANVIAY------------------------------------DHSRVLLTSIDGVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWE-----QRTATVVMMTRLEEKSRVKCDQYWP--VRGTETYGLIQ--------------------------------------------------------VTLVDTVELATYTMRTFALHKSG----SSEKRELRQFQFMAWPDHGVPEY----------------------------------PTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCG----------------------------------------------------------------------------------------HTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHT--SRFVSANLPCNKFKNRLVNIMPYEL-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHN---STIIVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PITVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64604-1", "uniprot_id": "PTPRF_RAT", "id": "Q64604-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVS-FYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRP--------LSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQ-ERIIKYELVYWAAEDEGQQHKVTFDP---------TSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPP--KELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFP---------QNLRVTGLTTS-TTELAWDPPVLAERNGRITNYTVVYRDINSQ---HELQNVTG-----DVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPME-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNG--QSVEVDGHSMRKLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLPQKPLPASAFIED-GRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQVD--ELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKRKRT-----HSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--------------------QQFTWENSNSEVNKPKNRYANVIAY------------------------------------DHSRVLLTSIDGVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWE-----QRIATVVMMTRLEEKSRVKCDQYWP--ARGTETYGLIQ--------------------------------------------------------VTLVDTVELATYTMRTFALHKSG----SSEKRELRQFQFMAWPDHGVPEY----------------------------------PTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCG----------------------------------------------------------------------------------------HTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLAGSKARA--SRFISANLPCNKFKNRLVNIMPYEL-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHN---STIIVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PITVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10586-1", "uniprot_id": "PTPRF_HUMAN", "id": "P10586-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "MAPEPAPGR--TMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVT-YYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVN--SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRP--------PNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQ-ERIIMYELVYWAAEDEDQQHKVTFDP---------TSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFP---------QNLHVTGLTTS-TTELAWDPPVLAERNGRIISYTVVFRDINSQ---QELQNITT-----DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVE-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNG--QSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIED-GRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTPRWSTPEELELDELLEA--IEQGGEEQRRRRRQAERLKPYVAAQLD--VLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPAQQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKRKRT-----HSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--------------------QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVILTSIDGVPGSDYINANYID------GYRKQNAYIATQGPLPETMGDFWRMVWE-----QRTATVVMMTRLEEKSRVKCDQYWP--ARGTETCGLIQ--------------------------------------------------------VTLLDTVELATYTVRTFALHKSG----SSEKRELRQFQFMAWPDHGVPEY----------------------------------PTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCG----------------------------------------------------------------------------------------HTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHT--SRFISANLPCNKFKNRLVNIMPYEL-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFWRMLWEHN---STIIVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PITVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IFW2-1", "uniprot_id": "PTPRF_DANRE", "id": "A4IFW2-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "MVPNTCTSVPLLPVGLPLLLLLSCIQFSSQADSLPNFVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSLGEINTSAKLTVLEENQIPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDING-NGRIKQLRSG---------ALQIENSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPEPVS-YYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVN--NIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAP--------LSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQ-DPIIKYELQYWEADSDNK-IHVTFDP---------AGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFP---------LNLQVVGLTTS-TTRLTWEPPALSERNGRIIHYIVVYRDINSK---QNSTNRTS-----DTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTS-PAFATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYNQ--QSVEVQGNLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFKTKPVLYTADQTNNGKLTINLPKVPTSAPVRCYYIVVVPVSQTS----SRQWINPDEMELDELLES--SE-GAHLRRRRRHT-DTVRPYIAAKLS--TLPETFTLGDELDYSGFINRPLPNNQHFQCFVMAELKDQYPVTANEKQRTFSASPYSDPIIVQGENQMQRSVDQPEMLWVMGPVLAVVLIIIIVIAILLFKRKR------ASPLPKDDHSGGVKDCLLASSSDPVEMRRLNYQTPG----------------MREHPPISVSELADHIERLKANDALRFSQEYESIDPG--------------------QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVVLTPVDGVPGSDYINSNYID------GYRKQNAYIATQGPLPETLSDFWRMIWE-----QRASTIVMMTRLEEKSRVKCDQYWP--IRGTETYGMIQ--------------------------------------------------------VTMLDAVELATYSVRTFALYKNG----SSEKREVRQFQFMAWPDHGVPEY----------------------------------PTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCG----------------------------------------------------------------------------------------NTEVPARNLYAHIQKLTQPSAGETVTAMELEFKRLANSKAHT--SRFISANLPCNKFKNRLVNIMPFES-----------TRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASCIDGYR-QQKAYIATQGPLAETTEDFWRMLWEHN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PITVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TXQ6-1", "uniprot_id": "A0AB32TXQ6_DANRE", "id": "A0AB32TXQ6-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "MVPQTRQGS--ARHGATSLLLLLCLAVPIHADSMPSFVKTPEDQTGISGGVASFVCQAVGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGG---TPIRGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVR----VRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGMIDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVS-YYVIQYRSKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVN--NIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFP--------LSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQ-DQITKYELTYWEADSDNK-HHVIFDP---------AGSYAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQ---------EAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGNTALIQWQPP--KEMVGELMGYRLRYKREEEDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYP---------QNLKVVGLTTT-TTKLAWDPPPLPERNGKIVRYVVVYRDINSH---QNQTNGTA-----DTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMKTSVLLTWEVPETYKSQVPFKILYNQ--QSVEVQGDLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFTTKPAHQKLDPEEGGKLAITLPEVHNSALVRWFYIVVVPVTPST----LRHWENPEDIDLDELMGN--NR-DAAVRRRRRQTQDFLRPYIAAKLE--SLPERFVLGDEKTYSNYYNKPLPGQQQYRTFILAALKD--------RDSTFTVSPFSEPMMVKLHSGMSRHVEDPEMLWVMGPVLAVVLIIIIVIAILLFKRKR------TSPSAKDEHSAGVKDHLLAHSSDPVEMRRLNYQTQGSS-----AFNCPSTSRMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--------------------QQFTWENSNLEVNKPKNRYANVIAY------------------------------------DHSRVVLTPVDGVPGSDYINGNYID------GYRKQNAYIATQGPLPETLSDFWRMVWE-----QRTSTIVMMTRLEEKSRVKCDQYWP--SRGTETYGMIQ--------------------------------------------------------VSMLDTVELATYSVRTFALYKNG----SSEKREVRQFQFMAWPDHGVPEY----------------------------------PTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH---EKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCG----------------------------------------------------------------------------------------NTEVPARSLYTHIQKLTQAPPGDTVTAMELEFKKLANSKAHT--SRFISASLPCNKFKNRLVNIMPFES-----------SRVCLQPIRGV-------------------------------------------------------------------------------EGSDYINASFIDGYR-QQKAYIATQGPLSETTEDFWRMLWEHN---STIVVMLTKLREMGRE-KCHQYWPA----------------ERSARYQYFVVDPMAEYNMPQYILREFKVTDAR-------------------DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQF-GQDG----------------------------------------------PITVHCSAGVGRTGVFITLSIVLERM-----------------RYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18052-1", "uniprot_id": "PTPRA_MOUSE", "id": "P18052-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILVLFGSGLIHVSANNATTVSPSLGTTRLIKTSTTELAKEENKTSNSTSSVISLSVAPTFSPNLTLEPTYVTTVNSSHSDNGTR--------------------------RAASTESGGTTISPN---GSWLIENQFTDAITEPWEGNSSTAATTPETFPP---------ADETPIIAVMVALSSLLVIVFII-------------------------------------------------------------------------------------IVLYMLRFKKYKQAGSHSNSF------------------------RLSNGRTEDVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQSVPLLARSPSTN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACP-------------------IQATCEAASKEENKEKNRYVNILPFLSLAVSKDAVKALNKTTPLLERRFIGKSNSRGCLSDDHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWE-----QNTATIVMVTNLKERKECKCAQYWP--DQGCWTYGNVR--------------------------------------------------------VSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHS---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYG----------------------------------------------------------------------------------------DTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQN--DKMRTGNLPANMKKNRVLQIIPYEF-----------NRVIIPVKRGE-------------------------------------------------------------------------------ENTDYVNASFIDGYR-QKDSYIASQGPLLHTIEDFWRMIWEWK---SCSIVMLTELEERGQE-KCAQYWPS----------------DGLVSYGDITVELKKEEECESYTVRDLLVTNTR-------------------ENKSRQIRQFHFHGWPEV-GIPSDGKGMINIIAAVQKQQQQS-GNH-----------------------------------------------PITVHCSAGAGRTGTFCALSTVLERV-----------------KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03348-1", "uniprot_id": "PTPRA_RAT", "id": "Q03348-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPTFSPNLTLEPTYVTTVNSSHSDNGTK--------------------------RAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNSSSAATTPETFPP---------ADETPIIAVMVALSSLLVILFII-------------------------------------------------------------------------------------IVLYMLRFKKYKQAGSHSNSF------------------------RLSNGRTEDVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQSVPLLARSPSTN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACP-------------------IQATCEAASKEENKEKNRYVNLLPY------------------------------------DHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWE-----QNTATIVMVTNLKERKECKCAQYWP--DQGCWPYGNVR--------------------------------------------------------VSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHS---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYG----------------------------------------------------------------------------------------DTELEVTSLDTHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQN--DKMRTGYLPANMKKNRVLQIIPYEF-----------NRVIIPVKRGE-------------------------------------------------------------------------------ENTDYVNASFIDPYR-QKDSYIASQGPLLHTTEDFWRMIWEWK---SCSIVMLTELEERGQE-KCAQYWPS----------------DGLVSYGDITVELKKEEECESYTVRDLLVTNTR-------------------ENKSRQIRQFHFHGWPEV-GIPSDGKGMINIIAAVQKQQQQS-GNH-----------------------------------------------PITVHCSAGAGRTGTFCALSTVLECV-----------------KAEGILDVFQTVKTLRLQRPHMVQILEQYEFCYKVVQEYIDAFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18433-5", "uniprot_id": "PTPRA_HUMAN", "id": "P18433-5", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTT--------------------------RTASTNSIGITISPN---GTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFII-------------------------------------------------------------------------------------IVLYMLRFKKYKQAGSHSNSF------------------------RLSNGRTEDVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQSVPLLARSPSTN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACP-------------------IQATCEAASKEENKEKNRYVNILPY------------------------------------DHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRMIWE-----QNTATIVMVTNLKERKECKCAQYWP--DQGCWTYGNIR--------------------------------------------------------VSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHT---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYG----------------------------------------------------------------------------------------DTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQN--DKMRTGNLPANMKKNRVLQIIPYEF-----------NRVIIPVKRGE-------------------------------------------------------------------------------ENTDYVNASFIDGYR-QKDSYIASQGPLLHTIEDFWRMIWEWK---SCSIVMLTELEERGQE-KCAQYWPS----------------DGLVSYGDITVELKKEEECESYTVRDLLVTNTR-------------------ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQS-GNH-----------------------------------------------PITVHCSAGAGRTGTFCALSTVLERV-----------------KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2GV87-1", "uniprot_id": "PTPRE_RAT", "id": "B2GV87-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPFCPLLLASFSLSLATAGQGNDTTP----------------------------------------------------------------------------------------------------------------------------TESNWTSTTAGPPDP----------GTSQPLLTWLLLP--LLLLLFL-------------------------------------------------------------------------------------LAAYFFRFRKQRKAVVNSNDK------------------------KMPNGILEEQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQRVMLLSRSPSGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKYFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGH-------------------IQGTFELANKEENREKNRYPNILPN------------------------------------DHCRVILSQLDGIPCSDYINASYID------GYKEKNKFIAAQGPKQETVNDFWRMVWE-----QRSATIVMLTNLKERKEEKCYQYWP--DQGCWTYGNIR--------------------------------------------------------VCVEDCVVLVDYTIRKFCIHPQLPDSCKAP-RLVSQLHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHS---EQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYG----------------------------------------------------------------------------------------DTELDVSSLERHLQTLHGTATHFDKIGLEEEFRKLTNVRIMK--ENMRTGNLPANMKKARVIQIIPYDF-----------NRVILSMKRGQ-------------------------------------------------------------------------------EFTDYINASFIDGYR-QKDYFMATQGPLAHTVEDFWRMVWEWK---SHTIVMLTEVQEREQD-KCYQYWPT----------------EGSVTHGDITIEIKSDTLSEAISIRDFLVTFKQPLARQ--------------EEQVRMVRQFHFHGWPEV-GIPTEGKGMIDLIAAVQKQQQQT-GNH-----------------------------------------------PITVHCSAGAGRTGTFIALSNILERV-----------------KAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49446-1", "uniprot_id": "PTPRE_MOUSE", "id": "P49446-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPFCPLLLASFSLSLARAGQGNDTTP----------------------------------------------------------------------------------------------------------------------------TESNWTSTTAGPPDP----------GASQPLLTWLLLP--LLLLLFL-------------------------------------------------------------------------------------LAAYFFRFRKQRKAVVSSNDK------------------------KMPNGILEEQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQRVMLLSRSPSGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKFFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGH-------------------IQGTFELANKEENREKNRYPNILPN------------------------------------DHCRVILSQVDGIPCSDYINASYID------GYKEKNKFIAAQGPKQETVNDFWRMVWE-----QRSATIVMLTNLKERKEEKCYQYWP--DQGCWTYGNIR--------------------------------------------------------VCVEDCVVLVDYTIRKFCIHPQLPDSCKAP-RLVSQLHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHS---EQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYG----------------------------------------------------------------------------------------DTELDVSSLERHLQTLHSTATHFDKIGLEEEFRKLTNVRIMK--ENMRTGNLPANMKKARVIQIIPYDF-----------NRVILSMKRGQ-------------------------------------------------------------------------------EFTDYINASFIDGYR-QKDYFMATQGPLAHTVEDFWRMVWEWK---SHTIVMLTEVQEREQD-KCYQYWPT----------------EGSVTHGDITIEIKSDTLSEAISVRDFLVTFKQPLARQ--------------EEQVRMVRQFHFHGWPEV-GIPAEGKGMIDLIAAVQKQQQQT-GNH-----------------------------------------------PITVHCSAGAGRTGTFIALSNILERV-----------------KAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23469-1", "uniprot_id": "PTPRE_HUMAN", "id": "P23469-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLCPLLLVGFSLPLARALRGNETT-----------------------------------------------------------------------------------------------------------------------------ADSNETTTTSGPPDP----------GASQPLLAWLLLPLLLLLLVLL-------------------------------------------------------------------------------------LAAYFFRFRKQRKAVVSTSDK------------------------KMPNGILEEQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQRVMLLSRSPSGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGH-------------------IQGTFELANKEENREKNRYPNILPN------------------------------------DHSRVILSQLDGIPCSDYINASYID------GYKEKNKFIAAQGPKQETVNDFWRMVWE-----QKSATIVMLTNLKERKEEKCHQYWP--DQGCWTYGNIR--------------------------------------------------------VCVEDCVVLVDYTIRKFCIQPQLPDGCKAP-RLVSQLHFTSWPDFGVPFT----------------------------------PIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHA---EQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYG----------------------------------------------------------------------------------------DTELDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRIMK--ENMRTGNLPANMKKARVIQIIPYDF-----------NRVILSMKRGQ-------------------------------------------------------------------------------EYTDYINASFIDGYR-QKDYFIATQGPLAHTVEDFWRMIWEWK---SHTIVMLTEVQEREQD-KCYQYWPT----------------EGSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQ--------------EEQVRVVRQFHFHGWPEI-GIPAEGKGMIDLIAAVQKQQQQT-GNH-----------------------------------------------PITVHCSAGAGRTGTFIALSNILERV-----------------KAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5P8-1", "uniprot_id": "A0A8M2B5P8_DANRE", "id": "A0A8M2B5P8-1", "name": "Receptor-type tyrosine-protein phosphatase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVLFLVSAALISN---------------------------------------------------------------------------------------------------------------------------------------SSSHGNLTTESPAP----------QGSHVLASGLVTS-LLLVIFLL-------------------------------------------------------------------------------------LVAYILRFREQRKDLVTSVDK------------------------KLPNGFLEDQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTVVLLPRSPSPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRYFPIPLDSLEEEFRLRMADDGKLFREEFNSLPCGF-------------------GCGTFEEASREENREKNRYPNILPY------------------------------------DHSRVLLSHIDGYMGSDYINASYID------GYREKNKFIAAQGPKPETVGDFWRMVWE-----HKCATIVMLTNTRERKEEKCYQYWP--EQGCWIYGCVR--------------------------------------------------------VAMEDFTVLVDYTIRKFCVQHHAAEGCRPP-RLVTQLHFTSWPDFGVPLS----------------------------------PIGMLKFLKKVKSVNPAHAGPIIVHCSAGVGRTGTFIVIDAMMDMMHA---EGRVDVFGFVSRIRKQRCQLIQTDMQYSFIYQALLEHYLFG----------------------------------------------------------------------------------------DTELDIASLEGHLHKLHNTHTNMDRVGLEEEFRKLTNVRIMK--ENMRTGNLPANMRKNRVLQIIPYDF-----------NRVILSMKRGQ-------------------------------------------------------------------------------EFTDYINASFIDGYR-QKDYFIATQAPLAHTVQDFWRMVWEWK---CHSIVVLTELKEREQE-KCVRYWPA----------------EGSVSFGDYVLELKRDTLCETFSIRDMLLSYAS-------------------EKQTRLVRQFHFHGWPEI-GIPSDGKGMIDIIAAVQKQQQQS-GNN-----------------------------------------------PIVVHCSAGAGRTGTFIALSNILERV-----------------KAEGLLDVFQTVKSLRTQRPHMVQTVEQYDFCYRVVQDFVDIYSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QJB7-1", "uniprot_id": "A0A8M9QJB7_DANRE", "id": "A0A8M9QJB7-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVLFLSVTTPQV---------------------------------------------------------------------------------------------------------------------------------------TTNATENNHGDPGP----------FNTHILSILLGLS-VLLLFLGL-------------------------------------------------------------------------------------LTWYCLRLKNQRKAVITAVDK------------------------KVPNGILEEQEEYIDVDVDVDMDMDMDEDEDEDDLG-------------------------------------------------------------------------------------------------------------------------------------------------------------WPSEEQQTVVLLPRSPSTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTYLPIPVDNLEEEYRIRSADDGKLFREEYSSLPGGS-------------------IQGTCEEANKEENKEKNRYPNILPY------------------------------------DQSRVILTPMDGVTCSDYINASYID------GYKDKNKFIAAQGPKQDTTADFWRMIWE-----QKSSTIVMLTNLKERKEDKCYQYWP--DQGCWTYGNVR--------------------------------------------------------VAVEDFTVLVDYTIRKFCVQYQASDGSKSP-RLVTQLHFTSWPDFGVPFS----------------------------------PIGMLKFLKKVKQVNPSYAGPIVVHCSAGVGRTGTFIVIDAMIDMMHT---EQKVDVFGFVSRIREQRSQLIQTDLQYSFVYQALLEYFLYG----------------------------------------------------------------------------------------DTELDVSSLEGHLQKLHNTNAPLDRVGLEEEFKKLTNMRIMK--ENMRTGNLPANMKKNRVLQIIPYDF-----------NRVILSMKRGQ-------------------------------------------------------------------------------EFTDYVNASFIDGYR-QKDYYIATQGPLVHTVDDFWRMAWEWK---CHSIVMLTELQERDQD-KCFQYWPS----------------EDSVTYGEFSVEIKGDTLCETFSLRDLVLTHTP-------------------EKQTRLVRHFHFHGWPEI-GIPAEGKGMIDIIAAVQKQQQQS-GNH-----------------------------------------------PIIVHCSAGAGRTGTFIALSNILERV-----------------KAEGLLDVFQTVKSLRMQRPHMVQTVEQYDFCYRVVQDFVDIFSDYANFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06800-4", "uniprot_id": "PTPRC_MOUSE", "id": "P06800-4", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "------------------------------------------------------------------MTMGLWLKLLAFGFALLDTEVFVTGQTPTPSDE-LSTTENALLLPQSDPLPARTTESTPPSISE------------------------------RGNGSSETTYHP----------------------------------GVLSTLLPHLSPQPDSQTPSAGGADTQTFSS---------------QADNPTLTPAPGGGTDPPGVPGERTVPGTIPADTAFPVD-TPSLARNSSAASPTHTSNVSTTDISSGASLTTLTPSTLG-LASTDPPSTTIAT-TTKQTCAAMFGNITVNYTYESSNQTFKADLKDVQNAKCGNEDCEN-VLNNLEECSQIKNISVS--NDSC-APATTIDLYVPPGTDKFSLHDCTPKEKANTSICLEWKTKNLDFRKCNSDNISYVLHCEPE-------NNTKCIRRNTFIPERCQLDNLRAQTNYTCVAEILYR-GVKLVKNVINVQTDLGIPET-PKPSCGDPAARKTLVSWPEPVSKPESASKPHGYVLCYKNN-SEKCKSLPN-------NVTSFEVESLKPYKYYEVSLLAYVNGKIQRNGTAEKCNFHTKADRPDKVNGMKTSRPTDNSINVTCGPPYETNGPKTFYILVVRSGGS--------------------------------------------------FVTKYNKTNCQFYVDNLYYSTDYEFLVSFHNGVYEGDSVIRNESTNFNAKALIIFLVFLIIVTS---------------------------------------------------------------------------------------IALLVVLYKIYDLRKKRSSNLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQQELVERDDEKQLMD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEPIHSDILLETYKRKIADEGRLFLAEFQSIPRVF-------------------SKFPIKDARKPHNQNKNRYVDILPY------------------------------------DYNRVELSEINGDAGSTYINASYID------GFKEPRKYIAAQGPRDETVDDFWRMIWE-----QKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFKDIV--------------------------------------------------------VTINDHKRCPDYIIQKLNVAHKKE---KATGREVTHIQFTSWPDHGVPED----------------------------------PHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEA---EGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFG----------------------------------------------------------------------------------------ETEVNLSELHSCLHNMKKRDPPSDPSPLEAEYQRLPSYRSWR---TQHIGNQEENKKKNRNSNVVPYDF-----------NRVPLKHELEMSKESEPE------------------------------------------------------------SDESSDDDSDSEETSKYINASFVMSYW-KPEMMIAAQGPLKETIGDFWQMIFQRK---VKVIVMLTELVNGDQE-VCAQYWG-----------------EGKQTYGDMEVEMKDTNRASAYTLRTFELRHSK-------------------RKEPRTVYQYQCTTWKGE-ELPAEPKDLVSMIQDLKQKLP-KASPEGMKYH---------------------------------------KHASILVHCRDGSQQTGLFCALFNLLESA-----------------ETEDVVDVFQVVKSLRKARPGVVCSYEQYQFLYDIIASIYPAQNGQVKKTNSQ-DKIEFHNEVDGGKQDANCVRPDGPLNKAQEDSRGVGTPEPTNSAEEPEHAANGSASPAPTQSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04157-1", "uniprot_id": "PTPRC_RAT", "id": "P04157-1", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "--------------------------------------------------------------------MYLWLKLLAFSLALLGPEVFVTGQG-TTDDG-LDTTE-IVLLPQTDPLPARTTEFTPPSISE------------------------------RGNGSSETTYLP----------------------------------GFSSTLMPHLTPQPDSQTPSARGADTQTLSS---------------QADLTTLTAAPSGETDPPGVPEESTVP------ETFPGG-TPILARNSTAPSPTHTSNVSTTDISSGANLTTPAPSTLG-FASNTTTSTEIATPQTKPSCDEKFGNVTVRYIYDDSSKNFNANLEGDKKPKCEYTDCEK-ELKNLPECSQ-KNVTLS--NGSC-TPDKIINLDVPPGTHNFNLTNCTPDIEANTSICLEWKIKNK--FTCDIQKISYNFRCTPE-------MKTFALDKHGTL----WLHNLTVRTNYTCAAEVLYN-NVILLKQDRRVQTDFGTPEMLPHVQCKNSTNSTTLVSWAEPAS------KHHGYILCYKKTPSEKCENLAN-------DVNSFEVKNLRPYTEYTVSLFAYVIGRVQRNGPAKDCNFRTKAARPGKVNGMKTSRASDNSINVTCNSPYEINGPEARYILEVKSGGS--------------------------------------------------LVKTFNQSTCKFVVDNLYYSTDYEFLVYFYNGEYLGDPEIKPQSTSYNSKALIIFLVFLIIVTS---------------------------------------------------------------------------------------IALLVVLYKIYDLRKKRSSNLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQQELVERDEEKQLIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDPIHSDLLLETYKRKIADEGRLFLAEFQSIPRVF-------------------SKFPIKDARKSQNQNKNRYVDILPY------------------------------------DYNRVELSEINGDAGSTYINASYID------GFKEPRKYIAAQGPRDETVDDFWKMIWE-----QKATVIVMVTRCEEGNRNKCAEYWPCMEEGTRTFRDVV--------------------------------------------------------VTINDHKRCPDYIIQKLSIAHKKE---KATGREVTHIQFTSWPDHGVPED----------------------------------PHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLESLEA---EGKVDVYGYVVNLRRQRCLMVQVEAQYILIHQALVEYNQFG----------------------------------------------------------------------------------------ETEVNLSELHSCLQNLKKRDPPSDPSPLEAEYQRLPSYRSWR---TQHIGNQEENKKKNRSSNVVPYDF-----------NRVPLKHELEMSKESEAE------------------------------------------------------------SDESSDEDSDSEETSKYINASFVMSYW-KPEMMIAAQGPLKETIGDFWQMIFQRK---VKVIVMLTELMSGDQE-VCAQYWG-----------------EGKQTYGDMEVMLKDTNKSSAYILRAFELRHSK-------------------RKEPRTVYQYQCTTWKGE-ELPAEPKDLVTLIQNIKQKLP-KSGSEGMKYH---------------------------------------KHASILVHCRDGSQQTGLFCALFNLLESA-----------------ETEDVVDVFQVVKSLRKARPGMVGSFEQYQFLYDIMASIYPTQNGQVKKANSQ-DKIEFHNEVDGAKQDANCVQPADPLNKAQEDSKEVGASEPASGSEEPEHSANGPMSPALTPSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08575-3", "uniprot_id": "PTPRC_HUMAN", "id": "P08575-3", "name": "Receptor-type tyrosine-protein phosphatase C", "aln": "------------------------------------------------------------------MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFE------------------------------RENDFSETTTSLSPDNTSTQVSPDSLDNASAF-----------NTTGVSSVQTPHLPTHADSQTPSAG-TDTQTFSG---------------SAANAKLNPTP-GSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKN-ASVSIS--HNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIET--FTCDTQNITYRFQCG-----------NMIFDNKEIK-----LENLEPEHEYKCDSEILYN-NHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQR------SFHNFTLCYIKETEKDCLNLDK-------NLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNT--------------------------------------------------LVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTS---------------------------------------------------------------------------------------IALLVVLYKIYDLHKKRSCNLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQQELVERDDEKQLMN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVF-------------------SKFPIKEARKPFNQNKNRYVDILPY------------------------------------DYNRVELSEINGDAGSNYINASYID------GFKEPRKYIAAQGPRDETVDDFWRMIWE-----QKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVV--------------------------------------------------------VKINQHKRCPDYIIQKLNIVNKKE---KATGREVTHIQFTSWPDHGVPED----------------------------------PHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEA---ENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFG----------------------------------------------------------------------------------------ETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWR---TQHIGNQEENKSKNRNSNVIPYDY-----------NRVPLKHELEMSKESEHD------------------------------------------------------------SDESSDDDSDSEEPSKYINASFIMSYW-KPEVMIAAQGPLKETIGDFWQMIFQRK---VKVIVMLTELKHGDQE-ICAQYWG-----------------EGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSK-------------------RKDSRTVYQYQYTNWSVE-QLPAEPKELISMIQVVKQKLPQKNSSEGNKHH---------------------------------------KSTPLLIHCRDGSQQTGIFCALLNLLESA-----------------ETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35239-1", "uniprot_id": "PTN9_MOUSE", "id": "O35239-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPATAPRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMAPELTPEEEQATKQFLEEINKWTVQYNVS-----------------------PLSWNVAVKFLMARKFDVLRAVELF------------------------------------HCYRETRRKEG----IVKLKPHEEP------LRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLG----GYVKIDLATWNFQFLPQVNGHPD---------------------------------------------------------------------------------P---FDEIILSSLPPAL------------------------------------------------------------------------------------------------------------------DWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGT---FHCSMSPGNLEKNRYGDVPCLDQ-----------TRVKLTKRSGHT-------------------------------------------------------------------------------QTDYINASFMDGYK-QKNAYIGTQGPLENTYRDFWLMVWEQK---VLVIVMTTRFEEGGRR-KCGQYWPLEK--------------DSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTE-------------------ERQKRQVTHFQFLSWPDY-GVPSSAASLIDFLRVVRNQQSMAVGNLGARSKG------------------------------------QCPEPPIVVHCSAGIGRTGTFCSLDICLAQL-----------------EELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVP----SGHSLLAMDGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641Z2-1", "uniprot_id": "PTN9_RAT", "id": "Q641Z2-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPATAPRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMAPELTPEEEQATKQFLEEINKWTVQYNVS-----------------------PLSWNVAVKFLMARKFDVLRAVELF------------------------------------HCYRETRRKEG----IVKLKPHEEP------LRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLG----GYIKIDLATWNFQFLPQVNGHPD---------------------------------------------------------------------------------P---FDEIILFSLPPAL------------------------------------------------------------------------------------------------------------------DWDSVHVPGPHAMTIQELVDYVNTRQKQGIYEEYEDIRRENPVGT---FHCSMSPGNLEKNRYGDVPCLDQ-----------TRVKLTKRSGHT-------------------------------------------------------------------------------QTDYINASFMDGYK-QKNAYIGTQGPLENTYRDFWLMVWEQK---VLVIVMTTRFEEGGRR-KCGQYWPLEK--------------DSRIQFGFLTVTNLGVENMNHYKKTTLEIHNTE-------------------ERQKRQVTHFQFLSWPDY-GVPSSAASLIDFLRVVRSQQSMAVGSLGARSKG------------------------------------QCPEPPIVVHCSAGIGRTGTFCSLDICLAQL-----------------EELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVP----SGHSLLAMDGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43378-1", "uniprot_id": "PTN9_HUMAN", "id": "P43378-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPATAPRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMAPELTPEEEQATKQFLEEINKWTVQYNVS-----------------------PLSWNVAVKFLMARKFDVLRAIELF------------------------------------HSYRETRRKEG----IVKLKPHEEP------LRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLG----GYVKIDLATWNFQFLPQVNGHPD---------------------------------------------------------------------------------P---FDEIILFSLPPAL------------------------------------------------------------------------------------------------------------------DWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGT---FHCSMSPGNLEKNRYGDVPCLDQ-----------TRVKLTKRSGHT-------------------------------------------------------------------------------QTDYINASFMDGYK-QKNAYIGTQGPLENTYRDFWLMVWEQK---VLVIVMTTRFEEGGRR-KCGQYWPLEK--------------DSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTE-------------------ERQKRQVTHFQFLSWPDY-GVPSSAASLIDFLRVVRNQQSLAVSNMGARSKG------------------------------------QCPEPPIVVHCSAGIGRTGTFCSLDICLAQL-----------------EELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVS----SGQNLLAVESQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W323-1", "uniprot_id": "Q9W323_DROME", "id": "Q9W323-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQTQWNKDRQEDRNNNSGSRSEQDSGCHRRLFLCIAKAVKQFIDLCNNLGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCSTTTATSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVRRHISHTTAVKFLYARKFDIPRAVSLY------------------------------------EQHEQIRLKEY----LYNIDPDVEP------LRSELQTGKFTILPARTSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLG----GTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEP---NENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGG-----------------------------------------EFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGT---FLHARMRANLTKNRYTDVLCYDH-----------SRVVLAHEDGDE-------------------------------------------------------------------------------PSDYINANFVDGYK-QKNAYISTQGPLPKTSQDFWRMIWEQH---CLVIVMTTRVMERGRV-KCGQYWEPTE--------------ESSLEFGDYHVRTISVECNEDYMVASLELRNIK-------------------TDEIRNVSHWQFTSWPDY-GVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAG------------------------------------HPRGPPIVVHCSAGIGRTGTFITLDICISRL-----------------EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDEREPDSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35821-1", "uniprot_id": "PTN1_MOUSE", "id": "P35821-1", "name": "Tyrosine-protein phosphatase non-receptor type 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMEKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEEIDKAGNWAAIYQDIRHEASDFPCK---------------------------------VAKLPKNKNRNRYRDVSPF------------------------------------DHSRIKLHQED----NDYINASLIK------MEEAQRSYILTQGPLPNTCGHFWEMVWE-----QKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDTG------------------------------------------------------LKLTLISEDVKSYYTVRQLELENLT----TKETREILHFHYTTWPDFGVPES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASFLNFLFKVRESGSLSLEHGPIVVHCSAG----------------IGRSGTFCLAD-----------TCLLLMDKRKDP-------------------------------------------------------------------------------SSVDIKKVLLEMRR-FRMGLIQTADQLR-----FSYLAVIEG---AKFIMGDSSVQDQWKE-LSREDLDLPP--------------EHVPPP--PRPPKRTLEPHNGKCKELFSSHQWV-------------------SEETCGDEDSLAREE-GR-AQSSAMHSVSSMSPDTEVRRRMVGGGLQSAQAS------------------------------------VPTE---------------------EELSST-----------------EEEHKAHWPSHWKPFLVNVCMATLLATGAYLCYRVCFH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20417-1", "uniprot_id": "PTN1_RAT", "id": "P20417-1", "name": "Tyrosine-protein phosphatase non-receptor type 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMEKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEQIDKAGNWAAIYQDIRHEASDFPCR---------------------------------IAKLPKNKNRNRYRDVSPF------------------------------------DHSRIKLHQED----NDYINASLIK------MEEAQRSYILTQGPLPNTCGHFWEMVWE-----QKSRGVVMLNRIMEKGSLKCAQYWPQKEEKEMVFDDTN------------------------------------------------------LKLTLISEDVKSYYTVRQLELENLA----TQEAREILHFHYTTWPDFGVPES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASFLNFLFKVRESGSLSPEHGPIVVHCSAG----------------IGRSGTFCLAD-----------TCLLLMDKRKDP-------------------------------------------------------------------------------SSVDIKKVLLEMRR-FRMGLIQTADQLR-----FSYLAVIEG---AKFIMGDSSVQDQWKE-LSHEDLEPPP--------------EHVPPP--PRPPKRTLEPHNGKCKELFSNHQWV-------------------SEESCEDEDILAREE-SR-APSIAVHSMSSMSQDTEVRKRMVGGGLQSAQAS------------------------------------VPTE---------------------EELSPT-----------------EEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18031-1", "uniprot_id": "PTN1_HUMAN", "id": "P18031-1", "name": "Tyrosine-protein phosphatase non-receptor type 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMEKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEQIDKSGSWAAIYQDIRHEASDFPCR---------------------------------VAKLPKNKNRNRYRDVSPF------------------------------------DHSRIKLHQED----NDYINASLIK------MEEAQRSYILTQGPLPNTCGHFWEMVWE-----QKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTN------------------------------------------------------LKLTLISEDIKSYYTVRQLELENLT----TQETREILHFHYTTWPDFGVPES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASFLNFLFKVRESGSLSPEHGPVVVHCSAG----------------IGRSGTFCLAD-----------TCLLLMDKRKDP-------------------------------------------------------------------------------SSVDIKKVLLEMRK-FRMGLIQTADQLR-----FSYLAVIEG---AKFIMGDSSVQDQWKE-LSHEDLEPPP--------------EHIPPP--PRPPKRILEPHNGKCREFFPNHQWV-------------------KEETQEDKDCPIKEEKGS-PLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAA------------------------------------SPAK---------------------GEPSLP-----------------EKD-EDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17706-1", "uniprot_id": "PTN2_HUMAN", "id": "P17706-1", "name": "Tyrosine-protein phosphatase non-receptor type 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTTIERE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEELDTQRRWQPLYLEIRNESHDYPHR---------------------------------VAKFPENRNRNRYRDVSPY------------------------------------DHSRVKLQNAE----NDYINASLVD------IEEAQRSYILTQGPLPNTCCHFWLMVWQ-----QKTKAVVMLNRIVEKESVKCAQYWP-TDDQEMLFKETG------------------------------------------------------FSVKLLSEDVKSYYTVHLLQLENIN----SGETRTISHFHYTTWPDFGVPES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASFLNFLFKVRESGSLNPDHGPAVIHCSAG----------------IGRSGTFSLVD-----------TCLVLMEKGDD----------------------------------------------------------------------------------INIKQVLLNMRK-YRMGLIQTPDQLR-----FSYMAIIEG---AKCIKGDSSIQKRWKE-LSKEDLSPAF--------------DHSP-------NKIMTEKYNG-------NRIGL-------------------EEEKLTGDR-------CT-GLSSKMQDTMEENSESALRKRIRE-DRKATTAQ------------------------------------KVQQ---------------------MKQRLN-----------------ENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29351-1", "uniprot_id": "PTN6_MOUSE", "id": "P29351-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVR-WFHRDLSGPDAETLLKGRGVPGS--------------------------FLARPSRKNQGDFSLSVRVD-----------------------------------DQVTHIRIQNSGDFYDLYGGEKFAT------LTELVEYYTQQQGILQ-----------------DRDGTIIHLKYPLNCSDPTSERWYHGHISGGQAESLLQ------------------------------------------------------------AKGEPWTFLVRESLSQPGD--------FVLSVLNDQPKAGPGSPLR----------------------------------------------------VTHIKVMCEGGRYTVGGSETFDSLTDLVEH---FKKTGIEEASGAFVYLRQPYYATR----------------------------------------------------------------------------------------------------------VNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKN-LHQRLEGQRPENKSKNRYKNILPFDH-----------SRVILQGRDSNIPGSD-------------------------------------------------------------------------YINANYVKNQLLGPDE-NSKTYIASQGCLDATVNDFWQMAWQEN---TRVIVMTTREVEKGRN-KCVPYWPEV---------------GTQRVYGLYSVTNSREHDTAEYKLRTLQISPLD----N--------------GDLVREIWHYQYLSWPDH-GVPSEPGGVLSFLDQINQRQESLPHAGP-----------------------------------------------IIVHCSAGIGRTGTIIVIDMLMESIST--------------KGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITYPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81718-1", "uniprot_id": "PTN6_RAT", "id": "P81718-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSRGWFHRDLSGPDAETLLKGRGVPGS--------------------------FLARPSRKNQGDFSLSVRVD-----------------------------------DQVTHIRIQNSGDFYDLYGGEKFAT------STELVEYYTQQQGILQ-----------------DRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAESLLQ------------------------------------------------------------AKGEPWTFLVRESLSQPGD--------FVLSVLNDQPKAAPGSPLR----------------------------------------------------VTHIKVMCEGGRYTVGGSETFDSLTDLVEH---FKKTGIEEASGAFVYLRQPYYATR----------------------------------------------------------------------------------------------------------VNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEAKN-LHQRLEGQRPENKSKNRYKNILPFDH-----------SRVILQGRDSNIPGSD-------------------------------------------------------------------------YINANYVKNQLLGPDE-NSKTYIASQGCLDATVNDFWQMAWQEN---TRVIVMTTREVEKGRN-KCVPYWPEV---------------GTQRVYGLYSVTNCKEHDTAEYKLRTLQISPLD----N--------------GDLVREIWHYQYLSWPDH-GVPSEPGGVLSFLDQINQRQESLPHAGP-----------------------------------------------IIVHCSAGIGRTGTIIVIDMLMESVST--------------KGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGNITYPPALRSAHAKASRTSSKHKEEVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRNISLTPCRGLRWADRDL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29350-1", "uniprot_id": "PTN6_HUMAN", "id": "P29350-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVR-WFHRDLSGLDAETLLKGRGVHGS--------------------------FLARPSRKNQGDFSLSVRVG-----------------------------------DQVTHIRIQNSGDFYDLYGGEKFAT------LTELVEYYTQQQGVLQ-----------------DRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQ------------------------------------------------------------AKGEPWTFLVRESLSQPGD--------FVLSVLSDQPKAGPGSPLR----------------------------------------------------VTHIKVMCEGGRYTVGGLETFDSLTDLVEH---FKKTGIEEASGAFVYLRQPYYATR----------------------------------------------------------------------------------------------------------VNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKN-LHQRLEGQRPENKGKNRYKNILPFDH-----------SRVILQGRDSNIPGSD-------------------------------------------------------------------------YINANYIKNQLLGPDE-NAKTYIASQGCLEATVNDFWQMAWQEN---SRVIVMTTREVEKGRN-KCVPYWPEV---------------GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLD----N--------------GDLIREIWHYQYLSWPDH-GVPSEPGGVLSFLDQINQRQESLPHAGP-----------------------------------------------IIVHCSAGIGRTGTIIVIDMLMENIST--------------KGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35831-1", "uniprot_id": "PTN12_MOUSE", "id": "P35831-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLS-------------TKYRTEKIYPTATGEKEENVKKNRYKDILPFD------------------------------------HSRVKLTLKTPSQDSDYINANFIK------GVYGPKAYVATQGPLANTVIDFWRMIWEYN-----VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFK-------------------------------------------------------ISCENEQARTD-YFIRTLLLEFQN------ESRRLYQFHYVNWPDHDVPSS----------------------------------FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLY--------------------------EIHGAQKIADG-NEITTGTMVSSIDS----EKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMASP------EQHPADLNRSYDKSADPMGK-----------SESAIEHIDKKLERNLS--------------------------------------------------FEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASSSVVDRTSKPQELSAGALKVDDVSQNSCADCSAAHSHRAAESSEESQSNSHTPPRPDCLPLDK--------------KGHVTWSLHGPENATPVPDSPDGKSPDNHSQTLKTVSS----------TPNSTAEEEAHDLTEHHNSSPLLKAPLSFTNPLHSDDSDSDGGSSDGAVTRNKTSI------------------------------------STASATVSPASSAESACTRRVLPMSIARQEVA-----------------GTPHSGAEKDADVSEESPPPLPERTPESFVLA---DMPVRPEWHELPNQEWSEQRESEGLTTSGNEK--HDAGGIHTEASADSPPAFSDKKDQITK-----SPAEVTDIGFGNRCGKPKGPREPPSEWT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZN71-1", "uniprot_id": "A0A8I5ZN71_RAT", "id": "A0A8I5ZN71-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLS-------------TKYRTEKIYPTATGEKEENVKKNRYKDILPFD------------------------------------HSRVKLTLKTPSQDSDYINANFIK------GVYGPRAYVATQGPLANTVIDFWRMIWEYN-----VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFK-------------------------------------------------------ISC---VICTY-ILLLTECLFFMK------ESRRLYQFHYVNWPDHDVPSS----------------------------------FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLY--------------------------EIHGAQKITDG-NEISTGNMVSSIDS----EKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMASP------EQPPTDLNRNYDKSADLMGR-----------SESAVEHTDKKLEQNLS--------------------------------------------------FEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASSSVVDKSSKPQELSSGDLKVHDVSQNSCADCSASHLDNAPESSEESQ-NSHTPPRPDCLPLDK--------------KGHVTWSLHGPENATPVSDSP-----DNHSQTLKTVSS----------TPNSTAEEESHDLTEHHNSSPLPRAPLSFTNPLHSDDSDSDEGNSDGAVTKNKTSI------------------------------------STASATVSPASSTESACTRRVLPMSIARQEMA-----------------GRRHSGAEKDADVSEESPPPLPERTPESFVLA---DMPIRSDWHELPSQECSEHRESEGLITSGNDK--HDAGVSHTAACS---PTFSDKKEEITE-----SLTEVTDIGFGNRCGKPKGPRDPPSEWT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05209-1", "uniprot_id": "PTN12_HUMAN", "id": "Q05209-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLS-------------TKYRTEKIYPTATGEKEENVKKNRYKDILPFD------------------------------------HSRVKLTLKTPSQDSDYINANFIK------GVYGPKAYVATQGPLANTVIDFWRMIWEYN-----VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFK-------------------------------------------------------ISCEDEQARTD-YFIRTLLLEFQN------ESRRLYQFHYVNWPDHDVPSS----------------------------------FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLY--------------------------EIHGAQKIADGVNEINTENMVSSIEP----EKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSS------EQHSADLNRNYSKSTELPGK-----------NESTIEQIDKKLERNLS--------------------------------------------------FEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSS-DLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDE--------------KGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSL----------TPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNI------------------------------------STASATVSAATSTESISTRKVLPMSIARHNIA-----------------GTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISE-----NPTEATDIGFGNRCGKPKGPRDPPSEWT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29352-1", "uniprot_id": "PTN22_MOUSE", "id": "P29352-1", "name": "Tyrosine-protein phosphatase non-receptor type 22", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQREILQQLLKEAQKKKLNSEEFASEFLKLKRQS-------------TKYKADKIYPTTVAQRPKNIKKNRYKDILPYD------------------------------------HSLVELSLLTSDEDSSYINASFIK------GVYGPKAYIATQGPLSTTLLDFWRMIWEYR-----ILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFS-------------------------------------------------------ISCEAEKKKSD-YKIRTLKAKFNN------ETRIIYQFHYKNWPDHDVPSS----------------------------------IDPILQLIWDMRCYQEDDCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHMDVISDNHLGR-------------------EIQAQCSIPEQSLTVEADSCPLDLPKNAMRDVKTTNQHSKQGAEAESTGGSSLGLRTSTMNAEEELVLHSAKSSPSFNCLELNCGCNNKAVITRNGQARAS----PVVGEPLQKYQSLDFGSMLFGS---------CPSALPINTADRYHNSKGP-------------------------------------------------VKRTKSTPFELIQQRKTNDLAVGDGFSCLESQLHEHYSLRELQVQRVAHVSSEELNYSLP-----GACDASCVPRHSPGALRVHLYTSLAEDPYFSS--------SPPNSADSKMSFDLPEKQDGATSPGALLPASSTTSFFYSNPHDS---LVMNTLTSFSPPLNQETAVEAPSRRTDDEIPPPLPERTPESFIVVEEAG-EPSPRVTESLP--------------------------------------LVVTFGASPECSGTSE-MKSHDSVGFTPSKNV-----------------KLRSPKSDRHQD-GSPPPPLPERTLESFFLADEDCIQAQAVQTSSTSYPETTENSTSSKQTLRTPGKSFTRSKSLKIFRNMKKSVCNSSSPSKPTERVQPKNSSSFLNFGFGNRFSKPKGPRNPPSAWNM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXN3-1", "uniprot_id": "A0ABK0LXN3_RAT", "id": "A0ABK0LXN3-1", "name": "protein-tyrosine-phosphatase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVARRLLLYGMDQREILQQLLKEAQKKKINREEFANEFLKLKRQS-------------TKYKADKIYPTTVAQRPKNIKKNRYKDILPYD------------------------------------HSLVELSLLTSDEDSSYINASFIK------GVYGPRAYIATQGPLSTTLLDFWRMIWEYR-----VLVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFS-------------------------------------------------------ISCETEKKKSD-YKIRTLKAKFNS------ETRIVYQFHYKNWPDHDVPSS----------------------------------IDPILQLIWDMRCYQEDDCVPLCIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHVDIISDNHRER-------------------EIQAECSIPEQKLTIEADSYPLDFPKNAVRDAKMTNQQSKQGAEAESTEVSSFGLRTSKISAKEELVLHS-KSSPSFDCLELNCECN-KAVITRNGQARAS----LVVGEPLQKYQSLDFGSILFGS---------CPSALPINTASRCHNSKGP-------------------------------------------------VKRTKSTPFELIQQRKTNELAVEDGSSCLESQLLEHG-LMELQAQKVAHASSEELNYSLPRACERPACDASCVPQDGPGALREHLCMSLAEDPYFSS--------SPPNSAGSKMSFDLPEKQDGATSPGAQLPASSAASSSYSNPRDS---LMESTLTSFPPPINQETAIEATSARTDDEIPPPLPERTPESFIVAEAAG-EPSPSITESLP--------------------------------------LAGKSGVTLECGGTSE-SQSHDLVAFTSSKNV-----------------ELGSPKSDQHQD-GSPPPPLPERTLESFFLADEDCIQAQPMKPSSISYPETTEISTSSKQTLKTPGKSFTRSKSLKIFRNMKKSVCNSPSPSKPTECVQPKNSSSFLNFGFGTRFSKPKGPRNPPSTWNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2R2-1", "uniprot_id": "PTN22_HUMAN", "id": "Q9Y2R2-1", "name": "Tyrosine-protein phosphatase non-receptor type 22", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQS-------------TKYKADKTYPTTVAEKPKNIKKNRYKDILPYD------------------------------------YSRVELSLITSDEDSSYINANFIK------GVYGPKAYIATQGPLSTTLLDFWRMIWEYS-----VLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFS-------------------------------------------------------VSCEAEKRKSD-YIIRTLKVKFNS------ETRTIYQFHYKNWPDHDVPSS----------------------------------IDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSGT-------------------ESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQ---QRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAF----PIVGEPLQKHQSLDLGSLLFEG---------CSNSKPVNAAGRYFNSKVP-------------------------------------------------ITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC-FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSS--------WPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDS---LSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRTPESFIVVEEAG-EFSPNVPKSLSSA------------------------------------VKVKIGTSLEWGGTSEPKKFDDSVILRPSKSV-----------------KLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTWNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IKC5-1", "uniprot_id": "A0AC58IKC5_DANRE", "id": "A0AC58IKC5-1", "name": "protein-tyrosine-phosphatase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAQMHILRNQLDLIAIKEAEDETAENGFAGEFLKLKRQS-------------TKYRAERTYPTTAADKQDNVKKNRYKDIVPFD------------------------------------HSRVKLSLFTSKNDTDYINASFIK------GVSGSKAYIATQGPLSNTVLDFWRMIWEYN-----IKVIVMVCREFEMGRKKCERYWPESKGDVFVCEAFT-------------------------------------------------------ILYESDENKGD-YLTRTLKVTFKQ------ESRRLKQLHYVNWPDHGVPDS----------------------------------IPAILELLQEMRIYQDNEEIPICIHCSAGCGRTGALCAIDYTWNLLKRQIIPEDFSIFELVKGMRTQRPSVVQTKEQYELVYRTIKLLFERYLAALEAPSNKVPDSSSPAMLSSGSELSDISDFSDQEQTEHRNDEIRVDEYNHVMQNSASWQQPHSQPFSPEVMSNKLTPADLHNARCEWVQITDQSSFIAPVLQTDFTTCGSQKPDASTSLSTTSTQVSCSNYPISFVEELKPNKEHLEWVENQEASPVVKDHNTVIPSTLCLTVEDPYFGPESPPGSNNPSVLNCTAHEIWTEKSCFTIPSLALNNQALEMPKHDSNNKGGNTLSSDEESPPPLPERTPESFIMADETSGQSNNEKSETSELLTLVIPTSTSSESVNRDNPPSPVPPLPERTPESFEMAMDADLVQNVTQEKPQEVVMRVGKSL---EWSGQTNEGQTDMKRSWSRSKSLKLRMSLPASSTPLSPITITSHSPPPLLYKHTQDTFLDISTSHGQTFNSFQGKESLTPPLPERTPESFILHTEKVSNNSAPCQPVEAEQ------------------------------------YRGRVGTSSEWSGTSQ---PKSSVAHTWSRSK-----------------SVRAKGSKQEPFSVAPLSLPVSVTTPTIGQVEHQMGYSNQLAATGLLENQSNKGAEKTSLVSKARSKSFKLLKGKQKPKTAPPPVPSSASSTAPPQPVPTYGPVGLL-FSFGTRFGKPKGPRNKPETWV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61152-1", "uniprot_id": "PTN18_MOUSE", "id": "Q61152-1", "name": "Tyrosine-protein phosphatase non-receptor type 18", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRHTDLVRSFLEQLEARDYRE---GAILAREFSDIKARS-------------VAWKSEGVCSTKAGSRLGNTNKNRYKDVVAYD------------------------------------ETRVILSLLQEEGHGDYINANFIR------GIDGSQAYIATQGPLPHTLLDFWRLVWEFG-----VKVILMACQETENGRRKCERYWAREQE-PLKAGPFC-------------------------------------------------------ITLTKETTLNADITLRTLQVTFQK------EFRSVHQLQYMSWPDHGVPSS----------------------------------SDHILTMVEEARCLQGLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQDTS-----------------------------------------------------------------------------------------------------------------------------------------PHYQNLKENCAPICK-----------EAFSLRTSSALPATSRP------------------------------------------------------------------------------------------------------------------------------PGGVLRSISVPAPPTLPMAD------------------TYAVVQKRGASAG----------------------------------TGPGPRAPTSTDT--------PIYSQVAPRAQ------------------------------------------------------------------------------RPVAHTEDAQG-----------------TTALRRVPADQNSSGPD-----------------------------AYEEVTDGAQTGG-------------------------------------------------LGFNLRIGRPKGPRDPPAEWTRV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99952-1", "uniprot_id": "PTN18_HUMAN", "id": "Q99952-1", "name": "Tyrosine-protein phosphatase non-receptor type 18", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRSLDSARSFLERLEARGGRE---GAVLAGEFSDIQACS-------------AAWKADGVCSTVAGSRPENVRKNRYKDVLPYD------------------------------------QTRVILSLLQEEGHSDYINGNFIR------GVDGSLAYIATQGPLPHTLLDFWRLVWEFG-----VKVILMACREIENGRKRCERYWAQEQE-PLQTGLFC-------------------------------------------------------ITLIKEKWLNEDIMLRTLKVTFQK------ESRSVYQLQYMSWPDRGVPSS----------------------------------PDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNAS-----------------------------------------------------------------------------------------------------------------------------------------PHYQNIKENCAPLYD-----------DALFLRTPQALLAIPRP------------------------------------------------------------------------------------------------------------------------------PGGVLRSISVPGSPGHAMAD------------------TYAVVQKRGAPAG----------------------------------AGSGTQTGTGTGTGARSAEEAPLYSKVTPRAQ------------------------------------------------------------------------------RPGAHAEDARG-----------------TLPG-RVPADQSPAGSG-----------------------------AYEDVAGGAQTGG-------------------------------------------------LGFNLRIGRPKGPRDPPAEWTRV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAB3-1", "uniprot_id": "A1ZAB3_DROME", "id": "A1ZAB3-1", "name": "", "aln": "----------------------------------------------------------------MEATNWKQSHRRIHALILILWIAGVQGQTVGSLVAVSESQELAEKVEVTVVSTVYTLGFSIS-----------------------------------NEADYSIDKVICRNGSGSETEANAAHVCENLNPCTFYTSVVSFRSNVSGKPPPSDQTIYAYTEYKQPKTTVTSVVATANTIKVTWQTNDRACVESFGITAKATDYTKSFQLLNDKSSQTFVNLSACLTHTITLDTRNNASVVVDTDATDVDTQYAEPGDLVMNVTNLASGITMITWGDPSEKNCISNYVFKWQRNDCGTDQNQDTTTDVPSTETTNEIDYVTTTPMETTPDTPSDEVKCEWTDVSSDGKLREYLLTDLQGCDLYTFQVFINENSTAKASQTFTSAEKLVSAVYEPSPTAYPTQLHWTWFSPQNHPKCVANYSVTLTGPIQRSENKTMNVITEETFAIFDDLDPCGIYLVEIVPNQLNGSAGTKYQEQSTVGEDQPSVIQDPVVEAEAYSMEVSWKTPEYADLCIDGYRLSGWMEDDKLVEVEALSITTQNTTVVFDKNLLACQVYIIQIIPYTKENLDGQLRQVGVETKAAIVDYTKVKLEMKNAGSEFIDLIAFNADYNNSCPTIFALFTCNATTQVRNPYAERYVEGHSKQGFNASLSPLSPYATYVCKVILYNVAGPSEPVVDADMHTTTYFPEQPESVMLEKSTVSSLLFNWQPPTYTNGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETK--------------------------------------------------------------------GDPSVNFTGLAPAVRYMMQVAAQNDFGMGVYTEPVIG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITLPAVSDSVTQLTVLTQGPVN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNAVYEANVTITWKVPCKSNGDIEYFQLAFNGTRNNFAP-------------VSFERRVELDTGNKQGRMSYTETEMQPQFD-----------------------------------YTVEVSVKNRDVEQLSSSVPGSWQSPAG-LPTIPSDELIKQMRANVEETSNPTKTAIVRLPADIMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQEAGADG---------------------------------------------TGDCSLEYQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCN-----------------------------------------------------GPLLPDTDYNVVVRLFTASGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSG----------------------------------------------------------------------------------------QGIEDPFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELS-----YSASELGCHKNRYADIFPYDK-----------NRVILDIDAEG---------------------------------------------------------------------------------SDYINASFIDGHT-RKKEYIATQGPKPESVMDFWRMILQYN----VRVIVQVTQFREGNTIKCHEYYPYN--------------------VRGLTVTIKSKEVLELYDRTELTVVHDK-------------------YGLKEKVIHYYFKKWPDH-GVPEDPMHLIMFVKKVKAEKRPS-------------------------------------------------YSPIVVHCSAGVGRTGTFIGLDLIMQRLK-----------------SESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELVKHKIPRAALKMDGRPKSVTVPAIPSPKKVSFPDVDVGSEYVSSAPITDLDDGRPIVQLPSRFSGLRRNSPPGENDNPTSSSNM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1QQH6-1", "uniprot_id": "A0A8M1QQH6_DANRE", "id": "A0A8M1QQH6-1", "name": "protein-tyrosine-phosphatase", "aln": "---------------------------------------------------------------------MWRLRGPCRLGMLCLTLSALLIQPISCHPASHVETVRRGSSANQRERRASGEPYWAYSGTYGPRRWASAYPECGERNQSPVDILDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSIVLKNDYFVRGAGLPGRFKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMAVFFQVATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGSYYRYTGSLTTPPCSKVVEWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIFKSALMDAWMPETMASAADTETSRVCSSIPDNMKLHPLNRTALVLTWDRPSAVYHPPIVGFLVSYSWVKDEMPFEKTFTQSSEHSTRAVITLVSPDVLYLFRVQALCQRDQRSDFSQTLLFKANTTRIFEGTRIVKTGMPTVSPASSADMAPISSGSSTWTSAGLPFSFVSMATGMGPPSSGGQATVASVVTSTLLAGLGFSGSVISSLPGSFWPTHSTNTGPSPTQHPATPTAENSPSEDSTDTQNKLEEEEEHKKEDDEEEEEEEEEEEQRDEEKKKKGKDVTVKDKKQTVQKPTAPIPTSKHRDRERPDAESS----------------------TLTPAEVEEQVSGATERPDAEDSSKATWQDDNDMQIPSSSTESSKLSDEEKANWPYYINTERNSISTVSRDSVSSSSRMEWIIP--------------------------------------------------------------------------LMVVSALTLLCLIMLLAVLVYWRRFFQTAHFYIE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRNSPRVIHNDSFPIIST---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADDLEAMPVRQFIKHIMELHSNNRHGFSQEFDEVQHCTS-----------------EMKITAEHSNHPENKHKNRYINIVAYDHS----------------------------------RVKLQQLPGKDSKHSDYINANYVD------GYKRARAYIAAQGPLKSTFEDFWRMIWEQN-----TTVIVMITNLVEKGRRKCDQYWPSENSEVYGNIMVTLKS-----------------------------------------------------TKVYAYYTLRHFIVRNSKLKKGQKG--RQNERLVLQYHYTQWPDMGVPEYTLP----------------------------------VLKFISRSTVTHASSTGPVLVHCSAGVGRTGTYIVIDSMLKQIKD---RGSVNVLGFLKHIREQRNYLVQTEEQFIFIHDALMEAVLSK-----------------------------------------------------------------------------------------DTEVSAWQLHTYTNSLLTPSPTGHTRMDKHFKLLTQCNAHLA--ECLSGQKECNKEKNRTSAVLPTER-----------ARVALSPLPGLKG-------------------------------------------------------------------------------TDYINASYIMGYY-RSNEFIITQHPLPHTTTDFWRMIWDHN---AQVIVMLPDNLGLTED--EFVYWPSREEPMN----------CIAFTVTLINTDRLCLSNEEQLIIHDFILEATQ-------------------DDYVLEVRHFQCPNWPDPDASISSTFELINIIKEEAMTRDGP----------------------------------------------------TIVHDEFGAVSAGTFCALTTLSQQLE-----------------NESAVDVYQVAKMINLMRPGVFTEIEHYHYLYQAMLSLVSSKDFRFGFNYMDKFAGKADESNQAESMESLV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI81-1", "uniprot_id": "Q0KI81_DROME", "id": "Q0KI81-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------------------------------------------------------------MRVVGWLRGGLMLALAVMVTQARFIAKRETTGLEQAMASTSTDPDIVKAPRESGIGREPVAIKAESDMFSSQTNIEDEKSAKTVDQTETQTASPKENLNVKQTTAAFEKNESSNTTESHLNGAQVDPVKELKDTETSADTVKEESSTTTTSQLDQNPTNVTDKKSTEAQFKDERLSKEILSTTTEQILLTEKALQKYVVITNSPLRGEAQPEIKDKTSKSATSEKSTLPLKPVTIEVPSTTTEGVFNTTTTRSSDHGRSMQYSSTTEESSRSSPASVTPMKLIPLPMTSTPSSTTSTSTPLPTTAVSFASNENVIEESTSKSEVRQLPEKRAKFISENSTNAQQLTLPNTAEVWSLAGMKAVPKAPLTTTTSVPLLNHTDLANDIDMPLNKTELHKEKNLLDWMNIAMLPLTPENRTEFVVRTTLDATEGATQATTEALVEETHSKSDITVGLEQDNVTTARTMPSTPDPGSMDLNMTTTTVRTQQLEVPLVKKMSDAANAKLIEAVTEPQRETEAATEAATFVTLPEKLATFGITARVDSTQTELLNVTTAAAATESGEMSKANSTDTLSAMTSTTTTTARPMSVEHVTPEQDMEAATSLATTAATSSGTTEAAATSSTTAATPVVSEAATAAEASATSEATTAATLSVATTAASTTEIAMKATQISNIRDDNDDNSNDVIVATTKFPESEQAATTASVEPTTTSVSVRVAGEVSTSIRPEIIVTSTRNSTIVDTS-------------------------------------------------------------------------------------TSATSVATPTQTEIAQISNEVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEAVTVKTRDGLSDTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELRTAEKTDNAVNNSVAITESDLGALATAVETNPTTTN---------------SLLSDVSKLSKEHESSLETNNIGEAPPES-------------------------------TTPAAPATVAVATDESTAAPAATGGQEIVREGQHHDGQQVADEQDTEQQLAKTTMAVTTTTTSATTTTTSTTTTTTETPLTTTTMQPVEISLLDDSTTTTTTTPAP--------------------------------------------------------PVYFESSTVASTTIRSSTTMLPETTTASTQSPSEMPPTFMAPYPNELDHMQTN-------------------------------------------AQDNGTDVNVIIAITVSVIGVVALILLVAFLYLMRK---RQKQTSYGQRCRPVSLDAYSLDNVSVLGSVRRKGRDMRASKRTYGN-----------------------------------------------------------------------------------AAFDDPSLRHNLLTASELARFVERRSDVFEEFRDVPQIIARAD------EVPPGCEDKNRYANVIPLPE-----------TRVVLQRQGDDDK-------------------------------------------------------------------------------TEYINANYVRGPRDAPNYYIACQAPLESTTSDFWRMIWEQQ----SRVIIQATDLSENGIERCAEYLPPSAT------------LDNHSSYGDYQVTLKHREVKDRYAISTLVLKRVD--------------------GEESRELTHYWYKWPEA-GVPAEEAPIIAMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAIRSLET----------------PKRSVDIPQLVYYVRRGRASAVQTKEQYEFIYKVASMYAAKITNLSNDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ", "identical_positions": 0, "similar_positions": 1, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000002393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXF4-1", "uniprot_id": "TBC15_MOUSE", "id": "Q9CXF4-1", "name": "TBC1 domain family member 15", "aln": "MAAAGVVSGKIIYEQEGVYIHS--SCGKANDQDSLISGILRVLEKDAEVIVDWRPLDDAL--DSSSILCAGKDSSSVVEWTQ-----APKERAHRGSDQQSSYEAEWDMVTTVSFKKKPHTNGDAPG----------------------------HRNGKSKWSFLFSLADLKSVKQSKEGMGWSYLVFCLKDDVMLPALHFHQGDSKLLIESLEKYVVLC---ESPQDSRTLLVNCQN-KSLSQSFEN--LLDEPAYGLIQ------------------------KIKKDPYTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQEEPGFEVITRIDLGERPV---VQRREPVSLEEWNKSLDP-EGRLVA-VESMKQKIFRGGLS-HSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKS--VSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYE------------------------------------GQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMAQCKELPQAVCEILGLQDSEITTPDSDTDEN---VGSPCPVSAFPSSTLPILAASEAKDDSPTQTLASPNACRLTPA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A4L6-1", "uniprot_id": "A0A8I6A4L6_RAT", "id": "A0A8I6A4L6-1", "name": "TBC1 domain family member 15", "aln": "MAAAGVVSGKIIYEQEGVYIHS--SSGKANDQDSLISGILRVLEKDAEVIVDWRPLDDAL--DSSSILYAGKDSSSVVEWTQ-----APKERAHRGSEHQSSYEAEWDMVTTVSFKKKPHTNGDAPS----------------------------HRNGKSKWSFLFSLADLKSIKQSKEGMGWSYLVFCLKDDVVLPALHFHQGDSKLLIESLGKYVVLC---ESSQDSRTLLVNCQN-KSLSQSFEN--LLDEPAYGLIQ------------------------KIKKDPYTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQEEPGFEVITRIDLGERPV---VQRREPVSLEEWTKSLDS-EGRLLN-VESMKQMIFRGGLS-HSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKS--VSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYE------------------------------------GQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMAQCKELPQAVCEILGLQDSEVTTPDSDTDEN---VGTPCPVSAFPSSTLPVVAASEAKEDSPAQTLASPNACRLTPA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TC07-1", "uniprot_id": "TBC15_HUMAN", "id": "Q8TC07-1", "name": "TBC1 domain family member 15", "aln": "MAAAGVVSGKIIYEQEGVYIHS--SCGKTNDQDGLISGILRVLEKDAEVIVDWRPLDDAL--DSSSILYARKDSSSVVEWTQ-----APKERGHRGSEHLNSYEAEWDMVNTVSFKRKPHTNGDAPS----------------------------HRNGKSKWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVVLPALHFHQGDSKLLIESLEKYVVLC---ESPQDKRTLLVNCQN-KSLSQSFEN--LLDEPAYGLIQAGLLDRRKL-------LWAIHHWKKIKKDPYTATMIGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQEEPGFEVITRIDLGERPV---VQRREPVSLEEWTKNIDS-EGRILN-VDNMKQMIFRGGLS-HALRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKS--ISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYE------------------------------------GQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEILGLQGSEVTTPDSDVGEDENVVMTPCPTSAFQSNALPTLSASGARNDSPTQIPVSSDVCRLTPA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5M9-1", "uniprot_id": "A0A8M2B5M9_DANRE", "id": "A0A8M2B5M9-1", "name": "TBC1 domain family member 15", "aln": "MAAT--TPPKVVFEHEGVFIHS--SPDESEDQD-LISGFLRIVEKEGETLVEYKPLEDA---DPSNMLCACKDSSSVVEWTQ-----SSEENPHRPVDHQLSYETEWDMINAVSFRRKVHANGDGGSN---------------------------HVNEQNKRAFSFNVCDLRSVTVKCEG--WSYLTFRLKDGTALPAIHFHQGGSKAFLDSLRKSVQIN---ESPDDESVLIVSTYS-KAFSQSFEN--LLDDTNYGFVQ-----------------------QKFKKDPYTTTLGGFSKVTNYLFDAFRAPELECQQRPAEEVADVLGELIPGLEINQQEEPGFEVITRLDLGPRPE---MQRTGPVTMEEWAKYQDL-EGRMTN-LPHLKDAIFKGGLC-HAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEYFRMKLQWKS--VSEEQERRNSRLRDYRSLIEKDVNRTDRNNKFYE------------------------------------GLDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPILFVMENEVDAFWCFVSFMDEMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWNYLEAQDSGYLYFCFRWLLIRFKRELHFQDVLRLWEVMWTRLPCQNFHLLVCCAILDSEKQKIMDRKYGFNEILKHINELSMKLDIEEILSKSESICMQIKSCKDLPHSVSEILGLNTVSEPSAALETSEYG---ILESPQTSPRSSHRQDHVVSNGHSHLKETTQNGCKVAFIS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BYH7-1", "uniprot_id": "TBC17_MOUSE", "id": "Q8BYH7-1", "name": "TBC1 domain family member 17", "aln": "MEGS---SYRVVFEKGGVYLHT--SARKHQDPDSLIAGVIRVVEKDSDVFLHWAPVEEAG--DPTQILF-KKDPSRGEPSTS-----EEEPTFDPG------YEPDWAVISTVRPQPHLAEPRKGAE----------------------------PSSSRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLA---SSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVS------------------------RFLQDPYSTTFSSFSRVTNFFRGALQPH--------PEGASSPNLPPLP----DDEPEPGFEVISCVELGQRPT---VERAPPVTEEEWNRYVGP-EGRLQN-VPELKNRIFSGGLS-PGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKS--VSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYE------------------------------------GPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSP----MPLSPTRAPLPPPLPEEVIPQPDSSLEILPEDED-GA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA65-1", "uniprot_id": "TBC17_HUMAN", "id": "Q9HA65-1", "name": "TBC1 domain family member 17", "aln": "MEGA---GYRVVFEKGGVYLHT--SAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAG--DSTQILFSKKDSSGGDSCAS-----EEEPTFDPG------YEPDWAVISTVRPQLCHSEPTRGAE----------------------------PSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLA---SSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVS------------------------RFLQDPYSTTFSSFSRVTNFFRGALQPQ--------PEGAAS-DLPPPP----DDEPEPGFEVISCVELGPRPT---VERGPPVTEEEWARHVGP-EGRLQQ-VPELKNRIFSGGLS-PSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKS--VSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYE------------------------------------GPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASP----LPLSPTRAPPTPPPSTDTAPQPDSSLEILPEEEDEGADS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPL5-1", "uniprot_id": "Q9VPL5_DROME", "id": "Q9VPL5-1", "name": "TBC1 domain family member 15", "aln": "-MDESVRYDRCHQVQLGVFNESQLSSVEEDVQNLPQQGTGNILFTHDGVLLKKASAEHIADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQPNDSIMIADDSQDQGDWALVDRISGRTRTTSECRAFNTRPI---------------------EPSGGATTRSRVMRAQLEDLSSVEVRHRG--QTIRFMRKGANGVHSEFFFQHGNADLFVRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQR---VERGHPLTETQWLEFQTP-DGRISD-SARIKELIFRGGVV-QSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLA--MTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFA------------------------------------GEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSIIGEPLLPAAAGEEIDGGMVD---EEPTYSDDGFDELVKELTPEEKVRQQALLEEACERSLFLQFH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48365-1", "uniprot_id": "GYP7_YEAST", "id": "P48365-1", "name": "GTPase-activating protein GYP7", "aln": "-------MSKILFCKSKVFLHP--TSDARDNIAGFLLLTLEANKLSHQAILQYIPESGLSTLEISKLLKHEAKVGTCPTSTPFVIENSINFSNLVNTSLGQAFEISLSQIYCIQFRPPSPNGWYVGSLVIYPLTEQFTGFQPPVLFFHDQLCPSTTDKLKRLRKSMNPFDDSDELYWGGVDLRNKINELMELKKSNLEPEFWLVNPSLNDLRNFVSKDLLESYNNSKKDTTELATAGVKLNEKFQEWKWNVMSKIADVTTKSTNFIDSWLTN--------NSPIQKSQIDNEYLQKLLNNEKVKQIEQDYDSARVYLANWSLGVKQEAERYQKQNKLFDSYRNNIFNDLNLTDELSDTEINNALQRQFPLTEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRGKVWGFLLEIYPWDSSQDERVQIDQTLAAEYDQLKLTWSKDFLQFDDEDEEEYWNDQLFRISKDVRRCDRNLEIFQYNTIDGLPPPPQQLPANENNSTSPESANDESDDADDGVRNPHLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFLRDQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIWENFWTFYYSSQFQLFFMLAILQKNSQAILQHLNQFDQILKFFNELNGKLDWNDLMVRAELLFKKFEKMMHVMERDLQNVSSSSSSSSTG----------------VLPCQSERLTLLLSKKPIIRHEGQRSKNSVK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: .. : : . .::. . . : : * . : : . : : : . : .: . : .: . : : : : * .. . . . : : . .. : . :.. . . : :* ::* *:: :* :**: :*: ** **: .:* :.* *** *..: *: : : ** .:* * : :* . . *.:** * **. ::: * ** * *:.**:** :*. :*******:***:*: : :* .:**** :*: : ** . :: *: : *:.. : ..: **. : **** **: :***: *::::** :** :::*:. ***: : :: :***..***. ::. :. : :* : :: : . . :. . ", "identical_positions": 90, "similar_positions": 154, "identity": "11.45%" }, { "cls_id": "homologset.agr.SGD:S000002395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHP8-1", "uniprot_id": "PGP_MOUSE", "id": "Q8CHP8-1", "name": "Phosphoglycolate phosphatase", "aln": "-----------MAEAEAGGDEARCVRLSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRARGKRLGFITNNSSKTRTAYAEKLRRLGFGGPVGPEAGLEVFGTAYCSALYLRQRLAGVPDPK--AYVLGSPALAAELEAVGVTSVGVGPDVLHG--DGPSDWLA-VPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQ-QPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPER-TVMVGDRLDTDILLGSTCSLK-TILTLTGVSSLEDVKSNQESDCMFKKKMVPDFYVDSIADLLPALQG-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDK7-1", "uniprot_id": "PGP_RAT", "id": "D3ZDK7-1", "name": "Phosphoglycolate phosphatase", "aln": "-----------MAEAEAGGDEVRCVRLSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRARGKRLGFITNNSSKTRTAYAEKLRRLGFGGPMGPEAGLEVFGTAYCSALYLRQRLAGVPDPK--AYVLGSPALAAELEAVGVTSVGVGPDVLHG--DGPSDWLA-VPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQ-QPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPER-TVMVGDRLDTDILLGSTCSLK-TILTLTGVSSLEDVKSNQESDCMFKKKMVPDFYVDSIADLLPALQG-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NDG6-1", "uniprot_id": "PGP_HUMAN", "id": "A6NDG6-1", "name": "Phosphoglycolate phosphatase", "aln": "-----------MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPK--AYVLGSPALAAELEAVGVASVGVGPEPLQG--EGPGDWLH-APLEPDVRAVVVGFDPHFSYMKLTKALRYLQ-QPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPER-TVMVGDRLDTDILLGATCGLK-TILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQG-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGU0-1", "uniprot_id": "F1QGU0_DANRE", "id": "F1QGU0-1", "name": "Glycerol-3-phosphate phosphatase", "aln": "-----------MAAS-------KCVRLNGALSRQLLDSVDCVLFDCDGVIWRGDQAIPGAPEVINSLKKHGKQVFFVTNNSTKTRQMYADKLGKLGFD-----AAADEVFGTAYCSAQYLKN--VCKLDGK--VYLIGSKAMKQELEEVGIQPVGVGPDLISG---VQIDWAN-VPLDQEVQAVLVGFDEHFSYMKLNRALQYLC-DPDCQFVGTNTDTRLPLEGGKAVPGTGCLLRAVETAAQRQAQVVGKPSNFMFECVASQFNLKPQR-CLMVGDRLDTDIMLGSNCGLK-TLLTLTGVSTVAEAEANQKSECPQKQRMVPDYYIESIADILPALQA-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P60487-1", "uniprot_id": "PLPP_MOUSE", "id": "P60487-1", "name": "Chronophin", "aln": "--------------------MARCERLRGAALRDVLGQAQGVLFDCDGVLWNGERIVPGAPELLQRLARAGKNTLFVSNNSRRARPELALRFARLGFAG----LRAEQLFSSALCAARLLRQRLSGPPDASGAVFVLGGEGLRAELRAAGLRLAGDP------------------GEDPRVRAVLVGYDEQFSFSRLTEACAHLR-DPDCLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITEDFSVDPAR-TLMVGDRLETDILFGHRCGMT-TVLTLTGVSSLEEAQAYLTAG---QRDLVPHYYVESIADLMEGLED-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VD52-1", "uniprot_id": "PLPP_RAT", "id": "Q8VD52-1", "name": "Chronophin", "aln": "--------------------MARCERLRGAALRDVLGQAQGVLFDCDGVLWNGERIVPGAPELLQRLAQAGKATLFVSNNSRRARPELALRFARLGFTG----LRAEELFSSAVCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDP------------------GDDPRVRAVLVGYDEHFSFAKLTEACAHLR-DPDCLLVATDRDPWHPLTDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITEDFSVDPAR-MLMVGDRLETDILFGHRCGMT-TVLTLTGVSSLEEAQAYLAAG---QHDLVPHYYVESIADLMEGLGGLSPPPQFPDPVDGGYRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GD0-1", "uniprot_id": "PLPP_HUMAN", "id": "Q96GD0-1", "name": "Chronophin", "aln": "--------------------MARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGG----LRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPS-------------AG-DGAAPRVRAVLVGYDEHFSFAKLREACAHLR-DPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPAR-TLMVGDRLETDILFGHRCGMT-TVLTLTGVSRLEEAQAYLAAG---QHDLVPHYYVESIADLTEGLED-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W272-1", "uniprot_id": "Q9W272_DROME", "id": "Q9W272-1", "name": "", "aln": "---------------MLRRSLSHLDKLPKAKVAEWLAGIDTIICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFN-----VKEQDIFSSSGAIASYLSDR-----KFKKKILVLGGDGIRKDLKEAGFCSVVNDLQPND---QKKIDFVRSLVLDPDVGAVLVARDDNMIANELLVACNYLQ-NPKVLFLTTCIDGFQPFGK-KRIPDAGSLASAIEIIVQRKPIVLGKPNQRILGKLMKSGEIKPEK-TLVIGNSLKSDILFASICGFQ-SLLVGCDNGAIEKAEKIKKEGDEKKMKLVPDAFLSGLASFGEYLCI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW4-1", "uniprot_id": "Q9VZW4_DROME", "id": "Q9VZW4-1", "name": "", "aln": "--------MNLALNKTFQKRGCQILGLNKYGIQQWLKTIDTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFL-----VAKNEILSSVQTLAKFMKEK-----KFKKKCYVVGGQGIVDELKLVGIESLPLDHSSLQG--FSMPDHIHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLR-DSEVMFVATSRDAALPAAPGRMVPSAGVMVAAIQAASQRMPFTCGKPNPYMCIDLMQKGVIQPDR-TLIIGDTMCTDILLGYKCGFQ-TLLVGTGVNSYQDAIEAQGSKAPLLYQQVPDLYMPKLSNLLPFLSSRNR--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVL5-1", "uniprot_id": "Q9VVL5_DROME", "id": "Q9VVL5-1", "name": "4-nitrophenylphosphatase", "aln": "MSCNFARFSRQAAINMYKQSCTNLLELSSAKVTEWLAGFDSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVELGFH-----IKENGIISTAHATAAYLKRR-----NFSKRVFVIGSEGITKELDAVGIQHTEVGPEPMKG--SLAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLN-DPECLFVATNTDERFPMPN-MIVPGSGSFVRAIQTCAERDPVVIGKPNPAICESLVTEKKIDPSR-TLMIGDRANTDILLGFNCGFQ-TLLVGSGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLLPSIVNSLTDLK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19881-1", "uniprot_id": "PGP_YEAST", "id": "P19881-1", "name": "Phosphoglycolate phosphatase", "aln": "---------------MTAQQGVPIKITNKEIAQEFLDKYDTFLFDCDGVLWLGSQALPYTLEILNLLKQLGKQLIFVTNNSTKSRLAYTKKFASFGID-----VKEEQIFTSGYASAVYIRDFLKLQ-PGKDKVWVFGESGIGEELKLMGYESLGGADSRLDTPFDAAKSPFLVNGLDKDVSCVIAGLDTKVNYHRLAVTLQYLQ-KDSVHFVGTNVDSTFPQKG-YTFPGAGSMIESLAFSSNRRPSYCGKPNQNMLNSIISAFNLDRSK-CCMVGDRLNTDMKFGVEGGLGGTLLVLSGIETEERALKISHDYP------RPKFYIDKLGDIYTLTNNEL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W4W5-1", "uniprot_id": "Q9W4W5_DROME", "id": "Q9W4W5-1", "name": "4-nitrophenylphosphatase", "aln": "-----------------MSPPRHILKLSLEEQRQFIDSFDLVISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKN----VQEDDIVHPVKTIVRYLKKH-----KPGERVYSLMSLEANETLRKHNIEFESLQVKEHLT----AASLVDHLAIEKPVGAVLFDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFFDFLEHVKRYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGDTLVQDVQFGKACGFQ-SLLVLSGCLTKEDMLN-------APVEAQPDYYADSLADFTQLLENIQK--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: . :**:* : : .. : ** : :*:. : :* :. . . : . * . : .*: . .. .: : :* . :: * * .. : : * . ***. : . : : .:*: *: :. .: ::*. . *. : :..: ", "identical_positions": 20, "similar_positions": 66, "identity": "5.6%" }, { "cls_id": "homologset.agr.SGD:S000002397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R111-1", "uniprot_id": "GUAD_MOUSE", "id": "Q9R111-1", "name": "Guanine deaminase", "aln": "--------MCAARTPPLALVFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEESSQQ---EKLAKEWCFKP--CEIRELS------HHEFFMPGLVDTHIHAPQYAFAGSNVDLPLLEWLNKYTFPTEQRFRSTDVAEEVYTRVVRRTLKNGTTTACYFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNDTVPEYKETTEESVKETERFVSEMLQ-KNYPRVKPIVTPRFTLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVKSLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNIFSERGASIAHCPNSNLSLSSGLLNVLEVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINK--------------VNEKNLTLKEVFRLATLGGSQALGLDSEIGNFEVGKEFDALLINPRASDSPIDLFYGDFVGD---------------------ISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTT6-1", "uniprot_id": "GUAD_RAT", "id": "Q9WTT6-1", "name": "Guanine deaminase", "aln": "--------MCAARRRELALIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEESSQQ---EKLAKEWCFKP--CEIRELS------HHEFFMPGLVDTHIHAPQYAFAGSNVDLPLLDWLNKYTFPTEKRFQSTDVAEEVYTRVVRRTLKNGTTTACYFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNNTVPEYKETTEESVKETERFVSEMLQ-KNYSRVKPIVTPRFSLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVKSLYPGYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNVFSERGASIAHCPNSNLSLSSGLLNVLDVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINK--------------VNEKSLTLKEVFRLATLGGSQALGLDREIGNFEVGKDFDALLINPRASDSPIDLFCGDFVGD---------------------ISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T3-1", "uniprot_id": "GUAD_HUMAN", "id": "Q9Y2T3-1", "name": "Guanine deaminase", "aln": "--------MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQ---EKLAKEWCFKP--CEIRELS------HHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQ-KNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINK--------------VNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGD---------------------ISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMY9-1", "uniprot_id": "GUAD_DROME", "id": "Q9VMY9-1", "name": "Guanine deaminase", "aln": "----------------MATVFLGTVVHTKSFSEFESFEGGFLAVDDAGKIIGVGQDYHA---WASSNPAHAKG--LTEVHLS------DYQFLMPGFVDCHIHAPQFAQLGLGLDMPLLDWLNTYTFPLEAKFSNHQYAQQVYQGVVEATLRCGTTLASYFATNHLESTLTLAREAVRQGQRALIGKVCSNCNSPE-FYVETAEESVSATLAFVEGVRK-LGSPMVMPTITPRFALSCSKELLKSLGDIAKRFDLHIQSHISENLEEIEMVKGIFK--TSYAGAYDEAGLLTNKTVLAHGVHLEDDEVALLKVRGCSVAHCPTSNTMLSSGLCDVQRLVSGGVSVGLGTDVSGGNSVSIQDVLLRALDVSKHLDFFKKQNIRGTGVSKTQDFNYHQLKYKQALYLATLGGAKALSLDHLTGNFALGKDFDALLVDVSVVDKPLRRLS----------------------------VDELVEKFIYTGSDRNIVEVFVAGKRIKQGYQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07729-1", "uniprot_id": "GUAD_YEAST", "id": "Q07729-1", "name": "Probable guanine deaminase", "aln": "MTKSDLLFDKFNDKHGKFLVFFGTFVDTPKLGELRIREKTSVGVLN-GIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDIIGKDKTRNNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPE-YYIEDTKTSFESTVKVVKYIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRE--------------TDHAKLSVSECLFLATMGGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKEKDQMQEQEQEQGQDPYKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **.*.: :. . :.* : * * : . : . .: . .* :**:** * *..*:. * : .**:** .**** * : . : *.:** *: ** *** ..*: * . .*: ** : ***.::**** : *.. * * :: *.. * .*. : : . * * :****: **:. *: .*..:.* ::::*:*:*** :*:: *:.:: .*:..**: .***:***:** :* * :: * ..::*** ** *:** * ::. :.:******:.* * *: . :*. **. * : : : .*. .: : ***:**::.* :* *.* :**:*** ::: . .. : : : :: *::: *.*** :*:*.*::: ", "identical_positions": 129, "similar_positions": 145, "identity": "25.34%" }, { "cls_id": "homologset.agr.SGD:S000002399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50462-1", "uniprot_id": "CSRP3_MOUSE", "id": "P50462-1", "name": "Cysteine and glycine-rich protein 3", "aln": "------------------MPNWGGGAKCGACEKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRRYG-----------------PKG---------------------------------IGFGQGAG--------------------------------------------------------------------------CLSTDTGEHLGLQFQQSPKPARAATTSNPSKFSAKFG----------------------------------------------------------------------------------------ESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTD-----KDGELYCKVCYAKN-FGPTGIGFGGLTQQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50463-1", "uniprot_id": "CSRP3_RAT", "id": "P50463-1", "name": "Cysteine and glycine-rich protein 3", "aln": "------------------MPNWGGGAKCGACDKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRKYG-----------------PKG---------------------------------IGFGQGAG--------------------------------------------------------------------------CLSTDTGEHLGLQFQQSPKPARAATTSNPSKFSAKFG----------------------------------------------------------------------------------------ESEKCPRCGKSVYAAEKVMGGGKPWHKTCFPCAICGKSLESTNVTD-----KDGELYCKVCYAKN-FGPTGIGFGGLTHQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50461-1", "uniprot_id": "CSRP3_HUMAN", "id": "P50461-1", "name": "Cysteine and glycine-rich protein 3", "aln": "------------------MPNWGGGAKCGACEKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRRYG-----------------PKG---------------------------------IGYGQGAG--------------------------------------------------------------------------CLSTDTGEHLGLQFQQSPKPARSVTTSNPSKFTAKFG----------------------------------------------------------------------------------------ESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTD-----KDGELYCKVCYAKN-FGPTGIGFGGLTQQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJC0-1", "uniprot_id": "F1QJC0_DANRE", "id": "F1QJC0-1", "name": "Cysteine and glycine-rich protein 1", "aln": "------------------MPNWGGGAKCAACEKTVY-----HAEEIQCNSRSFHKTCFICMVCRKGLDS----------------------------------------------------------------TTVAAHESEIYCKTCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------ALSSDPVNNEELQPQEPKAPRPAPANSNSSKFAQKFG----------------------------------------------------------------------------------------STDRCPRCSKAVYAAEKIMGAGKPWHKTCFRCLLCGKSLESTTVTD-----KDGELYCKVCYAKN-FGPKGRGLG-NPGMVEESV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97315-1", "uniprot_id": "CSRP1_MOUSE", "id": "P97315-1", "name": "Cysteine and glycine-rich protein 1", "aln": "------------------MPNWGGGKKCGVCQKTVY-----FAEEVQCEGNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLSTDKGESLGIK-HEEAPGHRPTTNPNASKFAQKIG----------------------------------------------------------------------------------------GSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLAD-----KDGEIYCKGCYAKN-FGPKGFGFGQGAGALVHSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21291-1", "uniprot_id": "CSRP1_HUMAN", "id": "P21291-1", "name": "Cysteine and glycine-rich protein 1", "aln": "------------------MPNWGGGKKCGVCQKTVY-----FAEEVQCEGNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLSTDKGESLGIK-HEEAPGHRPTTNPNASKFAQKIG----------------------------------------------------------------------------------------GSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLAD-----KDGEIYCKGCYAKN-FGPKGFGFGQGAGALVHSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47875-1", "uniprot_id": "CSRP1_RAT", "id": "P47875-1", "name": "Cysteine and glycine-rich protein 1", "aln": "------------------MPNWGGGKKCGVCQKTVY-----FAEEVQCEGNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLSMDKGESLGIK-HEEAPGHRPTTNPNASKFAQKIG----------------------------------------------------------------------------------------GSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLAD-----KDGEIYCKGCYAKN-FGPKGFGFGQGAGALVHSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97314-1", "uniprot_id": "CSRP2_MOUSE", "id": "P97314-1", "name": "Cysteine and glycine-rich protein 2", "aln": "------------------MPVWGGGNKCGACGRTVY-----HAEEVQCDGRSFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLNMDRGERLGIK-PESAQPHRPTTNPNTSKFAQKYG----------------------------------------------------------------------------------------GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62908-1", "uniprot_id": "CSRP2_RAT", "id": "Q62908-1", "name": "Cysteine and glycine-rich protein 2", "aln": "------------------MPVWGGGNKCGACGRTVY-----HAEEVQCDGRTFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLNMDRGERLGIK-PESAQPHRPTTNPNTSKFAQKYG----------------------------------------------------------------------------------------GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16527-1", "uniprot_id": "CSRP2_HUMAN", "id": "Q16527-1", "name": "Cysteine and glycine-rich protein 2", "aln": "------------------MPVWGGGNKCGACGRTVY-----HAEEVQCDGRSFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYG-----------------PKG---------------------------------YGYGQGAG--------------------------------------------------------------------------TLNMDRGERLGIK-PESVQPHRPTTNPNTSKFAQKYG----------------------------------------------------------------------------------------GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35688-1", "uniprot_id": "LRG1_YEAST", "id": "P35688-1", "name": "Rho-GTPase-activating protein LRG1", "aln": "MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQLLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFLREVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHR-WHIACFTCSSCHKNINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTVMLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQARELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDNVPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLDNYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *. * : * ::. .. :*. ** * *:* *.. .. : .::*** : : :. *** :. .:* *. . : :: : . : .: ***. : . :: *. *.. : : : ** ** * * *.::. .::: :. :: *. * .: . * : ", "identical_positions": 33, "similar_positions": 66, "identity": "3.24%" }, { "cls_id": "homologset.agr.SGD:S000002402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43488-1", "uniprot_id": "ARK72_HUMAN", "id": "O43488-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVAS--------VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLK-----------PDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDK----DGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP--LEPAVVDAFNQAWHLVAHECPNYFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CG45-1", "uniprot_id": "ARK72_RAT", "id": "Q8CG45-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "MLRAVSRAVSRAAVRCAWRSGPSVARPLAMSRSPAPRAVSGAPLRPGTVLGTMEMGRRMDASASAATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKSLK-----------PDSVRSQLETSLKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYEDK----DGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGP--LEPAVVEAFNQAWNVVAHECPNYFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95154-1", "uniprot_id": "ARK73_HUMAN", "id": "O95154-1", "name": "Aldo-keto reductase family 7 member A3", "aln": "-----------------------MSRQLSRARPAT-------------VLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLK-----------PDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDK----NGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP--LEPAVVDAFNQAWHLVTHECPNYFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38918-1", "uniprot_id": "ARK73_RAT", "id": "P38918-1", "name": "Aldo-keto reductase family 7 member A3", "aln": "---------------------------MSQARPAT-------------VLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLK-----------PADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDK----DGKNPESRFFGNPFSQLYMDRYWKEEHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEEGP--LEPAVVDAFDQAWNLVAHECPNYFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07747-1", "uniprot_id": "AAD4_YEAST", "id": "Q07747-1", "name": "Probable aryl-alcohol dehydrogenase AAD4", "aln": "------------------------------------------------------MG-SMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMKSRKLRDQIVIATKFTGDYKKYEVGGGKSANYCGNHKHSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTVSGTSKQTDKEVKISEALAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKIEHLKQNIEALSIKLTPEQIEYLESIIPFDVGFPTNFIGDDPAVTKKASLLTAMSAQISFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *: : ** : * . :*** * : :** :* . * . : : .:: .:. **::** :*::*:* *: :.: *.: : : * *:**.: **:*: :* *: ...:* ::*** :*. .*:.* :::* *:**: : .:: :.** : .: ::: :* .. . :. : .. : : : .*: :* : .. . : . :. .. :: * ..:* **. :. * : . .:* :.: .. * ", "identical_positions": 55, "similar_positions": 109, "identity": "14.32%" }, { "cls_id": "homologset.agr.SGD:S000002404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS------PAIPSLRRT--APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE-------------------EPPVGAEHQGFQLALLRRPGIYKP-LIIGISLMVFQQLSGVNAIMFYANSIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG----------------------------------------------------------------LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT--APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE-------------------EPPVGAEHQGFQLAMLRRPGVHKP-LIIGICLMVFQQLSGVNAIMFYANTIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGL---------------------------------------------------------------LVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS--SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE---------------QIQDNVRRQSSRVSWAEAWEPRVYRP-ILITVLMRFLQQLTGITPILVYLQTIFDSTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVT---------------------------------------------------------------LGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR--TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKE-----------LMQSQADADRQATQNTCLELFKRNNLKP-LSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA-----------------------------------------------------------------------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR--NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKG-----------LMRSQADADRQASRNTMLELLKLNNLKP-LSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT-----------------------------------------------------------------------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRG-EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAE-----------LRETDRETKANKVN-VWAALNRPVTRKA-LAISMGLMFFQQVCGINAVIFYASRIFLEANTG--IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ----------------------------------------------------------------------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND-------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVS-------WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQ-----------AIQNDLDQTGVDAS-VKDLFSNRASRNG-MVISVLLMVFQQFSGINAVIFFMNEIFESSST---LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR-----------------------------------------------------------------------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQN6-1", "uniprot_id": "Q9VQN6_DROME", "id": "Q9VQN6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLISIFKSGIFQWQYR-------------------------------------------------------------------------------------------------------------------------------------------------------------RQLLVSLSATLITFCHGIALGWLS------PMLPKLLSPQETPLSFYIDVNEASWLGAVISIGGISGNFSFSYLMNRFGRKVSIYALAVPHTCIWFLFYFAQS-IEWLYVARVFAGLTGGGMFVVLPIFIGEIADNSIRGRLCSFFTLTMNTGIMVGFVVSSHIA-------YHVIPCAVVGLPVLYVLLATRYPEPPQQLIRWKREEEAEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRLAIQQQNNDTDDNGLSMSDFLTKRSLKA-LATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQ--LDPNTNTIIIGAVQILGTLASIYLVDRYGRKILLIVSCAGSGIGTSAFGLYAFYAEE---------------------------------------------------------------------------------QKVDLSAFSAWLPVTLMAFIIFIANVGVISVTMVVLVEILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWFCAAVSVICLFYVVVCLEETKGRSMYD----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8TD20-1", "uniprot_id": "GTR12_HUMAN", "id": "Q8TD20-1", "name": "Solute carrier family 2, facilitated glucose transporter member 12", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARG-----------------------------------------------------------------------------------------------------------------------------------------------CGMFTFLSSVTAAVSGLLVGYELGIIS------GALLQIKTL------LALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLS-YTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVF--HGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELT---------------VIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECNKLCGRGQSRQLSPET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54854-1", "uniprot_id": "HXT15_YEAST", "id": "P54854-1", "name": "Hexose transporter HXT15", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINADNLN-----------------------SSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPKRGFLG-----------------------------------------------------------------------------------------------------------------------------------------------YLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQADEIN--------AGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLT---DGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYP------------------------------------------------------------------------------HGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYG-YVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . . .. . : : **: : : .:. *. . : .* ** * * : : * .* :: * : . : : : . * . : :: : :* :... . . :: * : * . :. : . : .:. ::: * : :. * .. :. :. : ** * : : ", "identical_positions": 20, "similar_positions": 72, "identity": "1.99%" }, { "cls_id": "homologset.agr.SGD:S000002405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64442-1", "uniprot_id": "DHSO_MOUSE", "id": "Q64442-1", "name": "Sorbitol dehydrogenase", "aln": "MAAPAKGENLSLVVHGPGDIRLENYPIPEL-GPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTVTKVGELVKHLKPGDRVAIEPGVPREVDEYCKIGRYNLTPTIFFCATPPDDGNLCRFYKHNADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPVGMVTLLVAKAMGAAQVVVTDLSASRLTKAKEVGADFTIQVGKE---TPQEIASKVESLLGS-KPEVTIECTGAESSVQTGIYATHSGGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCN-TWPMAISMLASKTLNVKPLVTHRFPLEKAVEAFETAKKGVG--LKVMIKCDPNDQNP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27867-1", "uniprot_id": "DHSO_RAT", "id": "P27867-1", "name": "Sorbitol dehydrogenase", "aln": "MAAPAKGENLSLVVHGPGDIRLENYPIPEL-GPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRYNLTPSIFFCATPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAKEVGADFTIQVAKE---TPHDIAKKVESVLGS-KPEVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAVREVDIKGVFRYCN-TWPMAVSMLASKTLNVKPLVTHRFPLEKAVEAFETAKKGLG--LKVMIKCDPNDQNP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00796-1", "uniprot_id": "DHSO_HUMAN", "id": "Q00796-1", "name": "Sorbitol dehydrogenase", "aln": "MAAAAKPNNLSLVVHGPGDLRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE---SPQEIARKVEGQLGC-KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN-TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLG--LKIMLKCDPSDQNP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96299-1", "uniprot_id": "O96299_DROME", "id": "O96299-1", "name": "Sorbitol dehydrogenase", "aln": "MAT----DNLTAVLHGIEDLRLEQRPIPEI-ADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMVFCATPPYDGNLTRYYKHAADFCFKLPDHVSMEEGALLEPLSVGVHACRRAGVGLGSKVLILGAGPIGLVTLLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRDQ--SAEETVKVVHQTMSE-VPDKSIDCCGAESSARLAIFATRSGGVVVVVGMGAPEVKLPLINALAREIDIRGVFRYCN-DYSAALALVASGKVNVKRLVTHHYDITETAEAFETSRRGTGGAIKVMIHVQPRDANNKVKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O97479-1", "uniprot_id": "O97479_DROME", "id": "O97479-1", "name": "Sorbitol dehydrogenase", "aln": "MAK----DNLTAVLHGIEDMRLEQRPIPEI-ADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPYDGNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPIGLVTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQ--TAEETAVLVQKTMGG-QPDKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVDIRGVFRYCN-DYAAALALVASGKVNVKRLVTHHFDIKETAKAFETSRKGLGGAIKVMIHVQPRDTNNPRKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07786-1", "uniprot_id": "DHSO2_YEAST", "id": "Q07786-1", "name": "Sorbitol dehydrogenase 2", "aln": "MSQ---NSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFG-PE--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* : *:. *: :*: *** . * * :.:.******:** * **.:::. **::***::* * ::* *. :* *********.* . : * * *** . : *.**** **.* ::* * ***: *: **** :******::: : . * :* **:: ****:*::* .*:*:**::::. *: :* **:.** .: : ...: . *. :. .: ::* **: . .: :*: ** :* **:* ..*: .. :*:.: * ***. : *: ::*: .:*** *:**:: : .: :*:: * :* :: * ", "identical_positions": 119, "similar_positions": 114, "identity": "32.25%" }, { "cls_id": "homologset.agr.SGD:S000002406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VQP1-1", "uniprot_id": "Q9VQP1_DROME", "id": "Q9VQP1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---MTFKLRLASVFANPNCLLGRRIRHQFLVTLLLNIATFSHGLGVG--------------------WMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVG--------------------------------------------------------IGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTR---------VDYFTSPPFIIGLPVCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIR--KNDIKAEDEFEEMKYLLIKEQT-EKAKSFDYRDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIG-VLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCFVFLCNIGLVGCLFVVLVELFPAKIRSVSVSTF--VVILSSTVFLTLKIFPICMAVWGT-SVTMWSCSGITFFSFLYFCFFLEETNGKSLLAA-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI79-1", "uniprot_id": "Q9VI79_DROME", "id": "Q9VI79-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------MSLTHGISLG--------------------WFSPTLPTLISDNSPIGHPIDISEVKWIGASFG--------------------------------------------------------IGCLICNMVICVPVSYFGIKKCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSGITVGFVLVYC---------LSYHVLPCVVIFLPILYLCLIIPLPEPPQDLLKRGHEEKAEKSFCFYKNLS--KDPAQQDDNKAEFDKLRNKVLASGIAEKITPADFFNKVSGKAFGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLG-VVQIFGLISAVLLVDRVGRRLLLIPSLAGMGLAELGVGLLKSFASQDFLHNNGWIALTLMGIVSFTASAGIVALTFVIIVELLPFKIRAPGISIS--MCGLSLSVFIALITYPVLINDYGV-HVTMFVSASFCLLGLVVLGIFLPETRGKSITQ------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CD99-1", "uniprot_id": "MPH2_YEAST", "id": "P0CD99-1", "name": "Alpha-glucosides permease MPH2", "aln": "MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGLDIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKR-LTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSSTHGSKMGSG----SLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSARKFKSTKVDPFVVKTPLKTSLITTPREISKLPLQRNSNVSHHL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..*:.: :... :*:* . *: : .: : * :: : :. .* : : : : ::** .. : : : : *:. * : :*:. :* * : : * . : :.* . **: : **.* *:::*: : *.:*: . :. : ::. * ::. * : : : * :.* : . : * : .: : .: :: : * . : . ** * . : .* : : . . :: . * . *:. * :: *: . ::*: : : : .* : : :. : : . : : :: . * ** **:: ", "identical_positions": 45, "similar_positions": 129, "identity": "7.33%" }, { "cls_id": "homologset.agr.SGD:S000002408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLT2-1", "uniprot_id": "TREA_MOUSE", "id": "Q9JLT2-1", "name": "Trehalase", "aln": "-----------------------------------------------------------------MTWELHLLLLLG--LGLRSQEALPPPCESQIYCHGELLHQVQ--MAQLYQDDKQFVDMSLA--------------------------------TSPDEVLQKFSELATVH-NHSIPKEQLQEFVQSHFQ-----------------------PVGQELQSWTPEDWKDSPQFLQKISDANLRVWAEELHKIWKKLGKKMKAEVLSYPERSSLIYSKH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRIYYLQRSQPPLLTLMMDRYVAHTKDVAFLQENIGTLASELDFWTVNRTVSVVSG---GQSYVLNRYYVPYGGPRPESYRKDAE-------LANSVPE-GDRETLWAELKAGAESGWDFSSRWLVG--GPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDT----------EATKYRNLRAQRLAAMEAVLWDEQKGAWFDYDLEKGKKNLEFYPSNLSPLWAGCFSDPS---VADKALKYLEDSK---ILTYQYGIPTSLR-NTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKS-AMFEKYDIS----------NGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSG-----------------------------------------------------------------------------------TQLASLGPHCLVAALLLSLLLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7Q9-1", "uniprot_id": "G3V7Q9_RAT", "id": "G3V7Q9-1", "name": "Trehalase", "aln": "-----------------------------------------------------------------MTWELHLLLLLG--LGLSSQEALPPPCESQIYCHGELLHQVQ--MAQLYQDDKQFVDMSLA--------------------------------TSPDEVLQKFSELAVAH-NHSIPREELQNFVQSYFQ-----------------------PVGQELQPWTPEDWKDSPQFLQKISDSRLRVWAEELHKIWKKLGKKMKAEVLSHPERSSLIYSEH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRVYYLQRSHPPLLTLMMERYVAHTNDVAFLRENIGTLALELEFWTVNRTVSVGSG---GQSYILNRYYVPYGGPRPESYSKDEE-------LAKTVPE-GDRETLWAELKAGAESGWDFSSRWLVG--GPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDT----------EAKRYRNLRAQRLAAMEAILWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWAGCFSDPS---VADRALKYLEDNK---ILTYQYGIPTSLR-NTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKS-AMYEKYDIS----------NGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSG-----------------------------------------------------------------------------------TQLASLGPHCLVTALLLSLLLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43280-1", "uniprot_id": "TREA_HUMAN", "id": "O43280-1", "name": "Trehalase", "aln": "--------------------------------------------------------------MPGRTWELCLLLLLG--LGLGSQEALPPPCESEIYCHGELLNQVQ--MAKLYQDDKQFVDMPLS--------------------------------IAPEQVLQTFTELSRDH-NHSIPREQLQAFVHEHFQ-----------------------AKGQELQPWTPADWKDSPQFLQKISDAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTNDTAFLQENIETLALELDFWTKNRTVSVSLE---GKNYLLNRYYVPYGGPRPESYSKDVE-------LADTLPE-GDREALWAELKAGAESGWDFSSRWLIG--GPNPNSLSGIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDS----------QATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCFSDPG---VADKALKYLEDNR---ILTYQYGIPTSLQ-KTGQQWDFPNAWAPLQDLVIRGLAKAPLRRAQEVAFQLAQNWIRTNFDVYSQKS-AMYEKYDVS----------NGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLTSG-----------------------------------------------------------------------------------AKLAFLEPHCLAATLLPSLLLSLLPW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PUG5-1", "uniprot_id": "A0A8M1PUG5_DANRE", "id": "A0A8M1PUG5-1", "name": "Trehalase", "aln": "---------------------------------------------------------------------MHCLIVISSTLLFSSGDALLAPCDSQIYCTGEVLRQVQ--MAKLFDDDKYFVDMTLT--------------------------------TAPEVVLEAFTNLSSVFPDKAVPSLELKKFLQTYFK-----------------------EPGNEFERWTPTDWHSKPNFLSKVSDSKYRSWAEELHSLWKSLGRKIRDDVRDHPELYSQIYTPH-------------PVVVPGGRFRELYYWDSYWVINGLLLSEMTETARGMILNFVYLVERYGIVPNGGRVYYERRSQPPFLPLMVERFYEATGDKDFLRQVLPALEREYSFWMQNRSVDVVTS---ELTHILNRYNVPVDHPRPESYSDDVE-------LAEGLST-EAQKQLWMDLTSGAESGWDFSSRWFIDDTGRNNGSLRDTQTSSILPADLNAIMCRNERLLASFHRSLGNEE----------KALKYEKALSARIKAVESLLWDAEKGAWFDYNLVNKTRHLSFYPSNLAPLWAQCYSKSE---MSDQAVQYLRDSG---GLDYPNGIPTSLS-DSGQQWDMPNTWPPLQHIIIEGLSGLHSAHAQELAFSLAQRWIQTNWRAFIKYE-AMFEKYDVS----------GDGKPGGGGEYEVQLGFGWTNGVALQLLDQYGDRLSSGGR---------------------------------------------------------------------------------VPVCSSALIGLVYAVLKSLF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2M2-1", "uniprot_id": "TREA_DROME", "id": "Q9W2M2-1", "name": "Trehalase", "aln": "-----------------------------------------MFKLPTISLLLVSWSCLVALSQAKTYSLPDLTTDYNNAIPVDEEEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKTFVDMKLN--------------------------------NSPDKTLEDFNAMMEAK-NQTPSSEDLKQFVDKYFS-----------------------APGTELEKWTPTDWKENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSKNPEYYSIIPVPN-------------PVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFVNNHNVTVKN-------HSLCVYRDSSSGPRPESYREDVE-------TGEEFPTDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIAEFHSKAGNTK----------KVTEYETKAEKLLLGIQEVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISASVMAYIERNK---LDSFPGGVPNTLS-YTGEQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAFSKDR-HMYEKYNAD----------EFGVGGGGGEYEVQTGFGWSNGVIIEWLSKHGRDISIG----------------SG------------------------------------------------------------------------CGCLAGEKRQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAE9-1", "uniprot_id": "A1ZAE9_DROME", "id": "A1ZAE9-1", "name": "Trehalase", "aln": "-----------------------------------------------------------------------MANKCRCGAEVLGGENRG------VFCEGPLLDAVQ--RSKMFPDCKHFVDMSCI--------------------------------FTPAQTLADFDMFTNCR-RNDGSLRFLQMFVEKHFN-----------------------DPGSELEHWTPPDWKAQPSFLARISDPEIKQFGSDVNGLWKELGRRIKDEVKENPDQYSIIYVPN-------------PFIVPSSNCREYRYWESFWIIRGLLQCGMHQTARGMIDNYLELVQQYGFVPGCGRIYCSGRSNPPLLIMMVKAYVEVTKDEQYAIEALPLLETEYDTFISKHSVQVKG-------RTMYQYRDSSAGPRPEAYREDLE-------CVASIKSPVVREVMYTELKSAAESGTNFSSRWYVTVDGSNKGSFRDIKTSAIVPVELNCIVFRSGKILAEFNRKAGNTK----------KADEYQDRACVLVKAIRDNLWNAQAGIWLDYDLVNNKPRNYFCCTNFAPLWARAFPLVDTEKVSKGVMQYIKTND---LDAQYGGVPYTMNKESGQNWDHPNVFPPMMFLIIEGLENLGTPPAKAMSKRWAHRWVKSNYAAYKYES-FMFEKYYCE----------DFGTSGGSSPENTPLGYGWTNGVIIEFLCKYGKEISLADTSDEGSKSKSRGSKPSGKYQYIITSEANMDDQPSKKRCVCGAPSMVGTMSHKSTATTATSDFAQQTQPPCSCGIAQKQRSQTQPGEDGKCSCGAGAKEKSQQQLQPKDAPSCGICGSQKQQPSQAQMQRSQQKVDDDQCTCSRKEALQQSQSQQQRTLGIQHDPDCPCAGPQQKGAGLIVVQGQVPDTDPDCECSMDERQKQQMEQQQKQQDCMRQQQQQQQEHQKQQQQLQSEQQQDCTTKPQTQDCSQHLKKSNGGCGCQDDEDEDRHDALTGHYFPVADKDPDDVYQQESKSTQRESGCDGCGRDDCPDPPQEDCGCSPVAKPQQTPIAECAPQPKAPQPAPADDCSCAVGKSQSKAASVVPPPTFICPHCGGVTSEAFLSTHTIGTNRTMGPQDDCGAAGQPLRGLASKGIQSGHSKVVAGGAGAECAPCKAHVTADFPAGHGPKPLFNKQFPLADPASNFDACPPKRGSDPTNNKKKKCCNCDEKEDGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32356-1", "uniprot_id": "TREA_YEAST", "id": "P32356-1", "name": "Cytosolic neutral trehalase", "aln": "MSQVNTSQGPVAQGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRKQKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHP-SLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGG-RSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISIS-RPIRQWDYPFGWAPHQILAWEGLRSYG---YLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALG---------------------------------------------------------------------------------ACIPPISFFSSLRPQERNLYGL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . * : : : : : . : : . *. ::. * . : . :.* * . .* *: ::. : *.: . .* . * : : * **... * *:*: : *** . ...:**: ::. :: :* : . .* * **:**:* * . : : * . : .. : * **: .. : . :: .: . * : * : : : . :**. : ::.* : :. : :*: : * ::**: :.: .**. : .: :. * :: . .:** * :.* : .** :: * .*: .: : *** * *.. . *:** *. : * . . ", "identical_positions": 64, "similar_positions": 134, "identity": "5.21%" }, { "cls_id": "homologset.agr.SGD:S000002409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34022-1", "uniprot_id": "RANG_MOUSE", "id": "P34022-1", "name": "Ran-specific GTPase-activating protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKDS----------------HEDHDTSTENADESNHDP-----------------QFEPIVSLP-EQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPN-AGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKK-GPGKNDNAEKVAEKLEALSVREAREEAEEKSEEKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2G9-1", "uniprot_id": "D4A2G9_RAT", "id": "D4A2G9-1", "name": "Ran-specific GTPase-activating protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMPTVDQIHQPA------ASLLTLSTQDS----------------HEDHDTSTENAEESNHDP-----------------QFEPIVSLP-EQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPN-AGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKK-GPGKNDNAEKVAEKLEALSVREARDEAEEKSEEKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43487-1", "uniprot_id": "RANG_HUMAN", "id": "P43487-1", "name": "Ran-specific GTPase-activating protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKDT----------------HEDHDTSTENTDESNHDP-----------------QFEPIVSLP-EQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGAIRLLMRRDKTLKICANHYITPMMELKPN-AGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSV---KEETKEDAEEKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41920-1", "uniprot_id": "YRB1_YEAST", "id": "P41920-1", "name": "Ran-specific GTPase-activating protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSEDKKPVVDKKEEAAPKPPSSAVFSMFGGKKAE----------KPETKKDEEDTKEETKKEGDDAPE------------SPDIHFEPVVHLE-KVDVKTMEEDEEVLYKVRAKLFRFDA--DAKEWKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPN-VGSDRSWVYACTADIAEGEAEAFTFAIRFGSKENADKFKEEFEKA-QEINKKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0B4K7J2-1", "uniprot_id": "RBP2_DROME", "id": "A0A0B4K7J2-1", "name": "E3 SUMO-protein ligase RanBP2", "aln": "MFTTRKEVDAHVHKMLGKLQPGRERDIKGLAVARLYMKVQEYPKAIEYLNGYLRVRDDAVGHNMIATCYSRLNPPDVTEALQHYQRSIQIDPRQSEVVIDACELLVKENNASITECARYWLDQANSLDLSGNKQVFNLRMRVNLADSNGERDDTSGGDGEQNTLEILMYKELQARPQDVNIRIQLLRSYVEKMKIDQAFNYALKTELESKNCTSQSNEWYEQIWMVLFKIEMAKDVKKNWRFWHFALHTLDRLVQLSLEGSGLADSSKQLFRLDQYLFKFSTSIERSGDAPQRDLHQACIDHFTGQLLLHAVTLIFKREVLANKNKWMSTLRSALPLLLLGYQVRPIDDSSTNQWIKHCDAEQKQLIQMWRPQGAFRCAQLGRTLLGCLDRSQMEIKNDRENAEFDENKNSGNSMPGLFADSEELLASAHQQCLDKSWRSQIYQQLFTHAEHKLKDTSSHLVRNLRLQLPLFEWPNLAHIENYELQALVLPPHSLAQHVYLALGTDPNKLGDAPRVVFYEGFQRDVKQNLNYCGQDSISQVDVDLYLYATTIQTRRKLQIQREVYDSSNLGNRNAAARPHMMPFANLVGQLGAPEQSNWWDLVVRLNSNQLITEGNRAEQRAQLQHGLEAVRGVNGPKADAIIIFQLGKILNSRSDRSSLEARIDTLYRQGFSILRHQHNQQMESYVRVFKYGSAGSTAAWQDLQSLAEEAVTYFSEKMFRIGQYEQFLDEVRGLHLPMAYFLQSEACHHLEESSKLPRTSRDRYSERRRECLQKTQKLIKNDDKHPLIAAMHRHQQDRNSRGIDNSFGSPDVHNNSSAYEDAEDDFYSHAAFSANRSRRQLEVTPVTPIVMAQPSQEMEQAVKQISKSLCVLKDDVSVGMEAMRQDIKVLTEKFTGLEDLLKKIKISSRDTPTRDVDPAAALGLDDLFIIEDALAEHQQQQQHQQQQSHNQGAIHPVVPNPYTSGFYNGMPNTPSAQERFLQGPYGSPMFNQNQMYNYYAAQAQAQAQAQFLRTPPAPGSIPPPNMFGPRNPNFGLPSMFPPPTVPSVAPYIDAMGNFTQPPPSLIPPPAQPAAPPAPLNILESKPVVALPTPGFFNTTTPVFGASPIQVPQSKPLTVPTVPIPSTAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQPTLSVTIPAQHIKPSLVQAPEQPAQSAQPAQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEEAEQNQSGATDPNKTLPQDTSADDYDPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVD----KEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFKSFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSAAPATSAPASATPFASFSFTPNGSSGFGTSTASPFGNLSFGTASAVGSGNNTTLFTTALIKDNTVQGKTLQQESQLNKSNSSDAEEEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNKVRLLMRREQVHKLCCNQRLLPETKFTYATNCKAAVTWGAQDYSDEELTTALLAVRFKSQDICQQFLEAVQKAQQSIGNEPKKEEVPSAAGEKEKPIKGFGDAFKPKAGSWNCQACYTNNGQDQLYCLACQEPKDATVPPKQSGLDQGNALNLTTSSSNKFSFGFASSATLPATGGFSFGGATQPKEKPAVAVVTASASAPTSVQTAALGFGKSSMTSGFGDAFKPAVGSWSCSACYVNNPGESLYCSACDAPKNDTVPQKEKSLGSGLNLPPTSKFSFGFGAAAAGDKDQAGDGATFNFAAMPAAVAPTTSIGSSSFTFSMTKPKPDQQQPNSTAAKEDEDNDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESDWKERGLGDVKILRHRQTKKLRVVMRREQVFKICLNHVLNENVVYREKTETSWMFAVHDFSEGESVLERFTLRFKNKEVAQGFMEAIKNALNETAKPIEDSPVVGSVSQSTEANKPSQKNDGAAKSRGGESEVLDVGKTSSVRPTTHEVIPPLPMTLPLLTLPQPLAKPNDYQTPATILFKGSSLSRNNSSASEASKTPSSAFIFGSTDKSEPGKDAGPLANLQKLASGEGQGNVLGSIFRSGSSNENSSDGSVKFFFGGGNKAAEQQKKDSSESVFGGNKADSQSPATQEAPKLAFGGIAAPVFGDANPFGGHKVNLQKSDGKEEPKSIIGGTPLLFGGSNAFGIPKIETQSPAKDFVFGSAPAFGQMATFSFTAAKNEKEKDITSNNTTDLKAEGKEKKELVPETTSTFADLAKTGSTFADLASNPGGTFADLANKTGNDFANLSANSQGTTVGFNKSAGGGFYNLTHQNAFKNFESPQATEECDDDGDATTDDNYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVLEHPELQTFRLIMRQEQIHKLVLNMNISASLQMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTVNSCIKRAKALQGDEENKNDDAPEEQASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: ::..: . * ... * .*:*:: * : :::* **.*: :. ******: ******** *:* .* .. *:*****:* *:**** *:. :: ..*: : *:*: : :** . * *::*: * :. : :.: ", "identical_positions": 48, "similar_positions": 55, "identity": "1.76%" }, { "cls_id": "homologset.agr.SGD:S000002411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXE6-1", "uniprot_id": "XRCC3_MOUSE", "id": "Q9CXE6-1", "name": "DNA repair protein XRCC3", "aln": "--------MDLDQLDLNPRIT--AAVKRGRLKSVKEILCYSGP--------DLQRLTGLPSHDVQCLLRAASLHLRGSRVLSALHLFQQKESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGCSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIAQQRRLRTDAPEELIEKIRFSNHIFIEHAADVDTLLECVSKKVPILLSR--GMARLVVVDSIAAPFRCEF---HLQASAIRAKLLLSLGATLRRLSSTFRSPVLCINQVTDM-----------------------------------------------------------------------------------------VEDQQSVSRSLGASEERLSPALGITWANQLLMRLMVDRTHEDDVTT-------------GLPRSPVRTLRVLFAPHLPLSSCCYTVSGEGIRGMPGTQSY---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5N4-1", "uniprot_id": "D4A5N4_RAT", "id": "D4A5N4-1", "name": "DNA repair protein", "aln": "--------MDLDQLDLNPRIT--AAIKRGRLKSVKEVLCYSGP--------DLQRLTSLPSHDVQLLLRAAALHLRGSRVLTALHLFQQRESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGRSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIEQLQELRTDVPGEVTQKIRFGNHIFIEHAADVDTLMECVSKRVPILLSR--GMARLVVVDSIAAPFRCEF---HLQASAVRAKHLHSLGAALQRLSSTFRSPVLCINQVTEM-----------------------------------------------------------------------------------------VEDQE----SAGAWEERLSPALGITWANQLLMQLMVDRIHEDSVTT-------------GLPRSPARTLRVLFAPHLPLSSCCYTVSGEGVRGMAGTESC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43542-1", "uniprot_id": "XRCC3_HUMAN", "id": "O43542-1", "name": "DNA repair protein XRCC3", "aln": "--------MDLDLLDLNPRII--AAIKKAKLKSVKEVLHFSGP--------DLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSR--GMARLVVIDSVAAPFRCEF---DSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEA-----------------------------------------------------------------------------------------MEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAAL-------------GCP---ARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77135-1", "uniprot_id": "O77135_DROME", "id": "O77135-1", "name": "", "aln": "--------MTNFLDQLPKHIR--EIAEQVNVLAPEEVLTTPKVRFLDTRQQSLHTIVRKCTPDDVRVLKDAAAKWLAEMPQSADSLFKP--LVNVRWSRVSFGCSALDRCTGGGVVTRGITELCGAAGVGKTQLLLQLSLCVQLPRELGGLGKGVAYICTESSFPARRLLQMSKACEKRHPEM------ELNFLGNIFVENHIEAEPLLACVINRIPRLMQQ--HGIGLIIIDSVAAIFR------LYNDYLERARHMRRLADALLSYADKYNCAVVCVNQVATR-----------------------------------------------------------------------------------------DGQDE-------------IPCLGLQWAHLGRTRLRVSRVP-KQHRM-------------GDQLITVRKLEILYSPETPNDFAEFLITAEGVVNVPEPSVPSPPAKMRRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25301-1", "uniprot_id": "RAD57_YEAST", "id": "P25301-1", "name": "DNA repair protein RAD57", "aln": "MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQRLESMLSSRPAYEKLG--------ITQSNIFTVSCNDLINQEHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAYQITKRGIETA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* .: .. : : : :. . ::: : . .: . .:* **: *** : * :..**:** :**.*.**:.. *** .** **. :* :** .: . .:** : : ::* *:.: *:::**:: :* . . . : :. * : : .*: *** .. * **: *:: :: .: . . *.:.:: :. . : :: .*: ", "identical_positions": 46, "similar_positions": 90, "identity": "9.52%" }, { "cls_id": "homologset.agr.SGD:S000002412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIH0-1", "uniprot_id": "MAF1_RAT", "id": "Q5XIH0-1", "name": "Repressor of RNA polymerase III transcription MAF1 homolog", "aln": "MKLLENSSFEAINSQLTVETGDAHIIGRIESYSCKMAGDDKHMFKQFCQ----------EGQPHVLEALSPPQT----------------------------SGLSPS-RLSKSQGGEDESP-------------------------------------------------------------------------------------------------------LSDKCSRKTLFYLIATLNESFRPDYDFSTARSHEFSREPSLRWVVNAVNCSLFSAVREDFKALKPQLWNAVDEEICLAECDIYSYNPDLDSDPFGEDGSLWSFNYFFYNKRLKRIVFFSCRSISGSTYTPSEAGNALDLELGAEEVDEESGGGGGGGEGRAEETSTMEEDRVPVICM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0U6-1", "uniprot_id": "MAF1_MOUSE", "id": "Q9D0U6-1", "name": "Repressor of RNA polymerase III transcription MAF1 homolog", "aln": "MKLLENSSFEAINSQLTVETGDAHIIGRIESYSCKMAGDDKHMFKQFCQ----------EGQPHVLEALSPPQT----------------------------SGLSPS-RLSKSQGGEDESP-------------------------------------------------------------------------------------------------------LSDKCSRKTLFYLIATLNESFRPDYDFSTARSHEFSREPSLRWVVNAVNCSLFSAVREDFKALKPQLWNAVDEEICLAECDIYSYNPDLDSDPFGEDGSLWSFNYFFYNKRLKRIVFFSCRSISGSTYTPSEAGNALDLELGAEEADEESGGGG--GEGRAEETSTMEEDRVPVICM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H063-1", "uniprot_id": "MAF1_HUMAN", "id": "Q9H063-1", "name": "Repressor of RNA polymerase III transcription MAF1 homolog", "aln": "MKLLENSSFEAINSQLTVETGDAHIIGRIESYSCKMAGDDKHMFKQFCQ----------EGQPHVLEALSPPQT----------------------------SGLSPS-RLSKSQGGEEEGP-------------------------------------------------------------------------------------------------------LSDKCSRKTLFYLIATLNESFRPDYDFSTARSHEFSREPSLSWVVNAVNCSLFSAVREDFKDLKPQLWNAVDEEICLAECDIYSYNPDLDSDPFGEDGSLWSFNYFFYNKRLKRIVFFSCRSISGSTYTPSEAGNELDMELGEEEVEEESRSGG----SGAEETSTMEEDRVPVICI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGU2-1", "uniprot_id": "MAF1_DANRE", "id": "Q6PGU2-1", "name": "Repressor of RNA polymerase III transcription MAF1 homolog", "aln": "MKLLENSSFEAINSLLTIETGDCKIIGRIESYSCKMAGDDKQMFKQFCQ----------EGQPHVLEALSPPQS----------------------------SGISPN-KLSHSLD-DGEGP-------------------------------------------------------------------------------------------------------LSDKCSRKTLFYLIATLNESFRPDYDFSRTKGHDFSKEPSVNWVFNAVNSSLSAAAGEAYSHLQPQLWEALDKEISLAECDIYSYNPDLDSDPYGEEGNLWSFNYFFYNKRLKRIVFFTCRSVS-LFMAPRDSGIGTELDLELDEGSYE-----------EEEEGNMDEERYGALCA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PL26-1", "uniprot_id": "Q7PL26_DROME", "id": "Q7PL26-1", "name": "Repressor of RNA polymerase III transcription MAF1", "aln": "MKLLESSRFEAINNALSIQTSGITIFGRIESYSCKMVAAEKVLYKRFTA----------DSHGHDLQALSPPQTL---------------------------ADFSPNFRRNNSQSGDEGIT-------------------------------------------------------------------------------------------------------LCDTISRKTLFYLIATLNASFEPDYDFSEAKSHEFSKEPSLQWVMNSIHANLSALAGDKYQAIRQPLWSAVDDEVILSECDIYSYNPDLSCDPFGEPGCLWSFNYFFYNKKLKRIVFFTSRAVN-SLYAG------------------------------ETLPFSMEEEVY------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41910-1", "uniprot_id": "MAF1_YEAST", "id": "P41910-1", "name": "Repressor of RNA polymerase III transcription MAF1", "aln": "MKFIDELDIERVNQTLNFETNDCKIVGSCDIFTTKAVASDRKLYKTIDQHLDTILQENENYNATLQQQLAAPETNQSPCSSPFYSNRRDSNSFWEQKRRISFSEYNSNNNTNNSNGNSSNNNNYSGPNGSSPATFPKSAKLNDQNLKELVSNYDSGSMSSSSLDSSSKNDERIRRRSSSSISSFKSGKSSNNNYSSGTATNNVNKRRKSSINERPSNLSLGPFGPINEPSSRKIFAYLIAILNASY-PDHDFSSVEPTDFVKT-SLKTFISKFENTLYSLG----RQPEEWVWEVINSHMTLSDCVLFQYSPSN-SFLEDEPGYLWNLIGFLYNRKRKRVAYLYLICSRLNSSTGEVEDALAKKPQGKLIIDDGSNEYEG-EYDFTYDENVIDDKSDQEESLQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:::. :* :*. *..:*.. *.* : :: * .. :: ::* : : : : *:.*:: : ... . .:* . . : : *** : **** ** *: **:*** .. :* : *: ... .. .* : . :*..::..: *::* ::.*.*. . .* * **.: *:**:: **:.:: . : :::. ", "identical_positions": 45, "similar_positions": 89, "identity": "11.17%" }, { "cls_id": "homologset.agr.SGD:S000002413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI00-1", "uniprot_id": "TCP11_RAT", "id": "Q5XI00-1", "name": "T-complex protein 11 homolog", "aln": "------------------------------------------------------------------------------------------------------------------MPDLKER------AARKEPGAA----------------ESASRESRGGNTRESASSAQGHRSRRFNRRSSTAALTPGSAQGRGVQTAPRAPVGHGGLRTGLTSRCPQ--------------PSARAKLPSVTRGAPLPPSPGKGHFGATPISHRLGLTERVHD---------ASKLDCHLEDR-KSASSL---------------------------------------------------------------------------------------------------------ESRGKEVMPSDFWDHLKEQLSAV---PPDFSCALELLKEIKEILLSLLLPRQ-SRLRNEIEEALDMEFLHQQADRGDLNVSYLSKYILNMMVLLCAPVRDEAVQRLE---------NIS-DPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSIQFERAQFQERLNKDPS--LLNHTTKWLTQAATQLIAPSGSCYDIQDPSS-SSGPSPSDIA-IPEPLSPAMVLSQGFLNLLTWDPENEEFPETLLADRSRLQELESQQNQLTILASVLLVASSFSGSVLFGSPQ---------FVDRLKRITKSLVEDFNS---RPEEVMQTVSDQVTEEIHQSLKNMG------------LSPLSSENTDSLIGQLQNIAKKENCVRSVIDQRIHLFLKCCFVLG-----------------------------------------------VQRSLLDLPGG---------LSLIEAELAELGQKFVSLTHHNQQVFAPYYTEILKTLINPVQTLTTKVGSL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01755-1", "uniprot_id": "TCP11_MOUSE", "id": "Q01755-1", "name": "T-complex protein 11", "aln": "------------------------------------------------------------------------------------------------------------------MPDVKER------AARKEPGAA----------------ESASRESRGGNTRESASSARGT-DRVGSTVARARPPSPQGPRRGAVKTAPRGPVGHGGLRTGPTSRCPQ--------------PSARAKLPSVTRGAPLPPSPGKGHLGGTPSSHRLGMTERVHD---------ASKLDCQLEERSLSSSSL---------------------------------------------------------------------------------------------------------KGKVKDTMPSDFWEHLNEQLSAV---PPDFSCALELLKEIKEILLSLLLPRQ-SRLKNEIEEALDMEFLQQQADRGDLNVSYLSKYILNMMVLLCAPIRDEAVQRLE---------NIS-DPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSVQFERAQFQERLNKEPR--LLNHTTKWLTQAATQLIAPSASSSDLQDCSS-SAGPSPSDVA-VPEPLSPAMVLSQGFLNLLTWDPENEEFPETLVADRPRLQELESQQSQLTILASVLLVASSFSDSGLFSSPQ---------FVDKLKQITKSLVEDFNS---RPEEVMQSVSEQVVEEVHQGLESMG------------LAALSSENTASLVGQLQNIAKKENCVRSVIDQRIHLFLKCCFVLG-----------------------------------------------VQRSLLDLPGG---------LTLIEAELAELGQKFVSLTHHNQQVFAPYYTEILKTLISPAQTLATKGGSL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWU5-1", "uniprot_id": "TCP11_HUMAN", "id": "Q8WWU5-1", "name": "T-complex protein 11 homolog", "aln": "------------------------------------------------------------------------------------------------------------------MPDVKES------VPPKYPGDS----------------EGRSCKP------ETSG-------------------PPQEDKSGSEDPPPFLSV------TGLTETVNE--------------VSK--------------------------LSNKIGMN-----------------CDYYMEEKVLPPSSL---------------------------------------------------------------------------------------------------------EGKVKETVHNAFWDHLKEQLSAT---PPDFSCALELLKEIKEILLSLLLPRQ-NRLRIEIEEALDMDLLKQEAEHGALKVLYLSKYVLNMMALLCAPVRDEAVQKLE---------NIT-DPVWLLRGIFQVLGRMKMDMVNYTIQSLQPHLQEHSIQYERAKFQELLNKQPS--LLNHTTKWLTQAAGDLTMSPPTCPDTSDSSS-VAGPSPNEAANNPEPLSPTMVLCQGFLNLLLWDLENEEFPETLLMDRTRLQELKSQLHQLTVMASVLLVASSFSGSVLFGSPQ---------FVDKLKRITKSLLEDFHS---RPEEAILTVSEQVSQEIHQSLKNMG------------LVALSSDNTASLMGQLQNIAKKENCVCSVIDQRIHLFLKCCLVLG-----------------------------------------------VQRSLLDLPGG---------LTLIEAELAELGQKFVNLTHHNQQVFGPYYTEILKTLISPAQALETKVESV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AEI7-1", "uniprot_id": "A2AEI7_MOUSE", "id": "A2AEI7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------MPKSEKI------ISKKDSSPS----------------ENGSPKP------ETSS---------------------KNQEDKTSSEVHSAENQLAAISNEDTGKVNE--------------VSKLN------------------------VASEIAI-----------------------EKNDLPEDSP---------------------------------------------------------------------------------------------------------ESQFVETMYNAFWDHLRDQLSQT---PPDFSCVLELIKNIKQILMALLLPRQ-NLLRNEIEEVLDLDLLKQETEHGALDILHLSHYILNLMALMCAPIRDEAVKELE---------NIK-DPVQLLRGIFQVLGLMKMDMVNYTIKNIRPYLQEHSIQYERAKFQELLDKQPD--RLDCTTKWMTRAATEIITSLSSLSVTSCISSGVISSFPT-PKPDPDPPSLTTVLYQGYLNLVLRDHGNEEFPETLLMDKARLQTMRSKFRHLTILASVLLVARSFSCGVLFSSPE---------FVDKLKCITKALTEDFSS---KPEESMLSVSEQVSQEIHQGLKDTG------------LTALSSENRASLVGQLRNIAKKENCIRIIIEQRMHLFLKCCLIRG-----------------------------------------------MQESLLDFPGC---------FLFIEPELAELGWKFVNLMHHNQHVFSPYYAEILKNIISTQ-NDEDEEKPIK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M6M6-1", "uniprot_id": "F1M6M6_RAT", "id": "F1M6M6-1", "name": "", "aln": "----------------------------------------------------------------------------MVYSMDSSTGEPQGFSVVRAATTGKGSQTPRTRRDTTNMPKTKKN------ISQKDSSPT----------------EIRVPKP------ETST---------------------KNQEDKTSSEVPFPENQPAAISKEDLGKVNE--------------VSKLS------------------------IAHEIVVN-----------------QDFIVEKNDLPENSL---------------------------------------------------------------------------------------------------------ESKFVETMYNAFWDHLKDQLSRT---PPDFSCALELIKNIKQILMSLLLPRQ-NRLRNEIEEALDLDLLKQETEHGALDVPHLSNYILNLMALMCAPVRDEAVQELE---------SIK-DPVQLLRGIFQVLGLMKMDMVNYTIKNIRPYLQEHSIQYERAKFQELLDKQPD--LLDCTTKWMTRAATELITSLPSISVSPSTSSGTISAFPS-PKPDPDPPSLTTVLYQGYLNLVLRDHGSEEFPETLLMDKARLQNMKSKLRHLTILASVLLVARSFSCGVLFSSPE---------FVDKLKCITKALTEEFSS---KPEESMLSVSEQVSQEIHQGLKETG------------LTALSSENRASLVGQLRNIAKKENCIRTIIEQRIHLFLKCCLIRG-----------------------------------------------MQESLLDFPGG---------LLFIEPELAELGWKFVNLMHHNQHVFSPYYAEILKNIISPPSTEENEEKPF------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B4DZS4-1", "uniprot_id": "T11X1_HUMAN", "id": "B4DZS4-1", "name": "T-complex protein 11-like X-linked protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MPKTEET------VLQNDPSVA----------------ENGAPEP------KTPG---------------------QSQKSKS----FCLDDQ----SPDLIETVNE--------------VSKLS------------------------ISHEIVVN-----------------QDFYVEETILPPNSV---------------------------------------------------------------------------------------------------------EGRFAEAMYNAFWNHLKEQLLST---PPDFTCALELLKDVKETLLSLLLPWQ-NRLRNEIEEALDTDLLKQEAEHGALDVPHLSNYILNLMALLCAPVRDEAIQKLE---------TIR-DPVQLLRGILRVLGLMKMDMVNYTIQSFRPYLQEHSIQYEQAKFQELLDKQPS--LLDYTTKWLTKAATDITTLCPSSPDSPSSSCSMVCSLPSGAGNNSEPPSPTMVLYQGYLNLLLWDLENVEFPETLLMDRIRLQELAFQLHQLTVLASVLLVARSFSGEVLFRSPE---------FVDRLKCTTKALTEEFIS---RPEETMLSVSEQVSQEVHQGLKDMG------------LTTLSSENTASLLGQLQNITKKENCIRSIVDQWIRFFLKCCLLHG-----------------------------------------------MQESLLHFPGG---------LILIEKELAELGWKFLNLMHHNQQVFGPYYAEILKHIIHPAQAQETDVEPN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTG3-1", "uniprot_id": "T11L1_MOUSE", "id": "Q8BTG3-1", "name": "T-complex protein 11-like protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MSENLDK------SHVDEAGEA----------------EAAASEQGLEGALECSDETLQK-------------KVKSDSPSSQRVGRPHSSPARLVTVEELLETAKG--------------VTNMA------------------------LAHEIVVT-----------------GDFRINAVELAEGSL---------------------------------------------------------------------------------------------------------EKRVKEIVHKAFWDCLSVQLSEE---PPTYDHAIKLVGEIKETLLSFLLPGH-TRLRNQITEVLDLELIKQEAENGALDISKLAEFIIGMMGILCAPARDEEVKKLK---------GIK-EIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERRKFQEVLERQPN--SLDFATQWLEEATNDLLSQKYKHALPAGGGAAGSGDAPL--------LTPVSVQNFAYLKLLKWDHFQRPFPETVLMDQSRFQELQLQLEQLAVLGAVLLVTFSTAAPGISGHAD---------FAEKLKMMVKTLLTDMHLPSFHLEDALASIGEKVCLEVSSCLSLCG------------SSPFSVAKETVLKGQIQALASPEDPIRRIMESRIFTFLETYLASG-----------------------------------------------HQKPLPTVPGG---------LGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6F1-1", "uniprot_id": "A0A0G2K6F1_RAT", "id": "A0A0G2K6F1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------MSENLDK------SHVNEAGES----------------KSAASEEGQKGALECSDEALQE-------------KVKSDSPSPLRVGRPHSSPPRLVTVEELLETAKG--------------VTNMA------------------------LAHEIVVN-----------------GDFRINAVELAEGSL---------------------------------------------------------------------------------------------------------EKRVKEIVHKAFWDCLSVQLSED---PPTYDHAIKLVGEIKETLLSFLLPGH-TRLRNQITETLDLELIKQEAENGALDISKLAEFIVGMMGILCAPARDEEVKKLK---------DVK-EIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPN--SLDFVTQWLEEASNDLLTQKCKHALPAGGGAAGSGDAPL--------LTAASVQNYAYLKLLKWDHFRRPFPETVLMDQPRFQELQLQLEQLALLGAVLLVTFSTSAPAVSGHAG---------FAEKLKTVVKILLADVHLPSFQLEDALTSIGEKVCLEVSSCLSMCG------------SSPFSVSKETVLKGQIQALASPDDPIRRIMESRILTFLETYLASG-----------------------------------------------HQKLLPTVPGG---------LGPIQKELEEVAVKFVRLVNYNKMVFCPYYDEILSKLLLRS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUJ3-1", "uniprot_id": "T11L1_HUMAN", "id": "Q9NUJ3-1", "name": "T-complex protein 11-like protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MSENLDK------SNVNEAGKS----------------KSNDSEEGLEDAVEGADEALQK-------------AIKSDSSSPQRVQRPHSSPPRFVTVEELLETARG--------------VTNMA------------------------LAHEIVVN-----------------GDFQIKPVELPENSL---------------------------------------------------------------------------------------------------------KKRVKEIVHKAFWDCLSVQLSED---PPAYDHAIKLVGEIKETLLSFLLPGH-TRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLK---------DIK-EIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPN--SLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPR--------LSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQAD---------FAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCG------------SSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASG-----------------------------------------------HQKPLPTVPGG---------LSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K1H7-1", "uniprot_id": "T11L2_MOUSE", "id": "Q8K1H7-1", "name": "T-complex protein 11-like protein 2", "aln": "------------------------------------------------------------------------------------------------------------------MPFNGEK------QCVSEDQQS----------------DSESSRFAEGVASLSDYECSRQ-------------SFTSDSSS-KSSSPASTSPPRGLMFDDVMAAAKN--------------LSDMT------------------------LAHEIAVN-----------------ENFQLKQNALPENSL---------------------------------------------------------------------------------------------------------AGQVKRVVHQAFWDVLEADLSAE---PPQYEYAIKLFEEIREILLSFLTPGG-NRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVITTMGKICAPVRDEDIRELK---------ATT-NIVEMLRQIFRVLDLMRMDMMNFVIRNIRPHIQHHLVEYERNKFQEVVEETPN--ALSQTTEWLKESIDKELL--SETDVAPA---AEHSSTPS--------LSPLLVLNNCYLKLLQWDYQKKVLPETLMTDGPRLQELSEKLNQLKMTACVALITNNMVGAVTEGLPE---------LANRLKRISAVLLEGMNKETFNLKEALHSIGVQTCAEVNKALEERG------------SPTLNAEVQANLVGQLSSLEEKDNPVCTLMDKRIQLYMKGLLCLPS----------------------------------------------TQKSMPPVPGG---------LDVIQRELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAVGKIDASLPTN---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q568Z0-1", "uniprot_id": "T11L2_RAT", "id": "Q568Z0-1", "name": "T-complex protein 11-like protein 2", "aln": "------------------------------------------------------------------------------------------------------------------MPFNGEK------QYVNEDQQS----------------DSESSRFSESTASLSDYGCSRQ-------------SFTSDSSS-KSSSPASTSPPRGIMFDDVMAAAKN--------------LSDMT------------------------LAHEIAVN-----------------ENFQLRPNALPENSL---------------------------------------------------------------------------------------------------------AGQVKRVVHQAFWDVLEADLSAE---PPQYEYAIKLFEEIREILLSFLTPGG-NRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVISTMGKICAPVRDEDIRELK---------ATT-NIVEMLRQIFRVLDLMRMDMTNFVIRNIRPHIQHHLVEYERNKFQEVLEETPN--ALSQTTEWLKESIDKELF--SETDVAPG---AEHSSTPS--------LSPLTVLNNCYLKLLQWDYQKNVLPETLMTDGPRLQELTEKLNQLKMIACVSLITNNMVGAVTEGLPE---------LANRLKRISAVLLEGMSKQTFNLKEALNSIGVQTCAEVNKALKERG------------SPTLNAEVQANLVGQFTSLEEKDNPVCALMDKRIQLYMKSLLCLPS----------------------------------------------TQKSRPPVPGG---------LDVIQQELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAMGKIDASLPTN---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4U5-1", "uniprot_id": "T11L2_HUMAN", "id": "Q8N4U5-1", "name": "T-complex protein 11-like protein 2", "aln": "------------------------------------------------------------------------------------------------------------------MPFNGEK------QCVGEDQPS----------------DSDSSRFSESMASLSDYECSRQ-------------SFASDSSS-KSSSPASTSPPRVVTFDEVMATARN--------------LSNLT------------------------LAHEIAVN-----------------ENFQLKQEALPEKSL---------------------------------------------------------------------------------------------------------AGRVKHIVHQAFWDVLDSELNAD---PPEFEHAIKLFEEIREILLSFLTPGG-NRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDNDIRELK---------ATG-NIVEVLRQIFHVLDLMQMDMANFTIMSLRPHLQRQLVEYERTKFQEILEETPS--ALDQTTEWIKESVNEELFSLSESALTPG---AENTSKPS--------LSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKIIACLSLITNNMVGAITGGLPE---------LASRLTRISAVLLEGMNKETFNLKEVLNSIGIQTCVEVNKTLMERG------------LPTLNAEIQANLIGQFSSIEEEDNPIWSLIDKRIKLYMRRLLCLPS----------------------------------------------PQKCMPPMPGG---------LAVIQQELEALGSQYANIVNLNKQVYGPFYANILRKLLFNEEAMGKVDASPPTN---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGW3-1", "uniprot_id": "Q5RGW3_DANRE", "id": "Q5RGW3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------MPLNDERPTSTSSTVASEDQSS----------------DTESSERCDSLTSSSDVDCSRQ-------------SFTSDSSS-KHNSPS-CSPPKILTLDEVMASARD--------------LSNLS------------------------LAHEIVVN-----------------RNFHLEPPDLPQNSL---------------------------------------------------------------------------------------------------------EKRVKDMVHKAFWDCLESELNDD---PPEYDYAIKLLEEIRDTLLSFLNPGA-NRLRTQIMEVLDMDLIRQQADNNAVDIQGLVSYIINTMGKFCAPVRDDEIKKLK---------ENSGDCVTLFKEIFRVLDLMKMDMVNFTIQSFRPELQRQSVEYERAKFQSILERTPN--ALEHTTEWIKSSIEEATQIMPPAEKSSD---SGQSGRPL--------PGPSLVLNTAYIKLLTWDDSKGPLPETVMTDEARLQVMQRSLQLYQTVASVLLIVYSSIGGAVSGLPA---------LAERLKKMTVVLLEGMHNTEFKLNEALGNVSVQICCEVNKSLAERN------------FPALPDELQATLKGQICDVTQENNPVRTLVEGRVQQYLWVVLSSSS----------------------------------------------SHRTPPPVPPG---------LTLIQQELMPLSLSFANLVNFNKKVYGPFYFSILKSLLFSDTQN-HIPPGPPSSPLKSK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W461-1", "uniprot_id": "Q9W461_DROME", "id": "Q9W461-1", "name": "T-complex protein 11-like protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MDAQENR--------SEQSGQS----------------GDHEEHEERRIRTDSES--------------------SVESMTRFVLPSLDGTPPKIVTLDEVSSMFKN--------------LRNME------------------------LAHEIALN-----------------PDFKLQKYEPPSDSL---------------------------------------------------------------------------------------------------------EGAIKKMVHKAFWDLLRVQLDRQ---PPSYDQAIRLLAEIKECFPQLLSPNN-ERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVAALR---------KID-DVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLREFHGNVGFPATEDWLQRHRSGS--------------------------------SDDETIYNAYMQLIDYP-ADKEFPELLRIDKERFAGLSWRAQRLILCASLISVAQGMP--IISQRRE---------NRIKLAQQLDIIVQDIKNQD-QVASTIESCYEQIRSFVNKALEQEN------------LPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLRSN-------------------------------------------------GSIPPPPSG---------FADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQTAKP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40317-1", "uniprot_id": "SOK1_YEAST", "id": "P40317-1", "name": "Protein SOK1", "aln": "MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKPSSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSDLLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKEQAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTPSGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTATSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRHDIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLFDTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMRDPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAVEFEKQYFNTLIASKRVN--LNTSLLWFDKKFNENVTAGLVRNPSSIT-----------------IPDVYNICIRSIINLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATKEYVIHTYSTKRLKNEIISIITDEHG-NCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCEQARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDGRVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRGLFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . .: : . . : . :*: : :: * : . : : : .* . * :.** .. *: .. : . :: : *:* ** : : : :: :: :: *::*: *. : :. : : :::*: *. : : *: ::*: * : * *: : : :* : . . . : : . . .: . . . . : :: : : : * *: . : : *: .: :: : ", "identical_positions": 26, "similar_positions": 99, "identity": "2.76%" }, { "cls_id": "homologset.agr.SGD:S000002416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIG6-1", "uniprot_id": "GALK2_RAT", "id": "Q5XIG6-1", "name": "N-acetylgalactosamine kinase", "aln": "----MAAEDPATRRVQVAEHPRLLKLKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDMLIAVGPV--KTQTLQLANTDPLYP----DFSTTANNICIDKTQPLWHNYFLCGFKGIQ--------EHFGLTQLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---MRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATDVKLPSG----AVFVIANSCVEMN--KAATSHFNVRVMECRLAAKVLAKHKGLQWDKVLR------------LEEVQSELG--------------ISLEEMLLVTEDALHAEP--YSREEICKCLGISLEELRTQILSPNTQGELTFKLYQRAKHVYSEAARVLQFKQVCEAAP----DNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVP---ADTLSSFLASVHEAYYQGNMSRLARE--KHSLFATKPGGGALVFLEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FH4-1", "uniprot_id": "GALK2_MOUSE", "id": "Q68FH4-1", "name": "N-acetylgalactosamine kinase", "aln": "----MAAEDPATRRVQVAEHPRLLKLKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVIPMAVEQDMLIAVEPV--KTHTLQLANTDPLYP----DFSTTANNICIDKTKPLWHNYFLCGFKGIQ--------EHFGLSKLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---LRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATNVKLPSG----AVFVIANSCMEMN--KAATSHFNVRVMECRLAAKVLAKHKGLQWDNVLR------------LEEVQSKLG--------------ISLEEMLLVTEDALHPEP--YSREEICRCLGISLERLRTQILTPNTQDELTFKLYQRAKHVYSEAARVLQFKQVCEDAP----DNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVP---ADMLSSFLASVHEAYYQGNTSRLAQE--KHSLFATKPGGGALVFREV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01415-1", "uniprot_id": "GALK2_HUMAN", "id": "Q01415-1", "name": "N-acetylgalactosamine kinase", "aln": "----MATESPATRRVQVAEHPRLLKLKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPV--KTYALQLANTNPLYP----DFSTSANNIQIDKTKPLWHNYFLCGLKGIQ--------EHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---RNLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATDVKLPSG----AVFVIANSCVEMN--KAATSHFNIRVMECRLAAKLLAKYKSLQWDKVLR------------LEEVQAKLG--------------ISLEEMLLVTEDALHPEP--YNPEEICRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHVYSEAARVLQFKKICEEAP----ENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVP---ADKLPSFLANVHKAYYQRSDGSLAPE--KQSLFATKPGGGALVLLEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13045-1", "uniprot_id": "GAL3_YEAST", "id": "P13045-1", "name": "Protein GAL3", "aln": "MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLS--SAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ....* : : . : * : : * ..: *.* .*:*****:********.:**:*:*:: *:* ** : *. :: *:*::* :. *:. .. : ** : . * *** **:: : *:*. : * * : : :.:**...*** **:.*.*.*.*: . :** :*:.* * :*:*:*.:.*****: *. .**. * :** * *:** .*:*. *****: :: * ::*.:::*:**:* :**: **. .: . :: :. * :** :.*::: : :. .* . .*. * *.: : *:. . :************: ***: :: *. :: . :*.***:*: ** .:***** * :*: .*. *: *************: :** . : .. : : :*: *: * *.:::.:**. *: : : ", "identical_positions": 158, "similar_positions": 163, "identity": "30.21%" }, { "cls_id": "homologset.agr.SGD:S000002419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50878-1", "uniprot_id": "RL4_RAT", "id": "P50878-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHCVEEVPELPLVVEDKVESYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAAAALAAKSEKIVPEKGAGDKKPAVGKK---GKKP-VDAKKLKKPAG--------KKVVTKKPAEKKPTTEEKKSAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8E6-1", "uniprot_id": "RL4_MOUSE", "id": "Q9D8E6-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAATALATKSEKVVPEKGTADKKPAVGKK---GKK--VDAKK-QKPAG--------KKVVAKKPAEKKPTTEEKKPAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36578-1", "uniprot_id": "RL4_HUMAN", "id": "P36578-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAALQAKSD---EKAAVAGKKPVVGKK---GKKAAVGVKKQKKPLVGKKAAATKKPAPEKKPAEKKPTTEEKKPAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09180-1", "uniprot_id": "RL4_DROME", "id": "P09180-1", "name": "Large ribosomal subunit protein uL4", "aln": "MSLGNARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASGVPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMRDRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLNDLFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRS--VRRLNPLTNVRQLIKLNPYAEVLKRRAALAAEKRTVAKVLAKAKKQNVELAKSH----FANVATKAAANRAKLLAARK---------------------KKVAAKKPAAKK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49626-1", "uniprot_id": "RL4B_YEAST", "id": "P49626-1", "name": "Large ribosomal subunit protein uL4B", "aln": "----MSRPQVTVHSLTGEAT-ANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGS-ETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVF---AAEKLGSKKAEKTGTKPAAVFAETLKHD-------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** ::*:: ..*.: : : *****.******:*: *. :.:*:**.***** ********************** **** **********************:*:*: :** .::*** **:**:.:.:** ::** :: :.*:****. .:: :***:** *: : *: ** *:::***:*. *:** **** ::* :*:*: **:**:**: ** .**:*:****.*:*** ****:** :*::::*: .. :: * .*.** : .:*::*:::* **: .:* . : : * : ***.* : :::*****:.: : . :. . * . ", "identical_positions": 165, "similar_positions": 110, "identity": "37.67%" }, { "cls_id": "homologset.agr.SGD:S000002420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14691-1", "uniprot_id": "PSF1_HUMAN", "id": "Q14691-1", "name": "DNA replication complex GINS protein PSF1", "aln": "------MFC-------EKAMELIR-ELHRAPEGQLPAFN----------EDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIPTIK--FRHCSLLRNRRCTVAYLYDRLLRIRALRWEYGSVLPNALRFHMAAEEMEWFN---NYKRSLATYMRSLGGDEGL--DITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHILS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZ15-1", "uniprot_id": "PSF1_MOUSE", "id": "Q9CZ15-1", "name": "DNA replication complex GINS protein PSF1", "aln": "------MFC-------EKAMELVR-ELHRAPEGQLPAFN----------EDGLRQVLEEMKALYEQNQSDVNEAKSAGRGDLIPTVK--FRHCALLRNRRCTIAYLYDRLLRIRALRWEYGSVLPNSLRFHMSAEETEWFN---HYKKSLATYMRSLGGDEGL--DITQDVKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHVLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M5L5-1", "uniprot_id": "A0ABK0M5L5_RAT", "id": "A0ABK0M5L5-1", "name": "DNA replication complex GINS protein PSF1", "aln": "------MFFRF--VILNKKLYFQRKEREGGRDREKFLFKTAYILFLMQKEDGLRQVLEEMKALYEQNQSDVNEAKSAGRGDLIPTIK--FRHCSLLRNRRCTIAYLYDRLLRIRALRWEYGSVLPNPLRFHMSAEEVEWFN---HYKKSLATYMRSLGGDEGL--DITQDVKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W0I7-1", "uniprot_id": "Q9W0I7_DROME", "id": "Q9W0I7-1", "name": "DNA replication complex GINS protein PSF1", "aln": "MSRQTKMFG-------EKAFDLLK-ELERSSQ-TIPAFD----------DDGVRQVLEEIKAIFEENVAQASSYNASGDRSLWPLLN--FRHAALQRNKRCLLAYLYERCRRIKALRWEFGPIIPGDIKQALCEPEVTFFN---NYSKSLAAYMCSAGYNQGLPIDLTNNLRPPKSLYIEVRCMEDYGKFELDDGEVIHLKKNSQHYLPRAQVESLVRQGILHHIA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KVC2-1", "uniprot_id": "Q7KVC2_DROME", "id": "Q7KVC2-1", "name": "Kinesin motor domain-containing protein", "aln": "------------------------MDISGGNTSRQPQKK----------SNQNIQVYVRVRPLNSRER----CIRSAEVVDVVGPRE--VVTRHTLDS-KLTKKFTFDRSFGPESKQCDVYSVVVSPL-------IEEVLN---GYNCTVFAYGQTG-----------NNLRPPKSLYIEVRCMEDYGKFELDDGEVIHLKKNSQHYLPRAQVESLVRQGILHHIA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12488-1", "uniprot_id": "PSF1_YEAST", "id": "Q12488-1", "name": "DNA replication complex GINS protein PSF1", "aln": "------MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYH----------EDIIRNILKEVSNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAWNNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSDVFIDVRVLKDAGEIQTEYG-VFNLIKDSQFFVRQSDVERLIQQGYLQKI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :: .: : .. . . . : . . : : * : : : : * .: **..::*:** ::* *::: : * . * *:**.:: : . * *::** *.:: ", "identical_positions": 19, "similar_positions": 47, "identity": "8.37%" }, { "cls_id": "homologset.agr.SGD:S000002424", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESM0-1", "uniprot_id": "IP6K1_RAT", "id": "Q9ESM0-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISR-------EQRFYESLP---PEMKEFTPEYK-------------------------------------------GVVSVCFEGDSDGYINLVAYPYVESETVEQDDTPEREQPRRK-----------------------------------------------------------------------------------------------------HSRRSLHRSGSGSDHKEEKASLSFETSESSQETKSPKVELHSHSDVPFQMLDSNS----------------------------GLS----SEKISYN----------------------------------------------PWSLRCHKQQLSRMRSE-------------------------SKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSASLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR-----------------------------------SELRLKHVDMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEVPPLCGPSTSPSNTSLEAGPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------PPKVDVRMIDFAHSTFKGFR-----------------------DDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD10-1", "uniprot_id": "IP6K1_MOUSE", "id": "Q6PD10-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISR-------EQRFYESLP---PEMKEFTPEYK-------------------------------------------GVVSVCFEGDSDGYINLVAYPYVESETVEQDDTPEREQPRRK-----------------------------------------------------------------------------------------------------HSRRSLHRSGSGSDHKEEKASLSFETSESSQEAKSPKVELHSHSDVPFQMLDSNS----------------------------GLS----SEKISYN----------------------------------------------PWSLRCHKQQLSRMRSE-------------------------SKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR-----------------------------------SELRLKHVDMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEVPPPCGPSTSPSSTSLEAGPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------PPKVDVRMIDFAHSTFKGFR-----------------------DDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92551-1", "uniprot_id": "IP6K1_HUMAN", "id": "Q92551-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISR-------EQRFYESLP---PEMKEFTPEYK-------------------------------------------GVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRK-----------------------------------------------------------------------------------------------------HSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNS----------------------------GLS----SEKISHN----------------------------------------------PWSLRCHKQQLSRMRSE-------------------------SKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCL---------------------------DRRSEMRLKHLDMV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEVASSCGPSTSPSNTSPEAGPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------QPKVDVRMIDFAHSTFKGFR-----------------------DDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RE97-1", "uniprot_id": "F1RE97_DANRE", "id": "F1RE97-1", "name": "Kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVPHTMEAGKHSASQGQGSCGGVPLEPFIHQVGGHTSMMRYDDHTVCKPLITR-------EQRFYESLP---PEMKEFTPEYK-------------------------------------------GVVLVCFEGDSDGYINLVAYPYEESEGLDHEELSERDQPRRK-----------------------------------------------------------------------------------------------------HSRRSLHRSS--SEHKEDRHAHDSDGNDNLQELKSPLLDLQLHSDVPFQMLDSNS----------------------------GLS----SEKISHN----------------------------------------------PWSLRCHKQQLSRMRSE-------------------------SKDRKLYKFLLLENVVHHFKYPCILDLKMGTRQHGDDASEEKAARQMKKCEQSTSATLGVRVCGMQVYQMDTGHYLCRNKYYGRSLSI-DGFRQALFQFMHNGTLLR--KDLFEPVLSKLCSLKAVLERQASYRFYSSSLLIIYEGKDPE-----------------------------------SADSWQKPSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPSAKENQATSSENPAASELHTPPQ-------------------------------------------------------------------------------------------------------------------------------------------------------------VLNVDVRMIDFAHSTFKGFR-----------------------DDQTVHDGPDRGYVFGLESLINILQEIREENQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4AEE6-1", "uniprot_id": "D4AEE6_RAT", "id": "D4AEE6-1", "name": "Kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVRHGSDKGKAG--------VGVPLEPFLHQVGGHLSVLRYDAYTVCKPLIFQ-------EQKFYESLP---LAMRRFTPQYK-------------------------------------------GTITVHLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQ-----------------------------------------------------------------------------------------------------TLQQTTSSEGSPC-----PLAQMAHSLKESAAKALLRSDCHLSTQA-SPLVESAV----------------------------GSQ----IERKGFN----------------------------------------------PWGLHCHQAHLSRLCSQ-------------------------YPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDKKSFLCKDKYYGRKLSV-EGFRQALSQFLHDGIRLR--TELLEPILRRLQALLTVIRSQSSYRFYSSSLLIIYDG-EPPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAPAPQTTQGS--TSG-STSGD-------------------------------------------------------------------------------------------------------------------------------------------------------------PAKVDVRMIDFAHTTYKGSW-----------------------NERTTYEGPDPGYIFGLENLIGILRDIQEGE-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWD2-1", "uniprot_id": "IP6K3_MOUSE", "id": "Q8BWD2-1", "name": "Inositol hexakisphosphate kinase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVRHSSDKGKIG--------VGVPLEPFLHQVGGHLSVLQYDAYTVCKPLVSQ-------EQKFYESLP---LAMKCFTPKYK-------------------------------------------GTITVRLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQ-----------------------------------------------------------------------------------------------------TLQQTTGSESSPC-----PLTQLARSLKESAAKVLLRSDCHLSTQA-SPLVESED----------------------------GSQ----VERKGFN----------------------------------------------PWGLHCHQAHLTRLCSQ-------------------------YPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSV-EGFRQALSQFLHDGTRLR--AELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDG-EPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTTQGS--TSGGVTSGD-------------------------------------------------------------------------------------------------------------------------------------------------------------PAKVDVRMIDFAHTTFKGSW-----------------------NEHTTYEGPDPGYIFGLENLIGILRDIQEGE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PC2-1", "uniprot_id": "IP6K3_HUMAN", "id": "Q96PC2-1", "name": "Inositol hexakisphosphate kinase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVQNSADAGDMR--------AGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSR-------EQRFYESLP---LAMKRFTPQYK-------------------------------------------GTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQ-----------------------------------------------------------------------------------------------------TLQQTTGSNGSDCTLAQWPHAQLARSPKESPAKALLRSEPHLNTPA-FSLVEDTN----------------------------GNQ----VERKSFN----------------------------------------------PWGLQCHQAHLTRLCSE-------------------------YPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSV-EGFRQALYQFLHNGSHLR--RELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAPGSPHPHEAPQAAHGSSPGG-------------------------------------------------------------------------------------------------------------------------------------------------------------LTKVDIRMIDFAHTTYKGYW-----------------------NEHTTYDGPDPGYIFGLENLIRILQDIQEGE-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0U1-1", "uniprot_id": "IP6K2_RAT", "id": "Q9R0U1-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRTMDVEP-----RTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPR-------EHQFYETLP---AEMRRFTPQYK-------------------------------------------GVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCEPKSK------------------------------------------------------------------------------------------------------LLRWT-NKKHHVLETEKSPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSV----------------------------EKKGTVSSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN-------------------------AKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------WPEVTLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPLG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-----------------------EDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V72-1", "uniprot_id": "IP6K2_MOUSE", "id": "Q80V72-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRTMDVEP-----RTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPR-------EHQFYETLP---AEMRRFTPQYKAVLIFVRCADEFGASGNIETKEQ--------------------GVVSVRFEEDEDRNLCLIAYPLKGDHGTVDIVDNSDCEPKSK------------------------------------------------------------------------------------------------------LLRWT-NKKHHALETEKNPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSV----------------------------EKKGNVSSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN-------------------------AKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------WPEVTLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPIG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-----------------------EDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHH9-1", "uniprot_id": "IP6K2_HUMAN", "id": "Q9UHH9-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRAMDVEP-----RAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPR-------EHQFYETLP---AEMRKFTPQYK-------------------------------------------GVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSK------------------------------------------------------------------------------------------------------LLRWTTNKKHHVLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTV----------------------------EKKGNISSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN-------------------------AKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------RPEVVLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPIG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-----------------------EDTVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2E9-1", "uniprot_id": "Q9W2E9_DROME", "id": "Q9W2E9-1", "name": "Kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVYFLGDWGMGDSDLSS-----YQQHVPNIQQPRRIHGHDLLLQQQQQQLPQQQQQQQQQQQQQQQEFVAQIS---SSLSQVQAQLQFASGSSFLQQGSSPSPSQQQHG---------------------PVSSSSLVTANLQQLSVSSSNASSSSSNNNSASGCNTPTKPQKQK------------------------------------------------------------------------------------------------PLLLPEAAASTATAVGKSSKNPQLSKDLLDNEDEVALHPLSNQVGGHTRLLLLNQST----------------------------VIKPLNLRELDFYQNIPQDILKFVPKYKGVMQATTMGGAKLDKRYSPSFRDDAAAVPVRKMSASKRKRDEVLRMKVHKNGQAAEVIK-----------SISQLDNTNKQYFLMLENITSQFRNPCILDLKMGTRQHGDDASAEKRSKQMAKCAASTSGSLGVRLCGMQTYLADLEQYAKRDKYWGRELNE-GGFKTALHDFFHNGYRLR--IRVIRKILQRLLQLRRVIEKQSSYRFYSCSLLIVYEGFEENPMAPPPSMSQDEWPEAPRSATVPGTVFDYHPENSIDEDDLEDDDEAGNEAGDELEAHDTDDDLHLVAADSGNASATNSSTGGDACNYDADASNDSNSLLNLATRRHLHKRGFAEAAARGVKQTASHNTTTDEEEEDEHPAMPPPRTCGVMAAKAAAAAAGLAGKGQGAFIPISEETVFLDPEPALPSVTTSSPHSGDSWMNYSSNSSDDFSGLSEQIKAVASGRQTCNNSSDDASSDYESSIIGPTEAMFKRYKSQQSFDAATAADSASSPPLTAGNSSVSNGGTTVRSLVSPASSSASSLKSVKGAVKRLRCNDDDQQSASLGESDLREAKKSTITSTPVSAVSSPAKAAPQLRSCESISNQQSLLSGLLLDNNNEQRRNALLQQSSKSLDMSAPPTDDNQCFVDVRLIDFAHTAFVPRNGTMLP----------------TPAAAPVHHGPDGGFLTGLDSLNRLLNEIVAEERA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12494-1", "uniprot_id": "KCS1_YEAST", "id": "Q12494-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKKLSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGLQVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSHQPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADSGYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNRSNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTNRVGGHTAIFRFSKRAVCKALVNR-------ENRWYENIELCHKELLQFMPRYIGVLNVRQHFQSKDDFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQVLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPNDSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNSNTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNLQDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDGEFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSHHDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRAKCLKTTSRRLGVRICGLKVWNKD--YYITRDKYFGRRVKVGWQFARVLARFLYDGKTIESLIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDANKS----------------------------------NSKRKKAANVKVN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIDFARCVTKEDAMECMDKFRIPPKSPNIEDKGFLRG------------------------------------------------------------------------------------------------------------------------------VKSLRFYLLLIWNYLTSDMPLIFDEVEMNDMISEEADSNSFTSATGSKINFNSKWDWLDEFDKEDEEMYNDPNSKLRQKWRKYELIFDAEPRYNDDAQVSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:: ** ::: . : : : ::.: : : . .. : : . . . : . : .: : .: . *::**::. . ** *********:* **. * : ** :** :***:**::.: . :** ** :. * .* ::::* :. : :: :* * : .**:*..*:*::*:* ::.: *: :.. : . :. . ", "identical_positions": 46, "similar_positions": 88, "identity": "3.31%" }, { "cls_id": "homologset.agr.SGD:S000002425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UN02-1", "uniprot_id": "LCLT1_MOUSE", "id": "Q3UN02-1", "name": "Lysocardiolipin acyltransferase 1", "aln": "--------------------------------------MVSWKGIYFILFLFAGSFFGSIFMLGP-----ILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAF-------------VPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIH--------------------EPLQLLIFPEGTDLTENNKARSNDFAEKNGLQ--KYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYP-------YNIP-QTEKHLLLGDFPKEIHFHVQRYPADSLPT-SKEDLQLWCHRRWEEKEERLRSFYQGE--------------KNFHFTGQSTVPP-CKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWP7-1", "uniprot_id": "LCLT1_HUMAN", "id": "Q6UWP7-1", "name": "Lysocardiolipin acyltransferase 1", "aln": "MHSRGREIVVLLNPWSINEAVSSYCTYFIKQDSKSFGIMVSWKGIYFILTLFWGSFFGSIFMLSP-----FLPLMFVNPSWYRWINNRLVATWLTLPVALLETMFGVKVIITGDAF-------------VPGERSVIIMNHRTRMDWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIH--------------------EPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQ--KYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYP-------HNIP-QSEKHLLQGDFPREIHFHVHRYPIDTLPT-SKEDLQLWCHKRWEEKEERLRSFYQGE--------------KNFYFTGQSVIPP-CKSELRVLVVKLLSILYWTLFSPAMCLLIYLYSLVKWYFIITIVIFVLQERIFGGLEIIELACYRLLHKQPHLNSKKNE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYV8-1", "uniprot_id": "LCLT1_DANRE", "id": "Q6NYV8-1", "name": "Lysocardiolipin acyltransferase 1", "aln": "--------------------------------------MVSPRGVCFLLFLLLGSVFGSVFMLGP-----LLPLMLLSPSRYRWITDRIVATWLTLPVALLELVLGVKVVVTGDGF-------------IPGERSVIIMNHRTRLDWMFLWCCLLRYSYLRQEKICLKAALKSVPGFGWAMQVASFIFIQRRWEDDRTHMSNMLQYFCRIR--------------------EPVQLLLFPEGTDLTENTRARSDEFAEKNGLQ--KYEYVLHPRTTGFTFIVDTLRGGDNLDAVHDITVAYP-------QNIP-QTERHLLAGVFPREIHFHVQRFTVASVPA-GAAGLQAWCQERWREKERRLQRFYETVPRRFDAPAVGVCVREPCCQSGQCVCVPRCKSEGRVRIILVASLLYWSVFITAACASLCLCPPAQFYFLFMVVFFLCQQRFTGGLELMELACHRYWSRR---SADKQE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D517-1", "uniprot_id": "PLCC_MOUSE", "id": "Q9D517-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "aln": "-----------------------------------MGLLAYLKTQFVVHLLIGFVFVVSGLIINF-TQLCTLALWPISKHLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQA---------TVDHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLADYP--------------------EYMWFLLYCEGTRFTETKHRISMEVAASKGLP--PLKYHLLPRTKGFTTAVQCLRG--TVAAIYDVTLNFR-------GNK--NPSLLGILYGKKYEADMCVRRFPLEDIPA-DETSAAQWLHKLYQEKDALQEMYKQKG--------------VFP---GEQFKPAR-------RPWTLLNFLCWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V648-1", "uniprot_id": "G3V648_RAT", "id": "G3V648-1", "name": "", "aln": "-----------------------------------MGLLAYLKTQFVVHLLIGFVFVVSGLIINF-TQLCTLALWPISKNLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQA---------TVNHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLANYP--------------------EYMWFLLYCEGTRFTETKHRVSMEVAASKGLP--PLKYHLLPRTKGFTTAVQCLRG--TVAAIYDVTLNFR-------GNK--NPSLLGILYGKKYEADMCVRRFPLEDIPA-DETGAAQWLHKLYQEKDALQEMYKQSG--------------VFP---GEQIKPAR-------RPWTLLNFLCWATFLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRZ7-1", "uniprot_id": "PLCC_HUMAN", "id": "Q9NRZ7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "aln": "-----------------------------------MGLLAFLKTQFVLHLLVGFVFVVSGLVINF-VQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQA---------TVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYP--------------------EYMWFLLYCEGTRFTETKHRVSMEVAAAKGLP--VLKYHLLPRTKGFTTAVKCLRG--TVAAVYDVTLNFR-------GNK--NPSLLGILYGKKYEADMCVRRFPLEDIPL-DEKEAAQWLHKLYQEKDALQEIYNQKG--------------MFP---GEQFKPAR-------RPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4X7-1", "uniprot_id": "PLCD_MOUSE", "id": "Q8K4X7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase delta", "aln": "-----------------------------------MDLIGLLKSQFLCHLVFCYVFIASGLIVNA-IQLCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTIYTDPK---------ACPHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGWMWYFVEMIFCTRKWEQDRQTVAKSLLHLRDYP--------------------EKYLFLIHCEGTRFTEKKHQISMQVAQAKGLP--SLKHHLLPRTKGFAITVKCLRD--VVPAVYDCTLNFR-------NNE--NPTLLGVLNGKKYHADCYVRRIPMEDIPE-DEDKCSAWLHKLYQEKDAFQEEYYRTG--------------VFP---ETPWVPPR-------RPWSLVNWLFWASLLLYPFFQFLVSMVSSGSSVTLASLVLIFCMASMGVRWMIGVTEIDKGSAYGNIDNKRKQTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924S1-1", "uniprot_id": "PLCD_RAT", "id": "Q924S1-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase delta", "aln": "-----------------------------------MDLIGLLKSQFLCHLVFCYVFIASGLIVNA-IQLCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTIYTDPK---------ASPHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGWMWYFVEMIFCTRKWEQDRQTVAKSLLHLRDYP--------------------EKYLFLIHCEGTRFTEKKHQISMQVAQAKGLP--SLKHHLLPRTKGFAITVKCLRD--VVPAVYDCTLNFR-------NNE--NPTLLGVLNGKKYHADCYVRRIPMEDIPE-DEDKCSAWLHKLYQEKDAFQEEYYRTG--------------VFP---ETPWVPPR-------RPWSLVNWLFWASLLLYPFFQFLVSMVSSGSSVTLASLVLIFCMASMGVRWMIGVTEIDKGSAYGNIDNKRKQTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRZ5-1", "uniprot_id": "PLCD_HUMAN", "id": "Q9NRZ5-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase delta", "aln": "-----------------------------------MDLAGLLKSQFLCHLVFCYVFIASGLIINT-IQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPR---------AYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYP--------------------EKYFFLIHCEGTRFTEKKHEISMQVARAKGLP--RLKHHLLPRTKGFAITVRSLRN--VVSAVYDCTLNFR-------NNE--NPTLLGVLNGKKYHADLYVRRIPLEDIPE-DDDECSAWLHKLYQEKDAFQEEYYRTG--------------TFP---ETPMVPPR-------RPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PN43-1", "uniprot_id": "A0A8M1PN43_DANRE", "id": "A0A8M1PN43-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase delta", "aln": "--------------------------------MIRMGLLKVLKTQLLCHLIICYVFLVSGIIINL-LQLCTLPLWPINKQLARKINCRLGYSIASQLVALLEWWSGTECTLYTDPE---------SFRLYGKENAIVVLNHNFEIDFMTGWTFCERFGVLGSSKVLAKKELSFVPVIGWMWYFLEIVFCKRKWEEDRKTVVQSLRNLQDYP--------------------EFFWFLLHCEGTRFTEKKHKISMEVAEKKGLP--KLKYHLLPRTKGFCVTVQNLRG--KVTAVYDSTLNFR-------NNE--MPTLLGVLNGKKYHADLYVRRIPLDSIPE-DESECAAWLHKLYQEKDEFQEHYRQTG--------------RFP---GPITNPPR-------RLWALVNWLFWVCVLVYPICVLLLQLLLSGSTFTIVCTFVFCLAVSAGVRWMIGQTEIDKGSNYGVKDVQMNNN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV49-1", "uniprot_id": "Q9VV49_DROME", "id": "Q9VV49-1", "name": "", "aln": "--------------------------------------MSHLRG--LGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYIDPQD--------EQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYP--------------------DPVWLLLNAEGTRFTPAKHELSVKFAEERGLP--LLKHHLIPRTKGFTTSLPTMRG--ICPAIYDINLAFK-------KNAEPKPTMLSQLNGEPVEPYMYIRRVPLDVVPD-DEKEAAAWMQDFFAEKDKIIDSFHETG--------------SFFKNSGVKEVPEKIYKP---RLSTLLNFLGWATFAVLCILHYLVTSLVAGNWFGFITVLSILGGFYSLMEYAVNASKISKASAYGAAAAKK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12185-1", "uniprot_id": "YD018_YEAST", "id": "Q12185-1", "name": "Uncharacterized acyltransferase YDR018C", "aln": "-----------------------MKHSQKYRRYGIYEKTGNPFIKGLQRLLIACLFISGSLSIVV-FQICLQVLLPWSKIRFQNGINQSKKAFIVLLCMILNMVAPSSLNVTFETSRPLKNSSNAKPCFRFKDRAIIIANHQMYADWIYLWWLSFVSNLGGNVYIILKKALQYIPLLGFGMRNFKFIFLSRNWQKDEKALTNSLVSMDLNARCKGPLTNYKSCYSKTNESIAAYNLIMFPEGTNLSLKTREKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAP--SLDAIYDVTIGYSPALRTEYVGTKFTLKKIFLMGVYPEKVDFYIREFRVNEIPLQDDEVFFNWLLGVWKEKDQLLEDYYNTG--------------------------------------------QFKSNAKNDNQSIVVTTQTTG--FQHETLTPRILSYYGFFAFLILVFVMKKNH-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .. : : : . : : : : : :. ::: ** *:: * . * * :* :*: :* *.::.*. . : . ::: *** :: .: * .. * .: * *::.*: : : *::* .: : . . ::. :* . * : **: : . : : . . ", "identical_positions": 25, "similar_positions": 71, "identity": "5.2%" }, { "cls_id": "homologset.agr.SGD:S000002426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFA2-1", "uniprot_id": "GCST_MOUSE", "id": "Q8CFA2-1", "name": "Aminomethyltransferase, mitochondrial", "aln": "MHRIVSVVAPLGFRLQAQPLVQSRPLSSVQDVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRD-SHVDSHLHTRRHCSLFDVSHMLQTKIFGCDRVKLLESVVVGDIAELRPNQGTLSLFTNEAGGILDDLIVSNTSE-GHLYVVSNAGCRDKDLALMQDKVKEFQNRGLDVGLEVV---ENALLALQGPTATQVLQAGVT-----DDMKKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPATGAVHLATTLLKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRIAMD----FPGAKIIVPQLKGEVQ-RRRVGLICEG---APVRAHSPILNT-EGTVIGTVTSGCPSPSLK-KNVAMGYVPFKYSRPGTQLLVEVRRKQQMTVVSKMPFVPTNYYTLK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A0K6-1", "uniprot_id": "A0A8I6A0K6_RAT", "id": "A0A8I6A0K6-1", "name": "Aminomethyltransferase", "aln": "MQRTVRVVAPLGFRLQAQPLVQSRPFSSVQDGLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRD-SHVDSHLHTRRHCSLFDVSHMLQTKIFGCDRVRLMENIVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSE-GHLYVVSNAGCRDKDLALMQDKVKEFQNRGLDVGLEVV---DNALLALQGPTAAQVLQAGVT-----DDMRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPAAGAVHLATALLKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRVAMD----FPGAKIIIPQLKGEVQ-RRRVGLICEG---APMRAHSPILNT-EGAVIGTVTSGCPSPSLK-KNVAMGYVAFKYSRPGTQLLVEVRRKQQMTVVSKMPFVPTKYYTLK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48728-1", "uniprot_id": "GCST_HUMAN", "id": "P48728-1", "name": "Aminomethyltransferase, mitochondrial", "aln": "MQRAVSVVARLGFRLQAFPPALCRPLSCAQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRD-SHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSE-GHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVL---DNALLALQGPTAAQVLQAGVA-----DDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMD----FPGAKVIVPQLKGRVQ-RRRVGLMCEG---APMRAHSPILNM-EGTKIGTVTSGCPSPSLK-KNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTNYYTLK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKR4-1", "uniprot_id": "Q9VKR4_DROME", "id": "Q9VKR4-1", "name": "Aminomethyltransferase", "aln": "-------MFRLSYRLPAA-LGGLRHASSAAGEGQRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHTRQVGSIFDVSHMLQSRIFGKDAAACLESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSE-KELYVVSNAAMKEQDMGIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTG---KASLDQLYFMSSFVTTLAGIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESGVLKLAGLGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRD----FPGADVILGQLKEGVS-RRRVGLQMLGTKPPPARSGVAIFS--QGQQVGQVTSGCPSPSAG-RNIAMGYVAENLKAPGTKVEFKVRDKLYEAEVTKMPFVKANYYNRPKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48015-1", "uniprot_id": "GCST_YEAST", "id": "P48015-1", "name": "Aminomethyltransferase, mitochondrial", "aln": "----MSIIKKIVFKRFNS-------------TLKKTALHDLHVSLGGTMVPYAGYSMPVLYKGQTHIESHNWTRTNAGLFDVSHMLQSKLSGPHSVKFLQRVTPTDFNALPVGSGTLSVLLNPQGGVVDDTIITKENDDNEFYIVTNAGCAERDTEFFHDELQNGST--LDCQWKIIE--GRSLLALQGPKAKDVLEPLLSKTAPGKDLKELFFGQRHEFALKDGSLVQIARGGYTGEDGFEISIANEKAVEFAEQLLANPVMKPIGLAARDSLRLEAGMCLYGHELDESITPVEAALNWVISKSRRDLVDQKYWFNGYAKIMDQLNNKTYSKVRVGFKYLK-KGPAARNGVKIFLPDAETEVGLVTSGSASPTLNNINIGQAYVQKGYHKKGTKLLVQVRNKFYPIELAKMPLVPTHYYKQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: ::*.*:*:*: **.:* :.*:::** * . : ** ** .:********::: * . . :: : *: ..*:*::: * **::** *:.: .: .:*:*:**. ::* ::: : : .. * :.: .:*:*:*** . . *. :: .: :* * : . . :::* *******.***:. * .:: :* . :* **.**********:**** ::*. ****.:* * : * ** * * * *: **: . : ***: .. * *: :* ****..**: *:. .** ** : .:** * ::***:* ::**. ", "identical_positions": 119, "similar_positions": 119, "identity": "28.0%" }, { "cls_id": "homologset.agr.SGD:S000002427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PM9-1", "uniprot_id": "UCK2_MOUSE", "id": "Q99PM9-1", "name": "Uridine-cytidine kinase 2", "aln": "-------------------MAGDSEQTLQNHQQ---PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGLSKRQTNGYLN--------------GYTPS------RKRQASESSSRPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYG8-1", "uniprot_id": "UCK2_RAT", "id": "Q9QYG8-1", "name": "Uridine-cytidine kinase 2", "aln": "-------------------MAGDSEQTLQNHQQ---PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGLSKRQTNGYLN--------------GYTPS------RKRQASESSSRPH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZX2-1", "uniprot_id": "UCK2_HUMAN", "id": "Q9BZX2-1", "name": "Uridine-cytidine kinase 2", "aln": "-------------------MAGDSEQTLQNHQQ---PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNGCLN--------------GYTPS------RKRQASESSSRPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYM0-1", "uniprot_id": "UCK2A_DANRE", "id": "Q7SYM0-1", "name": "Uridine-cytidine kinase 2-A", "aln": "-------------------MAGDSDSKLDNHAEN-EHVDWQPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQKAKALKGQFNFDHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRKEE-TVTVYPADVVLFEGILMFYSQEIRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDFLNGGLTKR-LNGCLN--------------GHTP-------RKRHPSESSSRPH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZV79-1", "uniprot_id": "UCK2B_DANRE", "id": "Q7ZV79-1", "name": "Uridine-cytidine kinase 2-B", "aln": "-------------------MAGDSETHLKDRAEN-GHAVRQPFLIGVSGGTASGKSSVCEKIMELLGQNKIDRHQRQVVILSQDSFYRELTPEQKAKAVKGQFNFDHPDAFDSELIMKTLRDIIQGKTVHIPVYDFVTHSRKDE-FLTLYPADVVLFEGILMFYSQEIRDLFKMKLFVDTDPDTRLSRRVLRDISERGRELEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGFTKR-QNGFQN--------------GHGTP------RQRRTSESS-RPH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52623-1", "uniprot_id": "UCK1_MOUSE", "id": "P52623-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MASAGGGGSESAAPEADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHSRLPE-TTVVYPADVVLFEGILVFYTQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQ-RGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDLCKRHRGGPN----GRNHKRTFPEPGDHPGVLAT--GKRSHLESSSRPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EXY3-1", "uniprot_id": "F7EXY3_RAT", "id": "F7EXY3-1", "name": "Uridine-cytidine kinase", "aln": "MKVLAGAGRVGGCMSAAPEMASAGGGGSESAAPEADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHSRLPE-TTVVYPADVVLFEGILVFYTQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQ-RGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDLCKRHRGGPN----GRNYKRTFPEPGDHPGVLAT--GKRSHLESSSRPH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HA47-1", "uniprot_id": "UCK1_HUMAN", "id": "Q9HA47-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPE-TTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVR-RGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSN----GRSYKRTFSEPGDHPGMLTS--GKRSHLESSSRPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I71-1", "uniprot_id": "UCK1_DANRE", "id": "Q66I71-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MNSSG------LLCDNERPRHRPFLIGVSGGTASGKSTVCAKIMELLGQNKVDHHQRKVTIVSQDSFYRVLTPEQKAKALKGQYNFDHPDAFDTEFMCQTLKDIVEGKVVEVPTYDFVTHSRLPE-KICVYPADVVLFEGILVFYTQEVRDMFHMKQFVDTDSDVRLSRRVLRDMN-RGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWQRGSVNGHNHGRSLKRGVAEHGENPSGSSSNLTKRPLLEPSTRPH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC99-1", "uniprot_id": "UCK_DROME", "id": "Q9VC99-1", "name": "Uridine-cytidine kinase", "aln": "---------------MQDLRNADTLRLPNGDGAAANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNTVAIDLIVHHIGEILATTNSAQHSN-----------------------------TVRVAASSMKRDH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12084-1", "uniprot_id": "DAS2_YEAST", "id": "Q12084-1", "name": "Putative uridine kinase DAS2", "aln": "--------------------------------MDRKAVEEKRIVISIGGGHATGVGAIALDLQN-----------------TFKSLYNSIN--IRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDP-------IDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPS-TNENLGRAVLVDGIVKAIEDTKSQIEGNNTNN---------------KIRPRLWDFEAETMDLEKDRYYDLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.:.** *:* .::. .: : : . :*. :. :. .. : : . : : .: :: : . . * :. *:::. * :* .:.:: ::: *:*:*.* ** : :. ..:* ::.:* .::* :::: **:.:**:*** .:: :. ::*. * . : . . . ", "identical_positions": 28, "similar_positions": 87, "identity": "9.15%" }, { "cls_id": "homologset.agr.SGD:S000002428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0N4SVP8-1", "uniprot_id": "A0A0N4SVP8_MOUSE", "id": "A0A0N4SVP8-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MATTARMATSVSARKRLLKEEGMTKVEFETSEEVDRTLTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLPTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PV04-1", "uniprot_id": "E9PV04_MOUSE", "id": "E9PV04-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNR--GFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B8Q2-1", "uniprot_id": "IF4A3_RAT", "id": "Q3B8Q2-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MAATATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VC3-1", "uniprot_id": "IF4A3_MOUSE", "id": "Q91VC3-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MAANATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSVSVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38919-1", "uniprot_id": "IF4A3_HUMAN", "id": "P38919-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVA6-1", "uniprot_id": "IF4A3_DANRE", "id": "Q7ZVA6-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "MAT-----AVVPVRKRILKEEDMTKIEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFCVSVLQCLDIQVRETQALILAPTRELAGQIQKVLLALGDYMNVQCHACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVCLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVSQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHS8-1", "uniprot_id": "IF4A3_DROME", "id": "Q9VHS8-1", "name": "Eukaryotic initiation factor 4A-III", "aln": "------------MARKNAQAEDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDIRKLD-YGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNK--GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADLI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12099-1", "uniprot_id": "FAL1_YEAST", "id": "Q12099-1", "name": "ATP-dependent RNA helicase FAL1", "aln": "--------------MSFDREEDQ-KLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFEAPSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRELASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQMLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKKKVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMPANFAELS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :::*:**:.:. **::*.*:::******:**** **:**.*:*. *:.*:*****:********** :.:**.:* :: *.* *:****** ** : : *** ***:... **..: :*::*:: :* : *:******:***::: * ** ::*********:*.. ***:****:: ** ** ::***: ::***:* ***..*::*******::******:.* *::**********:**:*****.**** **:*****:::: ::**:* ****** *:**:.:*::**:* *****:*******:** ****:******: * **********:*********:.. *: **:**::** :*: ** *.*:* ", "identical_positions": 226, "similar_positions": 114, "identity": "54.59%" }, { "cls_id": "homologset.agr.SGD:S000002430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P799-1", "uniprot_id": "SYSC_RAT", "id": "Q6P799-1", "name": "Serine--tRNA ligase, cytoplasmic", "aln": "MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGED-ESIPEDVLN-FDDLTADTLAALKVSQIKKVRLLVDEAIQKCDGERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGD---------CTVRKK---YSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDSSYDEKYLIATSEQPIAALHRDEWLR--PEDLPIKYAGFSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLREFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKK---AKEVTLENQLQNMEVTEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26638-1", "uniprot_id": "SYSC_MOUSE", "id": "P26638-1", "name": "Serine--tRNA ligase, cytoplasmic", "aln": "MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEAVGDD-ESVPENVLN-FDDLTADALAALKVSQIKKVRLLIDEAIQKCDGERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGD---------CTVRKK---YSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGPLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLR--PEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMIATAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQAEKGIAVPEKLREFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKK---AKEVPLENQLQSMEVTEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49591-1", "uniprot_id": "SYSC_HUMAN", "id": "P49591-1", "name": "Serine--tRNA ligase, cytoplasmic", "aln": "MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDD-ESVPENVLS-FDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGD---------CTVRKK---YSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLR--PEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAA-ARDVTLENRLQNMEVTDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRC0-1", "uniprot_id": "SYSC_DANRE", "id": "Q6DRC0-1", "name": "Serine--tRNA ligase, cytoplasmic", "aln": "MVLDLDLFRTDKGGDPEIIRETQRKRFKDVSLVDKLVQADTEWRKCRFTADNLNKAKNLCSKSIGEKMKKKEPVGDD-DTLPEEAQN-LEALTAETLSPLTVTQIKKVRVLVDEAVQKTDSDRLKLEAERFEYLREIGNLLHPSVPISNDEDADNKVERTWGD---------CTVQKK---YSHVDLVVMVDGYEGEKGAIVAGSRGYFLKGPLVFLEQALINYALRILYSKNYNLLYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNTVDEKYLIATSEQPIAAFLRDEWLK--PEELPIRYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYASPHDGKSWEMFDEMIGTAESFYQTLGIPYRIVNIVSGALNHAASKKLDLEAWFPGSQAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKAEFVHMLNATMCATTRVICAILENFQTEEGIIVPEPLKAFMPPGLTEIIKFVKPAPIDQETTKKQKKQQEGGKKKKHQGGDADLENKVENMSVNDS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQL1-1", "uniprot_id": "Q9VQL1_DROME", "id": "Q9VQL1-1", "name": "serine--tRNA ligase", "aln": "MVLDLDLFRSDKGGNPDLVRENQKKRFKDVALVETVIAKDTEWRQCRHRADNLNKVKNVCSKVIGEKMKKKEPVGAMSEDLPADVTKDLTEIVAETLQPLTVNQIKQLRVLIDDAMTENQKSLELAEQTRNTSLREVGNHLHESVPVSNDED-ENRVERTFGD---------CEKRGK---YSHVDLIVMIDGMNAEKGAVVSGGRGYFLTGAAVFLEQALIQHALHLLYARDYVPLYTPFFMRKEVMQEVAQLSQFDEELYKVVGKGSEKAEEVGIDEKYLIATSEQPIAAYHRDEWLP--ESSLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFVLTSPHDNKSWEMMDEMIGNAEQFCQSLGIPYRVVNIVSGALNHAASKKLDLEAWFGGSGAYRELVSCSNCLDYQARRLLVRFGQTKKMNAAVDYVHMLNATMCAATRVICAILETHQTETGIKVPEPLKKYMPAKFQDEIPFVKPAPIDLELAAAEKQKGKKEKTK----KDPAAG-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07284-1", "uniprot_id": "SYSC_YEAST", "id": "P07284-1", "name": "Serine--tRNA ligase, cytoplasmic", "aln": "-MLDINQFIEDKGGNPELIRQSQKARNASVEIVDEIISDYKDWVKTRFELDELNKKFNKLQKDIGLKFKNKE--------------------DASGLLAEKEKLTQQKKELTEKEQQE--------DKDLKKKVFQVGNIVHPSVVVSNDEE-NNELVRTWKPEDLEAVGPIASVTGKPASLSHHEILLRLDGYDPDRGVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELMSKTAQLSEFDEELYKVID---------GEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSSCFRREAGSHGKDAWGVFRVHAFEKIEQFVITEPE--KSWEEFEKMISYSEEFYKSLKLPYRIVGIVSGELNNAAAKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGDREKKYVHCLNSTLAATQRALCCILENYQTEDGLVVPEVLRKYIP-GEPEFLPFVNELPKNSTSSKDKKKKN---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:: * ****:* ::*:.*. * . :*: :: .:* : *. *:*** * .* ** *:*:** *. * . . :: : * :. : : : ::** :* ** :****: :*.: * : . * ** :::: :** : ::*. :.* ****: . ***:****::.*: * ::.* : :*.:*.**:*.:.****:********:. *************:* .**: ..***:*.* *:***:*.****:*: *:**** ***:**** :.*. **** :::** :*.* ::* :**::*.**** **:**:** ****** . ::******** ***:*.* :* * .* .:** **:*:.*: *.:*.***..*:* *: *** *: ::* : : **: * : : :*:: ", "identical_positions": 189, "similar_positions": 137, "identity": "35.59%" }, { "cls_id": "homologset.agr.SGD:S000002432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62281-1", "uniprot_id": "RS11_MOUSE", "id": "P62281-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62282-1", "uniprot_id": "RS11_RAT", "id": "P62282-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62280-1", "uniprot_id": "RS11_HUMAN", "id": "P62280-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZYK5-1", "uniprot_id": "D3ZYK5_RAT", "id": "D3ZYK5-1", "name": "", "aln": "---MADTHTERAYQNQPTISQNKKHVLLGE-TGKEKLPRYHKNIGLGFKTTKEASEGTYIDKKCPFPGNVSIQGRMLFVVVKKMKLQRTVAIRQDCLHYIRKYNRFEKQPKNTPVRLSPCFRVVQINDIVTVGECRPLSKTVFYSMCKVTTAAG-TRKQFQKF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QE68-1", "uniprot_id": "A0A8M9QE68_DANRE", "id": "A0A8M9QE68-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MAVTQNVRDYQKQPTIFQNKKGVLAVEGSGKEKLPRYHRNVGLGFKNPREAIDGTYIDKKCPFTGNVSIRGWILSGVVTKMKMQRTIVIRRDNLHYIRKYNRFEKRHKNMSVHLSPCFRDVTVGDIVTVGEWQTLSKTVRFNVLKVTKAEA-VPEVLELLFLQYGSPVLLKKKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9B6-1", "uniprot_id": "RS11_DROME", "id": "Q0E9B6-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MAD-QNERAFQKQFGVNLNRKVKPGIT---KKKLLRRSRDVGLGFKTPREAIDGTYIDKKCPWTGDVRIRGRILTGVVRKAKMQRTIVIRRDYLHFVRKYSRFEKRHRNMSVHCSPVFRDVEHGDIVTIGECRPLSKTVRFNVLKVSKGQG-AKKSFKKY--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX47-1", "uniprot_id": "RS11A_YEAST", "id": "P0CX47-1", "name": "Small ribosomal subunit protein uS17A", "aln": "MSTELTVQSERAFQKQPHIFNNPKVKTSKR------TKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFR-VQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :*:* : * * * :: *****..: * :*:*******:.* * *:* :* .* . *::**:.**: **:: **.*:**: :* .*: ** ** * .****:*: :.:**** :.: **: . . . : : ", "identical_positions": 56, "similar_positions": 46, "identity": "31.64%" }, { "cls_id": "homologset.agr.SGD:S000002433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CE22-1", "uniprot_id": "DMTF1_MOUSE", "id": "Q8CE22-1", "name": "Cyclin-D-binding Myb-like transcription factor 1", "aln": "---------------------------------MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQND-------PDEVDSEDSTEPPHKRLCLSSED-DQSIDDATPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDS------------LTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMS--------------KDERKDFYRTIAWGLNR------------------PLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVAD--ENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCN-SSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTNPTVTLAAAA-PASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSLSQEELTVDSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPSDLASAYVTEDL-ESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEASNIIGSSLGSPVSEDSKDVEDLVNCH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG1-1", "uniprot_id": "DMTF1_RAT", "id": "Q66HG1-1", "name": "Cyclin-D-binding Myb-like transcription factor 1", "aln": "---------------------------------MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQND-------PDEIDSEDSTEPPHKRLCLSSED-DQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEMSPLGTEEVSAVSQAWFTTKEDKDS------------LTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMS--------------KDERKDFYRTIAWGLNR------------------PLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVAD--ENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCN-SSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAA-PASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTADSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKYSDQNSTELMNSVMVRTEEEIADTDLKQE-PPSDLASAYVTEDL-ESPTIVHQVHQTIDDETILIVPSPHGFIQASDGIDAESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y222-1", "uniprot_id": "DMTF1_HUMAN", "id": "Q9Y222-1", "name": "Cyclin-D-binding Myb-like transcription factor 1", "aln": "---------------------------------MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNE-------ADEIDSEDSIEPPHKRLCLSSED-DQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDS------------LTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMS--------------KDERKDFYRTIAWGLNR------------------PLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVAD--ENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTN-SSVQHVQIRVARLEDNTAISSSPMAALQIPVQITHVSSADSPAT-VDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAA-PASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGL-ESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG03-1", "uniprot_id": "DMTF1_DANRE", "id": "Q6DG03-1", "name": "Cyclin-D-binding Myb-like transcription factor 1", "aln": "---------------------------------MNTG-DVPATVTLESVNSVTFTQDTDGNIILHCPQND-------GEDLGSDETTEPVHKRIRLSSEDGEDPQDSASTEYSVVTLPITDGDESFEVTMTAT-EMRDEELESDDLS-----ETTGKDSSAQKKGEDVSAVSQAWFTTKEDKDT------------LVNKGHKWKQGMWSKEEIDLLMTNIELYLKNRGIQDPAEIIFEMS--------------KEERKDFYRSIACGLNR------------------PLFAVYRRVLRMYDNRNHVGKYTDEEINKLKELRQKHGNDWATIGSALGRSASSVKDRCRLMKDTCNTGKWTEEEERRLAEVVHELTGTEAGDVVTQGVSWASVAELVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDDINLVRRIAELEVED--ENEINWDILASGWSSVRSPQWLRSKWWTIKRQVANHKELPFPVLLKGLQDVVEAP---PSTMNKVVVVGSRSANASPSPVTALQI-----------------PVQIPVQITHVSSSDGSSGTSDSETITLNSGALQTFELLPSFHLQPTGTPGTYFLQTGTNQSLPLTLSANPTVTLTAAASPSSPDQIILHSLT-----TDTENVTVQMSHPGIIIQTVTSEDLADPLGQSELEGE-----------------------------------------------------QVLVKEEPSENQTNPAIE-EPSEEQSKQGEKTL-DSSKVV---------ETVLMVPSPGSFIPTNEDISSDSVLPLGTLTDPILENQEEGSN-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0RCD4-1", "uniprot_id": "M0RCD4_RAT", "id": "M0RCD4-1", "name": "Cyclin-D-binding Myb-like transcription factor 1", "aln": "---------------------------------MSTCEEVSEEVAHQVVKSVFVIEDTSRNLIP-CLQNG-------ADER--ENHTEPLLKRPCLSPEV------DSTPCISAVAFPLQEIQQSFDLVTSTVTQMAGEEVAAASMMPFQIIQNVTPHEVFSLANVEQSIVSQTWFTGKEVKDA------------LANQGHKWKQGMWTKEETNILMSNIEQYMKEHGVENPAEIIFKMS--------------KGKRKDFYRSISFGLNR------------------PLFSIYRRVIRMYDDRNHVGKYSPEEIEKLKELWQKHGNDWITIGAAMGRSPSSVKDRWRLMKDACNAGKWTEEEEQILGDAVHELTGTEVDEKVTQGVCWATVAQQVGTRSAKQCRAKWLNYLNWKQTGGIEWTRKDEVTLILRLAELDVAD--ESEIRWDELAKGWESVRSPQWLRSKWWNIKRQITNHKDFAFPVLVRCLQQEYERQNASLRFWKNKSGSDMSESNPD------------------------ISVQQVSFGVTSIEDNN------TSICPVPMTGSQITLQLLP-----------------RSLTDLPAAVGDSESVTLPTGP------Q-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62187-1", "uniprot_id": "TTF1_MOUSE", "id": "Q62187-1", "name": "Transcription termination factor 1", "aln": "MKGGTSKFKTHTETLYKKKKWSSVSEKRPQKCPSQCLESKQPQVSVLGKRRRASQTPAQETLESEWPQKAKRKKRRREPQTPAQETLESEWPQKAKKKKRRGEPQTPTQESLESEQPPVSLLGKRRRESQTPAQENSESEQPRKAKRRRKKRKGSQQPTSSLLKTPETFLKAKKTTSAHKKKKNSVLEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVRETGELPAAKPQEHGCRELLGDVRSRKKQKHLQKVAPWDVVQGSQPESISLPPSEPLSSEDLEGKSTEAAVFCKKKSKKNVFRSQELEPIPDSLDDSETISERLDSTHHGGAVGAGEECESTKESHSIKKKSKKKK---HKSVALATSSDSASVTDSKAKNALVDSSEGSGAVREEDVDHRPAEAEAQACSTEKHREAMQRLEPTHEEESNSESASNSAARHISEDRRESDDSDVDLGSAVRQLREFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSAKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKTLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIGGTRNQGAWSKAETQRLIKAVEDVILKKMSPQELRELDSKLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVNALQAKITLIERLYELNVNDANEIDWEDLASAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYKNSLPLLKEKLDKKMKKKDGQIQTPAAPKQDFLFKDIFHCDDDSDEGSPEEPSASDVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12457-1", "uniprot_id": "NSI1_YEAST", "id": "Q12457-1", "name": "RNA polymerase I termination factor", "aln": "-----------------MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKKLKKQKKRKHG------SKMSHEDEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSMREKDKRSCHKKSSNSRSERKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPDD---------------LIAETAFDKYVDTEKAYLAKHPSKSLEVNEDDKENNFNNNSS----------------TLVRIYTDLEGIPND------------------GSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRSDIVKASVIDGAITKS---IGKKFTPSEENALDQFIEEYMKIRGLDRRQMCERIWSTDGVIRDGFWANISKVLPYR-TRSSIYKHIRRKYHIFEQRGKWTPEEDQELARLCLEKEGHWTEVGKLLGRMPEDCRDRWRN--YMKCGSKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRYNQMYSR--------------------------GPKGKRISDNPTFKDMINWTVVSERMSGTRSRIQCR---------------------YKWNKLVTDEAARSMLSIPVSE------------------------------------------------------------------------------------------------------------------RKWLLERLKQLPKTSYSNIDWNSIATYKPGYPRTG--------------LELRLCYEQMREKIHDFKGRSTAEIIDSLLEQIN---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .: :: :: : : . . . : .. . : . : . : : . . . . :: . : . :.. :* : . :..: . .. :: : : . . . * : . :. . : : * * . .. . . . : . . .. :: ..: . : : . . * :. . ", "identical_positions": 5, "similar_positions": 84, "identity": "0.58%" }, { "cls_id": "homologset.agr.SGD:S000002434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMK8-1", "uniprot_id": "VPS54_RAT", "id": "Q9JMK8-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKKEVDPTKHVR---------------------PVQSLPDVCPKEPT------------VTDQHRWTVYHSKVN---LPAALNDPTLAKRESDFFTKTWGLGFVDTEVIP-SLYLPQIS---KEHFIAYQQEISQREKIHERCKNI--------CPPKDTFDRTLLHIHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLKKTSQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVSNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGVHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEG-----ECQVLEEERLVSLVFGLLEQRKLNFLEIYGEETIITAKNIIKECVINKVAQVEEIDTDAVVKLADQMRMLNFPQWIDLLKDIFSKFTIFLQRVKATLNVIHSVVLSVLDKNQRTRELEEVSQQRSAGKDNSLDTEVAYLTHEGLFISDAFSEAEPASAAVDTTSQRNTSPHSEPCSSDSVSEPECTTDSSSSKEQTPASATLGGVDIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRAKDGFLEKLNSTEFIALSRLMETYIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSLLLDNERWKQADVPAEFQDLVDSIADGKIALPDKKPAATEDRKPADVLVVEGHQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPRKQWSLLRHFDHITKDYHDHIGEISSKLIAIMDSLFDKLLSRCEVEAPAPSPCFRNICKQMTKMHEAIFDLLPKEQTQMLILRINASYKFHLKKQLSHLNVINDGGPQSGFVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SPW0-1", "uniprot_id": "VPS54_MOUSE", "id": "Q5SPW0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKKEVDPTKHIR---------------------PVQSLPDVCPKEPTGDSHTLCVAPSLVTDQHRWTVYHSKVN---LPAALNDPTLAKRESDFFTKTWGLDFVDTEVIP-SLYLPQIS---KENFIAYQQEISQREKIHERCKNI--------CPPKDTFDRTLLHIHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGSRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLKKTTQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEG-----ECQVLEEERLVSLVFGLLKQRKLNFLEIYGEEMIITAKNIIKERVINKVSQIEEIDTDVVVKLADQMRMLNFPQWIDLLKDIFSKFTVFLQRVKATLNIIHSVVLSVLEKSQRTRELEEIPQQRSAGKDSSLDTDVAYLTHEGWFISDAFSEGEPASAAVDTTSQRNTSPHSEPCSSDSVSEPECTTDSSSSKEQTSACAPPGGIEIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRAKDGFLEKLNSTEFIALSRLMETFIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSLLLDNERWKQADVPAEFQDLVDSIADGKIALPEKKPVVTEERKPADVLVVEGHQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQWSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSPCFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Q0-1", "uniprot_id": "VPS54_HUMAN", "id": "Q9P1Q0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKIEVDPSKHIR---------------------PVPSLPDVCPKEPTGDSHSLYVAPSLVTDQHRWTVYHSKVN---LPAALNDPRLAKRESDFFTKTWGLDFVDTEVIP-SFYLPQIS---KEHFTVYQQEISQREKIHERCKNI--------CPPKDTFERTLLHTHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLRKTSQAVKMLRDKIAQIDKVMCEGSLHILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLED-----DCQVLEEERLISLVFGLLKQRKLNFLEIYGEKMVITAKNIIKQCVINKVSQTEEIDTDVVVKLADQMRMLNFPQWFDLLKDIFSKFTIFLQRVKATLNIIHSVVLSVLDKNQRTRELEEISQQKNAAKDNSLDTEVAYLIHEGMFISDAFGEGELTPIAVDTTSQRNASPNSEPCSSDSVSEPECTTDSSSSKEHTSSSAIPGGVDIMVSEDMKLTDSELGKLANNIQELLYSASDICHDRAVKFLMSRAKDGFLEKLNSMEFITLSRLMETFILDTEQICGRKSTSLLGALQSQAIKFVNRFHEERKTKLSLLLDNERWKQADVPAEFQDLVDSLSDGKIALPEKKSGATEERKPAEVLIVEGQQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLSDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQYSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSACFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC0-1", "uniprot_id": "VPS54_DROME", "id": "Q9VLC0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "------MATTRSAGGAATSVDTGPAAGNSGIRKLSTASVGGIAGGVAPSWQSCYYCTREHFKSISDFVNHLRNRHCTREGGSFVCRYGFNGVCASLPLDGVSDRDYDAHVAKYHVNQHTREMPPEWGVYSAAQN---LPAVLNDPSRGK-QSNLFTKKWGEHFVERSHVPPSPRLPDIT---HADFTVYLGSIGKRYRWHERRQQQ--------LERDKPLENGAQGAPGPGTGGQTPTHLSSVPEIFLKSQLQLHHPATFKQVFPN-YMQTSASSPESHQQTG---RQLQEQLSHYLDMVEVKIAQQVSQKSAAFFHAMTTQHAILAEMEQAADQVRQLRAALAELHSHSVVDSFKVLRFAQRRQHYNLTLDKLRLMATVHKTQPMLQLLLGTQDYVAALDLIGTTQEILSAELLGIHCFKHLPMQLSEMEKLIDKMLTTEFERYAAADLNRPLTDALRETDSVCAEEDKLVAIVMGLLRKQNFSFVQAYQQEAIATIRAIIKQLLIEVLARSDSDQEISLTGHGEQALELTLPEWIALLQRSSQALVSILERIKTVVGIMQQTADAAVG------------------------------------------------------------------AQDAVN--------------------------LIDSEAFLSPGHHEQLKNQLQQLLQAVCHYCHERCANIVSPQSLE--RSSASEQELFQLSEIVDHFGETTRSICGVASVPLQLALKVQASRYAQRFHSERKQKLSLLLDQERWRQVDIPHEFQRIIERMAAGDYAKPEMGNLISNGAGNPVLLVEGKQPYTLVSASLMLIRMLYEYGCSAHRLPLLASYHARNVVDLLRCFNSRSCQLIIGAGAMRVAGLKTITSTNLALVSRALQLVLWLLPKLKEHFQAMSG---------YETIERDYQGHIKEIENKIHGIVSERLAAQLDAWEARPPIPSQTFRHISRHLVKLHEAIAGVLPEAQIHEIYGVVHRNFKDKLREQLLKLNVNNNGGPQHGVVTSELTFYMETLRTLKALPAEQLDNGILEEIWLY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12071-1", "uniprot_id": "VPS54_YEAST", "id": "Q12071-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "MSISETPHNKSQGLQKAAGRPKIVVPEGSPSRN----------------------SDSGSFTIEGDTSLNDDLLSISG------------SVTPRARRSSRLSLDSITPRRSFDSRTLSVANSRSFGFENETHSGSMDFSPLGNNSIYEIVMNTRRKNWLNYPTVADIPQVSLSKNDLDDHWKTHVIEYVKNIKSDYQIFQSTNNIRNMNQMEQLKELREGENMHEESFEANLRQGDAELINSIPDFYFSDKFQLDNPRTFHKVLDAIDLFLTKLDMKRQAERDEAFSELRDRLNDFLDIVETLLVTEISKSSHKFFHALSEVDNIQKRALDTMSELKELAQNIKTIDAENIRKKISHLEMIFKRKNVEKLEQGLLQAKLVLNKTDECKSMYEENKLDNCLELIKSIDYLIKGDDS------------------INEDVQSWTRCWPYKLSNLRTIP------ALSATREFLTNMKIEIGGKFSLQLSILLIDDLRSFCKSIKPKETLHRIQTGSNDKKQTIFTDNFSSKITELIVRLNRCEELTSAFDLYREKSITELKSIIKIYLPTEN------------------------------------------------------------------AHADNN----------------------------HDEKHLNNGSTS--GSKLSRLIKEQTPAEFQSMLVNIFTHALEALRRLYGHQKLLLDISLNELASVKSPNENQHN---MITQLDIRTG--INEIIRIIQLRTGKIIAVRRELNLSLRYDYFLKFYAICVIFIQECEVLSGEFLTKYLSNVLASQIKHYANAQSSKNYRNIKKKIDAEEWIPYIVDSSIQSDVNDIVSSIDIDPLSWTT---ILDMVGGSHDCENGRSEDKEKDEGNETYQGHRKSVVVGDKTFVASSSLLATIEVIKELMVLSINLPSIYLSNFEKLCYDALQYYNSSAMASVTQPGNSLLKTGRNLSIMGESLDCLAEFVIIVQRFYQRLSNSNRDFEPFDASHYTTLLGQFQASSNKIYMANAPPPPV-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. . .. .* . *. * : . . : : . . : *.: : : *.* . . * :: : .. * .* . : .: :: :. :..:*.:::. .: *... **:.*: : : . . . . *:::*..:**:**. :. ::* * ****:: . : .: . :: * : :. .: *.: *:: : * * :. : : .. .*:** : : ::. : *:: : : :. * . .: * : : : : .:.: :. : * : :. : .. . : . : : : . : :: : : : . .. : . .: *. .::..*: .: : .:: : . ::: : : : . : *. :: :.: : : . :: .* : .: :: . :. : . :* : *: . : .: : : : : *:: :: . . : :.* . .. : .. : : . . : :: :: . ... *. : . . : : : . : * : . : ..:: ::. : . ::. :* . . ", "identical_positions": 50, "similar_positions": 262, "identity": "4.67%" }, { "cls_id": "homologset.agr.SGD:S000002437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7B8-1", "uniprot_id": "G3V7B8_RAT", "id": "G3V7B8-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLSFLSARQS--GLEDPLRLRRAQSTRRVLGLELNKDRDVERVHCS------------GVNTLDIEPVEGRYMLSGGSDGVIVLYDLENASRQP------------------------------------------------------------YYTCKAVCSVGRSHP-----------------------DVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAVESAN-------------TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN---SSSGDNTLVNYGKVCNSSRKGLKFTVSHGCNSEFVFVPYDSTIAMYAVYSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPASYEPVPDDDDEAPTKSRLNPAFTDAWSSSDEDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFD5-1", "uniprot_id": "ERCC8_MOUSE", "id": "Q8CFD5-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLSFLSARQS--GLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGS------------GVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQP------------------------------------------------------------HYTCKAVCSVGRSHP-----------------------DVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESAN-------------TAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWN---SSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13216-1", "uniprot_id": "ERCC8_HUMAN", "id": "Q13216-1", "name": "DNA excision repair protein ERCC-8", "aln": "MLGFLSARQT--GLEDPLRLRRAESTRRVLGLELNKDRDVERIHGG------------GINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQS------------------------------------------------------------YYTCKAVCSIGRDHP-----------------------DVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHR------QEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESAN-------------TAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWN---SSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDD-ETTTKSQLNPAFEDAWSSSDEEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12021-1", "uniprot_id": "RAD28_YEAST", "id": "Q12021-1", "name": "Radiation-sensitive protein 28", "aln": "MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSKQSNYSTKEKTPLSIGVNCLDIDDTG-QVLLGGGDDGSLSIWGLDESLHRNDEGEQELINKRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNKYRMYRQSSAAVPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDKTVKIWDTNRFEAVQDINLGYKINQIDNN-VVDDSSLLVVASEDYYPRLIDLRTMNSGVTALGMGNQTRMQSEILCCKFNPVREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRFKTINNDDNDDQSDVYFSSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEILQPEGLASYSQLGTQDLSRIKYKKRVSRR-----LLWFDKFLLCITDNGEVEIYNTEEKKLWNKLEYPMVNQVKKNQASHCQFSSMIVQT--NIMNSVGLKLFFGTNNNTVSDGGSIFECS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **. * .*:: * .. .*:* *.: :: . : . *:* ***: . : :*.**.** : ::.*::: :: : ..*. .: *.* . *:*.: *::** *.*** :.* ***:*:**** :::.: :*: .: . . . . . .*:.*.:.. :* **:: ... * .***. .:.* : *:* .. :. *****:* . *.:::.: . :. * .** ..: :.*:* .* ::* *.::.:*. . : *..*.:: ... . ::: . : ..: : . .** . . * : : * . : .*:: : : : :. . * :. *. * : . ", "identical_positions": 80, "similar_positions": 156, "identity": "15.5%" }, { "cls_id": "homologset.agr.SGD:S000002438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMY5-1", "uniprot_id": "B0BMY5_RAT", "id": "B0BMY5-1", "name": "", "aln": "-----MQAALEVTARYCSRELDQYGQCVAAKPESWHRDCHYLKMSIARCT-SSHPIIRQIRQACAVPFEAFEECLRLNE---AAVGNCAEHMRRFLQCAE-QVQPPSSPTTGEAQPLPAS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQP3-1", "uniprot_id": "CHCH5_MOUSE", "id": "Q9CQP3-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 5", "aln": "-----MQAALEVTARYCSRELDQYGQCVAAKPESWHRDCHHLKMSIARCT-SSHPIIRQIRQACAEPFEAFEKCLRLNE---AAVGNCAEHMRRFLQCAE-QVQPPSSPTTGEAQPLPAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSY4-1", "uniprot_id": "CHCH5_HUMAN", "id": "Q9BSY4-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 5", "aln": "-----MQAALEVTARYCGRELEQYGQCVAAKPESWQRDCHYLKMSIAQCT-SSHPIIRQIRQACAQPFEAFEECLRQNE---AAVGNCAEHMRRFLQCAE-QVQPPRSPATVEAQPLPAS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04341-1", "uniprot_id": "MIX14_YEAST", "id": "Q04341-1", "name": "Mitochondrial intermembrane space cysteine motif-containing protein MIX14", "aln": "MSDILDEIVIEDVVANCPQEFLQYHKCIRDN-EENPGKCKDGRMILSTCIREKVPSVKSIMSECSEPMKKYDQCIRDNMGTRTINENCLGFLQDLRKCAELQVKNKNIKPSINGVNLELIKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* .. * :*: ** :*: : *. .*: :* :: * .. * ::.* . *: *:: :::*:* * : ** .:: : :*** **: .: :. * ", "identical_positions": 25, "similar_positions": 40, "identity": "20.49%" }, { "cls_id": "homologset.agr.SGD:S000002443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE6-1", "uniprot_id": "HIBCH_RAT", "id": "Q5XIE6-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQQFVWRLQSRFSSIR--RASVILQHLRMSKHTETA-EVLLERRGCAGVITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAG-GKAFCAGGDIKALSEAKK-AGQTLSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQG------KLGYFLALTGFRLKGRDVHRAGIATHFVDSEKLHVLEEELLALKSPSAED-----VAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSAN------TVEQILENLRQ-----DGSPFAMEQIKVINKMSPTSLKITLRQLMEGSTKTLQEVLTMEYRLTQACMEGHD----FHEGVRAVLIDKDQTP------------------------------------------------------------KWKPADLKDVTDEDLNSYFKSL-GSRDLKF------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZS1-1", "uniprot_id": "HIBCH_MOUSE", "id": "Q8QZS1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQPYAWRLLSRVSSFR--RASVILQHLRMSMHTEAA-EVLLERRGCGGVITLNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLIIIKGAG-GKAFCAGGDIKALSEAKK-ARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQG------KLGYFLALTGYRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAED-----VAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSAN------TVEQIIENLRQ-----DGSPFAIEQMKVINKMSPTSLKITLRQLMEGSSKTLQEVLIMEYRITQACMEGHD----FHEGVRAVLIDKDQTP------------------------------------------------------------KWKPANLKDVTDEDLNSYFKSL-GSSDLKF------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NVY1-1", "uniprot_id": "HIBCH_HUMAN", "id": "Q6NVY1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQREMWRLMSRFNAFK--RTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-GKAFCAGGDIRVISEAEK-AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG------KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKEN-----IASVLENYHTESKIDRDKSFILEEHMDKINSCFSAN------TVEEIIENLQQ-----DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHD----FHEGVRAVLIDKDQSP------------------------------------------------------------KWKPADLKEVTEEDLNNHFKSL-GSSDLKF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EB4-1", "uniprot_id": "HIBCH_DANRE", "id": "Q58EB4-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MS-LIIFTSAQRLRSVC--RLQRIHGHMMSSK---AGSEVLFEKVGKAGVITLNRPKALNALTLNMIRHIYPQLKKWDKDSETDIVIIKGAG-EKAFCAGGDIRAIAEAGK-AGNLLSQVFFREEYILNNTIGTYQKPYVALINGITMGGGVGLSVHGQFRVATEKTLFAMPETGIGLFPDVGGGYFLPRLQG------KLGLFLALTGFRLKGRDVQRVGVATHFVQSEKIESLEKDLVDLKSPSISD-----VAQLLDSYQEQSHLDAEKPFVLQEQTEAIDRLFSAG------SVEEIVENLKK-----DGSAFALKQAETLAKMSPTSLKLTFRQIEEGARMSLQEVFMMEYRLSQACMNGHD----FYEGVRAVLIDKDQSP------------------------------------------------------------KWKPSTLAGVSEQFVDKCFSSL-DERDLKL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BP1-1", "uniprot_id": "Q86BP1_DROME", "id": "Q86BP1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "MQGPIQRLVYTFGHRTCSQLPMIGGATISQTKPTTMALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKS--KSLVIIKGTG-DKAFCAGGDVRALVEAGP-TDE--SKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG------KLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLN--CPDADD-----VPELLQKYHSP----PEKPFSLQPVLEQINKNFSAD------SVEGILENLQN-----DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSD----FKEGVRALLIDKDQKP------------------------------------------------------------QWQPTKLADVTEEHVQWFFRKLPDTEELKL------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28817-1", "uniprot_id": "HIBCH_YEAST", "id": "P28817-1", "name": "Small ribosomal subunit protein mS47", "aln": "--------MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQIALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKKEQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTNDDTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ** . :* ***** ***:. :* . :: *: :. . ::*:*.:. ::******: .: : :* :** * :.. * ::::.***********:* :*:*::. :**** **:*****. : ***: ::. :* *** : * *. *:*:*: .*.:: *: * * .: . :::. * :: : :: :. ::* *::**:: :*. :* : : . **:*:::::* : .: : . : : : * * *..: ****:: * : : *::. : * .: *: ", "identical_positions": 89, "similar_positions": 115, "identity": "17.52%" }, { "cls_id": "homologset.agr.SGD:S000002444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIM7-1", "uniprot_id": "SYK_RAT", "id": "Q5XIM7-1", "name": "Lysine--tRNA ligase", "aln": "MLMQAAVRLVRGSLRQTSWAEWG-QRELRLGQLAPFTTLRKDKPLSDRRSELKRRLKAEKKLAEKEAKQKELSEKQLNQTTAAAATNHTADN--GVGAEEETLDPNQYYKIRSQAVQQLKVS-GEDPYPHKFHVDISLTQFIQEYS-HLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTK-----KGELSIVPREMTLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVRSITGSYKITYHPDGPE-GQAYEIDFTPPFRRISMVEELEKVLGVKLPETSLFETEETRKILDDICVARAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRCKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKETATATETPESTEASPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MN1-1", "uniprot_id": "SYK_MOUSE", "id": "Q99MN1-1", "name": "Lysine--tRNA ligase", "aln": "----------MATLQESEVKVDG-EQKLSK-------------------NELKRRLKAEKKLAEKEAKQKELSEKQLNQT--ASAPNHTADN--GVGAEEETLDPNQYYKIRSQAVQQLKVT-GEDPYPHKFHVDISLTQFIQEYS-HLQPGDHLTDVTLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTK-----KGELSIIPQEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIVRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVKSITGSYKITYHPDGPE-GQAYEVDFTPPFRRISMVEELEKALGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFPAMKPEDKKETAATTETPESTEASPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15046-1", "uniprot_id": "SYK_HUMAN", "id": "Q15046-1", "name": "Lysine--tRNA ligase", "aln": "----------MAAVQAAEVKVDGSEPKLSK-------------------NELKRRLKAEKKVAEKEAKQKELSEKQLSQAT-AAATNHTTDN--GVGPEEESVDPNQYYKIRSQAIHQLKVN-GEDPYPHKFHVDISLTDFIQKYS-HLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTK-----KGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE-GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W327-1", "uniprot_id": "Q9W327_DROME", "id": "Q9W327-1", "name": "Lysine--tRNA ligase", "aln": "MFARCALRTVQGSWPR--CRYTGIQPLAAG----------------FHVSAPQMEPSKQTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTK-----KGELSVMPSEIKLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPE-GPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFPAMKPEDANRTAAETAPTAQQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15180-1", "uniprot_id": "SYKC_YEAST", "id": "P15180-1", "name": "Lysine--tRNA ligase, cytoplasmic", "aln": "----------MSQQDNVKAAAEGVANLHLD----------------------EATGEMVSKSELKKRIKQRQVEAKKAAKKAAAQPKPASKK---KTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYA-HLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGE-LEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFPTLKPDVLREEVKKEEEN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . .* *. : . : *: .: :: : :.*.:*:: ** :::*: . :********. * :*: :* *: *: * : .:.:***:** * **.** ** *:*:**::*:*:. :.* . .: . *:****:** * *:*: :**:*:. .: **:******* ***:**:*****:******:*. .*::* *::** *:* ***. *:*:******:*.***.****:*:**:*.*:::*******: * *****:****************:************ **** *:*::** :.* **: * *** : ***: .: . :::*: *::*:.*:: **: : :*:* . :.: ** ::*..: . . :***.* *.**:******* :* *:.**** ***:******: * ** ****:** .*************. ** **:** * ***** ::**.**.:********.*:* ****::*******.*:******::**: .. . ", "identical_positions": 279, "similar_positions": 156, "identity": "43.8%" }, { "cls_id": "homologset.agr.SGD:S000002445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8QI34-1", "uniprot_id": "A8QI34_DROME", "id": "A8QI34-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "MPPKKKNKEHKINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNILTPQPPTPKWIVFLKTMFGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKN-----LAFFSTNVLEGTCRGVVIATGDSTVMGRIANLAAGLDDVQSP-------------------------ISREIQLFIRFITIFAIILGLSFFAISLTLGYEFIDAVVFLIGIIVAN--VPEGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQI--IVESDTTESFRGS-----------------------------HFKIEDKSFNALFMCAALCNSAEFKGGQDDIPVFKKDVN------GNASEAALLKFTETIFAGIGAFR-------------------------QKHIKLTEIPFNSTEKYQVSVHEFNSSDGYFIVEMKGAPERILDRCSTIIIQG--LSVELTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFSADPPNFPLEN-LRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFDIP-----LALGTIAILCIDIGTDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLILMAYLQIGVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLICKTRRNSILQQGMGNHVLNFALVLEFIIACLLCYVPVFEKTLRMYSIK------FIWWIYAFPFGLLIFFFDESRRFLIRRNPGGWVEQETYY------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12691-1", "uniprot_id": "ATN5_YEAST", "id": "Q12691-1", "name": "Sodium/potassium exporting P-type ATPase 5", "aln": "----------MSEGTVKENNNEEFN-----AYHTLTTEEAAEFIGTSLTEGLTQDESLRRLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFA-------------VRDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYG-KGAFESIISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPT------------NLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLP--LVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPND--SEVGIFTWEVIIDTFAYGIIMTGSCMASFTG--SLYGINSGRLG---HDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNSENDLERSSKHDPFEAYSTSTTLQSEINISVKH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *::: :.*: *.:..:* * : *. . **: *: **: * * * :. :.*: : ..: ::* . :.*. : * .::.:: *. *: .* :*::. *:*:*** . * ***:*: :*:.*.::* *** **.** :***:*::*::.:..*:* ***** * :.:::.. : **. *** *: *::* .:*:** *. .: :*:**: * ..: * :. :: : :::: : :.: * * :: :* * : .* ** :*..*:*.:*: ::: * *.*:* :*::*:::*:**:.. ***********.:* . ::* :: *. *:: :.*. . : :: :*.: : : : * : .***.*.. *:.:* *: *: .: .*: :. :::*:**:** * **: * .: * * *** * *:. **: :. . ** :.: .:.. * ******. :. .: . . . . . *. * *****.: **** ...** * :.**:.* *:***. ******:.***:.* .: . ... . ::*: *.:: :. **:* : :*:** *** *: ::** :** :: *:*********:** *::*:****.******:*:*::* *******: .:**** : **::* : *:.*:.: : ::: ::* :.*..: :* * : *. :**:.*. *** .*:* * *.* .: : . ::: : *:* * :*: :* . : :*: ..** .* *.. .. .* * .. : . : .*.: : . .: :.:::. **:.* ::::: *: * : *:**::..: ::. * : ** :* :: .: * * :* .. : * ", "identical_positions": 282, "similar_positions": 359, "identity": "24.72%" }, { "cls_id": "homologset.agr.SGD:S000002446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8QI34-1", "uniprot_id": "A8QI34_DROME", "id": "A8QI34-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "MPPKKKNKEHKINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNILTPQPPTPKWIVFLKTMFGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKN-----LAFFSTNVLEGTCRGVVIATGDSTVMGRIANLAAGLDDVQSP-------------------------ISREIQLFIRFITIFAIILGLSFFAISLTLGYEFIDAVVFLIGIIVAN--VPEGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQI--IVESDTTESFRGS-----------------------------HFKIEDKSFNALFMCAALCNSAEFKGGQDDIPVFKKDVN------GNASEAALLKFTETIFAGIGAFR-------------------------QKHIKLTEIPFNSTEKYQVSVHEFNSSDGYFIVEMKGAPERILDRCSTIIIQG--LSVELTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFSADPPNFPLEN-LRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFDIP-----LALGTIAILCIDIGTDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLILMAYLQIGVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLICKTRRNSILQQGMGNHVLNFALVLEFIIACLLCYVPVFEKTLRMYSIK------FIWWIYAFPFGLLIFFFDESRRFLIRRNPGGWVEQETYY------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01896-1", "uniprot_id": "ATN2_YEAST", "id": "Q01896-1", "name": "Sodium/potassium exporting P-type ATPase 2", "aln": "----------MSEGTVKENNNEEFN-----AYHTLTTEEAAEFIGTSLTEGLTQDESLRRLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFA-------------VRDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYG-KGAFESIISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPT------------NLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLP--LVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPHDSEVG--IFTWEVIIDTFAYGIIMTGSCMASFTG--SLYGINSGRLG---HDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIGIKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *::: :.*: *.:..:* * : *. . **: *: **: * * * :. :.*: : ..: ::* . :.*. : * .::.:: *. *: .* :*::. *:*:*** . * ***:*: :*:.*.::* *** **.** :***:*::*::.:..*:* ***** * :.:::.. : **. *** *: *::* .:*:** *. .: :*:**: * ..: * :. :: : :::: : :.: * * :: :* * : .* ** :*..*:*.:*: ::: * *.*:* :*::*:::*:**:.. ***********.:* . ::* :: *. *:: :.*. . : :: :*.: : : : * : .***.*.. *:.:* *: *: .: .*: :. :::*:**:** * **: * .: * * *** * *:. **: :. . ** :.: .:.. * ******. :. .: . . . . . *. * *****.: **** ...** * :.**:.* *:***. ******:.***:.* .: . ... . ::*: *.:: :. **:* : :*:** *** *: ::** :** :: *:*********:** *::*:****.******:*:*::* *******: .:**** : **::* : *:.*:.: : ::: ::* :.*..: :* * : *. :**:.*. *** .*:* * *:*. . : . ::: : *:* * :*: :* . : :*: ..** .* *.. .. .* * .. : . : .*.: : . .: :.:::. **:.* ::::: *: * : *:**::..: ::. * : ** :* :: .: * * :* . : *: ", "identical_positions": 282, "similar_positions": 359, "identity": "24.72%" }, { "cls_id": "homologset.agr.SGD:S000002447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8QI34-1", "uniprot_id": "A8QI34_DROME", "id": "A8QI34-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "MPPKKKNKEHKINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNILTPQPPTPKWIVFLKTMFGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKN-----LAFFSTNVLEGTCRGVVIATGDSTVMGRIANLAAGLDDVQSP-------------------------ISREIQLFIRFITIFAIILGLSFFAISLTLGYEFIDAVVFLIGIIVAN--VPEGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQI--IVESDTTESFRGS-----------------------------HFKIEDKSFNALFMCAALCNSAEFKGGQDDIPVFKKDVN------GNASEAALLKFTETIFAGIGAFR-------------------------QKHIKLTEIPFNSTEKYQVSVHEFNSSDGYFIVEMKGAPERILDRCSTIIIQG--LSVELTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFSADPPNFPLEN-LRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFDIP-----LALGTIAILCIDIGTDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLILMAYLQIGVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLICKTRRNSILQQGMGNHVLNFALVLEFIIACLLCYVPVFEKTLRMYSIK------FIWWIYAFPFGLLIFFFDESRRFLIRRNPGGWVEQETYY------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13587-1", "uniprot_id": "ATN1_YEAST", "id": "P13587-1", "name": "Sodium/potassium exporting P-type ATPase 1", "aln": "----------MGEGTTKENNNAEFN-----AYHTLTAEEAAEFIGTSLTEGLTQDEFVHRLKTVGENTLGDDTKIDYKAMVLHQVCNAMIMVLLISMIISFA-------------MHDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYG-KGAFESIISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPT------------NLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLP--LVIARCSPQTKVRMIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPHDSEVG--IFTWEVIIDTFAYGIIMTGSCMASFTG--SLYGINSGRLG---HDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIGIKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *::: .*: *.:..:* * : *. . **: * **: * * * :. :.*: : ..: ::* . ::.*. .: * .::.:: *. *: .* :*::. *:*:*** . * ***:*: :*:.*.::* *** **.** :***:*::*::.:..*:* ***** * :.:::.. : **. *** *: *::* .:*:** *. .: :*:**: * ..: * :. :: : :::: : :.: * * :: :* * : .* ** :*..*:*.:*: ::: * *.*:* :*::*:::*:**:.. ***********.:* . ::* :: *. *:: :.*. . : :: :*.: : : : * : .***.*.. *:.:* *: *: .: .*: :. :::*:**:** * **: * .: * * *** * *:. **: :. . ** :.: .:.. * ******. :. .: . . . . . *. * *****.: **** ...** * :.**:.* *:***. ******:.***:.* .: . ... . ::*: *.:: :. **:* : :*:** *** *: ::** :** :: ::*********:** *::*:****.******:*:*::* *******: .:**** : **::* : *:.*:.: : ::: ::* :.*..: :* * : *. :**:.*. *** .*:* * *:*. . : . ::: : *:* * :*: :* . : :*: ..** .* *.. .. .* * .. : . : .*.: : . .: :.:::. **:.* ::::: *: * : *:**::..: ::. * : ** :* :: .: * * :* . : *: ", "identical_positions": 281, "similar_positions": 360, "identity": "24.63%" }, { "cls_id": "homologset.agr.SGD:S000002448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFB2-1", "uniprot_id": "RT10_DROME", "id": "Q9VFB2-1", "name": "Small ribosomal subunit protein uS10m", "aln": "MKMHMKHLDLYSQAIKTLRWTQPMRALSTVNTSSGVQGNLSPAAPAPEPDKLYSKLEIELRGIDPAVLKSYTWFATTAAEHLGIEKGKCWSPRKAHHERMTLLKSVHIYKKHRVQYEVRTHFRYMNFHKLTGSTLDTFLEYIERNLPEGVALQASRTELQEIPEHLRQPPEQV--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03201-1", "uniprot_id": "RT10_YEAST", "id": "Q03201-1", "name": "Small ribosomal subunit protein uS10m", "aln": "-------MLRNTIALRSFIRTQSTRPYP-VNVEAVYYAPLKLPIKYGD-----LVADIQLRSYDNENLDFYSDFILRTGYYLGIP-LTGPKPLPTRRERWTVIKSPFVHAKSKENFERHTHKRLIRAWDTNPEVLQMLIAYITKHSMAGVGMKCNFFQRSEISLDLGSDANGLEKSLSNIDELYSLRNDDKAQTSAVGQKVLELLDSPDFKKHLEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:::: **. *. . **..: . *. . : :*:**. * *. *: * :. :*** . .* :::** *::** .:: * : ::* :** * :. . . ..*: :: ** :: **.::.. : .**. .* . .: : ", "identical_positions": 36, "similar_positions": 62, "identity": "16.59%" }, { "cls_id": "homologset.agr.SGD:S000002450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TTC2-1", "uniprot_id": "TYY2_MOUSE", "id": "Q3TTC2-1", "name": "Transcription factor YY2", "aln": "MASETEKLLCLNTESAEIPADFVELLPPDNIGDIEAVSLETSVGQTIEVYGDVGVDWAHGSQYHSPVIALQPLVGSSLSSRDHDKEMFVVQTREEEVVGYQDSDNLLFSPEFGSQMVLPVNEDDYLQPTTASFTGFLAAENGQGELSPYEGNLCGLTTFIEAGAEESVNADLGDKQWEQKQIDGLDGEFPFTMWDDVNEKEDPIAEEQAGESPPDYSEYMTGKKFPPEGIPGIDLSDPKQLAEFTSMRPKKPKGDFPRPIACSHKGCEKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03125-1", "uniprot_id": "NRG1_YEAST", "id": "Q03125-1", "name": "Transcriptional regulator NRG1", "aln": "------------------------MFYPYNYSNLNVSTMPALPG-------------------------------------------------ISAFDGMQDEENVEISPERKYQTLLPVLTNSHVVENELKHKLNKTAFDFR----------------------YQTKSENGSEKWEPKYLITPNLQTRSVSFDNSSVQYNSDSSEKSSLSQLTCNSSIIQQ--PENGIVSNDAYNKMANSRYS-LKTRKQRTDP-----------------RNTLSDEEDLEQRRKYICKICARGFTTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDNCLQHYRTHLKKGQ--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * .:::. :: : * . . * **.:*: :*** * :*** :.:: . ... :* : : ..::: *.::** * : : : . :*: . : :. :.*::. * .. : : * :** . * : :.:: ::.:* : * ..:: .. .:. * ::* *.:.*. *.:* **: :***** : *.::** :*** . * * * * . ", "identical_positions": 51, "similar_positions": 93, "identity": "13.49%" }, { "cls_id": "homologset.agr.SGD:S000002451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36552-1", "uniprot_id": "HEM6_MOUSE", "id": "P36552-1", "name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "aln": "MALRLGRLGSDPWWRAVLG-----------DYAQLRAASPRCASARVCQLPGTAGPQPRRGLGYGPWARGGSGLGTRLAATLAGLAGLAAAAFGHVQRAEMVPKSSGARSPSPGRREEDGDELARRCSTFMSSPVTELRELRRRPEDMKTKMELMIMETQAQVCRALAQVDGV-ADFTVDRWER-KEGGGGITCVLQDGRVFEKAGVSISVVHGNLSEEAANQMRGRGKTLKTKD---------SKLPFTAMGVSSVIHPKNPYAPTMHFNYRYFEVEEADGNTH-WWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDIYPKFKKWCDDYFFIVHRGERRGIGGIFFDDLDSPSKEEAFRFVKTCAEAVVPSYVPIVKKHCDDSYTPRDKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPPENSKEAEILEVLRHPKDWVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B7D0-1", "uniprot_id": "HEM6_RAT", "id": "Q3B7D0-1", "name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "aln": "MALRLGQLGSGPWWRAVRG-----------DYAQLRAPSPRSASACVCRLPGTAGTQPRRGLGHGSSAGGGSRLGTGLAAALAGMAGLAAAVLGHVQRAEMVPKSSGARSPSPGRLEEDGDELARRCSTFMSSPVTELRELGRRPDDMKTKMELMIMETQAQVCRALAQVDGV-ADFSVDRWER-KEGGGGITCVLQDGRVFEKAGVNISVVHGNLSEEAANQMRSRGKALKKKD---------GKLPFTAMGISSVIHPKNPYAPTMHFNYRYFEVEEADGKMH-WWFGGGCDLTPTYLNREDAVHFHRTLKEACDQHGPDIYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEAFRFVKTCAEAVVPSYVPIVKKHCDDSYTPQDKLWQQLRRGRYVEFNLVYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPPENSKEAEILEVLRHPKDWVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36551-1", "uniprot_id": "HEM6_HUMAN", "id": "P36551-1", "name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "aln": "MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGG-ANFSVDRWER-KEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKD---------GKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQ-WWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3D2-1", "uniprot_id": "HEM6_DROME", "id": "Q9V3D2-1", "name": "Oxygen-dependent coproporphyrinogen-III oxidase", "aln": "------------------------------------MNALRHTISLVS-----LGTFQLVRRTRGPHARG-FLLGTGL-----GLASFSAVTYAHSA-EAVDPKVNGVQMNT---------------SRFMAEPITDSKALLGDKENMRHRMEILIMEIQAEFCRALEAEENCGQKFKVDRWER-PEGGGGITCVLQDGDVFEKAGVNISVVTGSLPPAAVQQMRARGKNLKEG----------ASLPFFASGVSAVIHPRNPHVPTIHFNYRYFEVETAKGEKQ-WWFGGGTDLTPYYLCEKDASHFHQTLKSACDEHDPTYYPRFKKWCDDYFRIKHRNESRGIGGIFFDDIDSPNQEAAFNFVSSCARAVIPSYVPLVRKHKNREYGNNERQWQLLRRGRYVEFNLIYDRGTKFGLYTPGARYESILMSLPLHARWEYMHEPKSQSEEGKLMKVLKNPKDWV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11353-1", "uniprot_id": "HEM6_YEAST", "id": "P11353-1", "name": "Oxygen-dependent coproporphyrinogen-III oxidase", "aln": "----------------------------------------------------------------------------------------------------------------------------------MPAPQ-DPRNLP-----IRQQMEALIRRKQAEITQGLESIDTV--KFHADTWTRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVEDCFDAFLPSYLTIVKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRGTQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVTTKPREWVK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * : * :: :** :* . **:. :.* : .* .* * * :**** : *:*** .***.**.:*** *.*. *.. *:. * *: : * * *:* **** **:.** *:******. .* : ****** **** ** .:*. **: *.* *:*.. **:******:** * ** * ********** *. . : :.:*. * *.:***:.:*::: : : .:: ** :**********:*****:*** ***:* ******** * * * * * *.*.::::* :*::** ", "identical_positions": 149, "similar_positions": 79, "identity": "31.97%" }, { "cls_id": "homologset.agr.SGD:S000002452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2Y1-1", "uniprot_id": "RPC10_HUMAN", "id": "Q9Y2Y1-1", "name": "DNA-directed RNA polymerase III subunit RPC10", "aln": "-----MLLFCPGCGNGLIVE---EGQRCHRFACNTCPYVHNITR-KVTNRKYPKLKEVDDVLGGAAAWENVDSTAESCP---KCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWRD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQZ7-1", "uniprot_id": "RPC10_MOUSE", "id": "Q9CQZ7-1", "name": "DNA-directed RNA polymerase III subunit RPC10", "aln": "-----MLLFCPGCGNGLIVE---EGQRCHRFACNTCPYVHNITR-KVTNRKYPKLKEVDDVLGGAAAWENVDSTAEPCP---KCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWRD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2B2-1", "uniprot_id": "A0ABK0M2B2_RAT", "id": "A0ABK0M2B2-1", "name": "DNA-directed RNA polymerase III subunit RPC10", "aln": "TSAAPHRAAVWELSNAAVLPGLRERPHCGGGAALSPLRLQHVP---VTNRKYPKLKEVDDVLGGAAAWENVDSTAEPCP---KCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWRD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1ZBX4-1", "uniprot_id": "A1ZBX4_DROME", "id": "A1ZBX4-1", "name": "DNA-directed RNA polymerase subunit", "aln": "-----MLFFCPSCGNILIIE---EDTNCHRFTCNTCPYISKIRR-KISTKTFPRLKEVDHVLGGKAAWENVDSTDAECP---TCGHKRAYFMQIQTRSADEPMTTFYKCCNHECNHTWRD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04307-1", "uniprot_id": "RPC10_YEAST", "id": "Q04307-1", "name": "DNA-directed RNA polymerase III subunit RPC10", "aln": "-----MLSFCPSCNNMLLITS--GDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGG--GWDNVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVN--CGHRWKEN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :: :. : : : :. ****.**** .*:***.* ** .* ***:*:* ************* * *.* *:: ", "identical_positions": 39, "similar_positions": 20, "identity": "32.23%" }, { "cls_id": "homologset.agr.SGD:S000002453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "-----------------------------MARGLPTI------------ASLARLCQKLNRLKPLE--------DSTMETS----LRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPA-VLLSFGVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLG--HYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWH---------SLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS-----------------------------PPSSPGPASPGPLTKQ-------QSSFSD------------------------------HLQLVGTVHASVPE----------PGELKPALRPYLGFLDGYS-------PGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQR----------------------------------ELPGLNSTHYVVFPRGS---------------------------------------LEETVQAMQPPSQAPAQDPGHME---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "-----------------------------MARGLPST------------ARLARFCQKLNRLKPLE--------ESSTETS----LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPA-VLLSFLVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWH---------SLDPDSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCPASPGPTVKK-------YDSFSD------------------------------HIQLVDAVQASMSE----------PGQLRPALKPFLGFLDGLS-------PGTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPDSQTPVQGPGCTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "-----------------------------MSGFLSSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTK----LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPG-VIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYY---------AIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCG--AKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXR1-1", "uniprot_id": "S7A14_MOUSE", "id": "Q8BXR1-1", "name": "Solute carrier family 7 member 14", "aln": "-----------------------------MSGFLASLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTSAHGTK----LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPG-VIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHSISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYY---------AIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCG--AKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSEYISGQSWWAILLVVLMMLLISVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIANDELDCSPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "-----------------------------MSGFFTSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTK----LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPG-VIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYY---------TIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCG--AKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "---------------------------MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPK----LTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPG-VIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWSEHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYD---------HINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTP---VAHGTASDSRSHVTPAEVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41815-1", "uniprot_id": "BAP3_YEAST", "id": "P41815-1", "name": "Valine amino-acid permease", "aln": "MSDPIVTSSKMEKSAEFEVTDSALYNNFNTSTTASLTPEIKEHSEESRNGLVHRFVDSFRRAESQRLEEDNDLEDGTKSMKSNNHLKKSMKSRHVVMMSLGTGIGTGLLVAN-AKGLSLAGPGSLVIGYVMVSFVTYFMVQAAGEMGVTYPTLPGNFNAYNSIFISKSFGFATTWLFCIQWLT-VLPLELITSSMTVKYWNDTINADVFIVIFYVFLLFIHFFGVKAYGETEFIFNSCKILMVAG--FIILSVVINCG--GAGVDGYIGGKYWRDPGSFAEGSG---ATRFKGICYILVSAYFSFGGIELFVLSINEQSNPRKSTPVAAKRSVYRILIIYLLTMILIGFNVPHNNDQLMGSGGSATHASPYVLAASIHKVRVIPHIINAVILISVISVANSALYAAPRLMCSLAQQGYAPKFLNYID-REGRPLRALVVCSLVGVVGFVACSPQEEQAFTWLAAIAGLSELFTWSGIMLS--------------------------------------------------------------------------------------------HIRFRKAMKVQGRS------------------LDEVGYKANTG------------------------------------IWGSYYGVFFNMLVFMAQFWVALSPIGNGGKCDAQAFFES---YLAAPLWIFMYVGYMVYKRDFTFLNPLDKIDLDFHRRVYDPEIMRQ-----------------------------------------------------------------------------------------------EDEENKERLKNSSIFVRVYKFWC--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : . . . * : :.: .: :.:* *:*: : . .:***. :::.: :.:..: : . .*:*. * *. :. : :.: .* * . :::: . *. ..:* : : . .: . :. :. . : * :: . . :.*: .:.:::* *::::. : :* **. : * * *: *: . :: : ** :. :: .: . ::. **:: ::* :* : : : * . : .. .. : . : :.:: . : : . :: : . * . : .: : : : : : : ..: : : : :. :* :. :.: . . . ", "identical_positions": 36, "similar_positions": 163, "identity": "4.13%" }, { "cls_id": "homologset.agr.SGD:S000002454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32362-1", "uniprot_id": "DCUP_RAT", "id": "P32362-1", "name": "Uroporphyrinogen decarboxylase", "aln": "----NGLGL-QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLEPVRRFP--LDAAIIFSDILVVPQALAMEVTMVPGKGPSFPEPLREERDLERLRD-PAAVASELGYVFQAITLTRQQLAGRVPLIGFAGAPWTLMTYMVEGGSFKTMAQAKRWLYQKPVASHKLLGILTHALVPYLIGQVAAGAQALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAG-LTRMPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAREPVGKTVTLQGELDPCALYASEEEIGRLVQQMLNDFG--PQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70697-1", "uniprot_id": "DCUP_MOUSE", "id": "P70697-1", "name": "Uroporphyrinogen decarboxylase", "aln": "-MEANGFGL-QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFP--LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRD-PAAAASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGSSSTMAQAKRWLYQRPQASHKLLGILTDVLVPYLIGQVAAGAQALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAG-LAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARERVGKAVTLQGNLDPCALYASEEEIGRLVQQMLDDFG--PQRYIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06132-1", "uniprot_id": "DCUP_HUMAN", "id": "P06132-1", "name": "Uroporphyrinogen decarboxylase", "aln": "-MEANGLGP-QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFP--LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRD-PEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAG-LAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFG--PHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTS2-1", "uniprot_id": "DCUP_DANRE", "id": "Q9PTS2-1", "name": "Uroporphyrinogen decarboxylase", "aln": "MMDKDSFILPKDFPELRNDTFLRAARGEEIEHIPVWCMRQAGRYLPEFRESRAGKDFFETCRSPEACCELTLQPLRRFP--FDAAIIFSDILVVPQAMGMEVQMCPGKGPTFPEPLKEPEDLQRLKT-QVDVYSELDYVFKAITLTRHKIEGKVPLIGFTGAPWTLMSYMIEGGGSATHSKAKRWLYRYPEASHKLLSQLTDVIVEYLLGQVKAGAQALQVFESHTGCLGPVEFKEFSLPYLRDIARRVKDKIKESG-LDNVPMIVFAKDGHYGLEDLSESAYEVVGLDWTIDPRSARVRTGGKVSLQGNMDPCALYGTKESISEIVRRMLEGFG--TKGYIANLGHGLYPDMDPENVGAFVEAVHNHSRQLLKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V595-1", "uniprot_id": "DCUP_DROME", "id": "Q9V595-1", "name": "Uroporphyrinogen decarboxylase", "aln": "------MKDAKPFPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLPEFQELRKHHDFFTVCRTPELACEVTMQPLRRFD--LDASIIFSDILVIPQALGLTVEMHAGVGPVLPQPIVVPEDLKRLT--PDGALSRLSYVGDAITMMRHKLEGRVPLIGFTGAPWTLMGYMIEGGGSKTMSKAKAWLNEHPEDSKLFLNLLTDAIVDYLEMQVKAGAQMLQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKA-IPVVPMTLFAKGAGHSLKEQSELGYDVIGLDWTVDPLEARNLVGPNITLQGNLDPQDMYRDPDELRNLTTEMVHKFG--KSRYIANLGHGITPQTPITSMEVLVEAVHKAL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32347-1", "uniprot_id": "DCUP_YEAST", "id": "P32347-1", "name": "Uroporphyrinogen decarboxylase", "aln": "------MGN---FPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVYMTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHRIGSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :** :**** ** : * * **********::* : :*** .** .* ..*:*::*:**: :**:********:***:.: * * * ** :*:*: .**: : . ..*.:. .***: * :: *.***:** *.***** ** ***. ** *: * *: :* :*.. * :* ** **** **:*** *. * ::.:**:: : .: : : . : :** :***.. ..*.. . .::*:.***: * .* ::***::** :* : : . . .*:. ** **.*:*** * : ::: *. ", "identical_positions": 131, "similar_positions": 100, "identity": "34.93%" }, { "cls_id": "homologset.agr.SGD:S000002456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H85-1", "uniprot_id": "ANKZ1_RAT", "id": "Q66H85-1", "name": "tRNA endonuclease ANKZF1", "aln": "--------------------------MLPAPRAAPVPASVSLLTLNGEAPLVRGLSLVSQAPGEALAWAPRTSCPG--ENTSSGRKVSPCSLDISDKLFCSACDQVFQNHQEQREHYKLDWHRFNLKQRLKNKPLLSASDFE----RQSSRGDLSSISGSEDSDSASE---EDLLTLDEERAESEKPNRPPGFYPHRVLFRNAQG-----------------------QFLYAYRCVLGPHQIPPEKAELLLQNLQNGGPRHYVVLMAAAGHFAGAIFQGR--------------------EVVAHKTFHRYTVRAKRGTAQGLQDAQGR--ASRSAGANLRRYNEAMLYKDVRDLLAGPTWSKALGEAETILLHAPRSGRSLFFGGQGAPLQRSDFRLWDIPLTTRRPTFGELQRVLHKLTTLQVYDEDPREMVRFHSPETHCKPVREERKRDTEKEKTKVPSDANKALGQDEEPLKQGSESQEEDGSEVELELVELTLGTLDLREFEVLP--KRRKK-RKKKERSQKQQCG-----------------AHGPLLQ-------QPQDE-PFSQPTQVVATPLDTLVDEAKAPGQPELWDMLLAACRAGEVEVLK--LQLATG---------PVDPGVMS--LLSAPLGSGGFTLLHAAAAAGRGLVVRLLLEAGADPTVHDSRARPPYTVAADRSTRNEFRRFMEKNLDAYD-YSKARVPGPLTQEMEARQATRKKEQKAARRQREQQQRKQREQEEQEQEERRRFAALSDREK-RALAAERRLAAQLGAPSPPVPDSAVVNAGRCWSCGVSLQGLIPFHYLDFSFCSTRCLRDHRSQAGRPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UU1-1", "uniprot_id": "ANKZ1_MOUSE", "id": "Q80UU1-1", "name": "tRNA endonuclease ANKZF1", "aln": "MAKPAGDAAVGSRSGELFLPSVSSSATSPAPSAAPAPASVSLLSLNGEAPLIRGLSLVSQAPGEALAWAPRTSCPG--ENTSSGGKVSPYSLEISEKLFCSACDQIFQNHQEQREHYKLDWHRFNLKQRLKNKPLLSASDFE----QQSSTGDLSSISGSDDTDSSSE---EDLLPLDEGRAESEKPNRPPGFYPHRVLFKNAQG-----------------------QFLYAYRCVLGPHQIPPEKAELLLQNLQNGGPRYYVVLMAAAGHFAGAIFQGR--------------------EVVAHKTFHRYTVRAKRGTAQGLQDAHGR--ASRSAGANLRRYNEAMLYKDVRNLLAGPIWSKALGEAETVLFRAPRSGRSLFFGGQGAPLQRDDPRLWDIPLTTRRPTFGELQRVLHKLTTLQVYDEDPREMVRFHSPETHWKPVREERKKDTEKEKTKVPSDANKPLGQDEEPLKQGSESQEEDGSEVELELVELTLGTLDLREFEVLP--KRRRR-RKKKERSQEQQCG-----------------AHGPLPQ-------QPQDE-PFSQPTQEVETPLDTLVYEAKAPGQPELWDTLLAACRAGEVEVLK--LQLATG---------LVDPGVKS--LLNAPLGSGGFTLLHAAAAAGRGLVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNLDAYD-YNKARVPGPLTQEMEARQATRKKEQKAARRQREQQQRKQREQEEQEQEEQRRFAALSDREK-RALAAERRLAAQLGAPSPPVPDSAVASAGRCWSCGVSLQGLIPFHYLDFSFCSTRCLRDHRSQAGRPSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8Y5-1", "uniprot_id": "ANKZ1_HUMAN", "id": "Q9H8Y5-1", "name": "tRNA endonuclease ANKZF1", "aln": "--------------------------MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERKLLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFE----KQSSTGDLSSISGSEDSDSASE---EDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQG-----------------------QFLYAYRCVLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGR--------------------EVVTHKTFHRYTVRAKRGTAQGLRDARGG--PSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPRSGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLP--KRRRRKRNKKEKSRDQEAG-----------------AHRTLLQ-------QTQEEEPSTQSSQAVAAPLGPLLDEAKAPGQPELWNALLAACRAGDVGVLK--LQLAPS---------PADPRVLS--LLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYD-YNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREK-RALAAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQAGRPSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z8J2-1", "uniprot_id": "A0A8M6Z8J2_DANRE", "id": "A0A8M6Z8J2-1", "name": "tRNA endonuclease ANKZF1", "aln": "--------------------------------MSSSPELRSVFTLCGDQTVSCGLREVSALLDQTDPPQPIPYTED----AVPRKTMSAG--EVSDRMFCHACQCPFESREEQMEHYKLDWHRFNLRQRLEGRSAVTVEEFE----KKTGTGDISSISGSDSSDSEDGDLGDEVAPVQTDCALDTD--QPQSRLSAKVVFQNAEG-----------------------QFLSLYRCILQSKKD--NEEDLVSSLLKISNNTVWVILMTGGGHFAGAVFKGK--------------------EILQHKTFHRYTVRAKRGTAQGLRDSQNRSHTPKSAGAALRRYNEAALHKDIHDLLES--WVDYLKEASAIFLRAPSYNKTIFFGGRGAPLDKKDQRMRILPFATRRATFSEVKRVFDLLSTLHVYQKET-EISSILSPS------RRLWKKKTPKPVSHPVPNTN--VPAEGEDAKEESSGEDDSG---TLETVEVTLGTLVLREHEIYPNKKKRRKRKEKREDSSSRETNEDKADDENMDEGELEVESDSKEMQRKSRGRRKPKGKKPQPEEGKLILELTQMFNYEVDESWEYSLRDALYTACKTGDIQSLRSLLHLPEDEESRRERTTEEDPASQSSDLLNKPIDSAGFTLLHVASAAGQKSVIRLLMDAGSDPANKTKKGQTPYGVAPEKDTRNVFRKYMAEHPHKYD-YTKAQVPGPLTEDIESKKAEKKKAQKAARKQKEKEQKEEKVKKQQEEEEKKRFTALSDREK-RALAAERRLAEHLATTG-----GALNNIRRCFLCGESLLGKIPFEYLDYSFCTPRCVQAHRKANAAARP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04311-1", "uniprot_id": "VMS1_YEAST", "id": "Q04311-1", "name": "tRNA endonuclease VMS1", "aln": "------------------------MNSQKASKMTGSLKKNDLYIFDLSEQLLNSLKLMSFDSTLREVEVEKTSDND--RNKESGDLQIARKKVTSNVMRCSVCQMSFDSRNEQKAHYQTDYHLMNVKRNLRGLDILSVEEFDALISKEHGIKSEDENSGGEQTSSDHEE-SEEASDRDPDLQTNNYMETIIENDLQKLGFQKDESDAISHINTQSPYIYFKSKYLQKNEVLAIYKSLFNKRSLSNPNEALTFWNSQENPMAISALFMVGGGHFAGAIVSHQRLNVKGNAHKKDETLIEQAVNFLEHKTFHRYTTRRKQGGSQSAMDNAKG--KANSAGSALRRYNESALKTDIQGVLKD--WEPYLSKCDNIFIRARNVSDKKIFTDN-TVLNKGDERIKSFPFTTNRPTVLELKKAWCELSYLKILPKPE-----------------PLAVKETVQKLEVS------------------------------------------------------------------------------------------------------NKKDEFKEKQEPLLEEIQTEEIISLLKKGRAPLLISFLKKNKLDGNFRLKP-----------------------------ESKYSLTPTMLHYASQQGMKQMALILLSNIKCDPTIKNRLGRTAWDLNRNDDVRHAFQIARYNLGESFTNWDETHIGQPLSREQVDEINEKKKAIENEKAEKLIKLELEAAK------EKQRFAKDAERGPGKKLTNIPSIQQQNLNSLTDEQRRRLMREQRARAAEERMKKKY---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : . : .* :* . . . *: : * .*: *:.::** **: *:* :*:::.*.. ::. :*: :: . . .. **.:.:.* :: : :: *:: :. :.* *:.:: :. : * : .::*...******:.. : :.: ********.* *:* :*. * ..***: ******: * .*::.:* . * * :. ::::* . . :* .. : *:: * *: :*::*.*.*. *:::. *: *:: : : * : : : : : : . * . * *:. . . * :.: . : .: ** : .**: : .:..: : : ..*: *: : . : : :::: **: : . :*: : : :: : . : : *::**: ::* : *: : : . : *. . : ", "identical_positions": 88, "similar_positions": 189, "identity": "10.41%" }, { "cls_id": "homologset.agr.SGD:S000002457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJE4-1", "uniprot_id": "A0ABK0LJE4_RAT", "id": "A0ABK0LJE4-1", "name": "Triosephosphate isomerase", "aln": "MSSLIPGSFNLPMTIMELNSRKFFVGGNWKMNGKKKCLGELICTLNAAKMPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEEVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48500-1", "uniprot_id": "TPIS_RAT", "id": "P48500-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKKCLGELICTLNAAKLPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHIFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWCKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEGVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60174-1", "uniprot_id": "TPIS_HUMAN", "id": "P60174-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17751-1", "uniprot_id": "TPIS_MOUSE", "id": "P17751-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------TRKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90XG0-1", "uniprot_id": "TPISB_DANRE", "id": "Q90XG0-1", "name": "Triosephosphate isomerase B", "aln": "MSG-----------------RKFFVGGNWKMNGDKKSIEELANTLNSAKLNPDTEVVCGAPTIYLDYARSKLD-PNIDVAAQNCYKVAKGAFTGEISPAMIKDCGVKWVILGHSERRHVFGESDELIGQKVAHALENGLGVIACIGEKLDEREAGITEKVVFAQTKFIADNVKDWSKVVLAYEPVWAIGTGKTASPQQAQEVHDKLRQWLKTNVSEAVANSVRIIYGGSVTGGTCKELASQKDLDGFLVGGASLKPEFIDIINAKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1MTI4-1", "uniprot_id": "TPISA_DANRE", "id": "Q1MTI4-1", "name": "Triosephosphate isomerase A", "aln": "MSS-----------------RKFFVGGNWKMNGDKESLGELIMTLNTASLNDETDVVCGAPSIYLDYARSKLD-QRIGVAAQNCYKVPKGAFTGEISPAMIKDCGIDWVILGHSERRHVFGESDELIGQKVAHCLESDLGVIACIGEKLEEREAGTTEDVVFEQTKVIADNVKDWTRVVLAYEPVWAIGTGKTASPEQAQEVHEKLRGWLRANVSDAVADSVRIIYGGSVTGGNCKELAAQADVDGFLVGGASLKPEFVDIINARS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29613-2", "uniprot_id": "TPIS_DROME", "id": "P29613-2", "name": "Triosephosphate isomerase", "aln": "MSR------------------KFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLP-CELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINARQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00942-1", "uniprot_id": "TPIS_YEAST", "id": "P00942-1", "name": "Triosephosphate isomerase", "aln": "MAR------------------TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINSRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* ****:*:** ::.: *: *.:* : .:** *: *: :: . : .: :..**.* ..****** * :** * **:******* * *.* :*.:*. ..* ..: ** ****.*:*::** * .** * :::*** .**:*********** :*:*::**::* :* :* ::.. .: ** ****...... : : *:**************:****:: ", "identical_positions": 106, "similar_positions": 76, "identity": "39.85%" }, { "cls_id": "homologset.agr.SGD:S000002459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJF6-1", "uniprot_id": "A0A096MJF6_RAT", "id": "A0A096MJF6-1", "name": "Protein DBF4 homolog A", "aln": "-------MNLETMRIHSKAPLPGGIQDKNEKNRPSLKSLKADNRLEK----SKYKPLWGKIFYLDLPSITICEKLQKDIKELGGRVEEFLSKDISYLVSNKKEAKYAQT----LGRVSPVPSPESAYTAETTSPHPSHDGSSFKSQDRVCLSRGKLLAEKAVKDHDFIP------ANSILSNALSWGVKILHIDDIRYYIEQKKKALGALKKPNTSGRDSGKKAGTGIQKARTGRLKKPFLKVEDVNRTYKPFYLQLPS---MPCINYFLQKPCSPFDIDKSSSMQKHTQPKLKI---------NTDGDKYG-TPAQVQLKEK--------------------RKKGYCECCLQKYEDLETHLLSEKHRNFAQSNQ-YQVVDDIVS----------------KLIFDFVEYERDTPKKKRIRYSVGSLSSVSASVLQNTEPREKLLLEPSFQKDGEESNGQLLEQNL--QCEETQKPEEKHVFGSEPTTYSSTGFKGCVGKP---VSLINAS----EPDLKPDCEQLPLRDNKQEGMRVGS-------------------EHKITVDRKDVDQRGGVTPCVPQSC---TYFSTDSNLPQPKLTADITQFSAQDLQEKDLH-VIGHDSELV------------------------TLNSSREQLTVKARPPPCSP-QEPHE--------------------------------GHSEHMESLPCGKIQRKVRMLLGQ-KKANVEPGAEWDKN-----------------------------RTEYLPAHGDRTCGSPVQSLLDLFQTS-------------------GEKSEFLGFTSYTENSGICDVLDIWEEDNSSSLLSTFFSSPSTSAFVGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ41-1", "uniprot_id": "DBF4A_MOUSE", "id": "Q9QZ41-1", "name": "Protein DBF4 homolog A", "aln": "-------MNLETMRIHSKAPLPGGIQDRNEKNRPSLKSLKADNRLEK----SKYKPLWGKIFYLDLPSITICEKLQKDIKELGGRVEEFLSKDISYFVSNKKEAKYAQT----LGRVSPVPSPESAYTAETTSPHPSHDGSSFKSQDRVCLSRGKLLAEKAVKDHDFIP------ANSILSNALSWGVKILHIDDIRYYIEQKKKALSALKKSSASGKDAGKKAGPGIQKTRTGRLKKPFLKVEDVNRCYRPFYLQLPS---LPCINYFLQKPCSPFDIEKSSSVQKQAQPKLRI---------NMDGDKCG-TPVQLQLKEK--------------------RKKGYCECCLQKYEDLETHLLSEKHRNFAQSNQ-YQVVDDIVS----------------QLVFDFVEYGRDTPQKKRIRYSVGSLSSVSANVLKNTAPKEKPLLEPNFQKDVGESSGHLLKPNS--QYEETQKPEEKHGFASEPTTYSSAGLKGCDRKP---VSMFNAS----EPDPEQEYAQLPLRDSTP--------------------------EHQVTEGRNDGEQRVDPAPGVSQSCGQVSHLSTESNLPQPQLAADITQLSAKDLQEKGFHVVIGHASDLV------------------------ALNTSKEQLTMKARTPPCSP-QEPHE--------------------------------CDTENMENLPCGKIQRKVRMLLGQ-QKANAEPSAELDKK-----------------------------RTEYLPAHEDRTCGSPVQSLLDLFQTS-------------------EEKSEFLGFTGYTENSGICDVLDIWEEENSSTLLSTFFSSPSTSAFVGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBU7-1", "uniprot_id": "DBF4A_HUMAN", "id": "Q9UBU7-1", "name": "Protein DBF4 homolog A", "aln": "-------MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEK----SKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQT----LGRISPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIP------SNSILSNALSWGVKILHIDDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTN---MPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRI---------QTDGDKYGGTSIQLQLKEK--------------------KKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQ-YQVVDDIVS----------------KLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNF--LYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTA----EDDIRQNFTQLPLHKNKQECILDIS-------------------EHTLSEN-DLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLI------------------------TINSSQEHLTVQAKAPFHTPPEEPNE--------------------------------CDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDK------------------------------RTEFITQEENRICSSPVQSLLDLFQTS-------------------EEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLTAFFSSPSTSTFTGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NFT6-1", "uniprot_id": "DBF4B_HUMAN", "id": "Q8NFT6-1", "name": "Protein DBF4 homolog B", "aln": "--------MSEPGKGDDCLELESSMAESRLR-APDLGVSRCLGKCQKNSPGARKHPFSGKSFYLDLPAGKNLQFLTGAIQQLGGVIEGFLSKEVSYIVSSRREVKAESSGKSHRGCPSPSPSEVRVETSAMVDPKGSHPRPSRKPVDSVPLSRGKELLQKAIRNQGSISGGGSGGSSSLLTNARSWGVRILHVDEMMMHVQQLSLASLCVKKQQPK-KPEGTCPAAESRTRKVARLKAPFLKIEDESRKFRPFHHQFKS---FPEISFLGPKDASPFEAPTTLGSMHHTRE-------------SKDGEPSP--RSAAHTMPR--------------------RKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIA----------------QLSHSFADIPFQAGLPRWSGSPASDCDPLCPETLHPHQPSHPRAASPRIRKE--DSCQASVTQGR--AAGQQRWTESLDGVMGPPASHTCVSAT----------TLLPAL----PKGSREQGCLCPCP----------------------------------------------------------------ASFTQSHLVTSLALLPGEWSPAEDMP---LHPSQEN------------------------SFAPADIPVKGPLLFPEARPWLMSAR--------------------------------CWVRPFPFVTWGCLIPHDTTPLHE----EVSP-CPCLRL-----------------------------GYLYLLLTQSLWCRVRVPSLSTAGPIPR------------------TSHPCTLAFPSYLNDHDLGHLCQAKPQ--GWNTPQPFLHCGFLAVDSG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NK54-1", "uniprot_id": "CHIF_DROME", "id": "Q9NK54-1", "name": "Protein chiffon", "aln": "--------MQPQSDKQSASRLATTTSHSTAAASATAATPPKVKVIKS------KRPLCHFKFYLDICDHQLAKRIESDIKALGGHLEFFLSDDITHFVTDKPEVIGGTS-----GTPGTPSTPGTPTSHYQQNDGSARKPNQRQSRADAILSRVRRSTVGVVNSGNSTP-----------TTSLKRSYTIWQTDYAQRFIKRIQTELKQYLEGKKEGGGGSTSASP-----HHIQLKKQYVKIESVKRNYRPYYHLIKQPDDWPKIDLSSEDGAFRLLTKSKTKDKEHSMTRKPLGSRTSQKDKQAAGEAKPLQHPSLQELKKQSAIPNSPRSNCREPIDSSEKQGGVCEICKLEYDILNIHLQSKDHELFAKNSDNFLALDTLIQSSADVNRFLEEEPVESELDMDVDESLSNEELQSPRQRPSPALREKSKRITKGKHSSEKFQGVAVASPQTPFPGAKKVQGNSPGSLSELQRQEHPTTAAATPTTNSGRRKTQNSGLSPPKRAMLPPSSIYKVVETREECATPPRGRGRPPNQVDSPSLIVKFQKIRQTELQRLNGEAENFMFPRTAVPTTRSSSELPTDVDRQTTSDVRGRYSISSASLDTSTSEAETKESSGLPTSIRKRAQAVGRRRKVGGAAAQDVFQRQLSTGSSSSNSNQQRFPSAPIQPEEGPQPQPKPQLKIKIKQEQLVATRKSSRTATAIVTAATASSHQQQQLRQTTCRKMANKLEDRMGELVKPKIKIKKEVIEEQKVKELEDLEEILDKELDEEVDSSCSSGSDEDYIAGSQRRITAAPRKSTDTREQRAARRLSRLTINRSAGELELTEVKTSPSKSRTKIQKPSSPTKNKVKQTKAVPPAIDLFFDCSKSERLREMQYTFESLPSGELWNRVFLRQDAGEENYYTYYGSTNYRKLPYEMGPIPMAKTLPAHSCALCREASEVKQDKGEQIKLEDQKPAPKKEVKKEEEVQSSSSSATYKNKKLHLLQRYQQEQEQLQQLEGNSLATAGAKCDSKASTPELLEREFASGSMGDRVQLIERVRSTSSSSCSNSQRSGITCRNKQLARIAELPPRKSPREHASTLALVSCIIRQRQDSQSKTNSEAEEPPPPVAAPKLKTPIKQEPVAPSSPRTTRSQAATPVEELRFATEISETVKRMRRGQNKYDHSPPAPVPTPATSSPVRSRRLTPAARNQSQIYSRRLEFATSQRESSASALLGKRKRRVNPSVAGTVRPTTQNLPGTGAYRGVRKLPSKKGLLEYEMETCALKALDQARQYCNPGFVAWQLDKYLELAGKEYDIEFDQISPEVESEGREERLVNTPQTPPPTDCFTSEFDLCDLIMGSAGSGDDDEDVSRGNPPGSGRRMSNLNLYASYYRKRKSLKSNRTGWPKAQRRRNAGGLGGSRALPDERINFQKMGLAELHPIKQEPMETEEEQTTTTTTTTTTSATRGNLLSKDDEDDEGGGNSPSGGSPADDKQNSREDAVMTPPATDVDEQAEPQADEMESLPDEDETMADSVDQQQDVEAEIEATDADVEEEEEEEDEDEDVFEDAYEEQDMGIQKTEPHEKRARIPSISVTTPPEDSSQGKKLLLTLHNGQRLQATSTPSTGQVQQHQRRTPQLNGSLGSCISPSEKLGDNSDIFTVSSDGLDTDLDLSNTQAGDSHEHCPHQTTPKRKFDISKYAPPNSGKAASSCAAEAATAAVKSLAISQFLKKETCASSSSMRNAWRRTQRRAISAACISAAPSARVPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32325-1", "uniprot_id": "DBF4_YEAST", "id": "P32325-1", "name": "DDK kinase regulatory subunit DBF4", "aln": "MVSPTKMIIRSPLKETDTNLKHNNGIAASTTAAGHLNVFSNDNNCNNNN-TTESFPKKRSLERLELQQQQHLHEKKRARIERARSIEGAVQVSKGTGLKNVEPRVTPKELLEWQTNWKKIMKRDSRIYFDITDDVEMNTYNKSKMDKRRDLLKRGFLTLGAQITQFFDTT-----VTIVITRRSVENIYLLKDTDILSRAKKNYMKVWSYEKAARFLKNLDVDLDHLSKTKSASLAAPTLSNLLHNEKLYGPTDRDPRTK--RDDIHYFKYPHVYLYDLWQTWAPIITLEWKPQE---------LTNLDELPYPILKIGSFGR----------------CPFIGDRNYDESSYKRVVKRYSRDKANKKYALQLRALFQYHADTLLNTSSVN---------DQTKNLIFIPHTCNDSTKSFKKWMQEKAKNFEKTELKKTDDSAVQDVRNEHADQTDEKNSILLNETETKEPPLKEEKENKQSIAEESNKYPQRKELAATPKLN--HPVLATFARQETEEVPDDLCTLKTKSRQAFEIKASG-----------------AHQSNDVATSFGNGLGPTRASVMSKNMKSLSRLMVDRKLGVKQTNGNNKNYTATIATTAETSKENRHRLDFN--------------------------ALKKDEAPSKETGKDSAVHLETNR---------------------------------KPQNFPKVATKSVSADSKVHNDIKITTTESPTASKKST-----------------------------STNVTLHFNAQTAQTAQPVKKETVKNSG------------------YCENCRVKYESLEQHIVSEKHLSFAENDLNFEAIDSLIENLRFQI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. * *:: . . :* :. . :.. . . . . : * : . . : . : : :: : . :: .: : * * : : . . * . : : .: : * :: . : : : . * . . .:: . : . . : . . : . : . . . . :. . :: ", "identical_positions": 9, "similar_positions": 76, "identity": "0.52%" }, { "cls_id": "homologset.agr.SGD:S000002461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A453-1", "uniprot_id": "D4A453_RAT", "id": "D4A453-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "WETRADPAPLPHKPRPTPHPQPRPLDVTEKAPKAAAATPQRAAQPCPPLRTQASAELFRPEATAASGASETQGACAAGRGKKTTLPGVPRGRARRHIPDPVEASHRRILDPAVARRCISGPAAAARSRIRGPGVARRRIRGPKEARRRIRGREPVRRRIRGPAAAARRRVRRGPGRAEASAGRAAAPERVEPSGSPGGGGGGGAEEEGGGSPPAGARPGPSRELAPVPRPGPAPAPGPSAAAAVTAMARPLVPSS--QKALLLELKGLQ--EEPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTD-----------IIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEGSDLFY----------------DDYYED--GEV-EEADS---------------------------CFGDEE----DDSGTEES----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFI2-1", "uniprot_id": "UB2R1_MOUSE", "id": "Q8CFI2-1", "name": "Ubiquitin-conjugating enzyme E2 R1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARPLVPSS--QKALLLELKGLQ--EEPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTD-----------IIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEGSDLFY----------------DDYYED--GEV-EEADS---------------------------CFGDEE----DDSGTEES----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49427-1", "uniprot_id": "UB2R1_HUMAN", "id": "P49427-1", "name": "Ubiquitin-conjugating enzyme E2 R1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARPLVPSS--QKALLLELKGLQ--EEPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTD-----------IIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEGSDLFY----------------DDYYED--GEVEEEADS---------------------------CFGDDE----DDSGTEES----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8I4-1", "uniprot_id": "A0A140T8I4_MOUSE", "id": "A0A140T8I4-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPLVPSS--QKVLLLELKGLQ--EEPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKAHLKFPIDYPYSPPTFWFLTKMWHPNIHETGFVCISILHPPDDNPQGGELPSERWNPTQNVRTILLSVISLLNEPNTSSPANVDASVMYRKWKESKGKDHEYTD-----------IIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEGSDLF------------------DYYVD--GEV-EEADS---------------------------CFGDEE----DDFGPKSPDPRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWZ2-1", "uniprot_id": "UB2R2_MOUSE", "id": "Q6ZWZ2-1", "name": "Ubiquitin-conjugating enzyme E2 R2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQQQMTSS--QKALMLELKSLQ--EEPVEGFRITLVDESDLYNWEVAIFGP-PNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAE-----------IIRKQVSATKAEAEKDGVKVPTTLAEYCIK-TKVPSNDNSSDLLY----------------DDLYDDDIDDEDEEEED---------------------------ADCYDD----DDSGNEES----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q712K3-1", "uniprot_id": "UB2R2_HUMAN", "id": "Q712K3-1", "name": "Ubiquitin-conjugating enzyme E2 R2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQQQMTSS--QKALMLELKSLQ--EEPVEGFRITLVDESDLYNWEVAIFGP-PNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAE-----------IIRKQVSATKAEAEKDGVKVPTTLAEYCIK-TKVPSNDNSSDLLY----------------DDLYDDDIDDEDEEEED---------------------------ADCYDD----DDSGNEES----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8Y4N8-1", "uniprot_id": "A0A8J8Y4N8_RAT", "id": "A0A8J8Y4N8-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQQQMTSS--QKALMLELKSLQ--EEPVEGFRITLVDESDLYNWEVAIFGP-PNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAE-----------IIRKQVSATKAEAEKDGVKVPTTLAEYCIK-TKVPSNDNSSDLLY----------------DDLYDDDIDDEDEEEED---------------------------ADCYDD----DDSGNEES----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUR4-1", "uniprot_id": "Q9VUR4_DROME", "id": "Q9VUR4-1", "name": "UBC core domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTAASTSQHATSSSTMMAGSGSLATSSSAAAPTTTPSSSAVRALAMEYKSLQ--EEPVEGFRVKLINDDNLFEWEVAIFGP-PDTLYQGGYFKAHMKFPHDYPYSPPSIRFLTKVWHPNVYENGDLCISILHPPVDDPQSGELPCERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRRWRDSQGKDNEYPN-----------IIRKQALAANAEAKREGIVVPMTLEDYCLKPTRKPTTESGLDANFYDDDFDLETEDDLPSDDDFDEDDDDDEDEDEDEDSATAPISKNNGGSSKCKNNGLVREAAAAGADDAESADDSGKGETT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62254-1", "uniprot_id": "UB2G1_MOUSE", "id": "P62254-1", "name": "Ubiquitin-conjugating enzyme E2 G1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTELQSA---LLLRRQLAELN--KNPVEGFSAGLIDDNDLYRWEVLIIGP-PDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAA---KEWRED--RNGEFKR-----------KVAR-----------------------CVR----KSQETAFE-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62253-1", "uniprot_id": "UB2G1_HUMAN", "id": "P62253-1", "name": "Ubiquitin-conjugating enzyme E2 G1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTELQSA---LLLRRQLAELN--KNPVEGFSAGLIDDNDLYRWEVLIIGP-PDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAA---KEWRED--RNGEFKR-----------KVAR-----------------------CVR----KSQETAFE-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14682-1", "uniprot_id": "UBC3_YEAST", "id": "P14682-1", "name": "Ubiquitin-conjugating enzyme E2-34 kDa", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKSTAS---SLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQS-GDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRVKMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVILQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFED-----DDDDDDDSIDNDSVMDRKQPHKAEDESEDVEDVERVSKKI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : * ::.: .* * ::.::: *:: :: :: *.** ***:: ** *:* ** : * . ::***: . * :****** . : * * * * :.*.::::*::*:* :** *******: :. :. : : : : . ", "identical_positions": 45, "similar_positions": 54, "identity": "8.15%" }, { "cls_id": "homologset.agr.SGD:S000002464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEH8-1", "uniprot_id": "ERLEC_MOUSE", "id": "Q8VEH8-1", "name": "Endoplasmic reticulum lectin 1", "aln": "MEEGDGGLRSLVPGGPLLLVLYGLLEASGGGRALPQLSDDIPFRVNWPGTEFS----LPTTGVLYKEDNYIIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHE--EKETGQKVNIHEYYLGNMLAKNLLYEKEREAKENEK--SNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPES---KHEILSVAEVTTCEYEVVILTPLLCSHPKYKFRAS--PVNDIFCQSLPGSPFKPLTLRQLEQQEEILRVP----FRRNKEEDLPSAKE------------------------------ERFPAIHKPIAVGSQPVLT---VGTTHISKLTDDQLIKEFLSGS------YCFHGGVGWWKYEFCYG----------------------------KHVHQYHEDKDNGKTSVVVGTWNQEEH-----------------------------------VEWAKKNTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCK-ESDSPHAVTVYMLEPHSCQYILGVESPVICKILDTADENGLLSLPN---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF97-1", "uniprot_id": "D3ZF97_RAT", "id": "D3ZF97-1", "name": "Endoplasmic reticulum lectin", "aln": "MEEGGGGLRSLVPGGPLLLVLYGLLEAAAGGRALPQLSDDIPFRVNWPGTEFS----LPTTGVLYKEDNYIIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHE--EKETGQKVNIHEYYLGNMLAKSLLYEKE-QAKEKEK--SNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPES---KHEILSVAEVTTCEYEVVILTPLLCSHPKYKFRAS--PVNDIFCQSLPGSPFKPLTLRQLEQQEEILRVP----FRRNKEEDLSSAKE------------------------------ERFPAIHKPIAVGSQPVLT---VGTTHISKLTDDQLIKEFLSGS------YCFHGGVGWWKYEFCYG----------------------------KHVHQYHEDKDNGKTSVVVGTWNQEEH-----------------------------------VEWAKKNTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCK-ESDSPHAVTVYMLEPHSCQYILGVESPVICKILDTADENGLLSLPN---------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DZ1-1", "uniprot_id": "ERLEC_HUMAN", "id": "Q96DZ1-1", "name": "Endoplasmic reticulum lectin 1", "aln": "MEEGGGGVRSLVPGGPVLLVLCGLLEASGGGRALPQLSDDIPFRVNWPGTEFS----LPTTGVLYKEDNYVIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHE--EKETGQKINIHEYYLGNMLAKNLLFEKEREAEEKEK--SNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPES---KHEILSVAEVTTCEYEVVILTPLLCSHPKYRFRAS--PVNDIFCQSLPGSPFKPLTLRQLEQQEEILRVP----FRRNKEEDLQSTKE------------------------------ERFPAIHKSIAIGSQPVLT---VGTTHISKLTDDQLIKEFLSGS------YCFRGGVGWWKYEFCYG----------------------------KHVHQYHEDKDSGKTSVVVGTWNQEEH-----------------------------------IEWAKKNTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCK-ESDSPHAVTVYMLEPHSCQYILGVESPVICKILDTADENGLLSLPN---------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC7-1", "uniprot_id": "Q9VKC7_DROME", "id": "Q9VKC7-1", "name": "Endoplasmic reticulum lectin 1", "aln": "------MGKSYVIIARIALLLN--LIIAAVSHEAKDFDDSILYKIDFEVPDLD----VQPS----LGNQLRTFYTPDKEKYDCLIPT----LEHQKEEEKSDKPELSPITLLQPIFSALTCTYRIEAYWSYEICHGHHVRQYHE--ERE-GKNVKFQEYYLGKWTDEKMEILTKAWQADIKAGVKPKYKSLKIDNTRYPYFEMEYSDGTMCDIIN-APRTTMVRYVCYPHG---KNDIYSFKETSSCNYEAIILSSALCPIRALHAEET--KELSIQCFNSESKPHRPLSMLRSELKEWVESEADLLVFKEKATENLWPKTDGDLVTLNYGGDMEK-------------VLLEHFRNGDLKVDGDFQQLLLSIAASETGPTPITDLTPLKDFISGK------NCLTGGNGWWKYEFCYG----------------------------RHVRQFHKDKTS-EVELFLGYFSEEAH-----------------------------------RAWSNANPDKGARR----SGFTTSIWHHYGKGTHCEQIGVPREVDVKLTCTPVTNSGTAVSMYLLEPKTCQYILVVESPTICDLIHNADSQGLVKLENLDKILVTETDKSTTSSASAPAPAPTSSTDEENHP-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q13438-1", "uniprot_id": "OS9_HUMAN", "id": "Q13438-1", "name": "Protein OS-9", "aln": "------MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILP----LPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMR-DAPCLLKTKDWWTYEFCYGRHIQQYHM--EDS---EIKGEVLYLG-YYQSAFDWDDETAKASKQH-------------RLKRYHSQTYGNGSKCDLNG-RPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPS--AAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99220-1", "uniprot_id": "OS9_YEAST", "id": "Q99220-1", "name": "Protein OS-9 homolog", "aln": "--MQAKIIYALSAISALIPLGSSLLAPIEDPIVSNKYLISYIDEDDWSDRILQNQSVMNSGYIVNMGDDLECFIQNASTQLNDVLEDSNEHSNSEKTALLTKTLNQGVKTIFDKLN--ERCIFYQAGFWIYEYCPGIEFVQFHGRVNTKTGEIVNRDESLVYRLGKPKANVEEREFELLYDD--------------VGYYISEIIGSGDICDVTG-AERMVEIQYVCGGSNS-GPSTIQWVRETKICVYEAQVTIPELCNLELLAKNEDQKNASPILCRMPAKSKIGSNSIDLITKYEPIFLGSGIYFLRPFNTDERDKLMVT----------------------------DNAMSNWDEITETYYQKFGN---AINKMLSLRLVSLPNGHILQPGDSCVWLAEVVDMKDRFQTTLSLN-----------------------ILNSQRAEIFFNKTFTFNEDNGNFLSYKIGDHG---------------------------------ESTELGQITHSNKADINTAEIRSDEYLINTDNELFLRISKEIAEVKELLNEIVSPHEMEVIFENMRNQPNNDFELALMNKLKSSLNDDNKVEQINNARMDDDESTSHTTRDIGEAGSQTTGNTESEVTNVAAGVFIEHDEL---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * . . . : : : .: . . : . : . ::. : * :* ** * * .. *:* : . :: . : . . * ..* *.: * : ::* * . * * * : . ** . : . :: : : . : . : . . . : : . .. . . :. . . : : . .. . . * . : . : . ", "identical_positions": 21, "similar_positions": 80, "identity": "3.0%" }, { "cls_id": "homologset.agr.SGD:S000002466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51668-1", "uniprot_id": "UB2D1_HUMAN", "id": "P51668-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "-MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZDK2-1", "uniprot_id": "UB2D1_RAT", "id": "D3ZDK2-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "-MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61080-1", "uniprot_id": "UB2D1_MOUSE", "id": "P61080-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "-MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25867-1", "uniprot_id": "UBCD1_DROME", "id": "P25867-1", "name": "Ubiquitin-conjugating enzyme E2-17 kDa", "aln": "-MALKRINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAREWTRKYAM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15732-1", "uniprot_id": "UBC5_YEAST", "id": "P15732-1", "name": "Ubiquitin-conjugating enzyme E2-16 kDa", "aln": "MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** ***.** ***** **********:****:****.**.* ******::************: ***:********.*.******:.*******:*********** *.********:**:***:*: **: *:***:***:", "identical_positions": 112, "similar_positions": 24, "identity": "75.68%" }, { "cls_id": "homologset.agr.SGD:S000002467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNU1-1", "uniprot_id": "D3ZNU1_RAT", "id": "D3ZNU1-1", "name": "CCAAT/enhancer-binding protein zeta", "aln": "---------------------------MSADQEPLEFLAKNPWRPKEVTEDPDEEDEEDSDEAKNGFSLEEVLRLGGTKQDYLMLATLDENEEVVDGGKKGTIDDLQQ------GELEAFIQNLNLAKYSKS----------------LIEEDEPEKKENTSKKEAKLPKVENKKQKAAEGKK------KNKSVPEQHPESSTVFKAKR-DKQPDAFEFLERQALLLKPGGKWYDMEYSG-------------EFSLEPQP---WDVVSKYKALAEKLYEQEVGLFKNKTS------NQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHTLQFVETLLSLVRKKGSKQQCLMALDTFKELLITDLLPDSRKLRLFSQR--PLHKLEELSSGNKDSRDRRLILWYYEHQLKHLVAEFVQVLETLSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVINKLGDPQNRIATKASHLLEVLLRKHPNMKGVVCGELERLLFRSNISPKAQYYAICFLNQMVLSHEESELANKLITLYFCFFRTCIKKKD---------------------------------------------IESKMLSAILTGVNRAYPYSQIGDDR-----VREQVDTLFKVLHVVNFNTSVQALMLLFQVMNSQQTISDRYYTALYKKMLDPGLTTC--SKQAMFLNLIYKSLKADIM-LRRVKAFVKRLLQVTCTQMPP-FICGALYLVSEILKAKPDLRSQLDDHPESD-EENFVDVGDDSDDEKFTDADRETATDAVEEVEAKEA----EPESSTETEKPKA----ASWVHFDNLKGGKQIKTYDPFGRNPLFCGAEHTNLWELRKLSQHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTDSVVMQPKRKHFMKNVRDLA---------VNSKEFLAKEESQIPVDEVFFYRYYKKVAVTKDKQKRNADEDS------IEDVDDEEFENMIDTFEDDNCFT-------------------PGKDDMDFASNMKK-IKGAKDD--LEDSESSDDELGDLDDDEVSLGSMNDEDF-EIDEDGGTFMDVSDDESDHVPEFGEASPKASTK-------------------KSKRKSEDDFDFAGSFQGQKKKKKSFNDSSLFVSAEEFGHLLDENMGSKFDTTGMNAMANKDNASFKQLKWEAERDDWLHNRDVKSIIKKKKNFRKK--KAPQKPKRQRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53569-1", "uniprot_id": "CEBPZ_MOUSE", "id": "P53569-1", "name": "CCAAT/enhancer-binding protein zeta", "aln": "---------------------------MSADQEPVAFLAKQPWRPKQVTEDPDEEDEEDGDEGKNGFSLEEVLRLGGTKQDYLMLATLDENEEVVDGGKKGTIDDLQQ------GELESFIQNLNLAKYSKS----------------LIEEDEPEKKENASKKEAKLLKVENKKQKATEGKKTSEKKVKNKTVAEQRPESCPVSKAKK-DKQPDVFEFLERQTMLLRPGGKWYDMEYSG-------------EYSLEPQP---PDVVSKYKALAQKLYEHEVSLFKSKTN------NQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHTLQFVETLMSLVKKKGSKQQCLMALDTFKELLITDLLPDSRKLRVFSQH--PFHKLEEMSSGNKDSRDRRLILWYYEHQLKHLVAEFVQVLETLSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVINKLGDPQNRIATKASHLLEVLLRKHPNMKGVVCGEIERLLFRSNISPKAQYYAICFLNQMVLSHEESELANKLITLYFCFFRTCIKKKD---------------------------------------------IESKMLSAILTGVNRAYPYSQIGDDK-----VREQVDTLFKVLHVVNFNTSVQALMLLFQVMNSQQTISDRYYTALYRKMLDPGLTTC--SKQAMFLNLIYKSLKADIM-LRRVKAFVKRLLQVTCTQMPP-FICGALYLVSEILKAKPDLRSQLDDHPESD-EENFVDVGDDSDDEKFTDADKGTATDAVKEVESKET----EPESSAEAEKPKA----ASWVHFDNLKGGKQIKTYDPFSRNPLFCGAENTTLWELKKLSEHFHPSVALFAKTILEGNCIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTDSVVMQPKRKHFMKNVRDLA---------VNSKEFLAKEESQIPVDEVFFYRYYKKVAVVKDKQKRSADEES------IEDIDDEEFENMIDTFEDDNCFP-------------------PGKDDIDFASNMKK-TKGAKAD--LEDSESSDGELGDLDDDEVSLGSMNDEDF-EIDEDGGTFMDVSDDESEDAPEFADANPKANTK-------------------KSKRKSEDDFDFAGSFQGQKKKKKSFNDSSLFVSAEEFGHLLDENMGSKFDTIGMNAMANRDNASFKQLKWEAERDDWLHNRDVKSIIKKKKNFRKKM-KAPQKPKRQRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03701-1", "uniprot_id": "CEBPZ_HUMAN", "id": "Q03701-1", "name": "CCAAT/enhancer-binding protein zeta", "aln": "---------------------------MAAVKEPLEFHAKRPWRPEEAVEDPDEEDEDNTSEAENGFSLEEVLRLGGTKQDYLMLATLDENEEVIDGGKKGAIDDLQQ------GELEAFIQNLNLAKYTKAS---------------LVEEDEPAEKENSSKKEVKIPKINNKNTAESQRTSVNKVKNKNRPEPHSDENGSTTPKVKK-DKQ-NIFEFFERQTLLLRPGGKWYDLEYSN-------------EYSLKPQP---QDVVSKYKTLAQKLYQHEINLFKSKTN------SQKGASSTWMKAIVSSGTLGDRMAAMILLIQDDAVHTLQFVETLVNLVKKKGSKQQCLMALDTFKELLITDLLPDNRKLRIFSQR--PFDKLEQLSSGNKDSRDRRLILWYFEHQLKHLVAEFVQVLETLSHDTLVTTKTRALTVAHELLCNKPEEEKALLVQVVNKLGDPQNRIATKASHLLETLLCKHPNMKGVVSGEVERLLFRSNISSKAQYYAICFLNQMALSHEESELANKLITVYFCFFRTCVKKKD---------------------------------------------VESKMLSALLTGVNRAYPYSQTGDDK-----VREQIDTLFKVLHIVNFNTSVQALMLLFQVMNSQQTISDRYYTALYRKMLDPGLMTC--SKQAMFLNLVYKSLKADIV-LRRVKAFVKRLLQVTCQQMPP-FICGALYLVSEILKAKPGLRSQLDDHPESDDEENFIDANDDEDMEKFTDADKET--EIVKKLETEET----VPETDVETKKPEV----ASWVHFDNLKGGKQLNKYDPFSRNPLFCGAENTSLWELKKLSVHFHPSVALFAKTILQGNYIQYSGDPLQDFTLMRFLDRFVYRNPKPHKGKENTDSVVMQPKRKHFIKDIRHLP---------VNSKEFLAKEESQIPVDEVFFHRYYKKVAVK-EKQKRDADEES------IEDVDDEEFEELIDTFEDDNCFS-------------------SGKDDMDFAGNVKKRTKGAKDNTLDEDSEGSDDELGNLDDDEVSLGSMDDEEFAEVDEDGGTFMDVLDDESESVPEL-EVHSKVSTK-------------------KSKRKGTDDFDFAGSFQGPRKKKRNLNDSSLFVSAEEFGHLLDENMGSKFDNIGMNAMANKDNASLKQLRWEAERDDWLHNRDAKSIIKKKKHFKKKRIKTTQKTKKQRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12176-1", "uniprot_id": "MAK21_YEAST", "id": "Q12176-1", "name": "Ribosome biogenesis protein MAK21", "aln": "----------------MSENNGNPLDLSSLRNKISSKLRDNNSKKAKKTHKGKDVKASSNSKKVNEDIRREALALGASEEDLKLIQGLSDDDDAKSEQEFDAVADEDADDKGFKNDLQNFMKNVGFDQHKLED---------------VDDDD--IEEESTSSKESKIPAQEKEHAQSNIASSTIEKTSQESIDNGSEQEENTVEEANLSSDQEPESESAEKEKKEEKDGGLITQTTIISSDKLIIPYDKPWYEIPLDPQVGQNDDVEELSKEQIEKLFERGKQTLEADNQTYYEEFTKDSSQAKFMSQILSDGTLNDKISAVTLLIQDSPLHNTKSLETLVSYCGKK-SRNSALQSLNALKDLFLNGLLP-NRKLRYFKNQ--PGLSMMLN--------KKTLAIFYFEDYLKKLFFRVLEVLEVLSHDPIIHVRLQILNHVFDLLTNQPEQEFNLLRLGVNKIGDIDSKVSSKASYLLLKLEQAHPNMKSIVIDAIVDIALRPNADYHTTYYSVITLNQTILKRSEDSVANKLVKTYFTLFEKFLINTDKDNTNGVVKSNSKSYEEKRKKNFKKGKHGGKSVKIEKTENEVLDEKNSKLFSALLTGINRAFPFAQIPASV-----YEVHMETLFKITHSSNFNTSIQALVLINQVTVKAKLNSDRYYRTLYESLFDPRLVNS--SKQGIYLNLLYKSLKQDALNVERVEAFVKRILQVCSHWLNVGTITGFFFLLIQLAKTVPQIKNLLTNTPVDY------------------------------EYESDAE----EEQGDKDIKR----------------------KEYDGRKRDPKFANAEKSSLWEINNFINHFHPTVKTYANAYVTGETEQIAKPDLGLFTLSHFLDRFVYRSAKQTNTARGTSIMQPLFSGSRVNDSVLVKASDIMHDQGPVNTEDWLTKKVEDIKPEDKFFYQYFTTKKTADGKGKKSNKASN------FDSDDE------MDENEIWSALV-------------------KSRPDVEDDSDDSE-LDFAEDDFSDSTSDDEPKLDAIDDEDAKSEGSQESDQEEGLDEDIFYSFDGEQDNSDKKRSFAESSEEDESS-------------------EEEKEEEENKEVSAKRAKKKQRKNMLKSLPVFASADDYAQYLDQDSD---------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTE6-1", "uniprot_id": "NOC1L_DROME", "id": "Q9VTE6-1", "name": "Nucleolar complex protein 1", "aln": "MPAAVATGVQFGGPPKNKKIVFDDSGEAVVKQNKKEHPQRPKFEGKEQVKKPQKIKFGEDGKAKGAKSFNKNHQKPDFANKPQRIKFGDDGEQVASKSFNQNHKNGPKPQKIKFGEDREAVHQKPFNKNNHKHNGQKSDFANKPQKIKFTDDGEDEVTANSSNTKTEPTKKSQKIKFGDDGESKENFKKPQRIKFDEDGAGKNVSDSDGDSDEELGDSISKKHNKYQSKIDEDEESQKK--------------WYHVHPDYPSTDEVLDMKENDQLELYNLCKNSFEAEKITFN---KRNPSDARWLQTALHKGTAKDRANAGALLVTSNPLGNLEALSTLIGFCKIS--NKASNDVIAVLTDLWQEVLLPPNRKLLAVHTRGADWKKLKKDENLRNEQKRRIYAYWHFESELKDQYHEFLKNVMQGLQTGQEHNKNSSIVSAARLLAYAPEKEQLLLTMLVNKLGDPIAKIASKALHHLSEVAQKHPNMCGVIVAEAEKLLFRNNISERAQHFALCFLSSIAPS-GRPEVCTKLVNICFALFKVLVQKGA---------------------------------------------VNNRTMQAILRCLQKAIVEAKPAKDSNGELLTKEMQDTIYRLVHLADIRVAVQTLGLLLQLVAVKTEKSDRFYNALYVKLLDLNLINVGSKTAAHLLHIVHRAIHIDNH-VARAQAFVKRLLQLTLYAPPH-IAAGCLIVIHKLLRMRRELIGGTGASEEVE-EGSKVVLPISADLDKFGSDDEEVYEDVKDEADDTKDSNPLEEKADNDVKSSASSWHHARVAATEAKVRDIDSCKYDPYHRVPAFAGAAYALRHELLLLRQHYHPTVQVFAEQILQQSRIDYYGDPLRDFGLPHFLERFAFKNPKKLEASQAAENATVAHKR-YMAHGARGRPVKSLTKANCTEDEMFIFNFLEHKRRQAEIVAQNKKQKEIKKDAAEEGDDGEAGEEYLKEGEVDDDEFEAYLDGYFGKKFKEGVDEEQDEEELNFLQELGGEIKKDKSKDKKKKKQSDKAEDEMDDIDDDWGDDDLAEDEDDEIEGEDQSDDETGSIDLQPLDDDDDDDDDDDDEGSISEGGPGDSDSSDAPESPDEEDDDDEDAPPRSKKSRKDSTDMVGGRSFAKTLKQSHDMSSLFAAADDFSSLLEETAKVKGQGT-SNAVFNKDKSSDKQLKWEENRRSNSKSYKGKKFAGKPAAKGGRPQKAGKKRKH---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 107, "similar_positions": 329, "identity": "8.58%" }, { "cls_id": "homologset.agr.SGD:S000002469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V0-1", "uniprot_id": "D4A9V0_RAT", "id": "D4A9V0-1", "name": "serine C-palmitoyltransferase", "aln": "-----------------------------------------------------------MANPRDSAVTNGTLRNPKTQPGKRQSTDCVKNGISK--EAQQNRKAEEDDKLVFKP-YPEPPLYVFVFTYMGYGIGMLFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYTRNLYMRIRDSWSHTVCSVPVPNFDIMEKVTDDYNWTFRHTGKVIKNVINMASYNYLGLASKYNESMEKVKDTIEKYGVGVASTRNEMGSLDIHNELEDLMAKFLNVEAVMVFGMGFATNSTNIPIFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNIQNLEKLLREAIIRGQPRTG-RAWKKILILVEGVYSMEGSIVNLPQIVALKKKYKAYLYMDEAHSIGCTGTMGQGIRELFGLAPEDIDIYMGTFTKSFAASGGYIAGKKEIVDYVRVQSHSATYATSMSPVVAAQIIRSLKIMMGYEGNFGGVQRIQQLRENIKYFRRRLIEMGFIIYGNDYSPVVPVLLYMPAKVSAFGRLLLKKKIAVVVVGFPATSLPEGRARFSLSSAHTREMLDTVLEVVDKIGDLLNVKYFPYK--KSGRAVLYNKENFDNEASFEEKSSEPEA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG54-1", "uniprot_id": "SPTC3_MOUSE", "id": "Q8BG54-1", "name": "Serine palmitoyltransferase 3", "aln": "-----------------------------------------------------------MANLNDSAVTNGTLHNPKTQQGKRQSTGCVKNGISK--EAQQNRKAYAEDKPVFEP-YQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTG-RAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKYFPLK--KSGRAILYNKEGFDNEASFEEMHSEPEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUV7-1", "uniprot_id": "SPTC3_HUMAN", "id": "Q9NUV7-1", "name": "Serine palmitoyltransferase 3", "aln": "-----------------------------------------------------------MANPGGGAVCNGKLHNHKKQSNGSQSRNCTKNGIVK--EAQQNGKPHFYDKLIVES-FEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTR-RAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHK--KSARPELYDETSFELED------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9N3-1", "uniprot_id": "A0A8M9Q9N3_DANRE", "id": "A0A8M9Q9N3-1", "name": "serine C-palmitoyltransferase", "aln": "-----------------------------------------------------------MIRTEELHSCNGTLKSRSGQ--KQTENYTLKNGYHKNEKVQKNGNGFHQPRVRGEDSFEEAPMYVAVLTYMGYGIVILFGYFRDFLRAVGLEKCHQAQEREEQKDFVPLYQDFENFYKRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRLTGRTIENVINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKEAICSGQPRTH-RSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSPPVVEQIIRAIKCIMGVDGTTEGQRRVRQLAENTHYFRSRLKEMGFIIYGNKDSPVIPLLLYQPGKVGAFSRAMLKRKIGVVVVGFPATTITEARARFCVSAAHTRDMLNKVLQSLDELGDYIRVKFSRHR--RPYRPELYNVTNFGLDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97363-1", "uniprot_id": "SPTC2_MOUSE", "id": "P97363-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRS--STATVAAAGQIHHVTENGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRL-VPLLDRPFDETTYEETED-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B7D2-1", "uniprot_id": "SPTC2_RAT", "id": "Q3B7D2-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRS--STATIAAAGQIHHITENGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRP-LPLLDRPFDETTYEETED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15270-1", "uniprot_id": "SPTC2_HUMAN", "id": "O15270-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRL-VPLLDRPFDETTYEETED-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5Y9-1", "uniprot_id": "A0A8M1N5Y9_DANRE", "id": "A0A8M1N5Y9-1", "name": "serine C-palmitoyltransferase", "aln": "------------------------------------------------------MTESAGTKTEDCHAANG-VKPG--RNGMVKNHHHHLQYQKQEKVYHAACNGELYSRPFIES-FEETPMLVAVLTYMGYGILTIFGYLRDFMREWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDSWNRPICSVPGAKFDLVERSSNDYNWTFEYTGRVVKDVINLGSYNYLGFAENTGSCATAAGEVTVKFGVGVASTRQEMGNLDRHEKLEKLVASFLRVESAMAFGMGFATNSMNIPALAGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTH-RPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPGGRGVVEYFGLDPRDVDIMMGTFTKSFGAAGGYIGGRKDLIDYLRTHSHSAVYASSMSAPVVEQIITSMKCIMGEDGTTIGRSRIQRLAENTVYFRRRLREMGFIIYGNNDSPVVPMMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCISAAHSKEMLDRALDVISEVGDLLQLKYSRHKV-LPSLDRPFDETTYEENEE-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3F2-1", "uniprot_id": "Q9V3F2_DROME", "id": "Q9V3F2-1", "name": "serine C-palmitoyltransferase", "aln": "MGNFDGDSGTVFEQSYATTNGNGKVPNGNGAADLSAPEKQELLRKFSAPAYTEIRTRRCQPKPANDAQSPSSINYHPEKKSIPNGHASILDQESK--PNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVP-----KVATEK-GRDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRKP--RDPNPVIY---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40970-1", "uniprot_id": "LCB2_YEAST", "id": "P40970-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------------MSTPANYTRVPLCEPEELPDDIQKENEYGTLD-----SPGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQK--NKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSG-AVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTN-RPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :**:.: : ::*:..::: : : :.. .. :. **.** * : *: * :.:. . * . :: :.: . * :* :*:.***:**:* . . . ..* ::* . : * * * :: * .: :.**:.**: : : . .*::*** **:*: * ****:. : ***.: .**::::: : *:* . :.*.*::* .**::****:: .*.::: ******.**::*****:*. *. *:*: : *.: *.::*: ********..:***:.. : ::* :* . : *: ::.. : * : ::: * * :::: * *:* * .:*.* ** :.*:*:::* .*: *. * : :.*..* ..:***.: *.* **.:*:: ::: :: * :.::.* : :* : ", "identical_positions": 124, "similar_positions": 183, "identity": "19.71%" }, { "cls_id": "homologset.agr.SGD:S000002470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63228-1", "uniprot_id": "GMFB_RAT", "id": "Q63228-1", "name": "Glia maturation factor beta", "aln": "MSESLVVCDVAEDLVEKLRKFRFRKETHNAAIIMKIDKDKRLVVLDEELEG-----VSPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPLGCK-PEQQMMYAGSKNKLVQTAELTKVFEIRN--TEDLTEEWLREKLGFFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQI3-1", "uniprot_id": "GMFB_MOUSE", "id": "Q9CQI3-1", "name": "Glia maturation factor beta", "aln": "MSESLVVCDVAEDLVEKLRKFRFRKETHNAAIIMKIDKDERLVVLDEELEG-----VSPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNKLVQTAELTKVFEIRN--TEDLTEEWLREKLGFFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60983-1", "uniprot_id": "GMFB_HUMAN", "id": "P60983-1", "name": "Glia maturation factor beta", "aln": "MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEG-----ISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNKLVQTAELTKVFEIRN--TEDLTEEWLREKLGFFH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERL7-1", "uniprot_id": "GMFG_MOUSE", "id": "Q9ERL7-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCEVDPELKETLRKFRFRKETNNAAIIMKVDKDRQMVVLEDELQN-----ISPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQTAELTKVFEIRT--TDDLTETWLKEKLAFFR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80T18-1", "uniprot_id": "GMFG_RAT", "id": "Q80T18-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCDVDPELKETLRKFRFRKETNNAAIIMKVDKDRQMVVLEDEFQN-----VSPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQIAELTKVFEIRT--TDDLNETWLKEKLAFFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60234-1", "uniprot_id": "GMFG_HUMAN", "id": "O60234-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQN-----ISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQTAELTKVFEIRT--TDDLTEAWLQEKLSFFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJL6-1", "uniprot_id": "GMF_DROME", "id": "Q9VJL6-1", "name": "Glia maturation factor", "aln": "MSDNQ-ICDISNEVLEELKKFRFSKSKNNAALILKVDREKQTVVLDEFIDD-----ISVDELQDTLPGHQPRYVIYTYKMVHDDQRISYPMCFIFYTPRDSQ-IELQMMYACTKSALQREVDLTRVYEIRE--LDELTEEWLKAKLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12156-1", "uniprot_id": "AIM7_YEAST", "id": "Q12156-1", "name": "Protein AIM7", "aln": "MSNLYKIGTETRNKIKKFRTSTARTDSIKALSIKIEPKPSYEIIVDEDEQEELDEIEDLSELAEILPDNSPRFVLTAYPTTTKDGFKQTPLVLVYWKPMTVVSQEWKMLYAGALEMIREECGTFKLIEVSSGLEDDSDVEELREQLENC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : : : ::. ... :* * : ::::: : . .** ** ..**::: :* .* . *: ::: .* * :*:** : . : . :: *: :: *: :* ", "identical_positions": 21, "similar_positions": 46, "identity": "14.0%" }, { "cls_id": "homologset.agr.SGD:S000002471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62277-1", "uniprot_id": "RS13_HUMAN", "id": "P62277-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62301-1", "uniprot_id": "RS13_MOUSE", "id": "P62301-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62278-1", "uniprot_id": "RS13_RAT", "id": "P62278-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03334-1", "uniprot_id": "RS13_DROME", "id": "Q03334-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGISQSALPYRRTVPSWLKLNADDVKEQIKKLGKKGLTPSKIGIILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHMIKKAVAIRKHLERNRKDKDGKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05756-1", "uniprot_id": "RS13_YEAST", "id": "P05756-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.***:*.**:** *..*:*:**.::.* *** * .:******:**::***:***:*.*.:.****:**:** ** *::*****::*****::************.******:***********:* **********:****** ", "identical_positions": 106, "similar_positions": 36, "identity": "70.2%" }, { "cls_id": "homologset.agr.SGD:S000002473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0E6-1", "uniprot_id": "RPAP2_RAT", "id": "Q5I0E6-1", "name": "RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPYSLGPSARASSTHR-VATGTKQTSALKRRDASKRQAELEAALQRKVESERRAVRLVEQLLEENITEEFLKECGMFITPAHYSDVVDERAIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYKASKFFEAQIPKTPVWVREEERPPEFQLLKKGQSGCSGEVVQFFRDAVTAADVDAYGAFDAQCEPASSSTWSERASDERASDEEGPGFVSSLLP--------GNRPKAVGTKPQPHRQSSTVKKKAAQKMTSKHG--EQTVSEVTEQLSNCRLDS--QEKVATCKLPAKKENTQISSPGPLCDRLNTSTVSENKHSVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVQVRPEVAKANLLRVLKDTLTEWKTDETLKFLYGQDHGSVCLQPSAASGPDEELDEDDISC----------QAQNTLDETLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDSTKSQDSKENELQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLVQTFRLSNRNIIHKPVEWTLIAVVLLSLLTPILGIQKHSPKNVVFTQFIATLLTELHLKCEDLENLAMIFRTSC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC34-1", "uniprot_id": "RPAP2_MOUSE", "id": "Q8VC34-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPCSLGPSTRASSTHR-DATGTKQTRALKRGDASKRQAELEAAIQRKVEFERKAVRIVEQLLEENITEEFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVWVREEERPPDFQLLKKGQSGSSGEVVQFFRDAVTAADVDGSGALEAQCDPASSSSWSERASD-----EEEQGFVSSLLP--------GNRPKAVDTRPQPHTKSSIMRKKAAQNVDSKEG--EQTVSEVTEQLDNCRLDS--QEKVATCKRPLKKESTQISSPGPLCDRFNTSAISEHKHGVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVHVRPEVAKANLLRVLSDTLTEWKTEETLKFLYGQNHDSVCLKPSSASEPDEELDEDDISCDPGSCGPALSQAQNTLDATLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDTTKSQDSKESVLQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLIQTFRLSNRNIIHKPVEWTLIAVVLLLLLTPILGIQKHSPKNVVFTQFIATLLTELHLKFEDLEKLTMIFRTSC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXW5-1", "uniprot_id": "RPAP2_HUMAN", "id": "Q8IXW5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2", "aln": "MADFAGPSSAGRKAGAPRCSR-KAAGTKQTSTLKQEDASKRKAELEAAVRKKIEFERKALHIVEQLLEENITEEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITERKSFCSNFCYQASKFFEAQIPKTPVWVREEERHPDFQLLKEEQSGHSGEEVQLCSKAIKTSDIDNPSHFEKQYESSSSSTHSDSSSD------NEQDFVSSILP--------GNRPNSTNIRPQLHQKS-IMKKKAGHKANSKHKDKEQTVVDVTEQLGDCKLDS--QEKDATCELPLQKVNTQSSSNSTLPERLKASENSESEYSRSEITLVGISKKSAEHFKRKFAKSNQVSRSVSSSVQVCPEVGKRNLLKVLKETLIEWKTEETLRFLYGQNYASVCLKP-EASLVKEELDEDDIISDPDSHFPAWRESQNSLDESLPFRGSGTAIKPLPSYENLKKETEKLNLRIREFYRGRYVLGEETTKSQDSEE-------HDSTFPLIDSSSQNQIRKRIVLEKLSKVLPGLLVPLQITLGDIYTQLKNLVRTFRLTNRNIIHKPAEWTLIAMVLLSLLTPILGIQKHSQEGMVFTRFLDTLLEELHLKNEDLESLTIIFRTSCLPE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYY5-1", "uniprot_id": "RPAP2_DROME", "id": "A8DYY5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "aln": "--------------------------------MTTEKGEQLRQQLIAAVVKKRAAIARAHEIVVRLLEPGIPEPEFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITERKKFCSGYCFKASEYIKSQVPTSPLWLRDRETRPSFQLLPRNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYH6-1", "uniprot_id": "RPAP2_DANRE", "id": "B0UYH6-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase rpap2", "aln": "-------MDAGEVTRKSRPSKSKKKGGKGTQAISAEDEAKRREAVKEQLRQKLELERKARQVVERLLEDSVTEEFLMDCAWHITPANYKDTVEERSIAKLCGYPMCPNKLTNVPTQQYKISTKTNKVYDITERKCFCSNFCYKASKSFELQISKIPLWLRKEESPPEIKLMKQGDGGSSGQEIKLIDKPITEADIDNP----IEDIPESNKDLIQGENG-----DIEQDFVSSVVSNQHKQVHWGKLPKRDEVSEDAAEYSHSEHEQRINGENKDESESSQTPQPQKDTTDHPALEKNASEIEGTLELLNQDKSTQQEGENTSSSQP-ESDISVPVAGDLNITQVGMSKRSAAGLKG-LLKDHHKAKTASTAISQC-------LLERLRQAFIEWRTKETMIFLYGPDYASGMQLSTAGAWEEEQLDED-------------DLDEAEVGVRSAEGGPSRTSAPVPDVETLRKETEMLELRVREFYKGVCVLPEEVETAAVKETEHTQDSGKDPPLPLVDSHAQHQIQKRIVVEKLSHSLRDIVGPLRLTMSDVINDVNNLVRTFRFTNTNIIHKSPEWTLIAVVLLSVLTEVSPLLRESLASVSSLEYISCFMKELKLEDKDLHNLVLLFKPCVPIQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12378-1", "uniprot_id": "RTR2_YEAST", "id": "Q12378-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR2", "aln": "------------------------MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCE--NEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHS------------MYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVP----------------------------------------------------------------------------------------IDTVKSLITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . :: . : * : : * * * :: * *:****:* . ..: : * : :*..: :.* : *:. *: * .. : ", "identical_positions": 17, "similar_positions": 34, "identity": "2.66%" }, { "cls_id": "homologset.agr.SGD:S000002475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AS17-1", "uniprot_id": "A0A8I6AS17_RAT", "id": "A0A8I6AS17-1", "name": "", "aln": "-----------MGITVLDGRGREDVGWWRSWLQQSYQAVKEKSTEALEFMKRDLTEFTQVVQHDTACTIAATASVVKERLATE-GSSGATEKVKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPP------------ELFDAWLSRFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRADQS-ISEEPGWEEEEEE--LERIVP-SPKEAKLPQETKTSTAPENEPAPQSPCEE---IPVEAPA-EATPSESSESISLATQIANPAAAPQPPELPKDLSQKLLEASLEEQSLAEDAGETGPPPPVTSKPLTPAGRASGLEPRPPARVETLREEVPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVEASGELEDVEWEDWE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y55-1", "uniprot_id": "BSDC1_MOUSE", "id": "Q80Y55-1", "name": "BSD domain-containing protein 1", "aln": "---------------MAEG---EDVGWWRSWLQQSYQAVKEKSTEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATE-GSSGATEKVKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPP------------ELFDAWLSEFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRADQS-ISEEPGWEEEEEE--LEGIVP-SPKEAKIPKETKTTTSPEDEPAPQSPCEE---TPVEPPA-EATPSESSESISLVTQVANPAAAPEAPELPKDLSQKLFEASLEEQSLAEDEGETGPPPPPPSKPLTPAGRASGPEPRPPARVETLREEVPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NW68-1", "uniprot_id": "BSDC1_HUMAN", "id": "Q9NW68-1", "name": "BSD domain-containing protein 1", "aln": "---------------MAEG---EDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATE-GSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPP------------ELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQS-ISEEPGWEEEEEE--LMGISPISPKEAKVP-VAKISTFPEGEPGPQSPCEENLVTSVEPPA-EVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIJ3-1", "uniprot_id": "BSDC1_DANRE", "id": "A2BIJ3-1", "name": "BSD domain-containing protein 1", "aln": "---------------MADG----EGGWWGGWLTQSFQSVKDKSAEAYEFIKRDLTEFSSVVQHDTACSVVATANAIKSKLAVE-GSSETTEKVKKGITNILGVITDTLAPPPDKTIDCDVITLVATPTGTTEVYDSGKARLYSLQADPATYCNEPDGPP------------QQFDSWLSTFSLEERKAEISELLVSSPAIRALYTKMVPAAVAHAEFWQRYFYKVFQLEQEEARRVALKQRAEQTDHSESLGWEEEDEEGEFLGATSLSRLDFTPPVEESRVPAVTVADTPESSSPPQAVASLSNVASDVTPSVSSDSVSFPTQIENQAES---------VTIRVTQPSPAADELSQKLSDTG-------------LQETFPEERPAPREETAREDMAQDLRVFELNSDSGKSTPSNNGKKGSSTDVSEDWEKDFDLDMTEEEVQMALSKVDATEELEDEDWENWE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54858-1", "uniprot_id": "DOS2_YEAST", "id": "P54858-1", "name": "Protein DOS2", "aln": "MEFFYEEQVACIEDDKISNSHTKETGSTENTENNELQSRDDKTNEAFQKLEEEVNKRYEKTTSAFKKLVIEKDDGIEINLPISNETTETAQKYLKKLDENIHSVESLAQSYWSKMKTKNFWSGFSSFDNAAE-NDSNDKDENSKENEIAVGGNRTEAELRTLSKDKSVYLDNKMDLQLDPFDVDEKTEEICSILQGDKDISKLMNDIVPHKISYKDFWHIYFLQRNKILDKESKRKEILSKKEKETEEKEVEWDDEEEE--------------------------------------------------------------------------------------------------------------------------------------------------EDDDKVEAVADNKSKGETKVAVSQE-------GLKDVSDHVGLANKDESKDDDDD--DDWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : * . :. *: .:*: ** : ::.::.: . . : . . :: .*. . :: :::* * : : : : . . .* :. : ..: .::* *. . * : : *. *..:. : :* *. * ::*:. **..:* .. * * ..:** ::: :**: ** : :: :::::* : .: :: .:. *::*:** :.*. ::...*:.* :.. :*:: .:.: . ::.*:: : : : :* ::**", "identical_positions": 42, "similar_positions": 129, "identity": "9.01%" }, { "cls_id": "homologset.agr.SGD:S000002476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88623-3", "uniprot_id": "UBP2_MOUSE", "id": "O88623-3", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPR------------PRTYGPS----------------SILDCDRGRPLLRSDIIGSSKRSESQTRGNERPSGSGLNGGSGFS-YGVSSNSLSYLPMNARDQGVTLSQ-------------KKSNSQSDLARDFSSLRTSDGYRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLEN-----------------------------YGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKSAQG-------LAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHT--ALMEEFAKLIQTIWTSSPND----VVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KASPETLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTS---------KLTTFVN------FPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVTPMS-SSQVRTSDAYLLFYELASPPSRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U349-1", "uniprot_id": "UBP2_RAT", "id": "Q5U349-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKSGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPR------------PRTYGPS----------------SILDCDRGRPLLRSDITGGSKRSESQTRGNERPSGSGLNGGSGFP-YGVTSNSLSYLPMNARDQGVTLGQ-------------KKSNSQSDLARDFSSLRTSDSYRTSDGYRASDGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLEN-----------------------------YGRKGSAPQVLTQAPP-SRVPEVLSPTYRPSGRYTLWEKNKGQASGPSRSTSPGRDTMNSKSAQG-------LAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHT--ALMEEFAKLIQTIWTSSPND----VVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KPSPESLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTS---------KLTTFVN------FPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVTPMS-SSQVRTSDAYLLFYELASPPSRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75604-1", "uniprot_id": "UBP2_HUMAN", "id": "O75604-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFLTR------------PRTYGPS----------------SLLDYDRGRPLLRPDITGGGKRAESQTRGTERPLGSGLSGGSGFP-YGVTNNCLSYLPINAYDQGVTLTQ-------------KLD-SQSDLARDFSSLRTSDSYR------------IDPRNLGRSPMLARTRKELCTLQGLYQTASCPEYLVDYLEN-----------------------------YGRKGSASQVPSQAPP-SRVPEIISPTYRPIGRYTLWETGKGQAPGPSRSSSPGRDGMNSKSAQG-------LAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHT--ALVEEFAKLIQTIWTSSPND----VVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRP------KSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTS---------KLTTFVN------FPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMS-SSQVRTSDAYLLFYELASPPSRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLD6-1", "uniprot_id": "A0A8M9QLD6_DANRE", "id": "A0A8M9QLD6-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRVSSTAKRYAGSS-YT-SHYSS--YGSSLTPSLGSYERDKLPYKSSSSGFSSSSSSYLSSS----------ASRSRNYS----------------SSSEPDRGRPIPRTDLLGG-RRSESLSRTPVKGYGSGLNGGSGYSSYSYTPAPSSYLSSSPVSSSISLSR-------------RKSVSQSDLTHDLSAL------------------------------------------GLSETSSGSGLKQSYLS---------------------------------RGSD---VSDSYSSSRSSLGLSRSSTQEGLGSSGLKSSSRFSSSYRSTSPVRESLNSKSAQG-------LVGLRNLGNTCFMNSILQCLSNTQSLRDYCLHNSHRRDLNNNNRTHT--ALMEEFAKLIQTMWTSSSSE----AVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRP------RGNTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCSECGYCSTVFDPFWDLSLPIAKKG-YGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTS---------KLSTFVN------FPMKDLDLREFASDRSSSAVYNLYAVSNHSGTTMGGHYTAYCCNPENGEWYTYNDSRVTPMS-ASQVRSSDAYVLFYERAGL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32571-1", "uniprot_id": "UBP4_YEAST", "id": "P32571-1", "name": "Ubiquitin carboxyl-terminal hydrolase 4", "aln": "MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAKDQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHIIVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKSFIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSASSQMEILLIDIRSRLEFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYTDANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGRQVSSSFPSNNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQSDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGNSLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRFPQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHRVYGV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. :. : . . * *.. . . . : .. . . . : : ...: * : . ...:...* : . : .:*. . . :: : . .*.: : : * :. . .* . :. : : .* . :* . . ... : . *.. : : ..:.. .**.****:*:**.*:**: .*:.* : *. : :.: . : * : **:*:: ::... . :** :** . * .***.*** :*******:::*: .* : ::*. . * ::* : * * *** ** * *.*. *.: **.::** **:**.*:. :::: **:* *** : *: **: * :*. *: . *:::: ::*: *::*****.: :.. .*:.* ** * . . *:**.*: * ** ******* . . * ::*: .*:. ::. .*:**:***. . ", "identical_positions": 122, "similar_positions": 187, "identity": "13.13%" }, { "cls_id": "homologset.agr.SGD:S000002478", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64666-1", "uniprot_id": "SNAT_RAT", "id": "Q64666-1", "name": "Serotonin N-acetyltransferase", "aln": "--MLSIHPLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCP-LHLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESL-TLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCENALVPFYEKFGFQAMGPCAITMGSLTFTELQCSLRCHTFLRRNSGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88816-1", "uniprot_id": "SNAT_MOUSE", "id": "O88816-1", "name": "Serotonin N-acetyltransferase", "aln": "--MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCP-LYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESL-TLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16613-1", "uniprot_id": "SNAT_HUMAN", "id": "Q16613-1", "name": "Serotonin N-acetyltransferase", "aln": "MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCP-LYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESL-TLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12447-1", "uniprot_id": "PAA1_YEAST", "id": "Q12447-1", "name": "Polyamine N-acetyltransferase 1", "aln": "--MASSSSTLPLHMYIRPLIIEDL--KQILNLESQGF----PPNERASEEIISFRLINCPELCSGLFIREIEGKE----------VKKETLIGHIMGTKIPHEYITIESMGKLQVESSNHIGIHSVVIKPEYQKKNLATLLLTDYIQKLSNQEIGNKIVLIAHEPLIPFYERVGFKIIAENTNVAKDKNFAEQKWIDMERELIKEEYDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : * :: .* :. * * : :: ** :*. *. *.: **. .:: *:..*:*: :* : **: .*: ... :* :.:: ::::. ..:** *:::*..* .: .*:..:.*:****:..*: :. : . . .* * : : :::.: . ", "identical_positions": 34, "similar_positions": 78, "identity": "16.27%" }, { "cls_id": "homologset.agr.SGD:S000002481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y119-1", "uniprot_id": "Q9Y119_DROME", "id": "Q9Y119-1", "name": "", "aln": "MPDTEIIVTNAGEPSTKASLIVVSNRLPFVLIRDPKTDELERRASAG--GLVTAVCPVVIKGSG---LWVGWSGIHLKDPN--------------------------EAIPESNPNDQTPTAGLKSEQVVSVNIDS--------KIFDSYYNGCCNKIFWPLFHSMPGRANFGG---EHWHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVWIHDYHLMLAANWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLGCRVDR-------NNLLVEHGGRTVRVRPLPIGIPYERFVNLATTAPKVLKTS-------KMQIILGVDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSR-TDVKEYRELKEEVDQLVGRINGRFTTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEV-----PGVLVISPFAGAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDVSHWMRCFLKAVGALEMDDVGTTIMQPVSVDDFDDYLLKYIGYNHKLALLLDYDGTLAPIAPHPDLATLSPEIKNVLYKLSNHSDVYVAVISGRNVDNVKKMVG--IEGITYAGNHG---LEILHPDGSKFVHPMPMEYEKKVSDLLKALQDSVCRDGAWVENKGALLTFHYRETPNHL----RGAMVDKARSLIEKYGFKATEAHCALEARPPVQWNKGRASIYILRTSFG------VDWNERIK-------IIYVGDDLTDEDAMVALKGMARTFRVTSSD------------------IVKTAADHRLPSTDSVYTLLKWVERHFMGRKARANSLTYRPTKGDGVQMQMSLEVAASANNLEV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31688-1", "uniprot_id": "TPS2_YEAST", "id": "P31688-1", "name": "Trehalose-phosphatase", "aln": "----MTTTAQDNSPKKRQRIINCVTQLPYKIQLGESNDDWKISATTGNSALFSSLEYLQFDSTEYEQHVVGWTGEITRTERNLFTREAKEKPQDLDDDPLYLTKEQINGLTTTLQDHMKSDKEAKTDTTQTAPVTNNVHPVWLLRKNQSRWRNYAEKVIWPTFHYILNPSNEGEQEKNWWYDYVKFNEAYAQKIGEVYRK-----------GDIIWIHDYYLLLLPQLLRMKFNDE--SIIIGYFHHAPWPSNEYFRCLPRRKQILDGLVGANRICFQNESFSRHFVSSCKRLLDATAKKSKNSSNSDQYQVSVYGGDVLVDSLPIGVNTTQILKDAFTKDIDSKVLSIKQAYQNKKIIIGRDRLDSVRGVVQKLRAFETFLAMYPEWRDQVVLIQVSSPTANRNSPQTIRLEQQVNELVNSINSEYGNLNFSPVQHYYMRIPKDVYLSLLRVADLCLITSVRDGMNTTALEYVTVKSHMSNFLCYGNPLILSEFSGSSNVLKDAIVVNPWDSVAVAKSINMALKLDKEEKSNLESKLWK--EVPTIQDWTNKFLSSLKEQASSND--DMERKMTPALNRPVLLENYKQAKRRLFLFDYDGTLTPIVKDPAAAIPSARLYTILQKLCADPHNQIWIISGRDQKFLNKWLGGKLPQLGLSAEHGCFMKDVSCQDWVNLTEKVDMSWQVRVNEVMEEFTTRTP--GSFIERKKVALTWHYRRTVPELGEFHAKELKEKLLSFTDDFDLEVMDGKANIEVR-PRFVNKGEIVKRLVWHQHGKPQDMLKGISEKLPKDEMPDFVLCLGDDFTDEDMFRQLNTIETCWKEKYPDQKNQWGNYGFYPVTVGSASKKTVAKAHLTDPQQVLETLGLLVGDVSLFQSAGTVDLDSRGHVKNSESSLKSKLASKAYVMKRSASYTGAKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: ..*..: :* .:**: : . ..*: : *::* .*.::: : :..: ***:* : . :.:. : :. .. *:: . :. : . : :* :.. .:*::** ** : . :* * : *:***..*: :* : *. .* *:*****:*:* .: :* : ::: . :.:* * *:*. : ** ** .:**:*::*.: : *: :.:. :**..*:* *.. ..: :: *. * * * .****: :::: * * *. : :**:* **** .:*:*::* ***::* **: :::* *:*:* *: : : .*:::*::**. **..: . *::*::: * :.:* :* * * :**:*.:***** .* *:*: : : . *::* *:*:.:::::*:: **:: .*: *: **.: ::*: ::* : :..* . **.:: .: : : :: **: :: :*:******:**. .* * *..: .:* **. ... : :****: . ::* :* : : :.:** :: * ::.. : *.:: :*.:::: : . *:::*.* . **:***.* .* : :* *: :.:.::. :.:. :*.* * ***. :: ..* . .*:: :: :***:**** : *: : :: . .* **.*. :*...:.* * : .. :: .. : .. : .:. ::*:.* :: ", "identical_positions": 193, "similar_positions": 325, "identity": "20.98%" }, { "cls_id": "homologset.agr.SGD:S000002482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJ92-1", "uniprot_id": "PP4C_RAT", "id": "Q5BJ92-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMTCRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60510-1", "uniprot_id": "PP4C_HUMAN", "id": "P60510-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97470-1", "uniprot_id": "PP4C_MOUSE", "id": "P97470-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JRC7-1", "uniprot_id": "PP4CB_DANRE", "id": "A9JRC7-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit B", "aln": "----MGDMSDLDRQIDQLRRCELIKENEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8WGP3-1", "uniprot_id": "PP4CA_DANRE", "id": "A8WGP3-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit A", "aln": "MCVIMGDFTDLDRQIEQLRRCELIKENEVKALCAKAREILVEESNVQSVDSPVTVCGDIHGQFYDLKELFRVGGEVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFFDECHRKYGSATVWRYCTEIFDYLSLSAIVDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDISMICRAHQLVMEGYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----LPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76932-1", "uniprot_id": "PP4C_DROME", "id": "O76932-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MSDYSDLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEYLHRDFVIFEAAPQESRG----IPSKKPQADYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32345-1", "uniprot_id": "PP4C_YEAST", "id": "P32345-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "-------MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: * .*: : * *. * ** :::*:*::*.** **:***:*******::** **. .* * :..*:*:*******:**:*:*****. *:**************:****:****:** ****. ***** *:******.**::..**********.: :*:**:*********:*.*********** *.:******:***. * ** *::.: .*********:* *: ::*****************:*:::: *:::: ****. :.. :*:**. ****", "identical_positions": 182, "similar_positions": 74, "identity": "57.78%" }, { "cls_id": "homologset.agr.SGD:S000002487", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQ35-1", "uniprot_id": "A0A8I6AQ35_RAT", "id": "A0A8I6AQ35-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIVAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDITSKQRITNVPRDD-----ISLRPDMYPCSLCWKDAVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISHRNIKRHKILEIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSLNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5KU39-1", "uniprot_id": "VPS41_MOUSE", "id": "Q5KU39-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDDSGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIIAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKVFDITSKQRISNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQRNIKRHKILDIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSMNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49754-1", "uniprot_id": "VPS41_HUMAN", "id": "P49754-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET-FDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNA---------------ALWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F590-1", "uniprot_id": "VPS41_DANRE", "id": "E7F590-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEVEEQGRKLSEESTDESEEEDTEEEPKLKYERLTNGVTEILQKDAASCMTVHDKFLALGTHFGKVFLLDIQGN-VTQKFEISS-----VKINQISLDESGDHVGICSEDGKVQVFGLYTREGFHEN-FDCPIKVVALHPQFSKSNNKQFVTGGNKLLLYERNWLNRWKTSVLHE--------------GEGNITSVKWRGNLIAWANNVGVKIYDIGSKQRITNVLRDN-----TSLRPDMYPCSLCWKDNTTLIIGWGCSVKICAVKERD-------------------------------PTEMR--DLPSRYVEIVSAFETEFFISGLAPL-ADQLVTLYYVKENSDHMEEEFRTRPRLDIIQPLPE----------------GCEEISSDALTVRNFQENQCRDYRLEHSEGESL--FYIISPKDIVVAKERDQDDHIDWLLEKKKYEEALMAAEISFKNIKRHDVQKIGMAYINHLVEKGDYDTAARKCQKVLGKNM---------------DLWENEVYRFKTIGQLKAISQYLPRGDL-RLRPAIYEMILHDFLKTDYEG-FATLIREWPGELYNNMAIVQAVN----------EHLKKDPTNSILLTTLAELYTYDQRYDRALEIYLRLRHKDVYQLIHKHNLFSSIKDKIVLLMDFDKE-------------------KAVDMLLDNEDKISMDKVVEELKDRP-----ELLHVYLHKLFK-RDHHKGQKYHERQISLYAEFDRPNLLPFLRESMHCPLEKALEICQQRH-FVEETVFLLSRMG--NCRRALQMIMEELANVDKAIEFAKEQDDRELWEDLISYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILHDYNLQILLREGCKKILVADSLSLLQRMHRTQKKGVRVDEENICESCHTPILPSDTAQAFGVVVFHCRHMFHKECLPSPGSIPGIQYCNICSAKRRGPGSGILEMKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PL76-1", "uniprot_id": "VPS41_DROME", "id": "Q7PL76-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAKALP--LISCDSWADSINEE--DVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNLSASERHTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEPDS-KAHIKRFVVGDDKLILYERNLLKKLKPVELCS--------------VEGSVLSICWHGNFIAWASHIGVRVYDLNERCSLGLIKWEVP----PQERLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRN-------------------------------SIEASTGNLPVYIVDPISTFQTTFYVCGLAPLSAKQLVVLGFRKEKSSCFK---ALRPVLCVIEYKMN----------------NSEEICTDSLTLRGFEEYTVNDYSLGGIIEENR--FYIVAPKDIVVASLIETDDRIEWLIKHSKFEEAMELISANGGNVP---VLSVAKLYINHLLALKKYDDAAKLCLRMLGNDK---------------VLWEEEVFKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLYEFLKFDVCG-FLNLIKEWPSHLYDGLAVINAIH----------DNFRKHYAN-QLLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRYELYDVISKLIIPLIQLDRD-------------------CAFEILLDKK-KIKTEIVVHQLEHNQ-----EYLYWYLDSLLK-KDPSN--VFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQEN-FYPEIVYLLGCMGGVEASEALNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPAVVVGK-IKMGQNIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQVSYEQLCSLCHRPVLMAG-THLYCIIRLECGHVYHKPCIQG----ELLKNCNECNLWKLTVGK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38959-1", "uniprot_id": "VPS41_YEAST", "id": "P38959-1", "name": "Vacuolar protein sorting-associated protein 41", "aln": "MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTSPTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRS--------SILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSMLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDLFNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFDWFMERKQYYKAWKIGKYVIGSEER---FSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNSLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPA--LRKSVYDDVLHYFLANDMINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIG--ETKKALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDIEINDDLNGVL----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :. *. :*: : * :** *::: . ::: * :. . .*: :**. * : : : : . : :: .*.:.. * **.: : .: : . * *: :::... : .::* :*. : . * . :* : .: *.:* * .. *: . *: : : : . * : : : : : ::*** .: : : . . . * *: . * . : : ***.: .**: * : : .. : . : : :** .* : ::.::: .** * :. :*:::..* : .. . .*:::*::::.:: :* . . .:. ::* *: .:. . :: : * : : :: :: :* * :*: :*: ** * . * * :* .*:. . : :. ::. * *. ** : : *: * :. . :*: :* . *: :: : . ..::*:::. .*. : . ::. : . ** .::. * :.:: *.**: :** .*****: . ::.*: :*... : * ::* . :* : **.:*:..: : : **:* *: .* :**: :* .:* : . :* . : : : :. . :* **:: : ::::. .*. : .. * : .: ..: : :* .. :: : ", "identical_positions": 112, "similar_positions": 292, "identity": "10.58%" }, { "cls_id": "homologset.agr.SGD:S000002488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A7YY82-1", "uniprot_id": "A7YY82_RAT", "id": "A7YY82-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------MASKQAAAKGKGEKRKRVVLTLKEKIDICSRLERGE--SRKALMQEYNVGMSTLYDIKAHKAQLLSFFASSDSRQALEQRRTLHT-PKLEHLDRVLYEWFLVKRAEGIPVSGPMLIEKAKDFYKQMRLTE-------PCVFSGGWLWRFKARHGIKKLDASSEKQV----------ADPQAAEQFCG-----------FFRSLAAEHGLSPEQVYSADETGLVWRCLPS---STPDDGTVPRFKQGKDRLTVLMCANATGSHRIKPLAIGKGGGPRAFRG-------------------IQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIG--LPEDSKAILLLDHSRAHPQESELVSEN--VFTIFLPSSVTSLLQPTEQGIRRAFMRLFIN--------PPVALQGFP------------------------TRHNVNDAIVNVACAWNAVPSQVFRRAWRKLWPTV--------------------------------------------------------------------------PFTEGSSSGE--EAECCSIKPH-KTFAHILELVKEGPSCSGSRLQDSRVEERLVSGRDMD--EAPAVVAPSQTTGCAEKSEK-----------------------------------------------------------------------------------------------DAGEDEETVWEQAATSFEALVRFAERQPCFSVQEVGQLQALHTVFRRQQQLRQPRVALRAVIKLEALQEHPGVCMATAHSALPCSSTAGDN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60976-1", "uniprot_id": "JERKY_MOUSE", "id": "Q60976-1", "name": "Jerky protein", "aln": "-------------------------------------------------------------------------------------------------------MASKQAAAKGKGEKRKRVVLTLKEKIDICTRLERGE--SRKALMQEYNVGMSTLYDIKAHKAQLLRFFASSDSRQALEQRRTLHT-PKLEHLDRVLYEWFLVKRAEGIPVSGPMLIEKAKDFYKQMRLTE-------PCVFSGGWLWRFKARHGIKKLDASSEKQA----------ADHQAAEQFCG-----------FFRSLAAEHGLSPEQVYSADETGLVWRCLPN---SAPDDGTVPHFKQGKDRLTVLMCANATGSHRIKPLAIGKGGGPRAFRG-------------------IQHLPIAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIG--LPEDSKAILLLDHSRAHSQESELVSEN--VFTIFLPSSVTSLLQPTEQGIRRAFMRLFIN--------PPVAFQGFP------------------------TRHNINDAIVNVARAWNAVPSQVFQRAWRKLWPTV--------------------------------------------------------------------------TFTEGSSSEE--EAECCAIKPH-KTFAHILGLVKEGPTCSGSRLQDSRVEERVVAGRDID--EAPAIVAPSQATRCTKKSEK-----------------------------------------------------------------------------------------------DTGETEEAAWEQAATSFEALVRFAERQPCFSVQEMGQLQALHTVFRRQQQLRQPRVALRAVIKLEALQEHPGVCVATTHPTLPCSSTAGDN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75564-1", "uniprot_id": "JERKY_HUMAN", "id": "O75564-1", "name": "Jerky protein homolog", "aln": "-------------------------------------------------------------------------------------------------------MASKPAAGKSRGEKRKRVVLTLKEKIDICTRLEKGE--SRKALMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNKALEQRRTLHT-PKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTE-------PCVFSGGWLWRFKARHGIKKLDASSEKQS----------ADHQAAEQFCA-----------FFRSLAAEHGLSAEQVYNADETGLFWRCLPN---PTPEGGAVPGPKQGKDRLTVLMCANATGSHRLKPLAIGKCSGPRAFKG-------------------IQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIG--LPEDSKAVLLLDSSRAHPQEAELVSSN--VFTIFLPASVASLVQPMEQGIRRDFMRNFIN--------PPVPLQGPH------------------------ARYNMNDAIFSVACAWNAVPSHVFRRAWRKLWPSV--------------------------------------------------------------------------AFAEGSSSEEELEAECFPVKPHNKSFAHILELVKEGSSCPG-QLRQRQAASWGVAGREAEGGRPPAATSPAEVVWSSEKTPKADQDGRG----------------------------------------------------------------------------------------DPGEGEEVAWEQAAVAFDAVLRFAERQPCFSAQEVGQLRALRAVFRSQQQE---------TVGLEDVVVTSPEELAIPKCCLEASTET-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RRL2-1", "uniprot_id": "JERKL_MOUSE", "id": "B2RRL2-1", "name": "Jerky protein homolog-like", "aln": "-----------------------------------------------------------------------------------------------------------------MSGKRKRVVLTIKDKLDIIKKLEDGG--SSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKP-SMYEELDKAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDG-------DFNPSAGWLTRFKQRHSIREINIRNERLN----------GDETAVEDFCN-----------NFRDFIEQENLQPEQIYNADETGLFWKCLPSRTTVIKGKCTVPGHNLGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTD-----------------TLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKG--LQEK--AVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLHNNLEEGNDLKSFW------------------------KKLTLLDALYEIAMAWNLVKPVTISRAWKQILPAI--------------------------------------------------------------------------EEKEGLDFD-EDISGATVATILQHTKGLENVTPENLEKWLEIDSTEPGYEVLTDS-EIIRRAQGQTDESSENDEERIELIPE----------------------------------------------------------------------------------------------------KHINHTTALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMTNPGQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5M5-1", "uniprot_id": "M0R5M5_RAT", "id": "M0R5M5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MSGKRKRVVLTIKDKLDIIKKLEDGG--SSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKP-SMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDG-------DFNPSAGWLTRFKQRHSIREINIRNERLN----------GDETAVEEFCN-----------HFRDFIEQENLQPEQIYNADETGLFWKCLPSRTAVVKGKCTVPGHNSGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTD-----------------TFNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLKSKG--LQEK--AVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIATMKRNYRAGLLHNNLEEGNDLKSFW------------------------KKLTLLDALYEIAMAWNFVKPVTISRAWKQILPAM--------------------------------------------------------------------------EEKEGLDFDEEDISGATVATILQHTKGLENVTPESLEKWLEIDSTEPGYEVLTDS-EIIRRAQGQTDESSENDEEGIELIPE----------------------------------------------------------------------------------------------------KHINHTTALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMTNPSQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4A0-1", "uniprot_id": "JERKL_HUMAN", "id": "Q9Y4A0-1", "name": "Jerky protein homolog-like", "aln": "-----------------------------------------------------------------------------------------------------------------MSGKRKRVVLTIKDKLDIIKKLEDGG--SSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKP-SMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDG-------DFNPSAGWLTRFKQRHSIREINIRNERLN----------GDETAVEDFCN-----------NFRDFIERENLQPEQIYNADETGLFWKCLPSRISVIKGKCTVPGHKSIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTD-----------------TLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKG--LQEK--AVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNYRAGLLQNNLEEGNDLKSFW------------------------KKLTLLDALYEIAMAWNLVKPVTISRAWKKILPMV--------------------------------------------------------------------------EEKESLDFDVEDISVATVAAILQHTKGLENVTTENLEKWLEVDSTEPGYEVLTDS-EIIRRAQGQADESSENEEEEIELIPE----------------------------------------------------------------------------------------------------KHINHAAALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMTKSSQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VBL1-1", "uniprot_id": "TIGD2_MOUSE", "id": "Q0VBL1-1", "name": "Tigger transposable element-derived protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------MLGKRKRVVLTIKDKLDIIKKLEEGN--SFKKLSVLYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKS-STYEELDRVMIEWFNQQKTDGIPVSGTICAKQARFFFDALGMEG-------DFNASSGWLTRFKQRHGIPKAAGKGTKLK----------GDETAASEFCG-----------NFQEFVERENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTD-----------------LSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKG--LREK--AVLLLDFPAAHPAEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGNDPKTFW------------------------KNLTVLDAIYEASRAWNQIRSNTITRAWKKLFPGN--------------------------------------------------------------------------EENPSVSIDEGAILAANLATVLQNTEDCEHVNIENIEQWFDSRSSGSNCQVLADIVGAADRAKVTEQK-PSRKTRKAELNPE----------------------------------------------------------------------------------------------------KHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQNKSHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVC4-1", "uniprot_id": "F1LVC4_RAT", "id": "F1LVC4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MLGKRKRVVLTIKDKLDIIKKLEEGN--SFKKLSVLYGIGESTVRDIKKNKERIINYANNSDPTSGVSKRKSMKS-STYEELDRVMIEWFNQQKTNGIPVSGTICAKQARFFFDALGMEG-------DFNASSGWLTRFKQRHGIPKAAGKGTKLK----------GDETAASEFCG-----------NFQEFVKRENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGLHKLNLCVVGKAKRPRAFKGTD-----------------LSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKG--LREK--AVLLLDFPAAHPAEELLNSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGNDPKLFW------------------------KNLTVLDAIYEASRAWNQIRSSTITRAWRKLFPGN--------------------------------------------------------------------------EENPSVSIDEGAILAANLATVLQNTEDCEHVNIENIGQWFDSRSSGSNCQVLADLVGAADRAKAGEQKQPSRKTRKAELNPE----------------------------------------------------------------------------------------------------KHISHRAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQTKSHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4W5G0-1", "uniprot_id": "TIGD2_HUMAN", "id": "Q4W5G0-1", "name": "Tigger transposable element-derived protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------MLGKRKRVVLTIKDKLDIIKKLEEGI--SFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKS-STYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEG-------DFNASSGWLTRFKQRHGIPKAAGKGTKLK----------GDETAAREFCG-----------SFQEFVEKENLQPEQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTD-----------------LSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQVQKHLKSKG--LLEK--AVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGNDPKIFW------------------------KNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGN--------------------------------------------------------------------------EENSGMNIDEGAILAANLATVLQNTEECEHVDIENIDQWFDSRSSDSSCQVLTDSESAEDQTKAAEQK-PSSKSRKTELNPE----------------------------------------------------------------------------------------------------KHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRKKQKIQNNKNH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUZ3-1", "uniprot_id": "TIGD4_MOUSE", "id": "Q8BUZ3-1", "name": "Tigger transposable element-derived protein 4", "aln": "------------------------------------------------------------------------------------------------------MAEASVDIGTQPVTVKKKKSLSIEEKIDIINAVESGK--KKAEIAAEYGIKKNSLSSIMKNKDKVLEAFES--LRFD-PKRKRLRT-AFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQKLGHN--------DFKCSNGWLDRFKSRYGLVFRAQPVEATG---------ISIDPSTVWYQN-------------VLPYYLNDYHPKNVFNVKETGLLYRMLPTNTFAFKGETCSVG-KLCKDRITLALGTNMDGSEKLPLLIIGKNRAPRCFKG-------------------IKSLPVYYEANRTAWMTAAIFEQWMQKLDEKFQAQKRR-----------VVIFVDSCPAHP---EVKN-LKSIELAFFPSCLSSGFAAMNQGVIKSLKIKYRHCLIKKFLSSVESSKE--------------------------FTFSLLDAVDTLHLCWRAVTPETIVKSYEEAGFRS--------------------------------------------------------------------------PKGENDTANADA---------------AVALDLTAHAVGAGVEFLEGLS--------------IEEYAALDEDLETCEATQ--------------------------------------------------------------------------------------------------KDDAEWAGESKQDETGLYTSDEEEEDSGALEVDLPSPSKKDALSAVGTLKRFLRSHDLNDELHGSLADLENFINALSPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AC64-1", "uniprot_id": "D4AC64_RAT", "id": "D4AC64-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MAEASLDAGTPPVTVKKKKSLSIEEKIDIINAVESGK--KKAEIAAEYGIKKNSLSSIMKNKDKVLEAFES--LRFD-PKRKRLRT-AFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQKLGHN--------DFKCSNGWLDRFKSRYGLVFRAQPVEATG---------VSTDPSAVWYQN-------------VLPYYLNDYHPKNIFNVKETGLLYRMLPTNTFAFKGETCSIG-KLCKDRITLALGTNVDGSEKLPLLIIGKNRAPHCFKG-------------------VKSLPVYYEANRTARMTAVIFEQWMQKLDEKFQAQKRR-----------VVIFVDSLPAHP---EVKN-LKSIELAFFPSCLSSGFAAMNQGVIKSLKIKYRHCLIKKFLSSVESSKE--------------------------FTFSLLDAVDTLHLCWRAIAPETIVKCYEEAGFSS--------------------------------------------------------------------------PRGETDTANAEED--------------AAALDLTAHAVGAGVEFLEGLS--------------IEGYAALDEDLETCEDAP--------------------------------------------------------------------------------------------------KDGAEWDEESKQDVTGFYTSDEEEEDSGALEVDLPLPSTNEALTALGTLKRFLRSHDMNDELHSSLADLENFINTLSPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY51-1", "uniprot_id": "TIGD4_HUMAN", "id": "Q8IY51-1", "name": "Tigger transposable element-derived protein 4", "aln": "------------------------------------------------------------------------------------------------------MAEASVDASTLPVTVKKKKSLSIEEKIDIINAVESGK--KKAEIAAEYGIKKNSLSSIMKNKDKVLEAFES--LRFD-PKRKRLRT-AFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQKLGHN--------DFKCSNGWLDRFKSRYGLVFRAQPVEATG---------VPVDPSTVWYQN-------------VLPYYLNDYHPKNVFNIKETGLLYRMLPTNTFAFKGETCSVG-KLCKDRITLVVGTNMDGSEKLPLLVIGKKRTPHCFKG-------------------LKSLPVCYEANRMAWMTSDVFEQWMRKLDEEFQAQQRR-----------VVIFVESFPAHP---EVKN-LKSIELAFFPSCLSSKCIAMKQGVIKSLKIKYRHCLIKKFLSSVEGSKE--------------------------FTFSLLDAVDTLHLCWRAVTPETIVKSYEEAGFKS--------------------------------------------------------------------------QKGESDITNAEK---------------DTGLDLVADALGAGVEFPEGLS--------------IEEYAALDDDLETCEAAP--------------------------------------------------------------------------------------------------NGDSICTKESKSDETGFYTSDEEDDD-GSPGTELPLPSKSEAITALDTLKKFLRSQDMNDGLQNSLADLENFINSLSPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27790-1", "uniprot_id": "CENPB_MOUSE", "id": "P27790-1", "name": "Major centromere autoantigen B", "aln": "-------------------------------------------------------------------------------------------------------------------MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERK--YGVASTCRKTNKL-SPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD--------DFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPGWHTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPA--RQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQ---------------------GGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRR-----------VLLLAGRLAAQS---LDTSGLRHVQLAFFP---PGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSG------------------------LQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITT---------------------------------------------------------------SFKSEGEEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEE-GGEGEEEGEEE--VEEEGEVD-DSDEEEEE-SSSEGLEAEDWAQGVVEASGGFGGYSVQ----------------------------------------------------------------------EEAQFPTLHFLEGGEDSDSDSDEEEDDEEEDEEDE-DEEDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAW9-1", "uniprot_id": "A0A0G2KAW9_RAT", "id": "A0A0G2KAW9-1", "name": "Major centromere autoantigen B", "aln": "MTFPARGRGAPTGPQRPRRRVPAAARGRGGGAQRPPASREIPRALRPAPRRAPRWARPAARASRAARHRPPPPREPLCLGRGARRGRQVPPAAGPGPPPRGGDGGAGPRGGGRAGMGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERK--YGVASTCRKTNKL-SPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD--------DFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPSWRTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPA--RQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQ---------------------GGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRR-----------VLLLAGRLAAQS---LDTSGLRHVQLAFFP---PGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSG------------------------LQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITT---------------------------------------------------------------SFKSEGEEEEEEEEEEEEEEEE-GEGEEEEEEEEEGEEEEGGEGEEVGEEEEEVEEEGEVD-DSDEEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQ----------------------------------------------------------------------EEAQCPTLHFLEGGEDSDSDSDEEEEDEEEDEEDEEDEDDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07199-1", "uniprot_id": "CENPB_HUMAN", "id": "P07199-1", "name": "Major centromere autoantigen B", "aln": "-------------------------------------------------------------------------------------------------------------------MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERK--YGVASTCRKTNKL-SPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD--------DFTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP--RQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQ---------------------AGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRR-----------VLLLAGRLAAQS---LDTSGLRHVQLAFFP---PGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSG------------------------LQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITT---------------------------------------------------------------SLKSEGEEEEEEEEEEEEEEGE---GEEEEEEGEEEEEE-GGEGEELGEEEE-VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQ----------------------------------------------------------------------EEAQCPTLHFLEGGEDSDSDS-EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q17RP2-1", "uniprot_id": "TIGD6_HUMAN", "id": "Q17RP2-1", "name": "Tigger transposable element-derived protein 6", "aln": "---------------------------------------------------------------------------------------------------------------MANKGNKKRRQFSLEEKMKVVGAVDSGK--RKGDVAKEFGITPSTLSTFLKDR---TKFEEKVREASVGPQRKRMRS-ALYDDIDKAVFAWFQEIHAKNILVTGSVIRKKALNLANMLGYD--------NFQASVGWLNRFRDRHGIALKAVCREDSDRLMNG----LGIDKINEWHAG-------------EIIKLIADYSPDDIFNADETGVFFQLLPQHTLAAKGDHCRGG-KKAKQRLTALFCCNASGTEKMRPLIVGRSASPHCLKN-------------------IHSLPCDYRANQWAWMTRDLFNEWLMQVDARMKRAERR-----------ILLLIDNCSAHN----MLPHLERIQVGYLPSNCTAVLQPLNLGIIHTMKVLYQSHLLKQILLKLNSSED-Q------------------------EEVDIKQAIDMIAAAWWSVKPSTVVKCWQKAGIVP---------------------------------------------------------------------------MEFAECDTESAASEPDIAIEKLWHTVAIATCVPNEVNFQDFVTADDDLIISQDTDIIQDMVAGENTSEAGSEDEGEVSLPE---------------------------------------------------------------------------------------------------------QPKVTITEAISSVQKLRQFLSTCVDIPDAIFGQLNGIDEYLMKRVTQTLIDSKITDFLQTK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NT04-1", "uniprot_id": "TIGD7_HUMAN", "id": "Q6NT04-1", "name": "Tigger transposable element-derived protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------MNKRGKYTTLNLEEKMKVLSRIEAGR--SLKSVMDEFGISKSTFYDIKKNKKLILDFVLKQDMPLVGAEKRKRTTGAKYGDVDDAVYMWYQQKRSAGVPVRGVELQAAAERFARCFGRT--------DFKASTGWLFRFRNRHAIGNRKGCGEQVLS---------SVSENVEPFRQ-----------KLSMIIKEEKLCLAQLYSGDETDLFWKSMPENSQASRKDICLPGKKINKERLSAFLCANADGTHKLKSIIIGKSKLPKSVKED------------------TSTLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNVLRFHDEDVRALLLLDSCPAHPSSESLTSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLYRWKQLEESLVIFEESDDEQEKGDKGVSK--------------IKIYNIKSAIFNWAKSWEEVKQITIANAWENLLYKK-------------------------------------------------------------------------EPEYDFQGLEHGDYREILEKCGELETKLDDDRVWLNGDEEKGCLLKTKGGITKEVVQKGGEAEKQTAEFKLSAVRESLDYLLD-----------------------------------------------------------------------------------------------------FVDATPEFQRFHFTLKEMQQEIVKKQFQSKIHSRIGSFLKPRPHNIKDSFSGPSTSGSNH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6B0B8-1", "uniprot_id": "TIGD3_HUMAN", "id": "Q6B0B8-1", "name": "Tigger transposable element-derived protein 3", "aln": "---------------------------------------------------------------------------------------------------------------MELSSKKKLHALSLAEKIQVLELLDESK-MSQSEVARRFQVSQPQISRICKNKEKLLADWCS---GTANRERKRKRE-SKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQD---------FVPSIGWLVRWKRRNNVGFGARHVLAPS---------FPPEPPPPGLTS-----------QAQLPLSLKDFSPEDVFGCAELPLLYRAVPGS-------------FGACDQVQVLLCANSRGTEKRRVLLGGLQAAPRCFFGIR-----------------SEALPASYHPDLG-----IPWLEWLAQFDRDMGQQGRQ-----------VALLLAARVVEE----LAGLPGLYHVKLLPLAASSTTPPLPSSVVRAFKAHYRHRLLGKLAAIQSERDGTSLAEAG-------------------AGITVLDALHVASAAWAKVPPQLIFSSFIQEGLAP----------------------------------------------------------------------------GKTPPSSHKTSEMPPVPGGLSLEEFSRFVDLEGEEPRSGVCKEEIG-----------------TEDEKGDREGAFEPLPT---------------------------------------------------------------------------------------------------------------KADALRALGTLRRWFECNSTSPELFEKFYDCEEEVERLCCL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96MW7-1", "uniprot_id": "TIGD1_HUMAN", "id": "Q96MW7-1", "name": "Tigger transposable element-derived protein 1", "aln": "------------------------------------------------------------------------------------------------------------MASKCSSERKSRTSLTLNQKLEMIKLSEEGM--SKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKS---ATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMKAERGVEAAEEKFEASRGWFMRFKERSHFHNIKAQGEAAS----------ADVEAAASYPE-----------ALAKIIDEGGYTKQQIFNVDETAFYWKKMPSRTFIAREEKSVPGFKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYT-----------------KSTLPVLYKWNSKARMTAHLFTAWFTEYFKPTVETYCSEKK----IPFKILLLIDNAPSHPR--ALMEIYEEINVIFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDVSDGSGQSKLKTF--------------WKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTL-------------------------------------------------------------------------IDDYEGFKTSVEEVSADVVEIAKELELEVEPEDVTELLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAG-------------------------------------------------------------------------------------FERIDSNFERSSTVGKMLSNSIACYREIFHERKSQLMRKASPMSYFRKLPQPPQPSAATTLTSQQPSTSRQDPPPAKRVRLTEGSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32896-1", "uniprot_id": "PDC2_YEAST", "id": "P32896-1", "name": "Protein PDC2", "aln": "----------------------------------------------------------------------------------------------------------------MLSIQQRYNICLMAERHPKWTQLELAK-WAYETFQLPKIPSQGTISRLLARKSTYMNCKEHEKDANRLRKPNNLLV-------RKILQEWISQSLWNGIPITSPIIQDTAQAVWHRIPAEHR----EGNGSFSYKWISNFLSKMDVNISVLDEELPK------------TPKVWTFEE-----------RDVLKAYFSKIPPKDLFTLDEAFLSYNLPLDY-----AQYEASSIQRRIEVATVMLCSNLDGSEKLKPVVVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLVRWDKRLVAVNRK-----------IWIVLDDSCCHR-----IINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTRYRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKKAWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKWEYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANEDDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKYLQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQPGPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQNKSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAISQNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEHLEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTLLKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSNNLHLPGNTGFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : . . . : : * : * . : * *: .: : . ::: : . : : * * : :. : * . :: :. . . . .: : : .*. .* : . : . ", "identical_positions": 9, "similar_positions": 47, "identity": "0.82%" }, { "cls_id": "homologset.agr.SGD:S000002490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U4F0-1", "uniprot_id": "RRP8_RAT", "id": "Q5U4F0-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWVEAAPAIVGLRPVTTQVQAATAPPVKGRKRRHLLATLRALEAASLSQQCPSLPGSDSEEE-----EEVGRKKRHFQR---SSLANVSKEVGK-------KRKGKCQKQAPFISDSEGKEVER--TCHRQAPPLGGISAGEEKGKRKCQEYSYLHPTQSLNS--VDQTVHNSRTSTATLDPPKSSRESASPNSSHTLSRKQWRNR----QKNKR-------------------------------------------RHKNKFRPLETQDQVPLKAS----IEETEVPPAPKSDSQETR-----------AGALRARMTQRLDGARFRYLNEQLYSGPSSAAQCLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLR----------------QKPASLVVADFGCGDCRLASSVR-----------------NPVHCFDLAALDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDIR--TFLGAVTKLGFKVIYKDLTNSHFFLFDFEKTGPPRVGPKAQLSG--------------------------LKLQPCLYKHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB85-1", "uniprot_id": "RRP8_MOUSE", "id": "Q9DB85-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWVEAAPAIVGLGAATAQVRPATAPPVKGRKRRHLLATLRALEAASLSQQTPSLPGSDSEEE-----EEVGRKKRHLQR---PSLASVSKEVGK-------KRKGKCQKQAPSISDSEGKEIRR--KCHRQAPPLGGVSAGEEKGKRKCQEYSSLHLTQPLDS--VDQTVHNSRTSTATIDPSKPSPESMSPNSSHTLSRKQWRNR----QKNKR-------------------------------------------RHKNKFRPLQTPEQAPPKAS----IEETEVPPVPKSDSQESR-----------AGALRARMTQRLDGARFRYLNEQLYSGPSSAARRLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLR----------------QKPASLVVADFGCGDCRLASSVR-----------------NPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKTGGLLKVAEVSSRFEDIR--TFLGAVTKLGFKIIYKDLTNSHFFLFDFEKTGPPRVGPKAQLSG--------------------------LKLQPCLYKRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43159-1", "uniprot_id": "RRP8_HUMAN", "id": "O43159-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWAEAAPVAAGLGPVISRPPPAASSQNKGSKRRQLLATLRALEAASLSQHPPSLCISDSEEE-----EEE-RKKKCPKK---ASFASASAEVGK-------KGKKKCQKQGPPCSDSE-EEVERKKKCHKQA-LVGSDSAEDEKRKRKCQKHAPINSAQHLDN--VDQTGPKAWKGSTTNDPPKQSPGSTSPKPPHTLSRKQWRNR----QKNKR-------------------------------------------RCKNKFQPPQVPDQAPAEAP----TEKTEVSPVPRTDSHEAR-----------AGALRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLLYHRGFQSQVKKWPLQPVDRIARDLR----------------QRPASLVVADFGCGDCRLASSIR-----------------NPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVR--TFLRAVTKLGFKIVSKDLTNSHFFLFDFQKTGPPLVGPKAQLSG--------------------------LQLQPCLYKRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5G5-1", "uniprot_id": "A0A8M9Q5G5_DANRE", "id": "A0A8M9Q5G5-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFAEEDWTDS-PSLNGS-PLSAKLSPASGKK-KAVGKQSLLRTLQTLGSVPDWEVGKAVEEDSDEEKDASAAVKKPKKKRCKKRKRKSNADNEEKQMGEEDSEAPVKKKKTTTKPVKKTKRSVVSEEPKKDDNAVRAQLEKNESQTEKKLSRQQWKNKMKNKRKSKNKYLQKQTSDDTSPKKETLVQTQQIKEFKNPLKPDRTSKKTSKKINKIIEKNASSIGDNAGTCTDSKTDKTIFTETIKVDDSLNNSYNTSQEIGETDKHAKKTKKLQAEKLRRILKSKSSRTDSDKVTETPKDAAVDLKGVEDQTAPLDPSTALRLKMEKQLEAARFRFINEQLYTSTSAAAKRMFQQDPDAITIYHKGYTTQVQHWPTNPVDSIISYIC----------------QKPASLVVADFGCGDCKIARSVK-----------------NKVHSFDLAPVCELATACDMAKVPLGDSTVNIAVFCLSLMGTNLGDFLAEANRVLVMGGVLKIAEVASRFENVH--SFVRALSNMGFKIVNKDTENSHFFSFEFIKTR--KAPENAKKFG--------------------------LQLKPCLYKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K2B0-1", "uniprot_id": "RRP8_DROME", "id": "Q7K2B0-1", "name": "Ribosomal RNA-processing protein 8", "aln": "-------------------------------------------MKPFEVPPWEEGADIIEFEPVNPSGNGVAAKKKPKK---------------------------KKPKKKKAAVPNENLNVNKAAEKFTYRQGRGPLAPPQDSSDDDYEDVEDGIRAMHKVKSGRIEKQRPPTQATKGGKKELKLKPELAQAALEAMEATSSTTPAANS------------------------------------------------------------------------------------------------------------LASKLQSELLGGRFRYINEQLYSTTSRKAEALFRKDSSAFEAYHAGYRQQVEKWPINPLNRIIKTIK----------------KIPKTAIIGDFGCGEGKLAQSVP-----------------NKVYSMDLVAARSDIIACNITDTPLQARTLDVAVYCLSLMGTDLNEFFLEANRVLKLHGTVYIAEIQSRFQDVR--EFVRCLNACGFDLNKKDVAVNYFYFFQFKKMR--HVPKNTKMKA--------------------------FSLKPCLYRKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38961-1", "uniprot_id": "RRP8_YEAST", "id": "P38961-1", "name": "25S rRNA (adenine(645)-N(1))-methyltransferase", "aln": "-------------------------------------------MALFNVEGWSIKTKTVAFDNKTNKSS-------------------------------------KDKKKNNRKNGKLTREQKLKEETEAELKEQVEDIPSEGSVAKDIPKKNQEKSDQNETSKKRKHDEEAPLMQVKENIEKPTKKQLTP-------------------------------------------------------------------------------------------------------------------------------LQQKMMAKLTGSRFRWINEQLYTISSDEALKLIKEQPQLFDEYHDGFRSQVQAWPENPVDVFVDQIRYRCMKPVNAPGGLPGLKDSKEIVIADMGCGEAQLALEINNFFKNYNKKAKKYLKRRHKVHSFDLKKANERITVADIRNVPLPDESCTIVVFCLALMGTNFLDFIKEAYRILAPRGELWIAEIKSRFSDGKGNEFVDALKLMGFFHKKTFDENKMFTRFEFFKPPAEIIEERRQKLERRQKFIEVETEKEELEKKRRKIAEGKWLLKPCIYKRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . * . . . : . .. : . . * :: .* ..***::*****: .* * :::::.. : ** *: **: ** :*:: : : : . ::.*:***: ::* .: : *:.:** ..:: ..** : :.*:**:****:: :*: ** *:* * : :**: ***.: : *: .:. ** . . * *:* * . : *:**:*::*", "identical_positions": 61, "similar_positions": 89, "identity": "10.18%" }, { "cls_id": "homologset.agr.SGD:S000002491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8T4-1", "uniprot_id": "TV23B_MOUSE", "id": "Q9D8T4-1", "name": "Golgi apparatus membrane protein TVP23 homolog B", "aln": "MLSQDSNDDT---EDVSL-FDAEEETTNRP-RKSKIRHPVASFFHLFFRVSAVVVYLLCELLSSSFIACMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGK-SHWVFESRKSTPQDNKTISEAESRIFWLGLIACPVLWVIFAFSALFSFRVKWL---------AVVIMG------VVLQGANLYGYIRCK-----------VGSKKNLTS-----MATSYLGKQFLR-QNTGDGQTS----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVP7-1", "uniprot_id": "A0A8I5ZVP7_RAT", "id": "A0A8I5ZVP7-1", "name": "Golgi apparatus membrane protein TVP23 homolog", "aln": "ISKQDSNDDT---EDVSL-FDAEEETTSRP-RKSRIRHPVASFFHLFFRVSAVVVYLLCELLSSSFIACMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGK-SHWVFESRKSTPQDSKTISEAESRIFWLGLIACPVLWVIFAFSALFSFRVKWL---------AVVIMG------VVLQGANLYGYVRCK-----------VGSKKNLTS-----MATSYLGKQFLR-QNAGDGQTS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYZ1-1", "uniprot_id": "TV23B_HUMAN", "id": "Q9NYZ1-1", "name": "Golgi apparatus membrane protein TVP23 homolog B", "aln": "MLQQDSNDDT---EDVSL-FDAEEETTNRP-RKAKIRHPVASFFHLFFRVSAIIVYLLCGLLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGK-SHWVFESRKESSQENKTVSEAESRIFWLGLIACPVLWVIFAFSALFSFRVKWL---------AVVIMG------VVLQGANLYGYIRCK-----------VRSRKHLTS-----MATSYFGKQFLR-QNTGDDQTS----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96ET8-1", "uniprot_id": "TV23C_HUMAN", "id": "Q96ET8-1", "name": "Golgi apparatus membrane protein TVP23 homolog C", "aln": "MLQQDSNDDT---EDVSL-FDAEEETTNRP-RKAKIRHPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGK-SHWVFESRKESSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTVKWLRRSRHIAQTGLKVLGSRDPPASAFQSAGITGVSRCPGHPSRKFHQVDINSFTRITDRALYWKPAPRLSSPPLR-AAPGNCQQMAPARLFLSLRLWAWRGGGESPNSRGTGEPGPKFHLASGMH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NH52-1", "uniprot_id": "TV23A_HUMAN", "id": "A6NH52-1", "name": "Golgi apparatus membrane protein TVP23 homolog A", "aln": "-MKQALVDDT---EDVSLDFGNEEELAFR---KAKIRHPLATFFHLFFRVSAIVTYVSCDWFSKSFVGCFVMVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGK-SHWIFEARK-VSPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLFSLKLKWLA---------LVVAG------ISLQAANLYGYILCK-----------MGGNSDIGK-----VTASFLSQTVFQTACPGDFQKPGLEGLEIHQH------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M668-1", "uniprot_id": "A0ABK0M668_RAT", "id": "A0ABK0M668-1", "name": "Golgi apparatus membrane protein TVP23 homolog", "aln": "-MKQGLVDDT---EDVSLDFGNEEELAFR---KAKIRHPLATFFHLFFRVSAIVTYVCCDWFSRSFVGCFVTVLLLLSFDFWSVKNVTGRLMVGLRWWNQIDEDGK-SHWIFEARKQVSANHMAATEAEARIFWLGLIICPVIWIMFFFSTLFSLKLKWLAS-LFCPMQALVIAG------ISLQAANLYGYVLCK-----------MGGDGDMST-----VAASFLPQTVFQTDAPGDFEKPRLEGLDIHQH------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IQC1-1", "uniprot_id": "TVP23_DROME", "id": "Q8IQC1-1", "name": "Uncharacterized Golgi apparatus membrane protein-like protein CG5021", "aln": "-MASATVRNVPLLDDDTIPFGEEDEMRDPSRAGQKYTHPYVTFFHLFFRGAAILIYMFCGWFSDSFITSFVFVVLFLSADFWTVKNISGRLLVGLRWWNYVDDDGV-SHWVFESKNSESYQS-RVNKNEQRIFWLGLILCPVFWGLFFLFALFGLKFKWLL---------LVMIA------IALNAANLYGYVKCN-----------YGANKDLNS-----AATDFVKTQFFK-NAVDIMTRPSGAPPPTNVRPTGVV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38962-1", "uniprot_id": "TVP23_YEAST", "id": "P38962-1", "name": "Golgi apparatus membrane protein TVP23", "aln": "----------------------MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLN-FTPQFITVVLLLSFDFYLTKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQYAPGP-PINAIDSKLFWWSMYVTPVIWGVFAVLCLLRLKIFYLI---------LVIVA------MCLTAWNTYGFRCCDR----------WEPNSGQSD-------GQDTNNWFALPSVPGFENLSRLANIQSFFQRQ----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : ** *** : .:: : : * :: ::*:** **: .**::** :* **** : . *:: **: : . . : ::** .: .::* :* . *: : . :* : : . : . . * * . ", "identical_positions": 31, "similar_positions": 48, "identity": "10.95%" }, { "cls_id": "homologset.agr.SGD:S000002493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60059-1", "uniprot_id": "SC61G_HUMAN", "id": "P60059-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------------------------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60060-1", "uniprot_id": "SC61G_MOUSE", "id": "P60060-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------------------------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F2Z4R1-1", "uniprot_id": "F2Z4R1_DANRE", "id": "F2Z4R1-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------------------------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AAZ9-1", "uniprot_id": "A0A8I6AAZ9_RAT", "id": "A0A8I6AAZ9-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------------------------------VDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFPIMGFIGFFVKLIHIPINKIIVGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K7E7-1", "uniprot_id": "A0A0G2K7E7_RAT", "id": "A0A0G2K7E7-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------------------------------MDQVMLFVEPSRQFVKASILLVKGCSKPDRKKFQKIAVATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWE9-1", "uniprot_id": "S61G2_DROME", "id": "Q9VWE9-1", "name": "Protein transport protein Sec61 gamma-2 subunit", "aln": "--------------------------------------MDKVVKFAEPGRAFAKDSIRLVKRCTKPDRKEFQKIAIATAVGFCIMGFIGFFVKLIHIPINNIIVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V668-1", "uniprot_id": "S61G1_DROME", "id": "Q9V668-1", "name": "Protein transport protein Sec61 gamma-1 subunit", "aln": "--------------------------------------MDKVVKFAEPGRAFAKDSIRLVKRCTKPDRKEFQKIAIATAVGFAIMGFIGFFVKLIHIPINNIIVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBU4-1", "uniprot_id": "A1ZBU4_DROME", "id": "A1ZBU4-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "MEQLLSRRRRYRAKCAKRSVRKFLPDLKCKSVERIKCQIKDLLILMVPSKDFYKNSLRFYKRCTKPDRREFQRISIGIGVGFLIMGLIGFVVKLMHIPIVNIIMD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35179-1", "uniprot_id": "SC61G_YEAST", "id": "P35179-1", "name": "Protein transport protein SSS1", "aln": "-----------MARASEKGEEK-------------KQSNNQVEKLVEAPVEFVREGTQFLAKCKKPDLKEYTKIVKAVGIGFIAVGIIGYAIKLIHIPIRYVIV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : . * : . : *.*** ::: :* . .:** :*:**: :**:**** :*: ", "identical_positions": 18, "similar_positions": 23, "identity": "16.98%" }, { "cls_id": "homologset.agr.SGD:S000002494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LB97-1", "uniprot_id": "A0ABK0LB97_RAT", "id": "A0ABK0LB97-1", "name": "", "aln": "-------------------------------MAPAMQSTELQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGSFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVN-------------SSEAQHLFIQTFWQTVNREWQGIDKLRLDKYYMLIRLVLRQSFEVLKRNAWEESQITLFLDILMKEILSPES-RSPNGVRSHLIDVYLDELSTVGGRELLADQNLKLIDPFCRIAAKTKEPQTKASPDYTRSCSDEGKKAEVLVPVNSATSWLPIQDALPHQTLSFCLSCGTCHTLVQTVAKGVFEVIVDQSAFVPEESVEEQKTKE-DG----NGLPANELACQKVVGGKKTAL--DECLRDGVIGSRERDICAALKDSGSPLQFDYKAVADRLLEIANSKSTPPFNRKRLCRLVRKFQDLSEGN-GAQLSFAEDISAGENGQALSQRRHKRKRKKLLERAALEREEGNTVSAAGEEDGGGHIHKRKRKKRKRSHFQSDTQDLGSVAEAAVPSADSEPGAAQRHA--LQACVAAPTAEATSNTRENS-SEPTPATPIHSKRKRQRKKNLRAHREIWKSTTLPQEDVSKNDPASGQPQ--TALISSSEGGQARKRKRKLGALPVSSGDLT------VQKAGTPASPVEGNDGQTTLPRCKRSQKKTAS-NTLDHYDPSSQKTAISKKRKK-MKQTS-----NGVLECSAGQIQALGSN---RTLKKP-LKMEDDLVKFDTRFLPKALFFRKAKNSSATRPQGPTVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTPTSSPASTPLSTMKLPATTPKRRPRAADFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YK2-1", "uniprot_id": "RRP1B_MOUSE", "id": "Q91YK2-1", "name": "Ribosomal RNA processing protein 1 homolog B", "aln": "-------------------------------MALAMQSSEFQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGSFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVN-------------SLEAQYLFIQTFWQTMNREWQGIDKLQLDKYYMLIRLVLRQSFEVLKRNAWEESQITLFLDILMKEILSPES-QSPNGVRTHLIDVYLEELTTVGGAELLADQNLKLIDPFCRIAAKTKD-----------------------------------------------------HTLVQTVARGVFEVIVDQSACVPQESVEERKTKE-DG----SGFPTKALACRKAVSGKKAAL--DECLRDGVIGSRERDICAALKDSGSPLQFDYKAVADRLLEIANSKSTPPFNRKRLCRLVRKFQDLCEGN-GAPLSSAEDN---------GQRRHKRKRKKLLE-----SEKGDTVSPAAEEDSGGHIHKKKRKKRKRSHFQPDTQNLDAVAVPKVPDSESEPDTAQRQAPCGQACVTEPTAEAVSSIGENS-SKPTPVMPIHNKRKRPRKKKLRAHKEICKSTTLPQEDMSKNDAVSGHSQSSAAHISSSEGVQAQKRKRKLGALPDSSSDLP------VQKSGTPTSPVEGKDGQTTLPRCKRSQKKTAS-STLDPCDPSSQKPAISKKKKKTMKLMS-----NGVLESNPGQIQALGSN---RTLKKP-LKTEDDFVKFDTRFLPKPLFFRKAKNSSATRPQGPAGQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTATSSPASTPLSPMRLPATTPKRRPRAADFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14684-1", "uniprot_id": "RRP1B_HUMAN", "id": "Q14684-1", "name": "Ribosomal RNA processing protein 1 homolog B", "aln": "-------------------------------MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTIAQLVHAVN-------------NSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYMLIRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPES-QSPNGVRFHFIDIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTKD-----------------------------------------------------HTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVGDGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDYKAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKA--LKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQ--GPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKK-MRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56183-1", "uniprot_id": "RRP1_MOUSE", "id": "P56183-1", "name": "Ribosomal RNA processing protein 1 homolog A", "aln": "------------------------------MVPGVPLPPEIQLAQRLAGNEQVTRDRALRKLRKYIEARSQRATGGFTPDELLKVWKGLFYCMWMQDKPLQQEELGRTIAQLVHAFH-------------TTEAQHQFLKAFWQTMIREWVGIDRLRLDKFYMLMRMVLSESLKAVKARGWDERQIEQLLELLTTEILNPDS-QAPSGVKSHFLEIFLEELAKVGAAELTADQNLQFIDPFCQIAARTKD-----------------------------------------------------SQVLHKIIQSIFQTIVEQAPLAIEDIMNELDTQSGEG---------------------------EASDGDDGEASDGDDGEASDDDDG-------EASDGGDGDVADSDDSDGAD----------------------------------------------------------DDDGDVSDGDGGDNDEGDSNKSSEGEQDLQDTPPKKLPAGTAHRAGPEADKEQAWDDEEN---AGPVLQFDYEALANR----------LFKLASRQSTPSQNRKRLYKVIQKLRELAGGTFPEDDVPEKAYK------KMLEGRRERKKKK-KRLPKPQ-------------------------------PQNKEAGSEAES---------SSADPGPGRKRKR-----------NRKTDEKAGQGGPPG-----------------------KRRKP----GARAKGAGAQQPK-------KRIQSSQSAE-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56182-1", "uniprot_id": "RRP1_HUMAN", "id": "P56182-1", "name": "Ribosomal RNA processing protein 1 homolog A", "aln": "------------------------------MVSRVQLPPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLFYCMWMQDKPLLQEELGRTISQLVHAFQ-------------TTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYMLMRMVLNESLKVLKMQGWEERQIEELLELLMTEILHPSS-QAPNGVKSHFIEIFLEELTKVGAEELTADQNLKFIDPFCRIAARTKD-----------------------------------------------------SLVLNNITRGIFETIVEQAPLAIEDLLNELDTQ------------------------------------DEEVAS-------------------------------DSDESS----------------------------------------------------------------------EGGERGDALSQKRSE-----------KPPAGSICRAEPEAGEEQAGDDRDS---GGPVLQFDYEAVANR----------LFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACR------RLLEGRRQKKTKKQKRLLRLQ-------------------------------QERGKGEKEPPS---------PGMERKRSRRRGV-----------GADPEARAEAGEQPGTAE--RALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPE-------KKKKRRE----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJV2-1", "uniprot_id": "A0A8M9QJV2_DANRE", "id": "A0A8M9QJV2-1", "name": "", "aln": "---------------------------------MATQAAEVIFAQKLAANEKSVRSKALLKLRKYIRIRSERAPGGFSEEELLKIWKGLFYCLWMQDLPLLQEELSTKISALLFSFR-------------TVDSQFLFFKTFLQTMKREWNGIDRLRLDKFYQLVRFVFRQMFEMLKKQEWEPSVLQEFLQLFSDQLLQSSS-AAPSGLIMHIMELYMTELAAVGAAELTAAQNLSLIEPFCRTMSRTRD-----------------------------------------------------RVLLKAIGSSIFSTIVDQVPFAIADLLREISTTEEED-----------------------QDGETQTNDAEENTSHPGEDAGDKGSDEAVLQFDYGAVADRLFEVASHSNIPSFNRSQIYKFVKVFRDLSEG--------------------------------------VFPQDEVEDVSSDEDEFDDDRRRKKKKKKSSSRQQDSLNTHTGEAETSTPADDKPKNKKRRKKKKKSGLKSVEEPENCTAPQTPAEDQKKKKKTTQQHTETADGGQQRSETHTTPALMEDDGGAPAEKPQKKKKR---KMQTPAEADQHTLMKRRKKSLHTHTNGDAP---------IEETTAEKPQKKNIQKPLNGHTQKPQKKKMMMQITNTPLTTEKPQKKKLS-----------QKRAAAALVNGHTEAEDP---ALPVSTDRKMKKKFVLSQKKAPAPLFCKGLKNTRISAAA---------KTDRKKVTFGLKNNKTVEFRKTDRSALLSP---DRLPFDPSRTPKSGVLKTPSPS---------------AMKRPSAADFF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35178-1", "uniprot_id": "RRP1_YEAST", "id": "P35178-1", "name": "Ribosomal RNA-processing protein 1", "aln": "-------------------------------------METSNFVKQLSSNNRKTRVNALEALKKYLTAKQFKEN---KQIEFNKLWKGLYYAMWFSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGFWKVMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVLRWLPLSGSPKVYTGIPIHIVDILLDEWERLLKDGDEDDE---------DEENKEEE--------------------------------------------------------MRKIAESAKKTPLADVIAIFQDIVADYNNSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLREKIKEDLFSDTRLVSWDILEGETQHNDSS------NESEEEEEEEWKGF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJZ7-1", "uniprot_id": "RRP1L_DROME", "id": "Q9VJZ7-1", "name": "Ribosomal RNA processing protein 1 homolog", "aln": "MVTRKKPVKRNAEAAEIQVEQEEDASQPKVAKELMVVAQEVKIIRALACNDVVERNRQIRILRKWFKAR-AGSSFPFNEDDFMRIWKGLYYTMWMSDKPLVQEELAEKLAQMVDSFGG------------NTACSLAYFSAFMRTMCQEYFGIDQWRMDKFLMLTRRMVRYLLRFLKQNNWNADLIAAFNSSMQLSVMSEQP--KSRGMTMHYLDVFFEELAKAANGEITAAQVNMFLRPFVTYIATQRD-----------------------------------------------------AKLVAQCRTRVLYHLMYQSDLG-RQYSEKYNAWKQMG--------------------------FPTASIDDIEKLDSGFDEEDDEVNAEEEQPRATSLDPRAGNVDVHMPELPLN-----------------------------------------------------------ADCVLDELQTQLRTNDFNSKRRKGLRKLIQIFETYQRGEFPLGVRTMPKVEGQTLSEMVEQKVAALDKMEDEVFATGRKLKKLNKSKRKRLLQSINFEEVDEHNYDEVISKALPPELQKKVNYNAKVRSSINNAWVVEEVKEAEPKSKKAKKEEPPQQNKDDQ------TKVKKKSQLKPKNDQSKPKIEDQPTLKAEKEEPAKRKKLDHSKTKEEQSKPKTD-----------EQPKPTPKVEGQSKAKPTPKTKAAGVDDDAPTNGWDAPLEDGEQDIFVPSRKLQVKQANSKLPQSTPKQPARAEFATPQTGSGKHVRIVTKSNCIYPKSDYYRQLKLSPQVPYDANRLPGKSALKPHWIPGPIHPSYKAKRLFNDTL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: .: * . : *:::: : . :: ::****:* :*..* * *:.*. :. : . . : * :.: *: .**: ::**: * * :. :. :: . *: : . . : . *: * ::: : * : .: : : : : . . . . * ", "identical_positions": 26, "similar_positions": 68, "identity": "3.02%" }, { "cls_id": "homologset.agr.SGD:S000002495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZG5-1", "uniprot_id": "SLU7_RAT", "id": "Q80ZG5-1", "name": "Pre-mRNA-splicing factor SLU7", "aln": "-MSAAAVDPVSATPMTGSKEMNLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPT--LKHQRPQPEKQKQFSSSGEWYKRGVKENSITTKYRKGACENCGAMTHKRKDCFERPRRVGAKFTGTNIAPD--EHIQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKINNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKESVN-SEECIINDATGEEPVKKPQ------------------TLMELHQEKLKEEKKKKKKKKK-HRKSSSDSDDDEERKQEKLKKALNAEEARLLHVKEIMQVDERKRPYNSIYETREPTEEEMEAYRMKRQRPDDPMASFLGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHJ9-1", "uniprot_id": "SLU7_MOUSE", "id": "Q8BHJ9-1", "name": "Pre-mRNA-splicing factor SLU7", "aln": "-MSAAAVDPVSATPMTGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPT--LKHQRPQPEKQKQFSSSGEWYKRGVKENSITTKYRKGACENCGAMTHKRKDCFERPRRVGAKFTGTNIAPD--EHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKINNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKESVN-SEECIITGATAEESVKKPQ------------------ALLELHQEKLKEEKKKKKKKKK-HRKSSSDSDD-EERKQEKLKKALNAEEARLLHVKEIMQIDERKRPYNSIYETREPTEEEMEAYRMKRQRPDDPMASFLGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95391-1", "uniprot_id": "SLU7_HUMAN", "id": "O95391-1", "name": "Pre-mRNA-splicing factor SLU7", "aln": "-MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPT--LKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKKDCFERPRRVGAKFTGTNIAPD--EHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVN-SEECIINEITGEESVKKPQ------------------TLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDD-EEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3F2-1", "uniprot_id": "SLU7_DANRE", "id": "Q5U3F2-1", "name": "Pre-mRNA-splicing factor SLU7", "aln": "-MAAEAGKASEG-------MVDLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPT--LKHQRPQEENQSKFAPIGDWYKRGVQEKSVNTKYRKGACENCGALTHKKKDCLERPRKVGAKFSGTGIAPD--EHQQVQLSMDYDGKRDRWNGYDPDEHMRIVEEYSKVDLAKRTLKAQKLQEELASGKLMDQANSRKH--------EEAVQDHSSEDEDEDKYVDDFDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYSNTGKNPEEVGYAGDNFVRYSGDTISMAQTQLFAWEAYEKGSEVHLQADPTKLELLHQSYKVKKDDFKEKQKETILEKYGGSEHLDAPPRELLLAQTEEYVEYSRHGAVLKGQEKAVAQSKYEEDVLNNNHTCIWGSYWKDGYWGYKCCHSMVKQSYCTGEAGKKVVSNSCTPFEEDVEEAQTSEEPK------------------TLLQMHQEKLKD-KKKKKKSKK-HRDSDSSDEEDEAKKKEKLKKALSAEEQRLKQVAELMQVDERKRPYNSLMEVREPTEEEMEAFRMKRCRPDDPMASFLGQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAQ7-1", "uniprot_id": "SLU7_DROME", "id": "Q9VAQ7-1", "name": "Pre-mRNA-splicing factor Slu7", "aln": "MSSGPMRTPVSQIILSKHDQDAEEEPKKKSREDWRKAKELEEARKAGTAPAAVDEEGRDINPHIPQYISNAPWYYG-SAGPT--LKHQRPQHEDEQ--GQLDKRAPKGLNTARIITKFRKGACENCGAVTHKRKDCLERPRKVQAKYAESIVVHD--EHLVNEAAVNYDEKRDRWSSYDPANHREIIEEYEKVEEAKRQLKAEKLKNDPD-------------------------AEISDEEGNEDKYVDEVDMPGTKVDSKQRITVRNLRIREDTAKYLRNLDPNSAYYDPKTRSMRDNP--NPAVPEEEAEFAGENFVRFSGDTTAQATAQLFAWEAHGKGVDVHLLAEPTKLELLQKEYEQKKEQFKSSTKTHIVEKYGGEEHLQVPPKSLLLAQTEEYIEYSRSGKVIKGVEKPKARSIYEEDVYINNHTTVWGSFWNAGRWGYKCCKSFIKNSYCVGMQEPEGYSEHHSTSSTAAATTEPAAQSQFKVPEVPPERPTSEVDSASSSEPSSSEEEEVKPEKKKTKKKSKKREKKKKAKEQRKQ-KGKNKETKDKDKTKEKDIPEELDDRKRAYNSMYDVKAPTEDEIEEWKKKRPRAEDPMLQFM--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02775-1", "uniprot_id": "SLU7_YEAST", "id": "Q02775-1", "name": "Pre-mRNA-splicing factor SLU7", "aln": "-MNNNSRNNENRSTINRNKRQLQQAKEKNENIHIPRYIRNQPWYYKDTPKEQEGKKPGNDDTSTAEGGEKSDYLVHHRQKAKGGALDIDNNSEPKIGMGIKDEFKLIRPQKMSVRDSHSLSFCRNCGEAGHKEKDCMEKPRKMQKLVPDLNSQKNNGTVLVRATDDDWDSRKDRWYGYSGKEYNELISKWERDKRNKIKGKDKSQTDETLWD-----------------------TDEEIELMKLELYKDSVGSLKKDDADNSQLYRTSTRLREDKAAYLNDINSTESNYDPKSRLYKTETLGAVDE-----------------------KSKMFRRHLTGEG--------------------LKLNELNQFARSHAKEMGIRDEIEDKEKVQHVLVANPTKYEYLKK-----------------------------------------------------------------------------------------------------------------KREQEETKQ--------------------PKIVSIGDLEARKVDGTKQSEEQRNHLKDLYG-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* . . : . : ... .:: : :. .: .. : .. . : * : . .. : : .. . *.*** **.***:*:**:: . : ::* ::*** .*. :: .::.:: : . * * :. :: : . * . : * *... . .: :: . *:*** * **.:::...: ****:* : :. :::* . :* * ::::. : * .* : . :*. . ** : * ::::.*: : . . . . : ::::. :.: ", "identical_positions": 46, "similar_positions": 127, "identity": "7.53%" }, { "cls_id": "homologset.agr.SGD:S000002498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD23-1", "uniprot_id": "D3ZD23_RAT", "id": "D3ZD23-1", "name": "", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAVVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKR-----------------------------------------PQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61221-1", "uniprot_id": "ABCE1_HUMAN", "id": "P61221-1", "name": "ATP-binding cassette sub-family E member 1", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61222-1", "uniprot_id": "ABCE1_MOUSE", "id": "P61222-1", "name": "ATP-binding cassette sub-family E member 1", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VSS1-1", "uniprot_id": "ABCE1_DROME", "id": "Q9VSS1-1", "name": "Protein Pixie", "aln": "MSRRKENEEVDKQTRIAIVSDDKCKPKRCRQECKKTCPVVRMGKLCIEVTPTSKIASLSEELCIGCGICVKKCPFEAITIINLPSNLEKHTTHRYSKNSFKLHRLPIPRPGEVLGLVGQNGIGKSTALKILAGKQKPNLGKYANPPDWTEILSYFRGSELQNYFTKILEDNLKALVKPQYVDQIPKAVRG---AVGDLLDKKDER--ELQTKICEMLDLSHIRDREIAQLSGGELQRFAIAMVCIQNADIFMFDEPSSYLDVKQRLNAALTIRSLLHPTKFIIVVEHDLSVLDYLSDFICCLYGVPGCYGVVTMPFSVREGINIFLDGFVPTENMRFRTESLTFKVSESATEEEIKRMN-HYVYPAMVKTLGKFELTVEKGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKPQKISPKFQNHVRHLLHDKIRDAYVHPQFIADVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFVVEHDFIMATYLADRVIVIEGQPSVKTTAFSPQSLLNGMNRFLELLGITFRRDPNNFRPRINKNNSVKDTEQKRSGQFFFLEDEACN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03195-1", "uniprot_id": "RLI1_YEAST", "id": "Q03195-1", "name": "Translation initiation factor RLI1", "aln": "--------MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFISEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPASVREGINIFLDGHIPAENLRFRTEALQFRIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTDVVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLKNLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNYFFLDNTGI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*****. ******:******::****: ********* **** :** ********:***** *: *:***:*** ..****. *:******* ****:****** *********************:: :**:* **:.*************:***::**::******:**:* :* **.:*. : * : : *:* :: .*:: .********** .: *:*:**::***************:** ****: * :::* **************:* :****. *****:* ************.:*:**:*** :* *:::::: : : . : **.: *. *.* * : *.*:****:*::*********:*::*** *:** ::* **:* *****:** . **:*:..***. : :*** :**:**::*::*:***** **********:.*.** ***:***************::.::*::* *::** * *:**. * :*******.:****** :* * *** **::***:: ", "identical_positions": 348, "similar_positions": 129, "identity": "56.4%" }, { "cls_id": "homologset.agr.SGD:S000002499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61089-1", "uniprot_id": "UBE2N_MOUSE", "id": "P61089-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61088-1", "uniprot_id": "UBE2N_HUMAN", "id": "P61088-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQX9-1", "uniprot_id": "UBE2N_RAT", "id": "Q9EQX9-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARAWTRLYAMNNI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JXB2-1", "uniprot_id": "UE2NL_HUMAN", "id": "Q5JXB2-1", "name": "Putative ubiquitin-conjugating enzyme E2 N-like", "aln": "MAELPHRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIETARAWTRLYAMNSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35128-1", "uniprot_id": "UBE2N_DROME", "id": "P35128-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTG-PNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJS5-1", "uniprot_id": "Q9VJS5_DROME", "id": "Q9VJS5-1", "name": "UBC core domain-containing protein", "aln": "MAALTPRIIKETQRLLEDPVPGISATPDECNARYFHVLVTG-PKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKIFHPNIDRVGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAELWKVNERRAIQLARECTLKHAMQN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52490-1", "uniprot_id": "UBC13_YEAST", "id": "P52490-1", "name": "Ubiquitin-conjugating enzyme E2 13", "aln": "MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEG-PEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. ******::*: :*****.* *.: * ***:* : * .::**:*.* *: ** *.::*** ******:***:***:*:: **.**:** :*********:******** :***:*******.* * ** * ** * :* :. ", "identical_positions": 88, "similar_positions": 35, "identity": "57.14%" }, { "cls_id": "homologset.agr.SGD:S000002500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UQ17-1", "uniprot_id": "AT8B3_MOUSE", "id": "Q6UQ17-1", "name": "Phospholipid-transporting ATPase IK", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MDGVHLGENLEDKDTEFTWEVKANDRT---------------------------------------------------YHKQ--FKKKGFLCWRQKKYKSNAIHTAKYNIFSFLPLNLYEQFHRMSNLYFLFIIILQGIPEISTLPWFTLFAPLVCLFVIRATRDLVDDIGRHRSDKIINNRPCQILR-------------------------------------------------------------------------------------------------------------------GKSFLWKKWKNLCVGDVVCLSKDSIVPADLLLLASTEPSSLCYVETADIDGETNLKFRQALTVTHHELTSPKKMASFQGTVTCEEPNSRMHHFVGSLEWNSRK------YPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVALIFLSLVIASLLLTVGFTFMVKQFKAKH--YYMSPTHGR--SDAMESFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLNMYYEPLDMPAKARSTSLNDQLGQVQYIFSDKTGTLTQNIMTFKKCCINGCIY----------------------------------------------------------------------------DSDDEHGTLRKRNPYAWNPFADGKLQFYNKELESLVQGRQ--------DRAVQEFWRLLAICHTVMVQEKDNQ---------------------------------------------------------------------------------------------------------------------LLYQAASPDEEALVTAARNFGYVFLSRTQDTITLVELGEER--VYQVLAMMDFNSVRKRMSVLVRNP------EGSICLYTKGADTVILERLR-----------SKGV-MEATTEEVLAAFAEQTLRTLCLAYKDVEEDAYKEWEPEHQEAALLLQNRAQALHQVYNKMEQNLQLLGATAIEDKLQDGVPETIKCLKKGNIKIWVLTGDKPETAVNIGFACQLLSENMIILEDKDINQVLERYWEDNVHQKAFKMMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEVAQEPVVSALDFLQKRRISQMWRNAGPSLGTSHSADSKIRESPEVQ-RER-AFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRVCKFLRYFFYKTVASMMAQIWFSLVNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYMAGQKGELFNYSIFMQAITHGTITSMINFFVTV-MVSSDMSK--AGSSH-DYQSLGVLVAISSLLSVTLEVMLVVKYWTLLFVGAVVLSLSSYVLMTSLTQSLWMYRISPKTFPFLFADYNVLFEPCSLLLIVLNVALNVLPMLALRTIHRTVLK------QRPKGE---EEAPSEEVAVEPAMRHLRRGI------------------PARRSSYAFSHREGYANLITQGTILRRQTHVDDSDGGTVCESLNPPEEDIPLQNKDSVFNPRKISILAKKRRHFFGKGSQEEVHPNTSSQTMEKQPTIHRD-SETQKLPTTTSATSGKLLPSASEDEAFYSVASQYTLASQPKHTDVHSSFWKSPLWRDSASSSPSQLEVPRKQS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE62-1", "uniprot_id": "D3ZE62_RAT", "id": "D3ZE62-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------MGDTPTAQEAPRRRMIHTGRSGKYRLRFGGPTSMDDAHLEEDLEDKDTEFTWEVKANDRA---------------------------------------------------YHKQ--FRKKGFLCWRQKKYKSNAIHTAKYNVFSFLPLNLYEQFRRVSNLYFLFIIILQSIPEISTLPWFTLFAPLVCLLMIRAARDLVDDIGRHRSDRIINNRPCQILK-------------------------------------------------------------------------------------------------------------------GKSFLWKKWKNLCVGDVVCLSKDNIVPADLLLLASTEPSSLCYLETADIDGETNLKFRQALMVTHHELTSPKKMASFQGIVTCEEPNSRMHHFVGSLEWNSRK------YPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVILIFMSLVIASMFLTLGFAFMVKEFKAKH--HYMSSMQGR--TDAMDSFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLSMYYEPLDIPAKARSTSLNDHLGQVQYIFSDKTGTLTQNIMTFKKCCINGCTY----------------------------------------------------------------------------DSDDEHGTLRKRNPYSWNPFADGKLQFYNKELESLVRGKQ--------DRAVQEFWRLLAICHTVMVQEKDNQ---------------------------------------------------------------------------------------------------------------------LLYQAASPDEEALVAAARNFGYVFLSRTQDTITLVELGEER--VYQVLAMMDFNSVRKRMSVLVRNP------EGSICLYTKGADTVILERLH-----------HKGV-MEATTEEVLAAFAEQTLRTLCLAYKDVAEDAYKEWEPEHQEAALLLQNRAQALHQVYNKLEQNLQLLGVTAIEDKLQDGVPETIRCLKKGNIKMWVLTGDKPETAVNIGFACQLLSENMSILEDKDIKGLLENYWDENEHQRAFQTMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEATQEPGVSALDFLQARRISQMWRNFGTTMATSQSDASKTRESPEER-RER-AFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRICKFLRYFFYKTVASMMAQIWFSLFNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYTAGQKDELFNYSIFVQAIAHGTITSLINFFVTI-LVSYDMTK--TGSSP-DYQSFGVLVAISSLLSITLEVILVVKYWTLLFVGTVVVSLSSYVIFTSLTESLLLFRISPKTFPFLFADYNVIREPSSLLVIVLNVTLNTLPMLAVRIIRRTVLK------RHPKKE---EEVPSEELTVEPAMR-LRRGM------------------PARRSSYAFSHHEGYANLITQGTILRRHTHVDEFYGDTACNSPNPSEEDVPWQHKESIFNPRKISILAKKRRQHYGKGSQGEVHPNASSQTTEKQTAINIDNHETKKLPTTTSAMSGQLQVSSSEDQAFYSALSQYSLASRPERMDVRSSSWKGPLLRDSASSRSSHLEVTTQLHSHTSS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q148W0-1", "uniprot_id": "AT8B1_MOUSE", "id": "Q148W0-1", "name": "Phospholipid-transporting ATPase IC", "aln": "-----------------------------------------------------------------------------------------------------------MSTERDSETTFDEESQPNDEVVPYSDDETEDELEDQGSTVEPEQNRVNREAEKKRETFRKDCTWQVKANDRK---------------------------------------------------FHEQPHFMNTKFFCIKESKYASNAIKTYKYNGFTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK-------------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWKNQS------FPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFIVLILVSAGLAIGHAYWEAQVGNYS--WYLYDGENA--TPSYRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG------------------------------------------------------------------------DHRDASQHSHSKIELVDFSWNTFADGKLAFYDHYLIEQIQSGK--------EPEVRQFFFLLSICHTVMVDRIDGQ---------------------------------------------------------------------------------------------------------------------INYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGSER--TYNVLAILDFNSDRKRMSIIVRTP------EGSIRLYCKGADTVIYERLH-----------RMNP-TKQETQDALDIFASETLRTLCLCYKEIEEKEFTEWNNKFMAASVASSNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLH----TRMENQRNRGGVSAKFAPPVYEPFFPP-----GENRALIITGSWLNEILLEK-KTKRS----KILKLKFPRTEEERRMRSQSRRRLEEK-KEQ-RQK-NFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKRFFVSLLHGVLTSMVLFFIPLGAYLQTVGQ--DGEAPSDYQSFAVTVASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKR---LKAEEQ---WKRRQSVFRRGV------------------SSRRSAYAFSHQRGYADLISSGRSIRKK---------------------------------------------------RSPLDAIIADGTAEYRRTVES------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFK0-1", "uniprot_id": "E7FFK0_DANRE", "id": "E7FFK0-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------MNSRSRADSQGSLDE---PDDEVMPYSDDETDAELED-----ELDQSVDQLPEPETRPAPAVEAGWSVRANDRE---------------------------------------------------YCKRPEFQKKVFLCIKKSRYSGNAIKTYKYNVLTFLPLNLYEQFKRAANLYFLCLLVLQIIPQISTLPWYTTLVPLVLVLGITAIKDLVDDLARHRMDKEINNRKCDVLL-------------------------------------------------------------------------------------------------------------------NGRFVETRWMNLQVGDVVRLHKNDFIPADIMLLSTSNPNSLCYVETAELDGETNLKFKMGLKVTDERLQEEQQLSQFNALVMCEEPNNRLDKFVGTMIWESQS------YALDLDNMLLRGCKVRNTDICHGLVIFAGNDTKIMRNGGKTRFKRTRIDKLMNYMVYTIFVLLVLLCAGLAIGHTYWYESIGSKA--WYLIDGLDY--TSSYRGFLSFWGYIIILNTMVPISLYVSVEVIRLGQSKFINWDLQMYYADKDTPAKSRTTTLNEQLGQIEYIFSDKTGTLTQNIMAFKKCTISGRTYG------------------------------------------------------------------------EPTTADGVSLDRGKPVDFSWNKYADRKFQFEDHFLISCIRSKK--------DPQVLEFFKLLSLCHTVMVEEKEGE---------------------------------------------------------------------------------------------------------------------LVYQAASPDEGALVTAARNFGFVFLSRTQDTITIQEMDKPQ--TYTMLALLDFNSDRKRMSIILKFP------DGRIRLYCKGADTVIYQRLS-----------PQSK-NKENTQEALDIFANETLRTLCLCYKDISQEEFDRWSRKHQTAAVSMVDRERELDEVYEEIEKDLLLIGATAIEDKLQDGVPETIAKLAKADIKIWVLTGDKKETAENIGYSCQLLTDDMKIHYGEDVNVQLR----NRQTQRRTDPQSRNKKQK---ESFFNE-----PGKNALIITGGWLNEILYEK-KKKRRRLRLKKLRLRQNNQQSSSSTAPDSSQPVDDWEKEK-RQE-DFVDMACECSAVICCRVTPKQKANVVSLVKKYKKAVTLSIGDGANDVNMIKTADIGVGISGQEGMQAVMSSDYAFAQFCFLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWFSFFNGFSAQTAYEDWFITLYNVCYSSLPVLLVGLLDQDVNDKLSLRFPKLYLPGQQGALFNYRNFFISLFHGIFTSLMIFFIPYGAFLQTMGQ--DGEAPSDYQSFAVVAASSLIITVNLQISLNTSYWTFVNFFAVLGSIALYFGIMFDIHSAGIHVIFPNTFTFTGAASNALRQPYLWLTIILTVGVCLLPVICIQFLYQTIYPSVGDKVQRNRKK---YELEDEEDERKKRKPTFQRGG------------------RSRRSAYAFSHSRGYADLIASGRSIRQ----------------------------------------------------RPRVRPELRDSIREVPHAENI------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2ANX3-1", "uniprot_id": "A2ANX3_MOUSE", "id": "A2ANX3-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNKKK--LLEVERVVKANDRD---------------------------------------------------YNEK-------------FQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLI-------------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSK------HALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQF--RTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAG--------------------------------------------------------------------EVLDDPIQKKEITKEKEATDFSSKSKSEKTLHFFDQSLMESIELG---------DPKVHEFLRLLALCHTVMSEENSAG--------------------------------------------------------------------------------------------------------------------QLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPV--TYQLLAFLDFNNIRKRMSVIVRNP------EGRIKLYSKGADTILFEKLH-----------PSNEDLQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGEVREELRKAKENLLG-----------------------------------QSTSFSNGHAVYDNKQRLGLDAGAGEAVTGEYALVINGHSLAHALESD-VEN-DLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAE--DGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYP---SLSDQIRRW---QKAQRKKRPLRSRRPQTRRS-------------------SSRRSGYAFAHQEGYGELITSGKNMRAKS-------------------------------------PAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1B0GWR9-1", "uniprot_id": "A0A1B0GWR9_RAT", "id": "A0A1B0GWR9-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNEKK--LLEVERVVKANDRD---------------------------------------------------YNEK-------------FQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDFFRHKSDNQVNNRQSEVLI-------------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAKFDGIVICEAPNNKLDRFSGVLSWKDSK------HTLSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGNSIWESEVGNQF--RTSLFWREGEKSSLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYAAKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAG--------------------------------------------------------------------EVLDDLDQKKEITKKKEAVDFSGKSKSERTLHFFDHSLMESIELG---------DPKVHEFLRLLALCHTVMSEEDSAG--------------------------------------------------------------------------------------------------------------------QLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPV--TYQLLAFLDFNNIRKRMSVIVRNP------EGQIKLYSKGADTILFEKLH-----------PSNEDLLSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSAIAERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDAVFVITGNTAVEVREELRKAKENLLG-----------------------------------QNTSFSNGHAVYENKQRLELDSGAGETVTGEYALVINGHSLAHALESD-VEK-DLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFYCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDVSEQNSMDCPQLYEPGQLNLLFNKRRFFICVAHGIYTSLILFFIPYGAFYNVAAE--DGQHIADYQSFAVTVATSLVIVVSVQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRQFPFVGNARRSLSQKFVWLVVLLTAVTSVMPVVVFRFLKMHLYP---SLSDQIRRW---QKAQRKERPLRSRRPQTRRS-------------------SSRRSGYAFAHQEGYGELITSGKNMRAKS-------------------------------------PAPTSGLEKMLYSNTSWIGNLCKKTTDVVSGFSHDKTVKL------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98199-1", "uniprot_id": "AT8B2_MOUSE", "id": "P98199-1", "name": "Phospholipid-transporting ATPase ID", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MTVPKEIPEKWARAGAPPSWSQKKPSWGTEEERRARANDRE---------------------------------------------------YNEK-------------FQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLI-------------------------------------------------------------------------------------------------------------------NGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELG-DVSQLARFDGEVICEPPNNKLDKFSGTLYWKENK------FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRF--QVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG---------------------------------------------------------------------DVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDSSLLEAVKMG---------DPHTHEFFRLLSLCHTVMSEEKNEG--------------------------------------------------------------------------------------------------------------------ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAI--TYQLLAILDFNNIRKRMSVIVRNP------EGKIRLYCKGADTILLDRLH-----------PPTQELLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHTVLEVREELRKARKKMVD-----------------------------------SSHAVGNGFTYQGNLSSSKLTS-VLEAVAGEYALVINGHSLAHALEAD-MEL-EFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRD--DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKP---DLSDTVRYT---QLVRKKQKAQHRCMRRVGRT-------------------GSRRSGYAFSHQEGFGELIMSGKNMRLSS-------------------------------------LALSS---FSTRSSSSWIESLRRKKSDSANSPSGGAEKPLKG----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJC6-1", "uniprot_id": "A0A8I6GJC6_RAT", "id": "A0A8I6GJC6-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------MLSRTVGRPSFPLRVSHGLLEPCWVRWHCVQKSAPQATLRPRTVNAPFKNGIMTVPKEMPEKWARAGAPPSWSQKKPSWGTEEERRARANDRE---------------------------------------------------YNEK-------------FQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNSRHSQVLI-------------------------------------------------------------------------------------------------------------------NGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETSELDGETNMKVRQAIPVTSELG-DISQLAKFDGEVICEPPNNKLDKFSGALYWKGNK------FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRF--QVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG---------------------------------------------------------------------DVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKMG---------DPHTHEFFRLLSLCHTVMSEEKNEG--------------------------------------------------------------------------------------------------------------------ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTVTVHELGTSI--TYQLLAILDFNNIRKRMSVIVRNP------EGKIRLYCKGADTILLDRLH-----------PSTQELLNSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKARKKMVD-----------------------------------SSHAVGNGFTYQGNLSSSKLTS-VLEAVAGEYALVINGHSLAHALEAD-MEL-EFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRD--DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTAVCIMPVVAFRFLRLSLKP---DLSDTVRYT---QLVRKKQKAQHRCMRRVGRT-------------------GSRRSGYAFSHQEGFGELIMSGKNMRLSS-------------------------------------LALSS---FSTRSSSSWIESLRRKKSDSANSPSGGAEKPLKG----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3FIN4-1", "uniprot_id": "AT8B5_MOUSE", "id": "A3FIN4-1", "name": "Phospholipid-transporting ATPase FetA", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MKYVKAFVSEISWDCSWYCSAMQERRNEDRQKEEEERILQANNRR---------------------------------------------------FNSL-------------FEYPDNSIKTSKYGFFNFLPMNLFEQFQRLANAYFLILLFLQLVPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHRSDQQINNRSVSILV-------------------------------------------------------------------------------------------------------------------NGRVEEIKWRNVQVGDIIKLENNHPVTADMLLLSSSEPYGLTYIETADLDGETNLKVKQAISVTSAMEDNLELLSSFNGEVRCDPPNNKLDKFSGTLSYLGNT------YLLNHERLLLRGCVIRNTDWCYGLVVYTGQDTKLMQNSGRSTFKRTHIDHLMNVLVVWIFMFLGGMCFLLSIGHGIWENSRGYYF--QAFLPWKHYITSSATSSALIFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNMPAQARTTTLNEELGQVQYVFSDKTGTLTENVMIFNKCSINGKTYG---------------------------------------------------------------------YSYDDNGEYVPKSPKDK-VDFSYNHLADPKFSFYDKTLVEAVKSE---------DPLVYLFFLCLSLCHTVMSEEKVEG--------------------------------------------------------------------------------------------------------------------ELVYQAQSPDEGALVTATRNFGFVFCSRTPETITVIEMGKIR--VYRLLAILDFSNERKRMSVIVRTP------EDRVMLFCKGADTIIYELLH-----------PSCASLSEVTMDHLDDFASEGLRTLMVAYRELDKAYFQTWIKKHGEAWLTLENRERKLALVYEEIERDLMLLGATAIEDKLQRGVPETIVTLSKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDGVFMVEGTDRETVLEELRTARKKMKP-----------------------------------ESLLESDPINMYLARKPKMPFKSLDEVANGNYGLVISGYSLAYALEGS-LEF-ELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDISMIKAAHIGVGISNQEGMQATLSSDFSFCQFHFLQRLLLVHGRLSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPVLGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFVKCLLHGIYNSFVLFFVPMGTVFNSERN--DGKDISDFQSFSLLVQTTLIGVMTMQIALRTTSWTMINHTFTWGSLGLYFCILILLCSDGLCLRYPSIFNFLGVARNSLSQPQIWLCLILSTILCMIPLIGYNFLRPLLWP---INADKVLNR---IHFCLKHPIPTQVQTKIKHP-------------------SLRRSAYAFSHKQGFGALITSGKTLKSSA-------------------------------------LAKSKRFL--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R7E2-1", "uniprot_id": "M0R7E2_RAT", "id": "M0R7E2-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MKYVKAFISEILWDCSWFCSAMYERENEQRQNEEEERILQANNRR---------------------------------------------------FNSL-------------FEYPDNSIKTSKYSFFNFLPVNLFEQFQRLANAYFLILLFLQLIPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHQSDQQVNNRSVLILV-------------------------------------------------------------------------------------------------------------------NGRIEENKWRNVQVGDIIKLENDHPVTADVLLLSSSEPYGLTYIETADLDGETNLKVKQAVSATSDMEDNLELLSAFNGEVRCEPPNNKLDRFSGTLSYLGDT------YFLDYERLLLRGCIIRNTDWCYGLVVYTGPDTKLMQNSGRSTFKRTHIDHLMNVLVLWIFMLLGGMCFLLSIGHGIWESNRGYHF--QAFLPWERYITSSAASSALAFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNTPAQARTTTLNEELGQVEYVFSDKTGTLTENVMIFNKCSINGKTYG---------------------------------------------------------------------YSYDENGQCVPKSPSNK-VDFSYNHLADPKFSFYDKTLVEAVKSE---------DPLVYLFFLCLSLCHTVMSEEKVEEVRRGHQSPGTVLLP------------------------------------------------------------------------------------------------FSLLSGELVYQAQSPDEGALVTASRNFGFVFHSRTPETITVIEMGRVR--VYRLLAILDFSNERKRMSVIVQTP------EDRVMLFCKGADTIIYELLH-----------PSCAALSDVTMDQLDDFASEGLRTLMVAYRELDKAFFQTWIKKHGEAWLTLENREKKLALVYEEIERDLVLLGATAIEDKLQSGVPETIVTLNKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDAVFMVEGTDRETVLEELRTARKKMKP-----------------------------------ESLLESDPINIYLARKSKMPFKAVDEVPNGSYGLVISGCSLAYALESN-TEF-ELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDIGMIKAAHIGVGISGQEGMQATLSSDFSFCQFRYLQRLLLVHGRWSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPILGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFIKCLLHGIYSSFVLFFVPMGTVFNSERS--DGKDISDFQSFSLLVQTTLIWVMTMQIALSTTYWTMINHAFTWGSLGLYFCILFLLCSDGLCLMFPSVFNFLGVARNGLNQPQMWLCLVLSSVLCLIPLMGYNFLKPILWP---INVDKVLNR---IHFCLKHPLPPPVQIKVKHP-------------------GLRRSAYAFSHKQGFGALITSGKTLKSRA-------------------------------------FTRR------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "---------------------MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGGFEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCS-KIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQ-KPRS--RDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVE----------------------------------------------SEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDH----QQKCCEHFLLALALCHSVLVEPNKDDPK------------------------------------------------------------------------------------------------------------------KLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQK--EFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR---------TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVT------------------------------------KYLREKFGMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGE-EMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSS------SSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIR------------------PLTDFKEPISLDTHFDGVSHSQETIVTEEIP------------------------------------MSILNGEQGSRKGYRVSTTLERRDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8K2X1-1", "uniprot_id": "AT10D_MOUSE", "id": "Q8K2X1-1", "name": "Phospholipid-transporting ATPase VD", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTELLQWARHHWRRLSHGRAQGEDERPYNYASLLACGGKSSRTPRPAG-------------------------------------------------KHRVVIPHLQCFKDE--YERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSR-----------------------------------------------------------------------------------------------------------------KEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEK-FSSRIECESPNNDLSRFRGFLEHANKER-----VGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENML-FFNIPEPDGRVISPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDTLGGSLSN--MARPRAQGCRTVPSGPLG-KPSAQLSGSTSAVGNGEGSGEVPHSRQAAFSSPMETDVVPDTRLLDKFSQLTPQLLTG--LDGTAQSSPLETLYIMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRR-SSSPSLASGKDSSSGTPCAFVSRISFFSRPKLSPPMEDESSQMDEIPQASN-SACCTETEAQNRAVGLSVSSAEALSGPPPSASNLCYEAESPDEAALVYAARAYRCTLQSRTPEQVMVDFAALGS-LTFQLLHILPFDSVRKRMSVVVRHPL-----SKQVVVYTKGADSVIMELLS-VAASDGTNPE-QQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQKRAQ------------------------------------VSPELASSRKNFPQPSDA----QGQG-RAGLVITGKTLEFALQES--LQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHHHVLTLPIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDID---------IFTFGNPLNTAALFIILLHLVIESKSLTWIHMLVTVGSILSYFFFALAFGALCVTCNPPSNP--YGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRAKYFDRL----PPEERAEALKRWRG--------------------------TAKVNHVASKHASQSAAMSGR-------------------------------------------PTPGSSAVLAMKS---------ATVST--------VEQ-STR---ETALDRG-----------------CSEPGASKMTGSSAS----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN41-1", "uniprot_id": "D3ZN41_RAT", "id": "D3ZN41-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTELLRWARHHWHRLMNGRTQGDDERSYNYSSLLACGGKSPQTPRPAG-------------------------------------------------KHRVVIPHLQGFKDE--YERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSR-----------------------------------------------------------------------------------------------------------------KEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEK-FSSRIECESPNNDLSRFRGFLEHSNKER-----VGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENML-FFNIPEPDGRVLSPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVEFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDTLSGSLSLGSVARPRAQSCRTAHSRLPG-KPLAQLSGSTSAVGNGEGSGEVLHSRQAAFSSPIETDVVPDTRLLDKFSQITPQLFTR--LDGAAQSAPLETLYIMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRR-SSSPSLASGKDSTSGTPCAFVSRISFFSRTKLSPPVEDESSQMDEIPQASN-SACCTESEAENSDVGLPIDSAEALDGPPPLASNLCYEAESPDEAALVYAARAYHCTLRSRTPEQVVVDFAALGP-LTFQLLHILPFDSVRKRMSVVVRHPL-----SKQVVVYTKGADSVIMELLS-VASSDGTNLEDQQMVIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSEDACGMLMSAILEELQKRTQ------------------------------------VSPELASPRKNFPQPPDP----QVPG-RAGLVITGKTLEFALQES--LQKQFLELTAWCQAVICCRATPLQKSEVVKLVRNHLHVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYQSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDID---------IFTFGNPLNTAALLIILLHLVIESKSLTWIHMLVIVGSILSYFFFALAFGALCVTCNPPSNP--YGIMQKHMLDPVFYLVCVLTTCVALLPRFVYRVLQGSVFPSPILRAKYFDRL----SPEERAEALKRWRG--------------------------TAKVNHVASKYASQSAAKSGR-------------------------------------------PRPGPS--VAMKS---------ATVCT--------IEQ-STR---ETVLDLG-----------------YSKPGASTMTEPLAS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P241-1", "uniprot_id": "AT10D_HUMAN", "id": "Q9P241-1", "name": "Phospholipid-transporting ATPase VD", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTEALQWARYHWRRLIRGATRDDDSGPYNYSSLLACGRKSSQTPKLSG-------------------------------------------------RHRIVVPHIQPFKDE--YEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSR-----------------------------------------------------------------------------------------------------------------KEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEK-FSSRIECESPNNDLSRFRGFLEHSNKER-----VGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMH-FFNVPEPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDTVSGSLSN--MAKPRAPSCRTVHNGPLGNKPSNHLAGSSFTLGSGEGASEVPHSRQAAFSSPIETDVVPDTRLLDKFSQITPRLFMP--LDETIQNPPMETLYIIDFFIALAICNTVVVSAPNQPRQKIRHPSLGGLPIKSLEEIKSLFQRWSVRR-SSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQVCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQP-LACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGP-LTFQLLHILPFDSVRKRMSVVVRHPL-----SNQVVVYTKGADSVIMELLS-VASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQ------------------------------------ALPEQVSLSEDLLQPPVP----RDSGLRAGLIITGKTLEFALQES--LQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTD---------IFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNP--YWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRAKHFDRL----TPEERTKALKKWRG--------------------------AGKMNQVTSKYANQSAGKSGRR------------------------------------------PMPGPSAVFAMKS---------ASSCA--------IEQ-GNLSLCETALDQG-----------------YSETKAFEMAGPSKGKES-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AWN4-1", "uniprot_id": "AT10B_MOUSE", "id": "B1AWN4-1", "name": "Phospholipid-transporting ATPase VB", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTCSLDFSWLRWKWRTQ---DGFSQSPSETTPLLSP--ETDRQSHNTA-------------------------------------------------EQRVVYPNNSMCHQD--WKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYER-----------------------------------------------------------------------------------------------------------------KEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEH-FHSTIVCEKPNNHLSKFKGYMEHPDQTR-----TGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHP-PFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPR-WAQGSTTMRSQGGAQPLRRCHSARVPIQSHCRQRSVGRWETSQP-PVAFSSSIEKDVTPDKNLLSKVRDAALWLETS--DTRPAKPSHSTTASIADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQQLFQRLKLL--SLSQSFSSTAPSDTDLGESLGPNLPTIDSDEKDD--TSVCSG-DCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQGIC-LTFDLLFTLGFDSVRKRMSVVVRHPL-----TDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHE------------------------------------PQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQGK--LENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDID---------VFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNP--YWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKL----PIDKRNLEIQNWRSKQRPAPASASASASAPATGTVHTRPPCHPVPPEAQQNFGASTSKSSGP------------------------------------------PRQKHVEDRVLQDPRCSREHSRDDTCT--------VDTLAKLSSGECLLDPNRTVAPTAYSRGQKDVSRHSSKGSHRRSQSSLTI---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4W5-1", "uniprot_id": "D4A4W5_RAT", "id": "D4A4W5-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTFSLDFSWLRWKWRSQ---NGFSQSPSETTPLLSP--ETGRQSYNPT-------------------------------------------------EQRVVYPNNSMCHQD--WKKVSRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLLVIMVKDGTEDFKRYCFDREMNSASIQIYER-----------------------------------------------------------------------------------------------------------------KEQSYMQKRWQDVRVGDFVQMRCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQQEVQFQPEH-FHSTIVCEKPNNHLSKFKGYMEHPDETR-----TGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHP-PFDVPDADGNFLSPALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGNEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPR-WTQGPATIRSQGGAQPLRRCHSARVPIQSHSRQRSVGRWETSQP-PVAFSSSIEKDVTPDKNLLSKVRDAALWLETL--DTRPAKPSHSTTASIADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQHLFQRLKLL--SLSQSFSSTAPSDTDLGESLGPNVPTIDADEKDD--ASVCSG-DCSTDGGYRSSTWEQGDNLGSESGTSLEEGLEAPALSLDGPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQGIC-LTFDLLFTLGFDSVRKRMSVVVRHPL-----TGEIVVYTKGADSVIMDLLEDPACGNDIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVNEEDFQRWASFRREAEASLDNREELLMETAQHLENRLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNVAHSCKLLDQADTVYSINTENQETCESILNCALEDVKRFHE------------------------------------PQQPARKLCGYCIPSKKPSVNLGAMAPEIGLVIDGKTLNAIFQGK--LENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIVFGILDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDID---------VFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNP--YWLMERQLSDPMFYLTCLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKL----PIDKRNLEIQNWRSKQRPTP--ASASAAAPATGTVHTQPPCCPVPPEAQQDFGASTSKSSSP------------------------------------------PRQKQVEDWVLQGPRCSREHSKDDTCS--------RDTLAKLSSGECLLDPNRTVAPTAYSRGQKDASRHSSKGSHRRSQSSLTI---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94823-1", "uniprot_id": "AT10B_HUMAN", "id": "O94823-1", "name": "Phospholipid-transporting ATPase VB", "aln": "--------------------------------------------------------------------------------------------------------------------------------MALSVDSSWHRWQWRVR---DGFPHCPSETTPLLSP--EKGRQSYNLT-------------------------------------------------QQRVVFPNNSIFHQD--WEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYER-----------------------------------------------------------------------------------------------------------------KEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL-FHNTIVCEKPNNHLNKFKGYMEHPDQTR-----TGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHP-PFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSAR-WAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQP-PVAFSSSIEKDVTPDKNLLTKVRDAALWLETLS-DSRPAKASLSTTSSIADFFLALTICNSVMVSTTTEPRQRVTIKPSSKALGTSLEKIQQLFQKLKLL--SLSQSFSSTAPSDTDLGESLGANVATTDSDERDD--ASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTC-LTFSLLCTLGFDSVRKRMSVVVRHPL-----TGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRE------------------------------------LQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGK--LEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID---------VFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNP--YWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKAQKIDKL----PPDKRNLEIQSWRSRQRPAP--------VPEV----ARPTHHPVSSITGQDFSASTPKSSNP------------------------------------------PKRKHVEESVLHEQRCGTECMRDDSCS--------GDSSAQLSSGEHLLGPNRIMA---YSRGQTDMCRCSKRSSHRRSQSSLTI---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54827-1", "uniprot_id": "AT10A_MOUSE", "id": "O54827-1", "name": "Phospholipid-transporting ATPase VA", "aln": "----------------------------------------------------------------------------------------------------------------------------MERELPAAEESASSGWRRPRRRRWEGRTRTVR--SNLLPPLGTEDSTIGAPK-------------------------------------------------GERLLM------------RGCIQHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSR-----------------------------------------------------------------------------------------------------------------EEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNNDLSRFRGYIMHSNGEK-----AGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGT-------ISHRGSTGSHQSIWMTHKTQSIKSHRRTG--SRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASGCSSIGNLSTSKSSHKSGSAFLPSL---SQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASEC--TTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPL-----TDEINVYTKGADSVVMDLLL--PCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPR----------------------------------STLQNSESNLSVGFS-FNPVSTSTDASPSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVD---------VFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNP--YWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLGRQLAKK----PLNKFSDPKETFAQGQPPGHSETELSERKTMGPFETLPRDCASQASQFTQQLTCSPEASGEPSAVDTNM-----------------------------------PLRENTLLEGLGSQASGSSMPRGAIS---EVCPGDSKRQSTSASQTARLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSGSSLQMDKQDGEFLSNPPQPEQDLHSFQGQVTGYL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JWQ8-1", "uniprot_id": "A0A0G2JWQ8_RAT", "id": "A0A0G2JWQ8-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------------------------------MERESAAAEEPASPGRRRPRRRRWEGRTRTVR--SNLLPSLGTEDSTAGASK-------------------------------------------------GERLLM------------RGCIQHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPVLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSR-----------------------------------------------------------------------------------------------------------------EEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNNDLSRFRGCIIHSNGEK-----AGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFLTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLAKYQEADSEEEEMVSKVGP-------ISHRGSTGSHQSIWMTHKTQSIKSHRRTG--SRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLSIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRKFTPSRLASGCSSIGNLTNNKSSNKSGSTFLPSL---SQDNMLLRLEERLGQTAPVIASNGYASQASQAESWTSEC--TSEQKCPGDQREQQEGELRYEAESPDEAALVYAAKAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPL-----TDEINVYTKGADSVVMDLLL--PCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAETSVESREELLFQSAVRLETNLHLLGATGIEDRLQDGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSREACAALLDQCLCYVQSRNSR----------------------------------SVPQNSESSFSVGFS-FNPASTSTDSSPSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRNKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLRKPQLYKSGQNMEEYSPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVD---------VFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNP--YWTMPTLLGDPLFYLTCLIAPVAALLPRLFFKALQGSLFPTQLQLGRQLAKK----SLNKFSVPKETFAQGQPPGHTEPELSERKAMGPFESLPRDCASQASQFTQQLACSPEASGEPSAVDTNM-----------------------------------PLRENTLLEGLGSQASGSAMPREAIS---EDCPGDSKRKSTSASQTAPLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSRSSLQMDKQDGEFLSNPPQPDQDLHNLQGQVTGYF---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60312-1", "uniprot_id": "AT10A_HUMAN", "id": "O60312-1", "name": "Phospholipid-transporting ATPase VA", "aln": "----------------------------------------------------------------------------------------------------------------------------MEREPAGTEEPGPPG----RRRRREGRTRTVR--SNLLPPPGAEDPAAGAAK-------------------------------------------------GERRRR------------RGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSR-----------------------------------------------------------------------------------------------------------------EEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNNDLSRFRGCIIHDNGKK-----AGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGS-------VSQRGSIGSHQSVRVVHRTQSTKSHRRTG--SRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTP---SSDGMLLRLEERLGQPTSAIASNGYSSQADN---WASEL--AQEQ--------ESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPL-----TDEINVYTKGADSVVMDLLQ--PCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQ----------------------------------RAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKN--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVD---------LFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNP--YWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRK----SPRRCSAPKETFAQGRLPKDSGTEHSSGRTVK--TSVP---LSQPSWHTQQPVCSLEASGEPSTVDMSM-----------------------------------PVREHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKVRAASTGRVTPLSSLFSLPTFSLLNWISSWSLVSRLGSVLQFSRTEQLADGQAG--RGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTG6-1", "uniprot_id": "Q7KTG6_DROME", "id": "Q7KTG6-1", "name": "Phospholipid-transporting ATPase", "aln": "MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDG-----------------------------------------------------------------------------------------------------------------ETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSK-FVSRVEADAPTTKLYRFHGALIHPTGER-----VPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFP----VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPP------------SELEKIYSKPGAP-------APPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSP----------PMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIG-----SQEIVLYTKGADSSIMPVLV--PCSHN----SPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDME-----------------------------------------NDKTTSTLGYGQSLRKK---------QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVG---------IWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSS--YWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKR----ERSRGEALLVTWSR-----------------------------------STSASSIYR-------------------------------------------------------------------------------------------------------------------ITDYGSKNQIITTIT----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** ..*.* *: *::. :* **: : .* . . *: :. : :* :* : * :* : * :: ***.: : : ..**::** ::: . :::* :***:*:* : : : .: * : : * : . ::** . ::**. *:*:::* :** : * . *:: :. * : . * : . . * .:: . ::*::::: *. : : : :: :: .: :.***:.::*:*******:* * *.:* : * * . : : : : * :. **** *** :: : . : : : :* : *.. ** ** ::: : ****: : * * * :* ** * :. : : : * . : :* : *:* *.:**:** ** ::* * . :.:*:***** *** *:..:..:: . :: * *:*** :* **: :* :*: **.****:**: **: *.:*:*::.:** **. :*: . :* .: :*:: ** .* *:..:: ::**. :*: : .:.. : : ::*: ::: * : .: :: : : * ** * : * : .. *. * .. . : . : . * : : : . : :* : ", "identical_positions": 162, "similar_positions": 238, "identity": "8.37%" }, { "cls_id": "homologset.agr.SGD:S000002503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LS62-1", "uniprot_id": "F1LS62_RAT", "id": "F1LS62-1", "name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "aln": "--MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVT----GQSGLFTQYNIQ-KKPMTVKEFRQLANSSKYCTPR----------------------YLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRRKKLRKAP--------KSLQGNK----------------------SLSKRPKAEEDEEFAEFI-GEEVSSPAVCPRHLKVTEKPEK-FKLANIGASSE--KEASDTRIQVDQSLTN---DTKLSGKSCINSSVIDEIQPENDTANAVTS-PSTLKKASDLIPFSHGHITGKESRLLKILQLESPKIPSSLAE--------SNRVLTEGEENDEEGHASNLEP--------------GEVPDAL----------------SEE--RNGLNVPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLMPYYK---PDNSKEENDSRWETAVNEVVQSGRKTKPIIPEMCFIYSEENVEYSPPNAFLEEDGTSLL---ISCSKCFVRVHASCYGVPSHEVCDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNQWAHVICAVAVPEVRFTNVPERTQIDVDRIPLQRLKLKCIFCRQRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHRVNSNVKSKTCEKAISVGQTVITKHRNTRYYSCRVIDVTSQIFYEVMFDDGSFSRDTFPEDIVSRNCVKLGPPAEGEVIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADVIQGERKRQRVLSSRLKNEYVDDPVYRTFLKSSFQKKCQKRQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCD7-1", "uniprot_id": "KDM4C_MOUSE", "id": "Q8VCD7-1", "name": "Lysine-specific demethylase 4C", "aln": "--MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVT----GQSGLFTQYNIQ-KKAMTVKEFRQLANSSKYCTPR----------------------YLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRKKKLRKPP--------KSLQGNK----------------------PLCKRPKPEEDEEFAEFS-GEEGANPAMGPRHLKVTEKPEKALKLGKLEESSA--KEALDTRIQVDQSLLN---DTKLSGKGCISSSVTAEIPPEDNRASAVIS-PSQLKEGADCIPLSHGHQAGKESHLLKILKLESPKIPSPLPE--------SNKVLTEGEENDEEGHGSNLEP--------------GEIPEAL----------------SEE--RNGLNIPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLMPYYK---PDSSKEENDSRWETAVNEVVQSGRKTKPIIPEMCFIYSEENVDYSPPNAFLEEDGTSLL---ISCAKCFVRVHASCYGVPSHEVCDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNQWAHVICAVAVPEVRFTNVPERTQIDVDRIPLQRLKLKCIFCRHRVKKVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHRVNSNAKSKTCEKAISVGQTVITKHRNTRYYSCRVIDVTSQTFYEVMFDDGSFSRDTFPEDIVSRNCVKLGPPAEGEVIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADVIQGERKRQRVLSSRLKNEYVDDPVYRTFLKSSFQKKCQKRQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3R0-1", "uniprot_id": "KDM4C_HUMAN", "id": "Q9H3R0-1", "name": "Lysine-specific demethylase 4C", "aln": "--MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNL---LIPAPIQQMVT----GQSGLFTQYNIQ-KKAMTVKEFRQLANSGKYCTPR----------------------YLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKAS--------RSFQCAR----------------------STSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSE--EESSASRMQVEQNLSD---HIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSISSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAE--------SNGVLTEGEESDVESHGNGLEP--------------GEIPAVP----------------SGE--RNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHK---PDSSNEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLL---ISCAKCCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW72-1", "uniprot_id": "KDM4A_MOUSE", "id": "Q8BW72-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-TSYDDIDDL---VIPAPIQQLVT----GQSGLFTQYNIQ-KKAMTVREFRKIANSDKYCTPR----------------------YSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEE-CPEEDVEAADQGEE----------------------GDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPS---------VKKKRSAPRSI----------------SEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHP--LVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQ---VEFG---AFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSML---VSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5I7-1", "uniprot_id": "A0A0G2K5I7_RAT", "id": "A0A0G2K5I7-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-TSYDDIDDL---VIPAPIQQLVT----GQSGLFTQYNIQ-KKAMTVREFRKIANSDKYCTPR----------------------YSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSTVIDHTLPTPEAAEFLKDSG-LTPRAGNEE-CPEEDSEAAEQGEE----------------------GDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECQATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEDEEPEAAALDLSVNPESVEGRLVFSGSKKKASSSLGSSSSQDSVSSDSETTESVSCQGQEKT-VLTVHSYSRGDGKAAPGEPS---------VKRQRSAPRSI----------------SEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHP--LVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNELMAQQAPHCAVCMIFQTYHQ---VEFG---GFSQSCGNASEPAAQPQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSML---VSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75164-1", "uniprot_id": "KDM4A_HUMAN", "id": "O75164-1", "name": "Lysine-specific demethylase 4A", "aln": "----MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPR-ASYDDIDDL---VIPAPIQQLVT----GQSGLFTQYNIQ-KKAMTVREFRKIANSDKYCTPR----------------------YSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESE-LPPRAGNEEECPEEDMEGVEDGEE----------------------GDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPC---------TRKKGSAARSF----------------SERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQ---VEFG---GFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSIL---VSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYREDYIEPALYRAIME-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VY5-1", "uniprot_id": "KDM4B_MOUSE", "id": "Q91VY5-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVT----GQSGLFTQYNIQ-KKAMTVGEYRRLANSEKYCTPR----------------------HQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKLLRRQISVKESRPWRKAEEERR------REPTRRPGPASHRRRSQPKKSKPEESRSPGEATAGVSTLDEARGCSRGEA----MPEDEEEEELLPSQGHEAEGVEEDGRGKPRPTKARNKKKTPSP-SSPPLLSAPPALFPTEEVLRPPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQ---------------LAPMEL-GPEE----------ENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-AFLFSGEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTER---------DSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPL---ISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRAS--GAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RB75-1", "uniprot_id": "M0RB75_RAT", "id": "M0RB75-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVT----GQSGLFTQYNIQ-KKAMTVGEYRRLANSEKYCTPR----------------------HQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRET----MPEEEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKKTPSL-LSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQ---------------LAPMEL-GPEE----------EDQAQAGDSQGTTSFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-AFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFYPYSQSVQTEREVLATPG--DSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPL---ISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRAS--GAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDGVKAAKRPRVATVLATTTEDTGRSPEYLAFMESLLQAQGQPGAPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94953-1", "uniprot_id": "KDM4B_HUMAN", "id": "O94953-1", "name": "Lysine-specific demethylase 4B", "aln": "---MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPR-QTYDDIDDV---VIPAPIQQVVT----GQSGLFTQYNIQ-KKAMTVGEYRRLANSEKYCTPR----------------------HQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKLLRR----------------------------------SHRKRSQPKKPKPEDPKFPGEGTAGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVLGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGKAAFNQEHVSCQQAFEHFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-ASPFSGEEDVSDPDALRPLLSLQWKNRAASFQAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIASLGKGCPATLPSKSRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPL---IACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHKSG--GHAVQLLRAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGSYSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAKRPRVGTPLAT--EDSGRSQDYVAFVESLLQVQGRPGAPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V333-1", "uniprot_id": "KDM4A_DROME", "id": "Q9V333-1", "name": "Probable lysine-specific demethylase 4A", "aln": "MSTRSSFADEEQNKVPRIMTFRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVPRKSGY-DIDNIN-MTIPAPICQVVT----GAHGVYQQINIQQRRQMTLRQFMEKANSELHQTPR----------------------HFDYDDLERKYWKNITYISPLYAADVKGSLSDEDLDVWNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYSINYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYNKITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCRSDMVKISMETFVRRFQPERYDNWLKGQD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCHP--------------------------------------------------------------EEP-GKICAAAP------------------------------------------PTLNEYEKQENLRA----------------------------------AKSEEESPQKRGCSLAG----------------------NGCERN---AES---------------AEDVDD-----KASVSSYSSC--------RQLQPVVKLRKLPTIASVPEPSS----------------APKRYDFN-TEAVVRVKR--------LWN------ELPCPDRG---------------------------ANLLTNGVVKNTKRMRFQTK-----------------VLTLDDED----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V6L0-1", "uniprot_id": "KDM4B_DROME", "id": "Q9V6L0-1", "name": "Probable lysine-specific demethylase 4B", "aln": "---------MKMSEVPRIKVFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPEWVPRRSGYADLDALN-VTIPAPICQVVT----GKQGYYQQINIQ-KKPLTVKQFSELASTERYATPK----------------------HFDFEDLERKYWKNITYVAPIYGADVSGSITDTDQDSWNINRLGTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQHDVPVSKITQEAGEIMITFPFGYHAGFNHGFNCAESTNFAMERWIEYGKRAVQCTCSNDMVKISMDTFVKRFQSDRYDLWMEGRD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGRHP--------------------------------------------------------------EDPPNAVLSAAPLPPHLDVLLCDKKMKKQCNPTKAKS------------FKERNPDLDLDEIQQNPNVPDDVKAMLKESVLTLDT--------------GDLATDEADFPNEDAMSLQSPANLKTKQELLEYI-------DDGTEDD---DEEEDFKRRKQKRRY---DADYDDDWLASKRKTNSRNNR--------GRSPRTKDDRSISPASSTSSTSR----------------GARRGKASGTPRKTPARR--------KKDSITTSPAVSSAATA---------------------------VKTPTSAVVAGTTSIATTTT-----------------PPADGGGGESSSLGSHCTTASP--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A1W2PPD8-1", "uniprot_id": "KDM4F_HUMAN", "id": "A0A1W2PPD8-1", "name": "Probable lysine-specific demethylase 4F", "aln": "---MKSVHSSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKAR-QMYDDIEDI---LIATPLQQVTS----GQGGVFTQYHKK-KKAMRVGQYRHLANSKKYQTPP----------------------HQNFADLEQRYWKSHPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNWR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIALRR---------------------------------------------------------AALGLRHLRNHITSCPTRTVAPRLCYNPKG------------------------GGTDAVPGSAIQALETSAWVLPPSTGRWGPCRGCGR-----------------GRGRGRGRGRRPRELGTEETTVQSAAKRRLSVGTGSRAPGRKPQL---QFADEALTDKPAPLSGGLPHFAKASGCCCAPDLQP-------------LGPPLDPDEPMHPGPCLLSLDSTASSLPLVVPMTPPSVTVPLITLSRDTGGDWKSPVNLAKVVAMDHSYASRVPVPTKFSR----------------------------ISWAPDSSAGAKARQRYAT--------------EFGDIFLQCMINPLDPWPLNMVSNVK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03833-1", "uniprot_id": "GIS1_YEAST", "id": "Q03833-1", "name": "Transcriptional activator/repressor GIS1", "aln": "------MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENG-IVKVIPPKEWLELLEGSPPAESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQWKNLAESLDSRISQGDFNDKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFYAVDENSSIFPYDLTLWNLNNLPDSINSSNRR------------LLTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYNFGESIEFILDQQAVVRKQPLKCGCGNKKEERKSGPFSNLSYDSNESEQRGSITDNDNDLFQKVRSFDELLNHSSQELQNLEDNK----------------------------------------------------------------------------------------------------------------------------------------------NPLFSNINMNRPQSSSLRSTTPNGVNQFLNMNQTTISRISSPLLSRMMDLSNIVEPTLDDPGSKFKRKVLTP----------------------------------------------------QLPQMNIPSNSSNFGTPSLTNTNSLLSNITATSTNPSTTTNGSQNHNNVNANGINTSAAASINNNISSTNNSANNSSSNNNVSTVPSSMMHSSTLN-------------GTSGLGGDNDDNMLALSLATLANSATASPRLTLPPLSSPMNPNGHTSYNGNMMNNNSGNGSNGSNSYSNGVTTAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKNPLNSGLAPLSPSTSNIPFLKRNNVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSSTINDYSNGTGIRQ---------------------------NSNNINPLDAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQESNPSILNNNTNNNDNYRTSSMNNNGNNYQAHSSKFGE----------NEVIMSDHGKIYICRECNRQFSSGHHLTRHKKSVHSGEKPHSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .* *: ** :* :: : . * . . :.*: ** ** : : : :*: * .. * : : .: : :: . *.: . : ** :**. . *:*..* ..:: **: * :: : * * * *.** :: : ******** ** ** :*. :: : . . . * .::**: : ** .*:: .: .::.* *:::***: ::***:*:* .*: :* : * . * * . . * . . . . . . : : . . . . . . . ", "identical_positions": 66, "similar_positions": 103, "identity": "5.63%" }, { "cls_id": "homologset.agr.SGD:S000002504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0U9-1", "uniprot_id": "D4A0U9_RAT", "id": "D4A0U9-1", "name": "DNA mismatch repair protein", "aln": "MRAPSPRPPTPGHVGGGGPAHRAGRDARGLAAGLRVLGSDAPPPGFPASSGRAADAVPVGARSGGPFGPSAFIMSRQSTLYSFFPKSPALGDTKEAAARASRKG---AAASGASASRGRDAAWSEAGPGSRPAALSTSLPEAKDLNGGLRRSAAPAVPARTQFRNSSSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIRKNGKSARVHVQFFDDSPTRGWVSKRMLKPYTGSKSKEAQKGGHFYSSKSEILRAMQRADEALSKDKAQRLELAVCDEPSEPEEEEEEEEEETQVHGAYLSDKSEEENQDESEEETQPNAQGPRRSSRQVKKRRVISDSESDIGGSDVEFKPDSKQEGSSDEVSSGVGDSDSEGLGSFGKGAPKRKRTVAAHGGLKRKSLKKETGSA-KQATRILSETKSTLSAFCAPQNSESQTHVCGGGNDSSGPTIWYHETLEWLKPEKRRDENRRRPDHPDYNSSTLYVPEDFLNSCTPGMRRWWQFKSQNFDLVIFYKVGKFYELYHMDAVIGVSELGLIFMKG---NWAHSGFPEIAFGRFSDSLVQKGYKVARVEQTETPEMMEARCRKMAHVSKFDRVVRR----EICRIITKGTQTYSVLDGDPSENYSRYLLSLKEKEEDSSGHMRAYGVCFVDTSLGKFFLGQFSDDRHCSRLRTLVAHYPPVQILFEKGNLSTETKTVLKGSLSSCLQEGLIP-GSQFWDATKTLRTLLEGGYFTG--NEGSGAELPPVLKAMTSESDSVGLTPGEESELSLSALGGCVFYLKKCLIDQELLSMANFEEYFPLDSDMVGTVKPGAVFTKASQRMVLDAVTLSNLEIFLNGTNGSTEGTLLERLDTCHTPFGKRLLKQWLCAPLCSPSAISDRLDAIEDLMAVPDKVAEVADLLKKLPDLERLLSKIHNVG-SPLKSQNHPDTRAIMYEETTYSKKKIIDFLSALEGFKVMCKITRLMEDVADGFKSKTLKQVVTLQTKSPKGRFPDLTAELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLDKQRSRIGCRNIVYWGIGRNRYQLEIPENFATRNLPEEYELKSTKKG---CKRYWTKVIEKKLSNLINAEERRDASLKDCMRRLFYNFDKNH-KDWQSAVECTAVLDVLLCLASYSQGGDGPMCRPVLLLPGE-----DTHPFLELKGSRHPCITK-TFFGDDFIPNDILIGCEEDAEADGKAYCVLVTGPNMGGKSTLIRQAGLLAVMAQMGCYVPAELCRLTPVDRVFTRLGASDRIMSGESTFFVELSETASILRHATAHSLVLVDELGRGTATFDGTAIASAVVKELAETIKCRTLFSTHYHSLVEDYSKNVCVRLGHMACMVEN-ECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFERMN--------QALQLFREVCLASE-----------------------------RPTVNSEAIHRLLALVNQL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54276-1", "uniprot_id": "MSH6_MOUSE", "id": "P54276-1", "name": "DNA mismatch repair protein Msh6", "aln": "-------------------------------------------------------------------------MSRQSTLYSFFPKSPALGDTKKAAAEASRQG---AAASGASASRGGDAAWSEAEPGSRSAAVSASSPEAKDLNGGLRRASSSAQAVP-----PSSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIRKKGKSVRVHVQFFDDSPTRGWVSKRMLKPYTGSKSKEAQKGGHFYSSKSEILRAMQRADEALSKDTAERLQLAVCDEPSEPE-----EEEETEVHEAYLSDKSEEDNYNESEEEAQPSVQGPRRSSRQVKKRRVISDSESDIGGSDVEFKPDTKQEGSSDDASSGVGDSDSEDLGTFGKGAPKRKRAMVAQGGLRRKSLKKETGSA-KRATPILSETKSTLSAFSAPQNSESQTHVSGGGNDSSGPTVWYHETLEWLKPEKRRDEHRRRPDHPEFNPTTLYVPEEFLNSCTPGMRKWWQLKSQNFDLVIFYKVGKFYELYHMDAVIGVSELGLIFMKG---NWAHSGFPEIAFGRFSDSLVQKGYKVARVEQTETPEMMEARCRKMAHVSKFDRVVRR----EICRIITKGTQTYSVLDGDPSENYSRYLLSLKEKEEETSGHTRVYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQILFEKGNLSTETKTVLKGSLSSCLQEGLIP-GSQFWDATKTLRTLLEGGYFTG--NGDSSTVLPLVLKGMTSESDSVGLTPGEESELALSALGGIVFYLKKCLIDQELLSMANFEEYFPLDSDTVSTVKPGAVFTKASQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERLDTCHTPFGKRLLKQWLCAPLCSPSAISDRLDAVEDLMAVPDKVTEVADLLKKLPDLERLLSKIHNVG-SPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKVSGLLEEVAGGFTSKTLKQVVTLQSKSPKGRFPDLTAELQRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLDKQRSRLGCKSIVYWGIGRNRYQLEIPENFATRNLPEEYELKSTKKG---CKRYWTKTIEKKLANLINAEERRDTSLKDCMRRLFCNFDKNH-KDWQSAVECIAVLDVLLCLANYSQGGDGPMCRPEIVLPGE-----DTHPFLEFKGSRHPCITK-TFFGDDFIPNDILIGCEEEAEEHGKAYCVLVTGPNMGGKSTLIRQAGLLAVMAQLGCYVPAEKCRLTPVDRVFTRLGASDRIMSGESTFFVELSETASILRHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSKSVCVRLGHMACMVEN-ECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFERMN--------QSLQLFREVCLATE-----------------------------KPTINGEAIHRLLALINGL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52701-1", "uniprot_id": "MSH6_HUMAN", "id": "P52701-1", "name": "DNA mismatch repair protein Msh6", "aln": "-------------------------------------------------------------------------MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTS--------CDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPE-----EEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKG---NWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRR----EICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIP-GSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVG-SPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKG---CKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLP-E-----DTPPFLELKGSRHPCITK-TFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVEN-ECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMN--------QSLRLFREVCLASE-----------------------------RSTVDAEAVHKLLTLIKEL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUM0-1", "uniprot_id": "MSH6_DROME", "id": "Q9VUM0-1", "name": "Probable DNA mismatch repair protein Msh6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MSKKLN-----TSVGGTPTN----------------------------TLLNYFSKSPAFDKKK---LTPSVKTDPDASK----SEKENLQNQQPKVKDGKKE----ASKPAAKRKLPISDDEPASGQRKRKRIVQPESDSEPE---------MEVT------KSEDD----------------------------FSDCASDYEPDENEASDDSVSSG-AEEVSPSENDMSVDSP--TPKKSRKKSKILNNNNNNEPSSKKVKLESTIQLAEGATFQEKLKNLQSNAKQDASYDDIVTNTSN-LDEPVVWPHQKLEFLQPDKIKDKEGRRPDHPDYDKSTLHVPEKFLNGLSPGVRQWWVLKSDNYDCVLFFKVGKFYELYHMDADVGVNELGFTYMRG---EFAHSGFPEISFDKMSTILVDRGFKVARVEQTETPDMMTERCKRIKAT-KFDKVVAR----EICQITNRGTQVFGSQCKIGPNHQPNYMLAIVEKDE---GTCSRYGVCFIDTSIGDFHLGEFEDDKNCSRLLTLVSHHMPVLFLNEKSALSQRTQQIVRTVLGGILKEPVPGNGKHACSAEKTLK-LLAERYYAG---PGSDDNWPLVLRTMQSDMDHLGLTPNDNYKLALKALGQCIFFIHKCKLEPKVLPMARYQLYVPPD--QLADAKPAVASTLRRSHMVLDATTLSNLRIIG------EEHSLLSTLDHCCTKFGKRLLHHWLCAPSCDVSVIKERQDAIGELIRMPTELQEVRALLAPMPDFERNLAQIHLFGNKQIKQMDHPDSRAILFEEKLYNKQKLQGFMAVLKGFNDLTKLP----TMFHQCKTTLLKRITQLPESG--GSFPDLSKELQYFATAFDHDAAAKTGVIAPQAGMDAEYDAAMDSIGEVEKRLKTYLVEQERHFGCR-ITYFGSDKKRYQLDVPESHASKAN-KSYTLEGQTKGKKPSRRYTTAETRALLKDMQHAEDTRNMVLKDLARRLFEKFSNHY-DQWKQCIDCVANLDVLGSLAEYA-GQQMVICVPELVSD-------ADQPFIQLEEGYHPCAN-----ASTYIPNGLELGTASEAPLS------LLTGPNMGGKSTLMREVGLLVIMAQIGAHIPAASCRLSLVDRIFTRLGAQDDILAGHSTFLVELNETSLILKHATCHSLVLLDELGRGTATYDGTAIAASVVNFLAN-LKCRTLFSTHYHNLIDFFHNDKRITLGHMACMVENEDNADPTQETVTFLYKYTAGACPKSYGFNAAKLAGMPQGIIKRAYELSKKVEAIA--------LQRKITAKIVAATAG----------------------------NEDTKKEKINALKDLLKQLKMCQV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03834-1", "uniprot_id": "MSH6_YEAST", "id": "Q03834-1", "name": "DNA mismatch repair protein MSH6", "aln": "-------------------------------------------------------------------------------------------------------------------MAPATPKTSKTAHFENGSTSSQKKMKQSSLLSFFSKQVPSGTPSK--------------------KVQKPTPATLENTATDKITKNPQGGKTGKLFVDVDEDNDLTIAEETVSTVRSDIMHSQEPQSDTMLNSNTTEPKSTTTDEDLSSSQSRRNHKRRVNYAESDDDD-------------------------------------------SDTTFTAKRKKGKVVDSESDEDEYLPDKNDGDEDDDIADDKEDIKGELAEDSGDDD---DLISLAETTSKKKFSYNTSHSSSPFTRNISRDNSKKKSRPNQAPSRSYNPSHSQPSATSKSSKFNKQNEERYQWLVDERDAQRRPKSDPEYDPRTLYIPSSAWNKFTPFEKQYWEIKSKMWDCIVFFKKGKFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVDQRESMLAKEMREGSKGIVKRELQCILTSGTLTDGDMLHSDLATFCLAIREEPGNFYN-ETQLDSSTIVQKLNTKIFGAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVMERNNLSTLANKIVKFNSAPNAIFNEVKAGEEFYDCDKTYAEIISSEYFST------EEDWPEVLKSYYDTGKKVGFS----------AFGGLLYYLKWLKLDKNLISMKNIKEY---------------DFVKSQHSMVLDGITLQNLEIFSNSFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQDITLREQLEITFSKLPDLERMLARIHSRT-----------IKVKDFEKVITAFETIIELQDSLK---------------NNDLKGDVSKYISSFP--------EGLVEAVKSWTNAFERQKAINENIIVPQRGFDIEFDKSMDRIQELEDELMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPIS-ATKNVPSNWVQMAANKT---YKRYYSDEVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRTSEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGKEQP-------RLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFATHYGTLASSFKHHPQVRPLKMSILVDE------ATRNVTFLYKMLEGQSEGSFGMHVASMCGISKEIIDNAQIAADNLEHTSRLVKERDLAANNLNGEVVSVPGGLQSDFVRIAYGDGLKNTKLGSGEGVLNYDWNIKRNVLKSLFSIIDDLQS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* . . * . . : : *. * . : :: :. : .. * .. :: . . . .: : .. * .: * *. . . :: : . * . : . . . . . *: : : . . . . : . . . . :: .: . :* . * ..*::: **::*.. * :* :::* :**. :* :: :* ***:***. ** :. :.: * : :*:**::* : ::: *:***:*:* *: * : : : : . .: . : . : .. :*..*:**: *.: : :*.** .*::: **::: *: .: *:. ** :: ::: . *.. .. ** :: *: * **: . . :*:: *:* ::::: :: :::.* . : * . ****. **.**.*: : :*:. .: . * :***::::** * *..* *:: .*: :: : :**:** *::** :. :*: :.: : *: . * : : .* :: : .**::: * : .:*.*: *:* ::* :: * * *. * * . :: * * * . .:: * :::* . ::: ..: . .* :** : . .: .*:: :. :* .** :*. :: * ::. : :* * .:: : * * :: *:::: *** . .. :***.: :* . *:**.* .****::* . : .:***:*.::*. . *: :**::*****.* *: *.***:*** ** ** ** :**:::****** :: ** *** :*:: :* ::. :*:*** .* . : : : :*: :*:: : ..:***** * . *:*::.* :..:.: :*... : :.* .: :: .. . : :: * ::. * ", "identical_positions": 214, "similar_positions": 374, "identity": "14.18%" }, { "cls_id": "homologset.agr.SGD:S000002505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLZ1-1", "uniprot_id": "GLRX3_RAT", "id": "Q9JLZ1-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAAEAAVAVVEVGSARQFEELLRLK-TKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGSFPPSTNEHVKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQM9-1", "uniprot_id": "GLRX3_MOUSE", "id": "Q9CQM9-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAGEAAVAVVEVGSAQQFEELLRLK-TKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGAFPPSTNEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76003-1", "uniprot_id": "GLRX3_HUMAN", "id": "O76003-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEA--AVAAVEEVGSAGQFEELLRLK-AKSLLVVHFWAPWAPQCAQMNEVMAELAKEL--PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWPTYPQLYVKGELVGGLDIVKELKENGE--LLPILRGEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ54-1", "uniprot_id": "GLRX3_DANRE", "id": "Q5XJ54-1", "name": "Glutaredoxin 3", "aln": "MAN-----------FTDAASLQQFDELLKNN-SKSLTVVHFHAPWAPQCSQMNDVMAELAKEH--KHTMFVKLEAEAVPEVSEKYEITSVPTFLFFKGGEKIDRLDGAHAPELTNKVQRLGSGGGGAVGAGDVPKEDLNQRLKRLINAAPCMLFMKGSPQEPRCGFSRQIIQILKDHNVQYSSFDILSDEEVRQGLKTYSNWPTYPQVYVSGELIGGLDIVKELVESGELENTFPKTVSLENRLKSLINKSPVMLFMKGNKEAAKCGFSRQILEIMNNTGVEYDTFDILEDEEVRQGLKTYSNWPTFPQLYVKGDLIGGLDIVKELLEGGE--LVSVLKGEN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ6-1", "uniprot_id": "Q9VJZ6_DROME", "id": "Q9VJZ6-1", "name": "", "aln": "------------MPVVNVSAAEEYQKYIN---ADKTTVALFAAEWAEQCGQVKDALEELAKITG-EKLQFISLNAEQFPEISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAAATGQT----------------------------------------------------------------------------------------------------------LEERLKALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYETFDILGDEEVRQGLKTYSDWPTYPQVYVKGELIGGLDIIKELLANNE--LESTLKG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03835-1", "uniprot_id": "GLRX3_YEAST", "id": "Q03835-1", "name": "Monothiol glutaredoxin-3", "aln": "------------MPVIEINDQEQFTYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDADENSEISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLEDCKNSVNSGSSQTHTMEN------------------------------------------------------------------------------ANVNEGSHNDEDDDDEEEEEETEEQINARLTKLVNAAPVMLFMKGSPSEPKCGFSRQLVGILREHQVRFGFFDILRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIKESLEEDPDFLQHALQS--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: .. * * : ** * :::.: ::: : *:.::*: .*:* .:* :** .::: . :..:.*.. : .. . . :: **. * * :.:*:****. . .:****:*:: *:.. : : **** **.***.** :*:***:**:*:.*:: *****:** . * *:. ", "identical_positions": 56, "similar_positions": 76, "identity": "16.37%" }, { "cls_id": "homologset.agr.SGD:S000002506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62258-1", "uniprot_id": "1433E_HUMAN", "id": "P62258-1", "name": "14-3-3 protein epsilon", "aln": "MDD-REDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62259-1", "uniprot_id": "1433E_MOUSE", "id": "P62259-1", "name": "14-3-3 protein epsilon", "aln": "MDD-REDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62260-1", "uniprot_id": "1433E_RAT", "id": "P62260-1", "name": "14-3-3 protein epsilon", "aln": "MDD-REDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG-GEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD------GEEQNKEALQDVEDENQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P92177-3", "uniprot_id": "1433E_DROME", "id": "P92177-3", "name": "14-3-3 protein epsilon", "aln": "MTE-RENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIEQKEENKG-AEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYLAEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDGEPKEQIQDVEDQDVS---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34730-1", "uniprot_id": "BMH2_YEAST", "id": "P34730-1", "name": "Protein BMH2", "aln": "MSQTREDSVYLAKLAEQAERYEEMVENMKAVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELIRSYRSKIETELTKISDDILSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNSSLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDISESGQEDQQQQQQQQQQQQQQQQQAPAEQTQGEPTK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : **: ** **********:**** ** **. . **:************************::*******.* .*.::::*: ** :*.** *. ***.**:.****.*.:*********************::*. *:.*::.** ***:**:** .:********************** ****:**:*** *************************************:. . : : :: *: ::: ", "identical_positions": 177, "similar_positions": 50, "identity": "64.84%" }, { "cls_id": "homologset.agr.SGD:S000002508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50580-1", "uniprot_id": "PA2G4_MOUSE", "id": "P50580-1", "name": "Proliferation-associated protein 2G4", "aln": "----MSGEDEQ---QEQTIAEDLVVTKYKMGGDIANRVLRSLVEAS---------SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQD------------------YILKEGDLVKIDLGVHVDGFIANVAHTFVIGVAQGTQ--------VTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWN----------------KVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN------------------------------------PTDQQKKDHEKAEFEVHEVYAVDVLVSSGE-----------------GKAKDAG---QRTTIYKRDPSKQYGLKMKTSRAFFSEVERR----------FDAMPFTLRAFE-------DEKKARMGVVECAK------------------------------------------HELLQP------------FNVLYEKEGEFVAQFKFTVLLMPNGP--------MRITSG--PFEPDLYKS--EMEVQDAELKALLQSSASRKTQKK----KKKKASKTVENATSGETLEENGAGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYD3-1", "uniprot_id": "PA2G4_RAT", "id": "Q6AYD3-1", "name": "Proliferation-associated protein 2G4", "aln": "----MSGEDEQ---QEQTIAEDLVVTKYKMGGDIANRVLRSLVEAS---------SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQD------------------YILKEGDLVKIDLGVHVDGFIANVAHTFVIGVAQGSQ--------VTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWN----------------KVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN------------------------------------PTDQQKKDHEKAEFEVHEVYAVDVLVSSGE-----------------GKAKDAG---QRTTIYKRDPSKQYGLKMKTSRAFFSEVERR----------FDAMPFTLRAFE-------DEKKARMGVVECAK------------------------------------------HELLQP------------FNVLYEKEGEFVAQFKFTVLLMPNGP--------MRITSG--PFEPDLYKS--EMEVQDAELKALLQSSASRKTQKK----KKKKASKTAENATSGETLEENGAGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQ80-1", "uniprot_id": "PA2G4_HUMAN", "id": "Q9UQ80-1", "name": "Proliferation-associated protein 2G4", "aln": "----MSGEDEQ---QEQTIAEDLVVTKYKMGGDIANRVLRSLVEAS---------SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQD------------------YILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQ--------VTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWN----------------KVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN------------------------------------PTDQQKKDHEKAEFEVHEVYAVDVLVSSGE-----------------GKAKDAG---QRTTIYKRDPSKQYGLKMKTSRAFFSEVERR----------FDAMPFTLRAFE-------DEKKARMGVVECAK------------------------------------------HELLQP------------FNVLYEKEGEFVAQFKFTVLLMPNGP--------MRITSG--PFEPDLYKS--EMEVQDAELKALLQSSASRKTQKK----KKKKASKTAENATSGETLEENEAGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03862-1", "uniprot_id": "ARX1_YEAST", "id": "Q03862-1", "name": "Probable metalloprotease ARX1", "aln": "MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYYKN-KVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGVSAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLAKDKRFGLLLKETQPMKQKSVETSNGGVEETMKM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ** * :::.* :: *:.**: .*:**: .*: :.. . ::* .** *::*: . : :*: * ::***:**:*.::: :.* .* : *: ****** ****:**: ::*:**:*: .: :: : * ***.: ***:. *:.: *: . ::. : . .:*:*:** : * :::::.: . :: *: : *: . :. .: *** :*: ::* * **::.** *. * ** :: : **:**** :::::::: . :**. . * * *. *:*: * :: *** * :* *. . **: *::* .. :*:*.* . :*. :* *:: **: ::.::* :: * :: *:.:. * . **. :**. ", "identical_positions": 114, "similar_positions": 155, "identity": "19.16%" }, { "cls_id": "homologset.agr.SGD:S000002512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8WCG0-1", "uniprot_id": "SERC4_RAT", "id": "A8WCG0-1", "name": "Serine incorporator 4", "aln": "--------------------------------------------------------------------------------------------------------------MGAKDITGRSTTQGFAQQHGGVSDVVVKTPFYQVSCCGPVSWTSGCHS----LTESTCSRLFYILLHMGASAICCLLLSKTVVERVWGKAHGIQMPSVLCA------HLFGN-SDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTSPRAQLHNSFWSLKLLFLLGLCTAAFCIPD-EHLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQ----DCSWFLGVLLATLGFYSMAGVGAVLLFHHYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRLRQPNSGLLQASIISCYIMYLTFSALSSRPP-ETIIFQ-GQNHTLCLP--------GQNKMEPQIPDASVAVFSASIMYACVLFACNEASY----LAQLFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQGS-RARPADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFS--YEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAHHSESPPP--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XK03-1", "uniprot_id": "SERC4_MOUSE", "id": "Q5XK03-1", "name": "Serine incorporator 4", "aln": "-------------------------------------------------------------------------------------------------------------MMGAKVVTGRSTTQGLAQQHGGVSN-VVETPFNQASCCGPVSWTSGCHS----LTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQMPSVLCA------HLFGS-SDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPRAQLHNSFWSLKLLFLLGLCVVAFCIPD-EDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQ----DCSWLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRRKQPNSGLLQASIISCYIMYLTFSALSSRPP-ETITFQ-GQNHTLCLP--------GRNKMEPQIPDTSVAVFSAGIMYACVLFACNEASY----LAELFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQRS-RARSADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFS--YEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAPHSESPPP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NH21-1", "uniprot_id": "SERC4_HUMAN", "id": "A6NH21-1", "name": "Serine incorporator 4", "aln": "-------------------------------------------------------------------------------------------------------------MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCSRLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCA------HLFGL-SDCPVLSGSGAVYRVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPD-EHLFPAWHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQ----DCSWFLAVLLATLGFYSMAGVGAVLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMYLTFSALSSRPP-ERVILQ-GQNHTLCLP--------GLSKMEPQTPDISLAMLSASIMYACVLFACNEASY----LAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWFS--YEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BHJ6-1", "uniprot_id": "SERC5_MOUSE", "id": "Q8BHJ6-1", "name": "Serine incorporator 5", "aln": "--------------------------------------------------------------------------------------------------------------MSARCCAG-----------------------QLACCCGSAGCSLCCGC-CPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVK---DHIPFFEEFCK------KTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVR----NKLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPE-KKVLDEHGKNVTICAP--------DFG-QDLHRDENMVTWLGTLLLIVCISYSCLTSTT----RSSSD-ALQS-RYGAPELEVARCCFCFGPDGEDTE------EQQNVKKGPRVIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFH--YENATIKT-FFSG-WSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63175-1", "uniprot_id": "SERC5_RAT", "id": "Q63175-1", "name": "Serine incorporator 5", "aln": "--------------------------------------------------------------------------------------------------------------MSARCCAG-----------------------QLACCCGSAGCALCCGC-CPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMT---EHIPFFEDFCK------GIKAG-DTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVR----NKLWYASLSLA-LIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPE-KVVKDEHGKNVTICVP--------DFG-QDFRRDESMVTWLGTLLLVVCISYSCLTSTT----RSSSD-ALQR-RYGAPELEVARCCFCFGPDGEDTE------EQQNVKEGPRVIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFH--YENATIET-FFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VE9-1", "uniprot_id": "SERC5_HUMAN", "id": "Q86VE9-1", "name": "Serine incorporator 5", "aln": "--------------------------------------------------------------------------------------------------------------MSAQCCAG-----------------------QLACCCGSAGCSLCCDC-CPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMK---EHIPFFEDMCK------GIKAG-DTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEFAHKWNKNWTAGTAS----NKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPA-EVVLDEHGKNVTICVP--------DFG-QDLYRDENLVTILGTSLLIGCILYSCLTSTT----RSSSD-ALQG-RYAAPELEIARCCFCFSPGGEDTE------EQQPGKEGPRVIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWFN--HVRSAFHL-LP-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803X0-1", "uniprot_id": "SERC5_DANRE", "id": "Q803X0-1", "name": "Serine incorporator 5", "aln": "--------------------------------------------------------------------------------------------------------------MCTPCCVS-----------------------QLACCCGSAACSLCCGC-CPKIKQSTSTRFMYALFFMLVTVTCVIMMSPTVEMAMR---EHIPFYSQMCQ------QLNAG-ENCSTLVGYSAVYKVCFGMACFFFFFAVFTIRVQNSTGCRAAVHNGFWFFKFVALLACCAGGFFLPNQDQFLEVWRYVGAAGGFLFIIIQLMLLVQFAHRWNQNWSSGATY----NKLWYAALALVTLVLFSVAVGGMVFMFMYYTHPEACFLNKIFLGVNGGLCFIVSLLAISPCIQTFQPTSGLLQPAVITLYVMYLTFSALASKPI-EMVEDEIKGNITVCVF--------PFK-SGLKSDTNIVTGVGTAILFCCILYSCLISTT----KRSSA-ALQVYRNDMPENERARCCFCWVDDTEDYD------DEKTS-GGQNVKYDERDGTVYSYCFFHFVFFLGSLYVMMTVTNWFH--YDNAKIER-LLEGSWSVFWIKMASSWVCLFFYMWTLVVPMLFPQRFQA----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QZI8-1", "uniprot_id": "SERC1_MOUSE", "id": "Q9QZI8-1", "name": "Serine incorporator 1", "aln": "--------------------------------------------------------------------------------------------------------------MGSVLGLCSVAS-------------------WIPCLCGSAPCLLCRCC--PSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCE--------------NEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIPE-GTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEG--NSRCWYAALLSATALNYLLSLVAVVLFFVYYTHPASCAENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPE-TNCNPSLLSIIG---------FNTTRPIPK---DGQSVQWWHPQGIIGLVLFLLCVFYS----SIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLD---------DGDGIHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYR----YEPS--REMKSQWTAVWVKISSSWIGLVLYVWTLVAPLVLTNRDFD----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNK0-1", "uniprot_id": "SERC1_RAT", "id": "Q7TNK0-1", "name": "Serine incorporator 1", "aln": "--------------------------------------------------------------------------------------------------------------MGSVLGLCSVAS-------------------WIPCLCGSAPCLLCRCC--PSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCE--------------NEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIPE-GTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEG--NSRCWYAALLSATALNYLLSLVAIILFFVYYTHPASCSENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITIYTMYLTWSAMTNEPE-TNCNPSLLSIIG---------FNTTRPVPK---DGQSVQWWHPQGIIGLVLFLLCVFYS----SIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLD---------DGEGVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYR----YEPS--REMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRX5-1", "uniprot_id": "SERC1_HUMAN", "id": "Q9NRX5-1", "name": "Serine incorporator 1", "aln": "--------------------------------------------------------------------------------------------------------------MGSVLGLCSMAS-------------------WIPCLCGSAPCLLCRCC--PSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCE--------------NEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPE-GTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEG--NSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPE-TNCNPSLLSIIG---------YNTTSTVPK---EGQSVQWWHAQGIIGLILFLLCVFYS----SIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLE---------DGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYR----YEPS--REMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZI9-1", "uniprot_id": "SERC3_MOUSE", "id": "Q9QZI9-1", "name": "Serine incorporator 3", "aln": "--------------------------------------------------------------------------------------------------------------MGAVLGVFSLAS-------------------WVPCLCSGASCLLCSCC--PISKNSTVTRLIYAFILFLGTIVSCIMMTEGIQTQLKKIPGFCEGGFQIKM------VDTKAEKDCDVLVGFKAVYRINFAVAIFFFAFFLLMLKVKTSKDPRAAVHNGFWFFKIAAIIGIMIGSFYIPG-GSFTEVWFVAGMLGASFFIIIQLVLLVDMAHSWNELWVNRMEEG--NPRLWYAALLSFTSLFYILSIVFAALLYVFYTKPDDCTENKVFISLNLIFCVAVSIVSILPKVQEHQPRSGLLQSSIITLYTLYLTWSAMTNEPE-RSCNPSLMSIITHLTSPTVSPANSTTLAPAYAPPSQSGHFMNLDDIWGLIIFVFCLIYS----SFRTSSNSQVNKLTLSGSDSVILGDTTN-GANDEE---------DGQ-PRRAVDNEKEGVQYSYSFFHLMLCCASLYIMMTITSWYS----PDAKF-QKVSSKWLAVWFKMGSSWLCLLLYLWTLVAPLVLTGRDFS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13530-1", "uniprot_id": "SERC3_HUMAN", "id": "Q13530-1", "name": "Serine incorporator 3", "aln": "--------------------------------------------------------------------------------------------------------------MGAVLGVFSLAS-------------------WVPCLCSGASCLLCSCC--PNSKNSTVTRLIYAFILLLSTVVSYIMQRKEMETYLKKIPGFCEGGFKIHE------ADINADKDCDVLVGYKAVYRISFAMAIFFFVFSLLMFKVKTSKDLRAAVHNGFWFFKIAALIGIMVGSFYIPG-GYFSSVWFVVGMIGAALFILIQLVLLVDFAHSWNESWVNRMEEG--NPRLWYAALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPD-RSCNPNLMSFITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYS----SIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEE---------DGQ-PRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYS----PDAKF-QSMTSKWPAVWVKISSSWVCLLLYVWTLVAPLVLTSRDFS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K0E7-1", "uniprot_id": "SERC2_MOUSE", "id": "Q8K0E7-1", "name": "Serine incorporator 2", "aln": "--------------------------------------------------------------------------------------------------------------MGACLGACSLLS-------------------CASCLCGSAPCILCGCC--PSTRNSTVSRLLFTSFLFLGVLVSIIMLSPGVESQLYKLPWVCEDRTQQP-------LVLQGPLDCGSLLGFRAVYRMCFATAAFFFFFMLLMICVRSSRDPRAAIQNGFWFFKFLILVGITVGAFYIPD-GSFPKIWFYFGVVGSFLFILIQLILFVDFAHSWNQRWLCKAEEC--DSPAWYAGLFFFTFLFYLLSIAAVALMFVYYTESGACHEGKVFISLNLTFCVCVSIIAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSNVPD-QKCNPHLP---TKNG---------TGQVDL---EDYSTVWWDAPSIVGLVIFILCTFFI----SLRSSDHRQVNSLMQTEECP---AEMVQQQQVAVS---------DGR----AYDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYS----PGE-T-RKMISTWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4FZV1-1", "uniprot_id": "Q4FZV1_RAT", "id": "Q4FZV1-1", "name": "", "aln": "MALVKFKSRFISKSLLWFSIQSELRVGLGCAPVVAGLFPISASLGKVWRQHLSQVSPTRSRALPESDERLRQVGRGRGGDGLGVGPVKAPRVPPDPGSEAGAPRPAPRTAMGACLGACSLLS-------------------CASCLCGSAPCILCSCC--PSTRNSTVSRLLFTGFLFLGVLVSIIMLSPGVESQLYKLPWVCEDRAQQP-------VVLQGPLDCGSLLGFRAVYRMCFATAAFFFLFMMLMICVRSSRDPRAAIQNGFWFFKFLILVGITVGAFYIPD-GSFPKIWFYFGVVGSFLFILIQLILFIDFAHSWNQRWLCKAEEC--DSPVWYAGLFFFTFLFYLLSIAAVALMFVYYTESGACHEGKVFIGLNLTFCVCVSIIAVLPKVQSAQPNSGLLQASVVTLYTMFVTWSALSNVPD-QKCNPHLP---TKNG---------TGQVNL---EDYSTVWWDAPSIVGLVIFILCTFFI----SLRSSDHRQVNSLMQTEECP---AEMVQQQQVAVG---------DGR----TYDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYS----PGE-T-RKMISTWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SA4-1", "uniprot_id": "SERC2_HUMAN", "id": "Q96SA4-1", "name": "Serine incorporator 2", "aln": "--------------------------------------------------------------------------------------------------------------MGACLGACSLLS-------------------CASCLCGSAPCILCSCC--PASRNSTVSRLIFTFFLFLGVLVSIIMLSPGVESQLYKLPWVCEEGAGIP-------TVLQGHIDCGSLLGYRAVYRMCFATAAFFFFFTLLMLCVSSSRDPRAAIQNGFWFFKFLILVGLTVGAFYIPD-GSFTNIWFYFGVVGSFLFILIQLVLLIDFAHSWNQRWLGKAEEC--DSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTEPSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPE-QKCNPHLP---TQLGN-------ETVVAGP---EGYETQWWDAPSIVGLIIFLLCTLFI----SLRSSDHRQVNSLMQTEECPPMLDATQQQQQVAAC---------EGR----AFDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYK----PGE-T-RKMISTWTAVWVKICASWAGLLLYLWTLVAPLLLRNRDFS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AIB7-1", "uniprot_id": "A0A8M3AIB7_DANRE", "id": "A0A8M3AIB7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGACMALCSLAS-------------------CASCLCGSAPCLLCGCC--PSTNNSTITRLIFSFFLLLGTLVSVIMILPGMETQLRKIPGFCQGGTTIP-------GIEN-HVNCDVIVGYKSVYRMCFAMACFFFLFFAIMIRVKSSKDPRAAVQNGFWFFKFLILVGITVGAFFIPD-GTFHDVWFYFGIVGSFAFILIQLILLIDFAHSWNEVWVRNAEEG--NSKCWFSGLLFFTILYYALAFAAIVLFYLYYTKPDNCTEHKFFISFNLILCVIVSVVSILPKVQDASPQSGLLQSSIITLYTMYVTWSAMTNNPN-RECNPSLLGLVSNIST-------TEAVPTS---SPGTVQWWDAQGIVGLVIFLFCTFYA----SIRSSSNAQVNRLMQTEEGK---GGVGGEEVGEDG---------LRR----VVDNEEDGVTYNYSFFHFHLLLASLYIMMTLTNWYK----PDTTT-QAMQSTMPAVWVKICSSWLGLGLYLWTLVAPVIFSNRDFS----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFR2-1", "uniprot_id": "M9PFR2_DROME", "id": "M9PFR2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGAALGICSAAQ-------------------CAMCCGGTAASMCCSAC--PSCTNASSSRFMYAFILLVGTVLGAIALSPGLQDTLKKMPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSRDPRSHIQNNFWPLKFLICFGAAIGAIFIPD-GSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAENWIESAE----NSRGYYYALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISVISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPE-KECNPGMFGMMEGFGN------ATTTAAPP---THTTRVTFDTTNIIGLVVWLLCILYN----CISS--AVEVSKISHDNSEKR--EALSDTEAGTDG---------SGK---PSTDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWYNNFLFPQTSFGNRAVQRQRGFHVGQDRLQLAGCLHLWLEPCSAHCSYQSRL----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12116-1", "uniprot_id": "TMS1_YEAST", "id": "Q12116-1", "name": "Membrane protein TMS1", "aln": "--------------------------------------------------------------------------------------------------------------MGAVISLPVSMAG-----------------SFVASCFGGCCSNLVTKTASSLGSSSLGTRLLYAVWLLLNSLISWVSYSANKSILWP-----------------------GKTCTGTGECGFFTVHRLNFALGCLHLILALVLTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPN-DFYIFFSKWVSVPSGAIFILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFCH-QQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSS---------PTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVT---QDDVGDFIPVGRTYFYSWVKIVSAWICYALYGWTVVAPAIMPDRFDYENYY------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : :*::: : * :*::: . . :. . : .. . *: ::*.:* :*: .: :* . .. ** : *::: :*: : : : : : .: : * : : .: : . :: * :: * *** *..::: * ::* **::. * . : * : **. : .: : : :* ", "identical_positions": 28, "similar_positions": 80, "identity": "4.27%" }, { "cls_id": "homologset.agr.SGD:S000002514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLL4-1", "uniprot_id": "TM9S4_RAT", "id": "Q4KLL4-1", "name": "Transmembrane 9 superfamily member 4", "aln": "--------------------MAAAMIWWPRFLLLLCLTC---KGSTFYVPGVAPINFHQNDP--------VEIKAVKLTSSRTQLPYEYY--SLPFCQPNKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCGQSNKP-VILTVEQSRLVAERITEEYYVHLIADNLPVA-TRLELYSSNRDSDD-------KKKEKDVQFEHGYRLGFTDVNK-------------------------IYLHNHLSFILYYHREDTEEDQ---EHTYRVVRFEVIPQSIRLEDLKIDEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESD-IKWASRWDTYLT-MSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPY-DNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH24-1", "uniprot_id": "TM9S4_MOUSE", "id": "Q8BH24-1", "name": "Transmembrane 9 superfamily member 4", "aln": "--------------------MAAAMIWWPRFLLLLCLTC---KGSTFYVPGVAPINFHQNDP--------VEIKAVKLTSSRTQLPYEYY--SLPFCQPIKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCNQSNKP-ITLTVEQSRLVAERITEEYYVHLIADNLPVA-TRLELYSSNRDSDD-------KKKEKDVQFEHGYRLGFTDVNK-------------------------IYLHNHLSFILYYHREDMEEDQ---EHTYRVVRFEVIPQSIRLEDLKTGEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESD-IKWASRWDTYLT-MSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPY-DNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92544-1", "uniprot_id": "TM9S4_HUMAN", "id": "Q92544-1", "name": "Transmembrane 9 superfamily member 4", "aln": "--------------------MATAMDWLPWSLLLFSLMC---ETSAFYVPGVAPINFHQNDP--------VEIKAVKLTSSRTQLPYEYY--SLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSNKP-VTLTVEQSRLVAERITEDYYVHLIADNLPVA-TRLELYS-NRDSDD-------KKKEKDVQFEHGYRLGFTDVNK-------------------------IYLHNHLSFILYYHREDMEEDQ---EHTYRVVRFEVIPQSIRLEDLKADEKSSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESD-IKWASRWDTYLT-MSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPY-DNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58021-1", "uniprot_id": "TM9S2_MOUSE", "id": "P58021-1", "name": "Transmembrane 9 superfamily member 2", "aln": "-----------MSSRPPASPPAQGSRLLLLSLLLLGTVPGPRPGSAFYLPGLAPVNFCAEEK-SNECKADIELFVNRLDSVESVLPYEYT--AFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKKETCKLVCTKTYNTEKAEDKQKLDFLKKSMLLNYQHHWIVDNMPVT-WCYEVEDSQKFCNPGFPIGCYITDKGHAKDACVISSEFHERDT-------------------------FYIFNHVDIKIYYHVVETGSMG------ARLVAAKLEPKSFKHTHI---DKPDCSG-PAMDISN---KASGEIKIAYTYSISFEEEKNIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKLVHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALWFCISVPLTFIGAYFGFKKNAI-EHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAIHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG5-1", "uniprot_id": "TM9S2_RAT", "id": "Q66HG5-1", "name": "Transmembrane 9 superfamily member 2", "aln": "-----------MSSRPPASLPARGPRLLLLSLLLLGTVPGPRPGSAFYLPGLAPVNFCTEEKKSNECKAEIELFVNRLDSVESVLPYEYT--AFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKEETCKLVCTKTYHTEKAEDKQKLDFLKKSMLLNYQHHWIVDNMPVT-WCYEVEDNQKFCNPGFPIGCYITDKGHAKDACVISSEFHERDT-------------------------FYIFNHVDIKIQYHVVETGSMG------ARLVAAKLEPKSFRHTHI---DKPDCSG-PAMDISN---KASGEIKIAYTYSISFEEEKNIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKLVHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALWFCISVPLTFIGAYFGFKKNAI-EHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLVYAIHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99805-1", "uniprot_id": "TM9S2_HUMAN", "id": "Q99805-1", "name": "Transmembrane 9 superfamily member 2", "aln": "-----------MSARLPVLSPPRWPRLLLLSLLLLGAVPGPRRSGAFYLPGLAPVNFCDEEKKSDECKAEIELFVNRLDSVESVLPYEYT--AFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKKETCKLVCTKTYHTEKAEDKQKLEFLKKSMLLNYQHHWIVDNMPVT-WCYDVEDGQRFCNPGFPIGCYITDKGHAKDACVISSDFHERDT-------------------------FYIFNHVDIKIYYHVVETGSMG------ARLVAAKLEPKSFKHTHI---DKPDCSG-PPMDISN---KASGEIKIAYTYSVSFEEDDKIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKLVHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALWFCISVPLTFIGAYFGFKKNAI-EHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAVHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIK1-1", "uniprot_id": "Q9VIK1_DROME", "id": "Q9VIK1-1", "name": "Transmembrane 9 superfamily member", "aln": "-------------------MILLSGLLPLLGVVLLHLAT---PTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYEYH--HFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVT-WCYPLENGKQYCGIGFPMGCLVRSDG---EGCPINSIYNQPMH-------------------------YYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDK---ENPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRAL-EHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2AFI6-1", "uniprot_id": "A2AFI6_MOUSE", "id": "A2AFI6-1", "name": "Transmembrane 9 superfamily member", "aln": "MVVPEAGFKMGLSGRRVETKLCPGLHGLKWWLLLCFLAT---TCDAFFFPGLVPVTYCEEGHPNSYCKSSIQVYADKLYSVDSVMFYDYD--SFDFCQDSLKRTPSETLGQILFGEQVTSCPYKFSFNKDETCRKVCVKSYAPDNEDDMNKLAFLKKGIKQDYRHHWIVDNTGII-WCYDTENEEHHCMSGFPIGCFNAPSDQVKGSCLINPEFNKNNS-------------------------LYLFNHLDITITYHIESDTTVK-----VAKLISSRVDPKSYKHLDE---DHLTCNE-PPMEIPE---EDTENLNVIYTYSVKFEESKATEWSSEGDYDLDSTAETSLQWIRLVNSFFVVLFLCGLVVILLLRSIWRDIAKFNRIKISVYDRRLFGWRLIHGNLFRLPEHGMLLSILLGQGTQVFIMTFLSLFLAGLGFLTPADQNVLVNYGVVLWLALEIPAGYMSAKMYKTFKGINWKMHFLLTTVLFPGIVFADIFIMNLILWMDGSPAAISFCTLASLFALYFGVSTPLTFLGVYFG-KREKF-EFPVYAPKHEHGSPQRTFFPKSTITIILGSLLPFGCIFLQLSYILNRIWSPHMYYLFAFLLLLFLIFMISCSEVTVLLCYFRLCAEDRGWWWRAFLTSSFTSAYIFIYVIHYFFTKLQVTSIGSTFMYFGYAFILVLAFFLFTGTIGFFSCFFFVTTIYGVIKED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04562-1", "uniprot_id": "TMN2_YEAST", "id": "Q04562-1", "name": "Transmembrane 9 superfamily member 2", "aln": "------------------MKRGVWLLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTPSIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEHVEKQPESLGSVIFGDRIYNSPFQLNMLEEKECVALCKSTIPG------KDAKFINTLIKSGFFQNWLVDGLPAARKAYDSRTKTNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDARLPKNVKPNLVKTVELPYFVNHFDIEVEFHDRGNDNYR--------VVGVIVNPVSIERSSP-----GACSTTGKPLILD----EDKDNEVYFTYSVKFVASD-TVWATRWDKYLH-IYDPQIQWFSLINFSVIVILLSSVVMHSLLRALKSDLARYNELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSIFFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILLPGAIFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWDEHPTKTNQIARQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFGFLLFSFLLLTLTTSLVTILITYYSLCLENWLWQWRSFIIGG-LGCSIYTFIHSILFTKFKLGGVITVVLYLGYSLIISALCCVVTGAIGFFSSMFFIRKIYSAIKVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. . *: . *:* : ** *.**.:: *::: *::. : ..: * * .: . .: : : : :.*. . . * **..: : :* :: : * * . * : :: :***: : .. *::. * * . ::*: ::* .:*::*..:: ::*:: *:*.:*. . . **:* **::** * *:** ::*.* *:: * : : .* :*:::* .:. * . .*: : ..: : .*: : * ** : *. : ** :* .::* .: *...:. :: :: ::* :* ** : * .. :: : *. : : : * : : . ::..::.**.: ::* :* . :* :::*:*.**:: *::: :: * :::: *: ** *: * ** *: .. . . : :..*:.: . .:*:**: :: :.**:***::. *: .**..:* :", "identical_positions": 103, "similar_positions": 207, "identity": "14.39%" }, { "cls_id": "homologset.agr.SGD:S000002515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9W9-1", "uniprot_id": "F1M9W9_RAT", "id": "F1M9W9-1", "name": "", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHIIKNLKIAVSNIVTQPPQPGAIGKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPASDHEFLNHYLACMLVASSAEAEPMEQFSKLSQEQHRIQHNSDYSYPKWFIP-NTLKYYVLLHDVTSGDEQRAESIYEEMKQKYGTQGCYLLKINSRAPNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTMTSSKNSDSNLLSLDGLDNEVK-DGLPDN-------CRVHPLQIDQCGDTPHNTDGSDHAKSASSVHETKKA---STGLIRGACLTLTDHDRIRQFIQEFTFRGLLPHVEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSISELKSTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAEILKSQSKYAEAAALLIRLTSEQNTWKGLDSDLRSALLLEQAAHCFINMKNPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVNQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDAESSQQWRELEEHVVAVANKGVIPSSFYPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVPLLLSDLSLLWKFQPKDTSGKDTE--KERVTGEP------EMIGTEVISEFLINSEESKVARLKLFPHHIGELHILGVVYNLGTIQGSVTVDGIGALPGCHTGKHSLGMSVRGRQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIVTEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSQCPLTALKVVSKRPEFFTFGGNTAALTPLSPSTSENCSAYKTVVTASPSLGTAFVSTASSVDFGTGTGQQLEAIPVPLPDSVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKKRHRILRHTAVICTSRSLNVRATVCRSNSLEDEEGRGGNMLVFVDVENTNTSEAGVKEFHMVQVSSSSKHWQLHRSVNISENRDAKLASREKGKFCFKAVRCKQKEGDKQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELRRTQDQLPAYPEKN--ASEGAVRLIEKCSEVDLSIVVLWKAYVVEDNKQLILEGQHHVVVRTVGKEACSHSQKQEPPEMELLKFFRPENTTVSARPSVEQLSNLIKTSLHYPESFHHPFHQKSLCLVPVTLLLSNCSKAEVDVIVDLRHKTTSPEALETHGSFTWLGQTQYKLQLKSQETHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIINNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A286YCX6-1", "uniprot_id": "A0A286YCX6_MOUSE", "id": "A0A286YCX6-1", "name": "", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFSELLKPFSRLTSEVHMRDPNNQLHIIKNLKIAVSNIVTQPPQPGAIGKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPASDHEFLNHYLACMLVASSGEAEPMEQFSKLSQEQHRIQHNNDYSYPKWFIP-NTLKYYVLLHDVTSGDEQRAESIYEEMKQKYGTQGCYLLKINSRAPNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTMTSSKNSDSNLLSLDGLDNEVKVDGLPNN-------FRIHPLQIDQCGDPPNNTDGS-ESKSASSVHETKKA---STAVIRGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINELKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAEILKSQSKYSEAAALLIRLTSE-------DSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVNQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHISLDQEYDSESSQQWRELEEHVVAVANKGVIPSSFYPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVPLLLSDLSLLWKFQPKDASGKDIEKVKERVTGEP------EMIGTEVISEFLINSEESKVARLKLFPHHIGELHILGVVYNLGTIQGSGTVDGIGALPGCHTGKHSLSMSVRGRQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIVTEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAALTPLSPSTSENCSAYKTVVTASPSLGTALVSTASSMDFGTGTGQQLEAIPVPLPDSVLLPGASIQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKKRHRILRHTAVICTSRSLNVRATVCRSNSLEDEEGRGGNMLVFVDVENTNTSEAGVKEFHMVQVSSSSKHWQLHKSVNISENKDAKLASREKGKFCFKAVRCKQKEGGIQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELKKTQDQLSAYPEKHREATEGAVRLVEKCSEVDLSIVILWKAYVVEDNKQLILEGQHHVVVRTVGKEAFSHSQKEEPPEMELLKFFRPENTTVSTRPSVEQLSNLIKTSLHYPESFHHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALETHGSFTWLGQTQYKLQLKSQEMHSLQLKACFVHTGVYNLGTPRVFAKLSDHVTVFETSQQNSMPALIIINNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L5-1", "uniprot_id": "TPPC8_HUMAN", "id": "Q9Y2L5-1", "name": "Trafficking protein particle complex subunit 8", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHVIKNLKIAVSNIVTQPPQPGAIRKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPALDHEFLNHYLACMLVASSSEAEPVEQFSKLSQEQHRIQHNSDYSYPKWFIP-NTLKYYVLLHDVSAGDEQRAESIYEEMKQKYGTQGCYLLKINSRTSNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTITSNKNSDNNLLSLDGLDNEVK-DGLPNN-------FRAHPLQLEQSSDPSNSIDGPDHLRSASSLHETKKG---NTGIIHGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINDLKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAELLKSQSKYSEAAALLIRLTSE-------DSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVSQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDSESSQQWRELEEQVVSVVNKGVIPSNFHPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVLLLLTDLSLLWKFHPKDFSGKDNEEVKQLVTSEP------EMIGAEVISEFLINGEESKVARLKLFPHHIGELHILGVVYNLGTIQGSMTVDGIGALPGCHTGKYSLSMSVRGKQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIITEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAVLTPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLPDTVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKIRHRILRHTAIICTSRSLNVRATVCRSNSLENEEGRGGNMLVFVDVENTNTSEAGVKEFHIVQVSSSSKHWKLQKSVNLSENKDTKLASREKGKFCFKAIRCEKEEAATQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELKKPQAHLPVHTEKQ--STEDAVRLIQKCSEVDLNIVILWKAYVVEDSKQLILEGQHHVILRTIGKEAFSYPQKQEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW22-1", "uniprot_id": "Q9VW22_DROME", "id": "Q9VW22-1", "name": "", "aln": "MLHLTGQSYNARDIIRNIFSPLIGVLSSPQADEICHRNNLSFVELLQPFAKLPNDAHFRDVSGTSVSVRGLRLNFCDVDWRPPQTILARKMLNESVTNAHNDK---TRLATIAGIDLELPTSEPWFEQWRETFLTVQFPADHEFTRHLLSCLLVLSSADPQIVETAHKLGQRVQQMQSITPQKLPKWFHPTEVLNSYVVLHEASQGDLSKAQQGFELLKSTFGDSKCFLVSINSMDS--QGAAEVPDHWATFIKRQPKSDP-NLPSTDLSAPKSPQEAVSVISMPAMQMSQLLEGVSAQDSDLAMLHPLSPMQESATEAINSKFSISSESIASQTINPNVWGNELEADAPHGGCLTSRDIDNLRHFVQDYAVRALIPYIEHLVAILAEGVTNKKGVSKSLLSATKRWFVTSKPGAG----ANNQNAVIYTNESAELQTRKLGDLYFMFGHYNLAFQSYHQAKRDFNADSAWQYYAGALEMAALSAFMLGTAQR-KTYDYMEDAIVCYLTVCKLQQFATRATLLSMECLKTARLYSEVAKQLIRMTNE-------ESDLRSALLLEQAAYCFLVTQPPMHRKYAFHIVLAGNRYSRAGQRKHAYRCYRQAYQVFQKREWSLAEDHIQYTVAKQAYMLKQLEEASRSFAHLLRPGSLQSAQQQTSFLKEYIQTQNELVKRSPELGLLPHALPQVVQSSVRVLTLVQSPSAVAPHVPATNIDINSNLTADEP-IWNKIEEMLVITAAN-NKPFVFKPSRYLYTKQQPALETPVAVQGEPIELAVTLSNSVQCRIALSEIDLLWKLTLDNDEVLSNACTYEESSDSANKIAVGAAIKTSCMASIKLAEQAEETLHFKLTPKLTGRLSILGVVCRVAAGADP-------------------AASLLGTLQFETQKIRPHNAKQSSQTVMDN---RLTIKLVPQLPAMNVSFTPVPNRLLAGEIVPVHVTLRNMGIAPIEEIYLGCDNPRCVSLLDQHSQMPLAMMSSLRNLSNDKLVKDKE------------------IRGQRVYRLLNRPGLAALDAQQVQTISLWVQAPHQAGPFTLRLLFYYSLPTVANSPIKYRLVRHIWQLQVESCLQADSTCVVSNAVTNELG--------LDVNVRNQHAVEGTEVYINSISLYSTEFKLNPDR-LHIMNSMGVSPGQAGAQCLKSS--------------------------------ICCNFQCRLLEKETQEEYKDIPS------------IKTLLHSRLSHLKILPAQHAQQVEQHMPPIHD--PHSFLTNEETVYFNTNISTEEFNASVADYVPHATLVLSWSALVAREEGQRLACGLHFIKLYKLFETGHCPAAPTASFLR--RRHSSDDTLDNRREFPLPEGALNN-------EDAWQPLADADEEDYWEPNENYVGQRCLLEDESFVMAVKA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46944-1", "uniprot_id": "TRS85_YEAST", "id": "P46944-1", "name": "Trafficking protein particle complex III-specific subunit 85", "aln": "-------------------------------------MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTSTP--------------------------------------------------LFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDS------------------------------------------------------------------------TDSIPKNKNLEVPNLSKKGSRSRSNSLFQRDSTQSQYI-----------------------------------------------------RFTRPLGDLIETRDAN--DMLFNYHSLEVFLDNYLKLVAANTDEMVPHNLLKKSIYHS-----------------------------------------------------------------------------------------------FFSLAISSTNNLSPYETFNHPILSLIALDISNGEVYEDARDLLVNFKNLN--------------------------------------------------------HNTENFPIFMNTNEMLPVFLLCYNDDSQ-----EEFEKCQALAKKLKKQLFVESILLALWKDSFIYDENSVIQLHQP----------VMSSLEEILFFLQAP--------------------------------------------------------------------TQTTLSLALINSIYDMLDYLVYDLMIPFMKR---------------------------KVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGNHQHNSLTRDS-----------------------QGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKYLAS---------------CIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRG-----------------------KGKESNSLDVTEPVRSYETRCMILASELFLSLSNTWTSTP------------------YAIQYLETILDECKLGPCSQIMVWERLSDCYN--------LRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRR----------------------------------------------------------------------------------KAAFFRLIAAKKWAEQKQWR------------------QVSWCLKDIESTYSEIKFLHGNGLILS--------------------KLKNQLNLKDVDSAPR-----------------------------------------------PSEKNLTRTSVSFIG---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . :: : :* .. . . : . . : * :: ::. : :. .. . . *:.*. :.: . :. . . : . . .::. . : . * : * : :.: .:.. :: : : : : :: :.:*: : ::. ** :. : * :.. * :. *:.:.. : :: *. : :. * : : :: : * .: : .:: :.: : : .* .:: : : ::: *.: : .*: : .. . : . . *: : .. : * . . .. * : . . * . :: . : ::. ... : ..: : . : .: : :: .* * : *.. : . . . . : ::: : . * : : : : . : *: . : . . . : . . . : :: : :: . . . .:. :* .: : :. .* ..* . . . :: ", "identical_positions": 31, "similar_positions": 222, "identity": "2.11%" }, { "cls_id": "homologset.agr.SGD:S000002516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJL3-1", "uniprot_id": "FGGY_MOUSE", "id": "A2AJL3-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "------------------------------MMSGRDQEPSRYYVGIDVGTGSVRAALVDQRGLLLAFAEQPIKKWEPQFNHHEQSSEDIWAACCLVTKEVVQ--GIDAHRIRGLGFDATCSLVVLDKE-FHPLPVNHEGDS-SRNVIMWLDHRAVSQVHRINETKHRVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYS--AEKG----WDDSFWKMIGLEDLIDDNYSKIG------NLVLLPGAALGIGLTPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQP--------VTSRLAVICGTSSCHMGISKDPVFVPGVWGPYYSAMVPGFWLNEGGQSVTGKLIDHMVQGHPAFPELQAKATARCQSIYAYLNSHLDLIK---KAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSQDLDDLAILYLATVQAIAFGTRFIIETMEAAGHS-LSTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVE-SVLVGAAILGACASGDFTSVQE-----------------------------------------------------------------------------------------------------AMARMSKVGKVVFPE---HADKKYYDKKYQVFLRMVEHQKEYSAIMNGS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LSP9-1", "uniprot_id": "F1LSP9_RAT", "id": "F1LSP9-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "MDIQTHVLTHMQQVLPLAEPLPSPVHGRGTMMSGGDQEPDHYYVGIDVGTGSVRAALVDQRGVLLAFAEQPIKKWEPQFNHHEQSSEDIWAACCRVTKEIVQ--GIDAHRIRGLGFDATCSLVVLDKE-FHPLPVNREGDS-SRNIIMWLDHRAVSQVHRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYS--AEKG----WDDSFWKMIGLEDLIGDNYNKIG------NLVLPPGASLGSGLIPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQP--------VTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQSHPAFPELQAKATARCQSIYAYLNSHLDLIK---KAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSRDLDDLAVLYLATIQAIAFGTRFIIETMEAAGHS-LSTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVE-SVLVGAAILGACASGDFASVQE-----------------------------------------------------------------------------------------------------AMARMSKVGKVVFPE---RADKKYYDKKYQVFLRMVEHQKEYSAIMNGS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C11-1", "uniprot_id": "FGGY_HUMAN", "id": "Q96C11-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "-------------------------------MSGGEQKPERYYVGVDVGTGSVRAALVDQSGVLLAFADQPIKNWEPQFNHHEQSSEDIWAACCVVTKKVVQ--GIDLNQIRGLGFDATCSLVVLDKQ-FHPLPVNQEGDS-HRNVIMWLDHRAVSQVNRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYS--AEKG----WDDSFWKMIGLEDFVADNYSKIG------NQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGLGVIGADVRGHGLICEGQP--------VTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIK---KAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLKLSQDLDDLAILYLATVQAIALGTRFIIEAMEAAGHS-ISTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVE-SVLVGAAVLGACASGDFASVQE-----------------------------------------------------------------------------------------------------AMAKMSKVGKVVFPR---LQDKKYYDKKYQVFLKLVEHQKEYLAIMNDD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUW9-1", "uniprot_id": "FGGY_DANRE", "id": "Q6NUW9-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "-------------------------------MG------SWYYVGVDVGSASVRAALVSPDGQLRRTAEEPIAVHEPCVDHYEQSSTEIWSKCCQTVKRVTE--GVDAACVRGIGFDGTCSLVVLDQQ-FRPLAVNLAGVC-DRNVVMWMDHRAAAQASRITACRHTLLQRVGGVMSPEIQPPKLLWLKENLPDSCWTRAAHFFDLPDFLSWKATGSLSRSLCTLVCKWTYS--ASEG----WDDTFWSAIGLEDLIEDSYARIG------SQVCCPGAAVGRGLTAAAAADLGLNEGTAVGASLIDAHAGGIGVLGADVSGLHLPCEHQP--------LTARMALICGTSSCHMAVSREPLLVPGVWGPYLSAMLPGLWLNEGGQSATGKLLDHVVKGHAAFRQLEEQAEHSGRHIYTQLNLHLQQMST--DATHLEQLTTHLHIWPDFHGNRSPLADQTARGTVVGLSLSQTLDDLALLYLATLQALALGSRHIIAAMTEAGHD-ITTLFLCGGLSKNTLFVQTHANTTGLPVVLPAERE-AVLLGAAVIGACASSDCTSIPE-----------------------------------------------------------------------------------------------------AMRKMSRVGRVVRPN---PELQSFYRRKYSVFLRLYQHQKECVSLMED-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZJ8-1", "uniprot_id": "Q9VZJ8_DROME", "id": "Q9VZJ8-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "-------------------------------MS-----SGPFFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIG--GVDKSKVKGIGFDATCSLVVLGPQ-GSPLTVSKSGEA-EQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGN-IWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYD--AANGS---WNKEFLKQADLEELTQNNFEKLG------SDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSK---ESKGADD--------VQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGE-DKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQE-MVLVGAAALGAAASGHFDSLES-----------------------------------------------------------------------------------------------------ASKSMGGTGQLVKPN---AETLEFHNRKYKVFLQLLENQRQYRRIMQADTK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04585-1", "uniprot_id": "YDR09_YEAST", "id": "Q04585-1", "name": "D-ribulokinase YDR109C", "aln": "--MKSRKRQNNMQNETREPAVLSSQETSISRISPQDP-EAKFYVGVDVGTGSARACVIDQSGNMLSLAEKPIKREQLISNFITQSSREIWNAVCYCVRTVVEESGVDPERVRGIGFDATCSLVVVSATNFEEIAVGPDFTNNDQNIILWMDHRAMKETEEINSSGDKCLKYVGGQMSVEMEIPKIKWLKNNLEAGIFQ-DCKFFDLPDYLTFKATGKENRSFCSAVCKQGFLPVGVEGSDIGWSKEFLNSIGLSELTKNDFERLGGSLREKKNFLTAGECISP-LDKKAACQLGLTEHCVVSSGIIDAYAGWVGTVAAKPESAVKGLAETENYKKDFNGAIGRLAAVAGTSTCHILLSKNPIFVHGVWGPYRDVLARGFWAAEGGQSCTGVLLDHLITTHPAFTELSHMANLAGVSKFEYLNKILETLVEKRKVRSVISLAKHLFFYGDYHGNRSPIADPNMRACIIGQSMDNSIEDLAVMYLSACEFISQQTRQIIEVMLKSGHE-INAIFMSGGQCRNSLLMRLLADCTGLPIVIPRYVDAAVVFGSALLGAAASEDFDYTREKRTLKGQKSSQTKTERFNDSYSSIQKLSMEDRNSTNGFVSPHNLQLSTPSAPAKINNYSLPICTQQPLDKTSEESSKDASLTVGQESLGEGRYNGTSFLWKVMQELTGNARIVNPNEKTHPDRILLDTKYQIFLDMIETQRKYRRMVDKVEGSFSR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ::**:***:.*.**.:: * : * :.* : .. *** :** * .: : *:* ::*:***.******:. :.*. :*:::*:**** :. .*. . *: *** :* *:: **: ***.** :.*****:*:::*** **:*: *** : . :* *.. * . .*.:: :.: ::* . . .* :. * ** :*** .*.:.:***:** :* ... .::* :.***:**: :::.. :. ****** ..: * : ***** :* *:**:: * :: :*. : ** * : : *: .:..: * ******:** . :. : * : . :.**: **: : :: :* ** : *: : ::::.** .:*.* :: *: .:* ::. : *:.*:* :**.** . . . : .::* *. **.:** : : *:: ::: ", "identical_positions": 150, "similar_positions": 178, "identity": "20.8%" }, { "cls_id": "homologset.agr.SGD:S000002518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QZR5-1", "uniprot_id": "ALAT1_MOUSE", "id": "Q8QZR5-1", "name": "Alanine aminotransferase 1", "aln": "-----------------------------------------------------------------------------MASQRNDRIQASRNGLK---GKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPD--------FPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVAGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQA-RDRCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFEEGLFLMADEVYQDNVYAEGSQFHSFKKVLTEMG---PPYATQQELASFHSVSKGYMGECGFRGGYVEVVNMDAEVQKQMAKLMSVRLCPPVPGQALMGMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPQIQLPLKAVQRAQDLGLAPDMFFCLCLLEETGICVVPGSGFGQQEGTYHFRMTILPPMEKLRVLLEKLRHFHAKFTHEYS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25409-1", "uniprot_id": "ALAT1_RAT", "id": "P25409-1", "name": "Alanine aminotransferase 1", "aln": "-----------------------------------------------------------------------------MASRVNDQSQASRNGLK---GKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPD--------FPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVSGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQA-RDRCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFKEGLFLMADEVYQDNVYAEGSQFHSFKKVLMEMG---PPYSTQQELASFHSVSKGYMGECGFRGGYVEVVNMDAEVQKQMGKLMSVRLCPPVPGQALMDMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPQVQLPLKAVQRAQELGLAPDMFFCLCLLEETGICVVPGSGFGQQEGTYHFRMTILPPMEKLRLLLEKLSHFHAKFTHEYS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24298-1", "uniprot_id": "ALAT1_HUMAN", "id": "P24298-1", "name": "Alanine aminotransferase 1", "aln": "-----------------------------------------------------------------------------MASSTGDRSQAVRHGLR---AKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPN--------FPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQA-RDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMG---PPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYL5-1", "uniprot_id": "ALAT2_DANRE", "id": "Q6NYL5-1", "name": "Alanine aminotransferase 2-like", "aln": "---------------------------MLSKRSLRVLKWGRCEAAYAAAYPKVPDWVLNFSPLPSLSSPHRDFSAFPAAQSEHMQQKMSENGAIPRQGKVLTVDTMNANVKKVDYAVRGPIVQRAVQIEKELKEG-VKKPFDEVIKANIGDAHAMGQRPITFFRQVMALCTYPQLLDDNK--------FPEDAKNRARRILQSCGGNSIGAYTTSQGIDCVRQDVAKYIERRDGGIPSDPDNIYLTTGASDGIVTILKLLTAGEGLTRTGVMISIPQYPLYSASIAELGAVQINYYLNEEKCWSLDISELQRSLQAA-RKHCNPRVLCIINPGNPTGQVQSRQCIEDVIQFAAKENLFLMADEVYQDNVYAKGCEFHSFKKVLFEMG---PEYSKKVELASFHSTSKCYMGECGFRGGYMEVINMDADVKAQLTKLVSVRLCPPAPGQALMDLVVNPPQPGEPSHQTFMQERTAVLSALAEKAKLTEQILNTVPGISCNPVQGAMYSFPRITLPERAISEAKAKGQAPDMFYCMKLLEETGICLVPGSGFGQREGTYHFRMTILPPTDKLKLMLNKLKDFHQRFTQQYS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IKG8-1", "uniprot_id": "A0A0R4IKG8_DANRE", "id": "A0A0R4IKG8-1", "name": "alanine transaminase", "aln": "---------------------------------------------------------------------------------------MTENGCEYHER-VLTVDTMNPNIKRLEYAVRGPIVQRAVQIDKELKMG-IKKPFTEVIKANIGDCHAMGQKPITFFRQVLALCSYPDLLEDNK--------FPEDAKSRAQRILKACGGGSLGAYSTSQGIEMIRQDVARYIERRDGGIACDPDNIYLSTGASDAIVTMLKLMVSGEGASRTGVMISIPQYPLYSAALAELGAVQINYYLDEDNCWSLDINELRRALQEA-KKHCRPRALCIINPGNPTGQVQSRQCIEEVIRFAADENLFLMSDEVYQDNVYADGCKFHSFKKVLFEMG---PQYSSKVELASFHSTSKCYMGECGFRGGYMEVVNLDPEVKVQLTKLVSVRLCPPVPGQALLDVVVNPPQPDEPSYDTFIKERSDTLAALAEKASMTQDILNQVPGIKCNPVQGAMYTFPRIHLPPKAILKAKENGQSPDMFYCMKLLEETGICLVPGSGFGQRDGTYHFRMTILPLKDKLKVVLAKIKDFHQIFTEQYS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BGT5-1", "uniprot_id": "ALAT2_MOUSE", "id": "Q8BGT5-1", "name": "Alanine aminotransferase 2", "aln": "--------------------------------------------------MQRAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPERSPR---DRILTLESMNPQVKAVEYAVRGPIVLKAGEIEMELQRG-IKKPFTEVIRANIGDAHAMGQQPITFLRQVMALCTYPNLLNSPS--------FPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFITRRDG-VPADPDNIYLTTGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAVQVNYYLDEENCWALNVDELRRALRQA-KDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYQMG---HEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPEPGEESFEQFSREKEFVLGNLAKKAKLTEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVDKLKTVLHKVKDFHLKFLEQYS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD30-1", "uniprot_id": "ALAT2_HUMAN", "id": "Q8TD30-1", "name": "Alanine aminotransferase 2", "aln": "--------------------------------------------------MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRR---ERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRG-IKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPS--------FPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEA-KDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMG---PEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDP9-1", "uniprot_id": "A0A8M1NDP9_DANRE", "id": "A0A8M1NDP9-1", "name": "alanine transaminase", "aln": "--------------------------------------------------------------------------------------------MR---EKTLTMDTLNPQVKAVEYAVRGPIVIKAGEIERCLEEG-GTKPFSEVIKANIGDAHAMGQQPITFLRQVVALCTFPELMESPS--------FPEDAKWRARRILQGCGGHSLGSYSASAGVEYIRKDIAAYIEQRDEGVPSNWEDIYLTTGASDGIMTILRLLVSGKDSSRTGVMIPIPQYPLYSAAISEMDAVQVNYYLDEDNCWALDINELHRAYQAA-KQHCQPRVICIINPGNPTGQVQSKKCIEEVLHFAYEENLFVMSDEVYQDNVYAPDCQFHSFKKVLYEMG---PEYYNSVELASFHSTSKGYTGECGFRGGYMEVINMDPEVKAQLVKLLSVRLCPPLSGQAAMDVIVNPPQPDEHSYQQFHQEKSSVLGALAEKAKLTEEILNAVPGIKCNPVQGAMYAFPRIFIPPKAMEEAKTLGMQPDMLYCLRLLEETGICVVPGSGFGQKDGTYHFRMTILPSKEKLKVLLGKLRDFHVSFLKEYSALE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD9-1", "uniprot_id": "Q9VYD9_DROME", "id": "Q9VYD9-1", "name": "alanine transaminase", "aln": "MFKNRKIMSRMLIKPAAATVSAALQQHQRQQQQYVIRRWKSFLHNNSNNANRRAAKSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGPLVIRAGEIEKELEKG-VKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPD--------YPEDVKKRACAILNGCQGQSVGSYTDSAGLEVVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEA-KKVCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYEMG---DPYRN-LEMVSFLSTSKGYLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTWHFRSTILPQTDKLKLMMEKFRVFHAEFMKKYK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52892-1", "uniprot_id": "ALAT2_YEAST", "id": "P52892-1", "name": "Inactive alanine aminotransferase", "aln": "---------------------------------------------------------------------------MTMTHQQDLKGVFTAKDLDFKPAGKITKKDLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTRQVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDIGG-SIGAYSHSQGVPGIRQTVADFITRRDGGEPATPEDIYLTTGASSAATSLLSLLCKD---SQTGLLIPIPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYGITIISDEVYQENIFN-DVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLLYETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPG---TKWIQDWKEFHQDFFSKYRN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :*. . :*****.: :* ::. *. . ** ::*.****: : :.*:*:** **::*: . :: :. *. ** :*: * *:*:*: * *: :*. :* :* :** .. ::::*: *** . ::* :: .*:::.*******:* : . : ***:*: *: : *:.: * :. * .: :******** * :.: * : :* . : :::*****:*:: . .* *:*** :: ::.*: * ** : .*** ****:*::.: :: : * :: :*. .**. :. :*.** . : *. *: : : :*.: . :: * : ***** **:: :* :*: :: ** ::. *** :*** ********: **:*.* *:*. : . ** * :* ", "identical_positions": 140, "similar_positions": 150, "identity": "23.65%" }, { "cls_id": "homologset.agr.SGD:S000002522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FGS0-1", "uniprot_id": "F7FGS0_RAT", "id": "F7FGS0-1", "name": "Large ribosomal subunit protein bL34m", "aln": "KGQQPIPRTAARVVPTTLGRPLPVAEAENYNSQKIRGGQNVIHTAGDYTRSPPPGYFGELHATEDRVSSLSSSAGVELQLPKCPVAIGGTTFPRRHCQGAQSVGTEVDPDDQASDPPLDMAFLAR-CFGGQACRSVILLSGRYLQSRVWMGLPDAWS-LSLQQVRGRTRGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N91-1", "uniprot_id": "RM34_MOUSE", "id": "Q99N91-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-----------------------------------------------------------------------------------------------------------------------MAFLAR-CFGCQACRSVALLSGRYLQSRVWMGLPDSWPLLSLQQARGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ48-1", "uniprot_id": "RM34_HUMAN", "id": "Q9BQ48-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-----------------------------------------------------------------------------------------------------------------------MAVLAG-SLLGPTSRSAALLGGRWLQPRAWLGFPDAWGLPTPQQARGKARGNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E959-1", "uniprot_id": "RM34_DROME", "id": "Q0E959-1", "name": "Large ribosomal subunit protein bL34m", "aln": "---------------------------------------------------------------------------------------------------------------------MLQGMLQRTCLAVVSTAQTLIVRDKHAFNRAVL--------------KPKVRCHFPKPMEVKRINVHGWNARMSTPEGRRVLMNRILKGRHNLSH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04598-1", "uniprot_id": "RM34_YEAST", "id": "Q04598-1", "name": "Large ribosomal subunit protein bL34m", "aln": "-------------------------------------------------------------------------------------------------------MPLFARLCQPQSRRMFSSISSFSALSVLRPQTGMLLNSSPLKTPSFTPLGFG----LIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWFLSH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: :: . : : * : :* :** . .*: * .: * ::: .* **** ***", "identical_positions": 15, "similar_positions": 21, "identity": "7.08%" }, { "cls_id": "homologset.agr.SGD:S000002523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFE9-1", "uniprot_id": "D3ZFE9_RAT", "id": "D3ZFE9-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAARYLGRVMLPWNTCVRRGTPSLTYCALFLFLDTFLIHHQRHSLCKMAHQAAFYPCSLNSLLPNRHFAAAAAKS---ARKNKKGAKEKTS-DEKPVDDIEKIKSYTYMESEPEDDVYLKRLYPRRIYEVEKAIHLLKKFQVLDFT-NPKQGVYLDLTLDMALGKK-KKVEPFASVIALPHPFSS-EVNKVAVFTGNASEIKIAEENG-AAFAGGADLVKKILDDEVVV---DFYVAVPEIMGELNPLRKKLKKR---FPKATRNSIGRDIPKMLELFKTAHEIMVDEER----QNFLSTKIATLDMPSDQLAANLQ---AVINEVCRHRPLNLGPFVVRAFLRSS-TSEGLLLKTDSLLPKEAGNAEAA----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N96-1", "uniprot_id": "RM01_MOUSE", "id": "Q99N96-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAVR-----------CLRR----------------VLIHHQRHCLCKMASQASLYPCSVNSLLHNRHFAAAAAAATKPARKIKKGAKEKTS-DEKPVDDIEKIKSYTYMESDPEDDVYLKRLYPRRIYEVEKAIHLLKKFQVLDFT-NPKQGVYLDLTLDMALGKK-KTVEPFASVIALPHLFSS-EVNKVAVFTANASEIKIAEENG-AAFAGGTDLVKKIMDDEVVV---DFYVAVPEIMGELNPLRKKLKKR---FPKATRNSIGRDIPKMLELFKTAHEIMVDEER----QNFLSTKIATLDMPSDQIAANLQ---AVINEVCKHRPLNLGPFVVRAFLRSS-TSEGLLLKTDSLLPKEAKTTEAETEETQTAEAA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYD6-1", "uniprot_id": "RM01_HUMAN", "id": "Q9BYD6-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAAVR-----------CMGR----------------ALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSA----KKTKKGAKEKTP-DEK-KDEIEKIKAYPYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFT-SPKQSVYLDLTLDMALGKK-KNVEPFTSVLSLPYPFAS-EINKVAVFTENASEVKIAEENG-AAFAGGTSLIQKIWDDEIVA---DFYVAVPEIMPELNRLRKKLNKK---YPKLSRNSIGRDIPKMLELFKNGHEIKVDEER----ENFLQTKIATLDMSSDQIAANLQ---AVINEVCRHRPLNLGPFVVRAFLRSS-TSEGLLLKIDPLLPKEVKNEESEKEDA------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYL4-1", "uniprot_id": "A0A8M1NYL4_DANRE", "id": "A0A8M1NYL4-1", "name": "Large ribosomal subunit protein uL1m", "aln": "---MAAPAR-----------SVLR----------------VLPRCQSLLFTNRAPSVSCNSLTAHRQQSARSYAATKKKE-----KKEEAVKEKVVKERKIIDDKDRHKPFGLTAWAPVDDVYMVRYYPRPLYELTVAIDMLKSFQKLDFS-AENQPIYINLRLNMKLEKK-RKLDPFVRTIHLPHPFKS-DINKVVVFTEKPDQARIALENG-AAVAGGVELFEKILADEITA---DFYLAEPDILPKLVPLKNKLRKK---FPKSKRGTVGINIPRMLELFKTGHEYIVED-------IYVNTEVATLDMPKEHILENIH---TILKDVASHKPAEFGPIIDRAIVCSR-SSEGLHLKLEELLPQEEKMA-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHT5-1", "uniprot_id": "Q9VHT5_DROME", "id": "Q9VHT5-1", "name": "Large ribosomal subunit protein uL1m", "aln": "MQSILS--------------SMR-------------------ALALRQSTVEPLRLLHLSAVSEAARKGTREKARKKKVK---VEVKKVGFIPHNQRNKKINVKRADKHVDDSWKQVPKDDCYVGRYYRWPVYSVQEAIQCHRETHHPSMYNVPNAPLNLDIELNMQAEKITRFVDNFQRMAMIPHKFDHGEERKIIVFTKGNNEVLEAREAG-ASLVGGVELIKDITSGELLLSDYQYVIAHPNILAELVALRGLMKRK---FPNPKSETLGTNLAEMIVKFSSGISYSAAKDEYQQNFGLITASVGTLDMDVQKLEENIK---FLLQDINTMRPKREGRFITRVLLKSPPSSEQLKIDPFVYVPEMWDKSTAKVKRDGAKKQTEPAEPQEAVASN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04599-1", "uniprot_id": "RM01_YEAST", "id": "Q04599-1", "name": "Large ribosomal subunit protein uL1m", "aln": "----------------------------------------------------MLSVVAIPKICVTGPARRCFFHTAKKLY-------ADDYKPAAMSSNAPSLTKDQAKKRELKRLVQRKAEAKRPATASPLYMP--VTKALRYLRAAEVG-RPQSQQTINLTTLVVGERG---TAPLSGSVTFPKPLRY---IKIAAFTNDESKLEELREKYPNHLIGGADLVAKIKSGEISVD-FDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTVSDDISSLLQESLGSMPFRQRGNS-------ISIGVGKCYFTDREILQNIISARAAFKTAVDNQKSKKPNILSKTTLSST-HGPGIVIDFA-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . :* . . : : .. : ::: : : : :* : *: .** .: * . **..*. .* .*: : .* *:*: * : *. . ::. ::. :: . : :.. : .: *: :: : . :: :. : * . : :. ", "identical_positions": 18, "similar_positions": 68, "identity": "4.53%" }, { "cls_id": "homologset.agr.SGD:S000002524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPG7-1", "uniprot_id": "EIF2D_RAT", "id": "Q5PPG7-1", "name": "Eukaryotic translation initiation factor 2D", "aln": "MFAKAFRVKSNTAIKGSDRRKLRADVTVAFPTLGTDQVSELIPGKEELNVVKLYAHKGDAVTVYTSGGNPILFELEK--NLYPTVYTLWSHPDLLPAFITWPLVLEK-LVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGN-RAPVAVGVAAMST-AQMLASGLKGKGISVLHTYQDHLWRSGDKSSPPAIAP--LDPTDSCEEK----ADLGLHGNLRSLSLEGEEENGQVPNP-------EASDDPNSRALSQDSVDGKPLQEQMDELLEQCFLHALKSRVKKADLPLLTSTLLGSHMFSCCP--EGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFIVPEP----SLASQTVQEGSREKPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRRIITDYAKRNNLVDADNRNLVKLDPILCDCILEKN-EQHLVMKLPWDSLLTRCLKNLQPAYQVTFPGQEPIIK----KGKLCPIDITLVLKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61211-1", "uniprot_id": "EIF2D_MOUSE", "id": "Q61211-1", "name": "Eukaryotic translation initiation factor 2D", "aln": "MFAKAFRVKSNTAIKGSDRRKLRADVTAAFPALGTDQISELIPGKEELNVVKLYVHKGDSVTVYTSGGNPILFELEK--NLYPTVYTLWAYPDILPTFITWPLVLEK-LVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGN-RAPVAIGVAAMST-AQMLASGLKGKGVSVLHTYQDHLWRSGDKSSPPAIAP--LDPTDSCEEK----VHLGLQGNLKSLTLDGEEENGQVPLR-------EASEDTSSRAPSQDSLDGKPLQEQMDDLLLRCFLHALKSRVKKADLPLLTSTLLGSHMFSCCP--EGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFVIPEP----SLTSQTVQEVSREQPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRKIITDYAKRNRLVDADNRNLVKLDPILCDCILEKN-EQHLVTKLPWDCLLTRCLKNMQPAYQVTFPGQEPILK----KGKLCPIDITLALKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41214-1", "uniprot_id": "EIF2D_HUMAN", "id": "P41214-1", "name": "Eukaryotic translation initiation factor 2D", "aln": "MFAKAFRVKSNTAIKGSDRRKLRADVTTAFPTLGTDQVSELVPGKEELNIVKLYAHKGDAVTVYVSGGNPILFELEK--NLYPTVYTLWSYPDLLPTFTTWPLVLEK-LVGGADLMLPGLVMPPAGLPQVQKGDLCAISLVGN-RAPVAIGVAAMST-AEMLTSGLKGRGFSVLHTYQDHLWRSGNKSSPPSIAPLALDSADLSEEKGSVQMDSTLQGDMRHMTLEGEEENGEVHQAREDKSLSEAPEDTSTRGLNQDSTDSKTLQEQMDELLQQCFLHALKCRVKKADLPLLTSTFLGSHMFSCCP--EGRQLDIKKSSYKKLSKFLQQMQQEQIIQVKELSKGVESIVAVDWKHPRITSFVIPEP----SPTSQTIQEGSREQPYHPPDIKPLYCVPASMTLLFQESGHKKGSFLEGSEVRTIVINYAKKNDLVDADNKNLVRLDPILCDCILEKN-EQHTVMKLPWDSLLTRCLEKLQPAYQVTLPGQEPIVK----KGRICPIDITLAQRASNKKVTVVRNLEAYGLDPYSVAAILQQRCQASTTVNPAPGAKDSLQVQIQGNQVHHLGWLLLEEYQLPRKHIQGLEKALKPGKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04600-1", "uniprot_id": "TMA64_YEAST", "id": "Q04600-1", "name": "Translation machinery-associated protein 64", "aln": "MFKKEPHIKALSNLKNSERKKLLQTFQKQTNNE------EYSFRTSTIKQTNFNGQKSVGTVYTDENNTPILFKEKHKEQLFPTVYSCWEYPALLPIVLTHGFVIEEHLFNGANLMISGSIPPFD--PRCKIGTLCGIASKQAPETVLAIGIVELDLPSFDKVIGETGVAVKIIHHFNDGLSKVFKMKLEPPFVLS----------------TQSKDNNISSKQIESSEQIKAVEKEQ------EDVKEASVDVEEIAEVLDHFTVSDVDYFITRALYYTLTQ-DKGLELPISASNFISNHIMRNLPPIDHNEVNVKKTSWKKSAKFLKHFEKEGFLKLKGKGDDLT-IVGKNTDKDELKNFVPYKLGCSKSATESRESTTSKEKTSGMMYSLTLYKPFNLAKDLLKEVNLASHTYYTSQDIRSAVSQYISVKNLADTKDKGKVIMDDLLFDMVNKKKKVLNASRIIARGEILHPLLTNNFTEFYQIFKSDDTLLFKAPMKGSLPHIKIITEMKIGRKVITRVSNFEVFQVDPESLAADLRKICSGSTTISESQ-TFKCAEVQVQGPHGQSI-IDHLNKLGIPSKWIDFENKLKKKKRK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ::*: : :*.*:*:** . * .. :: .:: :*. ... ....****: :: :*:****: * :* :** . * :*:*: *..**:**:.* : * *: : * **.*: .: :*:*:. :. : . * .* ...::* ::* * : . . *.:. ..:: ::..*: * * .:.. . . .: .::* :: :.: ::*. * :**: :*.::..*:: * : .::::**:*:** :***:::::* ::::* ...: **. : : .:..*: : * :.. . *:*:. .** . *: * . . : ..::* : :* . : *.*:.::. * :* :* * : :*: : :. . :* * : . : : .::.:: ** : *.* : .* :* * *:*.: :** *:** *:: *..** :. : : .. :**:** : : : *:: :* * *: :* * :* ", "identical_positions": 118, "similar_positions": 218, "identity": "19.67%" }, { "cls_id": "homologset.agr.SGD:S000002525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUB7-1", "uniprot_id": "D3ZUB7_RAT", "id": "D3ZUB7-1", "name": "Anaphase-promoting complex subunit 4", "aln": "MLRFPTCFPSFRVVGEKQLPQEIIFLAWSPKRDLIALANTTGEVLLHRLASFHRVWSFPPNESTGKEVTCLAWRPDGKLLAFALADTKKIILCDVEKPESLHSFS--VEAPVSCMHWMEVTVESS-VLTSFYN-AEDES---NLLLPKLPTLPKNYNSTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCIALCLSSDLKSLSVVTEVSSGGES-EVSYFQLETNLLYSFLAEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKTTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDASSIEDAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVAMLRMT-----EDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKG-------KYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSNHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIG---RSMNQAICIPLYKDARSMDGARRLLKFPFLWNNKTSNLHYLLFTILEDSVYKMCILRRHTDSSQSVSNGLIGIKFGSFTYATTDKVRRS------TYSCLDAQFYDDETVTVILKDSMGREGRDRILVQLPLSLVYNSEDSDEYEFTGTCSTRLDEQGSIIPTRTMHFEKHWRLLESMKAQYVAGNGLRKVSCVLSSNLRHVRVFEMDIDDEWELDESSDDDEEAAGKPVKIKEEVLSESETEAHQD-AAALDSDVVIKVEKLDPELDS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W96-1", "uniprot_id": "APC4_MOUSE", "id": "Q91W96-1", "name": "Anaphase-promoting complex subunit 4", "aln": "MLRFPTCFPSFRVVGEKQLPQEIIFLAWSPKRDLIALANTTGEVLLHRLASFHRVWSFPPNESTGKEVTCLAWRPDGKLLAFALADTKKIILCDVEKPESLHSFS--VEAPVSCMHWTEVTVESS-VLTSFYN-AEDES---NLLLPKLPTLPKNYNSTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCIALCLSSDLKSLSVVTEVSSGGES-EVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKPTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEDAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVAMLRMT-----EDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKG-------KYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSTHLKESPLLFPYYPRKSLHFVKRRMENVIDQCLQKPADVIG---RSMNQAICIPLYKDARSMDCARRLLKFPFLWNNKTSNLHYLLFTILEDSVYKMCILRRHTDISQSVSNGLIGIKFGSFTSASADKVRRS------SYSCLDAQFYDDETVTVILKDSMGREGRDRILVQLSLSLVYNSEDSDEYEFTGSYSTRLDEQGSIIPTRTMHFEKHWRLLESMRAQYVAGNGLRKVSCVLSSNLRHVRVFEMDIDDEWEIDESSDDEEEAGGKPVKIKEEVLSESETEAHQD-AAALDPDVVIKVEKLDPELDS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX5-1", "uniprot_id": "APC4_HUMAN", "id": "Q9UJX5-1", "name": "Anaphase-promoting complex subunit 4", "aln": "MLRFPTCFPSFRVVGEKQLPQEIIFLVWSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFS--VEAPVSCMHWMEVTVESS-VLTSFYN-AEDES---NLLLPKLPTLPKNYSNTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGAS-EVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVAMLRMT-----EDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKG-------KYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSSHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIG---KSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRS------IYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDESSDEEEEASNKPVKIKEEVLSESEAENQQAGAAALAPEIVIKVEKLDPELDS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7D6-1", "uniprot_id": "A0A8M2B7D6_DANRE", "id": "A0A8M2B7D6-1", "name": "Anaphase-promoting complex subunit 4", "aln": "-------MPAFRQVGEKQLPNPILYMAWCPKRDLIALANTTGELLLHRLANFHRVWSLPPNENTGKEITSLAWRPDGKVLAFSVGDTKQVVLCDAEKAEILHLFP--VEYPASCMHWMEVQDDSS-TLTSFSE-SEDES---SRFLPKLPTLPKSYSTTSKIFSEEKSEEVTNLLGEVRLNILVVGGPSGFVELYAYGLYKIATLSGILGTCRSLGLSSDLKSLSVITEIRSTDDNPEIRYIQLDTGLLSSCLPELTKMARKFTHISTLLQYLRVSLTCMCEAWEEILMQMDLRLTKFVQEKNTSTQVQDEFLELLLWGHASPELQALLMNQLTVKGLKMLGQSIDSSYSSIQKLVISHLQSGSEALLYHLSEVKGMALWKQKFQPLGLDPSDIEDAIVAVGSFTLKASELLQVIDKSMKNFKAFFRWLYVAMLRMS-----EDHVPPELNKMTQKDLAFVADFLSEHFSANEELFDRKG-------KYFNVERVGQYLKDEDEDLVSPPNMDGNQWVTFVKQSTHLKDSPLLFPTYPQKSLHFVKRLMEASIDLCLQKPAAVIG---DSVKQAVCLRLYTVPESSENTPRLFELPSLWNDKKAAMHYVVFCMPEISPSKIYILRRPTDPNRSVPNGLVALNLNTPLNSSIDDETPAPASVDYSYSCLDARFYDDETLTVVLRRLEDDENKMRVLAQLPL----NSAMSWDEEFSWDLSLRLEQQTEGIPVQGVAWGNQSREMDNISAQFVAVNGIRKVACVLSANLRHVRVFEMDAEEEEDEEERADESQEMSSDQDRIEDTKTNESDAVEGGRVEDAQVSGQGPR-DSLDDTAGSDTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W395-1", "uniprot_id": "Q9W395_DROME", "id": "Q9W395-1", "name": "Anaphase-promoting complex subunit 4", "aln": "----MAQTSSMKLLGARNMSCIVERMEWNNKMDLIAYGTEKGEVVIQRLN-WQKIVTFP-TPGEDVRVRSLSWQMDETLLAVGYSN-GKVALLDAESGTIISGLI--YEDDIKKVYFSKAINSQE-NLGTYTCNVKDKH---RRFLPKLQPMTN-IDPCLKTLDQKS----FPKGSPCFLVVIMRSGKVHLLLLGALQAGSIDLTQHILHPHEFDVYDVRMNGDCNAIYALLRDGQ-ELILLHFQNQVLQDCMAPMLELATHCAHILETKNYINDTQQCLTEAWETVQLEMDNKLTRYANSQ-PYGVISAHFLELHVFGFATFEVEEFLFETLSEKGFKKIANSVDLSLSNLQSLVFKQLNGAAINMFYFLNTIAGFGRMSHFFESL-ISPDVANEAMRACGGFVLKVHELQRTIDTLAYDMKLFHAWMIFTILRLSHQEIPDDLVLTEEENIAMADFICAMEPELDDRSDDEDELDSQSQTPPPARSKFNLERVGQYLDNAYLTQLYPRDP-VQLWEEMVTDNECLSNCKLFVPHDVNLSLVQQRDKMFNAIDAVFHKPTESISGSFKVSSTVICNDLPPMEPGEDHRDRDLVTCTYYVNEASRTDMLACTISGQ---EAMILEFSRAGDECVRCTRITLEPGLFTTSVSEDFCYLR--------FVDLQFYNESSLSILAQSINAGPGMRPHSFFIQFSLTAALNYSTQHRMG--PLVKLSEATVSQSIHDIADGAAFKGLDGFSDMLAVS-GSRKVATVLSDRKRKMTIFEMEIEEEEDDTEMSQASFLDISKESVLAGVPDAEKQEA-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04601-1", "uniprot_id": "APC4_YEAST", "id": "Q04601-1", "name": "Anaphase-promoting complex subunit 4", "aln": "----------------MSSPINDYFIDYNPLFPIFATRIAKG-LAIYRVSDHARLAVIPIRNIN--LVANYDWDTTTGKFLSIFFKDGTIRIHDIFKDGRLVSFLRIPSTKISKGIWDRIPLRYEPNNRDFACNIIDDLPKLIRFVKDSKRINIVPYTQPNSLWRGPDEDDLDSNEKLDVHVVFNEGNDKITVFFNGDYAVFLSVDNIENENSLKSIIKVQDGFYQCFYEDGTVQT-----------LNLGPLLQSKSSVNLLNYIMVIKELIGYMLTHLEFINRELATPYLDFVKRLCDEAYGYGKLKSELEALFLLGEISCDLEDWLCNSVGEKNFKRWKYLGCEAYQKTVQILTLIFVPACERIIIYVEKLRAILQAFSIQNKLSYTSD-------------------LTAVEVLLKSSQKLLTMTLNSIIGLG-----------RDETLFEKFFIWFNDRLHEALDEDYK------------------------LKFQFEDDLYFGYDLLSYFDRILSKKGTEPSS--------IIDVKLYRDLINSMSDMEKDIAQSNVN---SHIQQHILVDLKTDVFAQKYP-------------SSQINLLDAIKLPKHNYIVYLIQVTKHNSAQEPFSEENKKK------------------------LYIGTLKDENLGIISKES-------------------SVKIPALFKSYRLSSTRFVPNRVHSLLRDIGLSDS-----NYHSSHVTDYRGENYENEEDDGTIAIPAYIRENRENDDFIACTAKVSVDGRSASLVFPKEKQNV--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : ::* * : : *: :: :* : * : . : : * . : : . . : . . : *. :: . : : : . : ::. * : : : * .. : . : . :* : : : . : :.: :. :. .: * : * : ::: * : : *.:* : .. .:: : .. :: .:. : .: : * . .:: . : : ::: : . :.: : : : . . *. : . : :: .. .. .: : : * . . :. . : * . . : . : ::. . : : .:..: :: : . . :: : : . .. .: . : : : :: : : . : : ", "identical_positions": 19, "similar_positions": 170, "identity": "2.26%" }, { "cls_id": "homologset.agr.SGD:S000002527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A140UHW6-1", "uniprot_id": "A0A140UHW6_RAT", "id": "A0A140UHW6-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "MSLARTILWLSRPLRPARSLCRAQFMERKAQEPPSPPTMENGTRSC-EERPPAAPVATVTEGAARISFPSANEVFYNPVQEFNRDLTCAVITEFARIHLGAKGIQIKVPGEKDLQKIAVDLSDQEEE--TAGQNENLAPGDQPRTAAVGEICQEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELNGVAHLVQPNQADARMLMYQHQKASERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYVRVFVRVFTGQAKVKSSASKQALVFQCVGCGAFYLQRLGKASGDPGG----RVKFSAACGPPVSPECEHCGQRHQLGGPMWAEPIHDLDFVGQVLEAVTTNPGR----FHTSTRIQGVLSVVTEELPDVPLYYTLDQLSSTVHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDASPEALWDIMRCWEKECPVKRERLSESSPAFRILAVEP-----RLKANFN--IREDANPSS------RQRGLKRFQANPEANWGPRPRARPGGKAASEGLAERRRLLQNKRKEPAEDPAQRAARLKTFPCKRFKEGTCQLGDQCCYSHSPAAPVASGDIPITDCPETTTKLSPEPEAAHGSIPGPGVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TX08-1", "uniprot_id": "TRM1_MOUSE", "id": "Q3TX08-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "MSLARTILWLSRPLRPAHSLCRAQFMERKAQKPPSPPAMENGTRSW-EERPPADPVATVTEGAAKIVFPSANEVFYNPVQEFNRDLTCAVITEFARIHLGAKGIQIKVPGEKDSEKIAVDLSDQEEE--TAGKNENLAPGDWPRTAAVGEICEEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELNGVAHLVQPNQADARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCGAFYLQRLGKASGDPGG----RIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGR----FHTSMRIQGVLSVVTEELPDVPLYYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIMRCWEKECPVKRERLSESSPAFRILAVEP-----RLKANFN--IREDANPSS------RQRGLKRFQANPEANWGPRPRARPGGKAASEDLAGRRRLLQNKRKEPAEDPAQRAARLKTFPCKRFKEGTCQLGDQCCYSHSPAAPVASGDIPIEECPETTTKISPGPKAAAGGIPGPGVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXH9-1", "uniprot_id": "TRM1_HUMAN", "id": "Q9NXH9-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "--MQGSSLWLSLTFRSARVLSRARFFEWQSPGLPNTAAMENGTGPYGEERPREVQETTVTEGAAKIAFPSANEVFYNPVQEFNRDLTCAVITEFARIQLGAKGIQIKVPGEKDTQKVVVDLSEQEEEKVELKESENLASGDQPRTAAVGEICEEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHLVQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSG----RAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGR----FHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEP-----RLQANFT--IREDANPSS------RQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADA-APDCPETSNQTPPGPGAAAG----PGID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK89-1", "uniprot_id": "TRM1_DROME", "id": "Q9VK89-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "-------------------------MEVDEEKPQIIAENPN--------------ENVIRERNAEIVS--GGNVFYNPVQEFNRDLSIAALNVYRQRLTKER-------SEKALKKQRKKVKEQEDE------KTTPVPED-PPVYEAGTRYEDGLRILEALAATGLRSIRYAQEIAGVRQIVANDLSRQAVASINTNIRHNKVEELIEPSHSDAMTLMYLSTQPEKRFDAVDLDPYGCPNRFLDGAMQCLVDGGLLLVTATDMAVLAGN-APEACYVKYG-SVPLRMKCCHEMALRILLHCIESHANRYGKYIEPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIYQCTGCETFTLQPLGITKPNPTAGNPQQLKFGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEFVQDLLTAVQETTLQS---LGTQRRIVGVLSMVQEELQDVPLYYTPDKLCCVLKLEIVPMLKFRSAILHAGYRVSYSHASKNSLKTNAPPAVLWDILRSWSKRHPVNPERMIPGSPLAAILSKEC-----TAVYEFDE-LHPEANPKS------RKSALSRFQENPTPHWGPGTRAT--------IMIGDNKLPKSYRNQNKK--------------QRHKASEQQAED---DQQDTPQAVDEYDGDVEHLPKQ-----PKLEATA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15565-1", "uniprot_id": "TRM1_YEAST", "id": "P15565-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial", "aln": "---MEGFFRIPLKRANLHGMLKAAISKIKANFTAYGAPRIN-----------IEDFNIVKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECG--QKRNNKKSKKKRCAETNDDSSK------RQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVPPLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDEK-KDLSKMNPNTTGYKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKARPNTS------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * : * *.* *****:*:*****: : :. : . .:* :* . .::..: . . . . : :.:**.*:*:***:**:* *:. ::.::*** .** :. *:. * * .:::*. ** *** ::*..:****** *:*.*:*.: :***: **.**::***** * *: ** : : .. ** ***::*: :. * * : : ****:* ***:*:**:* .. : * *. ::* * :: * ** . *:. . **.* .:*:.* ::*.**::: *:*: :*: :* * ** *:**: :** * *:*:: :::...:: : : :. :.: .:. * :** .::**:*. .:* ::: ... . .:: :. **: :: : .* .* *: : *:* ** :*** .*. ", "identical_positions": 140, "similar_positions": 168, "identity": "20.32%" }, { "cls_id": "homologset.agr.SGD:S000002528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642A5-1", "uniprot_id": "DPOE3_RAT", "id": "Q642A5-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKG-KKEASEQKKKDKDKK-------------------DCEEQDKSREEE-DEDEERLDEEEQNEEEEVDN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRF9-1", "uniprot_id": "DPOE3_HUMAN", "id": "Q9NRF9-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKG-KKEASEQKKKDKDKKT------------------DSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKP7-1", "uniprot_id": "DPOE3_MOUSE", "id": "Q9JKP7-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MAER----PEDLNLPNAVITRIIKEALPDGVN---ISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFITPLKEALEAYRRDEKG-KKEASEQKKKDKDKK-------------------DSEEQDKSREVE-EEDEERLDEDDQNEEEEIDN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V444-1", "uniprot_id": "DPOE3_DROME", "id": "Q9V444-1", "name": "DNA polymerase epsilon subunit 3", "aln": "-------------------MVER----IEDLNLPNAVIGRLIKEALPESAS---VSKEARAAIARAASVFAIFVTSSSTALAHKQNHKTITAKDILQTLTELDFESFVPSLTQDLEVYRKVVKE-KKESKASKK---DSN-------------------TAENANASATATAEEAPE-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04603-1", "uniprot_id": "DPB4_YEAST", "id": "Q04603-1", "name": "DNA polymerase epsilon subunit D", "aln": "MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLAREVPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHIGHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDEIEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :** :*::.* .: :*. :. . :.*:* *: *.*:**. . : :* . .:*: ...*:*.:: .: .. : .: : *: *: : *** . : * . *: . : :. : ", "identical_positions": 24, "similar_positions": 55, "identity": "12.24%" }, { "cls_id": "homologset.agr.SGD:S000002529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P4S6-1", "uniprot_id": "SIK3_MOUSE", "id": "Q6P4S6-1", "name": "Serine/threonine-protein kinase SIK3", "aln": "----------------------------------MAAAAASGAG-----------------GVAVAGAGGAGPAG---RLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIID---------------------------KSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTSPTAEIPPDLQRQLGQQSFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQ--EYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A0T3-1", "uniprot_id": "A0A8I6A0T3_RAT", "id": "A0A8I6A0T3-1", "name": "Serine/threonine-protein kinase SIK3", "aln": "----------------------------------MAAAAASGAG-----------------GVAVAGAGGAGPAG---RLLPPPAAGPPAAPAAVPPAACPPRPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIID---------------------------KTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHRWMKLGDADPNFERLIAECQQLKEERQAEPLNDEVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKNKTLRPGALPSTPQAMTFQAPVNIQAEQTGTAMNISVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMDEMQKLLPGFPGANPQTPFLQVAPNMNFMHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQS------------------------------------------------STYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLERMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPTLLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMISSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTTAGSAGRGIPISPSASQIQMQHRTSLMAPFGYGHRPLSKQLSADSAEAHSLSMNRFSPANYDQAHLHPHLFSEQSRGPPSSYSPSTGVGFPPAQALRVPPLDQFPTFPPSAHQQP-HYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQQQEYHELFRHMNQGDAVSLAPGLGGQNMTEHQALSYQNADSYHRHHTSPQHLLQIRAQDCISQGPLPTPTRGYARQSPLMHSESMEEDCLCEGVKEGFADKSSSTLTKGCHDSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVIGNCMERSSPGQAMELPDHNGLGYPARPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPALGDGSQHLN-SRYPATCVTDIMLNHKHPEVSFSMEQAGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13185-1", "uniprot_id": "KIN1_YEAST", "id": "P13185-1", "name": "Serine/threonine protein kinase KIN1", "aln": "MDDYHVNTAFSMGRGNQQDDGNSESNSMHTQPSTMAPATLRMMGKSPQQQQQQNTPLMPPADIKYANNGNSHQAEQKERQVELEGKSRENAPKPNTTSQSRVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFNGP--------------PPSYLPKRVPLTIEMLDINVLKEMYRLEFIDDVEETRSVLVSIITD---------PTYVLLSRQYWTLAAKMNAESSDNGNAPNITESFEDPTRAYHPMIS--------------------IYYLTSEMLDRKHAKIRNQQQRQSHENIEKLSEIPESVKQRDVEVNTTAMK-------SEPEATLATKDTSVPFTP-------------KNSDG----------------TEPPLHVLIPPRLAMPEQAHTSPTS----------------------------------------------------------------------------RKSSDNQRREMEYALSPTPQGN----------------------DYQQFRVPSTTGDPSEKAKFGNIFRKLSQRRKKTIEQTSVNSNNSINKPVQKTHSRAVSDFVPGFAKPSYDSNYTMNEPVKTN---------DSRGGNKGDFPALPADAENMVEK-----------------QREKQIEEDIMKLHD----INKQNNEVAKGSGR-----------------------------------------EAYAAQKFEGSDDDENHPLPPLNVAKGRKLHPSARAKS-VGHARRESLKY----MRPPMPSSAYPQQ-----ELIDTGFLESSDDNKSDSLGNVTSQTNDSVSVHSVNAHINSPSVEKELTDEEILQEASR-----------------------------APAGSMPSIDFPRSLFLKGFFSVQTTSSKPLPIVRYKIMFVLR-----------------------KMNIEFKEVKGGFVCMQRFSSNN--------VAAKREGTPR------------SIMPLSHHESIRRQGSNKYSPSSPLTTNSIHQRKTSITETYGDDKHSGTSLENIHQQGDGSEGMTTTEKEPIKFEIHIVKVRIVGLAGVHFKKISGNTWLYKELASSILKELKL----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.*: * .: *. *.: * * : . . ** . ..: .: .: :* :*: .*:* *.:. ** *.* *: *:**:: * : : .. *: :**..: ::* **** **::: .. :*:: **.***:::*::: ** : *::**: : *.:*: : *..******** **:::. . :*** ***:**:: . : *:*:*** :*****::.: * **:**:**:****:***** :***... . *: :: .**.. * .:* * *: :***:**::* :::*: .*:** * .* . * . : : * *:.: ** .: .*. : *.: *:: * * : * *: * :* ::.:.*.* *:: . : .. : :*. : **: . *. *.: : :: : :. . :* * . : :* . * *: *: .* : *** .** .: *. *:. . *. . *: **. : ** * : :. .. :: :. :*::: * . : :. . . *:*. **. : *. . *.: **: :.:* :: . . . .:* .**:.. : :: *: .* : ::*:: :.: . .* .:** .: ::*. :: *: * * * :.* .* ..: **.. ::*: *.:*.** * . :: .:*..: : . . . **:..* : *::: *: * **. . .: ::* :. * : :.* ::: : : : : : :* ** . : .: :.:. * *. .* * .*: : . ** .. ..: *.:.: ... : *.: * . . : .: *. : .. . : :: : *:: * * :*. *:.* * : ", "identical_positions": 226, "similar_positions": 354, "identity": "15.56%" }, { "cls_id": "homologset.agr.SGD:S000002532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD66-1", "uniprot_id": "ABHD4_MOUSE", "id": "Q8VD66-1", "name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "aln": "-------------------------------------------------------MADDLEQ-QPQGWLSSWLPTWRP--TSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVS-------PEQKDRTPLVMVHGFGGGVGLWILNMDSLSA-RRTLHTFDLLGFGRSSRPTFPRDPEG-------------------------------AEDEFVASIETWRETMGIPTMILLGHSLGGFLATSYSIKYPERVKHLILVDPWGFPL---RPT--------DPSEIR--APPTWVK-AVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGANTWIDTSTGKKVKMQRPDSY-----VRDMEIEGASHHVYADQPHIFNAVVEEICNSVD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAW4-1", "uniprot_id": "D3ZAW4_RAT", "id": "D3ZAW4-1", "name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "aln": "------------------------------------------MGWLSSTRQGLFTMADDLEQ-QPQGWLSSWLPTWRP--TSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVS-------PEQKDRTPLVMVHGFGGGVGLWILNMDSLSA-RRTLHTFDLLGFGRSSRPTFPRDPEG-------------------------------AEDEFVTSIETWRETMGIPTMILLGHSLGGFLATSYSIKYPERVKHLILVDPWGFPL---RPT--------DPSEIR--TPPTWVK-AVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGANTWIDTSTGKKVKLQRPDSY-----VRDMEIEGASHHVYADQPHIFNAVVEEICNSVD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB40-1", "uniprot_id": "ABHD4_HUMAN", "id": "Q8TB40-1", "name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "aln": "-------------------------------------------------------MADDLEQ-QSQGWLSSWLPTWRP--TSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVS-------PEQNDRTPLVMVHGFGGGVGLWILNMDSLSA-RRTLHTFDLLGFGRSSRPAFPRDPEG-------------------------------AEDEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRVKHLILVDPWGFPL---RPT--------NPSEIR--APPAWVK-AVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGSDTWIDTSTGKKVKMQRPDSY-----VRDMEIKGASHHVYADQPHIFNAVVEEICDSVD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAQ5-1", "uniprot_id": "A0A8M2BAQ5_DANRE", "id": "A0A8M2BAQ5-1", "name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "aln": "-----------------------------------------MTRPTPSDRLVLCIKADDVTQ-STSGNWS-WWPSWRP--TSMSLLKSAEAKILACIRNEVWSRFVTLPNQTRIWTLKVTNKTTRKQKEQAAQTPLVMVHGFGGGVGLWIRNLDALSR-SRPVYAFDLLGFGRSSRPSFPADASL-------------------------------AEEQFVSSIEQWRESMGLERMILLGHSLGGYLATSYTIQYPERVSHLILVDPWGFPE---RPQPQVQGSAGQGSEVKRVGPPRWVK-ALASVFSFFNPLAVIRAAGPWGPGLVNRFRPDFKRKFEDLFDDDTMTQYIYHCNAQNPSGEVGFKAMCESLGWAKRPMVQRVHLLPPLMPVSLLYGSLSWVDSSTGNTVAQIRGKSP-----TSVTLIEDASHHVYADQPEEFNRVVENICNTVD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DBL9-1", "uniprot_id": "ABHD5_MOUSE", "id": "Q9DBL9-1", "name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5", "aln": "-----------------------------------------------MKAMAAEEEVDSADAGGGSGWLTGWLPTWCP--TSTSHLKEAEEKMLKCVPCTYKKEPVRISNGNRIWTLMFS-------HNISSKTPLVLLHGFGGGLGLWALNFEDLST-DRPVYAFDLLGFGRSSRPRFDSDAEE-------------------------------VENQFVESIEEWRCALRLDKMILLGHNLGGFLAAAYSLKYPSRVSHLILVEPWGFPE---RPD--------LADQER--PIPVWIR-ALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPSGETAFKNMTIPYGWAKRPMLQRIGGLHPDIPVSVIFGARSCIDGNSGTSIQSLRPKSY-----VKTIAILGAGHYVYADQPEEFNQKVKEICHTVD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QA69-1", "uniprot_id": "ABHD5_RAT", "id": "Q6QA69-1", "name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5", "aln": "-----------------------------------------------MKAMAAEEEVDSADAGGGSGWLTGWLPTWCP--TSTSHLKEAEEKMLKCVPCTYKKEPVRISNGNSIWTLMFS-------HNMSSKTPLVLLHGFGGGLGLWALNFEDLST-DRPVYAFDLLGFGRSSRPRFDSDAEE-------------------------------VENQFVESIEEWRCALRLDKMILLGHNLGGFLAAAYSLKYPSRVSHLILVEPWGFPE---RPD--------LADQER--PIPVWIR-ALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPSGETAFKNMTIPYGWAKRPMLQRIGGLHPDIPVSVIFGARSCIDGNSGTSIQSLRPKSY-----VKTIAILGAGHYVYADQPEEFNQKVKEICHTVD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WTS1-1", "uniprot_id": "ABHD5_HUMAN", "id": "Q8WTS1-1", "name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5", "aln": "-------------------------------------------------MAAEEEEVDSADTGERSGWLTGWLPTWCP--TSISHLKEAEEKMLKCVPCTYKKEPVRISNGNKIWTLKFS-------HNISNKTPLVLLHGFGGGLGLWALNFGDLCT-NRPVYAFDLLGFGRSSRPRFDSDAEE-------------------------------VENQFVESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEPWGFPE---RPD--------LADQDR--PIPVWIR-ALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPSGETAFKNMTIPYGWAKRPMLQRIGKMHPDIPVSVIFGARSCIDGNSGTSIQSLRPHSY-----VKTIAILGAGHYVYADQPEEFNQKVKEICDTVD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04623-1", "uniprot_id": "ECM18_YEAST", "id": "Q04623-1", "name": "Protein ECM18", "aln": "MLLIKRYLMDPESLRRQIMNVYKCYMWKRAFHSNRSLLEVKRREKSLQRKILERILRPKEENAVKKSGFKLWSSHLNNPHKTYMRLEELQRRIMEEVHVEGIKKNDKLFNEINQWHFQNE-------NTSTVRTPTLLIHGYAASSMSFFRNYPGLSKHIRNLYSIDMPASGLSSVPSLEINTTTPLPLDIKFIGENKFKVPYTINANHNKFVIQMYEDFYLDRIEQWRIDNKLGKMNVVGHSFGGYLSFKYAVKYPNSVNKLCLVSPLGVERNIWSVNNNFHSNTLYTIDFKNPNSKFYSKRNMIPKYLFEQQFHILRMMGPLGAKLCWNYIMAAYSRVPSLAYKEYIFELFYGKGGIPEVTTDIFKALFSRCILAKDPLMDSLQYLN-VKKLLIVYGQYDWMNKKAGMFMVKELNNLKNCLEGASYLEIPSSGHNLFLDNPESFNQSIVSFLSDETKSP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . * . .: *:. : ::: : . : * * . :** :::**:... : * *. * ::::*: . * ** * : :. *: :: ** ** : * ::**.:**:*: *:::**. *.:* **.* *. : : : : : . : : :* ** * * . : .: .: : : :* . ** : *: *::: : : : :::* :: .:* : . . * .:.* :: *:*. ** : .: ", "identical_positions": 54, "similar_positions": 101, "identity": "11.71%" }, { "cls_id": "homologset.agr.SGD:S000002533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VBM6-1", "uniprot_id": "Q9VBM6_DROME", "id": "Q9VBM6-1", "name": "Palmitoyltransferase", "aln": "---------------------------MC-----IVNDWCREYANLYPKKAVSIG----HPLSVIFLLVSTVFFFTLQVFYVAPDVHD--GFMYKFFVISAIFTTYNILGNLLACYRTSSAVKSLPQERQIPKPGTEHLWHY----------CDICQKLMPPRSWHCALCKCCILKRDHHCIFAATCIGHNNHRYFFWLTFYLAFGIFMSMAT---LFVDVGRSFYLLHRMKAGFGNTVKSLSY------FRYVCLI-LNIFALGFPALMLRFQVQILKL---NSTYYQISSRHHDLGFRNNCQLIMGQRGLWTFISPSLRSPLPHDGTHWKIKQCF----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM5-1", "uniprot_id": "Q9VBM5_DROME", "id": "Q9VBM5-1", "name": "Palmitoyltransferase", "aln": "---------------------------MC-----YVNRFCHYFANRYPKNFVRIV----HPLSIVFVLCSTAFFFSLQMFYIAPKVFG--DIAYKLYWILVTFITHNILGNMLACYMTSSSVNTLSKDSRCPNPEDEPLWHY----------CESCKKLRSPRSWHCVLCNTCILRRDHHCIFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFCMFILQNGGNFMSLSSVIFNLITRTFFQNYT--GNTFETIAFL-LNISASYMPAFMLAYQMQILSQ---NSTYYNIFDCTYDLGFRKNCQTIMGQRGLWTFISPLLKSPLPHDGAHWQMKQSH----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM7-1", "uniprot_id": "Q9VBM7_DROME", "id": "Q9VBM7-1", "name": "Palmitoyltransferase", "aln": "---------------------------MC-----LIWACTKYLARRNPKIFVRIS----HPTAVLFVIVTTIFFVVLQMFYVVPQLFDVQGFMYKLGWLVAIFITYNIFGNMLACHITSTSVESLPKDRQIPEPEEEHQWHY----------CDVCEKLMPPRSWHCILCKCCILKRDRHCIFTASCVGHNNQRYFFWFTLFMALGTGVALAT----HIIATLKYFSYSDLIFLNIPRDNLPPF------WLVITLI-LNTYVFAAPVSSVLMQLSVLKN---NGTLHKFYSDTYDLGLWENFKLILGGKGFWTFLSPTVKSPLPHDGAQWKIKRVQHHSPKLQFLRVSD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQN9-1", "uniprot_id": "Q8IQN9_DROME", "id": "Q8IQN9-1", "name": "Palmitoyltransferase", "aln": "---------------------------MC-----FMMIGCKYIANANPKRFAKIV----HPSAVGFVLVGTVLFFSVEMFYMLPRIYDTDGLFFKIAWLMALFIVYNLLGNMLACHRNSSAVTSLPKDRQIPCPEEKHLWHF----------CDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLATHVNLLIIDEQIRRQYVVLHFSRFFLFLKPMSC--ELIALNISFI-INIYACILSLIMLGYQIPALYL---NTTFYTPKDYRYNQGLLGNFMAFMGKRGLWTFISPSIRSPLPHDGTKWQTKQAPTTF-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM8-1", "uniprot_id": "Q9VBM8_DROME", "id": "Q9VBM8-1", "name": "Palmitoyltransferase", "aln": "-----------------MKISHVFVQLRG-----IMQSQVQMQTINIPRRVGAIKS-WTDIMGVSINVCIILFFYFFEAFYVMPQFLG--LFGQAVHFLVTTWIVYNILENLRLCVTTLNTVDSLPPQMQQPMKGEEHLWHF----------CKICQRNVPPRSWHCNICDACILKRDHHCNFVGNCVGHNNQRYFIWFSFYAAIGSAVALFDNFMLAHKHGVGFFDLVKANYIIFNAYMNPGRKELVIFYRIVSVLGVNIFAVLFPAALFCTQVVTVIK---NSVMHDYSDRTYDLGLGNNLTLILGSRRLWTCLSPNIKSPLPHNGTRWKSKRAV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM4-1", "uniprot_id": "Q9VBM4_DROME", "id": "Q9VBM4-1", "name": "Palmitoyltransferase", "aln": "-----------------MLRFRVLLRSTCGWSRRMCFRAEEGFHRHFQLHRIKVMG-LLHPFCAIFLLCLIGLLFVYELCYVLPQITDPHGIWHKLCWFMGIYTVINILGNWWLGCMTNTSVDSLVLERQYPVAGEAHLWHY----------CSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGSGQALVYN-GILNWTNKAFLVVDPLLLMFQDTTQDADFK---WKYTIANLFKLNLFLFGVPLFMFVFQMIMVYR---NSTCYKMLDRSYDVGWRRNFDMVLGKRRFWIFFSPTISSPLPTDGTQWFQKQTV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W251-1", "uniprot_id": "Q9W251_DROME", "id": "Q9W251-1", "name": "Palmitoyltransferase", "aln": "---------------------------------------MRIRSNPMPSRMVDIL-------CFLIIAVFLPVVFMFEIVVVLPAFHEPGGFFHTFTFLMAMFLVFNIKGNMIACMMIDTSVN----VKKVEPPSDQLNWRE----------CGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKLACPMLHLVTG-SFWTNMYLVFYSLNILALAYGVLLLAYHVPIVLRGGVSADRTKESKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDLPEDGYHWNVPTNKQD--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9D6H5-1", "uniprot_id": "ZDHC4_MOUSE", "id": "Q9D6H5-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFLFYLAFLLICVVLICIFTKSQR--LKAVVLGGAQVCSRVIPQCLQRAVQTLLHQLFHTRHPTFIVLHLLLQGLVYAEYTCEVFGYCRELEFSLPYLLLPYVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSRCPTCDLRKPARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLTASAATIATVTAAFLLRLVTVSDLYQETYLDDVGHFQAVDTV---FLIQHLFLAFPRIVFLLGFVIVLSMLLAGYLCFALYLAATNQTTNEWYKGDWAWCQRW-PLVAWSPSAEPRIHQNIHSHGFRSNLREIFLPATPSYKKKEK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVR1-1", "uniprot_id": "ZDHC4_RAT", "id": "Q5FVR1-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFSFYLAFLLICVIMICIFTKSQR--LKAVVLGGAQVCARVTPQCFQRAVQTLLHQLFHTRHPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITKTNVLLLLQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLLTLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTG---FLIQHLFLAFPRIIFLLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHW-PLVAWSPSAEPQIHQNIYSHGLWSNLQEVFIPATPSYKKKKR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPG8-1", "uniprot_id": "ZDHC4_HUMAN", "id": "Q9NPG8-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFLFYLASVLMGLVLICVCSKTHS--LKGLARGGAQIFSCIIPECLQRAVHGLLHYLFHTRNHTFIVLHLVLQGMVYTEYTWEVFGYCQELELSLHYLLLPYLLLGVNLFFFTLTCGTNPGIITKANELLFLHVYEFDEVMFPKNVRCSTCDLRKPARSKHCSVCNWCVHRFDHHCVWVNNCIGAWNIRYFLIYVLTLTASAATVAIVSTTFLVHLVVMSDLYQETYIDDLGHLHVMDTV---FLIQYLFLTFPRIVFMLGFVVVLSFLLGGYLLFVLYLAATNQTTNEWYRGDWAWCQRC-PLVAWPPSAEPQVHRNIHSHGLRSNLQEIFLPAFPCHERKKQE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAM1-1", "uniprot_id": "ZDHC4_DANRE", "id": "F1QAM1-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLTLFGIYVAVVLTCIALVCKYSGHQQTPLGQLVGAFTRIVSPCIPQWLQSICYRTMHRLFHQRNNFFLYLHLLLEVVVYGEFTYEVFGFCLDMGSSSLSLCVPYILLALKSCLFYLCCSRDPGTLTKSNLSAHLKIYQYDEKLFQQGMKCSTCQLIKPARSKHCRVCNRCVQRFDHHCVWVNNCIGAQNTRYFMLYLLSVCAMAGNIAVLTTDMLLQTVLRTGLLHAHYIDEQGIQQPAGPL---FIIQHLFLTFPRIVFMLGFLVFVFFLLAGYCLFHFYLVLVNQTSNEWFKAKGHNCQHCHPYSGHNCRTSYNPFRGFYHRGILKNIGEIFWPLRPVQKKEN-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04629-1", "uniprot_id": "SWF1_YEAST", "id": "Q04629-1", "name": "Palmitoyltransferase SWF1", "aln": "----------MSWNLLFVLLIGFVVLILLSPVFKSTWPFSTFYRNVFQPFLVDDQKYRWKLHLVPLFYTSIYLYLVYTYHMRVESTIKNELFLLERILIVPIIILPPVALGILAMVSRAEDSKDHKSGSTEEYPYDYLLYYP-------AIKCSTCRIVKPARSKHCSICNRCVLVADHHCIWINNCIGKGNYLQFYLFLISNIFSMCYAFLRLWYISLNSTSTLPRAVLTLTILCGCFTIICAIFTYLQLAIVKEGMTTNEQDKWYTIQEYMREGKLVRSLDDDCPSWFFKCTEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTDLI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * * ..** ** *. *: *:** : *:* * * . : ", "identical_positions": 15, "similar_positions": 12, "identity": "4.25%" }, { "cls_id": "homologset.agr.SGD:S000002535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0M0-1", "uniprot_id": "WDR59_MOUSE", "id": "Q8C0M0-1", "name": "GATOR2 complex protein WDR59", "aln": "------------------------MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWK-DGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAG--ASQVKWNKKNANYLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWDYRQPRK-YLNILPCQVPVWKARYTPFSNGLVTVMVPQLRR-ENSLLLWNASDLN-------APVHTFVGHDDVVLEFQWRRQKEGS-----KDYQLVTWSRDQTLRMWRVDYQMQRLCANDILDGVDEFIESISLL--PEPEKTPHPQDIDHQPSLSHGEED-------AIKEDPPSSLLEEKRSDQLG------LPQTLQQEFSLINVQIRNVNVE-MDAADRSCTVSVHCSNHR--------VKMLVTFPAQYPN-NAAPSFQFINPTTITSAVKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSCLESFVNQEDS---------ASSNPFALQNSVTPPLPTFARVTTAYG-------------------------SYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLYSGSPTRSEKE-----------QVSISSFYYKER-------------------KSRRWKSKR---------------EGSDSGNRPIKAAGKVIIQDVSCLLPVHKSLGELYILNVNDTQETCQKNATSAMLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWARHPFGRQLLESLWGDRESTRVCGPPLSGARLAHYCQLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHSRYPS---------FTSSGSCSSMSDPGFNTGGWN---IAGRETEHISSP--WGESSPEELRFGSLTYSDPRERE---------------------------RDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPD-------PHKGIEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G9F8-1", "uniprot_id": "A0A8I6G9F8_RAT", "id": "A0A8I6G9F8-1", "name": "GATOR2 complex protein WDR59", "aln": "------------------------MAARWSSENVVVEFRDSQATAMSVDCVGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWK-DGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPAVALSAVAG--ASQVKWNKKNANYLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWDYRQPRK-YLNILPCQVPVWKARYTPFSNGLVTVMVPQLRR-ENSLLLWNVFDLN-------TPVHTFVGHDDVVLEFQWRRQKEGS-----KDYQLVTWSRDQTLRMWRVDYQMQRLCANDILDGVDEFIESISLL--PEPEKTLHPQDTDHQPSLSHGEEDGNVTDVLAIKEDPPSSLLEERRSDQLG------LPQTLQQEFSLINVQIRNVNVE-MDAADRSCTVSVHCSNHR--------VKMLVTFPAQYPN-NAAPSFQFINPTTITSAVKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSCLESFVNQEDS---------ASSNPFALPNSVTPPLPTFARVTTAYG-------------------------SYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLYSGSPTRSEKE-----------QVSISSFYYKERMSPRSARRRWSIQAINDFPKSRRWKSKR---------------EGSDSGNRPIKAAGKVIIQDVSCLLPVHKSLGELYILNVNDTQETCQKNATSAMLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWARHPFGRQLLESL------------------LAHYCRLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNFVVSHSRYPS---------FTSSGSCSSMSDPGFNTGGWSIVSLAGRETEHISSP--WGESSPEELRFGSLTYSDPRERE---------------------------RDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPD-------PHKGIEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PJI9-1", "uniprot_id": "WDR59_HUMAN", "id": "Q6PJI9-1", "name": "GATOR2 complex protein WDR59", "aln": "------------------------MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWK-DGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAG--ASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRK-YLNILPCQVPVWKARYTPFSNGLVTVMVPQLRR-ENSLLLWNVFDLN-------TPVHTFVGHDDVVLEFQWRKQKEGS-----KDYQLVTWSRDQTLRMWRVDSQMQRLCANDILDGVDEFIESISLL--PEPEKTLHTEDTDHQHTASHGEEE-------ALKEDPPRNLLEERKSDQLG------LPQTLQQEFSLINVQIRNVNVE-MDAADRSCTVSVHCSNHR--------VKMLVKFPAQYPN-NAAPSFQFINPTTITSTMKAKLLKILKDTALQKVKRGQSCLEPCLRQLVSCLESFVNQEDS---------ASSNPFALPNSVTPPLPTFARVTTAYG-------------------------SYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLYSGSPTRSEKE-----------QVSISSFYYKER-------------------KSRRWKSKR---------------EGSDSGNRQIKAAGKVIIQDIACLLPVHKSLGELYILNVNDIQETCQKNAASALLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWARHPFGRQLLESL------------------LAHYCRLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHSRYPS---------FTSSGSCSSMSDPGLNTGGWN---IAGREAEHLSSP--WGESSPEELRFGSLTYSDPRERE---------------------------RDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPD-------PHKGIEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKK2-1", "uniprot_id": "WDR59_DROME", "id": "Q9VKK2-1", "name": "GATOR2 complex protein Wdr59", "aln": "MPPTETLRPGERGTAGGPGAGAPEQTYIVRQSNKYYEHRDSQATAMSVDYSGQWVLLAGRGHLALQRLGQDDGSLRRHERQSKYEVSVAEFAICPSRKEYCAIATSQHIDIVRWG-TAEPHYEMSLRGHTRTVTDIDWHGKDPNLLVSCSIDTFSHIWDLREPRKPALSLNAVCMSGATQVGFNRVSGNLLAAAHDGDLRIWDIRKGSCPTHYITAHLNRVHGINWSHKRETCLATASQDGTVKYFDVCNPRR-AEKIITTMSPVWRARYTPIGNGLVSIVVPHLGRGENSLLLWSNSKQT-------DPICSFVGHTDVILDFAWRPNRESS-----NEIELVTWSRDRTLRVWKIDDNMLKLCEPSAEEIESRFEPDLSELRVPTPPEFLHPRSILVAASLPISTGDGACNTLPMARSPSFGGGYYRREEPHIARSLTDQPTCSLHHEFSLLNTNMPHVEVDTLDAIKRYACFKICAGGHT--------VILQVTFTTSYPSPSAPPDFQLCQGTTLSSEVSGVLLKVLRCNALQRVKKSRTCLEQCLRALVAAMKKKVAAVGG---------ADRSQLLLQ--------SPRLEGALSS-------------------------TLHDACIPYPRTSGVHFNAIGMLTTFAQPVNNKRLTLRQHTALTPRTFSSINGSGLLG------------------NVMATAQ-----------REANASFYLQER-----------------------MISGK---------------PGKQRAIRQMNGSPVVHVYDTSSLLHISRRMAREFSLDKCNIAETCRKNGEICRQHGRLDLVPVWLLAELIATPQIPHETLN--DLLFYKDPFKKSLLESL------------------IMHYAISGDIQTAVLLACLFDK-------------CPTGGGAIMEKTVRLPP---------QLNSQISPYHTVLPLDVKSSSSSNTWQQLKQLRSNS--WSDS------------LDLEIKQ---------------------------IQSDAYACSLIRRTKMPLFDQFKRAYAEILFGWQLLSKRALILKHTQNTPP-------PVQGVEFVTECRKCAKPKRTPKCEPCKRPVLFCVLCRLPVKGAANACLACGHGGHIDHMMQWFEKHNVCAT-CGCKCLERTSELLALLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03897-1", "uniprot_id": "WDR59_YEAST", "id": "Q03897-1", "name": "Maintenance of telomere capping protein 5", "aln": "----------------MCSSINEGPYNSPTFGKSLSLKVDGGFNAVSINPSGRDIVLASRQGLYIIDLDDPFTPPRWLHHITPWQVADVQWSPHPAKPYWIVSTSNQKAIIWNLAKSSSNAIEFVLHGHSRAITDINFNPQHPDVLATCSVDTYVHAWDMRSPHRPFYSTSSWRS-AASQVKWNYKDPNVLASSHGNDIFVWDLRKGSTPLCSLKGHVSSVNSIDFNRFKYSEIMSSSNDGTVKFWDYSKSTTESKRTVTTNFPIWRGRYLPFGEGYCIMPMVGGNNAVYLINLCDDDDSEQNKKTKLQPIYAFKGHSDRVIDFLWRSRHTCDGDYDDREFQLVTWSKDCDLKLWPISDSIYGKVNFDRGKRLEEKLPDYDYCSYNKEPENRENVQKNEFRRLRENFVTTSGLKKNKTNHITWLSGIRMNSATSQEDLFNETKIQNLGEEVSAIGHKFPKVVFEKISVSTRELCLTLNGPWSEENPDDYIFLRISINFPLNYPNKGDPPKFTIEENSNLTMSKRQEILSNLATIGQKYTDSNLYCLEPCIRFVLGEKVSLEDIEEGQEPLLNFDIADHIDFEELSSLDSSYSDSQNPENLSSQSDIESYKEALVFPDTSNQGLDFGRNLALDTTPVPNGCGSCWTATGELFCFFANEKKPEKKQNAIIKLSQKEAGVEKHPFKIEPQVLYDKEVDSSVITAADELKARPKRYVDTLGLGGGTNGDSRTYFDDETSSDDSFDSVADDWDDILRNDIIVRTKIPILRGNFKAFSSVHSESGKTVESTKKNKNLVISKNFSSLLSDRKELALEYLFMDATPEGFARNN---ALVAEKFDLDEISHCWQILSDMLIDQSDYDPYTTIWNNHPMGIKWFIKEA-----------------IVYFERQQNLQMLAMLCCVILSARRKKIPARYYGQELENMEGTIVFNDNESQNTSFWKGSDAFSTRSRSSTVTPNFYGNHLRGKNIHGGDNSSIRSDDHHARLRTHNTLNGSSKFTEPAQKQGSRAISSSPFHSRMPDIKVELLHDDIIEAYEQEDLLHLEVSDIPKFQTYIYQYSKLLFRWGLPLERVKILKVSTDFRSSYSSQGIPPNNNKKSPYNGVLTHWIENNEFGEEKFLARNCNYCDLRVTRSSFICGNCQHVLHSSCARIWWEIGDECPSGCGCNCPEMFDA------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. .*:*:: *: :*:.* * : *. * : : :::. .:: : : . ::.*: : . .. *:**:*.::*::: .*::*.:.*:**: : **::..::* : .: *:** :* . * **::*..*: :** ** * . : .*:. ::.::: : ::*:*.:**::* :. . :. *:*:.** *:.:* : : . : * . . *: :* ** * :::* ** .: . .: :*****:* *::* :. .: . . .. . . : . . . . . . . .* .*.* :. :: :* .: :.. * ..: : : :.*. .**. . .*.* : : :.:: :*. * . : .. . *** *:* ::. . . *. : . . * *. .* : . * * * . . . : : : . : * .:. : . . : * : :.** : :. : : .::* . : ** : : : : . : ..*: . : . : :: ::* .:*..:: : . . .: . : . . . : :: . : :. *: : *.::*: * * :*. :** * :. : . : * . * * : * :: * * * * . *:. : *.: ***:* ", "identical_positions": 123, "similar_positions": 281, "identity": "10.33%" }, { "cls_id": "homologset.agr.SGD:S000002536", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61233-1", "uniprot_id": "PLSL_MOUSE", "id": "Q61233-1", "name": "Plastin-2", "aln": "---------------------------------------MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGKISFDEFIKVFHGLKSTEVAKTFRKAINKKEGICAIGGTS-----------------EQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCT-KITNFSTDIKDSKAYYHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIK-VPVDWN-RVNKPPYPKLGGN-MKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIG-GGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKG----MKRV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13796-1", "uniprot_id": "PLSL_HUMAN", "id": "P13796-1", "name": "Plastin-2", "aln": "---------------------------------------MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTS-----------------EQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCN-KIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIK-VPVDWN-RVNKPPYPKLGGN-MKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIG-GGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKG----MKRV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P698-1", "uniprot_id": "PLSL_DANRE", "id": "Q6P698-1", "name": "Plastin-2", "aln": "---------------------------------------MAAAQISAEEMEELREAFTKVDVDGNGHISTDELNALFKAANLPLPGYRVREIIQEISRTMDLNQDGKITFDEFAKVVHDLKSSEVAKTFRKAINKKEGICSVAGTS-----------------EQS--GTQHSYSEEEKVAFVNWVNKALEKDPDCQHVLPMDPSTDDLFTAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIEISRNEALIALLRDGESLEDLVKLSPEELLLRWANYHLEEAGCP-KINNFSSDIKDSKAYYNILNQVAPKRDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVVRGNPKLNLAYVANLFNKYPALK---KPENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADALVIFQLYEKIK-VPVDWD-KVNKPPYPKLGSN-MKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLG-DGQKIIDETIVQWVNETLTQAGKG-TISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARG----MRRI-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99K51-1", "uniprot_id": "PLST_MOUSE", "id": "Q99K51-1", "name": "Plastin-3", "aln": "------------------------------------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTS-----------------ELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINK----KKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQ-KINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALT---KPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIK-VPVDWS-KVNKPPYPKLGAN-MKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLG-EGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRG----MKRV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13797-1", "uniprot_id": "PLST_HUMAN", "id": "P13797-1", "name": "Plastin-3", "aln": "------------------------------------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTS-----------------ELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINK----KKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQ-KINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALT---KPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIK-VPVDWS-KVNKPPYPKLGAN-MKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLG-DGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRG----MKRV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63598-1", "uniprot_id": "PLST_RAT", "id": "Q63598-1", "name": "Plastin-3", "aln": "------------------------------------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTS-----------------ELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINK----KKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQ-KINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALT---KPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYVDLQDALVILQLYERIK-VPVDWS-KVNKPPYPKLGAN-MKKLENCNYAVELGKNQAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVMEDLG-EGQKATDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKTGNLTEEDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRG----MKSV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DG81-1", "uniprot_id": "PLST_DANRE", "id": "Q6DG81-1", "name": "Plastin-3", "aln": "---------------------------------------MAG-KISKEELEELREAFGKVDLNGNGFICDHELHDLFKEANLPLPGYKVREIIQKLMEEGDKNKDNMISFDEFVSIFQELKSGDIAKSFRKAINRKEGILAIGGTS-----------------ELSSAGTQHSFSEEERFAFVNWINTALEHDPDCKHKLPMNPNTDALFKAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGALDLREGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEDLMKLSPEELLLRWANFHLENAGWS-KINNFSHDIKDSRAYFHLLNQIAPKGQKDGESRIDIDMSGFTEKDDLKRAECMLLQADKLGCRQFVTSTDVMSGNPKLNLAFVANLFNKYPALT---KPENQDINWGLLEGETREERTFRNWMNSLGVNPHVNHLYGDLQDALVILQLYEKIK-VPVDWNNKVNKPPYPKLGAN-MKKLENCNYAVELGKTKANFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLENLG-DGQKVNDDVIVSWVNKTLSQAGKSTKISNFKDKEISSSLAVLDLIDAIQPSSINYDLVKRGSLSDGDKLDNAKYAVSMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRG----MKRA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3V0K9-1", "uniprot_id": "PLSI_MOUSE", "id": "Q3V0K9-1", "name": "Plastin-1", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILVVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTS-----------------SISSEGTQHSYSEEEKVAFVNWINKALENDADCSHLLPMNPNDGSLFKSLADGILLCKMINLSEPDTIDERAINK----KKLTPFTVSENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKDGEDLEELMKLSPEELLLRWVNYHLTNAGWR-TINNFSQDIKDSKAYFHLLNQIAPKGDRDDGPAVAIDLSGFNEKNDLKRAGFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPCLH---KPDNNDIDLNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWS-QVNKPPYPALGGN-MKKIENCNYAVELGKNEAKFSLVGIAGQDLNEGNATLTLALVWQLMRRYTLKVLSDLG-EGEKVTDDIIIKWVNQTLKSANKSTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIKREHLTDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKG----LNRLK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXW3-1", "uniprot_id": "A0ABK0LXW3_RAT", "id": "A0ABK0LXW3-1", "name": "", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILVVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTS-----------------SISSEGTQHSYSEEEKVAFVNWINKALENDADCSHLLPMNPNDGSLFRSLADGILLCKMINLSEPDTIDERAINK----KKLTPFTVSENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEELEELMKLSPEELLLRWVNYHLTNAGWR-TISNFSQDIKDSKAYFHLLNQIAPKGDRDGGSAVTIDLSGFNEKNDLKRAGFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPCLH---KPDNNDIDLNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWN-HVNKPPYPALGGN-MKKIENCNYAVELGKNEAKFSLVGIAGQDLNEGNATLTLALVWQLMRRYTLKVLSDLG-EGEKVSDDIIIKWVNQTLKSANKSTSISSFKDKSISTSLPVLDLIDAIAPNAVRPEMIKREHLTDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKG----LNRLK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14651-1", "uniprot_id": "PLSI_HUMAN", "id": "Q14651-1", "name": "Plastin-1", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTS-----------------TISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINK----KKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWH-TISNFSQDIKDSRAYFHLLNQIAPKGGED-GPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLH---KPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWS-HVNKPPYPALGGN-MKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLG-EGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKG----LNRIK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QBL9-1", "uniprot_id": "A0A8M9QBL9_DANRE", "id": "A0A8M9QBL9-1", "name": "", "aln": "MALITRGLHRIFLWTKRQNSTITGPFLHGVKCFEETSMENKVTQISREDLEDLREAFNKIDIDNSGYVSDFELQELFREASFHLPGYQIREIVEKFIAG-DTNKDEKISFEEFVAISQELRSKEVRETFRKCISRRDGIRSFGGTS-----------------GISSEGTQHSYSDEEKVAFVNWVNKALANDPDCKHLIPMDPGTDSLFKSVKDGILLCKMINLSQPDTIDERVIN-----KKCTPFTMTENLMLALNSASAIGCTVVNIDAQDMKAGTPHLVLGLLWQIIKIGLFADIEISRNEALIALLDESEELDHLMSMSPEDLLLRWVNYHLKAAGWK-QIRNFSEDIKDSRAYFHLLNQISPKGDLDDQMRIDIDMLGLTERDDEMRAELMLRQAARLDCRQFVTPKDVVAGNHKLNMAFVANLFNMYPALN---RPTDNGIDY-AIEGETREDRTFRNWMNSLGVSPYVNHLYSDLHDGLIILQLYERIQ-IPVDWP-RVNKPPYPVLGSN-MKKLENCNYAVALGKKEAKFSLVGIGGENINEGSPMHTLALVWQLMRRYTLKVLSDLG-DGEKVSDQIIINWVNSTLKQGDKNSSISSFKDKSISTSLPVIDLIDTIVPKAIKYEMVKSGDMTAEDKLNNAKYAISVARKIGVKVYALPDDLVEVKPKMVMTVFACLMGRG----LKKVDG-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQZ7-1", "uniprot_id": "Q8IQZ7_DROME", "id": "Q8IQZ7-1", "name": "", "aln": "---------------------------------MADILNVEQHQTVQEFKQNLEELIPNLDANKDGFIDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKLNLEEFEALCLDLKSKDVASTFKTVVSKKENLETLGGMS-----------------SISSEGTTHSVRLEEQLAFSDWINSNLGHDKDLQHLLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAINK----KNLTVYREFENLTLALVSSQAIGCNIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKMSPEAILLRWVNHHLERAGISRRCTNFQSDIVDSEIYSHLLKQIAGN-------DADVNLDALRESDLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLD---KPEQ--IEGLESIEETREEKTYRNWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWS-RVHKR-FSPLRKF-MEKLENCNYAVDLG-KQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSG-TQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMMALDYVPNMDSVDQNNHNSSANNSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32599-1", "uniprot_id": "FIMB_YEAST", "id": "P32599-1", "name": "Fimbrin", "aln": "--------------------------------MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEAVSKD-----GDATYDEARETLKHVGVDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNSTPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIGDLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPA---------LCSKAPLQTTDLMERAEQVLQNAEKLDCRKYLTPSSLVAGNPKLNLAFVAHLFNTHPGLEPIQEEEKPEIEEFDAEGE-REARVFTLWLNSLDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFK-HVNKRPASGAEISRFKALENTNYAVDLG-RAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGN-TEEERYANARLAISIARKLGALIWLVPEDINEVRARLIITFIASLMTLN-----K---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :* : .* : : . * : : . : :::: : ::. . : :. .. . .. . : * ** *: **: * . :*. * * * . :*: . *: **::*.*:** * ***** *.:* *: . : ** :.: *:.**** :**: : *: * :*:***:**:*: **::.* :. * ** :.* *:.:: :.** :**** *.** :. **. *: *.. * :*:*: . : : ** :* :* :*.*:.::*. .:: * ***:*::*:*** :* * . . *: * :* :.: *:**:.* * : *: ** *.*:::* :: : *:: :*:* . :: :** **** ** ****** *.:: :*. **.::***** :. :. *. :. *:.*.: : .. * : .*:* :: . ::*::: * : ::: .. **: *:*:**::*. :: :*:*: **..::::*.:*.:* . ", "identical_positions": 154, "similar_positions": 197, "identity": "21.63%" }, { "cls_id": "homologset.agr.SGD:S000002542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88563-1", "uniprot_id": "MRP3_RAT", "id": "O88563-1", "name": "ATP-binding cassette sub-family C member 3", "aln": "---------MDRLCGSGELGSKFWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHRLGYIVLSCLSRLKTALGVLLWCISWVDLFYSFHGLVHGS--SPAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDP------------FRFTTFYIYFALVLCAFILSCFQEKPPL----FSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIA-----------------GEDEVLLK-ARPKTK--------KPSFLRALVRTFTSSLLMGACFKLIQDLS-PSSTHSCSASSSGLFRP--------------------HGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQ-GELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTIS---PGRAITIHN-GTFSWSK--DLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGS-FANFLRNYAPDENQ---EANEGVLQHAN-EEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKET--GALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTND-VEEHGQQN---NTSVRLGVYATLGILQGLLVM-LSAFTMVVGAIQAARLLHTALLHNQIR-APQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGR--NSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESNR-APEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQP-TGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAA-GGIFYGMAKDAGLA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RX12-1", "uniprot_id": "MRP3_MOUSE", "id": "B2RX12-1", "name": "ATP-binding cassette sub-family C member 3", "aln": "---------MDRLCGSGELGSKFWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHQLGYIVLSWLSRLKTALGVLLWCVSWVDLFYSFHGLIHGS--SPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDP------------FRFTTFYIYFALVFCALILSCFKEKPPL----FSPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRSQTATAEPKIP-----------------GEDAVLLK-PRPKSK--------QPSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDP--------------------TAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQ-SELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTIS---PGYAITIHN-GTFTWAQ--DLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGS-FANFLRNYAPDEDQ---EDHEAALQNAN-EEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKET--GALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSND-AEEHGQQN---KTSVRLGVYAALGILQGLLVM-LSAFTMVVGAIQAARLLHEALLHNKIR-SPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGR--NSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNR-APEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQP-AGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAA-GGIFYGMAKDAGLA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15438-1", "uniprot_id": "MRP3_HUMAN", "id": "O15438-1", "name": "ATP-binding cassette sub-family C member 3", "aln": "---------MDALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGR--APAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDP------------FRFTTFYIHFALVLSALILACFREKPPF----FSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNAS----------------GEDEVLLG-ARPRPR--------KPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNP--------------------MAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQ-GELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTIS---PGYAITIHS-GTFTWAQ--DLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGS-FANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEK-VQVTEAKAD--GALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTND-AMADSRQN---NTSLRLGVYAALGILQGFLVM-LAAMAMAAGGIQAARVLHQALLHNKIR-SPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGR--SSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSR-PPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQP-AGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAA-RGIFYGMARDAGLA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXY3-1", "uniprot_id": "A0A8M3AXY3_DANRE", "id": "A0A8M3AXY3-1", "name": "", "aln": "---------MEHLCGPDKP---FWELNLTLYGQQPDLPECFQMSVLSWAPCIYLWAAAPLYILHLRRNNRGYIMMSILNRIKTVLGLILWIVCWTDLFSAFHQMNQGS--KISPIYFVTPLIVGMTMLLATFLIQFERLKGVQSSGVLFIFWTLSVVFAIVPFRSKIMHANTE-QVKDK------------LRFTTFYIYFSFTLLELILSCFNEKPPL----FSSAVMDPNVCPETTAGFLSRMTFWWFTRMAIKGYKSPLENKDLWSLNKNDSSELVVPGLLNQWEVEKSKAHSSDDQNVKEQVTFTKPGSGAESNHVNESPEEAEVLLSKQQQKSR--------QPSFLWALLRAFGPYFLIGSAFKLLQDLITFINPQLLRMLIAFTKQS--------------------DVPSWWGYALAFLMFGTSLLQTLILHQHFQYCFVTGMRLRTGIIGAIYRKALVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIFLALFFLWQNLGPSVLAGVAVMVLLIPFNAFIAMKTRTYQVEQMKYKDDRIKLMNEILNGIKVLKLYAWEPSFRDKILQIRQ-KELHVLRKTAYLSALSTMAWTSAPFLVALTSFAVFVNVDEKNVLDAEKAFVSLSLFNILRFPLNMLPQVISSIVQASVSLKRLQDFLNHDELDPESVDRKSNT---TEYAVSVVN-GKFSWAK--RDQVILDNINVLVPQGSLLAVVGHVGCGKTSLISALLGEMEKLDGQISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLLDDPLSAVDAHVAKHIFDHVIGPEGALKGKTRILVTHGISFLPQVNNILVLVDGRVSEMGSYQDLLRQNGA-FAEFLRNYSLEDII---EDDELTVSFDE-EEEEFPEDALSNHTDMVDNEPVVNEARRQFMRQMSIMSNDVENPKKMSRRRRCSERKHPETPTEKKEPKVEKLIQAETTETGRVKLQVYWEYVKAIGPLLALFICFLYGCQSAAAIGANFWLSEWTND-ALHNRTQE---MLQTRVGVYAALGISQGVLILSICLLCRAYSTLRAARHTHQHMLNSVLR-APQAFFEATPSGRVLNRFSKDVDTIDSLIPDNIDIWMRTFWYTVNVLMVCSVLTPIFLIVIVPLMLFYWWVQRFYVATSRQLKRLESVSRSPIYSHFSESITGTSVIRAYGRNAAFVLMSDNKVDENQKSYYPGIVSNRWLGVRIEFIGNCIVLFAALFAVTGK--DKLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETQTEAPWEVLEKK-PPPDWPPLGNVEFVDYSVRYREGLDLVLKNISLKVRGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEIVIDDVKISEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFERYSDEEVWKALELSHLQKFVTNQA-AKLELECSEGGENLSVGQRQLVCLARALLRKTRILVLDEATAAVDLETDDLIQSTIRTEFQDCTVFTIAHRLNTIMDYTRVLVLDKGQIAEFDTPTNLMNQ-KGLFFGMAKDAGLA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35379-1", "uniprot_id": "MRP1_MOUSE", "id": "O35379-1", "name": "Multidrug resistance-associated protein 1", "aln": "-------MALRSFCSADGSDP-LWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFFYLSRHDRGYIQMTHLNKTKTALGFFLWIICWADLFYSFWERSQGV--LRAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAHVDV------------FRDSTFYLYFTLVLVQLVLSCFSDCSPL----FSETVHDRNPCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQLDVN---EEVEALIVKSPHKDR--------EPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDR--------------------EAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQ-EELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEG-NSITVKN-ATFTWAR--GEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGA-FAEFLRTYANAEQD----------LASEDDS---VSGSGKESKPVENGMLVTDTVGKHLQRHLSNSSS----HSGDTSQQHSSIAELQKAGAK-EET--WKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTDDPPVVNGTQA---NRNFRLSVYGALGILQGAAIF-GYSMAVSIGGIFASRRLHLDLLYNVLR-SPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISR--HSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETA-PPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALP-DKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQ-RGIFYSMAKDAGLV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CG09-1", "uniprot_id": "MRP1_RAT", "id": "Q8CG09-1", "name": "Multidrug resistance-associated protein 1", "aln": "-------MALSSFCSSDGSDP-LWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFLYLSRHDRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGM--LLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDM------------FRDSAFYLYFTLVFIQLVLSCFSDSSPL----FSETVRDPNPCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVN---EEVEALIVKSSHKDR--------DPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDR--------------------EAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQ-EELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKN-ATFTWAR--DEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGA-FAEFVRTYANTEQD----------LASEDDSKNGVSGLGKESKPVENGILVTDAVGKPLQRHLSNSSS----HSVVTNQQHSSTAELQKSGVK-EET--WKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQE---NRNFRLSVYGALGILQGVAVF-GYSMAVSIGGIFASRRLHLDLLQNVLR-SPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISR--HSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQETA-PPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALP-DKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQ-RGVFYSMAKDAGLV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33527-1", "uniprot_id": "MRP1_HUMAN", "id": "P33527-1", "name": "Multidrug resistance-associated protein 1", "aln": "-------MALRGFCSADGSDP-LWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGI--FLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDL------------FRDITFYVYFSLLLIQLVLSCFSDRSPL----FSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSS-KDPAQPKESSKVDAN---EEVEALIVKSPQKEW--------NPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDT--------------------KAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQ-EELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRN-ATFTWAR--SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGA-FAEFLRTYASTEQE----------QDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSS----YSGDISRHHNSTAELQKAEAKKEET--WKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDD-PIVNGTQE---HTKVRLSVYGALGISQGIAVF-GYSMAVSIGGILASRCLHVDLLHSILR-SPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISR--HSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETA-PPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALP-DKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYSMAKDAGLV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTC0-1", "uniprot_id": "Q7KTC0_DROME", "id": "Q7KTC0-1", "name": "ABC-type glutathione-S-conjugate transporter", "aln": "-MADDTSSPMDRFCG-----STFWNATETWYTNDPDFTPCFEQTALVWTPCAFYWAFVIFDFYYLKASLDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELPLYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPR----QTKYQRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKARVEPKAQFSNGN------------VTFENPHGEKNGRKKG--------MASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQD-------------------AEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRD-KEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSK----PHPMSIEN-GEFSWG----DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGA-FADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGG---SLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTG----LRDMYLGVYGAFGFGQGVLAY-FAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLG---GQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLA-AGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANLV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8VI47-1", "uniprot_id": "MRP2_MOUSE", "id": "Q8VI47-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "---------MDEFCN-----STFWNLSLLKSPE-ADLPLCFEQTVLVWIPLGFLWLLAPWQLYRIYRSRTKRFAITKFYLAKQVFVVCLLILAAIDLSLALTEDTGQA--TIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMT-------------YSCLFFVSYGFQIVILILSAFSESS------------DSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKS-QQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDP--------------------DSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRK-KELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHF----DKAVQFSE-ASFTWDR--DLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGV-FAKNWKTFMKHSGP-----EGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLL-SSSLWSIYACRNASKTLHRQLLTNILR-APMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYK--NSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKP--PADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQ-LGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSN-MGPFYLMAKEAGIESVNHTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63120-1", "uniprot_id": "MRP2_RAT", "id": "Q63120-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "---------MDKFCN-----STFWDLSLLESPE-ADLPLCFEQTVLVWIPLGFLWLLAPWQLYSVYRSRTKRSSITKFYLAKQVFVVFLLILAAIDLSLALTEDTGQA--TVPPVRYTNPILYLCTWLLVLAVQHSRQWCVRKNSWFLSLFWILSVLCGVFQFQTLIRALLKDSKSNMA-------------YSYLFFVSYGFQIVLLILTAFSGPS------------DSTQTPSVTASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSKFEAAMTKDLQKARQAFQRRLQKS-QRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEK--TTKDYPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIGFVKSS--------------------NSYVWFGYICAILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRK-KELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRVSNF----DKAVKFSE-ASFTWDP--DLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGV-FARNWKTFMKHSGP-----EGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRIGVFGALGLAQGICLL-ISTLWSIYACRNASKALHGQLLTNILR-APMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVIYR--KTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDKRP--PADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQ-LGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSN-RGSFYLMAKEAGIENVNHTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92887-1", "uniprot_id": "MRP2_HUMAN", "id": "Q92887-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "--------MLEKFCN-----STFWNSSFLDSPE-ADLPLCFEQTVLVWIPLGYLWLLAPWQLLHVYKSRTKRSSTTKLYLAKQVFVGFLLILAAIELALVLTEDSGQA--TVPAVRYTNPSLYLGTWLLVLLIQYSRQWCVQKNSWFLSLFWILSILCGTFQFQTLIRTLLQGDNSNLA-------------YSCLFFISYGFQILILIFSAFSENN------------ESSNNPSSIASFLSSITYSWYDSIILKGYKRPLTLEDVWEVDEEMKTKTLVSKFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKALFKTFYMVLLKSFLLKLVNDIFTFVSPQLLKLLISFASDR--------------------DTYLWIGYLCAILLFTAALIQSFCLQCYFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRK-KELKNLLAFSQLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRHDCNF----DKAMQFSE-ASFTWEH--DSEATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGE-FAKNLKTFLRHTGP-----EEEATVHDGSEEEDDDYGLISSVEEIPEDAASITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVKGQKLIKKEFIETGKVKFSIYLEYLQAIGLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDSKIFNSTDYPASQRDMRVGVYGALGLAQGIFVF-IAHFWSAFGFVHASNILHKQLLNNILR-APMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGNLTVFFSALMMVIYR--DTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPWVTDKRP--PPDWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQ-LGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELLQI-PGPFYFMAKEAGIENVNSTKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1S7-1", "uniprot_id": "MRP6_MOUSE", "id": "Q9R1S7-1", "name": "ATP-binding cassette sub-family C member 6", "aln": "MNRGRSMATPGEQCAG----LRVWNQTEQEPAAYHLLSLCFVRAASSWVPPMYLWVLGPIYLLYIHRHGRCYLRMSHLFKTKMVLGLALILLYTFNVAVPLWRIHQGV--PQAPELLIHPTVWLTTMSFATFLIHMERRKGVRSSGVLFGYWLLCCILPGINTVQQASAGNFRQEPLHH---------------LATYLCLSLVVAELVLSCLVDQPPF----FSEDSQPLNPCPEAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWRRSCNGLPGH--------KGHSSVG-----------APETEAFLQPERSQRG----------PLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDR--------------------NSSAWTGWLLAVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDIQRLAESIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRGFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWEHAFLERLLHIRG-QELSALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSRRSS-KDRISVHN-GTFAWSQ--ESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNGA-LVGLLDGARQPAG--------------------------THDAATSDDLGGFPGGGRPTCRPDRPRPT------EAAPVKGRSTSEVQMEASLDDPEATGLTAEEDSVRYGRVKTTIYLSYLRAVGTPLCTYTLFLFLCQQVASFSQGYWLSLWADDPVVDGRQMH----AALRGWVFGLLGCLQAIGLF-ASMAAVFLGGARASGLLFRSLLWDVAR-SPIGFFERTPVGNLLNRFSKETDTVDVDIPDKLRSLLTYAFGLLEVGLAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARYSSVCSHMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFVAATCAVLSK--AHLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWRLPTCA-AQPLWPCGGQIEFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLP-GQLQYECAGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEMQMQAALERWFTQCTVLLIAHRLRSVMDCARVLVMDEGQVAESGSPAQLLAQ-KGLFYRLAHESGLA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88269-1", "uniprot_id": "MRP6_RAT", "id": "O88269-1", "name": "ATP-binding cassette sub-family C member 6", "aln": "MNGEHSMATPGESCAG----LRVWNQTEQEPVAYHLLNLCFLRAAGSWVPPMYLWVLGPIYLLYIHRHGCCYLRMSRLFKIKMVLGFALILLYTFNAAVPLWRIHRGM--PQAPELLIHPTVWLTTMSFATFLIHMERKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHH---------------LATYLCLSLVVAELVLSCLVDQPPF----FSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRRNFSELPGH--------KGHSGMG-----------TPETEAFLQPERSQRG----------PLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDL--------------------ESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRG-QELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSS-KDRISIHN-GTFAWSQ--ESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGA-LVGLLDGARQPAGE---------------------GEGEAHAAATSDDLGGFSGGGTPTRRPERPRPS------DAAPVKG-STSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMH----SALRGSIFGLLGCLQAIGLF-ASMAAVFLGGARASCLLFRSLLWDVAR-SPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSK--AHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSA-AQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLP-GQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQ-KGLFYRLAQESGLA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95255-1", "uniprot_id": "MRP6_HUMAN", "id": "O95255-1", "name": "ATP-binding cassette sub-family C member 6", "aln": "------MAAPAEPCAG----QGVWNQTEPEPAATSLLSLCFLRTAGVWVPPMYLWVLGPIYLLFIHHHGRGYLRMSPLFKAKMVLGFALIVLCTSSVAVALWKIQQGT--PEAPEFLIHPTVWLTTMSFAVFLIHTERKKGVQSSGVLFGYWLLCFVLPATNAAQQASGAGFQSDPVRH---------------LSTYLCLSLVVAQFVLSCLADQPPF----FPEDPQQSNPCPETGAAFPSKATFWWVSGLVWRGYRRPLRPKDLWSLGRENSSEELVSRLEKEWMRNRSAARRHNKAIAFKRKGGSGMK-----------APETEPFLRQEGSQWR----------PLLKAIWQVFHSTFLLGTLSLIISDVFRFTVPKLLSLFLEFIGDP--------------------KPPAWKGYLLAVLMFLSACLQTLFEQQNMYRLKVLQMRLRSAITGLVYRKVLALSSGSRKASAVGDVVNLVSVDVQRLTESVLYLNGLWLPLVWIVVCFVYLWQLLGPSALTAIAVFLSLLPLNFFISKKRNHHQEEQMRQKDSRARLTSSILRNSKTIKFHGWEGAFLDRVLGIRG-QELGALRTSGLLFSVSLVSFQVSTFLVALVVFAVHTLVAEN-AMNAEKAFVTLTVLNILNKAQAFLPFSIHSLVQARVSFDRLVTFLCLEEVDPGVVDSSSSGSAAGKDCITIHS-ATFAWSQ--ESPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGAVAYVPQEAWVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKGA-LMCLLDQARQPGDR---------------------GEGETEPGTSTKDPRGTSAGRRPELR--RERSI------KSVPEKDRTTSEAQTEVPLDDPDRAGWPAGKDSIQYGRVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADDPAVGGQQTQ----AALRGGIFGLLGCLQAIGLF-ASMAAVLLGGARASRLLFQRLLWDVVR-SPISFFERTPIGHLLNRFSKETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSK--AHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLPTCA-AQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLP-GQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQ-KGLFYRLAQESGLV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39109-1", "uniprot_id": "YCFI_YEAST", "id": "P39109-1", "name": "Metal resistance protein YCF1", "aln": "-MAGNLVSWACKLCRS--------PEGFGPISFYGDFTQCFIDGVILNLSAIFMITFGIRDLVNLCKKKHSGIKYRRNWIIVSRMALVLLEIAFVSLASLNISKEEAEN--FTIVSQYASTMLSLFVALALHWIEYDR--SVVANTVLLFYWLFETFGNFAKLINILIRHTYEGIWYSG-----------QTGFILTLFQVITCASILLLEALPKKPLMPHQHIHQTLTRRKPNPYDSANIFSRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENELKQ-------------------------------------------KSN---------PSLSWAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDR-ALTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNYGKKNNG----------------------KSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGSIDFGDDEN----IAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWLKHWSEVNSRYGSNPN----AARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLR-APMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHR-PPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCMEAGLVNEN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** . : : : . * : . . : : : . :* . . . ::: .: . * * : * : * **. * *::.: : : . : : * :* . : .. * : :* *: : .:: : :*:* * ::. : *: ***::** *:: : :: :* . : :.: *: ** * ..: .:: ::*.* : * :*: * .* :: ..:* : :* ..** .: .:: :* *: * . . :*: : ... : : .* :::::.:* . ::* . :: ** *: :: :::: : : . . . * * : : . * * .::* **.**::::..:*.:: .: * * ***.* .*: * :: :*: * . .:.:*** *: : * : :**:*:.*****: *:***** * :::****:*:* **.:.::..*:** * * .::::.*: : *. .: * :: * : : * : : . : . : * *: . * :: . . . . **. *:. :: :* .. *: . : * : **: ** *.::* *: : :. : : : . * : *: ..* * * :. :* **:* *.: **: *:. * :*.: * : :* . :. : ::***. :* :*. :: :: * . . .*: :* :*::* *:*::* : *..:::***: :* **. ** * ::* :: *:* * :.:: :. : **:*:**********:: *:*: *:: * * **.: : :**: ** :::****:. :* *.:* *:* : ::: :* :** :* * * : : * :**:**:**:**.**:* :::*:******::* *: :* : * *:: *****.:::: :::*:*.* : * :* :*: . *: :. ::.: ", "identical_positions": 246, "similar_positions": 374, "identity": "15.11%" }, { "cls_id": "homologset.agr.SGD:S000002544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYV2-1", "uniprot_id": "A0A8I5ZYV2_RAT", "id": "A0A8I5ZYV2-1", "name": "", "aln": "-----------MIEVVAELSRGP--VFLAGEALECVVTVTNPLPP----------------------------TATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQP----------------------------------------------------------------------------------------DSQTVFLPHRGERGQC--------------------ILSTPPKILFCDLRLDPGESKSYSYS-EVLPTEGPPSFRGQSVKYV-YKLTIGCQRVNSP------------------------ITLLRVPLRVLVLTGLQD--------------------------------------------------------------------VHFPQDEAVAPSSP----FLEEDDSGKKDSWLAELAGERLMAATSCR------------------------------SLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGT----VACLQFSVSLQTEER------------------------------------VQPEYQRR-RGTGVAPSVSHVTHAR--------HQESCLHTTRTSFSLPIPLCSTP-GFCTAIVSLKWRLHFEFVTSREPGLVLLPPLEQPEPATWTGPEQ-VPVDTFSWDLPIKVLPTSPTLVSYAAPGPSTSSITI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHT7-1", "uniprot_id": "RGP1_MOUSE", "id": "Q8BHT7-1", "name": "RAB6A-GEF complex partner protein 2", "aln": "-----------MIEVVAELSRGP--VFLAGEALECVVTVTNPLPP----------------------------TATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQP----------------------------------------------------------------------------------------DSQTVFLPHRGERGQC--------------------ILSTPPKILFCDLRLDPGESKSYSYS-EVLPTEGPPSFRGQSVKYV-YKLTIGCQRVNSP------------------------ITLLRVPLRVLVLTGLQD--------------------------------------------------------------------VHFPQDEAVAPSSP----FLEEDDSGKKDSWLAELAGERLMAATSCR------------------------------SLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGT----VACLQFSVSLQTEER------------------------------------VQPEYQRR-RGTGVAPSVSHVTHAR--------HQESCLHTTRTSFSLPIPLCSTP-GFCTAIVSLKWRLHFEFVTSREPGLVLLPPLEQPEPATWTGPEQ-VPVDTFSWDLPIKVLPTSPTLVSYAAPGPSTSSITI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92546-1", "uniprot_id": "RGP1_HUMAN", "id": "Q92546-1", "name": "RAB6A-GEF complex partner protein 2", "aln": "-----------MIEVVAELSRGP--VFLAGEALECVVTVTNPLPP----------------------------TATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQP----------------------------------------------------------------------------------------DSQTVFLPHRGERGQC--------------------ILSTPPKILFCDLRLDPGESKSYSYS-EVLPIEGPPSFRGQSVKYV-YKLTIGCQRVNSP------------------------ITLLRVPLRVLVLTGLQD--------------------------------------------------------------------VRFPQDEAVAPSSP----FLEEDEGGKKDSWLAELAGERLMAATSCR------------------------------SLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGT----VACLQFSVSLQTEER------------------------------------VQPEYQRR-RGAGGVPSVSHVTHAR--------HQESCLHTTRTSFSLPIPLSSTP-GFCTAIVSLKWRLHFEFVTSREPGLVLLPPVEQPEPTTWTGPEQ-VPVDTFSWDLPIKVLPTSPTLASYAAPGPSTSTITI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DHA5-1", "uniprot_id": "A0A0C4DHA5_DROME", "id": "A0A0C4DHA5-1", "name": "RAB6A-GEF complex partner protein 2", "aln": "-----------MIEIKAKLLRADSAIYATGERVQCLIEFTHKVFSDEPA-----------------ASQAVHNANEARSQENLAWASAQLHCYRKTSYSTSAG---DRAAELTEM----------------------------------------------------------------------------------------IGRTALDAVTQAPGEV--------------------IVATKPKILFCDLRLQPGETKMYFFN-EFIPRDGPPTYRGHNIRYF-YKITIATQRVKSK------------------------VQTLAVPIRVLPIPIISRPDE---------------------------------------------------------------LPVTVETNEELAPTNP----FLE-----KREISELEISWHHLKNVTARR------------------------------APKFYRISNKRGFVGRFCLFKPAYKLGEDIVGSLDFDPGVNPRKVRCVQFSVKLQQQELSIRPQPVQNHQLQSQSSTGDDVSSMNSFDMASIASGVLADNLHK-SATSASSKVKEAPEPTGKLSTISTSHQVCYATLQTQVVVPIPLHVTP-TFRTDLVDVRWRLHFEFVTTT----LIDFGIPNPESGELKAPSE-MPVETMVWNLPVTVYAANP-LQIYAPNQTFNLLIK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16664-1", "uniprot_id": "RGP1_YEAST", "id": "P16664-1", "name": "Guanine nucleotide exchange factor subunit RGP1", "aln": "MRAHRIDTFLIRENIKLEIIHESN-SYFGGEHISIAFRFKHLGSQHELFNYKEKLLTVDKAVEEKLEQQAKVQDDGEGTMENQTWSLKSLLGAFKRTGEPEESVDVDNMKMLNESKMLREKIQKQMYFHQPVTLISGYVQISGVFQYDSEVISESKFKQDEVKMVGLDIVPGHTTNSVLALEDGEHFKGKRNLTNYLNSDYTNVTNGLLFSESGSRGRTGTYNERTLMISNDTSIKTLPLLLIPQTLLFSEISLEPGEVRTFYFKSTKLPKDICPSYSSSKVASINYTLEVGADVLSDDNIEKFSNRVPITIAPYISSNAEQYTSRLDKPAIILKTGNIKELKPRLFTRKVSTASAVSFGRRKSSIIDIDSPLEDNEFVKRVKKNFIELVESNQNVSRDIDELIDLQMGVQFGKDEDSSDPEPNDSHFSNEMVTSAESSLRSDAVTKRRKSYSVRDNISNLEQKMWNDCSLVKSDENSNLLPQLINLQNAYQINRNNETMAKVSLSAPFYKTTDDINLVIELDPITTP-LLKVTSLTVSLESFEI------------------------------------INPKYKTEGKGIGSKPKGNSVYEKH------FICFDECKSVSVKLLPPRSPTNQITGQFKTDVFQHKWMIGLKFVIIAKTESITLDQFYEDKKGILFHSKENLEGEEFTCYVPIPILCTSEDFMGW------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: : : ** :. . ..: : * :*: .: : : . * : . : . *. :: .:**.:: *:*** : : :. :* : *:: . .: . *.: :. : :.. * * :* :. * . :* : ..* * : .. : .: : : *.*. . :. . : . *: :*: :::. . : .::*.*: * : .. . . . .. . . . : * . . . * . * * :.. :* : ::** : . : : ..: : : : :*: : :. : : ", "identical_positions": 37, "similar_positions": 131, "identity": "5.15%" }, { "cls_id": "homologset.agr.SGD:S000002546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29595-1", "uniprot_id": "NEDD8_MOUSE", "id": "P29595-1", "name": "Ubiquitin-like protein NEDD8", "aln": "MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLGQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71UE8-1", "uniprot_id": "NEDD8_RAT", "id": "Q71UE8-1", "name": "Ubiquitin-like protein NEDD8", "aln": "MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLGQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15843-1", "uniprot_id": "NEDD8_HUMAN", "id": "Q15843-1", "name": "Ubiquitin-like protein NEDD8", "aln": "MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLRQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ33-1", "uniprot_id": "NEDD8_DROME", "id": "Q9VJ33-1", "name": "Ubiquitin-like protein NEDD8", "aln": "MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDSILTPCV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03919-1", "uniprot_id": "RUB1_YEAST", "id": "Q03919-1", "name": "NEDD8-like protein RUB1", "aln": "MIVKVKTLTGKEISVELKESDLVYHIKELLEEKEGIPPSQQRLIFQGKQIDDKLTVTDAHLVEGMQLHLVLTLRGGN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::**********.:::: :* * :*** :********.*****:.***::*. *.:* :: * *****:****. ", "identical_positions": 45, "similar_positions": 22, "identity": "53.57%" }, { "cls_id": "homologset.agr.SGD:S000002547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACA2-1", "uniprot_id": "D4ACA2_RAT", "id": "D4ACA2-1", "name": "Methyltransferase HEMK2", "aln": "MAAPSVPTPLYGHVGRGAFSDVYEPAEDTFLLLDALEAAAAELAGVE-----LCLEVGAGSGVVSAFLAS---MIGPQALYMCTDINPKAAACTLETARCNRVHLQPVITDLVQGLLPRLKGKVDLLVFNPPYVVTPPEEVGSHGIEA------------AWAGGRNGREVMDRFFPLASQLLSPRGLFYLVTIKENNPEEIFK-IMKTRGLQGTTALCRQAGQETLSVLRFSKS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6SKR2-1", "uniprot_id": "HEMK2_MOUSE", "id": "Q6SKR2-1", "name": "Methyltransferase HEMK2", "aln": "MAAPSVPTPLYGHVGRGAFRDVYEPAEDTFLLLDALEAAAAELAGVE-----ICLEVGAGSGVVSAFLAS---MIGPRALYMCTDINPEAAACTLETARCNRVHVQPVITDLVHGLLPRLKGKVDLLVFNPPYVVTPPEEVGSRGIEA------------AWAGGRNGREVMDRFFPLAPELLSPRGLFYLVTVKENNPEEIFK-TMKTRGLQGTTALCRQAGQEALSVLRFSKS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5N5-1", "uniprot_id": "HEMK2_HUMAN", "id": "Q9Y5N5-1", "name": "Methyltransferase HEMK2", "aln": "MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLDALEAAAAELAGVE-----ICLEVGSGSGVVSAFLAS---MIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVKGLLPRLTEKVDLLVFNPPYVVTPPQEVGSHGIEA------------AWAGGRNGREVMDRFFPLVPDLLSPRGLFYLVTIKENNPEEILK-IMKTKGLQGTTALSRQAGQETLSVLKFTKS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQF8-1", "uniprot_id": "Q9VQF8_DROME", "id": "Q9VQF8-1", "name": "Methyltransferase HEMK2", "aln": "-----METPYTDHLSPEDFEHVYEPAEDSFLLLDALEKDLEYLDRLQP---SLCVELGSGSGVIITALAK---KLAGFSLCLATDINPKACNATRRTATRNGARLDSIRCSLADALRPR---SVDVLLFNPPYVVTSDEELQTQQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQLDDILSPRGVLYLLLLRENKPEEIIK-YLEGLQFRAVKFMERRIPGEHLCILKVTRYLASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03920-1", "uniprot_id": "MTQ2_YEAST", "id": "Q03920-1", "name": "eRF1 methyltransferase catalytic subunit MTQ2", "aln": "----MLPTPYV----KCDYDKVYEPAEDSFLILDCLEKEHDFLKQKFGNRLAIVCEIGSGSGIVTTFLMQNKIIPQENSIHLAVDINPWALEATLDTAKLNSCKSSFLEVIQADLNSSIRNNQVDVLIFNPPYVPAECVPDVPGSREE-----ADQWLDLALLGGKDGMAITDKLLRQLEQILSPDGVAYILFCARNKPKEVIKRFVDTYKWNVKLIETRKAGWEVLSVYSFTR-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** : .*******:**:**.** * : *:*:***:: : * . :: :..**** * .* ** * : . : .. . .**:*:****** : . : : **::* : * :: ::*** *: *:: .*:*:*::* :. . *: * *.: .:: ", "identical_positions": 56, "similar_positions": 56, "identity": "23.43%" }, { "cls_id": "homologset.agr.SGD:S000002548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0N6-1", "uniprot_id": "A0A8I6A0N6_RAT", "id": "A0A8I6A0N6-1", "name": "", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLGK-TLKPGLQGLLTGILPGLE-EGSEYYERTNTLLEKVAAAVE-QSAFYSALWGSLLTSPAVRLPGITYVLAHLN---------------------------------------RKLSMEDQLYIIGSDIELMVEAVSTSVQDSS-VLVQRSTLDLILFCFPFHMSQAT--------RPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAII--GPRSTRHSNP----EEHATYYFTTFSKELLVQAMVGILQVNGFGE--ESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDRAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCR-------RTLHARLEVGPGDSSDASEFQLTTFCSLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQ----PPLLSAGT---G-------------------------GVVQFPSGQNSAVKEWEDKK-VSSVSMENPTEVFEDGENPPSSRSSE------------------------------SGFTEFIQYQAERTDDLDRELN-GQGTATIPIGSTSSETETASTVGSEETVIQPPSTLTQGAAGRTGK-------AVQKTAMQCCLEYVQQFLSRLIHLYILHSDSFPQASAADHQSDLSRIQRDTSKWDRDSQGDAKERNIHTPK--TSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGEN------------------------------------INSMEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVP---SSSICEDVVSQQLTHKD-----------------------------------KKVRMEAHARFAVLWHLTRDLHVNKSS-FARSFDRSLFIMLDSLTS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGSREKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQS------------------SDSGCSQSSAGDNFSYEVDPENVSAHEDSHLAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDFDLGKEATKTEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLTDSSVSS-ETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQTNVFFSDGLDLENW---------------YSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKSNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHN------------------FRSSMYIEILISLCLYYMRSHYP------THVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFP----SFISDMLSKCKVQKVILHCLLSSIFSVQ--KWHSEKTAGKNMVAVEEG-FSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVM------TIPEESEAGF---------DFVVSDLEHVSPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEK------------------MGLAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNGRRQNKTPS--------RTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAK-DKKHLSLEVCMLQFFYAYIQR------------IPVPNLVDSWASLLVLLKDSIQ-LSLPAPGQFLILGVLNEFIMKNPSLEN--KKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDG----TNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKT------TFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLR-LPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSG-LEVRRQGIHQREFKPYVVRLAKLLRKRAK-----------------KNPEEDGSARTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNSFPSKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL99-1", "uniprot_id": "DOP1A_MOUSE", "id": "Q8BL99-1", "name": "Protein DOP1A", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLGLYEMYYLPLGK-TLKPGLQGLLTGILPGLE-EGSEYYERTNTLLEKVAAAVE-QSAFYSALWGSLLTSPAVRLPGITYVLAHLN---------------------------------------RKLSMEDQLYIIGSDIELMVEAVSTSVQDSS-VLVQRSTLDLILFCFPFHMSQAT--------RPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAII--GPRSTRHSNP----EEHATYYFTTFSKELLVQAMVGILQVNGFGE--ESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRQSFFLSRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSL----------ETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQ----PPLLSAGN---G-------------------------GVVQFPSGQNSTVKEWEDKKQVSSVSMENPAEVFEDGENPPSSRSSE------------------------------SGFTEFIQYQADRPDDLDRELN-GQGAATIPIGSTSSETETASTVGSEETVIQPPSTFTQGAAGRSGK-------AVQKTAMQCCLEYVQQFLSRLINLYIIHSDSFPQALAADHQGDFSRIQRETSKWDRDSQGDAKERNIHTPK--TSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLRTLMSACSQARDFRVQSAAVSLVMDLVGLTQSVAMVTGEN------------------------------------INSMEPAQPLSPNQGRVAVVIRPPLTQGNLKYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVP---SSSICEDVVSQQLTHKD-----------------------------------KKIRMEAHAKFAVLWHLTRDLHINKSS-FARSFDRSLFIMLDSLTS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGNGEKPLTMDEMENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQS------------------SDSGCSQSSAGDNFSYEVDPENANAHEDSHMAKASSPDDDVQQVVFDLICKVVSGLEAESESVTSELEIESLQTKSSDLDPGKEATKIEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLNDSSVPS-ETKSRQRSHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQANVFFSEGLDLENW---------------YSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHN------------------FRSSMYIEILISLCLYYMRSHYP------THVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFP----SFISDMLSKCKVQKVILHCLLSSIFSVQ--KWHSEKTAGKSMVAVEEG-FSEDSLINFSEDELDNGSTLQSQLLRVLQRLIVLEHHVM------TIPEENEAGF---------DFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEK------------------MAVAASASVTTINLGATK--------------------------------------------------VIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAK-DKVRK-LCFCRKFSFRTGADR------------IPVPNIVDSWTSLLVLLKDSIQ-LSLPAPGQFLILGVLNEFIMKNPSLEN--KKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDG----TNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKT------TFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAVLSSESDQYQKYLPDIQERLVESLR-LPQV-----------------------------------QVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSG-LEVRRQGIHQREFKPYVVRLAKLLRKRAKDEEDFKILEGLEMAKHQKNPEEDCSGRTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPVLYPNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JWR5-1", "uniprot_id": "DOP1A_HUMAN", "id": "Q5JWR5-1", "name": "Protein DOP1A", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLGK-TLKPGLQGLLTGILPGLE-EGSEYYERTNMLLEKVAAAVD-QSAFYSALWGSLLTSPAVRLPGITYVLAHLN---------------------------------------RKLSMEDQLYIIGSDIELMVEAVSTSVQDSS-VLVQRSTLDLILFCFPFHMSQAT--------RPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAII--GPRSTRHSNP----EEHATYYFTTFSKELLVQAMVGILQVNGFGE--ENTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQTEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYVARWFEECCR-------RTLHVRLQIGPGDSNDSSELQLTNFCLLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLHLSELTDSLRLCSKILSKVQ----PPLLSAST---G-------------------------GVLQFPSGQNNSVKEWEDKK-VSSVSHENPTEVFEDGENPPSSRSSE------------------------------SGFTEFIQYQADRTDDIDRELSEGQGAAAIPIGSTSSETETASTVGSEETIIQTPSVVTQGTATRSRK-------TAQKTAMQCCLEYVQQFLTRLINLYIIQNNSFSQSLATEHQGDLGREQGETSKWDRNSQGDVKEKNISKQK--TSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSELRSEKLETDCEHVQPPQWLQTLMNACSQASDFSVQSVAISLVMDLVGLTQSVAMVTGEN------------------------------------INSVEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVP---SSSICEDVISQQLTHKD-----------------------------------KKIRMEAHAKFAVLWHLTRDLHINKSSSFVRSFDRSLFIMLDSLNS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWNKSPCYPGEESDKHFMQNFACSNVSQVQLITSKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQIEILQS------------------SDSGCSQSSAGDNLSYEVDPETVNAQEDSQMPKESSPDDDVQQVVFDLICKVVSGLEVESASVTSQLEIEAMPPKCSDIDPDEETIKIEDDSIQQSQNALLSNESSQFLSVSAEGGHECVANGISRNSSSPCISGTTHTLHDSSVASIETKSRQRSHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDDDKKKSSNEKLKQTSVFFSDGLDLENW---------------YSCGEGDISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKAILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHN------------------FRSSMYIEILISLCLYYMRSHYP------THVKVTAQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFP----SFISDMLSKCKVQKVILHCLLSSIFSAQ--KWHSEKMAGKNLVAVEEG-FSEDSLINFSEDEFDNGSTLQSQLLKVLQRLIVLEHRVM------TIPEENETGF---------DFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWMASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVSVDQKHLFEARSGILSILHMIMSSVTLLWSILHQADSSEK------------------MTIAASASLTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKTTT--------RTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAK-DKKHLSLEVCMLQFFYAYIQR------------IPVPNLVDSWASLLILLKDSIQ-LSLPAPGQFLILGVLNEFIMKNPSLEN--KKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDG----TNLESDVEDMLSPAMETANITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKT------TFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLR-LPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSVAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSG-LEVRRQGIHQREFKPYVVRLAKLLRKRAK-----------------KNPEEDNSGRTLGWEPGHLLLTICTVRSMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNAFPNKDMKLENHKPCSSKARQKIEEMVEKDFLEGMIKT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UHQ6-1", "uniprot_id": "DOP1B_MOUSE", "id": "Q3UHQ6-1", "name": "Protein DOP1B", "aln": "-------MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSN-----LKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQK-LLLPSLQAFLVGLLPGLE-EGSEIYERTDALLLRLSVVVG-REVFYAALWGSVLTSPSIRLPASLFVVNHIS---------------------------------------RDSPGKEQKCMLGTDYQLTVRSLCASLLDAN-VLVQRNNLEIILFFFPFYTCLDPEERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTI--VPKSEISNSY----EDQCSYFFDKYSKDLLVEALAEILHQKFLDADLEERHHAYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNPLISTIKENRHASEIVKTVNLLVSSLSSDFLWDYMARRFEACFR--------PVTQTTAIG---EAISPPPTVSELCTLLVFLLDVIPL----------ELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQ----MPPSYLDLEPSS-------------------------GNSSPVKGRNSGIAMETEAVVAGDEEPSFPPLKSEDSGIGLSASSPE-----------------------------LSEHLRVPRVSAERDDIWKKDGT--MQATFLCIQELIANFASKNIFAASLTVSGEENKPEEPPGKGNKG----QTQSTEHPGRKSSWDPK-PITVPQFKQMLSDLFTVRGSPFKTRSSESLSSVPSSPHRKAATEWGVDQVVVELVG--SKEDCREALAAACHLLLDCATFPVYLSEEETEQLCETLFQTPGASDCSFPPWLKSLMTICCCVSDCSLQNIAIATLLEVINHSQSLALVIEDK------------------------------------MKRYKTSG-NNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAP---TANICEDIICHALLDPD-----------------------------------KGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLAC-TDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQE--------------------------------------------------------------------------------NSAEDLHRWFN------------------RKKPTCKEACGESEPQEGAPE------------ERLPRGQFTTVDREAIWAEVE-KEPEKCPPRSDLSEEDLP---YYVDLPDRMTSGGGDSSEHTE------------SADTSSGHTDSEN--TSTFSSPSHDLQDLSHEENCCAPIPIGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEADVELQAITTSRLLKQ------------------------------------------------QREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPN------------------VCPHSLLIELLTYLCLSFLRSYYP------CYLKVCHRDILGNRDVQVKSVEVLIRITAQLVSMAKSAEGKN----TEFIHSLLQRCKVQEFVLLSLSASMYTSQ--KRYGLATADRGGRLLAEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLG------QGQEEAETQP---------ALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGK-SLGWTVTPFVIQICKNLDDLVKQYESESVKFTISTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLRKEETQKRP----------------VDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWN-RKQARRHS--------KTKMVPVANTSQHTLVDLVCALSTLQTDSVLQLVKEVVKRPAQIKG-DEKSPLVDIPVLQFCYAFIQR------------LSIPDLQEAFPSLLGVLKEAAQ-LNLAPPGYFLLLSMLNDFVTRTPNLES--KKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLE----ESDAEDDVHSAAEASTMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSC-VHWKSVIDHLLTHEKT------MFKDLMN----MQSSSLKLFS----SFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLR-VGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEDES-RNSHKSNR-IKAPVADGNGSAGRVLSPS----DLTMYLSACKFLDTALAFPPDKMPLFQIYRWAFVPEVDTEHP-AFLSELEENHQECRPHTVRILELLRSRYG-------------------EIG--SSDEITRKKEFPLLRQHSVSCIRQLIPFFTTLNCAFKTQSQ----LPADVPGTAAPECP---------VTENPRVLRQLEECVEQDFLEHPEC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LFK5-1", "uniprot_id": "A0ABK0LFK5_RAT", "id": "A0ABK0LFK5-1", "name": "", "aln": "-------MDPEEQELLTDYRYRSYASVIEKALRNFESSSEWADLISSLGKLNKALQSN-----LKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQK-LLLPSLQAFLVGLLPGLE-EGSEIYERTDTLLLRLSVVVG-REVFYAALWGSVLTSPSIRLPASLFVVNHIS---------------------------------------RDSPGKEQKYMLGTDYQLTVRALCASLLDAN-VLVQRNNLEITLFFFPFYTCLDPDERAIPLLRRDIVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTI--VPKSEISSSY----EDQCSYFFDKYSKDLLVEALAEILHQKFLNADLEERHHEYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGPDLRLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSSLSTDFLWDYMARCFEECFR--------PVTQTTAIG---EAISPPPTVSELCTLLVFLLDVIPL----------ELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQ----MPPSYLDMEPTS-------------------------GNSSPIKGRNSG-VLETEAVVAGDEEPSFPPLKSEDSGIGLSASSPE-----------------------------LSEHLRVPRVSAERDDIWKKDGN--MQATFLCIQELIANFANKNIFAASLTVSGEESKPEGAPGKSIRG----QTQSTEHSGRKSSWEPK-PITVPQFKQMLSDLFTVRGSPFKTRSSESLSSAPSSPHRKAAAEWDVDQVVIELVG--SKEDCREALAAACHLLLDCATFPVYLSEEETQQLCEMLFQTPGPSDCSFPPWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDK------------------------------------MKRYKTSG-NNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAP---TANICEDIICHALLDPD-----------------------------------KGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLAC-TDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQE--------------------------------------------------------------------------------NSAEGLHRWFN------------------RKKPACREACGESELQEGAPE------------EHLPRGQFTTVDREAIWAEVE-KEPEKCPPRSDLSEEDLP---YYVDLPDRMASGGGDSSEHTE------------SADTSSGHTDSEN--TSTFSSPSHDLQDLSHEENCCAPIPVGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEAEVELQAITTSRLLKQ------------------------------------------------QREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPN------------------VCPHSLLIELLTYLCLSFLRSYYP------CYLKVCHRDILGNRDVQVKSVEVLIRITTQLVSMAKSSEGKN----VEFIHSLLQRCKVQEFVLLSLSASMYTSQ--KRYGLATADRGGRVFVEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLG------QGQEDSESQP---------ALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGK-SLGWTVTPFVIQICKNLDDLVKQYESESVKFTVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLKKEETQKRP----------------VDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWS-RKQSRRHS--------KTKMVPVASASQHTLVDLVCALSTLQTDSVLQLVKEVVKKPAQIKG-DEKSPLVDIPVLQFCYAFIQRGGVTKVEQETVRLSIPDLQEAFPSLLGVLKEAVQ-LNLAPPGYFLLLSMLNDFVTRTPNLES--KKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLE----DSDADEDVCDAAAASTMVSASAPSIYSVQALSLLAEVLASLLDMVYRSDEKERAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYSKRAWKKEVLELFLDPAFFQMDSSC-VHWKSIIDHLLTHEKT------MFKDLMN----MQSSSLKLFS----SFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLR-VGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEEES-RNSNKINR-VKVPAADGTGPSGGAVTPS----DLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHP-AFLSELEENHQECRPHTVRILELLRLKYG-------------------EIS--SSEEITRKKEFPLLRQHSVSCIRQLIPFFRTLNCAFKTQSQ----LPADVPGTTVPEFP---------VADSLRVLQQLEECVEQDFLEYPEC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3R5-1", "uniprot_id": "DOP1B_HUMAN", "id": "Q9Y3R5-1", "name": "Protein DOP1B", "aln": "-------MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSN-----LRYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAHAAVSVRPVLLTLYEKYFLPLQK-LLLPSLQAFIVGLLPGLE-EGSEISDRTDALLLRLSLVVG-KEVFYTALWGSVLASPSIRLPASVFVVGHIN---------------------------------------RDAPGREQKYMLGTNHQLTVKSLRASLLDSN-VLVQRNNLEIVLFFFPFYTCLDSNERAIPLLRSDIVRILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTV--VPESEISNSY----EDQSSYFFEKYSKDLLVEGLAEILHQKFIDADVEERHHAYLKPFRVLISLLDKPEIGPQVVGNLFLEVIRAFYSYCRDALGSDLKLSYTQSGNSLISAIKENRNASEIVKTVNLLITSLSTDFLWDYMTRCFEECFR--------PVKQRYSVR---NSVSPPPTVSELCALLVFLLDVIPL----------ELYSEVQTQYLPQVLGCLVQPLAEDMEALSLPELTHALKTCFKVLSKVQ----MPPSYLDTESTS-------------------------GTSSPVKGENGKIILETKAVIPGDEDASFPPLKSEDSGIGLSASSPE-----------------------------LSEHLRVPRVSLERDDVWKKGGS--MQRTFLCIQELIANFASKNIFGVQLTASGEESKSEEPAGKRDRDGT--QSLAANDSSRKNSWEPK-PITVPQFKQMLSDLFTARGSPFKTKSSESPSSSPSSPARKNGGEWDVEKVVIDLGG--SREERREAFAAACHLLLDCATFPVYLSEEETEQLCATLFQLPGAGDSSFPSWLKSLMTICCCVTDCYLQNVAISTLLEVINHSQSLALVIEDK------------------------------------MKRYKSSG-HNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHVTCVELFYRLHCLAP---TANICEDIICHALLDPD-----------------------------------KGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLAC-TDGAIGAAAQGWLVRALSLGDVARILEPVLLLLLQPKTQRTSIHCLKQE--------------------------------------------------------------------------------NSADDLHRWFN------------------RKKTSFREACAVPEPQESGSE------------EHLPLSQFTTVDREAIWAEVE-KEPEKYPLRGELSEEELP---YYVELPDRTAHGAPDSSEHTE------------SADTSSCHTDSEN--TSSFSSPSHDLQELSNEENCCAPIPMGGRAYPKRSALLAAFQSESFKAGAKLSLVRVDSDKTQASESFSSDEEADLELQALTTSRLLKQ------------------------------------------------QRERQEAVEALFKHILLYLQPYDSRRVLYAFSVLEAVLKTNPKEFIEAVSRTSMDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQVPN------------------VCPHSLLLELLTYLCLSFLRSYYP------CYLKVSHRDILGNRDVQVKSVEVLIRIMMQLVSVAKSSEGKN----VEFIHSLLQRCKVQEFVLLSLSASMYTSQ--KRYGLATAHHG-RALPEDSLFEESLINLGQDQIWSEHPLQIELLKLLQVLIVLEHHLG------RAHEEAENQP---------DLSREWQRALNFQQAISALQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGK-SLGWTVTPFVVQICKNLDDLVKQYESESVKLSVSTTSKRENISPDYPLTLLEGLTTISHFCLLEQANQNKKTMAAGDPANLRNARNAILEELPRTVNTMALLWNVLRKEETQKRP----------------VDLLGATKGSSSVYFKTTKTIRQKILDFLNPLTAHLGVQLTAAVAAVWS-RKKAQRHS--------KMKIIPTASASQLTLVDLVCALSTLQTDTLLHLVKEVVKRPPQVKGGDEKSPLVDIPVLQFCYAFLQR------------LPVPALQENFSSLLGVLKESVQ-LNLAPPGYFLLLSMLNDFVTRTPNLEN--KKDQKDLQEITQKILEAVGNIAGSSLEQTSWLSRNLEVKAQPQASLE----ESDAEEDLYDAAAASAMVSSSAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWRKEVLELFLDPAFFQMDTSC-VHWKSIIDHLLTHEKT------MFKDLMN----MQSSSLKLFS----SFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLR-VGQTSIVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFTQLEEDLKDEDESLRSTNKVNR-TKVSVPDANGPSVGEIPQS----ELILYLSACKFLDTALSFPPDKMPLFQIYRWAFIPEVDTEGP-AFLSDVEENHQECKPHTVRILELLKLKFG-------------------EIS--SSDEITMKSEFPLLRQHSVSSIRQLMPFFMTLNGAFKTQRQ----LPADSPGTPFLDFP---------VTDSPRILKQLEECIEYDFLEHPEC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z8M9-1", "uniprot_id": "A0A8M6Z8M9_DANRE", "id": "A0A8M6Z8M9-1", "name": "", "aln": "-------MDPEEAELQNDYRYRSYAAVIEKALRNFESSSEWADLISSLGKLNKALQSN-----LKYSLLPRRLIIGKRLAQCLHPALPSGVHLKALETYEVIFKIIGTKWLAKDLFIYSSGLFPLLGHAAMSVKPVLLTLYERYFLPLQR-ALLPSLQAFIMGLLPGLE-EGAEVYDRTDALLVKLSVLVG-QSVFYGALWGSVLICPLVRLPASLFIVAHFD---------------------------------------HSITAKEQKFMLGTDHRLVVKAVCLALQDSN-VLVQRNTLEILLYFFPFTTFQDPGECAIPLKQDEMISVVSAASLTLLRRDMSLNRRLYAWMLGLDIKGGMG--AADSSHYSTV----EEYTAFYFNTHSRELLVQALVNILKQKDIEANPDN-LIDYLRPFRIIISLLDKSEIGPLVLSDVLLEVVRAFYSYCIAMLG-DNGNNTSLTGSQLNSKIKENKNSSEIIKTVNMLVSAMSSNFLWDYMTRHFQICLS--------SLRDPVEKSP-SKSWSSPPSVTELSTLIIFLLDVIPL----------ELYAEIQTQYLPQMLGNMLQSLQSHMTSLSLSELTQAMRACFKVLSKIQ----MPVAYMDMEAESHTQDVEQTQIMMAGNNKVKESEQVDGNQNSVSAEDGLNGQEAQEVEAG--EAPYPPLRSEDSGLGLSASPSEQ-----------------------HLLPVLNGSEAASGVNCEAEDVWRRGGT--IENMSKCVQDIMAIVITRHLLDI---VDPEKKKKQEEANQLDAN-------ASPKSSKRSPLKRKGSRDLGLIKDRLAEFFNP--SKLRIHALHGLSRDGGKDHRPAQLEWMGSFQSKSKGE--ISESCRQAFTVICQLLLECTTFPVYFTEEENQELHTSMFNKTG-IEGTLPDWLRSLMTLCCLTKDYQVQHTAISSLLEMINHSQSLALVIHDK------------------------------------NQRYKNSD-ANPLSGQLQMVTLPPVYPVVLKTLEDSTDFYLRVSQVLWAQLDTERKEHHVSCVELFYRLHCLAP---SASICEDIICLGLLSGD-----------------------------------KVVCLEALHRFSVLWHLTREIQTSRSTSLNRSFDRSLFVVLDSLNN-QDGSVRAAAQNWLVRALSLSDVVRILEPVLLLLLDPKTQRSPIQSIKQN--------------------------------------------------------------------------------LSAGNVKALIW------------------RDR-SIPKSAGDSMTPGCQTE------------ESFVN-RITIVDREALWAELE-RDPELTPPDSPTISQSES---DETEGEDEEVE-EEEESEHTE------------SADTSGAQNSTEN--SSSSSAPYLQRHEDGSVEEDAVPN----------------------------GLQRVDSERTQVSDSLSSDE-DDGQLEAMAKTRQLKR------------------------------------------------QREKREAVDSLFRHVLLYKQKYESSQILYAFTILETILRTSAGPFVEALSSTSLDCSSIAHLNLIQNLLQRHRQAQDGGSFYGQLQNSTPPSGGTPDASQPASSPLHSPSCPPTLLLELLTSLCMRYLRSHYP------SYASVPTRQLQANREVQVKSVEVLTELMIQLVRVAQQNGDTKGTAGLEAVRNLLWGYKVQQYVLLTLSASMYVCQRVDRPDQHTLPEEDQGEDGGEISEESLINFGRDGTWAEHPLQIALLKLLKVLIVLEHHVCPPHTKPQEHDQGQSNPQRRAEPPSSALAREWQTAVMFQQSIKAVRYVSSQPITAQGMFVSAAARALHPQYGCAMHPAWVTLLCDVLPYLGR-SLAIIVSPIIAQICRNLDELVKQHEHDGIKGSHNGTLKRENIAPDYPLTLLEGLTTITHYCLLD----HKKATAGCDVPDLRNASNAILEEFPHMISSMALLWGVVKGCDSTH----------------------GSRATPTSVYFKSTKILRQKVLEFLMPLTQQFGVQVMASVAAVWNSRKSRKRRS--------RNKILPDASDSQMTLVDLVKALNTLRTDTILQLIREVVKKPHQIKG-DQKSTLVDIPMLQFSYVYIQS------------LTAQALQENINPLLCLLRESVQ-LNLAPPGHFLLLGILNDCVNRLPNIDN--KRDTKELQEVSQRILEAVGAVAGSSLEQTSWLSRNLEVKAQPQVCLQGDEDDHDANEFEEYAGQGSTMVSSSAPSVFSVQALVLLAEVLAPLLDMVYRSDEKEKAVPLISRLMYYVFPYLKNHSAYNMPSFCAGAQLLSSLSGYAYTKRAWKKEVLELFMDPLFFTMESSCSYHWRSIIDHLLTHEKT------MFKDLMS----MQSSSLKLFN----SAEQKPMLLKRQAFAMFSGENDQYHFYLPLIQERLTENLR-VGQSPSVSAQMFLMFRVLLLRISPQHLTSLWPIMVTELIRIFNRLEKALLDDKEVTKSKLRGG-------HDKNG--LLCFPQA----ELDMYLSACKFLDTAVSFPPDHMPLFQMYRWAFIPEVDVDHYDGPGNTLLEGEQECKPHIVRILDGINRRYG-------------------ELNGTAAESSTDRVEFPLLTLRSLYSIVDLVPFFNTLCCSFNGSSS----AHLS---HYAADYP---------PSSSDQVMKRLEHITEGEFLDGMDS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBE8-1", "uniprot_id": "DOP1_DROME", "id": "A1ZBE8-1", "name": "Protein DOP1 homolog", "aln": "--MESADALVEEQKLMAEAKYRTYMTNIDKALRNFEYSSEWADLISALGKLSKAISSN-----TQYQVIPRRLKIAKRLAQCMHPALPSGVHLKALETYSVIFSKTGPERLAT-EFIYSAGLFPLLGYAAMNVRPALLAIYETYFVPLGD-KLRPALSGFLNGVLPGYD-CGLDHFERISALLKQVCNAVN-PMHFYTVLWESVANNAAIRLPAITYLLEHFN---------------------------------------KRLDMQEQIYIMGHNREIMMSALCVCLNDSL-ILVQRNTLEFLLLGFPMHTVLLS--------EDDLVKLVTNGLNTILRRDMSLNRRLFSWLLGSEVAKNSP--TYDTLSLDTSNAPLEEEPEPYFVKHSRHILIKALITTLRLS------LECAPMDLKPYRIMLSLLDKAEIGSAVLDYVLHDIIRAMYISS---------------------------GNAEALKSANLLFATFDPAYIWSYMTNMFEKACQQANSMQEKSQAGETSGKYACDVGSGDPCVLEICVLTEFLLETVSL----------EMYTETTRVYLPKVFLAITQLLSLHMDHISSNEITASLKLCMKIVSRVQPMITSPIKLNKLIEQSGGSSSDEKITMNSASDAGKTEAGAQGNSLEKSKSDSRLNQFAENTLHSADPNDEELIHRSASNQSVGRQSPNKKKAKSISRLSELDKDISASDTGQQSSSDLDTPRSIKKLKAKAKVPFIRSPKKQRPKDMVLIQSNTSAEVSDGPSAEEPKSAPPDQTPQFQLDEESRATQQRGFSILEKCIRQYEIFFEVYLSRKLLHIESEPKECSVKVQLQRTTSTIHTSNLFMAEQVLDHECPVRESQIERLFNLLRVDIVPRSKQLQRLLNRSLPLPASASELSSDSEAQEEKQQSLLIDGQTQRSVQQLAELQLSPSLRGAVKLAATLLVEMSTFPNCNKHVVLDKNEPELPNWLKVLCLVACFAQSDKELQVASITTLFDLISLLRSQIEHTTSPGVTFVVMLPLLKFGHVSYMEQHTRVFQLVSSILWDYLGTAGIDPAQIAALLHQLHSCLESGLVETVIGNRMQSQHLLQMQSQSRSDLGKAAIRNFQMERLAEAQLLCPTESTERLRESQARSFKKFELLWHLGRDKQ------TARGFEKTLLKVLDTLALPHYMSERTFVTNWLQASLLRGDLARLTKPLYKILLSASSKRVGIVHMQQLYRESETEVTPAFERDVYAISSEQGNVKYHHMETSSGNKKKSPIRNFPKKIFGVTLSGGKANKVSNFVSDKSTVATCSEATQDMNTIGLIINPLENANDFDDETDLEEPRIEIPHKETPLEQKLASAMDESEQPSQEQPANQPDNSLQYDQDITDHSDSSDFESDSELRETSIEKEDSITVSSSAGVSDDVKRFVGDCESVTDALTQHEKIKSRKTYRLTREKTPGENSLNSLEQKDHDSISELQADALPADEYFREDKKLGKRKKVLTSGEKKRLSCISKTSTDSNISGSHVEQPEQEEETEPGTESTINVEDKRRNLSLETSKLQPDMQKTLEKGKQNVEILRQNNAAAAAAAAAAAEEQISVRSSMKSTVSLTDAAHLYHNHLLIYLAIYDTRQTLYALQTLRNIICCDKRTFLCLSITTSFSSAS------LKQLLVRHRKSISGKGFDGSVGNSEYAQG-----------------YRGCMQLELLVTLCLFYARGYFQKESLDAQRQSPTLQDIVNNRRIQLESIELLTLICSELIEIVKGMGRGLAN----YIADLLARAKLQKVMLHCLNSSVCSYG-----------LKGNTNSGSYAEQVLSFNDPQDDQLHADCFQLQLLRLLLAVIRLEHEVH------QLRQDTPPAAGE-------DSAGNASPTRLAEGATANVKYLPNCLISQQPMFLAAVLGALQQERLRHLHRNWTDLVTSSLNCFSFGSLTNIVISVVHQLCSNLDRISKMG-----------LPQQRHFPPDYVVSQLEALTILCHYCLLDNTQQTALSHLFNQAYPQTSSSAQSSSTGQLLNSIVHSFLSASESSTSAPAPRNPQLQAARNAVLSHLPRIMSSVAAIWDSELGQLRPVRQQLLEFLSPVSLHHGSNFLAAVAVTWQQRGIATNMNGLSIAEQFQRNSVLQACPAQLSLVSLVSSIRVMPMDSFVMTLHHVVRSPPPIHR-PPAQLSIEVSALELFYFYMKS------------APAPQLADAWSSLLALIRDG---LNLTPPAQFALLMLLNEFVQRCPQMPFQDKKEVRELHDVTSRLVDSLSSVAGSCLEQTTWLRRNLAVKEDTDGLAKD------------------NSVGGGGLQQYSLQAQSVLAAILSNLLDVAYGSQEKDKVVNIVTPLLYNITPYLKNHTARNVPFFYACSALLASLSGYQYTRKAWRKDMLDLLLDNAFFQMHLSCLPFWRMIMDSLMTYDNT------TFRELMTRVSLSQAGSLNIFTSRDQEYEQRAMLLKRLAFVIYCSEFDQHNKYMPDIQEQLANSLRLVPMGPSVQAAVFLCFRVLLLRMSPDHVTSLWPIIIAEMVQVFLQMEQELKSESEERNQQLRLPSGIDVSWSAASGASNGYNSQTPMQHWRSVQLEACKLLELGCVLPATKLPHFQMYRWAFVGTEFDVHEEEVCLPNGSLENLATLPSALYVPHVRRVAR---------------LMDMKYTSQSPILQRPSNRHLMLHFQQLQSLQELYAFFTTLGISCPQPRN------------FADTEN-----------DVANCLKEIEEVLANDFLEKLPSITTPR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03921-1", "uniprot_id": "DOP1_YEAST", "id": "Q03921-1", "name": "Protein DOP1", "aln": "MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADYIASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYIFEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPLISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWLTRKFPSLNAVPHLVNKIKMEAEENPSETETNDSHLDRKKRKEEAFKVLLPAAKDLVTPEPGLLIRCLVGCLEDENDILIKRSVLDLLLQRLRLDSPVLN----VLITSEDKKLLIMSCCRTTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKSANEESNVYFTKYGLSALLEGLSDLLSEE----------ESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSS---------------------------EKFKQNEQIMKTARTFFDNTETNIIWGKLFQELEDIKN--------------------------------LKILDFVLTNFNIG----------NDEEIIVRHLPLILLTLLALPSNDKDFDNIYKLQK-FSLYNKLLNYIP--------------------------------------------------ERALLPLSHSKLKHDDEVSCEELLAKIRGFYTNVSNPS--------------------------------------SILEKENIAERLPPFTTEDLTFLIADLIQKKLLSSLWDLENINESSK-----------------------------------------------------------------------------------------------------------------LFIAIFEKIPESEELKGRSHISWSDKKITQSIFEAIPRLCESNNDAKSE--------EIVGIVEIFGNYLYSR------------------------------------------------------------------MEFIESMKLLKVVMMAVWKSLKD--PRHQILGVKNLKTLNRFIP----SKFIESALVYTFVEEE-------------------------------------DISERLSVLDLLWTQLDSDS--------NLIRRPLELILGELFD-DQNPFYLTVSKWILSILNSGSASRLFYILTDNILKVN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEKERLDERD---------------------------------------------------------------------------------------------DLDMLTYEFQMLAYVLKTNNG--------------------RTRKVFSTELTSIKSSTIWKNEDVSTYKS------------------------LLLVTLMRFLNIK--SN---------------------THAKSIRSALILLDILLDGTEQN--------------------FKDIVIFLLQMSSKYIA--------------------------------EEGIEPELIAVSLLDIVSKVLRLSHDNG-------IKLDIFDDN-------------AAHLKYIDFLVTSVSNMKSPLIVTAYVKLLSESIVYFENSIFRMILPLSASLVQCVQRLFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVS---------------NVFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSND-----------------DSSLDATNHNSYKFKFRSKKLLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNK--------PAITIPHLLYGVIIRYNRTASVKFSNRDGSRSSTTKLTKGEPSMLK-----RLSGESIIAFLFNYVDS------------VENSAMEEFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVS------KTQFGEQKRVRREISDVFFKYLPNAFINFTNLYR---------------------------------------GHPDSFKDLEFVVWRVQYIVNDQIGGDKFN--TTLATIVNQCLTPYIKPKSEKTIPGY--VLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKIIYEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLMVSPNDAYLLHFSSLISCIFHYLV--SKDIKLKGSCWILLRVLLLRFSESHFNDYWSMISYCLQTNLQEFYESLQIQSEVDPQT---------------------------------ILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCVYKT-NSFVALVDEIAEFKDYEITKTDDLELPTT-----------------------------LKDGLPLLRGIHKIERHTQLRSFFQNLSYLHYEKVYG----------------------------LGSVDLYGCGEDLKKDILS---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : : :.: : :::**..*: :**** *::**.* *.:.. :* :.:**:..: ****.*** *:**.* **. * : **. :: *::**: *::.*:. *: :*: * : * * : :: .:*** : . : *: : : *: .*: : ** . :: :: :: : : : .: .: * :*::*. *:: * : : : :: . * :*******:: *:** : . :: :* ... *::.: * . * .:*: ::::*: *:*. :: :: :. : : :*:.. :. .. :*. : . :: : *:* . : * :** :: : . :: : *::. : : . . . .. . : : . : . : . . . .. : :: : .. : : . * :* * . : . : : : : : . : ::* . . : :.* :*. * . *: * . *: : :* . .: : * : : :: . ::: . : . : . : :: : : : : *:. : * : .:. :: * * : : ** :: :: *.* : . :: ::. :. : *: : : .*: : : : * : :. : . . : . : : . . :: : .: : : . : : :* .::: .* . : :* :: : . * : : : : .: : . ..: : : * * *.: .: : ::: .:: : : : : **:: :: . * : * : :* . ::*: :*: : : : * : : : : ::. : :: . . :.: . * : * : :: : . * : ::. : . : . * : : : * :.: *..** *: : :. : : :.: :. : : :* .** * . ::*. ", "identical_positions": 133, "similar_positions": 405, "identity": "4.67%" }, { "cls_id": "homologset.agr.SGD:S000002549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97865-1", "uniprot_id": "PEX7_MOUSE", "id": "P97865-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "MS-----AARTLRVPGRHGYAAEFSPYLPGRLACAAAQHYGIAGCGTLLVLDQNE---------SGLQIFRSFDWNDGLFDVTWSENNEHVLVTCSGDGSLQLWD--TAKATG-------PLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDPTVGNSLCTFRG---------------------------HESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTTGVR--IVIPAHQ-TEILSCDWCKYNENLVVTGAVDCSLRGWDLRNVRQPVFELLG-------------------HTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDPLLETVEH---------------HTEFTCGLDLSLQS-PTQVADCSWDETIKIYDPVCLTVPG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00628-1", "uniprot_id": "PEX7_HUMAN", "id": "O00628-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDE---------AGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWD--TAKAAG-------PLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRG---------------------------HESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVR--IVIPAHQ-AEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLG-------------------HTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEH---------------HTEFTCGLDFSLQS-PTQVADCSWDETIKIYDPACLTIPA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSN7-1", "uniprot_id": "Q9VSN7_DROME", "id": "Q9VSN7-1", "name": "Peroxin-7", "aln": "MQ------TQTHTTTDRHGYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLGELCRLEWSDGLFDVAWCPYAADIAATASGDGSLQIWCGLDGESASNQLTPKQPLICLQEHKNEVYSLDWGEKWNYHTLLSGSWDCTLKLWDCNRQNSITTFVG---------------------------HNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDFAGKPLMSIEAHA-SEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYS-------------------GEFAVRRLACSPHSAAVLASANYDFTTRIWNLERGESAQEVNAR---------------HTEFVCGLDWNPHR-THQLADCGWDSLANVYTPQCLSGDLVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39108-1", "uniprot_id": "PEX7_YEAST", "id": "P39108-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "--------MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILEIDRS--------GRIVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDT-TFKEFP--------IAIFKEHEREVFSCNWNLVNR-QNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEITKMVDPLNAIILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKNQNNFLVHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNESATIKRTVPGQLHNSSCINEIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETYKTNSTDATKGSIFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGLG-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **. .:**: . * *:.. :*:.* *.*::*: : : . : .* ***::* . ...***:*::: : : :** .**:* :*. : .:*.*** ::*:*. :*: *: :.. :* : :** . . * * : ::: . : : .* * * **: :: ::.**. * :* **:* :. *:*:: **. : :* *..**:* *:*. : *. *:**. * * . . :*. .** :: ", "identical_positions": 71, "similar_positions": 98, "identity": "17.4%" }, { "cls_id": "homologset.agr.SGD:S000002552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ70-1", "uniprot_id": "A0A0G2JZ70_RAT", "id": "A0A0G2JZ70-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASPYSGLTAVADVIKDLDTQIALIGLGPHSSKKKQDLDKLYELKCKAGQIMNQFGPSALINLSSFSSIKPE-------PASTPPQGSMANSTTVGKMPGTPGTGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE65-1", "uniprot_id": "TAF12_MOUSE", "id": "Q8VE65-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQFGPSALINLSSFSSVKPE-------PASTPPQGSMANSTTVGKIAGTPGTGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16514-1", "uniprot_id": "TAF12_HUMAN", "id": "Q16514-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQFGPSALINLSNFSSIKPE-------PASTPPQGSMANSTAVVKIPGTPGAGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49905-1", "uniprot_id": "TAF12_DROME", "id": "P49905-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDLFTTFDSNGVAEHHLHHNHNSTSSASGLLHDPPMASPSQHSPMTNNSNSSSQNGG-------PVSGLGTGTGPISGGSKSSNHTSSAAG---SENTP------------------------------------------------------------------MLTKPRLTELVREVDTTTQ-----LDEDVEELLLQIIDDFVEDTVKSTSAFAKHRKSNKIEVRDVQLHFERKYNMWIPGFGTDELRPYKRAAVTEAHKQRLALIRKTIKKY---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03761-1", "uniprot_id": "TAF12_YEAST", "id": "Q03761-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF12", "aln": "MSSNPENSGVNANNNTGTGNADAITGAQQNMVLQPRQLQEMAAKFRTLLTEARNVGETTPRGKELMFQAAKIKQVYDALTLNRRRQQAAQAYNNTSNSNSSNPASIPTENVPNSSQQQQQQQQQTRNNSNKFSNMIKQVLTPEENQEYEKLWQNFQVRHTSIKEKETYLKQNIDRLEQEINKQTDEGPKQQLQEKKIELLNDWKVLKIEYTKLFNNYQNSKKTFYVECARHNPALHKFLQESTQQQRVQQQRVQQQQQQQQQQQQQQQQQQQQQQQRQGQNQRKISSSNSTEIPSVTGPDALKSQQQQQNTITATNNPRGNVNTSQTEQSKAKVTNVNATASMLNNISSSKSAIFKQTEPAIPISENISTKTPAPVAYRSNRPTITGGSAMNASALNTPATTKLPPYEMDTQRVMSKRKLRELVKTVGIDEGDGETVIDGDVEELLLDLADDFVTNVTAFSCRLAKHRKSDNLEARDIQLHLERNWNIRIPGYSADEIRSTRKWNPSQNYNQKLQSITSDKVAAAKNNGNNVASLNTKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. .: : ..: *. * . .... . *. :::* :* :**: *. :* ****:**:: ***: ... :. :*:****..:*.:*:***:**::*: ***:.::*:*. :: :: ::*:: * . ", "identical_positions": 38, "similar_positions": 64, "identity": "7.05%" }, { "cls_id": "homologset.agr.SGD:S000002554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRW8-1", "uniprot_id": "EKI2_RAT", "id": "D3ZRW8-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPVPCSPFYLRRQEACPQCSWSMEEKA------------------VASASCWEPPGPPR-------------AAVPCFAIAVDQDD---ILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRD------CVLVRVYGEWT-----------------------ELLVDRENEIRNFQLLRAHGCAPKLYCTFQNGLCYEYMQG-VALGPEHIREPQLFRLIALEMAKIHTIHAN-GSLPKP--TLWHKMHRYFTLVKD-----EISPS-------------LSADVPKVEVLEQELAWLKEHLSQLDSP--------VVFCHNDLLCKNIIYDSDKG---------------------------------------------------------------------HVRFIDYEYAGYNYQAFDIGNHFNEFAG--------VNEVDYCRYPAREIQLQWLRYYLEAQK------GTAASPREVERLYAQVNKFALASHFFWALWALIQ---------------------------------------NQYSTINFDFLRYAVIRFNQYFKVKPQVSALEMPK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7MCT6-1", "uniprot_id": "EKI2_MOUSE", "id": "A7MCT6-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKA------------------VASAGCWEPPGPPR-------------AAVPCFSVTVEQDD---ILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRD------CVLVRVYGERT-----------------------ELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQG-VALGPEHIREPQLFRLIALEMAKIHTIHAN-GSLPKP--TLWHKMHRYFTLVKD-----EISPS-------------LSADVPKVEVLEQELAWLKEHLSQLDSP--------VVFCHNDLLCKNIIYDSDKG---------------------------------------------------------------------RVCFIDYEYAGYNYQAFDIGNHFNEFAG--------VNVVDYSRYPARETQVQWLRYYLEAQK------GTAASPREVERLYAQVNKFALASHFFWALWALIQ---------------------------------------NQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVF9-1", "uniprot_id": "EKI2_HUMAN", "id": "Q9NVF9-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPQPRASFHLRRHTPCPQCSWGMEEKA------------------AASASCREPPGPPRA------------AAVAYFGISVDPDD---ILPGALRLIQELRPHWKPEQVRTKRFTDGITNKLVACYVEEDMQD------CVLVRVYGERT-----------------------ELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQG-VALEPEHIREPRLFRLIALEMAKIHTIHAN-GSLPKP--ILWHKMHNYFTLVKN-----EINPS-------------LSADVPKVEVLERELAWLKEHLSQLESP--------VVFCHNDLLCKNIIYDSIKG---------------------------------------------------------------------HVRFIDYEYAGYNYQAFDIGNHFNEFAG--------VNEVDYCLYPARETQLQWLHYYLQAQK------GMAVTPREVQRLYVQVNKFALASHFFWALWALIQ---------------------------------------NQYSTIDFDFLRYAVIRFNQYFKVKPQASALEMPK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HBU6-1", "uniprot_id": "EKI1_HUMAN", "id": "Q9HBU6-1", "name": "Ethanolamine kinase 1", "aln": "----MLCGRPRSSSDNRNFLRERAGLSSAAVQTRIGNSAASRRSPAARPPVPAPPALPRGRPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIHVPPGSPE---------------VPKLNVTVQDQEEHRCREGALSLLQHLRPHWDPQEVTLQLFTDGITNKLIGCYVGNTMED------VVLVRIYGNKT-----------------------ELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPKHVCNPAIFRLIARQLAKIHAIHAHNGWIPKS--NLWLKMGKYFSLIPTGFADEDINKR-------------FLSDIPSSQILQEEMTWMKEILSNLGSP--------VVLCHNDLLCKNIIYNEKQG---------------------------------------------------------------------DVQFIDYEYSGYNYLAYDIGNHFNEFAG--------VSDVDYSLYPDRELQSQWLRAYLEAYKEF-KGFGTEVTEKEVEILFIQVNQFALASHFFWGLWALIQ---------------------------------------AKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKVPE---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LLY9-1", "uniprot_id": "A0ABK0LLY9_RAT", "id": "A0ABK0LLY9-1", "name": "ethanolamine kinase", "aln": "---------------------------------------------------------------------------------------------MANYIHVPPGSPE---------------VPKLDVTVQDQEEQRCRDGALSLLQHLRPHWDPREVTLQLFTDGITNKLIACYVGDTMDD------VVLVRIYGNKT-----------------------ELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPQHVCNPAIFRLIARQLAKIHAIHAHNGWIPKS--NLWLKMGKYFSLIPTGFADEDINKR-------------FLSEIPSPQLLQEEMTWMKEILSSLGSP--------VVLCHNDLLCKNIIYNEKQG---------------------------------------------------------------------DVQFIDYEYSGYNYLAYDIGNHFNEFAG--------VSDVDYSLYPDRELQGQWLRSYLEAYKEY-KGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQ---------------------------------------AKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKMPE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4V0-1", "uniprot_id": "EKI1_MOUSE", "id": "Q9D4V0-1", "name": "Ethanolamine kinase 1", "aln": "---------------------------------------------------------------------------------------------MANYIHVPPGSPE---------------VPKLDVTVQDQEEQRCRDGALSLLRHLRPHWDPREVTLQLFTDGITNKLIACYVGDTMED------VVLVRIYGNKT-----------------------ELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPQHVCNPAIFRLIARQLAKIHAIHAHNGWIPKS--NLWLKMGKYFSLIPTGFADENINKR-------------FLSEIPSPQLLQEEMTWMKELLSSLGSP--------VVLCHNDLLCKNIIYNEKQG---------------------------------------------------------------------DVQFIDYEYSGYNYLAYDIGNHFNEFAG--------VSDVDYSLYPDRELQGQWLRSYLEAYKEY-KGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQ---------------------------------------AKYSTIEFDFLGYAVVRFNQYFKMKPEVTALKMPE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55229-1", "uniprot_id": "CHKB_MOUSE", "id": "O55229-1", "name": "Choline/ethanolamine kinase", "aln": "------------------------------------------------------------MAADGTGVVGGGAVGGGLPK-----------DGLQDAKCPEPIPNRR-----------------RASSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSVGGEPREVLLRLY----GAIL-------------------QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPS-RPLKTQELRDPVLSGAIATRMARFHGMEMPFTKEPR---WLFGTMERYLKQIQDLPSTS-----------------LPQMNLVEMYSLKDEMNSLRKLLDDTPSP--------VVFCHNDIQEGNILLLSEPD----------------------------------------------------------------SDD--NLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPTDYPTREQQLHFIRHYLAEVQKG-EILSEEEQKKREEELLLEISRYSLASHFFWGLWSTLQ---------------------------------------ASMSTIEFGYLEYAQSRFQFYFQQKGQLTSSPSS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54783-1", "uniprot_id": "CHKB_RAT", "id": "O54783-1", "name": "Choline/ethanolamine kinase", "aln": "------------------------------------------------------------MAADGTGVVGGGAVGGPLSK-----------DGLLDAKCPEPIPNRR-----------------RSSSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSMGGEPREVLLRLY----GAIL-------------------QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPS-RPLKTQELRDPVLSGAIATKMARFHGMEMPFTKEPR---WLFGTMERYLKQIQDLPSTS-----------------LPQMNLVEMYSLKDEMNHLRTLLDATPSP--------VVFCHNDIQEGNILLLSEPD----------------------------------------------------------------SDD--NLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPADYPTREQQLLFIRHYLAEVQKG-EVLSEEEQKKQEEDLLIEISRYALASHFFWGLWSTLQ---------------------------------------ASMSTIEFGYLEYAQSRFQFYFQQKGQLTSFLSP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y259-1", "uniprot_id": "CHKB_HUMAN", "id": "Q9Y259-1", "name": "Choline/ethanolamine kinase", "aln": "------------------------------------------------------------MAAEATAVAGSGAVGGCLAK-----------DGLQQSKCPDTTPKRR-----------------RASSLSRDAERRAYQWCREYLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLY----GAIL-------------------QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPS-RPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPH---WLFGTMERYLKQIQDLPPTG-----------------LPEMNLLEMYSLKDEMGNLRKLLESTPSP--------VVFCHNDIQEGNILLLSEPE----------------------------------------------------------------NAD--SLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKG-ETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ---------------------------------------ASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54804-1", "uniprot_id": "CHKA_MOUSE", "id": "O54804-1", "name": "Choline kinase alpha", "aln": "-----------------------------------MKTKFCTGGEAEPSPLGLLLSCG-GNAAPTPGVGQQRDAAGELES-----------KQLGGRTQPLALPPPPPPPLPLP---PPPSPPLADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDSIASVGDEPRKVLLRLY----GAILKMRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPS-RRLDTEELRLPDISAEIAEKMATFHGMKMPFNKEPK---WLFGTMEKYLNQVLRLKFSREAR--------------VQQLHKILSYNLPLELENLRSLLQYTRSP--------VVFCHNDCQEGNILLLEGQE----------------------------------------------------------------NSERRKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYTYEKYPFFRANIQKYPSRKQQLHFISSYLTTFQNDFESLSSEEQFATKEDMLLEVNRFALASHFLWGLWSIVQ---------------------------------------AKISSIEFGYMEYAQARFEAYFDQKRKLGV--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01134-1", "uniprot_id": "CHKA_RAT", "id": "Q01134-1", "name": "Choline kinase alpha", "aln": "-----------------------------------MKTKFCTGGEAEPSPLGLLLSCG-GSAAPTPGVGQQRDAAGELES-----------KQLGGRSQPLALPPPPPPPLPLP---PPPSPPLADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDSIASVGDEPRKVLLRLY----GAILKMRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPS-RRLDTEELCLPDISAEIAEKMATFHGMKMPFNKEPK---WLFGTMEKYLNQVLRLKFSREAR--------------VQQLHKFLSYNLPLELENLRSLLQYTRSP--------VVFCHNDCQEGNILLLEGQE----------------------------------------------------------------NSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYTYEKYPFFRANIQKYPTRKQQLHFISSYLTTFQNDFESLSSEEQSATKEDMLLEVNRFALASHFLWGLWSIVQ---------------------------------------AKISSIEFGYMEYAQARFDAYFDQKRKLGV--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35790-1", "uniprot_id": "CHKA_HUMAN", "id": "P35790-1", "name": "Choline kinase alpha", "aln": "-----------------------------------MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLES-----------KQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLY----GAILQMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPS-RRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPK---WLFGTMEKYLKEVLRIKFTEESR--------------IKKLHKLLSYNLPLELENLRSLLESTPSP--------VVFCHNDCQEGNILLLEGRE----------------------------------------------------------------NSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQ---------------------------------------AKISSIEFGYMDYAQARFDAYFHQKRKLGV--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMF4-1", "uniprot_id": "Q8IMF4_DROME", "id": "Q8IMF4-1", "name": "", "aln": "MKQRNLRNNKALKRLQQPDNKNLNCCLSKRCNYENIWQHFNSNATLEEIRHAAARICRDYLTGPWKVVTPESLVVKRISGGLSNFLYYVSLPDLNDYDELDEQKQQQEDIIGATATVTNRSGVFIHDDESAAKAVGVTLMARELINNDDVADAAPGATQAHKRQRCDSNSRECSSSKRLHAPKQQPREVLLRIY----GQTHG-----------------DHALESMITESVVFALLSERNYGPKLHGIFPGGRIEQYIPA-RALTTAELGEQRILKRVAEKMGEIHSLNIPMSKEPD---WIWNCMQRWVSGLESIVNGSVQTNQKSS-------VLKKQMELMRTFDYVQEMAWIRSIIDEGDYP--------VVFCHNDLQEGNILMRQPSAGQNERTPRESISSLRSNFDETLGDSLDGNSNISDTETHKSRSVSPSPCPELDTTNDSALDSSFMADNEPDLIIIDFEYCAYNYRGYDLANHFIEWTFDYTNPQFPYFYHNSSNCATVQQRRDFIVNYLKKFHDDENYNITGQELMKVD---AEIQFFTMLSHLFWSLWSVIN---------------------------------------VTS-AIEFGYWEYGIARILEYQKLKAAYQAN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03764-1", "uniprot_id": "EKI1_YEAST", "id": "Q03764-1", "name": "Ethanolamine kinase", "aln": "----------MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDG------------EMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPP--------LLMRIFG-----------------------DSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKD---------------------------------------------------------------DISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYN--DVQSFKSHIDKYPKEEDILVFAQSYINHMNEN----HVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :*:*:: . * : * . .*:* * * ::: . .. :* .: :* : : .:.. : : : :*:**** *:: . : ::*:**.. * :*:.**: *: . : : *: : : : ::::* **: :: .*.: : :: : ", "identical_positions": 29, "similar_positions": 67, "identity": "4.42%" }, { "cls_id": "homologset.agr.SGD:S000002555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01205-1", "uniprot_id": "ODO2_RAT", "id": "Q01205-1", "name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "aln": "MLSRSRCVSRAFSRSL--SAFQKGNCPLGRRSLPGVSLCQGPG----YPDSRKMVINNSSVFSVRFFQTTAVCKNDVITVQTPAFAESVTEGDVR-WEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPATAYKAAPEAPAAPPPPVAPVPTQMPPVPSPS-------QPPSSKPVSAIKPTAA----PPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2G2-1", "uniprot_id": "ODO2_MOUSE", "id": "Q9D2G2-1", "name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "aln": "MLSRSRCVSRAFSRSL--SAFQKGNCPLGRRSLPGVSLCRGPG----YPDNRKMVINSGSVFRVRFFQTTAVCKNDVITVQTPAFAESVTEGDVR-WEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAETPAPAHKAEPAAPAAPPPPAAPVLTQMPPVPSPS-------QPPSSKPVSAIKPTAA----PPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36957-1", "uniprot_id": "ODO2_HUMAN", "id": "P36957-1", "name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "aln": "MLSRSRCVSRAFSRSL--SAFQKGNCPLGRRSLPGVSLCQGPG----YPNSRKVVINN-SVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPS-------QPPSGKPVSAVKPTVA----PPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGQ1-1", "uniprot_id": "Q9VGQ1_DROME", "id": "Q9VGQ1-1", "name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "aln": "MTGIISIVTRRLPQTLGMRALRSNEVKRCIRQYSRLVACAAQQQQLLRQDGSNRCQEATRLLTWQGIHTTSSLWS-EQTVNVPPFADSIAEGDIK-FTCKVGDSFAADEAVMEIETDKTTVAVPAPFSGTLTDILVKDGDTVKPGQALFKIKPGAAPAKAAAPAAAPAPAAPKAAPAPAAAPKPAPPPPAAGAPKPPPPPPPKAAPRPPPPAPVAALKPAVAQVKVPPADGSRQILGTRSEQRVKMNRMRLKIAARLKDAQNTCAMLTTFNEVDMSYAMDFRKQNLDAFTKKYGIKFGFMSIFAKASAYALQDQPVVNAVIDGT--DIVYRDYVDISVAVATPRGLVVPVIRNVEGMNYADIEIALAGLADKARRDAITVEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAVKGEVKIRPMMYIALTYDHRIIDGREAVLFLRKIKAAVENPAIIVAGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19262-1", "uniprot_id": "ODO2_YEAST", "id": "P19262-1", "name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "aln": "MLSRATRTAAAKSLVKS-KVARNVMAASFVKRHASTSLFKQAN---KVESLGSIYLSGKKISVAANPFSITSNRFKSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKLNFKPEDTVTVGEELAQVEPGEAPAEGSGESKPEPTEQAEPSQGVAARENSSEETASKKEAAPKKEAAPKK--EVTEPKKADQPKKTVSKAQEPPVASNSFTPFPRTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGAIEGD--QIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKMLLW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .: . . :. : . . . . : : : :::.*.:*:*::**.:: : *** . ** : ***** : * :* .* : : . ..* * * :. *.. : : . .. ** . : . * . . . * :.: ** *:* * ****** :** ***::***.* ******:*** ::* : : ** . *:***. * **.: * :: *.**..*:. ::***** *********:***.**:**.* :. *** : *..*** . :::*** *************** ******.**:*:**:*.: :**::: *:: *****:*******::****** **:.:* :*:* :: ", "identical_positions": 156, "similar_positions": 115, "identity": "33.05%" }, { "cls_id": "homologset.agr.SGD:S000002558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17431-1", "uniprot_id": "TISB_RAT", "id": "P17431-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAG-----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APTLSSRDSRFRDRSFSEGGER---LLPTQKQPGSG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERR-ALAGGR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23950-1", "uniprot_id": "TISB_MOUSE", "id": "P23950-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAG-----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APSLSSRDSRFRDRSFSEGGER---LLPTQKQPGSG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERR-ALAGGR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07352-1", "uniprot_id": "TISB_HUMAN", "id": "Q07352-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAG-----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APALSSRDSRFRDRSFSEGGER---LLPTQKQPGGG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERR-ALAGAR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47974-1", "uniprot_id": "TISD_HUMAN", "id": "P47974-1", "name": "mRNA decay activator protein ZFP36L2", "aln": "MSTTLLSA--FYDVDFLCKTEKSLANLNLNN--------MLDKKAVGTPVAAAPSSGFAPGFLRRHSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPSGHH--QPPGGLESPLLLD---SPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSASCANNAFAFG-PELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAP-PAQPPAPPSATLPAGAAAPPSPPFSFQLPRRLSDSP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG--RRLPIFSRLSISDD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHK9-1", "uniprot_id": "D3ZHK9_RAT", "id": "D3ZHK9-1", "name": "mRNA decay activator protein ZFP36", "aln": "MSTTLLSA--FYDIDFLCKTEKSLANLNLNN--------MLDKKAVGTPVAAAPSSSFTPGFLRRHSASNLHALAH--PSPGSCSPKFPGAPNGSSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHH--QPPGGLESPLLLD---SPTSRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDLLTPGAPCATCSTTSCANNAFTFG-PELSSLITPLAIQTHNFAA-AAAAYYRSQQQG-LAGLAPAPAQPPAAP---------APPSPPFGFQLPRRLSESP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG--RRLPIFSRLSISDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22893-1", "uniprot_id": "TTP_MOUSE", "id": "P22893-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLQSMSHDL--SSDHGGTESL--------GGLWNINS-DSIPSG---------------------------VTSRLTGRSTSLVEGR-----------------------SCGWVPPPPGFAPLAPRPGPELS-------PSPTSPTATPTTSSRYKTELCRTYSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPTEDLALPGQPH-----------------------VLRQSISFSGLPSGRRSSPPPPGFSGPSLSSCSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPVTRRDPNQACCPSCRRSTTPST------------------IWGPLGGLAR---------------------------------SPSAHSLGSDP---DDYASSGSSLGGSDSPVFEAGVFGPPQTPAPPRRLPIFNRISVSE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47973-1", "uniprot_id": "TTP_RAT", "id": "P47973-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLMSMSHDL--SPDHGGTESS--------GGLWNINSSDSIPSG---------------------------VTSRLTGRSTSLVEGR-----------------------SCSWVPPPPGFAPLAPRPGPELS-------PSPTSPTATPTTSSRYKTELCRTYSESGRCRYGAKCQFAHGPGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPTEDLALPGQPH-----------------------VLRQSISFSGLPSGRRTSPPPPGFSGPSLSSCSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPVSRRDPTPACCPSCRRSTTPST------------------IWGPLGGLAR---------------------------------SPSAHSLGSDP---DDYASSGSSLGGSDSPVFEAGVFGPPQPPAPPRRLPIFNRISVSE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26651-1", "uniprot_id": "TTP_HUMAN", "id": "P26651-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWG---SSGPWSLSPSDSSPSG---------------------------VTSRLPGRSTSLVEGR-----------------------SCGWVPPPPGFAPLAPRLGPELS-------PSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPP-----------------------VLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRR-ATPIS------------------VWGPLGGLVR---------------------------------TPSVQSLGSDP---DEYASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCY5-1", "uniprot_id": "A0A8M1NCY5_DANRE", "id": "A0A8M1NCY5-1", "name": "mRNA decay activator protein ZFP36", "aln": "-MSDTFGESLMRNFYNLGLDDSFPNLSSSSDRL---IDDCWPVDSWSDRAPS--------------------------------KPQFPIKADRS------------------------MSLNDSFSRMKPHDVP-------------PPPGFPPLATLPSNRYKTELCRSFQEHGSCKYGAKCQFAHGENELRGLYRHPKYKTQACRTFYQFGYCPYGSRCHFIHEEKSSLSEQNPRQ------------------------LRQSVSFAGFTRSSS---PPSSYESLSFTR----APSVSPPP--------------------------------------------------EEILSP--VFSDSSRDMFSFSRHSSGDIHNSALFAPET------------------RSRCVCGHGN-------------------------NFPVSGGGLYIKVELKKAPLQRFSSEDSLSDRESYSSTGSSSGSESPTFDGSTGKRLSVFARMSVSD-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47980-1", "uniprot_id": "TIS11_DROME", "id": "P47980-1", "name": "Protein TIS11", "aln": "MSADILQKSREQDDSHYFERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQP---------------------AVASLVTITENLGNMNLHRKLERT-------QSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQS--QQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTG-----------------------------------SDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHG-----------------------PATPPESPNVPISPVHTPPPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47976-1", "uniprot_id": "CTH1_YEAST", "id": "P47976-1", "name": "mRNA decay factor CTH1", "aln": "MMPNVAPNSYYLNIPNANSTSTTTSSIFSDLN------KEYESKIKEIEEYY-------------------------------IKTLLNENTDND------------------------DSSSSEGHNINETDILSEYSPR-----PSPWLPSKPNCYHPLGDFKDLIISDSRPTNTLPINNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLPLTAENLQKLSQVDSQSTG------------------------LPYTLPIQKTTKLEP--CRRAPLQLPQLVNKTLYKTELC----------------------------------------------------ESFTIKGYCKYGNKCQFAHGLNELKFKKKSNNYRTKPCIN-------------------WSKLGYCPYG-----------------------KRCCFKHGDDKDVEIYQNANDGRSKDTALTPLPTSLAPSNNDNITNLSKPRNLHTSVKALQRMTW-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :* : . . :. * :: * :: . ..:. : : . : . : . * . . : . : : *:: ", "identical_positions": 5, "similar_positions": 33, "identity": "0.95%" }, { "cls_id": "homologset.agr.SGD:S000002559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99ND9-1", "uniprot_id": "RWDD1_RAT", "id": "Q99ND9-1", "name": "RWD domain-containing protein 1", "aln": "MT-DYGEEQRNELEALESIYPDSFTVLSEN-PPS-FTITVTSEAGENDET------VQTTLKFTYSEKYPDEAPLYEIFSQE-----NLEDN-------------------------------DVSDILKLLALQAEEN--LGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKKLFHGTPVTIENFLSWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGN---NVEVDESLFQEMDDLELEDGEDDPDYNPVAPGSDSSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQK7-1", "uniprot_id": "RWDD1_MOUSE", "id": "Q9CQK7-1", "name": "RWD domain-containing protein 1", "aln": "MT-DYGEEQRNELEALESIYPDSFTVLSES-PPS-FTITVTSEAGENDET------VQTTLKFTYSEKYPDETPLYEIFSQE-----NLEDN-------------------------------DVSDILKLLALQAEEN--LGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKKLFHGTPVTIENFLSWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGN---NVEVDESLFQEMDDLELEDGEDDPDYNPVAPGSDSSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H446-1", "uniprot_id": "RWDD1_HUMAN", "id": "Q9H446-1", "name": "RWD domain-containing protein 1", "aln": "MT-DYGEEQRNELEALESIYPDSFTVLSEN-PPS-FTITVTSEAGENDET------VQTTLKFTYSEKYPDEAPLYEIFSQE-----NLEDN-------------------------------DVSDILKLLALQAEEN--LGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGN---NVEVDESLFQEMDDLELEDDEDDPDYNPADPESDSAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCB9-1", "uniprot_id": "Q9VCB9_DROME", "id": "Q9VCB9-1", "name": "RWD domain-containing protein", "aln": "MSRNYKEDQTNEVEALDSIYCGDMEILATE-PHHKFQIPIATEEYSSEEPEKG---LACKLVFTFTATYPDGAPVVEIEEPE-----NFEDM-------------------------------FETRLLEHLQKTIEEN--LGMEMIFSLVSSAQEWLNERWDEHKFHQEELREQKLREIEEEERKKFEGTRVTVESFLKWKLEFEESTGIAAK---REKNNVSK-KQTGRELFMCDNTLNDSDIKFLLEAGENIENVKIDETLFQDIGELDLDD-DDDEDWVPGADDDDD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03768-1", "uniprot_id": "GIR2_YEAST", "id": "Q03768-1", "name": "Protein GIR2", "aln": "--MDYKEEQKQELEVLESIYPDELRIINDEYPKIKFEVAIKLELDTGDSTSVLTKEHTIIAEFKLPENYPDEPCLISLEAQEVALNDNEEDNEEDEDEVEYDDHGNKVLKKFENLPDLISFKGYLPELTVQLESQIETDMLLGMQMCFALISSIKERCEQWYSEQLNKLEKQYELEAQEREKKEQAKFHGTKVTRESYLEWRSKFRQELKLDERDQVRRMK-AHHGKLTGKQMFEQG----------VVGTGD----------EYMEEDDASVDDVAKGLAKTEIANQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:* :*:*.*:*** ..: :: . * * :.: * .:.. *. . .*** . : .: * * ** . : * * : *** * *:*::: :* :: .: : *: : : :* *: *: *.** ** *.:*.*: :* . : :. : . : * :*:::* . : :*: : : .: .::* .. ", "identical_positions": 47, "similar_positions": 75, "identity": "16.04%" }, { "cls_id": "homologset.agr.SGD:S000002562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J2A2-1", "uniprot_id": "PAL4C_HUMAN", "id": "A0A0B4J2A2-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4C", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B767-1", "uniprot_id": "PAL4H_HUMAN", "id": "A0A075B767-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DN37-1", "uniprot_id": "PAL4G_HUMAN", "id": "P0DN37-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4G", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVIFFDITVDGKPLGRISIKQFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTHPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B759-1", "uniprot_id": "PAL4E_HUMAN", "id": "A0A075B759-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DN26-1", "uniprot_id": "PAL4F_HUMAN", "id": "P0DN26-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4F", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F5H284-1", "uniprot_id": "PAL4D_HUMAN", "id": "F5H284-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y536-1", "uniprot_id": "PAL4A_HUMAN", "id": "Q9Y536-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4A", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTS--------------------KKITIADCGQF---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17742-1", "uniprot_id": "PPIA_MOUSE", "id": "P17742-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTS--------------------KKITISDCGQL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10111-1", "uniprot_id": "PPIA_RAT", "id": "P10111-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NPTVFFDITADGEPLGRVCFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMSIVEAMERFGSRNGKTS--------------------KKITISDCGQL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGK-------VKEDHHLRLWT--------------TLISLTCGHFTHQTIPSVAQESTPTPSARNTL----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCZ9-1", "uniprot_id": "M0RCZ9_RAT", "id": "M0RCZ9-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NLTMFFNITADGEPLGRVSLELFADKVPRTAENFRSLTTGEKGFGYKGSSFHRIIPGFMCQGGKVTCHNGTGGKSIYGEKFENDSFILKHTGPGILSMANAGPNTNGSQFFICTAKTERLDGKCVVFGKGRGGTNIVEAMEHFGSRNGKTSKKITISDCGQLLVSLICGHFTHQTIPSVAQESAPTPSARNTL----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62937-1", "uniprot_id": "PPIA_HUMAN", "id": "P62937-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "------------------------------------------------------------------------------------------------------------MV------------------------------NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTS--------------------KKITIADCGQLE--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29117-1", "uniprot_id": "PPIF_RAT", "id": "P29117-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "------------------------------------------------------------------MLALRCGPRLLGLLSGPRSAPLLLSTTRTCSDG-GARGANSSSQ------------------------------NPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTS--------------------KKIVITDCGQLS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KR7-1", "uniprot_id": "PPIF_MOUSE", "id": "Q99KR7-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "------------------------------------------------------------------MLALRCGPRLLGLLSGPRSAPLLLSATRTCSDG-GARGANSSSG------------------------------NPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGRSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTS--------------------KKIVITDCGQLS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30405-1", "uniprot_id": "PPIF_HUMAN", "id": "P30405-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "------------------------------------------------------------------MLALRCGSRWLGLLSVPRSVPLRLPAARACSKGSGDPSSSSSSG------------------------------NPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRTS--------------------KKIVITDCGQLS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N864-1", "uniprot_id": "A0A8M1N864_DANRE", "id": "A0A8M1N864-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "------------------------------------------------------------------MLILGN---RLKLCSVAFTAARLYSTG------------VQANN------------------------------NPVVFFDIAADNQPLGRVTFELNADVVPKTAENFRALCTGEHGFGYKGSIFHRVIPQFMCQGGDFTNHNGTGGKSIYGPRFPDENFKLKHTGPGILSMANAGVNTNGSQFFICTAKTEWLDGRHVVFGSVKEGMDVVRKVEALGSRSGRTA--------------------QRISITDCGELK--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATK--------------------ARIVVAKSGEL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMST------------------------------LPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTS--------------------KKIIVANSGSL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "------------------------------------------------------------------------------------------------------------MA------------------------------RPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLDVIKKVEGFGSSSGKTS--------------------AKIIIADCGQL---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QZH3-1", "uniprot_id": "PPIE_MOUSE", "id": "Q9QZH3-1", "name": "Peptidyl-prolyl cis-trans isomerase E", "aln": "MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGPEPPKAEAQEGEP--TAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPK--------------------QKVMIADCGEYM--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L608-1", "uniprot_id": "A0ABK0L608_RAT", "id": "A0ABK0L608-1", "name": "Peptidyl-prolyl cis-trans isomerase E", "aln": "MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGPEPPKAEAPEGEP--AAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEITDGLDVLRQIEAQGSKDGKPK--------------------QKWSCCSRGPHRTLASLEETNHERLSGAWCCLSKQTSQARIQAVPWKTEVHKLRPTEDELFNAWKSSCRHGDSYPAQHKAEAGERVGQRLRGTKASLLRVLFLRDLEKLLLGQARVHLPYQLCSLCPIIRLDPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNP9-1", "uniprot_id": "PPIE_HUMAN", "id": "Q9UNP9-1", "name": "Peptidyl-prolyl cis-trans isomerase E", "aln": "MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGSEPPKAETQEGEP--IAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPK--------------------QKVIIADCGEYV--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3G3-1", "uniprot_id": "PPIE_DROME", "id": "Q9V3G3-1", "name": "Peptidyl-prolyl cis-trans isomerase E", "aln": "MSNDKRTIYVGGLADEVTERLLNNAFIPFGDIADIQMPADYESQRHRGFAFIEYEQSEDAAAAIDNMNDSELCGRTIRVNLAKPVRVKEDSFKPIWADDDWLQKHAGATLQPEGE---PEAEKVETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYGYKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPS--------------------QKIVIYSCGELK--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::: ... **: : * : ****** * * : *: : *. ***:** ** *.*..* ***..:**** :* ::.: :* * ***.*:* ******:*: **.: *.** :. . : . . ", "identical_positions": 50, "similar_positions": 41, "identity": "11.24%" }, { "cls_id": "homologset.agr.SGD:S000002566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JV99-1", "uniprot_id": "A0A0G2JV99_RAT", "id": "A0A0G2JV99-1", "name": "Germinal-center associated nuclear protein", "aln": "-----------MNPVNPFSGQQPGAFAVSSSATGTFQTKSPFRFGQPSLFGQNNQAS-KSLGFSQVPSFATPSGGSHSSSLPAFGLTQTSSVGLFSGLESTPSFAATSGPSSSSVPGNTAFSFKSASSVGVFSSGPTFGPETGDVAGSGFRKTEFKFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPVSSGSGGLTPFSFPQVTNSSATSSSFIFSKPVTSN--TSAFAPALSNQNIEEEKRGPKSVFGGLNSSFSTFPMASPGSLGEPFPTNKTSIRQGGEEAISQVESHPALMKGLKRKEDQDRSPRRHCHEAAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESKKDSGFVESGESDHVAIPGGSQSTLVTSRLPAVNKEEETEGRDEKEDSLRGTSVRQSKR-SESTDSLGGMSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHKDMAIFWHKKKISPSKKPFSLKEKQLGEGEASQGIEDSPFQHSPLGKPIVRPATGSLLNKSSPVKKPGLLKIHQFEADPFDSGSEGSEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPG-----TDQVDHAAAVKEYSRSSADQEEPLPHELR-PSAVLSRTMDYLVTQIMDQKEGS-LRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTR--FHIHCAH-FMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVF-------CASEAEFQGYNVLLNLNKGDILREVQQFHPDVRNSPEVDF-------------------------AVQAFAALNSNN-----FVRFFKLVQSAS-----YLNACLLHCYFNQIRKDALRALNV--------------------------AYTVSTQRSTVFPLDGVVRMLLFRDCEEATSFLNYHGLTVA-----DGCVELNRSAFLEPEGLYKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISAQRSGGDSAGGGRGEEVEAEVDVPPLAVLPQ--LPPAPSAT-----PVPHVQPLTQAVTPSLFQASTQPEVLLPKPVPVYSDSDLVQVVDELIQEALQVDCEEVSSAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRVEEEKRRAEEERLKQERELMLTQLSKGLAAELTELTVTECVWETCSQELKSAVETDQKVRVARCCEAVCTHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWRGAVAARKKLRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGISCTRLRRLRNKTAHQMKVQHFHQQLLSNAAWAPLDLPSFVAEHLPVKQKRIFWKLVLVLPDGEEQTPESPGRILENWLKVKFTGDGSLVDDTRDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVARGTLSDSALDAVETRKDLLGASGLMLLLPPKVKSEDVAEEDLYWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSTGKGVEDGLMLQDLISAKLISDYIVVEIPDFVNDLHGTVKVSGAVQWLISRCPQALDLCCQT---LIQYVEDGISREFSGRFFHDRRERRLGSLASQEPSAIIELFNSVLQFLASVVSSEQLGDISWPVTEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPAALWLPVCSMVIQYTSQIPSSCRTQPVLRSQVESLLCRTYQKWKSKSLCPGQQSGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLDALSEDGQICVYFFKNRLRKYTVPLSWEQARMQTQRELQLSQGCSGIKSFHP-TSSFPTPLLHGRHKGKKKEDGGREG-SLSTEDLLRGASAEELLAQCLNNSLLEEREENKRFEDQLQQWLSRDSQAFTESARLPLYLPQTLVSYPDAIKTQTKVKTSTSPQNAGTGDHVRFSEASDTSLTEKLKHLERLIQSSRAEEAASELHLSALLDMVDI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUU9-1", "uniprot_id": "GANP_MOUSE", "id": "Q9WUU9-1", "name": "Germinal-center associated nuclear protein", "aln": "-----------MHPVNPFGGQQPSAFAVSSSTTGTYQTKSPFRFGQPSLFGQNSTPS-KSLAFSQVPSFATPSGGSHSSSLPAFGLTQTSSVGLFSSLESTPSFAATS---SSSVPGNTAFSFKSTSSVGVFPSGATFGPETGEVAGSGFRKTEFKFKPLENAVFKPIPGPESEPEKTQSQISSGFFTFSHPVGSGSGGLTPFSFPQVTNSSVTSSSFIFSKPVTSN--TPAFASPLSNQNVEEEKRVSTSAFGSSNSSFSTFPTASPGSLGEPFPANKPSLRQGCEEAISQVEPLPTLMKGLKRKEDQDRSPRRHCHEAAEDPDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESK-ESGFAEPGESDHAAVPGGSQSTMVPSRLPAVTKEEE-ESRDEKEDSLRGKSVRQSKRREEWIYSLGGVSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHKDVVIFWHKKKISPSKKLFPLKEK-LGESEASQGIEDSPFQHSPLSKPIVRPAAGSLLSKSSPVKKPSLLKMHQFEADPFDSGSEGSEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPG-----TDQVDHAAAVKEYSRSSADQEEPLPHELR-PSAVLSRTMDYLVTQIMDQKEGS-LRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTR--FHIHCAH-FMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVF-------CASEAEFQGYNVLLNLNKGDILREVQQFHPDVRNSPEVNF-------------------------AVQAFAALNSNN-----FVRFFKLVQSAS-----YLNACLLHCYFNQIRKDALRALNV--------------------------AYTVSTQRSTVFPLDGVVRMLLFRDSEEATNFLNYHGLTVA-----DGCVELNRSAFLEPEGLCKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISTQRAGGDPAGGGRGEDCEAEVDVPTLAVLPQ--PPPASSAT-----PALHVQPLAPAAAPSLLQASTQPEVLLPKPAPVYSDSDLVQVVDELIQEALQVDCEEVSSAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRLEEEKQRAEEERLKQERELMLTQLSEGLAAELTELTVTECVWETCSQELQSAVEIDQKVRVARCCEAVCAHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWREAVAARKKFRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGVSCTRLRRLRNKTAHQIKVQHFHQQLLRNAAWAPLDLPSIVSEHLPMKQKRRFWKLVLVLPDVEEQTPESPGRILENWLKVKFTGDDSMVGDIGDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVAHGTLSDSALDAVETQKDLLGTSGLMLLLPPKVKSEEVAEEELSWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSAGRAVEDGLMLQDLVSAKLISDYIVVEIPDSVNDLQGTVKVSGAVQWLISRCPQALDLCCQT---LVQYVEDGISREFSRRFFHDRRERRLASLPSQEPSTIIELFNSVLQFLASVVSSEQLCDISWPVMEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPGAPWLPVCSMVIQYTSQIPSSSQTQPVLQSQVENLLCRTYQKWKNKSLSPGQELGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLEALSEDGQICVYFFKNLLRKYHVPLSWEQARMQTQRELQLSHGRSGMRSIHPPTSTFPTPLLHVHQKGKKKEESGREG-SLSTEDLLRGASAEELLAQSLSSSLLEEKEENKRFEDQLQQWLSQDSQAFTESTRLPLYLPQTLVSFPDSIKTQTMVKTSTSPQNSGTGKQLRFSEASGSSLTEKLKLLERLIQSSRAEEAASELHLSALLEMVDM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60318-1", "uniprot_id": "GANP_HUMAN", "id": "O60318-1", "name": "Germinal-center associated nuclear protein", "aln": "-----------MNPTNPFSGQQPSAFSASSSNVGTLPSKPPFRFGQPSLFGQNSTLSGKSSGFSQVSSFPASSGVSHSSSVQTLGFTQTSSVGPFSGLEHTSTFVATSGPSSSSVLGNTGFSFKSPTSVGAFPSTSAFGQEAGEIVNSGFGKTEFSFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPISSAPGGLAPFSFPQVTSSSATTSNFTFSKPVSSNNSLSAFTPALSNQNVEEEKRGPKSIFGSSNNSFSSFPVSS-AVLGEPFQASKAGVRQGCEEAVSQVEPLPSLMKGLKRKEDQDRSPRRHGHEPAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQDVFKSNKEVGRLGNKEAKKETGFVESAESDHMAIPGGNQSVLAPSRIPGVNKEEETESREKKEDSLRGTPARQSNR-SESTDSLGGLSPSEVTAIQCKNIPDYLNDRTILENHFGKIAKVQRIFTRRSKKLAVVHFFDHASAALARKKGKSLHKDMAIFWHRKKISPNKKPFSLKEKKPGDGEVSPSTEDAPFQHSPLGKAAGRTGASSLLNKSSPVKKPSLLKAHQFEGDSFDSASEGSEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPG-----TDQVDHAAAVKEYSRSSADQEEPLPHELR-PLPVLSRTMDYLVTQIMDQKEGS-LRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTR--FHIHCAH-FMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVF-------CASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVKF-------------------------AVQAFAALNSNN-----FVRFFKLVQSAS-----YLNACLLHCYFSQIRKDALRALNF--------------------------AYTVSTQRSTIFPLDGVVRMLLFRDCEEATDFLTCHGLTVS-----DGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRGEECGVEPDAP-LSSLPQSLPAPAPSPV-----PLPPVLALTPSVAPSLFQLSVQPEPPPPEPVPMYSDEDLAQVVDELIQEALQRDCEEVGSAGAAYAAAALGVSNAAMEDLLTAATTGILRHIAAEEVSKERERREQERQRAEEERLKQERELVLSELSQGLAVELMERVMMEFVRETCSQELKNAVETDQRVRVARCCEDVCAHLVDLFLVEEIFQTAKETLQELQCFCKYLQRWREAVTARKKLRRQMRAFPAAPCCVDVSDRLRALAPSAECPIAEENLARGLLDLGHAGRLGISCTRLRRLRNKTAHQMKVQHFYQQLLSDVAWASLDLPSLVAEHLPGRQEHVFWKLVLVLPDVEEQSPESCGRILANWLKVKFMGDEGSVDDTSSDAGGIQTLSLFNSLSSKGDQMISVNVCIKVAHGALSDGAIDAVETQKDLLGASGLMLLLPPKMKSEDMAEEDVYWLSALLQLKQLLQAKPFQPALPLVVLVPSPGGDAVEKEVEDGLMLQDLVSAKLISDYTVTEIPDTINDLQGSTKVLQAVQWLVSHCPHSLDLCCQT---LIQYVEDGIGHEFSGRFFHDRRERRLGGLASQEPGAIIELFNSVLQFLASVVSSEQLCDLSWPVTEFAEAGGSRLLPHLHWNAPEHLAWLKQAVLGFQLPQMDLPPLGAPWLPVCSMVVQYASQIPSSRQTQPVLQSQVENLLHRTYCRWKSKSPSPVHGAGPSVMEIPWDDLIALCINHKLRDWTPPRLPVTSEALSEDGQICVYFFKNDLKKYDVPLSWEQARLQTQKELQLREGRLAIKPFHPSANNFPIPLLHMHRNWKRSTECAQEGRIPSTEDLMRGASAEELLAQCLSSSLLLEKEENKRFEDQLQQWLSEDSGAFTDLTSLPLYLPQTLVSLSHTIEPVMKTSVTTSPQSDMMREQLQLSEATGTCLGERLKHLERLIRSSREEEVASELHLSALLDMVDI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H687-1", "uniprot_id": "SAC31_MOUSE", "id": "A6H687-1", "name": "SAC3 domain-containing protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRFKGENRSQARWIMGGVSKGRGSGKSRKPRQAAFG-QTGARVCPSSPQQDA--------------------------------------------------------------------VPRFRWPGDAECASSTHTPTMSGCKLPMGLCPDMCPAAERARRERERRLHRLEVEPGGRGN-APRADPKRTVKEYSRPAAGKPRPPPSLLR-PPPVLLATVRYLAGEVAGRGDVS-CAEVASFVADRLRAVRLDLSLQGVDDADAATVLEAALA--TLLAVVARVRPEETRGAADPVLLQTQVQEGFGSLRRCYARGKGP----------YPRQAAFQGLFLLYNLGSVEALQEVLQLPAALRACPPLQA-------------------------ALAVDAAFREDN-----HARLFRLLRTLP-----YLQSCAVQEHIGYARRKALARL----------------------------SRALSTPKGQTLPLDFIEHFLALDGLQEARDLCQAHGLTLD-----KDRVVFLRGQYSE---------------------------EGLPPPGAYHILVGNKLQGHTLEDVVMAEEG--DIHRPGSAA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT97-1", "uniprot_id": "D3ZT97_RAT", "id": "D3ZT97-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRFKGENRSQARWIMGGVSKGRRSRKSRKPGEEGWASQTGSQACSPSPRQDA--------------------------------------------------------------------VPRFRWPSDAECASSTHSPAMSDYKLPMGLCPDMCPAAERARRERERRLHRLEVEPGGCGN-APRADPRRTVKEYSRPAAGKPRPPPSLLR-PPPVLLATVRYLAGEVADRTDVS-CAEVASFVADRLRAVRLDLSLQGVDDAEAAAVLEPALA--TLLVVVARMRPEETRGVADPVLLQTQVQEGFGSLRRCYARGKAP----------HPRQAAFQGLFLLYNLGSVEALQEVLQLPAALRACPPLQT-------------------------ALAVDSAFREDN-----YARLFRLLRTLP-----YLQSCAVQEHIGYARRKALSRL----------------------------SRALSTPRGQTLPLDFIVHLLALDGLQEAQDLCQAHGLTLD-----KDRVIFLRGQYSE---------------------------EGLPSPGTCHLLVGSKLQGHTLEEVVMAEEEK-DIHRPGSPT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NKF1-1", "uniprot_id": "SAC31_HUMAN", "id": "A6NKF1-1", "name": "SAC3 domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGRRAQTGSAPPR------------PAAPHPRPASRA--------------------------------------------------------------------FPQHCRPRDAERPPSPRSPLMPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPGCRQD-PPRADPQRAVKEYSRPAAGKPRPPPSQLR-PPSVLLATVRYLAGEVAESADIA-RAEVASFVADRLRAVLLDLALQGAGDAEAAVVLEAALA--TLLTVVARLGPDAARGPADPVLLQAQVQEGFGSLRRCYARGAGP----------HPRQPAFQGLFLLYNLGSVEALHEVLQLPAALRACPPLRK-------------------------ALAVDAAFREGN-----AARLFRLLQTLP-----YLPSCAVQCHVGHARREALARF----------------------------ARAFSTPKGQTLPLGFMVNLLALDGLREARDLCQAHGLPLDG----EERVVFLRGRYVE---------------------------EGLPPASTCKVLVESKLRGRTLEEVVMAEEEDEGTDRPGSPA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8D7-1", "uniprot_id": "A0AB13A8D7_DANRE", "id": "A0AB13A8D7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS--IAWSHSRRGR------------------GPRQKE--------------------------------------------------------------------QTGVIQDQKAEAS------------VPHGSCMTMCPAYELRQREAQSRLHRFEMLPGTEQDRLPRADISRAVKEYSRPAAGKDSTRASDLR-PPSVLLKTVSYLVDEVATSSTFQPWTEVYSFVFDRLRSVRQDMIIQRVSGPDCVAVLEKSVR--FLLYSSYRLCG-QPLQLYDPRINDTHLQESLSWLLESYSEGK------------HQHQEEFQALALLYNLGSAQAVQHVLALPERIRSSLAVRL-------------------------ALEVSRAHMERN-----PVRLLRLAKKLD-----FMQVCAVHRHLLPCRRDLLLLY----------------------------SHGHSS-RNYRYPLQRLAQLLCLK-EALAVELCTVYSVKVT-----GDCVNFSKSSFTE---------------------------ASS-----------ADLQCRHMHEPLDHEHWNGSSGSLIHSCA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSZ4-1", "uniprot_id": "Q9VSZ4_DROME", "id": "Q9VSZ4-1", "name": "SAC3/GANP/THP3 conserved domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQVRGSCESFCPDGEAKMRIREKLLHYFELKNG------QKNKPGVLVKEFTRSAADVKMPMPKEMR-TEAALTKTVEYLLKDIILDTRKP-YNVAYDFIFDRLRAVRREIVIQMYDASQKICLLEPIVM--FLAYSRY-RLCEEPIEKFDLKICNQHLQECLTGVLCCYEELEDLESSREPTVRELERRCFIESLYQLFNLGSPESFTRALTLPDYVRRDATFKL-------------------------CFGICLAFQQGN-----LYRVLMGVPQLP-----HILCAVAAAKLQVIRRSLLQIFT-----------------------------HAYNNKQLTVPVPYLLRLLLFDGPTGLQDQCRHYNISLTAD---RKAVQFNKTDFNH---------------------------NAEVFTPQHERFVESKLKRIYIPEVLLLKKFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U3V9-2", "uniprot_id": "XMAS_DROME", "id": "Q9U3V9-2", "name": "Protein xmas", "aln": "MAEPRPGGYNYKTLLCRNIPELFLDKYVARSHFGRFGTLVNFVLRPRRMTCTVSYASEDEAARALLDGASFQGHLFDISYADNETAPAQKTEEWVDPDIQAELSALQSGWRNEYGSGKPIKKPQNGSSGSGGSSMLPAIPVGPATAPVSRDRTPAQLRDLENMMRRPAHTSEEKFSVLDARDKLLRLNRTQHKLSGATQGHCADMCPEKERVLREFQRQVAYYELQPGSDELICHERALKQYSRSSADQETPLPHELRNETALHMTMSYLMHEIMDISERQDPQSHMGDWFHFVWDRTRSIRKEITQQELCSLGAVKLVEQCARFHIHCAARLVDADPSVFDSKINAENLTKCLQTLKYMYHDLRIKGVPCPKEAEFRGYIVLLNLADANFLWDIGQLPAELQSCPEVRQAIQFYLALQDTNFVRFFQLLADKDTSYLSACILVNYFTRLRVLGLHRLIQAYRSPRKDE--VSSLPLSYIAELLSFASEQEAADFVQHYGLQINEAGRVVLSRMHTVETEYKLPRQYELVEVKRVKSVGEVVSGEPLPPRDLYLNHRPHNSFDDYGMLKSIAWTAKDQLAGMQQEEMQPQMPSQPPAVSKHSDTLFKVPMQPDGTAAGFGVFAAAAVPPASSIDGFSFVLPKSRAQEFQEQAPATQQRRAQEEAKHQALQVAIAAAKKREAELMAIHEAKVAEAERVRQQKLRERQEQQRRQQQELEEQRQREQEKLQLEKERQLKLEQLFFVQQQEREAHKQTRTLELYQEIFQDTLAEICQSEFMSHSRACRSYESMLDSITRDLVERQMEQSIYELGVMRVCIRRWRKYRRTQ---QEKDTLFNQLPLSFGAENPEGVVNKRSMEDSLRLSRRYRLGEPCDYGKLLAGLEEHSWLKLDLWHVLDKCLPVAQPG-----ARRFYKLLISLSGGQEGLQLNCDLDRGLLQQPQSPDARFVDGGYIRGFSQGIGLSVMKIRDDDHDWKATDLAEANGIICLIGLDDIRLLPDRLKPLLQASRCHDVAVIVQHPANTAFVQPDIPLQELCLRSFNIFRLRKSGNNRQRLMIALESAVKFLAKATERKRVGHLHQVETREYLLVNLGSELFRRLKYAAEHDTAIRSDTQLNPQRCVDLFNEAVHRLQLVAGEDLSDWPQFPEELRVFVQPLPIESSLNTNRLEHFEPGWHLPERRQRIVQLLERCKLPKMPVLPRSSSLAEAQCQWVLDYAQISQQEDCVEQIALQAIKILQYDTDDYLNFVEYLAGERMQYILRQERNPPQGIVYNTKTLKRRFLSAWYYEFREPQIYEPVPAEENAQMLEKQPSSQAEVQQLDFDEITSKAEAVLKRFHQRQDERHTLRELNRSHKSRKRRDASDHKHAMSSLVSALKAARSDYQGKSSAVCRLVAQMVEADQVKYQWTPNLTSLIDRKDASTRHQWRPHVNHSTRHARKLPVQSISFLSRCLAKKGEHAGLTSCVLSVKTRYAPKTLHGRELLIWRQSSMRPLLLPSSNLWTGVLSKRHYVPRLRPAEEDEEVERRAVPQLRITKEQSEEEEHQLQRRKDGSRLRNECSEFYLPMGEQDYSEREEENRGHRQAYVPSELMTPELATKWQTTSVTDRDRQLLNLEQQMKTQPSVRMTTQTWFSGNHRRYRSRRSGAKRYHVVSELEGWRRSSNHQPVPVFQGQPGEQEHLRHASHKASARSMPDGQERCQMVWEQKKRSPWHRTEVTNSNKVRMPRIRAAKSAVMMAQEARNKHHRLITKKLVYRPRRTVNAVQAEETEDQDTHHRHHGGGQKMSKRAPERALLKQHLADLLAVSKPEDSFRIGYQPNAPTRQLLEQGKCYVSLRREQFIHLHPVRPNSLILAVNLEVKESPRQPVTTLHRRDGAKRPRLVEDVVKPSLITVIRQSAATWDHNGRKVPAKKSNLVGMPSKEHAYQRRLVRNTSTLEAIVKAQAKPRSEPKSPSSATDYHRVASQKLPHVTSKADISKAADPFKDLDKPRIKEKEVASSWKQAYVVRSKMYDAITPYRRRAYPGKKCITKDKTDGYFLAKRSSAAAAGSSKKVKPPKQPVVSPKVQVPSVLHKKKSRESLGPQTTKTGKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46674-1", "uniprot_id": "SAC3_YEAST", "id": "P46674-1", "name": "Nuclear mRNA export protein SAC3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTSFGSVVPSTNFNFFKGHGNNDNTSANSTVNNSNFFLNSNETKPSKNVFMVHSTSQKKSQQPLQNLSHSPSYTENKPDKKKKYMINDAKTIQLVGPLISSPDNLGFQKRSHKARELPRFLINQEPQLEKRAFVQDPWDKANQEKMISLEESIDDLNELYETLKKMRN---------------------------------------------------------TERSIMEEKGLVDKADSAKDLYDAIVFQGTCLDMCPTFERSRRNVEYTVYSYEKNQPN----DKKASRTKALKVFARPAAAAAPPLPSDVR-PPHILVKTLDYIVDNLLTTLPES-----EGFLWDRMRSIRQDFTYQNYSGPEAVDCNERIVR----IHLLILHIMVKSNVEFSLQQELEQLHKSLITLSEIYDDVRSSGGT-------CPNEAEFRAYALLSKIRDPQYDENIQRLPKHIFQDKLVQMALCFRRVISN---------------SAYTERGFVKTENCLNFYARFFQLMQSPS---LPLLMGFFLQMHLTDIRFYALRALS-----------------------------HTLNKKHKPIPFIYLENMLLFNNRQEIIEFCNYYSIEIIN----GDAADLKTLQHYSHKLS-----------------------ETQPLKKTYLTCLERRLQKTTYKGLINGGEDNLASSVYVKDPKKDRIPSIADQSFLMENFQNNYNEKLNQNSSVKPQINTSPKRVATRPNHFPFSQESKQLPQISQSHTLSTNPLLTPQVHGDLSEQKQQQIKTVTDGGSPFVFDQSAQNSTVEASKAHMISTTSNGAYDEKLSSEQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVNSSVISIVKREFSEANYRKDFIDTMTRELYDAFLHERLYLIYMDSRAELK--------------RNSTLKKKFFEKWQASYSQAKKNRILEEKKREEIKLVSHQLGVPGFKKSTCLFRTPYKGNVNSSFMLSSSDKNLIFSPVNDEFNKFATHLTKISKLWRPLEMQSIYYDNLTKKFPSNSLTPANLFIYAKDWTSLSNRWILSKFNLQTAQDSKKFSNN-----------------------------------------------------------IISSRIICIDDEYEPSDFSDLQLLIFNTGVTNPDIFDLEMKLKDDGEELIKLITGISLNTNICFSLLIIYWESAENTLSESTIKHLLKLNRISKNYSSVIERIDLMNLTEESPHKCLEDKLSEISHSYVYKLTERGKYDKTLRQKRSLAGIHSRSTQLQTTKDIDQKMKKMLEKEKNKYQQQIGER--------------------------------------------NTYAHLESHIDASPRSKKRKLPILLSTSHSSQFKTPLASRLNTSGSSTSPPLPSHLAMKFRKNSRVTSLHTVLPVSTPSHSNNIPAASFSGNNTTDIQSQQLIENQKSTSVYLNNVSERILGNQEICQTPINPVTPVLDGADQGKEDIPDSILELKILIDSVKKKVNND------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . : * * * .: *: :: * : :: : : : :. . : . : : . *. . . . * . :.: : : : ", "identical_positions": 7, "similar_positions": 36, "identity": "0.34%" }, { "cls_id": "homologset.agr.SGD:S000002570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P013-1", "uniprot_id": "CWC15_HUMAN", "id": "Q9P013-1", "name": "Spliceosome-associated protein CWC15 homolog", "aln": "MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRP---------TREHTTSSSVS------KKPRLD----------QIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQAN----------FKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJP2-1", "uniprot_id": "CWC15_RAT", "id": "Q5BJP2-1", "name": "Spliceosome-associated protein CWC15 homolog", "aln": "MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRP---------TREHTTSSSVS------KKPRLD----------QIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQAN----------FKVKRRWDDDVVFKNCAKGIDDQKKDKRFVNDTLRSEFHKKFMEKYIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHS9-1", "uniprot_id": "CWC15_MOUSE", "id": "Q9JHS9-1", "name": "Spliceosome-associated protein CWC15 homolog", "aln": "MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAARDKNRDRP---------TREHTTSSSVS------KKPRLD----------QIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQAN----------FKVKRRWDDDVVFKNCAKGIDDQKKDKRFVNDTLRSEFHKKFMEKYIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQU4-1", "uniprot_id": "CWC15_DANRE", "id": "Q6IQU4-1", "name": "Protein CWC15 homolog", "aln": "MTTAARPTFEPARGGRGKGEGDLSALSKQYSSRDLPGHTKIKYRQPTQDAPEEVRARDFRRELEERERAAVK--GRDRG---------AREHTTSSSSSSSSSSSKRPRLD----------QIPAANLDADDPLTDDEDDSGSDSDSDDDTAALLAELEKIKRERAEEQERKEREQKAEEERIRMENILSGNPLLNLAGQQQQQQQQQQQTQTKNTFSVKRRWDDDVVFKNCAKGVDESRKEKRFVNDTLRSEFHKKFMEKYVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3B6-1", "uniprot_id": "CWC15_DROME", "id": "Q9V3B6-1", "name": "Protein CWC15 homolog", "aln": "MTTAARPTFDPARGGSGRGEKDLSALSKQYSSRDLPGHTKLKYRETGQGTSDENRNRDFRKELEEREREARSGTGATSSSSGKALPSIVRKAIEANNAGGGSSAAKRSKPDAGQQQAQQAAQQQAANMDADEPLDNDSSDS--DSDSDDDDAALLAELQKIKQERLQETARRESEKKQEDERIRMENILSGNPLMNYEPGTAASAAG-RASGLGGDLKIKRRWDDDVVFKNCARSAPD--KKTHFVNDALRSDFHKKFMDKYIK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03772-1", "uniprot_id": "CWC15_YEAST", "id": "Q03772-1", "name": "Pre-mRNA-splicing factor CWC15", "aln": "MTTSHRPQLEARSG----AKAAAYTPTGIEHARLLPGHTTLKYRK-------------FKEEENLRANCAQEDRSNDKS-------------------------------------------LEEAVMNEEK-QDVVGSGNLQETRSEKDQKDSLQELLVTQKNKVEDKAELEGNEQLKGGNSSRRSWRKGTAFG----------------------------RHKVTKETNIKEHATKKSASGYINDMTKSEYHQEFLHKHVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ** ::. * .: : :* **.**.:***: *:.* : * . * . * :: :. . . : .:.* * ** :::: :: . * ::: : . .. .*..: ..*. :. : . . ::** :*::*::*:.*:::", "identical_positions": 32, "similar_positions": 65, "identity": "12.12%" }, { "cls_id": "homologset.agr.SGD:S000002571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PV2-1", "uniprot_id": "Q99PV2_RAT", "id": "Q99PV2-1", "name": "", "aln": "MAPPVTERGLKSVVWRKIKTTVFDD----CRKEG----------EWKIMLLDDFTTRLLSSCCKMTDLLEEGVTVIENIYK-NREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKAS--CSKSIRRCKEINISFIPHESQVYT-LDVPDAFYYCYSPDPSNAGRKEAVMEAMAEQIVTVCATLDENPGVRYKSKP----------------LDNASKLAQLVEKKLEDYYKIDENGLIKG--KTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP---IEKDTYKYKTDG----KEKEA--VLEEDDDLWVRVRHRHIAVVLEEIPKLMKEIS-STKKATE--GKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNK-FKLNIEKLCKTEQDLA-LGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGVNGTTEENLDRLIHNVKIE-DDSDMIRNWSHLG---------VPIVPPS---QQAKPPRKDRSAEETFQLSRWTPFIKDIMEDAIDN--RLDSKEWPYCSRC---------------PAVWNGSGAVS-ARQKPR-TNYLELDRKNGSR--LIIFVIGGITYSEMRCAYEVSQAHK-SCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFLKDE------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60770-1", "uniprot_id": "STXB3_MOUSE", "id": "Q60770-1", "name": "Syntaxin-binding protein 3", "aln": "MAPPVSERGLKSVVWRKIKTAVFDD----CRKEG----------EWKIMLLDEFTTKLLSSCCKMTDLLEEGITVIENIYK-NREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKAS--CSKSIRRCKEINISFIPQESQVYT-LDVPDAFYYCYSPDPSNASRKEVVMEAMAEQIVTVCATLDENPGVRYKSKP----------------LDNASKLAQLVEKKLEDYYKIDEKGLIKG--KTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP---IENDTYKYKTDG----KEKEA--VLEEDDDLWVRVRHRHIAVVLEEIPKLMKEIS-STKKATE--GKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNK-FKLNIEKLCKTEQDLA-LGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGINGTTEENLDRLIHNVKIE-DDSDMIRNWSHLG---------VPIVPPS---QQAKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDN--RLDSKEWPYCSRC---------------PAVWNGSGAVS-ARQKPR-TNYLELDRKNGSR--LIIFVIGGITYSEMRCAYEVSQAHK-SCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFKDE-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00186-1", "uniprot_id": "STXB3_HUMAN", "id": "O00186-1", "name": "Syntaxin-binding protein 3", "aln": "MAPPVAERGLKSVVWQKIKATVFDD----CKKEG----------EWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYK-NREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKIKAS--CSKSIRRCKEINISFIPHESQVYT-LDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKP----------------LDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP---IENDTYKYKTDG----KEKEA--ILEEEDDLWVRIRHRHIAVVLEEIPKLMKEIS-STKKATE--GKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK-FKLNIEKLCKTEQDLA-LGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIE-NESDMIRNWSYLG---------VPIVPQS---QQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDN--RLDSKEWPYCSQC---------------PAVWNGSGAVS-ARQKPR-ANYLE-DRKNGSK--LIVFVIGGITYSEVRCAYEVSQAHK-SCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61764-1", "uniprot_id": "STXB1_HUMAN", "id": "P61764-1", "name": "Syntaxin-binding protein 1", "aln": "MAP----IGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSR-AAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSP--HKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLD-AYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVKEV--LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTG--EKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKH-YQGTVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLG---------VPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61765-1", "uniprot_id": "STXB1_RAT", "id": "P61765-1", "name": "Syntaxin-binding protein 1", "aln": "MAP----IGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSR-AAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSP--HKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLD-AYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVKEV--LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTG--EKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKH-YQGTVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLG---------VPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08599-1", "uniprot_id": "STXB1_MOUSE", "id": "O08599-1", "name": "Syntaxin-binding protein 1", "aln": "MAP----IGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSR-AAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSP--HKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLD-AYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVKEV--LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTG--EKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKH-YQGTVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLG---------VPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07327-1", "uniprot_id": "ROP_DROME", "id": "Q07327-1", "name": "Protein ROP", "aln": "-------MALKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINK-KREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSC-AAGKIKTLKEINIAFLPYECQVFS-LDSPDTFQCLYSP--AFASIRSKHIERIAEQIATLCATLGEYPNVRYRSD-----------------WDRNIDLAASVQQKLD-AYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLP---IVNDVYRYTPG--PNQPDKEV--LLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSA--DKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKS-YQNYVDKLCRVEQDLA-MGTDAEGEKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSCLG---------INVIADSRKKQYSVP-RKERTTESTYQMSRWTPVIKDIMEDCIED--KLDLRHFPFLEGR---------------AQNTNYHAPTS-ARYGHWHKDKGQAQVKNVPR--LIVFIVGGVSMSEMRCAYEVTNAVR-NWEVLVGSSHILSPEIFLSDLGSLSKED---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64324-1", "uniprot_id": "STXB2_MOUSE", "id": "Q64324-1", "name": "Syntaxin-binding protein 2", "aln": "MAP----LGLKAVVGEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSR-LAKAVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCP--FRAGERGRQLDALAQQIATLCATLQEYPSIRYRKG-----------------PEDTAQLAHAVLAKLN-AFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLD---IEQDTYRYETTGLSESREKAV--LLDEDDDLWVELRHMHIADVSKKVTELLKTFCESKRLTT---DKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKH-FKGSVEKLCSVEQDLA-MGSDAEGEKIKDAMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSS-LIRNLEQLG---------GTVTNSAGSGTSSRLERRERM-EPTYQLSRWSPVIKDVMEDVVED--RLDRKLWPFVSDP---------------APVPSSQAAVS-ARFGHWHKNKAGVEARAGPR--LIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKTLDQKLEGVALP---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62753-1", "uniprot_id": "STXB2_RAT", "id": "Q62753-1", "name": "Syntaxin-binding protein 2", "aln": "MAP----LGLKAVVVEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSR-LAKVVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCP--FRAGERGRQLDVLAQQIATLCATLQEYPSIRYRKG-----------------PEDTAQLAHAVLAKLN-AFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLH---IEQDTYRYETTGLSESREKAV--LLDEDDDLWVELRHMHIADVSKKVTELLKTFCESKRLTT---DKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKH-FKGSVEKLCGVEQDLA-MGSDAEGEKIKDTMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSN-LIRNLEQLG---------GTVTNSAGSGTSSRLERRERM-EPTYQLSRWSPVIKDVMEDVVED--RLDRKLWPFVSDP---------------APVSSSQAAVSSARFGHWHKNKAGIEARAGPR--LIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLRTLDQKLEDIALP---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15833-1", "uniprot_id": "STXB2_HUMAN", "id": "Q15833-1", "name": "Syntaxin-binding protein 2", "aln": "MAP----SGLKAVVGEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSR-LAKVVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCP--FRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKG-----------------PEDTAQLAHAVLAKLN-AFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLD---IEQDTYRYETTGLSEAREKAV--LLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLTT---DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKH-FKGSVEKLCSVEQDLA-MGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSS-LIRNLEQLG---------GTVTNPGGSGTSSRLEPRERM-EPTYQLSRWTPVIKDVMEDAVED--RLDRNLWPFVSDP---------------APTASSQAAVS-ARFGHWHKNKAGIEARAGPR--LIVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIALP---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30619-1", "uniprot_id": "SEC1_YEAST", "id": "P30619-1", "name": "Protein transport protein SEC1", "aln": "-------MSDLIELQRNYLIGVLNQ----IETKN----------NLKFLIIDKTVETILSYLFLTPQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRP-PKYRRCHIRFLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNN--NCKALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIANAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVANVDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIAKNPLLVDRSNVKNTTDLLSVVAHLKDFDEERRRLILHKTLVDECLGENAERKLADISAIEQNLSGFGMDFSGEKIKHIIDDLLPALAMKEPTILDKLRYIIAYALFRGGIIELDFIKLLNFIGVTHEHENFQQYLKIFRNYDLIDFKLIKDKPKDKPFQKEWFHDTLVNDPNIYHTSRFVPAVGNILSKVIANPLLLSEQYFPYLKDKPIELLNEEEFQAGLANTSANSSSSLRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGISIPEIKAAYDQSNLKN--RDIFIGSDEILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPDFLLREMKPVAQPVSHVHLKSQDNSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRKSHHDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: *. .... : :.:::*. ::: : :.:* :: * . *: :.*:*:: *: .: : ** . *: .:: * .: :*. : . : :. . *.:.*: *.*.: *: .: : : :. .:.::*. * * :** . :* . :: : : :. :.:* *:* ** * :.:**::: ***:***: :* *:* . : . ::: * *: ::* ** . : :: : .. . * :: :: .: :: : * *.::*: : : .:. **:*: :* * .*:::*. : ::* * **:* : * : .* * :: :*: : . : : :: **: * : :::.. : : *. . :*: . . .* : .: :: :::**:: *::.**: :. ::::** .:*:* :*. : *.: ", "identical_positions": 83, "similar_positions": 199, "identity": "11.07%" }, { "cls_id": "homologset.agr.SGD:S000002572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Q3-1", "uniprot_id": "D4A0Q3_RAT", "id": "D4A0Q3-1", "name": "", "aln": "MRPLPVRMLLPRTPFARCRVTSLAGATRKGAERRTCAEAADGPMASSAGLALCAQTLVVRGGSRFLAFSTASSDDDCLFSYDCSTAEKKS---VQEDKGEDGQPADRGSDTILAST--FSKSGRYFALTDDSKR--LILFRTKP--WQCLSVR---TVVRRCTALTFTASEDRVLVADKSGDVYSFPVLDSGG---CGRLELGHLSMLLDVAVSPD---DQFVLTADRDEKIRVSWAAAPHSIEAFCLGHTEFVSRIFVVPSHPELLLSSSGDGTLRLWKYRSGCQLQCCDLASLQE-------------PGEHSVHKGLAASRIAFWGRESYVVLLCECVPVGFVFQLDASRQ---QLVFRQRLTFPHRVWDVVFEETRGLWVLQDCRDAPLALWRPMGSEWQAAP-DDAVSQRLCSHLRESWAMLEGS-AGADDGFRSLYKATFDNMTSYLKKKEERLKQQLKKK-RQRSPHPGSPEQTKKACPARAVSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP82-1", "uniprot_id": "WDR4_MOUSE", "id": "Q9EP82-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "aln": "-------------------------------------------MASSAGLALCAQTLVVRGGSRFLAFSTTGSDDDCVFTYDCSTAEKKA---TPEDKGEDGQPADTGSDSILAST--FSKSGRYFALTDDSKR--LILFRTKP--WQCLSVR---MVVRRCTALTFTASEDRVLVADKSGDVYSFSVLEPDG---CGRLELGHLSMLLDVAVSPD---DQFVLTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRILVVPSHPELLLSSSGDGTLRLWEYRSGRQLQCCDLAGLQE-------------PGEQPGHKGLAASRIAFWGQESYVVLLCECVPVVFVFQLDASRQ---QLVFRQRLTFPHRVWDVVFEEARGLWVLQDCRDAPLVLWRPVGGEWQAAP-DGAVSPRLCSHLRESWAMLEGS-VGTDDSFRSLYKATFDNMTSYLKKKEERLQQQLKKK-RQRSPFPGSPEQTKKACPGQSALSC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57081-1", "uniprot_id": "WDR4_HUMAN", "id": "P57081-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "aln": "-------------------------------------------MAGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKK----SQENKGED-APLDQGSGAILAST--FSKSGSYFALTDDSKR--LILFRTKP--WQCLSVR---TVARRCTALTFIASEEKVLVADKSGDVYSFSVLEPHG---CGRLELGHLSMLLDVAVSPD---DRFILTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRISVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQE-------------LVDPQAPQKFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQ---QLVYRQQLAFQHQVWDVAFEETQGLWVLQDCQEAPLVLYRPVGDQWQSVP-ESTVLKKVSGVLRGNWAMLEGS-AGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHAKKMRPGEATLSC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IGH4-1", "uniprot_id": "WDR4_DANRE", "id": "A4IGH4-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4", "aln": "----------------------------------------------MAVVCSKADWFVTSCSTTLVAVNLKQSREP--FVFDCSKAEKKPKEADVDNKSAGEGSEEKDSDSILAFA--ISASGKHVALTDDHKR--LVLFCTEPS-WKCISTR---WVVRRCTSLAFTQAEDELYVADKSGDVYSFSILEPHK---AGELKLGHLSMLLDVALSPD---DKYIITADRDEKIRVSFRRSPYNIQAFCLGHTEFVSSLLVPAGHPDWLLSGSGDGTVNVWHYETGRRLHSVDMRKFG--------------LDSENTEKRFAVSRIISSPDGQHVAVQCEGFPSVQLFTVDCGTEG--LLKPADTLTLPLSPWDVTFDSENQLWVLLESEDMKVLLYRHSEQHWRLCDSESPELKKVTNALQTQWHLFKGS-VGLESQFKHLYKVNFDNMASYLQKKQERLDLEHKKR--AAAANGSKPNKKSKTESGAVPQSTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W415-1", "uniprot_id": "WUHO_DROME", "id": "Q9W415-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho", "aln": "--------MCTTISFAEPEIVLGHGRRVLFVNPDDLQIFKEIELPPDLGLKGHTSQSQESCTAAAAASTATAASGQAPGGKEQQLANQPE---EGGTSASASGLGCATSTSVQNVA--YSPDGQLLAVTTSGKQKALLLYRSRPENARLLSAR---PLARASSALRFCSDSSSILVTDKTGDCYQYDCVEVEA---PPRLLLGHLSVVYDILWSED---QQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLT--EQHIASASGDKTLRVWNYIQGKELLQHEL---------------------PAPAVRLLVRQLEPEKVFQAAVLFYEHVDALGLYRLERSSDDTWSVTATQLVCAEAGSWSISNFTLTSDRIYITGAENERLSLRVYDIATGQPASSGVPEGWLKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNVSDYLERKKRRIEEQQQQK------------------CG-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03774-1", "uniprot_id": "TRM82_YEAST", "id": "Q03774-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82", "aln": "--------MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKWSDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIYSYIRNLRLTSDESRLIACADSDKS--LLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVS--SICCGKDYLLLSAGGDDKIFAWDWKTGKNLSTFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIIILEMSEKQKG--DLALKQIITFPYNVISLSAHN-DEFQVTLDNKES--------------SGVQKNFAKFIEYNLNENSFVVNNE---KSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSS---------------LRKHGEHYS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . ::: . : * .. .* : . * *::: . :. * . : .:: : . : ::** ** *. . . ***:*:: *: * .:.::*.***::*::: . :. : :** .*** : : *..** .: *.: * .* . : . :: ... : : :. . : : : .: : : . : * :. : .:. :. : :*:. . . ", "identical_positions": 35, "similar_positions": 97, "identity": "7.09%" }, { "cls_id": "homologset.agr.SGD:S000002573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54921-1", "uniprot_id": "EXOC2_RAT", "id": "O54921-1", "name": "Exocyst complex component 2", "aln": "--------------------------MSRSRQPPLVTGISPNEGIPWTKVTIRGENLG--TGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVD---EMNYYDMRTDRNKGIPPLSLRPANPLGIEIE-KCKLPQKN-----------LEVLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGNPGPHSPMLDLDNDARPS---------VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYG-----GWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIV---DNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKT--QEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQ-CVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASGADKKLLEELLNKFKSSMHLQLTCFQAASPTVMKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4H1-1", "uniprot_id": "EXOC2_MOUSE", "id": "Q9D4H1-1", "name": "Exocyst complex component 2", "aln": "--------------------------MSRSRQPPLVTGISPNEGIPWTKVTIRGENLG--TGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVD---EMNYYDMRTDRNKGIPPLSLRPANPLGIEIE-KCKLPQKN-----------LEVLFHGMSADFTSENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGHPGPHSPMLDLDNDVRPS---------VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYG-----GWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVV---DNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKT--QEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQ-CVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASGADKKSLEELLNKFKSSMHLQLTCFQAASPAVMKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KP1-1", "uniprot_id": "EXOC2_HUMAN", "id": "Q96KP1-1", "name": "Exocyst complex component 2", "aln": "--------------------------MSRSRQPPLVTGISPNEGIPWTKVTIRGENLG--TGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVD---EMNYYDMRTDRNKGIPPLSLRPANPLGIEIE-KSKFSQKD-----------LEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPS---------VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYG-----GWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIV---DNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKT--QEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQ-CVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQQ9-1", "uniprot_id": "EXOC2_DROME", "id": "Q9VQQ9-1", "name": "Exocyst complex component 2", "aln": "-----------------------------MAPQPVVTGLSPKEGPPGTRVIIRGEFLG--TRVQDLIGLKICGSDCLLSAEWKSPNKIIARTGPAKG-KGDIIVTTLSGGVGTSTVQFRAYH-ETIGPLKESAVWIE---ESPSQNFAWGR-RTLAQSGLTQEDPLGLSIEGNEQKIPED-----------LRDLFPEACGDLSQEHFSPAWFLLENHLATSFEDLKAGLSYLKRKVESQKEGQLSFLKSNAGSVIDQLDTLMNIRDKLQEDVKLHGN-ETLNILETSIENSISESQKIFTDVLVRKEKADSTR-SVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTEIPIFRKVLEEVDHRILSIRKQLHEKVVKMPQSVEQQKKLIKALISLELQ--------------------QSGTPIGDKLRNIDPAWDAIEARAKYLEWT---------FRQTFDQHTSKDSGAQEKAKNRDSS--QAPNRVNFCEELCDIAASQLPDLWRLGQLYFTGELRGPHDPKPG-------------DFKRMVLNAIEKFCVYLRLAILIATDQRALRQSSGLAWPIGSASATHQFLPWIPQCLRFTRIAYATLISLDLPSEALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELGVEEYPGATLLPAALETLLIETLDEVQSVCMQRETREGNLLEPQSDGQREVTQRLQEFLSAFSAVIEELAFHSHDEETPTHNVSQLLGFPNAQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPTLAIETARYTVNQLFTNLLEEYVEHKGDPLVGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLVGVYSEIYSISPALLRPILESIVQTISEELARLMS-CVQRFSFTGAIQAHVDIRLLRDSLEGYVNETAKNYFMEALEAINPPLSGEQKRKADEILERVKRNMRLQLLCFSVKDP-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P89102-1", "uniprot_id": "SEC5_YEAST", "id": "P89102-1", "name": "Exocyst complex component SEC5", "aln": "MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELGVETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRLNYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVKIKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQKILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSG--HMISKIIHSQRLILQNNTNQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQPSSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKENILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLKDSTGDITRSNKDSGSPLDYG---FIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNGITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVY--ETVTFSSKSQDSSKNLTFEYGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIISMEAVLEA---------ILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKNLELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFR-VGDYIIEALMILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFFQKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : * : ::. * . : . . : . .:: . . . : . * ...:. : :.:. *.:* :: : .: : :. . : * . : :: :. * : *. : : : .:: * : * : .. . . :.. . .: . :: ::: . . . : . : :: .:: : : *..: . * :.: * : . .*. : *: : . .. ... : . :: *:: *:. : : : .: : .. .::* . . : . : : . :.: . . :. : :. : *: . .:: . . . : .* . : . : . . . * ::.: :. * *::..: : :. : : *. . ..: . * * : : : . . : : . : .: . :... ::* . : : . . . :.: : *:* * .. * .: : * :.:: :: :*:. : .::* :: : : * *. :: *::* : *. *: :* ::. * . :. * :* *::* ::: ::. : : :. : .*: :. :: :*: .. .:: * . . ", "identical_positions": 50, "similar_positions": 278, "identity": "5.03%" }, { "cls_id": "homologset.agr.SGD:S000002574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0H5-1", "uniprot_id": "TAF10_MOUSE", "id": "Q8K0H5-1", "name": "Transcription initiation factor TFIID subunit 10", "aln": "MSCSGSGADPEAATACAASVAGPAPLVSAPAALPTSTAAESKASPAGTAGGPVAGVATAGTGPVAARAGEPAERRGPASVAAGGAAPPEGAMSNGVYALPSAANGEVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGT----ASGSSRSKSK--------------------------DRKYTLTMEDLTPALSEYGINVKKPHYFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12962-1", "uniprot_id": "TAF10_HUMAN", "id": "Q12962-1", "name": "Transcription initiation factor TFIID subunit 10", "aln": "MSCSGSGADPEAAPASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGGTGPLAARAGEPAERRGAAPVSAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGT----ASGSSRSKSK--------------------------DRKYTLTMEDLTPALSEYGINVKKPHYFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9U5W9-1", "uniprot_id": "TAF10_DROME", "id": "Q9U5W9-1", "name": "Transcription initiation factor TFIID subunit 10", "aln": "MASDGE----------DISVT-PAESVTS----ATDTEEEDIDSPLMQS-------------ELHSDEEQPD-------------------------------VEEVPLTTEESEMDELIKQLEDYSPTIPDALTMHILKTAGFCTVDPKIVRLVSVSAQKFISDIANDALQHCKTRTTNIQHSSGHSSSKDKKNPK----------------------DRKYTLAMEDLVPALADHGITMRKPQYFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9XZT7-1", "uniprot_id": "TAFAB_DROME", "id": "Q9XZT7-1", "name": "Transcription initiation factor TFIID subunit 10b", "aln": "MVGSNFG----------IIYHNSAGGASS----------HGQSSGGGGG-------------------------------------------------------GDRDRTTPSSHLSDFMSQLEDYTPLIPDAVTSHYLNMGGFQSDDKRIVRLISLAAQKYMSDIIDDALQHSKARTH-MQTTNTPGGSKAK--------------------------DRKFTLTMEDLQPALADYGINVRKVDYSQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12030-1", "uniprot_id": "TAF10_YEAST", "id": "Q12030-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF10", "aln": "-MDFEEDYDAEFDDNQEGQLETPFPSVAG----ADDGDNDNDDSVAENMK-------KKQKREAVVDDGSEN------------------------------AFGIPEFTRKDKTLEEILEMMDSTPPIIPDAVIDYYLTKNGFNVADVRVKRLLALATQKFVSDIAKDAYEYSRIRSSVAVSNANNSQARARQLLQGQQQPGVQQISQQQHQQNEKTTASKVVLTVNDLSSAVAEYGLNIGRPDFYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:. .. * . .. : ::: ::. .* ****: : *. ** * :: **:::::**::*** .** ::.: : . :: : * .*:::** .*::::*:.: : .: ", "identical_positions": 25, "similar_positions": 54, "identity": "10.08%" }, { "cls_id": "homologset.agr.SGD:S000002575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63692-1", "uniprot_id": "CDC37_RAT", "id": "Q63692-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AEGGGQVELERLRAEAQQLRK----------------EERSWEQKLEDMRKKEKNMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKAEED--SEEAREQKHKTFVEKYE------KQIKHFG--MLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------QQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSGEAK----EGEEAGPGDPLLEAVPKAGNEKDISA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61081-1", "uniprot_id": "CDC37_MOUSE", "id": "Q61081-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AESDGQVELERLRAEAQQLRK----------------EERSWEQKLEDMRKKEKNMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKAEED--SEEAREQKHKTFVEKYE------KQIKHFG--MLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------HQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSGEAK----EGEEAGPGDPLLEAVPKAGNEKDVSA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16543-1", "uniprot_id": "CDC37_HUMAN", "id": "Q16543-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AEG-GKAELERLQAEAQQLRK----------------EERSWEQKLEEMRKKEKSMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKTEED--SEEVREQKHKTFVEKYE------KQIKHFG--MLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------RQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAK----EGEEAGPGDPLLEAVPKTGDEKDVSV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24276-1", "uniprot_id": "CDC37_DROME", "id": "Q24276-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSKWKNIEISDD-EDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARLMDVKERISKKDG-DEEALKKELEKIEAEGKELDR----------------IES-------EMIKKEKKTPW------------------------NVDTISKP------------GFEKTVINKK---------------AGRKPDENLSEEEREQRMKQFVKENE------KLCQQYG--MLRKYDDSKRFLQEHLHLVGEETANYLVIWSINLEMEEKHELMAHVAHQCICMQYILELAKQLDV------DPRACVSSFFSKIQHCH------PEYRAQFDSEIEGFKGRIQKRAQEKIQEAIAQAEEEERKERLGPG----------------GLDPADVFES-LPDELKACFESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGD----KKEEDDSDD-VAGGEEKTDDAKSESAAKEEPIYTGVSTEDVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9CZP7-1", "uniprot_id": "CD37L_MOUSE", "id": "Q9CZP7-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQRERMCLW------------------------NMDAISKD------------VFNKSFINQ-----------------DKRK------TEEEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPHLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYAQS---QSLQPVTVQN---HVPHS----------------GVGCIGSLES-LPQNPD-------------------------SLQCCTPAPLCSVDSVVHK--------EDDD-RMMDTV-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIC3-1", "uniprot_id": "CD37L_RAT", "id": "Q5XIC3-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQRQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQRERTCLW------------------------NVDAISKD------------VFNKSFINQ-----------------DKRK------TEDEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKARVRLYAQS---QSFAPVTVEN---HAPHS----------------GVGCIGSAEP-LPQNPD-------------------------SLQCCPPAPLCSVDSVVHK--------EDDD-RMMDTV-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L3B6-1", "uniprot_id": "CD37L_HUMAN", "id": "Q7L3B6-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSLPRAEGEAEEESD-FDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQREKMCLW------------------------STDAISKD------------VFNKSFINQ-----------------DKRKD-----TEDEDKSESFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYSQS---QSFQPMTVQN---HVPHS----------------GVGSIGLLES-LPQNPD-------------------------YLQYSISTALCSLNSVVHK--------EDDEPKMMDTV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7YY97-1", "uniprot_id": "CD37L_DANRE", "id": "A7YY97-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "--------------------------------------------------MASLCQRQQHCVKASIASEWQLAEAQDQLCGLELHSSESVEQERARALASSTELSH----------------TEHQWRLKERMLG---TLCP----------------------------EANRD------------VFDKSIINI-----------------TQSWPN----ESDPDKSLNFVQRNE------ELLKHFG--MLGRWDDSQRFLAEYHHLICEETANYLILWCFRLQAEKKEALMEQVAHQAVVMQFILEMARNTQQ------DPRGCFRHFFQKAKAGQ------EGYLDVFHTELQAFKDRVKEYTMKSTGETPKDTVHQN---TPPAC----------------CLDPKEVFES-LPQELKTCIQMQDMQILQNVLSSMNPQVAEYHVKRCLEAGLWTNIPRTSKDE----SSEVDEWKMMET------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06101-1", "uniprot_id": "CDC37_YEAST", "id": "P06101-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "---------MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . : : :: : * : : *..:.:* . *:. : : ..:* : .:..*:::* : :: *: . *:: .: : . . : :: ** * :* *: . : . ** * . : .. :: :: * : :: : :. :*:: . :: : . : : ", "identical_positions": 19, "similar_positions": 77, "identity": "3.68%" }, { "cls_id": "homologset.agr.SGD:S000002577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3X9K3-1", "uniprot_id": "BIG1_MOUSE", "id": "G3X9K3-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "--------------------------MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKVETEKQSPPHGEAKAGSGTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGRAPDSTTPGKKLIDRIIETICGCFQGPQTDEG---VQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR--MENQAL------------------QEAKQMERERHRQQQHLLQSPVSHHEPESPHLRYLPPQTVDHINQEHEGDLEPQTHDVDKS--LQDDTEPENGSDISSAENEQTEADQATAAETLSKN---DILYDG---DYEEKPLDIVQSIVEEMVNIIVGDMGEGMAISASTEGNTGTVED------------------------------------------GSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGP-SPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPVFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEK-PSEQEISEVKHPETINRYGSLNSLESTSSSGIGSYSTQMSGT----DNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMKETKELTIPTKST---------KQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREG------SLTGTKDQAPDEFVGLGL---VGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMSVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPTSGEAEPPSPSAVSEKPLDAISQKSVDIHDSIQPRSSDNRQQAPLVSVSTVSEEVSKVKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCREALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDSRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGIVFQISQPPEQELGINRQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A631-1", "uniprot_id": "BIG1_RAT", "id": "D4A631-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "--------------------------MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKVETEKQSPPHGEAKAGSGTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGSAPDSTTPGKKLIDRIIETICGCFQGPQTDEG---VQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR--MENQAL------------------QEAKQMERERHRQQHHLLQSPVSHHEPESPHLRYLPPQTVDHIAQEQEGDLDPQTHDVDKS--LQDDIEPENGSDISSAENEQTEADQATAAETLSKD---DVLCDG---ECEEKPQDIVQSIVEEMVDIIVGDMGEGTAVSASADGNAGAVED------------------------------------------GSDSENVQANGIPGTPISAAYTPSLPDDRLSVSSNDTQESGNSSGP-SPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPVFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEK-PSEQEISEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGT----DNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQAGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMKETKELTIPTKST---------KQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTDVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREG------SLTGTKDQAPDEFVGLGL---VGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTSGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMNVAPEDRVWVRGWFPILFELS-CVINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPTSGEAAPPSPSAMSEKQLDAISQKSVDIHDSAQPRSSDNRQQAPLVSVSPASEEVSKGRPTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYTDESRVSAWEEVQQRLLNVCSEALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGIVFQISQPPEQELGINKQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6D6-1", "uniprot_id": "BIG1_HUMAN", "id": "Q9Y6D6-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "--------------------------MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQTDEG---VQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR--MENQAL------------------QEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTNDVDKS--LQDDTEPENGSDISSAENEQTEADQATAAETLSKN---EVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGTIED------------------------------------------GSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGP-SPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPIFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEK-PSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGT----DNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMKETKELTIPTKSS---------KQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREG------SLTGTKDQAPDEFVGLGL---VGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMNVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPNSGETAPPPPSPVSEKPLDTISQKSVDIHDSIQPRSVDNRPQAPLVSASAVNEEVSKIKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCSEALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGVVFQISQPPEQELGINKQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q904-1", "uniprot_id": "A0A2R8Q904_DANRE", "id": "A0A2R8Q904-1", "name": "", "aln": "--------------------------MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKQESEKLSSPVGDNKSSSSTLPPIKS-KSSFIEADKYFLPFELACQSKCPRIVITSLDCLQKLIAYGHLTGSAPDNTTPGKKLIDRIIETICGCFQGPQTDEG---VQLQIIKALLTAVTSQQIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR--MENQALTNHKISWSLASRKRDRQLQEAKQMERERHRQH-----SPVSQQEPESPGQRHT-ETPGKTLPAEGNGGPGHQGGKVEQGSPPYESPEPENGSDFCPAENEQTEADQATAAAQSAAEHATEASEEDERQNYEEKAQEIVESVLLEVVNTVATGNMYVTEMKASHEGEAESAEVSPNSLEEEGGL-------------------------------GSDNENVHANGIPGTPISASFTPSLPDDRLSVSSNDTQESVATSGQ-APGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKVLSLQLLLSILQNAGPIFKTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSYDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGGH---------------------------------------ELGTTPLQELTLRKKGLECLVSILKCMVEWSKDQYVNPNSQTSLGQEK-PSEQESNESKHPETINRYGSINSLDSTASSGIGSYSTQMSGT----DNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSIQVGEFLGDNDRINKEVMYAYVDQMDFQGKDFVPALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYDEIAGKKISMKETKELTL--KSN---------KQSVASEKQRRLLYNVEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTASSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEIMKCISQLELAQLIGTGVKARYISGTVRGKEG------FITSTKEQTSDEYLGL------GGNVDRKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVVRCIAQMVNSQAGNIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTNVFEKHFPATIDSFQDAVKCLSEFACNASFPDTSMEAIRLIRHCAKYVSDRPQAFKDYT----SDDMNVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEVMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYFESLSDVLLDDILSQLYWCVQQDNEQLARSGTNCLENVVILNGEKFNPETWDKTCNCMLDIFKTTIPHMLLTWRP-AGAEGDHMTQLESDKQLDSISQKSVDIQT----RSDDQQSVNSMEKALADNRRYSQFSVASEAQEQRLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENFAAAQRDALDAD---------------IHVDTQDQGMYRYLTSEQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYTDPSRRDAWEEVQRRLLNVCSDAVAYFLTLTS---ESHREAWTNLLLLFLTKVLKISDDRFKAHASRYYPLLCEIMQFDLIPELRAVLRKFFLRIGLVFQITNSLETNQTVSNA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2A5R2-1", "uniprot_id": "BIG2_MOUSE", "id": "A2A5R2-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "--------------------------MQESQ-TKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQ-------RLGAAAPP-----KANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEG---VQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTR--MENQVL------------------QEARELEKPMQSKP----QSPVIQATAGSPKFSRLKQSQAQSKPTTPEKAELPNGDHAQSG---LGKVSLENG------EAPRERGSPVSGRAEPSRG-------------TDSGAQEVVKDILEDVVTSAVKEAAEKHGLPEPDR--------------------------------------------------ALGALECQECAVPPGVDENSQTNGIADDRQSLSSADNLEP-DVQGH-QVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSH---------EMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQER-LPDQEMGDGKGLDMARRC-SVTSVESTVSSG-----TQTAIQ----DDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-AAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYDEIEGKKIAMKETKEHTIATKST---------KQSVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG------SLKG-HSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFR-IVFRIFDNMKLPEQQ------SEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHVLLTWRPAGMEEE--VSDRHLDVDLDRQSLSSIDRNA-------SERGQSQLSNPTDDSWKG------APYAHQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAE---------------IHIETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWDEIQQRLLRVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKISDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGLVYKIWIPEEPSQVPAALSSTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSU1-1", "uniprot_id": "BIG2_RAT", "id": "Q7TSU1-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "--------------------------MQESQ-TKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQ-------RLGAAAPP-----KANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETVCNCFQGPQTDEG---VQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTR--MENQVL------------------QEARELEKPIQSKP----QSPVIQATAGSPKFSRLKQSQAQSKPTTPEKTELPNGDHARSS---LGKVNSENG------EAHRERGSSISGRAEPSGG-------------SDNGAQEVVKDILEDVVTSAVKEAAEKQGLPEPDQ--------------------------------------------------APGVPECQECTVPPAVDENSQTNGIADDRQSLSSADNLEP-DAQGH-PVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSH---------EMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQER-LPDQEMGDGKGLDMARRC-SVTSVESTVSSG-----TQTAIP----DDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-AAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYEEIEGKKIAMKETKEHTMATKST---------KQNVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG------SLKG-HSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFR-IVFRIFDNMKLPEQQ------SEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFRTTIPHVLLTWRPAGMEEE--VSDRHLDVDLDRQSLSSIDRNA-------SERGQSQLSNPTDDSWKG------APYANQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAD---------------IHIETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWGEIQQRLLTVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKINDEKFKAHASVYYPYLCEMMQFDLIPELRAVLRKFFLRIGLVYKIWVPEEPSQVPAAS-TAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6D5-1", "uniprot_id": "BIG2_HUMAN", "id": "Q9Y6D5-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "aln": "--------------------------MQESQ-TKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAEIEKQ-------RLGTAAPP-----KANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICSCFQGPQTDEG---VQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTR--MENQVL------------------QEARELEKPIQSKP----QSPVIQAAAVSPKFVRLKHSQAQSKPTTPEKTDLTNGEHARSD---SGKVSTENG------DAPRERGSSLSG--------------------TDDGAQEVVKDILEDVVTSAIKEAAEKHGLTEPER--------------------------------------------------VLGELECQECAIPPGVDENSQTNGIADDRQSLSSADNLES-DAQGH-QVAARFSHVLQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTH---------EMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGH---------------------------------------ELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQER-LTDQEIGDGKGLDMARRC-SVTSMESTVSSG-----TQTTVQ----DDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLG-TSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSSIYEEIEGKKIAMKETKELTIATKST---------KQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAP---FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREG------SLKG-HTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMAIRCIAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTCHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYT----SDDMNVAPGDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFR-IVFRIFDNMKLPEQL------SEKSEWMTTTCNHALYAICDVFTQFYEALNEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPEVWDETCNCMLDIFKTTIPHVLLTWRPVGMEED--SSEKHLDVDLDRQSLSSIDKNP-------SERGQSQLSNPTDDSWKG------RPYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAD---------------IHIETEDQGMYKYMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNS---ESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPAALSPVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJW1-1", "uniprot_id": "Q9VJW1_DROME", "id": "Q9VJW1-1", "name": "", "aln": "-------------------------MHNNSTKTKEMFIVRALEKILADKDIRRSHHSQLKKSCDSALEQIKAELISAGQIAEGNELPCAALPLPKNDAASIINAETYFLPFELACKSRSPRIVVTALDCLQKLIAYGHLTGSIQDSANPGHLLIDRIVVTIYGCFSGPQTDEA---VQLQIIKALLTVVTSQHVEIHEFTLLQAVRTCYDIYLSSKNLVNQTTARATLTQMLNVIFAR--MENQVY----------------------ELPPP---------------------------------------------------------NSNPTNG-------SIHSEDCNGSGEESLRDS-----------------DEVIASELLAEIISAAYNEAMKDQ----------------------------------------------------------------ESVGEPEPTLNG-------NDYSSHSDHDSVELHSENDA-VVTAKFTHILQKDAFLVFRALCKLSMKPLPDGHPDPKSHELRSKVLSLHLLLLILQNAGPVFRSN---------EMFIMAIKQYLCVALSNNGVSLVPEVFELSLSIFVALLSNFKVHLKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICADAQSVVDIYVNYDCDFSAANLFERLVNDLSKIAQGRQAL---------------------------------------ELGANPMQEKSMRIRGLECLVSILKCMVEWSKDLYVNPNMPVPPMQVQSPTSTEQDQADTTIQTMHSGSSHSLNSN----------QEQLQ----DLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLG-ATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTG--------KQAFITEKRRKLLWNMEMEVISLTATNLMQSVSHVKSP---FTSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLERDAYVQALARFTLLNANSPINEMKAKNIDTIKTLIMVAHTDGNYLGSSWLDIVKCISQLELAQLIGTGVRPQFLSGAQTTLKD------SLNP----------------------------SVKEHIGETSSQSVVVAVDRIFTGSMRLDGDAIVDFVKALCQVSVDELQ----QQQPRMFSLQKIVEISYYNMERIRLQWSRIWQVLGEHFNAVGCNSNEEISFFALDSLRQLSMKFMEKGEFSNFRFQKDFLRPFEHIMKKNASPAIRDMVVRCIAQMVNSQAHNIRSGWKNIFSIFHLAAGDNEEPIVELAFQTTGKIIGDLYKRQFAIMVDSFQDAVKCLSEFAT-ARFPDTSMEAIRLVRTCAQCVHEAPQLFAEHAGM--ENDASVAEEDRVWVRGWFPMLFSLS-CVVNRCKLDVRTRALTVLFEIVKTYGESFKPHWWKDLFN-VIFRIFDNMKLPEHV------TEKSEWMTTTCNHALYAIIDVFTQYFDVLGHLLLEELFAQLHWCVQQSNEQLARSGTNCLENLVISNGFKFNESTWDKTCQCILDIFNATLPQDLLSWRPKAHSSN-------------------------------------------------------NIPQEHNHFEALHIRCVVQLELIQTMDNIVFFPATSRKEDAETLAQAAADLTGGRSGSQ--------SQLLECQREEQGMYGYLRTRQLLTLADCLMQSHRFAKRFNADHDQRSLLWRAGFKGSVKPNLLKQETSSLACVLRIFFKMYGDENRRSDWPGIEQELVQVCKEALGYYLSLQS---EAHRDAWTSLLLLILTRLLKMSDARFATHVSNYYSLLCEMMCFDLKPELRSVLRRVFMRIGPVFNIMSVK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11075-1", "uniprot_id": "SEC7_YEAST", "id": "P11075-1", "name": "ADP-ribosylation factor guanine nucleotide-exchange factor SEC7", "aln": "MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKETNGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDEDEDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNSSSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGSNTNSTIILVKTTLETILNDKDIKKNS--------------------NAQKAIERTLQKFKEFDPQTTNNPHYVDSILVFEALRASCRTKSSKVQSLALDCLSKLFSFR-SLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPLET-ELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCIVSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPG--VFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGR-DLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNLQN---LEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLN-RMLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRR----ENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDK-IPNLLKQETSAAAVLLDIMFQLYLNDDEKK--ADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:. : .* *. *:. : ..:: . : :: . . . : : * . .. :: * :. . *. * .. .. .. : . .*.: :* : : :* ..:: . : : :* *:*:. .::* . * : .:: : :*. : . * : : .:: : . . : . . * . . .: ******** :.*:. *** * :** :***::**::: :::: :* :: *: :*:*** :.**.*..* :. ***::* *: *::*:: .: :* **:.**:: * * .:*: ::: .:..: *** *.: :*::*:****: . .*::* *: *:::* * ::. : ::: .*:*:**:*:.: .*::. . . . .. . . . : * :. . * * :* * :* :. * :**.**::.: * :: :* : .**::* : * ** *:::*:. . :* *::* ** ..* *** :*:.******.*****:* *** *: : * :* .***.***::*:***.*****.*:*:**: ::::: *.**.:.: ***.::*..:::** ::* : . . . : . :.. : :* : :: .: ::: :.: :. : :*.*::**:.:*: * .:*** : ::: ** : :. **:*:: :::**. * :. * ::* **.:* * : *:* **:::: *: ** ::**** .** :*: :**:* ***..*: :.. . * **..:** :*.*** * .*.*:*****:: * **::*: ********:*::.**** **:*:*: :* *:*. ** :. *.* : :**:********:*:: *::.*.**:***:***: ::.. .. :::* :.*: ::: ::: .*:**** *: :: :* . ** : : : . .:. *:*.: * : *:: * . *:.*:. :* : * : : : ..: : . :: ***:** :. ::. .*:**:*.*. :*: : :** .: .:*:.: . ::* **. :. . : : *::** :** : :**:: : * :*. .:. * *: *.*: :** * .**::::: * **. *:: : .:* * .: *: : * : : .*: ** . .: : *.: : * :. :::.: : .. : : * :*: *:: ** : *: * .* . .. *********: * * *:*::* : .. . : .*: :* :.: :::: . * :** .::: :* ::.* * : . *. : ::: .: .*** .:::.: *:* :: ", "identical_positions": 378, "similar_positions": 566, "identity": "18.35%" }, { "cls_id": "homologset.agr.SGD:S000002579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYD5-1", "uniprot_id": "Q6AYD5_RAT", "id": "Q6AYD5-1", "name": "", "aln": "-----MDPSSGGGGGGGGGGGGSSSSSSDSAPDCWDQTDMEAPGPGPCGGG--------SMAAVAEA------------QRENLSAAFSRQLN-----VNAKPFVPNVHAAEFVPSFLRGPA----------QPPLSPAGAAGGDHGAGSSAGGP-------SEPVESSQEQSL--CEGSNSTVSMELSEPVVENGETEMSPEESWEHKEEISEAEPAGGGSSGDGRPPEESTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLIPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDSVAPGENLKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R050-1", "uniprot_id": "ERF3A_MOUSE", "id": "Q8R050-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "aln": "-----MDPSSGGGGGGGGGG---SSSSSDSAPDCWDQTDMEAPGPGPCGGGGSGSG---SMAAVAEA------------QRENLSAAFSRQLN-----VNAKPFVPNVHAAEFVPSFLRGPA----------QPPLSPAGAAGGDHGAGSGAGGP-------SEPVESSQDQS---CEGSNSTVSMELSEPVVENGETEMSPEESWEHKEEISEAEP-GGGSSGDGRPPEESTQEMMEEEEEIPKPKSAVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDSVAPGENLKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15170-1", "uniprot_id": "ERF3A_HUMAN", "id": "P15170-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSEPIVENGETEMSPEESWEHKEEISEAEP-GGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q149F3-1", "uniprot_id": "ERF3B_MOUSE", "id": "Q149F3-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "aln": "-----MDLG---------------SSS-DSAPDCWDQVDMEAPGSAPSGDGIAPAAMAAAEAAEAEA------------QRKHLSLAFSSQLN-----IHAKPFVPSVSAAEFVPSFLPGSA----------QPPAPTASS--CDETCIGGAGEPEGKRMEWGAPVEPSKDGPLVSWEGSSSVVTMELSEPVVENGEVEMALEESWEL-KEVSEAKP-EA-SLGDAGPPEESVKEVMEEKEEVRKSKSVSIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSD-DAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJE3-1", "uniprot_id": "A0A096MJE3_RAT", "id": "A0A096MJE3-1", "name": "", "aln": "-----MDLG---------------SSS-DSAPDCWDQVDMEAPGSAPSGDEIAPAATAAAEAAEAEA------------QRRHLSLAFSSQLN-----INAKPFVPSVSAAEFVPSFLPGSA----------QLPAPTASS--CDETCIGGAAEPQGKRMEWGAPVEPSKDGPLVSWEGSNSAVTMELSEPVVENGEVEMALEESWEL-KEVSEAAP-EG-SLGDVGPPEESGKEVMEEKEEIRKSKSVVRPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSD-DAETDFVAPGENLKIRLKGIEEEEILPGFILCEPNNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYD1-1", "uniprot_id": "ERF3B_HUMAN", "id": "Q8IYD1-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "aln": "-----MDSG---------------SSSSDSAPDCWDQVDMESPGSAPSGDGVS--------SAVAEA------------QREPLSSAFSRKLN-----VNAKPFVPNVHAAEFVPSFLRGPT----------QPPTLPAGSGSNDETCTG-AGYPQGKRMGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEP-GGGSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGILSD-DTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK85-1", "uniprot_id": "Q9VK85_DROME", "id": "Q9VK85-1", "name": "", "aln": "----------------------MAAQENTEISTKFSTLNVNAVEFVPSFSYNS-------VVNVAEE------------AAAVVVAAAAAEET-----ADPGPASGSATPATTPDSVGSGGS----------TAGAAPPPPTAQGAGAAAPSAQPPTSSSNSASPAPGSPATTPSAGAAAADPTPIDGLNPSDKIANNETDPADSWDVDDAVITPED---------EEVEDAEFTEGEATPKVSKKKVVKVEENRSKREHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGKTVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYGLKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVESGTARKGQNLLVMPNRTQVAVDQLFSD-DFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05453-1", "uniprot_id": "ERF3_YEAST", "id": "P05453-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit", "aln": "MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGGYYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKKVGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDLKISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVKIAE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. : . : : : : . ::**.::*:*********:**::: *** **:**:*******:: .*: *****.:***:***:.***:***:*:***:::::********* :*.:*****:***:.**********:****::********:**** **: ::*::********:*. **::* .:: :*: :*:. .*: *** ** :* .:*:: **** * .:: ::* : .:* :.*: :**. * **:**:* **:*** ***. ::***: * : : .: : *. . **::*:::**:***:: ***:* . * :: * .*:.*:* ****..*:..*:*:* . *** : *: ::* :. ***. * *.*:. * :. . :*:* :: :**:*******:..******::*:. ", "identical_positions": 203, "similar_positions": 152, "identity": "29.51%" }, { "cls_id": "homologset.agr.SGD:S000002580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1RE97-1", "uniprot_id": "F1RE97_DANRE", "id": "F1RE97-1", "name": "Kinase", "aln": "MCVPHTMEAGKHSASQGQGSCGGVPLEPFIHQVGGHTSMMRYDDHTVCKPLITREQRFYESLPPEMKEFTPEYKGVVLVCFEGDSDGYIN----------------------------LVAYPYEESEGLDHEELSERDQPRRKHSRRSLHRSSSEHKEDRHAHDSDGN--------DNLQELKSPLLDLQLHSDVPFQMLDSNSGLS------------------------------------------------------------SEKISHNPWSLRCHK----QQLSRMRSESKDRKLYKFLLLENVVHHFKYPCILDLKMGTRQHGDDASEEKAARQMKKCEQSTSATLGVRVCGMQVY---------------QMDTGHYLCRNKYYGRSLSIDGFRQALFQFMHNGTL--LRKDLFEPVLSKLCSLKAVLERQASYRFYSSSLLIIYEGKD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PESADSWQ---------------------------------------------------------------------------------------------------------------------------KPSELPSAKENQATSSENPAAS----------------------------------------------ELHTPPQVLN---VDVRMIDFAHSTFKG-------FRDDQTVHDGPDRGYVFGLESLINILQEIREENQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2E9-1", "uniprot_id": "Q9W2E9_DROME", "id": "Q9W2E9-1", "name": "Kinase", "aln": "--MVYFLGDWGMGDSDLSSYQQHVPNIQQPRRIHGHDLLLQQQQQQLPQQQQQQQQQQQQQQQEFVAQISSSLSQVQAQLQFASGSSFLQQGSSPSPSQQQHGPVSSSSLVTANLQQLSVSSSNASSSSSNNNSASGCNTPTKPQKQKPLLLPEAAASTATAVGKSSKNPQLSKDLLDNEDEVALHPLSNQVGGHTRLLLLNQSTVIKPLNLRELDFYQNIPQDILKFVPKYKGVMQATTMGGAKLDKRYSPSFRDDAAAVPVRKMSASKRKRDEVLRMKVHKNGQAAEVIKSISQLDNTNKQYFLMLENITSQFRNPCILDLKMGTRQHGDDASAEKRSKQMAKCAASTSGSLGVRLCGMQTY---------------LADLEQYAKRDKYWGRELNEGGFKTALHDFFHNGYR--LRIRVIRKILQRLLQLRRVIEKQSSYRFYSCSLLIVYEGFEENPMAPPPSMSQDEWPEAPRSATVPGTVFDYHPENSIDEDDLEDDDEAGNEAGDELEAHDTDDDLHLVAADSGNASATNSSTGGDACNYDADASNDSNSLLNLATRRHLHKRGFAEAAARGVKQTASHNTTTDEEEEDEHPAMPPPRTCGVMAAKAAAAAAGLAGKGQGAFIPISEETVFLDPEPALPSVTTSSPHSGDSWMNYSSNSSDDFSGLSEQIKAVASGRQTCNNSSDDASSDYESSIIGPTEAMFKRYKSQQSFDAATAADSASSPPLTAGNSSVSNGGTTVRSLVSPASSSASSLKSVKGAVKRLRCNDDDQQSASLGESDLREAKKSTITSTPVSAVSSPAKAAPQLRSCESISNQQSLLSGLLLDNNNEQRRNALLQQSSKSLDMSAPPTDDNQCFVDVRLIDFAHTAFVPRNGTMLPTPAAAPVHHGPDGGFLTGLDSLNRLLNEIVAEERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8NFU5-1", "uniprot_id": "IPMK_HUMAN", "id": "Q8NFU5-1", "name": "Inositol polyphosphate multikinase", "aln": "-----------MATEPPSPLRVEAPGPPEMR----TSPAIESTPEGTPQPAGGRLR--------FLNGCVPLSHQVAGHMYGKDKVGILQ--------------------------------------HPDGTVLKQLQPP--PRGPRELEFYNMVYAADCFDG---------------------VLLELRKYLPKYYGIWSPPTAPN----------------------------------------------------------------------------------------------DLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYP--LMEEIGFLVLGMRVY---------------HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYC--LRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSSQP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSSTAN-----------------------------------------------------------------------------------------GKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMS---------------QEHLNGNVLSQLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSN----------------TIDEGYVYGLKHLISVLRSILDN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07250-1", "uniprot_id": "IPMK_YEAST", "id": "P07250-1", "name": "Inositol polyphosphate multikinase", "aln": "-----------MDTVN-------------------NYRVLEHKAAGHDGTLTDGDG---------LLIFKPAFPQELEFYKAIQVRDVSR-----------------------------------------RKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGD--------------------AALLKIDERLSDSTDNLDSIPVKS-------------------------------------------------------------------------------------------EKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WELLNDVDKLMRDDFID--------------------------------------------------------------------------------------------------------------------------DDDDDDDNDDDDDDDAEGSSEG-------------------------------------------------PKDKKTTGSLSSMSLIDFAHSEITP--------------GKGYDENVIEGVETLLDIFMKF------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . . . : * * . *. . . . :* **:: * * *:*:*:* :. ** ** : :*. : **: * :: :**. . . .: :::* * . : : .: : . .: :.***::*** :.: .. . . . . . .: :***** * . : *:. * :: .: ", "identical_positions": 38, "similar_positions": 71, "identity": "4.13%" }, { "cls_id": "homologset.agr.SGD:S000002582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYD4-1", "uniprot_id": "A0ABK0LYD4_RAT", "id": "A0ABK0LYD4-1", "name": "", "aln": "MAAASLQLRLT-------LYPGARGLRTFS------SVARPAAPRAGP--LSRG--------ERPMRRK--ALPPRTEKMETD----QDWPSVYPTAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNVELLK--IPNFLHLTPVAIKRHCGALKD-------FCTEWPAALDSDEKCEKHFPVEIDTADYVSSGPSIRNPRARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKTTDVLTIKTDRCPLKRQNYDYAMYLLTVLYHESWKTEEWEKNKTEEDMDEYVWAKSSSENSVLQTLLQMRAAESSVAPSREELLGTKEVEDYQKCVVRLKNEGENEASLAQYKESVKRLLNLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJZ4-1", "uniprot_id": "RT35_MOUSE", "id": "Q8BJZ4-1", "name": "Small ribosomal subunit protein mS35", "aln": "MAAAALQLRQS-------LCPGPRVLRTFS------SVASPAAPRAGPRTASRS--------ERPMRRK--ALPPRTEKMDTD----QDWPSVYPTAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNLELLK--IPNFLHLTPVAIKRHCAALKD-------FCTEWPAALDSDEKCEEHFPVEIDTADYVSSGPSIRNPKARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKATDVLTITTDRCPLKRQNYDYAVYLLTVLYHESWKTEDWENSKTEEDMDEYVWAKSSSENSVLQTLLQMRAAESSVAPSREELLGTKEVEDYQKCVVRLKNEGENEASLAQYKESVKRLLNLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82673-1", "uniprot_id": "RT35_HUMAN", "id": "P82673-1", "name": "Small ribosomal subunit protein mS35", "aln": "MAAAALPAWLS-------LQSRARTLRAFS------TAVYSATPVPTPSLPERTPGN-----ERPPRRK--ALPPRTEKMAVD----QDWPSVYPVAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNLELLK--IPNFLHLTPVAIKKHCEALKD-------FCTEWPAALDSDEKCEKHFPIEIDSTDYVSSGPSVRNPRARVVVLRVKLSSLNLDDHAKKKLIKLVGERYCKTTDVLTIKTDRCPLRRQNYDYAVYLLTVLYHESWNTEEWEKSKTEADMEEYIWENSSSERNILETLLQMKAAEKNMEINKEELLGTKEIEEYKKSVVSLKNEEENENSISQYKESVKRLLNVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q498P2-1", "uniprot_id": "RT35_DANRE", "id": "Q498P2-1", "name": "Small ribosomal subunit protein mS35", "aln": "MAASVSHPALSSFHKISCNITGISGLISFSRRISVSSVLPTSAVAAKRDAAGKGVRG-----QMKPRRQ--AGEPRTERMAVD----QDWTAVYPTAASFKPSAVPLPVRMGYPVNRGVPPAKHGNLELIK--IPNFLHLTPATIKKHCEALKP-------FLTEWPSALDSDEKCTEHFPIQVQSKDFVSSGLSLRNPDARIVTLKVKHSSLNLDDHARKKMIKLAEKRYCKETDTLTITTDSCPLRQQNYDYAMYLLTVLYHESWKSEAWEQEKTRADMEEYEWQDSPSQRNILETLKSIRGTEET-----HELLDQPEVGEYRNSVTQMKNHGETEENLLRYKEAVKKLLQL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZX6-1", "uniprot_id": "Q9VZX6_DROME", "id": "Q9VZX6-1", "name": "", "aln": "MSSALTRLLER---LPLKKQTAQSGIRVFSNQEQRQEIEDDEEFRVLSLRTVKQQMQ-----KRQQVRRDPITPPRTGRMAVD----QDWTAVWPGPRSFHPASVPLPLRQGFTERGAAAPSKFANAELMK--IPNFLHLTPPAIRQQCEAIKK-------FCTPWPKGLETEAKWQRHFPLEVTTTDYCQSLPTIRNPEARRVTITLKLSDLKFDAHARDKFLRLVGDRYNKDTDLVTFVTDRCPQKKQNYDYALYLLTACYHESFVTEPWEATKSEADMEVYLFERNQS-KVSAEGILNWNAKKGAP-----KVVPSK---SFAECVEKLINEGENEYNLGKYKEEVKKMLNIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03976-1", "uniprot_id": "RT24_YEAST", "id": "Q03976-1", "name": "Small ribosomal subunit protein mS35", "aln": "MKVPLGLWKVS----RGNLWSTQKRVLTMSRCLNSDAGNEAKTVREGPAFSADLYMHPEKWKGLPPQRILELYWERMARLGSEYKPNKDELNALLTTSEYSNVPVNDIKKLYHRGEQGAIDIKGGNVNRDNSLRPFMFDELPSQAQELVAQHREQRFYNRLAAYELPLLAQYRQEYKRPSPESHPVTYRYTSYVGEEHPNSRKVVLSVKTKELGLEEKSLHKFRILARSRYDHTTDIFKMSSDKFEHASQNARYLHDILQRLLAESKDLTEDDFSDVPLDTRHTIAKSLRKKKRDYEFPEHWKRPEDAP---------------------------------KKKFDIVDQLLSTL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : :* * * :: : :* . . : .* : . . .. * .* : : * ::. * :. : * : : . * . * .:* :* *.: :* ..* :: :: .*: *. .** : ** ..: :* ** * :* ** : . * . . : . : : : *.::*. ", "identical_positions": 34, "similar_positions": 65, "identity": "9.55%" }, { "cls_id": "homologset.agr.SGD:S000002583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8F5-1", "uniprot_id": "TADA3_RAT", "id": "Q4V8F5-1", "name": "Transcriptional adapter 3", "aln": "--------------------------------------------------------------------------------MSELKDCP--LQFHDFKSVDHMKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRR--LRVLEAETQILTDWQD-----KKGDRRILKLARDH-------------------ELGAPPKHG------------------KPKKQKLEGKTGHGPGPGPGRPKSKNVQPKIQEYEFTDDPIDVPRI---------------------PKNDAPNRFWASVEPYCADITSEEVRTLEELLKP---------PEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAVADKKKGLIG-PLTELDTKDVD------ALLKKSEAQHEQPEDGCPFGALTQRLLQ---------------------------------ALVEENIISPMEDSPIPDMSGKESGADGASTSPRNQNK---PFSVP-HTKSLESRIKEELIAQGLLE----------SEDRP--AEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKD--------QAWKTLKERESILKLLDG-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0L9-1", "uniprot_id": "TADA3_MOUSE", "id": "Q8R0L9-1", "name": "Transcriptional adapter 3", "aln": "--------------------------------------------------------------------------------MSELKDCP--LQFHDFKSVDHLKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRR--LRVLEAETQILTDWQD-----KKGDRRFLKLGRDH-------------------ELGAPPKHG------------------KPKKQKLEGKTGHGPGPGPGRPKSKNVQPKIQEYEFTDDPIDVPRI---------------------PKNDAPNRFWASVEPYCADITSEEVRTLEELLKP---------PEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAVADKKKGLIG-PLTELDTKDVD------ALLKKSEAQHEQPEDGCPFGALTQRLLQ---------------------------------ALVEENIISPMEDSPIPDMSGKESGADGASTSPRNQNK---PFSVP-HTKSLESRIKEELIAQGLLE----------SEDRP--AEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKD--------QAWKTLKERESILKLLDG-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75528-1", "uniprot_id": "TADA3_HUMAN", "id": "O75528-1", "name": "Transcriptional adapter 3", "aln": "--------------------------------------------------------------------------------MSELKDCP--LQFHDFKSVDHLKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRR--LRVLEAETQILTDWQD-----KKGDRRFLKLGRDH-------------------ELGAPPKHG------------------KPKKQKLEGKAGHGPGPGPGRPKSKNLQPKIQEYEFTDDPIDVPRI---------------------PKNDAPNRFWASVEPYCADITSEEVRTLEELLKP---------PEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAVADKKKGLMG-PLTELDTKDVD------ALLKKSEAQHEQPEDGCPFGALTQRLLQ---------------------------------ALVEENIISPMEDSPIPDMSGKESGADGASTSPRNQNK---PFSVP-HTKSLESRIKEELIAQGLLE----------SEDRP--AEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKD--------QAWKTLKERESILKLLDG-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY21-1", "uniprot_id": "TADA3_DANRE", "id": "Q7SY21-1", "name": "Transcriptional adapter 3", "aln": "--------------------------------------------------------------------------------MSELKDCPP-LKYYDFKPVDHVKVCPRYTAVLSRSEDDGIGIEELDTLQLELETLLSSASRR--LRALEEQRQILTDWQD-----KKGDKRFLKLEKDP-------------------DLAASSRHS------------------KPKKQKLDVKGSHGPGPGPGRPKSKNIQTKVQDFEFEVDPQDIPRN---------------------PKNDAPNRFWASVEPYCADITNEEIRVLEELLKA---------PDDEAEYYKIPTLGKHYSQRWAQEDLLEERREGARAN---DKKKSMMG-PLSELDAKDVD------ALLKKSESQHEPPEDGCPFGPLSQRLLQ---------------------------------ALVEENIISPMEDSPIPDIPGKD---DGAGTSPRSQGK---AFSVP-HTRSLEARIREELVSQGLLD----------SDERQGVGGESEDEVLAELQKRQAELKALTAHNRSRKLELLKLAREEMRKQELRQRVRVADNEVMEAFRRIMAARQKKRTPTKKEKD--------QAWKALKERESILKLLDG-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHZ1-1", "uniprot_id": "M9PHZ1_DROME", "id": "M9PHZ1-1", "name": "", "aln": "-----------------------------MSANLKNIKLAHFSGSLGSGGFGISASSGGAGKLPTNGTGGGKSAPTSTFLDSEVLATPGGVVIPIIRTRDVPKLLPTIAAALQRPADDHLAAEDLDAVQLELEQMLSNVALR--TRVLKAEYDSLDKDEK-----RQDRRKLDRVPGSPPCPASMLNGLLGIGSNSSTSLGSPLGGGGASSSSQSKRKRDEPTGVRKKHSSMTILKQQGVSGGTSKHQAKNSPLVVHTDDSMDYLPTLAAANASGSVLPHHQPLPQLPKMTVPKNDTPNKFWLSVEPYCMPLTNEDLRLIDDLLEQ---------YWG-PLVPPVPPLGPHYSTVWAQEDIKALQPGGARIKS--NNSSGMLK-KAEGMVDESIT------GPLTQRLVSALMEES-----LMTLPSEQ---------------------------------AAVGEHSNSTTSSSNENTHSHSSSSANAAAAAASGNFR---SLAMMKHGVGIEQRLKKTLIENGLID----------ASEFA--AHEDVDEVLMEIKRVTTEISTISQFNSEELKRLRAVASEEIKRIAIKQKLDMVDQEILECYKRMLQYRAKRKGHTIEEKQ--------EILRLTNEQRLLADQLERMQMHLPCIGGSGNSL-LEPKMXDRSLAWGWCQLMAMHQAKRQVRDASLKLQCV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32494-1", "uniprot_id": "NGG1_YEAST", "id": "P32494-1", "name": "SAGA complex subunit NGG1", "aln": "MPRHGRRGKLPKGEKLPKKEGGDNTPSKLLSSMLKTLDLTFERDIGMLNGKSVRSIPNKKTLLELQSQLDSLNEILGTIARGDQETIEALRKIRDSKNEKQANDEKQETSNADGQHESSTATEETNIIDKGVQSPPKPPPSNEISGTIENDVESIKQAADNMAKEEINEDKDLQVHRDQPREKRPFDSETENRATENENTQRPDNKK---QKIDVDKMENDPTVKNPKSEFVVSQTLPRAAAALGLFNEEGLESTGEDFLKKKYNVASYPTNDLKDLLPGELPDMDFSHPKPTNQIQFNTFLAFVENFFKDLSDDNLKFLKMKYIIPDSLQFDKTYDPEVNPFIIPKLGPLYTDVWFKDENDKNSAYKKPSPYSNDASTILPKKSANELDDNALESGSISCGPLLSRLLSAVLKDDNDKSELQSSKIIRDGGLPRTGGEDDIQSFRNNNNDTVDMTLSQENGPSVQTPDNDIDEEASFQAKLAENKGSNGGTTSTLPQQIGWITNGINLDYPTFEERLKRELKYVGIYMNLPKDENNPNSDDPDWVTGREDDEISAELRELQGTLKQVTKKNQKRKAQLIPLVERQLAWQEYSSILEDLDKQIDQAYVKRIRVPKKRKKHHTAASNNVNTGTTSQIAQQKAANSSLKSLLDKRQRWINKIGPLFDKPEIMKRIPNESVFKDMDQEEDEDEADVFAQNTNKDVELN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . : :: :. . *: : :: :: . . . .:: : : : . . . . : :: . . . . * . : . . . : :. . .:: * * ** : ::.:::: :. :* ** *: * ::: : .. : : : : . * . . :. : : . * . ..: .. :.. ::. : . .: . :* *::. * *: :.: . **: *::. :. :: * . * :. .:: . : *::: :.: : : *:: .: : : . : . *: ", "identical_positions": 25, "similar_positions": 138, "identity": "3.55%" }, { "cls_id": "homologset.agr.SGD:S000002584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61087-1", "uniprot_id": "UBE2K_MOUSE", "id": "P61087-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "---------------------------------------------------MANIAVQRIKREFKEVLK--------------------SEETSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61086-1", "uniprot_id": "UBE2K_HUMAN", "id": "P61086-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "---------------------------------------------------MANIAVQRIKREFKEVLK--------------------SEETSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A356-1", "uniprot_id": "A0A8I6A356_RAT", "id": "A0A8I6A356-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "LLFFFWFFFSELGTELRALRFLGKCSTTELNPQPRLLLLYVTGAIVTDFISLSCIPSLHYRSRAEEVAQWLQCWLLKCGELSSDLKHSCKSQTSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52486-1", "uniprot_id": "UBCD4_DROME", "id": "P52486-1", "name": "Ubiquitin-conjugating enzyme E2-22 kDa", "aln": "---------------------------------------------------MANMAVSRIKREFKEVMR--------------------SEEIVQCSIKIELVNDS-WTELRGEIAGPPDTPYEGGKFVLEIKVPETYPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAYQFKDKYDLFLLTAKHWTNAYAGGPHTFPDCDSK-----------IQRLRDMGIDEHEARAVLS---------KENWNLEKATEGLFS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21734-1", "uniprot_id": "UBC1_YEAST", "id": "P21734-1", "name": "Ubiquitin-conjugating enzyme E2 1", "aln": "--------------------------------------------------------MSRAKRIMKEIQA--------------------VKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNVEESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDPNDNNTANRIIEELLK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*: .: *.:::*.:. .*:* : ***.******:: ::*::* ***:***::* *:::*****************: *:..:**::.*:****** :.**:***** ** :: . : * ** *:. **. . . . : *:.: *::.. .* ... : * *:. ", "identical_positions": 71, "similar_positions": 66, "identity": "24.32%" }, { "cls_id": "homologset.agr.SGD:S000002585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCT8-1", "uniprot_id": "DHSD_RAT", "id": "Q6PCT8-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLLKLGVLCSGQ---------GARALSLR-SRAVRPAFVSAFLQDQPTPGWRGTQHIHLSPSHQ--SGSKAASLHWTSERVVSVLLLGLIPAGYLNP---CSVVDYSLAAALTLHSHWGIGQVVTDYVH----GDALQKATKAGLLAVSALTFAGLCYFNYHDVGICRAVAMLWKL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXV1-1", "uniprot_id": "DHSD_MOUSE", "id": "Q9CXV1-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLLKLGVLCSGQ---------GARALLLR-SRVVRPAYVSAFLQDQPTQGRCGTQHIHLSPSHH--SGSKAASLHWTSERVVSVLLLGLIPAGYLNP---CSVVDYSLAAALTLHSHWGLGQVVTDYVH----GDTLPKAARAGLLALSALTFAGLCYFNYHDVGICRAVAMLWKL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14521-1", "uniprot_id": "DHSD_HUMAN", "id": "O14521-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLWRLSAVCGAL---------GGRALLLR-TPVVRPAHISAFLQDRPIPEWCGVQHIHLSPSHH--SGSKAASLHWTSERVVSVLLLGLLPAAYLNP---CSAMDYSLAAALTLHGHWGLGQVVTDYVH----GDALQKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWKL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FN7-1", "uniprot_id": "DHSDB_DANRE", "id": "Q68FN7-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial", "aln": "--MAALVRISSLCHR----------GVSPLLFRPSSLIRPLAVQ---QKDHDCSYLISARIHATPSNYAGSGSKAATMHWTGERILSIALLSLAPVAYFCP---SPAVDYSLAAALTLHGHWGLGQVVTDYVH----GDAKIKMANAGLFVLSTVTFAGLCYFNYHDVGICKAVALLWSK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGM2-1", "uniprot_id": "DHSDA_DANRE", "id": "Q6DGM2-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial", "aln": "--MASLIRLSSVWQR----------GMRPVLLCHTQLSRGSACPRIGDVDYTEP---AGRIHTASSST----GISASQHWTGERVMTLVLLGMAPAAYLCP---GPVVDYSIAAALTMHGHWGIGQVLTDYVH----GEVKIKLAKVGIFLLSTATFFGLCYFNYNDVGLCKAVVMLWQK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCI5-1", "uniprot_id": "DHSD_DROME", "id": "Q9VCI5-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "MSLSLLLRGAVRCNAANLVKSARITPLKSYSTLVANVQRKAVVQPLAVAKIVAPVVREISVSAPRMAS---AGSSHTLLWTVERIVSAGLLAVIPAAFIAP---SQVLDALMAISVVIHTHWGVEAMVVDYMRPSVVGNVLPKVAHIALIIISVATLGGLFYFIQNDVGLANGIKRFWAIKGKDAEKA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37298-1", "uniprot_id": "DHSD_YEAST", "id": "P37298-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MMLPRSMKFMTGRR-------IFHTATVRAFQSTAKKSLTIPFLPVLPQKPGGVRGTPNDAYVPPP--ENKLEGSYHWYMEKIFALSVVPLATTAMLTTGPLSTAADSFFSVMLLGYCYMEFNSCITDYISER-VYGVWHKYAMYMLGLGSAVSLFGIYKLETENDGVVGLVKSLWDSSEKDNSQKIEAKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : * *::.: :: : ... : . . * :: : : : . :.**: . * : : *. :: *: : .: *: : :* ", "identical_positions": 10, "similar_positions": 40, "identity": "5.18%" }, { "cls_id": "homologset.agr.SGD:S000002586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU52-1", "uniprot_id": "D3ZU52_RAT", "id": "D3ZU52-1", "name": "", "aln": "MQQWEASGGTAPVTGRRRQKSAGRRSDHGSLTTCRQALGGRDIGEENRVGGDRSQDQRMAGEQ--KPSSNLLEQFILLAKGTSGSALTTLISQVLEAPGVYVFGELLELANVQELAEGANAAYLQLLNLFAYGTYPDYIANKESLPELSAAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIQKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHHRTQQQVEAEVSNIKKTLKAT----ASSSAQEMEQQLAER-ECPPHTEQRQPTKKMSKVKGLVSSRH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BV13-1", "uniprot_id": "CSN7B_MOUSE", "id": "Q8BV13-1", "name": "COP9 signalosome complex subunit 7b", "aln": "----------------------------------------------------------MAGEQ--KPSSNLLEQFILLAKGTSGSALTTLISQVLEAPGVYVFGELLELANVQELAEGANAAYLQLLNLFAYGTYPDYIANKESLPELSVAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHHRTQQQVEAEVSNIKKTLKAT----ASSSAQEMEQQLAER-ECPPHTEQRQPTKKMSKVKGLVSSRH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Q2-1", "uniprot_id": "CSN7B_HUMAN", "id": "Q9H9Q2-1", "name": "COP9 signalosome complex subunit 7b", "aln": "----------------------------------------------------------MAGEQ--KPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGANAAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKAT----ASSSAQEMEQQLAER-ECPPHAEQRQPTKKMSKVKGLVSSRH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UBW8-1", "uniprot_id": "CSN7A_HUMAN", "id": "Q9UBW8-1", "name": "COP9 signalosome complex subunit 7a", "aln": "----------------------------------------------------------MSAEV--KVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V8Z9-1", "uniprot_id": "G3V8Z9_RAT", "id": "G3V8Z9-1", "name": "", "aln": "---------------------------------------MGCTCSRKLEARAPHQGAAMSAEV--KVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELADSDFASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIAQTLQEWCVGCEVVLSGIEEQVSRANLHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZ04-1", "uniprot_id": "CSN7A_MOUSE", "id": "Q9CZ04-1", "name": "COP9 signalosome complex subunit 7a", "aln": "----------------------------------------------------------MSAEV--KVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEARNLPPLTDAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIAQTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPASGTNQRQPSKKASKGKGLRGSAKIWSKSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V4S8-1", "uniprot_id": "CSN7_DROME", "id": "Q9V4S8-1", "name": "COP9 signalosome complex subunit 7", "aln": "----------------------------------------------------MTQDMLLGNEEPSKSKETFLEKFCVLAKSSTGAALLDVIRQALEAPNVFVFGELLAEPSVLQLKDGPDSKHFETLNLFAYGTYKEYRAQPEKFIELTPAMQKKLQHLTIVSLAIKAKSIPYALLLSELEIDNVRHLEDIIIEAIYADIIHGKLFQNTRILEVDYAQGRDIPPGYTGQIVETLQAWVNSCDSVSNCIEMQIKYANAEKSKRLINKERVEQDLINLKKVLKSQ-----TSDSDESMQIDTHGPGTSGGLGQSELRKKPSKLRNPRSAAVGLKFSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03981-1", "uniprot_id": "CSN9_YEAST", "id": "Q03981-1", "name": "COP9 signalosome complex subunit 9", "aln": "------------------------------------------------------------------------------------MVMREETIKSLEDPYKYHY--------KEEWLNTKDPDEQQLFEIFAFGNIKDLPEN----IILTSLMRSKLEKLTLVTLSEIYNELSYELIKEECQIE-----DDGIIESHLIQLQN-------------------IFKAEMDSVSKSMKFSRRFDCRDVYCHEKELTIIKNPRVTKEYLVQNLRSWETKLKQNILE-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ** * : : : : . . : :**:*. : : *: :.**.:*::*:*: : :.* :: . : :* :**: :: . * . : .::: * :: : : : :.:. ::*: : ", "identical_positions": 19, "similar_positions": 56, "identity": "5.67%" }, { "cls_id": "homologset.agr.SGD:S000002588", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0J4-1", "uniprot_id": "A0A0G2K0J4_RAT", "id": "A0A0G2K0J4-1", "name": "Nipped-B protein", "aln": "-MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLP--ATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQN-------RYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAG-YMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSAMRNAASFPLRSPQPVCSPAGSDGTPK-GSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQ-EDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRSLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAG----------------GATGGNRPASQETGSTGNG-SRPALMVSIDLHQAGRADSQASLTQDSDNIKKPEETKQCNDAPISVLQEDSVGSLKSIPENHPETPKNKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESK----------------LETKTETQTEELKQSENKTTESKQSESAVVEPKQNENRLCDTKPNDNKQNNTRSENTKAR---------PETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRKDSGKPSTEKKPDVSKHKQDIKSDSSRLKSERAEALKQRPDGR-----------------------------------SESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRN-----------------------EHSTKSDGSKTEKLERKHRHESGDSRDRPS--------------GEQKSRPDSPRVKQ----GDTNKSRP---GFKSPNSKDDKRTEGNRSKVDSNK--AHTDNKAEFPSYLLGGRSSALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSLKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFS--RYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNK-------------KVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLS-LLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQ-GSIERILK-------------------QVSGGEDEIQQLQKALLDYLDENT-ETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQ--------------------------KDEESSDGAHHAKEIETTG--------QIMHRAESRKRFLRSIIKTT----PSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEE------GIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEE-----DSSYKPVKKACTQLVDNLVEHILKYEESLAD--SDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNS----KVNIKDKVLELLMYFTKH-SDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQ-----ADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFR------QDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRK------------------------------------------ERKTSPAKENESSESEEEVCRPRKSRKRVDSE--SDSDSE---DDVNSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVR--------QYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSP--KNNPAADTEDEE--SDGEDRGGGTSGSLRRSKRNSDSTELA-AQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KCD5-1", "uniprot_id": "NIPBL_MOUSE", "id": "Q6KCD5-1", "name": "Nipped-B-like protein", "aln": "-MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLP--ATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQN-------RYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAG-YMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPK-GSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKIKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQ-DDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAG----------------GATGGNRPASQETGSTGNG-SRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEETKQCNDAPISVLQEDIVGSLKSIPENHPETPKKKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESK----------------LETKTETPTEELKQNENKTTESKQSESAVVEPKQNENRPCDTKPNDNKQNNTRSENTKAR---------PETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRRDSGKPSTEKKPDVSKHKQDIKSDSPRLKSERAEALKQRPDGR-----------------------------------WESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRN-----------------------DHSTKSDGSKTEKLERKHRHESGDSRDRPS--------------GEQKSRPDSPRVKQ----GDTNKSRP---GFKSPNSKDDKRTEGNRSKVDSNK--AHTDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFS--RYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNK-------------KVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLS-LLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQ-GSIERILK-------------------QVSGGEDEIQQLQKALLDYLDENT-ETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQ--------------------------KDEESSDATHHAKELETTG--------QIMHRAENRKKFLRSIIKTT----PSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEE------GIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEE-----DSSYKPVKKACTQLVDNLVEHILKYEESLAD--SDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNS----KVNIKDKVLELLMYFTKH-SDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQ-----ADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFR------QDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRK------------------------------------------ERKTSPAKENESSESEEEVSRPRKSRKRVDSE--SDSDSE---DDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVR--------QYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSP--KNNTAADTEDEE--SDGEDRGGGTSGSLRRSKRNSDSTELA-AQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6KC79-1", "uniprot_id": "NIPBL_HUMAN", "id": "Q6KC79-1", "name": "Nipped-B-like protein", "aln": "-MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLP--ATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQN-------RYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAG-YMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPK-GSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTLRLSRVRSSDMDQQ-EDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAG----------------GATGGNRPASQETGSTGNG-SRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENK----------------LETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSR---------PETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSV---------------------------------SESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRN-----------------------EHGIKSDSSKTDKLERKHRHESGDSRERPSS-------------GEQKSRPDSPRVKQ----GDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNK--AHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFS--RYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNK-------------KIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLS-LLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQ-GSIERILK-------------------QVSGGEDEIQQLQKALLDYLDENT-ETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQ--------------------------KDEESSEGTHHAKEIETTG--------QIMHRAENRKKFLRSIIKTT----PSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEE------GIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEE-----DSSYKPVKKACTQLVDNLVEHILKYEESLAD--SDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNS----KVNIKDKVLELLMYFTKH-SDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQ-----ADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFR------QDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRK------------------------------------------ERKSSPSKENESSDSEEEVSRPRKSRKRVDSD--SDSDSE---DDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVK--------QYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSP--KNNTAAETEDDE--SDGEDRGGGTSGSLRRSKRNSDSTELA-AQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBY1-1", "uniprot_id": "NIPLB_DANRE", "id": "F1QBY1-1", "name": "Nipped-B-like protein B", "aln": "-MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLP--ATTTKSLLYNGRIAEEVSCLLSRRDDALVSQLAHSLNQVSTEHIELKDNLGSDDPEGDVPLLLQTVLSRNPNVFREK------------SLMQQPMIPSYKMPQNSMHGSPASN-YQQTTITPSPPSRYVQTQAGSGSRYMPQQNSPVPSPYAPQSPAG-YMQYSHPPSYPQHQPIQQVSVSSPIVPSGMRNIHDNKVSGQVSGNSN----HNARHCSSDEYINIVQRLGNDEGDPAMRN--TSFPVRS---ACSPAGSEGTPKVGPRPPLILQS-PPPYTSPSDTAPDLLLDSPERKKKQ----KRLLKEEGG--KGAMYGIVSSPSKDSTKLTIKLSRVKSSETEQSAEPVVPVVDHGSDAENEVSCNSLSY---------HRNPQERLSAGQCLSGEQ----SAYQQVPVLQNIGALAAKQP----------GVVSGTPYDEAELDALAEIERIERESAIERERCSKEVQDKDKPLKKRKQDSYPQEPGAAGTAG-ASGTPGVGGGCNAGNKLVPQEACAASNGSSRPALMVSIDLQQAGRVEGPVDSCPVPATEAQRWTEDGSESTGVLRLKSKTDGEVQRTVDGRPEVIKQRVETTPQKTAVDGRPETPINKHENRREISNKVSSEKRSDLSKHRHDGKAEKIRAEGKGHETSRKHEGRSELSRDCKEERHREKDSDSSKGRRSDTSKSSRVEHNRDKEQEQEKVGDKGLEKGREKELEKGRDKERVKDQEKDQEKGRDKEVEKGRYKERVKDRVKEQEKVRDKEQVKGRDKKRSKDLEKCREKDQDKELEKDREKNQDKELEKGREKDQDKELEKGREKDRDKEMEKAREKDQDKELEKGREKDQDKELEKGQEKDRDKVREKDRDKVRDKDRDKVREKDRDKVREKDRDKLREKDREKIRERDRDKGREKDRDKEQVKTREKDQEKERLKDRDKEREKVRDKGRDRDRDQEKKRNKELTEDKQAPEQRSRPNSPRVKQEPRNGEESKIKPERSVHKNSNNKDEKRGGENKNQLDGHKPQSIDSKTADFPNYLLGGKSSALKNFVIPKLKRDKEGNVMQEVRIELFS-EPRVKLEKLDLVEDLNKGAKPVVVLKKLSIDEVQKMIS--NSRSSKS---SRSSHGR------------------FRETDSRLPLCERVKMNKRRRSSTNEKPKYAEVSSDDDSSSS--VEIAPKRSKKDRDKTWEYEEKDRRGSGDHRR---SFDSRRSSG-GRHRERSPEDSDED--SPPPSLSDLARKLKKKEKQKKRKAYEPKLTVDEMMDSSTFKRFTTSVDNILDNLEDVDLTSL-DDDEIPQELLLGKHQLSELSSESAKIKAMGIMHKITHDKMVKVQSILEKNIQDGAKLSTLMNHDNDRDDEERLWRDLIMERVTKSADACLTALNIMTSARMPKAVYIEDVIERVVQYTKFHLQNTLYPQYDPVYRVDHHGGGTLSSKAKRAKCSTHKQRVTVMLYNKVCDIISNLSELLEIQLLTDTTILQISSLGITPFFVENVSELQLCAIKLVTAVFS--RYEKHRQLILEEIFTSLARLPTSKRNLRNYRLNSSDVDGEPMYIQMVTALVLQLIQCVVNLPS---DKDSDEENDR-------------KVDHDVLITNSYETAMRTAQNFLSVFLKKCGSKQGEDDYRPLFENFVQDLLSTVNKPDWPAAELLLS-LLGRLLVHQFSNKQTEMALRVASLDYLGTVAARLRKDAVTSKMDQ-RSINRILG-------------------ENSGS-DEIQQLQKALLNYLDENV-ETDPFLLFARKFYLAQWYRDTSTETEKAMKSQ--------------------------RDDDSSDGPHHAKDVETTS--------EILQKAEARKKFLRSVIKTT----ASKFSSLRVNSDTVDYEDSCLIVRYLASMRPFAQSFDIYLTQILRVLGESAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLSRPQLTEQYYDMLIERILDTGISVRKRVIKILRDICLEQPTFNKVTEMCVKMIRRVNDEE------GIKKLVNETFQKLWFTPTPNHDKEAMTRKILNITDVVAACRDSGYDWFEQLLQNLLKSEE-----DASYKPARKACAQLVDSLVEHILKYEESLAD--CENKGLTSNRLVACITTLYLFSKIRPHLMVKHAMTMQPYLTTKCNTQSDFMVICNVAKILELVVPLMDHPSESFLTTIEEDLMKLIIKYGMTVVQHCVSCLGAVVNRVTHNYKFVWSCFNRYYGALSKLKMQHQEDPNSTVLVSNKPALLRSLFTVGALCRHFDFDQEEFKGSN----KVVIKDKVLELLLYFTKN-DDEEVQTKAIIGLGFLFIQDPGLMFVTEVKNLYNTLLADRKTSVNLKIQVLKNLQTYLQEEDSRMQE-----ADREWNKLSKKEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSSVRHYALNVIALTLNQGLIHPVQCVPYLIAMGTDSEPTMRNKADQQLVEIDKKYTGFIHMKAVAGMKMSYQVQQAIVGSKDTVIRGFR------LDESSTALCSHLYTMVRGNRQHRRAFLISLLNLFDDNTKSDVNMLLYIADNLASFPYQTQEEPMFIMHHVDITLSVSGSNLLQSFKESLLKEPRKVEVVKKKKKKKKKKKQK-----QKRGKKYGSEEEDESSRSSSSSSSSSSSSSDSDSSEEEVIHRRKKPRRTTAN--SDSDSDLDVEDVDKVMLRLPDNPEPLLDFANASQGILLLLMLKQHLKNLYGFSDSKIQKYSPTESAKIYDKAVNRKANVHFNPRQTLDYLTNSLSNSDLSNDVKRRVVR--------QYLDFKVLMEHLDPDEEEEEGEASASSHARNKAINALLGGSSP---KNNAAESYDDD--SEVEEK---TPGSSRRSRRTGDSAEAS-GHRNETVEATDVIALCCPKYKDRPQIARVIQKTSKGYSIHWMAGSYSGTWAEAKKRDGRKLVPWVDTIKESDIIYKKIALTSAHKLSNKVVQTLRSLYAAKEGSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F5HSE3-1", "uniprot_id": "NIPLA_DANRE", "id": "F5HSE3-1", "name": "Nipped-B-like protein A", "aln": "-MNGDMPHVPITTLAGIAGLTDLLNQLPLPSPLP--GTTTKSLLYNGRVAEDVGHLLGCRDETLVSQLANSLSQVSTEHIELKDSLGSDELEGDVPVLLQLLMSRNPNIFRNKTAPNTPQYPAQAGISQQSMAPPYKITHGSMQGSPASANYQQASMSHSPSGHFVPGQSGPGGRFLPQQGSPVPSPYAPQSPATGYRQYPHPPAYSQHQHLQQGSVASPMIPGAMRNVHENKDQ---------------------------MRMG-------------------------------------FTSHLLQS-SPPYTPPCDGTKDLHLGSQDKQRGQ----KSSEGEQDSPDKATVYDIVGSPAKDHTKLILRPSRARPAEVELG--------------------------------------------------------------------------------------GMYPGSDPEGELVEALAAIERMESEAAMETERSAKEVQDKDKPLKKRKQDSHPQEPGAAGTAGSGSGAPGGGGGANAGHRLAPQEASAAGTSASRPGLQVS--LEQAGRVEDDCMGMPIPASEAQRWPQEPQE------------------------------------------------------------------------------------------------------------------------GVTPKAVKHEHDHDPEHP--------------------------------------------HYDD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQPDTPRQKHRPEGRHGD----------------------------------------------------------GGAQRAAVQ------SGSKQVELPPYMLGENTGVLKNFTIPKIRK---GELGGGDIPEGWK-QPCVRLERLEADVDVKKSVKPVVVLQKLSIDEVQRLMRERDSRASKSGK-NRLSSGRSGKGGIDPSVLKDLPPELLAEIESTMPLCERVKMNKRKRSTVNERPKYAEDSSEDEEFS------SRKRQRKDRDRTWEAEERDRRSSGEHRRG--NFDARRGSG-SRY-----DDSDQD--SPPPSLNEVARRLKMK--QKKRKVYEPKLTPEEMMDSSTFKRFTLSIDNILENLEDVDFTAQ-DDDEIPQELLLGKQQLNELGSESAKIKAMGITSRIPSDKLVKLLNILEKNILDGASLSTLMNLDNEGEDEERLWRDLIMERVTKSADACLTALNIMTSTHMPKAVYIEDVIERVLQYTKFHLQNTLYPQYDPVYRVNPKGGSMLSSRAKRAKCSTAKQKVIIMLYNKVCDVVSNISELLEIQLMTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFS--RYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDDEGEPIYIQMVSALVLQLIQCVVHLPA---DRDS-EDDHK-------------KVDDDVFITNSYETARRTAQNFLSVFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPDWPASELLLS-LLGRLLVHQFSNKQTEMALRVASLDYLGTVAARLRKDSVTSRMDQ-KAIERIIR-------------------ENTEG-DETQRLQKALLDYMDENA-ETDPALAFARKFYIAQWFRDCTTETEKAMRSQN-------------------------QKEDDSDGAQHAKELQATG--------DIMQRAETRKKFLHSVVKST----PNQFTTLRMNSDTVDYDDACLIVRYLASTRPFSQSFDIYLTQILRVLGESAIAVRTKAMKCLSEVVAVDPSILARSDMQRGVHGRLMDNSTSVREAAVELLGRFVLSRPQLTEQYYDMLIERILDTGISVRKRVIKILRDICLEQPNFSKITEMCVKMIRRVNDEE------GIKKLVNETFQKLWFTPTPNHDKETMNRKILNITDVVSACKDTGYDWFEQLLQNLLKSEE-----DSSYKPTRKACVQLVDNLVEHILKYEEALA----EHKSVNSTRLVACITTLYLFSKIRAQLMVKHAMTMQPYLTTKCSSQSDFMVICNVAKILELVVPLMDHPSESFLTTIEEDLMKLILKYGMTVVQYCVSCLGAIVNKVTHNYKFVWACFNRYYGALTKLKVQHQEGTNSMALAATKAALLRSLFTAGALCRHFDFDLEQFKGTT----KVVIKEKVLELLLYFTNH-EDEEVKCKAIIGLGFLFIMHPSQMFVPEVKTLYNGLLSDKRSSITLKIQVLKNLQMYLQEEDTRMQE-----ADREWQKLSKQEDLKEMGDISSGMSSSIMQLYLKQVLESFFHAQSSVRHFALNVIALTLSQGLIHPVQCVPYLIAMGTDAEPTMRNKADQQLVEIDKKYTGFIHMKAVAGMKMSYQVQQAVFGSAGSVIRGFR------QDESNSAQCSHLYSMVRANRQHRRAFLISLLNLFDDSSKMEVNMLLFIADNLAYFPYQSQEEPLFIMHHIDITLSVSGSNLLQTFKESLVKIPGRKSRKRRRRRRRPQRQQPPPPPPQQQQQQNGSEEERGAQDEERERHSGDEEYDDDDYEEDEDGHRVRKPKPTEDIRQSESDSDSDLDDVDAVMERLPDDSTSLVDFARASQGILLLLVLKQHLKNLYGFSDGKIQKYSPSESAKVYDKAVNRKTLANFNPQQTIDFLRHHDVHGELTYELKRKIVK--------QFLDFKLLMEHLDPDEEDEDGDTSAN--VRNKAITALLGGAAASPRNHHTGDSEEDDERSEGEER---TPGASRRGRRTGDSADLLSANMNESVSALDIIAIHCPKYRDRPQIARVIQKNSDGYSIHWMAGSYSSTWAEAKKRDGRKLVPWVDSIKETDIIYKKITLTSGNKLNHKVAQTLRSLYAAKDRNSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLI2-1", "uniprot_id": "NIPB_DROME", "id": "Q7PLI2-1", "name": "Nipped-B protein", "aln": "MGERDNPTVPVTTLAGLTSTSDLLSELPVADSLQSAASLNKSLLFHALVANESSNLLSMRNENLVRQLVTAIERTNSDNIELIHCPVQDTATN-------------------------------CSTYPELLQGIYHFRPAVFNTSIKIHSPDQHTAN-----------ARLEAKKMQIDSYSIPECYASPTNLS--ISNEHQLQDAQACFNQLTSMTSKEILEEFSQIN--------------------------------------------------------------------------------------------------------------------FKENATEKDKIDVIENSDLNVTKILSQNTLKKKSNTPER------------------------------------------------------------------------------------------------STVQSIQEQFFIQQQEANYNLKHDLNQVSTNVGQIQNISDTFPQEPS--------------------------------------NFNLNSVNIPNMLYVQSPPFTESEP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQAHHSSIEYLK-----KKKSQILDVSILNRQQVLENTSLHIINKSSTYQTNQN------------VSTTTSTSTSSSGKSQVRVCINRLSIEDSRLMQQSIKKFVQKS-------------------------PELARSMGLLQETCQQQHENLNIIPTSAEECVLESRAS------------STNNTVKIPIDTFSTIKADEKRSAKRKLAISIGDIP--------------------------PEQIFSKPKMRRVERITPLSNTKCVKEEVTRSQTYQQFIRNMDHIIEILDDSESPNFDSEDVDETIECISSKLLNSMSTDVAKLKAKQALDSIPKNKLTLLINYAMRNVYLAR------NYFAGTEDEDEFVDDEVIEKLLNAMDACLLICNIYS-TVSDLQFLQEDNVSHIIKFTQFQLRETIFPLHDPVYTAKSIKR---TTHRKKIKSHQAQNRSMQLFYLKTVELLKVFVTLFDKCVFVDTIVLPLSTLAIEPFFVDNIETLQFVCLELVTTIFRKERYDKIRNSILGDILTSIDRLPSSKKNLRPYKLTNNGGN-----IQMVTALVLQLIQCATILPDSLCDNGKFSNKPQEGNTFDEEGKKLLQPSQDLLVLQKYDVAVSIGGNFLTTFLNKCKSRSNETDFRPLFENFIHDLLATVNKPEWPASELLLS-LLGTMLVRYVSDKGIEQSIRLVSLDYLGIVAARLRKDTVESRCRV-NIIDSMIQSIKLEQEKEGDVTSNNDQFDLEPEEQRTDFLQKILLDFLAVNAQEENLIWDYARHFYLAQWYRDVIYQRRRINDGKKGLAFRKSKIRNNRRTNGDYLDTSDSGSCDESDTDTNKKRIHCVDSNDFELNINIYKALEARKQYFINKIKPFSVFGEQNHSSNQHIKTYIDYNNAQLIAQYLATKRPFSQSFDGCLKKIILVVNEPSIAVRTRAMKCLANIVEVDPLVLKRKDMQMGVNQKFLDTAISVREAAVDLVGKFVLSNQDLIDQYYDMLSTRILDTGVSVRKRVIKILRDICLEYPDFSKIPEICVKMIRRVHDEE------GIQKLVTEVFMKMWFTPCTKNDKIGIQRKINHIIDVVNTAHDTGTTWLEGLLMSIFKPRDNMLRSEGCVQEFIKKNSEPPMDIVIACQQLADGLVDRLIELEDTDNSRMLGCITTLHLLAKVRPQLLVKHAITIEPYLNIKCHSATAAKFICAVADILEKVVPLVNNASESFLASLEEHLMLLVVSRNQAEVTSCVSCLGALVNKITHNFKLIRDCFQKFYRVLDVSRSQVIQG-NNSVDNIYTPSFRRSLFTIGILMRYFDFKSPIALGETNDGLPVSICEDVFHCLMFFCRC-TNQEIRKQALISLGSFCVLNDGYLTRSELKNLYCEILSSIANDAGFKIICMRNIWIYLTESEMFMHN-----KEKEWEKQSKHEDLKEMNDVSSGMASRIIQLYLEEILECFLNRDDTVRLWAVKVIQIVLRQGLVHPVRMVPYLICLSTDHRIESAHRADALLKDIDKTYSGFVNMKVQFGLQLCFKLQKILQINNRGKLEIIRGYASRGPDNTTTALNDFLYTLLRTTKPQRRALVQTVTKQFDDQ-KTSLQQMLYIADNLAYFPYVVQDEPLYLIHQIDLLISMAGTHLLATFKEHIKPSDKE----------------------------------------------GDVLEDDDDVEDPE-----------------------------VLFNRLPEDLTEIIKCITSAQACMLLLILKDHLKEMYAITDSKISRYSPSE-QKLYEKAVTRKSVNDFNPKTTIDVIKKQMSQEKLSTDINFTLTKEEKLDLVVKYLDFKQLMLKLDPDDGDSDADESRDKTMLNISASSDGVAFSS----------------------------SAKNSHSACDGYSLT-----------------------VTDVVDVPMSHIAKASMLTSKPSGRKTNPVRTKKKRRKIDSTDDETSDAEYA--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04002-1", "uniprot_id": "SCC2_YEAST", "id": "Q04002-1", "name": "Sister chromatid cohesion protein 2", "aln": "------------------------------------------------------MSYPGKDKNIPGRIIEALEDLPLSYLVPKDGLAA--------------------------------------LVNAPMRVSLPFDKTIFTSADDGRDVNINVLG------------TANSTTSSIKNEAEKERLVFKRPSN-FTSSANSVDYVPTNFLEGLSPLAQSVLSTHKGLN---------------------------------------------------------------------------------------------------------------------------------------DSINIEKKSEIVSRPEAKHK-----------------------------------------------------------------------------------------------LESVTSNAGNLSFNDNSSNKKTKTSTGVTMTQANLAEQYLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKNILDIVGFDQNSAEIGNIEYWLQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------NKKFVLTTNCLTKLQMTIKNITDNPQLSN--------SIEITWLLRLLDVMVCNIKFSKSSLKMGLDDSMLRYIALLSTIVLFNIFLLG------------KNDSNLHRESYIMEPVNFLSDLIESLKILTIEYGSLKIEFDTFQEALELLPKYIRNGPFLDDN-----------------------------------------VTAKLVYIFSDLLMNNDIEATTNIQFQSFWDN----VKRISSDILVSLFG--SFDQQRGFIIEELLSHIEKLPTKRIQKKLRKVGN-----QNIYITDFTFTLMSMLENINCYSFCNQMKDIAPENID-----------LLKNEYKKQEEFLFNIVEHINDTILERFFKNP------SALRYVIDNFVQDLLLLISSPQWPVTEKILSSLLKRLLSVYSPSMQVSANIETICLQLIGNIGSTIFDIKCSTRDHEDNNLIKMIN--------------------------YPETLPHFFKSFEECIAYNETIKCRRSATRFLWNLRLGTILILEEYTKDAK----------------------------------------------------EQIITVDNELKKILEQIKDG-------GLGPELENREADFSTIKLDYFSILHAFELLNLYDPYLKLILSLLAKDKIKLRSTAIKCLSMLASKDKVILSNPMVKETIHRRLNDSSASVKDAILDLVS-----INSSYFEFYQQINNNYNDDSIMVRKHVLRINEKMYDETNDIVTKVYVIARILMKIEDEEDNIIDMARLILLNRWILKVHEVLDQPEKLKEISSSVLLVMSRVAIMNEKCSQLFDLFLNFYLLNKEAHS--KEAYDKITHVLTILTDFLVQKIVELNSDDTN--------EKNSIVDKQNFLNLLAKFADSTVSFLTKDHITALYPYMVSDEKSDFHYYILQVFRCTFEKLANFKQKFLYDLETTLLSRLPKMNVREIDEAMPLIWSVATHRHDTARVAKACS----SCLSHLHPYINKANNEEAAIVVDGKLQRLIYLSTGFAR-FCFPKPSNDKIAFLQEGETLYEHITKCLLVLSKDKITHVIRRVAVKNLTKLCGNHPKLFNSRHVLHLLDKEFQSDQLDIKLVILESLYDLFLLEERKSVRNTGVNSTLSSNSILKKKLLKTNRVEFANDGVCSALATRFLDNILQLCLLRDLKNSLVAIRLLKLILKFGYTNPSHSIPTVIALFASTSQYIRHVAYELLEDLFEKYETLVFSSLSRGVTKAIHYSIHTDEKYYYKHDHFLS----LLEKLCGTGKKNGPKFFKVLKRIMQSYLDDITDLTSTNSSVQKSIFVLCTN-ISNITFVSQYDLVSLLKTIDLTTDRLKEVIMDEIGDNVSSLSVS-----------------------------------------------------------------------------------------------------EEKLSGIILIQLSLQDLGTYLLHLYGLRD-DVLLLDIVEESELKNKQLPAKKPDISKFSAQLENIEQYSSNGKLLTYFRKHVKDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : :: ::. . : . : : : : : .. . . . : : * : : :: : :: : .: : : :: : : : .: :. : . :. :.::: . . . : :. :: .:.:* : : : : : . . :* . . : . *: .::..: : : . : . : :* : . : . : .:: . .: :. : :: :. : :.: : .*: : :: . .::.::* ::: * *: :::: : :**:.: . : :: . * .: ::.::: . . :. : . . :: . .:* *::: * :::**::*** :..*:**.:* :** ** :* .. . :. .*: :* :.: : . :: : :: : * : : .: . : : :: : . .. . : : . : : . :* . . *:. * : : : :* *. *: :: : * :*: *:***: :. * :* . :: :: :: *.: **::* ::*:. . ::*: : . * .: ***:*::* ..: * : . : .::: ::.*** . *:.. : *: . .. : .: : . * .:. :: :* : .: . . . : :* : . . . :: . * *::*. : : . * : . : .::. .. : : .:.** :* *: : . . : .:. : ::..: .. :. * : : : *. : * :: : * * * : :.: . *: : . . :: *: .* . : .: * : . . : * * * . : . : * . :.: ..*:.* : :*.::*: : : . *:.:: : * * :* : :* :*.: :. : * * :: :.* :: . *: . : . : :: : . .:.: : :: : : . . . . :: :: :: :.: * : : ::: :*: . :: : : : . : * * :* .: .: * .: . * :: :* : * : :: : : .: .. : ", "identical_positions": 112, "similar_positions": 493, "identity": "3.62%" }, { "cls_id": "homologset.agr.SGD:S000002590", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC86-1", "uniprot_id": "MPPE1_RAT", "id": "B1WC86-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MALVRWGLRRQNFHLLRRRR-VLLLKLTVVVISVLLFCEYFIYYLVLFRCHWPEVKMPARGGRQ---EPVLKAMFLADTHLLGEIRG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDVFDEGKWSSAQAWADDLHRFQRMFR---------HGSHVQLKVVIGNHDIG--FHYQMSKYRINRFEKVF--GSERLFSLKG-VNFVMVNSVAMEGDGCTICSEAEAELREISRKLNCSQEQVQGSSQCDHEP--RLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERSVPFEEKYD-VLSREASQKLLWWLRPRLILSGHTHSACEVLHPGGAP------------------EVSVPSFSWRNRNNPS-----FIMGSLTSRDYALSKCYLPCEDTVLTTYCAAAAFLLVLILAHFERLPSSFLFGW--KLCRSHLRR-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XL7-1", "uniprot_id": "MPPE1_MOUSE", "id": "Q80XL7-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MALVRWGLKRQNFHPLRRRRRALLLKLTVVIISVLLFCEYFIYYLVLFRCHWPEVKTLAHGGRQ---EPVLKAMFLADTHLLGEIRG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSSDQAWADDVQRFQRMFR---------HDSHVQLKVVIGNHDVG--FHYQMSKYRIKRFEKVF--GSERLLSLKG-VNFVMVNSVAMEGDGCIICSEEEAELREISRKLNCSQE-VPGSSQCDREPEPRLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERNVPFEEKYD-VLSREASQKLLWWLRPRLVLSGHTHSACEVLHPGGAP------------------EVSVPSFSWRNRNNPS-----FIMGSLTSRDYALSKCYLPFEDTVLTMYGAAAGFLMILILVHFEHLPSPFLCGW--KLCRLHMRR-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53F39-1", "uniprot_id": "MPPE1_HUMAN", "id": "Q53F39-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MAMIELGFGRQNFHPLKRKS-SLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFR---------HPSHVQLKVVAGNHDIG--FHYEMNTYKVERFEKVF--SSERLFSWKG-INFVMVNSVALNGDGCGICSETEAELIEVSHRLNCSRE-ARGSSRCGPGP--LLPTSAPVLLQHYPLYRRSDANCSGEDAAPAEERDIPFKENYD-VLSREASQKLLWWLQPRLVLSGHTHSACEVHHGGRVP------------------ELSVPSFSWRNRNNPS-----FIMGSITPTDYTLSKCYLPREDVVLIIYCGVVGFLVVLTLTHFGLLASPFLSGL--NLLGKRKTR-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566Y9-1", "uniprot_id": "MPPE1_DANRE", "id": "Q566Y9-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MTLVFGSSCR------------LAVTLIFAFVSVFVFCEYVIYYLVILRCSWPLLEIEDS-------HSPLRALFLSDTHLLGAIRG-------HWLDKLRREWQMERAFQTSMWLLNPEVVFILGDVFDEGKWSTSQDWEDDVRRFKRIFR---------HPVDTKLVVLVGNHDIG--FHHEMTKQKLERFEQVFNVTSARILTIKG-VNFLLVNSVALHGDHCPICQHVEEELQKLSHALNCSIQGAQHNGQCKNAA--RFAPAAPVLLQHYPLYRVSDAMCTGVDTAPLDEQYLLFQERYD-VISKNASKKLLWWFKPRLILSGHTHNGCEVLHEKLYP------------------EISVPSFSWRNRNNPS-----FVLGTFSQSEFQLSKCFLPEERTVLVVYCSSCLIIALITLIHLKMFRNSLQFTN--NLIGKHKTL-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLR9-1", "uniprot_id": "MPPE1_DROME", "id": "Q9VLR9-1", "name": "Metallophosphoesterase 1 homolog", "aln": "-------------------------------MR------------FLYACFVIVLCALIFCEYVADFVVLQKCKWPEIKRKKY------VDDPLRAMILADPHLLGPHRG-------HWLDKLYREWHMTRAFQAASRLFQPDVVFVLGDLFDEGDMVSDKQFQEYVWRYLKMFH---------LPPGIPLISVAGNHDVG--FHYKMHPFFMSRFESYLNNSSVNLYTIKQ-IHFVVINSMAMEGDGCMFCTQAEDQLKNISRTLYCMKY--PLEAECARTR--RHPYSQPILLQHFPTYRISDTMCEEHDAPYIEA----FRERFH-VLSKDATDMLGELLKPRLAFAGHSHHFCHSVNRLGID------------------EYTVASFSWRNKVNPS-----FMLATITPDDYVVSKCKMLPQQFVFNSYLSAGILCLIVIGFQLRKCIQSRRQSS--AVDHRKVNYLD-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40986-1", "uniprot_id": "CDC1_YEAST", "id": "P40986-1", "name": "Cell division control protein 1", "aln": "MVYRNRSKSVLSTHSKKSDDKAHYKSRSKKKSKSRSKKRLRIYWRYISIVWILWLGLISYYESVVVKRAMKKCQWSTWEDWPEG------AESHRVGLFADPQIMDEYSYPGRPQIVNYFTRVIVDHYHRRNWKYVQYYLDPDSNFFLGDLFDGGRNWDDKQWIKEYTRFNQIFPK--------KPLRRTVMSLPGNHDIG--FGDTVVESSLQRFSSYFG-ETSSSLDAGN-HTFVLLDTISLSDKTNPNVSRVPRQFLDN--------------FAMGSHP------LPRILLTHVPLWRDPEQQTCGQLRESKEPFPIQKGHQYQTVIENDISQEILTKIQPEILFSGDDHDHCQISHSYPFQGKTKNAQEITVKSCAMNMGISRPAIQLLSLYNPSDLTMVNAGGEYASKTYQTELCYMPDPYKAIRMYLWGLLFSAAFIAYMHFFPKSFNNRVA--TIMNRVFTRPDGNTSDLPLPTSISKSKSKKSLTHSKYAVNDTRSIKQFLVNAIVLFVSVMPIFIYFYTVV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0B4LF50-1", "uniprot_id": "A0A0B4LF50_DROME", "id": "A0A0B4LF50-1", "name": "", "aln": "----------------------MASLRVVNRNR-----------LVCRGFVALTLLLVFFNEFIVYYMAQS--SWQPIDCKLDN--------CTRLLLIADPQILGNSYDRSS---HSPLARYDSDRYLAKTFERALAFTQPHIIVFLGDLLDEGNIATAQEYKQYVQRFRRIYQNKNYKKFRMISAFFQRVHVPGDNDIGGENGDYISNSNQRRFENEF--MSEDLFDYDNRLRFFKINRMLLDFSNPDRDNNADRLRIGVS--------------------------HAPLLIGGGPLLR--------AIISDLDPHIIFSGHWHESRIFIYPSTKVINFYEN-----SVRHFDLKALKEQEHS----------------YLEIMVPTCSYRMGKSKIG----LGYAVLENYNLSYTVLWQPNRFILLFTYVFWGLFVVCGFVVFKMMTRCPFRVAKRQTLYNRVSTIPQF----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : * . . * . : :::*.:::. : : : : :: :*. ..***::* * : : . *: ::: : *::*:* : **.. : : *. :: : : . . :*: * * : . .. : : : . . * . : .: . . . : * : : ", "identical_positions": 21, "similar_positions": 72, "identity": "3.95%" }, { "cls_id": "homologset.agr.SGD:S000002591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ79-1", "uniprot_id": "TXND9_MOUSE", "id": "Q9CQ79-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEGNGSVDMFSEVLENQFLQAAKLVEN--------HLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLS----KGHGEYREIGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKLNVEKAPFLCERLRIKVIPTLALLRDGKTQDYVVGFTDLGN-TDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K581-1", "uniprot_id": "TXND9_RAT", "id": "Q8K581-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEGNGSIDMFSEVLENQFLQAAKLVEN--------HLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLS----KGHGEYREIGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKPNVEKAPFLCERLRIKVIPTLALLRDGKTQDYIVGFTDLGN-TDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14530-1", "uniprot_id": "TXND9_HUMAN", "id": "O14530-1", "name": "Thioredoxin domain-containing protein 9", "aln": "MEADASVDMFSKVLEHQLLQTTKLVEE--------HLDSEIQKLDQMDEDELERLKEKRLQALRKAQQQKQEWLS----KGHGEYREIPSERDFFQEVKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAPFLCERLHIKVIPTLALLKDGKTQDYVVGFTDLGN-TDDFTTETLEWRLGSSDILNYSGNLMEPPFQNQKKFGTNFTKLEKKTIRGKKYDSD-SDDD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGV8-1", "uniprot_id": "PHLP3_DROME", "id": "Q9VGV8-1", "name": "Phosducin-like protein 3", "aln": "---------MANILENQLFTAAKTIEQ--------QLDQQLDRLDNLDSDDLKVLREQRLREMKDLNNKKQEWLR----NGHGTYTELADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAEKTPFLTQRLRIKVIPTIALVKDSKTKDFIVGFTDLGN-CDDFATEMLEWRIAHSGAIDYKGDLMQPPDVKRK----PFINRPQKTIRGG-YDSDDSDIDLDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04004-1", "uniprot_id": "PLP1_YEAST", "id": "Q04004-1", "name": "Phosducin-like protein 1", "aln": "-MEDKLDRYYTNVLSNAEKDKHTTVDSDDKSSGEENLDELLNELDRELDEDHEFLSAYRSERLQQISDHLKQVKKNVEDDGYGRLQCIDNEADAIQICTKTTMVVIHFELETFGKCQYMNEKLENLAKRYLTTRFIKVNVQTCPFLVNKLNIKVLPFVVGYKNGLEKVRYVGFSKLGNDPNGFDIRRLEQSLAHSGVIEDTFEIRKHSSVNTERFASTNHDRS---------ESD-SDLDI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*.: . ::. :**. ::.**. .:: : * * ::. .:: :: .*:* : .* : :: .:: :* ** :: :*: :: :* *: ::: ::* * *.:. *** ::*.***:* :. ::. : ***:.*** :.* . ** :. *. :: . :: : . . : . :** ** * ", "identical_positions": 42, "similar_positions": 83, "identity": "17.28%" }, { "cls_id": "homologset.agr.SGD:S000002593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAN9-1", "uniprot_id": "D3ZAN9_RAT", "id": "D3ZAN9-1", "name": "", "aln": "MRCTDVKVLRDKPPQSGPRDGGGGTAGAPPPRRRAASRRAPNSRPGPAAAAMKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGY-GRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKE------------RSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGIS---LGSYLESLMATTISSNAKKGWAAIEWII------------------EHSESAIS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE85-1", "uniprot_id": "PLD3A_MOUSE", "id": "Q8VE85-1", "name": "PRELI domain containing protein 3A", "aln": "---------------------------------------------------MKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGC-GRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKE------------RSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGIS---LGSYLESLMATTISSNAKKGWAAIEWII------------------EHSESAIS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96N28-1", "uniprot_id": "PLD3A_HUMAN", "id": "Q96N28-1", "name": "PRELI domain containing protein 3A", "aln": "---------------------------------------------------MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGR-GRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIRE------------HSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGIS---LGSYLESLMANTISSNAKKGWAAIEWII------------------EHSESAVS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZZ3-1", "uniprot_id": "E7EZZ3_DANRE", "id": "E7EZZ3-1", "name": "", "aln": "---------------------------------------------------MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTH-GRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKE------------HSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVS---LSSYLEGLMALTMSANARKGWDAIEWII------------------QNSEREKCPFV------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9CYY7-1", "uniprot_id": "PLD3B_MOUSE", "id": "Q9CYY7-1", "name": "PRELI domain containing protein 3B", "aln": "---------------------------------------------------MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPS-GKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQE------------HSVVDPVTRTMELKSTNISFTNMVSVDERLTYKPHLQDPEKTVLTQEALITVKGVS---LSSYLEGLMASTISSNASKGREAMEWVI------------------HKLNAEIEELAASARGSIRTPMAAAAALVDK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P9U4-1", "uniprot_id": "PLD3B_RAT", "id": "Q6P9U4-1", "name": "PRELI domain containing protein 3B", "aln": "---------------------------------------------------MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPS-GKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQE------------HSVVDPIRRTMELKSTNISFTNMVSVDERLTYKPHPQDPEKTVLTQEALITVKGVS---LSSYLEGLMASTISSNANKGREAMEWVI------------------HKLNAEIEELAASARGSIRTPMAAAAALVDK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3B1-1", "uniprot_id": "PLD3B_HUMAN", "id": "Q9Y3B1-1", "name": "PRELI domain containing protein 3B", "aln": "---------------------------------------------------MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDPS-GKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQE------------HSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVS---LSSYLEGLMASTISSNASKGREAMEWVI------------------HKLNAEIEELTASARGTIRTPMAAAA-FAEK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3U9-1", "uniprot_id": "SLMO_DROME", "id": "Q9V3U9-1", "name": "Protein slowmo", "aln": "---------------------------------------------------MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVVD--GVLHTHRLVQSKWYFPKWTHALIGTAKT-CFASE------------RSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVP---LSHYMEDLLTSTISTNAGKGRQGLEWVIGLINTEVKGIARGTDELLHNTRRSIDEVTESARKSMDEISAQAAKAAKAMHIT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04006-1", "uniprot_id": "UPS3_YEAST", "id": "Q04006-1", "name": "Protein UPS3, mitochondrial", "aln": "---------------------------------------------------MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELKEHGDVLLTERLITIRQNTPHWMSILVG-NTNLAYVRE------------VSTVDRRDRSLTMRSCNMTFPHILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGKVGFDSIL----------------------AMFNDIWKNANE-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8N945-1", "uniprot_id": "PRLD2_HUMAN", "id": "Q8N945-1", "name": "PRELI domain-containing protein 2", "aln": "--------------------------------------------------MGVSVDVHQVYKYPFEQVVASFLRKYPNPMDKNVISVKIMEEKRDESTGVIYRKRIAICQNVVPEILRKSLSTLVILCWKKVSILKVPNIQLEEESWLNPRERNMAIRSHCLTWTQYASMKEESVFRESMENPNWTEFIQRGRISITGVG--FLNCVLETFASTFLRQGAQKGIRIMEMLLK-----------------EQCGAPLAE--------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:: * : **** : ::...:: . . : *: . * :. : * :: : : : : :: . . * : .:.. . : :. : *: :. :* : .* ** :: :: ", "identical_positions": 15, "similar_positions": 51, "identity": "5.28%" }, { "cls_id": "homologset.agr.SGD:S000002596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61390-1", "uniprot_id": "TCPW_MOUSE", "id": "Q61390-1", "name": "Probable T-complex protein 1 subunit zeta-2", "aln": "MAAIKIANPGAEVTRSQAALAVNICAARGLQDVLRPTLGPKGALKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASIIAKVAAAQDHVTGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFDVAKTKALEVLDEIKVQK---EMKREILLDVARTSLQTKVHAELADILTEAVVDSVLAIRRPGV--PIDLFMVEIVEMRHKSETDTQLIRGLVLDHGARHPRMRKQVRDAYILTCNVSLEYEKTEVSSGFFYKTVEEKEKLVKAERKFIEDRVQKIIDLKQKVCAE-SNKGFVVINQKGIDPVSLEMLAKHNIVALRRAKRRNLERLTLACGGLAVNSFEGLSEECLGHAGLVFEYALGEEKFTFIEDCVNPLSVTLLVKGPNKHTLIQIKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNY---KHRVQGRVRLGIQAFADALLIIPKVLAQNSGYDLQETLIKIQTKHAESKE-----LLGIDLNTGEPMAAAEAGIWDNYCVKKHLLHSCTVIATNILLVDEIMRAGMSSLRD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92526-1", "uniprot_id": "TCPW_HUMAN", "id": "Q92526-1", "name": "Probable T-complex protein 1 subunit zeta-2", "aln": "MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTK---EMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGY--PIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQ-SNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTY---KNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQ-----LVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80317-1", "uniprot_id": "TCPZ_MOUSE", "id": "P80317-1", "name": "T-complex protein 1 subunit zeta", "aln": "MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQVKVSK---EMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIRKKDE--PIDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKKKVCGD-SDKGFVVINQKGIDPFSLDALAKEGIVALRRAKRRNMERLTLACGGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKY---KPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQ-----LVGVDLSTGEPMVAAEMGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZY35-1", "uniprot_id": "A0A8I5ZY35_RAT", "id": "A0A8I5ZY35-1", "name": "T-complex protein 1 subunit zeta", "aln": "MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQVKVSK---EMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIRKKDE--PIDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIVELKKKVCGD-SDKGFVVINQKGIDPFSLDALAKEGIVALRRAKRRNMERLTLACGGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKY---KPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQ-----LVGVDLNTGEPMVAAEMGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40227-1", "uniprot_id": "TCPZ_HUMAN", "id": "P40227-1", "name": "T-complex protein 1 subunit zeta", "aln": "MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSR---EMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDE--PIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGD-SDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKH---KPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQ-----LVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXQ5-1", "uniprot_id": "Q9VXQ5_DROME", "id": "Q9VXQ5-1", "name": "", "aln": "MASISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPV---EINKKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRVKKVIELKRSVCDG-TDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFEVRAYNELVAF---KDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVKLTVEDRLSPE-----LVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEVMRAGMTSLKG---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39079-1", "uniprot_id": "TCPZ_YEAST", "id": "P39079-1", "name": "T-complex protein 1 subunit zeta", "aln": "-MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVARSSLLTKVDADLTEVLTPIVTDAVLSVYDAQAD-NLDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKHNILALRRAKRRNMERLQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *. ** * ** :*: :*.***.*:...*****::****.***:**:****:*** ***** *** :**:.::***. ******: * ::****:**. ::.**:****:::**: *: ::::.*::.*: . .:: *::**.:** ***.. *:::** .:::*:: :**.*:*:::*:* .** :::***:***.*** * .::.:*::* ********:**.*****.:.:::: :. :**:*:: :::*:::** .** .:* **:********.**: ::*..*:*********:*** *. ** * **.:.* : **.:*:*:: .:**:*:*:: . :* * *:*:**..:::: * ***:******: *.: * ::*****. : . * * :*: : .::***:***:***.*. *:*:* :.: : : : : :*:** *:. .. *::*.* * :: : ..: **:*:** **::*** ::*: ", "identical_positions": 225, "similar_positions": 196, "identity": "41.06%" }, { "cls_id": "homologset.agr.SGD:S000002597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62991-1", "uniprot_id": "SCFD1_RAT", "id": "Q62991-1", "name": "Sec1 family domain-containing protein 1", "aln": "---MVGSKMAA--SIRERQTVALKRMLNFNVPHVKN-----------SPGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIRDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDP--LGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPTGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMA---STPASYGNTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG----KHILYGCSEIFNATQFIKQLSQLGQK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRF7-1", "uniprot_id": "SCFD1_MOUSE", "id": "Q8BRF7-1", "name": "Sec1 family domain-containing protein 1", "aln": "---MVGSKMAATASIRERQTVALKRMLNFNVPHVKN-----------STGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDP--LGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMA---STPASYGNTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKAKQG----KHILYGCSEIFNATQFIKQLSQLGQK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVM8-1", "uniprot_id": "SCFD1_HUMAN", "id": "Q8WVM8-1", "name": "Sec1 family domain-containing protein 1", "aln": "MAAAAAATAAAAASIRERQTVALKRMLNFNVPHIKN-----------STGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDT--LGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEADLEQYKKALTDAGCNLNPLQYIKQWKAFTKMA---SAPASYGSTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRGNDSSVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG----KHILYGCSELFNATQFIKQLSQLGQK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PC92-1", "uniprot_id": "A0A8M1PC92_DANRE", "id": "A0A8M1PC92-1", "name": "Sec1 family domain-containing protein 1", "aln": "--------MAA--SIREKQTAALKRMLNFNAPPLKN-----------TTAEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAIYFIMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASAALAANAVNQVTKVFDQYLNFITLEDDMFILCNQNKEHISYHAINKPDIMDTDMEGIMDTIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDT--MGTGQFSFQRPLFVLADRNLDLATPLHHTWTYQALIHDVLDFHLNRVSVDESHGSEASPAGARPKKKNKKSYDLTAADKFWQKHKGSPFPEVAEAVQEELDTYRAQEDEVKRLKSIMGLEGEDDGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLMSKSTLDKSLLDIISDPDAGTAEDKMRLFLIYYITSQQPPLEADLEQYKKAMVDAGCDLSPLNYIKQWKAFTKMA---ATPANYGSSG-----------VKPMGLFSRVMNTGSQFVMEGVKNLVLKQHNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRGSESSIPRNKNPFQEAIVFVVGGGNYIEYQNLVDYTKTRQG----KRILYGCSELFNAAQFIKQLSQLGQK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24179-1", "uniprot_id": "SLY1_DROME", "id": "Q24179-1", "name": "Protein sly1 homolog", "aln": "-----------MLTLRERQINAIKQMLNLNSQQPKA-----------LAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVED----ETASAGAR---KKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP-ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGG-----------TKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAE-----TDDYLYLDPKLLKGGE-VLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALGGEIQSPTATS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22213-1", "uniprot_id": "SLY1_YEAST", "id": "P22213-1", "name": "Protein SLY1", "aln": "-MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDDIFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISN----AYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQ-----GNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIPLES-KENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLD----PNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSR-FLDILKDGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPK-RQSYNKSLVFVVGGGNYLEYQNLQEWAHSQLHN--PKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: * *: :** :* : * :**:** * . **.:: :::* . *:*:* ::.**..: ****:** **.**:* : :*: . *. :::** :.:.*. :*::* . :. :: :*:***::** * ::* * .: :* ::* .. : :: : .*.*.** .:*:. :****..:. .**::* ** .***: : ::. . * *::* :::: ***:*:*: : *:* **.::.*::.: * * : * .. .: * *: * ** :. *** .** :: *::*: . *:.* . .:.. . . .: *.:: ..*..**:* **. ** * :: :*:*. :::: ** :** *:. *. * .: :**:: * . . ***:* ::: :: : : :. :: : . ::..* *: : : : : : . . .: :. * ::.*:*:*: :::.:*:*.: : :*: ...: **.* *:***: :... *: : .::.::**:******:***** :: : : ::::**.: : .. :*::::* ** . ", "identical_positions": 158, "similar_positions": 249, "identity": "23.03%" }, { "cls_id": "homologset.agr.SGD:S000002598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60122-1", "uniprot_id": "RUVB1_MOUSE", "id": "P60122-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60123-1", "uniprot_id": "RUVB1_RAT", "id": "P60123-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y265-1", "uniprot_id": "RUVB1_HUMAN", "id": "Q9Y265-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K0H9-1", "uniprot_id": "A0A0G2K0H9_RAT", "id": "A0A0G2K0H9-1", "name": "RuvB-like helicase", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLIGQENAREACGVIVELIKSKKMAGRAVLLAGPPETGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEKYVPLPNGDVHKKKEIIQDVTLQYLDVANVRPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDE-----------------SSITPIVIFASNGANCVIRGTENITSPHGIPLDLLDRVIIIRTMLYTPQEMKQIIKIRAQGMEGINISEEALNHLGEIGTKTMLRFSVQLLTPANLLAKINRKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8AWW7-1", "uniprot_id": "RUVB1_DANRE", "id": "Q8AWW7-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDEAGNAKQSASGLVGQESAREACGIITELIRSKKMAGRAILLAGPPGTGKTALALAMAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIYESLQKERVEVGDVIYIEANSGAVKRQGRCDTFATEFDLEAEEYVPLPKGDVHEKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFIDEVHMLDIECFTYLHRALESSIAPIVVFASNRGNCLIRGTEDISSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGLNISEEALSHLGEIGTKTTLRYAVQLLTPASLLARVQGREVVEKEHVEEINELFYDAKSSAKILQDQHTKFMK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH07-1", "uniprot_id": "RUVB1_DROME", "id": "Q9VH07-1", "name": "RuvB-like helicase 1", "aln": "-MKIEEVKS--------TVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRALLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSMMGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIAPIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQ-TEGLQLEENAFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKFML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03940-1", "uniprot_id": "RUVB1_YEAST", "id": "Q03940-1", "name": "RuvB-like protein 1", "aln": "MVAISEVKENPGVNSSNSGAVTRTAAHTHIKGLGLDESGVAKRVEGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPSTGKTALALAISQELGPKVPFCPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYGKTISHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAYATEFDLETEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVISMMGQLLKPKKTEITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIFTYLNKALESNIAPVVVLASNRGMTTVRGTEDVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRAT-VERLQVESSALDLLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAKRSTKILETSAN-YL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.***. : . * *:*:*:******* * * : .*::** ****.*::.:**::***:***:**** * *****:***::**** ******:****::* *:****.*******:*****:*************** ::***:********:*::***:***** *:***:*::::*:*:*. *********:***** **.*::*******:*:*****:*:**:***::*****: *****.*******::******:********:*** *:**** ******:***:*****:** * *:*:*::*:* . :*** :: ****:* **:**::*:**: * ::. **: ** * :::...*: *. :**.: **:::***:*. :.: . :. : :.::: ** *** *:* * . :: ", "identical_positions": 257, "similar_positions": 119, "identity": "55.15%" }, { "cls_id": "homologset.agr.SGD:S000002604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY55-1", "uniprot_id": "DCAKD_RAT", "id": "Q6AY55-1", "name": "Dephospho-CoA kinase domain-containing protein", "aln": "MFLVGLTGGIASGKSSVIQVFQ-QLGCAVIDVDVIARHIVQPGCPAHRRIVEAFGTEV---LLENGDINRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRN-NLNREDAEARINSQLPLKDKARMANHVLDNSGEWSLTRRQVILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSPQLGNPGSKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHC4-1", "uniprot_id": "DCAKD_MOUSE", "id": "Q8BHC4-1", "name": "Dephospho-CoA kinase domain-containing protein", "aln": "MFLVGLTGGIASGKSSVIQVFQ-QLGCAVIDVDVIARHVVQPGYPAHRRIVEAFGTEV---LLENGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRN-NLNREDAEARINAQLPLKDKARMANHVLDNSGEWSLTRRQAILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVC6-1", "uniprot_id": "DCAKD_HUMAN", "id": "Q8WVC6-1", "name": "Dephospho-CoA kinase domain-containing protein", "aln": "MFLVGLTGGIASGKSSVIQVFQ-QLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEV---LLENGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRN-SLNRKDAEARINAQLPLTDKARMARHVLDNSGEWSVTKRQVILLHTELERSLEYLPLRFGVLTGLAAIASLLYLLTHYLLPYA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P4C4-1", "uniprot_id": "DCAKD_DANRE", "id": "Q0P4C4-1", "name": "Dephospho-CoA kinase domain-containing protein", "aln": "MFLVGLTGGIASGKSTVSSQLK-ELGCPVIDADVVARKVVEPQTAAYRLIVRHFGQEV---LSENGEIDRKKLGQIIFSSPEKRRLLNSITHPEIHKEMLKQILLYFIKGYRYVILNVPLLFETRRLTRFLTHTVVVYCDPATQLSRLMQRD-ALSQTEAEQRISAQMPLKEKRGLANHVIENSGSREDTHRQVLRLHSKLDDCMQFLIIRAVAVAALTGLGG-LFIYTVKIITS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI57-1", "uniprot_id": "Q9VI57_DROME", "id": "Q9VI57-1", "name": "Dephospho-CoA kinase domain-containing protein", "aln": "MFIVAVTGGIATGKSTISKVFE-RQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEV---LLPSKEINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPLLFETGVLMDFIHKIVCVTCDSDKQLERLIARN-ELSESEARHRVDSQMPLDKKCEKSHFVIDNNGSVEEAESSAMSIYNLMRDSKQHWLNRISFLGLFLIVGFTIYMLLKVFNRLPESWQM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03941-1", "uniprot_id": "CAB5_YEAST", "id": "Q03941-1", "name": "Dephospho-CoA kinase CAB5", "aln": "MLVVGLTGGIACGKSTVSRRLRDKYKLPIVDADKIARQVVEPGQNAYDQIVLYFKDKIPNLLLEDGHLNREALGKWVFSHKEDLQALNGITHPAIRYAMFKEIGYYYLKGYRMCVLDVPLLFEG-NLDSICGVTVSVICTQELQLERLMTRNPELSEEDAKNRLNSQMSTEERMARSDYILQNNSTLVDLYEQIESVVKKIQPSK--LRTVLEYFPPFGAVSASSIVMSRLLMKKLQNKKSSAV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*.:***** ***:: :. . .::*.* :**.:*:* . * * :: * . .::* **. :*. : ** **** *: :: : : *: :*::***** * * * * ** **: *: *.. :*. *:.:*:. .: : .:::*.. . : : . . : :. : : ", "identical_positions": 51, "similar_positions": 67, "identity": "20.82%" }, { "cls_id": "homologset.agr.SGD:S000002606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58467-1", "uniprot_id": "SETD4_MOUSE", "id": "P58467-1", "name": "SET domain-containing protein 4", "aln": "MQRRRGRTERARKRRRR-SSGSRAVNESYRSEFIELRKWLKERKFE-DTDLVPASFPGTGRGLMS-KASLQEGQVMISLP-----------ESCLLTTDTV-----IRSSLGPYIKKWKPPVSPLLALCTFLVSEKHAG-------CRSLWKSYLDILP-----KSYTCPVCLEP-----EVVDLLPSPLKAKAEEQRARVQDLFTSARGFFSTLQPLFAEPVDSVFS--------YRAFLWAWCTVNTRAVYLRSRRQ-------ECLSAEPDTCALAPFLDLLNHSPHVQVKAAFNEKTRC------------YEIR--TASRCRKHQEVFICYGPHDNQRLLLEYGFVSVRNPHACVPVSADMLVKFLP-----AADKQLHRKITILKDHGFTGNLTFGWD-GPSWRLLTALKLLCLEAERFT-SWKKVLLGEVISDTNEKTSLGVAQKICSDVIEETHAVLRKVSDMKEGTVSLRSQLSLVEALRMEELRILQASAEILSGLLAPFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVD3-1", "uniprot_id": "SETD4_HUMAN", "id": "Q9NVD3-1", "name": "SET domain-containing protein 4", "aln": "MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQ-DSNLAPACFPGTGRGLMS-QTSLQEGQMIISLP-----------ESCLLTTDTV-----IRSYLGAYITKWKPPPSPLLALCTFLVSEKHAG-------HRSLWKPYLEILP-----KAYTCPVCLEP-----EVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSLQPLFAEAVDSIFS--------YSALLWAWCTVNTRAVYLRPRQR-------ECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHS------------YEIR--TTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLP-----STDKQMDKKISILKDHGYIENLTFGWD-GPSWRLLTALKLLCLEAEKFT-CWKKVLLGEVISDTNEKTSLDIAQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRASAETLHSLQTAFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVB0-1", "uniprot_id": "Q7KVB0_DROME", "id": "Q7KVB0-1", "name": "SET domain-containing protein 4", "aln": "----MGRTQRRRHQRAKKSDENSGS-------LHDLYVHLHSVGWQNHTHLSAQYYEQTGRGLCSKQKTFSPEDELIRLP-----------IGCLISIATLESDGPFKSLFDEELFDKDSRISFQALIACYILYHKHLQECTLG-THSSTYAAYLDTLP-----RCYSTPYFCSI-----PELQCLPESLLERTVAQNRQIRGYFEIIKNIVHKCDCCGKSYGQEIWT--------LADFKWAYFSVNTRSVHLSSRFLKKQSNYFQPLISGDTNLALAPFLDLFNHSDQVEITAGIEGPDYV------------LTLKSLPFSETKPYDQLFISYGALPNFKLLTEYGFWLRENKHDYFEVSLLDIEHMIKQNKELSTQTFHRNIFKFIREHNLNDQMFVHIDDGCSHNLRVVLHLIFKQQAYFPNILNQIAFGDAEQFQDVQPELSYLVEYKIKEYEIFGGELDKLPKLTESGAVARSYLQECIRYLVDFQSVHLAA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03942-1", "uniprot_id": "RKM2_YEAST", "id": "Q03942-1", "name": "Ribosomal lysine N-methyltransferase 2", "aln": "---MEGKVDVLLTWLKKSDKFYIAPNISICESPETGRGIVLSHGSIRKNDIIVSVPSSKQLNFHTILYHISKFNKELNIPGITIDRKPINYEDNIIEAENKAWADPRYGLYSELSKEFLLSLSSFQLVSFYILVENFLLPKWTHNEIYSDWKPFFDVWPSMEELRSIPAIWNCDPNSRYHSLIEYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGSLSCTKNSDKFTSDELFSLFVHVYFIINSRCLYAKIPLK---------IEDSPSNFTLVPYVDFMNHICESDLHCYPQLSPQLRSEGENIIGIGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLNEYGFVVDGNKWNYLDISDEIIELIDD---------DKKEVKTFLLEHDYWGDYTINET-DISYRIFVALNYYVTRDERRVRKFIEGYISEDYFKPKISSVLKELLVSLTAKYTKTLSELTEKVSNLENNLCLQNLITIYKGYIKILTQHLQDLQS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.. .. . : ...: . .: : :. : : :* . :: . . . . * :. ::: .:. * : .::: * :. . . :: ** . : :: : .. . : . : : .: :*:*.:: : . :*.*::*::** . :: . : :: . :::*: **. * *: **** * . :* : . .:: :*. : . . * .: ..*: . : :.: . .. * . * : : . : ", "identical_positions": 30, "similar_positions": 117, "identity": "5.87%" }, { "cls_id": "homologset.agr.SGD:S000002608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3URD3-1", "uniprot_id": "SLMAP_MOUSE", "id": "Q3URD3-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK-VTHGCIVSTIKLFLPDGMEARLRS-DVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVR-LEHLQEKTLKECSSLG-IQVDDFLPKINGSTEK-EHLLSKSGGDCTFIHQFLECQKK-LMVQGHLTKVVEESKLSKE-NQAKAKESDLSDTLSPSKEKSSDDTT-DAQMDEQDLNEPLAKVSLLKDD-LQGTQSETEAKQDIQHLRKELVEAQELARTSKQKCFELQ-ALLEEERKAYRNQVEESAKQIQVLQ-VQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQG-ELEKLKKEWDVLETECHSLKKENVLLSSELQRQEKELHN-SQKQSFELTSDLSILQMTRKELEKQVGSLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWPWMPMLAALVAVTAMVLYVPGLARASP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C219-1", "uniprot_id": "SLMAP_RAT", "id": "P0C219-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVVTHGCIVSTIKLFLPDGMEARLRSDDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELVALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLREMNERTQEELRELANKYNGAVNEIKDLSDKLKAAEGKQEEIQQKGQAEKKELQAKIDDMEEKEQELQAKIEALQADNDFTNERLTALQVVRLEPLQEKTLKECSSLGGIQVDDFLPKINGSTEKEERLLSKSGGDCTFIHQFIECQKKKLMVQGHLTKVVEESKLSKEENQAKAKESDLSDTLSPSKEKSSDDTTDDAQMDEQDLNEPLAKVSLLKDDDLQGTQAETEAKQDTQHLRKELVEAQELARASKQKCFDLQAALLEEERKAYRNQVEESAKQIQVLQVVQLQRLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLHQAAAKAVSERDTDFMSLQEELKKVRAELEGWRKAASEYEEEIRSLQSTFQLRCQQCEVQQREEATRLQGGELEKLKKEWDVLENECRSLKKENVLLSSELQRQEKELHNNSQKQSLELTSDLSILQMTRKELENQMGSLKEQHLRDEADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWPWMPMVAALVAVTAMVLYVPGLARASP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BN4-1", "uniprot_id": "SLMAP_HUMAN", "id": "Q14BN4-1", "name": "Sarcolemmal membrane-associated protein", "aln": "MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK-VTHGCIVSTIKLFLPDGMEARLRS-DVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVR-LEHLQEKTLKECSSLE-------------------HLLSKSGGDCTFIHQFIECQKK-LIVEGHLTKAVEETKLSKE-NQTRAKESDFSDTLSPSKEKSSDDTT-DAQMDEQDLNEPLAKVSLLKDD-LQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQ-ALLEEERKAYRNQVEESTKQIQVLQ-AQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQG-ELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHN-SQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03944-1", "uniprot_id": "VPS64_YEAST", "id": "Q03944-1", "name": "Vacuolar protein sorting-associated protein 64", "aln": "-----------------------------MVELEKRRRPPPQ-----------------LQHSP---YVRDQS-------NSQGMTKTPETSPP------------------------------------------------------KRPMGRARSNSRSSGSRSNVDIDQY----------------TIPPGLDLLPTASSPPSVHQVSQQQQLS--PILANKIRSPFENQSQD---------QNDNSIDPTPAGQVTIPVEAVSPPALDELSKFQNGSTETLFRTGSPRKK-HTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFS----------------QQVRPDNGNFDS--------------------------------------------RVLSRN-------HACLSCDPT----SGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLG---TDIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQ-DHTNKNNGNSTNINGIKIDRGHHNQ-------HIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSGIFINNSAGTSIN-LINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDMNEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHE----KLQELESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLISTEELGVVEGKRTR-----------------------VSKGMLFGVVAISFGLVATAVKQLPQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * **. : ::*.. *::* . *** ::: .* *** *:.:. :*: * *:. .::.** *: * : **... :.::: ** ::.*:::: :**::* *:*: *.* : * . .: :**:.:.. ::* . :: . *:.* .:: . : .* ** .. :.::::....*::* : ::.**. :. ::**:. * :.*: . .*:: ::. .. * .: ::.*.. .:. : : . * *::::.:.:. : ::*:: . :: *:: :* .*: :: :: . :: .. * : . *.:::*. .: * . . *: :: : : :::*: . : . :::.::*. . . : :* **. : *** :. . :: .*: : : * : : :* ** *: . * : :.:*::* :.* . :**: *: : ** *:* *:: :* . : *.:.::.. : .. . :*:::: :*: *.* .** : : .* : : :: *:: * :* ", "identical_positions": 102, "similar_positions": 254, "identity": "11.89%" }, { "cls_id": "homologset.agr.SGD:S000002610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7D2-1", "uniprot_id": "ROGDI_RAT", "id": "Q4V7D2-1", "name": "Protein rogdi homolog", "aln": "-----MATAMAASAAERAVLEEEFRWLLHAEVHAVLRQLQDILKEASLRFTLPGPSTEGPAKQENFILGSCG----TDQVKGVLTLQGDALSQADVNLKMPRNNQLLHFAFREDK--QWKLQQIQDARNHVSQAIYLLA----NRDESYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPTLPSDLLVNVYINLNKLCLTVYQLHTLQPT--------------------STKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIP-----------WLNDALVYFTVSLQLCQQLKDKISVFSSYWSSRPF------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TDK6-1", "uniprot_id": "ROGDI_MOUSE", "id": "Q3TDK6-1", "name": "Protein rogdi homolog", "aln": "-----MATAMAASAAERAVLEEEFRWLLHAEVHAVLRQLQDILKEASLRFTLPGPSTEGPAKQENFILGSCG----TDQVKGTLTLQGDALSQADVNLKMPRNNQLLHLAFREDK--QWKLQQIQDARNHVSQAIYLLA----NRDESYQFKTGAEVLKLMDAVMLQLTRARSRLTTPATLTLPEIAASGLTRMFAPTLPSDLLVNVYINLNKLCLTVYQLHALQPT--------------------STKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIP-----------WLNDALVYFTVSLQLCQQLKDKIAVFSSYWSSRPF------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZN7-1", "uniprot_id": "ROGDI_HUMAN", "id": "Q9GZN7-1", "name": "Protein rogdi homolog", "aln": "-----MATVMAATAAERAVLEEEFRWLLHDEVHAVLKQLQDILKEASLRFTLPGSGTEGPAKQENFILGSCG----TDQVKGVLTLQGDALSQADVNLKMPRNNQLLHFAFREDK--QWKLQQIQDARNHVSQAIYLLT----SRDQSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVYINLNKLCLTVYQLHALQPN--------------------STKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIP-----------WLNDALVYFTVSLQLCQQLKDKISVFSSYWSYRPF------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVT5-1", "uniprot_id": "ROGDI_DANRE", "id": "Q7ZVT5-1", "name": "Protein rogdi homolog", "aln": "--------MTAASQAERTVLEEEFNWLLKEEVHAVLKQLQDILKEASRRLSMPSPGLEGQLKQENFILGSST----MDQVKGVLTLQGEALTQADINIKVAKSSQVMHFAFRDDK--QWKLQQIQDARNHVNQALQLLS----SRDDSYHFKTGAEVNKLMDAIMLQLTRARNRLTTPASMTLPELAASGLMKMFTPPMPGDVMVNFYINLSKLCLTVYQLHVLQPN--------------------TTKNFKPAGSSVLHNPGAMFEHNNTKFEVSHVHKVECVVP-----------WLNDTLVFFTISLQLCQQLKDKISVFSSFWNYRPF------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03956-1", "uniprot_id": "RAV2_YEAST", "id": "Q03956-1", "name": "Regulator of V-ATPase in vacuolar membrane protein 2", "aln": "MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIIDNFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQFQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMELLNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIELRNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHIISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASMANHQANLVASKQLSTYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ::: .. . * ** :*:.: * : : .. .* * ... ***.:* **: : : .: ::..: .: :. ** :. :: * *:.. .*:.: : :* * * ... . . :*:: :: * .. *. * .:. . . . : ::. : .:**: : :* : . *:: . : . :* . *. .: .. .: .: *.: ::: :* .* :. . *:: :. . :. ", "identical_positions": 35, "similar_positions": 114, "identity": "9.97%" }, { "cls_id": "homologset.agr.SGD:S000002612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZU1-1", "uniprot_id": "COQ4_RAT", "id": "Q4FZU1-1", "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "aln": "-------------------MAT-LLLRSQ-RLHRSLRHRTRPTVDVLLRAASHGARLLYPDH-------------------------IPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKF-LRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLNANKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPVRLRAQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPK----HIQGLA-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGB8-1", "uniprot_id": "COQ4_MOUSE", "id": "Q8BGB8-1", "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "aln": "-------------------MATLLLLRSL-RLHRSLRPRTRPAVDVPLRAGSHGARLLYPDH-------------------------IPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKF-LRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLDVNKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPIRLRTQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPK----HIQGLA-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3A0-1", "uniprot_id": "COQ4_HUMAN", "id": "Q9Y3A0-1", "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "aln": "-------------------MAT-LLRPVL-RRLCGLPGLQRPAAEMPLRARSDGAGPLYSHH-------------------------LPTSPLQKGLLAAGSAAMALYNPYRHDMVAVLGETTGHRTLKV-LRDQMRRDPEGAQILQERPRISTSTLDLGKLQSLPEGSLGREYLRFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNILGEIVVKWFEAVQTGLPMCILGAFFGPIRLGAQSLQVLVSELIPWAVQNGRRAPCVLNLYYERRWEQSLRALREELGITAPPM----HVQGLA-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9JR86-1", "uniprot_id": "COQ4_DANRE", "id": "A9JR86-1", "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "aln": "-------------------MRG-LPGAFLGSFKTSYGYLSQRLYGVLTEEKYDGR--LYPSH-------------------------IPTSTVQKAILAVGSGVAALKNPYRHDMVAVLGETTGHQTLIK-LRDRMRNDPEGSTILLERPRIRLSTLDLSNMSALPDGTLGREYLRFLEENRVTPDTRAEVKFVDNEELAYVMQRYREVHDLLHTLLGMPTNMLGEVAVKWFEAAQTGLPMCILGAALGPLRLSVSRLQLLGQSLGLWALRNGGRARCVLSIYYERRWEQTLDELRHELNIEEPPVSLIASIKNSSSKS----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVG6-1", "uniprot_id": "COQ4_DROME", "id": "Q9VVG6-1", "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "aln": "------------------MMQRCLRLQKPLALRRGLRLAQANSQAVATEAPEAEPLDAFERQYLK--------------------ERIEISPFQRLFLGAGSSIAALLNPRRHDMIACLGETTGEDALWT-ILDTMQASEEGQRIMADKPRIHTSTIDFKYLETLPPDTFGAAYVKFLKDNQVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLDMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLRPKQRRAYLKHYLPWALENGKRTKPLMPVYWEKRWEQNIHELRSELGIT---------VLNKA-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O13525-1", "uniprot_id": "COQ4_YEAST", "id": "O13525-1", "name": "Ubiquinone biosynthesis protein COQ4, mitochondrial", "aln": "MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLADAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAISGWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMDKLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITNMPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSCKPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTPA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : :: :* . :. :: :* :. ***:*. .: : : * . .* *: ::*.* . :.: : ** .::* * ::*. :.*:**:* .:*::: **:: ***: **: *:: .** : **:.:* .*. : *:**. *. :..:** : . **:..* :: :*:*. *: : ** ** * : ", "identical_positions": 53, "similar_positions": 81, "identity": "15.82%" }, { "cls_id": "homologset.agr.SGD:S000002613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJM8-1", "uniprot_id": "ZNT7_RAT", "id": "Q5BJM8-1", "name": "Zinc transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPLS--------IKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHE-RLLLVSILGFVVNLVGIFVFNHGGHGHSHG-SGHGHSHSLFNGALDHSHGHEDHCHSHGAK---HGGAHSHDHDHAHG-HGH----LHSHDGPSFKETAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESIGILMQRTPPSLENVLPQCYQRVQQLQGVYNLQEQHFWT-----------------------LCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKN1-1", "uniprot_id": "ZNT7_MOUSE", "id": "Q9JKN1-1", "name": "Zinc transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPLS--------IKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHE-RLLLVSILGFVVNLVGIFVFNHGGHGHSHG-SGHGHSHSLFNGALDHSHGHEDHCHSHEAK---HGAAHSHDHDHAHG-HGH----LHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGVYNLQEQHFWT-----------------------LCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEW0-1", "uniprot_id": "ZNT7_HUMAN", "id": "Q8NEW0-1", "name": "Zinc transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPLS--------IKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHE-RLLLVSILGFVVNLIGIFVFKHGGHGHSHG-SGHGHSHSLFNGALDQAHGHVDHCHSHEVK---HGAAHS--HDHAHG-HGH----FHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWT-----------------------LCSDVYVGTLKLIVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMX1-1", "uniprot_id": "ZNT7_DANRE", "id": "A5PMX1-1", "name": "Zinc transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPLS--------IKDDEYKPAKFNLVVKLSGWFRSILADKTSRNLFFFLCLNLSFAFVELLYGIWSNSLGLISDSFHMFFDCTALLAGLAASVISRWRSNDSFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALEPPDVHHD-RLLPVSIAGLLVNLVGIFVFQHGGHGHSHGGDDHGHSHSLFNGSAAHGHSHGGHGHSHGGHGHSHESKHGHDHGHSHGGHGHSHDDQHCHDDHTLTPGKGSSKQILQGVFLHIVADTLGSVGVIISAILMQKYDLMIADPICSMLIALLIGVSVVPLLRESIGILMQRTPPSLDHALPECYQRVQQLQGVYNLQEPHFWT-----------------------LCTDVYIGTLKLLVAPDADSRWILSQTHNIFTQVGVRQLYVQIEVAAM----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGS1-1", "uniprot_id": "Q9VGS1_DROME", "id": "Q9VGS1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPLS--------HKDR--SSLGYRIREKLNSWKRLIFSDRNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLISDSFHMFFDCTGLLAGLAASVITKWKANDKFSYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERLIEPPEVKHE-RLFVVSVLGLLVNLVGIYAFNHGGHGHSHG--GHGHSH-----GGGHGHGHS-HGHTDAGN----HNHQAITLDNGHG-HSH----DHDSHGHSHGDMSGSNSQIMRGVFLHILADTLGSVGVIISAVLMHMFGWMIADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTGLAGVYAVQEPHFWT-----------------------LCSDVYVGALKLEVSKNVDPKYVVTHTRMIFEAVGVKQIYIQLDYV------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R4H9-1", "uniprot_id": "ZNT5_MOUSE", "id": "Q8R4H9-1", "name": "Proton-coupled zinc antiporter SLC30A5", "aln": "MEEKYGGDARPGPGGG--LGPVDVPSARLTRYILLLCLTKCLKAVG---LFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKPITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSIDVGGAKRLQALSQLVSVFLLCPWVIVLSVTTESKVESWFSLIMPFTTVIFFVMILDFYMDSVCSVKMDVSKCARYGSFPIFISALLFGNFWTHPITDQLRAMNRAAHQESTEHVLSGGVVVSAVFFILSANILSSPSKRGQKGTLIGYSPEGTPLYHFMGDAFQHSSQSVPRFIKDSLKQVLEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTN-MLTPVSVGGLIVNLIGICAFSH---AHSHG---HGASQG---NCHS-DHGHSHHAHGHG-----------------------------HDHGHSHGFTGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAVLIFLSVIPLIKDACQVLLLRLPPDHEKELHIALEKIQKIEGLISYRDPHFWR-----------------------HSASIVAGTIHIQVTSEVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESLKYCKDGTYIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZY54-1", "uniprot_id": "D3ZY54_RAT", "id": "D3ZY54-1", "name": "Zinc transporter", "aln": "MEEKYGGDPRPGPGGG--LGPVDVPSARLTKYIVLLCLTKCLKAVG---LFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTVTKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSIDVGGAKRLQALSQLVSVFLLCPWVIVLSVTTESKIESWFPLIMPFTTVIFFVMILDFYMDSVCSVKMEASKCARYGSFPIFISALLFGNFWTHPITDQLRAMNRAAHQESTEHVLSGGVVVSAVFFILSANILSSPSKRGQKGTLIGYSPEGTPLYHFMGDAFQHSSQSVPRFIKDSLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALVSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFLESVARLIDPPELDTN-MLTPVSIGGLIVNLIGVCAFSH---AHSHG---HGPSQG---HCHS-DHGHSHHAHGH------------------------------SDHGHSHGFTGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAVLIFLSVIPLIKDACQVLLLRLPPDYEKELHIALEKVQKLEGLISYRDPHFWR-----------------------HSASIVAGTIHIQVTSDVLEQRVVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTQQMESMKYCKDGTYIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAD4-1", "uniprot_id": "ZNT5_HUMAN", "id": "Q8TAD4-1", "name": "Proton-coupled zinc antiporter SLC30A5", "aln": "MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVG---LFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQALSHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSKCARYGSFPIFISALLFGNFWTHPITDQLRAMNKAAHQESTEHVLSGGVVVSAIFFILSANILSSPSKRGQKGTLIGYSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTH-MLTPVSVGGLIVNLIGICAFSH---AHSHA---HGASQG---SCHSSDHSHSHHMHGHS----------------------------DHGHGHSHGSAGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWR-----------------------HSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG36-1", "uniprot_id": "ZNT5_DANRE", "id": "Q6DG36-1", "name": "Proton-coupled zinc antiporter SLC30A5", "aln": "MDEKYSSNVISSGK----LGRVEAPNARLTRYIVLLYFTKMLKAFG---IFESYDILKVVHIVQFLFILKMGCAVILVFFQKPFSSGKMIPKRQWIKILKHAVISCIISLLGFFGLTLCGPLRSLLLFEHSDLVVISLLSVLFTSSGGGPSKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHALYTGIAFLGVADHKGGVVLLVLALCLKVAFNTASRKLSVEIGGAKRLYALSNLVSAVVLLPWVIVLSATTESKVESWSGLIFPFAMIIFSVMILDFYVESICMAKLETSRCARYGAIFLFLNGLLLANFWTHPLTGQIRAISTTGQQSSTEHVLSGGVLVSACFFIMADSILSAPSSKGQKGTLVGYSPEGTPLYNFMGDALQHTSQSLPRFIKDSLKQILEEYDSRQIFYFLCLNLAFTFVELFYGVWTNSLGLISDGFHMLFDCSALVLGLFAALMTRWKATRIYSYGYGRVEILSGFINGLFLMVIAFFVFVESVTRLVDPPNINTD-MLTPVSVGGLIVNLVGICAFSH---AHS-----HGASKG---SCSGHDHGHSHHGHGHSSM------------EHSHGGHGHSHGGHGHSHGHGHSHSSGGMNANMRGVFLHVLADTLGSVGVIISTILIRQFGWLIADPICSLFISTLIFLSVIPLLKDACEVLLLRMPPQHEKELNFALEKIQKIEGVLSYRDPHFWR-----------------------HSASVIAGTIHLQLMSDVVEQRVIQQVSAVLKDAGVNNLTIQLEKEAYFQHMSGLSSGFHEVLTMTQQMESMKYYKDGTCIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03455-1", "uniprot_id": "MSC2_YEAST", "id": "Q03455-1", "name": "Probable zinc transporter MSC2", "aln": "----------------MNLQELLAKVPLLLSYPTIILSSNLIVPSHNDLISRAASTSAAEYADEKLIFFSTDHAIRLIFLPTFVASSFNLFAHYFNFINYSSRRKYYVLFTAIYFLSILT-----AIFHPIQSTCITLLIIKLLTTADESSPKIALNFKTILKTFVPFITLTLVILRWDPSFDASSGDVNKISTSLAAYALLILTLRYASPLILSTLSSSIGVVSKDTSVAQHSISRNKRFPLILVLPIFSFVLLYLMTIVNKTYNIQLLMVFVFFGCLSIFFLSLKDLFTEDGNQKKGGQEDEYCR----MFDIKYMISYLWLTRFTILLTGIMAIVVHFLSFNEITSSIKTDLLSLLFVVVAEYVSSFSNKQPDSHSHN---------HAHHHSHLTDSLPLENESMFKQMALNKDTRSIFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGLNYLGTLAGFTNGVLLLGIVCGIFVEAIERIFNPIHLHATNELLVVATLGLLVNLVGLFAFDHG----------------------AHDHG-------------------------------------------------GTDNENMKGIFLHILADTLGSVGVVISTLLIKLTHWPIFDPIASLLIGSLILLSALPLLKSTSANILLRLDDKKHNLVKSALNQISTTPGITGYTTPRFWPTESGSSGHSHAHTHSHAENHSHEHHHDQKNGSQEHPSLVGYIHVQYVDGENSTIIKKRVEKIFENVSIKAWVQVEPQNSTCWCRATSMNTISANPNSLPLQPIAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : : :*.:* ** ** * **:*:*.. ::.***:**.:** :*.:.:: ** *.:::: . :.:* *:** *.::*: . :: *.: * . * .:. * *: *::***:*: .*.* *. * ::*:***::******:**: *::::. * **:.*::*. ** :*.:.*::.: :: * .. : . ::: *: :** . *: . : : *.:: ::. ", "identical_positions": 70, "similar_positions": 104, "identity": "8.44%" }, { "cls_id": "homologset.agr.SGD:S000002616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A3N6-1", "uniprot_id": "PIPSL_HUMAN", "id": "A2A3N6-1", "name": "Putative PIP5K1A and PSMD4-like protein", "aln": "-------------------------------------------------------------------------------------------------MA-------------SEV------------PYASGMPIKKIGHRSVDSSG-----GTTSSALKGAIQLGITHTVGSLSTKPESDVLMQDFHMVESIFFPSEGSNLTPAHHYNAFRFKTYAPVAFRYFWELFGIRPDD----YLYSLCSEPLIELCSSGASGSLFYVS---SDDEFIVKTVRHKEAEFLQKLLPGYYINLNQNP-RTLLP--KFYGLYCVQTG-GKNIRIVVMNN-----------LLPRSVKMHIKYDLKGSTYRRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADVHNALCKT----------LQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPL--------------------------------------------------SSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETD--DHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALIHDG-DTVSVHRPG------FYAEWFQRFMCNTVFKKIP-LKPSPSK---------------------KLRSGSSFSQRAGSSGN--SCITYQPLVSG--EHKAQVT-TKAEV----------EPGVHLGCPDVLPQTPPLEEISEGSPTPDPSFSPLVEETLQMLTTSVDNSEYMGNGDFLP--------------TRLQAQQDAVNT---------------------------------------VCHSKTRSNPENNVGLITLDNDCEVLTTLTPDTGRILSKLHTVQPKGKITFCMGIHVAHLALKHRQGNNHKIRIIAFVGNPVEDNEKNLVKLAKCLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISFPILAGEGGAMMGLGASDFEFGVDPSADPELALVLRVFMEEQRQRQEEEARQAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGHTGLPDLSSMTEEEKIVCAMQMSLQGAEFGLAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAVGSLASQATKDSKKDKKEEDKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99755-1", "uniprot_id": "PI51A_HUMAN", "id": "Q99755-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "aln": "-----------------------------------------------MASASSGPSSSVGFSSFDPA-------------VPSCTL-SSAASGIKRPMA-------------SEVLEARQDSYISLVPYASGMPIKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCSEPLIELCSSGASGSLFYVS---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQAG-GKNIRIVVMNN-----------LLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKT----------LQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPL--------------------------------------------------SSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETD--DHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDG-DTVSVHRPG------FYAERFQRFMCNTVFKKIP-LKPSPSK---------------------KFRSGSSFSRRAGSSGN--SCITYQPSVSG--EHKAQVT-TKAEV----------EPGVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTS----------------------------TTLEKLEVAESE---------------------------------------FTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70182-1", "uniprot_id": "PI51A_MOUSE", "id": "P70182-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "aln": "-----------------------------------------------MASASSGPAAAG-FSSLDAG-------------APAG---TAAASGIKRATV-------------SEG------------PSASVMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCSEPLIELSNSGASGSLFYVS---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQAG-GKNIRIVVMNN-----------LLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKT----------LQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPT--------------------------------------------------SNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETE--DHMGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDG-DTVSVHRPG------FYAERFQRFMCNTVFKKIP-LKPSPTK---------------------KFRSGPSFSRRSGPSGN--SCT-SQLMASG--EHRAQVT-TKAEV----------EPDVHLGRPDVLPQTPPLEEISEGSPVPGPSFSPVVGQPLQILNLS----------------------------STLEKLDVAESE---------------------------------------FTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSI8-1", "uniprot_id": "PI51A_RAT", "id": "D3ZSI8-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "aln": "-----------------------------------------------MASASSGPAAAG-FSPLDSG-------------VPAG---TAAS-GIKRGTV-------------SEG------------PYASLMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCSEPLIELSNSGASGSLFYVS---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQAG-GKNIRIVVMNN-----------LLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKT----------LQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPM--------------------------------------------------NSETQYSIDTRRPAPQKALYSTAMESIQGEARRGGTVETE--DHMGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDG-DTVSVHRPG------FYAERFQRFMCNTVFKKIP-LKPSPTK---------------------KFRSGPSFSRRSGPSGN--SCTPSQPTASG--EHKAQVT-TKAEV----------EPDIHLGRPDVLPQTPPLEEISEGSPVPGPSFSPAVGQPLQILNLS----------------------------STLEKLDVAESE---------------------------------------LTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PD30-1", "uniprot_id": "A0A8M9PD30_DANRE", "id": "A0A8M9PD30-1", "name": "", "aln": "-----------------------------------------------MASACPPDTGLSAPPDLRTP-------------FWSLLSSGRGSSGVRKMTI-------------TEG------------PGSSQSMKKTIGHRGVDPTGETTYKKTTSSALKGAIQLGIAHTVGSLSQKAERDVLMQDFYVVESIFFPSEGSNLTPAHHHGDFRFKTYAPIAFRYFRELFGIRPDD----YLYSLCNDPLIELSNPGASGSIFYVT---SDDEFIIKTVMHKEAEFLQKLLPGYFMNLNQNK-RTLLP--KFYGLYCVQAG-GKNIRIVVMNN-----------LLPRSVPMHLKYDLKGSTYKRRASPKERDKSVPTYKDLDFIQDMPEGIQLEPDNYNALCKT----------IQRDCLLLQSFKIMDYSLLVGVHNTDLASRERAGVVE--------------------------------------------GGGSEGTVTPDHRRPQIQKALYSTAMESIQGEAKGKGTLETE--DQWGGIPARNSRGERILVYIGIIDILQSYRFIKKLEHSWKALVHDG-DTVSVHRPG------FYAERFQRFMCNTVFKKT--LKSSPSK---------------------KSRSGCSSVVRRLPMGSTASAPGSQTLADARLVYRTHLNQSDLEG----------ESGMPSDRPDLLPQTDPLAGSSSEFAATNVSCSSPGSTRITSSSPPQRS-------------------------VGVEVHKSAVTE---------------------------------------PDNSTLHSTGAECLDEQLSNEDAISLKDIIPETDICF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70161-1", "uniprot_id": "PI51C_MOUSE", "id": "O70161-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "-----------------------------------------------MELEVPDEAESAEAGAVTAEAAWSAESG-------AAAGMTQKKAGLAEAPL-------------VTG-------------QPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNPGASGSVFYVT---SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQSG-GKNIRVVVMNN-----------VLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKT----------LQRDCLVLESFKIMDYSLLLGVHNIDQQERERQA--------------------------------------------------EGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETD--DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG-DTVSVHRPS------FYAERFFKFMSSTVFRKSSSLKSSPSK---------------------KGRG-ALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLE----------DEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEEP---HAEDLQKITVQVEP--------------VCGVG-VVPKEEGAGVEVPPCG------ASAAASVEID--AASQASEPASQASDEEDAPSTDIYF---------------------------PTDERSWVYSPLHYSAR--------------------------PASDGESDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I6B8-1", "uniprot_id": "PI51C_RAT", "id": "Q5I6B8-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "-----------------------------------------------MELEVPDEAESAEAGAVTAEAAWSAESG-------AAAGMTQKKAILAEAPL-------------VTG-------------QPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNPGASGSVFYVT---SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQSG-GKNIRVVVMNN-----------VLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKT----------LQRDCLVLESFKIMDYSLLLGVHNIDQQERERQA--------------------------------------------------EGAQSKADEKRPVAQKALYSTARESIQGGAARGEAIETD--DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG-DTVSVHRPS------FYAERFFKFMSSTVFRKSSSLKSSPSK---------------------KGRG-ALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLE----------DEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEEL---HAEDLQKITVQVEP--------------VCGVGVVVPKEQGAGVEVPPSG------ASAAATVEVD--AASQASEPASQASDEEDAPSTDIYFFAHGRYWLFSPRR-RRLRAVTPSHTGAPTDGRSWVYSPLHYSAR--------------------------PASDGESDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60331-1", "uniprot_id": "PI51C_HUMAN", "id": "O60331-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "-----------------------------------------------MELEVPDEAESAEAGAVPSEAAWAAESG-------AAAGLAQKKAAPTEVLS-------------MTA-------------QPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNPGASGSLFYVT---SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQSG-GKNIRVVVMNN-----------ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKT----------LQRDCLVLESFKIMDYSLLLGVHNIDQHERERQA--------------------------------------------------QGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESD--DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG-DTVSVHRPS------FYAERFFKFMSNTVFRKNSSLKSSPSK---------------------KGRGGALLAVKPLGPTAAFSASQIPSEREEAQYDLRGARSYPTLE----------DEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPSETSEQPRYRRRTQSSGQDGRPQEEPP--AEEDLQQITVQVEP--------------ACSVEIVVPKEEDAGVEASPAG------ASAAVEVETASQASDEEGAPASQASDEEDAPATDIYF---------------------------PTDERSWVYSPLHYSAQA------------------------PPASDGESDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5L6-1", "uniprot_id": "A0A8M3B5L6_DANRE", "id": "A0A8M3B5L6-1", "name": "", "aln": "-----------------------------------------------MEAAAAEGAASLSEAGDGSPLSGATASEDAGSADDVDADSISKKAFITEMPS-------------SSG-------------LPSHG--KKIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNPGASGSVFYLT---KDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFFGLYCVQSG-GKNIRMVVMNN-----------VLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKT----------LQRDCLVLESFKIMDYSLLLGVHNIDQAAKEQQM--------------------------------------------------EGSQGNSDEKRPLAQKALYTTAMESIQGASACGEGIDTD--DTMGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDG-DTVSVHRPS------FYADRFLRFMSSTVFRKTSSLKSSPSK---------------------RGRG-GLAVGKYCGPGAAWSASQLPFMRDENIYDLRGARSFPTLE----------DDGRADVLPCTPPSFEEATTASIATTLSSTTSLSIPERSPSDTSEHPRYRRHTQSSHEET--------MQDEDQQTITVEVEVEGRYD-------SEPTLVAPQVSPEISEAAETIPEASSSSVPASPRIVVESDGGSQASGCTSRASVDEEDDVPITDIYFFCDGSVHVCP--------PATHRRRHIPPEDKSWVYSPLHFSSGPKT----------------------LPEDEGESET----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G7V2-1", "uniprot_id": "A0AC58G7V2_DANRE", "id": "A0AC58G7V2-1", "name": "", "aln": "-----------------------------------------------MEAAAAGGCSALAEDADAVLGCGMEP---------AEIEAALKKTCLSEMPS-------------SSC-------------HSSSGPEKKIGHRRVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNPGASGSIFYVT---RDDEFILKTVMHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFFGLYCVQSG-GKNIRIVVMNN-----------VLPRVFRMHLKFDLKGSTYKRRASKKEREKNRPTYKDLDFMQDVQDGLLLDVDTYNALLKT----------LQRDCLVLESFKIMDYSLLLGVHNVEQAERERQM--------------------------------------------------EGSQG-SDEKRPAAQRALYSTAMESIQGGAACGDSIDTD--DTMGGIPAVSGKGERLLLFIGIIDILQSYRLIKKLEHTWKALVHDG-DTVSVHRPN------FYADRFFRFMSANVFKKSTSLKASPAK---------------------KGRS-VLAVPKFSVPGAAWSASQLPSERDENIYDLRGARSFPVLE----------NDG---LQSCTPPSFEEATTASVATTLSSNTSISIPERSPSDTSEHPRYRRHTLSLKDAEGRTHEVVDVHEEDQQTITVQVEVKRETEEDEDDRETDASQTHTDPETHIAAETEMVPPPPADSDPADDLETQTASSAPDDQENPPPADSEQQTAADPPEAESRSAESAEANPQTQLPPADPLSQSQSRESLEEELAANTDIYFVSRIMTGGCYFDFSCVSIRVVTIYRYDGLPRFERARLSYHEQLHINGFNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P70181-1", "uniprot_id": "PI51B_MOUSE", "id": "P70181-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 beta", "aln": "------------------------------------------------------------------------------------------------MSS-------------TAE-------------NGDAVPGKQNEEK--------TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDD----YLYSICSEPLIELSNPGASGSLFFLT---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCMQSG-GINIRIVVMNN-----------VLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKT----------LQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEE--------------------------------------------------EPLQNVPDAKRPGMQKVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDG-DTVSVHRPS------FYADRFLKFMNSRVFKKIQALKASPSK---------------------KRCN-SIAALKATSQEIVSSISQE--WKDEKRDLLTEGQSFSSLD---------EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVGEHYPHDRTTLYSNSKGLPSS------------------STFTLEEGTIY-------------------------------------------------------LTAEPNTLDLQDD-ASVLDVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5CZZ9-1", "uniprot_id": "PI51B_RAT", "id": "Q5CZZ9-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 beta", "aln": "------------------------------------------------------------------------------------------------MSS-------------TAE-------------NGDAVPGKQNEEK--------TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDD----YLYSICSEPLIELSNPGASGSLFFLT---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCMQSG-GINIRIVVMNN-----------VLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKT----------LQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEE--------------------------------------------------EPLQNAPDAKRPGMQKVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDG-DTVSVHRPS------FYADRFLKFMNSRVFKKIQALKASPSK---------------------KRCN-SIAALKATSQEILSSISQE--WKDEKQDLLTEGQSFSSLD---------EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVGEHYPHDRTTLYSNSKGLPSS------------------STFTLEEGTIY-------------------------------------------------------LTAEPNALETQDD-ASVLDVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14986-1", "uniprot_id": "PI51B_HUMAN", "id": "O14986-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 beta", "aln": "------------------------------------------------------------------------------------------------MSS-------------AAE-------------NGEAAPGKQNEEK--------TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDD----YLYSICSEPLIELSNPGASGSLFFVT---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCMQSG-GINIRIVVMNN-----------VLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKT----------LQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEE--------------------------------------------------ETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDG-DTVSVHRPS------FYADRFLKFMNSRVFKKIQALKASPSK---------------------KRCN-SIAALKATSQEIVSSISQE--WKDEKRDLLTEGQSFSSLD---------EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNSKGLPSS------------------STFTLEEGTIY-------------------------------------------------------LTAEPNTLEVQDDNASVLDVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUW9-1", "uniprot_id": "A0A8M3AUW9_DANRE", "id": "A0A8M3AUW9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MSS-------------ANA-------------NGVGSSGNNRREK--------TYKKTTSSALKGAIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDD----YLYSICKEPLIELSNPGASGSLFYLT---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCVQSG-GINIRLVVMNN-----------VLPRSVKMHYKYDLKGSTYKRRASRKEREKPCPTYKDLDFV-DMHDGLYFDPETYNALMKT----------LQRDCRVLESFKIMDYSLLLGVHVLDQSHRDGD------------------------------------------------------GSAVDGKRTVGQKVLYSTAMESIQGDGKAAEALTTD--DTMGGIPAKTHRDEKVLIFLGIIDILQSYRFIKKLEHSWKALVYDG-DTVSVHRPS------FYANRFLKFMSSRVFRKNQPNRFSPSK---------------------KARN-SISALKCSSQEVLSSQKEE--KTEEKADRLGGARSLASLD---------GQVLWSYNRPDLVLQTPHPYEASSFSHTLSPPSVFIKDHYLEAK-----SNESRCAC------------------STFTLEDSAIC-------------------------------------------------------LTSEQSTMDIDRDDDSVLDVYF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BCW3-1", "uniprot_id": "A0A8M3BCW3_DANRE", "id": "A0A8M3BCW3-1", "name": "", "aln": "----------------------------------------------------------------------------------------MNNSAVYKMSA-------------TAD-------------EPGGERPQKTVGK--------DHKKLSSEALRGAIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKNYAPLAFRYFRELFGIKPDD----YLYSICKEPLIELSNPGASSSWFYLT---SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNP-RTLLP--KFYGLYCIQCG-GMTIRLVVMNN-----------VLPRSLKMDYKYDLKGSTYKRRASRKERAKSSPTFKDLDFQ-EMHEGLYFDADTYNALMKT----------LQRDCRVLESFKIMDYSLLLGIHVLDRRIRRGG--------------------------------------------------------RGDSRRQGTQKVLYSTARESIQGDGKAPEPVADADDETLGGIPAK-HKDEKLLIFLGIIDILQSYRFIKKVEHSWKALVHDG-DTVSVHRPN------FYADRFLKFMGSTVFKKIHPLRGASSR---------------------RKKS-SIHVCRSASQEVLSTVKEE--SQDERR-----AQSLENLDD--------SEETHSCQKPDVIPSSAGLNPAVSAATLSSASS--LDDVKAEAQTDSESRDDCRASS------------------STLALEDSALAS------------------------------------------------------LNSAPSTPE------SGLDVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q9L5-1", "uniprot_id": "A0A6M3Q9L5_DROME", "id": "A0A6M3Q9L5-1", "name": "", "aln": "-----------------------------------------------MASGDGDTINTIDMDSSSASQAKLAEPS-----NASTDHVGNSSPDLGNRPN-------------RAS--------------SKADKERKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDD----FMMSMCTSPLRELSNPGASGSIFYLT---TDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNP-RTLLP--KFFGLYCLQTSNAKNIRLVVMNN-----------LLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKT----------IQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRK-------------------------PLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAES---EPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDG-ETVSVCRPS------FYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHSHSSGKIHQPAKPPTTEPTPAGAAGGAERGATALGPATTSGASERAPPPVKQRTPAASNLKTRVPPPVPPRGSPRRKDAQDRTTPGTEPHTTNP--NPAPAHTHTLQVPANEG----------IPRFGDRRSPSNVQDWLELHDLFDGPDSGPYGPYAPPAPLADPTVTLLRSSSLRRRDSLHSAYSTARSESSFRRQQPRLLNHVDIFQRKNSFVARSDRSSVGSIVRSFPPIRAESYRTGRSRSSGSIHSQHSPRRGIQEKLQRHQRRKRYFHYVDLALGGEDCENQPEEDNLLQSVSAFLEVKRELEATQRPRRPLPKLTLPDPVVEPARSPPGQQIRRGKRRAPKAAPSTIPESDGTQGSTGRGQGRD--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2R3-1", "uniprot_id": "PI5K1_DROME", "id": "Q9W2R3-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl", "aln": "MDTRVELELEPVGKQDRLKDQPDDENEPLENQLELEQEHKSLLTPVKIPPAQTASPDQEATPSTPPPMSLQPGTSRQLFRDAAMAHGGQETTSLLQQELNNIAATQTPASKLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDD----FLMSMCASPLRELSNPGASGSIFYLT---TDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNP-RTLLP--KFFGLYCFHYN-SKNVRLVAMNN-----------LLPSDIKMHCKYDLKGSSFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMST----------IKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDED--VPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKSILYNG-DTVSVCRPS------FYAKRFQDAMGKQVFKKTPTFPLKHSP---------------------SKRKTSTTQLRSPASRLPPLSTPTNAVRQPIMTMSGMSTPPPAFD----------DISEEDITAASTSSLQQQRSSNQSNNNRGETEVALREGNNTRGGSGEPSSTYHTQYSYDS---------SGRTGSALTSDYSDDES---------------------------------------TGTDLSSRLPKLRTHRLTKTSVQVTTVGYVEGVDTPPKGGQDVVHADVNGKTTMTTTTMLTTTKTAHIQAPSYTSTLVLNDLPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P78356-1", "uniprot_id": "PI42B_HUMAN", "id": "P78356-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "-----------------------------------------------------------------------------------MSSNCTSTTAVAVAP------------------------------LSASKTKT----KKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDN-HLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQD----YQNSVTRSAPINSDSQGRCGTRFLTT---YDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLP--QFLGMYRLTVD-GVETYMVVTRN-----------VFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQK-LHVGEESKKNFLEK----------LKRDVEFLAQLKIMDYSLLVGIHDVDRAEQE--EMEVEERA----------------------------------------EDEECENDGVGGNLLC-SYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFNEFMSNILT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80XI4-1", "uniprot_id": "PI42B_MOUSE", "id": "Q80XI4-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "-----------------------------------------------------------------------------------MSSNCTSTTAVAVAP------------------------------LSASKTKT----KKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDN-HLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQD----YQNSVTRSAPINSDSQGRCGTRFLTT---YDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLP--QFLGMYRLTVD-GVETYMVVTRN-----------VFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQK-LHVGEESKKNFLEK----------LKRDVEFLAQLKIMDYSLLVGIHDVDRAEQE--EMEVEERA----------------------------------------EEEECENDGVGGSLLC-SYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFNEFMSNILT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88377-1", "uniprot_id": "PI42B_RAT", "id": "O88377-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "aln": "-----------------------------------------------------------------------------------MSSNCTSTTAVAVAP------------------------------LSASKTKT----KKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDN-HLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQD----YQNSVTRSAPINSDSQGRCGTRFLTT---YDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLP--QFLGMYRLTVD-GVETYMVVTRN-----------VFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQK-LRVGEESKKNFLEK----------LKRDVEFLAQLKIMDYSLLVGIHDVDRAEQE--ETEVEDRA----------------------------------------EEEECENDGVGGGLLC-SYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFNEFMSNILT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70172-1", "uniprot_id": "PI42A_MOUSE", "id": "O70172-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "----------------------------------------------------------------------------------------MATPGNLGSS------------------------------VLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDN-HLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQD----FQNSLTRSAPLPNDSQARSGARFHTS---YDKRYVIKTITSEDVAEMHNILKKYHQYIVECHGVTLLP--QFLGMYRLNVD-GVEIYVIVTRN-----------VFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQK-IYIDDNNKKIFLEK----------LKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEEND----------------------------------------GEEEGESDSTH------PIGTPPDSPGNTLNSSPPLAPGEFDPNIDVYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFLDFIGHIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0I8-1", "uniprot_id": "PI42A_RAT", "id": "Q9R0I8-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "----------------------------------------------------------------------------------------MATPSNLGSS------------------------------VLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDN-HLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQD----FQNSLTRSAPLPNDSQARSGARFHTS---YDKRYVIKTITSEDVAEMHNILKKYHQYIVECHGVTLLP--QFLGMYRLNVD-GVEIYVIVTRN-----------VFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQK-IYIDDSNKKIFLEK----------LKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEENE----------------------------------------GEEEGESDGAH------PIGTPPDSPGNTLNSSPPLAPGEFDPNIDVYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFLDFIGHILT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48426-1", "uniprot_id": "PI42A_HUMAN", "id": "P48426-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "----------------------------------------------------------------------------------------MATPGNLGSS------------------------------VLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDN-HLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQD----FQNSLTRSAPLPNDSQARSGARFHTS---YDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLP--QFLGMYRLNVD-GVEIYVIVTRN-----------VFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQK-IYIDDNNKKVFLEK----------LKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEEND----------------------------------------GEEEGESDGTH------PVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFLDFIGHILT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXW0-1", "uniprot_id": "B0UXW0_DANRE", "id": "B0UXW0-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "----------------------------------------------------------------------------------------MASAASSLAA------------------------------SIASKTKTEKKKKKQHFVSQKVKLFRASDPLLSVLMWGVNHSINELRHIQIPVMLMPDDFKANSKIKVDN-HLFNKENMPSHFKFKEYCPLVFRNLRERFSIDDQE----YQNSLTRRAPIPSDAQGRSGARFHTS---HNKRYVIKIITSEDVAEMHNILKKYHQYIVECHGNTLLP--QFLGMYRLTVD-GDETYMIVTRN-----------VFSHRLPVYKKYDLKGSTVAREASDKEKTKELPTYKDNDFINDGQK-ICIDDENKKMFLEK----------LKNDVEFLAQLKLMDYSLLVGIHDVERGEQEQPEEESEDNDA---------------------------------------GEEEGTESDGG------ATGSPPDSPSNTLDSNRPLGPGEFDPIIDVYAIKSHENAPKKEIYFMAVIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPE------QYSKRFYDFITTILS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6IQE1-1", "uniprot_id": "PI42C_DANRE", "id": "Q6IQE1-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "aln": "-----------------------------------------------------------------------------------MASLGNSGSASSPMV------------------------------MLAPKTKT----KKRHFMQQKVKVFRASDPMLSVFMWGVNHSINDLNQVPVPVMLLPDDFKANTKIKVNN-HLFNKENLPSHFEFKEYCPQVFRNLRERFGIEDLD----YQASLARSAPMKGDGQGE--GLLFTS---YDRTLIVKQISSEEVADMHNILSEYHQHIVKCHGSTLLP--QFLGMYRITVE-SEDTYLIVMRN-----------MFSHRLLVHRKYDLKGSLVDREASDKEKVKELPTFKDMDFRNNMQK-VYVTEEQKEKMMEK----------LNRDVEFLVKLKIMDYSLLLGIHDVARGERE--EEEAEEPCY---------------------------------------EDDADPENGLAPALQVGSYGTSPEGIAGYMNSIKPLGPGEFDPYIDVYAVKSAPGAPQREVYFMGLIDVLTQYDTKKKAAHAAKTVKHGAGAEISTVHPE------QYAKRFREFISNIFA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38994-1", "uniprot_id": "ITS3_YEAST", "id": "P38994-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase MSS4", "aln": "-----------------------------------------------MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSVPNSNSNPD-------------------------------SNHRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGN--------------------------------------KVSEGHVNFIIAYNMLTGIRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYN---------------HVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKEDDLQLADTAS------------------------------------IEEQPQTQGPIRTGTGTVVRHFFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDTKLVSAIPPRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :: * *: : . . : . : : . : *: . : : * : .. . : ** * . :: * :. . . * . . . . : *. . .. ::.. .:: * *** . . . ::: : : . :* .. * . : . ", "identical_positions": 16, "similar_positions": 63, "identity": "1.37%" }, { "cls_id": "homologset.agr.SGD:S000002619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64350-1", "uniprot_id": "EI2BE_RAT", "id": "Q64350-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "-MAATAAVPSAVGGRANKR---GGG-SGGGGTQGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQK--SKWCHPTSLNVVRIITSDLYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINISKALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVLAVDSTTNRILHFQKTQGLR---HFSFPLG-LFQGSLDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGLLVNEEILGNQIHLHVT-SREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSSTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVVGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVILKPHCVLTSQVVVGPDIILPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGPEGQGYLWKAEDVDEKEDEELRQSLWGLMINMEEESETESERSVDPEELDSRAGSPQLDDIR-------------VFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQVDGVLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVP--SLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWLREAEEESSDDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHW4-1", "uniprot_id": "EI2BE_MOUSE", "id": "Q8CHW4-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "-MAATAAVPGAAAGRASKR---GGGGSGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQK--SKWCHPTSPNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVISNINICRALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVMAVDSATNRVLHFQKTQGLR---RFSFPLS-LFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGILMNEEVLGNQIHLHVT-TREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSTTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVKLKPYCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGLEGQGYLWKAEGVNSKEDEELRQSLWGLMIKTEEESETESEGSVDPEELDSRAGSPQLDDIR-------------VFQNEVLGTLQRGREENISCENLVLEINSLKHAYNISLKEVMQVLTLVVLEFPLQQVDGLLDPNRYCALLLPLLKAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVT--SMAKVLMAFYQLEILAEETILSWFSQRDTTDEGQQLRKNQQLQRFIQWLREAEEESSEDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13144-1", "uniprot_id": "EI2BE_HUMAN", "id": "Q13144-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLK--SKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLR---RFAFPLS-LFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTR-DDFVRGLLVNEEILGNQIHMHVT-AKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIK-------------VFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGI--SMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W541-1", "uniprot_id": "Q9W541_DROME", "id": "Q9W541-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "----------------------------------MAQFEKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVLEQHKRQAKFDKGT-AATLVFKECANNVRT---GNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLD-VFLGN-SCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTR-DDFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYK-LQQEYVFHKDNIYKSPEAHVSKVALLQN-VVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTLAK-TLITRTPSRRRSD------------DEVVVELKSIGPHAYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDFSEDDED-ASRAVTPLPDDTN-------------IFLGEVIDSLTRGFREKSNPDFLVLEINSSRYAYNMSLKEVN--FNVVKAVFGMQSIVEPANDN-VLVAINAAFKQLGPVVSNYIKSEDSMMDCLKALEDVYEENHLVRG--KISQIVHYLYDKDFVSESAIQAWYAQLDEEEHAHLRQSLAKLVAWLDQSSEEDDDEEDDD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32501-1", "uniprot_id": "EI2BE_YEAST", "id": "P32501-1", "name": "Translation initiation factor eIF2B subunit epsilon", "aln": "----------MAGKKGQKK------SGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQINDYIEN--SKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKAS--TYPKTRTIEPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLRTDFVKGVIS-SDILGKHIYAYLT--DEYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQD--DQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAGSR----MYDNESNEQFDQDLDDQTLAVSIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKRRTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVR--IATITALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLT--VKWVEWLQNADEESSSEEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:::*. .* *:: . ****.** :::*:* * :**.*.*: . .*.::: :. : * . *. **.:**:* :.:: ..*:*: .*.::* :: ** *: :*. : * . . . : . ..:* ..* :.* : : :. : .. . . :: :*:* :* * :. : :* :***:*: ***:*:: .::*..:*: : :*. :*.. *. :. *.: ** **:. : .: . * . :**: :. :.: . : : . : :*: :... * :**** .*:**.* : :::: . : .. :.:.:: . * : . :. .:: : : . * . : *: * . :: .:. *. * .: : .. . :* .: . . .: : :. * * : :: *. .:: . : :**:*: : : *:: :** : : : : : :: . :. . . :: : : : *: : . : :*: ::: *..* *: : . . . :. ::: : :::...:: ", "identical_positions": 96, "similar_positions": 249, "identity": "12.89%" }, { "cls_id": "homologset.agr.SGD:S000002620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28480-1", "uniprot_id": "TCPA_RAT", "id": "P28480-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGGYENAVHSGALDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11983-1", "uniprot_id": "TCPA_MOUSE", "id": "P11983-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYENAVHSGALDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17987-1", "uniprot_id": "TCPA_HUMAN", "id": "P17987-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12613-1", "uniprot_id": "TCPA_DROME", "id": "P12613-1", "name": "T-complex protein 1 subunit alpha", "aln": "-----MSTLASPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARESVLIPGYALNCTIASQQMPKKIV--NAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKLRSYHNSSQTK-PE---RSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITILRIDDMIKLNPEDKSGK--SYADACAAGELDG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12612-1", "uniprot_id": "TCPA_YEAST", "id": "P12612-1", "name": "T-complex protein 1 subunit alpha", "aln": "MSQLFNNSRSDTLFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIGDFTVTNDGATILSLLDVQHPAGKILVELAQQQDREIGDGTTSVVIIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSTSVDTLGKETLINIAKTSMSSKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKAVNVLKAHGKSATESLLVPGYALNCTVASQAMPKRIAGGNVKIACLDLNLQKARMAMGVQINIDDPEQLEQIRKREAGIVLERVKKIIDAGAQVVLTTKGIDDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNLEGEETFESSYLGLCDEVVQAKFSDDECILIKGTSKHSSSSIILRGANDYSLDEMERSLHDSLSVVKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFAAALLIIPKTLAVNAAKDSSELVAKLRSYHAASQMAKPEDVKRRSYRNYGLDLIRGKIVDEIHAGVLEPTISKVKSLKSALEACVAILRIDTMITVDPEPPKEDPHDH-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : * : :* :*.***:*: :::*:****:***************.*:******** **:*:***.*:* ***: **.*:*********:*:****.*:****:*****::*:*:*:* :** ::*.* * .* **:: *** *********** :.::*: ***** ::* : :*: *.::::*:*****:* **:*: ******.:.** * *:*. *.******:.***::* :***: * **::*: ** ** .*. **:: *: :*.:*:*.: *:**: :* **** *.*** * **: :*:*:**:::::::*::***:*: : :* . **.* ::.*** ****.*. ::::******.**: ******:**:*.****.** .**.***.*****.***:*:**::.*********** :**:**:**:****:*:::******::* :* ** * . : **** .* *: :***:**:: *:**** * **.::***** :*.:.** . . .: ", "identical_positions": 295, "similar_positions": 163, "identity": "51.75%" }, { "cls_id": "homologset.agr.SGD:S000002622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN63-1", "uniprot_id": "B0BN63_RAT", "id": "B0BN63-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGK--CEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTG-TSK---SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTSLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTE----------VCKAKCAPSKSQAKPVGVKIP------TCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEA----DRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKN--GETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK64-1", "uniprot_id": "AHSA1_MOUSE", "id": "Q8BK64-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGK--CEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTG-TSK---SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTNLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTE----------TCKAKSAPSKSQAKPVGVKIP------TCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEA----DRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKN--GETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95433-1", "uniprot_id": "AHSA1_HUMAN", "id": "O95433-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVQVQNEEGK--CEVTEVSKLDGEASINNRKGKLIFFYEWSVKLNWTG-TSK---SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTNLVALMKEEGVKLLREAMGIYISTLKTEFTQGMILPTMNGESVDPVGQPALKTE----------ERKAKPAPSKTQARPVGVKIP------TCKITLKETFLTSPEELYRVFTTQELVQAFTHAPATLEA----DRGGKFHMVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTFIDKN--GETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N9S3-1", "uniprot_id": "AHSA2_MOUSE", "id": "Q8N9S3-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 2", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATIWSKGKLRELLVGIAMENEAGR--CEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG-TVKE--SGAKHKGLIEIPSLSEENEINDTEVNVSK-KKGD-GEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAVATQELTLQRKLNEN----------KLQ-------ASPVALGVRIP------TVALHLTELFDTTVEQLYSIFTVKELVQKFSKSPAVLEA----ERGGKFQMFDGNISGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAP--GQTELQLDCKGVPVCKEENMKFCWQKQHFEEIKGLLELTAQNA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7W5-1", "uniprot_id": "A0A0G2K7W5_RAT", "id": "A0A0G2K7W5-1", "name": "", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATVWSKGKLRELLVGLAMENEAGR--CEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG-TVKE--SGAKHKGLIEIPSLSEENEVNDTEVNVSK-KKGD-GEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAGATQALTLERKLTEN----------ALQ-------ASPVALGVRIP------TVALHLTELFDTTVEQLYSIFTVKELVQGFSKSPAVLEA----EKGGKFQMFDGNITGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAP--GQTELQLDCKGVPVCKEEHMKFCWQKQHFEEIKGLLQLTTQNA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q719I0-1", "uniprot_id": "AHSA2_HUMAN", "id": "Q719I0-1", "name": "Putative activator of 90 kDa heat shock protein ATPase homolog 2", "aln": "MAKWGQGNPHWIVEEREDGTNVNNWRWTERDATSLSKGKFQELLVGIVVENDAGR--GEINELKQVEGEASCSSRKGKLIFFYEWNIKLGWKG-IVKE--SGVKHKGLIEIPNLSEENEVDDTEVSLSK-KKGD-GVILKDLMKTAGTAKVREALGDYLKALKTEFTTGMILPTKAMATQELTVKRKLSGN----------TLQVQ----ASSPVALGVRIP------TVALHMMELFDTTVEQLYSIFTVKEL--------------------------------------TNKKIIMKWRCGNWPEEHYAMVALNFVPTL--GQTELQLK-EFLSICKEENMKFCWQKQHFEEIKGSLQLTPLNG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9Q4-1", "uniprot_id": "Q9V9Q4_DROME", "id": "Q9V9Q4-1", "name": "Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein", "aln": "MAKWGEGDPRWIVEERPDATNVNNWHWTEKNATPWSKDRLHQLFQDFKIGQSDIE--CAVDSVDKCSGEATVNNRKGKLIFFYEWELVLKWSGKLLKN--SKLIHKGKLTIPNLSEENELADVEITVTIDESNDESETLKQFMYNVGRDRVRQQLASYIRELKEEYSKNLILPKKGDEAGAGNTVANFKDANNTRNAAQNIALNSSVAAPRLKNSGIGCKLD------VRTLSMTEEFHCSANDLYNALTKPEMVTAFTRAPAKVDA----VRGGEFILYGGNVLGKFEELVPEKKIQQSWRLKNWTSGHYSNVVIELEETS--SSTMMSLKQTGIPASEFDAMKTNWYRYYWHSIKQTFGFGTSISDAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12449-1", "uniprot_id": "AHA1_YEAST", "id": "Q12449-1", "name": "Hsp90 co-chaperone AHA1", "aln": "----------MVVN------NPNNWHWVDKNCIGWAKEYFKQKLVGVEAGSVKDKKYAKIKSVSSIEGDCEVNQRKGKVISLFDLKITVLIEGHVDSKDGSALPFEGSINVPEVAFDSEASSYQFDISIFKETSELSEAKPLIRSELLPKLRQIFQQFGKDLLATHGNDIQVPESQVKSNYTRGNQKSSFTEIKDSASKPKKNALPSSTSTSAPVSSTNKVPQNGSGNSTSIYLEPTFNVPSSELYETFLDKQRILAWTRSAQFFNSGPKLETKEKFELFGGNVISELVSCEKDKKLVFHWKLKDWSAPFNSTIEMTFHESQEFHETKLQVKWTGIPVGEEDRVRANFEEYYVRSIKLTFGFGAVL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * ***:*.:::. :. :: : . . . : .:.. .*:. ..****:* ::: : : * . * .:* : :*.:: :.. . :. :: . . :: :*: . : * . .: :* : . :: : : * . .:** : : :::: *: .*. . : : : : .* : :. :. : : : : . : . ** : . ", "identical_positions": 27, "similar_positions": 98, "identity": "7.3%" }, { "cls_id": "homologset.agr.SGD:S000002625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKV2-1", "uniprot_id": "A0A8I6AKV2_RAT", "id": "A0A8I6AKV2-1", "name": "TP53-binding protein 1", "aln": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQALEEDA-GSHFSVLSRHLPNLQMHKENPVLDIMSNPEQTVAEQ-GDSNSSFSEHLKEKKASDPVESSHLGTSGPISQVIERLPQPNRTSSALGVTVEAASLAEEEKEEE-LEEEKEEVGVNAPDADPRSLAEDSASSQLGFGVLELSQSQDVEEHTVPYDVKQEHLQLVTTNSGSTQLSDVDANTDGKAIKCEEQSTDAISIIE-PSKDIPVTVQPSKGSHVVEEQNLPLVRSEDLPSSPQVSVAAVETKEQVPAQELLEGGLQVQVSSEPEVSSTQEDLFDQSSKTAS-DGCSTPSREEGGCSPVSTPATTLQLLQLSGQKPLVQESLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQGQRKDEPMDMSVIPE-GGEHFQK-LQDDEAVDIEKPLLPSQPAVSPQASTPVSRSTPVFTPAS-LPIPSQPEFSHDIFIPSPSLEEPSNDVEKGGGLHSSSLTVECSKTSESEPKNFTDDLGLSMTGDSCKLMLSTSECSQSSKMESLGSPRTEEVGENTQVEDTEPSSPVTKSK-LPAESESVLVNPTQDDQVEMSQNVDKAKEDEVEDRGDVDVLAAGCKGREDMVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEEFSGSEVEEVPETPCGSHREESKEEPMESIPLHLSLTETQSEALCLQKEAPKEECPEAMEVETSVISIDSPQKLPVLDQELEHKDPETWEEATSEDSSVVIVDVKEPSPRVDISCEPVEGVGKCSDSQSLEGAAPEEEPCAENRLNTPEEKRVECDGDSKAETTEKNSVTEDSPQPPLPSVR-DEPVRPDQELQQPQVQEKES-PVTLDAKVADDKHLGSEGSCQQLEKAPARASQSFCESSS----------------------------------------GISNYPESTIATSDVMSESMVEINDPLLGNEKGDSESAPEMDGKLSLKMKLVSPETEASEESLQFSLEKPTTAERRNGSTAIAEPVASPQKPMSVFGCIYEAQQEEEAQSGDPPSTPVRTNLLHFPSAQ-EEDREEPDATPQLRQSEQPVKLIGPVKDAAASEDSASSVSQQRASQG------SLSPQEEVMEADLLEGLGANQDRPSKILMERPTQSNIGIQTMDHSLCAPETVSAATQTVKNVCEQGTSTVEQNSGKQDATVQTERGSGEKPASAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHTRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSSHHTSSGTSLSAIHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGISQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETVVSGPLGIEDTSPSMSPDDKSFTRIMPRVPDSTKRMDASSGALRRSDSPEIPFQAATGSSDGLDSSSSGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSTTPTRKTTESPRASMGVPSGKRKLTTSEEERSPAKRGRKSATVKPGTVGAAELVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFQQHPKYKHDYVSH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70399-1", "uniprot_id": "TP53B_MOUSE", "id": "P70399-1", "name": "TP53-binding protein 1", "aln": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDA-GSHFSVLSRHLPNLQMHKENPVLDIVSNPEQSAVEQ-GDSNSSFNEHLKEKKASDPVESSHLGTSGSISQVIERLPQPNRTSSALAVTVEAASLPEEEKEEEELEEEKEGVGANAPGADS-LAAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHLQLVTTNSGSSPLSDVDAST---AIKCEEQPTEDIAMIEQPSKDIPVTVQPGKGIHVVEEQNLPLVRSEDRPSSPQVSVAAVETKEQVPARELLEEGPQVQPSSEPEVSSTQEDLFDQSSKTAS-DGCSTPSREEGGCSPVSTPATTLQLLQLSGQKPLVQESLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQGGRKDEPMDMSVIPV-GGEPFQK-LHDDEAMETEKPLLPSQPAVSPQASTPVSRSTPVFTPGS-LPIPSQPEFSHDIFIPSPSLEEPSDDVKKGGGLHSSSLTVECSKTSESEPKNFTDDLGLSMTGDSCKLMLSTSEYSQSSKMESLGSPRTEEDRENTQIDDTEPLSPVSNSK-LPADSENVLVTPSQDDQVEMSQNVDKAKEDETEDRGD-------CKGREDAVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMDTKEHHPEEGFSGSEVEEVPETPCGSHREEPKEEPMESIPLHLSLTETQSEALCLQKEAPKEECPEAMEVETSVISIDSPQKLQVLDQELEHKDPDTWEEATSEDSSVVIVDVKEPSPRADVSCEPLEEVEKCSDSQSWEGVAPEEEPCAENRLDTPEEKRIECDGDSKAETTEKDAVTEDSPQPPLPSVR-DEPVRPDQETQQPQVQEKES-PVTVDAEVADDKQLGPEGACQQLEKAPACASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVTSESMVEINDPLLGNEKGDSESAPEMDGKLSLKMKLVSPETEASEESLQFSLEKPTTAERKNGSTAIAEPVASLQKPVPVFGCIYEAQQEKEAQSEAPPSAPDRANLLHFPSAQ-EEDKERPDVTPKLRQSEQPVKPVGPVMDDAAPEDSASPVSQQRASQEQRASQEPFSPAEDVMETDLLEGLAANQDRPSKMLMDRPTQSNIGIQTVDHSLCAPETVSAATQTVKSVCEQGTSTAEQNSGKQDATVQTERGSGEKPASAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSSHHTSSGTSLSAIHSSGSSGRGAGPLKGKASGTEAADFALPSSRGGPGKLSPRKGISQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETVVSGPLGVEDISPSMSPDDKSFTRIMPRVPDSTKRTDASSSTLRRSDSPEIPFQAATGSSDGLDSSSSGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPVTPTAASSSSTTPTRKATESPRASTGVPSGKRKLPTSEEERSPAKRGRKSATVKPGTVGAAEFVSPCETGDNIGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12888-1", "uniprot_id": "TP53B_HUMAN", "id": "Q12888-1", "name": "TP53-binding protein 1", "aln": "-----MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDS-GSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANT---AIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGS-LPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGE-------AMVTDVLE-DQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z753-1", "uniprot_id": "A0A8M6Z753_DANRE", "id": "A0A8M6Z753-1", "name": "TP53-binding protein 1", "aln": "-----MDPGESDLDSSFPQTENPCLIVEDSQPDSVALEDDPDTSYCALLARRLSNLQPTSQSPVLELISSPTKSCCLQTGSQIDKGGNTAHSDNLQNNLGSAATEHS----QVFEVCSLP--------------------------VSKRTVTEHMESEANSTTHCTEAHEEMSQFGLLELSESQGVFEEDDLDGANKKNVQKPTSQYVLKSSERVLSNK--------------------------------------DGNSTGSEVTSSCPLKPQDGESRKLSIQAILHSQLPDS----QEDEEDVLVSSQDDMFEKETNGTKADSSVS------EHLPTSTPAQSLRLLHLSGQGTYVQESLSQQSVDFVAATQDNLSQTPYIVPNSPTEKDQNCNETAESPMDTSAPPEDQPQ-GREEEPMDTDPCPKP-----QPTASTPVSQNSPGFILEKRLSVPSQPEFSHDVFISTPSLEPVNNNQGTEASKRQLPHPNCTSATESTPPKPSSPEEQLNKSSSSFSQPCEAAEDFQLELSSENSCFALKT--QSFIVEEDSQATQIQDQGTVVTDKSNSSPKPHSQNEDKNSTDSEPSKASNSNVPDS------KITSAVPEKAEDLNISQKLNNGGNQIAN-ATPGATLSQLSVSSECVSATPNLPQTSKSTDAGCPQASPLTDKPATPVPVAQHTQSQSVLTASSQKNTGNKEKHDGQNQRLSQPMLHSHSVTTDSVRN----VEEEEQMEEGEIKSTVKGDDTGINLALSQSQALSPEPMEEEEEKGEASIRSSSREESFSVMVLEESQRVSQEKVQ------------KGKSPPFKSSSQPVSGSIQ-DKPEALAKISGSQPVSSTKVSPLRLEKTKSQNTQPSSSG--QQKVNSDNAANKSLSDSSGELPFHFTLPKEGELIRPAVSATPPQISLLKKTP-RHSTPIEMNSFSEPSVG--DVTRETMANSEISVEESREGEEPVAAEQDGKLSLRMKLVTPVEEGSSGPECFSLQKPSLTD-EEGSVSKATAVAMAVTSPSVFSRVREVHRQTQVEDDAESSDPLIRQPSQLLSPTITNDSE-----------------LSPNCPKETSNSSRASVTEAVSLNPG--------ALEADSEALVSGLLSPAREREALDTFDRP-QTPVRKKAVSQQTSVDISSTTSPPSKKAVSQQTSFDLS---GPHNLSGRGEPSTPTRTQPVPS------------------------LRRHVRTIQEVRTTVTRIITDVYYEDGREVNRKVTQESEEPVVDRCVVENDISPSRTGSSMTSGDLADVSSLSSKAP-SHHSSSGTSSGGLGPIRMPDFLMPPSRGAKFGRSLCVFNP---RRGGRQQQPRTLTLVVGSEVTDARGSR-------VSTQLSPRGRARRGRPPSRGGRPGQRGGAHAPGGASSS-----EEEPFAQRHVQMPISPVEPSATS-------------HSESLNTTSPDNSTGSSSFVGLRVLAKWSSNSYFYSGSITRDLGENRFRLLFDDNQECEVQGKDILLCDPIPLETEVTALTEEEYFNIGVVKGHKTQGSEFLYCVEKDGQSSYYSRTSVILSMEQGSRLREQYGLGPYEPSTPQTMACDISLDNLVEGKRRRRGNCSGAGTPTRSSSNSPR-----------NPGPSGKRKLISCTEEERTPPKRGRRGAGARVGRR-IAACNTSGSGVDLPPDPNDLVATHGPLPENSSLFMGFVFLLTASSEGDRYSSHQ--------SSDEDEEYVQRAPYNKHYTVSQLEAGGGMILLDFNEEQCKAAYQSLLIADQHCRTRKYLLCVAGGVPCVSQMWVRDCCQEKKLLNYRNYLLPAGLGPG-GRIVEWHPRSNPFKALKVMLIAEDR---VDLWTSLLSMGGAEKVYRQES-QNISDIPDVKFDVAVTSSACTSEEVKR-VASDMPVVSLEWLIQSLICGKCLNFDSNSEFCHNTST-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14737-1", "uniprot_id": "RAD9_YEAST", "id": "P14737-1", "name": "DNA repair protein RAD9", "aln": "--------------------------------------------MSGQLVQWKSSPDRVTQSAIKEALHSPLADGDMN--------EMNVPVDPLENKVNS-----------------------------------------------TNIIEGSPKANPNPVKFMNTSEIFQKSLGLLDESPRHDDELNIEVGDNDRPNANILHN-------------------------------------------------------------------------------------------------ERTPDLDRIANFFKSNR----------------------TPGKENLLTKYQ-------------SSDLEDTPLMLRKKMTFQTPTDPLEQKTFKKLKSDTGFCYYGEQNDGEE-----------------------NASLEVTEADATFVQMAERSADNYDCALEGIVTPKRYKDELSKSGGMQDERVQKTQIMISAESPNS--------------------------ISSYDKNKITGNGRTTRNVNKVFNNNEDNIGAIEEKNPVKKKSENYSSDDLRERNNQIIQSNESEEINELEKNLN--------VSGRENDVNNLDIDINSAVSGTPSRNNAEEEMYSSESVNNREPSKKWIFRYSKDKTENNSNRSTQIVNNPRTQEMPLDSISIDTQPLSKSFNTETNNELETQIIVSSLSQGISAQKGPVFHSTGQTEEIKTQIINSPEQNALNATFETPVTLSRINFEPILEVPETSSPSKNTMSKPSNSSPIPKEKDTFNIHEREVETN---------------NVFSNDIQNSSNAATRDDIIIAGSSDFNEQKEITDRIYLQLSGKQISDSGSDETERMSPNELDTKKESTIMSEVELTQELPEVE----------------------------------EQQDLQTSPKKLVVEEETLMEIKKSKGNSLQLHDDNKECNSDKQDGTESLDVALIEHESKGQSSELQKNLMQLFPSESQEIIQNRRTIKRRQKDTIEIG------EEEENRSTKTSPTKHLKRN----------------------------------------SDLDAASIKREPSCSIT---------------------IQTGETGSGKDSKEQSYVFPEGIRTADNSFLSKDDIIFG----NAVWCQYTWNYKFYPGILLEVDTNQDG--------------------------------------CWIYFETGRSLTKDE-DIYYLDIR-IGDAVTFDGNEYVVVGLECR-------------SHDLNIIRCIRGYDTVHLKKKNASGLLGKRTLIKALSSISLDLSEWAKRAKIILEDNEKNKGDAYRYLR--------------------------HPIRGRKSMTNVLSPKKHTDDEK--------------------------------------------------------DINTHTEVYNNEIESSSEKKEIVKKDSRD------ALAEHAGAPSLLFSSGEIRTGNVFDKCIFVLTSLFENREELRQTIESQGGTVIESGFS---------------TLFNFTHPLAKSLVNKGNTDNIRELALKLAWKPHSLFADCRFACLITKRHLRSLKYLETLALG---------------------WPTLHWKFISACIEKKRIVPHLIYQYLLPSGESFRLSLDSP---------------SKGGIIKSNNIFSFYTQFLRGSNLRDQICGVKKMLN-------------------------------DYIVIVWGR------------SELDSFVKFAFACLSAGRMLTIDLPNIDVDDTEPLLNALDSLVPR------------IGSELSNRKLKFLIYANEN-------------NGKSQMKLLERLRSQISLKFKKFNYIFHTE------------------SKEWLIQTIIN-EDTGFHDDITDNDIYNTISEVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : .. : .:..: : : .* : . : : * . . : :*:*: * :. . .: : : . . . ::*... **. * : . * *: .. . .: .*..* *: . : . : : ** ::. . * . . ..:. .. : ... . . : : . . . . :. :: . : .. : .... : : : . : : .: : . . .::: *. . .. . * *. . * . . : . .. *: : . : : . .: : . . . : : : : : . . : : : : *.. : .. :.* . : . : . :: .. . : :. :. .: :. :.. .: : :. * . .: .... : . *.. .* : *: :... .* : : .: . : ..: : .: : . . : : . . . . ::. :: . . . : * * : . * : . *. :*: *:** * : ** : :* :* . * ** : .: . . :....:. . . . . : . * * : * . .*.: : . .* .:: * * : ::.. * : .: :* .* *:: .: : * : :. . : .*. : .: *: : .. : *. . .* : .* : *: :: * : . : : : *:: : * :. :* : ...:* :. :* :. *: .. . . *: :.. :: .. .: : *::.* . .: * . : * * : *:* . . : **.:: :::. .* .: . .: *: . * **:** :* : .*... . : ", "identical_positions": 90, "similar_positions": 382, "identity": "4.51%" }, { "cls_id": "homologset.agr.SGD:S000002626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16181-1", "uniprot_id": "SEPT7_HUMAN", "id": "Q16181-1", "name": "Septin-7", "aln": "MSVSARSAAAEERSVNS-------------------------STMVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYS--PEYPGPSHRIKKTVQVE-------------------------QSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNR-RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFP----------------ETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR-GRQYPWGVAE----VENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNS--SRTLEKNKKKGKIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZC4-1", "uniprot_id": "A0A8M1NZC4_DANRE", "id": "A0A8M1NZC4-1", "name": "Septin", "aln": "----------------------------------------------MAQKNLEGYVGFASLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYS--GEYPGPSNRIKKTVQVE-------------------------QSKVLMKEGGVQLLLSIVDTPGFGDAVDNSNCWQPVIDHIDSKFEDYLNAESRVNR-RQMPDSRVHCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMREILEHKIKIYEFP----------------ETDDEEENKIVKTIKDRLPLAVVGSNTIIEANGKKVR-GRQYPWGVAE----VENGDHCDFTLLRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTCNGIDNNKAKGQLTKSPLAQMEEERREHVTKMKKMEMEMEQVFEMKVKEKVQKLKDSEGELQRRHEQMKKNLEAQHKELEERRRQFEEERSTWETQQRILEQQK----MTLEKNKKKGKIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PMV4-1", "uniprot_id": "A0A8M9PMV4_DANRE", "id": "A0A8M9PMV4-1", "name": "Septin", "aln": "MRLQETENHAEKGMEKDSIQLDKALTVIWSEIHCLHDDIELMMELIQNQRNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYS--KDYPGPSQRIKKTVQVE-------------------------QSKVLIKEGGVQLTLTIVDTPGFGDAVDNSNCWQPVINYIDSKFEDFLNAESRVNR-RQMPDNRVHCCLYFIAPSGHGLKPLDIEFMKRLHDKVNVIPLIAKADTLTPEECQLFKKQIMKEIQEHKIKIYEFP----------------DTEDDEDSKLIRKIKEKMPLAVVGSNVVIEVNGRKVR-GRQYPWGVAEEGIVVENGEHCDFTVLRNMLIRTHMQDLKDVTNNVHYENYRSKKLAAVTCNGVDATKNKGQLTKSPLAQMEEERREHVMKMKKMETEMEQVFEMKVKEKKQKLKDSEAELERRHEQMKKNLEAQYKELEEKRRQFEDEKANWEAQQRILEQQKLDASKTMEKNKKKGKIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04921-1", "uniprot_id": "SPR28_YEAST", "id": "Q04921-1", "name": "Sporulation-regulated protein 28", "aln": "------------------------------------------MFPMKDHSALEQHT--LSRDELRRRKGYKKGLQLSILLLGEKGSGKSTFLNNLCGQDISLSDGDYDDDDDKVTNNVTPENGNAIEDIDPGYKTAHLSPGLKLVTRRVYLNDELGVPITLDIILFPGCGDNVDNSQSSVVIKNYLDQQFANVLKEEVRIKRNTKETDGRPHVCLYFLKSTPRGVKKFDIELMKTICDKVNLIPIIPKADGLTETELNLHKDIVRQEISQNNIRVFDFKSDTLGETLALYDMDIDSSSAKSKYDNDTKIKEISPFAIVCSKTFNKNSENRVEHIRTYEWGSLV----VEDQNTSDFIYLKAILLGSHLQELKDVTNNVLYENYRAKVLTEKKNN----------YDIPNYSYIDETSRGSVS-------------------NVSTRRNSASRTLGNPDTNDENAYQIHKEIDEKNRIIEDYQRKIDLLEKMLAAPH--------QNKV-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :. . : **. *:*::::::::**.* ****::*.* *: :* . ..::.:.* * : * .* ** : * *: ** ** ****:. : :::*.:* : *: * *::* : .*.* : ****: .: :*:* :***:** : :***:**:*.*** ** * : .*. : :** :::*::::* .:. ... . .**: *:*:* *:.. : . .:*. * * ** **: : .** *: :*: :*:*:******** *****:: *: . * . : ::* * * : .. ::* .. . : .:* :**::*:.* :*: : . : :::* : :** ", "identical_positions": 116, "similar_positions": 135, "identity": "22.61%" }, { "cls_id": "homologset.agr.SGD:S000002629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08795-1", "uniprot_id": "GLU2B_MOUSE", "id": "O08795-1", "name": "Glucosidase 2 subunit beta", "aln": "------------------------------------------------MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYEE----SKPFTCLDGTATIP-FDQVNDDYCDCKDGSDEPGTAACPN--------------GSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDE-------YNSGTVCENTCREKGRKEKESL------QQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAK----------------------------------------------------------EEAERPEKEAKDQHR-KLWEEQQAAAKARRE-------------QERAASAFQELDDN-----MDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYR------SEVPPTDIPVP---EETEPKEEKPPVLP-PTEEEEEEEEEPEEEEEEEEEE-----EEAPPPLQPPQPPSPTEDEKMPP-YDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQ------KPKHGGSPTSLGTWG-----------SWAGPDHDKFSA----------------------------------MKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEAPSDGDHDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADW9-1", "uniprot_id": "A0A8I6ADW9_RAT", "id": "A0A8I6ADW9-1", "name": "Glucosidase 2 subunit beta", "aln": "-------------------------------------------------MLLLLLLLPLCWAVEVKRPRGVSLSNHHFYDE----SKPFTCLDGTATIP-FDQVNDDYCDCKDGSDEPGTAACPN--------------GSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDE-------YNSGTVCENTCREKGRKEKESL------QQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRTAK----------------------------------------------------------EEAERPEKEAKDQHR-KLWEEQQAAAKARRE-------------QELAASAFQELDDN-----MDGLVSLAELQTHPELDTDGDGGLSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYR------SEVPPTDIPVP---EVTEPKEEKLPVLP-PMEEEEEEEEPEEEEEEEEEEVPGEQPKEVPPPQQPLRPPSPAEDEKMPP-YDEETQAIIDAAQEARNKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQ------KPKHGGSPTSLGTWG-----------SWAGPDDDKFSA----------------------------------MKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEVPTDGDHDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14314-1", "uniprot_id": "GLU2B_HUMAN", "id": "P14314-1", "name": "Glucosidase 2 subunit beta", "aln": "------------------------------------------------MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDE----SKPFTCLDGSATIP-FDQVNDDYCDCKDGSDEPGTAACPN--------------GSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDE-------YNSGVICENTCKEKGRKERESL------QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK----------------------------------------------------------EEAEKPEREAKEQHQ-KLWEEQLAAAKAQQE-------------QELAADAFKELDDD-----MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR------SEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEE--EDSEEAPPPLSPPQPASPAEEDKMPP-YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQ------KPKLGGSPTSLGTWG-----------SWIGPDHDKFSA----------------------------------MKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBI5-1", "uniprot_id": "A0A8M2BBI5_DANRE", "id": "A0A8M2BBI5-1", "name": "Glucosidase 2 subunit beta", "aln": "MPTRHLKDGVNVYQTAGKKCKFFKLFRSRASSGTQCLFLHLGIMTCVHLLLTLVFAVSLGTPVEVHRPRGVPLSKKPFYEE----NKPFTCLDGSKTIL-FDQVNDDYCDCKDGSDEPGTAACPN--------------GKFHCTNAGYKPTFIPSSRINDGICDCCDTTDE-------YNSGAKCENTCKELGRKEREVL------QKMAEITKEGFLLKQQLIEEAKKGRGEKQSKVTEMQDNKKQLEEKVEALRTVK----------------------------------------------------------ETAEQPEREAKERHL-KAWEEQKAAIRLVKD-------------KAKMAEAFLELDDN-----ADGLVSVSELQSHAELDSDTDGTLSEAEAKGLMGGVEQVDTATFES-VWENIKDKYH------SESQP-EEPAP---VETPVDEVKEPVVDNESEPYPEDISEEEDEDDDDDDEYHEEDEKAPPTMKTPE-KSQEDEEAMPP-YEADTQVLIEAAQKARDDFEEAEKALREMDDQIRNIEKELSFDFGPNAEFTYLYSQCYELSTSEYIYRLCPFNRVSQ------KPKFGGSETNLGTWG-----------SWSGPENNKYLS----------------------------------MKYEHGTGCWQGPNRSTTVKLTCGKETMLTSTSEPSRCEYLMEFITPAVCQEPSNIDLSAHGHTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJD1-1", "uniprot_id": "Q9VJD1_DROME", "id": "Q9VJD1-1", "name": "Glucosidase 2 subunit beta", "aln": "---------------------------------MQSLQLS---QVLLIPLLLALVATNVGSASEVPRPLGVPLAKASLYQPR-AGENSWTCLDGSRTIP-FSHINDDYCDCADGSDEPGTAACPQ--------------GQFHCVNKGHQPVNIPSSQVQDGICDCCDGSDE-------SET-VGCPNTCLELGAAAAVQR------RNAAELHKRGAERRQEMITRGKQMRAEREARRLELDQRRKEQELLRAEKEQLK----------------------------------------------------------QTAEALEAEAIEIFKEQQREVDADTAQAEREPQQ---------MRQEATLTFVRYDTN-----KDGFVEVTELMVDMNLDRDRNGVVTVEEAKYFLDERERVDLDAFVTLAWPRIKSLQM------LAEGLFQPPQPEE-VAQQPEVTTESIQPTPPKLSEEQAELAGDDDIEADEEGEEDQYDDEEPDVGVGEASPDAEEATPPNYDPETQRLIQQANEARNALEEVERSLREIQQEVNEIDDQNNKGYGLTEEWAVHDGQCYNFEDREYVYTLCPFDRASQ------KSRSGGPETTLGRWD-----------KWSG-EPKQYSQ----------------------------------QKYTNGAACWNGPNRSAIINISCALEPKITAVSEPNRCEYYFEFETPAACDSEAFQSESENLHDEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04924-1", "uniprot_id": "GLU2B_YEAST", "id": "Q04924-1", "name": "Glucosidase 2 subunit beta", "aln": "----------------------------------------MVSMFSLFLLLIEQSPLVASLQQSQRHIVGVPWEKQHLYDSNEPDLTKWHCLNHEDIVLDISQINDGVCDCPDGSDEPGSAACVEDIFKSVAEGGGKVNKYFYCDNKGFIPRYIRKSEVADGICDCCDCSDELLSGYELFDAGSNCSQLKNEFDIMASKELSSYREGKEALEELERKYGTKEEAITRGNCLEEDKEKASAEIKVLSNRLSENRAKLEQLRGEYFNQLSHDPILYQFEQLNSTRLGSDILTSFTMVSRVSKGYQDIFKILSDLSEAYTPSLNDKVVNDNIKKFRKVRRRAEKAKINADSKIDDEQADNLYLYFTEEVPQIFLKRESENTLRYVIGKSNFVQALVEGKINYTNDILEYIREFRLIMDDISQNYNVNFQDAGVKSAVDSYKNYLGEYGELAELEPAHPSESLLRSLSEVTSFVNENAPKVLPPDAVESEQDTNSDHIGTSGDLRNKLKEILSKLNIFSSRKDLVSL--EKRFRSCESQVSLLENELKQKMDYKKLLDETEDEGTNSTAGNLTELLELMGSQSYCLDDILDNYVYTICFQRPMTEGVIYQAEDKVDGKKVLIGRFKTSGFNVDLNMEKYAEHLKATYDEKSDLISNLAAIQDDDGNMQHYVFGNLNELNNGLVLEYENGDQCWNGPRRSATVFVRCSDKFKIRSVHEATKCNYIFDVVGPLGCNKTFEYEPPKFNLSE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . : **. : :*: . : **: : :.::**. *** *******:*** : *:* * *. * * ...: **:***** :** :: * : * . :: * .. :: * : . ::: *:. : . . : . : : . . . : . . . * . : : * .. : . ::: : * : ::. : * . : . * . : : : :: . . . .: . : : . .. .. ::: : ::: . .. . * . * : :*:* :* :: : : .* . :* : .: : :* :* **:**.**: : : *. : : :. *..:*:* ::. * * . . * ", "identical_positions": 68, "similar_positions": 143, "identity": "9.13%" }, { "cls_id": "homologset.agr.SGD:S000002632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00729-1", "uniprot_id": "H2B1A_RAT", "id": "Q00729-1", "name": "Histone H2B type 1-A", "aln": "--MPEVSAKGTTISKKGFKKAVTKTQ----KKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKA--MSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70696-1", "uniprot_id": "H2B1A_MOUSE", "id": "P70696-1", "name": "Histone H2B type 1-A", "aln": "--MPEVAVKGATISKKGFKKAVTKTQ----KKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKA--MSIMNSFVTDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A08-1", "uniprot_id": "H2B1A_HUMAN", "id": "Q96A08-1", "name": "Histone H2B type 1-A", "aln": "--MPEVSSKGATISKKGFKKAVVKTQ----KKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA--MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWY9-1", "uniprot_id": "H2B1C_MOUSE", "id": "Q6ZWY9-1", "name": "Histone H2B type 1-C/E/G", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62807-1", "uniprot_id": "H2B1C_HUMAN", "id": "P62807-1", "name": "Histone H2B type 1-C/E/F/G/I", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64478-1", "uniprot_id": "H2B1H_MOUSE", "id": "Q64478-1", "name": "Histone H2B type 1-H", "aln": "--MPE-PAKSAPAPKKGSKKALTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58876-1", "uniprot_id": "H2B1D_HUMAN", "id": "P58876-1", "name": "Histone H2B type 1-D", "aln": "--MPE-PTKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10854-1", "uniprot_id": "H2B1M_MOUSE", "id": "P10854-1", "name": "Histone H2B type 1-M", "aln": "--MPE-PTKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99877-1", "uniprot_id": "H2B1N_HUMAN", "id": "Q99877-1", "name": "Histone H2B type 1-N", "aln": "--MPE-PSKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10853-1", "uniprot_id": "H2B1F_MOUSE", "id": "P10853-1", "name": "Histone H2B type 1-F/J/L", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99880-1", "uniprot_id": "H2B1L_HUMAN", "id": "Q99880-1", "name": "Histone H2B type 1-L", "aln": "--MPE-LAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGP2-1", "uniprot_id": "H2B1P_MOUSE", "id": "Q8CGP2-1", "name": "Histone H2B type 1-P", "aln": "--MPE-PVKSVPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64475-1", "uniprot_id": "H2B1B_MOUSE", "id": "Q64475-1", "name": "Histone H2B type 1-B", "aln": "--MPE-PSKSAPAPKKGSKKAISKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99879-1", "uniprot_id": "H2B1M_HUMAN", "id": "Q99879-1", "name": "Histone H2B type 1-M", "aln": "--MPE-PVKSAPVPKKGSKKAINKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64524-1", "uniprot_id": "H2B2E_MOUSE", "id": "Q64524-1", "name": "Histone H2B type 2-E", "aln": "--MPE-LAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIANEASRLAHYNKRSTITSREIQTSVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06899-1", "uniprot_id": "H2B1J_HUMAN", "id": "P06899-1", "name": "Histone H2B type 1-J", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGP1-1", "uniprot_id": "H2B1K_MOUSE", "id": "Q8CGP1-1", "name": "Histone H2B type 1-K", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60814-1", "uniprot_id": "H2B1K_HUMAN", "id": "O60814-1", "name": "Histone H2B type 1-K", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64525-1", "uniprot_id": "H2B2B_MOUSE", "id": "Q64525-1", "name": "Histone H2B type 2-B", "aln": "--MPD-PAKSAPAPKKGSKKAVTKVQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QNW6-1", "uniprot_id": "H2B2F_HUMAN", "id": "Q5QNW6-1", "name": "Histone H2B type 2-F", "aln": "--MPD-PAKSAPAPKKGSKKAVTKVQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q93079-1", "uniprot_id": "H2B1H_HUMAN", "id": "Q93079-1", "name": "Histone H2B type 1-H", "aln": "--MPD-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23527-1", "uniprot_id": "H2B1O_HUMAN", "id": "P23527-1", "name": "Histone H2B type 1-O", "aln": "--MPD-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q16778-1", "uniprot_id": "H2B2E_HUMAN", "id": "Q16778-1", "name": "Histone H2B type 2-E", "aln": "--MPE-PAKSAPAPKKGSKKAVTKAQ----KKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZNZ9-1", "uniprot_id": "D3ZNZ9_RAT", "id": "D3ZNZ9-1", "name": "Histone H2B", "aln": "--MPE-PSRSTPAPKKGSKKAITKAQ----KKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2U9-1", "uniprot_id": "H2B3A_MOUSE", "id": "Q9D2U9-1", "name": "H2B.U histone 2", "aln": "--MPE-PSRSTPAPKKGSKKAITKAQ----KKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP0-1", "uniprot_id": "H2B3B_MOUSE", "id": "Q8CGP0-1", "name": "Histone H2B type 3-B", "aln": "--MPD-PSKSAPAPKKGSKKAVTKAQ----KKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N257-1", "uniprot_id": "H2B3B_HUMAN", "id": "Q8N257-1", "name": "Histone H2B type 3-B", "aln": "--MPD-PSKSAPAPKKGSKKAVTKAQ----KKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LX92-1", "uniprot_id": "A0ABK0LX92_RAT", "id": "A0ABK0LX92-1", "name": "Histone H2B", "aln": "--MPD-PSKSAPAPKKGSKKAVTKAQ----KKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33778-1", "uniprot_id": "H2B1B_HUMAN", "id": "P33778-1", "name": "Histone H2B type 1-B", "aln": "--MPE-PSKSAPAPKKGSKKAITKAQ----KKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC60-1", "uniprot_id": "H2B3_DANRE", "id": "Q6PC60-1", "name": "Histone H2B 3", "aln": "--MPE-PAKSAPAPKKGSKKAVTKTQ----KKGDKKRRKTRKESYAIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BJA5-1", "uniprot_id": "H2B1_DANRE", "id": "Q5BJA5-1", "name": "Histone H2B 1/2", "aln": "--MPE-PAK--AAPKKGSKKAVTKTA----GKGGKKRKRTRKESYAIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1R4A4-1", "uniprot_id": "F1R4A4_DANRE", "id": "F1R4A4-1", "name": "Histone H2B", "aln": "--MPE-PAK--TAPKKGSKKAVTKTA----GKSGKKRRRTRKESYAIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A860-1", "uniprot_id": "A0AB13A860_DANRE", "id": "A0AB13A860-1", "name": "Histone H2B", "aln": "--MPE-PAK--PAPKKGSKKAVSKTA----GKGGKKRKRTRKESYAIYVYKVLKQVHPDTGISSKA--MGIMNSFVNDIFERIAGEASRLAHYNKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02283-1", "uniprot_id": "H2B_DROME", "id": "P02283-1", "name": "Histone H2B", "aln": "--MPP--KTSGKAAKKAGK--AQKNI----TKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKA--MSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A2R8Y619-1", "uniprot_id": "H2BK1_HUMAN", "id": "A0A2R8Y619-1", "name": "Histone H2B type 2-K1", "aln": "--MSA---EYGQRQQPGGRGGRSSGN----KKS-KKRCR-RKESYSMYIYKVLKQVHPDIGISAKA--MSIMNSFVNDVFEQLACEAARLAQYSGRTTLTSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02293-1", "uniprot_id": "H2B1_YEAST", "id": "P02293-1", "name": "Histone H2B.1", "aln": "--MSAKAEKKPASKAPAEKKPAAKKTST--STDGKKRSKARKETYSSYIYKVLKQTHPDTGISQKS--MSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0AB32TUN2-1", "uniprot_id": "A0AB32TUN2_DANRE", "id": "A0AB32TUN2-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * .. : : :: : :. : * ::..:. *. : ::: : . : : ..* :.:. : . : . ", "identical_positions": 4, "similar_positions": 39, "identity": "2.92%" }, { "cls_id": "homologset.agr.SGD:S000002633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C0HKE1-1", "uniprot_id": "H2A1B_MOUSE", "id": "C0HKE1-1", "name": "Histone H2A type 1-B", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP6-1", "uniprot_id": "H2A1H_MOUSE", "id": "Q8CGP6-1", "name": "Histone H2A type 1-H", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAK----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04908-1", "uniprot_id": "H2A1B_HUMAN", "id": "P04908-1", "name": "Histone H2A type 1-B/E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C0HKE5-1", "uniprot_id": "H2A1G_MOUSE", "id": "C0HKE5-1", "name": "Histone H2A type 1-G", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE6-1", "uniprot_id": "H2A1I_MOUSE", "id": "C0HKE6-1", "name": "Histone H2A type 1-I", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE2-1", "uniprot_id": "H2A1C_MOUSE", "id": "C0HKE2-1", "name": "Histone H2A type 1-C", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE4-1", "uniprot_id": "H2A1E_MOUSE", "id": "C0HKE4-1", "name": "Histone H2A type 1-E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVK7-1", "uniprot_id": "D3ZVK7_RAT", "id": "D3ZVK7-1", "name": "Histone H2A", "aln": "--------MTG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ARS7-1", "uniprot_id": "A0A8I6ARS7_RAT", "id": "A0A8I6ARS7-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGSYSERVGAGAPVYLAAVMEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------YHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKE3-1", "uniprot_id": "H2A1D_MOUSE", "id": "C0HKE3-1", "name": "Histone H2A type 1-D", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE8-1", "uniprot_id": "H2A1O_MOUSE", "id": "C0HKE8-1", "name": "Histone H2A type 1-O", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE7-1", "uniprot_id": "H2A1N_MOUSE", "id": "C0HKE7-1", "name": "Histone H2A type 1-N", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE9-1", "uniprot_id": "H2A1P_MOUSE", "id": "C0HKE9-1", "name": "Histone H2A type 1-P", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP7-1", "uniprot_id": "H2A1K_MOUSE", "id": "Q8CGP7-1", "name": "Histone H2A type 1-K", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTET------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RDM4-1", "uniprot_id": "M0RDM4_RAT", "id": "M0RDM4-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGSKARAKAKTRSFRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKVK----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGP5-1", "uniprot_id": "H2A1F_MOUSE", "id": "Q8CGP5-1", "name": "Histone H2A type 1-F", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKPKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20671-1", "uniprot_id": "H2A1D_HUMAN", "id": "P20671-1", "name": "Histone H2A type 1-D", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BFU2-1", "uniprot_id": "H2A3_MOUSE", "id": "Q8BFU2-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L7L0-1", "uniprot_id": "H2A3_HUMAN", "id": "Q7L7L0-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4FZT6-1", "uniprot_id": "H2A3_RAT", "id": "Q4FZT6-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C170-1", "uniprot_id": "H2A1E_RAT", "id": "P0C170-1", "name": "Histone H2A type 1-E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93077-1", "uniprot_id": "H2A1C_HUMAN", "id": "Q93077-1", "name": "Histone H2A type 1-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GSS7-1", "uniprot_id": "H2A2A_MOUSE", "id": "Q6GSS7-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FI13-1", "uniprot_id": "H2A2A_HUMAN", "id": "Q6FI13-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CC09-1", "uniprot_id": "H2A2A_RAT", "id": "P0CC09-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C0S8-1", "uniprot_id": "H2A1_HUMAN", "id": "P0C0S8-1", "name": "Histone H2A type 1", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAKGK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54CQH7-1", "uniprot_id": "A0AA54CQH7_DANRE", "id": "A0AA54CQH7-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAESYAIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK-------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99878-1", "uniprot_id": "H2A1J_HUMAN", "id": "Q99878-1", "name": "Histone H2A type 1-J", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKTK----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96KK5-1", "uniprot_id": "H2A1H_HUMAN", "id": "Q96KK5-1", "name": "Histone H2A type 1-H", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTES------------------------------------------------HHKAK----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IZ20-1", "uniprot_id": "A0AC58IZ20_DANRE", "id": "A0AC58IZ20-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA52P314-1", "uniprot_id": "A0AA52P314_DANRE", "id": "A0AA52P314-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGKYKLKI--------------------------------NMSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AWT1-1", "uniprot_id": "A0A8M3AWT1_DANRE", "id": "A0A8M3AWT1-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGKXTAAIXLET----------------------------KMSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F5W3-1", "uniprot_id": "E7F5W3_DANRE", "id": "E7F5W3-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKATKGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZUY3-1", "uniprot_id": "H2AX_DANRE", "id": "Q7ZUY3-1", "name": "Histone H2AX", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGQAAASS------------------------------------------GKSGKKGSSQSQ----------------------------------------EY----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q16777-1", "uniprot_id": "H2A2C_HUMAN", "id": "Q16777-1", "name": "Histone H2A type 2-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESH-------------------------------------------------KAKSK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BTM1-1", "uniprot_id": "H2AJ_HUMAN", "id": "Q9BTM1-1", "name": "Histone H2A.J", "aln": "--------MSG-RGKQGGKVRAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESQ-------------------------------------------------KTKSK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96QV6-1", "uniprot_id": "H2A1A_HUMAN", "id": "Q96QV6-1", "name": "Histone H2A type 1-A", "aln": "--------MSG-RGKQGGKARAKSKSRSSRAGLQFPVG-RIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTR-IIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHH-----------------------------------------------HKAQSK--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27661-1", "uniprot_id": "H2AX_MOUSE", "id": "P27661-1", "name": "Histone H2AX", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSATVG--------------------------------------------PKAPAVGKKASQASQEY-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LP96-1", "uniprot_id": "A0ABK0LP96_RAT", "id": "A0ABK0LP96-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVG--------------------------------------------PKAPAGGKKASQPSPTSTKALLRATTSLTERAEPLRAPARRVPIPFSPLSPRVFTLPCAASGSATGRGRRGTYPSRSS----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16104-1", "uniprot_id": "H2AX_HUMAN", "id": "P16104-1", "name": "Histone H2AX", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVG--------------------------------------------PKAPSGGKKATQASQEY-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84051-1", "uniprot_id": "H2A_DROME", "id": "P84051-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSNRAGLQFPVG-RIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEK--------------------------------------------------KA-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB57-1", "uniprot_id": "Q4AB57_DROME", "id": "Q4AB57-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSDRAGLQFPVG-RIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEK--------------------------------------------------KA-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04911-1", "uniprot_id": "H2A1_YEAST", "id": "P04911-1", "name": "Histone H2A.1", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG-RVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTR-IIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAK------------------------------------------------ATKASQEL-------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M0R7B4-1", "uniprot_id": "M0R7B4_RAT", "id": "M0R7B4-1", "name": "", "aln": "MSETAPAAPAAPAPVEKTPVKKKAKKTSSAAGKRKASGPPVSELITKAVAASKERSG--VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKASSGEAKPKAKKVGAAKAKKPAGSAK------------------------------------------KPKKATGSATPRKTKKTPKKAKKPGATAGAKKVSKSPKKVKAAKPKKAAKSPAKAKAPKAKATKPKASKPKANKAKKAAPRKK-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::. * ** . * : .*: :. :.: :* * ::*: : *:* :: * :* : : ::.: : : :. ..: . :.* . *: : .* . ", "identical_positions": 15, "similar_positions": 45, "identity": "4.92%" }, { "cls_id": "homologset.agr.SGD:S000002634", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTP6-1", "uniprot_id": "KAD2_MOUSE", "id": "Q9WTP6-1", "name": "Adenylate kinase 2, mitochondrial", "aln": "MAPNVLA-SEPE--IPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLET-PSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKATCKDLVMFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54819-1", "uniprot_id": "KAD2_HUMAN", "id": "P54819-1", "name": "Adenylate kinase 2, mitochondrial", "aln": "MAPSVPA-AEPE--YPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLET-PLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29410-1", "uniprot_id": "KAD2_RAT", "id": "P29410-1", "name": "Adenylate kinase 2, mitochondrial", "aln": "MAPNALA-PEPE--HPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLET-PSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1L8L9-1", "uniprot_id": "KAD2_DANRE", "id": "Q1L8L9-1", "name": "Adenylate kinase 2, mitochondrial", "aln": "MAPSTQE-DDTVSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDT-PACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAATCKDLVYFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U915-1", "uniprot_id": "KAD2_DROME", "id": "Q9U915-1", "name": "Adenylate kinase 2", "aln": "MAPNAAVPVERYEPENIGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVVDMIDSNLDK-PECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQRKRPAQIQL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07170-1", "uniprot_id": "KAD2_YEAST", "id": "P07170-1", "name": "Adenylate kinase", "aln": "MSS------------SESIRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVSDDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDELLVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQTEPIVDFYKKTGIWAGVDASQPPATVWADILNKLGKD---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. .*. :*:****:******* * *.: ..**:******: ::.*::** . * ** * ****:::*::*..:* . * *****:*******: *** ** ::.:: *: .**: : *.**: ** ***** ******: * ***: *.**:***.*::***** :*: ** :** ** *::::* *: :**:: . *:: * : ", "identical_positions": 105, "similar_positions": 63, "identity": "43.21%" }, { "cls_id": "homologset.agr.SGD:S000002636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY40-1", "uniprot_id": "D3ZY40_RAT", "id": "D3ZY40-1", "name": "Pre-mRNA cleavage complex 2 protein Pcf11", "aln": "MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDEN-------TRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPN--------VNTSSIHVNPKFLNKSPDEPSTPGTVVSSPNISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETANLGPGSAPSKLHVPQIPTMAVKTPHQVPVQPDKSRVGPSLQMQDLKGTNRDPRLNRMSQHSSHGKEQSHRKEFVMNTINQSDIKTSKTVPSEKLNSSKQEKSKSGERITKKELDQLDSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKAEGKDEDVKEKRKTAEKKDKDEHMKSSEHRLIGSRSKIINGVVQKQDMVTEELEKQGTKPGRSSTRKRSRSRSPKSRSPIVHSPKRRDRRSPKRRQRSMSPTLAPKAGKMRQSGLKQSHMDEFPPPSREERNIKRSAKQDVRDPRRLKKMDEDRPQETAGQHSMKSGGDPKENIENWQSSKSAKRWKSGWEENKSLQQGDEHSKPPHLRHRESWSSTKGILSPRAPKQQ-HRLSVDANLQIPKELTLASKRELLQKTSERLASGEITQDEFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYEDSDKPFVDGPASRFAGLDTNQRLTALAEDRPLFDGPGRPSVTRDGPTKMIFEGPNKLSPRIDGPPTPGSLRFDGSPGQIGGGGPMRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFE--GPIGQGGGGGFRFEGSPSLRFEGSAGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGSLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGG--IRFEGPLLQQGVGMRFEGPHGQSVAGLRFEG-HNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGP-VPGGGLRIEGPLGQGGPRFEGCHSLRFDGQPGQPSLLPRFDGLHGQPGPRFERT-GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRIES--FNQTGPYSDPPGNAFNVPSQGLQFQRHEQIFDTPQGPNFNGPHGPGNQN-FPNPINRPSGHYFDEKNLQSSQFGNFGNLPTPMSVGNIQTSQQVLTGVAQPVAFGQGQQFLPVHPQNPGAFIQNPSGGLPKAY--PDNHLSQVDVNELFSKLLKTGILKLSQPDSATAQVNEAVAQPPPEEEEDQNEDQDVPDLTNFTI---------------EELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVTHRRWYYSLTDWIEFEEIADLEERAKSQFFEKVH----EEVVLKTQEAAKEKEFQSVPAGPAGAVESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKVTFSSLYG---ITSSFDCTPSPSK-----TPVENPLNIMLNIVKNELQEPCENPKVKEEQIDAPPACSEESVATPTEIKTESDTVESV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9Z4-1", "uniprot_id": "PCF11_MOUSE", "id": "G3X9Z4-1", "name": "Pre-mRNA cleavage complex 2 protein Pcf11", "aln": "MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDEN-------TRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPN--------VNTSSIHVNPKFLNKSPDEPSTPGTVVSSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETANLGPGSVPSKLHVPQIPTMAVKTPHQVPVQPDKSRAGPSLQMQDLKGTNRDPRLNRMSQHSSHGKEQSHRKEFVMNTINQSDIKTSKNVPSEKLNSSKQEKSKSGERITKKELDQLDSKSKSKSKSPSPLKNKLSHTKDLKNQDSESMRLSDMSKRDPRLKKHLQDKAEGKDEDVKEKRKTAEKKEKDEHMKSSEHRVIGSRSKIINGIVQKQDMVTEELEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPNLAPKAGKMRQSGLKQSHMEEFPPPSREERNIKRSAKQDVRDPRRLKKMDEDRPQETAGQHSMKSGGDPKENIENWQSSKSAKRWKSGWEENKSLQQGDEHSKPPHLRHRESWSSTKGILSPRAPKQQ-HRLSVDANLQIPKELTLASKRELLQKTSERLASGEITQDEFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYEDSDKPFVDGPASRFAGLDTNQRLTALAEDRPLFDGPGRPSVTRDGPAKMIFEGPNKLSPRIDGPPTPGSLRFDGSPGQMGGGGPMRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFE--GPIGQGGGGGFRFEGSPSLRFEGSTGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGSLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEG-HNQLGGNLRFEGPHGQPGVGIRFEGPIVQQGGGMRFEGP-VPGGGLRIEGPLGQGGPRFEGCHSLRFDGQPGQPSLLPRFDGLHGQPGPRFERT-GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRIES--FNHSGPYNDPPGNTFNVPSQGLQFQRHEQIFDTPQGPNFNGPHGPGNQN-FPNPINRASGHYFDEKNLQSSQFGNFGNLPTPISVGNIQASQQVLTGVAQPVAFGQGQQFLPVHPQNPGAFIQNPSGGLPKAY--PDNHLSQVDVNELFSKLLKTGILKLSQPDSATAQVTEAVAQPPPEEDEDQNEDQDVPDLTNFTI---------------EELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVTHRRWYYSLTDWIEFEEIADLEERAKSQFFEKVH----EEVVLKTQEAAKEKEFQSVPAGPAGAVESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSK-----TPVENPLNIMLNIVKNELQEPCESPKVKEEQIDAPPACSEESVATPTEIKTESDTVESV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94913-1", "uniprot_id": "PCF11_HUMAN", "id": "O94913-1", "name": "Pre-mRNA cleavage complex 2 protein Pcf11", "aln": "MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDEN-------TRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPN--------VNTSSIHVNPKFLNKSPEEPSTPGTVVSSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLNRISQHS-HGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQLDSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVKEKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSREDRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWKSGWEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQHRLSVDANLQIPKELTLASKRELLQKTSERLASGEITQDDFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFE--GPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGG--IRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQS-FSNPLNRASGHYFDEKNLQSSQFGNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQGQQFLPVHPQNPG-FVQNPSGALPKAY--PDNHLSQVDVNELFSKLLKTGILKLSQTDSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTNFTV---------------EELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVTHRRWYYSLTDWIEFEEIADLEERAKSQFFEKVH----EEVVLKTQEAAKEKEFQSVPAGPAGAVESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSK-----TPVENPLNIMLNIVKNELQEPCDSPKVKEERIDTPPACTEESIATPSEIKTENDTVESV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39081-1", "uniprot_id": "PCF11_YEAST", "id": "P39081-1", "name": "Protein PCF11", "aln": "----------MDHDTEVIVKDFNSILEELTFNSRPIITTLTKLAEENISCAQYFVDAIESRIEKCMPKQKLYAFYALDSICKNVGSPYTIYFSRNLFNLYKRTYLLVDNT-------TRTKLINMFKLW------------------------------------------------------------------LNPNDTGLPLFEGSALEKIEQFLIKASALHQKN--------------------------------------LQAMLPTPTVPLLLRDIDKLTCLTSER-----------LKNQPNDEKLKMKLLVLSQLKQELKREKLTLNALKQVQMQLRQVFS--------QDQQVLQERMRYHELQQQQQQQQQQQQQQQQQQQQYHETKDMVG-----------------------SYTQNSNSAIPLFGNNSDTTNQQNSLSSS---LFGN----ISGVESFQEIEKK----------KSLNKINNLYASLKAEGLIYTPPKE------------------------------------------------------------------------------------------------------------------------------------------------SIVTLYKKLNGHSNYSLDSHEKQLMKNLPKIP--------------------------------LLNDILSDCKAYFATVNIDVLNNPSLQLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQTLLQE----------------------------------------------NPIVQNN------------------------------LIHLLYRSKPNK---------------------------------------------------------------CSVCGKRFGNSESEKLLQN----------------------EHLDWHFRINTRIKGSQNTANTGISN-----------------------------SNLNTTTTRKNIQSRNWYLS----------------------------------------DSQWAAFKDDEITSTKHKN--------DYTDPHANKNIDKSALNIHADENDEG----------------------------------------------------------------------------------------SVDNTLGSDRSNELEIRGKYVVVPETS----QDMAFK-----------------------CPICKETVTGVYDEESGEWVWKNTIEVNGKYFHSTCYH---ETSQNSSKSNSGK-----VGLDDLKKLVTK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z9W4-1", "uniprot_id": "A1Z9W4_DROME", "id": "A1Z9W4-1", "name": "Pre-mRNA cleavage complex 2 protein Pcf11", "aln": "---MEQLFQNYRDDERRIGEEYLSSLQDLNCNSKPLINMLTMLAEENINYAHIIVKVVEYYISQVAPEFKLPILYLIDSIVKNVKSSYVQLFGQCIVNIFLHAFESVQHSQSQVLEKVRERMYALRQTWNEVFPPSKMYALDVKVKRLDNNWPITAKQPTNKIHVNPAIHVNPDFLKPGLVPGMPGNPTITSDMEEILQAKTRELLELKKRKLELELEQTKKHLEEQERQLTQTTDAMVGAPIIMPAPTPAAICPPITDPGIAVHNQRAPGVMGNVGPVMHNMPVAPQLFANKPKVHPVNPALLNSVRQRDPRLARQMHAASSHPAAPARNDPRLEAKSSSSQKSSRSRSKSPVRNSSSRSGKSGSSSHSSSSSRKRSESKSSTTSSSSSSSDVRHKGVTASSSNQ-----------PTVKRSGKITSKDSDRYVRNGSPLGSAKRKSSSPSSSPSKSKRSTSHKSSSSRGKTSSLRSRSRSPVFMDVDLRTGVRSKSPESRAVAPSSLPLAGASLPASAKAPKDLEKPTFQILEPGHPPAPPSPPIIDVSSMDIDLRRPKTPPPPTFDSVDSLDQKDTTSGHISSTIIQASGASNASPSGASTSKLPAKVSFKIQKQFNKLEKSTANLSTVSMLNSNPTTSGTPAASLVRQSSPSPSSSSISSQGNVSDALQLSINKLLQVQGGAGEKRPADALPPHIDGEEQPPQQKRSKSAKLDALFGSEDVDLRREILVVKPGVIVVEDDSMDECDVDKPTKKSGSPPKKATLEELRAKLANSARIQNKQGKSDKSRDQAVSQRLKQLAELKVNDDSQEAHDEKVRTILSQAQEMYENNGMNQEQYKDLVQKVVAINENSKIKESRRRDNDLERNAARDAVLRKRIPKLKGNENHSAGSPHTDGSPRYDDQPAAAPEKPSNKRDKTKREMKRRKPTKWGEQVDAGAAQRTAWQLANVNNNNNNNNNKRGGIQLPVQPQAGFRGMPWQQPPAMVLGQSAVPPPPQPPSMISMPPVPPVTMTKAINSLDNPMADVVRSITIDGGSKEIRFYNQVAIIFMDGDQPHEIGFQPGQRVIFIDHNEPLPLCFNDDYKPFHLDGQLHRIRFGFPSRELYIDEHWYEIYFGGPAVSVPIGNKLHIIKAEGPPPNVDIGRVRRDLVVGKINMIADAHTIVPLFLDARQQTFQLGAEQHSLQFVDSFQYALLDGQLQKMEYGGLPKGMMLNGGRSCFIRFGTLPKGVIAGKTHVADMVYIKTDAPAEPPKPPPIIVKPPPVVEQPKPAPVAVAPISLPAAAAALESLNINDLFQKLVSSGIIGGATAAPTLPAADSSAAKEPTASATEPSTASATVAPATLPAGPPAEPIKRIDLRKPESIKTRQAAVVAVLYLGMQCSSCGVRFPPEQTIKYSQHLDWHFRQNRRERDSTRKATSRKWYYDLNDWRQYEEIEDVEEREKNFLEAQGQPGGVEALDELSQQRSLDSPVPTCAAGRDDVDHCCDMCHEKFEQFYNEELEEWHLRSAIRVEDKIYHPLCYEDYKASLNPPTEVKSDQDVDMNNTDDNAMDTLIKVEDDEDEGTPNSSQPIFEDDDDDVIVLPNEEPSVTEIVDDDDEDEYVPGNVTRADMGNESQDKTESNSETKEPKKDQVELGEQQQNESANESDVEIQEPNIPFTDLDTYVEKEMDEATRAALLNVKIKEEPKDEYEEDEDDGFEDVGTVVSLLPLPEDEISIHSSETQTHTIGSSASPATIERPASVTSLSLPANEADELEQGDANTDTDAELNGEKQEATHNLSAVGPALPLASIVNKIKINITKNTSSNSHNSASNTTTTDSQVSAISVIGGSGAAGGASGAGDPVQQVNAIQTISTIPVLCGGNTFVPKIATSTPSNVISSISVIGSTYGASSSSNGSRSTTSTASSAPAASLLAETGSLKSPTPPLATVDPDPEPVVEQKPALRNATLKRTKKVQNGIETSGLCSIM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:: * *::*. **:* *. ** *****: *: :*. :* : .. ** :* :*** *** * * : :. : .: *:.. .* : : . * . . :. : : . * ::: : : : . : .:: . .* :* *:. ::: .. . : : . . . . . .: .:.:.. . . ... .. . :...: : .. . :.. .** . .. . . . .. . :: . . :: : : . * :. : : : . :.. . * : ::: :*.: : . : : :: :. : . ..: : : : .. ::: .. .. : . . . : . : . .: : :. ::* * * . : : : * :*:* . ::** ** :.:*.*:.* .. * : . ...: :: . : : ", "identical_positions": 54, "similar_positions": 200, "identity": "2.75%" }, { "cls_id": "homologset.agr.SGD:S000002639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSY5-1", "uniprot_id": "A0A8I5ZSY5_RAT", "id": "A0A8I5ZSY5-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAASSEPHEPE----KKPVKLLGILDIENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGYWFHCRYNFAKQRIQERIAREGIKDQ---------------HFIR-KHP-PQS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7J4-1", "uniprot_id": "COX20_MOUSE", "id": "Q9D7J4-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAAAPEPHETE----KKPFKLLGILDVENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNK---------------ILYESTHLDPERKMKTNNSS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RI15-1", "uniprot_id": "COX20_HUMAN", "id": "Q5RI15-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAAPPEPGEPEE---RKSLKLLGFLDVENTPCARHSILYGSLGSVVAGFGHFLFTSRIRRSCDVGVGGFILVTLGCWFHCRYNYAKQRIQERIAREEIKKK---------------ILYEGTHLDPERKHNGSSSN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH88-1", "uniprot_id": "COX20_DANRE", "id": "Q6DH88-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MTE--EDGKTQ------GMKVLGILDIHNTPCAREAILHGAAGSVAAGLLHFLATSRVKRSFDVGVAGFMITTLGSWFYCRYNNAKLRFQQRIIQEGLKNK---------------VFYEGTDLDPTLKKTGDK----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG00-1", "uniprot_id": "Q9VG00_DROME", "id": "Q9VG00-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAEEPEEPAKS-------FVIFG-RDVAQIPCFRNSFLYGISGGIGIGLLTFLGTSRTHLSTHVGFGSFFCGTIAYWMTCRYQWSVRRFEQQQLREAMRRQ---------------ALYEGTQRERDLDLKSA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04935-1", "uniprot_id": "COX20_YEAST", "id": "Q04935-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "MRWWPWSNQTEDQKQQQQPQGKADGDRVLTNYSRGQKILLEDTPPKFADDLSNSQLAKKQERATLKEAWDSIRWSDFSLQKLTSIPCFRDAGMLGFSSMFLMGSIIFIYHKSPTKATNWAMSSLILGSIVGWEQCRLKRQKSFQIAQLAKETVAKKEKPMLHNVPHDPSLPGQWEAAKNEKQSQFEQSNQNLSQASSEKKWYKFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . :. .: . ** *.: : * . . * *: . : . ....:: :: * ** : : :* : : . . ", "identical_positions": 11, "similar_positions": 32, "identity": "5.37%" }, { "cls_id": "homologset.agr.SGD:S000002640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13195-1", "uniprot_id": "HEM1_RAT", "id": "P13195-1", "name": "5-aminolevulinate synthase, non-specific, mitochondrial", "aln": "---METVVRRCPFLSRVPQAFLQKAGKS--LLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGS--SVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGASGGGIGDR----------------------DGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSNEGRALRRQHQRNVKLMRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFLEKLLLTWKRVGLE-------LKP-HSSAECNFCRRP--LHFEVMSEREKAYFSGMS-KMVSAQA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC19-1", "uniprot_id": "HEM1_MOUSE", "id": "Q8VC19-1", "name": "5-aminolevulinate synthase, non-specific, mitochondrial", "aln": "---METVVRRCPFLSRVPQAFLQKAGKS--LLFYAQNCPKMMEVGAKPAPRTLSTSAVHCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPSGHPSPATSQGSGSKCPFLAAQLSQTGS--SVFRKASLELQEDVQEMHAVRKEAAQSPVPPSLVNVKTDGEDPSRLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMETVKQHGAGAGGTRNISGTSKFHVELEQALADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDR----------------------DGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSSEGRALRRQHQRNVKLLRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFVEKLLVTWKRVGLE-------LKP-HSSAECNFCRRP--LHFEVMSEREKAYFSGMS-KMVSAQA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13196-1", "uniprot_id": "HEM1_HUMAN", "id": "P13196-1", "name": "5-aminolevulinate synthase, non-specific, mitochondrial", "aln": "---MESVVRRCPFLSRVPQAFLQKAGKS--LLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQ--QSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS--SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDR----------------------DGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE-------LKP-HSSAECNFCRRP--LHFEVMSEREKSYFSGLS-KLVSAQA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08680-1", "uniprot_id": "HEM0_MOUSE", "id": "P08680-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVAAAMLLRSCPVLSQGPTGLLGKVAKTYQFLFSIGRCPILATQ---------------------------------------------GPTCSQIHLKATKAGGDSPSWAKSHCPFMLSELQDRKS-KI-VQRAAPEVQEDVKTFKTDLLSTMDSTTR-------------SHSFPSFQEPE--QTEGAVPHLIQNNMTG-SQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMASKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGER----------------------DGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLP-------LQD-VSVAACNFCHRP--VHFELMSEWERSYFGNMGPQYVTTYA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63147-1", "uniprot_id": "HEM0_RAT", "id": "Q63147-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVAAAMLLRSCPVLSKGPTGLLGKVAKTYQFLFGIGRCPILATQ---------------------------------------------GPTCSQIHLKATKAGADSPSWTKSHCPFMLSELQDRKS-KI-VQRAAPEVQEDVKTFKTDLLSFMESTTR-------------SQSVPRFQDPE--QTGGAPPLLIQNNMTG-SQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHHKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGTRGAGIGER----------------------DGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLAKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLP-------LQD-VSVAACNFCRRP--VHFELMSEWERSYFGNMGPQYVTTYA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22557-1", "uniprot_id": "HEM0_HUMAN", "id": "P22557-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQ---------------------------------------------GPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKS-KI-VQKAAPEVQEDVKAFKTDLPSSLVSVSL-------------RKPFSGPQEQE--QISGKVTHLIQNNMPG-NYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGER----------------------DGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLP-------LQD-VSVAACNFCRRP--VHFELMSEWERSYFGNMGPQYVTTYA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YHT4-1", "uniprot_id": "HEM0_DANRE", "id": "Q9YHT4-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "---MSAFLHHCPFLKSSPGPSARKVAT---YLNLADRCPIIVRQISAKA----------------------------------------AQSSEQNGLLPHKEPKRQLATTATQVAVSMSQSCPFVSSKIGLVKASPQVQEDVQP---NLENQDTSGLI-------------SSLFSGLQSHQ--STG--PTHLLQDNFN--RPTFSYDEFFTQKIVEKKKDHTYRIFKTVNRFAEVFPFAEDYSIAGRLGSQVSVWCSNDYLGMSRHPRVVKAIGDALKKHGAGAGGTRNISGTSNYHVALENELARLHQKDGALVFSSCFVANDSTLFTLAKMLPGCEIYSDMGNHASMIQGIRNSGAKRFIFRHNDASHLEELLSRSDPLTPKIVAFETVHSMDGAICPLEELCDVAHKYGALTFVDEVHAVGLYGAHGAGVGER----------------------DNVMHKIDIVSGTLGKAFGCVGGYIASTAALVDTVRSFAAGFIFTTSLPPMVLAGALESVRVLKSDEGQALRRAHQRNVKHMRQLLLDAGLPVVNCPSHIIPIRVGNAAKNSEVCDILLEKHNIYVQAINYPTVPRGEELLRLAPSPFHNPIMMNYFAEKLLDVWQEVGLP-------LNG-PAQASCTFCDRP--LHFDLMSEWEKSYFGNMEPRYITVAAQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18680-1", "uniprot_id": "O18680_DROME", "id": "O18680-1", "name": "5-aminolevulinate synthase", "aln": "--------MQCPFLNRFTASFIRNYAET-LCQSYGSHCPVVGKT----------------------------------------------LVSGEKKLSLVAASVTRSHSTGANAHANAGGPATANA------TAPVSAPASADPGKASAKET----------------------------------------------------FPYERFFNEQIMKKKRDHSYRVFKKVNRLAGDGLFPHALEYSERTEKPITVWCSNDYLGMSAHPGVKRAVQDALNRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFTLAKLLPGCEIFSDAGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHAVGLYGDHGAGVGER----------------------DGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLPPTVLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHIIPIKIGDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDLS-------TNVPLSPNACMFCNSESCWHQDTSPDLECG-IPNCPRLEISLAA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09950-1", "uniprot_id": "HEM1_YEAST", "id": "P09950-1", "name": "5-aminolevulinate synthase, mitochondrial", "aln": "--------MQRSIFARFGNSSAA--------------------------------------------------------------------VSTLNRLSTTAAPHAKNGYATATGAGAAAATATASS--------THAAAAAAAAANHSTQES---------------------------------------------------GFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADK----VTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHID--LRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQLEVSSGIKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: * : . : . . . * *: :: .:: :*: *::** *:.:** * :.. : ::********.:* ** * * .::..:*.********:* . ** ** ** *:.**:*:**:****:.* *.: : . *:** ****** **::: . :.:*:*** ..*.:**. **::***:*:** *::. :*:: *::.:.**:**:********** *.*:.:: . :: ::*:::*****:** :***:*.: *:* .**:*.******:*** ::.** ::. . ** :*::. ::. : *:** ****:*: :.:. .: .: *: :. *:*:**:***.** * **::*:* *. : : : : .: : * . . * . . : . :. ", "identical_positions": 154, "similar_positions": 156, "identity": "22.35%" }, { "cls_id": "homologset.agr.SGD:S000002641", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RJR6-1", "uniprot_id": "RTN3_RAT", "id": "Q6RJR6-1", "name": "Reticulon-3", "aln": "--------------------------------------------------MAESSAATQSPSVSSSSSGAEPS-------------TLGGGGGSPGACPALGAKSCGSSCA-------------------VGLSSLCSDEPPSKIMTSSFLSSSEIYNP-----------DPTTPLG---------------SETLGSHLVAKDGKDPLVLLDKKTLDSPQGTNKDRVDTPVSLAADIPCSHPSIPDSFPEQPTFLSKETDPTEEWVVKNQEPKNPSEVPSGEDRSALDLG------------------QRKAEHICTHSLSPSEPAVASVEKDS-----------------------------PESPFEVIID-KATFDREFKDLYKESTDDLGGWAAHGDRESPADLLEMN------------DKVFP--LRNKEAGRYPSSALLGRQFSHTTAALEEVSRCVNDMHNFT---NEILTWDLDPQAKQQADKSPCTTESTGLDRSEHRSEIPVINLKTSPQQKMP-------VCSFNGSTPITRSTGDWTETFTEGKPVKGYLSSTKEAGGKGVPDSSQP--------------ISGSGAATVEVTLPDLRGTWPNSVLGEVT--EVDSSGESDDTVIEDTTENPSVKNNKVLPEKSDSLPSAAVKTSERENKETTSHETVRSEMYENSEQQQAHA-------ETPTQRSLEGQMSPQVPNMLNEVIPENLAMTDTTRVCSAAPPSVLSETGFSLTVPASAKSESLLGKNVEDTDGSSPEDLMAALTGTEEKGTVDKEKGD-VLEAVLEKIANVKNTLP----VELLHENKLSSSETKNTKSKYSEHSRETNGGAPKVSSDLEQEQLTIRAIKELG---AKQVQAER----------MSPGGKLKRTFD------------------------------------PQSGPQNSSDILEHTDITTGSDLG-IPKKPTIIKDTRIDSISSLTKTETVNKHVLARLLSDFPVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHSYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES97-1", "uniprot_id": "RTN3_MOUSE", "id": "Q9ES97-1", "name": "Reticulon-3", "aln": "--------------------------------------------------MAESSAATQSPSVSSSSSGAEPS-------------ALGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQAGLSSLCSDEPPSKSMTSSFLSSSEIHNP-----------DPTTPLGEK-------------SETLGSQFVLAKGKDPLVLLDKKKLDSPQGTNKDRVDAPVSLATGIPCSHPSIPDSFPEQPAFLSKEIGPAEEWVVKDQEPKNPNKVPDGEDRSALDFG------------------QSKAEHICTYSLSPSELPVASVEKDS-----------------------------PESPFEVIID-KATFDREFKDLYKENPNDLGGWAAHGDRESPADLLEMN------------DKLFP--LRNKEAGRYPSSVLLGRQFSHTTAALEEVSRCVNDMHNFT---NEILTWDLDPQAKQQANKTSCTTESTGLDRSELRSEIPVINLKTNPQQKMP-------VCSFNGSTPITKSTGDWTEAFTEGKPVRDYLSSTKEAGGNGVPGSSQLHSELPGSMPEK--WVSGSGAATVEVTLPNLRGAWPNSVMGEVT--EVDSSGESDDTVIEDITEKP------------DSLPSAAAKTSEREIKETPSRETVRSEMCENSEQPQAQP-------ETPTQKSLEGEVASQVPNTLNEVTPEKLDMTNNPKVCSAAPPSVLNETGFSLTVPASAKLESLLGKYVEDTDGSSPEDLMAVLTGAEEKGIVDKEEGD-VLEAVLEKIADFKNTLP----VELLHESELSGSETKNIKSKYSEDSRETTGGAPTMSPDLEQEQLTIRAIKELGERQAEKVQDEG----------ISSGGKLKQTFA------------------------------------PQSGPQSSSDILEHTDVKTGSDLG-IPKNPTIIKNTRIDSISSLTKTEMVNKNVLARLLSDFPVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JK11-1", "uniprot_id": "RTN4_RAT", "id": "Q9JK11-1", "name": "Reticulon-4", "aln": "MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPA--AAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAP---APSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEP---------AAPPSTPAAPKRRGS-GSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKED-LVCSAALHSPQESP-----VGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAAR----ANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFT-SATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEK-TSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKAL-GTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVS-ETVAQHK-EERLSASPQELGKPYLESFQPNLHSTKDAAS-NDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPK-LAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVS--DEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P72-2", "uniprot_id": "RTN4_MOUSE", "id": "Q99P72-2", "name": "Reticulon-4", "aln": "MEDIDQSSLVSSSADSPPRPPPAFKYQFVTEPEDEEDEEDEE-EEEDDEDLEELEVLERKPAAGLSAAPVPP---AAAPLLDFSSDSVPPAPRGPLPAAPPTAPERQPSWERSPAAS---APSLPPAAAVLPSKLPEDDEPPAR--PPAPAGASPLAEP---------AAPPSTPAAPKRRGS-GSVDETLFALPAASEPVIPSSAEKIMDLKEQPGNTVSSGQEDFPSVLFETAASLPSLSPLSTVSFKEHGYLGNLSAVASTEGTIEETLNEASRELPERATNPFVNRESAEFSVLEYSEMGSSFNGSPKGESAMLVENTKEEVIVRSKDKED-LVCSAALHNPQESPATLTKVVKEDGVMSPEKTMDIFNEMKMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAAR----ANMESKVDKKCFEDSLEQKGHGKDSESRNENASFPRTPELVKDGSRAYITCDSFS-SATESTAANIFPVLEDHTSENKTDEKKIEERKAQIITEK-TSPKTSNPFLVAIHDSEADYVTTDNLSKVTEAVVATMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESIYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSTGASVAQPSASPLEVPSPVSYDGIKLEPENPPPYEEAMSVALKTS-DSKEEIKEPESFNAAAQEAEAPYISIACDLIKETKLSTEPSPEFSNYSEIAKFEKSVPDHCELVDDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVS-ETVTQHKHKERLSASPQEVGKPYLESFQPNLHITKDAAS-NEIPTLTKKETISLQMEEFNTAIYSNDDLLSSKEDKMKESETFSDSSPIEIIDEFPTFVSAKDDSP----KEYTDLEVSNKSEIANVQSGANSLPCSELPCDLSFKNTYPKDEAHVS--DEFSKSRSSVSKVPLLLPNVSALESQIEMGNIVKPKVLTKEAEEKLPSDTEKEDRSLTAVLSAELNKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQAQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQC3-1", "uniprot_id": "RTN4_HUMAN", "id": "Q9NQC3-1", "name": "Reticulon-4", "aln": "MEDLDQSPLVSSS-DSPPRPQPAFKYQFVREPEDEEEEEEEE-EEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAEN-MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDS-DMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASS-VNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALGGD-------------------TGNVSGGAQDDNAHTEHYFANEQKKLDFG--------------------DAQEFVQRLAADAKDAKLDLDTKFAQKTDDFEDFLRDAG-------------------KEVKQGISGLTTDFMNAERGFSAPLAPFSETVAQAP-------------------VIPAQAPAVPDHAPAVPAPVAPAPAVPAPLPVEEDLLGSFTDQPSAPLQAFQP---------------------------------------------------------TAPSTANFYDDEEDDFLGKPTTAAPAAPVAPLTKANQDSDTESP-----SVSYTPSPAKKPIVDALKDQDNEKFISSEDLASDFKEEPRSAPTPAPAPAPILDAAPAVAPAPVAVP---VSVPVAKPQPVPVAVPVTTALITDLDDEEVVFKPTVQEAPKAPTIAAPVVEPKP---------------------------------------------------------------------EPPKPKVEPAKPKVVPVAPVESTQPQPKIASVEEIFCKYGLDAWFKPER----------LHPQVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04947-1", "uniprot_id": "RTN1_YEAST", "id": "Q04947-1", "name": "Reticulon-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASAQHSQAQQQQQQKS-----------------------------------------------------CNCDLLLWRNPVQTGKYFGGSLLALLILKKVNLITFFLKVAYTILFTTG------------------------------------------------------------------------SIEFVSKLFLGQGLITKYGPKECPNIAGFIKPHIDEALKQLP-------------VFQAHIRKTVFAQVPKHTFKTAVALFLLHKFFSWFSIWTIVFVADIFTFTLPVIYHSYKHEIDATVAQG--------VEISKQKTQEFSQMACEKTKPYLDKVESKLGPISNLVKSKTAPVSSTAGPQTASTSKLAADVPLEPESKAYTSSAQVMPEVPQHEPSTTQEFNVDELSNELKKSTKNLQNELEKNNA--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :.. : .. . . . : : : . : . : . . : . :: : *:: . : :: :: **: :: : : .: :: ** :* :: . : * : : ::: . : : : . : .. : .. .:.* : : : * : . . : .. .. * : .* ", "identical_positions": 11, "similar_positions": 80, "identity": "0.91%" }, { "cls_id": "homologset.agr.SGD:S000002643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2Z2-1", "uniprot_id": "PRP39_MOUSE", "id": "Q8K2Z2-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMEEYRNS--DNGSTG-----------------------------NSSEVAVVEHPDFSTEIMNVTEME---------------------------QSPDASPSAHASTEEN-----------------------------------EMANAVNLPVT---EAEGD--------FPPEFEKFWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIP-LSVDLWIHYINFLKETLEPGDQETNTTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGN-LREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHSGDD-------------------------------------GPPGDDLPSGIEDIS-PAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQPKKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIH-GSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGS--EEPEEKKAHTEDLSS--AQIIDGDLQANQAAYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5S9-1", "uniprot_id": "D4A5S9_RAT", "id": "D4A5S9-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMDEYRNS--DNGSTG-----------------------------NSSEV-VIEHPDFSTEIMNVTEME---------------------------QSPDASPSVRVSTEEN-----------------------------------EMANAVDLPVT---ETEGN--------FPPEFEKFWKTVETNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFIHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIP-LSVDLWIHYINFLKETLDPGDPETNSTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGN-LREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHNGDD-------------------------------------GPPGDDLPSGIEDITDPAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQLK-NWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIRNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIH-GSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGS--EEPEEKKAHTEDVSS--AQIIDGDLQANQAAYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86UA1-1", "uniprot_id": "PRP39_HUMAN", "id": "Q86UA1-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMDEYRNS--SNGSTG-----------------------------NSSEVVVEHPTDFSTEIMNVTEME---------------------------QSPDDSPNVNASTEET-----------------------------------EMASAVDLPVTLT-ETEAN--------FPPEYEKFWKTVENNPQDFTGWVYLLQYVEQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIP-LSVDLWIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGN-LREVTAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHSGDD-------------------------------------GPPGDDLPSGIEDITDPAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQLK-NWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEMEYSGDLKQNEENILNCFDKAVH-GSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDSLKRKAENGS--EEPEEKKAHTEDTTSSSTQMIDGDLQANQAVYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPZ7-1", "uniprot_id": "PRP39_DANRE", "id": "Q1JPZ7-1", "name": "Pre-mRNA-processing factor 39", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDSGESMTGMLDSKSPESGDSPAMEGTTGTDDVT----------------------GLSTSDLTTEQPPESQEQTQPVSDMEFSVEHL-----------------KTAVQNIDQSASPAEPAAENSEQPPESNGQQEDQSEQPDDVKEAGQGDSESPSNMELEDAPKEPAEP--AAEADPAAPQEPELPTEYERLSKVVEDNPEDFNGWVYLLQYVEQENHLLGSRKAFDAFFLHYPYCYGYWKKYADIERKHGYIQMADEVYRRGLQAIP-LSVDLWLHYITFLRENQDTSDGEAESRIRASYEHAVLACGTDFRSDRLWEAYIAWETEQGK-LANVTAIYDRLLCIPTQLYSQHFQKFKDHVQSNNPKHFLSEEEFVSLRVELAN---------ANKPSGDEDAET---------------------------------EAPGEELPPGTEDLPDPAKRVTEIEN--------------------------MRHKVIETRQEMFNHNEHEVSKRWAFEEGIKRP--YFHVKALEKTQLN-NWREYLDFELENGTPERVVVLFERCLIACALYEEFWIKYAKYLESYS-----TEAVRHIYKKACTVHLPKKPNVHLLWAAFEEQQGSIDEARSILKAVEVSVPGLAMVRLRRVSLERRHGNMEEAEALLQDAITNGRNSSESSFYSVKLARQLVKVQKSIGRAKKVLLEAVEKDETNPKLYLNLLELEYSGDVQQNEAEIIACFDRALS-SSMALESRITFSQRKVDFLEDFGSDINTLMAAYEQHQRLLAEQESFKRKAENGS--EEPDAKRQRTDDQSVASGQMMD--MQANHAGYNYNNWYQYNSW------------------GSQNSWGQY---------GQYGQYNQYYPPPPT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRW8-1", "uniprot_id": "PRP39_DROME", "id": "Q7KRW8-1", "name": "Pre-mRNA-processing factor 39", "aln": "MASEGENVVMESPGRRTRSGRKAASPAASLPTRSTRRTSKRNVQLSDHEEEAEEQVVMVQEEEEPFRGTNTAEAPALEPQFEETQHQIEDDVEMLPAEAAGVDEKSSSFPFGTVAELHSETSDDIKETRGQAGVDTLLASLAGDNANSLPSVGGNDESDNVKKADFEYNVDSLQPQMEKMNSSEDSSSQHAIAEDLADADTSNATIVNTEIVSEDELPLPSKPEINDAEEVSDEELPAPQRAELPEDAEVISEDELPASNNNNTATEPKAPLKRKAENESVKSTEDKDASSHESSTKDKSSEQYNPGSPTSESNDAQPSEKKLKVEESEPKEKKKEKERDKDKEKDKDKDNNKDKEKERKKLPDLDKYWRAVKEDSTDFTGWTYLLQYVDNESDAEAAREAYDTFLSHYPYCYGYWRKYADYEKRKGIKANCYKVFERGLEAIP-LSVDLWIHYLMHVKSN----HGDDETFVRSQYERAVKACGLEFRSDKLWDAYIRWENESKR-YHRVVQIYDRLLAIPTQGYNGHFDNFQDLINQHDVTITLANEEVIRLRKDFHERQQSKSSKSSSKHRRDSSSSSKDKDSKEREREKDKDKDKDKDKEKRETVGGGVGKSPKDTSETQVDESDSTTDLTTESESSHAASKPAMQIDFSDLSTLNDEEVVSIRDRAISARRKVHKLTVSAVTARWSFEEGIKRP--YFHVKPLERAQLK-NWKDYLDFEIEKGDRERVLVLFERCLIACALYDEFWLKMLRYLESLEDQSGVVDLVRDVYRRACRIHHPDKPSLHLMWAAFEECQMNFDDAAEILQRIDQRCPNLLQLSYRRINVERRRGALDKCRELYKHYIESTKNKGIAGSLAIKYARFLNKICHDLDAGLAALQQALERDPANTRVALQMIDLCLQ-RPKVDEQEVVEIMDKFMARADIEPDQKVLFAQRKVEFLEDFGSTARGLQDAQRALQQALTKAKEAQKKSDGSPSRKNSSSSKEGPVPTGSAAAAYNNGGSAAAVAGYNYGAANPYYGQQNTAAAYPSQTPQQASYDSYYNQWGYGSGGASANSGGSGYNYGQWSGYGNYY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03776-1", "uniprot_id": "PRP42_YEAST", "id": "Q03776-1", "name": "U1 small nuclear ribonucleoprotein component PRP42", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKYTALIHDENFSTLTLNVSRYP--------------------------------------------------------------------------------------------------------KSLAYWEKLLNYIVKAS-------APICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVIS-----HQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDD-----IMDLKQLSQLTS------------------------------------------------------------KDELLKKLKIDINYSGRKGPYLQD--------------------------AKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKND---LLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN----------------------------EYVLLRNLLEKIESSYSDNVENVDD------FEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIF-QKIIEFGWEYYLQNGMFWNCYCRLIYFDTSRSYLDKRQYIVR-KIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMFTEEP-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: . :: . : . : : . * ::. :: .:** .*: .:* * : . . :::.***:*: *: ** *: . .. :. : :* * * .* *..:*: *: .. . : ::* ** : :. .: : : ::. : ::. * : : . . :. :.: . :::. * ::: *. * :.* :: .* .**:: : . . : *:*.::. * *: .*:* ::: . . .:.: . . .. :::::.: : : . :. ::: . .. : . . : * . :: ... * .: :: . : .: :: : : : : * *: ::* :: : . . . .:: .. .: . : : ", "identical_positions": 43, "similar_positions": 181, "identity": "4.0%" }, { "cls_id": "homologset.agr.SGD:S000002644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FDV5-1", "uniprot_id": "F7FDV5_RAT", "id": "F7FDV5-1", "name": "Riboflavin kinase", "aln": "--------------ATEAEQAGRLGRRSVRSLRLSQFRPRDLWVLGGWRLSCRQAPVAAGVPLRRPSSCGIPGWSGPECRTHGGSVAGTERGAARVLRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADVSTGIYYGWASVGSGE-------------------------------VHKMVVSIGWNPYYKNVKKSMETHIIHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKQLDLPEHLKLKDDNFFQVSKSKIMNGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFV9-1", "uniprot_id": "RIFK_MOUSE", "id": "Q8CFV9-1", "name": "Riboflavin kinase", "aln": "----------------------------MRSL----------------PFFC---------------------------------------------RGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADVSTGIYYGWASVGSGD-------------------------------VHKMVVSIGWNPYYKNVKKSMETHIIHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKQLDLPEHLKLKDDNFFQVSKGKIMNGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969G6-1", "uniprot_id": "RIFK_HUMAN", "id": "Q969G6-1", "name": "Riboflavin kinase", "aln": "----------------------------MRHL----------------PYFC---------------------------------------------RGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGSGD-------------------------------VHKMVVSIGWNPYYKNTKKSMETHIMHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKRLELPEHLKIKEDNFFQVSKSKIMNGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76206-1", "uniprot_id": "RIFK_DROME", "id": "O76206-1", "name": "Putative riboflavin kinase", "aln": "---------------------------MLSQL----------------PLFAG---------------------------------------------GEIVRGFGRGSKELGIPTANFPLEVVKSLPESLPTGAYYGWANVDNGP-------------------------------VHKMVLSIGWNPFYNNKEKSVETHMLHDFNCDLYGQTLKICIVGYLRPERSFDSLESLIAAIRGDIEQAKAFLDEADKAKLKEAPFFT---EKLCSSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03778-1", "uniprot_id": "RIFK_YEAST", "id": "Q03778-1", "name": "Riboflavin kinase", "aln": "MFTWTIYVSLLLVLAGTFLMNRNTNTDIIDTFKREVDLPIPAQPGPPFPLVTD--------------------------------------------YCDIVCGFGRGSAELGIPTANVPINQLPKGINDLDLGVYFGFAHIKTVDGQELSVETRRDGRTVVYNYGQYLSEANDDLSVLPMVLSVGKNPFYGNDFKTMELHIIHDFKNDFYGARVKFNILGHIRPELNYTTKEALIEDINIDIRTAQTVLATPPYQVFKQQL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::* ****** :*******.* : : . .: * *:*:* : . * **:*:* **:* * *::* *::* *: *:** ::. *:*::*** .: : *:** *. **. *: * . :*: ", "identical_positions": 50, "similar_positions": 40, "identity": "18.18%" }, { "cls_id": "homologset.agr.SGD:S000002646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23514-1", "uniprot_id": "COPB_RAT", "id": "P23514-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFENLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNVTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIF7-1", "uniprot_id": "COPB_MOUSE", "id": "Q9JIF7-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53618-1", "uniprot_id": "COPB_HUMAN", "id": "P53618-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HV4-1", "uniprot_id": "COPB_DANRE", "id": "Q66HV4-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVTN-DSEPPSEVSLKTDLEKGEIKAKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGKLLQEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKESELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVHTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPTHERVLQDLVMDILRVLTTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVTEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDTNEAAAADVLEFVREAIQRFDNLRPLIIEKMLEVFHAIKTVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVENELKKEAG--EVKPE-----------------EEVTAAPAPKLVTEMGTYVTQSALSTSRPSK-----KEEDRPPLRGFLMDGDFYVAASLATTLTKVALRYVALAEDKRRQNSFVAEAMLIMATVLHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRRSLSHMLAVRLEEEKLSQKKESEKRNVTVQA--DDPISFMQLTAKNEMASKEDQFQLSLLAAMGNTQRKEATDPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPASCTDAEFRQMWAEFEWENKVTVNTNITDLNDYLLHILKSTNMKCLTPEKALSG-ICGFMAANLYARSIFGEDALANVSIEKPIHLGVDAPVNGHIRIRAKSQGMALSLGDKINLSQKRTAS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45437-1", "uniprot_id": "COPB_DROME", "id": "P45437-1", "name": "Coatomer subunit beta", "aln": "--MTSQVPCYTIINSP--DLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSS-SNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNV-EHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGSQ-ILEVIAVIQQTLGEVPMVEAEQRRLAG--DQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYS-LAPVA-----KAEKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTLS-----ERTPEAISVFTLYCREALGKMLDAQHDEDQR-MLKEKQKATAKVQP--DDPVLFAQLSNGRDNQLGENVFESSLNQALAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYET---ALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNMKCLTPEKALSG-QCGFMAANMYAKSIFGENALANLSIEKPVD-DPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41810-1", "uniprot_id": "COPB_YEAST", "id": "P41810-1", "name": "Coatomer subunit beta", "aln": "MTSLSSQPAYTLVFDPSPSMETYSSTDFQKALEKGSDEQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVPKLAEDGKLRHEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLREAELLEQMVPSVLACLEYRHAYVRKYAILAVFSIFKVSEHLLPDAKEIINSFIVAETDPICKRNAFIGLAELDRENALHYLENNIADIENLDPLLQAVFVQFIRQDANRTPALKAQYIELLMELLSTTTSDEVIFETALALTVLSANPNVLVPAVNKLIDLAVKVSDNNIKLIVLDRIQDINAN--NVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKELQTTVNNPDQDKAMQYRQLLIKTIRTVAVNFVEMAASVVSLLLDFIGDLNSVAASGIIAFIKEVIEKYPQLRANILENMVQTLDKVRSAKAYRGALWIMGEYAEGESEIQHCWKHIRNSVGEVPILQSEIKKLTQNQEHTEENE---------------VDATAKPTGPVILPDGTYATESAFDVKTSQKSVTDEERDSRPPIRRFVLSGDFYTAAILANTIIKLVLKFENVSKNKTVINALKAEALLILVSIVRVGQSSLVEKKIDEDSLERVMTSISILLDEVNPEEKKEEVKLLEVAFLDTTKSSFKRQIEIAKKNKHKRALKDSCKNIEPIDTPISFRQFAGVDSTNVQKDSIEEDLQLAMKGDAIHATSSSSI--SKLKKIVPLCGFSDPVYAEACITNNQFDVVLDVLLVNQTKETLKNLHVQFATLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYDG-AHGEDARYVILNDVHVDIMDYIKPATADDEHFRTMWNAFEWENKISVKSQLPTLHAYLRELVKGTNMGILTPSESLGEDDCRFLSCNLYAKSSFGEDALANLCIEKDSK---TNDVIGYVRIRSKGQGLALSLGDRVALIAKKTNKLALTHV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .**:: . . * .. .:: ****. : * :::* :: :*:*: * *:* *****:* ::: :**** .:****** : **:* :******:* ::*******::**.***** **:*.**** ::*:: ***::**:***: *:**:::*:: : *:**. *:* .*: : * ******: * . *::.**.** . * ::..:. :** *:*::* : .: .*: ::::*. : :**.:: * * :*:* :* .** *..: .*.. *:* :* ****:*******: :: : .:::*.:*:**** : *::** *:* :::**. *** ::* :****: .* * :::.: :*****::*::: ::.* ::**.*:.:*::*:.* *. **:.:: *::*.*::: ** *:*::::.: ::: * :*.*:**:*** . .. * ::.::**:*::: * :: : : . * . : ***.*:** . . : :.***:* :::.***: .* *: *: *:.*:: : : * : ::.:*:: :::::*:*.: .* * :*. :*: .: * * . .:: : : : : : *. * . . * *: * *:: . :: :: .* *: . :. ***:*:. * ********** : **:*:*****:****.:**:* :::*******::: * : **.* ::...***:*::.*:*****:*: . : . *:*. :*:****** **:. * .** ** ******::*::.. *: ** .::*.*** ***.::*. * *::.*:**:* ***:****:.*** . * *::***:*.**:******:: *:: ", "identical_positions": 339, "similar_positions": 341, "identity": "34.04%" }, { "cls_id": "homologset.agr.SGD:S000002650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VHW0-1", "uniprot_id": "Q9VHW0_DROME", "id": "Q9VHW0-1", "name": "Amidase domain-containing protein", "aln": "-------------MEIILRLLAFILNAFGMLVNKILDFVLP------RQKPK---FSGIRNPLLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVVEDRFEAALQDAKLADQFIE-KASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLAR--KNMKAPQDGDVVELVRAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCGATTFGVGSDISGSIRLPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFSEMLQIGPITRFARDLPLLLEIMAG--DKKHKLKMSEPVALKDMKVYYAF--GYSGFNCLTHPVVDFDIKLAITKAVTCLERGGVQSKKLDLKFLRNSLEIALVSLVDLKGLPSIVT-QRADRDPSMR---LLMVELFNSIIGHSIFTKEAMVLEVMKRFNGLMATGNMEEYRVEAQKIKS---HLNQLLGTQGVLIMPTFHTSALCFHTSLLNVTGIDNLLLFNILGLPATHVPMG-----------------------------TNQRGMPIGLQVVAAQYQDKLCLKVAAELEAVFHGWVPPVPHDT------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHV9-1", "uniprot_id": "Q9VHV9_DROME", "id": "Q9VHV9-1", "name": "Amidase domain-containing protein", "aln": "-------------MEIFLRLIVILVKVIALIVSPLLEAFVY------RPKSKRTLIPPIRSRLLTLSVQELRRRLQSRQLTSVELVRTYIERIEAVNKHLNALIESRFTAALEEATETDDLIA-SCQTAAEVEKLFEERPLLGLPVTIKESCALEGMTFAVGSLSR--KNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCLNPYDSERTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFPNSL-DPNIGHYLVEGPITRFAEDLSELLQVMAGK-ENSSKLRLNEPVQLNQIKVQYAL--AFEGINGWMHMAVDKDITGAICKATTHLKTLGLNVKKVKLPNLENSVEMALSGIAGQDLMDYLLTDENPEGSGKVR---ETVWEIVKSVRGHSKYTTNALIFELMRRTGAFMSQSKINQYMKETRELIG---EFENLLGDNGVLLFPTLNLPAPRHKWSILSLWGVDYTLMFNVLGLPVTHVPMG-----------------------------LNERGLPIGLSVIGAPNQDRLCLRVAVELERAFGGWKPPVPHDLDD----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7I6-1", "uniprot_id": "Q9I7I6_DROME", "id": "Q9I7I6-1", "name": "Amidase domain-containing protein", "aln": "MLKSIVTVIRLHLEELWLRILGYIMRRFLRSAMIVFSWFVVPYSRYTNIKVIRRKLPPIRSHLLEIPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREIDNVIA-MGINSVESMEELT--PLLGIPVTVKESIAVKGMTNQAGRVFK--TPQIAKSDAPVVEQIKRSGGIILLVSNTPELCLLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWGHKPTPYAVSFKGHHPTSD-FPKWGDFFTIAPMTRYAKDLPLLLKCMSD--PTGPKLTLDRPISVNGIRFFFMD--NDG--PSGMMRPLSRDLHAAINRVATDFN-----AKRVNIRKMKWSLDISLSAMLTMKNIETIYH--KTEEGEQPK---TVCKETVKYFFGCSDSILPSVIFGHLQNFMKIIPNSRHKHLASIIEALKT---EFKEMLGNDGVFLYPTFPNTAHQHYQIYHKLLEPMYMAIFNTLGLPVTNCMIG-----------------------------LDRRNLPMGIQVVANPGQDHLSLAVAREMERRYGGWVRPPSEDSHSSGGSSKQRG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBQ5-1", "uniprot_id": "Q9VBQ5_DROME", "id": "Q9VBQ5-1", "name": "Amidase domain-containing protein", "aln": "-------------MSFWSHVLDALLALVHILSDRLLEFVLDWYLG--EHKRVSGPPSLEQQTTITKSAVELAQQIRERRQRSYDIVKAYCERIESVNRDLNAVVDGPFPEALDQAREIDRKLD-EKEYSDE---DLRRLPFLGVPFSTKDSTAVAGRLHTLGLLAR--KSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAVNMAGCTFRTG--KEKDTMVCAGPMSRSARDLLPMMQVLVEP-SLKAKLKLDQKVDLKRLRYFYVS--SNGMAQCNPINRETERVMYKIRKHFEAVS--GKDVRHADLPYTKLTGKMWRYWMTQEPANFNLLLGNGAELNP--------FVELFKKILGQSDYSMAAIYG----LIDSVLPKEKEKLMREATAKCKK---SVQDLLGDDGVLFFHSSPRTAPFHYYPLVKFNDFAYFSLFNVLHLPATQVPMG-----------------------------LDSKGMPLGIQVVANPNNDRLCLAVAEELERTFGGWVPPFPLKN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97612-1", "uniprot_id": "FAAH1_RAT", "id": "P97612-1", "name": "Fatty-acid amide hydrolase 1", "aln": "-------MVLSEVWTTLSGVSGVCLACSLLSAAVVLRWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLN--EGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVY--GQTAVQLSLGPMARDVESLALCLKALLCE-HLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQPS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08914-1", "uniprot_id": "FAAH1_MOUSE", "id": "O08914-1", "name": "Fatty-acid amide hydrolase 1", "aln": "-------MVLSEVWTALSGLSGVCLACSLLSAAVVLRWTRSQTARGAVTRARQKQRAGLETMDKAVQRFRLQNPDLDSEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHASTLGLSLN--EGVTSESDCVVVQVLKLQGAVPFVHTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKSCVY--GQTAVQLSVGPMARDVDSLALCMKALLCE-DLFRLDSTIPPLPFREEIYRSSRPLRVGYYETDNYTMPTPAMRRAVMETKQSLEAAGHTLVPFLPNNIPYALEVLSAGGLFSDGGCSFLQNFKGDFVDPCLGDLVLVLKLPRWFKKLLSFLLKPLFPRLAAFLNSMCPRSAEKLWELQHEIEMYRQSVIAQWKAMNLDVVLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMEHYKGYFGDMWDNILKKGMKKGIGLPVAVQCVALPWQEELCLRFMREVERLMTPEKRPS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00519-1", "uniprot_id": "FAAH1_HUMAN", "id": "O00519-1", "name": "Fatty-acid amide hydrolase 1", "aln": "-------MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLN--EGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVY--GQEAVRLSVGPMARDVESLALCLRALLCE-DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAFLVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22580-1", "uniprot_id": "AMDY_YEAST", "id": "P22580-1", "name": "Probable amidase", "aln": "---MTVHSTWKEKVQLKKDQLNSKIKDEWKLNSTTITRLKNDKKN--LIKNIDDLCSSSENQITHSTIMALRQALEAKELSCHEITAAFCHRAALIHQVVNCLSEIMFSEALRLADYYDSNRP------------AILPPLYGIPISLKDQCNVEGVDTSLGYLCRTFKPKTKNEESLIVSFLRDLGAIIFVKTTVPSSMMATDTQSNTFGYTYNSINLSFSSGGSSGGEGSLIGAHGSLLGLGTDIGGSIRIPSSYQGLFGLKPTFGRVPYLRVDNSFE--GRETIPSVIGPLARDLSDLRYFMSCVINICQPWVQDVKCIPYHFDSSTSKLHDNYVVGIWYGDGVIDPPPSDIRALKTCEDLVN------KTKGMKAVKWEPSSELSRELFDLANEADVADSGNEIKNEFEISGEPLLDILKPMVLENGRPPYTVNEWWDLTKRVYNAQQLMRDYYLSFPESER------------PDVIISP--TTLMPFRPGDMLKTTLRYILLFNVLNFPSLSIPVGSVDCQIDG-------------------LMDTTSALNPEDKMIKTYWNDLIQSGEIDGFPIGLQVVSPTFNDNEVCKFASWLFSKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . * . : . :.: . * : : *:*.: *: * * . : * :: *.: : : *. : . * *. . : .******.:* .. : :*: :**.** *:*: *: * **: . .*::* .* : : . : .. . : . .: . . .. . . ::* * :* : : . : :: : . . ", "identical_positions": 36, "similar_positions": 80, "identity": "5.93%" }, { "cls_id": "homologset.agr.SGD:S000002651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z0M9-1", "uniprot_id": "D3Z0M9_MOUSE", "id": "D3Z0M9-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASP-KEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSVERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9M1-1", "uniprot_id": "G3V9M1_RAT", "id": "G3V9M1-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASP-KEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSTERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUQ8-1", "uniprot_id": "DDX23_HUMAN", "id": "Q9BUQ8-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ74-1", "uniprot_id": "Q9VJ74_DROME", "id": "Q9VJ74-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "---MVNDKKRRSRSR---ERHREDRPAVGNPRDRERERDRVRERDRQFDREKER--RQRRSRSREDRNRRRSPERQRPRDNVRERSR-ERGGGAGGGGGGGAEKKAKMDTGDAPPKPLIVDDEEQQDGK----EAKVKKEPLSLEELLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGTAMASGAPPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKEKELEAIRERYLGIIKKKRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGNVAGIDIKEQKRTQSKFYGDLLEKRRTEAEKEQEKVRLKKMKRKEDKQKWDDRHWSEKENDEMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPK--EIIDIIDKVGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLG------IRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYT-KKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLG-YNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTK-DDSALFYDLKQCVSASPVSTCPPELMNHPEAQHKPGTVVTKKRREEKIFA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23394-1", "uniprot_id": "PRP28_YEAST", "id": "P23394-1", "name": "Pre-mRNA-splicing ATP-dependent RNA helicase PRP28", "aln": "--------------------------------------------------------------------------MARPID------------------------VSQLIAGINKKK--------------------------GLDENTSGKIS------KPRFLNKQERS------KQERLKENEESLTP-----------------------------------------------------TQSDSAKVEIKKVNSRDDSFFNETN------DKKRNPSKQNGSKFHFSWNESEDTLSGYDPIVSTR-AIDLLWKG---------------------------------------KTPKNAAESSYMGKHWTEKSLHEMNERDWRILKEDYAIVTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDIN-----ADSAVN---------------RQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEYADNDEDKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKYVRKH-----DPLNSNIFSEAVKNKYNVGKQLSNEIIY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :.: .* .*:* * ** **.* :* :*:.::... ..:. : : :.:...: : .*:*. : *. ** *.*: .*** .*: : . * :::: :* * :: :. : .:**::*. .**.:*****::*** :. *** : **:*.*:: .: : :*:: : .****** :** * **::***.****** **:**:* : * . :** *:*:******.***::** *. : . :.: ::** * *: .* * **:*::******** ***: **:.: :******:***:*** :* :** : :. ::.* : ***:******.*.:*::* *:::*. . ** . :* * .:.:.: * : : ***:***:* *: .* **: ::* : ***.*.*****.:* :::. :*::**:**.**:** :**:*:*::::*.::** *********.: * *::*:: :*.::: :* : : * * . * : *: :* *: ", "identical_positions": 205, "similar_positions": 192, "identity": "24.15%" }, { "cls_id": "homologset.agr.SGD:S000002652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2M2R8-1", "uniprot_id": "PEX5_RAT", "id": "Q2M2R8-1", "name": "Peroxisomal targeting signal 1 receptor", "aln": "MAMRELVES-----------------------ECGGANPLMKLATHFTQDKALRQEGLRP-PWPPGASAAETVSKPLGVGTEDELVAEFLQDQNATLVSRAPQTFKMDDLLAEMQEIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVAQDYNETDWSQEF-IAEVTDPLSVSPARWAEEYLEQSEEKLWLGDPEGTSTTDRWYDEYHPEEDLQHTASDFVSKVDDPKLANSEFLKFVRQIGEGQVSLESAAG-----SGRAQAEQWAAEFIQQQGTSEAWVDQFTRPGNKLAALQVEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKG----YQFEEENPLRDHPQPFEEGLRRLEEGD-LPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSPAYAHLVAPGE--EGASGAGLGPSKRVLGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPR-GE----------GGAMSENIWSTLRLALSMLGQSDAYGAADA-RDLPALLTMFGLPQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09012-1", "uniprot_id": "PEX5_MOUSE", "id": "O09012-1", "name": "Peroxisomal targeting signal 1 receptor", "aln": "MAMRELVEG-----------------------ECGGANPLMKLATHFTQDKALRQEGLRPGPWPPGASAAETVSKPLGVGTEDELVSEFLQDQNATLVSRAPQTFKMDDLLAEMQEIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVAQDYNETDWSQEF-IAEVTDPLSVSPARWAEEYLEQSEEKLWLGDQEGSSTADRWYDEYHPEEDLQHTASDFVSKVDDPKLANSEFLKFVRQIGEGQVSLESAAG-----SGGAQAEQWAAEFIQQQGTSEAWVDQFTRPGNKIAALQVEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKG----YQFEEENPLRDHPQPFEEGLHRLEEGD-LPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSPAYAHLVAPGE--EGATGA--GPSKRILGSLLSDSLFLEVKDLFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPR-GE----------GGAMSENIWSTLRLALSMLGQSDAYGAADA-RDLSALLAMFGLPQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50542-1", "uniprot_id": "PEX5_HUMAN", "id": "P50542-1", "name": "Peroxisomal targeting signal 1 receptor", "aln": "MAMRELVEA-----------------------ECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEF-ISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEG-TATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAG-----SGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVN-TSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKG----YQFEEENPLRDHPQPFEEGLRRLQEGD-LPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAE--EGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPR-GE----------GGAMSENIWSTLRLALSMLGQSDAYGAADA-RDLSTLLTMFGLPQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C437-1", "uniprot_id": "PEX5R_MOUSE", "id": "Q8C437-1", "name": "PEX5-related protein", "aln": "MYQGHMQ-----------------------------------------------------------LVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSN--TAVLTTGLDLLDLSEPVSQPQTKAKKSEPSS------KSSSLKKKADGSDLISADAEQRAQALR-GPETSSLD-LDIQTQLEKWDDVKFHGDR--TSKGHLMAERKSCSSRTGSKELLWSAEHRSQPELSTGKSALNSESASELELVAPAQAR----------LTKEHRWGSALLSRN-----------------HSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQ-EAQNQVTVSASEKG----YYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNK---KGSPGLTRR----MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVP----------HPAISGNIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q925N3-1", "uniprot_id": "PEX5R_RAT", "id": "Q925N3-1", "name": "PEX5-related protein", "aln": "MYQGHMQG------------------------KGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSN--TAVLTTGLDLLDLSEPVSQTQTKAKKSESSS------KSSSLKKKADGSDLISADAEQRAQALR-GPETSSLD-LDIQTQLEKWDDVKFHGDR--TSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQAR----------LTKEHRWGSALLSRN-----------------HSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQ-EAQNQVTVSASEKG----YYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGNAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNK---KGSPGLTRR----MSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVP----------HPAISGNIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYB4-1", "uniprot_id": "PEX5R_HUMAN", "id": "Q8IYB4-1", "name": "PEX5-related protein", "aln": "MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIARPVTSN--TAVLTTGLDLLDLSEPVSQTQTKAKKSEPSS------KTSSLKKKADGSDLISTDAEQRGQPLR-VPETSSLD-LDIQTQLEKWDDVKFHGDR--NTKGHPMAERKSSSSRTGSKELLWSSEHRSQPELSGGKSALNSESASELELVAPTQAR----------LTKEHRWGSALLSRN-----------------HSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQ-EAQNQVTISASEKG----YYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSK---KGSPGLTRR----MSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVP----------HPAISGNIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32THI1-1", "uniprot_id": "A0AB32THI1_DANRE", "id": "A0AB32THI1-1", "name": "PEX5-related protein", "aln": "MYQGHLQG------------------------KDSRAADKTVAMVLKEIPNKASSEGKPLLTVTNKLVSEQQESRPLLSPSIDDFLCETKCDGAARPVTSN--TAVLSSSLDLLDLSEPGERRHSKDRKSPLSS------KSTPYRKKPDETELIQVDIEQSIPCSR-TPEKISLDSAAVPSSLDKWEELNPHPER--TGSRKWKLERRRSSKN--SGEFVWSMDCKPQLDTSHRN-SLEVNNKVEAEAGPVTQLNRQYVSGRHGRLSKEQRWGSTLLSRN-----------------QSLEEEFERAKAAVESDTEFWDKMQAEWEELARRNWLTENE-QPQIPSNVSPYEKG----YYFHTDNPFKDWPNAFEEGLRKSREGE-LPNAVLLLEAAVLQDPQDSEAWLVLGTTQAENENEQAAIVSLQRCLELHPNNLQALMALAVSLTNTGMRQEACEALLGWIRHNPKYKHLLKSRTHLQGSPGSRRP----SYPCPVSCPLLPEVKDLYLESAQQNVDTIDPDLQTGLGVLYNLSSEFNKAVDAFNAALSVRPEDYLLWNRLGATLANGDRSEEAVEAYTKALELQPGFIRSRYNLGISCINMGAHREAASNFLTALGLQRKSRSRQ-LS----------HQVMSGNIWAALRIALSMLDQPELFQAANI-GDLDLLMKAFNLDIAPLHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQ86-1", "uniprot_id": "A0A8M3AQ86_DANRE", "id": "A0A8M3AQ86-1", "name": "PEX5-related protein", "aln": "MYQGHSQE------------------------KDS----RAVAIVLKELPSKGSSDGKPLLTVTNKLCSEQQESRPLLSPSIDDFQSESKTDGATRAVTSN--TAVLSTTLDLVDLSEPCERRWSWDRRSPRGSRKNGFSKSSLRKKKTEETELIQVETEPSSPSRS-NPERASLDSVSS-SPLDKWEEVSLHPDSALNGGRKWRYERKRCTSNHSSSELLWSADFKTDFSNRHS--ALELSISTESDPGPAPQR-------------QKPQLGGSLLGRQ-----------------HSLEEEFVRAKAAVESDTEFWDKMQAEWEELARRNWLEDADSEGLVPLNFSPTEKG----YFFHANNPYKDYSNAFEQGQQKCRDGD-LNSAVLLLEAAILQDPQDSEAWQVLGTTQAENENEQAAIVCLQRCLELHPNNLKALMALAVSLTNTGQQPEACEALHRWIRYNPRYSHLLQDRSPLDGSPLPRRRGSSISRISTLGCSQLVEVLELYQEAVQLNTEEVDPDLQTGLGVLFNLSSEFDKAVIAFNAALSIRPEDYLLWNRLGATLANGDRSEEAVEAYTRALELQPGFIRSRYNLGISCINLGAHREAVSNFLTALHQQRKSRS---------------HKVMSSNIWAALRIALSLMGQPELFQAASV-GDLDLLMKAFNMDM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46085-1", "uniprot_id": "O46085_DROME", "id": "O46085-1", "name": "Peroxisomal targeting signal 1 receptor", "aln": "MVQSGIWRS------------------------------KPILWRIRFCAAIYFIIIRALCNTVTKPIASITADKQLRSISTSNTMSFRPLVEGDCGGVNPLMQLGGQFTRDVAHKDEGYVQRHFERAARPEDQLIN--EFLGQVTAPPQSFQMDTLLQEMRDINIH-GNPQQQMHSQQAEQWGQDFARGLAPALPNKMIHMQAQQQDLQHAQEFFDEPLISSQNFRSLPPLRQPLMPIAAGQQQDPFFDSAMETIITD-------HLPQAPQGESLDDWIS----------------DYQRSTEQKEQTAANFNEKFWERLQDEWQKLADE--NEHPWLSEYNDN--MDAYKE----YEFAEGNPMSDVENPFEKGKEYLSKGD-IPSAVLCFEVAAKKQPERAEVWQLLGTSQTENEMDPQAIAALKRAYDLQPDNQQVLMALAACYTNEGLQNNAVRMLCNWLTVHPKYQHLVAAHPELQAEGTSLAS-------SLIGPSKLRDLQQIYLEAVRQHPSEVDAEVQDALGVLYNLSGEFDKAVDCYQSALQVDPQNAKTWNRLGASLANGSRSVEAVEAYQQALQLQPGFIRVRYNVGVCCMNLKAYKEAVEHLLTALTMQAHTNAARELPNAAMAATFRGQNQMSESIWSTLKMVISLMGRSDLQSYVSD-RNLAALNEAFKD-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35056-1", "uniprot_id": "PEX5_YEAST", "id": "P35056-1", "name": "Peroxisomal targeting signal receptor", "aln": "MDVGSCSVG------------------------------------NNPLAQLHKHTQQNKSLQFNQKNNGRLNESPLQGTNKPGISEAFISNVNAISQENMANMQRFINGEPLIDDKRRMEIGPSSGRLPPFSN-------VHSLQTSANPTQIKGVNDISHWSQEFQGSNSIQNRNADTGNSEKAWQRGSTTASSRFQYPNTMMNNYAYASMNSLSGSRLQSPAFMNQQQSGRSKEGVNEQEQQPWTDQFEKLEKEVSENLDINDEIEKEENVSEVEQNKPE---------------TVEKEEGVYGDQYQSDFQEVWDSIHKDAEEVLPSELVNDDLNLGEDYLKYLGGRVNGNIEYAFQSNNEYFNNPNAYKIGCLLMENGAKLSEAALAFEAAVKEKPDHVDAWLRLGLVQTQNEKELNGISALEECLKLDPKNLEAMKTLAISYINEGYDMSAFTMLDKWAET--KYPEIWSRIKQQDDKFQKEKG--------FTHIDMNAHITKQFLQLAN-NLSTIDPEIQLCLGLLFYTKDDFDKTIDCFESALRVNPNDELMWNRLGASLANSNRSEEAIQAYHRALQLKPSFVRARYNLAVSSMNIGCFKEAAGYLLSVLSMHEVNTNNKKGDVG------SLLNTYNDTVIETLKRVFIAMNRDDLLQEVKPGMDLKRFKGEFSF-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * . . . . : :: . . : : . . : . . . ..*: :: : ::: . * * * : .:: * .* : : * :*.* :.* :.* ** *::** : .* .*... .*.*.* .: :** . * . .* * * * : . : . : .. . :*.::* **:*: ..:::::: .: :** : *:: **:***:***..:* **: ** :**:::*.::* ***:.:..:*: ..:**. :* .* : . . .: :*: .: :.: : .. :* : * ", "identical_positions": 66, "similar_positions": 129, "identity": "9.51%" }, { "cls_id": "homologset.agr.SGD:S000002654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69BT7-1", "uniprot_id": "TPPC4_RAT", "id": "Q69BT7-1", "name": "Trafficking protein particle complex subunit 4", "aln": "MAIFSVYVVNKAGGLIYQWDSYSPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGKYTADGKEVLEYPGNSANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAG------------------------IDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES56-1", "uniprot_id": "TPPC4_MOUSE", "id": "Q9ES56-1", "name": "Trafficking protein particle complex subunit 4", "aln": "MAIFSVYVVNKAGGLIYQWDSYSPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGKYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAG------------------------IDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y296-1", "uniprot_id": "TPPC4_HUMAN", "id": "Q9Y296-1", "name": "Trafficking protein particle complex subunit 4", "aln": "MAIFSVYVVNKAGGLIYQLDSYAPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGRYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCYQTLTGIKFVVLADPRQAG------------------------IDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLI9-1", "uniprot_id": "Q9VLI9_DROME", "id": "Q9VLI9-1", "name": "Trafficking protein particle complex subunit", "aln": "MIIYGVYIVSKSGGLIFNLDNNVPRIEHEKTFTYPLDLVLDYDSKKVSVSFNRKDGINVGHVLVAVNGMPVNGVTLDDGRDVRTTLDAPENYPINLKFSRPKMTTNEKIFLASMFYPLFAIASQLSPEPKSSGIEILEADTFTLHCFQTLTGIKFIIISETGLNG------------------------IDLLLRKVYELYSDYVLKNPFYSLEMPIRCELFDNKLQELLAQVEKTGISNIDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03784-1", "uniprot_id": "TRS23_YEAST", "id": "Q03784-1", "name": "Trafficking protein particle complex subunit 23", "aln": "MAIETILVINKSGGLIYQRN-------------FTNDEQKLNSNEYLILASTLHGVFAIASQLTPKALQLTQQTNIENTIPYIPYVGMSSNRSDTRNGGGNNNKHTNNEKLGSFKGDDFFKEPFTN--WNKSGLRQLCTDQFTMFIYQTLTGLKFVAISSSVMPQRQPTIATTDKPDRPKSTSNLAIQIADNFLRKVYCLYSDYVMKDPSYSMEMPIRSNLFDEKVKKMVENLQ---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : ::.*:****:: : :. * .: : :: :. : :. : . .: : . . * . . . . . . .:: *.*: * . . .**:. * :* *.:. :*****:**: ::.. * :***:* :***:.:*:* **:*****.:***:::: : : ", "identical_positions": 44, "similar_positions": 70, "identity": "18.11%" }, { "cls_id": "homologset.agr.SGD:S000002656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0J8-1", "uniprot_id": "GNTK_MOUSE", "id": "Q8R0J8-1", "name": "Gluconokinase", "aln": "-------MEAPGVLLVMGVSGSGKSTVGALLASKLG-----WKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQP--VVLACSALKKTYRDILIRGGSDAPLKSDDSAK-EPLAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPEN---FIQVSVDKSLPEITAAVMEALK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32PY9-1", "uniprot_id": "GNTK_RAT", "id": "Q32PY9-1", "name": "Gluconokinase", "aln": "-------METPGVLLVMGVSGSGKSTVGALLANKLG-----WKFYDADDYHSEENRIKMGKGVPLNDQDRIPWLCSLHDILLRDVASGQS--VVLACSALKKMYRDILNRGGSDVPPRSDESAKEEPLAGGKFLVVHLCGSFELIYGRLLQRRGHFMPPELLQSQFSILEPPSAPEN---FIHISVDKGLPEIAAAVLEALK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T6J7-1", "uniprot_id": "GNTK_HUMAN", "id": "Q5T6J7-1", "name": "Gluconokinase", "aln": "-------MAAPGALLVMGVSGSGKSTVGALLASELG-----WKFYDADDYHPEENRRKMGKGIPLNDQDRIPWLCNLHDILLRDVASGQR--VVLACSALKKTYRDILTQGKDGVALKCEESGKEAKQAEMQLLVVHLSGSFEVISGRLLKREGHFMPPELLQSQFETLEPPAAPEN---FIQISVDKNVSEIIATIMETLKMK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03786-1", "uniprot_id": "GNTK_YEAST", "id": "Q03786-1", "name": "Probable gluconokinase", "aln": "MTEKHKTMGKFKVIVLAGTAGTGKSTIAGELIHEFKDIYPDLKFIEGDDLHPPANVEKMTRGIPLNDDDRWDWLKKVAVESTKAAASTKEHLSIVACSSLKKKYRDLIR----------------HTCPESEFHFIFLYASKIEVLKRLKTRKGHFMKADMMESQFRDLELPDINDETDCDIVPLDFKTFYQIEKDVIQVVKSKVLNIE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .::: *.:*:****:.. * :: ** :.** *. * ** :*:**.*:** ** .: : .* : ::***:*** ***:: . :: .:.* .* : ** *.**** .::::*** ** * :: * * . :* :::.:* ", "identical_positions": 53, "similar_positions": 52, "identity": "25.36%" }, { "cls_id": "homologset.agr.SGD:S000002660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96K17-1", "uniprot_id": "BT3L4_HUMAN", "id": "Q96K17-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3I4-1", "uniprot_id": "D4A3I4_RAT", "id": "D4A3I4-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH7-1", "uniprot_id": "BT3L4_MOUSE", "id": "Q9CQH7-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PC91-1", "uniprot_id": "BT3L4_DANRE", "id": "Q6PC91-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLVVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAETKQLTEMLPGILSQLGADSLTSLRKLAEQFPRQVLDNKAPKAEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20290-1", "uniprot_id": "BTF3_HUMAN", "id": "P20290-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R5M7-1", "uniprot_id": "M0R5M7_RAT", "id": "M0R5M7-1", "name": "Transcription factor BTF3", "aln": "--------------------------------------------MKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNSISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLAAGEEE-EDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64152-1", "uniprot_id": "BTF3_MOUSE", "id": "Q64152-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPTQADSRGRGRARGGWPGAEATPSLP--LGGSRGRESQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KM15-1", "uniprot_id": "Q7KM15_DROME", "id": "Q7KM15-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGTVIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAAGSSAADAGDDDVPDLVENFEEVAIADTKEE------KSGEVAASA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPR2-1", "uniprot_id": "Q9VPR2_DROME", "id": "Q9VPR2-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNVEKLKRLQAQVRIGGKGTPRRKKKVMHQTAATDDKKLQSSLKKLSVSTIPGIEEVNIIKDDLTVIHFNNPKAQASLSANTFAVTGHGETRKVVEMLPDILPQLGQETVVQLRMYANAMNSQKGAPGSGDGPLPAEEDDDVPLLVGDFDEVAKVEATKQPVHEPKESAEIKAKDKQQQQPKKEQKQSAKVPETTNPSENPKEKQENKKGQAKNNKKGDPQTNKDKTNKSKDQAKGQPAPQANKETTQAAQALKQNPSKPAVQQKKDQVLAVDQKIEANGAIQKAQQPKPAETKSTDQKVEPKSAEKQVDKAKPIEQTKTKESKVEHPKPAQKQLDQNTQAKPTAERSEAKPVVPTPEPQKSAPPAVQTLAQIVALPAEKPANEAVAAPKAEEQKKDSSGPAKVEPAITPSAPQPVTTAEPPKSALKQDSPPKSAPKQGSPPKNVPKQESPPQSAPKQDSPPKGAPKQDSPPKGAPKQDSPPKGAPKQDSAPQQKTPPPVKQEVAPAKQDEPPAKQDAPPAKQDAPVPVPEVIKTLAPEVPNVSQAPAQPQGQAALASEKPADAPKAIEEPKAAPKKESPPPTKPVTATVPVAPATPAEAPSPLAPSTPPSTPTSVPPSAATVTPPSPATVTPPSPAVVTPPQKQSAAPQAGIKKQEAGTKTKQQQPANKPQQPQKQPPGGAGGSAGPGGNKGVQKQPNPNAKPAVAPKPAQATPKPAAASPKASPNQTNPQQQQGKAANKASPPKQTGPTGGQQKSAANASKATASPKSAASPKATSPKAGTPTNPASASGGPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40314-1", "uniprot_id": "NACB2_YEAST", "id": "P40314-1", "name": "Nascent polypeptide-associated complex subunit beta-2", "aln": "--------------------------------------------MPVDQEKLAKLHKLSAANKVGGTRRKINKKGNLYNNNDKDNTKLQAELHKLHPMTIENVAEANFFKKNGKVLHFNSAVVQIAPQCNLTMIHGQPKENTLNGLYPSVASQLGSQELEYLTGLAHNLENE---------------QTVLDQLGDRCSETKQQVMNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :*.* ::**. .** :: . *:.*** .*:** .* .: *.*::..: .*:***.. .* : * : *: : . : : *.: *** : : * * : : : : * .*. . ", "identical_positions": 33, "similar_positions": 46, "identity": "3.91%" }, { "cls_id": "homologset.agr.SGD:S000002663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YQ7-1", "uniprot_id": "RMD5B_MOUSE", "id": "Q91YQ7-1", "name": "E3 ubiquitin-protein transferase RMND5B", "aln": "MEQ----CACVERELDKVLHKFLTYGQHCEQ----------SLEELLHSVGQLRAELASA--ALQGTPLSATLSLVMS------------------QCCRKIRDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDSRE--KQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDF------KQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELN---SSLEFKLHRLHFIRLLAGGPEKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDNS--HWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWSHKDELPIEIELG-MKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG--KLKCPYCPMEQNPADGKRIIF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G75-1", "uniprot_id": "RMD5B_HUMAN", "id": "Q96G75-1", "name": "E3 ubiquitin-protein transferase RMND5B", "aln": "MEQ----CACVERELDKVLQKFLTYGQHCER----------SLEELLHYVGQLRAELASA--ALQGTPLSATLSLVMS------------------QCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDARE--QQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDF------KQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELN---SSLEFKLHRLHFIRLLAGGPAKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSS--HWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDELPIEIELG-MKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG--KLKCPYCPMEQNPADGKRIIF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H871-1", "uniprot_id": "RMD5A_HUMAN", "id": "Q9H871-1", "name": "E3 ubiquitin-protein transferase RMND5A", "aln": "MDQ----CVTVERELEKVLHKFSGYGQLCER----------GLEELIDYTGGLKHEILQS--HGQDAELSGTLSLVLT------------------QCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQAD----SQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQ------KEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQN---SSLEFKLHRLYFISLLMGGTTNQREALQYAK-NFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDAN--QWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLG-KKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGS--KLKCPYCPMEQSPGDAKQIFF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M194-1", "uniprot_id": "A0ABK0M194_RAT", "id": "A0ABK0M194-1", "name": "", "aln": "MDQ----CVTVERELEKVLHKFSGYGQLCER----------GLEELIDYTGGLKHEILQS--HGQDAELSGTLSLVLT------------------QCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQAD----SQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQ------KEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQN---SSLEFKLHRLYFISLLMGGTTNQREALQYAK-NFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDAN--QWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLG-KKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGS--KLKCPYCPMEQSPGDAKQIFF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YQ8-1", "uniprot_id": "RMD5A_MOUSE", "id": "Q80YQ8-1", "name": "E3 ubiquitin-protein ligase RMND5A", "aln": "MDQ----CVTVERELEKVLHKFSGYGQLCER----------GLEELIDYTGGLKHEILQS--HGQDAELSGTLSLVLT------------------QCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQAD----SQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQ------KEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQN---SSLEFKLHRLYFISLLMGGTTNQREALQYAK-NFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDAN--QWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLG-KKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGS--KLKCPYCPMEQSPGDAKQIFF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W2N5-1", "uniprot_id": "Q9W2N5_DROME", "id": "Q9W2N5-1", "name": "", "aln": "MDSESLACSSVEKDLTRVVSKLEQLHENAEADIGDIATQMSELVEVLSRAEQLVTTLNSSTQVSQDDPMGDAVSMQVETEPTAPQRLTERQVESVRNALARCHERVQKLSTEHRDLHGSISKIGKAIDRNFSADFSSTMRVDVLQDEE---NLMLLNKAIAKHYCRQGMDDVARTLIRECKMSPEHAQDVFD-SEREFADIYGIWVKIQKRDLTDALKWAKMYSQQLSDRH---SLIEFRLHRMRFMQLVSYGLDSQREAISYARLNFKKFAVRYEHEIANLMASFIYLPSGLENSPYKHFLGQE--KWTELSFIFLKDACQLLGISKNSALSVVVNAGCTALPALLNIKQVMQSRQVLGMWNGCDELPIEIDLQ-PEFRFHSIFACPILRQQTSEDNPPKKLTCGHVISNDALHKLSVGH--ILKCPYCPVEQNAEEAVRIYF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12508-1", "uniprot_id": "RMD5_YEAST", "id": "Q12508-1", "name": "E3 ubiquitin-protein ligase RMD5", "aln": "MSEL---LDSFETEFAKFYTDSNLEETNLQKCLDHTHEFKSQLKKLKAHLNKHIQESKPEVYNKLSDKEKQKFKRKRE------------------LIIEKLSKSQRQWDHSVKKQIKYVSQQSNRFNKSTLNKLKEFDIDSVYVNKLPKETMENVNEAIGYHILRYSIDNMPLGNKNEAFQYLKDVYGITNKESTEFIEMGQIVHDLKKGDTESCLKWCSNEMESLSSNHTALSSLKFDLYTLSAMQIVKHG---NPVELYYQITQNAPLDCFRHREKELMQNVVPLLTKSLIGQPIEDIDSKVNKELKECTSLFIKEYCAAKHIFFDSPLFLIVLSGLISFQFFIKYKTIRELAHVD--WTTKDELPFDVKLPDFLTHFHPIFICPVLKEETTTENPPYSLACHHIISKKALDRLSKNGTITFKCPYCPVNTSMSSTKKVRFVML", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. .* :: :. . : * :: . .. : . :: . :. :*: .: :::. .: :: .: * : .: .:. .*. . . * :: * :: .*:*. : * : * ::* *: : : :: * : : * : : .:: : . * .: .* .: . . : * :: * : :*.* : . :* :: ::: * : : : *. ****:::.* :*.:* **:*:::*: .*** .* * *:**..**.:: . :******:: . . :: * ", "identical_positions": 53, "similar_positions": 123, "identity": "11.86%" }, { "cls_id": "homologset.agr.SGD:S000002664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04762-1", "uniprot_id": "CATA_RAT", "id": "P04762-1", "name": "Catalase", "aln": "MADSRDPASDQMKQWKEQRAPQKPDVLTTGGGNPIGDKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHLKDPDMVWDFWSLCPE--SLHQVTFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRDLFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEVEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVAN-YQRDGPMCMHDNQGGAPNYYPN--SFSAPEQQG--SALEHHSQCSADVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIANHLKDAQLFIQRKAVKNFTDVHPDYGARVQALLDQYNSQKPKNAIHTYVQAGSHIAAKGKANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24270-1", "uniprot_id": "CATA_MOUSE", "id": "P24270-1", "name": "Catalase", "aln": "MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVAN-YQRDGPMCMHDNQGGAPNYYPN--SFSAPEQQR--SALEHSVQCAVDVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYGARIQALLDKYNAEKPKNAIHTYTQAGSHMAAKGKANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04040-1", "uniprot_id": "CATA_HUMAN", "id": "P04040-1", "name": "Catalase", "aln": "MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVAN-YQRDGPMCMQDNQGGAPNYYPN--SFGAPEQQP--SALEHSIQYSGEVRRFNTAN-DDNVTQVRAFYVNVLNE-EQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PT92-1", "uniprot_id": "CATA_DANRE", "id": "Q9PT92-1", "name": "Catalase", "aln": "MADDREKSTDQMKLWKEGRGSQRPDVLTTGAGVPIGDKLNAMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHVGKTTPIVVRFSTVAGEAGSPDTVRDPRGFAVKFYTDEGNWDLTGNNTPTFFIRDTLLSPSFIHSQKRNPQTHLKDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTNQGIKNIPVEEADRLAATDPDYSIRDLYNAIANGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKEFPLIPVGRFVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYRTRVAN-YQRDGPMCMHDNQGGAPNYYPN--SFSAPDVQP--RFLESKCKVSPDVARYNSAD-DDNVTQVRTFFTQVLNE-AERERLCQNMAGHLKGAQLFIQKRMVQNLMAVHSDYGNRVQALLDKHNAEGKKNTVHVYSRGGASAVAAASKM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17336-1", "uniprot_id": "CATA_DROME", "id": "P17336-1", "name": "Catalase", "aln": "MAG-RDAASNQLIDYKNSQ-TVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPE--SAHQVCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIEN-FQRDGAMNVTDNQDGAPNYFPN--SFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDK-CAKKRLVQNIAGHLSNASQFLQERAVKNFTQVHADFGRMLTEELNLAKSSKF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLI6-1", "uniprot_id": "Q9VLI6_DROME", "id": "Q9VLI6-1", "name": "", "aln": "MCS-RDTASNQLIDYKNND-SEVQREITTSSGTPVGVKDAIQTVGPRGPALLQDFQFLDEVMHFDSERIPERVAYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGFAVKFYTDDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHLKDPDMFWDFMTLRPE--TLHALLMYFSDRGTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAIRDLYNSIKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFTEVEQLAFSPAHMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVNCPYRVNVRN-FQRDGAMTVTDNQNGAPNYFPN--SFCGPRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDN-CGRKRLVRNLSEHLTEASQFLQERAVKLFTMVHSDFGRLMTEALNTARISKF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15202-1", "uniprot_id": "CATA_YEAST", "id": "P15202-1", "name": "Peroxisomal catalase A", "aln": "-----MSKLGQEKNEVNYSDVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKKVAEAKHASELSSNSKF----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : :*.. * *:. * :** *:** : *.: **: *.**:* :*:*:******* *.**: . : :*.:: * * ***.. *: **.**.*: ****.****::* * . * * .::**. * ::*:*******:*:*.**.*** : : : * : : ***** * .: ::**. **:: * .*: * :.* **:*****: . .: :*** :**:: * . ::***:.***.* .:*:. :. **:****.: ::** **::**:.** *:*::*** ** *: * *.*.* :*:.***:* *::*:*** *: ::****** .. * ***.* : .* .. *.* .* *: . . :: :. : :. *. :: .: ::.* *:. *: * :*.: . : *. . . : : . . ", "identical_positions": 167, "similar_positions": 151, "identity": "31.16%" }, { "cls_id": "homologset.agr.SGD:S000002665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSK5-1", "uniprot_id": "SETD6_RAT", "id": "D3ZSK5-1", "name": "N-lysine methyltransferase SETD6", "aln": "MAAPAKRARVS---DASPLAAPCPVPRAAARVPLPLPAGPSGHEPESDAVAGFLRWCTRVGLELSP-KVLVSRQGTVAGYGMVARESVQPGELLFAVPRSALLSPHTCSISDLLERERGALQSLSG-WVPLLLALLHELQAP--ASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPTVRSLELYRQLVALVMAYSFQEPLE-----EEEDEKEPN--------SPLMVPAADILN-HIANHNANLEYSAEYLRMVATQPILKGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVAVREAALQGTEDETERL-LLCERWDFLCKQELVGEEGAFVIGREEVLTEEELATTLKVLCMPAEEFRDYK--ERAGWGEEETEDGS-----LAITNIPKLQESWKRLLRDSVLLTLQTYATDLKTEQDLLSNKEVYAKLSWREQQALQVRYGQKMILHRLLELTS-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWY3-1", "uniprot_id": "SETD6_MOUSE", "id": "Q9CWY3-1", "name": "N-lysine methyltransferase SETD6", "aln": "MAAPAKRARVS---GGSPLVAPCPSPR-AARAPLPLPAGSSGGEPEGDAVAGFLRWCRRVGLELSP-KVTVSRQGTVAGYGMVARESVRAGELLFAVPRSALLSPHTCSISGLLERERGALQSLSG-WVPLLLALLHELQAP--ASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPSVRSLELYQQLVALVMAYSFQEPLE-----EDDDEKEPN--------SPLMVPAADILN-HIANHNANLEYSADYLRMVATQPILEGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVTVRDAALQGTKDETEKL-LVCERWDFLCKQEMVGEEGAFVIGCEEVLTEEELATTLKVLCMPAEEFRDYK--ERAGWGEEETEDDS-----LAITDIPKLQESWKRLLRNSVLLTLQTYTTDLKTDQDLLSNKEAYATLSWREQQALQVRYGQKMILHRVLELTN-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBK2-1", "uniprot_id": "SETD6_HUMAN", "id": "Q8TBK2-1", "name": "N-lysine methyltransferase SETD6", "aln": "MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVS--ERAGGRRT---RGGARAALTSPPAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSG-WVPLLLALLHELQAP--ASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLE-----EEEDEKEPN--------SPVMVPAADILN-HLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERH-LVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELK--DQDGGGDDKREEGS-----LTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803K4-1", "uniprot_id": "SETD6_DANRE", "id": "Q803K4-1", "name": "N-lysine methyltransferase setd6", "aln": "MATEAKRPKTGD--EKSVLEPLNNFLLWCESVQLTLS-----------------------------DKVYLSKEGTAAEYGMLAKEDIEEGHVLFTIPREALLHQGTTKVKKVLEEGKKCLESASG-WVPLLLSLMYEYTSS--TSHWKPYLSLWPDFRTLDQPMFWSEEECDKLLKGTGIPESVITDLRKLQDEYNSVVLPFMKSHPDLWDPEKHNLELYKSLVAFVMAYSFQEPVEDDDEDEEDDEKKPN--------LPMMVPMADMLN-HISKHNANLEYTPECLKMVSIRRIGKGEEVFNTYGQMANWQLLHMYGFAEPFPNNINETADIKMASVYKAAAQVARSEANQQ-LLEDKWKMLCEMEVVGEKGVFIFGQSGSLTYHELYTTLKVLCMSSQIFEDFR--ENEGWEEDDEDDDDKMEQDLSFEGLASLSVEWKRLLCVAATETLDSYNEDVETDRRLMEDQRALAELSSRERRALYVRLGQKNILQRIQQLTKPAS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12504-1", "uniprot_id": "RKM4_YEAST", "id": "Q12504-1", "name": "Ribosomal lysine N-methyltransferase 4", "aln": "MDDFSR-----------DTENFVCWLKTTAEIEVSPK------------------------------IEIKDLCCDNQGRAVVATQKIKKDETLFKIPRSSVLSVTTSQLIKDYPSLKDKFLNETGSWEGLIICILYEMEVLQERSRWAPYFKVWNKPSDMNALIFWDDNE-LQLLKPSLVLERIGKKEAKEMHERIIKSIKQIGGEFSRVATS-FEFDNFAYIASIILSYSFDLEMQDSSVNENEEEETSEEELENERYLKSMIPLADMLNADTSKCNANLTYDSNCLKMVALRDIEKNEQVYNIYGEHPNSELLRRYGYVE-WDGSKYDFGEVLLENIVEALKETFETNTEFLDRCIDILRNNANIQEFLEGEEIVLDSYDCYNNGELLPQLILLVQILTILCQIPGLCKLDIKAMERQVERIVKKCLQLIEGARATTNCSATWKRCIMKRLADYPIKKCVSIEKPSKGNSLTREELRDVMARRVLKSEIDSLQVCEETIDKNYKVIPDEKLLTNILKRKLTEEEKSSVKRPCVKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : . .::* :.:. .. ** :** ::* * .: : : . :* * *::.:::* * * **: :* . :: :** ::* **: : : * : .. : * : : .. . .:: : :.:::::***: :: *:::*: .: *:* **:** . :: **** * .: *:**: : * :..:::* **: .* :*:: **:.* : .. : .:: : : .* : . ::: : .: : . * :::. . ** . * :* : : . . . : * : . . . * * . .. .. . : . *: * * .: *: : . ", "identical_positions": 65, "similar_positions": 142, "identity": "12.08%" }, { "cls_id": "homologset.agr.SGD:S000002666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTT2-1", "uniprot_id": "CLPB_RAT", "id": "Q9WTT2-1", "name": "Mitochondrial disaggregase", "aln": "-----------------------------------------------------------------------MMLSAVLRRTAPAPRLFLGLIKSPSLQSRGGAYNRSVITGDRGEPQRLRTAAWVRPGASSVLFPGRGAATGGRRGE----------------------------RTEIPYLTAASSGRGPSPE------------------------------ETLPGQDSWNGVPNKAGLGMWALAMALVVQCYNKNPS-----NKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVAAISHNESVVQVLLAAGADPNLGDDFSSVYKTANEQGVHSLE------------------------------VLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLGGGANPLQRNEMGHTPLDYAREGEV-MKLLKTSETKYMEKQRKREAE---------------------------------ERRRFPLEQRLEQHIIGQESAIATVGAAIRRKENGWYDEEHPLV-FLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYIGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENMIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVQYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRPPTLRLEIIDKDSKTHKLDIQAPLHPEKVCYTI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60649-1", "uniprot_id": "CLPB_MOUSE", "id": "Q60649-1", "name": "Mitochondrial disaggregase", "aln": "-----------------------------------------------------------------------MMLSAVLRRTTPAPRLFLGLIKSPSLQSRGGAYGRGVVTGDRGEPQRLRAAAWVRPGASSTFVPGRGAATWGRRGE----------------------------RTEIPYLTAASSERGPSPE------------------------------ETLPGQDSWNGVPNKTGLGMWALAMALVVQCYSKNPS-----NKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQGVHSLE------------------------------VLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDYAREGEV-MKLLKTSETKYMEKQRKREAE---------------------------------ERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLV-FLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYIGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQMSDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKHLLKSPELPSPQAEKRPPTLRLEIIDKDSKTRKLDIQAPLHPEKVCYTI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H078-1", "uniprot_id": "CLPB_HUMAN", "id": "Q9H078-1", "name": "Mitochondrial disaggregase", "aln": "-----------------------------------------------------------------------MLGSLVLRRKALAPRLLLRLLRSPTLRGHGGASGRNVTTGSLGEPQWLRVATGGRPGTSPALFSGRGAATGGRQGG----------------------------RFDTKCLAAATWGRLPGPE------------------------------ETLPGQDSWNGVPSRAGLGMCALAAALVVHCYSKSPS-----NKDAALLEAARANNMQEVSRLLSEGADVNAKHRLGWTALMVAAINRNNSVVQVLLAAGADPNLGDDFSSVYKTAKEQGIHSLEDGGQDGASRHITNQWTSALEFRRWLGLPAGVLITREDDFNNRLNNRASFKGCTALHYAVLADDYRTVKELLDGGANPLQRNEMGHTPLDYAREGEV-MKLLRTSEAKYQEKQRKREAE---------------------------------ERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLV-FLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKLRLEIIDKDSKTRRLDIRAPLHPEKVCNTI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT32-1", "uniprot_id": "A0A8M3AT32_DANRE", "id": "A0A8M3AT32-1", "name": "Mitochondrial disaggregase", "aln": "-----------------------------------------------------------------------MFLSSVPARVFIRRSRSLSPCR--ALHTSHGEAARFRNLEPNRSPVLKRSGVIEETHAQYHQLASRWRANLESR------------------------------RSSWASLTAAGRSRG--------------------------------------GHQSS-GKTAASATGAGLISAAALTFCFKKDND-----DKAEAFLEAARSNDTEEIRRLLSEGLDPNTRHRLGWTALMVAAMNTQHNVVKLLLDAGADPNLGDGFSSVYDTAREKSLHSLE------------------------------VLVSREDEFSSRLSSRASFRGCSALHYAALADDLQTVRLLLDAGADPSLKNDLGHTPLSYARDGEL-SAVLRDAQDTFAEAQRKREAE---------------------------------ERRKFPLERRLKEHIIGQEGAINTVASAIRRKENGWYDEEHPLV-FLFLGSSGIGKTELAKQVARYMHKDIKKGFIRMDMSEFQEKHEVAKFIGSPPGYVGHDEGGQLTKQLKQSPSAVVLFDEVEKAHPDVLTVMLQLFDEGRLTDGKGKTIECKDAIFIMTSNAASDEIAQHALQLRQEAQEQSRRRLAENLDDVQKSENITISNTFKEQVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELLQLVSRELHYWAKKAKQRHNITLLWERPVLELLVKGYNLHYGARSIKHEVERRVVNQLAAAFEQELLPKGCTLRLTVDRDS------------QHTDGAPVLRLELLQEDKTSRKLEIQPPLNPQDTAHTPRKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33416-1", "uniprot_id": "HSP78_YEAST", "id": "P33416-1", "name": "Heat shock protein 78, mitochondrial", "aln": "MLRQATKAPIQKYLQRTQLLRRSTPRIYTIVQCKRSICSFNARPRVANKLLSDIKTNALNEVAISTCALKSSYGLPNFKRTYVQMRMDPNQQPEKPALEQFGTNLTKLARDGKLDPVIGRDEEIARAIQILSRRTKNNPCLIGRAGVGKTALIDGLAQRIVAGEVPDSLKDKDLVALDLGSLIAGAKYRGEFEERLKKVLEEIDKANGKVIVFIDEVHMLLGLGKTDGSMDASNILKPKLARGLRCISATTLDEFKIIEKDPALSRRFQPILLNEPSVSDTISILRGLKERYEVHHGVRITDTALVSAAVLSNRYITDRFLPD-KAIDLVDEACAVLRLQHESKPDEIQKLDR--------AIMKIQIELESLKKETDPVSVERREALEKDLEMKNDELNRLTKIWDAERAEIESIKNAKANLEQARIELEKCQREGDYTKASELRYSRIPDLEKKVALSEKSKDGDKVNLLHDSVTSDDISKVVAKMTGIPTETVMKGDKDRLLYMENSLKERVVGQDEAIAAISDAVRLQRAGLTSEKRPIASFMFLGPTGTGKTELTKALAEFLFDDESN-VIRFDMSEFQEKHTVSRLIGAPPGYVLSESGGQLTEAVRRKPYAVVLFDEFEKAHPDVSKLLLQVLDEGKLTDSLGHHVDFRNTIIVMTSNIGQDILLN----------------------DTKLGDDGKIDTATKNKVIEAMKRSYP--PEFINRIDDILVFNRLSKKVLRSIVDIRIAEIQDRLAEKRMKIDLTDEAKDWLTDKGYDQLYGARPLNRLIHRQILNSMATFLLKGQIRNGETVRVVVKDTK----------------------LVVLPNHEEGEVVEEEAEK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * .* * .. . . . . * *. * . :: . * :: : : . . ::: . .: .: * *.* : : :: ***: *:: :. :.. :* :* * .:* .*. ..:: * : *.: :.. *. : . . : : . : :: :. . : : .*:: .*: : : . ::.::.: : * : :*. *:::::**: ** ::. *:* :. * .*::*:. *:***.:* *****:* *.::..* .: .**:*******:* *:::**:****: :.*****: ::: * *******.:****** .::**::***:***. *: :: :::*::**** ..* : : *.: .:. .*.. *:::*..: ::: **:.**::*: * :.:. * .:*. .: .: ::: * :. : .**: ****.::: :.*:::*.:*: : : * *:*:.*. . * :: :.. . :: .. ", "identical_positions": 128, "similar_positions": 223, "identity": "14.56%" }, { "cls_id": "homologset.agr.SGD:S000002671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4W8-1", "uniprot_id": "A0A0G2K4W8_RAT", "id": "A0A0G2K4W8-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILVFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARECFTRSVNITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLGMCK--QLGDVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMN-ITVPEDYITGFIRANNTFLYQLVFDPIQRKLIPLNAYGDDVNPETLT-YAGQYVNDS-VALQIALGNRDINTFEQIDDYS---PDT-MPAHSRSHSWNDKACQKSPVASSIWHKNYCPRLEVNSVSHAPQLKEKPSTVGLKQVISTKGLNLPRKPCVLKRPR-NEALSEDDLLSQYS-SLTKKIRENSCGNGTSPNSSEMSVPCPDGGTAHKTDAHTPSRTRNKFATFLQRRNEECGAIVVPGTKSRFFCSSPDFDNFIPKKGSNQPPNETVATGKATTSLLGALDCPDTGGQKPVVTNGTHS-----PNTHIPGD-----ATGSPKDEAQSSETSKFLGTMSPPTLGTLRSCFSWSGTLGEFSRTPSPSTRSTLQQFRRKSEPPACLPEACAVT-DVCDSKSGTLGDKSQSLHELDWSSRSQESIDSTCS-LNTSSLSQPSSKDSDSEESDCNNKSLDNQGSQNSKQHLPHFPK-----KDILGRNKVPGLCRSSSMDSLSATKIKPLVPARVSGLSKKPGSIQKRKHHDAENKPGLQIKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECARAQRAIFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ11-1", "uniprot_id": "EXO1_MOUSE", "id": "Q9QZ11-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIQEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILIFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARDCFARSINITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLGMCK--QLGDVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLRMN-ITVPEDYITGFIRANNTFLYQLVFDPIQRKLVPLNAYGDDVNPETLT-YAGQYVGDS-VALQIALGNRDVNTFEQIDDYS---PDT-MPAHSRSHSWNEKAGQKPPGTNSIWHKNYCPRLEVNSVSHAPQLKEKPSTLGLKQVISTKGLNLPRKSCVLKRPR-NEALAEDDLLSQYS-SVSKKIKENGCGDGTSPNSSKMSKSCPDSGTAHKTDAHTPSKMRNKFATFLQRRNEESGAVVVPGTRSRFFCSSQDFDNFIPKKESGQPLNETVATGKATTSLLGALDCPDTEGHKPVDANGTHN-----LSSQIPGN-----AAVSPEDEAQSSETSKLLGAMSPPSLGTLRSCFSWSGTLREFSRTPSPSASTTLQQFRRKSDPPACLPEASAVVTDRCDSKSEMLGETSQPLHELGCSSRSQESMDSSCG-LNTSSLSQPSSRDSGSEESDCNNKSLDNQGEQNSKQHLPHFSK-----KDGLRRNKVPGLCRSSSMDSFSTTKIKPLVPARVSGLSKKSGSMQTRKHHDVENKPGLQTKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECVRAQRAIFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ84-1", "uniprot_id": "EXO1_HUMAN", "id": "Q9UQ84-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCR--QLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMN-ITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLS-YAGQYVDDS-IALQIALGNKDINTFEQIDDYN---PDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR-SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSS-DSTDCVSNKVSIQPLDETAVTDKENN--LHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSE-ESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSK-----KDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKK--PLSPVRDNIQLTP-EAEEDIFNKPECGRVQRAIFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803U7-1", "uniprot_id": "EXO1_DANRE", "id": "Q803U7-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKDASEPMHVKKYRGQTVAVDTYCWLHKGAFSCAEKLAKGEPTDQYVSYCMKFVDMLLSFGVKPILVFDGRNLPSKQEVEKSRRERRQANLQKGKQLLREGKITEARECFTRSVNITPSMAHDVIRAARTRGVDCVVAPYEADAQLAFLNKSDIAQAVITEDSDLLAFGCKKVILKMDKQGNGLEIEQCHLGRCK--SLGNIFTEEKFRYMCILSGCDYLQSLYGIGLGKACKLLRMANNPDILKVIKKMGQYLKMD-ISVPEEYIEGFTKANNTFLYQLVFDPLRRKVVPLNPYPDHINPAALS-YAGTNVGDE-KGLQMALGNLDINTMQRIDDFNPDAPQTQPPKAPRSSSWNDRCDKTATTQASIWSQNYEPGCTKSQSPTSP--KRPPPTRGKERIVSVQSLKLPQRESQVKRPREDTSLSVDDLLEQYTAGVKRHCPETQPTTKPLTNDNKVSKENHCGSTSG------PFRPRNRFATLLQWRNRSEEGTEEQGTCSRFFCHD-ESNIAETQEDSKQDSSQSVES--------QEKHVSQSGGDTSSLCEEPER---------------------EQDKDEPSSPPASPSCSSRPASVG--LGVFSWSGTTKELNKSVSHPARDSTERQR-SSSTPSGLSTLQQFHRNKARISWAGPG-LSLSSSPVEGSEDAGNSPGSPPS-QDSAYFSQSSSISASVENSLVTEDNSDKEKERDSVVSNSPSSSPLDRLKPAVNRTKVSGLSRKGACGQGKGGKIETSAPARASGLRRKPS---GKKNVNNENSPGLQATISGLWGAFSFKKDSPKLSATKKGEPMSPVGENVVMETTQADKEIFIIAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24558-1", "uniprot_id": "EXO1_DROME", "id": "Q24558-1", "name": "Exonuclease 1", "aln": "MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLVEAEKLHLAMG-CTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIALKKIPSYLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSWT------------PEKAWPTPKNVKRSKHKSIWQTNFQSENTHTPK------KENPCALFFKKVDFVG--KTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSREDSVDQERTPPPSPVHKSR--------------HNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPLDGEAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQTRLQREHLR-----------------------DTENDDMDEQKLSSHSG----------------HKKLRLVCKDIPGKNPIRQRCSSQISDGETDTDTTASSLLESQDKGVPSPLESQEDLNNSQPQIPTEGNTNS-----TTIRIKSLDLLLENSPEPTQESDRNNNDAIILLSDDSCS--------------SDQRASSTSSSSQQRQNFLPTSKRRVGLSKPSTAKKGTPKSRTNGKLGAVSQNQTKLSMFGFQTKPVLK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12086-1", "uniprot_id": "DIN7_YEAST", "id": "Q12086-1", "name": "DNA damage-inducible protein DIN7", "aln": "MGIPGLLPQLKRIQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPTNKYLQFFIKRLQLLKRLKIKPYIVFDGDSLFVKNHTETRRRKKRLENEMIAKKLWSAGNRYNAMEYFQKSVDITPEMAKCIIDYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISEDSDLLVFGCKTLITKLNDQGKALEISKDDFSALPENFPLGELSEQQFRNLVCLAGCDYTSGIWKVGVVTAMKIVKRYSEMKDILIQIERTEKLCFS-----KAFKQQVEFANYAFQYQRVFCPLSNQITTLNNIPKAVTNSHAEIIKIMKCIGS---------VVERGSGVRKDVIN-------------------TKNIDHKVHEMIAKGELHP------------------------------VDMASKLINRERKLKARKLFKVGLLGGESNSFNKKVEQPLVDTQDVLSERE-----------------------NSLDNKNASSIYMTSPAAISGTVPSIF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **: : .. : ::. ..:*:* *.***:. .** :*. .: *: *: : :* :::* :** ::*** * * .* **. * . . :* *. :* . : :.:::* ** :* .: .: :***:***.*:.:*:: .: * :*:***** **.*.:* *:: *..* :. : ::** : *:**** .: :*: .* *.: .: . : * : . : . *: :* : :: *: .:: * . .. : : : * . * : . . . :: *: : .:: * : . . . : ", "identical_positions": 77, "similar_positions": 122, "identity": "8.88%" }, { "cls_id": "homologset.agr.SGD:S000002672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU37-1", "uniprot_id": "E9PU37_RAT", "id": "E9PU37-1", "name": "Palmitoyltransferase", "aln": "----MEGPG------LGSQCR----NHSHGS-HVPG---FG------QHGICAHENKELAKAKEILPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPD---RENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQ-----SVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSAVDKTHQNTPLHWAVAAGNVSAVD-KLLEAGSSLDLRNAKGETPLDMAVQNKNQLIVHMLRTEAKMRANKKF----RLWQWLHKCELFLLLVLS---MISLWAVGYILNFNSDSWLLKGCLLVALLFLTSLFPRFLVGYK---------NLVYLPTVFLLSSIFWIFMTWFILFFPDAAGSP--FYFAFIFSIMAFLYFFYKTWATDPGFTKASEEER--KVNIVTLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWS---NHCATTFKEDGLWTYLNQIVACS-----PWVLYIFMLAAFHFSWSTFLLINQLFQIAF-------------------LGLTSHERISLLKQSRHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCI--IDWTSQYTMVFHPAKEKVLRSV---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU2-1", "uniprot_id": "ZDH13_MOUSE", "id": "Q9CWU2-1", "name": "Palmitoyltransferase ZDHHC13", "aln": "----MEGPG------LGSQCR----NHSHGS-HVPG---FG------RHGICVHENKELAKAKEILPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPD---RENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQ-----SVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSVVDKTHQNTPLHWAVAAGNVSAVD-KLLEAGSSLDIRNAKGETPLDMALQSKNQLISHMLRTEAKMRANKQF----RLWRWLHKCELFLLLILS---MITLWAVGYILDFNSDSWLLKGCLLVALFFLTSLFPRFLVGYK---------NLVYLPTVFLLSSIFWIFMTWFILFFPDTAGSP--LYFAFIFSIMAFLYFFYKTWATDPGFTKASEEER--KVNIVTLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWS---NHCATTFKEDGLWTYLNQIVACS-----PWVLYIFMLAAFHFSWSTFLLINQLFQIAF-------------------LGLTSHERISLLKQSRHMKQTLSLRKTPYNLGFTQNLADFFQCGCFGLVKPCI--IDWTSQYTMVFHPAKEKVLRSV---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUH4-1", "uniprot_id": "ZDH13_HUMAN", "id": "Q8IUH4-1", "name": "Palmitoyltransferase ZDHHC13", "aln": "----MEGPG------LGSQCR----NHSHGP-HPPG---FG------RYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPD---KENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQ-----SVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVD-KLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQKF----RLWRWLQKCELFLLLMLS---VITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYK---------NLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAP--FYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEK--KVNIITLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLS---SHCATTFKEDGLWTYLNQIVACS-----PWVLYILMLATFHFSWSTFLLLNQLFQIAF-------------------LGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCV--VDWTSQYTMVFHPAREKVLRSV---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IQZ2-1", "uniprot_id": "ZDH13_DANRE", "id": "A0A0R4IQZ2-1", "name": "Putative palmitoyltransferase ZDHHC13", "aln": "-MDWSEGDGSHSHGHMGDSCHGHGGGHSHGHGHSHGGSGFGGFMPAGFHGQLVPGPMDPTQQPRKSSHPEDSSSWDIIKATQFGALERCKELVEAGYDVRQPD---KENVTLLHWAAINNRADIVKYYISKGAVIDQLGGDLNSTPLHWAIRQGHLSMVIQLMRYGADPSLADGEGYRGLHLAVLFQNMPIAAYLMAKGQ-----EVDLPDLNGQTPLMLAAQKIIGPEPTNFLIKCNASVNAVDKVNRNSPLHCAVLAGNVDSVH-ILLEAGASVDMQNDNGHTAIDLAQQVHSPLLIHMLSVVKTERIKANS----ACLKLLNRYKVCLQSVFS---VVVVGAFGAILDMRTESWLLKGILLACIMAVINLASRQLATVA---------VRSLIPSTGLIASVFWMVVTWVLWFLPDEPSAA--VQMLFTVNITAVLYYYIRSCRTDPGHVKATEEEK--KKNIVVLAEAG--CLDPRIFCTSCMMRKPMRANHCFSCNACVAKQDHHSIWINGCIGARNHPFFVLFLVALNFLCIWMFYGSITYWS---RHCPLHYSEEGIWGALTALMGCS-----PWLLYVFCFVFFHTTWASILLVLQLYQIAF-------------------LGLTTSERANLMHRQRKLPQAVSLRQNPFNHGVVKNLVNFFQWRFCGLCKPMV--LDWTQQHPMGLGRDMFSSPDAV---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q80TN5-1", "uniprot_id": "ZDH17_MOUSE", "id": "Q80TN5-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "-MQREEGFN----TKMADGPD----EYETETGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPD---KENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ-----DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFDHS---------MHSALPLGIYLATKFWMYVTWFFWFWNDLNFLF--IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWG---LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFLWVAVLLMCQLYQITC-------------------LGITTNERMNAR-RYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVI--VDWTRQYTIEYDQISGSGYQLV---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTT0-1", "uniprot_id": "ZDH17_RAT", "id": "E9PTT0-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "---------------MADGPD----EYDTETGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHVDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPD---KENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ-----DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHS---------MHSALPLGIYLATKFWMYVTWFFWFWNDLSFLS--IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWG---LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFMWVAVLLMCQMYQITC-------------------LGITTNERMNAR-RYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVI--VDWTRQYTIEYDQISGSGYQLV---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUH5-1", "uniprot_id": "ZDH17_HUMAN", "id": "Q8IUH5-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "-MQREEGFN----TKMADGPD----EYDTEAGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPD---KENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ-----DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHS---------MHSALPLGIYLATKFWMYVTWFFWFWNDLNFLF--IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWG---LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFMWVAVLLMCQMYQISC-------------------LGITTNERMNAR-RYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVI--VDWTRQYTIEYDQISGSGYQLV---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVX9-1", "uniprot_id": "ZDH17_DANRE", "id": "A5WVX9-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "---------------MADALV----GYEKEAGCVPI---LHP----EEIKPQSHYNHGYNE--SRKSHVDDYSTWDIVKATQYGIFERCRELVEAGYDVRQPD---KENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIAKGQ-----DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEANANVDAQNIKGETPLDLAKQRKNVWMINHLQEARQAKGYDSP----SYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGVMYAVMWLVVQFLSKSFFDHS---------MHSALPLGIYLATKFWMYITWFYWFWNDLPFVT--IHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWR---IHCATSYTKDGFWIYITQIATCS-----PWMFWMFLNSVFHFMWVAVLIMCQLYQIAV-------------------LGITTNERMNAR-RYKHFKVTATSIESPFNHGCMRNLIDFFELRCCGLLRPVP--IDWTSQYTIEYDQTSGSGYQLV---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUW9-1", "uniprot_id": "HIP14_DROME", "id": "Q9VUW9-1", "name": "Palmitoyltransferase Hip14", "aln": "--------------MYQSACQ----AATTGS-CVPG---------TGQQPDNERQSALIAQQPPTAPVEPDYSGFDIVKATQYGAIARVRELVESGWDVNQPD---SETVTLLHWAAINNRRDIIRYFLEKGATVDAVGGELNATPLHWATRQGHLGAVVLLMAAGADPRIRDAEGCSCIHIAAQFAHTALVAYFIAKGV-----DPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANPAMVDYTHGNTALHWAILARNATAISTLVLKSKASLDVPNLRGETPLSMLESQTGAIWIGAKVMDRVKEAALTSQQRRSLLSKLRHDKRLRWWSMVACPFTAFYLAGIVFTVNT-LYIIKFFLLGCLYSIFHTIGKALFDEH---------LMALLPLSVYLATKAWFYVTWLMYID-DAVSFT--ATVCFLISSLLLWVCFLKSWKGDPGIIRPTREQR--FKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYV---NQCNVRF--DDFLGAMRAIGNCD-----AWVGWVMGNALLHMSWVILLTICQTYQVIC-------------------LGMTTNERMNRG-RYRHFQAKGG--HSPFTRGPIQNLVDFLECSCFGLVQPKR--VDWMNYYDYDAQTHQTIEKEPLLSVDCPDGMAGDHQYV-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39010-1", "uniprot_id": "AKR1_YEAST", "id": "P39010-1", "name": "Palmitoyltransferase AKR1", "aln": "MVNELENVPRASTLTNEEQTVDPSNNDSQEDISLGDSNEITSLASLKAIRSGNEEESGNEQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLT-VAELLKFGASIKIADTEG-FTPLHWGTVKGQPHVLK-YLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALTHSGFDYHGYP------IKKWFKKSQHAKLVTFITPFLFLGIAFALFSHINPLFVIIVLFLLAIATNKGLNKFVLPSYGRMGVHNVTLLRSPLLSGVFFGTLLWVTIVWFFKVMPRTFSDEQYTNILMLVILVSVFYLFGQLVIMDPGCLPEETDHENVRQTISNLLEIG--KFDTKNFCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDVGLKNHKAFIFFITLMESGIFTFLALCLEYFDELEDAHEDTSQKNGKCFILGASDLCSGLIYDRFVFLILLWALLQSIWVASLIFVQAFQICKGMTNTEFNVLMKESKSIGPDGLSFNENFNTTPEGFAPSIDPGEESNDTVLAPVPGSTIRKPRTCFGVCYAVTGMDQWLAVIKETIGIKDSTGHNVYSITSRIPTNYGWKRNVKDFWLTSDINAPLWRRILYPPSGSKALLNGIEVDYFKLYKLPNKDVEQGNDMV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * .* * * :*::.. : * * :: ****:**** .:: : :.:** :: .* *::****** * *:: * *: **** : * :* :*::. : : *.: : . : * * *.*: :* : . . *:. . . * :.** . : : ::: ... . *. : : . . . . : ::: : : : : :.: *. :.*. . . : . : : *** :.. .* * * * :: ** :*:*:*: .. : :*: *::. * :* ** :: :: : :: * :. : *. :: :: :: * * . * :*: *:: *. . . . . . *: . :* ", "identical_positions": 77, "similar_positions": 140, "identity": "9.94%" }, { "cls_id": "homologset.agr.SGD:S000002673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AUE5-1", "uniprot_id": "PEX10_MOUSE", "id": "B1AUE5-1", "name": "Peroxisome biogenesis factor 10", "aln": "-----------------MARAGA--PEVIRAAQKDEYYLGGLRSAAGEALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSQQRVPSRLRRAALVALHAVLPYLLDKALLPLEQELQADGDAPRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRKALQRAVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDQ----KARTSYGLLGLISLLHLVLS---MGLR-LYSFRQKQRARKEWRLHRNLSHRRSS------------------LEDRA----VCR-TPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZC81-1", "uniprot_id": "D3ZC81_RAT", "id": "D3ZC81-1", "name": "Peroxisome biogenesis factor 10", "aln": "-----------------MAQAGP--PEVIRAAQKDEYYLGGLRSAAGGALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSRQRVPSRLRRGVLVALHAVLPYLLDKALLPLEQELQAEGDGTRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRRALQRAVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDL----RACTSYRLLGLISLLHLALS---LGLQ-LYSFRQKQRARKEWRLHRNLSHRRSS------------------LEDRA----VCR-APLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60683-1", "uniprot_id": "PEX10_HUMAN", "id": "O60683-1", "name": "Peroxisome biogenesis factor 10", "aln": "-----------------MAPAAASPPEVIRAAQKDEYYRGGLRSAAGGALHSLAGARKWLEWRKEVELLSDVAYFGLTTLAGYQTLGEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAVLPYLLDKALLPLEQELQADPDSGRPLQGSLGPGGRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLACLQRLHVAWFYIHGVFYHLAKRLTGITYLRVRSLPGEDL----RARVSYRLLGVISLLHLVLS---MGLQ-LYGFRQRQRARKEWRLHRGLSHRRAS------------------LEERA----VSR-NPLCTLCLEERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLRHYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0D7-1", "uniprot_id": "Q9W0D7_DROME", "id": "Q9W0D7-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------MDFRNARARQPEIVRSVQKDARYTNELAEDLSDVLR-LTGPRNWIKYNQMCRLLAELSYHGFASANNLQTLGEEYTGIIQVDGNYKQIPSRLLQLIAIVLEFGGDSLFQRLMQKLDTYVANNDE-----------------------------IRTEIKPQLKKIIQRLRQSPSYVKALHKSLFYLDASKYQLSKRTTGINYVLIRHWLQPEF----SLYG-YKILGVITFLQVSVS---LAISGWDAWREHKRQQLESIKQAGKNFLQRS------------------SSTKD----VDPNTPQCILCLEPRSDSSLTPCGHIFCWSCLLEWLEERDECPLCRESLKKSQVILLQNYA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05568-1", "uniprot_id": "PEX10_YEAST", "id": "Q05568-1", "name": "Peroxisome biogenesis factor 10", "aln": "MKNDNKLQKEALMRLSQLRFPFADAPSIVQAHQKDEQIQGLLIMKVTELCKLIKSQLFVNSYPKELSIFAKLLYLLFTTGRRGRTLGEEYVDLTYTNRKGTRLAGRLKMIVFAFAYPLCPYFITKLYKKIMKNNK-----------------------------------ESKIEDTESVAAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGMRYVFKHILSKNEANFREEGSQKYKVLGYILLAQNVMKWYPVLTSTLGSWIYGRKRTNDSITRSSVGLQERSEHESIEGIPKESQLTHINLSDKNQLPFIPEASRKCILCLMNMSDPSCAPCGHLFCWSCLMSWCKERPECPLCRQHCQPQEILVLRQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *.:::: *** . * : : . .: : :::.: * ::: :******..: .: . ::.. * :: : : . : : :* : **:.. * ::** *: *: : : * :** * : : :. : .: :: : : . . . * . : : * *** ..: :****:***.*: * . : ******: .::: *:: ", "identical_positions": 46, "similar_positions": 86, "identity": "12.3%" }, { "cls_id": "homologset.agr.SGD:S000002674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR64-1", "uniprot_id": "D3ZR64_RAT", "id": "D3ZR64-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------MAAAGAEGRR--AALEAVAA--PERGG---------------------------GSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFAMIPIHQLQ--HEKKYDIYFADGKVFALYRQLLQHECPR--CPHLPPFSLFGDLEQHMRKQHELFCCKLCLKHLKIFTHERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCD-ERYLDNDELLKHLRRDHYFCHFCDAD--GAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHKTACHSR--SRAEARQNRQIDLQFSFAPR------HSRRSEGVVSGEDYEEVDRYNRQGRAGRASGRGAQQNRRGSWRYKREEEDREVAAAIRASVAAQQQEETQRVEDREEGSRPKKEEAAVRVPEESRGHRRLPRAQGEGTGSKETSTNGPVSQEAFSATGPGP--VVAPSNTLPPPNPKLKDEDFPSLCVSTS--CCTAVTPSSVGLALAYPAPPRGKNTFQEEDFPALVSSAPKPSSAPSSLISAWNSSCSKKGNPP----------TPGAQAVVGSSQPSRKAG------KGSRGGRK---------------GGP-APVDE-DSGGLTVQELRSVPTTVAVSSLLAPVANQNSAKVGKKKKMGSEKPGATSSPLLPPDHTPKPSGAEQVPEAP-----LSKAEVP--VTIVVNGHSEGSALAWSIPKEPPGLP---RPLGPLPCPIPQEDFPALGGPCPPRMPPPPGFSTVVLLKG--TPPPPPPPPGLVPPISKPPPGFSSFLPSSHSTCVPSTTTITTTTTNMKAPRLAPTAGAYLVPENFRERNLQLIQSIKDFLQSDEACFSKFKSHSGEFRQGMISAAQYYKSCRDLLGENFQKIFSELLALLPDTAKQQELLSAHTDFCSRERPPS-SKSKKNKKNVWQT---STQQLGLDCCVCPTCQQVLAHGDVSSHQALHAARDDDFPSLQAIARIIT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YR4-1", "uniprot_id": "ZN598_MOUSE", "id": "Q80YR4-1", "name": "E3 ubiquitin-protein ligase ZNF598", "aln": "-------MAAAAGAEGRR--AALEAVAA--PERGG---------------------------GSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFALIPIHQLQ--HEKKYDIYFADGKVFALYRQLLQHECPR--CPHLPPFSLFGDLEQHMRKQHELFCCKLCLKHLKIFTYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCD-ERYLDNDELLKHLRRDHYFCHFCDSD--GAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHKTACHSR--SRAEARQNRQIDLQFSFAPR------HSRRSEGVVSGEDYEEVDRYNRQGRAGRASGRGAQQNRRGSWRYKREEEDREVAAAIRASVAAQQQEETQRVEDREEGSRPKKEEAAARVPEEPRGHRRLPRAQGEGSGSKEASANGPVSQEAFPATGPGP--VVALSNTLPPPSPELKEEDFPSLCASTSS-CCTAVTPGSVGLALAYPGPPRGKNTFQEEDFPALVSSAPKPSSAPSSLISAWNSGCSKKGNLP----------TPGSQAVVGGSQPPRKAG------KGSRGGRK---------------GGP-APVDEEDSGGLTVQGLRSVPTTVAVSSLLAPATNQSSAKVGKKKKVGSEKPGATSSPLLPPDHTPKPSGAEQVLEAP-----LSKAEVP--VTIVVNGHSEGSALVRSAPKEPPGLP---RPLGPLPCPIPQEDFPALGGPCPPRMPPPPGFSTVVLLKG--TPPPPPPPPGLVPPISKPPPGFSSLLPSSHSACAPSPTTTTTTTTTTKTPGLAPTPQAYLVPENFRERNLQLIQSIKDFLQSDEACFSKFKSHSGEFRQGMISAAQYYKSCRDLLGESFQKIFSELLALLPDTAKQQELLSAHTDFCSREKPPN-SRSKRNKKNVWQT---STQQLGLDCCVCPTCQQVLAHGDVSSHQALHAARDDDFPSLQAIARIIT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UK7-1", "uniprot_id": "ZN598_HUMAN", "id": "Q86UK7-1", "name": "E3 ubiquitin-protein ligase ZNF598", "aln": "-------MAAAGGAEGRR--AALEAAAAAAPERGG---------------------------GSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFATIPIHQLQ--HEKKYDIYFADGKVYALYRQLLQHECPR--CPELPPFSLFGDLEQHMRRQHELFCCRLCLQHLQIFTYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCD-ERYLDNDELLKHLRRDHYFCHFCDSD--GAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHRTACHSR--SRAEARQNRHIDLQFSYAPR------HSRRNEGVVGGEDYEEVDRYSRQGRVARAGTRGAQQSRRGSWRYKREEEDREVAAAVRASVAAQQQEEARRSEDQEEGGRPKKEEAAARGPEDPRGPRRSPRTQGEGPGPKETSTNGPVSQEAFSVTGPAAPGCVGVPGALPPPSPKLKDEDFPSLSASTSSSCSTAATPGPVGLALPYAIPARGRSAFQEEDFPALVSSVPKPGTAPTSLVSAWNSSSSSKKVAQ----------PPLSAQATGSGQPTRKAG------KGSRGGRK---------------GGPPFTQEEEEDGGPALQELLSTRPTGSVSSTLGLASIQ-PSKVGKKKKVGSEKPGTT---LPQPPPATCPPGALQAPEAP-----ASRAEGP--VAVVVNGHTEGPAPARSAPKEPPGLP---RPLGSFPCPTPQEDFPALGGPCPPRMPPPPGFSAVVLLKG--TPPPPPP--GLVPPISKPPPGFSGLLPSPHPACVPSPATTTTT----KAPRLLPAPRAYLVPENFRERNLQLIQSIRDFLQSDEARFSEFKSHSGEFRQGLISAAQYYKSCRDLLGENFQKVFNELLVLLPDTAKQQELLSAHTDFCNREKPLS-TKSKKNKKSAWQA---TTQQAGLDCRVCPTCQQVLAHGDASSHQALHAARDDDFPSLQAIARIIT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFK1-1", "uniprot_id": "ZN598_DANRE", "id": "Q6PFK1-1", "name": "E3 ubiquitin-protein ligase ZNF598", "aln": "-----MHCAERLRTEERASPGLIACTAVHKPSKSTRIKPTKPHHTPSN---SMESALKKDTESTCVLCCQDIDLFAVGKCDHPVCYRCSTKMRVLCEQKYCAVCREQLDKVVFLRKPEAFATLNIHHYQ--CEKKYDIYFGDGKVHAQFRKILLNECPH--CPEPKVFSKFEELEQHMRKQHELFCCKLCLKHLKIFSYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCD-DRYLDNDELLKHLRRDHYFCHFCDAD--GAQEYYSDYQYLSEHFRESHYLCEEGRCSTEQFTHAFRTEIDYKAHKAAAHSK--NRAEARQNRQIDIQFNYAPR------QQRRND--VGGDDYEEVDRFNRQGRPGRGRGPGGQQNLR-SWRYNREEEDREMAAAMRASMASHQEERSHAQE--RSMLKPRREEKLE--PDETRNNRSTARPTN-DTQARSMKSNGSLAGQDFPVLGAGAP-PAPVQSMIQKPSVSLKEDDFPSLSGSVVS---SPMTP-------AYTNQPRKHSSFQEEDFPALVS-KIKPLKPQSSAASAWSQAGSKPVVAPNKPVVLPTKMTPMSSSSILSSTDPLPSASVPQPLTASSSRRKKMLTLTESHKDPPKIRCPSSSDDEDPHSGKTAQEIRTVPTMLDISTLLTVKGSSPQANPKASKKKKQTTASSLGSPSHTPETVSKMAHKENVPEKKPPETGLNKAPTAPKTNSIVNGVAEKPAEALSCTSFPENITSSKQPVTDQAPPSKEEEFPALIS-----KKPPPGFKSAFPLRNSQSALPPPPPPGLGPAVSKPPPGFTGVPLNSN---VEDSSVSAVN-------RPTPAIGSYLIPDHFQQRNMDLIQSIKNFLQNDETKFNEFKNYSGQFRQGALPAVQYYKSCQELLGENFNRVFNELLVLLPDTRKQQELLTAHGDFKALEKQQQGSKPKKSKKKAWQTGTSSSSSLDLDCQVCPTCKQVLALKDFNTHKTLHIG-DDDFPSLQAISKIIS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W149-1", "uniprot_id": "Q9W149_DROME", "id": "Q9W149-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MQNGKPRSSARPSFHRRPKDGVANTTTDNAAVKPEALESYTG-----------------NDDNACVVCFKNVEIFSIGDCDHPVCYECSTRMRVLCQQNECPICRHVLSKVLFTLDKLPYRELEANNRSDLYSKKYRIGFCTAEIRQQFFKLLDHPCPK--CDAP-PYRTFEGLRNHVRSEHKLLYCDLCVETLNIFTFERRCYTQAELQLHNTKGDPDNRSHRGHPLCEYCN-KRYVDRDELFRHLRREHYFCHFCDAD--GCNEFYNDYADLAEHFRAEHFLCEEGKCATEQFVGAFRNEIEYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLARTKENFPALGGGNGGGVTGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVSNRSAAVPKKAATPQVDFPALPGKGNK------------------------KNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASPS----------TFQKLQMVQKEEDEAKAR--------QEALKK---------------SAPKLTAAEFPSLGPSASASSSRTTAPKPSSGSPSLNWSKPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQE----------------QQANKKDKKQKDKKSNQEN--------QPKTAKPKERNNNNEQKTNGAPSTPIRAPPGLKPGGPLKP--------------------PPGFVSNVTVNSVAKLPNNLTFTNSLG--ESYDIVPSPYTYTDPPDTEVRNQKLVDEVMSLLKTPEALN-EFRLLSSKFRDGSCSGQAYYEHCQCAMLSSFYNLFPELLAMLPDISKQQELYLVHKQHLNSLPPAE-------------------RKSVPALEVCKVCKQILITADLKSHQQAHEL-TKNFPVLGSSASNTHRN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05580-1", "uniprot_id": "HEL2_YEAST", "id": "Q05580-1", "name": "E3 ubiquitin-protein ligase HEL2", "aln": "-MSESVKENVTPTRNFRRTQGPQNNTKPHNDRKNFRRKQKKNNLSAEPNLTTSSADDTDEENELCVICARKLTYVSLTPCHHKTCHICGFRQRALYNKKSCLICRTENEEVMFTDRIDGDISDKYNFCE--KNEKYGINFTSEEVATETLNLLKFFCPLSKDEQVCDFGSFKKYNEHLKSEHNRMICLICATHKHAFPCELEIFTQNQLRNHQTKGNSE--GFKGHPMCAFCSGKRFYSDDELYIHMRNQHEKCHICDKMNPASPQYFKDYNQLFDHFKHSHYVCTVQTCLDNKFV-VFKDELELQAHILQEHGN-ILKGKPKFFQSELSTFISAPS------------------------------------------------RVIRERDDYDLPSISSLPGSSSGSRTDVRSASSPEESRLRLAERAKYYLENSKEDFNKFSSYNEDYSKGRLSAEKLLESYKLLFTKPNADVYLLIHNLAET---------FPK-------------------------------NSSKYNNLNAIYEQREQTLARQTSLPSLSSDSSLSMSIGR---------------GHWGGTNDGGSAG-----------------------------------------AALGVRNIKNLPTLKSPSASYDPFATTVKKNTLRPVQNIKRTTPQSVSYRTSTNTVAFSPTYLESKKGS--------------SSTSLNNSKDKLKSLN---------------LPQLPPPKPKVQIPGLNRP------------------------------------------------------------------------------QIADPKQWGKKSSTQDTNVHDNLR-------ELNTTSGGNKK---------------------------------KGKQKQLLFHIGV-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . : **:* .: :: *.* .*: *. : *.* ::. * :** :*:* : . .:** * * :: ::* ** : * .:*:: :*: : * :* : *. * . ::: :* *. :*:.: ..:***:* :*. .*: . *** *:*.:* **:** .. :::.** * :**: .*::* * ::*. .*: *:: :** *.. : :.: : : .* * . .: . .. . :. . ** . : : : . . :: . . : . . . *: : : . .. . . : * . . : : * . :. .: . *: ::. *. :. **::* ", "identical_positions": 74, "similar_positions": 143, "identity": "7.3%" }, { "cls_id": "homologset.agr.SGD:S000002675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M7T1-1", "uniprot_id": "CIAO1_RAT", "id": "Q5M7T1-1", "name": "Probable cytosolic iron-sulfur protein assembly protein CIAO1", "aln": "MKDALVLQSRVPAHPDSRCWFLAWNPTGTLLASCGGDRKIRIWGTEGDSWICKSVLSEG-HQRTVRKVAWSPCGNYLASASFDATTCIWKKNQD-----DFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE-DEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYQEE--GDDWVCCATLEGHESTVWSIAFDPSG--QRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCVCTLSGFHTRTIYDVAWCQLTGALATACGDDAIRVFEEDPGSDPQQPTFSLTAHLRQAHSQDVNCVAWNPKE-AGLLASCSDDGEVAFWEYHQPAGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KN2-1", "uniprot_id": "CIAO1_MOUSE", "id": "Q99KN2-1", "name": "Probable cytosolic iron-sulfur protein assembly protein CIAO1", "aln": "MKDSLVLQSRVPAHPDSRCWFLAWNPSGTLLASCGGDRKIRIWGTEGDSWICKSVLSEG-HQRTVRKVAWSPCGNYLASASFDATTCIWKKNQD-----DFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE-DEYECVSVLSSHTQDVKHVVWHPSQELLASASYDDTVKLYQEE--GDDWVCCATLEGHESTVWSIAFDPSG--QRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHTRTIYDVAWCQLTGALATACGDDAIRVFEEDPGSDPQQPTFSLTAHLRQAHSQDVNCVAWNPKE-PGLLASCSDDGEVAFWEYHQPAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76071-1", "uniprot_id": "CIAO1_HUMAN", "id": "O76071-1", "name": "Probable cytosolic iron-sulfur protein assembly protein CIAO1", "aln": "MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEG-HQRTVRKVAWSPCGNYLASASFDATTCIWKKNQD-----DFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE-DEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREE--EDDWVCCATLEGHESTVWSLAFDPSG--QRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKE-PGLLASCSDDGEVAFWKYQRPEGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0D9-1", "uniprot_id": "CIAO1_DANRE", "id": "Q6P0D9-1", "name": "Probable cytosolic iron-sulfur protein assembly protein ciao1", "aln": "MKGALELQHRVSAHPDSRCWYVAWNPAGTTLATCGGDRAIRIWGKEGDSWECKCVLSDG-HQRTVRKVAWSPCGKYLASASFDATTCIWKKTDE-----DFECLTVLEGHENEVKCVAWAPSGSLLATCSRDKSVWIWEVDEE-DEYECLSVVNSHTQDVKHVVWHPTQELLASASYDNKICIYKEE--DDDWECRATLEGHESTVWSLTFDPEG--RRLASCSDDRTVKIWKESTTGD------GSSDESWKCICTLSGFHGRTIYDIAWCRLTGALATACGDDGVRVFSEDPTADPEQPIFALSAHVPKAHNQDVNCVSWNPKE-AGLLATCSDNGEFAIWKYNSA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K1Y4-1", "uniprot_id": "CIAO1_DROME", "id": "Q7K1Y4-1", "name": "Probable cytosolic iron-sulfur protein assembly protein Ciao1", "aln": "-MGRLILEHTLQGHKG-RIWGVAWHPKGNVFASCGEDKAIRIWSLTGNTWSTKTILSDG-HKRTIREIRWSPCGQYLASASFDATTAIWSKSSG-----EFECNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAGD-DEFECAAVLNPHTQDVKRVVWHPTKDILASASYDNTIKMFAEEPIDNDWDCTATLTSHTSTVWGIDFDADG--ERLVSCSDDTTIKIWRAYHPGNTAGVATPDQQTVWKCVCTVSGQHSRAIYDVSWCKLTGLIATACGDDGIRIFKESSDSKPDEPTFEQITAEEGAHDQDVNSVQWNPVV-AGQLISCSDDGTIKIWKVTE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05583-1", "uniprot_id": "CIAO1_YEAST", "id": "Q05583-1", "name": "Cytosolic iron-sulfur protein assembly protein 1", "aln": "-MASINLIKSLKLYKE-KIWSFDFSQG--ILATGSTDRKIKLVSVKYDDFTLIDVLDETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDY--DDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRVWKYMGDDE-------DDQQEWVCEAILPDVHKRQVYNVAWG-FNGLIASVGADGVLAVYEEVDG---EWKVFAKRALCHGVY--EINVVKWLELNGKTILATGGDDGIVNFWSLEKAA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : * . : :*: . *: *:: . : : :*.: *::::*.: * * . **:.***:*..** * . ::: : :******** *:*: .* ***********:**. . :*:** :*:. *:****:*:***:: :***:***:.: :: : :** * *.* .* .***. ** ** * *** *:::*: .: ..: * * . :.. * * :*:::* :.* :*:. .*. : ::.* : * : .: ::* * * * : .*:* . :*. ", "identical_positions": 99, "similar_positions": 105, "identity": "28.21%" }, { "cls_id": "homologset.agr.SGD:S000002676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2U4-1", "uniprot_id": "A0ABK0M2U4_RAT", "id": "A0ABK0M2U4-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "---------------------MALFSVRKARECWRFIRALHKG-----------------------------PTATAAPQKESGERVFSGIQPTGIPHLGNYLGAIESWVKLQEEYD---TVIYSIVDLHSITVPQ-DPGILQQSILDMTAVLLACGIDPERSILFQQSQVSEHTQLSWILTCMVRLPRLQHLHQWKAKAARQKHD-------------GTVGLLTYPVLQAADILCYKSTHVPVGEDQVQHMELVQDLARSFNQKYG-ELFPLPRSILTS--MKKVKSLRDPSAKMSKSDPDKLATVQITDSPEEIVRKFRKAVTDFTSE-VTYEPDSRPGVSNMVAIHAAVSGLSVEEVVRNSAGVDTAR-YKLLVADAVIEKFAPIRSEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYK1-1", "uniprot_id": "SYWM_MOUSE", "id": "Q9CYK1-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "---------------------MALFSVRKARECWRFIRALHKG-----------------------------PAATLAPQKESGERVFSGIQPTGILHLGNYLGAIESWVNLQEEYD---TVIYSIVDLHSITVPQ-DPTVLQQSILDMTAVLLACGINPEKSILFQQSKVSEHTQLSWILTCMVRLPRLQHLHQWKAKAAKQKHD-------------GTVGLLTYPVLQAADILCYKSTHVPVGEDQVQHMELVQDLARSFNQKYG-EFFPLPKSILTS--MKKVKSLRDPSSKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSE-VTYEPDSRAGVSNMVAIHAAVSGLSVEEVVRSSAGLDTAR-YKLLVADAVIEKFAPIRKEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGM6-1", "uniprot_id": "SYWM_HUMAN", "id": "Q9UGM6-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "---------------------MALHSMRKARERWSFIRALHKG-----------------------------SAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWVRLQDEYD---SVLYSIVDLHSITVPQ-DPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQKHD-------------GTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQGFNKKYG-EFFPVPESILTS--MKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSE-VTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTAR-YKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GDY4-1", "uniprot_id": "A0AC58GDY4_DANRE", "id": "A0AC58GDY4-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "MITQLTHDEGEDVFTKRRVFLIRQQTFATACHTWMFEVDSPKTGYSLKPSRAEPGQYLDGRPHGTTEVVSVRPAEDAQPESRSKGLVFSGIQPTGIPHLGNYLGALESWVALQDDYS---TVMYSIVDLHSITQPQ-DPQVLRDNIMDMAASLLACGIDPTRSILFQQSQVSEHAELSWILGCLTSMPRLRHLPQWKMKS-KQKNE-------------GSVGLYTYPVLQAADILLYKSTHVPVGEDQIQHLELAQDLARIFNNQYG-EFFPEPRALLSG--TRKVKSLRDPSSKMSKSDPQRFSAVFLTDTPDDIALKIRRAVTDFTSE-VTYEPDTRPGVSNLVSMHAAVSGQTIEGVIRLAEGMDTGQ-YKNMVAEAIIKKLQPIRLEIQRLRADQGYLESLLAQGAEKARSLAAPVMKEVRKLLGFY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVL8-1", "uniprot_id": "Q9VVL8_DROME", "id": "Q9VVL8-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "MFRFGKLHRSLSKVAKKG--QTAVYSQRRCIQARSFLPGLASRTAG---TPSATAQVTGGNKQHVHPHGNSVNSGHEEHNTRWPRKVFSGIQPTGSLHLGNYLGAVRKWVQLQNARD---DVTVCIVDLHSITMPH-NPPLLRENIFTMAATLLACGIDPTKSTLFVQSAVAEHAEFNWILSSLTTMPRLAQLPQFREKS-RLLKD-------------VPLGLYVYPVLQAADIMLYKSTHVPVGADQIQHIQLAQHLARIYNGRYG-ETFPVCTAIIEDGDASRVLSLRDPSKKMSKSEANPKATINLCDSPDLITQKIKKAVTDFTSD-ITYNPGKRAGVSNLVNIHAQVTGQSIKTVVNEAATLDTAK-YKDRVAEAVVEHLRPIREQIHHHMTKRNEMIYLLEVGAEKARQQARQTLNDVKQRLGLGTSANIPAAVHVAPLLPAPDISKTSASRRMSKDFDGNVHERHERMYGFGDQPSGGAGQSATGEVADMPQAVVPRVIRRAPIVPTQSMRVEKQLGSTRTRHVFQMDTCNAPHIGFKPPPGFSASMVTGALAKNKRATVKPVTGNLGFGQQSQGGSYKHSQNVNPSAVSTIAREVNAAKKQEFTCNPALYGSALESLSNSSRSSEKTNSTAGDSEFIIVASEEEEQAASSEEQREEAEEEESGEREREKGERNATEATKVEI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04803-1", "uniprot_id": "SYWM_YEAST", "id": "P04803-1", "name": "Tryptophan--tRNA ligase, mitochondrial", "aln": "---------------------MSNKQAVLKLISKRWISTVQRA-----------------------------DFKLNSEALHSNATVFSMIQPTGCFHLGNYLGATRVWTDLCELKQPGQELIFGVADLHAITVPKPDGEMFRKFRHEAVASILAVGVDPEKASVIYQSAIPQHSELHWLLSTLASMGLLNRMTQWKSKSNIKQSTNGDYLVNDSDVGKVRLGLFSYPVLQAADILLYKSTHVPVGDDQSQHLELTRHLAEKFNKMYKKNFFPKPVTMLAQ--TKKVLSLSTPEKKMSKSDPNHDSVIFLNDEPKAIQKKIRKALTDSISDRFYYDPVERPGVSNLINIVSGIQRKSIEDVVEDVSRFNNYRDFKDYVSEVIIEELKGPRTEFEKYINEPTYLHSVVESGMRKAREKAAKNLADIHKIMGF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** ***** ******** . *. * : . : :.***:** *: : :::. .* :** *::* :: :: ** :.:*::: *:* :. : * :: *:: *: :** *********: ********* ** **::*.:.**. :* * : ** ::: :* ** *. *****:.: :.: : * *. * *:::*:** *: . *:* *.****:: : : : ::: *:. .:. : :* *::.:::.: : ::.: . : :: * **:. * :::: :*: ", "identical_positions": 100, "similar_positions": 109, "identity": "14.47%" }, { "cls_id": "homologset.agr.SGD:S000002678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64430-1", "uniprot_id": "ATP7A_MOUSE", "id": "Q64430-1", "name": "Copper-transporting ATPase 1", "aln": "MEPSVDANSITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALLHNANPLPVLTNTVFLTVTAPLTLPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKNTPVK--------SSEGSQQKSPSYPSDSTTMFTIEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIEAISPGQYRVSIASEVESTASSPSSSS--LQKMPLNIVSQPLTQEAVININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALP-DMKEP--------------LVVIAQPSL---ETPLLPSSNEL-ENVMTSVQN--------KCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGAMVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGSLGFEASLVK-KDRSAN--HLDHKREIKQWRGSFLVSLFFCIPVMGLMVYMMVMDHHLATLHHNQNMSNEEMINMHSAMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMFERAKV--NPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESN-KISRNKILAIVGTAESNSEHPLGAAVTKYCKKELDT------ETLGTCTDFQVVPGCGISCKVTNIEGLLH-------------------KSNLKIEENNIKNASLVQIDAINEQSSTSSSMIIDAHLSNAV---------NTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGIT--KVFAEVLPSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIR------NDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPT-----YDNYELHPRSHTGQRS---PSEISVHVGIDDTSRNS------PRLGLLDRIVNYSRASINSLLSDKRSLN-SVVTSEPDKHSLLVGDFREDDDTTL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70705-1", "uniprot_id": "ATP7A_RAT", "id": "P70705-1", "name": "Copper-transporting ATPase 1", "aln": "MEPNMDANSITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATVIYNPKLQTPKTLQEAIDDMGFDALLHNANPLPVLTNTVFLTVTAPLALPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSANQIVELVPDLSLDMGTQEKKSGTSEEHSTPQAGEVLLKMRVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKSTPVK--------SSEGSQQKSPAYPSDSAITFTIDGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEILRKAIEAVSPGQYRVSISSEVESPTSSPSSSS--LQKMPLNLVSQPLTQEVVININGMTCNSCVQSIEGVISKKPGVKSIHVSLTNSTGTIEYDPLLTSPEPLREAIEDMGFDAVLPADMKEP--------------LVVIAQPSL---ETPLLPSTTEP-ENVMTPVQN--------KCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAELIRELGFGAVVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGNLGFEASLVK-KDRSAN--HLDHKREIKQWRGSFLVSLFFCIPVMGLMIYMMVMDHHLATLNHNQNMSNEEMINMHSSMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALRHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKV--NPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVEAYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESN-KISRNKILAIVGTAESNSEHPLGAAVTKYCKQELDT------ETLGTCTDFQVVPGCGISCKVTNIEGLLH-------------------KSNLKIEENNIKNASLVQIDAINEQSSPSSSMIIDAHLSNAV---------NTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGIT--KVFAEVLPSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMASVGIAIGTGTDVAIEAADVVLIR------NDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFLPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPT-----YDNYELRPRSHTGQRS---PSEISVHVGIDDTSRNS------PRLGLLDRIVNYSRASINSLLSDKRSLN-SVVTSEPDKHSLLVGDFREDDDTTL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04656-1", "uniprot_id": "ATP7A_HUMAN", "id": "Q04656-1", "name": "Copper-transporting ATPase 1", "aln": "MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVK--------SSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSSSS--LQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLS-DTNEP--------------LVVIAQPSS---EMPLLTSTNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVK-KDRSAS--HLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKV--NPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN-RISHHKILAIVGTAESNSEHPLGTAITKYCKQELDT------ETLGTCIDFQVVPGCGISCKVTNIEGLLH-------------------KNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNAL---------NAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT--KVFAEVLPSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIR------NDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPT-----YESYELPARSQIGQKS---PSEISVHVGIDDTSRNS------PKLGLLDRIVNYSRASINSLLSDKRSLN-SVVTSEPDKHSLLVGDFREDDDTAL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QEG1-1", "uniprot_id": "F1QEG1_DANRE", "id": "F1QEG1-1", "name": "P-type Cu(+) transporter", "aln": "MALSTNLCRVTLGVEGMTCGSCVQSIEGRIGGLPGVIHIQVSLEQNNATVTYDHTQHTPQSIADAIEDMGFESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPKEGSTSRSFSGVEAVKMRIEGMVCLSCTTTIEGKIGKLKGVEKIKVSLESQEAAVVYLPYIITVDEIVKQIEVAGFKATVKSKPRQLKLSASEVERLLSAPKQ--------TEEKLSE--PPADSTVTTLFQVTGMHCNSCVVNIQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPG------------------FLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFLPETNSLV--------------PSVVKSPSLSVRSSSLSPVRSAVKENEAESDAEPSTN-TISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTATVMDNYDGSDGSLELVVRGMTCASCVHKIESNLMKQKGILYASVALSTNKAHIKYDPEVTGPRDIIRLIENMGFTASLVK-KDRPGS--HLDHSREIRQWKRSFQISLFFCVPVMGMMIYMIVVDHMIDKYHQHHNATAEDRAKYHSTMFLEKQLLPGLSIMNLISFLFCVPVQFIGGRYFYCQAYKAVKHRTANMDVLIVLATTIAFTYSVVVLLVAMVERAKV--NPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLNEDMSVLSEEQVDVELVQRGDVVKVVPGGKFPVDGRVIEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLIKATHVGTDTTLSQIVKLVEEAQTSKAPIQQFADKISSYFVPFIVVISVLTLLAWIIIGFVNFSLVQTYFPGYDKSISEAEAVIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIQSVVFDKTGTITYGAPKVVQVKMLAEGN-RLPRSKLLAIVGTAENSSEHPLGAAITKYCKQELGT------ESLGTCTDFQAVPGCGIRCLVSNTENLLK-------------------REDSDSEEN-QHNAVLIQISDARAHS-TEHPLIMDPQPLTVV---------QTASYTVLIGNREWMRRNALQVRADVDEAMTEHERRGCTAVLVAVDNELCAMVAIADTVKPEAELAVHVLSAMGLEVVLMTGDNSKTARAIAAQVGIR--KVFAEVLPSHKVAKVEQLQQE--GKRVAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIR------NDLLDVVGSIDLSKKTVKRIRINFVFALMYNLVGIPIAAGVFMPVGLVLQPWMGSAAMALSSVSVVLSSLLLKCYTKPT-----VEKLKRRLGDVRTHGS---LSDVSVHIGMGELRRPS------PKLSLLDRFVNYSRASINSLRSDKHSMN-SMALSEPDKHSLLVGDDHCDNEIV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q64446-1", "uniprot_id": "ATP7B_MOUSE", "id": "Q64446-1", "name": "Copper-transporting ATPase 2", "aln": "-------------MDPRKNLASVGTMPEQERQVTAKE-ASRKILSKLALPGRPWEQSMKQSF--AFDNVGYEGGLDSTSSSPAATD-VVNILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQ-EAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRIKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDVNKLESTNLKKETVSPVQISNHFETLGHQGSYLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQIQYDPSCVTPMFLQTAIEALPPGHFKVSLPDGVE---ENE-----PQSGSSQRHQEQGPGRTAVLTISGITCASSVQPIEDMLSQRKGVQQTSISLAEGTGAVLYDPSIVSLDELRTAVEDMGFEVSVNSETFTINPVRNFKSGNSVPQTMGDIAGSVQKMAPDTRGLPTHQGPGHSSETPSSPGATASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQ-RNPNAH--HLDHKTEIKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQET-----------------MVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAYKSLRHRSANMDVLIVLATTIAYAYSLVILVVAVAEKAEK--SPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLADVA-TLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGT------ETLGYSTDFQAVPGCGISCKVSNVEGILA-------------------RSD-----LTAHPVGVGNPP-----------------TGEGA---------GPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGVDVALITGDNRKTARAIATQVGIN--KVFAEVLPSHKVAKVQELQNE--GKKVAMVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIR------NDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPD-----LERYEAQAHGRMKPLS---ASQVSVHIGMDDRRRDS------PRATAWDQVSYVSQVSLSSLTSDRLSRHGGAAEDGGDKWSLLLSDRDEEQCI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64535-1", "uniprot_id": "ATP7B_RAT", "id": "Q64535-1", "name": "Copper-transporting ATPase 2", "aln": "-------------------------MPEQERKVTAKE-ASRKILSKLALPTRPWGQSMKQSF--AFDNVGYEGGLDSTCFILQLTTGVVSILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQ-EAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINKLESTNLKRAAVPPIQNSNHLETPGHQQNHLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYDSSCITPLFLQTAIEALPPGYFKVSLPDGLE---KESGSSSVPSLGSSQRQQEPGPCRTAVLTITGIPRDSSVQPMEDMLSQMKGVQQIDISLAEGTGAVLYDPSVVSSDELRTAVEDMGFEVSVNPENITTNRVS---SGNSVPQAVGDSPGSVQNMASDTRGLLTHQGPGYLSDSPPSPGGTASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEVIQSPRIAQLIEDLGFEAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIGFHASLAH-RNPNAH--HLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHET-----------------MVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAYKSLRHKSANMDVLIVLATTIAYAYSLVILVVAIAEKAEK--SPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLVDVA-TLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGT------ETLGYSTDFQAVPGCGISCKVSNVESILA-------------------HRG-----PTAHPIGVGNPP-----------------IGEGT---------GPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALASITLKSMGVDVALITGDNRKTARAIATQVGIN--KVFAEVLPSHKVAKVQELQNK--GKKVAMVGDGVNDSPALAQADVGIAIGTGTDVAIDAADVVLIR------NDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMG--SAAASSVSVVLSSLQLKCYRKPD-----LERYEAQAHGRMKPLS---ASQVSVHVGMDDRRRDS------PRATPWDQVSYVSQVSLSSLTSDRLSRHGGMAEDGGDKWSLLLSDRDEEQCI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35670-1", "uniprot_id": "ATP7B_HUMAN", "id": "P35670-1", "name": "Copper-transporting ATPase 2", "aln": "-------------------------MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSF--AFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQ-EAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQ-RNPNAH--HLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQS-----------------MVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAER--SPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVA-TLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGT------ETLGYCTDFQAVPGCGIGCKVSNVEGILA-------------------HSERPLSAPASHLNEAGSLP-----------------AEKDA---------VPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGIN--KVFAEVLPSHKVAKVQELQNK--GKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIR------NDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPD-----LERYEAQAHGHMKPLT---ASQVSVHIGMDDRWRDS------PRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T720-1", "uniprot_id": "A0A8N7T720_DANRE", "id": "A0A8N7T720-1", "name": "Copper-transporting ATPase 2", "aln": "-------------------------------------------MNKLSPFSN-LAKFISKSP--DNGPVGGE---------QLCMKDCKPLCHCDPELCVCSLPQ--NSKDGPTEYK---ENGSQQEGWIP-------TKHAFDNFGYEPDGLKHNLV----HQLPSE-EGMVKIQVEGMTCQSCVRSIEEQIGRLEGVIGVQVSLSDKEAILRFNPAKVTPEDMRKRIEDMGFDALILALQG--QIQPLSTDWSEVT------------------------------LGVEGMHCGSCVKNITETLSGMLGVNSVFVSLEKGSVDLRFDPSLLTLETVKGFLEEIPPGNFRVSIPG-----------------WSSRLNSASTPTQSVTIGIEGMTCNSCVQAIEGMMSQRAGVCSIKVYLQEKKGIVTFDSTVTCPEELRAEIEDMGFEAWLNQD-----------SEICEVSSVSQMPSGLKHLPSQRHPSKPSPSP-ITKENADGTGERELRKCFVHVTGMTCASCVSNIERNLVKHEGIKSVLVALMAGKAEVKYDPGLLDPAQIVQLISHLGFGASVMEEHSVQDGVLDLSVTGMTCASCVHNIESKLLRTKGIQEASVALATNKAHVKFDSDLVGSRDIVRIIEGLGFGVSLIK-NEGLNN--TLDHQEEIRQWKHSFLFSLVFGIPVMGLMIYMMVMDSQHKEHGG--------------SMPADQNILPGLSIINLAFFLLCTPVQFLGGRYFYIQAYRSLRHGVANMDVLIVLATTIAYVYSFTVLIVAMIEGAKQ--SPLTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATDATIVSLGPDNTIIREEQVSVDLVQRGDVVKVAPGGKFPVDGKVIEGTSMADESLITGEPMPVIKKAGSCVIAGSINAHGALLVEATHVGSETTLSQIVKLVEEAQTSKAPIQQLADKLSGYFVPFIVVISILTVTAWLIIGFLDFDVVSKNFPGYNQNISRTEVIVRFAFQASITVLSIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVGAVMFDKTGTITNGVPQVTRVLVLWDRA-RLPLRTVLAVVGTAEASSEHPLGMAVAKHCKEELGA------ETLGFCHDFQAVPGCGISCKVSSVEDLLQ-------------------NSPKTQETKASAVKQTPLLVTLQGVTTDESSLVAD--TDSGS---------DSPSYSVLIGNRQWMLRNGLEVTADVDNAMSSHETKGQTAILVAIDGVLCAMIAVADTVKAESALAVHTLSSMGIEVYMITGDNRRTARAIATQVGIR--KVFAEVLPSHKVAKVQELQER--GLKVAMVGDGVNDSPALAHADLGIAIGTGTDVAIEAADIVLIR------NDLLDVVASIELSKKTVQRIRINFVFALIYNLLGIPFAAGVFMPLGLVLQPWMGSAAMAASSVSVVLSSLLLRLFKKTS-----VEEYESRAQSHKLSLS---PSQVSTHVGLESR-----------RCSPLSDRKRRSRSASGSSSFISGSFHPSTTQPYNTSGRSIV--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYT4-1", "uniprot_id": "Q9VYT4_DROME", "id": "Q9VYT4-1", "name": "P-type Cu(+) transporter", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MPSDERVEATMSTVRLPIVGMTCQSCVRNITEHIGQKSGILGVRVILEENAGYFDYDPRQTDPARIASDIDDMGFECSYP------------------------------------------------------------------------------------------------------GDAADPP---------------------------------ETPASAWTNIRVVGMTCQSCVRNIEGNIGTKPGIHSIEVQLAAKNARVQYDPAQYDPAQIAELIDDMGFEASVQEPRSPS--------------QSPSPAPASSPKKRATPTPPPPSYAQNGSAVAIPVEQELLTKCFLHIRGMTCASCVAAIEKHCKKIYGLDSILVALLAAKAEVKFNANVVTAENIAKSITELGFPTELIDEPDNGEAEVELEIMGMTCASCVNKIESHVLKIRGVTTASVTLLTKRGKFRYITEETGPRSICEAIEALGFEAKLMTGRDKMAHN-YLEHKEEIRKWRNAFLVSLIFGGPCMVAMIYFMLEMSDKGHAN-------------------MCCLVPGLSMENLVMFLLSTPVQFFGGFHFYVQSYRAIKHGTTNMDVLISMVTTISYVYSVAVVIAAVLLEQNS--SPLTFFDTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSLKAADALLVEISPDFDIISEKVISVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCDESLITGESMPVAKRKGSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIGFSNPNLVPVAMEH-KMHMDQNTIIVSYAFKCALSVLAIACPCALGLATPTAVMVATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKVTLFVTAQ-VCSLARALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQAGSFGKSSHFQAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRSVRKSMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKGHTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGIR--TVYAEVLPSHKVAKIQRIQAN--GIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEASDIVLMR------NDLLDVVACLDLSRCTVRRIRYNFFFASMYNLLGIPLASGLFAPYGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKPTAKTLRTAEYEAQLAAERASGSEDELDKLSLHRGLDDLPEKGRMPFKRSSTSLISRIFMHDYGNITSPDAKYGEGLLDPEEQYDGRTKIVRSRFHANDSTELQKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38995-1", "uniprot_id": "ATU2_YEAST", "id": "P38995-1", "name": "Copper-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREVILAVHGMTCSACTNTINTQLRALKGVTKCDISLVTNECQVTYDN-EVTADSIKEIIEDCGFDCEILRDSE-----------------------------------------------------------------------------------------------------------------------------------------ITAISTKEGLLSVQGMTCGSCVSTVTKQVEGIEGVESVVVSLVTEECHVIYEPSKTTLETAREMIEDCGFDSNIIMDGNGN-------------------------------------------------------------ADMTEKTVILKVTKAFEDESPLILSSVSER-----------------------------------------------------------FQFLLDLGVKSIEISDDMHTLTIKYCCNELGIRDLLRHLERTGYKFTVFSNLDNTTQLRLLSKEDEIRFWKKNSIKSTLLAIICMLLYMIVPMMWPTIVQDRIFP--------------YKETSFVRGLFYRDILGVILASYIQFSVGFYFYKAAWASLKHGSGTMDTLVCVSTTCAYTFSVFSLVHNMFHPSSTGKLPRIVFDTSIMIISYISIGKYLETLAKSQTSTALSKLIQLTPSVCSIISDVER---NETKEIPIELLQVNDIVEIKPGMKIPADGIITRGESEIDESLMTGESILVPKKTGFPVIAGSVNGPGHFYFRTTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNISANPPVAFTANTKADN------FFICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFDKTGTLTTGFMVVKKFLKDSNWVGNVDEDEVLACIKATESISDHPVSKAIIRYCDGLNCN-----KALNAVVLESEYVLGKGIVSKCQVNG----------------------------------------------------------------------------NTYDICIGNEALILEDALKKSGFINSNVDQ----GNTVSYVSVNGHVFGLFEINDEVKHDSYATVQYLQRNGYETYMITGDNNSAAKRVAREVGISFENVYSDVSPTGKCDLVKKIQDKEGNNKVAVVGDGINDAPALALSDLGIAISTGTEIAIEAADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNLFWALCYNIFMIPIAMGVLIPWGITLPPMLAGLAMAFSSVSVVLSSLMLKKWTPPD-------------------------------------------------IESHGISDFKSKFSIGNFWSRLFSTRAIAGEQDIESQAGLMSNEEVL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : **.* :*. .* :: .*: : * : . : : . : ** . : : *:. *.* : : *: . : * . ::. ::* **: : .** : : : : : *: . *: .:: .:: : * *.: . : *: .: : *.:. **: *: * .: * : . : :: ** :: .::. :*: * :** :: :::* .**.*: : *: ::.:*. :: : . * .***. *:: :*::*::** :**.:** **:**:.* .: . :: : : :: :* .*:::: ** *.*.** : * : ****:***.: * *: * **.**:* * . . :* .* :*.*::*:::::*** ****** ** ::. *** ::.:: *. * .* . . . .:: : :*: :****:********:**.**..* **:*:**. ** :.: .:******:* * . :. *: : ::* *:**:. *: :... . . : * * ** : ***. : .:.: :.. : * *. :::. : :. : * ** :: : *. * :. ::**** :* :* :*** .*:::* *: * ::.:* . . :**:****:**:**** :.:*::*.:**::* :*:*:*:: *.* .:. .:.:* *.:**: *:. * **:. **:* *:: * *:.* * :. : * ****** *** *: : . . . . . : ", "identical_positions": 223, "similar_positions": 297, "identity": "13.97%" }, { "cls_id": "homologset.agr.SGD:S000002680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZP3-1", "uniprot_id": "PNKD_MOUSE", "id": "Q69ZP3-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAGLAVAVDPSDP-RAVQASIEKERVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR----QRMERKSTCPSTLGEERAYNPFLRTHCLELQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXB0-1", "uniprot_id": "D3ZXB0_RAT", "id": "D3ZXB0-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAWAIGFPCGILFFVLTKQEVDKDRLKQMKARQNMRVSNTGEYSLYTRTWLGYLFYRQQLRRARNRFPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAGLAVAVDPSDP-RAVQASIEKERVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENVARERKMQWVQR----QRMERKSTCPSTLGEERAYNPFLRTHCLALQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N490-1", "uniprot_id": "PNKD_HUMAN", "id": "Q8N490-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDP-RAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGNAETMLSSLDTVLGLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR----QRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB32-1", "uniprot_id": "HAGHL_MOUSE", "id": "Q9DB32-1", "name": "Hydroxyacylglutathione hydrolase-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLEDNYMYLIIEEHTREAVAIDVAVA-ERLLEIAGREGVSLTMVLSTHHHWDHTRGNAELAHILP------GLAVLGA-DERICALTRRLEHGEGLQFGAIHVRCLLTPGHTSGHMSYFLWEDDCPDSPALFS---------------------------GDALSVAGCGWHLEDTAQQMYQSLAKTLGTLP-----PETKVFCGHEHTLSNLEFAQKVEPCNEHVQAKLSWAQE----RDDEDIPTVPSTLGEELMYNPFLRVTEDAVRAFTG---------QVAPAQVLEALCRERARFQPAVEPPQP-QVRALLALQWGLLSTHQKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L628-1", "uniprot_id": "A0ABK0L628_RAT", "id": "A0ABK0L628-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLEDNYMYLIIEEHTREAVAVDVAVP-KRLLEIAGREGVSLTTVLSTHHHWDHTRGNAELARLQP------GLAIMGA-DERICALTRRLEHGEELQFGAIHVRCLLTPGHTSGHMSYFLWEDECPDPPALFSGTLQPGLTYQPNSTVSSRPPSDPLCSLGDALSVAGCGWHLEDTAQQMYQSLAKTLGTLP-----PQTKVFCGHEHTLSNLEFAQKVEPCNSHVQAKLSWAQK----RDDDDVPTVPSTLGEELMYNPFLRVTEDPVRAFTG---------QVAPAQVLEVLCRERARFQLASEPPQP-QVRALLALQWGLLSTGQEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PII5-1", "uniprot_id": "HAGHL_HUMAN", "id": "Q6PII5-1", "name": "Hydroxyacylglutathione hydrolase-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVP-KRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLRP------GLAVLGA-DERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFS---------------------------GDALSVAGCGSCLEGSAQQMYQSLAE-LGTLP-----PETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACGHSRRG---------MRMTCPLCRRLWARSASTTPSCGWREYGCCPGASTVTWTLRKASGDCVLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KB8-1", "uniprot_id": "GLO2_MOUSE", "id": "Q99KB8-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVLGRGS-----LCLRSLSALG-ATCARRG-LGQALLGLSLCHSD-----------------------------------------------------------------FRKNL---------------TVQQDIMKVELLPALTDNYMYLIIDEDTQEAAIVDPVQP-QKVIEAAKKHHVKLTTVLTTHHHWDHAGGNEKLVKLEP------GLKVYGG-DDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFT---------------------------GDTLFVAGCGKFYEGTADEMYKALLEVLGRLP-----PDTKVYCGHEYTVNNLKFARHVEPGNAAIQEKLAWAKE----KYAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAG---------ETDPVTTMRAIRREKDQFKVPRD---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35952-1", "uniprot_id": "GLO2_RAT", "id": "O35952-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVLGRGS-----LCLRSLSVLG-AACARRG-LGQALLGLSLCHTD-----------------------------------------------------------------FRKNL---------------TVQQDMMKIELLPALTDNYMYLIIDEDTQEAAVVDPVQP-QKVIETVKKHRVKLTTVLTTHHHWDHAGGNEKLVKLEP------GLKVYGG-DDRIGALTHKVTHLSTLEVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFT---------------------------GDTLFVAGCGKFYEGTADEMYKALLEVLGRLP-----PDTKVICGHEYTVNNLKFARHVEPGNTAVQEKLAWAKE----KNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAG---------ETDPVTTMRAIRREKDQFKVPRD---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16775-1", "uniprot_id": "GLO2_HUMAN", "id": "Q16775-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVVGRGL-----LGRRSLAALG-AACARRG-LGPALLGV-FCHTD-----------------------------------------------------------------LRKNL---------------TVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDPVQP-QKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLES------GLKVYGG-DDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFT---------------------------GDTLFVAGCGKFYEGTADEMCKALLEVLGRLP-----PDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKE----KYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAG---------ETDPVTTMRAVRREKDQFKMPRD---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P963-1", "uniprot_id": "GLO2_DANRE", "id": "Q6P963-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------------------MWFRSLAVSA-CTVGVLGALSQKFAPTALFHSA-----------------------------------------------------------------IRKSS---------------LVEQSDMKVELLPALTDNYMYLLIDEETKEAAIVDPVEP-QKVVDAVKKHGVKLKTVLTTHHHWDHAGGNEKLVKLMP------GLTVYGG-DDRVGALTQKVTHYNTFKVGSLNVKCLFTPCHTSGHICYFVTKENSTEAPAVFT---------------------------GDTLFVAGCGKFFEGTADEMYKALIEVLGRLP-----PETRVYCGHEYTINNLKFARHVEPNNEVIRTKLAWAKE----KYDNGEPTIPSTVAEEFTFNPFMRVREKSVLEHAG---------TSDPIEAMRSIRKEKDGFRVPKN---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPU3-1", "uniprot_id": "Q8IPU3_DROME", "id": "Q8IPU3-1", "name": "hydroxyacylglutathione hydrolase", "aln": "---MLASAWRSVATSVETQLTATYFRGSSSNPTLLLRSWRTIPRADAPGFGAIRRRFLAVPVICPS-----------------------------------------------------------------LVKLQKLRKVGFRGMHSTLEDVQLEGMEIKILPALQDNYMYLIVDTKTREAAVVDPVEP-ELVIKTVQEQQLTLSKVLTTHHHWDHAGGNEKLLKLWEK-----ELDVYGG-DDRIGALNKKVQQDDTFTIGGLHVKCLSTPCHTTGHICYHITAQQGSGEGAVFT---------------------------GDTLFQGGCGRFFEGTPEEMYEALCTKLSALP-----DATKVFCGHEYTLQNMSFARHVEPDNEVIQQRIEWAKH----RRASQDPTVPSTIGEEKSWNPFMRVHEATVQKHAGG--------ATDPVVTMGKLRKEKDTFKA------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05584-1", "uniprot_id": "GLO2_YEAST", "id": "Q05584-1", "name": "Hydroxyacylglutathione hydrolase, cytoplasmic isozyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MQVKSIKMRWESGGVN-YCYLLSDSKNKKSWLIDPAEPPEVLPELTEDEKISVEAIVNTHHHYDHADGNADILKYLKEKNPTSKVEVIGG-SKDCPKVTIIPENLKKLHLGDLEITCIRTPCHTRDSICYYVKDP-TTDERCIFT---------------------------GDTLFTAGCGRFFEGTGEEMDIALNNSILETVGRQNWSKTRVYPGHEYTSDNVKFVRKIYPQVGENKALDELEQF----CSKHEVTAGRFTLKDEVEFNPFMRLEDPKVQKAAGDTN-----NSWDRAQIMDKLRAMKNRM--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . : * **: : : :* . . : . :.: :: **:*:**: ** .: : : *. .. :. : . . .* : : .: ** ** . : * : .:*: ** * .*** *.. : * :* : * : ***:: .*: *. : * . : . . : * : ", "identical_positions": 36, "similar_positions": 63, "identity": "7.24%" }, { "cls_id": "homologset.agr.SGD:S000002681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RUW1-1", "uniprot_id": "TOLIP_RAT", "id": "A2RUW1-1", "name": "Toll-interacting protein", "aln": "----------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQQQIQLDAQAAQQLQYGGAVGTVGRLSITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI---------------FDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQG--------------VGYVPIAGMPAVCSPGMVPMAMPPPA-VAPQPR--------CNEEDLKAIQDMFPNMDREVIRS------VLEAQRGNKD-------------AAINSLLQMGEES-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ06-1", "uniprot_id": "TOLIP_MOUSE", "id": "Q9QZ06-1", "name": "Toll-interacting protein", "aln": "----------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQQQIQLDAQAAQQLQYGGTVGTVGRLSITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI---------------FDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQG--------------VGYVPIAGMPAVCSPGMVPMAMPPPA-VAPQPR--------CNEEDLKAIQDMFPNMDREVIRS------VLEAQRGNKD-------------AAINSLLQMGEES-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0E2-1", "uniprot_id": "TOLIP_HUMAN", "id": "Q9H0E2-1", "name": "Toll-interacting protein", "aln": "----------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQRQVQLDAQAAQQLQYGGAVGTVGRLNITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLEI---------------FDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAAMVMPPQPVVLMPTVYQQG--------------VGYVPITGMPAVCSPGMVPVALPPAA-VNAQPR--------CSEEDLKAIQDMFPNMDQEVIRS------VLEAQRGNKD-------------AAINSLLQMGEEP-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV43-1", "uniprot_id": "TOLIP_DANRE", "id": "Q7ZV43-1", "name": "Toll-interacting protein", "aln": "----------------MATTISTQRGQVYIGELP-QDFLRIMPTQQQQQVQLDAQAARQLQYGGSLGTAGRLSITVVQAKLAKNYGMTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI---------------FDERAFSMDDRIAWTHVTIPENLREGTVVDEWYSLSGRQGDDKEGMINLVMSFATIPAGMMMQPQPVVLMPTVYQQG--------------VGYVPIAGVPGMYNQGVVPMGMPAAAPVASQSAP-------CSEEDLKALQDMFPNLDKEVIRT------VLEAQQGNKD-------------AAINSLLQMAEEL-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05610-1", "uniprot_id": "DON1_YEAST", "id": "Q05610-1", "name": "Donuts protein 1", "aln": "MGKKNRKGKENNAAKTSFLKVENIKNTNSGLELPSQDYTNVEEKESSPKTDFPLITKEHVNTKTDSNILDYPTIGDLVSSVEKLCVLKELKIAFPEVDDTLIKAILIASQGVLEPAFNSLLYYSSPEENTDFALPMKPISVEDYSKINVSEILQREIFDDIEDEFSGQGINGSMVISKIESELSSLAEHIGNISTPGSNREVAESTRNVAVAEGHNTILSNEDSILKGKEKGKEEEKEKGEEKGVNSLKGAAVKVVAKSLKNNRIPVTVKRNEPSNNLFDVLNCDESEEEEEQDVETNTSNQERKNQGGNTEVPEAQRDSADRLPAKDDGGYKSAFGTDSCGLFAADAKDEKKQVHPSRQELSFT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.. :. *** **: .: .:.. : :: : .::: . . .* : :.: * :..:. . : * :*. :* :*.:: : * .* * : : :* : * . :: * .: . : .: **: : *: . * :: : ..: :.:: :* * .: * . : . : :. *.*.: : **: .* ..: :. * ***:.. * . :* :. : ", "identical_positions": 35, "similar_positions": 99, "identity": "9.59%" }, { "cls_id": "homologset.agr.SGD:S000002688", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI7-1", "uniprot_id": "EXOS9_MOUSE", "id": "Q9JHI7-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMETAPIDTSNIEERAEEIIAEAEPPPEVVSQPVLWTPGTAQIGDGIENSWGDLEDSEKEEEEEEGGIDEAVILDDTKMDTG-EVSDIGSQGAPIVLSDSEEEEMIILEPEKNPKKIRAQTSAN--QKAPSKGQGKRKKKKRTAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QR75-1", "uniprot_id": "EXOS9_RAT", "id": "Q4QR75-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMEKAPIDTSNIEEKAEEIIAEAEPPPEVVSKPVLWTPGTAQIGEGIENSWGDLEDSEKEEEEE-GGIDETVILDDTKMDTG-EVSDIGSQGAPIVLSDSEEEEMIILEPEKSPKKIRAQTSAN--QKAPSKSQGKRRKKKRTAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06265-1", "uniprot_id": "EXOS9_HUMAN", "id": "Q06265-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG--GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJQ5-1", "uniprot_id": "EXOS9_DANRE", "id": "Q5XJQ5-1", "name": "Exosome complex component RRP45", "aln": "-MRDTPLSNCERLFLLKAIKEKKRLDGRQTYDYRNIKISFGTDYGCCVVELGKTRVLSQVSCELVPPKDSRPTEGIVFFNLELSPMASPAFEPNRQS-ELLVTLNRQLERCLRNSKCIDTESLCVVSGEKVWQIRVDVHVLNHDGNLMDAASIAAISALSHFRRPDVAIQGRDVTVFGPEERDPIPLSIYHMPICVSFAFFLQG------------SFLLVDPCEREERVKDGLLVIAMNKHREICSIQSSGGIMLLKEQVLRCSKIASVKVSEITELINKALENDKKVRKEGGKFGFAESMPKERITTLKRDEAPVEMTDVKETADDIVQRTETTTETVPSPILVATGTAQIGEGIVNSWG-LDEDE----------DDELQTEDRKTDEV------------VVITDSEEEEVVILNDQK------------------SKKTSKQK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05636-1", "uniprot_id": "RRP45_YEAST", "id": "Q05636-1", "name": "Exosome complex component RRP45", "aln": "MAKDIEISASESKFILEALRQNYRLDGRSFDQFRDVEITFGKEFGDVSVKMGNTKVHCRISCQIAQPYEDRPFEGLFVISTEISPMAGSQFENGNITGEDEVLCSRIIEKSVRRSGALDVEGLCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITVHGEQIIVHPVNEREPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVLTVTLNKNREVVQVSKAGGLPMDALTLMKCCHEAYSIIEKITDQILQLLKEDSEKRNK-----YAAMLTSENAREI-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* .* *:*.*:.:: *****. ::*::.*:**.::* *::*:*:* ::**::. * .*. **:..:. *:* **.. ** .. : : * .* :*:.:*.* .:*.*.**:*:*.* * :*.*:*.*: **.::**:.**.: .* **::**::::* :: :. :**:*:**.* *:****:*:** ::*. :** : **:*.:::**:**: :..:**: : :::*.: * : :**: * : *::*.. *:: :* :..:. : ", "identical_positions": 95, "similar_positions": 126, "identity": "20.88%" }, { "cls_id": "homologset.agr.SGD:S000002690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU34-1", "uniprot_id": "E9PU34_RAT", "id": "E9PU34-1", "name": "", "aln": "MPARQLQTLAGLHSISSKAHQCQRLTRLTLRPLTKFESTACHNSLTIQQHLDSFLPSITADSLNKPKIPETSRVISNASRLFPLNAVHWLDRKEHRPSMHAFGTHRSMTHKPNFLCSKWFIKAVKRHHSSVSNEALVPKQDLPQIKRPLKASRTRQPSRTNLPDLSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPR----DAANILVMGVESSAKEGDAGTIFLFREGAAVFWNVKDKTMKHVMQVLERHETQPYEVALVHWENEELNYTKTEGQSKLHRGEIKLNS-------------------ELDLDDSILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIPEALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLITPDFYWDRANLEELYDKTCQFLSITRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI78-1", "uniprot_id": "RMND1_MOUSE", "id": "Q8CI78-1", "name": "Required for meiotic nuclear division protein 1 homolog", "aln": "MPSRLLHTLASLHSISAKAHQCQRLTWLTLRPLRKSESTTCHNGLTIQQHLHSFFPSITADSLNKPEILEMSRITSDTSRLFPLNAVHWLDGKEHWPSMHPFGTHRSMTHKPNLLCSKWFIKAVKRHHSSVSNEALVPKQDLPQIKRPLKASRTRQPSRTNLPDLSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPR----DAANILVMGVESSAKEGDPGTIFLFREGAAVFWNVKEKTMKHVMQVLERHETQPYEVALVHWENEELNYIKTEGQSKLHRGEIKLNS-------------------ELDLDDAILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIPEALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLITPDFYWDRANLEELYDKTCQFLSITRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWS8-1", "uniprot_id": "RMND1_HUMAN", "id": "Q9NWS8-1", "name": "Required for meiotic nuclear division protein 1 homolog", "aln": "MPATLLRAVARSHHILSKAHQCRRIGHLMLKPLKEFENTTCS-TLTIRQSLDLFLPDKTASGLNKSQILEMNQKKSDTSMLSPLNAARCQDEKAHLPTMKSFGTHRRVTHKPNLLGSKWFIKILKRHFSSVSTETFVPKQDFPQVKRPLKASRTRQPSRTNLPVLSVNEDLMHCTAFATADEYHLGNLSQDLASHGYVEVTSLPR----DAANILVMGVENSAKEGDPGTIFFFREGAAVFWNVKDKTMKHVMKVLEKHEIQPYEIALVHWENEELNYIKIEGQSKLHRGEIKLNS-------------------ELDLDDAILEKFAFSNALCLSVKLAIWEASLDKFIESIQSIPEALKAGKKVKLSHEEVMQKIGELFALRHRINLSSDFLITPDFYWDRENLEGLYDKTCQFLSIGRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P054-1", "uniprot_id": "A0A8M9P054_DANRE", "id": "A0A8M9P054-1", "name": "", "aln": "---MFVKMLWRLQQPLKSTQACG----FTLRQING-------------------LNSVTSNRLN----------CSTLALQTPFKDQRNCPAILHHCILQKGGPRFQVLTPLNFISKTWSFQV--RLQSTTAATNIVLKQGGMSGKRTFKGPRTKQPSRASQP--SLEEDLMQCIAYATADQYHLPTLCHDLIAHGFSEIKEFPR----DASNVLVMGTDNSAKPYDSGTIFFFREGSVVFWNVEDKTMKTTMKILEQHEIQPYEVALVYWENEEINYTVGEGHSKLRHGVFLFNE-------------------ELDYEQVILEKFAFSNALSLSVKLAIWEVTLDSFVESIQSIPEMLKSGQRVKLSRADVMQKIGELFSLRHCINLSSDLLITPDFYWDREDLELLYDKTCQFLNINRRVKVVNEKLQHCTELTDLMRNHLSEKHSLRLEWMIVVLITIEVMFELARVIF----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXQ8-1", "uniprot_id": "Q9VXQ8_DROME", "id": "Q9VXQ8-1", "name": "DUF155 domain-containing protein", "aln": "------------------------------------------------------------------------MNFARLRFGQMVLGGLRIPRQQTQTQWMMDRRRWLASEATSSAAAPAQAASVPRTQTQPRVKPLPLAEERLESILSPIRTRIIRKKRLAIDELSALG-FLNTRGYTTAEEYNLEDLQIALREQNLYETKRFFSTDNLDVEQNVLFVAAKYPTGQQPREIFFFREGSVVFWNCSDIETNNVLSFLRAFERESYVSALVHGESEVMPYTYIPSTAVDVEGDLVAESSDFNVTSRAFFQ--NGKFFVTADTDSFLYKYTFSNAMAQSIKLGMWEATLDRYIDSIEHLTEDLKRGRRLRISRAAMLRKTGELFALRHVINLSSDLLDAPDFYWDREELEALYLQVCSYFSISRRTKVMNEKINHCVELAELVSHNLNDAHHIRLEWMIIILIMVEVGFEVLHFVSDHSDSHKLEVLPLAAPAASIPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05648-1", "uniprot_id": "MRX10_YEAST", "id": "Q05648-1", "name": "MIOREX complex component 10", "aln": "-------------------------------------------------------------------MLSFRSLTSTFGFVSRFQIRRLGTSLSIQNLEVQDGRWKGKLATEKKTNREHKSVDTNIKTMKMLKNPKNSTRYLRRSFVPNHRKQENGRDILEDSLSKDHLKVKSCITITTGEGYDLKRCMKLLTMQGLQPTNLIPD-------EIVSFSYQDNGNKGD--VMILGQNGSIVSWGFSESSVRNCIVPIVKAAS-LNPLNGEDFETEDMDYVEIEGEQDFDKLSSLDNKVTPRIACESFLSGDLIIINSLDSDQGMLDKAAFSSGLSRSTNLAVLEEAMEKHISKTRTITENISKGTKLNLRSSDALKSIGRLFLIRGKLNLYSELIETPDLYWSEPQLEEIFKNVSRYLDIGPRINILNSKLDYSTDECRALISLLNERNSTFLEWIIIYLIAFELCFEIYHFYQKYSSYCSEPTNDDLDATK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : . . . :*.: *.* * . . : : : : . . : ::: ::*: * *. .: . : : *.* : * . . :. : :* * :**..:. * :*.: * ::: .:.. . :.* :. * ::.: ::. *.** :* :** *::: :**:**.. :** :: :.. ::.* * :::*.*:::. : : *.: . ***:*: ** .*: **: :. ", "identical_positions": 46, "similar_positions": 108, "identity": "9.29%" }, { "cls_id": "homologset.agr.SGD:S000002691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7V9-1", "uniprot_id": "E2AK4_RAT", "id": "D4A7V9-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGAAGRGPAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLYPQG--LAGEEVYVQVELRVKCPPTYPDVVPEIELKNTKGLSNESVNLLKSHLEELAKKQCGEVMIFELAHHVQSFLSEHNKPP-PKSFHEEMLERQAQEKQQRLLEARQKEEQEQREILHEIQKRKEEIKEEKKRKEMAKQERLEITSLTNQDHASKRDPAGHRAAAFLHGGSPDFVGNGKARAHSSGRSRRERQYSVCSGEASPGSCDILYFCVGSADQLMVHKGKCVGS-DEQLGKVVYNALETATGSFVLLYEWVLQWQKKMGPCLTS--------QEKEKIDKCKKQIQGAETEFSSLVKLSHPNIVRYFAMNSREEKDS-----IVVDILAEHISGISLAAHLSHSGPVPMHQLRKYTAQLLAGLDYLHRNSVVHKVLSTASVLVDAEG------------TVKITDYSISKRLADICKEDVFEQTRVRFSDSALPYKTGKKG---DVWRLGLLLLSLSQGQECEE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSGGQDYIETIIPSNQLPS---------------------AAFFTETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-QFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAVPGTPPPDYIPQAQNSSATGGKASGDTEELGSVEAAAPPPILSSSVEWSTSAERSNSARFPVTGQDSSSDEED-EDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNEKDSRHEI---------EPSVTTEAVHYLYIQMEYCEKSTLRDTIDQG-LFRDTSRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFNAEGKQDDQAGDHVIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIILFEMSYHPMVTASERIFVLNQLRDPTSPKFPDDFEDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLANTDGKAYRTMMSQLFCQHSSPAIDYTYDS----------DILKGNFLIRTAKIQQLVCETIVRVFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTAN-SSLPTAETIYTIYEVIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLTPTINSLIKQKTGIAQLVKYSLKDLEEVVGLLKKLGVKLQVSINLGLVYKVQQHN--GIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQALG-------PVPTAVGVSIAIDKIFAAVLNMGEPVT-------------------VSSCDLLVVSAGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGD--------------ERNFRDASDNLAVQTLKGSFSNASGLFEIHGTTVVP--TVSVISPEKLSASTRRRHEIQVQTRLQTTLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ05-1", "uniprot_id": "E2AK4_MOUSE", "id": "Q9QZ05-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGASGRGRAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLYPQG--LAGEEVYVQVELQVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSHLEELAKKQCGEVMIFELAHHVQSFLSEHNKPP-PKSFHEEMLERQAQEKQQRLLEARRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEITSLTNQDYASKRDPAGHRAAAILHGGSPDFVGNGKARTYSSGRSRRERQYSVCSGEPSPGSCDILHFSVGSPDQLMVHKGRCVGS-DEQLGKVVYNALETATGSFVLLHEWVLQWQK-MGPCLTS--------QEKEKIDKCKRQIQGAETEFSSLVKLSHPNIVRYFAMNSREEEDS-----IVIDILAEHVSGISLATHLSHSGPVPAHQLRKYTAQLLAGLDYLHSNSVVHKVLSASSVLVDAEG------------TVKITDYSISKRLADICKEDVFEQARVRFSDSALPYKTGKKG---DVWRLGLLLLSLSQGQECGE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKLPLVEQSPEDSGGQDYIETVIPSNQLPS---------------------AAFFSETQKQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-HFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAVPGTPPPDCTPQAQDSPATCGKTSGDTEELGSVEAAAPPPILSSSVEWSTSAERSTSTRFPVTGQDSSSDEED-EDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNQKDGSHEI---------EPSVTAEAVHYLYIQMEYCEKSTLRDTIDQG-LFRDTSRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFTAEGKQDDQAGDGVIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPDDFDDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLANIDGKAYRTMMSQIFCQHISPAIDYTYDS----------DILKGNFLIRTAKIQQLVCETIVRVFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTTN-SSLPTAETIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLTPTINSLIKQKTGVAQLVKYSLKDLEDVVGLLKKLGVKLQVSINLGLVYKVQQHT--GIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQTVG-------PVPTAVGVSIAIDKIFAAVLNMEEPVT-------------------VSSCDLLVVSVGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGD--------------ERNFRDASDNLAVQTLKGSFSNASGLFEIHGTTVVP--NVIVLAPEKLSASTRRRHEIQVQTRLQTTLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K8-1", "uniprot_id": "E2AK4_HUMAN", "id": "Q9P2K8-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQG--LTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPP-PKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHRANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGS-DEQLGKLVYNALETATGGFVLLYEWVLQWQKKMGPFLTS--------QEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVRYLAMNLKEQDDS-----IVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEG------------TVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKG---DVWRLGLLLLSLSQGQECGE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSEGQDYVETVIPSNRLPS---------------------AAFFSETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-QFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSASARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKNGCHES---------EPSVTTEAVHYLYIQMEYCEKSTLRDTIDQG-LYRDTVRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGD-LIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLTNVDGKAYRTMMAQIFSQRISPAIDYTYDS----------DILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTTN-SFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHN--GIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALG-------PVPTAIGVSIAIDKISAAVLNMEESVT-------------------ISSCDLLVVSVGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTD--------------ERNGREASDNLAVQNLKGSFSNASGLFEIHGATVVP--IVSVLAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHX7-1", "uniprot_id": "A0A0B4KHX7_DROME", "id": "A0A0B4KHX7-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGLETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELAQTVQAFLLEHNKPP-KGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGR--------------------------------QIQRGCCVGEGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMGSHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEG-----LLVYLVQDFLLGTSVFSISSSLG-WCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTG------------NVRVSDFSLVPNLLELLSG---------------AGQSSSCG---DLPALGALVESLMPTN------------------SYEMRDFVDKCNSD---RTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQ---------------------IPTLALSQ---SRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIES----------------------------------VDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDE-EDSSSSMWNGYIPNMEDSDSDGIEFVDSNGKVAVYDDE---EQEDSTRG---------KTNSPKPLMQVMYIQMEFCEKCTLRTAIDDN-LFNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVN-QITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIIDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFN--FHPKQSYDCSFDIIAPTTG-SHLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEAASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGHPSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDC-------------------RAIDVGICVCGTRPPLKDV-TYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAEN------GSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSGGKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTLSQFLKKET-FVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEINEEVVDYLSDAKTPIVALYSISDSYYRVII---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15442-1", "uniprot_id": "GCN2_YEAST", "id": "P15442-1", "name": "eIF-2-alpha kinase GCN2", "aln": "--------MSLSHLTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKS-SWDKQPQIIFEITLRS--VDKEPVESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSFTQEKLDEFQNVVNTQSLEDDRLQRIKETKEQLEKEEREKQQETIKKRSDEQRRIDEIVQRELEKRQDDDDDLLFNRTTQLDLQPPSEWVASGEAIVFSKTIKAKLPNNSMFKFKAVVNPK------------------------------PIKLTSDIFSFSKQFLVKPYIPPESPLADFLMSSEMMENFYYLLSEIELD--------NSYFNTSNGKKEIANLEKELETVLKAKHDNVNRLFGYTVERMGRNNATFVWKIRLLTEYCNYYPLGDLIQSVGFVNLATARIWMIRLLEGLEAIHKLGIVHKCINLETVILVKDADFGSTIPKLVHSTYGYTVLNMLSRYPNKNGSSVELSPSTWIAPELLKFNNAKPQRLTDIWQLGVLFIQIISGSDIVMNFETPQEFLDSTSMDETLYDLLSKMLNNDPKKRLGTLELLPMKFLRTNIDSTINRFNLVSESVNSNSLELTPGDTITVRGNGGRTLSQSSIRRRSFNVGSRFSSINPATRSRYASDFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRH---TEEKLSTILSEVMLLASLNHQYVVRYYAAWLEE------------------------------DSMDENVFESTDEESDLSESSSDFEENDLLDQSSIFKNRTNHDLDNSNWDFISGSGYPDIVFENSSRDDENEDLDHDTSSTSSSESQDDTDKESKSIQNVPRRRNFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLP-----GSSDNLTSAIGTAMYVATEVLD--GTGHYNEKIDMYSLGIIFFEMIYP-FSTGMERVNILKKLRSVS-IEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLP--VKHQDEVIKEALKSLSNPSSPWQQQVRESLFNQSYSLTNDILFDN------------SVPTSTPFANILRSQMTEEVVKIFRKHGGIENNAPPRIFP---KAPIYGTQNVYEVLDKGGTVLQLQYDLTYPMARYLSKNPSLISKQYRMQHVYRPPDHSRSSLEPRKFGEIDFDIISKSSSESGFYDAESLKIIDEILTVFPVFEKTNTFFILNHADILESVFNFTNIDKAQRPLVSRMLSQVGFARSFKEVKNELKAQLNISSTALND-------LELFDFRLDFEAAKKRLYKLMIDSPHLKKIEDS-LSHISKVLSYLKPLEVARNVVISPLSNYNSAFYKG-GIMFHAVYDDGSSR----NMIAAGGRYDTLISFFARPSGKKSS-----NTRKAVGFNLAWETIFGIAQNYFKLASGNRIKKRNRFLKDTAVDWKPSRCDVLISSFSNSLLDTIGVTILNTLWKQNIKADMLRDCSSVDDVVTGAQQDGIDWILLIKQQAYPLTNHKRKYKPLKIKKLSTNVDIDLDLDEFLTLYQQETGNKSLIN------DSLTLGDKADEFKRWDENSSAGSSQEGDIDDVVAGSTNNQK-VIYVPNMATRSKKANKREKWVYEDAARNSSNMILHNLSNAPIITVDALRDETLEIISITSLAQKEEWLRK----VFGSGNNSTPRSFATSIYNNLSKEAHKGNRWAILYCHKTGKSSVIDLQR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: : * :**:.:.:*: *. ** : .:* : : . *:. .. ** *:*.::: :.: :. :: *:..:: : *: :*:*:: .* * *.:: *: :: *: : .:: :.::. : .* .: .* .: * ::: . . . ... . : . .. . :: : . .* * : . :: * :: . .. . .. : . *.:..:: : .* *: . . : :: :. .: . * * :* .* :* .: *. : .*:: . . : .: . : :... *: ** *. .: . : *::.* . .. :** *:. . . . : . : . ** :** : **:**** *:*.:* **. **:*:* :. : ** **: *:*: :***: :*:* . ::: *. . . . : . *:.: : .. : . .. :.: .. .. : :.: :::. :. . ::****:**: ** *.. * .: . *****:* :.*::**.:*:*******:***:*. ::********. . .. *. :**::**:.*: . .. **:*:*:::****:*** : *. ** : **. : :.* : .:: *::*** :** * ** * :* . .*: : ::*:* .. : : : * . . : :. : . : ::.:*::**.:: :* : :. .: :.* :: * ** :**::: * ::* :::*:* . :.*:: : ***:: ::. * : ** : *: :* :.: * : :**: :*.::: . .: : : : : : : . : .* : ::: : .*: . .: * .:. *:. * : : * . . **::: : .::* * *** :: * . .. *..:: :.: . . : : . . :. : . **. .* . :: *. : : : : .: : :.:: :: . :* :.: : . : . . . * ... . : : . . : . .:* : .: : :: : ::.*: ::. : . . . . * : : . . **. . :: ", "identical_positions": 209, "similar_positions": 484, "identity": "11.64%" }, { "cls_id": "homologset.agr.SGD:S000002692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0VBU9-1", "uniprot_id": "PLPP4_MOUSE", "id": "Q0VBU9-1", "name": "Phospholipid phosphatase 4", "aln": "--------------MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIW-----------------LYKNP-LVQSDNIPTR---------LMFAISFLTPLAVICVVKIIRRTDKTEI----------------------------KEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDG---------------VMNSEMRCTGD-----PDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGG-------------VIGLIFAYICYRQHYPP--------LANTACHKPYVSLRVPTS------LKKEERPTADSAPSLPLEGITEGPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZY2-1", "uniprot_id": "PLPP4_HUMAN", "id": "Q5VZY2-1", "name": "Phospholipid phosphatase 4", "aln": "--------------MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIW-----------------LYKNP-LVQSDNIPTR---------LMFAISFLTPLAVICVVKIIRRTDKTEI----------------------------KEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDG---------------VMNSEMHCTGD-----PDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGG-------------VIGLIFAYICYRQHYPP--------LANTACHKPYVSLRVPAS------LKKEERPTADSAPSLPLEGITEGPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KWX4-1", "uniprot_id": "A0ABK0KWX4_RAT", "id": "A0ABK0KWX4-1", "name": "", "aln": "--------------MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIW-----------------LYKNP-LVQSDNIPTR---------LMFAISFLTPLAVICVVKIIRRTDKTEI----------------------------KEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDG---------------VMNSEMHCTGD-----PDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQAVAVTVSR----------RAVPSLHVKEVHQLLCPDSI------LGSSEQQLITTCPRRPCF------VLEISRIQALSCLVFFIFHIIDQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1RRC7-1", "uniprot_id": "A0A8M1RRC7_DANRE", "id": "A0A8M1RRC7-1", "name": "", "aln": "---MKMSPPDRRKYVRELALEIAVRVLLFGVFVFTEFLEPFERIIQPEELW-----------------LYKNP-LVESDHIPKR---------VMFAISFLTPLAVIFVVKIIQRTDRTEI----------------------------KEACLAVSLALALNGVFTNTIKLIVGRPRPDYYQRCFPDG---------------QMNAKMLCTGE-----PDLVSEGRKSFPSSHSSFAFSGLGFTSFYLAGKLQCFTDAGRGRSWRLCAMVLPLYSAMMIALSRICDYKHHWQDAFVGG-------------VIGLFFAYICYRQHYPP--------FLHIDCHLSYASLAAATVHNMP--ASQDQPLPTDNATSLPLEGMTEGPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UMZ3-1", "uniprot_id": "PLPP5_MOUSE", "id": "Q3UMZ3-1", "name": "Phospholipid phosphatase 5", "aln": "--------MG----TAALGAELGVRVLLFVAFLVTELLPPFQRRIQPEELW-----------------LYRNP-YVEAEYFPTG---------RMFVIAFLTPLSLIFLAKFLRKADATDS----------------------------KQACLAASLALALNGVFTNIIKLIVGRPRPDFFYRCFPDG---------------LAHSDLTCTGD-----EDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKSWRLCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGS-------------MIGMTFAYVCYRQYYPP--------LTDVECHKPFQDKHKLPS---------SQKPSELHHLEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEB5-1", "uniprot_id": "PLPP5_HUMAN", "id": "Q8NEB5-1", "name": "Phospholipid phosphatase 5", "aln": "--------MGKAAAAVAFGAEVGVRLALFAAFLVTELLPPFQRLIQPEEMW-----------------LYRNP-YVEAEYFPTK---------PMFVIAFLSPLSLIFLAKFLKKADTRDS----------------------------RQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRCFPDG---------------LAHSDLMCTGD-----KDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGS-------------MIGMTFAYVCYRQYYPP--------LTDAECHKPFQDKLVLST---------AQKPGDSYCFDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6B3Q2-1", "uniprot_id": "A0A8I6B3Q2_RAT", "id": "A0A8I6B3Q2-1", "name": "", "aln": "----ALNFLLTGDPAGTVPSEV-ARWRWAPGGRNRGAPEPRQRLICRPRVWRDGECGPGSGAGRAGPALCGLPGDRAAPSLPAADSARGAVALPEPVIAFLTPLSLIFFAKFLRKADATDS----------------------------KQACLAASLALALNGVFTNIIKLIVGRPRPDFFYRCFPDG---------------MAHSDLTCTGD-----KDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKSWRLCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGS-------------MIGTTFAYVCYRQYYPP--------LTDTECHKPFQDKHRLPS---------SQKPSVPHRLDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05521-1", "uniprot_id": "DPP1_YEAST", "id": "Q05521-1", "name": "Diacylglycerol pyrophosphate phosphatase 1", "aln": "---------MNRVSFIKTPFNIGAKWRLEDVFLLIIMILLNYPVYYQQPFER---------------QFYINDLTISHPYATTERVNNN----MLFVYSFVVPSLTILIIGSILADRRHLIFIL-------------------------YTSLLGLSLAWFSTSFFTNFIKNWIGRLRPDFLDRCQPVEGL------PLDT--LFTAKDVCTTKN-----HERLLDGFRTTPSGHSSESFAGLGYLYFWLCG--QLLTESPLMPLWRKMVAFLPLLGAALIALSRTQDYRHHFVDVILGS-------------MLGYIMAHFFYRRIFPP--------IDDPLPFKPLMDDSDVTL---------EEAVTHQRIPDEELHPLSDEGM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VNU1-1", "uniprot_id": "Q9VNU1_DROME", "id": "Q9VNU1-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "-----------MSKYSKLARGFCDLLIWVALSVASVLLHKMGRPFRRGFFCG----------------DETLSYPARDGTISSK---------VIIAIVLGVPNAVIVVVELFRQLPGGPLREAGG---------KRDSCRIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGRLRPHFLAVCQPMLPDGSSCQDAQNL--GRYIDSFTCSNAN--MTDYQFKELYQSFPSGHASMAMYAMLYLAIYLQAALSTRVS----KLLKHLLQFLFVMFGWYVSLTRIIDYYHHWSDVLAGAALGV-----VFAWLTSAYVADLFAGKRWPKTG------YSANTLRKPQVSPKSSTKSQAG--GSTSGAGQPPALPAYTFGTLPYLAAHPAQAQAQYAQPYHNYGYVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNT8-1", "uniprot_id": "Q9VNT8_DROME", "id": "Q9VNT8-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "-----------MSFNLSLRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRG----------------FFCDDESLMYPYHENTVSP-----TLLHWLGLYLPLISLVVLESFLSHRKDMAPWP--------------------TLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRRRWPLRG----SLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGS-------------LLGAGSALAVTRAAASE--------ELQWRCQDSLASAKQEAAVVDV--ADVKGGQQMPHDLSLVTCHISN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6T4P5-1", "uniprot_id": "PLPR3_HUMAN", "id": "Q6T4P5-1", "name": "Phospholipid phosphatase-related protein type 3", "aln": "MISTKEKNKIPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVG-----------------FQCYDRTLSMPYVETNEELIP--LLMLLSLAFAAPAASIMVAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLG-----TSCEVNPYITQDICSGHD----IHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTK-----LLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKDALRALTQRGHDSVYQQNKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSGAGVRAKWLMMAEKSGAAVANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGGAPWEWKAAGGGAKAEADGGYELGDLARGFRGGAKPPGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAEREAEAEAEGYFRKMQARRFPD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : . . . : * * : * * . . . : ** *:: : . : : : . . .::: :* * . . ", "identical_positions": 10, "similar_positions": 29, "identity": "1.33%" }, { "cls_id": "homologset.agr.SGD:S000002694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWB7-1", "uniprot_id": "YD286_MOUSE", "id": "Q9CWB7-1", "name": "Glutaredoxin-like protein C5orf63 homolog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLWFQGK-----------------SLQIAKSSFG-LLRNLSASN--------------------------------------------------RALPVLTLFTKAPCPLCDEAKEVLQP-YKDRFI------LQEVDITLPEN---------------STWYERYKFDI-PVFHLN-----GQF-LMMHRVNTSKLEKQ--LRKLEQQVLATN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L350-1", "uniprot_id": "A0ABK0L350_RAT", "id": "A0ABK0L350-1", "name": "Glutaredoxin-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MTQEQQAHEREDDTGGRSPRGRAAPVGRKCGAQRKCGGRKRRLDCLRLRIK------------MLWFQGN-----------------SLQIARSSFG-LLRNLSASN--------------------------------------------------TALPVLTLFTKHPCPLCDEAKEVLQP-YKNR----------EVDITLPEN---------------STWYERYKFDI-PVFHLN-----GQF-LMKHRVNTSKLETQ--LLKLEQQVLETN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NC05-1", "uniprot_id": "YD286_HUMAN", "id": "A6NC05-1", "name": "Glutaredoxin-like protein C5orf63", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLWFQGN-----------------SMQLARSSFGLFLRNCSASK--------------------------------------------------TTLPVLTLFTKDPCPLCDEAKEVLKP-YENR--------QPYKDQKLPGTRRRRSPSSPSHPHMASQSGKRYNLTLNQVLSFD-----YDMGLDAPKTISSDCGAFYCLRMFKSPDMTCCFYPKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMI0-1", "uniprot_id": "Q9VMI0_DROME", "id": "Q9VMI0-1", "name": "", "aln": "MPACLRSLSPRCFQQLLRPLGRHLGSYSKAVVIAAAVRTPSAPFRAEEQRLAGLVVDELVKRTSVPREEYNKLIVCSSLKTPAPECRERLSSVAQELGLKCETLALQDDVCSISGLQMTLDCLERGEDQCIITGDTRCQVVQPEHGVLSNELMTVQQPQTRKRAGTELATEPELTPTLGAAALAWTTMQTAQRLNLQPLALLREFAVEQDHEQAMFRLDGREPVTPSDIYTWNMVTGTQKGIPESILGDLHANRLCTHDFKQITASHLLTHLVHSLPAGGLGCAFMGTTDGRSMAMVLEKLVPSIDQVEGLPLLTLYTREPCPLCDDLVEQLEQGFAGQYR------LEKVYIDRKEN---------------VRFLRLFRHDI-PVLFFN-----GQF-LCMHRLNEEALRER--LEALN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05530-1", "uniprot_id": "YD286_YEAST", "id": "Q05530-1", "name": "Glutaredoxin-like protein YDR286C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAFRCSIHTSRVLLH--------------------------------------------------DAGVKLTFFSKPNCGLCDQAKEVIDDVFERKEFHNKAVSLEIVNITDRRN---------------AKWWKEYCFDI-PVLHIEKVGDPKSCTKILHFLEEDDISDK--IRRMQSR----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : . : **:::: * ***: * :. : : . . : : *: :: . . : :: ", "identical_positions": 8, "similar_positions": 27, "identity": "1.85%" }, { "cls_id": "homologset.agr.SGD:S000002695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VUW3-1", "uniprot_id": "Q9VUW3_DROME", "id": "Q9VUW3-1", "name": "Inositol-1-monophosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYRIGE------------------------EKLEVYYQVSLELVR-KCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANAKTP-PELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNA-KKINQALVCYEISLIVVS------KGRDKNVKRLYKLAS-SATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUW2-1", "uniprot_id": "Q9VUW2_DROME", "id": "Q9VUW2-1", "name": "Inositol-1-monophosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAVSE------------------------SKLKEYYDVALKLVL-KCGPLMQEGYQKAKTEYKVKADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQ-AELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKV-TTIKQAVIAYEISLIHAA------GVRDKNVKRLYKMAS-NATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTW5-1", "uniprot_id": "Q7KTW5_DROME", "id": "Q7KTW5-1", "name": "Inositol-1-monophosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHN---------------------------VDVEKCLEVASNLVS-EAGRLIARNNEQ-RQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEESS-GAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGRRIHVSGQ-KELGKALVTSEFGTTRDE------AKMKVVHENFEKMAK-KAHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP62-1", "uniprot_id": "Q9VP62_DROME", "id": "Q9VP62-1", "name": "inositol-phosphate phosphatase", "aln": "MVDEKLPPSKEPAERPPDQTTPGNAATRFGLEDHEATQQDARVNTLRQAEERRGSMVPPDKRAMSMKMSQARLHTINDPNRTGTHSAEATTPPAKPAVNISSRSSLVRGVAPDLPPKPQRPSDSEADLESSDVDRPSAKRKSEKALADVSTSSSEESEKRVPPAAASAPPPAQAEPQWKSIDFAASEAEPIAPPAPRPEDVPLPPPMMSSLPTDGSPDDVQSINSKLTNTDITFHPSKVFASKATNTSGMLYSDEENEPEEEEFPKLPDQFSASDLDTLFLLACREVK-KAGAIALAENKK-NQEYTTKKHTNDIVTPTDNIVEESFIKAISSRYPNHQFIAEERISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNMYTAQLGKGAQMNGEMIRTTGQ-TNLSAAMVLQEYSSGSNE------ARNQVATENSQRLVK-KTHAMRSIGSSAMCLAMVASGVADAFYNFGLHVWDMAAGALIVTEAGGVVMDPAGEELDIMSRRCLAASTDYLALELGNCLQQNYPSPRDDEPRSVNPNEYGPAPETRDFTSQTDFPDSDTPETTDTEIGGEKSATPAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97697-1", "uniprot_id": "IMPA1_RAT", "id": "P97697-1", "name": "Inositol monophosphatase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAD-----------------------------PWQECMDYAVILAR-QAGEMIREALKN-KMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEESVASGEK--TVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQ-EDITKSLLVTELGSSRKP------ETLRIVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKELEIIP-LQRDDES----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55023-1", "uniprot_id": "IMPA1_MOUSE", "id": "O55023-1", "name": "Inositol monophosphatase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAD-----------------------------PWQECMDYAVILAR-QAGEMIREALKN-EMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEK--TVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQ-EDITKSLLVTELGSSRKP------ETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIAKEIEIIP-LQRDDES----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29218-1", "uniprot_id": "IMPA1_HUMAN", "id": "P29218-1", "name": "Inositol monophosphatase 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAD-----------------------------PWQECMDYAVTLAR-QAGEVVCEAIKN-EMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEK--SILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQ-EDITKSLLVTELGSSRTP------ETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIP-LQRDDED----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIN7-1", "uniprot_id": "IMPA2_RAT", "id": "Q8CIN7-1", "name": "Inositol monophosphatase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPNSEEEEELVQG----------------VGPWDECFEVAVQLAL-RAGQIIRKALTE-EKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRE-TDLAKALVLTEIGPKRDP------DTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91UZ5-1", "uniprot_id": "IMPA2_MOUSE", "id": "Q91UZ5-1", "name": "Inositol monophosphatase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPSSEEEGELVQG----------------VGPWDECFEVAVQLAL-RAGQIIRKALTE-EKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRE-TDLAKALVLTEIGPKRDP------DTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14732-1", "uniprot_id": "IMPA2_HUMAN", "id": "O14732-1", "name": "Inositol monophosphatase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPSGEDQAALAA------------------GPWEECFQAAVQLAL-RAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAK--CVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGE-TDLSKALVLTEIGPKRDP------ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTIN-YGRDDEK----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05533-1", "uniprot_id": "INM2_YEAST", "id": "Q05533-1", "name": "Inositol monophosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLTR-----------------------------------QVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVT---KITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : * *:** *: :* : . : :* :*.** . :*. **:::**:*** *::: * . *:. .*::. . : . *.** *.. :..: : ::: * . .. . * * ::: :. :* * ** . **:... *: **** : :: . : . ", "identical_positions": 41, "similar_positions": 65, "identity": "6.77%" }, { "cls_id": "homologset.agr.SGD:S000002696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KXQ8-1", "uniprot_id": "A0ABK0KXQ8_RAT", "id": "A0ABK0KXQ8-1", "name": "MAGE domain-containing protein", "aln": "--------------------------------------------------MPRGHKSK------ARAREKRRQVQD-EAQGLKNAQAKAAEKGESSSCSDH------------------------------------------------------------DSGDAVASTSTA---------------------------VGPYRRSRKSTKG-------------------------PREESTSC--------------------ILMQYLLCKYKMKQPANKGEMLKVINKRFKEQLPDILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPNV-GGTLTTSLPFPQNGLLMPLLGVIFLNGNRASEADIWEFLNILGIHDGKVHIIFG-EPRKLITRDLVKEKYLVYQ--KEANSNPPSFEFLWGPRAYAETTKMKVLEFLAKVNETVPQAFPTHYQEALRDQEERAQAEAVGSPGTSAKDEAESKVRPVNSSCHTEISQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9R3-1", "uniprot_id": "MAGB4_MOUSE", "id": "A2A9R3-1", "name": "Melanoma-associated antigen B4", "aln": "--------------------------------------------------MPRGQKSK------ARAREKRRLVQD-EAQELQDAQAKAGEKGKSPSCSNQ------------------------------------------------------------DSGDAVASTSTAGFPQKSKSQGEAPTTTAR--------KGGACRRSRKSTRG-------------------------PREESTSCTRVPRFSENPQNDLLTRKTGMLMQYLLCKYKMKQPASKGEMLKVINRRFKEQLPEILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPSV-GNALTTSLPFPQNGLLMPLLGVIFLNGNRASEAEIWEFLNVLGIYDGKVHIIFG-EPRKLITRDLVKEKYLVYQ--KEANSDPPSFEFLWGPRAYAETTKMKILEFLAEVNETVPQAFPTHYEEALRDQEERAQAEAVGSPGTSAKDKAEAKVTLVDSSCKYQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSCKDQAESKVTLVDSCKDQAESKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDKAKSKVTLGSSHKYKAKSKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSGKDKAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWY3-1", "uniprot_id": "A0A8I5ZWY3_RAT", "id": "A0A8I5ZWY3-1", "name": "", "aln": "--------------------------------------------------MPRGQKSR------ARAREKRRQTKT-ESQELEGTQTMPSEQKGSSSSSAQ------------------------------------------------------------ASGDAVPSPSSD--TLTKLFQGMSCTTTFS--------ICIACKRADTNAKS-------------------------RRKQNMSSSMAQQ-SKSPKQDLLTRKTGMLMEYMLSKYKHKEPLLREEMLNVVTKSFKEQFPEILKKASNRMDMVFGLELKEIQPKGRSYELVSKLDFQD-DGSGSSELGVPTRGILIPLLSVIYLNNYCAPEKEVWHFLNMLGVYDGVPHIIFG-NARKLITEDLVQEEYLEYR--EVPDSDPPSYQFLWGSKAYSETSQVKVMEFLARINETDSSPSPSNHEESFKAKD-KTQAEGTGQGSTKSKAKKRSKAKSRMPTPTSEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43366-1", "uniprot_id": "MAGB1_HUMAN", "id": "P43366-1", "name": "Melanoma-associated antigen B1", "aln": "--------------------------------------------------MPRGQKSK------LRAREKRRKARE-ETQGLKVAHATAAEKEECPSSSPV------------------------------------------------------------LGDTPTSSPAAG---IPQKPQGAPPTTTAA--------AAVSCTESDEGAKC-------------------------QGEENASFSQATTSTESSVKDPVAWEAGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYTLVSKLNLTN-DGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHLIYG-EPRKFITQDLVQEKYLKYE--QVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEEERAQVRSSVRARRRTTATT-FRARSRAPFSRSSHPM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AHM1-1", "uniprot_id": "A2AHM1_MOUSE", "id": "A2AHM1-1", "name": "", "aln": "--------------------------------------------------MPRGNKSK------SRSRAKRQQMRG-EKPKLQGAQPTGKEEG-KAASPAL------------------------------------------------------------DQGDGPSSSDRG---TAQESQEAASHISPE--------LNVSHPVHDVGAEG---------------------SFAGVDERRANVSIIADAIQCARRDPLTRKASKVLHYLLEKYQKDEQPVEGEMLKLIGRKYKVHFPQILEKATYQLELVYGLELKVDNPATHSYVLVSKLPILP-GADVGGRRELPKTGLILTILGMIFMKGNRATEEEVWQFLHMQGIYPGRRHLIFG-EPRNFITKVLVEQNYVEYR--QVPGSDPPTHEFLWGPRAHEESTYRKVMDILAKIKSAIPSYYPQQYEETLSNQAERAARRDEAGG---FHAARIPSHAQASSSSHI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQ29-1", "uniprot_id": "A0A8I6AQ29_RAT", "id": "A0A8I6AQ29-1", "name": "", "aln": "--------------------------------------------------MPRGNKSK------GRSRAKRQQTRGGESQILQGAQPTVKEE--ETAPPSL------------------------------------------------------------VQGDAPSSPEVG---TPQESQEPASYGSPE--------LDVPCSVYDVDVEGSDVGAEGAVAGAKGSDAGVKGSVADAEDRSAHFSKVAAAIQSARRDPLTRKANVLIEFMMEKFKVKEPFTQADMLRVINKKYKVHFTEILRRISVRLELVFGLELKVVDPSSQSYMLVGKLGLST-EGSLSGSSGLPKTGLLMTLLGVIFMKGNHATEEEVWEFLKVVGIYPGKSHVIFG-EPQEFITKDLVEENYVVYQ--QVPGSEPPSYEFRWGPRAYAETTKMKVLEVIAKINNTSPSFFTSMYEEAMIDEANRAARRVTAVPGNVVDIRDVRAHRRVHRTSSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHM0-1", "uniprot_id": "A2AHM0_MOUSE", "id": "A2AHM0-1", "name": "", "aln": "MFSWKASKARSPLSPRYSLPGSTEVLTGCHSYLSRFLSASSFTSALSTVNMPRGQKSK------TRSRAKRQQSRR----EVPVVQPTAEEA----GSSPV------------------------------------------------------------DQSAGSSFPGGS---APQGVKTPGSFGAG-----------VSCTGSGIGGRN---------------------AAVLPDTKSSDGTQAGTSIQHTLKDPIMRKASVLIEFLLDKFKMKEAVTRSEMLAVVNKKYKEQFPEILRRTSARLELVFGLELKEIDPSTHSYLLVGKLGLST-EGSLSSNWGLPRTGLLMSVLGVIFMKGNRATEQEVWQFLHGVGVYAGKKHLIFG-EPEEFIR-DVVRENYLEYR--QVPGSDPPSYEFLWGPRAHAETTKMKVLEVLAKVNGTVPSAFPNLYQLALRDQAGGVPRRR-------VQGKGVHSKAPSQKSSNM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PSY2-1", "uniprot_id": "E9PSY2_RAT", "id": "E9PSY2-1", "name": "", "aln": "--------------------------------------------------MPRGQKSK------NRSRAKRQQARR----EVPEVQPTAEKA----GSS-V------------------------------------------------------------DESVGSSFPDGS---APQGVKTPGSFGAG-----------VSCAGSGIGVRN---------------------AAGFADQKSSDGTQAGASVQHTLKDPIMRKASVLIEFLLDKFKMKEAVTKSEMLAVVNKKYKEHFSEILRRTSARLELVFGLELKEIDASTQSYLLVGKLGLST-EGSLSSNWGLPKTGLLMSILGVIFMKGNRATVQEVWQFLNGVGVYAGKKHLIFG-EPEAFIT-DLVQENYLAYR--QVPSSDPPSYEFLWGPRAHAETTKMKVLEVLAKVNGTVPSAFPNLYQLALRDQAEGTKKK------------------SSRQGC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQR7-1", "uniprot_id": "MAGBI_MOUSE", "id": "Q8BQR7-1", "name": "Melanoma-associated antigen B18", "aln": "--------------------------------------------------MPRGQKSK------LRAREKRRQARA------KNAQEKEASPGPFYGCPHQ------------------------------------------------------------ASPVASMPTSPN---MPMGEQS-----------------TFSHSYTSTSDQN-------------------------LDEKSSDDS---EDTEDWCKDPINHKVVLLVQFLMEKYQKKEVITKADMLKYVIKTSKNHFNEILKRASEHMELAFGIDLKEVDPNRHCYALFNKLEHTF-DGVMGEE-KMPSSGLLMIVLGVIFMNDNCVSETEIWNVLSMMGVYANRKHFIYG-DPKKVITEDMVQLKYLEYQ--QVPNSNPPSFEFTWGPRACAEISKMKILEFWAKIHDTTPDSFPTLYEAALKDEEERAQARAVARAHTAAMASPYSRATVCSSSHTNI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V932-1", "uniprot_id": "G3V932_RAT", "id": "G3V932-1", "name": "", "aln": "--------------------------------------------------MPRGQKSK------LRAREKRRQARA------KNALEGQASPSPFFGCPHQ------------------------------------------------------------TIPVAGMPTPPN---MPMGAYS-----------------TYSDTYANTHAQN-------------------------LDEKSSDDS---EDVEDWCKDPINHKVVLLVQFLIEKYQKKEVITKADMLKSVIKTSKNHFNEILKRASEHMELAFGVDLKEVDPNRHCYALFNKLEHTF-DGVMGEE-KVPNSGLLMIVLGVIFMKDNCAPETEIWNVLSMMGVYANRKHFIYG-DPKKVITEDMVQLKYLEYR--QVPNSNPPSFEFMWGPRARAEISKMKILEFWAKIHDTTPDSFATLYKAALKDDEERAQARAAARARTATTASSYSRAMMHSSPPY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UW88-1", "uniprot_id": "G3UW88_MOUSE", "id": "G3UW88-1", "name": "", "aln": "--------------------------------------------------MPRGQKSK------LNARERRHRARN-YAQASEG----AEETVVATEESSP------------------------------------------------------------KS--------CGTSEMP----EKKSVSTVT--------VDLFSISDDSFIDLED--------------------------AEDLFRDYHTISH---QDILTQKVFVLVQILLKNYKTKQLTTIEDMMQVIDEEEMDDFPEILRKAAERLADVFAVELREVESSRRVYDLISKLKLPN-NGRVRAGQGFPKTGFLMTVLGIIFMNGNCAGEEDIWRTLRSMGIYSGKKHQIFG-EPRKLITQNFVKLKYVECR--QVANSKPPRYEFLWGPKAYAETNKMAILKFVAKVNEISPSYFKDLYKEALKDDQGKNQGNHNVSSAIHLKDRAFSFVMCPRLAFSNVEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVH9-1", "uniprot_id": "A0A8I5ZVH9_RAT", "id": "A0A8I5ZVH9-1", "name": "", "aln": "--------------------------------------------------MPRGQKSK------LNVRGTHRQAIN-YAQAFED----AKETVEPTEESSS------------------------------------------------------------ES--------GGTFEVP----EKQSVSTMN--------IDLFSILDGSSTDLDD--------------------------AESLFRNYHTINN---QDLLARKVLVLVQILLKNYKIKQLTTMEDMMQVIDKEEINDFPEMLRKAAERLADVFAVELREVESSRRVYDLISKLKLPN-NGRVRAGQGFPKTGFLMTVLGIIFMSGNCAREEDIWRTLRYMGVYSGKKHQIYG-EPRKLITQNFVKLKYLEYR--QVANSNPPQYEFLWGPKAYAETNKMTILKFVAKVNDIPPSCFPDLYEEALKDDQGKNQSNRNVSSAICPKARAFTFVMCPGFACFPAQV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GM54-1", "uniprot_id": "A0A8I6GM54_RAT", "id": "A0A8I6GM54-1", "name": "MAGE domain-containing protein", "aln": "--------------------------------------------------MPHDQKSK------LHSRENSYQAGG-GAQAYGDAEEIAEAAAEAAEESSA------------------------------------------------------------KSQSQPGAEYSRNHRAP----PKAKPSAKL--------ILSSSSSESDESSHEE--------------------------SEPSVQKDRPFLH---QDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPN-NGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFG-EPRKLMTQYLVKLKYLEYR--QVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GHH8-1", "uniprot_id": "A0A8I6GHH8_RAT", "id": "A0A8I6GHH8-1", "name": "", "aln": "--------------------------------------------------MLRSQKSK------PHAQEKHLQNQG-EAQACRDDQATAGETPKAARESSA------------------------------------------------------------TSQSQPKAKSSSTPKAS----QKAKPSAKL--------ILSSSSSESDESSHEE--------------------------SEPSVQKDRPFLH---QDLIARRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPN-NGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKQIYPGKKHRIFG-EPRKLMTQYLVKLKYLEYR--QVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9Q9-1", "uniprot_id": "A2A9Q9_MOUSE", "id": "A2A9Q9-1", "name": "", "aln": "--------------------------------------------------MPRGQKNKHHRNRLKNKKHNQEKVHP-QKDESQEKGHHKRDDFQDHKEAR-------------------------------------------------------------DNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGT-------------------YFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPN-KGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYR-EPRKLITQDFVKLKYLEYK--QISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A972-1", "uniprot_id": "D4A972_RAT", "id": "D4A972-1", "name": "", "aln": "--------------------------------------------------MPRGQKNK-HRKRLKNKKHNQEKGHP-EKDESQDKGHHKRDDSQDHKEAAQ------------------------------------------------------------DSAAIEEMPPCSSSSVPGKILETPPVSETNSDVGWPSCIPSPVTICSDDLDFDDEI-------------------YCQCGGNSLYSEYRTCQNIPCKHCLDMYVAFVEQYVLYKFKMKQLIVRKDLINVIEPKYQYRFNEISKRAFENIETVFGVSVIEIDSTNHIYDLVSNLKLPN-KGRVCAGRGLPKTGLLMTILAMIFMKGNSVSEEDIWKFLNFMQVYPGRKHFIYR-EPRKLITQDFVRLKYLEYG--QIPNSDPPCYQFQWGPKAYAETTKMKVLEFMAKGSGVEPSTFSVQYAEALKEENQKIKIRKWYPILAQKHCLGHGHHHIHKVMTPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AWU5-1", "uniprot_id": "A0A8I6AWU5_RAT", "id": "A0A8I6AWU5-1", "name": "", "aln": "--------------------------------------------------MPRGQKRK------LHAGKKCYQAGG-ETQDLQGAQALAEVEKSCPPPSSP------------------------------------------------------------HVGVTAHTKSASKLQTTSKVPQRALSTTES--------KGLSHTRPCKVAKYKIK-------------------------RKQQSSQTSPSTEKCPRSSLTSTVRLVVNYMMNMCKMKRPILKADVMKMVTNTHKVHIAEILRRASFNLEVLLGVDLKEADSMDS-YTLASKMNLPN-NGVLTTGRGFPKTGLLMNLLGVIFLKGNCATEESIWEFLNKMKIYDGKKHFIFG-EPRKLITQDLVKLKYLEYR--QVPNRSPTSYEFLWGPRSHAETSKMKILKFLAKINHIVPSAFQSRYDEALKDEEERSQAAATFGDTTINTK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWV4-1", "uniprot_id": "MAGBG_MOUSE", "id": "Q9CWV4-1", "name": "Melanoma-associated antigen B16", "aln": "---------------------------------------------------MSQSSEE-------CAADQGQTCEETQKLQVAAASIDVEEPCSSPHLMAT----------------------------------------------------------SLKDQTSEETQVSKDVEEPCSSSQLLMASDQDDSEDETASTSSDLQHPYDSSSESTED-----------------LDDQEVQGSPVIPPDQSDSTDLPVMTVDGKVDFLVNYMLYKYQVKEVMSMNDIMTLIVREDEDRFHEILMRASERMEMVFGLDVKEVDPINHCYALFIKLGLTY-DGMRNDEYSFPKTGLLILILGVVFMKGNRATEEEIWEVLNPMGIYAGMTHFMFG-DPRELITDEFVREQYLEYQ--PIANSDPIQYEYVWGLRAKAETSKMRVLEFVAKVHGSDPTVFLSQYEEALIEEEERTLTMLLEHADSSSTSGESSSDTSSNFSQV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY37-1", "uniprot_id": "MAGBG_RAT", "id": "Q6AY37-1", "name": "Melanoma-associated antigen B16", "aln": "---------------------------------------------------MSQKNPE-------YAADHDHTREEMQNLQVAPASSDVEEPCSSSHLMAS----------------------------------------------------------SLKGHTSEETQVPEDMEEPCSSSQLLTASNQEDPAYETPSTSRGLQHPYVSSSESAKG-----------------LGNKEMQGNSVIPPDQPD---LPVMTIDGKVNFLVNYMLYKYQVKEMMSMNDIMTLIVREDEHHFHEILMRASERMEMVFGLEVREVDPVNHFYALFIKLGLTY-DGMRADEYSFPKTGLLILILGVVFMKGNRATEEEIWEVLNPMGIYAGMNHFIFG-DPRELLTDDFVREQYLAYQ--PIANSDPIQYEYVWGPRAKAETSKMKVLEFVAKVHGSDPTVFPSQYEEALIEEEERTLAMILEQAGPSSASGESSSDMGSNVPHI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89012-1", "uniprot_id": "O89012_MOUSE", "id": "O89012-1", "name": "", "aln": "--------------------------------------------------MADSHNIQ-------YCNLQESAQAQQE---LDNDQETMVTSQEEEV-----------------------------------------------------------------TTTSNKVYGSGIPSPPQSPQRAYSP-------------CVALASIPDS---------------------------PSEEASIKGSEGLEDPLYLLHNAQNTKVYDLVDFLVLNYEMKAFPTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPFVHSYMLVTALGITY-DGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMLNNIGLCGGRNPYIHK-DPRKLISEEFVQEGYLEYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALQDEIDRTKAWILNRCSNFSD---LLTF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89009-1", "uniprot_id": "O89009_MOUSE", "id": "O89009-1", "name": "", "aln": "--------------------------------------------------MADFHNTQ-------YCNLQESAQAQQE---LDNDQETMETSEEEED-----------------------------------------------------------------TTTSNKVYGSGIPSPPQSPQRAYSP-------------CVALASIPDS---------------------------PSEEASIKGSEGLEDPLYLLHNAQNTKVYDLVDFLVLKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEIDPSVHSYILVTALGITY-DGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMLNNIGLYGGRNPYIHK-DPRKLISEEFVQEGYLEYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALQDEIDRTKAWILNRCSNSSD---LLTF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89006-1", "uniprot_id": "O89006_MOUSE", "id": "O89006-1", "name": "", "aln": "--------------------------------------------------MADSRNTQ-------YCSLQESAQAQQE---LDNDQETMETSEEEED-----------------------------------------------------------------TTTSNKVYGSGIPSPPQSPQRAYSP-------------CVALASIPDS---------------------------PSEEASIKGSGGLEDPLYLLHNAQNTKVYDLVDFLVLNYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPSVHSYILVTALGITY-DGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMVNNIGLCGGRDPYIHK-DPRKLISEEFVQEGCLKYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALRDEIYRTKAWILNRCSNFSD---LLTF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89010-1", "uniprot_id": "O89010_MOUSE", "id": "O89010-1", "name": "", "aln": "--------------------------------------------------MADFHNTQ-------YCNLEESAQAQQE---SDNDQETMETSEEEED-----------------------------------------------------------------TTTSNKVYGSAIPSPPQSPQRAYSP-------------CVALASIPDS---------------------------PSEEASIKGSGGLEDPLYLLHSAQNTKVYDLVDFLVLNYEMKAFPTKAEMLESIGREYEEYFPVIFSEASECLKMVFGLDMVEVDPSVHSYMLVTALGITY-DGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEVIWEMLNNIGLCGGRDPYIHK-DPRKLISEEFVQEGYLEYR--QVPNSDPPIYGFLWGPRALAETSKMKVLQFFASINKTHPRAYPEKYAEALRDEIERTKAWILSRCSNFSDHSSVLPFPF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "--------------------------------------------------MDDAHNIQ-------YSNLQDNAQAEQE---LDNAQATMAAAEEEEA-----------------------------------------------------------------TSTSKAEYGSGIPSPLQSPERACSP-------------SVALASIPVG---------------------------PSEEASIRQLEALEDPLYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKAEMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYVLVTALGITY-DGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDPYIHR-DPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQQMLRHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F2Z493-1", "uniprot_id": "F2Z493_MOUSE", "id": "F2Z493-1", "name": "", "aln": "--------------------------------------------------MENPDNTH-------YCSLQGSARSQRE---LDNVQATIAVVDEEEA-----------------------------------------------------------------TPTSKKVYSSGIPSPPQSPQRASSP-------------LVILASVPEG---------------------------PSEEASTNQVEEQEDPLCMLYNAQNIKLYELATFLFFKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECFKLVSGIGMIEVDPFVQSYILVPALGLTY-DGMLTDVQSKPKTGILIVVLGAIFTQGNCVSEEIIWKMLNNIGLYGGRHLYIHQ-DPRKFISEEFVQEGYLEYR--QVPNSDPPSYEFLWDPRAFAETTKMKVLEIFASITMTDPRAYTEKYAEALRDETERAQARIIQQIVLQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8H6-1", "uniprot_id": "Q4V8H6_RAT", "id": "Q4V8H6-1", "name": "", "aln": "--------------------------------------------------MEPTDNSQ-------NFNLWDIPQAQIEDRGPEDAQGPIAEAGEVEA-----------------------------------------------------------------IATISGDVSAGEE--PSSPQRASSP-------------PTAMGFIG-------------------------------EASFGNPLAGMPGTEFPVHGELNGKIVDLVRFLLVKFRRMEITSKEEMIHRTMRDYEEHYSVIFSKAAECMKLIFGVDMMEVDPFVHSYFLYPALGITY-DGMLHGVVGVPKTGLVIIVLCIIFIEDNCVSEEVFWHVMNSLGMYAGVDHFIFG-DPRSLITEDFVQEGYVEYR--QVPNSHPPRFEFLWGPRAYAETTKMKILEFYASIVRQDPRSYPEKYAEALREEQERA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AMW4-1", "uniprot_id": "A2AMW4_MOUSE", "id": "A2AMW4-1", "name": "", "aln": "--------------------------------------------------MPRPRKRR-------RCMVEGQPEAQ-------SVAVTMEEDSSSSSS-----------------------------------------------------TYSSSFPSSFSSTSSSYALTSGNSEEGCAASRASSPHSPPGAGS----SCTAMISSPRSQV----------------------SADSEGEDSPGSSQALPCGTSLSTGEIDVKVDELVKYLLLKYLMQEPVSKAEILSNIIRNYQDHFAVIFREALECMQLVFGLELKEIDPASHTYILTIALELTY-DGMMTDVQGIPKTGLLIMVLSIIFMEGNCVSEDMVWSILNNIGLYAGNEHFIYG-EPRKLITDNFVQEGYLEYR--HVPGSNPPFYEFLWGPRAYAETTKMKILTFLTSINGSDPRSFPVWYAEALRDEEQQE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JXU3-1", "uniprot_id": "A0A0G2JXU3_RAT", "id": "A0A0G2JXU3-1", "name": "", "aln": "--------------------------------------------------MPRPRKRR-------RCMVEGQPEGQNETEGQMSVAVSTEEDSSSSS------------------------------------------------------TSSSSFPFSFSSTSSSYSQTSGNSEEGCAASRAFS-------------SCTAMVSSPCSQV----------------------SADPEGEESPGSSQTLLCGASLSTGEIDVKVDELVKYLLFKYLMKEPVSKAEILSNIIKNYQDHFPVIFREASECMQLVFGLELKEIDPAGHTYILAIALELTY-DGMMTDIQGIPKTGLLIMVLSIIFMEGNCIREDMVWGVLNNIGLYAGSEHFIYG-EPRKLITDDFVQEGYLEYR--QVPGSHPPSYEFLWGPRAYAETTKMKILTFLTSINGSDPRSYPVWYAEALRDEEERE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LUV1-1", "uniprot_id": "F1LUV1_RAT", "id": "F1LUV1-1", "name": "", "aln": "---------------------------MPYYPYFSLEKVFQDAFEIYILPDEEQEDDE-------EEMEEEGEEIEEEEEEMEEEEEEEEEEGEEEDYDDEEEEEGTGEEEEIEVEEVEEELEEEEIEGDVEEVEEEEEVEQEEYEEDIEEEEWETIDGDTVSFTLSATLKISLPSCPSPPSTFSSHPLIWGNPNGMEESVAWMMNISQSHQSLYTF-----------------TSCSNLDEEYSSQEEESLNTFSWRKRQNQKVTELVNLLILKYRKKEPIKKVEMLTVVTEDYENQFPIIFEEASKCLEMIFGIDIKENDAVSSSYVLTNTLGLTY-EDTMTDNQRLPRNGFLIVILGVIFIEGNCASEESMWEFLNMMGIYDGKEHFIYG-EPREFLTIDLVHQNYLKYQ--QVPKSYPPRYQFLWGPRAYSETTKMKVLEFLAKLTSRAPTHFSSLYSEAFRDEEGRAGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPR8-1", "uniprot_id": "NSE3_MOUSE", "id": "Q9CPR8-1", "name": "Non-structural maintenance of chromosomes element 3 homolog", "aln": "--------------------------------------------------MLQKPRGR---------GRPSTQAD---------------------------------------------------------------------------------------PERDWGG--AGEE-----GPSTS-----------------------RAAGG--------------------------SSQGSRASLSAPTVGPRTQKQLELKVAELVQFLLIKDQKKIPIKRTDILKHVVGDYRDVYPNLLKLAAERLQYVFGYKLVELEPKSHSYILINMLEPVEADAEMRGDQGTPISGLLMIVLGLIFMKGNTITETEVWDFLRRLGVYPTKKHLIFG-DPKKLITEDFVRQRYLEYR--RIPHTDPVDYELQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPTQYCEALADE----ESRARPATASAPATSS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K397-1", "uniprot_id": "A0A0G2K397_RAT", "id": "A0A0G2K397-1", "name": "", "aln": "--------------------------------------------------MLQKTRSR---------SHPGAQLG---------------------------------------------------------------------------------------GGSGCCPSVSGEIPSVAGHPDAS-----------------------LDTLG--------------------------ARSLSSQAQATSTRELRTQKQLELKVAELVQFLLIKDQKKIPIKRSGILKHVIRDYKDIFPDLLKLAAERLHYVFGYKLVELEPKSNAYILINALEPVEEDGELRGYQGTPTTGLLMIILGLIFMNGHSIPEADVWDFLRRLGVCPTKKHSVFG-DPKKLITEDFVRQRYLESR--RIPHTDPVDCELQWGPRANLETSKMKVLKFVAKIHNQDPKDWPTQYCEALADE----QRRLRPE-PSGPVPTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25233-1", "uniprot_id": "NECD_MOUSE", "id": "P25233-1", "name": "Necdin", "aln": "--------------------------------------------------MSEQSKDL---------SDPNFAAEVPDCEMQDSDAVPVGIPPPASL-----------------------------------------------------------------AANLAGPPCAPEGPMAAQQASPPPEERIE---------DVDPKILQQAAEE--------------------------GRAHQPQSPARPIPAPPAPAQLVQKAHELMWYVLVKDQKRMVLWFPDMVKEVMGSYKKWCRSILRRTSVILARVFGLHLRLTNLHTMEFALVKALSPEELDRVALNNR-MPMTGLLLMILSLIYVKGRGAREGAVWNVLRILGLRPWKKHSTFG-DVRKIITEEFVQQNYLKYQ--RVPHIEPPEYEFFWGSRANREITKMQIMEFLARVFKKDPQAWPSRYREALEQARALREANLAAQAPRSSVSED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7A4-1", "uniprot_id": "G3V7A4_RAT", "id": "G3V7A4-1", "name": "Necdin", "aln": "--------------------------------------------------MSEQSKDL---------SDPNFAAEDPDTEMQVSDAVPVGVPPPAPL-----------------------------------------------------------------AANLSGPSCAPEGPMAAPQASPPPAERFE---------EVDPKILQQAAEE--------------------------GRAHQPQSPARPIPAPPAPAQLVQKAHELMWYVLVKDQKRMVLWFPDMVKEVMGSYKKWCRSILRRTSVILARVFGLHLRLTNLHTMEFALVKALSPEELDRVALNNR-MPMTGLLLMILSLIYVKGRGAREGAVWNVLRILGLRPWKKHSTFG-DVRKIITEEFVQQNYLKYQ--RVPHIEPPEYEFFWGPRANREITKMQIMEFLARVFKKDPQ------------------ANLVAQAPRSSVSED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "--------------------------------------------------MAS--TSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGD--KSELKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVAS--IHELTPAQRPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "--------------------------------------------------MSSIDNDS---------DVDLTEDLAVAKIVKENPVARKMVRYILSRGESQ-------------------------------------------------------------NSIITRNKLQSVIHEAAREENIAKP-------------SFSKMFMDINAILYN------------------------VYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLN----NVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDR---------DLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .: :* :: . : : . . : . . :: * : ", "identical_positions": 2, "similar_positions": 19, "identity": "0.28%" }, { "cls_id": "homologset.agr.SGD:S000002697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAU4-1", "uniprot_id": "D4AAU4_RAT", "id": "D4AAU4-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "aln": "MLAPPRPAPPPFSTLLLFFPFPLPLPPPGGGSFPRESSARGRARCVTSLPAGRHLARLRPASDSGVVVVRAWGRVGCGGEAATRAATLSSPQLHGVGRRERGFGGMSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKP--NRKLTFLYLANDVIQNSK-RKGPEFTKDFAPVIVEAFKHVSSETD-ESCKKHLGRVLSIWEERSVYENDVLEQLKHALYG--------------------------------------------DKKTR-KRTYEQIK---------VDE---NENCSSLGSPSEP-----PQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKIT-DKESGERLS---KMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRARIQSLPDLS---------RLPNVTGSHMHLPFAGDIYSED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDS4-1", "uniprot_id": "RPR1A_MOUSE", "id": "Q8VDS4-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "aln": "---------------------------------------------------------------------------------------------------------MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKP--NRKLTFLYLANDVIQNSK-RKGPEFTKDFAPVIVEAFKHVSSETD-ESCKKHLGRVLSIWEERSVYENDVLEQLKHALYG--------------------------------------------DKKAR-KRTYEQIK---------VDE---NENCSSLGSPSEP-----PQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKIT-DKESGERLS---KMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRARIQSLPDLS---------RLPNVTGSHMHLPFAGDIYSED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P16-1", "uniprot_id": "RPR1A_HUMAN", "id": "Q96P16-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "aln": "---------------------------------------------------------------------------------------------------------MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKP--NRKLTFLYLANDVIQNSK-RKGPEFTKDFAPVIVEAFKHVSSETD-ESCKKHLGRVLSIWEERSVYENDVLEQLKQALYG--------------------------------------------DKKPR-KRTYEQIK---------VDE---NENCSSLGSPSEP-----PQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKIT-DKESGERLS---KMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLS---------RLPNVTGSHMHLPFAGDIYSED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CSU0-1", "uniprot_id": "RPR1B_MOUSE", "id": "Q9CSU0-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1B", "aln": "---------------------------------------------------------------------------------------------------------MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKS--NRKLTFLYLANDVIQNSK-RKGPEFTREFESVLVDAFSHVAREAD-EGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAA----------------------------------EEKKSL-KRTFQQIQ---------EEE---DDDYPGSYSPQDP-SAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKIT-DKEAAERLS---KTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKEVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLS---------LLPNVTGGLAPLPSAGDLFSTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQG5-1", "uniprot_id": "RPR1B_HUMAN", "id": "Q9NQG5-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1B", "aln": "---------------------------------------------------------------------------------------------------------MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKS--NRKLTFLYLANDVIQNSK-RKGPEFTREFESVLVDAFSHVAREAD-EGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT----------------------------------EEKKSL-KRTFQQIQ---------EEE---DDDYPGSYSPQDP-SAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKIT-DKEAAERLS---KTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLS---------LLPNVTGGLAPLPSAGDLFSTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9C1-1", "uniprot_id": "A0A8M2B9C1_DANRE", "id": "A0A8M2B9C1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MSSFSESALEKKLSELSNSQQSVQTLSLWIIHHRKHAALIVRVWHRELKKAKS--SRKLTFLYLANDVIQNSK-KKGPEFAKDFEGVLIDACSHVARDGD-DGCKKQMDRLLTIWQERNLYRPDFIQQLKLTIDDSESPKHKTAG-----------------------------QRNADDRKNL-KRSYQKVQ---------EEEEEEDDDYRGHYSPRETDAAAPQLTEDLVKALQDLENAASGDAAVRQKIASLPQEVQDVSLLEKITADKQAADKLS---KTVDEACLLLAEYNGRLAAELEDRRQLARMLTEYIQSQKDALNEREKKLEEYKQKLARVTQVRKELKSHIQSLPDLS---------LLPNVTGGLAPLPSAGDLFSTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W039-1", "uniprot_id": "Q9W039_DROME", "id": "Q9W039-1", "name": "CID domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------MSAFTDSALLKKLAELNSSQQSIQTLSLWLIHHRKHSAAIVRTWQRELENVPE--PKKLTFMYLANDVIQNSK-KKGPEYGKEYSLVLGKVFAHIGEKCNSDKLLGSLGRILNIWLERGVYDPKTIADWRSRLHKEAPGSSSSSNGKTNGDSEKPEKEKDHGGSGKPEKSERREKRKHEDRHSKSKRSRHHVQGSSANSAPPTEEVVSVEPENGHTPPYLP-LGEPPEPEELIRALTSIENSASSDAVVRERIAKLPQEISEISCISKLE-DKDKAKELA---IQVNEAVDLLNDYNARLAAEMEERSKLATMLRDFQAEQKELLSQAEQRLDEHKKKLAKMLGLQKEIHDHLSNLPDLT---------RLPDVTGGLAPLPSAGDLFNALH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5VT52-1", "uniprot_id": "RPRD2_HUMAN", "id": "Q5VT52-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "aln": "---------------------------------------------------------------------------------------MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAY--PHRLNLFYLANDVIQNCK-RKN---AIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTT------------------------------------------FKTQKQLKENLNKQP---------NKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLK-DKTGGKKFS---KEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTS-LSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JTD1-1", "uniprot_id": "A0A0G2JTD1_RAT", "id": "A0A0G2JTD1-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "aln": "---------------------------------------------------------------------------------------MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTY--PHRLNLFYLANDVIQNCK-RKN---AIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREALSTT------------------------------------------FKTQKQLKENLNKQP---------NKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLMYKRSEDQIELKEKQLSTMRVDVCSTETLKCLK-DKTGGKKFS---KEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPVEKPAVSTGVVTKSTENISKTSPCAPPSVPTTAAPPLPKPLNTSLLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSASRPSPGTPTSPSSLSSGLKTPAPATTPSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTAASPASTTGSAVKGRNLLSNTQSFISKSFNYSPNSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFTGTHNTSPAAPPTEVAMCQSSEVSKPKPESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSEGHSSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSIRSPPAGGDESYPQEPPSSVSTYRPFGLGGGSPYKQSSSAVERPSSLMDSSQEKLFPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDATEYQPILSSYNHRAQEFGGKSAFPPSVRALLDSSENCDRLSSPPGLFGAFSIRGSEPGSERSPSPSKNDSFFTPDSNHSGLSQSTAGHLTLPQTQYPDSPHSVPHRSVFSSQNTLAAPAGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQTPNKGTSSDGVSLSNLTQPSLPTTDQQQ-EEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNAANRRMSGEPIQTVESVRVPGKGNRGHGREVSRVGWFDLSTPGSSFDNGPSSASELASLGGGGSGGLTGFKTTPYKERAPQFQESVTSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPAPPKDHGGIFSREAPTHLPSVDLSNPFTKEASLAHAGPPPPPGEHSGVPFPPPPPPPPPGELSS-GGSGVPFATPPPPPPPVDHSGVVPFPTPPLPEHGVTGAVAVFPKDHSSLLQGTMAEHFGVLTGPR--------DLNGPGLSRARESLSLPSHPLDHLGPALGGGGGGNS-SSSGLPLGPAHRDAISRSGVVFRSPRPDFRPREAFLGRDPFHSLKRPRPPFVRGPPFFAPKRPFFPPRRSYISEDGAPEWPMTRVSCPPQTELWAFLEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "X2JAA3-1", "uniprot_id": "X2JAA3_DROME", "id": "X2JAA3-1", "name": "CID domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------MTETFDEELFETRLEALKDTQEGIQQMSNWCLQHRSNHKKIIQCWLNVFKRVRV--DHRLVLFYLANDVIQYSK-RKR----YEFVECWATALQRATTMVRDERVKDKILRIFKIWEQREIYNEEYLSDLSGLLNIAPP------------------------------------------KKSQVDVS------------------------------------DEFQNATLIAQVRECVELAEITDKSMQKLPKP--PTFEIEVIKQQLKDKSHSGNIE---KEVERCVAFINAYNKNLQNEIKSRKAVLASIEAAKKFYEHQGKEVKVVASAYKSFGTRIKIVKRKLDETIPNLASPIP---------SPDVNAPSPERDADLQLPEENNIPLNLFGGSINGFTSYLDGGKLP--------FDINDFKRDSKDRGSAIEVIGSRSDDEAYVPSANFYKPEPISSADSSSIPGLGGSAVYTPDAPLFGSNSQDQYVPPPPSHLYGDNGNGGSSGGPSDQYTPAPMPPPPLPPSLGPSSGSADDFNSTWNMSMSWTPLDSSLNSSGASSSSYANQSTPNSPPHFDRKASSTAAPIEYNELLHTN----PAALGAEDVDHRTLQLPPAFEFGAKLGLSKDKSRQLVDIDHRNLISLTGSPGGAEKDFTGGDVDYRIVPSPNDEGIMAPPGNNYAKSKTCSPLKSNASSSSESDRVDGATRYDPADMVIDMDMSD----------------------------DDIDESLREPKEDNGDAEIDANGALTPSRPVLLETPPDFINPWDANNSFMGPPLPDEEDQ-------------------------------------------------QQHHEQQQNQQQELQQHHQHQQHQQQQPWNQMNRMQMGGGGAPPPPRPPYGQPFPPFQRFPGPPMNGPDGMQRGRGRGRGWNGPGPGPFRPPYQRMPGPGFDGPGPGPRPFFPRGGGPGGPMRGRGRMRDLLKSNFSDFCGLKLYTIVIVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05543-1", "uniprot_id": "RT103_YEAST", "id": "Q05543-1", "name": "Regulator of Ty1 transposition protein 103", "aln": "----------------------------------------------------------------------------------------------------------MPFSSEQFTTKLNTLEDSQESISSASKWLLLQYRDAPKVAEMWKEYMLRPSVNTRRKLLGLYLMNHVVQQAKGQKIIQFQDSFGKVAAEVLGRINQEFP-RDLKKKLSRVVNILKERNIFSKQVVNDIERSLKTE-------------------------------------------SSPVEALVLPQKLK-------------DFAKDYEKLVKMHHNVCAMKMRFDKSSDELDPSSSVYEENFKTISKIGNMAKDIINESILKRESGIHKLQSTLDDEKRHLDEEQNMLSEIEFVLSAKDPSRLNKNVDEDNIIPTYEVGDGDDDDDDGDNDDDDDDDDDDKNYDDRSNDSNYGVTN-------ISTTDKKNEVVEKTDSEHKNSTHNPSDNQFGMKRT--------------------HDMIGHDDANDIPEKKVHLDSKTSEDGTFNSEDGHYELDIEGHVGAQTDEGVENSGGVSSSIQDLLSKLAN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : .: :.:. * * : : . : * . : . ::* :** *.*:* .* :* : . . : *:..* :* :: . : : : . .:: . . . :. : : .: : * : . : : . . :. . . .. . . ", "identical_positions": 15, "similar_positions": 67, "identity": "0.91%" }, { "cls_id": "homologset.agr.SGD:S000002700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBG7-1", "uniprot_id": "SRPRA_MOUSE", "id": "Q9DBG7-1", "name": "Signal recognition particle receptor subunit alpha", "aln": "MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQER-GGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESS--KIRAPTTMKKFEDSEKAKKPVRSMIETRGEKTKEKAKNNKKRGAKKEGSDGTLATSKTAPAEKSGLSAGPENG-ELSKEELIRRKREEFIQKHGKGLDKSSKSTKSDTPKEKGKKAPRVWELGG-CANKEVLDYSTPTTNGTPEAALSEDIN--LIRGTGPGGQLQDLDCSS---SDDEGATQN----TKPSATKGTLGGMFGMLKG-LVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQR------PYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLTALHPPEKHGG---------RTMVQLFEKGYG--KDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08240-1", "uniprot_id": "SRPRA_HUMAN", "id": "P08240-1", "name": "Signal recognition particle receptor subunit alpha", "aln": "MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQER-GGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESS--KIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGG-CANKEVLDYSTPTTNGTPEAALSEDIN--LIRGTGSGGQLQDLDCSS---SDDEGAAQNS---TKPSATKGTLGGMFGMLKG-LVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQR------PYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGG---------RTMVQLFEKGYG--KDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9U5L1-1", "uniprot_id": "SRPRA_DROME", "id": "Q9U5L1-1", "name": "Signal recognition particle receptor subunit alpha homolog", "aln": "MLDFVVIFTKGGVVLWHSNASGNSFASCINSLIRGVILEERNTEAKYYEEDHLAVQFKLDNELDLVYAAIFQKVIKLNYLDGFLADMQAAFKEKYG-DIR-------LGDDYDFDREYRRVLSAAEEASAKQVKAPKTMRSYNESQKSKKTVASMIQD-DKKPVEKRVN----------------IQEAPPPSKS-QPSSPPTG--SPMDKIIMEKRRKLREKLTPTKKTSPSDSKSSKPEKAGKK-PRVWDLGGNSKDAALLDRSR----DSPDDVQYQNIN--SELVGTMQGVIRDLDVESEDEADNEDASSEGEAEEQVQSKKGKRGGLLSYFKG-IVGAKTMSLADLQPALEKMRDHLISKNVASEIAAKLCDSVAASLDGKQMGTFDSIASQVKEALTESLVRILSPKRRIDIIRDALESKRNGR------PYTIIFCGVNGVGKSTNLAKICFWLIENDFNVLIAACDTFRAGAVEQLRTHTRHLNALHPAAKHDG---------RNMVQLYEKGYG--KDAAGIAMEAIKFAHDTRVDVVLVDTAGRMQDNEPLMRSLSKLIKVNNPDLVLFVGEALVGNEAVDQLVKFNQSLADYSSNENPHIIDGIVLTKFDTIDDKVGAAISMTYITGQPIVFVGTGQTYADLKAINVNAVVNSLMK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32916-1", "uniprot_id": "SRPR_YEAST", "id": "P32916-1", "name": "Signal recognition particle receptor subunit alpha homolog", "aln": "MFDQLAVFTPQGQVLYQYNCLGKKFSEIQINSFISQLITSP-VTRKESVANANTDGFDFN-------------LLTINSEHKNSPSFNALFYLNKQPELYFVVTFAEQTLELNQETQQTLALVLKLWNS-LHLSESILKNRQGQNEKNKHNYVDILQGIEDDLKKFEQYFR------------IKYEESIKQDHINPDNFTKNG------SVPQSHNKNTKKKLRDTKGKKQSTGNVGSGRKWGRDGGMLDEMNH--EDAAKLDFSSSNSHNSSQVALDSTINKDSFGDRTEGGDFLIKEIDDLLSSHKDEITSGN-----EAKNSGYVSTAFGFLQKHVLGNKTINESDLKSVLEKLTQQLITKNVAPEAADYLTQQVSHDLVGSKTANWTSVENTARESLTKALTQILTPGVSVDLLREIQSKRSKKDEEGKCDPYVFSIVGVNGVGKSTNLSKLAFWLLQNNFKVLIVACDTFRSGAVEQLRVHVENLAQLMDDSHVRGSKNKRGKTGNDYVELFEAGYGGSDLVTKIAKQAIKYSRDQNFDIVLMDTAGRRHNDPTLMSPLKSFADQAKPDKIIMVGEALVGTDSVQQAKNFNDAFGKG------RNLDFFIISKCDTVGEMLGTMVNMVYATGIPILFVGVGQTYTDLRTLSVKWAVNTLMS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ..:*: * **: : ... : : . :: . : : : :.:: ::.:. . ..: * : :: : : : * * :: . . :.:* *: .::: .. : .:. .: . .* .: :..: :* .. . : . .: *:. : ::. : ** * .:.: . . ** * : : .. :..: :. ..* . :. :: ::* *::. *::..*:*: ::**:****.: * * :.*: .* *. ..: :: . .:::* ::*.:** * :*::*: . : . **.. : ***********:*:.***::*.*.***.******:*******.*...* * : * . *:*:* *** . .: ** :** :::: .*:**:***** ::: .** .* .: .** :::*******.::*:* :** ::.. : :* ::::* **:.: :*: :.*.* *. **:***.**** **:::..: .* :**. ", "identical_positions": 139, "similar_positions": 223, "identity": "20.81%" }, { "cls_id": "homologset.agr.SGD:S000002701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6W6-1", "uniprot_id": "A0A0G2K6W6_RAT", "id": "A0A0G2K6W6-1", "name": "DIS3-like exonuclease 2", "aln": "------------------------------------------------------------------------------------------------MNHPDYKLNLQSPGTPRGVSSVVGPNAVGASPGDKKSKNKSMRGKKKS-IFETYMSKEDVSEGLKKGTLIQGVLRINPKKFHEAFIPSPDGDRDIFIDG-----------------------------------------------------VVARN---RALNGDLVVVKLLPEDQWKPRITL----------------------SLPGVLGLQGVKPESNDKETEATNETDISEESCGHHLLQKSPKGWN-------------------------------------------GPDVIIEAQFDDSDSEDR-----------------------------HGNTS-GLVDGMKKLSVCT---------------------PDKGKEDSSAPVMKDENTPKSQDTRALSE------------------------KSLQKS------------------AKVVYILEKKHSRAATGILKLLADKNSD--------LFKKYALFSPSDHRVPRIYVPLKDCPQDFMTRPKDYANTLFICRIIDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQS--LPWTIPPEEVGKRRDLRKDCIFTIDPSTAR--DLDDALSCRQLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEW--FGRTIIRSCTKLSYDHAQSMIENPTEKIPKEELPPISPEHSIEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTNTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQAQFRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDALQKQADHCNDRRMASKRVQELSIGLFFSILVKES----GPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRSYHFQKVGKKPELTLVWEPD---------------------------------DLEEEPIQQVITIFSLVDVVLQAEATALKYSAILKRPGPEHSLGLEKESDE---EPED--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI75-1", "uniprot_id": "DI3L2_MOUSE", "id": "Q8CI75-1", "name": "DIS3-like exonuclease 2", "aln": "------------------------------------------------------------------------------------------------MNHPDYKLNLRSPGTPRGVSSVVGPSAVGASPGDKKSKNKSMRGKKKS-IFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDGDRDIFIDG-----------------------------------------------------VVARN---RALNGDLVVVKLLPEDQWK------------------------------------AVKPESNDKEIEATYEADIPEEGCGHHPLQQSRKGWS-------------------------------------------GPDVIIEAQFDDSDSEDR-----------------------------HGNTS-GLVDGVKKLSIST---------------------PDRGKEDSSTPVMKDENTPIPQDTRGLSE------------------------KSLQKS------------------AKVVYILEKKHSRAATGILKLLADKNSD--------LFKKYALFSPSDHRVPRIYVPLKDCPQDFMTRPKDFANTLFICRIIDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQS--LPWTIPPDEVGKRRDLRKDCIFTIDPSTAR--DLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEW--FGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQEQFRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKES----GPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRSYSFQKVGKKPELTLVWEPD---------------------------------DLEEEPTQQVITIFSLVDVVLQAEATALKYSAILKRPG------LEKASDE---EPED--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYB7-1", "uniprot_id": "DI3L2_HUMAN", "id": "Q8IYB7-1", "name": "DIS3-like exonuclease 2", "aln": "------------------------------------------------------------------------------------------------MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKS-IFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDGDRDIFIDG-----------------------------------------------------VVARN---RALNGDLVVVKLLPEEHWK------------------------------------VVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYND------------------------------------------SPDVIVEAQFDGSDSEDG-----------------------------HGITQNVLVDGVKKLSVCV---------------------SEKGREDGDAPVTKDETTCISQDTRALSE------------------------KSLQRS------------------AKVVYILEKKHSRAATGFLKLLADKNSE--------LFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQG--LPWTIPPEEFSKRRDLRKDCIFTIDPSTAR--DLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEW--FGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAFPEQALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSGLLQDPAQFRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQELSTSLFFAVLVKES----GPLESEAMVMGILKQAFDVLVLRYGVQKRIYCNALALRSHHFQKVGKKPELTLVWEPE---------------------------------DMEQEPAQQVITIFSLVEVVLQAESTALKYSAILKRPGTQGHLGPEKEEEESDGEPEDSSTS----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRJ7-1", "uniprot_id": "Q8IRJ7_DROME", "id": "Q8IRJ7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MPYPLYPAHSQVMSETSSVNVDADRDCRRIEGLRQRSQRLAARLQQMQREMESNASSKDLSANNAVIPLQPLMRWAEPRPHPNQSQPSARSNSRQAIPYGVPVSTPAPVAMQLPYHVAFASYQATMQIPCLQPLSHLHVVSSPS------HRLIAKKKSKRALRNEVEALQDMVKHLSHLSPDVNAYACQLIRKN-------EILSQLEWSQTRSEAHPQQVGYQGRHRHDSEVSATNNGSHVQQQPKLGRRQRNSKKNDGSGSNGTQSQKTELEAMRSYINKIVQRHVGMDHQLSEDLIFKGNFSDLEAHAQRLVAAGYGRIVEEEIRVNRKNNRQAFIIMSTDREALERDGIVLLPVARRYAFDGDKVRAFVL-NPGAQGSSKTAEPSSGEISGGKPSLSLADGEELSD------------------------DTESQGSESDTDNVVVISSDNCPKAFVIAITKRTELRQIVGTISFTNPTKLC--------DDQLFYKFRPYDLRVPMVYVPKDACAAHIGNKQQIDVSGLLYLAHILETDCNGHCIAELIQPVGRVGNLDDELKAILFHNGLRDIKPFEQRFIDIYSQ--PPPPISQEDLRQRKDLRKMCIFTIDPMTAR--DLDDAVSIEKLGDNEYEIGVHISDVSHFLIEDNELDNIVKERSTSIYLANEVIHMLPQSLCMR-CSLLPGQDKFAFSVFWRMNGKGVMLQKKPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTILNGFNPDDIRNRVLWLHDIASSIRKTRLDNGALTINNAKLRFLLDPITGEPLSFEVEKQREANRLIEEFMLLANQAVARFIHDSFPDIAVLRNHPPPLIKSLKALREKLLALGFELDYSSSKALQESMVRLCNEAPNPVAMNACLSQLLMKPMARATYFCSEGKSEPADLWHYALSIPIYTHFTSPIRRYPDILVHRLLAAALKYCTPPKRTPDDLHTLTKLANERKYNAKKAGEDSGNLYFKRYVHNK----QGIYMRAVVIEIFQHMMNVVTLESGHVISINYKMQKVLVDTHG----VPNYILIAERN---------------------------------LKQSPRKLQLLSVVPICLIIWDQKLTGFLKMEEQI-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24276-1", "uniprot_id": "SSD1_YEAST", "id": "P24276-1", "name": "Protein SSD1", "aln": "MSKNSNVNNNRSQEPNNMFVQTTGGGKNAPKQIHVAHRRSQSELTNLMIEQFTLQKQLEQVQAQQQQLMAQQQQLAQQTGQYLSGNSGSNNHFTPQPPHPHYNSNGNSPGMSAGGSRSRTHSRNNSGYYHNSYDNNNNSNNPGSNSHRKTSSQSSIYGHSRRHSLGLNEAKKAAAEEQAKRISGGEAGVTVKIDSVQADSGSNSTTEQSDFKFPPPPNAHQGHRRATSNLSPPSFKFPPNSHGDNDDEFIATSSTHRRSKTRNNEYSPGINSNWRNQSQQPQQQLSPFRHRGSNSRDYNSFNTLEPPAIFQQGHKHRASNSSVHSFSSQGNNNGGGRKSLFAPYLPQANIPELIQEGRLVAG---------------ILRVNKKNRSDAWVSTDGALDADIYICGSKDRNRALEGDLVAVELLVVDDVWESKKEKEEKKRRKDASMQHDLIPLNSSDDYHNDASVTAATSNNFLSSPSSSDSLSKDDLSVRRKRSSTINNDSDSLSSPTKSGVRRRSSLKQRPTQKKNDDVEVEGQSLLLVEEEEINDKYKPLYAGHVVAVLDRIPGQLFSGTLGLLRPSQQANSDNNKPPQSPKIAWFKPTDKKVPLIAIPTELAPKDFVENADKYSEKLFVASIKRWPITSLHPFGILVSELGDIHDPDTEIDSILRDNNFLSNEYLDQKNPQKEKPSFQPLPLTAESLEYRRNFTDTNEYNIFAISELGWVSEFALHVRNNGNGTLELGCHVVDVTSHIEEGSSVDRRARKRSSAVFMPQKLVNLLPQSFNDE-LSLAPGKESATLSVVYTLDSSTLRIKST-WVGESTISPSNILSLEQLDEKLSTGSPTSYLSTVQEIARSFYARRINDPEATLLPTLSLLES---------LDDEKVKVDLN----------ILDRTLGFVVINEIKRKVNSTVAEKIYTKLGDLALLRRQMQPIATKMASFRKKIQNFGYNFDTNTADELIKGVLKIKDDD-----VRVGIEILLFKTMPRARYFIAG-KVDPDQYGHYALNLPIYTHFTAPMRRYADHVVHRQLKAVIHD-TPYTEDMEALKITSEYCNFKKDCAYQAQEQAIHLLLCKTINDMGNTTGQLLTMATVLQVYESSFDVFIPEFGIEKRVHGDQLPLIKAEFDGTNRVLELHWQPGVDSATFIPADEKNPKSYRNSIKNKFRSTAAEIANIELDKEAESEPLISDPLSKELSDLHLTVPNLRLPSASDNKQNALEKFISTTETRIENDNYIQEIHELQKIPILLRAEVGMALPCLTVRALNPFMKRV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : . . . . . : .. : . .. *...: .* . .. .. * .:* . * . . : : : . . . .:: * : . . * ...:: :. . ..: * . .. . .. : . : * **. . :. . *: : .: : * : : .: * * * :** : :* . .. .: . . . *: . :. * . :* : : * ..** . .. . .: . * .:. :.. *::: . :.* . : : *: . :. ::* *: **: .: *...:*. . :*:::::: :::: :**: : . ** * :. ::**.: : . :.. . .: * ... :: :: :. :.. . . . * . :.: * . :. ::: *: . *: : . . :::*: .* :**. *. : : *:**.: * : : : :* .* .:: * :.: . .: . : : :.* * ** : : : ****.:*:*****:*:**:.* :*** * *.: : *: :. .* :: : :. * : * : ::: : * *: : : ::*. . * : . : . : : :. : : .: : : . * ", "identical_positions": 94, "similar_positions": 277, "identity": "7.27%" }, { "cls_id": "homologset.agr.SGD:S000002702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHN6-1", "uniprot_id": "SGPL1_RAT", "id": "Q8CHN6-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLKLKDFEPYLEILEAYSTKAKNYVNGYCTKYEPWQ------LIAGSVLCTLLVVWVYELIFQPESLWSR----FKNKLFRLIRKMPFIGRKIQQQLTKAKKDLVKNMPFLKLDKDYVKTLPAQGLSTAEVLERLKEY-SSMDVF-WQEGKASGAVYSGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVAQK-KNMEVDVRAMKRAISRNTAMLVCSAPQFPHGVIDPIPEVAKLAVKYKIPFHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRKYQFFVDADWQGGIYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKMVAEISSVFLDSLYSTDPVTQGNQMNGSPKPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0X7-1", "uniprot_id": "SGPL1_MOUSE", "id": "Q8R0X7-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPGTDLLKLKDFEPYLEILESYSTKAKNYVNGYCTKYEPWQ------LIAWSVLCTLLIVWVYELIFQPESLWSR----FKKKLFKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTLPAQGMGTAEVLERLKEY-SSMDGS-WQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVALK-KNMEVDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLDCLYTTDPVTQGNQMNGSPKPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95470-1", "uniprot_id": "SGPL1_HUMAN", "id": "O95470-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLMLKAFEPYLEILEVYSTKAKNYVNGHCTKYEPWQ------LIAWSVVWTLLIVWGYEFVFQPESLWSR----FKKKCFKLTRKMPIIGRKIQDKLNKTKDDISKNMSFLKVDKEYVKALPSQGLSSSAVLEKLKEY-SSMDAF-WQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDS-CGCVTSGGTESILMACKAYRDLAFE-KGIKTPEIVAPQSAHAAFNKAASYFGMKIVRVPLT-KMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLDSLYSTDTVTQGSQMNGSPKPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V7Y2-1", "uniprot_id": "SGPL_DROME", "id": "Q9V7Y2-1", "name": "Sphingosine-1-phosphate lyase", "aln": "---------------------MRPFS-----GSDCLKPVTEGINRAFGAKEPWQ------VATITATTVLGGVWLWTVICQDENLYIR----GKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLTYSETLPEKGLSKEEILRLVDEH-LKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSAS-CGTMTTGGTESIVMAMKAYRDFAREYKGITRPNIVVPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLR-PFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTAR-YIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMK--DPGQPVVGKMALYGMAQSIPDRSVIGEVTRLFLHSMYYTPSQK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05567-1", "uniprot_id": "SGPL_YEAST", "id": "Q05567-1", "name": "Sphingosine-1-phosphate lyase", "aln": "MSGVSNKTVSINGWYGMPIHLLREEGDFAQFMILTINELKIAIHGYLRN-TPWYNMLKDYLFVIFCYKLISNFFYLLKVYGPVRLAVRTYEHSSRRLFRWLLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGGTESLLLACLSAKMYALHHRGITEPEIIAPVTAHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAH--VVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLGPGEDTATK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . :: ** : . : .: : * * ..: *: . * : :: :: *.*..: :: . . ** :*: ::. :.: *::*:.**:** .* .* . .* . :* **.*:**.: *:*:*:* :. :*:. . : ** *:*****:::* : : * . :**. *:*:.* :.**.*:*.. **.::: * :**: .:: *.:** :** *:*:**:* * : :. :. :*.:*.***:***.*:: ::.:*** :**.* ******.******:******:::* :.. : :*: * . * **:*.**:: ***.*.* ..***::: :* :**:*: :.*: :* : : .:* .: ::*.* ***::.*. ::*..**: : **::* ** * .:*:..* : :: *. :: :* . :: . :. * *:**:* : : :: **..:* . ", "identical_positions": 150, "similar_positions": 195, "identity": "25.04%" }, { "cls_id": "homologset.agr.SGD:S000002705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQV7-1", "uniprot_id": "CH25H_RAT", "id": "Q4QQV7-1", "name": "Cholesterol 25-hydroxylase", "aln": "-------MACHNVSELQDLGCSNQLLLQPLWDSIRT-GEASARSPFFPVIFSIFTYLGFCLPFVVLDVLCPWVPILRRYKIHPD----FSPSVRQLLPCLGLTLYQHLVFVFPVTLMHWA------------RSP-ALLPREAPELSQLLS--------HVLICLLLFDTEIFAWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELLSLTFFDV-LNVAMLQCHPLTILVFHVVNIWLSVEDHSGYDFPWSTHRLVPFGWYGGVAHHDLHHSQF--NCNFAP-YFTHWDKMLGT-----------LRCAPHSKRLCAGSESCLDSGEQCTVHLNQKKKQT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F5-1", "uniprot_id": "CH25H_MOUSE", "id": "Q9Z0F5-1", "name": "Cholesterol 25-hydroxylase", "aln": "-------MGCYNGSELQDLGCSSQLLLQPLWDTIRT-REAFTRSPIFPVTFSIITYVGFCLPFVVLDVLYPWVPILRRYKIHPD----FSPSVKQLLPCLGLTLYQHLVFVFPVTLLHWV------------RSP-ALLPQEAPELVQLLS--------HVLICLLLFDTEIFAWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSFWELLSLTFFDV-LNVAVLRCHPLTIFTFHVINIWLSVEDHSGYDFPWSTHRLVPFGWYGGVAHHDMHHSQF--NCNFAP-YFTHWDKMLGT-----------LRSAPLPESLCACGERCVNSRERCAVHLIQKKKQT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95992-1", "uniprot_id": "CH25H_HUMAN", "id": "O95992-1", "name": "Cholesterol 25-hydroxylase", "aln": "-------MSCHNCSDPQVLCSSGQLFLQPLWDHLRS-WEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVPALRRYKIHPD----FSPSAQQLLPCLGQTLYQHVMFVFPVTLLHWA------------RSP-ALLPHEAPELLLLLH--------HILFCLLLFDMEFFVWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDM-MNVTLLGCHPLTTLTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHF--NCNFAP-YFTHWDKILGT-----------LRTASVPAR--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PRC0-1", "uniprot_id": "CH25H_DANRE", "id": "Q5PRC0-1", "name": "Cholesterol 25-hydroxylase-like protein", "aln": "-----------------------MFGLQHIWDCILQ-YEAQLRSPFFPVLFSITVYLSFCLPFVLLDALSPKVELIRRYKIQQK----ASVSWTMMWSCLALSLYNHVVYIFPLSVLHWY------------WRP-VSYLAEAPGVLRVVW--------DLAACLLLFDFQYFVWHLLHHKVPWLYRTFHKVHHKYTSTFALATEYSGAWETLSLGFFAA-VNPMLLGVHPMTEMLFHMLNMWLSVEDHCGYDLPWATHRLMPFGLYGGAPHHDVHHQKF--KSNYAP-YFTHWDKLFGT-----------LHFE-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LX59-1", "uniprot_id": "C2512_DANRE", "id": "Q1LX59-1", "name": "Cholesterol 25-hydroxylase-like protein 1, member 2", "aln": "-------MTLAHIFQTIWDFGTKDSVLQPIWDYVRLNHSETLRSPLFPVVLTVSSYFVLVLPYLSCDILGRKWPAIYRYKIQPD----KLPTTAMLLHCSGVTLYNHILLVIPAAVAQWM------------WRPPIPLPEQAPTLLELVG--------GVTGNLLLFDLQYFIWHFLHHKIRWLYVTFHAIHHNYSAPFALATQCLGGWELVTVGFWTT-LNPVLLRCHLLTTWMFMVVHVYVSVEDHCGYDFPWSTSRLIPFGVYGGPSKHDVHHQKP--NTNFAP-HFSHWDKMFGT-----------HADFRFSKPRE------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q567X1-1", "uniprot_id": "C25L1_DANRE", "id": "Q567X1-1", "name": "Cholesterol 25-hydroxylase-like protein 1, member 1", "aln": "------MWNISEVVFQLPTSSASDRVLQPLWDYLLLRHYTLISSPFFPVLLAFSSYIIFSVPFAVLDVLGEKAP-LFKYKIQKD----RRPTVGMMLRTLWTAVYNHLVFVLPAVLITNV------------VMPMPPLPTVAPTVWEMFS--------GGLGALLVFDTQYFLWHMVHHKNPHLYRWVHAIHHDYISPFSWSTQHLSGVELMTVGFWSN-IDPILLKCHPLTVWTLTVYSIWMSVEDHIGYDLPFSPGHLVPFGLLGGAMAHDMHHQKP--SSNFAP-FFSHWDKIFGT-----------AITVKLTQKSEKEKQVA------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38992-1", "uniprot_id": "SUR2_YEAST", "id": "P38992-1", "name": "Sphingolipid C4-hydroxylase SUR2", "aln": "MNVTSNATAAGSFPLAFGLKTSFGFMHYAKAPAINLRPKESLLPEMSDGVLALVAPVVAYWALSGIFHVIDTFHLAEKYRIHPSEEVAKRNKASRMHVFLEVILQHIIQTIVGLIFMHFEPIYMTGFEENAMWKLRADLPRIIPDAAIYYGYMYGMSALKIFAGFLFVDTWQYFLHRLMHMNKTLYKWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTHLTHREQIILFTFATMKTVDDHCGYALPLDP---FQWLFPNNAVYHDIHHQQFGIKTNFAQPFFTFWDNLFQTNFKGFEEYQKKQRRVTIDKYKEFLQERELEKKEKLKNFKAMNAAENEVKKEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ::. . . : :*:*: . . : : : : :. . * :*..* : * : * ** .* :**. .:: .: . * . : : : : :*:** ** :* . . : .. **:**.: . *:* .*:.**::: * ", "identical_positions": 29, "similar_positions": 59, "identity": "8.24%" }, { "cls_id": "homologset.agr.SGD:S000002706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06647-1", "uniprot_id": "ATPO_RAT", "id": "Q06647-1", "name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial", "aln": "-MAAPATSVLSRQVRSFSTSVVRPFSKLVRPPVQVYGIEGRYATALYSAASKQKRLDQVEKELLRVGQLLK-DPKVSLAVLNPYIKRSIKVKSLKDITTKEK-FSPLTANLMNLLAENGRLGNTQGVISAFSTIMSVHRGEVPCTVTTAFPLDEAVLSELKTVLNS--FLSKGQILNLEVKTDPSIMGGMIVRIGEKYVDMSAKSKIQKLSKAMRDLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB20-1", "uniprot_id": "ATPO_MOUSE", "id": "Q9DB20-1", "name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial", "aln": "-MAAPAASGLSRQVRSFSTSVVRPFAKLVRPPVQVYGIEGRYATALYSAASKEKKLDQVEKELLRVGQLLK-DPKVSLAVLNPYIKRTVKVKSLNDITKREK-FSPLTANLMNLLAENGRLGNTQGIISAFSTIMSVHRGEVPCTVTTASPLDDAVLSELKTVLKS--FLSPNQILKLEIKTDPSIMGGMIVRIGEKYVDMSAKSKIQKLSKAMREML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48047-1", "uniprot_id": "ATPO_HUMAN", "id": "P48047-1", "name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial", "aln": "-MAAPAVSGLSRQVRCFSTSVVRPFAKLVRPPVQVYGIEGRYATALYSAASKQNKLEQVEKELLRVAQILK-EPKVAASVLNPYVKRSIKVKSLNDITAKER-FSPLTTNLINLLAENGRLSNTQGVVSAFSTMMSVHRGEVPCTVTSASPLEEATLSELKTVLKS--FLSQGQVLKLEAKTDPSILGGMIVRIGEKYVDMSVKTKIQKLGRAMREIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24439-1", "uniprot_id": "ATPO_DROME", "id": "Q24439-1", "name": "ATP synthase subunit O, mitochondrial", "aln": "-MAS--INKLALLSRTLSSAAAQ---ATVKPPVQVFGLEGRYATALYSAASKLSQLDQVEKDLTALQATIRSDKKLREYVTSPIINKKVMATALKEASEKLR-FAPATVNLLGLLADNGRLKKLDTVINAYKTIMAAHRGEVVCEVVTAKPLDASQSKQLEGALKS--FLKGNESLKITSRVDPSIIGGLIVSIGDKYVDMSIATKVKLYTDVIQTAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09457-1", "uniprot_id": "ATPO_YEAST", "id": "P09457-1", "name": "ATP synthase subunit 5, mitochondrial", "aln": "MFNRVFTRSFASSLRAAASKAAAP------PPVRLFGVEGTYATALYQAAAKNSSIDAAFQSLQKVESTVKKNPKLGHLLLNPALSLKDRNSVIDAIVETHKNLDGYVVNLLKVLSENNRLGCFEKIASDFGVLNDAHNGLLKGTVTSAEPLDPKSFKRIEKALSASKLVGQGKSLKLENVVKPEIKGGLIVELGDKTVDLSISTKIQKLNKVLEDSI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * :: .. ***:::*:** ******.**:* . :: . :.* : :: : *: : .* :. . . :. : : ..**: :*::*.** : : . : .: .*.* : *.:* **: ..:: .*.: :: .: *:: ..*.* **:** :*:* **:* :*:: .:. ", "identical_positions": 45, "similar_positions": 79, "identity": "20.64%" }, { "cls_id": "homologset.agr.SGD:S000002707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYW0-1", "uniprot_id": "AATF_RAT", "id": "Q9QYW0-1", "name": "Protein AATF", "aln": "-----MAELQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EEDDLPVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWDQTLPSSSDNEIPDEGGSEAGDSE--GLEELSED-----VEEDLEDNEIPDEGGSEDGDSEGL-EEEIS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVMA--FSGVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVKGTKPNAESEEISSEDDELVGEKKKQRK-APPKRKLEMEDYPSFMAKRSADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKR------------SAYRVLGKPEPVPEPVAETLPGEPESLPQVP--------ANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMNDEARTELYRSLFGQLNRLDADHGQ------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKX4-1", "uniprot_id": "AATF_MOUSE", "id": "Q9JKX4-1", "name": "Protein AATF", "aln": "-----MAAPQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EKDDLAVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWEQALPSSSDNEASDEGGSEDGDSEGLGLEEISED-----VDEDLEDNKISDEGGSEDGDSEGLGLEEFS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVAA--FSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNGAKPNTESEEISSEDDELVGEKKKQRK-APPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHIMMDKERLLRRTQTKR------------SAYRVLGKPEPVPEPVAETLPGEPETLPQGP--------ANAHLRDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMSDDARTELFRSLFGQLNPPDADRGK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY61-1", "uniprot_id": "AATF_HUMAN", "id": "Q9NY61-1", "name": "Protein AATF", "aln": "-----MAGPQPLALQLEQLLN-PRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMT--FSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKR------------SVYRVLGKPEPAAQPVPESLPGEPEILPQAP--------ANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TTMNDDARTELYRSLFGQLHPPDEGHGD------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM95-1", "uniprot_id": "AATF_DROME", "id": "Q9VM95-1", "name": "Protein Aatf", "aln": "MLRKSKKQPQTVAEKVSKLLAHPNESDSAEDSDFDVATGPRLVDFEE--EEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSE----EETAAGHSESGEESEEIESNLTDFKKKFEAG------------DFKYDDDEEEDDDSEEEDHSQESEGDDDDSEDDEAEDDAIKPSDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQLPAP-ETLTKLASESD-ELQSVLNEAQERSSKLLQQLLSLQSALHQQYSEMKKSVKRKQPTEDSG-------------------------PAVKKFGSVLQSNFQQMIGYRNEVLLKWDDRTKLLTPGAGVKRKSLQED-YDIIKKIGSALANREALVEKSQTPK------------NSQAEQQENTPVQR---------------------------------LKHIYDDSDFYHQQLRELIEYKASTS--SNMSEITKQFVELQKLRQKMKKKVDTRASKGRKLRYVVHNKLINFMAPNES-SDWTDASKSELYKSLFV-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06631-1", "uniprot_id": "BFR2_YEAST", "id": "Q06631-1", "name": "Protein BFR2", "aln": "-------MEKSLADQISDIAIKPVNKDFDIEDE----ENASLFQHNEKNGESDLSDYGNSNTEETKKAHYLEVEK---SKLRAEKGLELNDPKYTGVKGSRQALYEEVSENEDEEE---------------EEEEEEEKEEDALSFRTDSEDEEVEIDEEE------------------SDADGGET---------EEAQQKRHALSKLIQQETKQAINKLSQSVQRDASKGYSILQQTKLFDNIIDLRIKLQKAVIAANKLPLTTESWEEAKMDDSEETKRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVAKHKLSKKR--------------------------SLKELYQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSRLMKRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVDDNENSDDGLDIPKNYDPRRKDNNAIDITENPYVFDDEDFYRVLLNDLIDKKISNAHNSESAAITITSTNARSN-NKLKKNIDTKASKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQRVNFNENEDEEQHARIENDEELEAVKNDDIQIFG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* ::..: * : : : . :.: : : : . .: : .. .* :.* . :. . * : :: . .: : . . . ... . . .* : . * ::. : :: : . . : .** :: :* :::.::: **: ** :*:** . : ... * *:: .: . *:. *:.:: : : : . ::. . . :: **. .* ** :.. : . :: :: : : . *:.::: : *. . ::**.***: *.:**: * *. .: : :. .*::*::* :*******.: * . : .: ** .* *:: .*: ", "identical_positions": 54, "similar_positions": 152, "identity": "8.75%" }, { "cls_id": "homologset.agr.SGD:S000002709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYV2-1", "uniprot_id": "A0A0G2JYV2_RAT", "id": "A0A0G2JYV2-1", "name": "Cleavage and polyadenylation specificity factor subunit 1", "aln": "MYAVYKQAHPPTGLEFAMYCNFFNNSERNLVVAGTSQLYVYRLNRDAEALTKN--DGSTEGKAHREKLELVASFSFFGNVMSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHE------------GLMGEGQRSS-----------------FLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNITQKVHP------VIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQS-VPPYGVALNSLTTGTTAFP-LRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEK-------------------LQEPPASSVREAADKE-EPPSKKKRVDP-TVGWTG-GKT--QDEVDEIEVYGSEAQSG-TQLATYSFEVCDSMLNIGPCANAAVGEPAFLSEEFQNS-------PEPDLEIVVCSGYGKNGALSVLQKSIRPQVVTTFELPGCYDMWTVIAPVRKEEEETPKAES-TEQEPS-APKAEEDGRRHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVIA-LCLYRDVSGMFTTESRLG-GARDELGGRSGSEAEGLGSETSPTVDDEEEMLYGDSSSLFSPSKEEARR----SNQPPADRDP-APFRADPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVLVD-------SSFGQPTTQGEVRKEEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGCSTEEGSGVRGR-VARFRYFEDIYGYSGVFICGPSPHWLLVTGRGALRLHPMGIDGPIDSFAPFHNVNCPRGFLYFNRQGELRISVLPAY-LSYDAPWPVRKIPLR------CTAHYVAYHVESKVYAVATSTNTPCTRIPRMTGEEKEFEAIERDDRYIHPQQEAFSIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLR-ASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGAAEGPSKKSVMWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRILQNAVRNVLDGELLNRYLYLSTMERSELAKKIG----TTPDIARVVDICALCPCRMETARPWQSFWLRELHLQVLIDLLSLSLGGKAQADHNTQHEGGEPHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPU4-1", "uniprot_id": "CPSF1_MOUSE", "id": "Q9EPU4-1", "name": "Cleavage and polyadenylation specificity factor subunit 1", "aln": "MYAVYKQAHPPTGLEFTMYCNFFNNSERNLVVAGTSQLYVYRLNRDAEALTKN--DGSTEGKAHREKLELVASFSFFGNVMSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHE------------GLMGEGQRSS-----------------FLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNITQKVHP------VIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQS-VPPYGVALNSLTTGTTAFP-LRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEK-------------------LQEPPASSVREAADKE-EPPSKKKRVEP-AVGWTG-GKTVPQDEVDEIEVYGSEAQSG-TQLATYSFEVCDSMLNIGPCANAAVGEPAFLSEEFQNS-------PEPDLEIVVCSGYGKNGALSVLQKSIRPQVVTTFELPGCYDMWTVIAPVRKEEEETPKAES-TEQEPS-APKAEEDGRRHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVIA-LCLYRDVSGMFTTESRLG-GARDELGGRSGSEAEGLGSETSPTVDDEEEMLYGDSSALFSPSKEEARR----SSQPPADRDP-APFKADPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVLVD-------SSFGQPTTQGEVRKEEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGCSTEEGSGGRGR-VARFRYFEDIYGYSGVFICGPSPHWLLVTGRGALRLHPMGIDGPIDSFAPFHNVNCPRGFLYFNRQGELRISVLPAY-LSYDAPWPVRKIPLR------CTAHYVAYHVESKVYAVATSTNTPCTRIPRMTGEEKEFEAIERDDRYIHPQQEAFSIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLR-ASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGAAEGPSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRILQNAVRNVLDGELLNRYLYLSTMERSELAKKIG----TTPDII---------------------------------------LDDLLETDRVTAHF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q10570-1", "uniprot_id": "CPSF1_HUMAN", "id": "Q10570-1", "name": "Cleavage and polyadenylation specificity factor subunit 1", "aln": "MYAVYKQAHPPTGLEFSMYCNFFNNSERNLVVAGTSQLYVYRLNRDAEALTKN--DRSTEGKAHREKLELAASFSFFGNVMSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHE------------GLVGEGQRSS-----------------FLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNITQKVHP------VIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQS-VPPYGVALNSLTTGTTAFP-LRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEK-------------------LQEPPASAVREAADKE-EPPSKKKRVDA-TAGWSAAGKSVPQDEVDEIEVYGSEAQSG-TQLATYSFEVCDSILNIGPCANAAVGEPAFLSEEFQNS-------PEPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFELPGCYDMWTVIAPVRKEEEDNPKGEG-TEQEPSTTPEADDDGRRHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVIT-LCLYRDLSGMFTTESRLG-GARDELGGRSGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKEEARR----SSQPPADRDP-APFRAEPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVLVD-------SSFGQPTTQGEARREEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGGGAEEGAGARGR-VARFRYFEDIYGYSGVFICGPSPHWLLVTGRGALRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNRQGELRISVLPAY-LSYDAPWPVRKIPLR------CTAHYVAYHVESKVYAVATSTNTPCARIPRMTGEEKEFETIERDERYIHPQQEAFSIQLISPVSWEAIPNARIELQEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLR-ASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGATEGLSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRTLQNAVRNVLDGELLNRYLYLSTMERSELAKKIG----TTPDII---------------------------------------LDDLLETDRVTAHF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NHR0-1", "uniprot_id": "A0A8M1NHR0_DANRE", "id": "A0A8M1NHR0-1", "name": "Cleavage and polyadenylation specificity factor subunit 1", "aln": "MYAVYRQAHPPTAVEFAVYCNFISSQEKNLVVAGTSQLYVYRIIYDVESTSKS--EKSSDGKSRKEKLEQVASFSLFGNVMSMASVQLVGTNRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHIPMVRVDPENRCAVMLVYGTCLVVLPFRKDTLADEQE------------GIVGEGQKSS-----------------FLPSYIIDVRELDEKLLNIIDMKFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNIMQKVHP------VIWSLSNLPFDCNQVMAVPKPIGGVVVFAVNSLLYLNQS-VPPFGVSLNSLTNGTTAFP-LRPQEEVKITLDCSQASFITSDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTCMMTMEPGYLFLGSRLGNSLLLRYTEK-------------------LQETPMEEGKENEEKEKQPPNKKKRVDS-NWAGCP-GKGNLPDELDEIEVYGSEAQSG-TQLATYSFEVCDSILNIGPCASASMGEPAFLSEEFQTN-------PEPDLEVVVCSGYGKNGALSVLQKSIRPQVVTTFELPGCHDMWTVIYCEEKPEKPSAEGDGESPEEEKREPTIEDDKKKHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVYAGNIGDNKYIIQVSPMGIRLLEGVNQLHFIPVDLGSPIVHCSVADPYVVIMTAEGVVTMFVLKNDSYMGKSHRLALQKPQIHTQSRVIT-LCAYRDVSGMFTTENKVSFLAKEEIAIRTNSETETIIQDISNTVDDEEEMLYGESNPLTSPNKEESSRGSAAASSAHTGKES-GSGRQEPSHWCLLVRENGVMEIYQLPDWRLVFLVKNFPVGQRVLVD-------SSASQSATQGELKKEEVTRQGDIPLVKEVALVSLGYNHSRPYLLAHVEQELLIYEAFPYDQQQAQSNLKVRFKKMPHNINYREKKVKVRKDKKPEGQGEDTLGVKGR-VARFRYFQDISGYSGVFICGPSPHWMLVTSRGAMRLHPMTIDGAIESFSPFHNINCPKGFLYFNKQGELRISVLPTY-LSYDAPWPVRKIPLR------CTVHYVSYHVESKVYAVCTSVKEPCTRIPRMTGEEKEFETIERDERYIHPQQDKFSIQLISPVSWEAIPNTRVDLEEWEHVTCMKTVALKSQETVSGLKGYVALGTCLMQGEEVTCRGRILILDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCSGFLVSAIGQKIFLWSLK-DNDLTGMAFIDTQLYIHQMYSIKNFILAADVMKSISLLRYQPESKTLSLVSRDAKPLEVYSIEFMVDNNQLGFLVSDRDKNLMVYMYLPEAKESFGGMRLLRRADFNVGSHVNAFWRMPCRGTLDTANKKALTWDNKHITWFATLDGGVGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPKAFRMLHCDRRTLQNAVKNILDGELLNKYLYLSTMERSELAKKIG----TTPDII---------------------------------------LDDLLEIERVTAHF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V726-1", "uniprot_id": "CPSF1_DROME", "id": "Q9V726-1", "name": "Cleavage and polyadenylation specificity factor subunit 1", "aln": "MFSMCKQTHSATAVEFSIACRFFNNLDENLVVAGANVLKVYRIAPNVEASQRQKLNPSEMRLAPKMRLECLATYTLYGNVMSLQCVSLAGAMRDALLISFKDAKLSVLQHDPDTFALKTLSLHYFEEDDIRGGWTGRYFVPTVRVDPDSRCAVMLVYGKRLVVLPFRKDNSLDEIELADVKP---IKKAPTAMVSRTP-----------------IMASYLIALRDLDEKIDNVLDIQFLHGYYEPTLLILYEPVRTCPGRIKVRSDTCVLVAISLNIQQRVHP------IIWTVNSLPFDCLQVYPIQKPIGGCLVMTVNAVIYLNQS-VPPYGVSLNSSADNSTAFP-LKPQDGVRISLDCANFAFIDVDKLVISLRTGDLYVLTLCVDSMRTVRNFHFHKAAASVLTSCICVLHSEYIFLGSRLGNSLLLHFTEEDQS------------TVITLDEVEQQSEQQQRNLQDEDQNLEEIFDVDQLEMAPTQAKSRRIEDEELEVYGSGAKASVLQLRKFIFEVCDSLMNVAPINYMCAGERVEFEEDGVTLRPHAESLQDLKIELVAATGHSKNGALSVFVNCINPQIITSFELDGCLDVWTVFDDATKKSSRN---------------------DQHDFMLLSQRNSTLVLQTGQEINEIENTGFTVNQPTIFVGNLGQQRFIVQVTTRHVRLLQGTRLIQNVPIDVGSPVVQVSIADPYVCLRVLNGQVITLALR-ETRG--TPRLAINKHTISSSPAVVA-ISAYKDLSGLFTVKGDDINLTGSSNSAFGHSFGGYMKAEPNMKVEDEEDLLYGDAGSAFKMNSMADLAKQ--SKQKNSDWWRRLLVQAKPSYWLVVARQSGTLEIYSMPDMKLVYLVNDVGNGSMVLTDAMEFVPISLTTQENSKAGIVQACMPQHANSPLPLELSVIGLGLNGERPLLLVRTRVELLIYQVFRYP----KGHLKIRFRKMDQLNLLDQQPTHIDLDENDEQEEIESYQMQPKYVQKLRPFANVGGLSGVMVCGVNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVNIPNGFLYFDTTYELKISVLPSY-LSYDSVWPVRKVPLR------CTPRQLVYHRENRVYCLITQTEEPMTKYYRFNGEDKELSEESRGERFIYPIGSQFEMVLISPETWEIVPDASITFEPWEHVTAFKIVKLSYEGTRSGLKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMTKFKIKEIFKKEQKGPVSAISDVLGFLVTGLGQKIYIWQLR-DGDLIGVAFIDTNIYVHQIITVKSLIFIADVYKSISLLRFQEEYRTLSLASRDFNPLEVYGIEFMVDNSNLGFLVTDAERNIIVYMYQPEARESLGGQKLLRKADYHLGQVVNTMFRVQCHQKG-LHQRQPFLYENKHFVVYGTLDGALGYCLPLPEKVYRRFLMLQNVLLSYQEHLCGLNPKEYRTLKSSKKQGINPSRCIIDGDLIWSYRLMANSERNEVAKKIG----TRTEEI---------------------------------------LGDLLEIERLASVF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06632-1", "uniprot_id": "CFT1_YEAST", "id": "Q06632-1", "name": "Protein CFT1", "aln": "-MNVYDDVLDATVVSHSLATHFTTSDYEELLVVRTNILSVYRPTRDGKLYLTD-------------------EFKFHGLITDIGLIPQKDSPLSCLLLCTGVAKISILKFNTLTNSIDTLSLHYYEGKFKGKSLVELAKISTLRMDPGSSCALLFNN-DIIAFLPFHVNKNDDDEEEEDEDENIDDSELIHSMNQKSQGTNTFNKRKRTKLGDKFTAPSVVLVASELYEGAKNIIDIQFLKNFTKPTIALLYQPKLVWAGNTTISKLPTQYVILTLNIQPAESATKIESTTIAFVKELPWDLHTIVPVSN---GAIIVGTNELAFLDNTGVLQSTVLLNSFADKELQKTKIINNSSLEIMFREKNTTSIWIPSSKSKNGGSNNDETLLLMDLKSNIYYIQMEAEGRLLIKFDIFKLPIVNDLLKENSNPKCITRLNATNSNKNMDLFIGFGSGNALVLRLNNLKSTIETREAHNPSSGTNSLMDINDDDDEE-MDDLYADEAPENGLTTNDSKGTVETVQPFDIELLSSLRNVGPITSLTVGKVSSIDDVVKGLP----NPNKNEYSLVATSGNGSGSHLTVIQTSVQPEIELALKFISITQIWNLKIKGR---------------------------DRYLITTDSTKSRSDIYESDNNFKLHKGGRLRRDATTVYISMFGEEKRIIQVTTNHLYLYD-THFRRLTTIKFDYEVIHVSVMDPYILVTVSRGDIKIFELEEKNKR---KLLKVDLPEILNEMVITSGLILKSNMCNEFLIG---------------------------LSKSQEEQLLFT------------------------------FVTADNQIIFFTKDHNDRIFQLNGVDQLNESLYISTYQLGDEIVPD------------------------------PSIKQVMINKLGHDNKEEYLTILT-----------------FGGEIYQYRKLPQRRSRFYRNVTRNDLAITGAPDNAYAKGVSSIERIMHYFPDYNGYSVIFVTGSVPYILIKEDDSTPKIFKFG-NIPLVSVTPWS----ERSVMCVDDIKNARVYTLTTDNMYYGNKLPLKQIKISNVLDDYKTLQKLVYHERAQLFLVSYCKRVPYEALG-----EDGEKVIGYDENVPHAEGFQSGILLINPKSWKVID--KIDFPKNSVVNEMRSSMIQINSKTKRKREYIIAGVANATTEDTPPTGAFHIYDVIEVVPEPGKPDTNYKLKEIFQEEVSGTVSTVCEVSGRFMISQSQKVLVRDIQEDNSVIPVAFLDIPVFVTDSKSFGNLLIIGDAMQGFQFIGFDAEPYRMISLGRSMSKFQTMSLEFLVNGGDMYFAATDADRNVHVLKYAPDEPNSLSGQRLVHCSSFTLHSTNSCMMLLPRNEEFGSPQVPSFQNVG------GQVDGSVFKIVPLSEEKYRRLYVIQQQIIDRELQLGGLNPRMERLAN-DFYQMGHSMRPMLDFNVIRRFCGLAIDRRKSIAQKAGRHAHFEA------------------------------------------WRDIINIEFSMRSLCQGK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .* :..:: .* .. .:*:*. :. * *** : : . :.:.* : .: : .: ..**:. **:*:::.:. * :.******:* . . . :*:** . ** :: :..***: :. :: * . .:: .* :: * * *::*::**:.: :**: :*::* . .*. : . . * ::*** . * :..**:* .: : * ::. .* : :*::: * * *** : . : :. :.* : : : * . . .: * * .: :::. . ::. : : :* .. . . : : . * . : : . . :. .: * * : . ::. : : :*: .*: *:.* *: :.: . . .:*. :* .... *:*: ..:.*:: :::: . ::*.: :: : * .. : : ::.::: . : : .*:: . :*::: *:**:. : * : .. : .:... ::: :: ***: : .* : : *. .. * :. : . : : : ::.. * . .:**::*: . : ::. ::: : : . :. *. :: * * :: : ** .. * . . :::*: : : :: * : * * ::: * * :: . ::. : : : *.:.: ...: .: : :: .*.: : *. *:::: : * : : ** . ::: : . * :. . .:. :. : **.* :*: : : : . *. :: : : . . : *: *. *: . * : * *:********:* *: *:* ::::* .*.*:::.. * :: . .**: : .:: ..: :**:* ::: : :. .::: .*. :.:.:: :: * : .*. . ::. .::*:*:. :: * .:* ::*: * * *: :*:.* :*:: :.: : . : . . .. . . :**.: :*: *: ***: ::*: : : ****: * : . :. : ::* ::: : :: .*..:*:* * . . : : ", "identical_positions": 179, "similar_positions": 486, "identity": "11.3%" }, { "cls_id": "homologset.agr.SGD:S000002710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZK79-1", "uniprot_id": "A0A8I5ZK79_RAT", "id": "A0A8I5ZK79-1", "name": "", "aln": "----MKDTDIKRLLYTNLLCIFSVFLSIFIPSFFLDNFSI---LETHLVWLGTCSAFVTGANLLLYLVVKPNVSSKR---SSLSHKVARVVRCWLYFLASCFFLHIIFVLYGAPLMELVL-ETFLFAVVLSTFTTVPCLCLLGPNLKAWLR-----VFSRNGVTSVWENSLQITTVSS-----FIGAWLGAFPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09101-1", "uniprot_id": "PIGF_MOUSE", "id": "O09101-1", "name": "GPI ethanolamine phosphate transferase, stabilizing subunit", "aln": "----MKDTDIKRLLYTNLLCVFSIFLSIFIPSFFVDNFSV---LEAHLTWLCICSASVTTVNLLSYLVVKPNVSSKR---SSLSHKVTRALKCCVCFLMSCFLLHIIFVLYGAPLIELVL-ETFLFAVVLSTFTTVPCLCLLGPNLKAWLR-----VFSRNGVTSIWENSLQITTISS-----FTGAWLGAFPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07326-1", "uniprot_id": "PIGF_HUMAN", "id": "Q07326-1", "name": "GPI ethanolamine phosphate transferase, stabilizing subunit", "aln": "----MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSI---LETHLTWLCICSGFVTAVNLVLYLVVKPNTSSKR---SSLSHKVTGFLKCCIYFLMSCFSFHVIFVLYGAPLIELAL-ETFLFAVILSTFTTVPCLCLLGPNLKAWLR-----VFSRNGVTSIWENSLQITTISS-----FVGAWLGALPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06636-1", "uniprot_id": "GPI11_YEAST", "id": "Q06636-1", "name": "Glycosylphosphatidylinositol anchor biosynthesis protein 11", "aln": "--MPAKKRTRKTVKKTVSFSDDTTLTTHQNREKKNVDHDR---PPVYVRKTPLMTFPYHLVALLYYYVFVSSNFNTV---KLLSFLIPTQVAYLVLQFNKCTVYGNKIIKINYSLTIICLGVTFLLSFPTMLLTILFGAPLMDLLWETWLLSLHFAFLAYPAVYSVFNCDFKVGLWKKYFIFIVVGGWISCVVIPLDWDRDWQNWPIPIVVGGYLGALVGYTIGAYI---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VW21-1", "uniprot_id": "Q9VW21_DROME", "id": "Q9VW21-1", "name": "", "aln": "MVSRFDQQKTKHQLFHVSLSLATILICMAYMQYRRNWAHLGSFWDSLVVPIVFLGELLKVVLARFYGKVEDGVLTAKQRQKKNSYFTPRELLGGFTLQFLCTLLYAFICIILGAPVLGNYEQTFVLALLMTLLTVSPTVFLLGGGGALQVCFCEKPDFVTKCEDTALN-LFKYNALGG-----ILGAWAGSVVAPLDWGRDWQAYPIPNVIGALLGSALGNIYACTHVLYATARVYMTKKRT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * :. : : . : . * . . . . *. . : . * : . **:::. :* *:. : : : : :: . *.* ... **** * ** :**. .:*. :* * . ", "identical_positions": 22, "similar_positions": 44, "identity": "9.09%" }, { "cls_id": "homologset.agr.SGD:S000002712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30412-1", "uniprot_id": "PPIC_MOUSE", "id": "P30412-1", "name": "Peptidyl-prolyl cis-trans isomerase C", "aln": "----MSPGPRLLLPAVLCLG--LGALVSSSGSSGVRKRGPSVTDKVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATG-EKGYGYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDEN--FKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHDRPLTDCTIVNSGKID-----------------------VKTPFVVEVPDW----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FHM1-1", "uniprot_id": "F7FHM1_RAT", "id": "F7FHM1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "----MSRGPRLLLPAVLFLG--LGGLVSSSGSSGVRKRGPLVTDKVFFDVRIGDKDVGRIVIGLFGKVVPRTVENFVTLATG-EKGYGYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDEN--FKLKHYGIGWVSMANAGPDTNGSQFFITLTKPAWLDGKHVVFGKVLDGMTVVHSIELQATDDHDRPLTDCTIVNSGKID-----------------------VKTPFVVEVPDW----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45877-1", "uniprot_id": "PPIC_HUMAN", "id": "P45877-1", "name": "Peptidyl-prolyl cis-trans isomerase C", "aln": "----MGPGPRLLLPLVLCVG--LGALVFSSGAEGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATG-EKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPDEN--FKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVVHSIELQATDGHDRPLTNCSIINSGKID-----------------------VKTPFVVEIADW----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24369-1", "uniprot_id": "PPIB_MOUSE", "id": "P24369-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATG-EKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDEN--FKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIE-----------------------VEKPFAIAKE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24368-1", "uniprot_id": "PPIB_RAT", "id": "P24368-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATG-EKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDEN--FKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVIIVDCGKIE-----------------------VEKPFAIAKE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23284-1", "uniprot_id": "PPIB_HUMAN", "id": "P23284-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATG-EKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDEN--FKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIE-----------------------VEKPFAIAKE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W227-1", "uniprot_id": "Q9W227_DROME", "id": "Q9W227-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "--------MKLFLSVFVVA------LVAGVVVADDSK-GPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALK-PQGEGYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDEN--FKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTLP-----------------------VSEAFSVAKADATD--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35176-1", "uniprot_id": "CYPD_YEAST", "id": "P35176-1", "name": "Peptidyl-prolyl cis-trans isomerase D", "aln": "--------MKLQFFSFITLF--ACLFTTAIFAKEDTAEDPEITHKVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLTISRDPKMGYLNSIFHRVIPNFMIQGGDFTHRSGIGGKSIFGNTFKDEN--FDVKHDKPGRLSMANRGKNTNGSQFFITTVPCPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVESGELETVPLDNKDAAK------------LQEEIKAEASEAAHDEL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15425-1", "uniprot_id": "CYPR_DROME", "id": "P15425-1", "name": "Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme", "aln": "--------MKSLLNRIILCS---------AFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :* ::::*. . : **: :**:* .*:** ** : .* .* ***:: *::****:. .* *. **:*: * **: : ::* * :.*** * :***.**::* ****:*.***:::.** .: :* ** : *: * :.* : : : ", "identical_positions": 58, "similar_positions": 56, "identity": "22.83%" }, { "cls_id": "homologset.agr.SGD:S000002713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIX3-1", "uniprot_id": "FHIT_RAT", "id": "Q9JIX3-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLR-PVERFRDLRPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEEEMAAEAEVLRAYFQA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89106-1", "uniprot_id": "FHIT_MOUSE", "id": "O89106-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEKEMAAEAEALRVYFQA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49789-1", "uniprot_id": "FHIT_HUMAN", "id": "P49789-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKE---------------------------------------------DFPASWRSEEEMAAEAAALRVYFQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49775-1", "uniprot_id": "HNT2_YEAST", "id": "P49775-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "MNKPIYFSKFLVT-EQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINN-VGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *.:.*:. . ** *:: ::**** **:******: *** .* .: ** * * *:. * : .:: :::. *:..::********:* *:*.*::** : .* **::*:: * : * *: ** ** *:. :: ", "identical_positions": 54, "similar_positions": 49, "identity": "25.96%" }, { "cls_id": "homologset.agr.SGD:S000002716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ39-1", "uniprot_id": "MED21_MOUSE", "id": "Q9CQ39-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFSNIQ-TAINKDQPANPTEEYAQLFAAL---IARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSVTHS-HSLPDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA11-1", "uniprot_id": "D4AA11_RAT", "id": "D4AA11-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFSNIQ-TAINKDQPANPTEEYAQLFAAL---IARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSVTHS-QSLPDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13503-1", "uniprot_id": "MED21_HUMAN", "id": "Q13503-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFNNIQ-TAINKDQPANPTEEYAQLFAAL---IARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSGTHS-QSLPDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTI5-1", "uniprot_id": "MED21_DANRE", "id": "Q7ZTI5-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MADRLTQLQDAVNSLADQFCNAIGVLQQCAPPASFSNIQ-TAINKDQPSNPTEEYAQLFAAL---IARTAKDVDVLIDSLPSEESTAALQAASLRQLEEENQEAAARLEEVVYRGDALLEKIQTALADIAQSQLRTRSGAPSQQTPPES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5P1-1", "uniprot_id": "MED21_DROME", "id": "Q9W5P1-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MADRLTQLQDTVNQQAEHFCNAIGVIQQTSLPSKFVNFERIGPQTPIPCPPQEDYAQLFAQL---IARCAKDIDTLIESLPNEDSSIELQNSSLKRLEIENQGTARDLEEVVQKGELLLEKMQYSLECIAQAQLDMQITLKH--DLQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47822-1", "uniprot_id": "MED21_YEAST", "id": "P47822-1", "name": "Mediator of RNA polymerase II transcription subunit 21", "aln": "MTDRLTQLQICLDQMTEQFCATLNYIDKNHGFERLTVNEPQMSDKHATVVPPEEFSNTIDELSTDIILKTRQINKLIDSLPGVDVSAEEQLRKIDMLQKKLVEVEDEKIEAIKKKEKLLRHVDSLIEDFVDGIANSKKST---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******* ::. :::** ::. ::: : : :. . * *:::: : * * ::::: **:***. : : * .: *: : . :.: : : **.::: : :.:. : ", "identical_positions": 23, "similar_positions": 52, "identity": "15.44%" }, { "cls_id": "homologset.agr.SGD:S000002719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWQ0-1", "uniprot_id": "A0A0G2JWQ0_RAT", "id": "A0A0G2JWQ0-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATESS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTALE----DKPLDEGYG---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVTHIEEMLQTAYNKLHSWQSRRLMKKT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBA9-1", "uniprot_id": "TF2H1_MOUSE", "id": "Q9DBA9-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTSLE----DKPLDEGYS---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32780-1", "uniprot_id": "TF2H1_HUMAN", "id": "P32780-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPLLDLTALE----DKPLDEGYG---ISSVPSASNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQEAQNEQTSEPSNMDG------------------------NSGDADCFQPAVKRAKLQESIEYEDLG----------KNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AINQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q960E8-1", "uniprot_id": "TF2H1_DROME", "id": "Q960E8-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MTTSSEDVLLQMGEVRYKKG-------------DGTLYVMNERVAWMAEHRDTVTVSHRYADIKTQKISPEGKPKVQLQVVLHDGNTSTFHFVNRQGQAAMLADRDKVKELLQQLLPNFKRKVDKDLEDKNRILVENPNLLQLYKDLVITKVLTSDEFWATHAKDHALKKM---GRSQEIGVSGAFLADIKPQTDGCNGLKYNLTSDVIHCIFKTYPAVKRKHFENVPAKMSEAEFWTKFFQSHYFHRDR----LTAGTKDIFTECGKIDDQALKAAVQQGAGDPLLDLKKFE----DVPLEEGFGS--VAGDRNVVNSGNIVHQN---MIKRFNQHSIMVLKTCANVTSAPSTMTNGTNNANGPVSQSAYTNGMNGKGQATATATKSSSDQVDKDEPQSKKQRLMEKIHYVDLGDPILEGDDSANGEKAKSKHFELSKVERYLNG--PVQNSMYDNHNDPMSLEEVQYKLVRNSESWLNRNVQRTFICSKAAVNALGELSPGGSMMRGFQEQ---SAGQLVPNDFQRELRHLYLSLSELLKHFWSCFPPTSEELETKLQRMHETLQRFKMAKLVPFENRAMHELSPLRSSLTQHLNQLLRTANSKFATWKERKLRNTR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32776-1", "uniprot_id": "TFB1_YEAST", "id": "P32776-1", "name": "General transcription and DNA repair factor IIH subunit TFB1", "aln": "MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFAL---STSQKVGP-YNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDE------------------------DNDERNELKIDDLNESYKTNYAIIHLKRN---AHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.: :* : :* .* : :: : :* . : * * . : . . : . * . ..: . . ::. : : : : : . *.* .:*: :: :* : *:::::: *:. :...***:.: . .*.:* .*: ::* :.. * :. **: : * **..** ** : :.** ::.* ***::**.*: *:: * : . *:: : :: :. . .*: .: :: * *: .* *. . . ::*:..: *.* . . . .. : ...: : : . . .* ..:..*: .:.: : . :*. : . . .: . . .: . . . *. *::: . : . :* *: . : *: : *:*:**: * .: :: . *: *:: : : .. . ::: :*.: .:.. . ", "identical_positions": 67, "similar_positions": 197, "identity": "9.96%" }, { "cls_id": "homologset.agr.SGD:S000002720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YU8-1", "uniprot_id": "SSF1_MOUSE", "id": "Q91YU8-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRNRAQAQLRNLESYAAQPHSFVFTRGRAGRNVRQLSLDVRRVMEPLTATRLQVRKKNSLKDCVAVAGPLGVTHFLILTKTDNS--VYLKLMRLPGGPTLTFQISKYTLIRDVVSSLRR-HRMHEQQFNHPPLLVLNSFGPQGM---------HIKLMATMFQNLFPSINVHTVNLNTIKRCLLINYNPDSQELDFRHYSVKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GVGLSDSEVEPDGEHNTTELPQAVAGR--------------------------------------GNMQAQQSAVRLTEIGPRMTLQLIKIQEGVGNGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQNQQAENLQRKQELREAHKKKSLAGIKRARAR-ADGDSDAEDPGAPPEAVGAGQPEDEEDDAEYFRQAVGEEPDEDLFPTAAKRRRQGGPLG-----KKQRGKEQRPGNKGRGQGGN--WQALKLQGRSQRGKAKPRPRATHQDS---RPASRRRN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ55-1", "uniprot_id": "SSF1_HUMAN", "id": "Q9NQ55-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTASRLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETN--VYFKLMRLPGGPTLTFQVKKYSLVRDVVSSLRR-HRMHEQQFAHPPLLVLNSFGPHGM---------HVKLMATMFQNLFPSINVHKVNLNTIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GAGLSESEAEPDGDHNITELPQAVAGR--------------------------------------GNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGR-----KRKRWEMDR----GRGRLCD--QKFPKTKDKSQGAQARRGPRGASRDGG--RGRGRGRPGKRVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDE5-1", "uniprot_id": "PPAN_DROME", "id": "Q9VDE5-1", "name": "Protein Peter pan", "aln": "MGGK-KKVHPKTRTAAFKASEPSEIVEAPHSFVIHRGLACPYITDLTLDFRRIMEPFTASNLREKRMNRIKDFVSLSSFFHVSHMGIFNKASTQ--LSFKVVRLPRGPSLTFKVHQFTLARDVISLSKK-QMIDNDHFKHAPLVIMNNFSGDGK---------HLKLMATTFQNMFPSINLATVNIGTIRRCVLFSYNPDTKLVEMRHYSVQVVPVGLKRAVQKIVKGT------VPNLGKCNEVVDFVTK---DGYASESEAE-DDEQSHVVLAQTLKSK--------------------------------------GNLEDKKSSIKLHEIGPRLTMQLIKIEEGLLTGEVLYHDHVVKTEDEKETLRKLVEKKRKQKEQRKKEQAENRARNLKLKKDEK----WAAKRAAEGRTDSDP--------------------EDDAEYYKEEVGEEPDEELFKMEAKSSRKRPSLGGGMKYKNKRAKLDTKDKNDKSERTDKYDRKDKFDRKDKKDKFDPKNRRAKFDPKNKRAKFDHRKSRKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12153-1", "uniprot_id": "SSF2_YEAST", "id": "Q12153-1", "name": "Ribosome biogenesis protein SSF2", "aln": "---MAKRRQKKRTHAQITPEQERDIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAVKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSDEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRIFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQTSLSQKTPVKMTDNEEREKGIEEEDVEMEEPKPSENSQPTPRKKAIKLTELGPRLTLKLVKIEDGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRRKEQEENIAKKKAVKDAKKQRKLERRKARAEEQGEGQGKD----------GAMSDDGSSSSEDEHYSDVPEDLDSDLFSEVE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * : * . : : :* *.*::*:* ** .*: :: * :** * :.. : *:*: ::.::.. : :*: * * **::**:: .::* **: . :: : :.::.. :.**:::*.*. *::.: ***:**.:* ..:.:*:* .::. : :: :.:*** :.: * .* :::: : . .**: : ::: .:: . *:** * * . :. : .: ::.:::* *:***:*::*:*:::*: *:*:.*..* *:.:* ::: * : * **: :* :* :: :. .: * : : ... : . . * * ..:** ", "identical_positions": 78, "similar_positions": 154, "identity": "14.31%" }, { "cls_id": "homologset.agr.SGD:S000002721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76902-1", "uniprot_id": "PKHF1_DROME", "id": "O76902-1", "name": "Pleckstrin homology domain-containing family F member 1 homolog", "aln": "--MVDRLVNSEANTRRIASVENCFGSSGVPLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVYGNIVIGKKKYNKQHIMPLEEVSLESIADNQTYRNGWYIRTTTKSFVVFAATSTEKQEWMAHINKCVEDLLRKSGKKPVENHAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQSTKALRVCDACYERLKHVPSSLGSGEDSAAATGAASGNKLNTTAGDSSNDEDSDEETASPGGESHDEPRFYGDNSVLSAVEDSSTITSPSSATTGSLEAPQVTPSVQSSPAAVATTGSHC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06651-1", "uniprot_id": "PIB1_YEAST", "id": "Q06651-1", "name": "E3 ubiquitin-protein ligase PIB1", "aln": "MVIKEDCINNLARWQADEEAHSCFQCKTN--------------FSFLVR-----RHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSD--VESPPYRTCNECYDNLLHLNLLVSSTN--RDVRLSQTSVPPNALALSAPDSNTDEDAEILEDSVDQSGTACRSEESSQNEEDHFCP-----ICN-SDLTQFPDEEETRKHVEDCIQRAENAQQHTNTSDAADDSVKESPAFQNRMLVYKISPNTTDNAIKECPICFENMEPGEK--VGRLECLCVFHYKCIKNWFHKRAQMTAAQKGNGHAFVKRNFCPFHDAVF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*. *. : ....** .. :: : * *:. . :. .. . . :***::: .*:: . : .:. .**. . : ::.:::. :: .. : * *. .. :. * : *: . *:. : : :. *.* :* .. .:* ::: * :. * *. :: ..: .:.:**. : * ... * . . .:.*: .* . . . . .* * . *.... .. . . : : :. . . . . ", "identical_positions": 33, "similar_positions": 121, "identity": "10.38%" }, { "cls_id": "homologset.agr.SGD:S000002724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q562C4-1", "uniprot_id": "TMT1B_RAT", "id": "Q562C4-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDVLVPLLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YLMATLTARSYKKMESKKRELFS-QIKDLKGTSNEVTLLELGCGTGANFQFYPPG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDIEKAQFSEVQLEWQPPPFKWLPVGP------HIMGKAVK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DD20-1", "uniprot_id": "TMT1B_MOUSE", "id": "Q9DD20-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDALVLFLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YFMAMLTARSYKKMESKKRELFS-QIKDLKGTSGNVALLELGCGTGANFQFYPQG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLRPGGLLFFWEHVAEPQGSRAFLWQRVLEPTWKHIGDGCHLTRETWKDIERAQFSEVQLEWQPPPFRWLPVGP------HIMGKAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X9G9-1", "uniprot_id": "G3X9G9_MOUSE", "id": "G3X9G9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFP--------------------------------------------------------------------YFLKRFAMIYNWKMASLKQELFS-NLQEFAGPSGKLTLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLFKSVAENR-QLQFERFVVAVGEDMHQVTDGS-------------VDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTWNYFWQQVLARVWFLAFDGCNLTRESWKAIEQANFSKLNLQHIQAPLPLTLVRP------HIYGYAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8H3-1", "uniprot_id": "TMT1A_HUMAN", "id": "Q9H8H3-1", "name": "Thiol S-methyltransferase TMT1A", "aln": "------------------------------------------------------------------------------------------------------MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFP--------------------------------------------------------------------YFLVRFTVIYNEQMASKKRELFS-NLQEFAGPSGKLSLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLIKSIAENR-HLQFERFVVAAGENMHQVADGS-------------VDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRP------HIYGYAVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Y5-1", "uniprot_id": "E7F6Y5_DANRE", "id": "E7F6Y5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MSLFLNALAFICKVLTLPLFVGERVGLLS-FYKRLYP--------------------------------------------------------------------RLLSSFTIAYNELMNDKKRELFL-NLERFQPSKGSLRILEVGCGSGANFEHYPTG--SKITCTDPNPHFKTYLEKSMEKNE-HLVYDSFIVASGENLQAVEDSS-------------VDAVVCTLVLCTVKDTNKVLQEAKRVLRPGGAFFFLEHVVSDPSTWAYFFQHVLQPFWYYLQDGCEAIRATWKDIDNAGFSDVKLRHIQAPL-FFMIKP------HIIGYAVK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q726-1", "uniprot_id": "A0A8M9Q726_DANRE", "id": "A0A8M9Q726-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MSRFMDACALSFKVLILPLYIAEHVGLLS-FFKRVFP--------------------------------------------------------------------MIQYKATDWYNNKMNDKKRELFR-NLERFQPPEGSLRILEVGCGSGANFEHYPTG--SKITCTDPNPHFKKYLEKSIEKNE-HLEYDNFIVASGENLQAVEDSS-------------VDAVVCTLVLCSVKDTNKVLQESKRVLRPGGALFFLEHVVSDPSTWAYFFQHVLEPLWYFFGDGCEVTRATWKHIEAAGFSDVKLHHIQAPL-FFMLKP------HIVGYAVK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06668-1", "uniprot_id": "OMS1_YEAST", "id": "Q06668-1", "name": "Methyltransferase OMS1, mitochondrial", "aln": "MIVFRRFPTCLLHHIRQPASRSLLLESQRRSLSFTSYKYNSSHIDDDKSKKKLKNVFQMNSNRVIRKQKTKEELAKERFEEQLRSPNRFVRWGAIARSEKFSKGMTKYMIGAYVIFLIYGLFFTKKLFAKDKELERLLKKQEEGNANEYEALRIKELKGKLRRRDELKLEEYKKMQEEGIENFDDIRVQNFDQNKLNEQILPARDTTNFYQEKANEYDKAINMEERVIFLGKRRKWLMKHCQGDVLEVSCGTGRNIKYLDMSRINSITFLDSSENMMEITHKKFREKFPKYKKVAFVVGKAENLVDLAEKGKPSLENEKENQVKYDTIVEAFGLCSHEDPVKALNNFGKLLKPDGRIILLEHGRGQYDFINKILDNRAERRLNTWGCRWNLDLGEVLDDSDLELVEEKRTHLGTTWCIVAKRKGDVKKKDELGFVEKYLQSSIRKRMESFEKKDDMASKKELEPVPPVSKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :.. : . : : : : :: :* : . . :**:.**:* *::. . :* *.. :: *.. :: : *:*. .*:: : : . *.:* :: **: :. : *.: ::*:*.* : : :* . : :. . . : . : .. . * . * ", "identical_positions": 24, "similar_positions": 73, "identity": "5.1%" }, { "cls_id": "homologset.agr.SGD:S000002727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWT2-1", "uniprot_id": "D3ZWT2_RAT", "id": "D3ZWT2-1", "name": "", "aln": "------------------------------------------MEHLERCAWFLRGTLVR--AAVRRHLPW-----------VLVAAMLVGSALKELSPLPESYLSNKRNVLNVYFVKLAWAWTVCLLLPFIALTNYHLTG--KTSLVLRRLSTLLVGTAIWYMCTA---LFSNIEHYTGSCYQSPALEGIRQEHRTKQQCHREGGFWYG-FDISGHSFLLTFCALMIVEEMAVLHEVKTDRSHHLHV-----------------------------------AITTLVVALGFLTFIWVWMFLCTAVYFHDLIQKVFGTMFGLLGWYGTYGYWYLKSFSPGLPPQSSSLTLKQDTYKK---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59266-1", "uniprot_id": "FITM2_MOUSE", "id": "P59266-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "------------------------------------------MEHLERCAWFLRGTLVR--ATVRRHLPW-----------ALVAAMLAGSVVKELSPLPESYLSNKRNVLNVYFVKLAWAWTVCLLLPFIALTNYHLTG--KTSLVLRRLSTLLVGTAIWYICTA---LFSNIEHYTGSCYQSPALEGIRQEHRSKQQCHREGGFWHG-FDISGHSFLLTFCALMIVEEMAVLHEVKTDRGHHLHA-----------------------------------AITTLVVALGFLTFIWVWMFLCTAVYFHDLTQKVFGTMFGLLGWYGTYGYWYLKSFSPGLPPQSCSLTLKRDTYKK---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M3-1", "uniprot_id": "FITM2_HUMAN", "id": "Q8N6M3-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "------------------------------------------MEHLERCEWLLRGTLVR--AAVRRYLPW-----------ALVASMLAGSLLKELSPLPESYLSNKRNVLNVYFVKVAWAWTFCLLLPFIALTNYHLTG--KAGLVLRRLSTLLVGTAIWYICTS---IFSNIEHYTGSCYQSPALEGVRKEHQSKQQCHQEGGFWHG-FDISGHSFLLTFCALMIVEEMSVLHEVKTDRSHCLHT-----------------------------------AITTLVVALGILTFIWVLMFLCTAVYFHNLSQKVFGTLFGLLSWYGTYGFWYPKAFSPGLPPQSCSLNLKQDSYKK---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q52KL1-1", "uniprot_id": "FITM2_DANRE", "id": "Q52KL1-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "------------------------------------------MAAAVAGSLVDKLVCLWRQPYTRIYLPH-----------LFFCISLVGSVLKNAELVPESYFSSSRNVLNLYFVKVSWGWTIVLLLPFIAYSNFYIK---SHMFALRRLTSLLVATLVWYICTE---TFFYIEDITGSCYESNTMVVIRGEFDTKAACRKAGFFWDG-FDISGHSFILSYSSLVIMEEMVPMLHIQP---AYRNP-----------------------------------PLDCLYLALNVIVAIWIWMFGCTSVYFHDIIDKILGTSCGILGWYMTYKVWYVKLFSPGLPPQP-----KQHT------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRJ2-1", "uniprot_id": "FITM2_DROME", "id": "Q9VRJ2-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "MATKRRPLRPNLGGTAGSPSSSGSNMNFRPGGPDITRSEARGTRPTAAPTSIREILVMGVIHLCKKTIFFNTD----LKVALYLGSLFVISVIGDFVPFPKTYFARSDNLFNQYFVKIGWGWTLLFVVPFLVLSAYTITCGDHKRMLRHHFPRIVIATFFWFFWTK---LFNVVENSYGRCTT--------KGYATKSSCLKAGHLWKG-FDISGHAFILIHSSLVLIEEARPIIRWETIKEHIRNERHNRSTAENSGTNPLRTLNEEQMRSLQFLYKRLTPIIRTLFIGMAALQLLWDIMLVGTMLYYHRMIEKVISGIIAILTWYFTYRFWYPTPGLLPEAPGNGSFSYQREIPTFPFKRPSHLSTGAATTSSGSNSSRTNLNGKAATTGVPRDQQIPTFMGMPLFTSPKAASAAANLLMSDQQKRERDREQQTLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06676-1", "uniprot_id": "YFT2_YEAST", "id": "Q06676-1", "name": "Acyl-coenzyme A diphosphatase YFT2", "aln": "--------------------------------------MIRQLNYWSRKAYLIYPFQVFVGALLSIVVSSETLNHQKETCALLKSSNIFNVIFAYKANQLWPFLFFSLAFLQIYFHYLARMDILPLPISSTETSSSYLTYTNHWPLLKNRIISIMITQYACKFVLKYLLLFLNFQFIDHVFIWTGGECSSGSKTTSAEKCRLENGKWDGGFDISGHFCFLVSISMILWMELHLFSRFVQAEDMFWVVN---------------------------------KWVRACLAIVCAVLVIWICILWVTAIYYHTILEKVLGCLMGFICPVFIYHILPKIGILHNYLYL----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . .:: . .:: ** :. . : :. : :. : .:: ::: : * .: : * . * * ****** :* :::: * : . : : : :* :: * :*:* : :*::. .:: * ", "identical_positions": 20, "similar_positions": 56, "identity": "4.56%" }, { "cls_id": "homologset.agr.SGD:S000002728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TZ3-1", "uniprot_id": "AUXI_MOUSE", "id": "Q80TZ3-1", "name": "Auxilin", "aln": "----------------------------MTNPKSGVAESAGLACSRA------AAGENRMKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVSSYTKGDLDFTYVTSRIIVMSFPVDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKAITVSPVPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDIEVQPQDKVIDLTPPWEHYCTKDVNPSILFSSQQEHQDTLALGGQAPADLPPDHPRNLGQGGFFASLCWQDQKSEKSRCEEDHAALVNQESEQSDDELLTLSSPHGNAEGDKPHGAKKPGKKQQEPAAPPPPEEVDLLGLEGSDVSTNFSSLAAPPSNS--ELLSDLFGGVGATGPAQAGQAGVEDVFHPSGPVSAQSTPRRTATSASASPTLRVGEGATFDPFG-APA-KPPGQDLLGSFLNTSSAS-SDPFLQPTRSPSPTVHAS----------STPAVNIQP-DIAGGWDWH---TKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGS------SSFASKPTTPTGLGGGFPPLSSPQK--ASPQPMGGG----------WQQPAGYNWQ-QTQ----SKPQSSMPHSSPQNRPNYNVSFSAMPAGQSERG--KGSTNLEGKQKA--ADFEDLLSSQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATG---QPYEQYAKMIFMELNDAWSEFENQGQKPLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A6P4-1", "uniprot_id": "A0A8I6A6P4_RAT", "id": "A0A8I6A6P4-1", "name": "Auxilin", "aln": "----------------------------MLGFIS--------------------------------GASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVSSYTKGDLDFTYVTSRIIVMSFPMDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKAITVSPIPFFNKQRNGCRPYCDVLIGETKIFSTCTDFERMKEYRVQDGKIFIPLNITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDIEVQPQDKVIDLTPPWEHYCTKDVNPSILFSSQQEHQDTLALGGQAPADLPPDHPRNLGQGGFFASLCWQDQKSEKSRCEEDHAALVNQESEQSDDELLTLSSPHGNADGDKPHGAKKPGKKQQEPAAPPPPEEVDLLGLEGSDVSTNFSPLAAPPSNS--ELLSDLFGGGGATGPAQAGQVGVEDVFHPSGPASAQSTPRRATTSASASPTLRVGEGATFDPFG-APA-KPPGQDLLGSFLNTSNAS-SDPFLQPTRSPSPTVHAS----------STPAVNIQP-DIAGGWDWH---AKPGGFGMGSKSAATSPTGSTHGTPTHQSKPQTLDPFADLGTLGS------SSFASKPTTPTGLGGGFPPLSSPQK--ASPQPMGGG----------WQQPAGYNWQ-QAQ----PKPQSSMPHSSPQNRPNYNVSFSAMPAGQSDRG--KGSTNLEGKQKA--ADFEDLLSSQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATG---QPYEQYAKMIFMELNDAWSEFENQGQKPLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75061-1", "uniprot_id": "AUXI_HUMAN", "id": "O75061-1", "name": "Auxilin", "aln": "----------------------------MKDSEN-------------------------------KGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHYGQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNS--ELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFG-APS-KPSGQDLLGSFLNTSSAS-SDPFLQPTRSPSPTVHAS----------STPAVNIQP-DVSGGWDWH---AKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGS------SSFASKPTTPTGLGGGFPPLSSPQK--ASPQPMGGG----------WQQGGAYNWQ-QPQ----PKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERG--KGSSNLEGKQKA--ADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATG---QPYEQYAKMIFMELNDAWSEFENQGQKPLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6X2-1", "uniprot_id": "A0A8M9Q6X2_DANRE", "id": "A0A8M9Q6X2-1", "name": "Auxilin", "aln": "MSLLGGYKKKSSYDGYESLQLVDSSGDFSTGGRSGGGGGGGLTAVTLGSVKTGPARQDDYSTMDSSGPPSPDMDGNYGGGLLDMVKGGAGKFFSNIKDNLKDTIKDTSTKVMNQVATYTKGELDIAYITSRIIVMSYPAETVEMGYRNHTEDIRSFLDSRHADHYTVFNLSQRNYRGAKFSNRVSECNWPSRQAPSLHNLFAVCKNMYNWLKQNPKNVCVITCSDGRAPSGVLVCAMFCFCHLFANPVPAMQLLSAKRPGSGLWPSHRRYIGYVCSLVSEKPTVPHSKPLVIKTVTISPVPCFNKQRSGCRPFCDVLIGETKIFSTAQEYERMREHRIQEGKVVFPVGVSAQGDVVISVYHMRS---HALQAKVTNTQIFQIQFHTGFIAPGSTVLKFMKTELDACDSPEKYPQLFHVLIDIEVESTEKQKDLTPPWEQFPTKDLSPNVLFSCHQEHQDALAIADEMEG------------------LDLEDPAQGHSSCGGRVGP--NEESEPSDDEMLSLSSQQSNASNEKSKAAKRP-EPQAAAPPPPAAEEVDLLGLDGDAAKIPPSSPQPPANNTTTDLLGDLFG---APPTPQP----------ASCPGSAQSTPRRSAQSSSPGPSPRSGN--TFDPFGSGPAPAPKPQDFMGAFLGPGNMGQPDPFLHAARSPSPTMQNMGMGRSSPVPPSTPTVNIQQQNSTGAWEWNKPAAAGGGFGMGSKSASTSPTSSAHGTPTHQTKPNTLDPFADLGNLGAGLGGGGSGFSSKPTTPTGTGGAFPPMGSPQRPAPSPQHTASGGWHPNTGFPSWQAGGGAQWQPQAQGTPTKAPPASMPHTSPQNRPNYNVSFSAMSGASPGAAGPKAQPNMGTRPKVSDANFDDLLSGQGFAGGKEKKGPKTIAEMRKEEMAKEMDPEKLKILDWIEGKERNIRALLSTMHTVLWEGETRWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATG---QPYEQYAKMIFMELNDAWSEFESQGQKALY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06677-1", "uniprot_id": "SWA2_YEAST", "id": "Q06677-1", "name": "Auxilin-like clathrin uncoating factor SWA2", "aln": "----------------------------------------------------------------------------------------MSDPFAHLLTSLKNKDSASASKETTPQSSNSP------------SITGSAVADVARTDKSPNDSLHSISAP------------------------------PLIPSPKVD---------FSAPPLVPTNSTTKSNTANNTPPSALANTDDDFNQLFG-MGTVTTTDTIQKPDEDYYGSKEDHLYNGDDALVDEVKDMEIARLMSLGLSIEEATEFYENDVTYERYLEILKSKQKERNDLAIRKKESGIKMEKSGLSNIVGTDSN-------------------------------------NLFSMATDFFNKGKKLVDQWTSFPPEANDRLNNYSKTHDKVEDYDLP-----QVNDSPNRILFEDNEVVENLPPADNPDQ-------------------DLLTDFETKIDITKRTAPDVSHSSSPTSGILIEENSRRN-----------------------EPLIEDSLLDFSEGNLTNSKSNEDSTLFNE-----------------------------------------NSNTDSTIPISDIELSGYNEFKAKG---TSLFKNGDYINSLQEYEKSLNTLPLNHPLRIIALSNIIAS------------------------------QLKIGEYSKSIENSSMALELFPSSKAKWKNKISNSDPERSFNDIWP-------------KIMIRRAESFEHLESFKKALETYQELIKK--------------------------------NFFDDKIMQGKRRCQDFINPPPVKKSMPVKKKTTTTSPATKKQ------NLTASSSNSPISVDSTSEIKKRELENAKLALYDKVFEKISSWKDGKDDDIRHLLANLSSLLTWCN--WKDVSMQDLVMPKRVKITYMKAVAKTHPDKIPESLSLENKMIAENIFSTLSIAWDKFKLQNDIN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::: .**:. . :::: :: : : . . * :. :.::*: . * :*.:. :. *.* . ..:... *. : * :*:. .. ::*. . *:. :: . : :: . * :::. . * :: . : ::* .: * . :: :::.. : :. : : . .* : . * .:* : :: :. :* * * : .*. :: .:* : *. ..: . : .. ...*. :.. :: .* :. . : .**.:. . . * .. * . : *: . . . . *.. * : * :.:: . . *: :. * : : * :. . :.:: : . .... :.* .. ** .:. : . . . .* : * :: : * : .. *.: . : :.. . . * .. * :* :... . .. .. . :: * ** .* :**: :** **:.: ::* : ** *.* *** *::** .* :** .**** . : *: ** *. **.:*: *.: ", "identical_positions": 86, "similar_positions": 238, "identity": "8.42%" }, { "cls_id": "homologset.agr.SGD:S000002729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VH61-1", "uniprot_id": "Q9VH61_DROME", "id": "Q9VH61-1", "name": "asparaginase", "aln": "------MPAAKCGCLKKEARVHVIYVGGTIGMIRN--ESGVLHTAPKVLARQLQEFPSCHDR-NYTSKDNDGPMMVLPAVSGAPYRVLYDLIEFCPLMDSSCMGFCDWK----------RIANEVGKTYKSYDGFVILHGTDTLAYSASALAFMLESLNKPVVFTGAQIPIFEARSDGRENFLGALLIAGNYSIP--EVLVFFGNKILRGCRSTKLNSDSFHALDSPNFAPLGRASVNIEINSRQIFRPCNIKPFSLHSELEKN----VALLRIYPGISASVVQAILKEPTKGVVLQTFGAGNFPVNREDLLDELREAVHRGVIIVNITQCSAGMVANIYETSQGLMEVGVIPGYDMTQEAAFTKLAYVLSKPEWDIPNKKKVMLLSLRGELTTNKVAKINDIDLIEGVARTLHMSTAMERQQMCSTFYPALVAAAVTEGDVHKLGDLKQYGANLCDTNCDGRSAMHLACFLGKLNCVCFLISAGCPVNVHDRFNRTPLHEAIDTDNHDIINALLKNGAKLNDQPLVQAELLRALTERGKIKRLESFRLAGANLTLADRTGRTALHYACQLGNHEVVDYLLPHYENPYIKDELGMSPIDYAKAANHAHILTLMRFKEKELAKKDPCSCTQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38986-1", "uniprot_id": "ASPG1_YEAST", "id": "P38986-1", "name": "L-asparaginase 1", "aln": "MKSDSVEITTICPDVENSQFVVQSNCPETIPEILKSQNAAVNGSGIACQQRSLPRIKILGTGGTIASKAIDSSQTAGYHVDLTIQDLLDAIPDISKVCDIEYEQLCNVDSKDINEDILYKIYKGVSESLQAFDGIVITHGTDTLSETAFFIESTIDAGDVPIVFVGSMRPSTSVSADGPMNLYQAICIASNPKSRGRGVLVSLNDQISSGYYITKTNANSLDSFN-VRQGYLGNFVNNEIHYYYPPVKPQGCHKFKLRVDGKHFKLPEVCILYAHQAFPPAIVN-LVADKYDGIVLATMGAGSLPEEVN------ETCMKLSLPIVYSKRSMDGMVPIANVPKKGSKEDNLIASGYLSPEKSRILLQLCLAG-NYTLEEIKHVFTGVYGG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :::. * ** * : ::.* :. *.* .: . :** *.. . *. : :* : ::. : * . :*: . :* : *.:: :::**:** ******: :* : ::: : *:**.*: * .. :** *: *: **.* . *** :.::* * ** *::*:.::: . . **. * .:* . : *.*: : :: *.:* : .:..::*: :: : .*:** *:***.:* : : . .:: .: ** .:. ***. ..:* * .:*.. :: * : * *: :: : : *:*: * ", "identical_positions": 80, "similar_positions": 128, "identity": "12.7%" }, { "cls_id": "homologset.agr.SGD:S000002730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2M0-1", "uniprot_id": "RM38_MOUSE", "id": "Q8K2M0-1", "name": "Large ribosomal subunit protein mL38", "aln": "MAAPWWRAAFFGIGRCRGFSTSAFLSRRTPPLGPMPNEDIDVSNLERLEKYRSFERYRRRAEQEARAPHWWRTYREHFVKETDPKDKIDIGLPPPRVSRTQKLLERKHFLRELRANVEEERAARLR----TASIPLEAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGAT-FVPWVPLHVAYAVGEEDLIPVYHGNEVTPTEASRAPEVTYE----------ADKDSLWTLLFINLDGHLLEP--DAEYVHWLLTNIPS---------NRVAEGQETCPYLPPFPARGSGFHRFAFLLFKQDKPINFSEDTRPSPCY-QLAQRTFRTFDFYKRHQEAMTPAGLAFFQCRWDDSVTHTFHQLLDMREPVFEFVRPPPYHPKQKRFPHEQPLR-YLDRYRDSHEPTYGIY-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQN9-1", "uniprot_id": "RM38_RAT", "id": "Q5PQN9-1", "name": "Large ribosomal subunit protein mL38", "aln": "MAAPWWRAAFSVTGRCRGISTSASLSRRTPPLGPMPNEDIDVSNLERLEKYRSFERYRRRAEQEAHAPHWWRTYREYFLKETDPKDRINIGLPPPRVSRTQKLQERKRFLQELRANSEEERAARLR----TASIPLEAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGAT-FVPWVPLHVAYALGEEDLIPVYHGNEVTPTEASQAPEVTYE----------ADKDSLWTLLFINLDGHLLEP--DAEYLHWLVTNIPS---------NRVAEGQESCPYLPPFPARGSGFHRFAFLLFKQDKPINFSEDTRPSPCY-QLAQRTFHTLDFYKKHQEAMTPAGLAFFQCRWDDSVTHTFHQLLDMREPVFEFVRPPPYHPKQKRFPHQQPLR-YLDRYRDSHEPTYGIY-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DV4-1", "uniprot_id": "RM38_HUMAN", "id": "Q96DV4-1", "name": "Large ribosomal subunit protein mL38", "aln": "MAAPWWRAALCECRRWRGFSTSAVLGRRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREYFGEKTDPKEKIDIGLPPPKVSRTQQLLERKQAIQELRANVEEERAARLR----TASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGAT-FVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYE----------AEEGSLWTLLLTSLDGHLLEP--DAEYLHWLLTNIPG---------NRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSEDARPSPCY-QLAQRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLR-YLDRYRDSHEPTYGIY-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY48-1", "uniprot_id": "Q9VY48_DROME", "id": "Q9VY48-1", "name": "Large ribosomal subunit protein mL38", "aln": "------------------MSFSNLLMKSGLTVAVRDAQAAVLMTATRQG-------HTIRGKPPGVARSLEQRIREENVEDPEVVARINIGFPQLKESRSAQLKKRLEHLKSQRSDKQLEQLARSN----KLIIDLDKVQRTYVKTTGQHDLRLVADHYGIFEHLFGSAY-FVPRVPLNISYQLDGDSLAPVYNGNVIKPTEAAKAPQIDFDGLVDPITGQAAGQDTYWTLVASNPDAHYTNG--TAECLHWFIANIPN---------GKVSEGQVLAEYLPPFPPRGVGYQRMVFVLYKQQARLDLGSYQLAAADYGNLEKRTFSTLDFYRQHQEQLTPAGLAFYQTNWDESLTQFYHDVLKIKEPVYEYDFPKPYLTDQKFFPLKQPFNLYMDKHRDQKQVNKEYLERKLAKTHPFEGPKKPLRYPNAHPIRDVPSWLRTEIRKERLGTGRVQDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54185-1", "uniprot_id": "OBA5_DROME", "id": "P54185-1", "name": "Putative odorant-binding protein A5", "aln": "-----------------------------------------------------------------------------------------------------------------------MKLPALH----LLFLGFICLARSQDNDE---NVRRIMKEMEVIPEILDEP----PRELLRIKY----DNTIDIEEGKTYTPTELKFQPRLDWN----------ADPESFYTVLMICPDAPNRENPMYRSWLHWLVVNVPG---------LDIMKGQPISEYFGPLPPKDSGIQRYLILVYQQSDKLDFDEKKMELSNADGHSN--FDVMKFTQKYEMGSPVAG-NIFQSRWDEYVPELMKTLYGVSE-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06678-1", "uniprot_id": "RM35_YEAST", "id": "Q06678-1", "name": "Large ribosomal subunit protein mL38", "aln": "MLRRSIHTTKILQKPNATSHIWSDFTTRPSSLSIQSSKVKNYLFQKKASLDPPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYELANKTKNPLKKDALLIKAEINNPEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWIEPGEFLSSNVTSMRPIFKIQEY-----ELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNIIADYLPPVPEKNAGKQRFVVWVFRQPLIEDKQGPNMLEIDRKELSRDDFDIRQFTKKYN--LTAIGAHIWRSEWDAKVAAVREKYGLPPGRVFSRVRR-----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : * :.: : : *: ... * . : :*:: * . : : :.*: . ..: . *: *.* :. * :* . :::* : . * .* :::: . * ::: .** :. . ", "identical_positions": 17, "similar_positions": 55, "identity": "3.72%" }, { "cls_id": "homologset.agr.SGD:S000002731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZL11-1", "uniprot_id": "D3ZL11_RAT", "id": "D3ZL11-1", "name": "", "aln": "---------MASLDDAGEVREGFLCPLCLKDLQSFYQLQSHYEEEHSG-----------------DRDVKGQIKNLVQKARKAKNKLLKRE----------------GDDRVEPGTQGYESFSYGGVDPYMWEP----------------------QELGAMRSHLSDFKKHRAARIDHYVIEVNKLIIRLEKLTA------------FDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELIGLPLAN-KLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDERIRCCTHCKDTLLK-REQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYS--------LEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTMERQAALESRRKLEERQSGLASHTANGDMRSLQGIPAPLRKAEGWLPLSEGQVQSEDPDPLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEELQREQLQMLRQRELEREEEQFLAASLQTRTRVLELREVLPFQLEPIRGPHTDLAYSLDEDSSPVQSSTAPDILSPGSALAPIHVWSGSPALSQELLLQSTISQPSSKTSLNPFDEEDLSSPIEGAVS-PAAVEAFLGPPAAVTKEYNPFEEDAEEEEVAELGAGNPFTDPDSPAPNPFDEDD-HP--RSASPAAPGNPFEECPCTNPFEVDSDSGMEAEEHIEEELLLQQIDNIKAYIFDAKQCGRMDEVEVLTENLRELKCTLAKQKGAPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y56-1", "uniprot_id": "RBNS5_MOUSE", "id": "Q80Y56-1", "name": "Rabenosyn-5", "aln": "---------MASLDDPGEVREGFLCPLCLKDLQSFYQLQSHYEEEHLE-----------------DRDVKGQIKNLVQKARKAKNKLLKRE----------------GDDRVEPGTQGYESFSYGGVDPYMWEP----------------------QELGAMRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTA------------FDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELIGLPLAH-KLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDKLLK-REQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYN--------LEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTVERQAALESRRKLEERQSGLASHTANGDVRSLRGIPPPLRKAEGWLPLSEGQGQSEDPDPLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYDQQQTEKAIELSRKQAEEEELQREQLQMLRKRELEREQEQFLAASLQTRTRVLELREVIPFQLEASRGPHIDLSYSLDQDSSPVQSSTAPDILTPGSALAPMHLWSGPPALGQETLPQSTMSQQSDKASLNPFDEDDLSSPTEGAIS-PAAVEAFLGPPAAVTKEYNPFEEDAEEEEVAELGAGNPFTDPDSPAPNPFDEDD-GP--RPASPAAPGNPFEECPSTNPFEVDSDSGMEAEEHIEEELLLQQIDNIKAYIFDAKQCGRMDEVEVLTENLRELKCTLAKQKGAPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1K0-1", "uniprot_id": "RBNS5_HUMAN", "id": "Q9H1K0-1", "name": "Rabenosyn-5", "aln": "---------MASLDDPGEVREGFLCPLCLKDLQSFYQLHSHYEEEHSGE----------------DRDVKGQIKSLVQKAKKAKDRLLKRE----------------GDDRAESGTQGYESFSYGGVDPYMWEP----------------------QELGAVRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTA------------FDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELISLPLAN-KLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDTLLK-REQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYS--------LEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPS-LSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPAAGVSLDPSARILKEYNPFEEEDEEE---EAVAGNPFIQPDSPAPNPFSEEDEHPQQRLSSPLVPGNPFEEPTCINPFEMDSDSGPEAEEPIEEELLLQQIDNIKAYIFDAKQCGRLDEVEVLTENLRELKHTLAKQKGGTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLS5-1", "uniprot_id": "Q9VLS5_DROME", "id": "Q9VLS5-1", "name": "", "aln": "MSGNPFDSDEDQSSASGEILEGFLCPICRADLKSIDVLTDHFARQHAE-----------------EEDALKSFKDIFTKAKKKILNPFEDEKGASVSSPAGSSSSAAGKNPNGNGDRNGPSNARSRLNVFNYMAR---------------------QQPGAECSHFEYFQSIRNPRLERYASETNKLIIRLHRL--------------LKDLPADSVQRRQHEQQTVAWLDGSSVKLCPSCAKSFHIARRQHHCRLCGGIMCNDCSKFLPLEDAM-QLASLS-------TTRSEPLQQLH-------------------QHENAIRLCEHCLWLLDT-RKDMHESRTCRPLLVQVYEQIRQLQKEVTPDLDMYLKIINSLNEGDTIFT--------LADAGALRGKIGQVAEAMDMRSKRILAIFCE----PGSREEALKKAIRLGCIQAIKERMLSLPPLPEESHIRQMQERRRMETEQRILTEQRMAMEAYERNNMAANQSNVGVPGPESGSFAQG-SDLQSLNNWSAPQAASKSSLD-DPLIEQINIIKGYIKQARQDMNFEVVETLELNLRELQREVYERQRQSQGSTAASPTEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32609-1", "uniprot_id": "PEP7_YEAST", "id": "P32609-1", "name": "Vacuolar segregation protein PEP7", "aln": "-----------------MDLENVSCPICLRKFDNLQALNAHLDVEHGFNDNEDSLGSNDSRLVNGKQKKARSVDSSAQKLKRSHWEKFKKGKSCCHTCGRTLNNNIGAINCRKCGKLYCRRHLPNMIKLNLSAQYDPRNGKWYNCCHDCFVTKPGYNDYGEVIDLTPEFFKVRNIKREDKNLRLLQLENRFVRLVDGLITLYNTYSRSIIHNLKMNSEMSKLERTVTPWRDDRSVLFCNICSEPFGLLLRKHHCRLCGMVVCDDANRNCSNEISIGYLMSAASDLPFEYNIQKDDLLHIP----------------------ISIRLCSHCIDMLFIGRKFNKDVRMPLSGIFAKYDSMQNISKVIDSLLPIFEDSLNSLKVETAKDSENTLDPKNLNDLARLRHKLLNSFNLYNTLTRQLLSVEPQ-----SHLERQLQNSIKIASAAYINEKILPLKSLPAILNPEGHKTNEDGQKAEPEVKKLSQLMIEN-----------------------------------LTIKEVKELREELMVLKEQSYLIESTIQDYKKQRRLEEIVTLNKNLEELHSRIHTVQSKLGDHGFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. **:* .:..: * * :* ... .... * :: . :: . : * . :. :: * . * . * : : . :* *: :* : . : *: ...* :. .* :* *.: * : *:******* ::*... . : * * : . .: : ** * ** * *: : : . :. *:.:: : : : **: : . * . ** :: : : : ::::*:: : *:. *: .. ::*::* * .** : . : .. : . : : . . . : * :* * . *:: : . : : **: **.:*: . * : ", "identical_positions": 63, "similar_positions": 129, "identity": "7.22%" }, { "cls_id": "homologset.agr.SGD:S000002732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2N2-1", "uniprot_id": "UTP4_MOUSE", "id": "Q8R2N2-1", "name": "U3 small nucleolar RNA-associated protein 4 homolog", "aln": "---------------------------MGEFKVHRVRFFNYVPSGIRCVAYNNQSNR---------LAVSRTDGTVEIYNLSANYFQEKFFPGHESRGTEALCWAGGQ----RLFSAGLNGEILEYDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVT--PEKIQFARNFDRQKSRILSLCWHPAGTHVAAGSLDYISVFDVK-SGSIIRKMVLDRQHLGVTKSRCIVWGVAFLS-DGTVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFVVGTAEGTVFHFQLVSMT--SNSSEKQWVRTKPFQHHTHDVRAVAHS----PTALISGGTDTHLVIRPLMERVEVKNYDAALRKITFPHRRLISCSKRRQLLLFQFAHHLELWRLGSTSATGKNG-----------DTLPLSKNADHLLHLKTKGPENIICSCVSPCGSWIAYSTASRFFLYRLKYERDNISLQRVSKLPSFLRSALHILFSEDSTKLLVASNQGSLHIVHLSEG-----SFKHLHTFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPAYNFP--VTALAIAPNTNNLVIAHSDQQVFEFSI----------PEKQYTEWSRSLQK--------------------QGFHQLWLQRDTPITHISFHPKRPMH------------ILLHDAYMFCIIDKS-------LPLPNEKTVLYNPLPPKNESDVFLRR-TTHGFKMSKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969X6-1", "uniprot_id": "UTP4_HUMAN", "id": "Q969X6-1", "name": "U3 small nucleolar RNA-associated protein 4 homolog", "aln": "---------------------------MGEFKVHRVRFFNYVPSGIRCVAYNNQSNR---------LAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQ----RLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQIT--PDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVK-SGSAVHKMIVDRQYMGVSKRKCIVWGVAFLS-DGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVT--SNSSEKQWVRTKPFQHHTHDVRTVAHS----PTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNG-----------DTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGG-----SFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFP--VTAMAIAPNTNNLVIAHSDQQVFEYSI----------PDKQYTDWSRTVQK--------------------QGFHHLWLQRDTPITHISFHPKRPMH------------ILLHDAYMFCIIDKS-------LPLPNDKTLLYNPFPPTNESDVIRRR-TAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06679-1", "uniprot_id": "UTP4_YEAST", "id": "Q06679-1", "name": "U3 small nucleolar RNA-associated protein 4", "aln": "MSSSLLSVLKEKSRSLKIRNKPVKMTSQERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEIWNPRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVLIDISGGPGVLEHDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRIWSAQKNDENMGRLLHTMKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRKIFQFSQNTNK--SQKNNR-WVNSSNRLLHGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTS---FSNGNYRKMPTVEPYSKNVLVNKEQRLVVSWSESTVKIWTMGTDSSTEQN--------------------YKLVCKLTLKDDQNISTCSLSPDGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDN-DLLLRTSTKLVKFIDNSKIVICSCEDDVFIVDLESEEDEKPQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVISRGCGVVDILDLKARISKPLARLNNFITAVHINTSRKSVVVITADNKIYEFNMNLNSEAENEDSESVLTQWSKNNTDNLPKEWKTLKENCVGIFSDIENSSRLWFWGATWISRIDFDVDFPINKRRKQKKRTHEGLTITDESNFMNDEEDDEDDDIDMEISENLNVLLNQGNKIKSTDVQRNEESSGHFFFTDKYKPLLFVDLISSNELAIIERNPLTFHSKQKAFIQPKLVF--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PFG1-1", "uniprot_id": "M9PFG1_DROME", "id": "M9PFG1-1", "name": "", "aln": "----------------MTNNAKKEPQQRGKHQVHNVRFYTIKPREIVSLAYSKSSKC---------LALSRATPVIELWNLEHAPYLDRVIHLPTDSHVESIAWAGNR-----LFSVDLSGKLIEWDVIKLKQRYEHSPTGNALWSIDVNPAETDIAIGSEEGHINILSIE--NDEITYKSLFNKQKGRVLCIKFDKTGTKLVTGTEGFVRIWNVL-KGTTLHTMTLS-------EKNVIVWSLQVLS-DNTIIAGDSAGFVTVWDADNATQIDSTRVLDKNVFALAVNNKEDRLVCSGMQPPLIRIFSKTKIKREESTSERWIKFLQRDAHKHYVKSLLVID----DQIYSGGRDGILTITSSER-----MQAHLSQHAPFLKGSVASMAISKKLLLLRYPNSVHLWRLGSVAPQGEDKKKPWALPVGHTEEQLLELPPQKLLQLNVKEHNFIQSAAISSDANWICYSTLKELRISRLKSDPLQVER-LVDDLPEELQPASHIIFTKQGDLVLLNPQNNHLSWFTLEED-----LVTFKYTIDLSEKCKNTISHVVISSHGEYIVAASSDHIISVWKLHGKQYKHLLNLPRHRAGTTALSMHEDYPRVVVAYANGQLVEYDL----------VNRIFTCETN--------------------------EYLIPETRRHCINGISLDPQNRNI------------FIVHTEGNLYVLERDQHLDPKELVSNSKSKKLSN--GNRSSVDGGSKGLSLKTTLSRQVRLHLVHVSRLSPNELVNVSISTNNLLAPLPPPYQRKKFGAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **. ** * * .:*:.:.*: **:.*: :*::* : : .: . *.:.*: . *** . . : *:*: . .. :**: . : .: :*.::* : ::.: : . : :*:.*:* : :. . : : . : ::.. .. : : : :**.: *. . : : **.* : .** .* .* : :* .::. .:: .. . : :::: . .:.... *:. * : :::: : *** : *.: . ::*:: :.:* :*: . :: . : :*. * : * ..:*. .. : . . : :*: ::. :.. *:.: ::: :. :.: . :. : . *. . . :. :. : . * .: : : . **: : . :*: :: :: *:.: : * :. : *. *.:. . : : : :.. : .. . * * .. * . : . *:.:. :. . *. :. : : . : * . ", "identical_positions": 68, "similar_positions": 236, "identity": "8.45%" }, { "cls_id": "homologset.agr.SGD:S000002733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD72-1", "uniprot_id": "D3ZD72_RAT", "id": "D3ZD72-1", "name": "", "aln": "------------------MAAQKKRLSVKEAFQLAQQPHQN-------------------QAKLVVALSRTYG-------AVNDKTAFQEEFVHYLKYAMVVHKREPAVERVMDFTAKFVTSFH---------QSDQEEEEEEKDGGILNYLFTFLLKSHEANSSAVRFRACQLINKLLGNMPENAQIDDDLFDKINEAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DHDCPVVDAYVTLIENDSNPEVRRAVLSCIAPSAKTLPKIVERTKDIKDIVRKLAYQVLAEKVHMRALSIAQR---VLLLQQGLSDRSDAVKQAVQKHLLQGWLRFTEGNILELLHRLDVENSSD-------VAVSVLHSLFSMSPLSELVG---ICKDDDGRKLIPVETLTPEIALYWCTLCEYLKSKGDEGEEFLEQILPEPAVYAEYLVSYIQGFPVVNEEQKSDFTYIGNLMTREFIGQQLILIIKSLDTSEEGGRKRLLAILQETLTLPTTPISLFSFIVERLLHIVTDDSKRIQIVTEIISEIRAPIVT--------VHVD--PSDTRK-KELKMAEIKVKLIEAKEALENCIAVQDFDQASKLKEEIKTLEDARINLLK-----ETEQLEIKEVQTEKNDVETLQKCFILCYELLKRMSISTGIGATMNGIIESLILPGIISVHPIVRNLAVLCLGCCGLQDQNFASKHF-ILFLQVLQIDDVTIKVSALKAIFDQLMMFGIEPFKAQKVKAVHCEGAE-------LSSPDEQEE-DAEDRATAKSVLKLLSDFLDSEVS-ELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNP--------------------------------------------------------------VTEEDVRLRHCLGVFFPMFAYASRTNQECFEEAFIPTIQTLANAPASSPLAEVDVTNVAELLVD---------------------LTRPSGLNP-QAKNSQDYQALTVHDNLAIKICNEILTNPCS----PENRVYTKALSLVELSSS-----------------------------------VTKDLLLLLDEILEQVTDRTCLRALEKIKIQLGKGSKEF-DQCVVTEDANTTTKVLQDENE------------------------------------------------------------------------YRTPARNVKGTQASKSTQGKTNRGRRKAPVSSKTNRRCQTAGPDSESDHEPP---SEMRMRLPRRAKTAALQKSKLNLAEFLNEDPS----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PWG6-1", "uniprot_id": "E9PWG6_MOUSE", "id": "E9PWG6-1", "name": "", "aln": "------------------MAAQKKRLSVKEAFQLAQQPHQN-------------------QAKLVVALSRTYG-------AMDDKTAFQEEFIHYLKYAMVVYKREPAVERVMDFTAKFVTSFH---------QSDEEEEEEENDGGILNYLFTFLLQSHEANSSAVRFRVCQLTNKLLGNMPENAQIDDDLFDKINEAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DDDCPVVDAYVNVIENDSNPEVRRAVLSCIAPSAKTLSKIVGRTKDIKDTVRKLAYQVLAEKVHMRAMSIAQR---VLLLQQGLNDRSDAVKQAVQKHLLQGWLRFTEGNILEFLHRLDVENSSD-------VAVSVLHSLFSMTPLSELVG---ICKNDDGRKLIPVETLTPEIALYWCTLCEYLRSKGDEGEEFLEQILPEPAVYAEYLLSYIQGFPVVNEEQKGDFTFIGDLMKREFIGQQLILIMKSLDTSEEGGRKRLLAILQETLILPTTPISLVSLIVERLLHIIRDDNERIQIVTEIISEIRAPIVN--------VVVD--PSDTRK-KELKMAEIKVKLIEAKEALENCIAVQDFDQASKLKEEIKILEDAKINLLK-----ETEQLEIKEVHTEKNDAETLQKCLVLCYELLKQMSTSTGITATMNGIIESLILPGIISVHPIVRNLAVLCLGCCGLQNRDFASKHF-MLFLQVLQIDDVTIKISALKAIIDQLMMFGIEPFKTQKVKGVQCEGEE-------INCHDKQEENDAGETDPAKSVLKLLSDFLDSEVS-ELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNP--------------------------------------------------------------VTEEDVRLRHCLGVFFPMFAYANRTNQECFEEAFIPTVQTLANAPVSSPLAEVDVTNVVELLVD---------------------LTRPSRLNP-KAKNSQDYQALTVHDNLAIKICNEILTSPCS----PENRVYTKALSLVELSSN-----------------------------------VTKDLLLLLDEILEHVTDRTCLRALEKIKSQLGKGGKES-DPGVVTQDVNTTTAVLQNENE------------------------------------------------------------------------YMTPVRDGKGTQTSKSTQGKSKRGCRKAPVSSKTNRRRQIAGPDSESDHEPP---SEMKMRLPRRAKTAALQKSKLNLAEFLNEDTS----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPX3-1", "uniprot_id": "CND3_HUMAN", "id": "Q9BPX3-1", "name": "Condensin complex subunit 3", "aln": "------------------MGAERRLLSIKEAFRLAQQPHQN-------------------QAKLVVALSRTYR-------TMDDKTVFHEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFH---------QSDMEDDEEEEDGGLLNYLFTFLLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPK-----------DDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMSIAQR---VMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSE-------VAVSVLNALFSITPLSELVG---LCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIRAPIVT--------VGVNNDPADVRK-KELKMAEIKVKLIEAKEALENCITLQDFNRASELKEEIKALEDARINLLK-----ETEQLEIKEVHIEKNDAETLQKCLILCYELLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHF-VLLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTE-------INSDDEQESKEVEETATAKNVLKLLSDFLDSEVS-ELRTGAAEGLAKLMFSGLLVS-SRILSRLILLWYNP--------------------------------------------------------------VTEEDVQLRHCLGVFFPVFAYASRTNQECFEEAFLPTLQTLANAPASSPLAEIDITNVAELLVD---------------------LTRPSGLNP-QAKTSQDYQALTVHDNLAMKICNEILTSPCS----PEIRVYTKALSSLELSSH-----------------------------------LAKDLLVLLNEILEQVKDRTCLRALEKIKIQLEKGNKEFGDQAEAAQDATLTTTTFQNEDEKNKE-------------------------------------------------------------------VYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEADSESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z987-1", "uniprot_id": "A1Z987_DROME", "id": "A1Z987-1", "name": "Nuclear condensin complex subunit 3 C-terminal domain-containing protein", "aln": "MAKPKAKAGETEKPKTKAAGGKKRLAATKKTKKDGEKENEDQSVATTSDTSAELMYAIMRQAELKESLHKRYSKEMQQLYAKMGHESFRKAFINVLKAVLGAEEGNENANMALNFCATFVTSSD---------SDGTEP--------MLAETFHWLLTTYSSNP-HIRYRICYFVNLILKELGPNAALDDHQCDDILEAMLDRVKDVSASVRKQAVLAMQRLQNPD-----------NPSDVVVGAYMYHLTSDPSPNVRQCIITCMGRNYITIPHILERLWDVDEKVRRHTYVNMCN-YPVRSYKVAQR---LTLLEQGLNDTSATVRKTVINFMLKTWIESYQQNYVALIAALKLDSNEEELLRFRRVAKQMLRVIFQQTDIKQLIDQLPLSEDCELHRCIPHDSVTVELLLYWQCLSEYLETEAPE----IESLLPELSVFCTYMDKFCQ-FQKPDMDKFAQVEFQNMLLS-------LVEILETYDLGDEIGRGNMRLLITNLLKDCLLDHKIVRVLVRCMEQLITDTNDRIQYFIEIIYELCELNTKQNDLIHDRSLINKLLDDLDTPLKMKISSLKVKILELEELEGNYVRQREYIRAQSVNDEKIAVTEEYTELIRPL--LEKHGVIEMPTRPKLSKQERVLKGLYISYYMTASPHVHK-LTPSLCQLYKDFICRYLPCAEVDIFEWSIKCGTTFSIFYEAYSREVFEVVVVQFCKNNNVRLCEASANCILELLDRYGVDYFNDLNQTGGSLSKTKRRQLYTMQELYDDDDGSQSQNNEQNSDILVVLGHYLERVQHRGVGMAIVRGLCRLVLRGHVDDRTDVLELLLKRYFNPNTEPIINQVLGLFFEELRRLNKHSLLQPCFLPTVWTCNYDSPLHGVQPEHLTKFFLEMTVQEMSTPQTNIHNKIAISFLQYIQNYFTERKDMCRLLAKELTNLSINVLNGPEVKAELLALAENLIQSELDPRMIKCIQNFKLVVNGSFNPPPRRNPDEGESDEEYETATVTTAESETAVPAQSQPPVTEES-PNDVTQSAAITAVDATETPKAAAPPAPVPEPIVTTFGKDNIVGIRHLRRSMAISHSDAESLLGPQSPNPEESTESEAVETSKQNLRQPQMRRRLEMAIARSSKTPEKQPSTEEESSDEEISESPNAANKSNDSEVIEASPTAASPSPRAGHEASHLRIRSLRIRKVASTSTSQTTPKPVSKRKVVHLETPLRNGRKRVLRRSPSNSNSRSLRSRDSTALSSPRVSPRRKQQRLDNRSTRRQQMTKNTNSPTDSTSSVKENQIPPVIVIELDSDTESESNAKPESTPPKKPLKKTIPLIRSRPSSSTPKVTTRNEARAQRMNSKVMTRKRMSLEMNLSGGQLQVSTPKRVTRAVALSMSTDGKRSRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06680-1", "uniprot_id": "CND3_YEAST", "id": "Q06680-1", "name": "Condensin complex subunit 3", "aln": "-----------MQDPDGIDINTKIFNSVAEVFQKAQGSYAG-------------------HRKHIAVLKKIQS----KAVEQGYEDAFNFWFDKLVTKILPLKKNEIIGDRIVKLVAAFIASLERELILAKKQNYKLTNDEEGIFSRFVDQFIRHVLRGVESPDKNVRFRVLQLLAVIMDNIG---EIDESLFNLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHLTELSDNEENFEATRTLVASIQNDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLVYSRILKSMGRKCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELLEKLDVSRSSV--------CVKAIEALFQSR--PDILS--KIKFPESIWKDFTVEIAFLFRAIYLYCLDNNIT-------EMLEENFPEASKLSEHLNHYILLRYHHN-DISNDSQSHFDYNTLEFIIEQLSIAAERYDYSDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSINEKDFVTMAIEIINDIRDDDIE----------------KQEQEEKIKSKKINRRNETSVDEEDENGTHNDEVNEDEEDDNISSFHSAVENLVQGNGNVSESDIINNLPPEKEASSATIVLCLTRSSYMLELVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKLAIDNMYILGMCVSK-GNASLKYIALQVIVDIFSVHGNTVVD-------------------------------GEGKVDSISLHKIFYKVLKNNGLPECQVIAAEGLCKLFLADVFTD-DDLFETLVLSYFSP--------------------------------------------------------------INSSNEALVQAFAFCIPVYCFSHPAHQQRMSRTAADILLRLCVLWDDLQSSVIPEVDREAMLKPN--------------------IIFQQLLFWTDPRNLVNQTGSTKKDTVQLTFLIDVLKIYAQIEKKEIKKMIITNINAIFLSSE-----------------------------------QDYSTLKELLEYSDDIAENDNLDNVSKNALDKLRNNLNSLIEEINERSETQTKDENNTANDQYSSILGN---------------------------------------------------------------SFNKSSNDTIEHAADITDGNNTELTKTTVNISAVDNTTEQSNSRKRTRSEAEQIDTSKNLENMSIQDTSTVAKNVSFVLPDEKSDAMSIDEEDKDSESFSEVC-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. : .: . : : * : . *. * : :. : : : : :.: * *::* . . :: : :* .: :*:* : :: .: :*: : : :: *: * ..** ***:.: ::*: . : . .. : : .*...:**:. : : . * . *: * *:. *: .* : : :. . : *:: **.* . :*::: . : : *:. : : : :: *.:. .. . . :. :*. :::. : . : :. : :* * : : :*. :** . :: : : : : . * : * .:* ** : :: : * :. . :. : : : .. *** :: . ::* .:: : : : .: . .. .:: . . :*:: . : : . : : . : : : . :* : : : .: : : . : :: : . : .:. : : : *.: : .* .. .: :: . *. ..**.:*.: . . . ::. *: ::.* :. : : : :.. : : :.:: : . : *. . * : . .. : * . :. : :. . * . : :.. : : . .. . . . :: .. .. : ... . :: . . . .. . . .:: :: .: . . ", "identical_positions": 64, "similar_positions": 311, "identity": "4.57%" }, { "cls_id": "homologset.agr.SGD:S000002734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEF1-1", "uniprot_id": "ASTRA_MOUSE", "id": "Q8VEF1-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR----------------------------------------------------------LQLLPPIRPPPASEPEPG-------TMVEKGSDSSS----------------------------------EKSG----------VSGTLSTQSLGSRNFIRNSKKMQSWYSMLCPTYKQRNEDFRKLFS--KLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLS-------------PRELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLGSP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ISPSGAADHSQEPSPVGSRRGRVTPNLSRASSDADHGAEE-DKEEQTDG-LDASS-----------SQTVTPVAEPLSSEPT---------------------PPDGPTSS--LGPLDLLSREELLTDTSNSSSSTGEEG--------------DLAALLPDLSGRLLINSVFHMGAERLQQMLFSDSP-FLQGFLQQRKFTDVTLSPWSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLDRELAKAEKLSLEEG---------------------------GKDTRGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALN----ALLFYRLWSLER---TAHTFESWHSLALAKGKFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLD-----EMKFSLEKLHQGITVPDPPLDTQPQPDDSFP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR56-1", "uniprot_id": "ASTRA_RAT", "id": "Q3KR56-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSSPSSSPSLRKR----------------------------------------------------------LQLLPPSRPPSAPEPEPG-------TMVEKGSDSSS----------------------------------EKSG----------VSGTLSTQSLGSRNFIRNSKKMQSWYSMLCPTYKQRNEDFRKLFS--KLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLS-------------PRELWHLVHQCYGSELGLTSEDEDYVCP--LQLNGLGSP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ISPSGAADRSQEPSPVGSRCGRVTPNLSRASSDADHGAEE-DKEDQTDSQLDASS-----------SQTVTPVAEPLSAEPA---------------------PPDGPTSN--LGPLDLLSREELLTDTSNSSSSTGEEG--------------DLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSP-FLQGFLQQRKFTDVTLSPWSSDSKCHQR-RVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDRELAKAEKVSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRG-HRD------GPQHPDPDPCTQTSMHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIV----LIVLIALN----ALLFYRLWSLER---TAHTFESWHSLALAKGKFPQTATEWAEILALQKHFHSVEVHKWRQILRASVELLD-----EMKFSLEKLHQGITVPDPPLDTQPHPDDSFP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CP6-1", "uniprot_id": "ASTRA_HUMAN", "id": "Q96CP6-1", "name": "Protein Aster-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFDTTP-------------------HSGRSTPSSSPSLRKR----------------------------------------------------------LQLLPPSRPP--PEPEPG-------TMVEKGSDSSS----------------------------------EKGG----------VPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFS--KLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLS-------------PRELWHLVHQCYGSELGLTSEDEDYVSP--LQLNGLGTP-KEVGDVIALSD------------------------------------------------------------------------------------------------------ITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEE-DKEEQVDSQPDASS-----------SQTVTPVAEPPSTEPT---------------------QPDGPTT---LGPLDLLPSEELLTDTSNSSSSTGEEA--------------DLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSP-FLQGFLQQCKFTDVTLSPWSGDSKCHQR-RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEG---------------------------GKDARGLLSGLRRRKRPLSWRA-HGD------GPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAG--IPSALVL----------------------------------------------------------------------------------------------------------ISIVICVSLIILIALN----VLLFYRLWSLER---TAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLD-----EMKFSLEKLHQGITVSDPPFDTQPRPDDSFS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NZU2-1", "uniprot_id": "A0A8M9NZU2_DANRE", "id": "A0A8M9NZU2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYEGLLVMAMTTPPEILIAEPISIPILNILPPSSDTESWSRSPSPRAHRYRSRSREKRKAKAQQEDKSGAKHCDKRKGELERSPSHASASSSMVCNVDDEEQGNPCVLLLPPSRSWSRSSSLSRRSRWSIRSLLNKDSDCDSSSTASNSPRSTPGSSPSLRRRVLGGRASEGETAGEKSGGGSDSPLPPTPSSSTSSYPLAARHFTRNAKKMQSWYNVLSPTYKQRNEDFRKLFK--KLPDTERLIVDYSCALQKDILLQGRLYLSENWLCFYSNIFRWETTITILLKDVTNLTKEKTAKLIPNAIQISTENEKHFFTSFGARDRSYMMIFRLWQNALMDKTLS-------------PKELWHIVHQCYGTELGLTSEDDDYVSPTAEHMNGLLPG-EEPVSVTDLLD------------------------------------------------------------------------------------------------------LGSVPVAPASSSPPSSASVLPCASGSSPPSSSSSSQPVEVPSIRASIDPEPSPPS-----------SQSSLPPVTNTGAVPASVILKEGGDSQSESANHSLQSPPSIPHNLGNLSSLDMTNDEDLPTDPSNSSD-TQEES--------------EVESFCADLNGRLHINTVVRMGVDKLHDLLFSDTH-FIQHLFSQRHFTDLSVHEWQQDSSSGSSSRVLSYTIAINNPLGPKTAPVVETQTLHKSSSRSECYVVDSEVITSGIPYQDYFYTVHRYCLTSVNKHKSRLRVSSDICYRKQPWSLVKALIEKNTWSGIEEYYRHLEMEVCKLETLLQTEVT------------------VVSAGEMPSPDSTKTPPGLRRRKRTCPRRAGERDRDREAAGGGERGDRITDERDRREAGGQYMKLGERWRAGGGSNNNSISTILLI----------------------------------------------------------------------------------------------------------VSFI----LVVLVALN----MMLFYKLWALER---AAHTLETWHSYSLTDSPLPQSAGEWAQVLQLQRQFHQAQMNKWQQILQSSVTLLD-----QMKQSLEKLHRGMIPPEGQQESDPEPDTLADQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CI52-1", "uniprot_id": "ASTRC_MOUSE", "id": "Q8CI52-1", "name": "Protein Aster-C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGALTAR-----------------------------------------------------------QIVNEGDSSLATELQ----------EEPEESPGPV------------------------------------------------VDENIVSAKKQGQSTHNWSG--DWSFWISSSTYKDRNEEYRQQFT--HLPDSEKLIADYACALQKDILVQGRLYLSEKWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLIIFRLWQNVLLDKSLT-------------RQEFWQLLQQNYGTELGLNAEEMEHL-LSVEENVQPRSPGRSSVDDAGERD------------------------------------------------------------------------------------------------------EKFSKAVSFTQESVSRASETEPLDGNSPKRGL-------GKEDSQSERNVRKSPS-----------LASEK----RISRAPS--------------------------------KSLDLNKNEYLSLD--KSSTSDSVD---------------EENIPEKDLQGRLYINRVFHISAERMFELLFTSSH-FMQRFANSRNIIDVVSTPWTVESGGNQL-RTMTYTIVLSNPLTGKYTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLESYFKKLESDLLMEESVLSQSI-----------------------------EDAGKHSSLRRRRRTLNRTA-------------EPVPKLSSQRSSTDLGFEAKVDVT--GKRKTVDSYDTALIVV-----------------------------------------------------------------------------------------------------------MSIFL----LLLVLLN----VTLFLKLSKIEH---ATQSFYQ---LHLQGEKSLNLVSDRFSRTENIQK-NKDQAHRLKGVLQDSIVMLE-----QLKSSLIMLQKTFDLLNKNKSGVAVES---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A135-1", "uniprot_id": "D4A135_RAT", "id": "D4A135-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTQAVLWRSPSREEP----------------------STPQTNSQCQADS-----------------------------------------------------------PIVNDGDSSLATELQ----------GELEENSSPA------------------------------------------------VDESIVSAKKQGPSTHNWSG--DWSFWISSSTYKDRNEEYRQQFT--HLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLT-------------RQEFWQLLQQNYGTELGLNAEEMEHLSLSIEENVQPRSPGRSSVDDSGERD------------------------------------------------------------------------------------------------------EKFSKAISLTHESVSRASETESLDGNSPERGL-------GKEGSQSERHVRKSPS-----------LASEK----KLGRVPS--------------------------------KTLDLNKNEYLSLD--KSSTSDSVD---------------EENIPEKDLQGRLYINRVFHISAERMFELLFTSSH-FMQRFTNSRNIIDVVSTPWTVESGGDQL-RTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLENYFKQLESDLLMEESVLSQPM-----------------------------EDAGKLSSLRRRRRTLNRTA-------------EPVPKLPSQRSPTDLGFEAKDDIT--GKRKAVDSCDTALIVV-----------------------------------------------------------------------------------------------------------MSVFL----LLLVLLN----VTLFLKLSKIEH---ATQSFYQ---LHLQGEKSLNLVSDRLSRTENIQK-NKDQAHRLKGVLQDSIVMLE-----QLKSSLIMLQKTFDLLNKNKSGVVVES---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYS0-1", "uniprot_id": "ASTRC_HUMAN", "id": "Q8IYS0-1", "name": "Protein Aster-C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGAPTVR-----------------------------------------------------------QVMNEGDSSLATDLQ----------EDVEENPSPT------------------------------------------------VEENNVVVKKQGPNLHNWSG--DWSFWISSSTYKDRNEEYRRQFT--HLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLT-------------RQEFWQLLQQNYGTELGLNAEEMENLSLSIED-VQPRSPGRSSLDDSGERD------------------------------------------------------------------------------------------------------EKLSKSISFTSESISRVSETESFDGNSSKGGL-------GKEESQNEKQTKKSLL-----------PTLEK----KLTRVPS--------------------------------KSLDLNKNEYLSLD--KSSTSDSVD---------------EENVPEKDLHGRLFINRIFHISADRMFELLFTSSR-FMQKFASSRNIIDVVSTPWTAELGGDQL-RTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAI-----------------------------EDPGKLTGLRRRRRTFNRTA-------------ETVPKLSSQHSSGDVGLGAKGDIT--GKKKEMENYNVTLIVV-----------------------------------------------------------------------------------------------------------MSIFV----LLLVLLN----VTLFLKLSKIEH---AAQSFYR---LRLQEEKSLNLASDMVSRAETIQK-NKDQAHRLKGVLRDSIVMLE-----QLKSSLIMLQKTFDLLNKNKTGMAVES---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q853-1", "uniprot_id": "A0A8M9Q853_DANRE", "id": "A0A8M9Q853-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTETP----------------------KPLMGNELAQENG-----------------------------------------------------------QSGEVRGSSEEQEMKGI-------TQTPKQPMGKA------------------------------------------------TDGKNPEEQEALEVTVQFTAAPQSTDSLYYTSYKQRSDEFRKLFK--EVPEHEKLVVDYTCALQKDILLQGRIYFTENCLCFYSHVFR-GTKIMVNMKDIISVSKEKTAKWIPNAIQISTNSEKLFFSSFSTREKSYQSIFRLWQNVLMEKKLT-------------KLELLQMVRQHYGNDLGLSHDEMESFQTSVDTITPTLPSLNMRGEDYTGRP------------------------------------------------------------------------------------------------------ERPTSLRLPHGELNSYEASTPQGDDTQSSVGLHSVLSANGGDDSLSTPSHQLSPN-----------LSLNRSGSERVSKRSS--------------------------------FSLDLNANEDQLSDNSRSDSLEEVE---------------ERETASPVSQGRLFVNRVFHISAEKMFNLLFSDSS-FTRRFMDIRKITGITATPWKKEASGCMK-RTLNYTITINNPLVGKFSTATETQTLYKESREGQYYMIDSEVYTHDVPYHDYFYTQNRYCIIRNSKHKCRLRIYTDVKYKKQPWGLVKSFITKNSWSGLEDYFRHLEAELLDEEAELTQGS-----------------------------GDAGKTGALRRRRRTYSRTL-------------QEHMKPAKAQYSTDSEQQRTGTMGPMDIKNTPHRWNITSVVFG----------------------------------------------------------------------------------------------------------MSLIL----FVLVVLN----LGLFFKLWAMED---VAHRMYLNTKHRMKERVESSLPPDLGPRHGMPHR-SQEEVHLLRAVLQDSINLLE-----QLRSSLLVLQQNFQVYNRTSSPL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "R9PY62-1", "uniprot_id": "R9PY62_DROME", "id": "R9PY62-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKEDIKKPPRKTLNVDAKKAKRKKMIKDSDKINPTTSSVNITVTTAESSSSCKNPANANMIPETTQPDQLQSQTQTQAQLQPQSQSPSQCQQAQENPEHLQQQSQPEEELQAEAPGSNAGDRRDSITEEITITSTTNSSQSTKLLTIQEAAGSFEQSSVSAVSTSSKQIASTTAGGSPPAAAAPGANEFNGSVLRLTQAATSTSPGSISSAGNTATLGAAPSINIVSSESTRDQTQQPQSVDPNGVAAPGDSPSSRKSSTSSKGKASQAKLSTSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTSNEKPAKTSRLSERAKKKSWYNVIYPNYKSRAEDFKKLFK--DVPNDERLIVDYSCALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSGKDKYFFATFTSRDKSFLMLFRVWQNTLMNKQFS-------------PQEIWQHVHTCYGDELGLTTDDEDYIDPTLNKTNEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSGGGVRASAPRKSKTKYFFNSSKSSANASASGSDNNKTRESSRKLNKKMKQNAKELTLSSVKPTELSVSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSGSLSGSNTAAASGSGSDKMSAEKKVSTAS-----------NSAAVAAAEAAQSLASAS--------SGSGSLESKMEMKRKLGKMHRQREEGKNAAESVPTDVSDSSDSEENNLP-----------FVPTTECTSTHEGRQIVHTILPINVDTLFNLLFSKSK-FITDFHAMRKSTDLVLGEWTKNEEGLQV-RTVNVTVQLAASVGPKTSKVTEYQTQRECSKPGELYSIDVNSVNAGIPYAESFSVLIHFCLARTVDDHTMLSIHTQIKYKKSIWGVVKGFIEKNTWAGLEDFFGAQLHALQSETCIPPAKGKGRRPRRGMNQQSATSTSTTSITTGALHTATSTDNDSIQESRHPHQQDQHQHQHLHMHHHHHHHHGSQHHHHDARHSHHHHHQPLLPHHQQQHPHHWHHRKALLQSGRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVGAAAGHPLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGDGQPLASGQGSQGHRLRHKGLWLLVILLLCLMLALN----VILLLKLWRLEERIDVDLNRRARMPSLAALSELPSTNQEWLELLRDQEMAHENELHKWQQVLQTAIELLK-----KVSIVCEKITNDSHLRQSIESMSMAGRTEF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06681-1", "uniprot_id": "YSP2_YEAST", "id": "Q06681-1", "name": "Membrane-anchored lipid-binding protein YSP2", "aln": "MRDEATRKKRSFSDGHFFKKLKLMSRKKQPVMERSKTTRTRKESTNSAAKSSLSLRRANNGRKTIAKRRVLTDIGSTNEGVAGNSGSNSPAQYSHTPHFSDSIPPLPLELPDIVSIRSSRSHISNKSNKNKHGIDLTFIPRRSLQNSKAGLKKPNTSPQGYFNIPVTIDRASEKVKHTDTKNTFNSSSSENERPVLSILQKDDSQSSSHPAIDSMSAPNNINNNNDIENSSNSLFDTILSIAHSAISHVPKISALNTEIQREFSHSGESHTGSTRHPYFHIHHAQQQHPLSQQQGPLPVSENANQNPNDTVLIHSPSANTAHRSSSFLRHLDYLLSPTSGPASDKHTQVEEGDDEEELSPLSKAFLSPSTQLVPTNTSTTPLSGSLTPNNRNVNANSNSETENDNDRDDRSNVGKVKFQPLKVHEPAISTFGKGNLTLEAVAGSSDIDNTTIDLDENNTNNNPNASSTNLSHISKSNVNNNLGPKELNTSYRNSTYIDMARFENSQSNLSSHRARSKTLPANKALENAVGDEGNSKRNSRYSSYSNDMAFDDADERKFRSMSKKFLNRRSFSPSNLGNKVIPG-INLRNSFNKNRNSSSDFFSTNQGQQMPRTSTAGSGNIHAIMGLDSGNDDFKLEGIEYASEKKNSEFHTLFKDCDINPNEKLIVDHSCALSRDILLQGRMYISDAHIGFFSNILGWVSTVFIPFKEIVQIEKKTTAGIFPNGIVIDTLHTKYIFASFMSRDATFDLITDVWNQIILGKKYRNGFGNNDDGTISDSSSAFFDDSDDNDDDGDLDDDDPDINSTDMTSSDDIDADVFNESNDLGKNQKSTNYLLGPNKHSPTTADFKPSNNDHLVIEANINAPLGKVVNLLYG---------------------------------EDVSYYERILKAQKNFEISPIPNNFLTKKIRDYAYTKPLSGSIGPSKTKCLITDTLEHYDLEDYVKVLSITKNPDVPSGNIFSVKTVFLFSWDKNNSTKLTVYNSVDWTGKSWIKSMIEKGTFDGVADTTKIMISEIKKILSDEDSNINSKHQASNNESEEEIINLPTIGPPVHDPTEPDFQKGKDDTVIDEKINIPVPLGTVFSLLYGDDTSYIKKIIENQNNFNVCDIPKFVNN-----AREITYTKKLNNSFGPKQTKCIVTETIEHMDLN-SFFMVKQIVRSPDVPYGSSFSVHTRFFYSWGDHNTTNMKVVTNVVWTGK--SMLKGTIEKGSIDGQRSSTKQLVDDLKKIISNASSTKK----------------------------KSRRRGKTVNKRKSSPSTIKNEKN---------EENFEDTSTKNSFFSAFSMLQQVNITSVQGIMTIISFFICLIFFFRLLFHSKN-----------------------------------------------------------------------------------------------TSNIQIITPGTILINGNEYNYVPNFKTLYHVYEDNIIKDARRKDSNKNNIVTDTEGLIWDWLIDRGNGTVQNSVLSNHIKESNNKKVKLVNGVSDHKIQQLVESIKITELQLQEMKELLAQTDNTSATNQLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :.: .::: *. .: *:*:.*::***.::**:***:*.:: : *.:::: : : : *:: : *:.** :**.* * : * :*::* :*: : : :*:: :: * . . : .* :: : . . . . . : . . *. : : . : : .:*: . : : : .: : * :. * : . * : :* . . :. . .:** . * . :: . : : ::: : . .::*. * *.: . .. : :.. : . . :. . ::: * : * : : . : : . : ::. :: : : ", "identical_positions": 43, "similar_positions": 148, "identity": "2.67%" }, { "cls_id": "homologset.agr.SGD:S000002736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PEC4-1", "uniprot_id": "SKP1_RAT", "id": "Q6PEC4-1", "name": "S-phase kinase-associated protein 1", "aln": "--MPTIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGM------------------------------DDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDP-PPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTX5-1", "uniprot_id": "SKP1_MOUSE", "id": "Q9WTX5-1", "name": "S-phase kinase-associated protein 1", "aln": "--MPTIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGM------------------------------DDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDP-PPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63208-1", "uniprot_id": "SKP1_HUMAN", "id": "P63208-1", "name": "S-phase kinase-associated protein 1", "aln": "--MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGM------------------------------DDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDP-PPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77430-1", "uniprot_id": "O77430_DROME", "id": "O77430-1", "name": "", "aln": "--MPSIKLQSSDEEIFDTDIQIAKCSGTIKTMLEDCGM------------------------------EDD-ENAIVPLPNVNSTILRKVLTWAHYHKDDP-QPTEDDESKEKRTDDIISWDADFLKVDQGTLFELILAANYLDIKGLLELTCKTVANMIKGKTPEEIRKTFNIKKDFSPAEEEQVRKENEWCEEK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KJ69-1", "uniprot_id": "Q7KJ69_DROME", "id": "Q7KJ69-1", "name": "", "aln": "--MPIIRLESADKEIFDTDQEIAKCSETIRIAIEDLG--------------------------------DESDNSVLPLPNVNSLILKKVLHWATYHKDDP-VVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGKSPQAIRDTFAIQNDFLPQEEEQVRKENEWCEDK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1Q0-1", "uniprot_id": "Q9W1Q0_DROME", "id": "Q9W1Q0-1", "name": "", "aln": "--MPVIKLQSSDGEIFETDIETAKCSSTIKTLLEDCPV------------------------------EAE-NDTLIPLPNVNSTILKKVLIWAKHHREDI-AEENEEEAAKSVAVQITPWDAEFLSMDQGTLFELILAANYLDIPNLLNAACMTVANMIKGRTTEEIRQTFHITNDFSPSEEDLMTMESEVPQEDEAIEYGEII", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52286-1", "uniprot_id": "SKP1_YEAST", "id": "P52286-1", "name": "Suppressor of kinetochore protein 1", "aln": "MVTSNVVLVSGEGERFTVDKKIAERSLLLKNYLNDMHDSNLQNNSDSESDSDSETNHKSKDNNNGDDDDEDDDEIVMPVPNVRSSVLQKVIEWAEHHRDSN-FPDEDDDDSRK-SAPVDSWDREFLKVDQEMLYEIILAANYLNIKPLLDAGCKVVAEMIRGRSPEEIRRTFNIVNDFTPEEEAAIRRENEWAEDR---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VWC5-1", "uniprot_id": "Q9VWC5_DROME", "id": "Q9VWC5-1", "name": "", "aln": "MDAPTIKLESSDGVIFSTEVKAAKLSETIKTMLEVSAV-------------------------------ENDENAVVPLPKVNAFILNKILTWAYHHKDDDDQAAEGEELTPQSPHDISPWDANFINVDQPILFEITVAANYLEIKGLEDLCCKTLANMIRGKTPEEIRQTFNIEDDL-PIDTAELG-EDL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWC4-1", "uniprot_id": "Q9VWC4_DROME", "id": "Q9VWC4-1", "name": "", "aln": "MDAPTIKLESSDGMIFSTEVRAAKLSETIKTMLEVSAV-------------------------------ENDENAIVPLPKVNAFILSKILTWIYHHKDDDAHGAEGVELSPQSPHDISAWDANFINVDQPTLFEIILAANYLEIKGLVDLCCKTVANMIRGKTPEEIRHTFNIPDEI-PSRTAQLG-EDL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWC3-1", "uniprot_id": "Q9VWC3_DROME", "id": "Q9VWC3-1", "name": "", "aln": "MVTPTIKLESSEGVIFPTEVRVAMVSETIKTMLDHFAV-------------------------------QNDENAIVPLHSVSTFTLGKILAWANHHKDDDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGKTPEEIRFIFNIPEDVSPSVDGELRWKDLFLWPMDF-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *.: * .: . * * :: :: : :: :*: .* : * *:: * :*::. : : . : ** *: ::. * *: :**: *:* * : .:*:**:*::.: ** * * .:. : :. ", "identical_positions": 29, "similar_positions": 51, "identity": "14.15%" }, { "cls_id": "homologset.agr.SGD:S000002737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJK4-1", "uniprot_id": "PEX3_RAT", "id": "Q9JJK4-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSMWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKLREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKNRP-----------------SNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NATVGKNGTSILAPPDVQQQYLSSIQHLLGDG-LTELVTVIKQAVQRILGSISLKHSLSLLDLEQKLKEIRTLVEQHRS-CWNDKDASKSSLCHYMMPD---------EETPLAAQAYGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSINSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXY9-1", "uniprot_id": "PEX3_MOUSE", "id": "Q9QXY9-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSMWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKSRP-----------------SNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NATVGKNGTTVLAPPDVQQQYLSSIQHLLGDG-LTELVTVIKQAVQRILGSVSLKHSLSLLDLEQKLKEIRILVEQHQS-SWNDKDVSRSSLCQYMMPD---------EETPLAAQAYGLSHRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSINSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56589-1", "uniprot_id": "PEX3_HUMAN", "id": "P56589-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLRSVWNFLKRHKKKCIFLGTVLGGVYILG----KYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQ-QLNSESLTALLKNRP-----------------SNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYIYLD--------------------------------------NAAVGKNGTTILAPPDVQQQYLSSIQHLLGDG-LTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPD---------EETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHG-------------------------------NSMNSLSSVSLPLAKIIPIVNGQIHSVCSET------PSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUL8-1", "uniprot_id": "Q9VUL8_DROME", "id": "Q9VUL8-1", "name": "Peroxisomal biogenesis factor 3", "aln": "--MLSRLQDFLSRHRRKFIVTGVLVGGTIFAA----RYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTCNQVILGMGEEMCQAVLR-ECSTDELLEQLRQNP-----------------KNKLELWEDMKIVAFTRLATYVYASSMLVIALRVQLNLLGGYIYRD--------------------------------------IMTEQKQ-----VTDELKQQYLSLIRHFITDSGIRDLARYIRTQVIAVTKTIPLSEQLSLSDLEQLFWSLQMAINADTR------RDPNSRMSKYLLPS---------QNP----------SHSPLLQKMVNETLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQHLPQAKVQTQQEQSVKFNQAGSLGASTSKSQNGLENNNLLNINRVLLALAKLIPIISGLTSRGFDTTSRPHNLPTQLLTFYVVAEKTKTLGANVYESFSSA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28795-1", "uniprot_id": "PEX3_YEAST", "id": "P28795-1", "name": "Peroxisomal biogenesis factor 3", "aln": "MAPNQRSRSLLQRHRGKVLISLTGIAALFTTGSVVVFFVKRWLYKQQLRITEQHFIKEQIKRRFEQTQEDSLYTIYELLPVWRMVLNENDLNLDSIVTQLKDQKNQLTRAKSSESRESSPLKSKAELWNELELKSLIKLVTVTYTVSSLILLTRLQLNILTRNEYLDSAIKLTMQQENCNKLQNRFYNWVTSWWSDPEDKADDAMVMAAKKSKKEGQEVYINEQAFLSLSWWILNKG-WLSYNEIITNQIEIEFDGIHPRDTLTLEEFSSRLTNIFRNTNSQIF------QQNNNNLTSILLPKDSSGQEFLLSQTLDADALTSFHSNTLVFNQLVNELTQCIESTATSIVLESLINESFHFIMNKVGIKTIAKKKPGQED-------------------------------QQQYQMAVFAMSMKDCCQEMLQTTAGSSHSG-----SVNEYLATLDSVQPLDDLSASVYSNFGVSSSFSFKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.**: * :. . :.. . : :: : : * : : :.: : : :**..:. . .: : .: . : . :.: *:.. ..* *:*::::: :: : . .*: . *:: *:***:: * * : *. :* :** :: .. . * : : . *:* ::.. : .: : . . : ::*. .:. . :::** : :** * . :...* : :. . : . :. .: . :.: . : .. : : . :.*.**. *. . ", "identical_positions": 37, "similar_positions": 131, "identity": "7.64%" }, { "cls_id": "homologset.agr.SGD:S000002738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94888-1", "uniprot_id": "UBXN7_HUMAN", "id": "O94888-1", "name": "UBX domain-containing protein 7", "aln": "MAAHGGSAASSALKGLIQQFTTITGASES-VGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSTVRPHT---------------------------EEEVRAPIPQKQEILVE-----------------------------PEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQ------------ELRNGGAIDK------------KLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLG---DFPYVSILDPRTGQKLVEWHQLDVS--SFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5G6-1", "uniprot_id": "UBXN7_MOUSE", "id": "Q6P5G6-1", "name": "UBX domain-containing protein 7", "aln": "MAAHGGSAASSALKGLIQQFTAITGASES-VGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSTVRPHT---------------------------EEEVRAPIPQKQEILVE-----------------------------PEPLFG----------------------VRQEQ------------ELRNGGAIDK------------KLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLG---DFPYVSILDPRTGQKLVEWHQLDVS--SFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSAQAKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPLTEPPARTEPGTATNHQGLPSMDSEVLEMSPEKSDGIVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06682-1", "uniprot_id": "UBX5_YEAST", "id": "Q06682-1", "name": "UBX domain-containing protein 5", "aln": "-----------MSEGKVDEFMAITGADDAAIATQFIEMADGNLNTAISLFFENGGAALLSSNNTPTPSNSTPMAPTSVDSDADAQLAERLQREAYQQQQPDQDYVRPPDEARHEVLTETSGFPISYGGIGGRFEPLHRVNDMFDEGRPESIFNQRLDDTNTNTYINDNSSDSLDSEEENDDDEYEYVEEPVIELDEDGNIKEYTKLVRKPKTISKEQKLALLFRPPFSIMSKLDLDAAKQKARAKQKWIMINIQDSGIFQCQALNRDLWSSRPVKTIIKENFVFLQYQYESRNAQPYLQFYHLNNKDDLPHIAILDPITGERVKQWNRVVPIPEQFISEINEFLASFSLDPKVPNPTVNEPLPKVDPTTLTEEQQMELAIKESLNNNSSKSNQEEVPSTGEEQ----------------------------------------KRVQEPDPFSTIEARVHP-------------------EPPNKPGITTRIQIRTGDGSRLVRRFN------ALEDTVRTIYEVIKTEMDGFADSRFTLNDHQREDLIDKLN--MTIADAGLKNSSLLLEKLDPEIE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :::* :****.:: :..:::* .:.**: *:::*::.** * .*..:.: *. * : :: **.* ::*:*.* **.:*. .::: ** :.* *.: * .** *****:.:* * .:::**: .: ::**:*****: * **.****:**...**.**:*:*:* * ::*.:.* *:***:*. *:*:::**** **::: :*::: .*:.::. **.... :.... :: . . :*:.*:* **: **::. .* * : * .:*: :: :: *:: .*..* * : *:. *::. ... ::* : :* : .: : * :.: .*:.:.** * : . :.:*: :*: :*** .. :: : ", "identical_positions": 114, "similar_positions": 173, "identity": "19.72%" }, { "cls_id": "homologset.agr.SGD:S000002739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXY9-1", "uniprot_id": "GPI8_MOUSE", "id": "Q9CXY9-1", "name": "GPI-anchor transamidase", "aln": "MAAPCFLTLRVATLAALALLSLGSSAAGH---IEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNARNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRVPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVR------------------KVEITTEKISLQ-WDSQVVDSSSKEDGTAEERMGPLKYAEQLPVAQIIHQKPK--PRDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92643-1", "uniprot_id": "GPI8_HUMAN", "id": "Q92643-1", "name": "GPI-anchor transamidase", "aln": "MAVTDSLSRAATVLATVLLLSFGSVAASH---IEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVR------------------KVEITTETIKLQ-QDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPK--LKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T4E1-1", "uniprot_id": "GPI8_DROME", "id": "Q8T4E1-1", "name": "Putative GPI-anchor transamidase", "aln": "--MFNIMLVKFVVIFALILASCRVEADNTSVLPEGFVDAAQRSTHTNNWAVLVDASRFWFNYRHVANVLSIYRSVKRLGIPDSQIILMIADDMACNARNPRPGQVYNNANQHINVYGDDVEVDYRGYEVTVENFVRLLTGRTQNGTARSKKLLSDAGSNVLIYLTGHGGDGFLKFQDSEEITSQELADGIQQMWEKKRYNELFFMVDTCQAASLYEKFTSPNVLAVASSLVGEDSLSHHVDPSIGVYMIDRYTYYALEFLEKVQPFSKRTIGEFLQVCPKRVCISTVGVRKDLYPRDPHKVPITDFFGAIR------------------PTRVSTDRINVT-LAN--------ED-------------------DFIFDKDK--MVTKKP---FKIVMESQFPSELFK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49018-1", "uniprot_id": "GPI8_YEAST", "id": "P49018-1", "name": "GPI-anchor transamidase", "aln": "MRIAMHLPLLLLYIFLLPLSGANNTDAAH----------EVIATNTNNWAVLVSTSRFWFNYRHMANVLSMYRTVKRLGIPDSQIILMLSDDVACNSRNLFPGSVFNNKDHAIDLYGDSVEVDYRGYEVTVENFIRLLTDRWTEDHPKSKRLLTDENSNIFIYMTGHGGDDFLKFQDAEEIASEDIADAFQQMYEKKRYNEIFFMIDTCQANTMYSKFYSPNILAVGSSEMDESSYSHHSDVEIGVAVIDRFTYYCLDFLEQIDKNSTLTLQDLFDSFTFEKIHSHVGVRTDLFDRNPSEVLITDFFANVQNVIPDDSKPLSVSHYHHYKDHIDTAQYELNNNVLDLALETYRKNNQSSKIEKKIKDIKSTSVLDVDIDSNECFFTSFKQSATIILALIVTILWFMLRGNTAKATYDLYTN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * . : :******** :*********:**.**:**:*********:*:**::**:***.** *. *:.: : :::***.******.********:*:**.* . .:**:**:* **::**:*****:.******:***:. ::**.::**::*:****::*::****. ::*.:* ***::*:.** :.*.* **: * *** ::**:*:* *:***::: * .: :::: . * * *.**: *:* :* *****. :: .: * .: :: :. :. : : : : : : ::: ", "identical_positions": 142, "similar_positions": 109, "identity": "33.73%" }, { "cls_id": "homologset.agr.SGD:S000002741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ASZ5-1", "uniprot_id": "TCF25_RAT", "id": "A0A8I6ASZ5-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKTG------LGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDSASSGNK--GRAKHGNPENKQDGDAAAKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILER----------IEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAVLGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFE--HSEEYQQAQHKFLVAVESMEPNNIVALLQTS--PYHVDSLLQLSDACRFQEDQEMARDLIG------EPAYPHLLPMEKSWC----RRP-HWSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHMALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPDHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLEAVDSGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQS-VMGFDPLPPVDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3L2-1", "uniprot_id": "TCF25_MOUSE", "id": "Q8R3L2-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPDALKFVLLDDDDAEEEGPKPG------LGGRRPGGAGKEGVRVNNRFELINTEDLEDDLVVNGERSDCTLPDSVSSGNK--GRAKHGNAETKQDG-GATKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILER----------IEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAVLGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFD--HNEEYQQAQHKFLVAVESMEPNNIVVLLQTS--PYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLTLYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALGQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLQAVDAGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQS-VMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ70-1", "uniprot_id": "TCF25_HUMAN", "id": "Q9BQ70-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRE------LGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVAPGNK--GRGQRGNTESKTDG-DDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILER----------IEDSTGLNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAILGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFE--HSEEYQQAQHKFLVAVESMEPNNIVVLLQTS--PYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQS-VMGFDPLPPSDTIYSYVRPERLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMANFHLNDLEAPHEDDAEGEGEWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05468-1", "uniprot_id": "RQC1_YEAST", "id": "Q05468-1", "name": "Ribosome quality control complex subunit 1", "aln": "MSSRALRRLQDDNALLESLLSNSNANKMTSGKSTAGNIQKRENIFSMMNNVRDSDNSTDEGQMSEQDEEAAAAGERDTQSNGQPKRITLASKSSRRKKNKKAKRKQKNHTAEAAKDKGSDDDDDDEEFDKIIQQFKKTDILKYGKTKNDDTNEEGFFTASEPEEASSQPWKSFLSLESDPGFTKFPISCLRHSCKFFQNDFKKLDPHTEFKLLFDDISPESLEDIDSMTSTPVSPQQLKQIQRLKRLIRNWGGKDHRLAPNGPGMHPQHLKFTKIRDDWIPTQRGELSMKLLSSDDLLDWQLWERPLDWKDVIQNDVSQWQKFISFYKFEPLNSDLSKKSMMDFYLSVIVHPDHEALINLISSKFPYHVPGLLQVALIFIRQGDRSNTNGLLQRALFVFDRALKANIIFDSLNCQLPYIYFFNRQFYLAIFRYIQSLAQRGVIGTASEWTKVLWSLSPLEDPLGCRYFLDHYFLLNNDYQYIIELSNSPLMN-CYKQWNTLGFSLAVVLSFLRIN------EMSSARN----ALLKAFKHHP------LQLSELFKEKLLGDHALT-KDLSIDGHSAENLELKAYMARFPLLWNRNEEVTFLHDEMSSILQDYHRGNVTIDSNDGQDHNNINNLQSPFFIAGIPINLLRFAILSEESSVMAAIPSFIWSDNEVYEFDVLPP--------MPTSKESIEVVENIKTFIN-------------EKDLAVLQAERMQDEDLLNQIRQISLQQYIHENEESNENEG-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******:.:: *.* ..: : ....: : * . * ...: .** :: * : : : : :* : .: ** * ::.:. .. . .*: . : **.. * *: ..::.*:*: .. * :*...*:.: . * :.: :.::*:*.**:* *. .: : ** :: * ::*: :*. :. * .: ***:**.* :* :**: *: :.: ::: .* ::* :: : * :* **** .***:: * *:. :..*: : * : : . * : .***:::: :. * :** ** *: *:: **.* **** ::** * .:*:*:*.* :. : .* .:.**:.:. :* : * ****: : :*:. .* *: ..: : :..* : : .*. .* . :. *:.* :**:. :::*.::: .:*: . *: :::: :.: : .: * *: *..**** ...:**:*. : ::. * ** *** * ..:. :.* *:. *:.:* .. : *: :*:: : :::: * ..*:: ", "identical_positions": 139, "similar_positions": 242, "identity": "18.08%" }, { "cls_id": "homologset.agr.SGD:S000002742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYJ1-1", "uniprot_id": "A0A8I5ZYJ1_RAT", "id": "A0A8I5ZYJ1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSPAHPQLPILQTQMVSDGMTGSNPVSPASSSSPASS---------GAGGISPQHIAQDSSLDG-----------PPGP-----QDGTTVPLEGFSLS--HAADPINRG----------------------------------------------------------------------------------------------------------------------------------------------PKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLASSKAGSSPCLGSSSAASSPPPPVSRLDDEDGDFQPQEEEEEDDEETIEVEEQQEGNDAETQRREIELLRHEGELPLEELLRSLPPQLLGGPFSPSQTP-SHDSDTPDGPEENIEEEPSQDLEVDPPSSSVTQCNKQCWHPDEDDEEFTANEDEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAYDASAPGSGNSEDEEEVEANSSDCELEETRDVEEAAQEDSSSQSDSAEEHSEDEEDEHSEEE-MSGSSQSEESESDESEDAQSQSQADEEQEDEG------DDDDDDFGVEYLLARDDERSEVDGGSGPPTPGPTTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATEVHPLQQIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRILLEIATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNSPRAPLGPVPVRPPPGPEVSTQPTLGPVPPVLPTPLMVSASPAGTPVVPASRPPGPVLLSPLQPNTGPLPQVLPSPMGVMSGTSRPPTPTLSLKPAPPAPVRLSPAPPPGSSSLLKPLTVPPGYTLSPVAATTTSSTIATVTTTAVPAPNSTPQRLILSPEMQARLPSGEVVSIGQLASLAQRPVTSAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP-STPSTTPAPTGLSLPLAANQVPPSMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPSSSGLPAVLTPRPTLTPSRLTSPTLGTTRTPIPTPTLVRPLLKLVHSPSPEVSASAPGAAPMTISSSLHMPSSLPGPASSSMTIHNSSPLSSPVVSSTVSVPVSSSLPISVPTTLPVPASAPLTIPITAPLPVSDLGPALLTGVTPALA-VVSAASGPP-LASAGVSPSVSALALGLATTPALSPPQTSGHSLLLATTSSHVPGLNSAVAPACSPVLVPASALTSPFPISPSSAPAQASLLAPAPSTSQALATSLAPMAASQTTILGPSPTPPLAPLPVLAAS----------QTPLPAMTPPSMSGAPLPSSTLVSAPTSVLAPSSTQTLVSTPVSSPLSSLASTQTLTLAPTLAPTLGGLSPSQTHSLGTGSPQGPFPIQTLSLTPASSLVPTPAQTLSLAPGGPVGPTQTLSLA------PSSPVGPAPAHTLTLAPAASSASLLVPTSVQTLTLSPAPVPVPTLDPSATQTLALAPALTQAPASQASSLVS-ASGAASLPVTMVNRLPVPKDEPETLTLRSGPPSPLPTATSFSGPRPRRQPPPPPRSPFYLDSLEEKRKQQRSERLERIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPIFWTYTEAAHQ--------------AVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPHQAAFQEQLACELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPPGSSVSSV--------------PEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENEGFPAGEGEEASRPGPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDEMSCATSGVSHRRSKKVKAPERLGTRVSERLRGARAETQGANHTP---------VTSSHQTCNTFVPPRCSPVRERIPR-----PRPAPPPAPPAPPPAASPAPAPAPAPPAPPPPVLPPVLPPVPPPPPAPSPPAPSPAPPPPAPAASVASAPASAITSSLATAPIP-------------------ISAPNPVTILPVHILPSPAPLLQLPPCSSPASTPP----------------------------------------------------------------------------SACTPLPTCTPLPAQTSLLTSSSPAPLDS--LPVPISPGVTN--------------------------LLLDSG-EVEVCTQELAP---------------VESLELPGMTNSEASLVS-------LVPPNDLLPVAVDVLPESEKNLPLIP-----APSSTLEAESIPDDQEQEVPGSVEGTNRTLLPGGGELTVSLSESNGLELP----------PSAASDEPL-QLLETHRNLED------TREVQTPVSNSEKPQELVRAEVTAPSTSSSATSSPEGPLPARPPRRRTSADVEIRGQGS------------------------GRTGQPPGPKVLRKLPGRLVTVVEEKELVKRRR-HRATASTLVPG------------------------------VSEVSASPRSPSIHSMSGPESS-----PPSSGPCEAAPTSSLSTPTQHTFIACRHNELG----ITGGGSPENGEGAKLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPS---------SISKGKTNGVDPIPGPETVTATAAEPDLK--------------------------PQPLAPQPVHK----PEPIILSPVEKRRRGRPPKARDLPIPGTISSPGDGNLESRTQPLPFPATLT---------------PLLACPTA-VANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--HPVLDPDSSSVLESCGLGVQRQPLGQAESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSEGSMVMAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPSGLELTPPVVSLTPKFRSTRLRPGSLVPPLETEKMPRKRSGAPVG--------------SSGMAKRGRLQPPSPLGPEGSVEESE---------------------AEASGDEEEGDGTPRRRTGPRR------------------LVGTTNQGDQRILR---SSAPPHLSIPTISHRG-----RKAKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WQ44-1", "uniprot_id": "A0A087WQ44_MOUSE", "id": "A0A087WQ44-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSTAHPQLPILQTQMVSDGMTGSNPVSPASSSSPDSS---------GAGGISPQHIAQDSSLDG-----------PPGP-----QDGTTVPLEGFSLS--HAADLVNRG----------------------------------------------------------------------------------------------------------------------------------------------QKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPPASSKAGSSPCLGSSSAASSPPPPVSRLDDEDGDFQPQEEEEEDDEETIEVEEQQEGNDAETQRREIELLRHEGELPLEELLRSLPPQLLGGPFSPSQTP-SHDSDTQDGPEENIEEEPSQDLEVHPPSSAVTQCNKQRWHPDEDDEEFTANEDEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYACDASAPASGDSEDEDEVEANSSDGELEET--VEEAAQEDSSSQSDSAEECSEDEEDEHSEEE-MSGSSQSEESESDESEDAQSQSQADEEQDDEGEDDDVDDDDDDGFGVEYLLARDDERSEVDGGSGPPTPGPTTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATEVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSHRILLEIATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNSPRPPLGPVPVRPPPGPEVSAQPALGPVPPVLPAPLMVSASPAGTPVVPASRPPGPVLLSPLQPNTGPLPQVLPSPVGVMSGTSRPPTPTLSLKPAPPAPVRLSPAPPPGSSSLLKPLTVPPGYTLSPVAATTTSSTIATVTTTAVPAPNSTPQRLILSPEMQARLPSGEVVSIGQLASLAQRPVTSAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALVQAVAPTPGPTPVSVLP-STPSTTPAPTGLSLPLAANQVPPSMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPSSSGLPAVLTSRPTLTPSRLSSPTLGTTRTPIPTPTLVRPLLKLVHSPSPEVSASAPGAAPMTISSSLHMPSSLPGPASSPMTIHNSSPLSSP-VSSTVSVPVSSSLPISVPTTLPVPTSAPLPIPITAPLPVSDLGPALLTSVTPALA-VVSAASGPP-LASAGVSPSMSALALGLATTPALSPPQTSGHSLLLATTSSHVPGLNSAVAPACSPVLVSASALTSPFPVSPSSAPAQASLLAAAPSTSQALATSLAPMAASQTAILGPSPTPPLAPLPVLAAS----------QTPLPAMTPPSMSGTPLPSSSLVSAPTSVLAPSSTQTLVSTPVSSPLSSLASTQTLTLAPTLAPTLGGLSPSQTHSLGTGSPQGPFPIQTLSLTPASSLVPTPAQTLSLAPGGPVGPTQTLSLAPVPPLPPSSPVGPAPGHTLTLAPAASSASLLVPTSVQTLTLSPAPVPVPTLDLSATQTLALAPALTQAPASQASSLVS-ASGAASLPVTMVNRLPVPKDEPETLTLRSGPPSPLPTATSFSGPRPRRQPPPPPRSPFYLDSLEEKRKQQRSERLDRIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPIFWTYTEAARR--------------AVLFPQQRLEQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPHQAAFQEQLACELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPPGSSVSSV--------------PEDEEEAVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEANRPGPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPHEEEEGPGAGDEMSCGSSGASHRRSKKIRAPERLGTRVSERLRGARAETQGANHTP---------VTSSHHTCNTFVPPQCSPVRERIPRPV---PRPRPPPPPPAPPPPPAPPASPSPAPPPPPAPASP------APPAPPASPPAASPSPAPLPPAASVASA----ITSALATAPIP-------------------ISAPNPVTILPVHILPTP-PLLQLPPSSSPASTPP----------------------------------------------------------------------------SACTPLPTCTPLQAQTSVLTSSSPAPLDS--LSVPISPGVTN--------------------------LPLDSG-EVGLCAQELAP---------------VESLELPGMTNSEASLAS-------LVSPKDLLPVAVDILPESEKTLPCIP-----APSSTLEAESIPNGQQQEVPGPVEGTNTTLLPGSEELTMSLNESNGLELP----------PSAASAEPLDELLETHRNSGE------TREVQIPISNSEKPQELVRAEVTAPSTSSSATSSPEGPLPARPPRRRTSADVEIRGQGS------------------------GRTGQLPGPKVLRKLPGRLVTVVEEKELVKRRR-HRAPASTLVPG------------------------------VSEVSASPRSPSIHSMSGPESS-----PPSSGPCEAAPTSSLSTPTQSTFIACRHNELG----TTTGGSPENGEGTELAITPPAVKRRRGRPPKKNRSPADAGRGVDEVPS---------SISKGKTNGVDPVPGPE--TVTVAEPDLRPQ--------------------FVPGPQPPGPQPVHR----PEPTILSPVEKRRRGRPPKARDLPIPGTISSPGGGNLESRTQSLPFPAPLT---------------PLLACPTA-VTNTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--HPVLDPDSSSILESCGLGVQRQPLGQAESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSEGSMVMAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPSGLELTPPVVSLTPKFRSTRLRPGSLVPPLETEKMPRKRSGAPVG--------------SSGMAKRGRLQPPSPLGPEGSVEESE---------------------VEASGDEEEGDGTPRRRTGPRR------------------LVGTTNQGDQRILR---SSAPPHLCIPTISHRG-----RKAKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRS2-1", "uniprot_id": "SRCAP_HUMAN", "id": "Q6ZRS2-1", "name": "Chromatin remodeling protein SRCAP", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSPAHPQLPVLQTQMVSDGMTGSNPVSPASSSSPASS---------GAGGISPQHIAQDSSLDG-----------PPGP-----PDGATVPLEGFSLS--QAADLANKG----------------------------------------------------------------------------------------------------------------------------------------------PKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGS---GSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEE------------EEDDDFGVEYLLARDEEQSEADAGSGPPTPGP-TTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATDVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASP-VSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLS--PAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPTFWTYTEAAHR--------------AVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPRQAAFQEQLASELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPSSSSVPSA--------------PEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEAGRPG--AEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTP---------VISAHQTRSTTTPPRCSPARERVPRPA---PRPRPTP----------------------------------------ASAPAAIPALVPVP-----------------VSAPVP-------------------ISAPNPITILPVHILPSPPPPSQIPPCSSPACTPP----------------------------------------------------------------------------PACTPPPAHTPPPAQTCLVTPSSPLLLGP--PSVPISASVTN--------------------------LPLGLRPEAELCAQALAS---------------PESLELASVASSETSSLS-------LVPPKDLLPVAVEILPVSEKNLSLTPS----APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELP----------PSAASDEPLQEPLEADRTSEE------LTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGT------------------------GRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPG------------------------------VSETSASPGSPSVRSMSGPESS-----PPIGGPCEAAPSSSLPTPPQQPFIARRHIELG----VTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPS---------STLKGKTNGADPVPGPE--TLIVADPVLEPQ--------------------LIPGPQPLGPQPVHR----PNP-LLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLP------------PLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--LPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSGGSMVVAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGG-------------SPGLAKRGRLQPPSPLGPEGSVEESE---------------------AEASGEEEEGDGTPRRRPGPRR------------------LVGTTNQGDQRILR---SSAPPSLAGPAVSHRG-----RKAKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B358-1", "uniprot_id": "A0A8M2B358_DANRE", "id": "A0A8M2B358-1", "name": "", "aln": "MAEGSSTDHCQDWSQHHGDTGGVSAPFQTAKGPLPPETIKLDYKNVSGKDTSGESPSAPKTEVTPSVKGAVKSTDKDMEHPKPTPLFETNQTAASSVLQKQSTTNSATQLCKFDSKETMEDVTRDLLKTSKEDDISETLSAGGTKQGISGNSICSGYSSKQGGQHITPNRGNNTPNDSDKGSCYLTETCSQTQTSTQKTSTLPKTPGIPTLVENIQCVQELSSQYLHINPKMVTLSKETSTRGDLYCNVAAKEVLCNVSVDEPKLSGHGTCTDTAHVSIMSERSQVMGCGSSDVILKQNDSANQIEISMSSNHQQDGSILLTHAENCVTSEGLESDQPNLSDCLVQQLQESIPTDHKLSQIQICLNNTPDIVNEEERQEMNAEALSAVEVKDLIDVGILMQPDMEDTWLVVSEIDGQPEHGEMEVSDESLVQCPESQSTVAVYECTVPCFTSAAIHSDVKLLLTDKEEEPMETLTQDLQVQSNLGSHPATLKSTKELTIMSSAQKEVAAIVKQNNDSSPTLAKTMTGLTSTLLDVTLDSVHDQQESVVVENTPGVSLISLGTIDPKLLILKKDDRPALKQPSSLSARVATKQNSSILDRSPSNESNKVSECLAKTDTAASSNLKDVKLPADHPVSNTLSQSWTVSTSNVLSQNSSEKEKLYQSSSSGKMLQKESSADTSLSTSVKLHNSESHLTPSPGGVWGPVSDIVPLENQSLDGKPLQDLMSLGGALVLEQQQLPDKLLSTAQDSQHTILEPLDASVEESSDGEADSSLEVQNEDSNAVTNPAENKRGQSRTDRQDLLLKVCQWIAGKVTAASTPSTSPVPCSSPSPSSSDWIRSHTGRTSPIRNSNGKNMPSTSSQGSQSEQTTTPKSTPKHTDLAELAKHEAEIEHRTLALKREGFWSLKRLSRITEPVRPKDHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVMRHHEELRQKEERAKREEQAKLRRVASSIAKEVRAFWSSVEKVVQYKQQSRLEEKRKKALDLQLDFIVGQTERYSDLLSQSLQG---------APVQSSDTAAASKQSQPNPVDEDDRDFEPP-CEEEDDEETIEVEEQQEGNDAETQKREIELLREESTLPLDQLLSTLT--------------------LPQDVESEEEESDTSSLTVE-----------------DEDKEFSANEEDAEDEEETIEAQEVIEGEGDHTEELDDLAREGEMSMEELLEKYRGAYASDFEEPSASADSSE---ESEGTEVEAEEETEGEDSAD-DSGSSSDSQAAVDTEEEDEHEDVQ--------------ESDD----------------------EDDGGEGMEVLLREGDQ-----------SPSVPTSPRPKKEISHIAATAESLQPKGYTLATTKVKTPIPFLLHGTLREYQHIGLDWLVTMNEKKLNGILADEMGLGKTIQTIALLAHLACVKGNWGPHLIIVPTSVMLNWEMELKRWCPGFKILTYYGSQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKSWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRIKADVEKQMPKKYEHVVRCRLSKRQRFLYDDFMAQASTRETLASGHFMSVINILMQLRKVCNHPNLFDPRPIQSPFITKDIIYSTASLVQQALETSPFERCDLSMFDLVGLEHRVSRYQADVFLPQRKVTHQLIQEIMESPDPPPRPKPVRMKVNRMLQPLPKTDGR--SAANSPR------PACPPTTTTIQT-----------PKPLITEVTTSQAPSQPATQ------VCPVTPVTALRAPLAPSTIPSAPAVRPPAPQSVTVRPSAPSTITAAPPPQPQ----------PP------------------------QPSSIMTQRVLLSPDMQARLPSGEVVSIAQLASLAGRPVSSSQGSKPVTFQLQGNKLTLSGTPLHQVPVPQPRPIQGNVMHLVSSSGQHHLISQPAQVAVLHTVSQS---VSSSANP-HPASTTPTCSGLAVPFTTAQVATSMVGGPGIVKIVVRQAPSKEGGSIPTLAVPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPRPAPPQSVTLHPHGSPSPVLRAPTASQLPQRPPVYAAPPR----------------------------------------------------------------------TVASSQTPPARPVLRVLQG---------------------------------------------------------------PPPPPAPEP-----------------------------------------------------------------------PVTKANTPCEDSNEVITLRMSTPKPTSSSQSSSSASHRPRIQPPAPPRSPFYMSWLADTRKAQRDDRISQIMRINELHCTAKPVYGREVLDFLTFLPGPCPSPARPVVNNWSYSGYSSCLIAQSQHTSNILERNTFLREEIHNSEERLRLLSDVIDRFVFVIPPVEARPVTMHSCHPPPSLRHQQAVFSSDLSSYVSPLTHTLHRIQSNMRTYFPDLRLIQYDSGKLQTLHLLLRRLKAEGHRVLIFTQMTRMLDVLEQFLNYHGHIYLRLDGSTRVEQRQALMDRFNADRRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAFFKQQTIRELFDVTEGEKKEAEQSVP--------------QSDDEESINKQKTTILEQALCRAEDEEDIVAASQAKAEQVAELAEFNENIPLDDGDSRDQ-------EEEELSKAEQEIAALVEQLTPIERYAMNFLEASLEDICKEELKQAEEQVEAARKGLDQAKEEGLKLHQSSDSDEEDSVHPSTDEP-TPSRRPRKHKEKGAPSTRVSGRLRGTPADDISLTQTSPDRGRRTAWLNSERSISQTPGSTQKSPLNREVPEKLRSGPRGRCTTKESASLENQTIPTNQQLIDSTTLSPAMRDSYPKISVPSPHQQSISPSSSVPSAAASPSLDRNSCGHLSSSTVACREDSEDQKGEARSENVQSRDRRASASSDSICSPEHHSEQEGQLSLSPTLASPNSRSPRKRQSAEWEILKGLPEDSPSAKVLRKLPGRLVTVVEEKEPKRRRRGVSGSGGLHEGSSEEPEKTEPVQDTVPHSSDGSTQTFKVSPPKSVLTSLHSSPPPTPREQEQTSSPLPYSCTGRGHNPCSPTHHSPDMPVLRNLPVRRRLETESRLAAQLGEQFLGRGRGVDRKSASTQKRIETSTDKDGSTPCDSSLMSRRKRGRPPKTPPRALELSEENTPVIEKTSPERS-----PPHSPKRKRGRPRKDSTTTTGSPPSSPSAGAPSSQEPNLSRSNVMPETLPTDSKISPISSPTLCPTSPLNAAEVSSPPKPDSEIIQTTTSVLLSTSPSETGVDSHVDTYASPNTISSCNDSDNSTLVSLSHSTSTAAPYETCTDSSPTLQFTYSFREPPVTTVSICAEEIAHTSVLSDASEITAYSESLTVSTAAVEAEENSVTDNQQVNNLQPSNTSTQVTSQCEDETDPTTDLPQTTLEPIYSVAESSTPTDQPSIQPSSPPALTSEIEPEASSSILEAPETSAVQTVSTVQRSLPQSEQISPPSQLQTTAMEAVSDSPSQQISSSSLQSLSATNPVTTDSLSTLSTDADSSQSQNIVVETMIDNHEGPHSPKEKVETEEEEVLTEEEVVTEEEE-----------QEVVTETEVVTETEKMETDSVGEDDAGEKDDILSQPKKRRLECLPKDQTPSASGVASSDIESHDVQKSDGPDKPLEEEEPEDK---------EPRSSIRTRSISRQSSQETVRSSSPSSVSSCGTRSSRSKKAAENKNPVKRKRSEIKSEKKKSKEGSDKKHQSNSSSSSSDSEDSNSVKRCLTRSAQKKLEKEGMIAKNDESSTRQKARSDKKAKSTNSTEGESSGEVCSRVTRKSTGPQPNTLASPEPEVLGKRCSALNAAAKLLAMRARGPDTPSSSPKNKTAAHQSKTLTSEKVSKPKVNPGQDSPKVSNNKAESGKQPLGQSTESPQSSSSARSTRQRPGSLVPPLEVERVKKEEKKKPSDQKEEGEDEIRETRSSRGHSACSSISSERGVGSSRSRSSSNSSQRTHSLSSQSTDPIRTRSRATSSGSDTERSKSIQRKNDGGRGRESRKENKSQKLDKAELSAGSGDGTPDRVLRSVAALAAAHALTPACNTRSSTSQKRHSKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05471-1", "uniprot_id": "SWR1_YEAST", "id": "Q05471-1", "name": "Chromatin remodeling protein SWR1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSRKSHAKDKKAGGEQDLADLKFRYDLLTNELFHLREFVSLVDYDPTHFNDSESFQKFLRETHLSLEER---GEKFTDDVAKKGTNGDLTRRRRNLRTSTVVSSETTNE-----------------KKGDIELKLESIA-------------------------PLVRNKCEELKYKLSDHSNRKSIVPQKRPIQHLKKREAAKSLKFKSERKE-----------------NPLPLHEHIAEERYDHIAKVEEPSEAFTIKCPSDDSSFENTSEHYSDNFYFTTSSEEEDIKKKRGRKKKKPRIKLVVH---PPKQTITNPLHVVKPGYESLHEYIASFKS-LEDDLTLEEYNKYIDEQRRLLSRLKKG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IENGALKYDKETDSLQPITSKEIKTIITYKPDPISYFYKQQDLQIHTDHLINQGIHMSKLFRSSTKARIARAKKVSQMIEQHFKHVAGAEERKAKEEERHKKSLARFAVQAVKKRWNMAEKAYRILRKDEEEQLKRIEGKQHLSKMLEKSTQLLEAQLN----------------------------------QVNDDGRSSTPSSDSNDVLSESDD-----DMDDELSTSSDEDEEVDADVG-----------------------------------LENSPASTEATPTD--------------ESLNLIQLKEKYGHFNGSSTVYDSRNKDEKFPTLDKHESSSSESSVMTGEESSIYSSSENESQNENDRESDDKTPSVGLSALFGKGEESDGDLDLDDSEDFTVNSSSVEGEELEKDQ------------------------------------------------VDNSAATFER-----------------AGDFVHTQNENRDDIKDVEEDAETKVQEEQLSVVDVPVPSLLRGNLRTYQKQGLNWLASLYNNHTNGILADEMGLGKTIQTISLLAYLACEKENWGPHLIVVPTSVLLNWEMEFKRFAPGFKVLTYYGSPQQRKEKRKGWNKPDAFHVCIVSYQLVVQDQHSFKRKRWQYMVLDEAHNIKNFRSTRWQALLNFNTQRRLLLTGTPLQNNLAELWSLLYFLMPQTVIDGKKVSGFADLDAFQQWFGRPVDKIIETGQNFGQDKETKKTVAKLHQVLRPYLLRRLKADVEKQMPAKYEHIVYCKLSKRQRFLYDDFMSRAQTKATLASGNFMSIVNCLMQLRKVCNHPNLFEVRPILTSFVLEHCVASDYKDVERTLLKLFKKNNQVNRVDLDFLNLVFTLNDKDLTSYHAEEISKLTCVKN----------------------------------------------------------------------FVEEVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------KLRETNKQLQEEFGEASFLNFQDANQYFKYSNKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLEGTVDMLNFLKMVNKLRCDRRPIFGKNLIDLLTKDRRVK--------------------YDKSSIIDN---------ELIKPLQTRVLDNRKIIDTFAVLTPSAVSLDMRKLALGLNDDSSVGENTRLKVMQNCFEVSN-PLHQLQTKLTIAFPDKSLLQYDCGKLQKLAILLQQLKDNGHRALIFTQMTKVLDVLEQFLNYHGYLYMRLDGATKIEDRQILTERFNTDSRITVFILSSRSGGLGINLTGADTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIESNILKKANQKRQLDNVVIQEGDFTTDYFSKLSVRDLLGSELPENASGGDK----------------PLIADADVAAKDPRQLERLLAQAEDEDDVKAANLAMREVEIDNDDFDESTEKKAANEEEEN-----HAELDEYEGTAHVDEYMIRFIANGYYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9NDJ2-1", "uniprot_id": "DOM_DROME", "id": "Q9NDJ2-1", "name": "Chromatin remodeling protein domino", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNEGNSAGGGHEGLSPAPPAVPDRVTPHSTEISVAPANSTSTTVRAAGSVGAALPATRHHQHIATQVKGIASSSSKQQKQLASAQLPVPLSPLPQQQQQTAEATAAAAAPAHSNVSVSSSTIEASVLPPQAK---RQRLDDNEDRTSAASIVGPAESSNIVSSLLPASVASSSEVGGLSSTALQDLNALKKRILQQKLQILRNLKERHLENVSEYFYLQNGGSMMDYPAWRKKTPTPQFISYSNANRIDQLIHEDKPSTSAAAAAAQNQKYTTQQTDSVESSLVSGIGTGATKGAPLDGNISNSTVKTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATSTSATSAEASGNVLAVEAEIKIPAVGATPVAISTKLPAAVVQLTQQGGTPLLPCNTS-AGSTALRRPQGQNNASSGSAAASGGGGSLTPTPLYTGNGPAALGGSGGLTPGTPTSGSLLSPALG-----------------------------------------------------------------------------------------------------------------------------------------GGSGTPNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQERKWKKNAAKKCAKMVQKYFQDKATAAQRAEKAQELQLKRVASFIAREVKSFWSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQTEKFSQQLVEGMNK------------SVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEE-----DAADVKEEVTALAKESEMDFDDFLNDLPP------------------GYLENRDKLMKEEQSSAIKTETP--------------DDSDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKS-------------------------------------LMADADATSGAAGSGS-----------------TAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKLKRVGWTKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHR---------EFKEWFSNPMTGMIEGNMEYN-----ETLITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPR-----LVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSRLLAPPRK----------------------------------------------------------------------LIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIMPMR------------------------------------------------------------NLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLN---------HLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHALAAAEDEQDVQATKTAKAEVAADLAEFDENIPIATEDPNAEG-----GPQVELSKADLEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAELEAQKREWEANRLAAMHKEEELLKQETEAEEMLTYSRKDSSNQVWISRNTMEQMPMWCPPTPPQDNDNDIYIDYS------LSFMYELEPIAETDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRRELKSQRFRGSFKPNMPIPGLKPQLPTKPLTEPEAMAEWCVFEDMAILHVLVN----------------LQGLPCSLMLLSPGQTPNWDLVSEMVNFCSKTYRSARQCRWR----------------------------------------------------------------------YETHIQPREEGKVVESPKKQKKLKPTLRTEYLKSPLRYLRTTQLYVSDNNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSAPSLMNPKHMEVLQEFGILNYDQPVSPQNIAAMKANKIREKQRGQQMSQPPVGVGVVQQMQQQSQQQQQPAPPPLPQQQQPQQVVQQVQQQQQQQQQQQQQQVVQQQLPTVSNVQQTLPVQQTVELVQQQPTTTTTVAVPAAGGQLQQLQIQHLTSSNVSPGQQTAILLHQPQQQLRTHPGQGGQSNTQQLVKTIVGTSSSLTAGQLQQLAQQSAVASGGQSSVSVVLTTPVQTLPSVVQPQIGSGAQIVSISSQTLPVNSSPQLGSIVQTQSLPQVVSVSTLPTVGTVLTTTANQPQQQHQTTAVTTLNTTMLRGQRIVSTAAGNTLQQRTTAGGQSIVSMPNLGQGASPSQFQTQLRLAAVPTSPATQTTQLVTTKGIPVSALQQGGKTTVIPVTQQSGGAHIQLYRQRSLKVLQTTTQAVPSGSAGATGATANLVQAGGTIIQASNMATHVTSQKVAVSGMPGTSTTVQAGNVVSSVQMHGQARTQFIKQMAAGKQQLQRQVVSADGTTTTTAAGDMLLVKRHNILAAQKAQQASGALFTTTTGQQQQQQQQQGQLPVAGQPQQVTQHQIASLVKASTAAAASGSSVNAGGVTVSATNPTVQAGSVNMTLPQLKPGSQIKVTMPNQMRHLQMQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGVTVSGGGTLPTVASQQQQQQHQQKVGGGNSVQAQLLHIQNTKG-----------------------------------------------------------------------------LSNSVTMQQIQQVMRSGQQGTLATTNLVLGKTSVGRVIPVSVASQANQRQTIQVVSAASAQALAAGNLRTHVAGPSIASTLKVAAPGSAGGQTTQQTLIAALQHNQRQNASPVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAGPAEVMTITQTTTTLPTVGSLQQQQQQQQQQGGISQPTTQQVRKLVQKKILIRSEKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : . . . . . . : : : :: :. :. . : : * *:* :: :: * .. : : *:* :*: ::.:. :* : :: : : :* .: *: *. .** . :: . *: :: . :*. :: :: : : : : : * .. ..:.:: : :: * .* . ::. .. . : : : ..*: .. : : : .. :..: : * . . . .. . : :. : .: . :::: . .. . *. :.* : * .*:* **: ** **: **:**.:: :.: *****************:***:*** * *******:**:**:******:*::.*.**:*****: ::** ** **.**:******.**:**:**:::*:** *:*::****:*****:* *** ****.::************.* *****::**** .. . : *::**..*: :** . ::. : : :**:*:**:****:* :****** ****:: *:**:*** **:***::: *: ** :*:::*::* ************:*: ** :.* : . .:* *: . : . : :: . : .. . .. : : :. : :.. : *::* : : : : * :: * . *.. : : . : . ** : :: *** *:***.****.: **::** :***.*******::***** **.***::*:****:*::*:** * :*** * ** ****:****:*:********:********:** *.*****************::**:*:* ********** *.::.*: *:*** :*.. ::::*: * . :. :*: *. ****:*: *:. * * : :*:*. : . : : .. .: : :: . * ", "identical_positions": 349, "similar_positions": 334, "identity": "7.61%" }, { "cls_id": "homologset.agr.SGD:S000002743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQE8-1", "uniprot_id": "D3ZQE8_RAT", "id": "D3ZQE8-1", "name": "Exportin-5", "aln": "-MEMEQVNALCEELVKAVTVMMDPSSTQRYRLEALKFCEEFKEKCPICVPCGLKLAEKTQ-IAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMELIANGTLSILE-EENHIKDVLSRIVVEMIKREW--------------PQHWPDMLMELDTLSRQGETQRELVMFILLRLAEDVVTFQTLPT-QRRRDIQQTLTQNMERILNFLLS--------TLQENVNKYQQMKTDASQEAEAQANCRVSIAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQELQLGAAECLLIAVSRKGKLEDRKRLMILFGDVAMHYVLSAAQTADGGG---LVEKHYLFLKRLCQVLCALGNLLCALLALDANIQTPVNFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRHEVLSRDPSLLAVIPKYLRASMTNLVKMGFPSKTDSPS----CEYSRFDFDSDEDFNAFFNSSRAQHGEVVRCVCRLDPKTSFQMAAEWLKYQLSAAIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFRTLEKEELPVNEGIELLQ-LVLNFEMKDPLILSCVLTNVSALFPFVTYKP--------------AFLPQVFSKLFSFVTFESVGE---SKAPRTRAVRNVRRHACSSINKMCRDYPDLVLPNFDMLYSHVKQLLSN--ELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRALSDIDAFIAYVGADLKSCDPAAQDPCGLN--RARMSFCVYSILGVMRRTTWPSDLEEAKAGGFVVG-----YTPSGNPVFRNPCTEQILRLLDNLLALVRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEINDHPVYR--TILERMQR---FFGILYENCYHILGKAGPSMQQDFYTVEDLATQLLGSAFVNLNNIPDFRLRSMLH--ILKSRVFVKPLVLFCPPEHYETLISPILGPLFTYLHMRLSQKWHVINQRSVLCGEDEIAEDNPESQEMLEEQLVRMLTREVMDLIMACCVS-KKTAEHTATPTADGDDEEMMATEVAPSSVVELT-------------DLGKCLMKHEDVCTALLITAFNSLTWKDTLSCQRATTQLCWPLLKQVMSG-TLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIP-----EINKESLDQFDCKLLNPSLQ-KAADKRRKDHFKR-LIAGCIGKPLGEQFRKEVHIKNLPWLFKKSKP---MLETEVLD--SEE-GGLATIFEP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924C1-1", "uniprot_id": "XPO5_MOUSE", "id": "Q924C1-1", "name": "Exportin-5", "aln": "-MEMEQVNALCEELVKAVTVMMDPSSTQRYRLEALKFCEEFKEKCPICVPCGLKLAEKTQ-IAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMELIANGTLRILE-EENHIKDVLSRIVVEMIKREW--------------PQHWPDMLMELDTLFRQGETQRELVMFILLRLAEDVVTFQTLPT-QRRRDIQQTLTQNMERILNFLLN--------TLQENVNKYQQMKTDSSQEAEAQANCRVSVAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQELQLGAAECLLIAVSRKGKLEDRKRLMILFGDVAMHYILSAAQTADGGG---LVEKHYLFLKRLCQVLCALGNLLCALLALDANIQTPINFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRHEVLSRDPALLAVIPKYLRASMTNLVKMGFPSKTDSPS----CEYSRFDFDSDEDFNAFFNSSRAQHGEVVRCVCRLDPKTSFQMAAEWLKYQLSASIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFRTLDKEELPVSDGIELLQ-LVLNFEIKDPLVLSCVLTNVSALFPFVTYKP--------------AFLPQVFSKLFSFVTFESVGE---SKAPRTRAVRNVRRHACSSINKMCRDYPDLVLPNFDMLYSHVKQLLSN--ELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRALSDIDSFIAYVGADLKSCDPAVEDPCGLN--RARMSFCVYSILGVMRRTSWPSDLEEAKAGGFVVG-----YTPSGNPIFRNPCTEQILRLLDNLLALVRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEFNDHPVYR--TTLERMQR---FFGILYENCYHILGKAGPSMQQDFYTVEDLASQLLGSAFVNLNNIPDFRLRSML-------RVFVKPLVLFCPSEHYETLISPILGPLFTYLHMRLSQKWHVINQRSILCGEDEIAEDNPESQEMLEEQLVRMLTREAMDLIMACCVS-KKTADHTAAPTADGDDEEMMATEVAPSSVVELT-------------DLGKCLMKHEDVCTALLITAFNSLTWKDTLSCQRATTQLCWPLLKQVMSG-TLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIP-----EINKESLDQFDCKLLNPSLQ-KAADKRRKDHFKR-LIAGCIGKPLGEQFRKEVHIKNLPWLFKKPKP---MLETEVLD--SEE-GGLATIFEP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAV4-1", "uniprot_id": "XPO5_HUMAN", "id": "Q9HAV4-1", "name": "Exportin-5", "aln": "-MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQ-VAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILE-EENHIKDALSRIVVEMIKREW--------------PQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPP-QRRRDIQQTLTQNMERIFSFLLN--------TLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGG---LVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPS----CEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQ-MVLNFDTKDPLILSCVLTNVSALFPFVTYRP--------------EFLPQVFSKLFSSVTFETVEE---SKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSN--ELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLN--RARMSFCVYSILGVVKRTCWPTDLEEAKAGGFVVG-----YTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFK--TVLERMQR---FFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPML-------RVFVKPLVLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVS-KKGADHSSAPPADGDDEEMMATEVTPSAMAELT-------------DLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSG-TLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIP-----EIQKDSLDQFDCKLLNPSLQ-KVADKRRKDQFKR-LIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKP---MLETEVLD--NDG-GGLATIFEP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWE7-1", "uniprot_id": "Q9VWE7_DROME", "id": "Q9VWE7-1", "name": "", "aln": "MSQHGGTEALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLIEYTIKYRWNCITHEEKVYIKDNAIKMLNVGVGPAEDRSLLPTKDALSRIIVEMIKREW--------------PQQWSDLLPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLR--------LVEQHVTAFRETTR-LCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAFQCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQVLNGMAQQLVALWGKDDATQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAMVNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLATLVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVS-----CSVLDPVYLEWDALVSVLDGVLSRILLVAERP--SVPAGLRLLE-ECLKLETINPLTYSILLSCISALFVFLSMSACQITATNCVAMSGVSLLPRVLDKIFRALVMKPPNE---LEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPVFEQINGHVELLLKEPGKHQLCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWL--AFGDALKSPLDFMSFVGLDKPPIFAVEGAVTLQN--RSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIG-----CTELGNPICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGICALPTDPLDTTIRSEPTAFEKMQT---FMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSRMDLVPDYRLRPII-------RVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYIAS---LYESGQLDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANANSNSVAMENEEHSMDSAPQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGMCSMKAVNIAAPVMRFLAAEK-LMDENKAVTAFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQFPILSEVLQHIP-----SVNAADIQKFDEKIAVAPVKGNKVDRAKKDIFKK-LTAQLVGRSVNQLFRHEVQIANLPPMQSHKAKGSMGTTADIMD--SNQNASLARLFGPEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52918-1", "uniprot_id": "MSN5_YEAST", "id": "P52918-1", "name": "Protein MSN5", "aln": "-----MDSTGASQIVSALDVIYSPKSNNSQRQEAQKFLDEVK-LCSESPFWGYEIALQNPTNSILKYFGLGLLDHAVKKNWNDYDEGKRVALRKWVMELNFG----VQDYDTRYIKEKLATLWVEVAKRTWGEALKQTNPTEEQLLTSWVDMDNNLFELWNINQSSRELALIIFRILFEDVFLLDDLIVLKRMTVIQPLCVMIVCPIEVFAIKYKFSDKWTKFKANEEGWFSVWIPELNNALQQNNSEYIIRLLETLKTCLNWPLTEVIVRNDVLSSLLTCLSSNIPRAQSMALDSIHILLTRPYSNESHYQMTIDRVFDNMDLLDSVYESLLFDPTDDIDETKYPIIKKFVDMISCLYVCVPKIKETNGQIQK------YFKLVLKTTYNPSLIVSGLTLDLWCTCLRNDEYLP-KLEKYVIPDLLQFAADALVYYEQIDGHISKK------FAEIDFQSKSEFQTFCSTYRKRIRDIIRLISCVELDLTYDWLNNRLNNYFSSPFGQQVLSSTFLDHKLEPYLGALSQYMIVECFINGCIRWKIWYPTGDDYDEKLDSILQKLEILSNQLIALNLREPLLLKKQIQNFALFLTMLKDNV----------------LFTLLEKIITSATMDYPEINLEERGAESDAVRDLRYACGIELNRMALLMPESLKKIYPDLESVIARIMPN------LSYHEKISFKSFLLIIVLKSSLDMKEERFAAIVDPELLAWSDKTTVVGLSDLHWFMERLGIVQIAEYFQRRDIDENSDLLSIPIDDEGKELKSELTKRWQSLFPVRATRMFIHYSMQSIKTDEEFKMLQDLWRPRIVPILPYITRLLYQLQSYHDPDNWKGLPTVVQSFVKYSTIERFWEAGASNKSKDEFIDEHMKAMQTLRDFADSVGHIIRYTREYTLLVLSAISSLGSVFYLLDESPDLLLNSIAIFKPGSNEISPGVSTHGWKHIMNIAIRPILKGCPKDCLGKFMPAFLPKLFEILDLLLCQKWSSHMN--DMDMNPVPTDDDQMTEEILEENLLRQLTTVVVRIVIDCVGQ--GNANPNSAKSRLNNHQMEMR----------------------------KIIFNDLNTLAPFLKLLNHLISFKDTKCSFNSILVMKCCLTSVLNQNNTVDEYFTFEVMKNLLLNVLCNSAFKDSFHEALYAFTVIFLTLCKEYPSARAFLFEISNGYNIDELYRNLRSVDEYKTQRALMIDFIDWVKSTSGKEDGNVDHAGDERKRQEKREAILKKANERLIKKNK----ENGDMLDDPNIEDGAVGNLFDDN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . ::..*: :: .* : : * ** :..* .. . * :* . :::*** ::::.:* .** . ::* ::. .::: : . *: *: : **: ** * * *: :* .::. **.:::: * *** :: : :* : : * * : .: : : . : : : :.. * ** ::* . * .: *: * * * :.: .* . :.: : : : .. : * : ::*:: ::: : : : : : :: .* . :** : : * :::: **. :: :* * : .::.:*..:: : * ::.* :: :: : *: : . . :: . :: . : :. .: :.:*. : :: :** . : .: :: ::. * ::.*:: .:. . .: :.:::* . : ::. * : : : . : :: : . ::::*: . : : : :: * *.. *: :* . . : * * *: * : :: :*: :* : *: : . *: :. *: * : :. : .: . :: .* .*: :* : . :: . : .: .:*:: ** . .: .:: * : * ::* . : . : ::*:**::* * ** : :: . *: :: . .... * ::.. .* : ::::* .. .: : . : . :. :* .: :. .. : :: * .: .: .*. . .: ..* .: . * :. *. . * . ::*. : : : :::* . ..:. :* ", "identical_positions": 110, "similar_positions": 357, "identity": "8.42%" }, { "cls_id": "homologset.agr.SGD:S000002744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK22-1", "uniprot_id": "GTPB8_RAT", "id": "Q5BK22-1", "name": "GTP-binding protein 8", "aln": "--MAATRLWHRTGRLLEIASAFGPWPGVYSTSPAFAEVLRMPQKQLRKVVYPLRELEQHLVTDSRPGLIEQRLFDPSLEDIGRAESVFAATVRNRIEYLSSAVRLDHAPSLRQ---------------------PEVCFIGRSNVGKSSLIKALFSMAPDVEV----RISKKPGHTKKMNFFKVGKHFTLVDMPGYGYRAPEDFVDMVETYLKERNNLKRTFLLVDSVVGITKLDNIAIEMCEEFALPYVMILTKIDKSSKGYLLKQVLQIQEFVNTQTQGCFPQLFPISAVTYS---GVHLLKCFIADITG----SLK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CY28-1", "uniprot_id": "GTPB8_MOUSE", "id": "Q9CY28-1", "name": "GTP-binding protein 8", "aln": "--MAAARLSHRMGRLLEKAPALGPWTRVYSTSPAFAEVLRLPQKQLTKVVYPLRELGQHLAADSGPGLIEQRLFDPSLEDIGRAESIFEATARNRIEYLSSAVRLDHAPSLQQ---------------------PEVCFIGRSNVGKSSLIKALFSLAPDVEV----RISKKPGHTKKMNFFKVGKHFTLVDMPGYGYRAPEDFVDMVETYLKERNNLKRTFLLVDSVVGITKLDNIAIEMCEEFALPYVMILTKIDKSSKGYLLKQVLQIQKFVNTQTQGCFPQLFPISAVTNS---GVHLLKCFIADITG----SLK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3Z3-1", "uniprot_id": "GTPB8_HUMAN", "id": "Q8N3Z3-1", "name": "GTP-binding protein 8", "aln": "--MAAPGLRLGAGRLFEMPAVLERLSRYNSTSQAFAEVLRLPKQQLRKLLYPLQEVERFLAPYGRQD-LHLRIFDPSPEDIARADNIFTATERNRIDYVSSAVRIDHAPDLPR---------------------PEVCFIGRSNVGKSSLIKALFSLAPEVEV----RVSKKPGHTKKMNFFKVGKHFTVVDMPGYGFRAPEDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFVNMKTQGCFPQLFPVSAVTFS---GIHLLRCFIASVTG----SLD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S8I0-1", "uniprot_id": "GTPB8_DANRE", "id": "B0S8I0-1", "name": "GTP-binding protein 8", "aln": "-MLRIKALAPLQTRVSCWLLVLQRGHRLAS----IKHVCQLSERKRQSLLYPFSDLEGHLFSQVNQA--QFKIFHPSLEELRQAETLFTPSSKHVINYSTSAVRMDHVPILKQ---------------------PEVCFMGRSNVGKSSLIRALFSLAPEVEV----RVSKTPGHTKKLNFFTVGKAFTLVDMPGYGHMAPQDFVEMVEPYLQERHNLARTFLLVDASAGLQSTDLVAVEMFEEFNLPYVLVVTKIDRTRQGALLALALELQDFIKKQTTACFPQPFLVSSVQFS---GIHLLRCFIAHVTGKQLLSAKQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05473-1", "uniprot_id": "MRX8_YEAST", "id": "Q05473-1", "name": "MIOREX complex component 8", "aln": "MEQLCKRYVHTPAAFIQNIVANTKRTTLATQLSVEKAKKKVPKTALKKKLN-SRPKERLPNWLKLNDVFNIHYEKPSNSDINKVNRFFNKAKVEFEWCAASFDDIPENPFLNKKSHKDILKDHGECGTTLIDTLPEVIFLGGTNVGKSSILNNITTSHVSRDLGSLARVSKTTGFTKTLNCYNVGNRLRMIDSPGYGFNSSKEQGKVTLQYLLERKQLVRCFLLLAGDKEINNTDNMIIQYIHEHGVPFEVVFTKMDKVKDLNKFKKKVMSSGLMDLPTLPRLVLTNSLTSSTSPKRFGIDLLRYVIFQSCG----LIL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ::.: . : . : .** .:: :.: .* : . :* : . * * : *** *:* :******::. : : . :: *:**..*.**.:* :.**: : ::* ****. :.:: .:. ** **.:* * ***: . : . * : :: .*. :*: ::.**:*: . : : . ::. * : ::: . *:.**: .* * ", "identical_positions": 52, "similar_positions": 89, "identity": "16.2%" }, { "cls_id": "homologset.agr.SGD:S000002745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI37-1", "uniprot_id": "RT15_RAT", "id": "Q5XI37-1", "name": "Small ribosomal subunit protein uS15m", "aln": "-------------------------MLRAAWR-------ALSSVRVQAVTQAPVPALRAR--------SSASLP---SARCGLQTPS-LLNAARAY---AVQKPVQAKQDDEPASSTFIKEYKNIIPNMEKVDD---VVKRILSLEMASRKEKLKIKREQLMNKIAENPEDYRTLEARIVALTVKIRNYEEHMQKHRKDKVHKRHLLMSIDQRKKFLRLLRQTNYDVFEKTCKELGVEYALPPLHFQRVHRR--------------------------FLAKKALCIQVFQEVQKLKKQRM---------ALKAAAAAAKKEKRERVPENPSNALPEKTKEN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DC71-1", "uniprot_id": "RT15_MOUSE", "id": "Q9DC71-1", "name": "Small ribosomal subunit protein uS15m", "aln": "-------------------------MLRAAWR-------ALSSVRAQAVTRAPVPALRGG--------SSASLL---SARCGLQPPS-LLRAARAYA--AVQKPVQPKQDDEPPSSAFIKEYKDIIPNIEKVDD---VVKRILSLEMASRKEKLKIKQEQLMNKIVENPEDSRTLEAQIIALTVRIRNYEEHMQKHRKDKAHKRHLLMSIDRRKKLLKILRQTNYDVFEKTCKELGVEYTLPPLHFQKVHRR--------------------------FLAKKALCIRVYQEVQKLKKQKR---------ALKAAAAAAKKEKNEGVPENPSNAVPEKTQVN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82914-1", "uniprot_id": "RT15_HUMAN", "id": "P82914-1", "name": "Small ribosomal subunit protein uS15m", "aln": "-------------------------MLRVAWR-------TLSLIRTRAVTQVLVPGLPGG--------GSAKFP---FNQWGLQPRSLLLQAARGY---VVRKPAQSRLDDDPPPSTLLKDYQN-VPGIEKVDD---VVKRLLSLEMANKKEMLKIKQEQFMKKIVANPEDTRSLEARIIALSVKIRSYEEHLEKHRKDKAHKRYLLMSIDQRKKMLKNLRNTNYDVFEKICWGLGIEYTFPPLYYRRAHRR--------------------------FVTKKALCIRVFQETQKLKKRRR---------ALKAAAAAQKQAKR-RNPDSPAKAIPKTLKDSQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGL8-1", "uniprot_id": "RT15_DANRE", "id": "Q6DGL8-1", "name": "Small ribosomal subunit protein uS15m", "aln": "------------------------MVLKSVFRSTVLGLRTWSVFSVARQSKTTLPAFSQA--------QCSSYTNWTFSRHFKGDETLLNQPVRQYARPSRKKQEFPSQLEDLKTSMLKHEYAS-VPLAQSVDD---VVKKLLTLEFANHSEKLRLKEEQLIAKVQRDENDRSSTEVKVAILTARIRNFQEHLHKHPKDKANKRWMLMTIDKRKKLLKFLRRTRYDSFEKVCKELGITYTFPPEYYRRVTRR--------------------------WLAKKAFCNKVFKEVQRLKAAER---------EKQKAEEAERKKSS-------SSTNPQETAA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8WTC1-1", "uniprot_id": "RT15_DROME", "id": "Q8WTC1-1", "name": "Small ribosomal subunit protein uS15m", "aln": "--------------------------------------------------MNKLLNIAQA--------GHRQFVREYAFKSDLKIKWMRPEKIACYK---PEKSGDLAKLPPLKADELLPEYRD-CKELDKADE---SVKSLFKLSNNASYLTTKFYRDEMVKEVQRHAQDFGSMEAKLAKMTAVIRRYQEHMDKHPRDKMIKVRLKELIDKRKKFLKYLRRWDYPRFEWILEKLDLVYKPPPTHFHWITRKESLQKLTDIYCENLKEERLEAYHKQLQAQQIPFLEEAIKKMQFVRQEQISCDVPVTVTEEKIADSKRQLEMLKELQQAEAAASSKKQNEDGFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21771-1", "uniprot_id": "RT28_YEAST", "id": "P21771-1", "name": "Small ribosomal subunit protein uS15m", "aln": "MSIVGRNAILNLRISLCPLFMGKRSFVSSPVSNSAKAVKFLKAQRRKQKNEAKQATLKASTDKVDPVLGRADTPFITRIMAELKEPLVLSKGYNIEEVDKFLAAIESAKRERAELSGLNTEVVG-IEDIEKLEDRREAILRILSMRNSENKNAIKMAVELARKEFERFPGDTGSSEVQAACMTVRIQNMANHIKEHRKDFANTRNLRILVQQRQAILRYLKRDNPEKYYWTIQKLGLNDAAITDEFNMDRR---------------------------YMQDYEFFGDKILIRDSKKVANQ----------KRKEIRKQKRATF---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : : . :. :: : ::.: :: : :. * : *.: ::. *: :*:.:* :* . : :::*: :*: *:. : *.: . :. * . : : : . : : ", "identical_positions": 11, "similar_positions": 56, "identity": "3.19%" }, { "cls_id": "homologset.agr.SGD:S000002746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN35-1", "uniprot_id": "A0ABK0LN35_RAT", "id": "A0ABK0LN35-1", "name": "Multidrug and toxin extrusion protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MEPAEDS----LGAAIQPPELAPVPE-RSLRILLG--------------------LREALSSDVRQEAAALAALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLFLRQDPEVARLAQVYVMICIPALPAAFLFQLQTRYLQSQG------------------------------------IIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGS-AWANTTSQFFLSALLFLYVWWKGIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCTGVCALLVGILLAALKDVVAYVFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNAIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVFFQALSYLIYILRTNWNRVAEQAQVRAGLKSNKEMIPTPA----DLPILER--EVIDGVILPDIIRP-ESQTGQLVVEENSQCVV---PTVGEVLTGRQLVVYRGTALIVSIAVLIAGIVVRVINDRG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V050-1", "uniprot_id": "S47A2_MOUSE", "id": "Q3V050-1", "name": "Multidrug and toxin extrusion protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MEPAEDS----LGATIQPPELVRVPRGRSLRILLG--------------------LRGALSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQG------------------------------------IIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGS-AWANTTSQFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQVRAGLKSTKELIPTPA----DLPILER--EVMDGVILPDIIRP-ESQTGQLVVEENSQCAV---PTVGEVLTGRQLVFYRGMALTVSVAVLIAGIVVRVFNDRG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K0H1-1", "uniprot_id": "S47A1_MOUSE", "id": "Q8K0H1-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MERTEES----APG---PGGADAASERRGLRCLL--------------------------LPGFLEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQG------------------------------------IVLPQIMTGIAANLVNALANYVFLYHLHLGVMGS-ALANTISQFALAIFLFLYILWRRLHQATWGGWSWECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRGTGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLNWKRACQQAQVHANLKVNVALNSAVS----HEPAHPVCPESHGEIMMTDLEKKDETQLDQPMNQQQALPIR---PKDSNKLSGKQLALRRGLLLLGVVLVLVGGILVRVYIRIE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0E9-1", "uniprot_id": "S47A1_RAT", "id": "Q5I0E9-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MEVLEEP----APG---PGGADAA-ERRGLRRLL--------------------------LSGFQEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMVFIPALPAAFLYTLQVKYLLNQG------------------------------------IVLPQVITGIAANLVNALANYLFLHQLHLGVMGS-ALANTISQFALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRGTGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSGIIICSVCQTSCFLVFIARLNWKLACQQAQVHANLKVNVALNSAVS----QEPAHPVGPESHGEIMMTDLEKKDEIQLDQQMNQQQALPVH---PKDSNKLSGKQLALRRGLLFLGVVLVLVGGILVRVYIRTE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L1P9-1", "uniprot_id": "S47A1_DANRE", "id": "A1L1P9-1", "name": "Multidrug and toxin extrusion protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MDSITSYNVTQMNGDTKQEKCDDVLSTSSTQKFCGGC---------------RKKLRSLLPVNYKTEIVELLKLAGPVFISQLMIFLISFVSTVFCGHLGKTELAGVALAIAVINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQG------------------------------------IIWPQVITGAAGNILNALINYVFLHLLELGVAGS-AAANTISQYSLAVFLYVYIRWKNLHKATWDGWSRDCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLFFIILIYKLDWKKATQEALIRAGVQLTETKDESFG----LENKGCTEEAAKESQITEEGLTDANTDLEGLSKGGEGISEAGAKTTVGAVLTTKQLIVRRGLAVLLMVLILAGGIVLNEMLVRYLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86VL8-1", "uniprot_id": "S47A2_HUMAN", "id": "Q86VL8-1", "name": "Multidrug and toxin extrusion protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MDSLQDT-----------VALDHGGCCPALSRLVP--------------------------RGFGTEMWTLFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQGWLKGQEEESPFQTPGLSILHPSHSHLSRASFHLFQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGS-AYANIISQFAQTVFLLLYIVLKKLHLETWAGWSSQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVFLATAAFVAYTARLDWKLAAEEAKKHSGRQQQQRAESTATRPGPEKAVLSSVATGSSPGITLTTYSRSECHVDFFRTPEEAHALS----APTSRLSVKQLVIRRGAALGAASATLMVGLTVRILATRH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05497-1", "uniprot_id": "YD338_YEAST", "id": "Q05497-1", "name": "Uncharacterized transporter YDR338C", "aln": "MAGILSKTLSEVHPSLRTNGMGIGNTHRRISLGFLPPNKKNPLVRKFRARTRNIDQRSFRSLTDDFGSNVHEPNPYLGNIDEEPDLYYHDEEDGELSRTISLPSRVSETPELSPQDVDWILHEHERRYSSVCNSDNEEASQSNTPDRIQEYSGRELEYDEFMNRLQAQKQKLTRSAVTDAKGTSHHRRPSFVSVTSRGSVPTIYQEIDENDSEALAELAHSHVTFKSEARVLASYSFPLIFTFLLEQIFPMVCSLTVGHLGKNELAAVSLASMTSNIT-LAIFEGIATSLDTLCPQAYGSGRFYSVGVHLQRCIAFSLVIYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLILGAPAYIFFENLKRFLQAQG------------------------------------IFDAGIYVLTICAPLNVLVSYTLVWNKYIGVGFIGAAIAVVLNFWLMFFLLLFYALYIDGRKCWGGFSRKAFTHWNDLGHLAFSGIIMLEAEELSYELLTLFSAYYGVSYLAAQSAVSTMAALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVGLSFSFIAGFINCCILVFGRNLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCLRGQGMQSLGSIVNLMAYYLFGIPLALILSWFFDMKLYGLWIGIGSAMLLIGLVEAYYVLFPDWDKIMTYAEILKETEDD------------------------------------EVDSDEYLTDSDDPDEN--------------------TALLGA-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . * * : * :: :: :: ::.:: ***** ** .*:** *: ::: *:::: *** .*::*. . *** *** . *: :* .: :: :* . . :: *:. :: : : . *. ::: ::* ** * . : :* . :: :** * :: :* :: * *:: ..: .* **...::*: * ::*: :: . . *.**: :* : **.* .:.:.. .*:. :** *: *. : . :: :: :. :::.: ::: ::**: : . : *:.: *. :** * * .*: * : ** .*:* .: * : : : *** *: . :*. * : : . : . ", "identical_positions": 82, "similar_positions": 149, "identity": "10.16%" }, { "cls_id": "homologset.agr.SGD:S000002747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1RP75-1", "uniprot_id": "Q1RP75_RAT", "id": "Q1RP75-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "-GKQKKTRKY-----ATMKRMLSLR-DERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CTH6-1", "uniprot_id": "FCF1_MOUSE", "id": "Q9CTH6-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKQKKTRKY-----ATMKRMLSLR-DERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKFRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y324-1", "uniprot_id": "FCF1_HUMAN", "id": "Q9Y324-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKQKKTRKY-----ATMKRMLSLR-DQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL75-1", "uniprot_id": "Q9VL75_DROME", "id": "Q9VL75-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKHKKTQKVKKQRNAQLKRIIKPT-DARLK--DQIRVKRKKAEDPHQIKVHEATQQSSALFFQYNTQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIISDPRFERLPCLHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVAAHKYAIERMPEAYGVKA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05498-1", "uniprot_id": "FCF1_YEAST", "id": "Q05498-1", "name": "rRNA-processing protein FCF1", "aln": "MGKAKKTRKF-----GLVKRTLNTKKDQRLK---KNQENIKTKEDPELTR--NIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***:* . :** :. * *** : : : * :** : : .* .*.****** : ***::::*********: *:*:*:.***** *** * *:*** **:**** *:::**:: ***:.**.* ***********.** ********* * .**.*******:*:* :. * * **::*: : ", "identical_positions": 105, "similar_positions": 45, "identity": "51.47%" }, { "cls_id": "homologset.agr.SGD:S000002749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FFR1-1", "uniprot_id": "F7FFR1_RAT", "id": "F7FFR1-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKE---EVADFQLSVDSLLENNSHK-------------SQLDTQDQAQRLAEKLKCDTVVTAISAGPRTLNFKINRALLTKAVLQQVTEDGSKYGLKSELFSDLPQKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQANPLQHLFDVYVQVNKEATDD-------KNVTKLAHEFFHRLELGDTQALALWQRFRDLSIEEYTQIYKRLGIYFDEYSGES-FYREKSQDVLKLLDSKGLLQKTAKGNVVVDVSETGDLSSVCTVMRSDGTSLYATRDLAAAIHRKDKYNFDTMIYVADKGQKRHFQQVFQMLKIMGHEWAERCQHVPFGIVKGMKTRRGEVTFLEDVLNEVQSRMLQNMASIK-TTKKMENPRETAEKVGLAALIIQDFRGLLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEE---TFGCGYLNDFNVACLQEPQSVSILQHLLRFDEVLYTASQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPLAVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U186-1", "uniprot_id": "SYRM_MOUSE", "id": "Q3U186-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKE---EVADFQLSVDSLLEDNNHK-------------SQVDTQDQARRLAEKLKCDTVVTAISAGPRTLNFKINRELLTKAVLQQVTEDGCKYGLKSELFSDLPKKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQTNPLQHLFDVYVQVNKEATDD-------KNVTKLAHEFFHRLEMGDTQALSLWQRFRDLSIEEYTQIYKRLGIYFDEYSGES-FYREKSQDVLKLLDSKGLLQKTAEGNVVVDLSGTGDLSSVCTVMRSDGTSLYATRDLAAAIHRMDKYNFDTMIYVADKGQRRHFQQVFQMLKIMGYDWAERCQHVPFGIVKGMKTRRGGVTFLEDVLNEVQSRMLQNMASIK-TTKQLENPQETAERVGLAAVIIQDFRGTLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEE---TFGCGYLNDSNVACLQEPQSVSILQHLLRFDEVLYLSSQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPDVAGARLHLFKAVRSVLANGMKLLGITPVCRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T160-1", "uniprot_id": "SYRM_HUMAN", "id": "Q5T160-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------MACGFRRAIACQLSRVLNLPPENLITSISAVPISQKE---EVADFQLSVDSLLEKDNDH-------------SRPDIQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADD-------KSVAKAAQEFFQRLELGDVQALSLWQKFRDLSIEEYIRVYKRLGVYFDEYSGES-FYREKSQEVLKLLESKGLLLKTIKGTAVVDLSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQKKHFQQVFQMLKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIQLRMLQNMASIK-TTKELKNPQETAERVGLAALIIQDFKGLLLSDYKFSWDRVFQSRGDTGVFLQYTHARLHSLEE---TFGCGYLNDFNTACLQEPQSVSILQHLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPVCRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVZ0-1", "uniprot_id": "A0A8M3AVZ0_DANRE", "id": "A0A8M3AVZ0-1", "name": "Probable arginine--tRNA ligase, mitochondrial", "aln": "------MACFFRRSAALQLAKACGQNEETLIPLISVAPVNKKQ---SVADLRVSVSHLLQSGAVR-------------PDGDLQNTTHTLARQIRTDAVVEEVIPGRGVIHFRLNKLLLAQKLLDQLRSDPDGFGVKSEILRRLRVGRTLVEFSSPNIAKKFHAGHLRSTIIGNFIANLKKALGNEVIRVNYLGDWGMQFGLLGSGFERFGSQEKLRTQPLEHLFEVYVQVNREAESD-------ASVRSAAAHFFRRLEQSEEQALELWRHFREITIHEYKRIYQRLGVEFDHYSGES-FHRAETQTVLDELRSRRLLKTSQKGTGVVDLSDKGDMSNYATLVRSDGTSLYITRDVAAALDRKQRFSFDEMIYVTDKSQTMHFQQLFRILQAMGHPWAGSCHHVAFGLVQGMSTRRGEVLFLEDVLEEAQSRMIHNMRQSR-TSKELEDPEVTAERIGISALIVQDFKGPLISDYRFEWDKVLQAQGDTGVFLQYTHARLCSLLR---QQDC-EISCSDFSPLTDSRSVSLLQHLLRYDEVLLQCATDLQPKHLVNFLMTLSHLVASAHRELPVKGSSEAVAQARLCLFSSVRSVLANGMRILGITPVDKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05506-1", "uniprot_id": "SYRC_YEAST", "id": "Q05506-1", "name": "Arginine--tRNA ligase, cytoplasmic", "aln": "MASTANMISQLKKLSIAEPAVAKDSHPDVNIVDLMRNYISQELSKISGVDSSLIFPALEWTNTMERGDLLIPIPRLRIKGANPKDLAVQWAEKFPCGDFLEKVEANGPFIQFFFNPQFLAKLVIPDILTRKEDYGS----CKLVENKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLLAVGFERYGNEEALVKDPIHHLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKRMEDGDEEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSKESMLKAIDLFKEKGLTHED-KGAVLIDLTKFNKKLGKAIVQKSDGTTLYLTRDVGAAMDRYEKYHFDKMIYVIASQQDLHAAQFFEILKQMGFEWAKDLQHVNFGMVQGMSTRKGTVVFLDNILEETKEKMHEVMKKNENKYAQIEHPEEVADLVGISAVMIQDMQGKRINNYEFKWERMLSFEGDTGPYLQYAHSRLRSVERNASGITQEKWINADFSLLKEPAAKLLIRLLGQYPDVLRNAIKTHEPTTVVTYLFKLTHQVSSCYDVLWVAGQTEELATARLALYGAARQVLYNGMRLLGLTPVERM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ::: : : . : * : :.:: . .* : . * . . : : : *.:: . .: : .. ::* :* :*:: :: :: :* : : ::******:** **.*********.*:*** : ** :* *:**:**** *****. **: :* :* * :*:.***:***::*:: .: .. * .:*:*:* .: :** :*::**:::*.:* * **.: :* ***** . : . .:. : .: * :* ::*:: .. . . : :****:** ***:.**:.* ::: ** **** . * * *.*.:*: **. ** :** **:*:**.**:* * **:::*:* : :* . * . . . :::.*. .*: :*::*:::**::* :.:*.*.*::::. .**** :***:*:** *: . : : * :. : ::: * :: :** . :* :*.:*:.*:* .: .: * : ... :* *** *: :.*.** ***::**:**: ", "identical_positions": 173, "similar_positions": 204, "identity": "28.27%" }, { "cls_id": "homologset.agr.SGD:S000002750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLALLR--RPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLAMLR--RPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS-SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL-------LLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ--SSRVSWAEAW--EPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGA-------GVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN--KVN-VWAALN--RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ-------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGA-------LVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV--DAS-VKDLFS--NRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR--------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR-TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGS-------FMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ--ATQNTCLELF--KRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA--------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR-NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGS-------FMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ--ASRNTMLELL--KLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT--------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39004-1", "uniprot_id": "HXT7_YEAST", "id": "P39004-1", "name": "High-affinity hexose transporter HXT7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEHLSAVDS--------------------ASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFK-AVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWP---------------NGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFM-FFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . . . . :. : : : **: : : . : . .*:: *: * . *: .* :** * : * : : . : : : :*::* :: ..* :: . . : : : :**. * . .: : ** : : :* :.. . . :: **: * . * . : ::* :: :.*:.::::.* : :. * .: .*. :: : : . : :. : **:* : .:: ", "identical_positions": 33, "similar_positions": 101, "identity": "3.59%" }, { "cls_id": "homologset.agr.SGD:S000002751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLALLR--RPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLAMLR--RPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS-SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL-------LLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ--SSRVSWAEAW--EPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGA-------GVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN--KVN-VWAALN--RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ-------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGA-------LVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV--DAS-VKDLFS--NRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR--------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR-TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGS-------FMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ--ATQNTCLELF--KRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA--------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR-NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGS-------FMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ--ASRNTMLELL--KLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT--------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39003-1", "uniprot_id": "HXT6_YEAST", "id": "P39003-1", "name": "High-affinity hexose transporter HXT6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEHLSAVDS--------------------ASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFK-AVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWP---------------NGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFM-FFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . . . . :. : : : **: : : . : . .*:: *: * . *: .* :** * : * : : . : : : :*::* :: ..* :: . . : : : :**. * . .: : ** : : :* :.. . . :: **: * . * . : ::* :: :.*:.::::.* : :. * .: .*. :: : : . : :. : **:* : .:: ", "identical_positions": 33, "similar_positions": 101, "identity": "3.59%" }, { "cls_id": "homologset.agr.SGD:S000002753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSS--PAIPSLRRT-----APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLALLRR--PGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS--PAIPSLRRT-----APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGW-------VLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE--HQGFQLAMLRR--PGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTS--PVIPALKRS-----SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL-------LLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ--SSRVSWAEAWE--PRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS--PAETEIVDRG----EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGA-------GVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN--KVN-VWAALNR--PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ-------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS--NSTSNEND----------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGA-------LVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV--DAS-VKDLFSN--RASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR--------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS--PALVSMTDR-----TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGS-------FMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ--ATQNTCLELFK--RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA--------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS--PALVSMTDR-----NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGS-------FMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ--ASRNTMLELLK--LNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT--------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32466-1", "uniprot_id": "HXT3_YEAST", "id": "P32466-1", "name": "Low-affinity glucose transporter HXT3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLISPQKSSENSN---------------------ADLPSNSSQVMNMPEEKGVQDDFQAEADQVLTNPNTGKG-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFGMKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFN-AVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWP---------------NGEGNGSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMG-CMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . . . . :. : : : **: : : . : . .*:: *: * . *: .* :** * : * : : . : : : :*::* ::: ..* :: : : . : : : :**. * . .: : :* : : .* :... . . :: **: * . * . : ::* :: :.*:.::::.* : :. * .: .*. :: : : . .. :. : **:* : .:: ", "identical_positions": 32, "similar_positions": 106, "identity": "3.49%" }, { "cls_id": "homologset.agr.SGD:S000002757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5Z0-1", "uniprot_id": "BACE2_HUMAN", "id": "Q9Y5Z0-1", "name": "Beta-secretase 2", "aln": "MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDN--LQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIP-KGFNT-SFLVNIATIFESE--NFFLPGIK-WNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAG-----LPVAGSGTNGGSLVLGGIEPSLYKGDI-------WYTPIKEEWYYQIEILKL------EIGGQSLNLDCREYNADKAIVDSG-------TTLLRLPQKVFDAVVEAVARASLIPEFSDG---------------------------------FWTGSQLACWTNSETPWSYFPKIS-------IYLRDENSSRSFRITILPQLYIQPMMGAG------LNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG--AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06325-1", "uniprot_id": "YPS7_YEAST", "id": "Q06325-1", "name": "Aspartic proteinase yapsin-7", "aln": "---MTCLILWYLWLISTFQLEFATASTANTTTTAKSGTSSSTEEPFPVLAVGKDGRGN---YYVNSTFGTPGQRQRLLVDIIQPYINLVSGTSESHNEYSGVYHKHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCTLVTDDMNFTNVSSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSGKVTNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPIYIVSNSGQSLNMTSKDFLSPALLDSTSSVSYLPTSTIIQIAVQIAATYVESLDRWLVQCSIADMGVSLGFRLRELTIEIPLRDLLSSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFIKNIYMAMDLEDNTIAIAQAKKVEDDAVTEETNETTASTIIKKIKSGYIPYAKVMNSSNTRNLTLYPSYRSGYMFTVPGQLTAAYSNGVITGAGRSFYDTSRASTSARPSSTQFDSFSVSASEEWSNSTNRTSSASGAGVRLSSPYTFNKDPAG-HVTRIASLLLLSIFSILIVL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* * :: *.:. * . :.::. . * * .. : :.: ::.::.:*. .:*. : : :: ** . : *. :: . *:: .:*...*: *. . ..* :..::.* ::.* *.:: : :** **: *: :. .::*: : ** .*: .* : . :: ... : :::* **:.:*:* : * .: ** . .. :* *.*:***::***:.* : : *:.: *: * . .*****: .::: : : .:. :*::::. :: : **:: * : .::* *::..* **: . : . :* **: : ...:: *: :: :.: : : * * ::.: . * :* : . . . ..* *. .. . :.*. .::.. *:.: :.: .* . . : * * *: :: * . .*.. * *: :. ", "identical_positions": 84, "similar_positions": 209, "identity": "13.93%" }, { "cls_id": "homologset.agr.SGD:S000002760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMY1-1", "uniprot_id": "LAAT1_RAT", "id": "B0BMY1-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "MVWRTLVASNFSTCPNGSIQWIWDVFGECAQDGWDEASVALGLVSIFCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLL-----MLTLYFHY-----------KFKKQPSLLSAPINSVLL-------------------------FILG------------TVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVVGFVIGSASSVLYLLSRLPQIRTNFVRQSTQGISYSLFALVMLGNTLYG---------------LSVLLKNPEV-GQSEGSYLLHHLPWLVGS------------LGVLLLDTIISIQFLVYRS------------------HDADAASEREPLLPS------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4N4-1", "uniprot_id": "LAAT1_MOUSE", "id": "Q8C4N4-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "MVWRTLGASNFSTCPNGSVQWIWDVFGECAQDGWDEASVGLGLVSILCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLM-----MLTLYFHY-----------KFKKRPSPLSAPINSVLL-------------------------FILG------------TVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVIGFVIGSASSLLYLLSRLPQIRTNFIRQSTQGISYSLFALVMLGNTLYG---------------LSVLLKNPEV-GQSEGSYLLHHLPWLVGS------------LGVLLLDTIISIQFLVYRS------------------HETAAASEREPLLPS------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZP29-1", "uniprot_id": "LAAT1_HUMAN", "id": "Q6ZP29-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "MVWKKLGSRNFSSCPSGSIQWIWDVLGECAQDGWDEASVGLGLISILCFAASTFPQFIKAYKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLV-----MLTLYFYY-----------KFRTRPSLLSAPINSVLL-------------------------FLMG------------MACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYG---------------LSVLLKNPEE-GQSEGSYLLHHLPWLVGS------------LGVLLLDTIISIQFLVYR--------------------RSTAASELEPLLPS------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06328-1", "uniprot_id": "YPQ2_YEAST", "id": "Q06328-1", "name": "Vacuolar arginine/histidine antiporter YPQ2", "aln": "-----------MSCSNG---------------IWPTVSNLCGSLSFFTSVISLFPQIIETYRDKSVDG-LSPYFLLAWLCGDITSLIGAKLTGQLLFQILLAIYFLLNDSF-----VCGQYYYYGVLHENKLATVGHEPKPLLPELVENGELLREEED--------------------MIQGGSSAESPRSSRRRSAITAALAIAHTISTASAYPLNVGSTQSQVGPPGDGKNSQLGTILSWIGASFYVGARIPQLIKNYNRKSTDGLSPFLFATTLLCNITYN---------------LSIFTSCRFLDNQNKREFIVNELPFIFGS------------AGTIAFDLIYFYQYYILYATDMQLRELERELYSPEEDSAAQLVTERTSLLSGETQT--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1A4F0-1", "uniprot_id": "S66AL_HUMAN", "id": "A1A4F0-1", "name": "Putative uncharacterized protein SLC66A1LP", "aln": "-----------MKVVGN----------------YRVNTANSSTDTSGEHLTCLRSQLFVAYRNGRVDEAVSLGFLDCWIGGDLTNFKGCYLTNQLPIQIFTAIFDMNTDVI-----ILSQFMYYR---------------------------------------------------------------------------------------------------------LKNQKKKMIFQ------------PQLFKDSITR--EKVRLSLWGVLCPVYIPYS---------------FR-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGN8-1", "uniprot_id": "A0A8M2BGN8_DANRE", "id": "A0A8M2BGN8-1", "name": "", "aln": "----MDKSMFLDTVFRWSPEFVKGCLSTYEEHICTSAGFYILSALILLVSCSLLLYHRCSVKTRSKNWGDEAVCALYCFVGNLCSAVGAFLSNQFDFQISMASYMAIMDVVNFLSISFSMYLWFKSRTGRKMRMISRRRRQNFLAVCLLFIMAGSVYLGLPVRSIPVRASPTMRRLFGMFLNDHTENLGYVLGLLAFAISWTSKFPFILKASYLFQNRGEQGSAVLVSSRLLSSVAGALYGSAILLYDTQLKSVIKTMPWILSAICGSILDLSIVVLVCYRSSHKRPSVRSLDSDTESLLGEPSVTGQLCNNNECCRKKHHLSTARGISPKGTDMGLYMDVNIQPMRKVCLKEVTISRDGSSESLPLKRTVRVVRVDEHCSCGSSTDSSSLDSELEWDFGETKSQWTPVEEAPEDLQKVMPLQEWSVGSSGRLGSHVCFCNRAQLAEKLASK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : . : *: . *. *:.*: :* * : * . : : .. : * : ", "identical_positions": 8, "similar_positions": 22, "identity": "1.77%" }, { "cls_id": "homologset.agr.SGD:S000002761", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TY86-1", "uniprot_id": "AIFM3_MOUSE", "id": "Q3TY86-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF03-1", "uniprot_id": "D3ZF03_RAT", "id": "D3ZF03-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNIGTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSS-TNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDIENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NN9-1", "uniprot_id": "AIFM3_HUMAN", "id": "Q96NN9-1", "name": "Apoptosis-inducing factor 3", "aln": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29509-1", "uniprot_id": "TRXB1_YEAST", "id": "P29509-1", "name": "Thioredoxin reductase 1", "aln": "------------------------------------------------------------------MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEG--------------MMANGIAAGGQLTT----------TTEIENFPGFP----------------------------------------------------DGLTGSELMDRMREQ------------------------------------STKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGS-------------------------KVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT--------------------------VALEAKGDGKLLNALRIKNT---------------KKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGF-------FAAGDVQDSKYRQAITSAG-SGCMAALDAEKYLTSLE----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * : . .: : *. .:: : :* :.:*: : *:: * ::*:***: * :* : :*:: ..:* * :::.:: : .: . . :*. : . ::**.*:*.* : *:: * : .: .: : *.: .*:*.* . * * :**: . *:* * .. : : : *.::.: *:: :: :.*:::* : : :: : . ::*.:.::* : :* *:..* :::* :.: . . *: *. .. .*: : **::: *: *... .:*::: : ::.: ", "identical_positions": 53, "similar_positions": 139, "identity": "8.76%" }, { "cls_id": "homologset.agr.SGD:S000002766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0H9-1", "uniprot_id": "GGA1_MOUSE", "id": "Q8R0H9-1", "name": "ADP-ribosylation factor-binding protein GGA1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPAMEP---------------------------ETLEARINRATNPLNKELNWASINSFCEQLNEDFEGPPLATRLLAHKIQSPQ---EWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKSKILELLYSWTVCLP----EEVKIAEAYQMLKKQGIVKSDPKLPED-AIFPLPPPRPKNVIFED----EEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVN-AIEEVNNNVKLLTEMVMSHSQG-AASSSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATASSIPGSTS--------ALLDLSGLD------------------------LPPP--------GTTQPATPTRPGNQSSPEQL-SASVSLLDDELMSLGLSDPTPPSG--TSSDSVGWDNFQSSDGTESSVPPPAQAPSMDC-------RPPAQAPP------------PTSSGLDDLDLLG------KTLMQQALPPEAQQVRWE---------KQQPAPRLTLRDLQSKSS--------------SPSPGAASLLHTTSPEPPGP--------------PPQATPTEFSLTSITVPLESIKPSSILPVTVYDQHGFRVLFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLIFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLY6-1", "uniprot_id": "A0A8I6GLY6_RAT", "id": "A0A8I6GLY6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPAMEP---------------------------ETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQ---EWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLP----EEVKIAEAYQMLKKQGIVKSDPKLPED-AIFPLPPPRPKNVIFED----EEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVN-AIEEVNNNVKLLTEMVMSHSQG-AASSSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEELNGEATAGSIPGSTS--------ALLDLSGLD------------------------LPSS--------GTTYPATPTRPGNQNSPEQL-SASVSLLDDELMSLGLSDPTPPSA--PSSDSVGWNGFQSSDGTEPSVPPPAQAPCMDS-------RPPAQASP------------PTSSGLDDLDLLG------KTLMQQALPPEAQQVRWE---------KQQPAPRLTLRDLQSKSS--------------SPNPGATSLLHTTSPEPPGP--------------QPQAIPTELSLTNITVPLESIKPSSILPVTVYDQHGFRVLFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLIFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJY5-1", "uniprot_id": "GGA1_HUMAN", "id": "Q9UJY5-1", "name": "ADP-ribosylation factor-binding protein GGA1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPAMEP---------------------------ETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQ---EWEAIQALTVLETCMKSCGKRFHDEVGKFRFLN-ELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLP----EEVKIAEAYQMLKKQGIVKSDPKLPDD-TTFPLPPPRPKNVIFED----EEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVN-AIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVNGDATAGSIPGSTS--------ALLDLSGLD------------------------LPPA--------GTTYPAMPTRPGEQASPEQP-SASVSLLDDELMSLGLSDPTPPSG--PSLDGTGWNSFQSSDATEPPAPALAQAPSMES-------RPPAQTSL------------PASSGLDDLDLLG------KTLLQQSLPPESQQVRWE---------KQQPTPRLTLRDLQNKSSSCS-----------SPSSSATSLLHTVSPEPPRP--------------PQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JV04-1", "uniprot_id": "GGA3_RAT", "id": "A0A0G2JV04-1", "name": "ADP-ribosylation factor-binding protein GGA3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAEG---------------------------ESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQ---EWEAVQALTVLEACMKNCGRRLHNEVGKFRFLN-ELIKVVSPKYLGDRVSEKVKAKVIELLFSWTLALP----EEAKIKDAYHMLKRQGIVQSDPPIPMDRTLIPSPPPRPKNPVFDD----EEKSKLLAKLLRSKNPDDLQEANQLIKSMVKEDEARIQKVTKRLH-TLEEVNNNVKLLHEMLLHYSQE-FSSEADKELMKELFDRCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQIINGEVTTSTVPDSEGNSHCGNQGALIDLAELD--TPSSSSPVLAPAPAPPTSGIPILPPP----PQTSGPPRSRSSSQAEAPSGPDST-NNALSLLDEELLCLGLSDPAPTAP-KESAGNSPWHLFQNEPSSDLDFFSPRLVSAASCPSEGSLLPPPVSTSSLSQAPLPAAFPAPVVPASAVTHSTGSFTFSSGPAPALVPKAEPEGPEYP----SSSISHRLDALDQLLEEAKVTSGLVKPVSCFSPGPTASPLLPASTPARPLLPFSTGPGSPLFQSPAFQSQGSPQK-GPELSLASVHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPMKEKVRLRYKLTFALGEQLSTELGEVDQFPPVEQWGNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMI3-1", "uniprot_id": "GGA3_MOUSE", "id": "Q8BMI3-1", "name": "ADP-ribosylation factor-binding protein GGA3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAEG---------------------------ESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQ---EWEAVQALTVLEACMKNCGRRLHNEVGKFRFLN-ELIKVVSPKYLGDRVSEKVKTKVIELLFSWTLALP----EEAKIKDAYHMLKRQGIVQSDPPIPMDRTLIPSPPPRPKNPVFDD----EEKSKLLARLLKSKNPDDLQEANRLIKSMVKEDEARIQKVTKRLH-TLEEVNNNVKLLHEMLLHYSQE-YSSDADKELMKELFDRCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQIVNGEVTTSTMPDSEGNSHCGNQGALIDLAELD--APSNSS----PALAPPTSGIPILPPP----PQTSGPPRSRSSSQAEAPPGSDST-NNALSLLDEELLCLGLTDPAPTAP-KESPGSSQWHLFQNEPPSDLDFFSPRPVPAASCPSDGPQLPPPVSTSSMSQAPLPAAFPAPVVPASAPTHSTGSFMFSSGPAPALAPKAEPKGPEYP----SSSTSHRLDALDQLLEEAKVTSGLVKPVSCFSPGPTASPLLPASAPARPLLPFSTGPGSPLFQS-----QGSPQK-GPELSLASVHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPMKEKVRLRYKLTFALGEQLSTELGEVDQFPPVEQWGNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ52-1", "uniprot_id": "GGA3_HUMAN", "id": "Q9NZ52-1", "name": "ADP-ribosylation factor-binding protein GGA3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAEG---------------------------ESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQ---EWEALQALTVLEACMKNCGRRFHNEVGKFRFLN-ELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALP----EEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDD----EEKSKLLAKLLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLH-TLEEVNNNVRLLSEMLLHYSQE-DSSDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEVATLTLPDSEGNSQCSNQGTLIDLAELD--TTNSLSSVLAPAPTPPSSGIPILPPP----PQASGPPRSRSSSQAEATLGPSST-SNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQRE-QSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVK--------PTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPK-GPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQWGNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCV9-1", "uniprot_id": "A0A8M1NCV9_DANRE", "id": "A0A8M1NCV9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPEG---------------------------ESLESWLNKATNPSNRQEEWEYIIGFCDQINKELEGPQISVRLLAHKIQSPQ---EWESLQALTVLEACMKNCGGRFHNEVGKFRFLN-ELIKLVSPKYLGDRVSERVKTKVIELLYNCSVALP----DEAKIAEAYHMLKKQGIVTKDPEVHVDRTLIPSP--KTKNPVFDN----EEKSKRLAELLKSKKPEDLQEANRIIKNMVKEDEALQQKVSNRVS-TLEKVNNSVKLLNEMLSHFKTD-ESTQEDKELLKDLYNDCDNLRTAVFRLATETEDDDSALGDILHASDDLSRVINSYKKIVEGQTIVIDVPASTPSGCINDRSSSE--ILIDLADLGSGTPSPLRHGLTPPQHSDSPAADLLTLTSLMGAQPSSSNTSSGSSSFQTSPPSSQL-PSSLSLLDEELGSFGLGSLDSNSR--TSAEKT-----TKEAQSNQWISSQISNPVTDFLCSSTPLNPPNSAAP------------PTSKTTSITDFENSLQQSFKDLVLLDLDKTKSLSNYS-----SLSSRELAAGKENIHPALNTLSLSAG---------ITPLPSAGSSAK---PQSFAPDSPVFRSLSPTLPSSQSSSGSDISLTSVFVPLEAIKPSKECPVTAYDKDGVRVLLHFATDHPTGRPDVLVIVVSMLNTAPLLVRNVMLQAAVPKSMRVKLQPPSGTEMAPFNPFMPPSSITQIMLLANPLKEKVRMRYKLTFILGDQPVTASGEIDQFPLVEKWCHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5E6-1", "uniprot_id": "GGA2_MOUSE", "id": "Q6P5E6-1", "name": "ADP-ribosylation factor-binding protein GGA2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATAVAAG---TGSPAGTESAEGGP------------------------GAAAALELWLNKATDPSMAEQDWSAIQKFCEQVNTDPSGPTHAPWLLAHKIQSPQ---EKEALYALTVLEICMNHCGEKFHSEVAKFRFLN-ELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFP----EDIKIRDAYQMLKKQGIIKQDPKLPMD-KILPPPSPWPKS-IFDAD---EEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSRRVS-AVEEVRSHVRVLREMLSMYRRP-GHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVRLYKQVVEGRVSAGNAVPAAVG---------------AIPAPR-----------------------AFPNP-------EPCGLNCPLIDLET-----------PSLLHQDLAALGINDVPTRNQ----VVIPSCCNDKKQPGAITLMGGGIQSLSADR----------------------------------------------NLLDLFSPQPSPG-LNYVP---------QKSIPKEVPPGTKASPG---------------------------WSWEAGP-------------LASSTASQNTPLAHVFVPLESVKPSSLPPIVVYDRNGFRILLHFSQTGAPGHPDVKVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQTLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RAI4-1", "uniprot_id": "M0RAI4_RAT", "id": "M0RAI4-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "MAALRKSLLLAGPHVGALGHRVGRREASLGPDPGVTVRVRFAPSPTGFLHLGGLRTALYNYIFAKKHQGSFILRLEDTDQSRLVPGAAENIEDMLEWAGIPPDESPRQGGPAGPYYQSQRLALYAQATEALLKSGAAYPCFCSPQRLELLKKEALRSRQTPRYDNRCRNLSQAQVAQKLATDPKPAIRFRLEEAVPAFQDLVYGWTQHEVASVEGDPVILKSDGFPTYHLACVVDDHHMSISHVLRGSEWLVSTSKHLLLYQALGWQPPQFAHLPLLLNRDGSKLSKRQGDIFLEHFAATGFLPEALLDIITNCGSGFAENQMGRTLPELITQFDLTRITCHSALLDLEKLPEFNRLHLRRLVSSETQRPHLVEKLQGLVKEAFGSELQDRDVLDPAYMERILLLRQGHISRLQDLVSPVYSYLWTRPAVHRAELGASSEKLDVIAKHLLGLLERPGLSLTQDVVNRELKKLSEGLEGTKHSSVMKLLRMALSGQLQGPPVAEMMVSLGPEEVRERIQKPLWASHYRYLRKPEDGIGSPEAGVSDKATNPSMAEQDWSAIQKFCEQVNTDPSGPTHAPWLLAHKIQSPQ---EREALYALTVLEICMNHCGEKFHNEVAKFRFLN-ELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFP----EDIKIRDAYQMLKKQGIIKQDPKLPMD-KILPPPSPWPKS-IFDAD---EEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSRRVS-AVEEVRSHVRVLREMLSMYRRP-GHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVVEGRVNAGNAVPAAVG---------------AIPASR-----------------------VFPSP-------EPCGKNCPLIDLEA-----------PSLLHQDLAALGINDVPTRNQ----VVIPSCCKDKKQPGAITLMGGGIQSLSADR----------------------------------------------NLLDLFSPQPSPGPLNYVP---------QKSIPKEVPPGTKASPG---------------------------WSWEAGP-------------LASSPASQNTPLAHVFVPLESVKPSSLPPIIVYDRNGFRILLHFSQTGAPGHPDVQVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLTPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJY4-1", "uniprot_id": "GGA2_HUMAN", "id": "Q9UJY4-1", "name": "ADP-ribosylation factor-binding protein GGA2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATAVAAA------VAGTESAQGPP------------------------GPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQ---EKEALYALTVLEMCMNHCGEKFHSEVAKFRFLN-ELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFP----EDIKIRDAYQMLKKQGIIKQDPKLPVD-KILPPPSPWPKSSIFDAD---EEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSKRVS-AVEEVRSHVKVLQEMLSMYRRP-GQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLG---------------DIPVSR-----------------------VFQNP-------AGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPVTGM----VSGQNCCEEKRNPSSSTLPGGGVQNPSADR----------------------------------------------NLLDLLSAQPAPCPLNYVS---------QKSVPKEVPPGTKSSPG---------------------------WSWEAGP-------------LAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SRX1-1", "uniprot_id": "TM1L2_MOUSE", "id": "Q5SRX1-1", "name": "TOM1-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFL----LGNPFS---------------------------TPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLSGNR--NYREVMLALTVLETCVKNCGHRFHLLVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSP----DLTGVVHIYEELKRRGIEFPMADLDALSPIHTPQRSVPEMDPAATIPRSQTQPRTTAGTYSSPPPASYSTLQAPALSVTGPITANSEQIARLRS-ELDIVRGNTKVMSEMLTEMVPG-QEDSSDLELLQELNRTCRAMQHRIVELISRVS-NEEVTEELLHVNDDLNNVFLRYERFERYRS--------------------------------------------------------------------GRSVQNASNGVLS------------EVTEDNLIDLGPGSPAVVSP-----------MVGSTAPP-------------------------------------------------------------SSLSSQLAGLDLGTESVSG---------TLSSLQQCKPQDGFDMF-----------------------------------------------AQTR--GNSLAEQRKTVTYEDPQAVGGLASALDNR-------KQNSEMIP---------VAQPS----VMDDIEVWLRTDLKGDDLEEGVTSEEFDKFLEERAKAAETVPDLPSPPTEAPAPASNT---STRKKPER--SDDALFAL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVM7-1", "uniprot_id": "TM1L2_HUMAN", "id": "Q6ZVM7-1", "name": "TOM1-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFL----LGNPFS---------------------------TPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNR--NYREVMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSP----DLTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTSAGSYSSPPPAPYSAPQAPALSVTGPITANSEQIARLRS-ELDVVRGNTKVMSEMLTEMVPG-QEDSSDLELLQELNRTCRAMQQRIVELISRVS-NEEVTEELLHVNDDLNNVFLRYERFERYRS--------------------------------------------------------------------GRSVQNASNGVLN------------EVTEDNLIDLGPGSPAVVSP-----------MVGNTAPP-------------------------------------------------------------SSLSSQLAGLDLGTESVSG---------TLSSLQQCNPRDGFDMF-----------------------------------------------AQTR--GNSLAEQRKTVTYEDPQAVGGLASALDNR-------KQSSEGIP---------VAQPS----VMDDIEVWLRTDLKGDDLEEGVTSEEFDKFLEERAKAAEMVPDLPSPPMEAPAPASNP---SGRKKPER--SEDALFAL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSZ1-1", "uniprot_id": "Q9VSZ1_DROME", "id": "Q9VSZ1-1", "name": "TOM1-like protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASFFNVGALGNVFS---------------------------TPVGQRIEAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVKNCGKAFHVLVAQKDFIN-ELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQP----DLNGVTQMYMELKNKGIEFPANDLDAMAPIYTPQRSVPEMPPQLVA----AQQHTISPQHMAAAAAAAAAAAAPPS--TGPLHLTPEQAAKLRS-ELEIVSNNMSILSEMLSVLKPG-QESPDDYALLNELTSTCKEMQSRIVDLIGRVQ-DDELTAEFLRINDELNNVFLRHQRYEKNRSQG-----------------------------------------------------------------QGAGVTSPSAVLGA------------AMGLPGVGAAGAGATTVATLP----PPPTTTAVSNTPQSDQLLIDLIE----------------------------------------------------SSEEAQLP-QSLGQISLGGG-------APIGVQRSARPADEFDML-----------------------------------------------AQSRTDGNHKSDLLRDIPSVDAAAGSVTATASPYKPNQPQQAQRSAGEPP---------VVSKSTKENEIDEMEAWLGSSHIEG--IEELTSSEFDKFLEERAAAAENLPTISASNSAASATTGSAGADSLRKTPKKPGAEEDLLAL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06336-1", "uniprot_id": "GGA1_YEAST", "id": "Q06336-1", "name": "ADP-ribosylation factor-binding protein GGA1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQRIELTSEPVRKPR-----------------------STESSLLRKIQRACRSTLPEPDLGLNLDVADYINSKQGATPREAVLAIEKLVNNG--DTQAAVFALSLLDVLVKNCGYSIHLQISRKEFLNDLVKRFPEQPPLRYSKVQQMILEAIEEWYQTICKHASYKDDLQYINDMHKLLKYKGYTFPKVGSENLAVLRPNDQLRTPSELQEEQ--ERAQAAKLEELLRSGKPDDLKEANKLMKIMAGFKDDTKVAVKQAINNELNKLKRKADLFNEMLTSADEP----DLENEAIQELYGDLKSAQPKFKKLIEEERDDDALVSNLSKFNDLVIQLLKRYKSIKGMKEEELNVPDTNEP---------------------------------------------------------AKELNLIDFDDDTTANTPSVTSPSKSLQPFDDLLGDFNKVSLSSP-----------KSPQENDTVVDILGDAHSKS-------------------------------------------------SGIDLLDFDSQPGESKTALS---------AYSNSIVLPNGLLNSS--------------------------------------------------SNSKEITAQSQRHILNQSDHLRIDYELTRESMTKLRLVIFYSN------------------ISSDPITNFALLVASPKGTTLSLQPQSGNMLQSNSRDGIKQIASVEGISVN-LGKPIKLKWKANYCTKGDSKEESGTTSLPTI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . : ..: :* . .:: : :*::*: :: ** :* :.. *:: : :. :: . . : : . : ** :* . . : : . . . :: : :: **: . :: : : . * :: :: : .* : . . :: . . . . : : .. : :. : : . . ", "identical_positions": 15, "similar_positions": 82, "identity": "1.17%" }, { "cls_id": "homologset.agr.SGD:S000002769", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB65-1", "uniprot_id": "D3ZB65_RAT", "id": "D3ZB65-1", "name": "", "aln": "MADYSSGTQPGRFLVAPPPRRACVYRPHSPPPESDQRGSPEGRGRDPRRRSVTGNMASKAKKRAVGNGVQRPLEAPSQREEEEE--DELEDEEEDDEDSEEEEDDEDDEIVDEEVNIEFEAYSIS-DNDYGGIKKLLQQLFLKAPVNTAELANLLIQQNHIGSVIKQTDVS-----EDSDGEVDEDEIFGFISLLNLSERKGTQCAEQIKELVLSSCEKSCEQSMVEQLDKLLNDTSKPVGLLLSERFINVPPQIALPMHQQLQKELAEARRTNKPCGKCCFYLLISKTFVEAGKSTSRKRRDGLPQEALMFANAEEEFFYEKAVLKFSYSVQGESDTCLGGRWSFDDVPMK-PLRTVMLIPDDKMSEIMETLKDHLSI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWI3-1", "uniprot_id": "BCCIP_MOUSE", "id": "Q9CWI3-1", "name": "BRCA2 and CDKN1A-interacting protein", "aln": "-------------------------------------------------------MASKAKKRAVGNGIQRPLGAPGQREEEEEEEDEVEDEEEDEDDSDEEED-EVDEIVDEEVNIEFEAYSIS-DNDYGGIKKLLQQLFLKAPVNTAELTNLLMQQNHIGSVIKQTDVS-----EDSDDEVDEDEIFGFISLLNLTERKGTQCAEQIKELVLSFCEKTCEQSMVEQLDKLLNDTSKPVGLLLSERFINVPPQIALPMHQQLQKELSEARRTNKPCGKCCFYLLISKTFMEAGKSSSRKRQDSLQQGALMFANAEEEFFYEKAILKFSYSVQGESDTRLGGRWSFDDVPMT-PLRTVMVIPDDRMNEIMETLKDHLSV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P287-1", "uniprot_id": "BCCIP_HUMAN", "id": "Q9P287-1", "name": "BRCA2 and CDKN1A-interacting protein", "aln": "-------------------------------------------------------MASRSKRRAVESGVPQPPDPPVQRDEEEE--KEVENEDEDDDDSDKEKD-EEDEVIDEEVNIEFEAYSLS-DNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVS-----EDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMT-PLRTVMLIPGDKMNEIMDKLKEYLSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJJ7-1", "uniprot_id": "BCCIP_DANRE", "id": "Q5BJJ7-1", "name": "Protein BCCIP homolog", "aln": "-------------------------------------------------------MASSAKRRAVETGQN-----PQDSDESSD--EGLEDSGDDDSENS-------EEEVNEEVIVDFEAHTIS-DNDFHGIKTLLQQLFLKCHVNTSDLTDIIIQQNHIGSVIRQAEVP-----EDSDDEGDPDEVFGFISMVNLTERQGVECLEKLKDMILDQCVKCSTPDGQERMENLLQGNAQSVGLLLSERFVNVPPQIALPLHKQLQKEMAEAQRTNKPSGKCQFCLMISKTCKPLKKKS--ISAGDQAKDELLFVNDEEECFYEQATVKFSYCVQDEADSCATGKWSYDDEPMK-PFRTVMVIPMDRMDTIMQKMTDYLTV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFR0-1", "uniprot_id": "BCCIP_DROME", "id": "Q9VFR0-1", "name": "Protein BCCIP homolog", "aln": "-------------------------------------------------------MSANKQKKLS----------TMEVDPNEDVSSSSEDDDDDEPHPDAYKG-------NEEVQIDFEGRAPV-DPDAQGISQLLQRLFLRAHINCNQMADLIIAQNFIGSVICQCDDEGTESETEDDNMVEDGTIFGITSVLNLTAKKDQPSIAQLRTYILDRAKTHASPEVQQQLKEILDSEQRHVGFLINERFINIPAQISVPLLQSLQQEIEAAKAKKMKYDFGTLLLLVKFYRKESKKGK---------PGEDVYTNAEDELLSDRAKFSFEYSMASETDSGMSGDWLEGDAVMT-PYRKLLVLEAKKLPQLIDDIQRFINGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06338-1", "uniprot_id": "BCP1_YEAST", "id": "Q06338-1", "name": "Protein BCP1", "aln": "-------------------------------------------------------MVQAIKLNDLKNRKRKNVEEENGSDESEIDISSTDSENEEEQNGE-----------EEIVNIDFDFFGGNPEVDFHALKNLLRQLFGPQESTRIQLS--SLADLILGSPTTTIKTD-----------GKESDPYCFLSFVDFKANHLSDYVKYLQKVDMR---------LSTFFKTMIDSGNKNCALVLSERLINMPPEVVPPLYKITLEDVATALGDDKHYD---FYIIVTRKYEVNFDTD------DDTDSGKRNKNKDERSKKRVKADEVDYFHEEDRFFEKYAKIHFESEAKKGVISSYMILDHEGLVKSIDELETEISTW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : .. . :.. ::: . . :* * ::*: : * .:. **::** . ::: : : :** . . . : : *.:::. .: :: : :. :::. : .:::.**::*:*.:: *: : ::: * . . : :::. . * ::. ...* : . . . . ::: . : :: : :. ", "identical_positions": 20, "similar_positions": 98, "identity": "5.26%" }, { "cls_id": "homologset.agr.SGD:S000002772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC48-1", "uniprot_id": "PRP17_MOUSE", "id": "Q9DC48-1", "name": "Pre-mRNA-processing factor 17", "aln": "MSAAIAALAASYGSGSGSESDSDSEGSRCPLPAADSLMHLTKSPSAKLSLTVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSSVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGE---IVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIG-AVWHPHETSKVITCGWDGLIKLWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60508-1", "uniprot_id": "PRP17_HUMAN", "id": "O60508-1", "name": "Pre-mRNA-processing factor 17", "aln": "MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGE---IVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIG-AVWHPHETSKVITCGWDGLIKLWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VD52-1", "uniprot_id": "Q9VD52_DROME", "id": "Q9VD52-1", "name": "Pre-mRNA-processing factor 17", "aln": "MLGLQSYASSSDEESDHADAATATTNSEPSAPIPDHLLPVDKTHS--LSKSIAVCAAPTVVPLGASAVPRTLDPTLKEVTYNPRYEEMYAPVKGPEHPDLTMQQRAPRNTLAGYVEKAHINAFEFENQRRTFHTYGYALDPSVDDQADGQSFVGDLQSAYDDNGKTVFEP-PKAKKLRKQEKNDNPEDIEGFLGPWGKFENEVSVAKPNEQERAELDELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLGVNLRSNAPPTKCFLPKAHIHTWSGHNKGISSIRWFPKTAHLLLSGSMDCRVKLWEVYGERRCIRTFSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSRFTTRKMPFCVKFHPDNSKQHLFVAGTSDKKIICWDTRSGD---IVQEYDRHLGSVSTITFVDDNRRFVTTSDDKSMRIWEWDIPVDMKYIADPTMHSMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSPDMSYLVSGDGDGKCYIWDWKTTKMYKKWQAHDGVCIS-ALWHPHEASKVVTAGWDGQIKYWD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40968-1", "uniprot_id": "PRP17_YEAST", "id": "P40968-1", "name": "Pre-mRNA-processing factor 17", "aln": "-----------------------------------------------------------------------------------------------------------MGLVDGYDTSSDS-DLNFDEGKSVHEKK-------NGNLHEDTSYEPSSNNIHKRKSHFTKSELKRRRKTRKG---------DGPWGSWSSSDDE--TSQASETQKEDQDIFVHALAEDNLDSEQIEVEEVSHFYGKSEKDYQGRGYLYPPNDVDVDLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTN--PHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGNKPITQVDWHPQETSKVICSGAAGKIYVCD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** :. : *:: : .. . .: . .: . :. . :. . . : : ** :* *.*.. :* .::..* :: : * : : . *: ** : :: *. *****.**: *:*:.*:**. . :*:*** *: :.** :* :::: :* :.**:** . * :*:*:.* : .*:* * ** :.:: : :. .***:::** :*:**:***. :*: .. * *: .* : : *:.* *:.**: :* * .: :** **:**.:: :: :. :. :*:::*:**::*:** :* * :* *::.: **** :.: *. :::..**:**:* *. ::: : ** *.** :**. .: ** * *: ***...: ***:*::: .. : . * . ***:*:***: .* * * *", "identical_positions": 129, "similar_positions": 172, "identity": "22.13%" }, { "cls_id": "homologset.agr.SGD:S000002773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76MT4-1", "uniprot_id": "ESF1_RAT", "id": "Q76MT4-1", "name": "ESF1 homolog", "aln": "----------------------------------MSSKQEIMDDQRFRRVSKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHS-TTEDLKRFYDLSDSDSDLSDEESKVLDEKRVKEKKKQTKKETKS-KTPIEEKKKETKKTDQKDSINKNDLNNSERIQKMKNSHKSPKIDSEVSPK-DSEESLQ-SRKKKRDTTDLSVEASPKGKLRTKDPSTSAMVKSSTVSGSKAKREKQ---AVIMAKDNA-------GRMLHEEAPEEDSDSASELGRDEESEGEITSDDRASADDDENEDEEEEEDGEEEEEEEEEEDESDDESDSGPDLARGKGNVETSSEDEDDLADLFP-EEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKQRMKEEQIQGP-VELLS--IPEDAPEKDWASR------------------------EKLRDYQFKRLKYYYAVVECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP--KDAASEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKK--DELLDMDFEAYLASSSEDEEEVEEAPEGEDGVSI-EDGKTKKSQ---KDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQK----------ALAEEASEDEIPSDVDLNDPYFAEEVKK------IGIKKKSMKSAKDGATSEEETELEKQKAEMALLVMDEE-------EDSKKHFNYDKIVEHQN----LSKKKKKQLMKKK-------ELLEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHREQKEERLIQAVERAQQDTGKPAQKQPMDPALSMLIKSVKNKTEQFQARKKQRIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1V3-1", "uniprot_id": "ESF1_MOUSE", "id": "Q3V1V3-1", "name": "ESF1 homolog", "aln": "----------------------------------MSSKQEIMDDQRFRRVSKDPRFWEMPEKERKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHS-TTEDLKRFYDLSDSDSDLSDEESKILSQKKAKQKKKQTKKEAKSIEKPIEEKKKETKKTDQKDSINKHDLNNSERVQKMKNSQKPQKIDSEISPKKDNEEFLQ-NKKKKRGTTDLSVEALPKGKLRTKDSSTSEMVKSSTMSSSKAKREKQSVVPVIMAKDND-------GKMPDEDALEEDSDSASELGSDEESEDEIISDGKTSADEDESEEEDEE---EEEDSEEEEEEEEEDESDSGPDLARGKGNVETSSEDEDDLADLFP-EEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKERMKEEQVQGP-VELLS--IPEDAPEKDWASR------------------------EKLRDYQFKRLKYYYAVAECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP--KDVALEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKK--DELLDMDFQAYLASSSEDEEEVEEAPEGEEGVNIGEDGKTKKSQ---KDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQK----------ALAEEDSEDELPSDVDFNDPYFAEEVKK------IGIKKKSMKSAKDSASSEEETDLEKQKAEMALLVMDEE-------EDSKKHFNYDKIVEHQN----LSKKKKKQLMKKK-------ELVEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHRERKEELLIQAVERAQQDTGKPTQKQPMDPALSMLIKSVKNKTEQFQARKKQRVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H501-1", "uniprot_id": "ESF1_HUMAN", "id": "Q9H501-1", "name": "ESF1 homolog", "aln": "----------------------------------MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHS-TTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDS--KNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSCK-FKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEED--EDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFP-EESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGP-VELLS--IPEDAPEKDWTSR------------------------EKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP--KDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKK--EELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQ---KDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQK----------ALAEEASEEELPSDVDLNDPYFAEEVKQ------IGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDED-------EDSKKHFNYNKIVEHQN----LSKKKKKQLMKKK-------ELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQKVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46307-1", "uniprot_id": "O46307_DROME", "id": "O46307-1", "name": "", "aln": "MGKKKDKSGKLDKQTTKKEAPSSSQANMGKAAGANDSENGIWQDSRFQHLLTDPRFRGVPKVQRKVKIDKRFQGMFTDDKFKVKYTVDKYGRPVNKS-NAEDLRKFYELDENESSSGEEPAKKES--------------------------------------------------------------------------------------------------------------------------------------------------------DLDSEAEAEQQERRAEERAIANLEKEESNDT-----------LESDSSEVSQSLRQRLTNPEIDYARGEGRLYTDSSSDEDSDDEDEGPELQIDHVWGELDNDAEHTEESTRRLAVCNMDWDRIRAEDLMVMLSSFLPPGGSILSVKIYPSEFGKARMAEEEVHGP-KELVERVEPEDDSDEELVRQQDSDAEE-----------GEDYHMEKLRQYQLNRLRYYYAVVECDSIDTADKVYKECDGIEYESSATRVDLRFIPDDTSFEEDTPSDECFELPDASSYKPRQFTTTALQQAKVDLTWDETALDRRELGDKLSSGQVDKLTDKELRQIVAYSSEEEDSEAEESPAEEAAQKAVSEDPQKSKPKKTSKQERIATYKNLLADILEQEKKEKEQKYEMEMTWN---VEPQHEEAQPEQQAQAELTPIEKVIQKRSEKNRQRKEQRRQRQIEARGGDAGEDSDESMVPDGIDLNDAYFAEEFANGDYAPPKTKQDKKKKKKKGKDDGEEDVEAKRQEKELELLLDDGDG------RDEKQHFSLTKILKKEEQEASGSKRKRRQKLKKSKNQPQNAEKLDDDFQVNLNDNRFSAVYKSHEYNIDPTHSHYKPTKGMQQIIGEKLKRRKEQGE-GGAANGDADGDEQVAPKRSKQQLEQNALVKSLKRKIQLQQQGQKL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06344-1", "uniprot_id": "ESF1_YEAST", "id": "Q06344-1", "name": "Pre-rRNA-processing protein ESF1", "aln": "--------------------------------MAGENPKKEGVDARFAGIYSDPKFKNTKTKDHKIKLDSRFS--KKDLEVQHKSKVDKYGRKIKNAQNNRELEDFDKYFEKEAENDEDS-------------------------------------------------------------------------------------------------------------------------------------------------------------EVNAKTVVDRARGEVPDDYVSSSDEFTSSDS-----------------------------------------ESSGESEVESEEENE----------VEIENAKPESGDISKNLAVVNLDWDHVKSEDLMITFSSFVPKGGKIERVAIYPSEFGKERMQREEVEGPPKELFQKKNKNKTSKKKKTDDSDSDMDIGIKDLYEEGDADKDVDSRALRQYQLDRLRYYYAIVYCSDTTTSKAIYDNCDGTEYESTANMFDLRYVPDGMTFDDDVR-DECSILP--KNYRPHQFSTDALQHSSVKLTWDETPADRVEVAKRAFTQ--KEIDDMDFKAYLASDSDESDGQVDEEAKNKLKSLVGDFGFNSKK----------------------ETPNDEDEEVDMEITFTPALEGGNEKSSEDKEE-----TTIEKIRRKEKERRKARKQKVK---------ELKQQSEKD--------------------------KKSKLKSVNKKHTNDEEEIEKNAKSKAELELLMDDDDDTETQGTINNKAHFNMNEILRSEK-----EKHKKGRYQKKE-------RIVEDTFTPDLEDPRFKEVFEDHDFAIDPTQPEFKGTQAMSKILKERSKRVKNKKRKLGGSENNMTNNADD-------NEDIGNLVNKLKKKSKSSKKVKV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : * ** : .**:* ::*:*:*.** * :.: : *** ** :.:: . .:*. * . :.::. . : : ::.: : . : : . . ..: :....: : : *::: .: : ::.*** *:***:::::**: :.** * ** : * ******** ** .*::.** **.. :. ..:. . . **:**:.**:****:. *.. *:. :*.:*** *:**:.. .***::**. :*::: .: . *:*: *:: *: :.*.:***** :* .: . .:: * ::. :* .*::.: : :. . . :..: : : :::. :**:.: .: : : : *. *:. .*..*:.: :::: :: .:. .. . . * ** . :.: *: **: * : :.* **. :*:. :: .*:*: : **. . ::* * ::.* **. :: .* : :**:...:* *:.*.:*: *: :: :.: . : : : . *::.:* * : : : ", "identical_positions": 126, "similar_positions": 245, "identity": "13.12%" }, { "cls_id": "homologset.agr.SGD:S000002776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51652-1", "uniprot_id": "AKC1H_RAT", "id": "P51652-1", "name": "Aldo-keto reductase family 1 member C18", "aln": "-------------------------------MNSKIQ-----KMELNDGHSIPVLGFGTYAT-------------------------------------------EENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIE-DGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP------GDELLPQDEHGNLILDT--VDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKM-NDIVLVAYGALGT---QRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASDDMEILDNLDRNLRYFPAN---------MFKAHPNFPFS-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K023-1", "uniprot_id": "AKC1H_MOUSE", "id": "Q8K023-1", "name": "Aldo-keto reductase family 1 member C18", "aln": "-------------------------------MNSKIQ-----KIELNDGHSIPVLGFGTYAT-------------------------------------------EEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIE-DGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP------GNELLPKDEHGNLIFDT--VDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKM-NDIVLVAYGALGT---QRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLRYFPAD---------MFKAHPNFPFF-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23457-1", "uniprot_id": "DIDH_RAT", "id": "P23457-1", "name": "3-alpha-hydroxysteroid dehydrogenase", "aln": "-------------------------------MDSISL-----RVALNDGNFIPVLGFGTTVP-------------------------------------------EKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIE-DGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQP------GDIFFPRDEHGKLLFET--VDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKS-KDIILVSYCTLGS---SRDKTWVDQKSPVLLDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNFRYNNAK---------YFDDHPNHPFT-DE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AYQ2-1", "uniprot_id": "AK1CL_RAT", "id": "Q6AYQ2-1", "name": "Aldo-keto reductase family 1 member C21", "aln": "-------------------------------MNSKCH-----CVKLNDGHFIPVLGFGTAMP-------------------------------------------SELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIA-NGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKP------GDENFPVDEHGKLLFDT--VDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKT-NGIILVAYGVLGT---QRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMK-----LSPEDMKVLDDLNRNLRYIAGG---------IFEGHPNFPFL-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WR5-1", "uniprot_id": "AK1CL_MOUSE", "id": "Q91WR5-1", "name": "Aldo-keto reductase family 1 member C21", "aln": "-------------------------------MNSKCH-----CVILNDGNFIPVLGFGTALP-------------------------------------------LECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIA-DGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKP------GEENFPVDEHGKLIFDR--VDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKS-KDIVLVAYGVLGT---QRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAA---------IFKGHPNWPFL-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70694-1", "uniprot_id": "DHB5_MOUSE", "id": "P70694-1", "name": "Estradiol 17 beta-dehydrogenase 5", "aln": "-------------------------------MDSKQQ-----TVRLSDGHFIPILGFGTYAP-------------------------------------------QEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIA-DGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKP------GENYLPKDENGKLIYDA--VDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRS-KDIVLVAYSALGS---HREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIRYISGS---------SFKDHPDFPFW-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04828-1", "uniprot_id": "AK1C1_HUMAN", "id": "Q04828-1", "name": "Aldo-keto reductase family 1 member C1", "aln": "-------------------------------MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP------GEEVIPKDENGKILFDT--VDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGS---HREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD---------IFAGPPNYPFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52895-1", "uniprot_id": "AK1C2_HUMAN", "id": "P52895-1", "name": "Aldo-keto reductase family 1 member C2", "aln": "-------------------------------MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP------GEEVIPKDENGKILFDT--VDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGS---HREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD---------IFAGPPNYPFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42330-1", "uniprot_id": "AK1C3_HUMAN", "id": "P42330-1", "name": "Aldo-keto reductase family 1 member C3", "aln": "-------------------------------MDSKHQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------PEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP------GEELSPTDENGKVIFDI--VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKS-KDIVLVAYSALGS---QRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSD---------SFASHPNYPYS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17516-1", "uniprot_id": "AK1C4_HUMAN", "id": "P17516-1", "name": "Aldo-keto reductase family 1 member C4", "aln": "-------------------------------MDPKYQ-----RVELNDGHFMPVLGFGTYAP-------------------------------------------PEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP------GETPLPKDENGKVIFDT--VDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKS-KDIVLVAHSALGT---QRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMD---------FLMDHPDYPFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC28-1", "uniprot_id": "AK1CD_MOUSE", "id": "Q8VC28-1", "name": "Aldo-keto reductase family 1 member C13", "aln": "-------------------------------MSSKQH-----CVKLNDGHLIPALGFGTYK-------------------------------------P------KEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIK-AGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKS------GDNDFPVNEQGKSLLDT--VDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCES-KDIVLVAYGALGT---QRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAE---------FLVDHPEYPFV-EEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AD50-1", "uniprot_id": "A0A8I6AD50_RAT", "id": "A0A8I6AD50-1", "name": "", "aln": "-------------------------------MAASCHYWAMALFKIQSSEYVNQISFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCSPGVSASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIK-AGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKS------GDNDFPVDEKGKSLLDT--VDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSKLLDYCKS-KDIVLVAYGALGT---QRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLVQRGVVPLAQSFKENEMRENLQVFDFQLSPEDMKTLDGLNKNFRYLSAE---------FLAGHPEYPFS-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9Y6-1", "uniprot_id": "G3X9Y6_MOUSE", "id": "G3X9Y6-1", "name": "", "aln": "-------------------------------MSSKQQ-----CVKLNDGNFIPALGFGTYK-------------------------------------P------EEVNENKPLEAIHLALEAGFRHIDTAYVYQTENHVGQAIRSKIA-AGLVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQMKP------GEDLFPEDEHGKTLFDT--VDICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQRKLLNYCKS-KDIVLVAYCALGS---QRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALRYHLQRGIVVLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNLRYAPAP---------FGEGHPEYPFS-DEF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADN4-1", "uniprot_id": "A0A8I6ADN4_RAT", "id": "A0A8I6ADN4-1", "name": "", "aln": "-------------------------------MSFKQQ-----CVELSDGRLMPLLGYGTFQ----------------------------------------------------------------------------------------------------NPELWSTFHRPELVRVGLERSLKSFQLDYVDLYLIHYPISIKP------SEEIYTKDENGKILFET--VDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKHRPVCNQVECHPYLNQSKLMDFCKS-QDIVLVAYAALGS---QRPTNWVDKNAPFLLNDPVLGGMAKKHNRSPAQIALRYQVQRGVVALAQTYEQKEMKENIQVFEFQLPSEDMEVLDGLNRNFRYFPVN---------IAAEHPNYPYS-DDY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZF77-1", "uniprot_id": "AK1CA_RAT", "id": "D3ZF77-1", "name": "Aldo-keto reductase family 1 member C15", "aln": "-------------------------------MDLKHSR----SVKLNDGNLMPVLGFGTFAS-------------------------------------------KEIPKSKAAEATKVAIDVGFRHIDAAYFYQNEEEVGQALRDKMA-DGTVKREDLFYTTKIWITFLRPELVRQCLERSLKKLGLDYVDLCIIHIPIAMKP------GEELLPKDANGKFIFDT--VDIRDTWEALEKCKDAGLSKSIGVSNFNHKQLELILNKPRLKYKPTCNQVECHPYLNQSKLLEFCKS-KDIVLVAYSALGS---HRDSSWVSSDSPYLLEDPVLMTIAKKHNQTPGQVALRYQLQRGVVVLAKSFNEKRIKENFQVFDFELTPEDMKTIDSLNRNFRYSQMA---------FALDHPDYPFL-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCX1-1", "uniprot_id": "AK1D1_MOUSE", "id": "Q8VCX1-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MNLSAAH---HQISLSDGNNIPLIGLGTYSDP------------------------------------------RPVP-GKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIA-EGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKP------GKEIYPRDENGRIIYDK--TNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTNQVECHPYFTQTKLLKFCQQ-HDIVIVAHSPLGT---CRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFDFSLTEEEMKDIDALNKNVRYVELL---------MWSDHPEYPFH-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31210-1", "uniprot_id": "AK1D1_RAT", "id": "P31210-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MNLSTAN---HHIPLNDGNSIPIIGLGTYSDP------------------------------------------RPVP-GKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVA-EGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKP------GEEFYPKDENGRVIYHK--SNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGT---CRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKEEMKDIEALNKNVRFVEML---------MWSDHPEYPFH-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51857-1", "uniprot_id": "AK1D1_HUMAN", "id": "P51857-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MDLSAAS---HRIPLSDGNSIPIIGLGTYSEP------------------------------------------KSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIA-EGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP------GDEIYPRDENGKWLYHK--SNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQ-HDIVITAYSPLGT---SRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELL---------MWRDHPEYPFH-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y112-1", "uniprot_id": "Q9Y112_DROME", "id": "Q9Y112-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "-------------------------------MSSKIP-----YVKHNNGTQIQSIGLGTYTS----------------------------------------------LGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIA-EGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYR----GDNEMMPTDAKGEVELND--IDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLAN--CKIKPIHNQIECHPALNQKKLIALCKK-NDIVVTAYCPLGR---PNP----AEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMT---------HAIKSKNYPFN-IEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZK8-1", "uniprot_id": "Q9VZK8_DROME", "id": "Q9VZK8-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "-------------------------------MTGKVEY----YFKHNDGTHIQGIGLGTFAS----------------------------------------------TEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIA-EGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYR----GDNELIPKDANGEVELVD--IDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLAN--CKIKPIHNQIEVHPALDQKKLIALCKK-NGILVTAFSPLGR---HNA----ELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHAR---------QAIKSKYYPFN-VYSACF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "---------------------------------MKLAP----TVKLNNGYEMPILGLGTYNS----------------------------------------------KDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIA-EGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYV----DDNTLLPKNEDDVLQLSD--VDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPALNQKALTAFCKK-NDVTLTGYTPLGK---PKP----DIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNL-------IKGLNHKYYPFS-IEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5RJP0-1", "uniprot_id": "ALD1_RAT", "id": "Q5RJP0-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "-----------------------------------MTT----FVKLRTKAKMPLVGLGTWKS----------------------------------------------PPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIK-EKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQA------GKEFLPKDSQGKVLMSK--STFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGIAVIAYSPLG----SPDRPYAKPEDPVVLEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG---------LFVTSDEEDFPFH-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21300-1", "uniprot_id": "ALD1_MOUSE", "id": "P21300-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "-----------------------------------MAT----FVELSTKAKMPLVGLGTWKS----------------------------------------------SPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIK-ENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQA------GNALLPKDNKGKVLLSK--STFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQS-KGIAVTAYSPLG----SPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACD---------LLDARTEEDYPFH-EEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E895-1", "uniprot_id": "G5E895_MOUSE", "id": "G5E895-1", "name": "aldose reductase", "aln": "-----------------------------------MAA----FVTLLTGAKMPIVGLGTWKS----------------------------------------------PPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ-EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQS------GNVFLPTDDKGSILSSK--YTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGITITAYSPLG----SPDRPSAKPEDPLLLEIPKIKEIAAKHKRTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWRACG---------LFAASHNEDFPFH-AEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45377-1", "uniprot_id": "ALD2_MOUSE", "id": "P45377-1", "name": "Aldose reductase-related protein 2", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWKS----------------------------------------------PPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIK-EKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQP------GKELFPKDDQGRILTSK--TTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGISVTAYSPLG----SPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACL---------LPETVNMEEYPYD-AEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60218-1", "uniprot_id": "AK1BA_HUMAN", "id": "O60218-1", "name": "Aldo-keto reductase family 1 member B10", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWKS----------------------------------------------PLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ-EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS------GDDLFPKDDKGNAIGGK--ATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS-KGITVTAYSPLG----SPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN---------VLQSSHLEDYPFN-AEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JRZ8-1", "uniprot_id": "AK1BF_HUMAN", "id": "C9JRZ8-1", "name": "Aldo-keto reductase family 1 member B15", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWRS----------------------------------------------LLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQ-EKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKT------GDDFFPKDDKGNMISGK--GTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS-KGITVTAYSPLG----SPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD---------FKEFSHLEDFPFD-AEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07943-1", "uniprot_id": "ALDR_RAT", "id": "P07943-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----HLELNNGTKMPTLGLGTWKS----------------------------------------------PPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKP------GPDYFPLDASGNVIPSD--TDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHC-KGIVVTAYSPLG----SPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA---------LMSCAKHKDYPFH-AEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A068-1", "uniprot_id": "A0A8I6A068_RAT", "id": "A0A8I6A068-1", "name": "aldose reductase", "aln": "-----------------------------------MAS----YLELNSGTKMPTLGLGTWKS----------------------------------------------PPGQVTEAVKVAIDMGYRHIDCTRVFQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLTHWPTGFKP------GPDYFPLDALGNVIPSD--TDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHC-KGIMVTAYSPLG----SPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIWFPIQRNLVVIPKSVTPARIADNFKVFDFELSSEDMATLLSYNRNWRVCA---------LMSCVKHKDYPFH-AEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45376-1", "uniprot_id": "ALDR_MOUSE", "id": "P45376-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----HLELNNGTKMPTLGLGTWKS----------------------------------------------PPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKP------GPDYFPLDASGNVIPSD--TDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHS-KGIVVTAYSPLG----SPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCA---------LMSCAKHKDYPFH-AEV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15121-1", "uniprot_id": "ALDR_HUMAN", "id": "P15121-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----RLLLNNGAKMPILGLGTWKS----------------------------------------------PPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR-EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP------GKEFFPLDESGNVVPSD--TNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS-KGIVVTAYSPLG----SPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA---------LLSCTSHKDYPFH-EEF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCT1-1", "uniprot_id": "AKCL2_MOUSE", "id": "Q9DCT1-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "------------------------------------------------MENIPTVGLGTWKA----------------------------------------------SPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIK-EGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKP------GEKDIPLDRNGKVIPSH--TSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHK-RNVSVTAYRPLG----GSG------GGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLAT---------FPTTENHQDYPFH-IEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U1Y4-1", "uniprot_id": "AKCL2_RAT", "id": "Q5U1Y4-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "------------------------------------------------MHQIPTVGLGTWKA----------------------------------------------SPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIK-EGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKP------GDKDIPLDRSGKVIPSH--TSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHG-RNVSVTAYRPLG----GSR------DGVHLMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFDFELTEKDMEELLSLDKNLRLAT---------FPSTENHKDYPFH-IEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PF61-1", "uniprot_id": "ALDR_DROME", "id": "M9PF61-1", "name": "Aldo-keto reductase 1B", "aln": "MNTLMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAP----KVVCLDGNEIPVIGLGTFNS----------------------------------------------PKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIK-EGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKE------GCDLFPTDKDGKTLYSP--VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIP--PVTNQIECHPYLTQKKLIDFCKS-KDITITAYSPLG----SPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVP---------LLNQYGHPHHPFEKDEY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51635-1", "uniprot_id": "AK1A1_RAT", "id": "P51635-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MTAS----SVLLHTGQKMPLIGLGTWKS----------------------------------------------EPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFER------GDNPFPKNADGTVKYDS--THYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVR--PAVLQVECHPYLAQNELIAHCQA-RGLEVTAYSPLG----SSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFN-DPY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII6-1", "uniprot_id": "AK1A1_MOUSE", "id": "Q9JII6-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MTAS----SVLLHTGQKMPLIGLGTWKS----------------------------------------------EPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER------GDNPFPKNADGTVRYDS--THYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--PAVLQVECHPYLAQNELIAHCHA-RGLEVTAYSPLG----SSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFN-DPY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14550-1", "uniprot_id": "AK1A1_HUMAN", "id": "P14550-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MAAS----CVLLHTGQKMPLIGLGTWKS----------------------------------------------EPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER------GDNPFPKNADGTICYDS--THYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--PAVLQVECHPYLAQNELIAHCQA-RGLEVTAYSPLG----SSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFN-DPY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568L5-1", "uniprot_id": "A1A1B_DANRE", "id": "Q568L5-1", "name": "Aldo-keto reductase family 1 member A1-B", "aln": "-----------------------------------MND----FAVLSTGRKMPLLGLGTWKS----------------------------------------------EPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQR------GDTPFPRKEDGTLLYDD--IDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIK--PTVLQVESHPYLAQVELLSHCRD-RGLVMTAYSPLG----SPDRAWKHPDEPVLLEEPAIAALAKKYNKTPAQIIIRWQTQRGVVTIPKSITQSRIKENIQVFDFTLESEEMSQVTALHRGWRYIVPTITVDGKSVPRDAGHPHYPFN-DPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AZW2-1", "uniprot_id": "A1A1A_DANRE", "id": "Q6AZW2-1", "name": "Aldo-keto reductase family 1 member A1-A", "aln": "-----------------------------------MTA----TITLSTGQRMPTVGLGTWKS----------------------------------------------APGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGR------GDELIPRHPDGTIQYDD--THYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHK--PVVNQVECHPYLVQAELVSHCWS-RNLTVTAYSPLG----SPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRIKQNIEVFDFKLSDEDMRLIESFNRNERFIIPTVIKDGQKIWRDAKHPHFPFI-EPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PA35-1", "uniprot_id": "A0A8M1PA35_DANRE", "id": "A0A8M1PA35-1", "name": "alcohol dehydrogenase (NADP(+))", "aln": "-------------------------------MEEGVQK--PRKIELNDGTFMPLLGLGTWKP-------------------------------------------ESTGPDMCQRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQ-QGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSDLQLDYLDQYLVHFPVGLKK-----VGDELFP-ERDGKILTTD--IDYVDVWRGMEALKATGKVKSIGVSNFTMEQIDRLLSVAKIP--PAVNQVELHPYLVQSDLIDYCKS-KNIALTAHSPFGSPGRPLEFQTGDKDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHHILENTKIFDFTLDEEDMNALKSLNRGWRACIIT---------ELEAHYFYPFK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "-------------------------------MPATLKN-SSATLKLNTGASIPVLGFGTWRS----------------------------------------------VDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK-----DSGVPREEIFITTKLWGTEQRDP--EAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKE-KGIVVEAYSPFGS------------ANAPLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFT--LPEDDFKTISNLSKVHGTKR----------VVDMKWGSFPIFQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. * ::* * :.* * : . * . . . : :: * : :*:***. : :* * *:* : : : . : .. :* : : :. : : : : .: . . . .: : * ", "identical_positions": 17, "similar_positions": 46, "identity": "3.97%" }, { "cls_id": "homologset.agr.SGD:S000002779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RY07-1", "uniprot_id": "CHIA_RAT", "id": "Q6RY07-1", "name": "Acidic mammalian chitinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILVTGLVLLLNVQL----------GSAYNLVCYFTNWAQYRP-------------GLGSFKPDDINPCL--------CTHLIY-AFAGMQNNQITTIEW-NDVTL--------YKAFNDLK--NRNSKLKTLLAIGGWNFGTA---------PFTTMVSTSQNRQTFITSVIKFLRQY-GFDGLDLDWEYPGSRGSPPQ--------------------------DKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDG--YTGENSPLYKLPTETGSNAYLN----VDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGIGAPTS----GNGPAGPYTRQAGFWAYYEICTFLRN------------GATQDWDAPQEVPYAYKGN-------EWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQG-----------------------------------------------------KFPLTSTLNKALDIPTAGCTAPDLPSEPVTTPP--------------GSGSGGGSSGGGSEGSGFCAGKADGLYPVA--------------------DDRNAFWHCINGITYQQHCQAGLVFDTSCNCCNWP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XA9-1", "uniprot_id": "CHIA_MOUSE", "id": "Q91XA9-1", "name": "Acidic mammalian chitinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLLLVTGLALLLNAQL----------GSAYNLICYFTNWAQYRP-------------GLGSFKPDDINPCL--------CTHLIY-AFAGMQNNEITTIEW-NDVTL--------YKAFNDLK--NRNSKLKTLLAIGGWNFGTA---------PFTTMVSTSQNRQTFITSVIKFLRQY-GFDGLDLDWEYPGSRGSPPQ--------------------------DKHLFTVLVKEMREAFEQEAIESNRPRLMVTAAVAGGISNIQAGYEIPELSKYLDFIHVMTYDLHGSWEG--YTGENSPLYKYPTETGSNAYLN----VDYVMNYWKNNGAPAEKLIVGFPEYGHTFILRNPSDNGIGAPTS----GDGPAGPYTRQAGFWAYYEICTFLRS------------GATEVWDASQEVPYAYKAN-------EWLGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQG-----------------------------------------------------KFPLTSTLNKALGISTEGCTAPDVPSEPVTTPP--------------GSGSGGGSSGGSSGGSGFCADKADGLYPVA--------------------DDRNAFWQCINGITYQQHCQAGLVFDTSCNCCNWP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZP6-1", "uniprot_id": "CHIA_HUMAN", "id": "Q9BZP6-1", "name": "Acidic mammalian chitinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKLILLTGLVLILNLQL----------GSAYQLTCYFTNWAQYRP-------------GLGRFMPDNIDPCL--------CTHLIY-AFAGRQNNEITTIEW-NDVTL--------YQAFNGLK--NKNSQLKTLLAIGGWNFGTA---------PFTAMVSTPENRQTFITSVIKFLRQY-EFDGLDFDWEYPGSRGSPPQ--------------------------DKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEG--YTGENSPLYKYPTDTGSNAYLN----VDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTS----GAGPAGPYAKESGIWAYYEICTFLKN------------GATQGWDAPQEVPYAYQGN-------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQG-----------------------------------------------------KFPLISTLKKALGLQSASCTAPAQPIEPITAAPSG-----------SGNGSGSSSSGGSSGGSGFCAVRANGLYPVA--------------------NNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35744-1", "uniprot_id": "CHIL3_MOUSE", "id": "O35744-1", "name": "Chitinase-like protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILVTGLAILLNVQL----------GSSYQLMCYYTSWAKDRP-------------IEGSFKPGNIDPCL--------CTHLIY-AFAGMQNNEITYTHE-QDLRD--------YEALNGLK--DKNTELKTLLAIGGWKFGPA---------PFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQYPGSRGSPPK--------------------------DKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDG--YTGENSPLYKSPYDIGKSADLN----VDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTI----STGPPGKYTDESGLLAYYEVCTFLNE------------GATEVWDAPQEVPYAYQGN-------EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-----------------------------------------------------HFPLTSTLKGDLNIHSASCKGPY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Z98-1", "uniprot_id": "CHIL4_MOUSE", "id": "Q91Z98-1", "name": "Chitinase-like protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILVTGLAILLNVQL----------GSSYQLMCYYTSWAKDRP-------------TEGSFKPGNIDPCL--------CTHLIY-AFAGMKNNEITYLSE-QDLRD--------YEALNGLK--DRNTELKTLLAIGGWKFGPA---------PFSSMVSTPQNRQTFIKSVIRFLRQY-NFDGLNLDWQYPGSRGSPPK--------------------------DKHLFSVLVQEMRKAFEEESTLNHIPRLLLTSTGAGFIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKNG--YTGENSPLYKSPYDIGKSADLN----VDSIITYWKDHGAASEKLIVGFPAYGHTFILSDPSKNGIGDPTV----SAGPPGKYTNEQGLLAYFEICTFLNE------------GATEIFDATQEVPYAYLGN-------EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQG-----------------------------------------------------RFPLTTTLKRDLNVHSASCKASYRGEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M559-1", "uniprot_id": "F1M559_RAT", "id": "F1M559-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILATGLAILLYAHL----------GSSYQLMCYYTSWAKDRP-------------TVGSFKIGNIDPCL--------CTHLIY-AFAGMRNNEIINTSE-QDLID--------YEAINYLK--DRNTELKTLLAIGGWKFGSA---------PFSAMVSTPQNRQTFIKSVIKFLRQY-KFDGLNLDWQYPGSRGSPPK--------------------------DKHLFSVLVQEMRKAFEKESTEQEIPRLLLTATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNG--YTRENSPLYQSPSDTGIYAYLN----VDAIISYWKDNGAAREKLIVGFPAYGHNFILSDPSNTGINAPIV----STGPPGKFTGEAGLWAYYEICTFLND------------GATDLWDGPQEVPYAVQGN-------VWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQG-----------------------------------------------------RFPLTSTLKHYLGVQSTNCMA-YKEEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JDS2-1", "uniprot_id": "A0A0G2JDS2_MOUSE", "id": "A0A0G2JDS2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKLILVTGLALLLNPQL----------GSAYQLMCYYNNVAQNRP-------------KLGSFNPADIDPCL--------CTHLIY-AFAGMQNNKVTMRSM-NDLTD--------YQALNTLK--SRNVQLKTLLAIGGRDFGPA---------PFSAMVSTPHNQQTFINSAIKFLRQY-GFDGLNLDWQFPGSRGSPSR--------------------------DKHLFTVLVQKIREAFELEAIENKSPRLMVTATVAGVISTIQSGYEIPQLSHFLDYIQVMTYNLHGSQDG--YTGENSPLYKSLNDTGINTLLN----VDYIMTYWNENGAAPEKLIVGFPAYGQTFTLSDPSNNGISAPTA----SAGTLGPYTEESGTWAYYEICSFLND------------GATEAWDSAQEVPYAYQGN-------KWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCNQG-----------------------------------------------------QFPLTSTLKNALLVYSTSCMASVSDLQQVNAPLY--------------SGNRNWKRGSKA---------MDSVSPVP--------------------RE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2D4-1", "uniprot_id": "D4A2D4_RAT", "id": "D4A2D4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYKTSEDPAGSVLRAFISKLVFIMGLNLLLNVQL----------DSAYQLMCYFNNWPQYQP-------------DVRGMKLDDIDPCL--------CTHLIY-SFAGIWENNNTMTKR-KDLDD--------YKEFNDLK--KRNNKLKTLLSIGCWNFEAG---------LFITMVSTPESRHTFITSVRKFLRKY-GFDGLNLAWQYPGCYGSPPK--------------------------DKHLFTILTQEIRKAFEKEVSKNKKSRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDG--YTGENSPLYKSPAETGVKAFYN----IKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAPSN----RGGHPGPYTKKTGFWAYYEICAFLKN------------GAIQVWNAAQQVPYAFHGN-------EWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQG-----------------------------------------------------PFPLTSTLKNALKVHSASCKVTALSAN--------------------VTGSRDSN-----------FGALEPLFQLS--------------------SK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36222-1", "uniprot_id": "CH3L1_HUMAN", "id": "P36222-1", "name": "Chitinase-3-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVKASQTGFVVLVLLQC----------CSAYKLVCYYTSWSQYRE-------------GDGSCFPDALDRFL--------CTHIIY-SFANIS-NDHIDTWEWNDVTL--------YGMLNTLK--NRNPNLKTLLSVGGWNFGSQ---------RFSKIASNTQSRRTFIKSVPPFLRTH-GFDGLDLAWLYPGRR-------------------------------DKQHFTTLIKEMKAEFIKEAQ-PGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRG--TTGHHSPLFRGQEDASPDRFSN----TDYAVGYMLRLGAPASKLVMGIPTFGRSFTLAS-SETGVGAPIS----GPGIPGRFTKEAGTLAYYEICDFLRG------------ATVHRILG-QQVPYATKGN-------QWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDL----------------------------------------------------RFPLTNAIKDALAAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTV1-1", "uniprot_id": "CH3L1_RAT", "id": "Q9WTV1-1", "name": "Chitinase-3-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLQLPGFAVLMLLQS----------CSAYKLVCYYTNWSQYRE-------------GNGSCFPDALDHSL--------CTHIIY-SFANIS-NNKLSTSEWNDVTL--------YGMLNTLK--TRNPRLKTLLSVGGWSFGSE---------RFSRIVSNAKSRKTFVQSVAPFLRTY-GFDGLDLAWLYPGPK-------------------------------DKQHFTTLIKELKAEFTKEVQ-PGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRH--TTGHHSPLFRGQQDTGPDRFSN----VDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLAS-SENQVGAPIT----GSGLPGRYTKEKGTLAYYEICDFLRG------------AEVHRILG-QQVPFATKGN-------QWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNV----------------------------------------------------HFPLTNAIKEALAVA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61362-1", "uniprot_id": "CH3L1_MOUSE", "id": "Q61362-1", "name": "Chitinase-3-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHTSTEARMGMRAALTGFAVLMLLQS----------CSAYKLVCYFTSWSQYRE-------------GVGSFLPDAIQPFL--------CTHIIY-SFANISSDNMLSTWEWNDESN--------YDKLNKLK--TRNTNLKTLLSVGGWKFGEK---------RFSEIASNTERRTAFVRSVAPFLRSY-GFDGLDLAWLYPRLR-------------------------------DKQYFSTLIKELNAEFTKEVQ-PGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQ--ITGHHSPLFQGQKDTRFDRYSN----VNYAVQYMIRLGAQASKLLMGIPTFGKSFTLAS-SENQLGAPIS----GEGLPGRFTKEAGTLAYYEICDFLKG------------AEVHRLSN-EKVPFATKGN-------QWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQG-TCQPKE----------------------------------------------------FFPLTNAIKDALA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62010-1", "uniprot_id": "OVGP1_MOUSE", "id": "Q62010-1", "name": "Oviduct-specific glycoprotein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRLLLLAGLVLLMKHSD----------GTAYKLVCYFTNWAHSRP-------------GPASIMPHDLDPFL--------CTHLIF-AFASMSNNQIVAKNLQDENVL--------YPEFNKLK--ERNRELKTLLSIGGWNFGTS---------RFTAMLSTLANREKFIDSVISFLRIH-GFDGLDLFFLYPGLRGSPPH--------------------------DRWNFLFLIEELQFAFEREALLTQHPRLLLSAAVSGIPSIIHTSYDALLLGRRLDFINVLSYDLHGSWEK--FTGHNSPLFSLPEDSKSS---------AYAMNYWRKLGTPADKLIMGFPTYGRNFYLLKESKNGLQTASM----GPASPGKYTKQAGFLAYYEVCSFVQR------------AKKHWIDY-QYVPYAFKGK-------EWLGYDDTISFSYKAMYVKREHFGGAMVWTLDMDDVRGTFCGNG-----------------------------------------------------PFPLVHILNELLVQTESNSTPLPQFWFTSSVNASGPGSENTALTEVLTTDTIKILPPGGEAMTTEVHRRYENMTTVP--------------------SDGSVTPG-GTASPRKHAVTPENNTMAAEAKTMSTLDFFSKTTTGVSKTTT-----------------------------GISKTTTG-VSKTTTGVSKATAGISKTIPEISKAT------AGVSKTTTGVSKTTTGISKTITGVSKTTTGISKTTTGISKTTTGVSKITTGVSKTTTGISKTTTGISQTTTGISKTTTDISKTTTGISKTTPGISKTTPGMTVIVQTQANEAETTATMDHQSVTPTEMDTTLFYLKTMTPSEKETSRKKTMVLEKATVSPREMSATPNGQSKTLKWA-SLITEVETYSQDG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12889-1", "uniprot_id": "OVGP1_HUMAN", "id": "Q12889-1", "name": "Oviduct-specific glycoprotein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWKLLLWVGLVLVLKHHD----------GAAHKLVCYFTNWAHSRP-------------GPASILPHDLDPFL--------CTHLIF-AFASMNNNQIVAKDLQDEKIL--------YPEFNKLK--ERNRELKTLLSIGGWNFGTS---------RFTTMLSTFANREKFIASVISLLRTH-DFDGLDLFFLYPGLRGSPMH--------------------------DRWTFLFLIEELLFAFRKEALLTMRPRLLLSAAVSGVPHIVQTSYDVRFLGRLLDFINVLSYDLHGSWER--FTGHNSPLFSLPEDPKSS---------AYAMNYWRKLGAPSEKLIMGIPTYGRTFRLLKASKNGLQARAI----GPASPGKYTKQEGFLAYFEICSFVWG------------AKKHWIDY-QYVPYANKGK-------EWVGYDNAISFSYKAWFIRREHFGGAMVWTLDMDDVRGTFCGTG-----------------------------------------------------PFPLVYVLNDILVRAEFSSTSLPQFWLSSAVNSSSTDPERLAVTTAWTTDS-KILPPGGEAGVTEIHGKCENMTITP--------------------RGTTVTPTKETVSLGKHTVALGEKTEITGAMTMTSVGHQSMTPGEKALTPV-----------------------------GHQSVTTGQKTLTSVGYQSVTPGEKTLTPVGHQSV------TPVSHQSVSPGGT------TMTPVHFQTETLRQNTVAPRRKAVAREKVTV----PSRNISVTPEGQTMPLRGE-NLTSEVG--------THPRMGNLG---------LQMEAENRMMLSSSPVIQLPEQTPLAFDNRFVP----------IYGNHSSVN----SVTP--QTSPLSLK-KEIPENSAVDEEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15782-4", "uniprot_id": "CH3L2_HUMAN", "id": "Q15782-4", "name": "Chitinase-3-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGATTMDQKSLWAGVVVLLLLQG----------GSAYKLVCYFTNWSQDRQ-------------EPGKFTPENIDPFL--------CSHLIY-SFASIENNKVIIKDK-SEVML--------YQTINSLK--TKNPKLKILLSIGGYLFGSK---------GFHPMVDSSTSRLEFINSIILFLRNH-NFDGLDVSWIYPDQK-------------------------------ENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYN----VEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETT-VGAPAS----GPGAAGPITESSGFLAYYEICQFLKG------------AKITRLQD-QQVPYAVKGN-------QWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQG-----------------------------------------------------PYPLVQAVKRSLGSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7Q1-1", "uniprot_id": "CHIT1_MOUSE", "id": "Q9D7Q1-1", "name": "Chitotriosidase-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQSLAWAGVMTLLMVQW----------GSAAKLVCYLTNWSQYRT-------------EAVRFFPRDVDPNL--------CTHVIF-AFAGMDNHQLSTVEH-NDELL--------YQELNSLK--TKNPKLKTLLAVGGWTFGTQ---------KFTDMVATASNRQTFVKSALSFLRTQ-GFDGLDLDWEFPGGRGSPTV--------------------------DKERFTALIQDLAKAFQEEAQSSGKERLLLTAAVPSDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLEK--TTGHNSPLYKRQGESGAAAEQN----VDAAVTLWLQKGTPASKLILGMPTYGRSFTLASSSDNGVGAPAT----GPGAPGPYTKDKGVLAYYEACSWK---------------ERHRIED-QKVPYAFQDN-------QWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQG-----------------------------------------------------PYPLIRTLRQELNLPSETPR-SPEQIIPEPRPSSMPEQG----------------PSPGLD--NFCQGKADGVYPNP--------------------GDESTYYNCGGGRLFQQSCPPGLVFRASCKCCTWS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13231-1", "uniprot_id": "CHIT1_HUMAN", "id": "Q13231-1", "name": "Chitotriosidase-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRSVAWAGFMVLLMIPW----------GSAAKLVCYFTNWAQYRQ-------------GEARFLPKDLDPSL--------CTHLIY-AFAGMTNHQLSTTEW-NDETL--------YQEFNGLK--KMNPKLKTLLAIGGWNFGTQ---------KFTDMVATANNRQTFVNSAIRFLRKY-SFDGLDLDWEYPGSQGSPAV--------------------------DKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEK--VTGHNSPLYKRQEESGAAASLN----VDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPAT----GSGTPGPFTKEGGMLAYYEVCSWKG-------------ATKQRIQD-QKVPYIFRDN-------QWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-----------------------------------------------------RYPLIQTLRQELSLPYLPSG-TPELEVPKPGQPSEPEHG----------------PSPGQD--TFCQGKADGLYPNP--------------------RERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GSW9-1", "uniprot_id": "A0AC58GSW9_DANRE", "id": "A0AC58GSW9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIWTCSSNKMNRGITHLIGLNLLFQF----------VACSKLVCYFTNWSQYRS-------------GTARYLPENVDPNL--------CTHLIY-AFAIINYANNIAGSEWNDVVH--------YSTFNALK--KRNPQLITLLSVR--DQDSS---------QFSIMLSKWINRQTFIKSSIEFLRKY-NFDGLDLDWEMKNTSEMHPE--------------------------DKLKFTLLCKELLEAFVAESL-NSDTRLILTATVSAQKDVIERSYIIPEISEYLDFINVKTFDFHTYKDG--IARHHSALYSAMSD-DKDIKSN----TDFALQYWRSQGAPAEKLLMGFSTYGRSFILNS-SQNGVGAPAN----KFASPGPHTQEIGLWAYYEICLFLNG------------GVVQWIED-QKVPFSVKGN-------DWVGFDSLRSFNIKTKYLLEHGFGGAFVWALDLDDFSGYFCGQG-----------------------------------------------------TYPLVNSLKKSLIHGIESSSSMTSTNFFFSIFATAGKGS------LPTPICVKIVRSFSAQQSLFCANRSDGLYYRT--------------------NSLNSFYSCSEGITNITWCTPFHAISNNSRKVQLSLMIIFITLGSAGFLTK-----------------------------MLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZV2-1", "uniprot_id": "Q9VZV2_DROME", "id": "Q9VZV2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRV-------------KIGKFVPEDIPADL--------CTHIIF-AFGWLKKNKLSSYESNDETKDNV---PGLYERMMTLK--KANPKLKILLALGGWSFGTQ---------KFKDMSSTRYTRQTFVYSAIPFLRKR-GFDGLDMDWEYPKGSD------------------------------DKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWER--ETGHNAPLYAPSTDSEWRKQLS----VDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPAS----GGGREGVYTKEGGFLAYYEICEMLLN------------GAVYVWDDEMKVPYLVDGD-------QWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNV----------------------------------------------------KYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEK-PEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNT--------------------RPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNG------LDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNT-TLVWDSEQQVPFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDYKVELEYDGPYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M6-1", "uniprot_id": "Q9W2M6_DROME", "id": "Q9W2M6-1", "name": "chitinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLVSIWALAALCLCLGQVAS----------SEKLLNCYWGTWANYRP-------------GDGKFTPSDIDPSL--------CTHISY-TFFGIS-DAGEFKSLDTWLDMDD--GLGFISQTIALK--QRNPNLKILAVVGGWNEGST---------KYSAMAADPAKRATFVSTSLAFIQQY-SFDGLDLDWEYPGQRGGSEA--------------------------DRENFVTLLREIKETYD-----QYGLELGIAVG--ASEKSASISYDIPAISQHLTFINVMTYDFHMALDG--YLGLNAPLPEVAESID----------------YWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACI----GPGTAGVYTRENGFLGYHEICLNN---------------WQTVFDQENGAPYAFQGD-------QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCG-------------------------------------------------------ESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDGFFVLESD-----------------------------CNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKLLALLAV-LCLSQVIG----------AERIVNCYWGTWANYRS-------------GNGKFDVSNIDAGL--------CTHLSY-SFFGIN-DNGEIQSLDTWLDYD----LGFINQAISLK--NQNSNLKVLAVVGGWNEGST---------KYSSMSGDWYKRQNFINSALNLLRNH-GFDGLDLDWEYPNQRGGNWN--------------------------DRANFVTLLREIKEAFA-----PYGYELGIAVG--AGESLASASYEIANIAQQVDFINVMTYDFAMASDG--QTGFNAPQWAVENAIN----------------FWLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCR----GEGSAGSYTGSTGYLGYNEICQNN---------------WHTVFDYDNAAPYAYSGD-------QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG-------------------------------------------------------ETYPLLKTINRKLRW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M7-1", "uniprot_id": "Q9W2M7_DROME", "id": "Q9W2M7-1", "name": "chitinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWSVSGLVKLLLGVILMAASSSAQGN---------SSKNVVCYQGTWSVYRP-------------GLGKFGMEDIDPFL--------CTHLIY-AFLGIE-ETGQLRVIDAYLDLEENSGRGNIKSFNALK--LKNPVLKTLVAVGGWNEGSK---------RFSLVARDPSKREKFVDDVVRFLQRH-GFDGLDLDWEYPGQRHSLDNE-------------------------DRSNYITFLKELKEGLE-----PFGFILSAAVG--SAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQ--VVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHI----GKGIAGNYSREPGVLGYNELCEMMERE---------E--WTQKWEATQQVPYAYRQR-------QWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQ------------------------------------------------------QPYPLLHEINRVLFG--------------------GNTPSGLTTESNRESPSEGFSCPADAPAGYIRDPDN-----------------------------CSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLW8-1", "uniprot_id": "Q8MLW8_DROME", "id": "Q8MLW8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSFQYVFMIMIFLICGCIA---------KEYNVFCQYDLGSYYYK-------------GRSQFFEWHLDSRL--------CTHLVLGSGIGVDGDSGELRITDKILLLEK----DKLSSVKTMK--WDS-IKKVMFTIGGWEEDSS---------SFSRMVASPKKRDNFYSSMLEFMFRW-GFDGVQIDWRYPTLLGGHPD--------------------------DRQNFVILLEELGLIFR-----KNQLILMVAVLG-RRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHL--RLAYNAPLVGYEGSVTDS------------IMHWKRNGGAPEKLILGIPLFVRSFTMD-RNQSTVGSACK----GPGRQTKQSHRPGFMTYNEWCVQQSK-------------WSRMFDQLAKVPYATRGD-------QWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCG-------------------------------------------------------EQHGLLRVIFSALGD-----------------------KNGLTTEKPTTEASG-----LCPHDGFSRDGWD-----------------------------CRLYHECRDGERIYYECLEGQYFDENQIVCRPAAEVKCDQNFVIWRPGMPVYSYDNMPLNLKIVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFR3-1", "uniprot_id": "Q9VFR3_DROME", "id": "Q9VFR3-1", "name": "chitinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRYIPLLLLGVLCSWPAATVASD---------QASRIVCYFSNWAVYRT-------------GIGRYGLEDVPADL--------CTHIIY-SFIGVNDKSWDVLVIDPELDVDQ----GGFSKFTQLK--KSNPNVKLEIAVGGWAEGGS---------KYSQMVAVRDRRQSFIRSVVRFMKQY-NFDGFDLDWEYPGATDRGGNYG------------------------DKDKFLYFVEELRRAFD-----REGRGWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAG--FADVHSPLYKRKHDQYAYEKLN----VNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDK---------SKGWTVEWDDAGMVPYTYKDT-------QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "id": "Q9W092-1", "name": "Probable chitinase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTG----PLHDKVVVCYVSTWAVYRP-------------EQGAYAIENFDPNL--------CTHVVY-AFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLK--RSHPHLKVSLAIGGWNEGSA---------NYSTLVANNLLRGRFVKQVSSFIRKY-NFDGLDLDWEYPTQRKGKPA--------------------------DRENFVLLTKELREEFD-------EHGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDR--RVGYNAPLTAPADDPLS---------VKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDVSEGV------GFKGPYTREDGFLGYNEICQTLSNQ---------TSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDED----------------------------------------------------TYEDFQKVTAAPKRSSQNYPLLR------------------------TINEATMLAVDELAVPEPQPDDSENEIPHG----------------------SIADRKNAGASMVSLGLGVTAVFMLLHRLAQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5U2-1", "uniprot_id": "CHI10_DROME", "id": "Q9W5U2-1", "name": "Probable chitinase 10", "aln": "MHPYVPSVLVVVVLAISVKAHIRVDKLQIHSESNYKPAFIRSAVESIPLDIDAILLLRNSTKPEFGDAFLPLRSAVESIPKLYQSNTSRFRKNPDVRSFVRDSVESLPNDEDGLEHIEIFTKYYNSVSDVAGVDLKSKKLTHVNLDPGTISDKYAAFIARGNSEDYYPKSYRAGSPHQELLKMMNIEHTDKLDRYSDLQHQQSYGALGLANRNDLKMTKKVLCYMSNWAFYRSGEAHFVPEQIDPNLCSAIIYSFASLDPDHLTIREFDSWVDLDNQYYRRVTSLGVPVLIALGGWTDSSGSKYSRLVSDNLKRRVFISSVSSFLLRHGFSGLHLDWNYPKCWQSDCSRGPVTDRPNLTKLLRELRTEFQSVDPKFQLGVAISGYKEIIKEAYDFPALSDIVDYMTVMTYDYHGAWEQKTGHVSPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLSIPFYGQSFTLATAHQILAGPGVAASGPGDAGELTKQPGMLAYYEICQRLTKFNWISDRNLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAINRALGRLDSEPPTQPNCKRPTLLATPVPPQMTTISSDGSGGLGQNHDHTTSLPSGQISSSPVSTTITSTFPWWSSTTKRPREPTKTTAQPTHTTILIPAGINPVVQPSNCKSGEFFADSNNCNAYYHCFFAGELQQQFCPSGLHWNNEAKGCDWPSSAQCSLKLDQHLSTSYPNPIQTSKKPETTLKPNKKPSEISTHHQVNSTSSRPQYMRPTILECTEGDYYPHRNCRKYYICVNKALVPSECGGDLHWDGIKKLCDWPENVQCVTSKKYLKIIKSSSANEEDPCKGEKRVPYPGNCSKYLFCLWNRLQASDCPPGLHYNERIGNCDWPAAAKCNPKGSESSEEAELNAMPKPPTPQTPSSHLRPTYPTEKPVPKPRDSHYKVICYFTNWAWYRK-------------GIGRFTPDDINTEL--------CTHVIY-GFAVLDYSELVLRTHDSWADVEN----NFYTRVTSLK--SKG--IKVSLALGGWNDSQGD--------KYSRLVRSPMARSRFVRHALEFIEKY-GFEGLDLDWEYPVCWQTECNKGS---------------------TEEKDGFTAWVQELSEAFR-------PRGLMLSTAVSPSRKIIDAGYDIPQLSRYFDWIAVMTYDFHGHWDK--KTGHVAPLYHHPDDDFEYFNVN------YSINYWMEKGAPSQKLVMGIPLYGQSFTLENTNSSGLNAKAP----APGEAGEFTRAAGFLAYYEICERVNRQ---------G-WQVVHDEFGRMGPYAYKGT-------QWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNRCGNG------------------------------------------------------VHPLLTEIHNVLKDPPSLMEIPGPIETTPTEYPGMEEEIHESNGEGPEVQPIEAVMQTCENEGEEHEGILDPNHVLE----------EENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQPRGLILSAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKKTGHVAPMYSHP---EGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNVCECESYPLLKAINRVLRGFGGPQPKCLLENPKSTMKPNIKPPFRPTINAPSGPNLDSPTQNVSLNVLSIKCHSKNYLAHEWDCTKYYICEHGTYVERSCPLGLQWNKTYCDWPTNVQSSLGSNQRTQEPAVHRPNPTSVITEPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENGLILSAAVSPSKMVIDAGYNVFELSPYFDWVAVMTYDFHGHWDMRTGQIAPLFHRGGDENLYLNGNFSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEGIFGSYAYSGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRGLCGCGKHPLLRTLSQELLGIPGQKAKDCI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W303-1", "uniprot_id": "IDGF4_DROME", "id": "Q9W303-1", "name": "Chitinase-like protein Idgf4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLYALFSLLVGSLAIGQISAAGS------------HHLLCYYDGNSFVRE-------------GLSKLILTDLEPALQ------YCTHLVY-GYAGINPSSNKLVSNNEKLDLDLG--SSLFRQVTGLK--RKYPALKVLLSVGGDKDTVDPEN-----NKYLTLLESSNARIPFINSAHSLVKTY-GFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFR-------PDGYILGLSVLPNVN-SSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAPIYELNERNPEFN-------VNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEAD-GVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTG-----------------------------------------------------HDKFPILRQVKSKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23997-1", "uniprot_id": "C5210_DROME", "id": "Q23997-1", "name": "Imaginal disk growth factor 6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIIKALAIVSLCLASIQASKVGAPQLP----------KKHLVCYYDSASFVKE-------------GLGKLVIDELEPALQ------FCDYLVY-GYAGIERDSHKAVSLNQQLDLDLG--KGLYRTVTRLK--RKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTY-GFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFR-------PDNLLLSTTVLPNVN-SSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSERNPEFN-------VAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVK-DEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCT------------------------------------------------------NEKYPILRAIKYRLTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3V1-1", "uniprot_id": "Q9W3V1_DROME", "id": "Q9W3V1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNYEKLDGSSAGRITDELSRKEQRNCSLRTLVCWSALLFSLLCLCLGFIGLGLLGIQTGEVHKVGQRLVCYYA-------------SDGTHNLSLLDVPGD------LCTHINI-GPATLDNATIVLPDTLRQVLQN---------DTRSFR--AAHPQVHLLLWIGGADSGRS----------FALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPSAYDR-----------------------------ERMHLSQLLYEIRTEWRR----EKRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFN----INYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPAS----GYGKCG----QLGFTTLTETCECVTK----------FFKPNLSYDAESCSPYLSALQ-------EWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPN---------------------------------------------LKYSEKPVFPLTQAIKDILRESL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHG----THIRDEAFISGVYYSNWSPYKPRFHFPHDINLKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSDSEN----------FKIIIKDDKLLQNFVDSSVETMFRL-GFDGIDLDWEFPGNNESEPR--------------------------GYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSET--TGYHSNLFSETELNGNFAMHY----------MIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLP--------KIGTIEQYDPKYVSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESR----------------------------------------------------------SLINAFNEGLHFNVSSKP--------------------------------------------------------------------------------SIFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : : : * : ::*.:. : : .: : :: :*. : : : . * : ::. * .* : . ", "identical_positions": 6, "similar_positions": 33, "identity": "0.24%" }, { "cls_id": "homologset.agr.SGD:S000002780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERE4-1", "uniprot_id": "GOLP3_RAT", "id": "Q9ERE4-1", "name": "Golgi phosphoprotein 3", "aln": "MTSLT----QRSSGLVQRRTEASRNAADKERAAGGGGGNGEDEAQSRRDEQDDDDK---GDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRK-SLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL------------------------DLDPEVECLKAN--TNEVLWAVVAAFTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRA5-1", "uniprot_id": "GOLP3_MOUSE", "id": "Q9CRA5-1", "name": "Golgi phosphoprotein 3", "aln": "MTSLT----QRSSGLVQRRTEASRNAADKERAAGGGGGSGEDEAQSRRDEQDDDDK---GDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRK-SLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL------------------------DLDPEVECLKAN--TNEVLWAVVAAFTK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4A6-1", "uniprot_id": "GOLP3_HUMAN", "id": "Q9H4A6-1", "name": "Golgi phosphoprotein 3", "aln": "MTSLT----QRSSGLVQRRTEASRNAADKERAAGGGAGSSEDDAQSRRDEQDDDDK---GDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRK-SLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDRRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL------------------------DLDPEVECLKAN--TNEVLWAVVAAFTK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ93-1", "uniprot_id": "GOLP3_DROME", "id": "Q9VQ93-1", "name": "Golgi phosphoprotein 3 homolog sauron", "aln": "----M----NRSDGLVRRSVKPRENGGAEGGLNANTPDDNQDALDNLKDQEDNIDD---GDSKETRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRVMIEKSGMRRR-GLCTRKLILKSDQQTGDVLLDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLSDNVVKCRLVKKIQDSVLSK---------WVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYEVAMKRVRELL------------------------DLDFEAESAKPN--ANEILWAVFMAFTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R088-1", "uniprot_id": "GLP3L_MOUSE", "id": "Q8R088-1", "name": "Golgi phosphoprotein 3-like", "aln": "MTTLT----HRT-----RRTEVSKSSEKK-------IESEED--TNQERSPDNEDP---GDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKK-RLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLMKKLQDSVLER---------WVNDPQRMDRRTLALLVLAHSSDVLENVFSCLTDDKYDVAMNRTKDLV------------------------ELDPEVEGTKHN--ATEMIWAVLAAFNKS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H74-1", "uniprot_id": "GLP3L_RAT", "id": "Q66H74-1", "name": "Golgi phosphoprotein 3-like", "aln": "MTTLT----HRT-----RRTEVSKSCEKK-------IESEED--TNQERSPDNEDP---GDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKK-RLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLMKKLQDSVLER---------WVNDPQRMDRRTLALLVLAHSSDVLENVFSCLTDDKYDVAMNRTKDLV------------------------ELDPEVEGTKHN--ATEMIWAVLAAFNKS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4A5-1", "uniprot_id": "GLP3L_HUMAN", "id": "Q9H4A5-1", "name": "Golgi phosphoprotein 3-like", "aln": "MTTLT----HRA-----RRTEISKNSEKK-------MESEED--SNWEKSPDNEDS---GDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKK-RLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLER---------WVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRAKDLV------------------------ELDPEVEGTKPS--ATEMIWAVLAAFNKS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N848-1", "uniprot_id": "A0A8M1N848_DANRE", "id": "A0A8M1N848-1", "name": "", "aln": "MTTLT----KRN-----RRSEPPAERWSN-------AEEEEE---KKREEEEEEED---TDCKTLRLTLMEEILLLGLKDKEGYTSFWNDSISSGLRSCMLVELGLRGRIQLEPQGTRRR-KLLERKVLLKSAAPTGDVLLDEALKHIKNTEPAENMASWIELLTGETWNPMKMHFQMRNVRERLAKSLVEKGVLTTEKQNFLLFDMTTHPLTDRTEKERLLQRVQDSLLDR---------WTNDSRRISHRMLALLLLAHVSDVLENALSSLPDECYELASTRSRTLL------------------------EADPDQESSRVSSPAEEIVWAILAAFNKS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06385-1", "uniprot_id": "VPS74_YEAST", "id": "Q06385-1", "name": "Vacuolar protein sorting-associated protein 74", "aln": "MSTLQRRRVNRADSGDTSSIHSSANNTKGDKIANIAVDGDDDNGTNKKIAYDPEESKLRDNINIPTLTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFDLSERLIEVIDSSKTGEVLLDETLQLMKNDEP-LSISNWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPIADASCKEAIKRRVLSVLVSRNMELSYNEYFPETTSFKIIRTLALICGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKETELGVSVNLNKEVKEEIENNPGHDLQLEVIAGVFEVFSRMDMLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :: . . : : : : ******:**:**:*:*** *****.** .**. :::**.:**:: : *:: * * : . **:*****:*: :* :* .: .**: *:***** :*:.:*:::****:**.**:**:* ** :**:****:***::: * : ::: . ::.: : : . * ***: :: ::*:**.:: * : : * .* . :: : . : * *:: .:. .*.: ", "identical_positions": 87, "similar_positions": 95, "identity": "25.14%" }, { "cls_id": "homologset.agr.SGD:S000002781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84076-1", "uniprot_id": "HPCA_RAT", "id": "P84076-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84074-1", "uniprot_id": "HPCA_HUMAN", "id": "P84074-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84075-1", "uniprot_id": "HPCA_MOUSE", "id": "P84075-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62748-1", "uniprot_id": "HPCL1_MOUSE", "id": "P62748-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62749-1", "uniprot_id": "HPCL1_RAT", "id": "P62749-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37235-1", "uniprot_id": "HPCL1_HUMAN", "id": "P37235-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61601-1", "uniprot_id": "NCALD_HUMAN", "id": "P61601-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQN0-1", "uniprot_id": "NCALD_RAT", "id": "Q5PQN0-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X97-1", "uniprot_id": "NCALD_MOUSE", "id": "Q91X97-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JTH1-1", "uniprot_id": "NCLDA_DANRE", "id": "A9JTH1-1", "name": "Neurocalcin-delta A", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGNLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIKGAKTDPSIVRLLQCDPSSAGQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AXL4-1", "uniprot_id": "NCLDB_DANRE", "id": "Q6AXL4-1", "name": "Neurocalcin-delta B", "aln": "MGKQNSKLRPEVIQDLLDNTDFTEHEILEWYKGFLRDCPSGALSMDEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGRLDQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSS--VMKMPEDESTPEKRTDKIFRQMDTNRDGKLSLEEFVEGAKNDPSIVRLLQCDPSSAGQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42325-1", "uniprot_id": "NCAH_DROME", "id": "P42325-1", "name": "Neurocalcin homolog", "aln": "MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGS--VMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62761-1", "uniprot_id": "VISL1_MOUSE", "id": "P62761-1", "name": "Visinin-like protein 1", "aln": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62760-1", "uniprot_id": "VISL1_HUMAN", "id": "P62760-1", "name": "Visinin-like protein 1", "aln": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62762-1", "uniprot_id": "VISL1_RAT", "id": "P62762-1", "name": "Visinin-like protein 1", "aln": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TZ35-1", "uniprot_id": "Q5TZ35_DANRE", "id": "Q5TZ35-1", "name": "", "aln": "MGKQNSKLTPEVMEDLVKNTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNSDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDRIFSKMDKNNDDQITLDEFKEAAKSDPSIVLLLQCDMQK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BGZ1-1", "uniprot_id": "HPCL4_MOUSE", "id": "Q8BGZ1-1", "name": "Hippocalcin-like protein 4", "aln": "MGKNNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35332-1", "uniprot_id": "HPCL4_RAT", "id": "P35332-1", "name": "Hippocalcin-like protein 4", "aln": "MGKNNSKLAPEELEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UM19-1", "uniprot_id": "HPCL4_HUMAN", "id": "Q9UM19-1", "name": "Hippocalcin-like protein 4", "aln": "MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPW8-1", "uniprot_id": "A3KPW8_DANRE", "id": "A3KPW8-1", "name": "Hippocalcin-like protein 4", "aln": "MGKHNSKLAPEVLDDLTKSTEFNEAELKQWYKGFLKDCPSGILNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRMEMLEIIEAIYKMVGTVIMMRMNEDGLTPQQRVDKIFSKMDKDHNDEISLEEFKEAAKSDPSIVLLLQCDMQK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BNY6-1", "uniprot_id": "NCS1_MOUSE", "id": "Q8BNY6-1", "name": "Neuronal calcium sensor 1", "aln": "MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGN--TVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62166-1", "uniprot_id": "NCS1_HUMAN", "id": "P62166-1", "name": "Neuronal calcium sensor 1", "aln": "MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGN--TVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62168-1", "uniprot_id": "NCS1_RAT", "id": "P62168-1", "name": "Neuronal calcium sensor 1", "aln": "MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGN--TVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37236-1", "uniprot_id": "FRQ1_DROME", "id": "P37236-1", "name": "Frequenin-1", "aln": "MGKKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQ--QPQS-EDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSLGGG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWX8-1", "uniprot_id": "FRQ2_DROME", "id": "Q9VWX8-1", "name": "Frequenin-2", "aln": "MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQ--QPQT-EDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRIVQALSLGGD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06389-1", "uniprot_id": "NCS1_YEAST", "id": "Q06389-1", "name": "Calcium-binding protein NCS-1", "aln": "MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS--MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*** : : * * * *: :*:***::***.* * * ::* :*** *.. .** * .** : :* *.* **: .** **:* :::** *** :**:: :* *: ** *: ::*:*:. :: **: *..:** ** : :. ::*:** ..:* ** *: *. ", "identical_positions": 68, "similar_positions": 53, "identity": "34.87%" }, { "cls_id": "homologset.agr.SGD:S000002782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5A9-1", "uniprot_id": "YTHD2_HUMAN", "id": "Q9Y5A9-1", "name": "YTH domain-containing family protein 2", "aln": "---MSASSLLEQRPKGQGNK---------------------------VQNGSVHQKDGLNDDDFEPYLS-PQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTP-FLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMN--TIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG--IAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGH-NGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YT7-1", "uniprot_id": "YTHD2_MOUSE", "id": "Q91YT7-1", "name": "YTH domain-containing family protein 2", "aln": "---MSASSLLEQRPKGQGNK---------------------------VQNGSVHQKDGLNDDDFEPYLS-PQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTP-FLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMN--TIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG--IAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGH-NGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABJ9-1", "uniprot_id": "A0A8I6ABJ9_RAT", "id": "A0A8I6ABJ9-1", "name": "YTH domain-containing family protein", "aln": "---ARRRPLLSQRPKGQGNK---------------------------VQNGSVHQKDGLNDDDFEPYLS-PQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTP-FLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMN--TIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG--IAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVTQTSVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGH-NGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKNAKRKKKVLKRNVKAVGNKKRFCIDCSNGCVCLS-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7F1H9-1", "uniprot_id": "YTHD2_DANRE", "id": "E7F1H9-1", "name": "YTH domain-containing family protein 2", "aln": "---MSASSLLEQRPKGQANK---------------------------VQNGAVTQKDTLNDDEFEPYLN-AQPRQSNAYTAMSDSYMPSYYSPSIGFTYSLNEAAWSTGGDPPMPYLASYGQLSNGEHHFLPDAMFGQSGALGNNP-FLGQHGFNFFPSGIDFPAWGNSSSQGQSTQSSGYSSSYAYAPSTLGGAMIDGQSPFAANEPLNKAVGMN--SLDQGMAGLKIGAGDMA---PKVVGSGLPGGPLS-QVSTAPTMPPASMAPAKTASWADIASKPAKPQPKLKTKGG--LGGTNLPPPPIKHNMDIGTWDNKGNMPKPAAPQQTSLPTNGQPPNQSSPQPGATAGGVPQLPLSNGQLVPPTGQLVQHPLPPGGQPGAVPPQLSQGPPASQPSQPTRWVPPRNRANGFG--DAAGGPGQSPPNSGMGGITVPAEPHPVLEKLRMVNNYNPKDFDWNPK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSLANKG-PLYLLFSVNGSGHFCGVAEMRSPVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLDKARQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKVEVQGSDPYSNNSSRSHYRMQDRQGRVK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P59326-1", "uniprot_id": "YTHD1_MOUSE", "id": "P59326-1", "name": "YTH domain-containing family protein 1", "aln": "---MSATSVDPQRTKGQDNK---------------------------VQNGSLHQKDAVHDNDFEPYLS-GQSNPSNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNN---IYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQTGFHS-DSLNKAPGMN--SLEQGMVGLKIG--DVTTSAVKTVGSVVNSVALT-GVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGG-ALPPPPIKHNMDIGTWDNKGPAPKASAPQQTPSPQAAPQ-PQQVAQP---------LPVQPPPLVQPQYQSPQQP------------------------LQPRWVAPRNRNAAFGQSGGANSDSNSVGNAQPTSAP-SVESHPVLEKLKAAHSYNPKEFDWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRKERQNRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F2Q6-1", "uniprot_id": "F7F2Q6_RAT", "id": "F7F2Q6-1", "name": "YTH domain-containing family protein", "aln": "---MSATSVDPQRTKGQENKGSGWLWRRVSQLAVDREALPSTLSYSHLQNGSLHQKDAVHDNDFEPYLS-GQSNPSNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNN---IYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQTGFHS-DTLNKAPGMN--SLEQGMVGLKIG--DVTTSAVKTVGSVVNSVALT-GVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGG-TLPPPPIKHNMDIGTWDNKGPAPKASAPQQTPSPQAAPQ-PQQVAQP---------LPVQPPPLVQPQYQSPQQP------------------------LQPRWVAPRNRNAAFGQSGGANSDSNSVGSAQPTSAP-SVESHPVLEKLKAAHSYNPKEFDWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRKERQNRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYJ9-1", "uniprot_id": "YTHD1_HUMAN", "id": "Q9BYJ9-1", "name": "YTH domain-containing family protein 1", "aln": "---MSATSVDTQRTKGQDNK---------------------------VQNGSLHQKDTVHDNDFEPYLT-GQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNN---IYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHS-DTLSKAPGMN--SLEQGMVGLKIG--DVSSSAVKTVGSVVSSVALT-GVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGG-GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQ-PQQVAQP---------LPAQPPALAQPQYQSPQQP------------------------PQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAP-SVESHPVLEKLKAAHSYNPKEFEWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BYK6-1", "uniprot_id": "YTHD3_MOUSE", "id": "Q8BYK6-1", "name": "YTH domain-containing family protein 3", "aln": "---MSATSVD-QRPKGQGNK-------------------------VSVQNGSIHQKDAVNDDDFEPYLS-SQTNQNNSYPPMSDPYMPSYYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQNSAYSSSYGYPPSSLGRAITDGQAGFGN-DTLSKVPGIS--SIEQGMTGLKIGG-DLTAAVTKTVGTALSSSGMT-SIAT-NNVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLV--QSQLPQQQPQPPQPQQQQGPQPQAQ-----------PHQVQSQQPQLQNRWVAPRNRGTGFNQNNGTGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLK-NGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKG-PLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQD-KWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER-NRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z739-1", "uniprot_id": "YTHD3_HUMAN", "id": "Q7Z739-1", "name": "YTH domain-containing family protein 3", "aln": "---MSATSVD-QRPKGQGNK-------------------------VSVQNGSIHQKDAVNDDDFEPYLS-SQTNQSNSYPPMSDPYMPSYYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGN-DTLSKVPGIS--SIEQGMTGLKIGG-DLTAAVTKTVGTALSSSGMT-SIAT-NSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLV--QSQLPQQQPQPPQPQQQQGPQPQAQ-----------PHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLK-NGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKG-PLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQD-KWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER-NRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ACC2-1", "uniprot_id": "A0A8I6ACC2_RAT", "id": "A0A8I6ACC2-1", "name": "YTH domain-containing family protein", "aln": "MFYLDLTLLH-RAEETGEES-------------------------FSVQNGSIHQKDAVNDDDFEPYLS-SQTNQNNSYPPMSDPYMPSYYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQNSAYSSSYGYPPSSLGRAITDGQAGFGN-DTLSKVPGIS--SIEQGMTGLKIGG-DLTAAVTKTVGTALSSSGMT-SIAT-NNVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGSVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLV--QSQLPQQQPQPPQPQQQQGPQPQAQ-----------PHQVQSQQPQLQNRWVAPRNRGTGFNQNNGTGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLK-NGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKG-PLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQD-KWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER-NRNKQ---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VBZ5-1", "uniprot_id": "YTHDF_DROME", "id": "Q9VBZ5-1", "name": "YTH domain-containing family protein", "aln": "--MSGVDQMKIPGNTAKS-----------------------------VEERNIPWSQQVDEASYENLSSPTHDEVSGNDNSMQFQYPPFNFKENCNTPWNN-----MNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKP---AAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLG----YSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGN--------NNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRPATNAGPFG---------------PPNARRHDGGPHPSRN------------------SERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQD-KWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06390-1", "uniprot_id": "MRB1_YEAST", "id": "Q06390-1", "name": "Methylated RNA-binding protein 1", "aln": "------------------------------------------------------MNQIWSTGPPNFYFN----------------------------------SEWKENKRNDRTIEDSLRELDGLIHSLERTHIEVQTNPKLKN----------------DVTALNDINKKENKEEITHENYTHQINSIPLTSSNLNRHFSFSR--DYNQSDNSN------------------------------------------------------NNYYREYLSKPRYLQQSTK-------------------------------------------------------------------------------------------------------------------------------------------------------EQTFNEINKRKSAAIIPPWLNIPENSRFFVIKSSSLKHVKRSFYNGIWSSTHFGNKRLSEAYKKLNSGA-KVFLFFSINTSGRFCGVAEMVSDLKMDLDTSIWEDEQKYGKAFKVRWVIVRDINNRSLKRFLIPSNEMKPITHSRDTQEIPYSIGISIINLFKTQDS-----DIFSFLDETYE------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . . : . . . . ..: :. : . . . : : .: . * . . .::::. :. : .*.*:*** * ..::**: **.**..*****. *:: . : *:**:* **:***:*:* : :. . :.:*.:: *: *.*:*: *:*: * *::: : .*: *.:*:******:* . . .::::: : . . : : ", "identical_positions": 49, "similar_positions": 95, "identity": "6.24%" }, { "cls_id": "homologset.agr.SGD:S000002783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZP5-1", "uniprot_id": "BCS1_MOUSE", "id": "Q9CZP5-1", "name": "Mitochondrial chaperone BCS1", "aln": "-----------------------------------MPFSDFVL-ALKDNPYFGAGFGLVGVGTALAMARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRH-STRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVERNRDMQMVDLQTGTPWESVTFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLA-VENPIKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNYIDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLKATSEISPAQVQGYFMLYKND-PMGAVHNIESLR-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y276-1", "uniprot_id": "BCS1_HUMAN", "id": "Q9Y276-1", "name": "Mitochondrial chaperone BCS1", "aln": "-----------------------------------MPLSDFIL-ALKDNPYFGAGFGLVGVGTALALARKGVQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRH-STRTQHLSVETSYLQHESGRISTKFEFVPSPGNHFIWYRGKWIRVERSREMQMIDLQTGTPWESVTFTALGTDRKVFFNILEEARELALQQEEGKTVMYTAVGSEWRPFGYPRRRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLA-VENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLRATNQISPAQVQGYFMLYKND-PVGAIHNAESLRR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV60-1", "uniprot_id": "BCS1_DANRE", "id": "Q7ZV60-1", "name": "Mitochondrial chaperone BCS1", "aln": "-----------------------------------MTLSDFIG-ALKDNPYFGAGFGLVGVGTALAVARKGAQVGMIFFRRHYMITLEVPSKDKSYHWLLSWITKH-AKHTQHLSVETSYMQHESGKVHTQFDFHPSPGNHIIWYGRKWIRVERVREKQMMDLHTGTPWESVTFTALGRDRQTFFNILQEARELALKQEEGRTVMYTAMGAEWRPFGFPRRRRPLSSVVLESGVAERIVDDVKEFIGNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELGYSICLMSLSDRSLSDDRLNHLLSVAPQQSIILLEDVDAAFVSRELLPTENPLAYQGMGRLTFSGLLNALDGVASSEARIVFMTTNFIERLDPALVRPGRVDLKQYVGHCSHWQLTQMFRRFYPQESAAEADHFSEQALAAHTDLSAAQVQGHFMLYKTD-PAGAIKNIAEIKD----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL22-1", "uniprot_id": "Q9VL22_DROME", "id": "Q9VL22-1", "name": "Mitochondrial chaperone BCS1", "aln": "-----------------------------------MTLPDLVA-GLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLKWITIRGARKTQHLSVETNFVQNDNGTIKTSYDFIPSIGKHLFQYKGNWIQVERTREQQTLDLHMGVPWETVTLTAFGNNKGIYFDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGSVVLDRGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSERGLTDDRLNHLLNVAPEQSIILLEDIDAAFVSREAT-PQQKSAFDGLNRITFSGLLNCLDGVGSTEARIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAEEFGKRVNSFGRSASPAQIQGFFMKHKLSSPQTVIDSCEDIWENVLDHNKKIN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32839-1", "uniprot_id": "BCS1_YEAST", "id": "P32839-1", "name": "Mitochondrial chaperone BCS1", "aln": "MSDKPIDIQYDKQATPNLSGVITPPTNETGNDSVREKLSKLVGDAMSNNPYFAAGGGLMILGTGLAVARSGIIKASRVLYRQMIVDLEIQSKDKSYAWFLTWMAKHPQRVSRHLSVRTNYIQHDNGSVSTKFSLVPGPGNHWIRYKGAFILIKRERSAKMIDIANGSPFETVTLTTLYRDKHLFDDILNEAKDIALKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGILDDVYDFMKNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSENNLTDDRLNHLMNNMPERSILLLEDIDAAFNKRSQT---GEQGFHSS--VTFSGLLNALDGVTSSEETITFMTTNHPEKLDAAIMRPGRIDYKVFVGNATPYQVEKMFMKFYPG-ETDICKKFVNSVKELDITVSTAQLQGLFVMNKDA-PHDALKMVSSLRN----ANHIF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:: .:..****.** **. :*:. *: *.* . : *: :: **: .:*:** *:*.*:: : ::****.*.::*::.* : *.:.: *. *:* : * :* ::* *. : :*: * *:*:**:*:: :: : :**:**: :**: **:**:**:.*.*** ** *: :* **:*: * : *: * :*: . ** :****************.**:*** ****** :.:*::.*:: .*:*******:. *::*::****:**** .*. :.. :*******.**** *:* *.*****. ::**.*::****:* * ::* .: :*: :** .*:. . ...* : . *.**:** *: * * .:. .: ", "identical_positions": 162, "similar_positions": 141, "identity": "34.62%" }, { "cls_id": "homologset.agr.SGD:S000002784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56522-1", "uniprot_id": "ADRO_RAT", "id": "P56522-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MAPRCWRWWSWSAWPGVRPLPSRSTPTPGFCKKFSTQETTPQICVVGSGPAGFYTAQHLL-KHHTRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSD--------RCAFRGNVVVGRDVSVPELREAYHAVVLSYGAEDHQPLEIPGEE-LPGVVSARAFVGWYNGLPENQK--LAPDLSC---DTAVILGQGNVALDVARILLT--PPEHLEKTDITEVALGVLRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLP--GTQPILDPSDFLGLQDRIKDVPRPRKRLTELLLRTATEKPGVEEAARRALA------SRAWGLRFFRSPQQVLPTPDGRRVAGIRLAVTRLEGVGESTRAVPTGDVEDLPCGLLLSSVGYKSRPIDPSVPFDP--KLGIIPNTEGRVVN-------APGLYCSGWVKRGPTGVITTTMTDSFLTSQVLLKDLKAGLLPSGP-RPGYTAIQALLSDRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDRREMLQLLGH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61578-1", "uniprot_id": "ADRO_MOUSE", "id": "Q61578-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MAPRCWHWWRWSAWSGLRPSPSRSTPTPGFCQKFSTQEKTPQICVVGSGPAGFYTAQHLL-KHHTHAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSD--------RCAFQGNVVVGRDVSVPELREAYHAVVLSYGAEDHQPLGIPGEE-LPGVVSARAFVGWYNGLPENQE--LAPDLSC---DTAVILGQGNVALDVARILLT--PPEHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLP--GTRPILDPSDFLGLQDRIKDVPRPRRRLTELLLRTATEKPGVEEAARQALA------SRAWGLRFFRSPQQVLPTPDGQRVAGIRLAVTSLEGVGESTRAVPTGDVEDLPCGLLLSSVGYKSRPIDPSVPFDP--KLGVIPNTEGRVVN-------VPGLYCSGWVKRGPTGVITTTMTDSFLTSQALLEDLKAGLLPSGP-RPGYVAIQALLSNRGVRPVSFSDWEKLDAEEVSRGQGTGKPREKLVDRREMLRLLGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22570-1", "uniprot_id": "ADRO_HUMAN", "id": "P22570-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MASRCWRWWGWSAWPRTRLPPAGSTPS--FCHHFSTQEKTPQICVVGSGPAGFYTAQHLL-KHP-QAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSG--------RCAFWGNVEVGRDVTVPELREAYHAVVLSYGAEDHRALEIPGEE-LPGVCSARAFVGWYNGLPENQE--LEPDLSC---DTAVILGQGNVALDVARILLT--PPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLP--GARPILDPVDFLGLQDKIKEVPRPRKRLTELLLRTATEKPGPAEAARQASA------SRAWGLRFFRSPQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYKSRPVDPSVPFDS--KLGVIPNVEGRVMD-------VPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDLKAGLLPSGP-RPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLLGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB58-1", "uniprot_id": "E7FB58_DANRE", "id": "E7FB58-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MKMMMNIMKGSLMKIHTLSRASRCLLADGGVRGLSS--VSARVCVVGGGPAGFYTAQQLL-KARQDAVVDIYERLPVPFGLVRFGVAPDHPEVKNVINTFTQTAQHE--------RCSFHGNVNVGKDVTIEELRQAYHAVVLSYGAEGNRSMGIPGED-LCNVFSAKDFVGWYNGVPSNTE--LCPDLSC---ETAVVLGQGNVALDVARILLS--PVDMLKETDITQNALEALTGSNVRRVLIVGRRGPLQIACTIKELREMVNLP--NTRADMLPADFEGIAEALKELPRPRKRLTDLMMKAVKE-------GGDEKL------EKSWGFRFFRSPVEVLAGVDGKKAAGVRLALNKLEGEGEGARSVPTGQLEDVDCGLIISSIGYKSLPIEPTVPFDP--RKAIVPNDMGRVQD-------AEGLYCSGWVKRGPTGVIATTMNDSFDTARVIIQDMETGKLDVSVNKPGAEAITGLLQTRGVRMVLFSEWEKINAEEERRGKALGKPREKLLDVEKMLKIAWS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3T9-1", "uniprot_id": "ADRO_DROME", "id": "Q9V3T9-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MGINCLNIFRR----GLHTSSAR-------LQVIQSTTPTKRICIVGAGPAGFYAAQLIL-KQLDNCVVDVVEKLPVPFGLVRFGVAPDHPEVKNVINTFTKTAEHP--------RLRYFGNISLGTDVSLRELRDRYHAVLLTYGADQDRQLELENEQ-LDNVISARKFVAWYNGLPGAEN--LAPDLSG---RDVTIVGQGNVAVDVARMLLS--PLDALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKELREMLKLP--NVDTRWRTEDFSGIDMQLDKLQRPRKRLTELMLKSLKE-------QGRISG------SKQFLPIFLRAPKAIAPG-------EMEFSVTELQQEA----AVPTSSTERLPSHLILRSIGYKSSCVDTGINFDT--RRGRVHNINGRILKDDATGEVDPGLYVAGWLGTGPTGVIVTTMNGAFAVAKTICDDINTNALDTSSVKPGYDAD-------GKRVVTWDGWQRINDFESAAGKAKGKPREKIVSIEEMLRVAGV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48360-1", "uniprot_id": "ADRO_YEAST", "id": "P48360-1", "name": "Probable NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "-------------------------MSFVQIRHISSQINRKTVSIVGSGPSGFYTAYHLLKKSPIPLNVTIWEKLPVPFGLSRYGVAPDHPEVKNCEETFTTCAEEFSSPTNQKHKFSFVGGITIGKEILLKELLDNQDAVILSYGCTGDRKLNIPGELGTKGVFSSREFVNWYNGHPDFAKDKRFTDFDWSKVSKVGIIGNGNVALDITRVLISNQIDEIWENTDISSLALNLLRRAPVKDVKLIARRDFVHSKFTNKELRELWELEKYGIRGRIDPKFFQKEMFDPSKYDRAFNRRVEMCSEYLKPFNERSKKNYKKAPPPSSGYDKFWELDYLKTPLKINRDDFG-AINSLSLCNNRLNEDNSLQPLKDVNNIMTYKVDLLITSLGYAGVPMPEFSKLSIGFDKDHIANKQGRVLTS--SGEIFPHLYASGWIRKGSQGVIASTMQDAFEVGDRVIQDLVV---------SGALSLENSIDLSNIKHTTWKDWERINKKELLRGKKEHKTRSKFLTFEELWNGVEGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: :.:**.**:***:* :* * * : *: ***** *:*********** :*** *. : : *.: :* :: : ** : .**:*:**. .: : : .* .* *:: ** **** * : .*:. . ::*:****:*::*:*:: : : ** :. ** * : *. * ::.**. :: * *****: :* . . * .. *. .* .:: . . .: : ::::* : : :. . *: ... *:: *:** . : :. : * **: ** :**: *. ***.:** .:* .. : .*: . .* : . : . :. *:::: * *: *.*.*:: .:: . ", "identical_positions": 108, "similar_positions": 134, "identity": "20.38%" }, { "cls_id": "homologset.agr.SGD:S000002786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62312-1", "uniprot_id": "LSM6_HUMAN", "id": "P62312-1", "name": "U6 snRNA-associated Sm-like protein LSm6", "aln": "MSLRKQTP----SDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIAL-EQTEEY--VNGQLKNKYG-DAFIRGNNVLYISTQKRRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62313-1", "uniprot_id": "LSM6_MOUSE", "id": "P62313-1", "name": "U6 snRNA-associated Sm-like protein LSm6", "aln": "MSLRKQTP----SDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIAL-EQTEEY--VNGQLKNKYG-DAFIRGNNVLYISTQKRRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZG07-1", "uniprot_id": "D3ZG07_RAT", "id": "D3ZG07-1", "name": "U6 snRNA-associated Sm-like protein LSm6", "aln": "MSLRKQTP----SDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIAL-EQTEEY--VNGQLKNKYG-DAFIRGNNVLYISTQKRRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W2P5-1", "uniprot_id": "Q9W2P5_DROME", "id": "Q9W2P5-1", "name": "U6 snRNA-associated Sm-like protein LSm6", "aln": "MS-RKEAL----SQFINQIHGRPVAVKLNNGVDYRGVLACLDGYMNICL-EQTEEY--VNGQLKNKYG-DAFIRGNNVLYISTQKRRV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06406-1", "uniprot_id": "LSM6_YEAST", "id": "Q06406-1", "name": "LSM complex subunit LSM6", "aln": "MSGKASTEGSVTTEFLSDIIGKTVNVKLASGLLYSGRLESIDGFMNVALSSATEHYESNNNKLLNKFNSDVFLRGTQVMYISEQKI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : .: ::*:.:* *:.* *** .*: * * * .:**:**:.* . **.* *.:* **:. *.*:**.:*:*** ** ", "identical_positions": 35, "similar_positions": 28, "identity": "39.77%" }, { "cls_id": "homologset.agr.SGD:S000002787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811M1-1", "uniprot_id": "RHG15_MOUSE", "id": "Q811M1-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQTSTN-------------------CDNSLEILNSAHQA-------TGAVQMRIKNAN-----------------------------------------SHQDRQ--------------------------------------------------------------------------SQTKS-------------MILTDAG----------------------------------------------------------------------KVTEPISRHR-RNHSQHVLK---------------------------DVIPPLEHP------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSGRKIEFYKDSKQQALP---------------------------------------------NMKTRHNVESVDLCGAHIEWAK-EKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGS-------------LELFNLQRSSSSELPSHCHIDRKEQKPE--HRKSFMFRLHHS--ASDTSDKNRVKSRLKKFISRRPSLKTLQ-----------EKGLIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKR--GLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKI---------------------ETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLR-AENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYC5-1", "uniprot_id": "RHG15_RAT", "id": "Q6AYC5-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQTSTN-------------------CDNSLETLNSAHQA-------TGAVQMRIKNAN-----------------------------------------SHPDRQ--------------------------------------------------------------------------SQTKS-------------MILTDAG----------------------------------------------------------------------KVTEPISRHR-RNHSQHVLK---------------------------DVIPPLEHP------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSGRKLEFYKDPKQQALP---------------------------------------------NVKPRPNAESVDLCGAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFGS-------------LELFSFQRSSSSEQPSHCHIDRKEQKPE--NRKSFMFRLHHS--VSDTSDKNRVKSRLKKFISRRPSLKTLQ-----------EKGIIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKR--GLEVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSDAKI---------------------ETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTLLR-AENESGNVAVHMVYQNQVAEFMLTEYDKIFSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53QZ3-1", "uniprot_id": "RHG15_HUMAN", "id": "Q53QZ3-1", "name": "Rho GTPase-activating protein 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKSTN-------------------SDTSVETLNSTRQG-------TGAVQMRIKNAN-----------------------------------------SHHDRL--------------------------------------------------------------------------SQSKS-------------MILTDVG----------------------------------------------------------------------KVTEPISRHR-RNHSQHILK---------------------------DVIPPLEQL------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSSRRIEFYKESKQQALS---------------------------------------------NMKTGHKPESVDLCGAHIEWAK-EKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRN-----------LELFKIQRSSSTELLSHYDSDIKEQKPE--HRKSLMFRLHHS--ASDTSDKNRVKSRLKKFITRRPSLKTLQ-----------EKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKR--GLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRI---------------------EAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR-AENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0D4-1", "uniprot_id": "RHG12_MOUSE", "id": "Q8C0D4-1", "name": "Rho GTPase-activating protein 12", "aln": "--MAERSG----KITAG-------QAYIEVEYDYEYDAKD-RKIVIRQGERYLLVKKTNDDWWQVRPDEN---SKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGSNYNSGQ-----------------TLNLSLDLTHNNGKFNSDSHSPKVSS------------QNRTRLFGHFPGPEFLDIEKTSFSQEQSCDS------------------------------------------------AGEGSERIQQDSESGDELSSS-------------------STEQMRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTW-----------------------KPPRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK----------------DSPTTTKLCLPENESP--PTS--SKHQDPG-----QEKYGLLNVTKITENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTIN-----------------------NQVAEADEAAEEETPDSPGVEKHDKEKD--QKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTRRPTLQAVR-----------EKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEH--GLDVDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLK-PERETGNIAVHTVYQNQIVELILLELSTVFGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDI5-1", "uniprot_id": "D3ZDI5_RAT", "id": "D3ZDI5-1", "name": "Rho GTPase-activating protein 12", "aln": "--MAERSG----KIASG-------QVYIEVEYDYEYEAKD-RKIVIRQGERYLLVKKTNDDWWQVRLDEN---SKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGSNYNSGQ-----------------TLNLSLDLTHNNGKFNSDSHSPKVSS------------QNRTRLFGHFPGPEFLDIEKTSFSQEQSCDS------------------------------------------------AGEGSERTHQDSESGDELSSS-------------------STEQMRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTW-----------------------KPPRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK----------------DSPTSTKLCLPENESP--PTS--TKHQDPG-----QEKYGLLNVTKITENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTIN-----------------------NQVAEADEAAEEEAPDSPGVEKQDKEKD--QKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTRRPTLQAVR-----------EKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEH--GLDVDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLK-PERETGNIAVHTVYQNQIVELILLELSTVFGR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWW6-1", "uniprot_id": "RHG12_HUMAN", "id": "Q8IWW6-1", "name": "Rho GTPase-activating protein 12", "aln": "MKMADRSG----KIIPG-------QVYIEVEYDYEYEAKD-RKIVIKQGERYILVKKTNDDWWQVKPDEN---SKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGPSYNQGQ-----------------TVNLSLDLTHNNGKFNNDSHSPKVSS------------QNRTRSFGHFPGPEFLDVEKTSFSQEQSCDS------------------------------------------------AGEGSERIHQDSESGDELSSS-------------------STEQIRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTW-----------------------KPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDTNDK----------------ESPTASKPCFPENESS--PSS--PKHQDTASSPKDQEKYGLLNVTKIAENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTIN-----------------------NQAVETDEGIEEEIPDSPGIEKHDKEKE--QKDPKKLRSFKV-SSIDSSEQKKTKKNLKKFLTRRPTLQAVR-----------EKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEH--GLDIDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------AAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLK-PEKETGNIAVHTVYQNQIVELILLELSSIFGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GV37-1", "uniprot_id": "A0AC58GV37_DANRE", "id": "A0AC58GV37-1", "name": "", "aln": "--MSERDGRCDLSIAPG-------QVYIEVEYDYEYKAKD-KLISIRQGECYMLVRKTNEDWWQVRREEG---TKAFYVPAQYVREVRR-ALMPPPKPRAKPPN----VLEITHCRSSNENLNQRAPTEKSTFGRPPPSTTPSPLPG------------------QQTPPLLLRDSNHNPGMK----------------SVVAELTLLNNNNHHNFHHANPTLP-------------QGRAESPPRDQGCQGKLTGGLSVDTDGSVS-------------------------------------------------PGDGVEKMRNDSESGDELSSS-------------------STEHIQSVSLSGQGRPESPVYTNLQELKICQSSV------------------------PPVPSTSPLHVLGDWETHKDTSGRNFYFNRTTQERTW-----------------------KPPR-SRDNGVSRGDTSNTGDMEPLSSEENCPSTHSSQSDSQYG---SPPRGWSEELDEHGHTLYVSEYTNEKWIKHVDEQGRPYYYSADGSRSEWELPKYNLSPP------------ISGEAPKSHSLERKQQEPIVLTK-WRHSTYVLDISDKTTWFYLFA-------NKKLPFKNRWFSVNHPP--RGFGLPVYREPS------EKCGVLNVTKITEHGKKVR-KNWASTWTVLQGSSLLFAKGQGSG--TSWSYCHNGSFPELLLSLLSNWKRSIKPRPAVSYTHCRRARASSFGGNQ-SKPEFTVDLRGGSVEWASKEKSSKKHVIELKTRVGTELLIQSEIDSVINDWFRALSETIN-----------------------THAWESDEAIEEDMPESPGSEKHDKEKD--PRDSKKNRVVKN-SSMESSEQKKTRVKLKKFLTRRPTLQAVR-----------DKGYIKDQVFGCSLTALCQREGTSVPNFVKMCIEHVENT--GLNVDGLYRVSGNLAVIQKLRFAVN------------------HDEKVNLDDSKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKNSDYKQRV---------------------QSIKDLIKQLPKPNQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLR-PEIETGNMAVHMVYQNQIVELILLEYENIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QA49-1", "uniprot_id": "A0A8M9QA49_DANRE", "id": "A0A8M9QA49-1", "name": "", "aln": "--MADR------SIAPG-------QTYIEVEYDYDYKSKD-RLITIKHGESYLLVKKTNDDWWQVRKDDA---SKPFYVPAQYVREVRR-ALMPPPKPLNIAGRGGPAPNRPSALEIQRPNDNKKS---------PCPSPSSTALLP------------------PRD----DRGSPVSPTR-----------------HLPPAQMNTFPGSLPCFRAESPGSKL------------DGERD---KDKDSERKDRGEKAAVQEELAEE------------------------------------------------GGDS-DKNRIDSESGDELSSG-------------------STDNLQSLG-SGQGRPDSPVYTNLQEMKISQSST------------------------PPLPSSSPIHTNGDWETHKDQNGRHYYYNRSTQERTW-----------------------KPPR-ARDSLPRKEEKHDMTDTEVLSSEENCLS---SQSDSQYG---SPPRGWSEEMDEHGHTLYVCDYTNEKWLRHTDERGRLYYYSADGSRSEWELPKIGLKSQSNHT------PLMPGDLHKTRSLDRRLPDPIPISRTQRHSIYSHETNDKLKQKFVKVRQSFLPRRKTTLRSHPYFPQDTKTGSPDSDSSCPSSPKPPHSPSEKCATLNMTKITEHGKKVR-KNWTSYWTVLQGSLLIFNKGQGGG--SGW-----------------------------------------FGRDQKSSVEYSVDLKGGSVDWASKDKSSKKHVLELKTRQGTELLLQSDSDGLVNDWHKALTEAIH-----------------------TYMWESDEAIEEDMPESPENEKHDKEKD--RKNSKKARDIKKTASMDNAEQKK-KNKLVVLLLGRPTLQAVK-----------DKGYIKDQVFGCSLSSLCQRENSTVPRFVWLCIEQVEKN--GLGVDGLYRVSGNLAIIQKLRFAVN------------------HEEKIDLGDSKWEDIHVTTGALKMFFRELPEPLFTYTFFSDFISAIKMPDYKQKV---------------------QTVKDLMKKLPRPNHDTIQVLFKHLKKVIQHVDENRMTTQSVAIVFGPTLLR-PEIETANMAVHMVYQNQIVELILMEYDTIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B2D3-1", "uniprot_id": "A0A8M2B2D3_DANRE", "id": "A0A8M2B2D3-1", "name": "", "aln": "--MNPDPLFAPQHVWATMSL----SQQVLVNYEYTYTARDGRNVSIKPNEHYILVNKTNEEWWHVQKDAA---DKPFYIPAKYVTELPPETSQTPLDPPEEFSG--YESLQFGSQTADPAEVTLRVPDSIKRDTEKDGHRISTFIIPKEFFELKGLDPDPIKTEAEAGPPVSSNTSSPTNG-------------ETAFIILPPPVYTVNTTQSTETDTRSVDDP--------KDSVGRPRVDSSTIDEDIQMLNRAGWSEVLDVMGKEKNVYESLDTVREPES---PKDEADMTVNTTPVTPDAPMVEDD----TAVYVNIPRKRQTTINNSSPIASLLQD-----FPEPPENFLLDSAGWQVHTDDQSGQEFYYQPSTGRSTWENPLSSRSMESPVGTEGGRSPPSFPQSPACSPVAPAPRRWSSDWEKVLDESTGRHYFFNTVSGQSSWDPPE------DVDSPGRLMFLDDCPPPLPEEDYPASPELEEASPVSIPAEYSLIHVKKVSIPRVSLD--RSSPAGWSLDIDSEGTWTFTSEYTQEQWIKSLDDQGRTYYYLRDGSKSQWNLPEINPGQGGVAAQWLALLPYSKNVAGSSPGWYSASPGQYGVGNGASGEQDTVGSNWR----------------HSAGYPDDKNHSSYIQNTSDSEASSSPDTPHNVSNLEKAGILNKTKVSENGKKVR-KNWGHSWTVLHGGKLTFHKDPKSTPAG------------------------------------------ASSKTNQILPEFTVDLKGATINRAPKDKSSKKNVLELKTRTGAEYLIQYDTDSIIQDWHKVILDTIHQLN---------------------GDQHHSEEEDEVIDKSPTLDREERPFE--KRTMSTATRQPSTSSTSEAEQKKVRTKLKKFLLKRPTLQSVK-----------DKGYIRENVFGCHLHNLCSQEKTRVPSFVEKCIRAVEKR--GLEIDGLYRVSGNLAVIQKLRFKAD------------------HED-LDLEEGNWD-IHVITGALKLFFRELQEPLFPYNLFNEFICAIKTPDYYSKI---------------------SHMRNLVRSLPPPNHDTMEALFSHLRRVIQHGNENRMTVQNVAIVFGPTLLK-PEEETASIATYMVFQNQIVEFLLSEFESIFHM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B765-1", "uniprot_id": "A0ACD6B765_DANRE", "id": "A0ACD6B765-1", "name": "", "aln": "--MGETGKMTSVHTLG----------LVLVEFEYEYEGRDGHMVCIKPNERYILLAKTNDHWWHVCKDER---AKPFYIPAKYVKELPPN-IPSPLDYREPPGPDVKPAVPDLTETRKADEVTIRLRS--KGNYHKTENRMSTFGVPLDLHEPPSYKHGGPSDSLISLSSVSASDSSKQKKRMSHAPNLLFGSHSNLPTELVPDKFRVPSFSPADPLHRPIPAKPVEIPIIKNLNETKPHRTSPELESPIEPESESSSSEPMPSPDSE-NIYESISDLNIDLSSLTDKEPAGLPDTQTTTSSLPPSIKTDNDPTTALYANVADIKKNIPRSSNSSVSTCSSPGITLSPAPDSISPPSSAEWRVHTDHDSGKEFYYHPATGQSSWSDPRSP---QPGAGMESVTAP-----VPASSP--PSAR---SDWEQLLDEATGRHYYYNHASNKTSWTAPEPSAPASSKQGPHSQDKDKERPPPLPEEDYPKNQHEESHISFQLPKDFQLPQIKRAVIPRAVMDTNKDVPTGWTQSVGTDGKSVFTSELTHEQWIQSKDEKGKLYYYSKDGSKCQWTLPEALVPPGQPMNGNGVEQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIASDNASDAS----------------SSGNSPESQHYDKKFRRRRN-LSSYSTDSHSHHSSLEKAGILNKTKVAENGKRLR-KNWAQSWTVLHDGVLTFHKDPKFAPAG------------------------------------------MSSKTNQIVPEYTVELKGATLSWASKEKSSKKNVLELKTRHGSEYLIQYDTDSIIQDWQKIILDTIKLLH---------------------EHGHNSEDEAEDVP-----EKSPLPAD--KEKKPEAARLSSTSS-IDTDQGRVRTKLRKFLQRRPTLQSVK-----------EKGYIKENVFGCHLDTLCHRENTTVPKFVEKCIRSVEKR--GLKIDGIYRVSGNLAVIQKLRYKAD------------------HEEDLDLEDGQWEEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQISDYSQKV---------------------SYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLR-PQEE-SNITMHMVFQNQIVELVLNEFNELFQTK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVEG--------DVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGDPAPAPQPSVPQQR---PAVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTGGQRNSLAPG--------------GPACLYVRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLAPSDSE-NVYEAIPDLRCPPRAESPKQVDDPPE--------------------PVYANVERQPRATSPRSAAAP------------------PRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFET--------PEGTTSP------ATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEEL---EEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASP--LVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPR------------------------------------SVRKSSQDSDTP----------------AQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELS---------------------ADLLQGEEGEPSSADFGSSERLGSWRE--EDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLR-----------DKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEAR--GLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLR-PEMEEASMPMTMVFQNQVVELILHQCADIFPPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVEG--------DVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGDPVPAPQPSVLQQR---PTVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTSGQRNSLAPG--------------GPACLYLRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLARSDSE-NVYEAIPDLRCPPRAKSPKQVDEPPE--------------------PVYANVERQPQVTSPRSAAAP------------------PRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------PEGATSP------TTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEEL---EDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSP--LVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPR------------------------------------SGRKSSQDSDTP----------------AQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASG-----------------------------------------LRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELS---------------------ADLPQREEGEPSSADFGSSERLGSWKE--EDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLR-----------EKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEAR--GLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLR-PEMEEASMPMTMVFQNQVVELILHQCADIFPPH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVVG--------DVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGNPAAAAPP-GPHPS---PAAPEPLAYDYRFVSAAATAGPDGAPEESGGRASSLCGP-------------------AQRGAATQRSSLAPG--------------LPACLYLRPAAPVRPAQSLNDLACAAVSPP------------AGLLGSSGSFKACSVAGSWVCPRPLARSDSE-NVYEVIQDLHVPPPEESAEQVDDPPE--------------------PVYANIERQPRATSP-GAAAA------------------PLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------AEGAASP------ATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN------EPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSP--LTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPR------------------------------------SIHKSSQDGDTP----------------AQASPPEEK-VPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELS---------------------AELPP-EESESSRVDFGSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQRRPTLQSLR-----------EKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEAR--GLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRS---------------------RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVFQNQVVELILQQCADIFPPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BRR9-1", "uniprot_id": "RHG09_HUMAN", "id": "Q9BRR9-1", "name": "Rho GTPase-activating protein 9", "aln": "-MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSR--------------------------------------------------------------------------------------------------------------------AQASSEQPPPLPRKMCRSVSTDN----------------------------------------------------LSPSLLKPFQEGPSGRSLSQE-----------------DLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSP-----------------------PPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWK------------------------------------------------------PPRRSRSETNPG-----------SMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGS--------------------------------------------------LSLSQRTSQLDPP-----------------ALQAPRPLPQLLDDP-----------------HEVEKSGLLNMTKIAQGGRKLR-KNWGPSWVVLTGNSLVFYREPPPTAPSSG------------------------------------------WGPAGSRPESSVDLRGAALAHGR-HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQ-----------ERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKR--GLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCL---------------------SQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFR-PEQETSDPAAHALYPGQLVQLMLTNFTSLFP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91V57-1", "uniprot_id": "CHIN_MOUSE", "id": "Q91V57-1", "name": "N-chimaerin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTLFDTDEYRPP-------------------VWKSYLYQLQQEAPHPRRVTCTCEVENRPKYYGR----------------------------------------EYHGMISR------------------------------------------------------------------------EETDQLLS------------VAEGSYLIRESQRQP------------------------------------------------------------------------GTYTLALRFG--------------------------------------------------------SQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAA---------------------------------------------------EYIAKMTINPIYEHIGYTTLNREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRAT------------------------------LKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKP-----------DLKHVK-KVYSCDLTTLVKAHITKRPMVVDMCIREIESR--GLNSEGLYRVSGFSDLIEDVKMAFDR-----------------DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQL---------------------ETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06407-1", "uniprot_id": "RGA2_YEAST", "id": "Q06407-1", "name": "Rho-type GTPase-activating protein 2", "aln": "--MSADPINDQSSLCVR------CNKSIASSQVYELESKKWHDQCFT---CYKCDKKLNADSDFLVLDIGTLICYDCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRGLCCMDCHEKLLRKKQLLLENQTKNSSKEDFPIKLPERSVKRPLSPTRINGKSDVSTNNTAISKNLVSSNEDQQLTPQVLVSQERDESSLNDNNDNDNS------------KDREETSSHARTVSIDDILNSTLEHDSNSIEEQSLVDNEDYINKMGEDVTYRLLKPQR--------------------ANRDSIVVKDPRIPNSNSNANRFFSIYD-------------KEETDKDDTDNKENEIIVNTPRNSTDKITSPLNS----------------------PMAVQMNEEVEPPHGLALTLSEATKENNKSSQGIQTSTSKSMN-------------------HVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTADNLLPHKKVAPSPNKKLSRSFSLKSKNFVHNLKSKTSEMLDPKHPHHSTSIQESDTHSGWGVSSTHTNIRK----------------------SKAKKNPVSRGQSDSTIYNTLPQHGN----------FTVPEFNHKKAQSSLGSISKKQNSNDTATNRRINGSFTSSSSGHHIAMFRTPPLESGPLFKRPSLSSESAHHRSSSLQTSRSTNALLEDDS--------------------------------TKVDATDESATSLEKDFYFTELTLRKLKLDVRELEGTKKKLLQDVENLRLAKERLLNDVDNLTREKDKQSASSRESLEQKENIATSITVKSP------SSNSDRKGSISNASPKPRFWKIFSSAKDHQVGDLESQQRSPNSSSGGTTNIAQKEISSPKLIRVHDELPSPGKVPLSPSPKRLDYTPDGSHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIGLNMEGLYRKSGSQTLVEEIENEFAQNNS-----------LHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIH--DFDGEKDIVDMKERNYIVEFILGNYRDIFKQA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : : : . . : . . : :::.. * . * .: ** :: ** :*:** ** ::.:. . .: : :: :..** :*.* *:.. : : : . . :* : :.:. * *: :: * *. .. .:**.*:*:: : : :.:::: : :* ", "identical_positions": 26, "similar_positions": 77, "identity": "2.18%" }, { "cls_id": "homologset.agr.SGD:S000002789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A087WNP0-1", "uniprot_id": "A0A087WNP0_MOUSE", "id": "A0A087WNP0-1", "name": "", "aln": "MADKMGLSLEDIIKLNKIQQGCHN--------------------RPDSRVNRGTGPKRYKPGITN------SGRNRLPPYRRPKQLQDKGQHDHFVGSFRAGNHMDTG-GKLLLSNLHFGVSDADIQKLFA-EFGTLRKSAVHYDRSGQSLGTAHVHFERKADALKAMREYNGVPLDG--RPMNIQLVTSTIDTRPRPAQS-RNRGGMPRNPGSGGYGGGG-TRRETLEDSQGRG-GTSRNSKKKQQQQQQQQQ---------------------------------------------------LSAEELDAQLDTYWEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W7J0-1", "uniprot_id": "A0A3B2W7J0_MOUSE", "id": "A0A3B2W7J0-1", "name": "", "aln": "MADKMGLSLEDIIKLNKIQQGRHN--------------------RPDSRVNRGTVPKRYKPAITR------SGRNRLPPYRRPKHLPDKGQHDHFVGSFRAENHMDTG-GKLLLSNLHFGVSDADIQKLFA-EFGTLRKSAVHYDRSGQSLGTAHVHFERKADALKAMREYNGVPLDG--HPMNIQLVTSTIDTRPRPAQS-RNRGGMPRNPGSGGYGGGG-TRRETLGDSQGRG-GTSSNSKKQQQQQQQQTQ---------------------------------------------------LSAEELDAQLDTYWEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZY4-1", "uniprot_id": "E9PZY4_MOUSE", "id": "E9PZY4-1", "name": "", "aln": "MADKMDMSLEDIIKLNKMQQGRRD--------------------RPDSRVKRGTGPKRYRPAFTH------GGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTG-GKLFLSNLHFGVSDADIQLLFA-EFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDG--RPMNIHLVTSQIDRQGRPALN-SDKGGMTRNPGSGVLSGGG-TKRWTLGGSQGSGRGTSRNSKLQQQQQQQQQQ-------EEQKHQKQQQQKQQQQQQKQGQNHQHQQQQKEQQQQQQQKELQQLSVEELDAQLDYYQDMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K9J7E2-1", "uniprot_id": "K9J7E2_MOUSE", "id": "K9J7E2-1", "name": "", "aln": "MADKMDMSLEDILKLNKMQQGRLD--------------------RPDSRVKRGTGPKRYRPAFTH------DGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTG-GKLFLSNLHFGVSDADIQLLFA-EFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDG--RPMNIHLVTSQIDRQGRPALN-SDKGGMTRNPGSGVLSGGG-NKRWTLGGSQGRGRGTSRNSKLQQQQQQQQQQQQQQQQQEEQKHQKQQQQKQQQQQQKQGQNHQHQQQQKE-------KELQQLSVEELDAQLDAYQEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RBB1-1", "uniprot_id": "M0RBB1_RAT", "id": "M0RBB1-1", "name": "", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAV--QAAARVNRGGGPMRNRPAIARG-AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDG--RPMNIQLVTSQIDTQRRPAQS-INRGGMTRNRGSGSFGGGG-TRRGTRGGSRGRGRGTGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08583-1", "uniprot_id": "THOC4_MOUSE", "id": "O08583-1", "name": "THO complex subunit 4", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAV--QAAARVNRGGGPMRNRPAIARG-AAGGG-RNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDG--RPMNIQLVTSQIDTQRRPAQS-INRGGMTRNRGSGGFGGGG-TRRGTRGGSRGRGRGTGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86V81-1", "uniprot_id": "THOC4_HUMAN", "id": "Q86V81-1", "name": "THO complex subunit 4", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGGA--QAAARVNRGGGPIRNRPAIARG-AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDG--RPMNIQLVTSQIDAQRRPAQS-VNRGGMTRNRGAGGFGGGGGTRRGTRGGARGRGRGAGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJW6-1", "uniprot_id": "ALRF2_MOUSE", "id": "Q9JJW6-1", "name": "Aly/REF export factor 2", "aln": "MADKMDMSLDDIIKLNRNQR----------------------------RVNRGGGPRRNRPAIAR------GGRNRPAPYSRPKPLPDKWQHDLFDSGCGGGEGVETG-AKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYKGVPLDG--RPMDIQLVASQIDPQRRPAQS-GNRGGMTRSRGSGGFGGRG---------SQGRGRGTGRNSKQQQ-----------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V3E7-1", "uniprot_id": "Q9V3E7_DROME", "id": "Q9V3E7-1", "name": "", "aln": "MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTGGQQRFAGGARRGGANAGGSPRKPGSVLKGPRGGVAAGAVQKAKFPR-GDVNSAWKHDMYDGPKRGAVGGGSGPTRLIVGNLDYGVSNTDIKELFN-DFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDG--RPMTIQLAVSDVAVLTRPVAA-TDVKRRVGGTAPTSFKRGG----GQAGGTARRGFKRPVGGKPAAGGQRRERK-------------------------------------------------APPTAEELDAELDSYINDMKI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK76-1", "uniprot_id": "Q9VK76_DROME", "id": "Q9VK76-1", "name": "", "aln": "MSDKMKMSLDDIIKMKFNKNKFVN--------------------AKNERVQGGSIRKRNSEGGLRG--------IQRSRNGTGFIRKSKFKQETLLKPPKKP-------TLVMVCNLDYGVDDDDIMELFN-QDGVVEKGFVHYDRDGNSLGTAHLSFKYREEAFQIIEQFHGVRLDG--RRLKLHLVQNTRNFKRTDVDD-LSLR--MGSFKTRFLQNGTFKTRSLQNGFQKSRLFRNSSFKPR-------------------------------------------------------------PFKKHNFKSRAFDTDF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12159-1", "uniprot_id": "YRA1_YEAST", "id": "Q12159-1", "name": "RNA annealing protein YRA1", "aln": "MSANLDKSLDEIIGSNKAGSNRAR-----------------------VGGTRGNGPRRVGKQVGSQ---------RRSLPNRRGPIRKNTRAPPNAVARVAKLLDTTREVKVNVEGLPRDIKQDAVREFFASQVGGVQRVLLSYNERGQSTGMANITFKNGELARRAVERFNGSPIDGGRSRLRLNLIVDPNQRPVKSLADRIKAMPQKGGNAPRPVKRGP-----NRKAAMAKSQNKPKREKPAK-----------------------------------------------------------KSLEDLDKEMADYFEKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: **::*: . * : : . . : : : .* .:.: : :* : * :.: : *:. *.* * *.: *: * : :..::* :** : ::* . . . . * . :. : : : ", "identical_positions": 20, "similar_positions": 51, "identity": "6.15%" }, { "cls_id": "homologset.agr.SGD:S000002790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4D5-1", "uniprot_id": "D4A4D5_RAT", "id": "D4A4D5-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02401-1", "uniprot_id": "RLA2_RAT", "id": "P02401-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZN03-1", "uniprot_id": "D3ZN03_RAT", "id": "D3ZN03-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEAEDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDNMGFDLFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5F8MPY2-1", "uniprot_id": "A0A5F8MPY2_MOUSE", "id": "A0A5F8MPY2-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILGSVGIEADDDRLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P99027-1", "uniprot_id": "RLA2_MOUSE", "id": "P99027-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05387-1", "uniprot_id": "RLA2_HUMAN", "id": "P05387-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGK-NIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05389-1", "uniprot_id": "RLA2_DROME", "id": "P05389-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVAAYLLAVLGGKDSPANSDLEKILSSVGVEVDAERLTKVIKELAGK-SIDDLIKEGREKLSSMPVGGGGAVAAAD--AAPAAAAGGDKKEAKKEEKKEESESEDDDMGFALFE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02400-1", "uniprot_id": "RLA4_YEAST", "id": "P02400-1", "name": "Large ribosomal subunit protein P2B", "aln": "MKYLAAYLLLVQGGNAAPSAADIKAVVESVGAEVDEARINELLSSLEGKGSLEEIIAEGQKKFATVPTGG--ASSAAAG-AAGAAAGGDAAEEEKEEEAKEES---DDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*:*** . **: *: *:: :: *** *.: *:.:::..* ** .::::* :* *::::*.** * :** ** **... * *::* **** *::*** **:", "identical_positions": 44, "similar_positions": 39, "identity": "37.93%" }, { "cls_id": "homologset.agr.SGD:S000002793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05197-1", "uniprot_id": "EF2_RAT", "id": "P05197-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58252-1", "uniprot_id": "EF2_MOUSE", "id": "P58252-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLSAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13639-1", "uniprot_id": "EF2_HUMAN", "id": "P13639-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVM4-1", "uniprot_id": "A0A8N7UVM4_DANRE", "id": "A0A8N7UVM4-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIREIMDKKSNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLYYELSENDSAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPDELFQTFQRIVENVNVIISTYGEGEHGPMGNIMVDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGDKKKGDLPPTERAKKVEEMMKKLWGDKYFDPSCGKFSKTANNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKEETQKLIEKLEVKLDAEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQRYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMVPTTDKGRFYAFGRVFSGIVSTGQKVRIMGPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFENSHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIVAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSDESDQVCLSKSPNKHNRLYMKSRPFPDGLAEDIDKGDVSSRQELKLRARYLAEKYEWEVAEARKIWCFGPDGTGPNILVDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHADAIHRGGGQIIPTARRVLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPIFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPYDVNSKPSQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P3J5-1", "uniprot_id": "EF2_DANRE", "id": "Q6P3J5-1", "name": "Elongation factor 2b", "aln": "MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYYELTENDLAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGE---AQLSPADRCKKVEDMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEWEVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13060-1", "uniprot_id": "EF2_DROME", "id": "P13060-1", "name": "Eukaryotic translation elongation factor 2", "aln": "MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYND-DGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFK----------------IDVVKLMNRLWGENFFNAKTKKWQKQKE-ADNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLSQYLDKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32324-1", "uniprot_id": "EF2_YEAST", "id": "P32324-1", "name": "Elongation factor 2", "aln": "MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQK----TDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYAD---EVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFG----------------VDKAKMMDRLWGDSFFNPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****::* :*** *:********************* :****:.*:***:************ *********:: *: ::* *.: .: .********************************* :.*************:.*****::.:**:********:. ::*:*** * **.****::** : :*:: : * *:*.***********::**: * ** . .:*.:***: :*:. *: : .:.* *:* :****:::* ****::*:* *:**: : *. ::*: :**.***.*** :***.:***:**.:******.** ** * ***** ** .:.:*.***.. **:*:******:************:* * :* * ** ***:.****:**: *.***.:*****:**.*:* *.*** ****:****:****:** . :***:**********:**** **. ************:**** * :.******:**:*********:***.*** :*:* * ***:*****. **. .**********: :*: *: : :. *::* :..::::* *** :::.* ::*::***********.***:: * **.****:********.****:*** : *::*.**.:: *****:************* ** ** : *.*:: **::* ****** .*****.***::**:*..*.* ***:*.**************.:**. ******** *****. * .** : *:. :* :***:*:** :* .:: ***", "identical_positions": 514, "similar_positions": 200, "identity": "59.42%" }, { "cls_id": "homologset.agr.SGD:S000002794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM32-1", "uniprot_id": "MUS81_RAT", "id": "Q4KM32-1", "name": "Structure-specific endonuclease subunit MUS81", "aln": "-MAEPVRLGRKRPLPVCPNPLFVRWLTEWRDEAASRGRHTRFVFQKALRSLQRYPLPLRNGKEAKILQHFGDRLCRMLDERLK-----EHLASGGD----HAPSSPSGKKR--ASKGPPAQVQGSSMPVPT-QPQAGSTNAGYWPAQNSGAREILLQLYREHLNSDGHSFLTKEELLQKCAQKTPR--VVPESS---RPWPALRGLLHRNLVLRTHRPARYALTPEGLELAQKLAEAE--------------------------GLSTLNTAFQPEEHHEES--------------PVPEAILSEP------GTTEVGVQQRPLELR------------------------------PSEYRVLLCVDIGETRGAG--HRPEMLRELQRLRVPHTVRKLHVGDFVWVAQETRPRDP--ERP---GELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLGHRIYLVEEHG-SVQNLSLPESTLLQAVTNTQVIDGFFVKRTMDIKESAGYLALLTKGLERLYQG--------HTLHSRPWGTPGDAESE-AKPSTNPLCSLLTFSDFNAEAVKNKAQSVREVFARQLMQVRGLSGEKAAALVDRYSTPASLLAAYDACATTKEQEMLLSTVK-CGRLQRNLGPALSRTLYQLYCSHSPLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZJ0-1", "uniprot_id": "MUS81_MOUSE", "id": "Q91ZJ0-1", "name": "Structure-specific endonuclease subunit MUS81", "aln": "-MAEPVRLGRKRPLPVCPNPLFVRWLTEWRDEAASRGRHTRFVFQKALRSLQRYPLPLRSGKEAKILQHFGDRLCRMLDEKLK-----QHLASGGD----HAPSSPSGKKG--ASKGPPEQVQDSSMPVPT-QPQAGSTSVGYWPAQNSGAREILLQLYREHLNSDGHSFLTKEELLQKCAQKTPR--VVPGSS---KPWPALRSLLHRNLILGTHRPARYALTPEGLELAQKLAEAE--------------------------GLSTRHAGFRPEEHHGED--------------SAVPEALSEP------GTTEGAVQQRPLELR------------------------------PSEYRVLLCVDIGETRGAG--HRPEMLRELQRLRVPHTVRKLHVGDFVWVAQETRPRDP--ERP---GELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLGHRVYLVEEHG-SVHNLSLPESTLLQAVTNTQVIDGFFVKRTMDIKESAGYLALLTKGLERLYQG--------HTLRSRPWGAPGAAESE-AKPSTNPLCSLLTFSDFNAEAVKNKAQSVREVFARQLMQVRGLSGEKAAAVVDRYSTPASLLAAYDACATAKEQEMLLSTIK-CGRLQRNLGPALSRTLYQLYCSHSPLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NY9-1", "uniprot_id": "MUS81_HUMAN", "id": "Q96NY9-1", "name": "Structure-specific endonuclease subunit MUS81", "aln": "-MAAPVRLGRKRPLPACPNPLFVRWLTEWRDEATRSRRRTRFVFQKALRSLRRYPLPLRSGKEAKILQHFGDGLCRMLDERLQ-----RHRTSGGD----HAPDSPSGENSP-APQGRLAEVQDSSMPVPA-QPKAGGSGS-YWPARHSGARVILLVLYREHLNPNGHHFLTKEELLQRCAQKSPR--VAPGSA---RPWPALRSLLHRNLVLRTHQPARYSLTPEGLELAQKLAESE--------------------------GLSLLNVGIGPKEPPGEE--------------TAVPGAASAE------LASEAGVQQQPLELR------------------------------PGEYRVLLCVDIGETRGGG--HRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDP--ANP---GELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLERRVYLVEEHG-SVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRGLQRLYQG--------HTLRSRPWGTPGNPESG-AMTSPNPLCSLLTFSDFNAGAIKNKAQSVREVFARQLMQVRGVSGEKAAALVDRYSTPASLLAAYDACATPKEQETLLSTIK-CGRLQRNLGPALSRTLSQLYCSYGPLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXA9-1", "uniprot_id": "MUS81_DANRE", "id": "Q7SXA9-1", "name": "Structure-specific endonuclease subunit MUS81", "aln": "MPTDQVCLGRKRPLPSCPNPLFLQWLTELRDSAKEKGLKTHFVYQKAINSLKKYPLPLKNGKEAKILQNFGDGICKILDERLQ-----KHYRENGSDAAVHLASSKQMEESQKEPSGNFSEHTKLTQKEVR-KEKGAKKKREYVPQKRSGGYAVLLTLYRHMQMPGSKGFMFRNELQTEAQPLCEKSFTVPDLGSKYTAWSSVSTLIQKELVVKTHNPARYSLTDQGLSLAEKLDSEETGTRHEDVDSQD--------------GQNVVDLTLEEEDEDEEKESWSSERPAVALPVNQARGLMSESDPMGKSQTSETGRTAMGWHLS------------------------------PGSYDIVLCVDLCETTGGSSVRKQELVKELQRNSVTFDVRKLNVGDFLWVARERVTPVPGQLRPPVGKELVLDYIIERKRMDDLCGSIIDGRFREQKFRLKRCGLRKPIYLVEECGSAAAHLSIPESTLQQAIVNTQVVDGFFVKRVQDAKESAAYLTIMTRYLQKLYQN--------CTLLCRSRELEGDGEAESEKMVANLSCSLMAFTEFNYGAIKNKCQTVREVFARQLMQISGVSGDKAAAVLKHYSTVSSLLQAYDKCSSETEKEKLLSSVK-YGKLKRNLGPALSRTIYQLYCTRGPLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3T1-1", "uniprot_id": "Q9V3T1_DROME", "id": "Q9V3T1-1", "name": "Crossover junction endonuclease MUS81", "aln": "------METRLEVLLREPNPLFTRWLERWLREAERREQKSQFSLRQALESLKSYPLPLASGRDCSILRGFGGTLCQLIDEELR-----HHRG-----------------------------LQLLPQEAVV-QER-----------------------YEQQVQAVVRKVQEKQLEHQKRQNKCDR---------------------------------PRKLTKKDLAELAALEERE-----------------------------------------------------------------------------------RVVRMK------------------------------PGQFQLLLLVDTQETSGKNKRVLDQTRSYLESLGARHEVRRLTIGDFLWVAQDQE-----------GNELVLPYIVERKRMDDLASSIRDGRFHEQKHRLQHCGLQHIIYLVEDYG-DNEQLGLPLDSLQQALTNAKVQTGVRVVRTANHYRSMSYLAGMSRTLGQIFAG--------KKLHSVDRGAIDQSTCL----LTHSDLGLLKFRALYEDSAKNAQLTVREVFVQQLLQLHSLSLERAMAIVERYPTPRWLLDAYAECADQKQARLLLASIP-CGPLERPLGDKISQCLHEFYSTHFR--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04149-1", "uniprot_id": "MUS81_YEAST", "id": "Q04149-1", "name": "Crossover junction endonuclease MUS81", "aln": "-----------MELSSNLKDLYIEWLQELVDGLTPKQEQLKIAYEKAKRNLQNAEGSFYYPTDLKKVKGIGNTIIKRLDTKLRNYCKIHHISPVEAPSLTQTSSTRPPKRTTTALRSIVNSCENDKNEAPEEKGTKKRKTRKYIPKKRSGGYAILLSLLELNAIPRGVSKEQIIEVAGKYSDHCMTPNFSTKEFYG--AWSSIAALKKHSLVLEEGRPKRYSLTEEGVELTKSLKTADGISFPKENEEPNEYSVTRNESSEFTANLTDLRGEYGKEEEPCDINNTSFMLDITFQDLSTPQRLQNNVFKNDRLNSQTNISSHKLEEVSDDQTVPDSALKAKSTIKRRRYNGVSYELWCSGDFEVFPIIDHREIKSQS--DREFFSRAFERKGMKSEIRQLALGDIIWVAKNKNTG----------LQCVLNTIVERKRLDDLALSIRDNRFMEQKNRLEKSGCEHKYYLIEETM--SGNIGNMNEALKTALWVILVYYKFSMIRTCNSDETVEKIHALHTVISHHYSQKDLIVIFPSDLKSKDDYKKVLLQFRREFERKGGIECCHNLECFQELMGKGDLKTVGELTIHVLMLVKGISLEKAVAIQEIFPTLNKILMAYKTCSSEEEAKLLMFNVLGDAPGAKKITKSLSEKIYDAFGKL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *: .** . : :: .:* ..*: .: : . :: :*. : : :* .*: .* : . . . ** :.: * : .: ...: :. :* * . . :: :*:* :**::***:: : ** *:****:***. ** *.** *** **::.* : **:*: ::. .:* *: * . : *. : .: : : : : : * . : : *. :* *: : *: : .:* ::* *: . :.* :* ** *: : . *: .: . : : :*. : : : . ", "identical_positions": 65, "similar_positions": 115, "identity": "9.8%" }, { "cls_id": "homologset.agr.SGD:S000002795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921A2-1", "uniprot_id": "MYCT_RAT", "id": "Q921A2-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAP--GGERSLLAA-ESAASLQGA--------ELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQ----MRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEE--KEASAAGPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCTCGT----------------ADSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHK1-1", "uniprot_id": "MYCT_MOUSE", "id": "Q3UHK1-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAP--GGERSLLAA-ESAASLQGA--------ELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQ----MRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEE--KEATAAGPIICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCSCGA----------------ADSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QE2-1", "uniprot_id": "MYCT_HUMAN", "id": "Q96QE2-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQ----LSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEE--KEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGT----------------SDSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA61-1", "uniprot_id": "A0A8M2BA61_DANRE", "id": "A0A8M2BA61-1", "name": "Proton myo-inositol cotransporter", "aln": "-------------------MEDQR----------------AYARVEDESTLIKT-----------ASKRDHELQPGPPCFVYTLAFFSALGGFLFGYDTGVVSGAMLLLKRE----KKLSSVWQELLVSITVGAAAVSALAGGFLNGRFGRRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPPDLRGQLVTVNTLFITGGQFIASVVDGAFSYLPHDGWRFMLGLSVVPAALQFLGFLFLPESPRWLLQKGFTQNALLVLRQIRGDVDVEEEFESIRCSIQEEQ--RDV-AGGPVLWRMLASPPARRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFCYGLNATAVVQSSCVPVDPANTETAALGRCFNGTQ-KASSVFWAYNYCPTPYSWVVLLGLILYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVFVSGCLPETKGLRLEEIESLFSRRLCSCGAHTDQYMRRLEFGALHYATSEPEGRISYISVSTSQKKTKSLILISVLFHSRKNIEHNIFVLPLHFEFTEEVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04162-1", "uniprot_id": "YD387_YEAST", "id": "Q04162-1", "name": "Probable metabolite transport protein YDR387C", "aln": "-------------------MSTDESED-------------VYSDLYSIISQVTS----------NTANDIEQLPYALTFKTSLIFVGATIGGLLFGYDTGVISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVSYVIASLMKEIDN-SWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTYHVNSKIKQLIIELDKLR-------------LYEDASEPLLVQS-QSVIRYMDSSTSGTLSPPNIKRLSSNTER----TSNTMSSSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKFNIKNPLLPPILIASTN-FIFTFFAMYTMDS-----------LGRRAILLRTILIMTVGLLLCSVGFGHDQVNLLLISVVIYVAAYASAMGSVPWTC-VEFLPLNRRSFGASCIACTNWLTNAFVSMTYLSTINTIGDENTMLIFAFFTVCAWFFVYFWYPEVKGLSLEEVGRVFDN----------------------------GIDVHYVFRTYH--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : : : . . . :::**:********:**.:* *: : * : :**:.* : .: ..:: . * . *** : :.. : .. :: * . *:.*** **:.:*::: **::::*:**. :** ::*:* : *****:.: *: . :. : : .**:::.*:.:** : : : *:****** :.** : * : . ..*: * * : : : ..* * . .::: : . .: ...* ::*. : : :: : :: :* * :. .: . : :: ::. ::: * : :* . . :: . * : : .::* . . . : . . *:.:::*:. :*..**.:*** *: ** ** * :* : **: *.:**:*:* . : : .:::::* :: . .*: **.** ***: :*.. : *: . ", "identical_positions": 107, "similar_positions": 191, "identity": "15.4%" }, { "cls_id": "homologset.agr.SGD:S000002796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBW5-1", "uniprot_id": "BIN2_HUMAN", "id": "Q9UBW5-1", "name": "Bridging integrator 2", "aln": "MAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSS---RRSLVISPPVRTATVSSPLTSP------TSPSTLSLKSESES-----------VSATEDLAPD--------------AAQGEDNSEIKELLEEE------------EIEKEGSEASSSE----------------------------------------EDEPLPACNGPAQAQPSPTTERAKS------------------------QEEVLPSSTTPSPGGALSPSGQ-PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEA-KENEN-IHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQ-LQVSMVPENNNLTAPEPQEEVSTSENPQL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49418-1", "uniprot_id": "AMPH_HUMAN", "id": "P49418-1", "name": "Amphiphysin", "aln": "MADIKTG----IFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQ-KPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39743-1", "uniprot_id": "RV167_YEAST", "id": "P39743-1", "name": "Reduced viability upon starvation protein 167", "aln": "-----------MSFKGFTKAVSRAPQSFRQKFKMGEQTEDPVYEDAERRFQELEQETKKLSEESKRYSTAVNGMLTHQIGFAKSMEEIFKPISGKMSDPNATIPEDNPQGIEASEQYRAIVAELQETLKPDLALVEEKIVTPCQELLKIITYIRKMATKRNHKKLD-------------LDRHLNTYNKHEKKKEPTAKDEERLYKAQAQVEVAQQEYDYYNDLLKT---QLPILFSLEAEFVKPLFVSFYFMQLN----IFYTLYNRLQDMKIP---------------------------------------------------------------YFDLNSDIVES----------------YIAKKGNVEEQTD-----------------------------------------ALTITHFKLGYSKAKLEMTRRKYG----------------------------VATAEGSPVSGASSGVGY---GAGYDPATATSPTPTGYGYGAAAPSYAAQPAAQYGTAAAVGTAAAVGTAAGAAAGAVPGTYPQYAAAQSPPLTGLGFQQSPQQQQGPPPAYSNPLTSPVAGTPAAAVAAAPGVETVTALYDYQAQAAGDLSFPAGAVIEIVQR----TPDVNEWWTG--------RYNGQQGVFPGNYVQLNKN------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * ..** :.. **: . :*:* :*: .* . : * :* .: : : :*:: * . .::::.*::.. .: : : : : :: : ::. ::::*.. ::*:. : ::: : :. *: * : :: * . :: * . . . :::. . ::.:: :: .* :. . *. . . . . :. :.:: * : *. . : . : :. : . *: . . : * .: * . .. . . :. .: . * .:. : . ..* :. . . : : : .. . : . :.: .* :. . * .:. ", "identical_positions": 32, "similar_positions": 156, "identity": "4.57%" }, { "cls_id": "homologset.agr.SGD:S000002797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGF1-1", "uniprot_id": "RHG29_MOUSE", "id": "Q8CGF1-1", "name": "Rho GTPase-activating protein 29", "aln": "MIAHKQKKAKK---------------------KRVWASGQPSAAITTSEMGLKSVSSSSSFDPEYIKELVNDVRKFSHMLLYLKEAILS----DCFKEVIHIRLDELLRVLKSILSKHQNLSSVDLQSAAEVLTAKVKAVNFTEVNEENKNDIFREVFSSIETLAFTFGNILTNFLMGDVGSDSILRLPISRESKSFENISVDS--------VDLPHEKGNFSPIELDNLLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATR-SSIGIQEFMPLQSLFTNALLSDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKDLWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLAKNLNKQLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVK---------------ATSSSELEEKVDGNVNKQMTNSPQTSGYEPADSLE-DVAR------LPDSCHKLEEDRCSNSADMTGP---SFVRSWKFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPS----EAGP--------NSLGAFKKTLMSKAALTHKFRKLRSPTKCRDCDGIVMFPGVECEECLLVCHRKCLENLVIICGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEVNRILLKSKDLLRQLPASHFNSLHYLIAHLRRVVDHAEENKMNSKNLGVIFGPTLIRPR---PTTAPVTISSLAEYSNQARLVEFLITYSQKIFDGSLQPQAVVISNTGAVAPQVDQGYLPKPLLSPDERDTDHSMKPLFFSSKEDIRSSDCESKSFELTTSFEESERRQNALGKCDAPLLDNKVHLLFDQEHESASQKMEDVCKSPKLLLLKSNRAANSVQRHTPRTKMRPVSLPVDRLLLLASSPTERSSRDVGNVDSDKFGKNPAFEGLHRKDNSNTTRSKVNGFDQQNVQKSWDTQYVRNNFTAKTTMIVP-------SAYPEKGLTVNTGNNRDHPG-----SKAHAEPARAAGDVS-----------ERRSSDSCPATAVRAPRTLQPQHWTTFYKPPNPTFS------VRGTEEKTALPSIAVPPVLVHAPQIHVTKSDPD-------SEATLACPVQTS--GQPKESSEEPALPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQJ5-1", "uniprot_id": "RHG29_RAT", "id": "Q5PQJ5-1", "name": "Rho GTPase-activating protein 29", "aln": "MIAHKQKKAKK---------------------KRVWASGQLSAAITTSEMGLKSVSSNSIFDPEYIKELVNDIRKFSHVLLYLKEAILS----DCFKEVIHIRLDELL-----HMSKHQNLNSVDLQNAAETLASKVKAVNFTEVNDENKNDLFREVFSSIETLAFTFGNILTNFLMGDVGNDSILRLPISRESKSFENISMDS--------VDLPHEKGNFSPIELDNLLLKNSDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATR-SSIGIQEFMPLQSLFTNALLNDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLGKNLNKLLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVK---------------ATSSSELEEKVDGNVNKQIASSPQTSGYEPADSLE-DVAR------LPDSCHKLEEDRCSNSADMTGP---SFIRSWKFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPS----EAGP--------NSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVMFPGVECEECLLVCHRKCLENLVIVCGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIESRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEINRILLRSKDLLRQLPASNFNSLHYLIVHLKRVVDHAEENKMNSKNLGVIFGPTLIRPR---PTTAPVTISSLAEYSSQARVVEFLITYAQKIFDGSLQPQAGVIANTGAIAPQVDHGCHPKPLLSPDERDSDHSLKQLFFSSKEDIRTMDCESKTFELTTSFEESERKQNALGKCDAPILDNKVHLLFDQELESASHKTEDTCKSPKLLLLRSDRVANSVQRPTPRTRLRPVSLPVDRLLLLAGSPTERSSRNTGNTDSDKFGKNAAFEGLHRKDNSNTTCSKVNGFDQQNVQKSWDKQNERNSFTAKTTVIIP-------SAYAEKGLAVSTGNNRGHSSGAAQPSKAHADPARSARDTS-----------EHSSSDSCPVAAVRAPRTLQPQHWTTFYKPPNPTFN------VRGTEEKTAFPSAAVPPVLVHAPQSHVAKSDPD-------LEATLACPVQTS--GQPKESSEEPGLPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52LW3-1", "uniprot_id": "RHG29_HUMAN", "id": "Q52LW3-1", "name": "Rho GTPase-activating protein 29", "aln": "MIAHKQKKTKK---------------------KRAWASGQLSTDITTSEMGLKSLSSNSIFDPDYIKELVNDIRKFSHMLLYLKEAIFS----DCFKEVIHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEVNEENKNDLFQEVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENVSVES--------VDSSSEKGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNMVKLAEATR-TNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLAKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTLVFQCDLTLKAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVK---------------ATNSTE-EEKVDGNVNKHLNSS-QPSGFGPANSLE-DVVR------LPDSSNKIEEDRCSNSADITGP---SFIRSWTFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPS----ETGP--------NSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPR---PTTAPITISSLAEYSNQARLVEFLITYSQKIFDGSLQPQDVMCSIG-----VVDQGCFPKPLLSPEERDIERSMKSLFFSSKEDIHTSESESKIFERATSFEESERKQNALGKCDACLSD-KAQLLLDQEAESASQKIED-GKTPKPLSLKSDRSTNNVERHTPRTKIRPVSLPVDR-LLLASPPNERNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNGFDQQTLQKIQDKQYEQNSLTAKTTMIMP-------SALQEKGVTTSLQISGDHSINATQPSKPYAEPVRSVREAS-----------ERRSSDSYPLAPVRAPRTLQPQHWTTFYKPHAPIIS------IRGNEEKPASPSAAVPPGTDHDPHGLVVKSMPD-------PDKASACPGQAT--GQPKEDSEELGLPDVNPMCQRPRLKRMQQFEDLEGEIPQFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PCS4-1", "uniprot_id": "RHG29_DANRE", "id": "Q6PCS4-1", "name": "Rho GTPase-activating protein 29", "aln": "MFRQGSNSGNKRMTSGARLSQPIIPLSLPTASSKTLEMGRSSKTNPLNAMGLDHNIATSGGDPEYIMQLVNDVRKFSDVLLSLKEAFHSKESQECSQHVVNERLGELVHVLKAVIGKHQALNSSEILGAAGTVIAKVKGVNFKEVNNENKSTIFGEIHTSIDTLAFTFGNVVSDFLMGDVDGGSRLGYPQARRSRSFENLSEDSRGCSQNDLADHSLSPELSTVEQVDLLLLKNDSGVESALLYAKAWSKYTKDVLAWVEKRLSLDMECAKSFAKMAESAK-AVASQQDFMPFRDIYVSAFKNEIEYNHVLLQTAAALQTNKFTQPLLARKNDLDKQRKEIKEQWQRELKKMNESESALKKARLLKMQKREEYEKARSSTSRTEEEQPAAG-------GRTLEKKRRVEEEALQKAEEAQEQYKACVADLEAKKVSLSNAKSEILAQIRKLVFQCDLTLKAVTVNWFQMQQAQTMPLSVNYQALSEQAKKYEPGQRYSEFVRSLPKERVWLESLSQDITASSKTGMSLHKRSQNSTRSSHGNLSQGSATSMD-NHSADEVEGNMQPCKAKIAERRSNSSIDMQVPRTQGSQRAWSSGSAGGGGMCSDSESAGGSSESRSMDSPTASPGDFKRRLPRTPSTGTMSSADDLDEREPPSPS----DTGLSEMVMETASSPGPFRNAQMSKAAHTHKLRKLRAPSKCRECDSLVVFHGAECEECSLACHKKCLETLAIQCGHKKLQGRLHLFGIDFAQVVKNSPDGIPFIIKKCTSEIESRALTIKGIYRVNGAKSRVEKLCQAFENGKDLVELSDLHPHDISNVLKLYLRQLPEPLILYRYYNDVIGLAKETQNMDKTDSAKEKSAGEQLG--LSTELKRVLFKVRDLLRQLPAPHYKTLQFLITHLHRVSEQAEENKMTASNLGIIFGPTLIKPR---HLEAEVSLSSLVDYPHQARMVELLIKHHQMIFDVPLSPMSPTS-------PTVSQASFGSSIQDKESKLSRHSRS--LMDIKESAKLYKRHSSVIIPAQLMEEGKEMKTGDHRVQTSGEGSDVNGVGLTSVDSTSVFNRP-GASSRMVQLRPQR---------AKPVSRPISMPIDR--LLN----ERNSRNTVEHDHSPAAIEETTEPEKPTTPRHTNFYRNPFIDTQTLRRTWDRQYRHYDVTPRTAMIVANLPPSGVQKQPEISMASQSSTSRKDGTSQSGVAPISFRAARTLKPSSPGTFYRPPSGGQLKPSDLLAKSVSRAPTTTTGAIYTTAITVLTTASTSSVMTISTAVTTPPTTPTTSVTVALTSKPTFTTVSRSVSGGAGEGLSESDLLSPVTLSPPQSPGSSTEELSPTDAKPLYQR-RSRRMQELEHREAHFV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9P107-1", "uniprot_id": "GMIP_HUMAN", "id": "Q9P107-1", "name": "GEM-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATVTNEASCWS--------GPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGK-VSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKR-DYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAPQASPGP------SKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVR---------------ALRPEAPPPPPPAFSFQEFLPSLNSSPLDIRKKLSG------------PLPPRLDENSAEPGPWEDPG------TGWRWQGTPGPTPGSDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTES-SDDFEERDPDLGDGLEN------------GLGSPFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVS-GTECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPS------------PEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELP----------------------QATEPPPQDSSPAPGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEVS----------------------------------------------------------SQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVAS--------------------------------------KLCEETPITSVPRGS------------LRGRGPSPAAASPEGSPLRRTPLPKHFEITQETAR------LLSKLDSEAVPRATCCPDVQPEEAEDHL-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17121-1", "uniprot_id": "SAC7_YEAST", "id": "P17121-1", "name": "GTPase-activating protein SAC7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNNTLKQGSKIENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTSLSRNAQPTTLKRPPLSSRPYSYNTPTKDRKSFSKSAKQNNNNNNANSGTSPHAEFKNYRDMFLSNRNGFTGRVFGVTLAESLSVASAEVIVQSELVSFGRIPIVVAKCGAYLKANG----------LETSGIFRIAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLN---------------------NLAEPLIPLSLYEQFRNPLRSRPRILR-------------------------------------------------------------------------------------------------------------------HMLTHEVSHPNANKTNNVTVKSSRQNYNDDGANDGDIEKED---------------------------AKDDEEKRRRKIR--------------------------HKRRLT--------RDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQ-----SQFNLMSGRNLAAIFQPSILSHPQHDMDPKE---YELSRLVVEFLIEY-----SYKLLPHLLKLAKREQQERLSTENKKNNGD----------------KQKTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPIS-------------------------------------------------------------------------TSIPENSSDLQTSKMLKPPKQRRPHSKSFGSTPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLTATEAEGDDYE-------------------------------------------------------------EENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTN--------------------------------------------SSFNTRPISMILTSG---------------NDNSADQLELLSNTHSNNERSNALPLTEDDGD---------ERNSRSRKRESWFQRLTSRSGSANRA------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . :: . . : *:.: :. . :: .:. .::. : . : . :. : . .* :. : .: : : :: *.: .. . . : . * . . * :* . : : . . . . :: : :: . .*. :* : .::: : : *. . . *: *. :: : . :. :: *::* *:: * : : . : * : .. : ::: : . . : : * . . . :.: :: . :::. :: :* : :: .: *** : . . : ::* . :: . :**: ..*. : . . : . .. . . . . :. . : : : . . . . . .. : : ", "identical_positions": 25, "similar_positions": 171, "identity": "1.81%" }, { "cls_id": "homologset.agr.SGD:S000002798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A3Z5-1", "uniprot_id": "A0A8I6A3Z5_RAT", "id": "A0A8I6A3Z5-1", "name": "SUMO-activating enzyme subunit 2", "aln": "--------------------------------------------------IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEEANAD-QQSEPQLGLKDQQVLDVKSYASLFSKSIETLRVRLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDT--------PEKVGPKQAEDAAKSIANGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEGP------SNSADGSRDDRT-RKRK-------------LEENEGAST-----KKSRLEQV---EDQDDVIALD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1F9-1", "uniprot_id": "SAE2_MOUSE", "id": "Q9Z1F9-1", "name": "SUMO-activating enzyme subunit 2", "aln": "----MALSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGE-ANAD-QQNEPQLGLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDS--------PEKVGPKQAEDAAKSIANGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEGP------SNSTDCSGDDKA-RKRK-------------LEENEAAST-----KKCRLEQM---EDPDDVIALD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBT2-1", "uniprot_id": "SAE2_HUMAN", "id": "Q9UBT2-1", "name": "SUMO-activating enzyme subunit 2", "aln": "----MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDA--------PEKVGPKQAEDAAKSITNGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEDS------SNNADVSEEERS-RKRK-------------LDEKENLSA-----KRSRIEQK---EELDDVIALD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXG4-1", "uniprot_id": "SAE2_DANRE", "id": "Q7SXG4-1", "name": "SUMO-activating enzyme subunit 2", "aln": "---MAELVGPLRKQLADSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDTADPEAA------------------WNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKKRKAPLPLEWEEINQLGS------QEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFSMNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKIL-------NSDFEQCRTIFLNKQPNPRKKLLVP-CALDPPNASCYVCASKPEVTVKLNVHKTMVQALQDKILKEKFGMVAP-DVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDA--------PDKAPAPSAPEEGKNIANGNKDS------AQPSTSSK------AAVEDDDVLLVDSDEEPS------SSTMDTESSNRK-RKHH-------------DAETDDASS-----KRKRLDQQPADDDDEDIIALD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUA4-1", "uniprot_id": "Q7KUA4_DROME", "id": "Q7KUA4-1", "name": "SUMO-activating enzyme subunit", "aln": "--MAAAINGVFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAK-HLFNQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQWAKDCNYDAGKLFNK----------FFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGS------SGDQKDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVL-------EAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNP-DVTVQS-NGSILISSEEGETECNDGKLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKEDEPKSAKKRSTNGEGDSKDDGPSTSKRSRPNEVVEEDDDDCLVIEEDEDQADVVVVATDKLSVQSPPKSGSKRKPCEVIEDEDITEILESSDDEPAGPTKCKRSRLDDS----NPVAVISID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52488-1", "uniprot_id": "UBA2_YEAST", "id": "P52488-1", "name": "Ubiquitin-activating enzyme E1-like", "aln": "MPRETSLVTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAVQHFNNSKLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPKTFPVCTIRSTPSQPIHCIVWAKNFLFNQLFASETSGNEDDNNQD-----------------------WGTDDAEEIKRIKQETNELYELQKIIISRDASRIPEILN-K----------LFIQDINKLLAIENLWKTRTKPVPLSDSQIN-----------TPTKTAQSASNSVGTIQEQISNFINITQKLMDRYPKEQN--HIEFDKDDADTLEFVATAANIRSHIFNIPMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRVLNLLKYAPTTKYTDLNMAFTAKASNLSQNRYLSNPKLAPPNKNCPVCSKVCRGVIKLSSDCLNKMKLSDFVVLIREKYSYPQDISLLDASNQRLLFDYD--FEDLNDRTLSEINLGNGSIILFSDEEGDTMIRKAIELFLDVDDELPCNTCSLP--------DVEVPLIKANNSPSKNEEEEKNEKG----ADVVAT-------TNSHGKDGIVILDDDEGE----------ITIDAEPINGSKKRP----------VDTEISEAPSN-----KRTKLVNEP---TNSDIVELD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :******:*********:::.: :.*: .* ::. * . : : : . : :.:*.:* :::.**** ***.:**::. .:*********: * : * * *:*:** * . ::** ****.***:********* .******... .:: . : . . .:: .:.. ::. . . * * :* :** ** :.:**:.*. *:*:. : :.* :: * : : * . : . : :**** :::**::.:*:* ::*.: ** *::*.:*************: ** : .:::* . : . : .* :: :. * ** .* **:. .:::. . * * :: * *: : . .. *: . : * : : **::.: :* : .* : : : .: :. . . : . : .. : . : :: .*. ::::.** . *:: .: . *: :: : :: :*", "identical_positions": 137, "similar_positions": 189, "identity": "18.72%" }, { "cls_id": "homologset.agr.SGD:S000002800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75486-1", "uniprot_id": "SUPT3_HUMAN", "id": "O75486-1", "name": "Transcription initiation protein SPT3 homolog", "aln": "-----------------MNNTAAS-------PMSTATSSSGRSTGKSISFATELQSMMYSLGDARR-PLHETAVLVEDVVHT---------------QLINLLQQAAEVSQLRG-ARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVK--------------GIDEDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDD----------------EIDEVKQERMERAERQTRIMDSAQYAEFCESRQLSFS-KKASKFRDWLD--CSSM-EIKPNVVAMEILAYLAYETVAQLVDLALLVR------QDMVTKAGDPFSHAISATFIQYHNSAESTAACGV-EAHSDAIQPCHIREAIRRYS---HRIGPLSPFT-NAYRRNGMAFLAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A991-1", "uniprot_id": "A0A8I6A991_RAT", "id": "A0A8I6A991-1", "name": "", "aln": "-----------------MNNTAAS-------PMSTATSSSGRNAGKTISFAAELQSMMFSLGDARR-PLHETAVLVEDVVHT---------------QLINLLQQAAEVSQLRG-ARVISAEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIIK--------------GIDEDDLLEEKLSGSSGTNKRQKIAQDLINSIDQTGELLAMFEDN----------------ELDDVKQERMERAERQTRTMDSAQYAEFCESRQLSFS-KKASKFRDWLD--CSSM-EIKPNVIAMEILAYLAYETVAQLVDLALLVR------QDMVSKAGDPFSHAISATFIQYHNSAESTAACGV-EAHSDAIQPCHIREAIRRYG---HKIGPLSPFT-SAYRRSGTAFLAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06844-1", "uniprot_id": "SPT3_YEAST", "id": "P06844-1", "name": "SAGA complex subunit SPT3", "aln": "-------------------------------------------MMDKHKYRVEIQQMMFVSGEIND-PPVETTSLIEDIVRG---------------QVIEILLQSNKTAHLRG-SRSILPEDVIFLIRHDKAKVNRLRTYLSWKDLRKNAKDQDASAGVASGTGNPGAGGEDDLKKAGGGEKDEKDGGNMMKVKKSQIKLPWELQFMFNEHPLENNDDNDDMDEDEREANIVTLKRLKMADDRTRNMTKEEYVHWSDCRQASFTFRKNKRFKDWSG--ISQLTEGKPHDDVIDILGFLTFEIVCSLTETALKIKQREQVLQTQKDKSQQSSQDNTNFEFASSTLHRKKRLFDGP-ENVINPLKPRHIEEAWRVLQTIDMRHRALTNFK-GGRLSSKPIIM--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VGE2-1", "uniprot_id": "SPT3_DROME", "id": "Q9VGE2-1", "name": "SAGA complex subunit Spt3", "aln": "MNYNAKRVMRQNSVCVGSNDMAASPIMIGPAPPSAPSTPQLQTTEDIKPLLVQRQVILLQSGSIPTNPSPQQINLAGHNVAGGASGSNVANVLIPDDAPVSLLTEIADIMRSFGDSDQPRTGSVKLVEQILQQQLRGIFNEASLVAMRRKQNP-----------CPSQADFEFLMRNHPVKIARMRKHLKDMRILKRFLSIRTGRPQDFMDDLEQQEEDEELAIDVYELHDEDRMRRLFRADRISQILTGQQYLEFNEARKTSFYCRHGEKIKNKFRRFLDLPADLRIPTPTMNILAYLAHETIAAIVDYSILTR------LNSDNRATEPYSRVTSAGGSPAMMHVCPEVTQGRGMEVVKPISVPEIHEAMRRFR--QMSSRKIGRYRNSCDIDFRRSFLAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * :: *. * : * . * :.:* : . : * : . .: :: : : ::. : . : : . : :.. .. : : :. * :. : .*: *: :: : :* .: :.*: ** :: .:::: . : : .::**.:*:.* :. :.: :: : :: :. . . * ..:. .*.** * : : . :: ", "identical_positions": 23, "similar_positions": 97, "identity": "5.71%" }, { "cls_id": "homologset.agr.SGD:S000002802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63570-1", "uniprot_id": "PRS6B_RAT", "id": "Q63570-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKIQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54775-1", "uniprot_id": "PRS6B_MOUSE", "id": "P54775-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKIQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43686-1", "uniprot_id": "PRS6B_HUMAN", "id": "P43686-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKAQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R1D0-1", "uniprot_id": "B0R1D0_DANRE", "id": "B0R1D0-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-DGGVLVEKPQDDVPALL-----NSRPQTGLSFLAPEPEDLEDLYSIYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVLYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLVFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQEAGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V405-1", "uniprot_id": "Q9V405_DROME", "id": "Q9V405-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-MPYNMDVLIPE-KDELSDLK-----LKDAHSSLDEL-----DMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKNNIKKD--EQEHEFYK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH79-1", "uniprot_id": "Q9VH79_DROME", "id": "Q9VH79-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-MR-----LLKEEIAQFHEQS-----LEKYDG---------LDPHDLYVLYKKLQMELELIQVQEDYIKEEQRNLKKEFIHAQEEVKRIKAVPLVIGQFLEAVDENNGIVASTTGSNYYVRVLSTIDREQLKPSSSVGLHKQSNCLVDLVPPEADSTISMLSPDEKPDISYSDIGGLDIQKQEIREAVELPLTHAQLYKQIGIDPPRGVLLFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDLFRLAKQNSPSIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDETTNIKVIMATNRADTLDPALLRPGRLDRKIELP-LPDRRQKRLVFTTITSKMNVGEDVDLEDIIARPDKISNADINAICQEAGMHAVRENRYVVNAKDFEKGYKTSVRKD--EAQHEFYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33298-1", "uniprot_id": "PRS6B_YEAST", "id": "P33298-1", "name": "26S proteasome regulatory subunit 6B homolog", "aln": "MEELGIVTPVEKAVEEKPAVKSYASLLAQLNGTVNNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . *:* ***: *:: :**:***:**::**:* :********:::*********.:*:*..**.**** .* **:***:*** ***. **.**::**.***::**::**:* :: ::***: *:*:**:*:****:********.: :**:***********::**** *****.****: *.*:**** *****:************:****::*:*:******:*:***********:********:***.******:..*:***************************:* * ***::**:* **:***.:. :.**:. : * *.:*.* * :* **:*: ***:***:: .*:*:.* . ::.* :.:**.", "identical_positions": 241, "similar_positions": 106, "identity": "56.31%" }, { "cls_id": "homologset.agr.SGD:S000002803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE96-1", "uniprot_id": "D4AE96_RAT", "id": "D4AE96-1", "name": "", "aln": "-MDPNTIIEALRGTMDP--ALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPG-DISPYTIPEEDRHCIRENIVEAIIHSPE--LIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVS-KEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEK-QYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKD--QMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGP------DEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHS--LTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDM-EQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDDAEDDDETEELGSDEDD-IDEDGQEYLEILAKQAG------------EDGDDEDWEEDD----AEETALEGYSTIIDDEDNP--VDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRR-AAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPL8-1", "uniprot_id": "IPO7_MOUSE", "id": "Q9EPL8-1", "name": "Importin-7", "aln": "-MDPNTIIEALRGTMDP--ALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPG-DIAPYTIPEEDRHCIRENIVEAIIHSPE--LIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVS-KEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEK-QYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKD--QMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGP------DEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHS--LTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDM-EQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDEDAEDDDETEELGSDEDD-IDEDGQEYLEILAKQAG------------EDGDDEDWEEDD----AEETALEGYSTIIDDEDNP--VDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRR-AAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95373-1", "uniprot_id": "IPO7_HUMAN", "id": "O95373-1", "name": "Importin-7", "aln": "-MDPNTIIEALRGTMDP--ALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPG-DISPYTIPEEDRHCIRENIVEAIIHSPE--LIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVS-KEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEK-QYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKD--QMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGP------DEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHS--LTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDM-EQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDD-IDEDGQEYLEILAKQAG------------EDGDDEDWEEDD----AEETALEGYSTIIDDEDNP--VDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRR-AAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TMY7-1", "uniprot_id": "IPO8_MOUSE", "id": "Q7TMY7-1", "name": "Importin-8", "aln": "-MDLNRIIQALKGTIDP--KLRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPD--LVRVQLTMCLRVIIRHDFPGHWPAVVDKIDYYLQSPNSGSWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYSVLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQK-EYIAPRVLQQAFNYLNQGVVHAVTWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKD--QIELFLQNHVFPLLMSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDEEMPVKVEAALALQSLISNQAQAKEHMKPYVRFIMQELLHIVRETENDDVTNVIQKLICEYSQDVASIAVDTTQHLAEIFGKVLQSD-------EYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVIEFYEEILSLAYN--LTCHTISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGEAGEDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLEQVQLPHNPGPVTSQFINQWMNDTDYFLGHHDRKMCIIGLSVLLEL-QNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEKVDIEENEEISSEEEEETSVSAQAMQSQIGRSE--------------EEDDDDWDEEV----LEETALEGFSTPLD-LDNS--VDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAAGQFHI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6J6-1", "uniprot_id": "A0A0G2K6J6_RAT", "id": "A0A0G2K6J6-1", "name": "", "aln": "-MDLNRIIQALKGTIDP--KLRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPD--LVRVQLTMCLRVIIRHDFPGHWPAVVDKIDYYLKSPNSGNWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYSVLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDDRPELVWWKCKKWALHIVTRLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQK-EYIAPRVLQQALNYLNQGVVHAVTWKQMKPHMQNISEDVIFSVMCYKDEDEELWQEDPYEYIRVKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKD--QIELFLQNHVFPLILSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDLEMPVKVEAALALQSLISNQTQAKEYMKPYVRFIMQELLHIVKETESDDVTNVIQKLICEYSHDMASIAVDITQHLAEIFGKVLQSD-------EYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVIEFYEEILSLAYN--LTCHAISPQMWQLLGILFEVFQQDCFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGESGEDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLERVQLPHNPGPVTSQFINQWMSDTDYFLGHHDRKMCIIGLSVLLEL-QNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEKADIEENEEISSEEEEETSVNAQAMQSQICRGE--------------EEEDDDWDEEV----VEETALEGFSTPLD-LDNS--VDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAG-QFHI---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15397-1", "uniprot_id": "IPO8_HUMAN", "id": "O15397-1", "name": "Importin-8", "aln": "-MDLNRIIQALKGTIDP--KLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPD--LVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQK-EYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKD--QMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSD-------EYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYS--LTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLEL-QNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEE-TNVTAQAMQSNNGRGED------------EEEEDDDWDEEV----LEETALEGFSTPLD-LDNS--VDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSD6-1", "uniprot_id": "Q9VSD6_DROME", "id": "Q9VSD6-1", "name": "", "aln": "-MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVMQTTVEQPVRQAGAVYLKNLINSSWSDHEAKPG-EPIPFSIHEQDRAMIRGAIVDAIVHAPE--LIRVQLSVCVNHIIKSDFPGRWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTYEYKRHEERTPLNEAMNLLLPMIYQLMVRLLAEQSEQSVLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVP-DSSHLDDDERTEFPYWKTKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPTFSQGVLEVLLKILDQYRNR-VYVSPRVLTDVLNYLKNAVSHAYTWKLIKPHMVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKRKGILPKAMATIMQIITSPNADNKQKDGALHMIGTLADVLLKKASYRD--QVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFSQVLESE---------EGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNITDFYEETFSLVYD--LTAKAISPEMWQMLELIYQVFKKDGIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPGEDPECHAAKLMEVIILQCKG-QIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNN-DSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRK-AAKESKLIEKQGGFAFPQTAVPTSFKFGS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04175-1", "uniprot_id": "SXM1_YEAST", "id": "Q04175-1", "name": "Importin beta SMX1", "aln": "MVQEQAILSCIEQTMVADAKIIKEAEQQLFEFQKQPGFTSFLLNIVSDDNFALNVRLSSAIYLKNKIHRSWDTKR--------EDGIKADEKLSIKERLIETLVKNCENNHIRPILTETINGILVGQEDWDLAPIIKNL---LSSGDASYIYPGLLLLFQLCKAHRWDMVGSRDYIDSVIEELFPIVEGIASNIGSQTDYRSNEILYLILKSFKYACLNNLPQYFSQPERIMSWVQLHLYLCSKPLPVEVMELDPADRSLDKRVKVNKWGFGNLNRFLQRYN---KITKAITKEFIDYIFNTIVPIILREFFKDIEAWGNNSLWLSDSSLYFLISFLEKCVTIDQLYPLIEPHLQIIFENVIFPCLCANEQSIELLEDDQEEYTRRYFDINREGSTPDAASADFIFLIGSKRPEKLNNILPFINDIFTRFDANSSDINMAFKEEGALRTLSNLFSFIDEPSVLENIFGHFIVPLLSQDKYMFLVARSLETIALYSEEFKDMNILSQLFELTYTNFLNSNVLPVQIEAADAIKCLIVSNPQIHPAVSAHVPGMMEKLLKLSKIFEIDILSEVMEALVERFSDELSPFAKDLASNLVEQFLRIAQALVENPSETYSASDQEQEIQASGLLQTMTTMVMSMN-KVPLIESLAPVVKFVVLHAQISFITEAVDLLDALTISSHLLYNQIAPPIWELLHDILDSFQTYAMDYFEAYSIFFETIVMTG---FPQDQTYVQPLLEILSAKLESEVDYDIEHVMQILMYFALS-------MRDIPLFSKAIKVSTNDELGLD--SKCIVKLGLANLFAKPIETLQIMENEG-------FTINFFTNWFN--EKFYSVFAIKLQVLVILTLLKM-PEVPNSVSPLLNNLTNKLVELTLSLPKAIRNRDAVTEGKSLEGDLTPEEEEEYFIECDDD----------------------------------------------MKETVLDQIN-------------VFQEVHTFFKNLQNEDAGKYEKIINYLDESKRDSLQVILEFVSQH-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : . :. *: . ** :* : * .*.. :*.* . . ** :..:**** : * :. * ::: *: ::: ::: : :* *: :. *: : . ::..: *.. . *: ::** * :.:. .* : .:: ::* : .: .: . * : *:* : ** : : : *::: : .: :* : .:: :*. * :**.: : *:::**. :: :* : : : : . ::* : : :. ::: * :.:::: * : ::**: : ::***. :. .: . ** :.* ** * **: .: :* .*: ::. .** * : : :*:* : : . : *:: *:* : : :* :: .:.* : . : . . : . :::. * ..*: :: . :**::*** .:: :* .: : : . : : : ** : : * : :::*:: :: ::.:: ..* : .:*. * :: :: ::: : * .:*:*: *:: :: : : .* : :: : : : :*. . * : ::* :*::* : : *: ::** :.. * . : .: . : : : * . . * * *: . : * :* : . : . . ::: :* *: .* : ::. .: :*:.:*: : * . . *: :: : *:.: * :. : :: :: * .* :. : . . . : :* . : : :** *: . : . : :. .: * : * .: ** : ..:: ", "identical_positions": 124, "similar_positions": 343, "identity": "11.51%" }, { "cls_id": "homologset.agr.SGD:S000002805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01658-1", "uniprot_id": "NC2B_HUMAN", "id": "Q01658-1", "name": "Protein Dr1", "aln": "MASS-------SGNDDDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WV0-1", "uniprot_id": "NC2B_MOUSE", "id": "Q91WV0-1", "name": "Protein Dr1", "aln": "MASS-------SGNDDDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASTQAGSSQDEEDDDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI68-1", "uniprot_id": "NC2B_RAT", "id": "Q5XI68-1", "name": "Protein Dr1", "aln": "MASS-------SGNDDDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEDDDDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VJQ5-1", "uniprot_id": "NC2B_DROME", "id": "Q9VJQ5-1", "name": "Protein Dr1", "aln": "MSNPQEELLPPSAEDDELTLPRASINKIIKELVPT-VRVANESRELILNCCSEFIHLISSEANEVCNMRNKKTINAEHVLEALERLGFHDYKQEAEAVLHDCKEVAAKRRRQSTRLENLGIPEEELLRQQQELFAKAREEQAREEQQQWMSMQAAAMVQRPPLADGSVASKPSEDDDDDDDDDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q92317-1", "uniprot_id": "NCB2_YEAST", "id": "Q92317-1", "name": "Negative cofactor 2 complex subunit beta", "aln": "----------MAGDSDNVSLPKATVQKMISEILDQDLMFTKDAREIIINSGIEFIMILSSMASEMADNEAKKTIAPEHVIKALEELEYNEFIPFLEEILLNFKGSQKVKETRDSKFKKSGLSEEELLRQQEELFRQSRSR----------------------LHHNSVSDPVKSEDSS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:.*::::*:*:::*:*.* : : .::::**:::*. *** ::** *.*:.: **** .***::*** * : .: : :* : * :. .::::: *:.********:*** ::*.. *.: ..:.. ", "identical_positions": 43, "similar_positions": 62, "identity": "23.37%" }, { "cls_id": "homologset.agr.SGD:S000002806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V920-1", "uniprot_id": "G3V920_RAT", "id": "G3V920-1", "name": "WD repeat-containing protein 43", "aln": "MAAGGGGSCDPLAPAGVPCAFSPDSQAYFALASSDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESHQRKKRKSEAIGTNDQADLLALGTAVGSILLYSTVKGELHSKLISGGHEKRVNCIQWHQDNDCLYSCSDDKYIVEWSTQMCRVKCKWKGD-NSSVSSLCISPDGK---MLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLRFTTIRP-NESQPFDGVTGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHVLNGHCKKPLTS-----NCTIQVATPGKGKKATPKPIP---ILAAGFCLDKMS---LLLVYGSWFQPTIERLALNSKDTHICLERDISNCWAPTVETAITKVKTPVMNSEAKVLVPGVPGHH---APIKLLPAQPKEAENKRKLGGKEATIEERLGAMDLDRRGKKDDLLQTNSFP----VLLAQGLESNDFEMLNKVLQTRNVNLIKKTVLRMPLHAVIPLLQELTKRLQGHPNSAVLMVQWLKCVLTIHASYLSTLP--DLVHQLGTLYQLMESRVKTFQKLSHLHGKLILLVTQVTASEKTKKMPSPGLKAKLVYEEESSEEESDDEIPEKDSDDNWDEDEEK-DSENDEAVDEDSEND----EAVDEEDEDREAASEKELNGDSDLDPENESEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQL4-1", "uniprot_id": "WDR43_MOUSE", "id": "Q6ZQL4-1", "name": "WD repeat-containing protein 43", "aln": "MAAGGGGSYDPLAPAGVPCAFSPDSQAYFALASSDGQLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESHQRKKRKSEVTGTKDQADLLALGTAVGSILLYSTVRGELHSKLTSGGHENRVNCIQWHQDNDCLYSCSDDKYIVEWSTQTCKVKCKWKGD-NSSVSSLCISPDGK---MLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLRFTTIRP-NESQPSDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYVDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGHCKKPLTS-----NCTIQIATPGKGKKVTPKPIP---ILAASFCLDKMS---LLLVYGNWFQPTIERVALNSKDTHICLERDISNCWAPTVETAITKVKTPVMNSEAKVLVPGIPGHH---APIKLPPAQPKEAENKRKLGSTEATIEERLGAMDLDRKGRKDD-LQTNSFA----VLLTQGLESNDFEILNKVLQTKNVNLIKRTVLRIPLRVVIPLLQELTKRLQGHPNSAALMIQWLKCVLTIHASYLSTLP--DLVEQLGTLYQLMESRVKTFQKLSNLHGKLILLVTQVTASEKSKKMTSPGQKAKLVYEEESSEEESDDEVPEKDSDDNWDEDEDK-DSEKDEGVDEDNEEEDEDMEDKEENEEDREVSSEKELNGDSDLDPENESEEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15061-1", "uniprot_id": "WDR43_HUMAN", "id": "Q15061-1", "name": "WD repeat-containing protein 43", "aln": "MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGD-NSSVSSLCISPDGK---MLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGYCKKPLTS-----NCTIQIATPGKGKKSTPKPIP---ILAAGFCSDKMS---LLLVYGSWFQPTIERVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHH---AAIKPAPPQTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFP----VLLTQGLESNDFEMLNKVLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLSTLP--DLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAE---GKDEENGEDRDTASEKELNGDSDLDPENESEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7K2-1", "uniprot_id": "A1Z7K2_DROME", "id": "A1Z7K2-1", "name": "Small-subunit processome Utp12 domain-containing protein", "aln": "MSLG----------KKHVLGFSPNGGQLFASVDESGVLRIWNTETNTLYQEFTPNLQLSGSCTALTWV---LVAGSRPKKSRKSLQAQDAAGDQLHIALGTYKGSVVIYSLAEGKISRTLSGDSHDGPVTSITNDN-AGHLYTVGADCRVVVWSLTDERSIAEWQVG-PEKPQNIVYLQKSG---TLAIGYRQLKVYDIKTKELVETFTGHSGEINTISSVASTD----------GTEFVLTTAKMERVICFWKIDKKGKNKASACTLLMEDLAYCLTSEVRDDGQ--LRVASVTRNGIIHIYLLNVNSLSAEKFVKP----KVSLQIVSDG---AETVEPLL---AVAAHFVTDSNRSHEILFGYGSRQQLQFERFTPNYGEKLNVIVRADP----KKLYAKKKGKEQPGYQAATKVQKPIVNQKN---VEYNSALPISQ------KKVQNEVPMEARLEHLKIQGTKLSGGKLLTQSKT----QLLMQALHSKDQAMIQAVLSTQDPETIQLTLDRLPLDYVNPLVNELSILLQGKHASVRSALRWLHALTSTHTSVLMSEDKEALREKLAVCLGVAEQRMHCLSEALQITGRVNLIINQMKRNADN----HLNDNKALILDEDPDE-------PDPEAETNWSDLEEDQPGSPKSPLED-------------ELVADDDLATD---DGNADADTDSDVSMD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04177-1", "uniprot_id": "UTP5_YEAST", "id": "Q04177-1", "name": "U3 small nucleolar RNA-associated protein 5", "aln": "-----------MDSPVLQSAYDPSGQ----------YLCYVTVALDKQRVGVQPTQRATSSGVDTVWNENFLYLEDSKLKVTCLKWVNLASSDTVAIILGMNNGEIWLYSVLANEVTYKFTTG---NSYEIKDIDLMGNQLWCIDSSDAFYQFDLLQFKLLQHFRINNCVQLNKLTIVPAGDSVAQLLVASHSISLIDIEEKKVVMTFPGHVSPVSTLQVI--------------TNEFFISGAEGDRFLNVYDIHSGMTKCVLVAESDIKELSHSGQADS---------IAVTTEDGSLEIFVDPLVSSSTKKRGNKSKKSSKKIQIVSKDGRKVPIYNAFINKDLLNVSWLQNATMPYFKNLQWREIPNEYTVEISLNWNNKNKSADRDLHGKDLASATNYVEGNARVTSGDNFKHVDDAIKSWERELTSLEQEQAKPPQANELLTETFGDKLESSTVARISGKKTNLKGSNLKTATTTGTVTVILSQALQSNDHSLLETVLNNRDERVIRDTIFRLKPALAVILLERLAERIARQTHRQGPLNVWVKWCLIIHGGYLVSIP--NLMSTLSSLHSTLKRRSDLLPRLLALDARLDCTINKFKTLNYEAGDIHSSEP---VVEEDEDDVEYN---EELDDAGLIEDGEESYGSEEEEEGDSDNEEEQ------KHTSSKQDGRLETEQSDGEEEAGYSDVEME", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.* . * . : *. : :.: . .* * . : . .: : ** *.: :** .:: .: . . . *: . . . :. : .:: . . ..: . * . : :.: :: *:: *.** :.:: :.:: * :*.: .:.: . .: . : : . :* . .:* :.:: : . . : . . .:*:.: . :.: : . : : : : . : ..: * : * . * : . . : . . . : . : :. . * * : . :* *.*.*:* ::: **..:: . *: *: *: *::.*: : : *:: * . * : * *. : * . : . : .:: :.:.. . : :*: .: : : .: *:. .. .. :. . . : : ... : .: . :", "identical_positions": 46, "similar_positions": 198, "identity": "6.53%" }, { "cls_id": "homologset.agr.SGD:S000002808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9I7S2-1", "uniprot_id": "Q9I7S2_DROME", "id": "Q9I7S2-1", "name": "Inosine/uridine-preferring nucleoside hydrolase domain-containing protein", "aln": "------------------------------------------------MD-------------------KKHRLVVYDCDIGTDDAWGLAMLLRAEELTLREGRTCKVLAITTV-HGNTDADNGTLNALRVLHTL-NRRDVPVFRGCYESIVPRTWEYTNCFHGQDGLNDVGNYP-VVDVEQELQPEHAVNAMYRLARANPGQVDFLLCGPLTNFANCINLYGNSFLTNIGRVYIMGGNIFGKGNV--TKSAEFNFMMDPEAAHITLER--LLEPAIILPWEPCIDGEFDTTLDWRLNVLGA----VDHPFIELLTRVERS----MLEPRGFVKWISCDSLLTAAYLFPDAMIAEQRQYY----ATVELSGIHTRGQMVLDHLRGRKVDDIHGKKINVHIIRRLTSGATFRTIIAWTGFLPNADIAQLCA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK81-1", "uniprot_id": "Q9VK81_DROME", "id": "Q9VK81-1", "name": "Inosine/uridine-preferring nucleoside hydrolase domain-containing protein", "aln": "------------------------------------------------MEN---------------DTRKLERLVVFDCDIGTDDAWALALLLRGEQLSLASGRRYKLIAITCV-QGNTDVVNGAQNALKILRLL-ERRDVPVFRGCANPIVTRTWLDISRFHGTDGLNDIGGYPDVSDLQEQLQQEHAVNAMYRLVCQYPKQVDFLLCGPLTNFASCINLYGDDFLDKIGGIFIMGGNIYGRGNI--MKCAEFNFMMDPEAAHTTLER--LKVPAVILPWEPSIDDDFNLSLDWRLDVLGS----VDHPLVELLSRVERS----MLVPRDIKHWINPDAALAAAYIFPKAMIAEQLDYH----ATVELAGVHTRGQMVLDHLRGRRVDAIHGKKSNVRIITHLNR-EPFRTIMSWTGFLPGVDITELCEQEQRNNL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYA1-1", "uniprot_id": "Q9VYA1_DROME", "id": "Q9VYA1-1", "name": "Inosine/uridine-preferring nucleoside hydrolase domain-containing protein", "aln": "------------------------------------------------MADGRIVENGRGGGGEGVAAAPSPRYAILDCDGGSDDAWALLLLLHA-----AKSHGIHLLAITTMGCGNTSRENAARNMRRILDAC-KRTDIPIYLGAVDALIPSLEDEKKYFHGRDGFGDCLTDDCALQLEDIVQAEHAVTAIHDLCRSRPKQITIFAVGPLTNLALGYTMYGPEFGNNFRDLFIMGGNYQGVGNS--SRSAEFNFHSDPEAAHTVLLR--TRCPITILPWEACLPERFNIHINWRLKDFAARAKEAGHPAITMLNQVEAAQWLPMIEQYGIDTWNPCDAIAVAVWLFEDHLIRRHNTWH----ATVDLRGTHTRGQMVLDHLRER-----EKYPENVRIIELVDV-EFFKRICEWIAGLDDGALLRDTQ-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2BES5-1", "uniprot_id": "A0A8M2BES5_DANRE", "id": "A0A8M2BES5-1", "name": "", "aln": "MLSSLRFRYILRKAFLTRKLIHGLARNRSKGSPDGCSRHGEHEDTIKRYRFQESLTNTCSLRHFSNVTEFSMKKLFVDVDCGVDDAQAIMMALAVP--------GVQILGISCV-HGNTSVENVCKNVLRILKVC-KHLEIPVFRGANKPLLGQVVG-TGDFHGKDGLGDAPDPE--APGLDLVQKEGAVSAMIRIVNENPGEVSLVATAPLTNVALAVKLD-PSLPQKLKGLYIMGGNTDSRGNT--TMCGEFNFAADPEAAYIVLNE--FTCPVYIAAWEFTCHSKLPWEFCDGWLAQDTDKARFMKQIFQHSMKNSYSER-IEKELVAGQGFISCDSYAIAAAID-DTIILESLERA----VTVELAGNCCRGMMVVDHLDLL------QKTHKAHILKKVDLERFKELLMNALK-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04179-1", "uniprot_id": "URH1_YEAST", "id": "Q04179-1", "name": "Uridine nucleosidase", "aln": "-------------------------------------------------------------------MTVSKIPIWLDCDPGHDDAIAILLGCFHP--------AFNLLGISTC-FGNAPPENTDYNARSLLTAMGKAQAIPVYKGAQRPWK-REPHYAPDIHGISGLDGTSLLP--KPTFEARTDKTYIEAIEEAILANNGEISFVSTGALTTLATVFRCK-PYLKKSVKYISIMGGGLHGLGNCNPNLSAEFNVWIDPDAANYIFRDPDVKDKCIVVPLNLTHKAIATYKVNEMIYNEKNN-SKLRELFLELFQFFAHTYKDMQGFESGPPIHDPVALMPLLEFYGWDPSSAVGFRYKRMDISCIDDVFNENSGKIIIEKEYPN------DSDVGTIIGLDLNIQYFWDQIFEALNRADKMSTIG----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * *** .: : :::.*: **: * * :* : :*:: *. . :** .*:.. : : : *: :: :. ..**..* : .. : ****. . ** ..***. **:** : : . : . . . : . :: * ::::: . * : : ", "identical_positions": 36, "similar_positions": 62, "identity": "8.24%" }, { "cls_id": "homologset.agr.SGD:S000002810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08477-1", "uniprot_id": "CP4F3_HUMAN", "id": "Q08477-1", "name": "Cytochrome P450 4F3", "aln": "-------------------MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSS--EEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDK--VFYSFLKPWLGDGLLLSAGEKWSRH----RRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSFDS--HCQEKPSE---YIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKA-------KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHP-EYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-DGRVIPKGIICLISVFGTHHNPAVWP-DPEVYDPFRFDPKNIKERS-------PLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHT--EPRRKPELVLRAEGGLWLRVEPLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P78329-1", "uniprot_id": "CP4F2_HUMAN", "id": "P78329-1", "name": "Cytochrome P450 4F2", "aln": "-------------------MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNPT--EEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDK--FFYSFLEPWLGDGLLLSAGDKWSRH----RRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDS--HCQEKPSE---YIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKA-------KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHP-EYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-DGRVIPKGIICLISVFGTHHNPAVWP-DPEVYDPFRFDPENIKERS-------PLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHT--EPRRKPELVLRAEGGLWLRVEPLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HBI6-1", "uniprot_id": "CP4FB_HUMAN", "id": "Q9HBI6-1", "name": "Cytochrome P450 4F11", "aln": "-------------------MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPT--EEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDM--IFYGFLKPWLGDGLLLSGGDKWSRH----RRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFES--NCQEKPSE---YIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKA-------KSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHP-EYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP-DGRVIPKGIVCLINIIGIHYNPTVWP-DPEVYDPFRFDQENIKERS-------PLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHT--EPRRKPELILRAEGGLWLRVEPLGANSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HCS2-1", "uniprot_id": "CP4FC_HUMAN", "id": "Q9HCS2-1", "name": "Cytochrome P450 4F12", "aln": "-------------------MSLLSLPWLGLRPVATSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPT--EEGLKNSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDN--LFIRFLKPWLGEGILLSGGDKWSRH----RRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDS--HCQERPSE---YIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKA-------KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP-EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP-DGRVIPKGITCLIDIIGVHHNPTVWP-DPEVYDPFRFDPENSKGRS-------PLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHT--EPRRKLELIMRAEGGLWLRVEPLNVSLQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98187-1", "uniprot_id": "CP4F8_HUMAN", "id": "P98187-1", "name": "Cytochrome P450 4F8", "aln": "-------------------MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGHLGLVTPT--EEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDI--VFYKTLKPWLGDGLLLSVGDKWRHH----RRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFDS--NCQEKPSE---YITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKA-------KSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP-EYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLP-DSRVIPKGNVCNINIFAIHHNPSVWP-DPEVYDPFRFDPENAQKRS-------PMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHR--EPRRTPEIVLRAEDGLWLRVEPLG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N16-1", "uniprot_id": "CP4F3_MOUSE", "id": "Q99N16-1", "name": "Cytochrome P450 4F3", "aln": "-------------------MSQLSMSWMGLGHTAASPWLLLLLAGASCLLAYILTPIYGVFENSLRLRCFPQPPKRNWILGHLGLIQSS--EEGLLYIQSLVRTFRDACCWWVGPLHPVIRIFHPAFIKPVVLAPALVAPKDT--VFYRFLKPWLGDGLLMSTGDKWSRH----RRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQRLASKGSAYLNMFEHISLMTLDSLQKCVFSFDS--NCQEKPSE---YITAILELSTLVARRHQRLLLHVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRRTLLDQGGVDVLKAKA-------KAKTLDFIDVLLLSKDEHGKALSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHP-EYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLP-DGRVIPKGVISRISIFGTHHNPAVWP-DPEVYDPFRFDADNVKGRS-------PLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLPDDK--EPRRKPELILRAEGGLWLKVEPLSAGAQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NT55-1", "uniprot_id": "CP4FN_HUMAN", "id": "Q6NT55-1", "name": "Ultra-long-chain fatty acid omega-hydroxylase", "aln": "-----------MLPITDRLLHLLGLEKTAFRIYAVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPN--EAGLQDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDD--LFYGFLKPWLGDGLLLSKGDKWSRH----RRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSYNS--NCQEKMSD---YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQQGAEAWLKAK--------QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYP-EYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-DGRIIPKGIICLVSIYGTHHNPTVWP-DSKVYNPYRFDPDNPQQRS-------PLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTR-KVRRKPELILRTENGLWLKVEPLPPRA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V558-1", "uniprot_id": "CP4P1_DROME", "id": "Q9V558-1", "name": "Cytochrome P450 4p1", "aln": "----------------------MIILWLILALSALLYWLHRANK--DYHILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGRD--HAGVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKG----LVYNFLHPFLRTGLLTSTGKKWHAR----RKMLTPTFHFNILNQFQEIFKTESQKFLLQFE---GQDEVTITLHDVIPRFTLNSICETAMGVKLD-EMAEKGDR---YRENFSQIEECFIRRLSNPLLWGDKLFEMFA-AKDFASALDVVHRFSSEIIAKRRDLLKDELDK--SSSTADDDGFVS-KKRFAMLDTLIYAEKDG--LIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNP-DKQELCYQEIQEHIDD-DLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELA-NGLILPKGAQITIHVFDIHRNAKYWD-SPEEFRPERFLPENVQDRH-------TYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTGITLRTQDKIRVKLVRRT-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V559-1", "uniprot_id": "CP4P3_DROME", "id": "Q9V559-1", "name": "Probable cytochrome P450 4p3", "aln": "----------------------MLILWLVGAFIVLIQWIYRLNR--DYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFDLYGKD--HSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKG----TIYDFLHPFLRTGLLTSTGKKWHAR----RKMLSPTFHFNILNQFQEIFITESLKFLEQFK---GNDEAIISLNEVIPRFTLNSICETAMGVKLD-EMAEKGDR---YRENFRQIEECFIRRMSNPLLWSDTLFKMFA-EKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTS-KKRFAMLDTLILAEKDG--LIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYP-EEQEKCYQEIQANIDD-ELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELS-NGLILPKGSQIFVHVFDIHRNPEYWD-SPEEFRPERFLPENSQNRH-------TYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVKLVRRK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V557-1", "uniprot_id": "CP4P2_DROME", "id": "Q9V557-1", "name": "Probable cytochrome P450 4p2", "aln": "--------------------MMICLLWISVAILVVIHWIYKVNK--DYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGKD--TDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKG----VIYNFLHPFLRTGVLTATEKKWHTR----RSMLTRTFHLDILNQFQEIFIAESLKFVSQFQ---GQNEVVVSLKDRISRFTLNSICETAMGIKLD-EMAEKGDR---YRANFHIIDEGLTRRIVNPLYWDDCVYNMFT-GHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLICAEKDG--LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYA-AEQELCYQEIQEHILD-DLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELE-NGLILPKRSQINIHVFDIHRNPKYWE-SPEEFRPERFLPQNCLKRH-------PYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRRNCV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGB3-1", "uniprot_id": "CP133_DROME", "id": "Q9VGB3-1", "name": "Probable cytochrome P450 313a3", "aln": "-----------------------MDTFQLLLAVGVCFWIYFLWSRRRLYMMHFK---------------IPGPMGLPILGIAFEYLITY--KRKMSIRTKYMDIYGSTCLVWVGP-TPFVITRDPKIAEEIFLSPECLNRSS---IFSKPVNSCTGDGLLSLEASKWVDR----RKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGE--KKVRDDIVRWSFRIATQTTVGTDVKKDASFKNDS---VLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQKALAKSNVNKMIGTIVDKKLMT-----KPESGSQP----------EITSVINKAIELHRNG--EMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFP-EHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLS-SGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRH-------PYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQSPGLEFHRRT-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFJ0-1", "uniprot_id": "CA131_DROME", "id": "Q9VFJ0-1", "name": "Probable cytochrome P450 313a1", "aln": "-----------------------MLTINLLLAVGALFWIYFLWSRRRLYFLMLK---------------IPGPIGLPILGSSLENIITY--KRKLSFRTKYLNKYGSTILTWMGP-VPFIVTRDPKVVEDIFSSPDCHNKSQ---HIVNAITSCMGNGLLGKQDPHWLDR----RKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE--IDVVPEMLRWSFKIAAQTTMGSEVKHDEHFKNGS---LVESFESLISHSTLNILMPLVQNRMISKICGYDKLRADNFSRIQKMLDNVVNKKVNP-----LPKTDSDP----------ESNIVINRAMELYRKG--DITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHP-EHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARETKNDVRLS-NGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKH-------PYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVYVDNMTMKLAEYPRLKLQRRG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG40-1", "uniprot_id": "CP134_DROME", "id": "Q9VG40-1", "name": "Probable cytochrome P450 313a4", "aln": "-----------------------MLTWTLWCGLLFLLWIYFLWSRRRFYLLTLK---------------IPGPLGYPILGMA-HWLMRR--EDILNAFGCFLDKHGPTIFSWLGP-IPFMIVSDPQVVQDIFTSPHCVNKG----IIYKAVDDGAGVGLFSLKDPRWSIH----RKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGE--KDLIPLLQSFTLGIATQTTMGSDVKDEESFRSNS---LLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSN-----------DKNLFLNLVTDLMRRG--VFTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFP-EYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLS-NGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKH-------PYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLKSVPLLELQKRT-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PZ56-1", "uniprot_id": "A0A8M1PZ56_DANRE", "id": "A0A8M1PZ56-1", "name": "", "aln": "-------------------------------MDMLHFYEWIDIKS-ILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDP----SKLHLQLSEFAEKYGKIFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRA---ILPLFHDIIGDKGLVASSG-YKWKQ----QRRFALSTLRNFGLGKKNLEPSINLESGFLNEAISNEQGQPFDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTL---LKNINETVHLEGGICAQLYNMLPWLMRLLPGPHKRIIALWGKLIEFVGEKVNEHKVDHDPLNPRDYIDC---------------FLDEMEKHKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYP-EIQAKVQQEIDVIVGG--SRQPSVSDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQI-EKYSIPKGTMVTSNLTSVLFDESEWE-TPHSFNPGHFLDAEGKFRR-------RDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPP-AGVEPS-LDYNLGATHCPQPYKLCAVPH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JTQ9-1", "uniprot_id": "A0A0G2JTQ9_RAT", "id": "A0A0G2JTQ9-1", "name": "unspecific monooxygenase", "aln": "-------------------------MLATVGSLLAKIWSAINFWT-LLLTLLTFLLLADYLKNRRPNNYPPGPWRLPFVGNLFQFDLNI--SHLHLRIQQFVKKYGNLISLDFGNISVVVITGLPLIKEALINNEQNFLKRP---IVPSRYRVFKDNGIFFANV-HKWKE----QRRFALTMLKNFGLGKKSLEQCIQEEAHHLVEVIGEEKGQPFDPHFRINNAVSNIICSITFGERFEYDDSQFQEL---LKLADEVICSEASMTSVLYNVFPLIFKYLPGPHQTVFKNWEKLKSIVANMIDRHRKDWNPDEPRDFVDA---------------FLTEMTKYPDKTTTSFNEENLIATTLDLFFAGTETTSTTLRWALLYITLNP-EVQEKVHSEIDRVIGH--GRLPSTDDQDAMPYTNAVIHEVLRMGNIIPLNVPREVTADSTL-AGFHLPKGKMILTNLTALHRDPKEWA-TPDTFNPEHFLE-NGQFKK-------RDSFLPFSVGKRACPGEKLAKSELFIFFTALMQNFTFKAP-TNEKLS-LKLRKGLSLYPVSYRICAVPR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N004-1", "uniprot_id": "A0A8M1N004_DANRE", "id": "A0A8M1N004-1", "name": "", "aln": "-----------------------------MFGALVKLDLSSVGLT-LLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLR------DPMGFNRLMAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQ--EAFAGRP---CLPVIDWTSNGCGIIMATFNNSWKQ----QRRFALHTLRNFGLGKKSIESRVLEESQYLFAELLKDEGEPVNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYL---LKILNENMMLTGSAIGQIFNLAP-FIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDA---------------YLLEIEKQKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLIQNP-DVQERCHEEIVQVLGY--DRLPCMDDCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKL-HGFDIPQGTMIMTNLAAIFSSKEHWK-HPDTFNPENFLDENGHFSK-------PESYIPFSLGLRACIGESLVRTELFLFATVLLQRIHFSWP-PDAKPLDMDGIVGIVRYPQTFSIICCSRDSKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NWJ8-1", "uniprot_id": "A0A8M1NWJ8_DANRE", "id": "A0A8M1NWJ8-1", "name": "", "aln": "-----------------------------MLAALLKLDLSSVGLS-LFLGLIFLVLFEIFRIHSCKGRFPPGPTPLPFVGSIPHFLN------NPMGFIKSLSQYGEMTTVYPGRKPAIILNTLQLMKEALVQNGSSFSGRP---PVPVFNWVTDGYGIVMATFGHSWRQ----QRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLKAEGKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYL---LEIIKENIIQAGSLVGQVFNLVP-IIKHVPGPHQKIYQNGQAFKSFIRESVKEHRQTLDPDSPRDFIDA---------------YLLEMEKQKSTQDSTFHEDNMVMAVGDLFLAGSDTTATTIRWGLIYLTQNP-DVQERCHEEIVRVLGF--DRLPSMDDRDRLPYTHATVHEFQRCANLVPTGVPHQTTQATKL-RGYDIPQGTQILINLTEILTNKEHWK-HPDTFNPENFLDDKGHFFK-------PEAFLPFSLGPRACLGETLAKAELFLFVTSLLQRIRFSWP-TGEKLPDMNGIFGIVRSPKPFNIICHSRGSKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7FAJ1-1", "uniprot_id": "F7FAJ1_RAT", "id": "F7FAJ1-1", "name": "Vitamin D 25-hydroxylase", "aln": "-----MGVRQGWKARPGLSETNWFPPQPWPMFQLPGVQTCAGALAGAFLLLLLVLVVRQLLRQRRPAGFPPGPPRLPFIGNICSLALSA--DLPHVYMRKQSRVFGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRP---CLPLFMKMTKMGGLLNSRYGRGWID----HRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGRPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHM---IELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSKLIEKAAVNRKPHLPQNFVDA---------------YLDEMDKGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAVLFMALYP-NIQGQVHKEIDLIMGH--DRRPSWEDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVV-RGYSIPKGTTVITNLYSVHFDEKYWK-DPDMFYPERFLDSSGYFTK-------KEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFP-HELVPN-LKPRLGMTLQPQAYLICAERR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K2P4-1", "uniprot_id": "A0A0G2K2P4_RAT", "id": "A0A0G2K2P4-1", "name": "unspecific monooxygenase", "aln": "---------------------------------MVTCEATLLLLLILTLMLMSWGWLAHQARARMQKDLPPGPAPLPLLGNLLQLQSG----HLDRVLMELSSRWGPVFTVWLGPRPAVVLSGYAALRDALVLQADAFSGRG---SMAVFERFTHGNGIVFSNG-PRWRT----LRNFALGALKEFGVGTSTIEERILEETACVLDEFQATMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRL---LDLFSDNFRIMSSRWGETYNMFPSFMDWIPGPHHRIFKNFQELRLFISEQIQWHRQSRQTGEPRDFIDC---------------FLEQMDKEHQDPESHFQDETLVMTTHNLFFGGTETTSTTLRYGLLIMLKYP-EVAAKVQEELDATVGR--TRAPSLADRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNL-RNHFLHKGTFVIPLLVSAHRDPTQFK-DPDHFNPTNFLDDQGEFQN-------NDAFMPFAPGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPADIDLTPQCTGLGNVPPAFQLRLVAR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21595-1", "uniprot_id": "CP56_YEAST", "id": "P21595-1", "name": "Cytochrome P450-DIT2", "aln": "-------------------------------MELLKLLCLILFLTLSYVAFAIIVPPLNFPKN------IPTIPFYVVFLPVIFPIDQT--ELYDLYIRESMEKYG-AVKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVWRNY----RNAVTNGLQH---FDDAPIFKN-AKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVALGFDFG---ALTHEK---NAFHEHLIRIKKQIFHPFFLTFPFLDVLPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAAS--------------------DLIRAHNNEIIDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDP--------KGLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKFNENIME-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A8WGA0-1", "uniprot_id": "C27C1_DANRE", "id": "A8WGA0-1", "name": "Cytochrome P450 27C1", "aln": "MALQSTILHMARKNLLQESCRQLLIQTHGLHKSVASGSLEIAAHSQADLKEESAVSPAEEVQKAARVKSLKEMPGPSTVANLLEFFYRDGFSRIHEIQMEHAKKYGKIFKSRFGPQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYRDLRGRSTGLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQDDSQTVLNINDLFFKYAMEGVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKRLSEIKKQMEKSEEIKGG------------------LLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHP-TIQQQIFEEVDRVLGG---RVPTGEDVPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVG--GYLIPKGTQLALCHYSTSMDEENFP-RPEEFRPDRWIRKDASDRVD------NFGSIPFGYGIRSCIGRRIAELEMHLALTQLLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q8E0-1", "uniprot_id": "A0A8M9Q8E0_DANRE", "id": "A0A8M9Q8E0-1", "name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "aln": "------------------------MARWSLSARLDQSVSSLKHLLQVIVTRSGRAPAIGLQDSTVRPFNEIPGQWRNSLKSVFAFAKMGGLRNIHRIMVHNFNTFGPIYREKVGFYESVNIIKPEDAAILFKAEGHYPKRLTIDAWTAYRDYRNRKYGVLLKDGEDWKSNRIILNKEVISPKVQGNFVPLLDEVGQDFVARVNKKIERSGQNQWTTDLSHELFKFALESVSAVLYGERLGLLLDYIDPDS--QRFIDCITLMFKTTSPMLYLPPGLLRPIRSKIWRNHVEAWDGIFNQADRCIQNIYRQLRKNPEGNGKYTG-------------------VLASLLMLDKLSIEDIKASVTELMAGGVDTTAITLLWTLYELARNP-DLQEEIRAEISAARIAS--KGDMVQMLKMIPLVKGTLKETLRLHPVAVSLQRYITEDIVIQ--KYHIPAGTLVQLGLYAMGRDHQVFP-NPEQYLPSRWVNSQNHYFK----------SLSFGFGPRQCLGRRIAETEMQLFLIHMLENFRIEKQRQ-MEVKSMFELILLPEKPIMLTIKPLNSSR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:. . . : : : :. . :.. . : . *: : : * * : . : . : * .: * * * * * . : . ", "identical_positions": 9, "similar_positions": 31, "identity": "1.56%" }, { "cls_id": "homologset.agr.SGD:S000002812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62487-1", "uniprot_id": "RPB7_HUMAN", "id": "P62487-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62488-1", "uniprot_id": "RPB7_MOUSE", "id": "P62488-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62489-1", "uniprot_id": "RPB7_RAT", "id": "P62489-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZW41-1", "uniprot_id": "RPB7_DANRE", "id": "Q7ZW41-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTVDEDVVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFB5-1", "uniprot_id": "Q9VFB5_DROME", "id": "Q9VFB5-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEQEILLHPRYFGPQLLETVKQKLYSEVEGTCTGKYGFVIAVTTIDQIGS--GVIQPGQGFVVYPVKYKAIVFRPFKGEVLDAVVKQINKVGMFAEIGPLSCFISHHSIPADMQFCPNGNPPCYKSKDEDVVISGEDKIRLKIVGTRVDATGIFAIGTLMDDYLGLVSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34087-1", "uniprot_id": "RPB7_YEAST", "id": "P34087-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSED--VITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .*. :* *** :***.: : :* ** ****:****:*:::.* *:*. * * * * . : ***:*:**:******:*..* . .: *: .::**:. *:::* :* :: * ...***.*:: :: ** ...**:** * : ..*.***:: :**** : ", "identical_positions": 69, "similar_positions": 60, "identity": "39.43%" }, { "cls_id": "homologset.agr.SGD:S000002813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63750-1", "uniprot_id": "RM23_RAT", "id": "Q63750-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVLYPLYQ---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKEPTSPD--------PLEEELPQQRQSSD--------PRCPGIPSWFGL------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35972-1", "uniprot_id": "RM23_MOUSE", "id": "O35972-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVLYPLYQ---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKDPRSPE--------PLEEELPQQRQSSD--------LRCPGIPSWFGL------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16540-1", "uniprot_id": "RM23_HUMAN", "id": "Q16540-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVVYPLYR---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGVAQPEDTVQFRIPMEMTRVDLRNYLEGIYNVPVAAVRTRVQHGSNKRRDHRNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKD-ESPEGSAADDLYSMLEEERQQRQSSD--------PRRGGVPSWFGL------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQS9-1", "uniprot_id": "RM23_DANRE", "id": "Q6IQS9-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MAKRIIYPLYQ---LGNPQ--------------------------------------------------------LRIFRPTFNMTLVRPGKEQPPDTVQFRISMAMTKCDVRNYLEKIYSVPVSAVRTRIQYCSNKKRNHLNQRVKRPDYKVAYVQLAQQQTFQFPD--------IFPEKDKKSKEGSVEEMHEKFMEDE-RQRQKPD--------PRRGGVTEWFGL------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W021-1", "uniprot_id": "RM23_DROME", "id": "Q9W021-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MSTR-WYPIYQ---RGNPQ--------------------------------------------------------LRVFLPNFWMKLIRPTEEQPPNVVTFSVSMEMTKYDVRNYLEKIYKLPVVDVRTRIAMGETKKDQTYGYITKKDDVKLAYVTLPREESFVFPD--------FFSEKAEKQAK-----EEKSLDESKAGFRRFLDR------NKKRPGTPGWFSI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32387-1", "uniprot_id": "RM41_YEAST", "id": "P32387-1", "name": "Large ribosomal subunit protein uL23m", "aln": "MPRLTVGTKNMLYPLQKTLAVGSCKPEQVPIRSLASVVESSSKILDKSGSDREVDINVSEKIYKWTKAGIEQGKEHFKVGGNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLLHGKFNRMNLQTTRFREP--QIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERLNCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDNKRERHAAELQRADKLIALNRYIEDLH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **: : *. : ::: .. : *:** :. . * :. :.: *:*:** ** : . : *:: . .: : :. :: : : :.* :*: :: .. . . : .. * . :: ", "identical_positions": 17, "similar_positions": 54, "identity": "6.42%" }, { "cls_id": "homologset.agr.SGD:S000002815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU02-1", "uniprot_id": "E9PU02_RAT", "id": "E9PU02-1", "name": "", "aln": "-------------------MSVPDYMQCAEDHQTLLVVVQAVGIVSEENFFRIYKRICSVSQLSVRDSQ---RALFIRYRHHYPPENNEWG-------------DFQTHRKVVGLITITDCFSPKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGDVAEQP------------------------RPDVAFYPNYDDCDSVEKR-------------------IEDFIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKD-----------FVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGG----TGGKTGARRLPGNSLPSEAANRHRP---------GALTTNGIN-------------------------------------------------PDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRG-----MEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYS---LSLDPKDFNKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTAKCPGTM---EPITLPDGLT--LPPVPFTKLPIVRCVKLLSLPTSLRPQKVKSLLGQSMSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLP---------AALSLPAESGLYPVTLVGVPQTTGMITVNGYHTTVFGV-FSDCLLDNLPGLKTSG-STVEVIPALPRLQISTSLPRSAHSLQPSAGDEIATNVSVQLFNGETQQLAITLENIGLEPLEQLEVTSKLLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKAKLDFSCQEN------------------------------LLQDLSDDGISVSGFPLSSPFRQVVR---PRVESRPTNPSEGSKTG----DLGHVKTLEAILNFKYSGGPGHVEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVCARNNSELVLHASECQRMAIQVDKFNFESVPES---------PGEKGHFANLKQLEEERQEARGLEISSKLDIRWRIPSLK-RSGEASVEGLLN-QLILEHLQLAPLQWDVLVDGQPCDCEVAAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDVISFVGSSTFYLDTVQPSGQSACLGALLFLYTGDFFLNIRFHEDCKSKELPPSWFCLPSVHVRALEAQA-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0M1-1", "uniprot_id": "TPPC9_MOUSE", "id": "Q3U0M1-1", "name": "Trafficking protein particle complex subunit 9", "aln": "-------------------MSVPDYMQCAEDHQTLLVVVQAVGIVSEENFFRIYKRICSVSQLSVRDTQ---RALFIRYRHHYPPENNEWG-------------DFQTHRKVVGLITITDCFSPKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGDVAEQP------------------------RPDVAFYPNYDDCDSVEKR-------------------IEDFIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKD-----------FVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGG----TGGKTGARRLQGSSLPSEAANRHRPGAQEVLIDPGALTTNGIN-------------------------------------------------PDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRG-----MEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYS---LSLDPKDFSKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTAKCPGTM---EPITLPDGLT--LPPVPFTKLPIVRCVKLLSLPTSLRPHKVKSLLGQSMSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLP---------AALSLPAESGLYPVTLVGVPQTTGMITVNGYHTTVFGV-FSDCLLDNLPGLKTGG-STVEVIPALPRLQISTSLPRSARSLQPSAGDEIATNVSVQLYNGETQQLAVTLENIGLEPLEQLEVTSKLLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKAKLDFSCQEN------------------------------LLQDLSDDGISVSGFPLSSPFRQVVR---PRVESRPTNPSEGSKTG----DLGHVKTLEAVLNFKYSGGPGHVEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVCARNNSELVLHASECQRMAIQVDKFNFESVPES---------PGEKGHFANLKQLEEERQEARGLEISSKLDIRWRIPSLK-RSGEASVEGLLN-QLILEHLQLAPLQWDVLVDGQPCDCEVAAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDVISFVGSSTFYLDTVQPSGQSTCLGALLFLYTGDFFLNIRFHEDCKSKELPPSWVCLPSVHVRALGAQA-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q05-1", "uniprot_id": "TPPC9_HUMAN", "id": "Q96Q05-1", "name": "Trafficking protein particle complex subunit 9", "aln": "-------------------MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRICSVSQISVRDSQ---RVLYIRYRHHYPPENNEWG-------------DFQTHRKVVGLITITDCFSAKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQP------------------------RTDVAFYPNYEDCQTVEKR-------------------IEDFIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKD-----------FVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGG----TGGKSGARRFQGSTLPAEAANRHRPGAQEVLIDPGALTTNGIN-------------------------------------------------PDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACIKAVRVLAIQKRS-----MEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYS---LSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENYTSKCPGTM---EPIALPGGLT--LPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLP---------AALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGV-FSDCLLDNLPGIKTSG-STVEVIPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQEN------------------------------LLQDLSDDGISVSGFPLSSPFRQVVR---PRVEGKPVNPPESNKAG----DYSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPES---------PGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPSLK-RSGEASVEGLLN-QLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIL0-1", "uniprot_id": "BRUN_DROME", "id": "Q9VIL0-1", "name": "Protein brunelleschi", "aln": "MRAAVGLMLSHGAGGMEPALSRPDYEQSALHHSCLLVLLRGVGPSRARVLQRAFEKVRRVNHIRVNDSSGHPRSIWIRFVHDHPVEHNDWG-------------DFQTHRRLLGLVTIGKFDSQIELNELCRQHESLKVRYGSTLYESRAIFFGPDEQPLETIGEVLGPPAAGGRRLQDEFTTPSNFKAQAFFYREQDSCADLESR-------------------IGDFASALFWVLESRRLERSREK-ADKVSLLLAPFEKRD-----------FVGLDMESRNNRKRCVGRVMKNLADLSLQAGLVDDALSLYHNANETLRSVGDSLWVGATEEGLCAASAMLLYPQMRETETLHRNSSLQEAGTSPLKNTPEKWRASDATKKISASDATANNVDSNQPQQRVTSNSSSCSSVSSLVTTATNSSASDTPTTSSSSTSTISAAPIPGHQRNGDLPGNILKAEEISNYYRKAIINYSKYRHAATIETEAALKASRICIEQNRP-----LDVAMFLQNILYINLS-MSEAERVKRFEVITDLYQQIGYQRKAAFFQRLAALKHVQQGSQAPDWNQSYRLMLGSFTGYR---LCLDPLEVIEN-AAGWPALQIDLVQTLITAARRLGHSALATRHMTFLLQTQWDNMSPTEQSEMAVQLQNLSAQCEGSP---VPLVLENGTV--IPPANLTDLPYCIDLQVKDLPAHLRPQRIKVAKADSGPFLFTPIHFNSVDRRDKKKDKNKIAFQWVQNDLSEVTVRLRNPLPFELPVTDMRLLTNGVVFESLP---------QTLVLQPHVPTY-VALHGTPIETGQLDLQGYSTHTLGV-KSNCRLKHMRGRSFPPNYVVDVIPALPRISVKTSLPQTATFSNMNSADIVVTSASLTLYNGESSSCTITITNESATLPLEHLEFSINSNVEQELQQKIFRIDEEAIKAHLPVPPQGTIEIIVDVFAEADFVCPQPPASLHSAAAPGDYGASSLTHYSSVSTSGHASLPSRVGSPHHRRNEPQNSSFRSTISGGPPSLAALTLHPGGGGGVGPSSLGSQYNQHIEAQVRFKYSGGDALTAGYCRQCAVSFNLELLPSVQITSWDVLPAEVASQFYLVLDISNLTAQEMSLNYTDTKNILIEAKESCRVPIPVDRCSLEKVVAARAAEVAENLERELCFRTQLLSFNDALSKLCSIHIAERVKIKWLLTGTD-IQGIASLRGIVLSQSMVDLTAVSPLEWAISFQDTLVQPHNEIVCTVGQRSLLSIQLANQSLQPLRNLVLSIKFYQDYLNGMENYNLETRVAISGPNRIAIPLLEKQEQKEHTCSVIFFTPGRFKASIECTSNPQKQSEQPSSLLTRSCPAEAESVGQSVMFSSSYDEQQAHVWKFIPPIEVTVVEQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04183-1", "uniprot_id": "TR120_YEAST", "id": "Q04183-1", "name": "Trafficking protein particle complex II-specific subunit 120", "aln": "-------------------MNILKHFPSYVGPSKIRTLVIPIGHWTRKEFNNAVQKLSEFNEIHLSDVTPIDSPIFTPQGFPHGKLFFDFLTIDHDDALELFLYDFEPFRKTFVIIGLVNDYSDPLTNLNFMKEKYPTLISPNLVYASSTPTKELEQTIDTMENVFASSPDMQKNIETIMCDIARNFLTALNSYYSSYKHVTLRSPGAIGGNAVLKTTLIRQNSYTSSSSSTPMSAVQSSVSSSSKAGSVTTASKRLSSFEMTTNSLKRSASLKLATTLSTSENRSQQKSLGRQMKILGNFQLLAGRYVDALNSFVDAITTLYKVRDYLWLGSALDGISICFLLLSYLGLS--YQIPQIVSLICPVEKLNFESSSTGISPVDSNSKATASTTASSTPRNSISIAAMQSPRNSIMSLSAPALNIDVENINLPLLIKCISDKVLYYYDLSLMHNSEYAPQVVYCEFLLKTLTFMTSCYKSSEFSKDVLDNIVKNQHRALSDIPNSPMFPRFEVYFYSNKLFELQLKEMQVEAQIKIYSTMAEVYRLLGYKRKQLFVLRLLMVALLATPN-KIAWHPDYRTLIDTIIELLNINESEAKINVDDPSQSTWLILQKKILQLCIKVSRKINDFEYVAKFSSILITKYTHLLNQSEQDALFKEYIQPSITNESITSYWDPFILREVVINRILDSDPTSNEIPLESDVSSLESLENRQKTQDINPQEVFNPFKRVQPTSFVSNNS---TKVPILVFLVGDKAEFTCRVQNPFKFDFTINDIQLDEEISEFCEIDRKAVSYSGPYNVKAESIRSITLPLIIKKPTYKKIYEISCLKISILKLPLQKFDIINDSRRSNPVEEEAEYSKCIYGKLKIKILPEQPQLELLSTSKMTRN--SWMMLDGTKTDFHITVRNKSLSCAINHIKIIPMNNIEQMLKPDYWKKMPPDDLYIMEKQLDWLSKSCVRIIKLPTVIKPNE-------------------------TITFDLELDNTAVPFNFTGFDLLIEYGMSATDESCIYLKKLSIPYEVTLRR---TIEVPSMDIIPLNELFSSQVENVDWIEYVMSKIRAESNLHSRDFILLLLDFRNSWIDGIKLNVQFEDFTSNEYHVEASHTSRIIVPIKKIDYKKYNFENTPIPRIYPGR--------QFIQSGLNEEQTIEMRQKFWCREHIISKLKCNWKLTTDQSVTGSVDFNKFIEKFDHKMVYTIYPGRLFYGVQLLLDEPKVKVGEIINLKIITEPTSTCRRKQNSTVNFLDIVIFDSKTSKILPR-SNRRILYNGSLTKPISTTKVSEIN---LEIIPIEKGRYEFSVCISKSNNQD----GIIQFDSENVILSVI-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: . . : .:: :* . : . ::: ...: : * :: . : :: **:..*: . :: : . * : . . . :* * : . * . . :.. . .: : .::* . : . . .** . *. .... :::. ** * :.:: * ** *:* : : * .* * **:*:: :*:. . : * : : . ::.. . . *:.. . : . : : * : . *.. . : : : : * . ::. : :: . ::* :. ::: :. ::::*. :*::** *. *: : : *. *: :: :: . :. * :* ::: : .:*::.. .:. ::*: . . :. *:. : . : : . *: * : *. .: .* : . :: : :. : . . .: : :: .* .*. : **: *:: : :: * . * .: : . : * . :. : : .. : : . .: .: . **. . .:.. . * : :* . . :.: * . : . :: * . : : : . : . . : * : . .: * : . :: . : : * ::. : * :* : .. ::: : .:. : . . : :: .* .:: * :. . * .... :: : * . .: : . :. . : : : * : ::. . : . : *. : : . . :: : * : : .. .. . . * . ", "identical_positions": 78, "similar_positions": 341, "identity": "5.61%" }, { "cls_id": "homologset.agr.SGD:S000002816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22102-1", "uniprot_id": "PUR2_HUMAN", "id": "P22102-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREP--NSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKN-------------RVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWN-GKMLNIHPSLLPSFKGS-NAHEQALETG-----VTVTGCTVHFVAEDVDAGQIILQEAVPVKRGD-TVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04161-1", "uniprot_id": "PUR3_YEAST", "id": "P04161-1", "name": "Phosphoribosylglycinamide formyltransferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARIVVLISGSGSNLQALIDAQKQGQLGEDAHIVSVISSSKKAYGLTRAADNNIPTKVCSLYPYTKGIAKEDKAARAKARSQFENDLAKLVLEEKPDVIICAGWLLILGSTFLSQLQSVPILNLHPALPGCFDGTTHAIEMAWRKCQDENKPLTAGCMVHYVIEEVDKGEPLVVKKLEIIPGEETLEQYEQRVHDAEHIAIVEATYKVLQQLHK-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.*****:*********: :: ...*:* ***.. . ** :* .***:* . *.: * :*:. : :: * . *:: **:: **...*:.: : :**:**:* .*.*: :* * * .. .:** **:* *:** *: :: : : : *: *: .:**: *** : * * . : ", "identical_positions": 66, "similar_positions": 64, "identity": "6.39%" }, { "cls_id": "homologset.agr.SGD:S000002817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70260-1", "uniprot_id": "PIAS3_RAT", "id": "O70260-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPS--PLA------SIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYS----PVQEGNQSENK-KRVEVIDLTIE------------------------------------------------SSSDEED-LPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYSPSVITS-----LDEQDTLG--HFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSSLREGHGGPLPSGP-----SLTGCRSDVISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54714-1", "uniprot_id": "PIAS3_MOUSE", "id": "O54714-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYS----AVQEGIQPESK-KRVEVIDLTIE------------------------------------------------SSSDEED-LPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS-----LDEQDTLG--HFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSSLREGHGGPLPSGP-----SLTGCRSDVISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X2-1", "uniprot_id": "PIAS3_HUMAN", "id": "Q9Y6X2-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLAPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYS----PVQGGDPSENK-KKVEVIDLTIE------------------------------------------------SSSDEED-LPPTKKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS-----LDEQDALG--HFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPSGP-----SLTGCRSDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88907-1", "uniprot_id": "PIAS1_MOUSE", "id": "O88907-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPPTLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRSKKEVQEVTASYN-GVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTID------------------------------------------------SSSDEEEEEPPAKRTCPSLSPTSPLS--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NSLRESHGHGVASRSSADTASIFGIIPDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIY4-1", "uniprot_id": "A0A8I6AIY4_RAT", "id": "A0A8I6AIY4-1", "name": "", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRSKKEVQEVTASYN-GVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTID------------------------------------------------SSSDEEEEEPPAKRTCPSLSPTSPLS--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NSLRESHGHGVASRSSADTASIFGIIPDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75925-1", "uniprot_id": "PIAS1_HUMAN", "id": "O75925-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGTWAPMRSKKEVQEVSASYN-GVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTID------------------------------------------------SSSDEEEEEPSAKRTCPSLSPTSPLN--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPTTNGSSSGSNSSLVSS-NSLRESHSHTVTNRSSTDTASIFGIIPDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C5D8-1", "uniprot_id": "PIAS2_MOUSE", "id": "Q8C5D8-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLCDLSTIKSSVFS---LDGSSSP-VEPDL--PVAGIHSLPSTSITPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQPCTKVESSSVFSKPCSVTVASDASKK--KIDVIDLTIE------------------------------------------------SSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGLDFLSLIPVDP------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSP-HESSTHVSSSSSRSETG--VITSSG--------RNIPDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75928-1", "uniprot_id": "PIAS2_HUMAN", "id": "O75928-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGGSSP-VEPDL--AVAGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKK--KVDVIDLTIE------------------------------------------------SSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDP------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSS-HESSTHVSSSSSRSETG--VITSSG--------SNIPDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZ28-1", "uniprot_id": "PIAS2_RAT", "id": "Q6AZ28-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCTPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGSSSP-VEPDL--AVAGIHSLPSTSIAPHSPSSPVASVLLQDTKPTFEMQQPSPPIPPVHPDVQLKTLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQPCTKVESSSVFSKPCSVTVASDASKK--KIDVIDLTIE------------------------------------------------SSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGEQRRNDINNEV------------------------------QLG-------------TSSDTVQQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCP8-1", "uniprot_id": "A0A8M2BCP8_DANRE", "id": "A0A8M2BCP8-1", "name": "", "aln": "--------------------------------------MADIEELRNMVSSFRVSELQVLLGFAGRNKSGRKHELLLRALHLLRSGCSSAVQIKIKELYRRRYPRTFEGLQDLAALKSSIKSFIHLDSGATA-VSSDL--TLP-----TDHSDVLQQRRESCDSPVFHESKPMMNMQQPTTLMAPVHPDVQMKSLPFYDVLDVLIKPSSLGAHAVQRFHNEKYFIFALTPQQVREVCISRDFLPGGRRDYMVQIQLRFCLAETSCPQEDNYPNGLCIKVNGKLFPLPGFAPPPKNGVEQKRPGRPLNITSLVRLSSAVPNQIVVTWAPEIGKTYSMSVYLVRQLTSPLLLQRLRMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTVPCRAVTCSHLQCFDAALYLQMNEKKPTWICPVCDKKATYESLIIDGLFMEILNDC---TDVDEIQFQEDGTWCPMRPKKETLKLSSPCISKIDCSVPVRQSAVVSVPETSSTK--KADVIDLTLE------------------------------------------------SSSDDEEDDPPLKKRCIYMSKAEEMH--SKGVLTY--QPS-TVRVPNVQSLDTSYLTSS-IADYSVPFHHSSLSTIPTDMQSLDLFSLIQGDPQQ----------------------------HFRGPIFLDSLSSSLQSATTSASLVSSSAQYETATHSSSSSHETG--VITGGS--------SGLSDIISLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JM05-1", "uniprot_id": "PIAS4_MOUSE", "id": "Q9JM05-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKTLKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EGADEIEFLAEGSWRPIRAEKEP--------------------------SCSPQG----PILVLGTS------------------------------------------------DAN--------------GLAPASSTPGIGSGLSGPGSAGSGAGAAGSLE----------------------------NGKTGADVVDLTLDSS-------------------------------------------SSSEDEDEDEDDDEDEDE--GPRPKR-RCPFQKGLVPAC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFF9-1", "uniprot_id": "B5DFF9_RAT", "id": "B5DFF9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKALKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EDADEIEFLAEGSWRPIRAEKEP--------------------------SCSPQG----PILVLGTS------------------------------------------------DAN--------------GLAPASSTPGMGSGLSGPGGAGGGAGAAGGLE----------------------------NGKTGADVVDLTLDSS-------------------------------------------SSSEDEDEDEDDDEDDDE--GPRPKR-RCPFQKGLVPAC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N2W9-1", "uniprot_id": "PIAS4_HUMAN", "id": "Q8N2W9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPAPQPHRP--------LDP--LTMHSTYDRAG----------AVPRTPLAGPNIDYPVLYGKYLNGLGR--LPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQ-ESPCIFALTPRQVELIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSEC---EDADEIEYLVDGSWCPIRAEKER--------------------------SCSPQG----AILVLGPS------------------------------------------------DAN--------------GLLPAPSVN--GSGALG---STGGGGPVGSME----------------------------NGKPGADVVDLTLDSS-------------------------------------------SSSEDEEEEEEEEEDEDEE-GPRPKR-RCPFQKGLVPAC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4C4-1", "uniprot_id": "PIS4A_DANRE", "id": "F1R4C4-1", "name": "E3 SUMO-protein ligase PIAS4-A", "aln": "-------------------------------------MAAELVEAMNMVKSFRVSDLQTLLASMGRSKSGLKQDLVGRALRLVQTEYSPELLKNVRQLYETRFPKASAWLAARRPET--------VAVNYPALNS-----------------SPRGTGQG---------TDYLNGIP---KPAPPPAAEVKLVPLPFYHNLETLLPPTELVAQNSEKLQ-ESQCVFDLTPNQVDQIRNSSELRPGMKS---VQVVLRICYTDSIGVQEDQYPPNIAVKVNQSYCHVPGYYPSNKPGVEPRRPCRPVNITPWLHLSTVT-NRVTITWG-NFGKRYSVAVYLVRVFTSGELFNQLKHCSVENPDRCRERIQDKLRFDPESEIATTGLRVSLICPLVKMRLGVPCRVLTCAHLQCFDAVFFLQMNEKKPTWTCPVCDKPAPFELLTIDGLLSEILKETP--EDVEEIEYLTDGSWRPIRDDKEKERE--------------------RENSRTPDY----PVVDICVP------------------------------------------------EAN--------------GHSPAHSGTN-QTGKSG---SGGASAGTGSTS----------------------------GGSGGGTVVDLTLDDS-------------------------------------------SEEEGGGGAEDSEETDDSQDSPAPKRGRYDYDKDLVTAY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTN-LELLAPKVQEVYAQSVQEQNATLQYIDPTR------MYSHIQLPPTVQPNP----------VGLVGSGQGVQVPGGQMNVVGGAPFLHTHS-INSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQ-EVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVEVISDDIELISDDAKPVKR-DLSPAQDEQPT------------------------------------------------STSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSESP-----------------EQQASRQSPEKQTVSEQQ-----------------------------------------LQQQQHEQPATAAVHASLLESLAAAVADQKHFQLLDLAAVAAAAAATASSGQSQNAGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "---------------MINLEDYWEDETPGPDREPTNELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNEPLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVTGGRGMCSAKFKLSKADYNLLSNPNS------KHRLYLFSGMINPLGSRGNEPIQFPFPNELRCNNVQIKDNIRGFKS---------KPGTAKPADLTPHLKPYTQQNNVELIYAFTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQNCQ--KNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNKHDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :: ::* :*: : . * * * ::: : . . : : .*:. : : . : : : . : .. :. : :* : : : . . :* . *.. . : : * : *:*. ::. *:::: : ::..* * : ::** :** **: :: *.: .* ***.*** ::: : : *** ****: : * :. . .:* . ::: :*.* . .: . . . . ", "identical_positions": 41, "similar_positions": 97, "identity": "4.38%" }, { "cls_id": "homologset.agr.SGD:S000002818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVM4-1", "uniprot_id": "ICMT_RAT", "id": "Q9WVM4-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MAGCAARVPPGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLS-FSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAA------GLLMVIFGECLRKVAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQK7-1", "uniprot_id": "ICMT_MOUSE", "id": "Q9EQK7-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MA-AARRGSAGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLS-FSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAT------GLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60725-1", "uniprot_id": "ICMT_HUMAN", "id": "O60725-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MAGCAARAPPGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLS-FSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVT------GLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VU37-1", "uniprot_id": "Q9VU37_DROME", "id": "Q9VU37-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MCAKSRVASPGAGGTSLCSEGRISLYCFLITAALVLIPSVPQN-LYGVVPQVWGAVLWGPFLYYALINMIIRFVLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSLDSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVA------GVVLCLLGEMVRKAAIITAGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFHDRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFIRGYLVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32584-1", "uniprot_id": "STE14_YEAST", "id": "P32584-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "-----------------------------------------------------------MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLG--IFVGLFPQIRFKNFNLFIIALSLFHFLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKLCTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFWWAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * ::::: : :**: :. :: *. :.:*. : :****: *: : * ** .: :**:**:. * * : :* :* *::* : .: * :: ::*: *. *: *** .*.*:*:.:* . * *:.:*:*:: *****:*:*:*:****::* **:. : :. * ** ** ** *:.** :*: *:::* .*:*** ", "identical_positions": 70, "similar_positions": 78, "identity": "22.8%" }, { "cls_id": "homologset.agr.SGD:S000002819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZP9-1", "uniprot_id": "DERL2_HUMAN", "id": "Q9GZP9-1", "name": "Derlin-2", "aln": "-----------------MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGP---VGFNFLFNMIFLYRYCRMLEEGSFRG---------RTADFVFMFLFGGFLMTLFGLFVS----LVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLG-NSIIVDLLGIAVGHIYFFLEDVFPNQPGGIR--------------ILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWG-EGQRLGG-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BNI4-1", "uniprot_id": "DERL2_MOUSE", "id": "Q8BNI4-1", "name": "Derlin-2", "aln": "-----------------MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGP---VGFNFLFNMIFLYRYCRMLEEGSFRG---------RTADFVFMFLFGGFLMTLFGLFVS----LVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLG-NSIIVDLLGIAVGHIYFFLEDIFPNQPGGIR--------------ILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWG-EGQRLGG-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AMH0-1", "uniprot_id": "A0A8I6AMH0_RAT", "id": "A0A8I6AMH0-1", "name": "Derlin", "aln": "-----------------MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGP---VGFNFLFNMIFLYRYCRMLEEGSFRG---------RTADFVFMFLFGGFLMTLFGLFVS----LVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLG-NSIIVDLLGIAVGHIYFFLEDIFPNQPGGIR--------------ILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWG-WDKTDHD-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8K3-1", "uniprot_id": "DERL3_MOUSE", "id": "Q9D8K3-1", "name": "Derlin-3", "aln": "-----------------MAGQRLAAGFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLITTFLFFGP---LGFGFFFNMLFVFRYCRMLEEGSFRG---------RKADFVFMFLFGGVLMTLLGFLGS----LFFLGQALMAMLVYVWSRRSPHVRVNFFGLLNFQAPFLPWALMGFSLLLG-NSVVTDLLGILVGHIYYFLEDVFPNQPGGKR--------------LLLTPSVLKLLLDDPQEDPDYLPLPEEQPEL-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8X2-1", "uniprot_id": "G3V8X2_RAT", "id": "G3V8X2-1", "name": "Derlin", "aln": "-----------------MAGQRLAADFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLITTFLFFGP---LGFGFFFNMLFVFRYCRMLEEGSFRG---------RKADFVFMFLFGGVLMTLLGFLGS----MFFLGQALMAMLVYVWSRRSPHVRVNFFGLLNFQAPFLPWALMGFSLLLG-NSVITDLLGIIVGHIYYFLEDVFPNQPGGKR--------------LLLTPSFLKLLLDDPQEDPNYLPLPEEHPEA-----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96Q80-1", "uniprot_id": "DERL3_HUMAN", "id": "Q96Q80-1", "name": "Derlin-3", "aln": "-----------------MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFFGP---LGFSFFFNMLFVFRYCRMLEEGSFRG---------RTADFVFMFLFGGVLMTLLGLLGS----LFFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLG-NSILVDLLGIAVGHIYYFLEDVFPNQPGGKR--------------LLQTPGFLKLLLDAPAEDPNYLPLPEEQPGPHLPP-PQQ---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEU2-1", "uniprot_id": "Q9VEU2_DROME", "id": "Q9VEU2-1", "name": "Derlin", "aln": "-------------------MNALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTLIVRKFQIWRLATTFLYFGT---IGISFFFNMVFTYRYCRMLEDGSFRG---------RSSDFVMMFIFGGVLMTFFGIFVN----LLFLGQAFTLMLVYVWSRRNPLVPMNFFGVLNFQAPYLPWVLLCCSMILG-NTVWVDVIGMGVGHIYYVLEDVYPTLSNGYR--------------LIKTPYFLKRLFNEHIER-NFQAAAEDRPGGFPWGGEGQPLLPEEIA----------------ADGQDEEPANRAAPVAAAPQ-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99J56-1", "uniprot_id": "DERL1_MOUSE", "id": "Q99J56-1", "name": "Derlin-1", "aln": "-------------------MSDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVGPGTGFLYLVNLYFLYQYSTRLEAGAFDG---------RPADYLFMLLFNWICIVITGLAMD----MQLLMIPLIMSVLYVWAQLNRDLIVSFWFGTRFKACYLPWVILGFNYIIG-GSVINELIGNLVGHLYFFLMFRYPMDLGGRN--------------FLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGG----------------------------RHNWGQGFRLGDQ---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUN8-1", "uniprot_id": "DERL1_HUMAN", "id": "Q9BUN8-1", "name": "Derlin-1", "aln": "-------------------MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDG---------RPADYLFMLLFNWICIVITGLAMD----MQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIG-GSVINELIGNLVGHLYFFLMFRYPMDLGGRN--------------FLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGG----------------------------RHNWGQGFRLGDQ---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LU34-1", "uniprot_id": "A0ABK0LU34_RAT", "id": "A0ABK0LU34-1", "name": "Derlin", "aln": "-------------------MSDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVGPGTGFLYLVNLYFLYQYSTRLEAGAFDG---------RPADYLFMLLFNWICIVITGLAMD----MQLLMIPLIMSVLYVWAQLNRDLIVSFWFGTRFKACYLPWVILGFNYIIG-GSVINELIGNLVGHLYFFLMFRYPMDLGGRN--------------FLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGLSLRHLRTWERKTALPERHGPHRTQSSFLRTTWSSKWMLWEVHVVVVIQASCKPLSSHLLRGPETTSQQDACRSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VQ57-1", "uniprot_id": "DERL1_DROME", "id": "Q9VQ57-1", "name": "Derlin-1", "aln": "--------------------MDAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTSLFVFPISSNTAFHFLINCFFIVQYSSKLEKDQYSR---------SPADYLYLLIVSAVLANIGGMIFN----VYFLMDTLVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFH-FSLA-SLVGIFVGHVYYFFKFQYSQDLGGTP--------------LLETPQFLKRLVPDVSGGFGGFGLPPES--RAPPRQATES------------------------------PWGRGMTLGRN---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12743-1", "uniprot_id": "DFM1_YEAST", "id": "Q12743-1", "name": "DER1-like family member protein 1", "aln": "MAGPRNVRTLHGNGGRNNDVMGPKEFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFIYVWNLTFKKVQIWRLLTSCVMLSS---RAMPALMELYSIYDRSSQLERGHFGPGLSNRRGPMVTVDYAYYLCFCILAITTATTIIYGSYYPVVLTSGFISCITYTWSIDNANVQIMFYGLIPVWGKYFPLIQLFISFVFNEGDFVISLIGFTTGYLYTCLDTHTLGPIWGMISRKADPTYGISPNGKFSTPWWFTSLYARITGAHNETATFNNNFANVPSSQRETRTFSGRGQRLGTAPATLSQTSGTDSGRASGSQLRSGPSNLNQFQGRGQRVGQTNSPSDSQ---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* .:* : : . :: :: : . :.*:** * . : .: :.: . ** . : *: : . . .* : : * *. . : : *: . . ::* . :: . .::* .*::* : * : ** : . ", "identical_positions": 20, "similar_positions": 57, "identity": "5.57%" }, { "cls_id": "homologset.agr.SGD:S000002820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5D1Z3-1", "uniprot_id": "NOL12_RAT", "id": "Q5D1Z3-1", "name": "Nucleolar protein 12", "aln": "---MGRN----KKKK-RDGDDRRP-RLILNFDEEKRREYLTGFHKRKVERKKAAIEEIKQ----RLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPN--HTVTVTTVSDLDLSGARLLGLPLPEQGDQDGSQEEEVSSMEKPTKALPKKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRR------AQDSTKKPPS----------ATRTSKTQRRRRMTGKARHNGE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG17-1", "uniprot_id": "NOL12_MOUSE", "id": "Q8BG17-1", "name": "Nucleolar protein 12", "aln": "---MGRN----KKKKKRDGDDRRP-RLVLNFDEEKRREYLTGFHKRKVERKKAAIEEIKQ----RLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPN--HTVTVTTISDLDLSGARLLGLPLPEQGDQDGSQEEEMSSLEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRR------AQDSTKKPPS----------ATRTSKTQRRRRMTGKARHNGE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGY1-1", "uniprot_id": "NOL12_HUMAN", "id": "Q9UGY1-1", "name": "Nucleolar protein 12", "aln": "---MGRN----KKKK-RDGDDRRP-RLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ----RLKEEQRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPN--HTVTVTTISDLDLSGARLLGLTPPEGGAGDRS-EEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRR------AQDS-KKPPR----------APRTSKAQRRR-LTGKARHSGE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWE7-1", "uniprot_id": "NOL12_DANRE", "id": "Q7ZWE7-1", "name": "Nucleolar protein 12", "aln": "---MGKSDRLQQGSKGKGGGKRKHGKCVLMFDDKDRQDFLTGFHKRKLERRRAALEEMKS----KLKEEQKRLREERHKEYLKMLQERRQALDEADELEEAITATTECVQYDHPN--HTVTVTTISDLDLSADRLL-----EPAQRDGGDGEER---ER-TEALPKQAGNPLLSKKIQSLTASLNSLVKQKKRRKQKRRQEAKQRSHQSDRKSSSSAFVHNNKQKQGKSTKRQRRR-QTGRNERSQD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04031-1", "uniprot_id": "RRP17_YEAST", "id": "Q04031-1", "name": "Ribosomal RNA-processing protein 17", "aln": "MAVHTNRQILTRGKNYATKQSKKFGTDEVTFDKDSRLDYLTGFHKRKLQRQKKAQEFIKEQERLRKIEERQKIRQERKEVMEEQLKTFKESLNLEAEIEDAKNDKTEDLQVESDESWHGFDSDKDDGDNDNNESSVKPILKKGAITEIYDDSTTVELETLEPNDNFEYLAQLNNVKLEKAEKVLKQSINRATKYAKFLG------VDEKQKKKPR--------VKKFRYLTKNERRINQRKANDNKRRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: .:: : **...* ::********::*:: * * :*. : :*::::*:**:: : * .::*: *:: . .** :* : : * . . .. : . : : . : . * : * . ::.. *: .: : : .:. :* . : . :.** : . . ", "identical_positions": 32, "similar_positions": 74, "identity": "12.85%" }, { "cls_id": "homologset.agr.SGD:S000002824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PK0-1", "uniprot_id": "SYF1_RAT", "id": "Q99PK0-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARVPRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYDR------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCD2-1", "uniprot_id": "SYF1_MOUSE", "id": "Q9DCD2-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARVPRSERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYDR------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCS7-1", "uniprot_id": "SYF1_HUMAN", "id": "Q9HCS7-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIAR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYER------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9G2-1", "uniprot_id": "SYF1_DROME", "id": "A1Z9G2-1", "name": "Pre-mRNA-splicing factor syf1 homolog", "aln": "----MVTKTIKSLNLEINFEVEDVPYEEEILRNAYSVKHWLRYIDHK--AKAPNNGVNMVYERALKELPGSYKIWHNYLRTRRKQVRGKIPTDPMYEEVNSAFERALVFMHKMPRIWMDYGAFMTSQCKITRTRHVFDRALRALPITQHGRIWPLYLQFVRRFEMPETALRVYR-----------------------------------------------RYLKLFPED-TEEYVDYLQEADRLDEAAQQLAHIVDNEHFVSKHGKSNHQLWNELCDLISKNPHKVHSLNVDAIIRGGLRRYTDQLGHLWNSLADYYVRSGLFDRARDIYEEAIQTVTTVRDFTQVFDEYAQFEELS---LNRRMEQVAANEAATEEDDIDVELRLSRFEYLMERRLLLLNSVLLRQNPHNVHEWHKRVTLYEDKPAEIISTYTEAVQTVQPK--QAVGKLHTLWVEFAKFYEANGQVEDARVVFERGTEVEYVKVEDLAAVWCEWAEMELRQQQFEAALKLMQRATAMPKRKIAYYDDTE------TVQARLHRSLKVWSMYADLEESFG---------TFKTCKAVYERIIDLKICTPQIIINYGMFLEEHNYFEEAYRAYEKGISLFKWPNVYDIWNSYLTKFLER-YGGTKLERARDLFEQCLDQCPP--EHAKYFYLLYAKLEEEHG-LARHAMSVYDR------ATSAVKEDEMFDMYNIFIKKAAEIYGLPRTREIYEKAIESLPEQNMRHMCVKFAELETKLGEVDRARAIYAHCSQVCDPRITADFWQTWKEFEVRHGNEDTMREMLRIKRSVQATYNTQVNMMAAQFLSTN---NGAAADAGAG-AGPDAMRLLEEKARQAAAESKQKPIEKAASNIMFVRGETQGGAKDKKDTVVNPDEIDIGDSDEDDEEEDDDEENEMTNENQASAAVTKTDEEGLVMKKLRFEQKAIPAKVFGSLKPSNQGDSDGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04048-1", "uniprot_id": "SYF1_YEAST", "id": "Q04048-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "MSAYIAMKGVITNVDENIRNDEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWES--TKEVVETSRIFWLFQRCLK---SCVRDCDRICLSYLELAIEQYDLAMIRHALASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTKGGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLPQDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKYYISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQKDWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKS-AAEKCNVYSEAILKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWADRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYLEAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTIPLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVFEERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQECIQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHGDKETYKDMLKMKKVLESN-------------------------------------MLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTS----SYSINPDEIELDI-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : **:.:* ** :. .: * ***:. .. :. :*** . : . .:* *:: . .: *. : .: . : ::. *: :.* : .* :: *:.: :* : * ::* ::*:. :* * : : *:**: *:. :* : * : . : ::. .* *. :. : ::. . . : : ::* :.*: * ***.**: * :: . *: ::::: . ** :::: * **: : ::: :: :: .:: ::: ** *:. : **.* ***:.: *. * ***:* :. . * ..*:**: .::* : *. ** :..:* .. :. ** : :. :* : ::** :: : .: ** :: : *: ::. * :* . : : ..* :..**::** * *: *:. * .*: ::**:: ** : *:.:**::* . *:::.**: *.** ::* ** : .. . *: * ***:.*. . .* ::: *: :**. . * ::: : * .: :.. . :::.: *.:* . * . ** :*::.*: *.:.: .: ::*:::* .:** *** * :. ::: * . :*:::: **::**:::* ::**:::: :::. :* : * *.: . * *: : :. **:**::. ", "identical_positions": 155, "similar_positions": 295, "identity": "15.96%" }, { "cls_id": "homologset.agr.SGD:S000002826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23358-1", "uniprot_id": "RL12_RAT", "id": "P23358-1", "name": "Large ribosomal subunit protein uL11", "aln": "--------------------------------------MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHNGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZJE2-1", "uniprot_id": "D3ZJE2_RAT", "id": "D3ZJE2-1", "name": "Large ribosomal subunit protein uL11", "aln": "MILKRDQSPFRLSVRRRQRCNFLRSSRIRVHPTPATSTMPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVSSASALIIKALKEPPRDRKKQKNIKHNGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSSAVECPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30050-1", "uniprot_id": "RL12_HUMAN", "id": "P30050-1", "name": "Large ribosomal subunit protein uL11", "aln": "--------------------------------------MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35979-1", "uniprot_id": "RL12_MOUSE", "id": "P35979-1", "name": "Large ribosomal subunit protein uL11", "aln": "--------------------------------------MPPKFDPNEVKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CX54-1", "uniprot_id": "RL12B_YEAST", "id": "P0CX54-1", "name": "Large ribosomal subunit protein uL11B", "aln": "--------------------------------------MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********:* :***..******::*****************:****** ::**:::**:*.****** .**.***:*:*.***********:**:**.*** :***::******.:*:.* *:.. ************.** ::*****:.**:. :* * .", "identical_positions": 113, "similar_positions": 41, "identity": "55.67%" }, { "cls_id": "homologset.agr.SGD:S000002827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADZ0-1", "uniprot_id": "D4ADZ0_RAT", "id": "D4ADZ0-1", "name": "DNA polymerase eta", "aln": "-----------------MAPGQDLVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRNMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSHF-AVIERASIDEAYIDLTNAVQERLEKLQG----QPVSADLLPSTYIEGLPRGP-AVEDTVEKEDIRKQGLLQWLGSLEKDDPTSP----DLRLTVGAVIVEEMRAAIERKTGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIDVLGVEYMGDLTQFTEAQLQSHFGEKNGSWLYAMCRGIEHEPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLALELEERLTKDRTDNGRVATQLVVSIRVEGDKRLSSLRRCCALTRYDAHKMSQDAFATIRNCNTSG----VQTEWSPPLTMLFLCATKFSASAP----------PACTDITVFLSSDSGCQPKVPAASSGTRTQEPGP--------------------------AAPTSKEAATSLESFFQKAAKRQRMRETSFVPPKVAVEK----SSSKPSLLFQTSGSPGTKSFFKQKSLLLQHTE---LSN-----------------AAAPCPPQ----ASSAVQPSRLPTDRADSRASCEEVCKP-VSSKA----------------------------------------------------------------------------------------------VSTEVNVAGNS-----SLAYNS-QEMTQRAA--------EDQVLCEKCDSLVPVWDMPEHLDYHFALELQKSFLQPCTSKPQAVP-VSPQGKRNPKSPLASSNKRLRPHG---MQTLESFFKPLTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN0-1", "uniprot_id": "POLH_MOUSE", "id": "Q9JJN0-1", "name": "DNA polymerase eta", "aln": "-----------------MAPGQNRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRNMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSYF-AVIERASIDEAYIDLTSAVQERLQKLQG----QPISADLLPSTYIEGLPRGP-TVEETVQKEAIRKQGLLQWLDSLQSDDPTSP----DLRLTVGAMIVEEMRAAIESKTGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIEVLGIEYMGDLTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLALELEERLTKDRNDNDRVATQLVVSIRFQGDRRLSSLRRCCALPRYDAHKMSQDAFAAIRNCNTSG----IQTEWSPPLTMLFLCATKFSAAAP----------PACTDITAFLSSDSSCQPKVPIASSETRTQGSGP--------------------------AVPTSKEAATSLASFFQKAAKKQRMKETSFVPLNTATEK----LSSKPSLVFQSSQTTGSQSFFKQKSLLLQHTQ---LSN-----------------SAAPDPPQ----ASPAAQPSCLPAECVDS-GPDDGAVKP-VSSKA----------------------------------------------------------------------------------------------VSTEMNVAGDSPNVLDSPAYNS-QEVTQRAT--------EDQVLCEKCDSLVPVWDMPEHTDYHFALELQKSFLQPCTSKPQAIPAVSPQGKRNPKSPSASSSKRLRPHG---MQTLESFFKPLTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y253-1", "uniprot_id": "POLH_HUMAN", "id": "Q9Y253-1", "name": "DNA polymerase eta", "aln": "-----------------MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSRF-AVIERASIDEAYVDLTSAVQERLQKLQG----QPISADLLPSTYIEGLPQGPTTAEETVQKEGMRKQGLFQWLDSLQIDNLTSP----DLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSG----IQTEWSPPLTMLFLCATKFSASAP----------SSSTDITSFLSSDPSSLPKVPVTSSEAKTQGSGP--------------------------AVTATKKATTSLESFFQKAAERQKVKEASLSSLTAPTQAPMSNSPSKPSLPFQTSQSTGTEPFFKQKSLLLKQKQ---LNN-----------------SSVSSPQQNPW-SNCKALPNSLPTEYPGCVPVCEGVSKLEESSKA----------------------------------------------------------------------------------------------TPAEMDLAHNSQSMHASSASKSVLEVTQKATPNPSLLAAEDQVPCEKCGSLVPVWDMPEHMDYHFALELQKSFLQPHSSNPQVVSAVSHQGKRNPKSPLACTNKRPRPEG---MQTLESFFKPLTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7Z9-1", "uniprot_id": "F1Q7Z9_DANRE", "id": "F1Q7Z9-1", "name": "DNA polymerase eta", "aln": "-----------------MDFGKERVVALVDMDCFYVQVEQRLKPELKNKPCVVAQYKTWKGGGIIAVSYEARAHGVGRNMFADDARKLCPDLQVARVPEAHG---------------------------KADLTHYREASVEVIEVMSRF-AVIERASIDEAYMDLTASVQERLKNTSV----QDITAQQLKNTHIQGFPTQQ--ENTHLDRDAQRAAGLQQWLDLLSSSTESSPA---DLRLAVGALIVEQMRAAVEEHTGFRCSAGISHNKVLAKLACGLNKPNRQTVLPLSSVPQLFST--LPISKIRNLGGKLGSSITETLSVENMGDLTRFSRAQLEQHFGDKTGPWLYDLCRGIEFEPVKPRQLPKSIGCSKNFAGKTCLRTKQQVQYWLHQLALELEERLNKDRDVNGRVARQLTVGVRQAGGQRSGSFSRCCALVRYDAMKMTNDSLTIIKSLNTAGA---HQEAWSPALTLLHLSASKFSDAPS----------SSSAGITGFLSSDAASSPSQSSSSQRSPMERPAQKRKRQ---------------------QDQRQRENTTSISAFFQRKSLEKQEIQNSLCPGDQSTSA----SGEHACGDTAAQKTTAISTFLQRESLEKQEIQNVSLDDE---------------DQSVCAPEENTCREKPAGISTSLQMKSLEKHQIQNSLCVGDQSVRAPGENPPREQTSDESPAGI--------------------------------------------------SSFFQMKSLEKHRIQNSPCTGDPNIRAPAENTSRDQTSERSTSGMSGCFQQAVAPAGERVCSPAEEDLQVCERCGMKVLVWEFPEHADYHFALDLQKSFSSGSPSQ--------------MKTPSGSQAKRARVQEP--RGTLHSFFKKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX1-1", "uniprot_id": "POLH_DROME", "id": "Q9VNX1-1", "name": "DNA polymerase eta", "aln": "--------MSSARSHVSMQNKYDRVVLLVDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGGGIIAVNYAARAKGVTRHMRGDEAKDLCPEIVLCQVPNIRE---------------------------KADTSKYRDAGKEVANVLQRFTQLLERASVDEAYLDITETVNHRMQQMQSGA--FALQPQELVNTFAVGYPSIGDYVNKITNRFANPYMDDERYQMSYDQNDLPAVRQS-DIRLLIGASVAGEVRAAVKKETGYECSAGIAHNKILAKLAAGMNKPNKQTILPLTETASLFDS--LPVGKIKGLGGKFGEVVCETLGIKFMGQVVKFSEVDLQRKFDEKNGTWLFNISRGIDLEAVTPRFYSKSIGCCKKFPGRNNITGLKTLQHWLGELSSEINDRLEKDFIENNRRAKHMVVQYVQDIDGEEVASSRSTALRDYDQESIVRLSLDLIKANTKTFLRPGSESALNNAIKFLGISVGKFETVSSGQNKLQEMFANQAAKKRRVSGDEPGQLPKVEMEKKQKQTDEFKMKSFFANYLQGAKKEDAKADGISANPLAAAAGAPNKNFVEEYKHKLHAAVRTEGTVLTSTPAEFKESFFSQYLKQQKKTGQQGSVTSREDSLDVQELAEELDAIEADNSKDFEEDTEEETELTSDTHMSKPEGQSSDAGQEQDPNTLNDSTGNDLYVETGIVPPTLTEDELKPSTSKRKFDEIESSVSNYKECYVEFAVPNLRTDILPTIKCDQCGANIPDEVKSLQTHRDHHFAQELSRTLRSTEREERTQSRQKISLKPTPPKKSKKTAGSGSSSYSTAPPSNSITKFFRAKPTQEQAPSDPQMNQCPECKAFIKCVDMPEHLDYHVARNLQRELNQQDLRTRTAALNKEKISPVQPKKQSQKKLNSTISASSSGTKTIAQFFSQSN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04049-1", "uniprot_id": "POLH_YEAST", "id": "Q04049-1", "name": "DNA polymerase eta", "aln": "MSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKEDPVVCVQWN-----SIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRET------------WPDNAGQLKEFLDAKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSS----------RPVVKSMMSNKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIP------RTVSISLKTKSYEVYRKSGP-----------VAYKGINFQSHELLKVGIKFVTDLDIKGK-----------------------------------------NKSYYPLTKLSMTITNFDIIDLQKTVVD------MFGNQVHTFKSSAGKEDEEKTTSSKADEKT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKLECCKYQVTFTDQKALQEHADYHLALKLSEGLNGAEESSKNLSFGEKRLLFSRKRPNSQHTATPQKKQVTS-SKNILSFFTRKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:.*: ***: :: * . .*:: .****.* ** *: * ::* . *.:: :. : *.. ** . :. :::. ::****:**.::*: . : . : . .. . : . . . *: * :*: : :* ::: *: *.*:: .* :.***.. :**: **:: .::. : : .: *** :* : : *.: ..: :: . * : : .. : . .: . :. : .: . . :.. * . : : . : . : .: : .. . .:.: . : . . . . : . . : : . : . .. . * : ** ***.* .*.. : : . .: .**. ", "identical_positions": 61, "similar_positions": 157, "identity": "6.59%" } ]